<?xml version="1.0" encoding="UTF-8"?>
<uniprot xmlns="http://uniprot.org/uniprot"
 xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance"
 xsi:schemaLocation="http://uniprot.org/uniprot http://www.uniprot.org/docs/uniprot.xsd">
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GS85</accession>
    <name>A0A2S9GS85_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4735</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000058">
        <property type="protein sequence ID" value="PRC90556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90556">
        <property type="protein sequence ID" value="PRC90556"/>
        <property type="gene ID" value="S2091_4735"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025948">
        <property type="entry name" value="HTH-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13276">
        <property type="entry name" value="HTH_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00665">
        <property type="entry name" value="rve"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13333">
        <property type="entry name" value="rve_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50994">
        <property type="entry name" value="INTEGRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase catalytic" evidence="1">
        <location>
            <begin position="96"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="260" mass="30614" checksum="D77719BE853BCE1B" modified="2018-07-18" version="1">MARSTFYYQQKALMVKDKYADLKKHIRTIYARHKGRYGYRRITASIKQLGINVNHKTVQRLMAELGLKSLVRIKKYRSYKGNVGRIAPNLLQRQFVAEKANQKWVTDVTEFNVAGEKLYLSPILDLYNGEIIAYETSRRPVFKMVSDMLKKAWAKLKPDDKPMLHSDQGWQYQMSAYQRILEQRQVVQSMSRKGNCLDNAAMESFFAVLKSEYYYLNKFKTIEELEKGLANYIRYYNYDRIKLKLKGLSPVQYRNQPSVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSB6</accession>
    <name>A0A2S9GSB6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ankyrin repeats (3 copies)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4682</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000044">
        <property type="protein sequence ID" value="PRC90614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90614">
        <property type="protein sequence ID" value="PRC90614"/>
        <property type="gene ID" value="S2091_4682"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13857">
        <property type="entry name" value="Ank_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="SSF48403"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="37"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="70"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="131" mass="14343" checksum="0B138C2AE4605A01" modified="2018-07-18" version="1">MINDLKTVFAKIASHTYYLDDDRNEVDLVDVNQRDWSGDSPLHIAVILGDISIVEVLLDNGADVNALDERQFTALHFAAMKNNAEIIVVLLDKGADRNIKNDDGRKPLDCAISAGSSAAISVLKSKVHKKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSE9</accession>
    <name>A0A2S9GSE9_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">ATP synthase subunit alpha</fullName>
            <ecNumber evidence="14">7.1.2.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">ATP synthase F1 sector subunit alpha</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="14">F-ATPase subunit alpha</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">atpA</name>
        <name evidence="18" type="ORF">S2091_4652</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 14">Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>ATP + 4 H(+)(in) + H2O = ADP + 5 H(+)(out) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:57720"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="7.1.2.2"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="13">F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="14">Cell membrane</location>
            <topology evidence="14">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 14">Belongs to the ATPase alpha/beta chains family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.1.2.2" evidence="14"/>
    <dbReference type="EMBL" id="PUGF01000041">
        <property type="protein sequence ID" value="PRC90644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90644">
        <property type="protein sequence ID" value="PRC90644"/>
        <property type="gene ID" value="S2091_4652"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045261">
        <property type="term" value="C:proton-transporting ATP synthase complex, catalytic core F(1)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd18113">
        <property type="entry name" value="ATP-synt_F1_alpha_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01132">
        <property type="entry name" value="F1_ATPase_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.150.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01346">
        <property type="entry name" value="ATP_synth_alpha_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023366">
        <property type="entry name" value="ATP_synth_asu-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000793">
        <property type="entry name" value="ATP_synth_asu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038376">
        <property type="entry name" value="ATP_synth_asu_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033732">
        <property type="entry name" value="ATP_synth_F1_a"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005294">
        <property type="entry name" value="ATP_synth_F1_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020003">
        <property type="entry name" value="ATPase_a/bsu_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004100">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036121">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000194">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_nucl-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00006">
        <property type="entry name" value="ATP-synt_ab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00306">
        <property type="entry name" value="ATP-synt_ab_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02874">
        <property type="entry name" value="ATP-synt_ab_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039088">
        <property type="entry name" value="F_ATPase_subunit_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50615">
        <property type="entry name" value="SSF50615"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00962">
        <property type="entry name" value="atpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00152">
        <property type="entry name" value="ATPASE_ALPHA_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12 14" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="7 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 14" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="11 14" id="KW-0139">CF(1)</keyword>
    <keyword evidence="6 14" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="9 14" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 14" id="KW-1278">Translocase</keyword>
    <keyword evidence="3 14" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ATP-synt_ab_N" evidence="17">
        <location>
            <begin position="26"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-synt_ab" evidence="15">
        <location>
            <begin position="149"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-synt_ab_C" evidence="16">
        <location>
            <begin position="382"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <begin position="169"/>
            <end position="176"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="site" description="Required for activity" evidence="14">
        <location>
            <position position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00026013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF00306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF02874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="PRC90644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="513" mass="55035" checksum="B2185DD9029B9ACC" modified="2018-07-18" version="1">MQLNPSEISELIKSRIEGLSSSAEVRNEGTVISVTDGICRVHGLSDAMQGEMLEFPGNTFGLALNLERDSVGVVILGDYEHISEGDTVKCTGRILEVPIGPELRGRVVNALGQPIDGKGPINAKLTAPIEKIAPGVIARQSVSEPLQTGLKSIDSMVPVGRGQRELIIGDRQTGKTAVAIDTVINQKGQNVTCIYVAIGQKASSIKNVVRSLEAHGAMEYTIVVAASASESAAMQYVSAYSGCAMGEYFRDRGQDALIIYDDLSKQAVAYRQVSLLLRRPPGREAYPGDVFYLHSRLLERAARVNPDYVEKFTNGEVKGKTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLETSLFNAGIRPAINAGISVSRVGGAAQTKVIKNLSGGIRTDLAQYRELAAFAQFASDLDEATRKQLDRGARVTELLKQAQYSPLSISLMAVTLFSVNKGFLDDVPVKKVLDFEAGVHSYMKTSHAALLQKIEETKQLDKDGEAVLSAAIADFKKSGAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSF6</accession>
    <name>A0A2S9GSF6_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">ATP synthase epsilon chain</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">ATP synthase F1 sector epsilon subunit</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">F-ATPase epsilon subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">atpC</name>
        <name evidence="15" type="ORF">S2091_4655</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 10">Produces ATP from ADP in the presence of a proton gradient across the membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 10 11">F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cell membrane</location>
            <topology evidence="10">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10 11">Belongs to the ATPase epsilon chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000041">
        <property type="protein sequence ID" value="PRC90647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90647">
        <property type="protein sequence ID" value="PRC90647"/>
        <property type="gene ID" value="S2091_4655"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045261">
        <property type="term" value="C:proton-transporting ATP synthase complex, catalytic core F(1)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd12152">
        <property type="entry name" value="F1-ATPase_delta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00530">
        <property type="entry name" value="ATP_synth_epsil_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036794">
        <property type="entry name" value="ATP_F1_dsu/esu_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001469">
        <property type="entry name" value="ATP_synth_F1_dsu/esu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020547">
        <property type="entry name" value="ATP_synth_F1_dsu/esu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020546">
        <property type="entry name" value="ATP_synth_F1_dsu/esu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036771">
        <property type="entry name" value="ATPsynth_dsu/esu_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13822">
        <property type="entry name" value="PTHR13822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00401">
        <property type="entry name" value="ATP-synt_DE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02823">
        <property type="entry name" value="ATP-synt_DE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46604">
        <property type="entry name" value="SSF46604"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51344">
        <property type="entry name" value="SSF51344"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01216">
        <property type="entry name" value="ATP_synt_epsi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10 11" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="10" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 10 11" id="KW-0139">CF(1)</keyword>
    <keyword evidence="12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="10" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="6 10 11" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10 11" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ATP-synt_DE_N" evidence="14">
        <location>
            <begin position="5"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-synt_DE" evidence="13">
        <location>
            <begin position="90"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="93"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005712"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00530"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="PRC90647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="140" mass="14945" checksum="F88FAE14D510022C" modified="2018-07-18" version="1">MAHTIQVDVVSAEESIFSGLAEFVALPGEAGELGIYPQHTPFITRIKPGSVRIKIPGQTEEVFVFVAGGLLEVQPTAVIVLADSAIRGKDLDEAKATEAKKRAEDALANREANIDFAQAHAELSAAVAQLAAISRLRQKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSJ7</accession>
    <name>A0A2S9GSJ7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative metal-dependent phosphoesterases (PHP family)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4587</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000038">
        <property type="protein sequence ID" value="PRC90694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90694">
        <property type="protein sequence ID" value="PRC90694"/>
        <property type="gene ID" value="S2091_4587"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004013">
        <property type="entry name" value="PHP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003141">
        <property type="entry name" value="Pol/His_phosphatase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016195">
        <property type="entry name" value="Pol/histidinol_Pase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02811">
        <property type="entry name" value="PHP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00481">
        <property type="entry name" value="POLIIIAc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89550">
        <property type="entry name" value="SSF89550"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="POLIIIAc" evidence="1">
        <location>
            <begin position="4"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="277" mass="30275" checksum="66DFD9924B9C039F" modified="2018-07-18" version="1">MLNIDLHCHSTVSDGLLSPADVATRAHNNGVDVWALTDHDEIGGISVARATAKELGMRHVAGVEISITWAGHTIHIVGLQIDETNPQLVQGLYDTRHGREKRAQQIGEMLAEVGIPNAYQGALHYVGNPDLISRTHFARYLVESGTCRDISDVFKNYLVEGKPGYVEHRWASLKDALTWIKGAGGVAVVAHPGRYDLTQLEMSAFLDEFKQYGGLGIEVVTGSHTPDQYAEYAKIAQQYGFLASRGSDFHGPGESKTELGALPPLPGNLVPVWHDWF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSS4</accession>
    <name>A0A2S9GSS4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DoxX-like family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4503</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000036">
        <property type="protein sequence ID" value="PRC90755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90755">
        <property type="protein sequence ID" value="PRC90755"/>
        <property type="gene ID" value="S2091_4503"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025695">
        <property type="entry name" value="DoxX-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13781">
        <property type="entry name" value="DoxX_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="56"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="83"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="110"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="129" mass="15187" checksum="96DBF0A45330F179" modified="2018-07-18" version="1">MSMYQREQKLNQLYWAVRFGLAFIWIWTAIVSWFIYPQAESLMWLRKVGVTYQPVMWLMGACLFDLAMGIASAFFASKRIWQAQLLMVIFYSLVIALELPEFLFHPFGPITKNIAVVGCLFYLLIMEKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GT17</accession>
    <name>A0A2S9GT17_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4441</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000034">
        <property type="protein sequence ID" value="PRC90860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90860">
        <property type="protein sequence ID" value="PRC90860"/>
        <property type="gene ID" value="S2091_4441"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC90860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="186" mass="21142" checksum="CC66E38130948F6A" modified="2018-07-18" version="1">MKHTEASAEWSKSFPNAAPAGFLCRDAYADRWLRVHSLPESKRYAELESERLEILRRHNTVACDLLGEGSDCILFLGRFGPEKLWQDERNIPLSAILPIHAMTYECDDDELQFFSAPVIWHKDKFNDLILASADDLTGPVMFANTKLGTAYAPYDGGADLFYPTHLDVGHARLNYRTWFSTRDDGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GT83</accession>
    <name>A0A2S9GT83_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative phosphotransferase related to Ser/Thr protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4333</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000032">
        <property type="protein sequence ID" value="PRC90932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90932">
        <property type="protein sequence ID" value="PRC90932"/>
        <property type="gene ID" value="S2091_4333"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="APH" evidence="1">
        <location>
            <begin position="24"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="332" mass="37583" checksum="98B8E1D6C8E1BFEE" modified="2018-07-18" version="1">MSIRDLERRRFISAAGIAPSPCIALAADASSRCYFRLPNAQPAQLLMDMEPDSPDLSAYILISHYLNNIGLSAPRVLRSNSATGLTLIDDFGTQTYTSALANGHDETTLYELAVDALVTLHSAQHVPHELPTYDMAALISEVELFLHWYLPELKQGATKFGQQFIQRWQEALSDVAQRRDALVLRDYHVDNLMIIPERIGTAACGLLDFQDALIGSRAYDLMSLCQDARRDLSDGLEQHLITRYLNAMPEINHPQFLSDYWLLAAQRHTKVAGIFERLARRDGKYQYLRHQPRVVRLLRQALEQANLQAITNLLDQHFPHWEIVGLPIKQSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTE9</accession>
    <name>A0A2S9GTE9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phage protein D</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4281</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000031">
        <property type="protein sequence ID" value="PRC90985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90985">
        <property type="protein sequence ID" value="PRC90985"/>
        <property type="gene ID" value="S2091_4281"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="330"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="330"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="409" mass="45365" checksum="5D5FF855A40B3811" modified="2018-07-18" version="1">MITRYPSPGFLITLDEQDITGKIAPRLVSLTLTECAGDDSDQLDLTLSDADGKLAIPPRGAKINLHIGWAQDGLVNKGEFTVDEVEHSGTPDQITLRARTANLIDAFRQLQEASFHDTTLGAIIELIAFKNELQSGIADSLRNVVVMHLDQTRESDAAFLRRLGKKYDATATVKNNTLLFIPTNQSKTASGKALPIIHLTRQLGDSHRYHSSERDSYSGVRVFWHDQKYAVRKSVVAGNPGNSKRLRTTYANETDARQAAVAEWQRLQRGLATFELALALGNPALMPKSPVTVSGFKDAIDQVEWQAVKTIHSISDGGFTTRIELETKVEEAEAEREPQTDPDEGITGVLTKWKEKGRNRSGEELAGSTDNAKTLELVYASRQYAAKTARDQWVEIQERREIIAENNRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTH7</accession>
    <name>A0A2S9GTH7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">HAD-SF-IB-hyp1: HAD hydrolase, family IB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4311</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000031">
        <property type="protein sequence ID" value="PRC91015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91015">
        <property type="protein sequence ID" value="PRC91015"/>
        <property type="gene ID" value="S2091_4311"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006385">
        <property type="entry name" value="HAD_hydro_SerB1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01490">
        <property type="entry name" value="HAD-SF-IB-hyp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="224" mass="25202" checksum="7FD54DA71FFBC5D2" modified="2018-07-18" version="1">MNPANIAIFDLDHTLLPIDSDYEWGRFLCRIGAVDKTYFEQRNHDFFAQYQAGCLDAREYLEFALGTLAQFSQSQLTTLHQQFMTEVINPLLLPAAYELLARHKDDLIIIITATNRFVTEPIAHALGVQHLIAAQPEISTDGRLTGKLCGNPTSGEGKVEHLNAWLAQHNTTLNSFERSYFYSDSHNDLPLLKLVSHPVATNPNAQLSAHAHIHGWPILKIFND</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTM3</accession>
    <name>A0A2S9GTM3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phage/plasmid replication protein, protein II/X family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4226</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000030">
        <property type="protein sequence ID" value="PRC91038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91038">
        <property type="protein sequence ID" value="PRC91038"/>
        <property type="gene ID" value="S2091_4226"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006516">
        <property type="entry name" value="G2P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022686">
        <property type="entry name" value="G2P_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05144">
        <property type="entry name" value="Phage_CRI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01629">
        <property type="entry name" value="rep_II_X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phage_CRI" evidence="1">
        <location>
            <begin position="77"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="396" mass="45839" checksum="0CF5DB6D634F558A" modified="2018-07-18" version="1">MAYDTIKLKSPALLKYVVDHVQNQCFLRTGVEMQTGDVRYEIFAGELLGSWDARISVIPKYEDFVLNSAGRPVLVPCEPYLVIEASVHKIFTGHNVYGGPTDFQDVCAKFIKLIATLLNVELPNARMWTVHRVDVALVYKLSKPACKEFFDGMQLISFPRRKKGSAKYAMAVYFAGKTTTVKFYHKGSEFAVHEKARLRNFFFNLFNHLHGVDDPKNKQRVERKIQALQRLADNRLRVEVEIHSDKLQYDYEKNPRVDEVTDSYLAQVYDKEVEKLLREGKQGMDTVKETRAVMRRLQMNYGKSSGTRLYGFWSSLCTLGDEVTKEQFPKTVFYRNRKQLEDAGVSWRGTDIQIIANDKLIPHDFSPIRSDKRLCYLPARNREMYNVSRETMRQAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTN3</accession>
    <name>A0A2S9GTN3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4236</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000030">
        <property type="protein sequence ID" value="PRC91048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91048">
        <property type="protein sequence ID" value="PRC91048"/>
        <property type="gene ID" value="S2091_4236"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="70" mass="7822" checksum="F3C9716ADF94966D" modified="2018-07-18" version="1">MNADSDIVRTHVVDERSDMETELAVNRGLAVALLDGVREGVKIMQDEGVPIEICSRVLKNKANRRASDWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTX2</accession>
    <name>A0A2S9GTX2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">PPIC-type PPIASE domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_4080</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000027">
        <property type="protein sequence ID" value="PRC91185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91185">
        <property type="protein sequence ID" value="PRC91185"/>
        <property type="gene ID" value="S2091_4080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000297">
        <property type="entry name" value="PPIase_PpiC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027304">
        <property type="entry name" value="Trigger_fact/SurA_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109998">
        <property type="entry name" value="SSF109998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50198">
        <property type="entry name" value="PPIC_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0413">Isomerase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0697">Rotamase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="domain" description="PpiC" evidence="3">
        <location>
            <begin position="265"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC91185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="643" mass="70791" checksum="9304AEF7500DCFBE" modified="2018-07-18" version="1">MFEYVRTHQRLMQFILLLFIVPSFALVGISSYVRGNNEETVAKVAGENISQQEFDDALRQQMDKMRQRFGDKFDEAMFNTVEAKKSILDNLIAQRVLRAEVKNQNLSIPDQVLQQNILAIPGLTLPNGSFDNEGYKNALAAQRLTPTMYESGERERLAQQQLTTAIEGSAFVPKAVLAQVNAITSQEREIQSIDFKAADFVSQVKITDAMLKAYYDKNGAQFQIPEMAKIEYVVLSGETIAAQMTASDEEIKAYYDQNIKNYSVDEQRRASHILIKVNKGASAAEKAAAKAKAEEVLALVRKQPENFAQLAKQYSEDEGSKAQGGDLDFFAKGMMLKPFEDATYKLKENEISDLVESDFGFHIIHLTAIKPTSVKPLDQVKDQISADIKKQKAGKKFSEMAETFTNTVYEQSTSLQPVADKLKLTIATADNLTRVPNSVNHSNPILANPKFLKALFSDDAIKNKRNTEALELGANTLVSARIVEHKPASKRPFDEVKDVITARVTLAESESLAQKAGQAKLASLIATPDAAGFGDTKLVSRIQQGGIPGAAFDLIMKADTRKLPAFVGVELPGQAYAVYRINKIQQAAPDEGRTAEIAKQVDNVTASDEFFAYVEMLKQKGNVKIVKPFVATPAELAGAKAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTY1</accession>
    <name>A0A2S9GTY1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4165</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000028">
        <property type="protein sequence ID" value="PRC91164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91164">
        <property type="protein sequence ID" value="PRC91164"/>
        <property type="gene ID" value="S2091_4165"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="128" mass="14153" checksum="AE707DC63D8463D5" modified="2018-07-18" version="1">MRATVPKIVTYGAVGLFGLIVASIAHRLNVVSEAAQNTTEFCQSVKPGDDVSFIMKKVGHGESGVQFNTIYEQREGQPTWPRHVIWNGPHYKRVYCSLEIGSHGDVLATHIGPIDEKTPGFFEDWIGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTZ6</accession>
    <name>A0A2S9GTZ6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NADH:flavin oxidoreductases Old Yellow Enzyme family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4102</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000027">
        <property type="protein sequence ID" value="PRC91207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91207">
        <property type="protein sequence ID" value="PRC91207"/>
        <property type="gene ID" value="S2091_4102"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001155">
        <property type="entry name" value="OxRdtase_FMN_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045247">
        <property type="entry name" value="Oye-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22893">
        <property type="entry name" value="PTHR22893"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00724">
        <property type="entry name" value="Oxidored_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Oxidored_FMN" evidence="1">
        <location>
            <begin position="4"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="363" mass="39158" checksum="9FA5A7D8DAD795A6" modified="2018-07-18" version="1">MYKKLLSPVTTGSIALTNRVVMAPLTRSRAGQGDVPRALNVEYYQQRASAGLIVTEASQISRQGQGYAWTPGIYTDEQEAGWKQVVAAVHAKGGRIALQLWHVGRISHSLLQENGGAPVAPSALLAENSQSFVVLPDGTPANVPTEMPRALELTEMPGIVAQYRQAAQRAKRAGFDLVEVHAANGYLLQQFMSTNSNHRTDIYGGSLENRARLSLEAVDAAIAEMGADRVGVRISPHFVAHGILDTEADAMALYLAKEFSARGIAYLHVAEPDWAGGPLLSDAFRNQLRSVFKGTLIYCGNYSAAEAETLIEQGFGDAVAFGRPFIANPDLVTRFSQGAELNMPDRATFYGGDAKGYTDYPTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GU10</accession>
    <name>A0A2S9GU10_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Histidine utilization repressor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_4120</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000027">
        <property type="protein sequence ID" value="PRC91225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91225">
        <property type="protein sequence ID" value="PRC91225"/>
        <property type="gene ID" value="S2091_4120"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006547">
        <property type="term" value="P:histidine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006744">
        <property type="term" value="P:ubiquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07377">
        <property type="entry name" value="WHTH_GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1410.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028978">
        <property type="entry name" value="Chorismate_lyase_/UTRA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010248">
        <property type="entry name" value="His_ut_repres"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011663">
        <property type="entry name" value="UTRA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00392">
        <property type="entry name" value="GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07702">
        <property type="entry name" value="UTRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00035">
        <property type="entry name" value="HTHGNTR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00866">
        <property type="entry name" value="UTRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64288">
        <property type="entry name" value="SSF64288"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02018">
        <property type="entry name" value="his_ut_repres"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50949">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0831">Ubiquinone biosynthesis</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="3">
        <location>
            <begin position="10"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC91225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="238" mass="27300" checksum="33DE39BE5AB4D329" modified="2018-07-18" version="1">MPAHDPHINGSLFQRIKDYILAEIHLGHWREGDVIPTEQALSKQFVVSRMTVNRALRELTSEQILMRIQGSGTFVAQQKYKATLIKVKNIAEEIKDRAHTHRSELLCLERCKANEQQAKQFQVNHNHMLFHSTIVHFENDIPIQIEDRWVNSEVAPEYIQQNFHAITPNEYLMKAAPLQGADYSIEACNAPTEIAELLAMTSKDPCLVLNRTTKSMGRIASVATMWHPGHRYQFTGQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GU26</accession>
    <name>A0A2S9GU26_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Major Facilitator Superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_4104</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000027">
        <property type="protein sequence ID" value="PRC91209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91209">
        <property type="protein sequence ID" value="PRC91209"/>
        <property type="gene ID" value="S2091_4104"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="32"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="76"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="106"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="132"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="170"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="205"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="259"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="296"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="328"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="358"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="390"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="416"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="7">
        <location>
            <begin position="32"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC91209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="443" mass="48101" checksum="1C0BB7192568DD9A" modified="2018-07-18" version="1">MNSTQTSMPHAASSSKNSAMHSRSLNKSDVKVLSLASLGGALEYYDFIIFIFFASVFSGQFFPADLSPFWKTLNTYGAFAIAYFMRPIGGVIMAHFGDLVGRKRMFTLSIVLMALPTLCIGFLPTFEHIGYAAPILLLLMRMLQGIAIGGEIPGAWVFVSEHVPAKRIGLANGMVTSGLTLGILLGSLMALLINSTFSKSDIAEYAWRIPFIVGGLLGFVTVYLRRYLHETPVFKEMQERKALNQGLPIAAVIKDHKPAILISVLATWLLTAGIVVIILFAPELMKSDIFNVPAKVALTMQSFTIVALALGCITTGQLCDKFGVGKTFIVMCSALAISSSVFYHSIGHVDYPTLTVMYAITGFFVGIVGGVPYIMVHAFPAKIRFSGLSFSYNLSYAIFGGLTPLFLGIVNKINPLSASYYVVFLSIMGVFCGIYLLKDSAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GU31</accession>
    <name>A0A2S9GU31_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltransferase domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4030</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000026">
        <property type="protein sequence ID" value="PRC91245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91245">
        <property type="protein sequence ID" value="PRC91245"/>
        <property type="gene ID" value="S2091_4030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_25" evidence="1">
        <location>
            <begin position="54"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="207" mass="23157" checksum="522E11B058BAB04B" modified="2018-07-18" version="1">MTLPPPDLTAISARTREHYENNAENFKIGTQDHDVSQNINALLNQIHVTAPYTILDFGCGPGRDLASFKQLGHYAIGLDGTAKFVEMARAATGCEVWHQDFLQLDLPGNYFDGIFANASLFHIPSQELPRILRQLNACLKPGGVLFSSNPRGTGQEGWSGDRYGAYHSLETWRSYLTDAGFTERAHYYRPEGLPRDQQPWLATVFVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GU44</accession>
    <name>A0A2S9GU44_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">Dihydrofolate reductase</fullName>
            <ecNumber evidence="3 7">1.5.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">S2091_4015</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 7">Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>(6S)-5,6,7,8-tetrahydrofolate + NADP(+) = 7,8-dihydrofolate + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:15009"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57451"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.5.1.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 7">Cofactor biosynthesis; tetrahydrofolate biosynthesis; 5,6,7,8-tetrahydrofolate from 7,8-dihydrofolate: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7 8">Belongs to the dihydrofolate reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.5.1.3" evidence="3 7"/>
    <dbReference type="EMBL" id="PUGF01000026">
        <property type="protein sequence ID" value="PRC91230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91230">
        <property type="protein sequence ID" value="PRC91230"/>
        <property type="gene ID" value="S2091_4015"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00077">
        <property type="reaction ID" value="UER00158"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004146">
        <property type="term" value="F:dihydrofolate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006545">
        <property type="term" value="P:glycine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006730">
        <property type="term" value="P:one-carbon metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046654">
        <property type="term" value="P:tetrahydrofolate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00209">
        <property type="entry name" value="DHFR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.430.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012259">
        <property type="entry name" value="DHFR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024072">
        <property type="entry name" value="DHFR-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017925">
        <property type="entry name" value="DHFR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001796">
        <property type="entry name" value="DHFR_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48069">
        <property type="entry name" value="PTHR48069"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00186">
        <property type="entry name" value="DHFR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000194">
        <property type="entry name" value="DHFR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53597">
        <property type="entry name" value="SSF53597"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00075">
        <property type="entry name" value="DHFR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51330">
        <property type="entry name" value="DHFR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0521">NADP</keyword>
    <keyword evidence="7" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="5 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DHFR" evidence="9">
        <location>
            <begin position="3"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009539"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00025067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR000194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC91230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="162" mass="18253" checksum="A6FCE4CB3EE7B455" modified="2018-07-18" version="1">MSELTIIVAYDAKRGIGINNTLPWRLPEDLARFKRITTGHAIIMGRKTFASIGRPLPNRRNIVLTRNTDWQQDGVEVVNSLPAALQLIGNTDAFIIGGADIYAQALPLCSQLLVTEIHQDVECDAFFPAIDQDVWQETERTTFHSEQNAFDYAFVTYTKIKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GU91</accession>
    <name>A0A2S9GU91_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Membrane protein related to metalloendopeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_4063</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000026">
        <property type="protein sequence ID" value="PRC91278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91278">
        <property type="protein sequence ID" value="PRC91278"/>
        <property type="gene ID" value="S2091_4063"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00118">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011055">
        <property type="entry name" value="Dup_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036779">
        <property type="entry name" value="LysM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016047">
        <property type="entry name" value="Peptidase_M23"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01476">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01551">
        <property type="entry name" value="Peptidase_M23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00257">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51261">
        <property type="entry name" value="SSF51261"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51782">
        <property type="entry name" value="LYSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015752302" evidence="2">
        <location>
            <begin position="24"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="3">
        <location>
            <begin position="63"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC91278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="319" mass="33617" checksum="6EFEBF617AD28ADC" modified="2018-07-18" version="1">MKCNRMKSIKNVTLFLVVSSVLAACGTTTVRAPIEDRNPQANKNQAGPGGTPATGAKAEDLQSQYVVKKGDTLYRIALDKGQSYSDIVTWNNLANPNDIKVGQVLRVAPPDAGSGGQTTGVASPSGVEVRPLGAGAVASAPSGNNKNAPRADKRPYSDAALADLQKNETADASSAKVIAKPIDKTAEKTVDPVIVDEIVWVWPVDGKVVANFDDNKSKGIDVSGKLGQDIYAAAAGTVMYAGSGIRGYGNLVIIKHSNNLLSAYAHNKLIVVKEKQIISKGQKIAEMGNSDSDSGVVKLHFEIRQQGKPVDPMKFLPGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUF4</accession>
    <name>A0A2S9GUF4_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="11 12">DNA ligase</fullName>
            <ecNumber evidence="11 12">6.5.1.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Polydeoxyribonucleotide synthase [NAD(+)]</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">ligA</name>
        <name evidence="14" type="ORF">S2091_4004</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 11">DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="11">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the NAD-dependent DNA ligase family. LigA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.5.1.2" evidence="11 12"/>
    <dbReference type="EMBL" id="PUGF01000025">
        <property type="protein sequence ID" value="PRC91333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91333">
        <property type="protein sequence ID" value="PRC91333"/>
        <property type="gene ID" value="S2091_4004"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003911">
        <property type="term" value="F:DNA ligase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00114">
        <property type="entry name" value="LIGANc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01588">
        <property type="entry name" value="DNA_ligase_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041663">
        <property type="entry name" value="DisA/LigA_HHH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018239">
        <property type="entry name" value="DNA_ligase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033136">
        <property type="entry name" value="DNA_ligase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001679">
        <property type="entry name" value="DNAligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013839">
        <property type="entry name" value="DNAligase_adenylation"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013840">
        <property type="entry name" value="DNAligase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003583">
        <property type="entry name" value="Hlx-hairpin-Hlx_DNA-bd_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004150">
        <property type="entry name" value="NAD_DNA_ligase_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010994">
        <property type="entry name" value="RuvA_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004149">
        <property type="entry name" value="Znf_DNAligase_C4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00533">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01653">
        <property type="entry name" value="DNA_ligase_aden"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03120">
        <property type="entry name" value="DNA_ligase_OB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03119">
        <property type="entry name" value="DNA_ligase_ZBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12826">
        <property type="entry name" value="HHH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001604">
        <property type="entry name" value="LigA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00292">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00278">
        <property type="entry name" value="HhH1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00532">
        <property type="entry name" value="LIGANc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47781">
        <property type="entry name" value="SSF47781"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="SSF52113"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00575">
        <property type="entry name" value="dnlj"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01055">
        <property type="entry name" value="DNA_LIGASE_N1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01056">
        <property type="entry name" value="DNA_LIGASE_N2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11 12" id="KW-0227">DNA damage</keyword>
    <keyword evidence="9 11 12" id="KW-0234">DNA repair</keyword>
    <keyword evidence="3 11 12" id="KW-0235">DNA replication</keyword>
    <keyword evidence="2 11 12" id="KW-0436">Ligase</keyword>
    <keyword evidence="7 11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="10 11" id="KW-0464">Manganese</keyword>
    <keyword evidence="4 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 11 12" id="KW-0520">NAD</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="BRCT" evidence="13">
        <location>
            <begin position="615"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="active site" description="N6-AMP-lysine intermediate" evidence="11">
        <location>
            <position position="134"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="47"/>
            <end position="51"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="96"/>
            <end position="97"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="132"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="155"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="192"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="313"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="337"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="431"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="434"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="456"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="PRC91333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="693" mass="75614" checksum="13618FDAABB92803" modified="2018-07-18" version="1">MQTDLFNPADPAPNHQKNAAQLAEQYRHSLNQYNNEYYVLDAPSVPDAEYDRLFKLLQELEAEHPNLATPDSPTLRVGGAALPAFQQVRHTVPMLSLNNGFEDADVHAFVRRAEEGLQSELGKIPAIAYVADLKFDGLAISLLYRDGLLIQAATRGDGSVGEDVTENIRTIRAIPLRLLGEHPPALLEVRGEVLMFKEDFSKLNARQRELELKEFANPRNAAAGSLRQLDAKITAQRNLRFFAYGLAQFEAGTEDSEAPVTHSALLAWYSQLGIPVCKEQTQAASADELLNFYRAIEQKREQLPYEIDGVVYKVNSFAQQQQLGFVSRAPRFAMAHKFPAQEQLTTVLDIEVQVGRTGAITPVARLAPVAVGGVIVTNATLHNEDEIRRKDVWIGDVVIVRRAGDVIPEVVAAVPAQRPASARQFVMPTHCPHCGSLIVKLEEEAIARCSAGWIKCSAQRKGGLWHFASRKAMCIDGLGEQLLDQLVDKNVITTAADLYNLGFTSLATLDRMADKSANNVIAAIEASKKTTLARFIYALGIRHVGETTAKDLARAFGDIHAVMDATEERLLQVNEVGPVVANSLIAFFADPLNKEVVEQLLAAGVHWPQAEESPTNTQIFTGKTVVLTGTLPNLSREQAAALIEAAGGKVQSSVSKKTSMVLAGEDAGSKLVKAQELGVQIISEAELQQMLGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUH7</accession>
    <name>A0A2S9GUH7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Isopenicillin N synthase and related dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_3914</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the iron/ascorbate-dependent oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000024">
        <property type="protein sequence ID" value="PRC91369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91369">
        <property type="protein sequence ID" value="PRC91369"/>
        <property type="gene ID" value="S2091_3914"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026992">
        <property type="entry name" value="DIOX_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044861">
        <property type="entry name" value="IPNS-like_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027443">
        <property type="entry name" value="IPNS-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03171">
        <property type="entry name" value="2OG-FeII_Oxy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14226">
        <property type="entry name" value="DIOX_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="3">
        <location>
            <begin position="145"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC91369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="281" mass="31429" checksum="C8FCDD0E30EAA5E7" modified="2018-07-18" version="1">MLIQPIDYRSPTAAQQFAASLHNTGFGVLTHHPLSQALVEQVYAEWLAFFKSEAKHDYTFDPDKLDGYFSTEMSETAKGSSKRDLKEFYHIYPWGRFPSQVSNAARQYYQLGAELAAELLQWVETYSPPAIQARYSMPLSEMIKDSQQTLLRVLHYPPLHGDEDASAMRAAAHGDINLLTILPAATQAGLQVIAKDGQWHDVPSDFGMLIVNIGDMLDEASQGYYPSTVHRVLNPTGAAAKQSRVSLPLFLHPRPEVVLSERHTAQSYLTERLIELGAIKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUS7</accession>
    <name>A0A2S9GUS7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3951</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000024">
        <property type="protein sequence ID" value="PRC91406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91406">
        <property type="protein sequence ID" value="PRC91406"/>
        <property type="gene ID" value="S2091_3951"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="59" mass="6610" checksum="23F4A63D9626D02E" modified="2018-07-18" version="1">MIAGVEVEVEVEVEVEVEVAFDLAFEVAFDLAFEVVFDLPPLLVRPMNLRINGSERFAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUT3</accession>
    <name>A0A2S9GUT3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">EamA-like transporter family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3770</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000022">
        <property type="protein sequence ID" value="PRC91492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91492">
        <property type="protein sequence ID" value="PRC91492"/>
        <property type="gene ID" value="S2091_3770"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="93"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="125"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="152"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="182"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="213"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="245"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="269"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="5"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="152"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="309" mass="33401" checksum="FACDE004DF4607DE" modified="2018-07-18" version="1">MNRIYLRLIGATFLWATVFHVGKFALAEFSPLAIATWRYSIAAIILLAMTLPAIRSNWQQIKSHWPILFILALLGVVGFALFIFYGLRLTSPVNASLIMAFNPALIIVLSSLFNREPVSRQQISGLLLGLCGVLIVVSHASLNALINLSFSKGDLLVGVASLCWAAYCVLPKRYASSIPSAQLSAVTIITAAILMLVMAGFSASDMPQLPRTGMLFVLLFLGLFGTVIPYLWWNQGVQKIGPAKAGVFMNLVPIFASLIGVVLGQQLQASQLAGASLVIIGVLITSIKFNKAGNKVMNKNDQHKLAAFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUU6</accession>
    <name>A0A2S9GUU6_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glucose-6-phosphate isomerase</fullName>
            <shortName evidence="7">GPI</shortName>
            <ecNumber evidence="7">5.3.1.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Phosphoglucose isomerase</fullName>
            <shortName evidence="7">PGI</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Phosphohexose isomerase</fullName>
            <shortName evidence="7">PHI</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">pgi</name>
        <name evidence="9" type="ORF">S2091_3841</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7 8">
            <text>alpha-D-glucose 6-phosphate = beta-D-fructose 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:11816"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="ChEBI" id="CHEBI:58225"/>
            <dbReference type="EC" id="5.3.1.9"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Carbohydrate biosynthesis; gluconeogenesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 7 8">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7 8">Belongs to the GPI family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.9" evidence="7"/>
    <dbReference type="EMBL" id="PUGF01000023">
        <property type="protein sequence ID" value="PRC91426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91426">
        <property type="protein sequence ID" value="PRC91426"/>
        <property type="gene ID" value="S2091_3841"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00181"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00138"/>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097367">
        <property type="term" value="F:carbohydrate derivative binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004347">
        <property type="term" value="F:glucose-6-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd05015">
        <property type="entry name" value="SIS_PGI_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05016">
        <property type="entry name" value="SIS_PGI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00473">
        <property type="entry name" value="G6P_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001672">
        <property type="entry name" value="G6P_Isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023096">
        <property type="entry name" value="G6P_Isomerase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018189">
        <property type="entry name" value="Phosphoglucose_isomerase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046348">
        <property type="entry name" value="SIS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035476">
        <property type="entry name" value="SIS_PGI_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035482">
        <property type="entry name" value="SIS_PGI_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11469">
        <property type="entry name" value="PTHR11469"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00342">
        <property type="entry name" value="PGI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00662">
        <property type="entry name" value="G6PISOMERASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53697">
        <property type="entry name" value="SSF53697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00765">
        <property type="entry name" value="P_GLUCOSE_ISOMERASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00174">
        <property type="entry name" value="P_GLUCOSE_ISOMERASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51463">
        <property type="entry name" value="P_GLUCOSE_ISOMERASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 7 8" id="KW-0312">Gluconeogenesis</keyword>
    <keyword evidence="4 7 8" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="5 7 8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton donor" evidence="7">
        <location>
            <position position="361"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="392"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="512"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC91426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="558" mass="62710" checksum="50DAA7E8B06FB371" modified="2018-07-18" version="1">MRDTTLTPGPRLLERLTWQELVAHHKLIGDLHLRQLFSDDPQRGEHLTAEGAGLYLDYSKNRVTDETLRLLLQLADDCGLPAHIDAMFSGRNINTSEKRAALHIALRAQVGEHIEVDGVDVVPQVYAVLDQMAAFSESVRSGKWLGYTGRVIRNVINIGIGGSDLGPVMAYDALLQYSRRDMCFRFISNVDGTDFVEATRDLDPEETLFIICSKTFKTQETLTNAYSARAWCLSTIKDERAVQRHFVAVSTNTDGVEKFGIDPANMFVFWDWVGGRYSMDSAIGLSTMIAIGEQNYRAMLSGFHAMDMHFRSAPFAQNLPVLMGLLAIWNNNFLGAETVAVLPYEQYLKRFPAYLQQLAMESNGKHVTLDGDPVGVMTGPIYWGEPGTNGQHSFFQLMHQGTRLVPCDFIGFCQPLNPVGRHHDLLMANLFAQTEALAFGKTQEQIATEGTPPWLAPHRMFEGNRPTNTILAERLTPEVLGQLVALYEHSIFTQGAIWQIDSFDQWGVELGKDLAQRIIPELEDVDAPKLEHDSSTKALILRYRRLRDELTHQQTNEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUW5</accession>
    <name>A0A2S9GUW5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3781</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000022">
        <property type="protein sequence ID" value="PRC91503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91503">
        <property type="protein sequence ID" value="PRC91503"/>
        <property type="gene ID" value="S2091_3781"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010710">
        <property type="entry name" value="DUF1289"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35175">
        <property type="entry name" value="PTHR35175"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06945">
        <property type="entry name" value="DUF1289"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="75" mass="8369" checksum="0B2C2F78CCBF346F" modified="2018-07-18" version="1">MNESILQVSLNAQQTNVPPRADTPCVAVCSTTFDEICRGCGRTVVEVATWVVMDEAEKELVWQRILSQGYPRRNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GV14</accession>
    <name>A0A2S9GV14_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DinB family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3774</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DinB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000022">
        <property type="protein sequence ID" value="PRC91496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91496">
        <property type="protein sequence ID" value="PRC91496"/>
        <property type="gene ID" value="S2091_3774"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007837">
        <property type="entry name" value="DinB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034660">
        <property type="entry name" value="DinB/YfiT-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37302">
        <property type="entry name" value="PTHR37302"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05163">
        <property type="entry name" value="DinB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109854">
        <property type="entry name" value="SSF109854"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="167" mass="19318" checksum="40763A6137F42F65" modified="2018-07-18" version="1">MSTSKILISLFNYKSWANEEIFAALKNLNQVDHKNELHSAIRILNHIYVVDRIFNANLQGIKHGFTSTNTVETPSLENLWKDVHETDSWYIKYVSELDQNQLQDDLSFTFVDSDTGKMSREEMLFHLITHGGYHRGAVGRILAQLSIAPPRDVFTKFLHDTEPTRRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GV83</accession>
    <name>A0A2S9GV83_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3739</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000021">
        <property type="protein sequence ID" value="PRC91623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91623">
        <property type="protein sequence ID" value="PRC91623"/>
        <property type="gene ID" value="S2091_3739"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07377">
        <property type="entry name" value="WHTH_GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00392">
        <property type="entry name" value="GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50949">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="2">
        <location>
            <begin position="3"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="441" mass="48404" checksum="AD556DFFF3B7DEBA" modified="2018-07-18" version="1">MAQARYKSIVDGIAIRIRQGDFRPGFQLPTIREVMKEHHIALATASRVYAELEAIGLIVREVGRGTFVRDTSLPRGLGLEQHSIRSGAVDLTFNYPSLPGQAEMLRDGLRYIASSGDLDALLHSAPQGGRPHERQTVAKHIRNRGIRVAGEQILLVNGAQQGLAVTVMGLLKPGDILAIDALTYPGMKALAHTYRLDLESLPHANGAINLDALAALCKKRPVRAIYTMPTMHNPLGYVMSKQDRVRLAKLADQYNFLIIEDGAYAFLAEPAPPPVFTYAPLRTVYVSGLSKSVASGLRIGIIAAPLNLMPALEHAIRVSTWSTPSLMVMLACNWIESGAVDLLEDQKRQDARQRQNLARRILRGCKIVAHPSSYYLWLELPEELRSDQVAADLERVGVLVTTAEPFAVTPNVPHALRLALGSISFDVLDDALHKVRRATSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVE8</accession>
    <name>A0A2S9GVE8_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Electron transfer flavoprotein-ubiquinone oxidoreductase</fullName>
            <shortName evidence="9">ETF-QO</shortName>
            <ecNumber evidence="9">1.5.5.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">S2091_3618</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Accepts electrons from ETF and reduces ubiquinone.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>a ubiquinone + reduced [electron-transfer flavoprotein] = a ubiquinol + H(+) + oxidized [electron-transfer flavoprotein]</text>
            <dbReference type="Rhea" id="RHEA:24052"/>
            <dbReference type="Rhea" id="RHEA-COMP:9565"/>
            <dbReference type="Rhea" id="RHEA-COMP:9566"/>
            <dbReference type="Rhea" id="RHEA-COMP:10685"/>
            <dbReference type="Rhea" id="RHEA-COMP:10686"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16389"/>
            <dbReference type="ChEBI" id="CHEBI:17976"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58307"/>
            <dbReference type="EC" id="1.5.5.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="9">Binds 1 [4Fe-4S] cluster.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.5.5.1" evidence="9"/>
    <dbReference type="EMBL" id="PUGF01000020">
        <property type="protein sequence ID" value="PRC91680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91680">
        <property type="protein sequence ID" value="PRC91680"/>
        <property type="gene ID" value="S2091_3618"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004174">
        <property type="term" value="F:electron-transferring-flavoprotein dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040156">
        <property type="entry name" value="ETF-QO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10617">
        <property type="entry name" value="PTHR10617"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 9" id="KW-0249">Electron transport</keyword>
    <keyword evidence="4 9" id="KW-0274">FAD</keyword>
    <keyword evidence="3 9" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="9" id="KW-0408">Iron</keyword>
    <keyword evidence="7 9" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 9" id="KW-0813">Transport</keyword>
    <keyword evidence="8 9" id="KW-0830">Ubiquinone</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU366068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC91680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="556" mass="60544" checksum="90FDBFFC015C1BC1" modified="2018-07-18" version="1">MTTNFLEKFGPRDTMEYDVVIVGGGPAGLSAAIKLKQLALAQSKEVSVCVLEKGGELGAHILSGAVMDPIAINELFPNWKELGAPLNTEVSEDRFLMLTETGSIKTPNWMLPDCFQNHGNYVISLANVVRWLGQQAESLGVEIFPGFPAAEILYNEDGSVKGVATGNMGVSHDGTASAAFQLGMELHAKYTLFAEGARGHLGKQLMQKFNLNEQCDPQTYGIGIKELWEIDPAKHQAGLVIHTAGWPLASDTYGGSFLYHLENNQVAVGLVVGLSYANPYLSPYEEFQRYKTHPAIRHFFEGAKRISYGARAITAGGLQSLPKLTFPGGALIGCDAGFLNMSRIKGSHAAMKSGMLVAESIFTALASERAHDELSSYSVAFKDSWLHTELHKARNVKPWLAKGLYFGAAMVGIDQILFKGKAPWTLHHQHADHECLRPASEFEPIVYPKPDGKLTFDRLSSVFISNTNHAEDQPIHLTLKNAEVPVGINLAQYAGPEARYCPAGVYEFIKADDGADKLQINAQNCVHCKTCDIKDPTQNIVWVTPEGGGGPNYPNM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVH5</accession>
    <name>A0A2S9GVH5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NHL repeat</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_3484</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000019">
        <property type="protein sequence ID" value="PRC91729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91729">
        <property type="protein sequence ID" value="PRC91729"/>
        <property type="gene ID" value="S2091_3484"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001258">
        <property type="entry name" value="NHL_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01436">
        <property type="entry name" value="NHL"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51125">
        <property type="entry name" value="NHL"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015510035" evidence="3">
        <location>
            <begin position="23"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="repeat" description="NHL" evidence="2">
        <location>
            <begin position="93"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="repeat" description="NHL" evidence="2">
        <location>
            <begin position="157"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="repeat" description="NHL" evidence="2">
        <location>
            <begin position="279"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC91729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="362" mass="38252" checksum="17C89DD5CF25B96D" modified="2018-07-18" version="1">MRKILIALLMIICSTLCNFSLAAAKEGTLIKIGDISFGNGLPVGLASDKIGNIYIADFFKNQILKINRDKTTVVIAGDGKLGYRDGSGKIARFSGPSAIAIDDGGNVIVADSGNNLIRKISKDGIVSTVAGEFEWYKDPSVQDRNGARDGAATKARFNYPQGVAVDSRGNIYVSDSQSQRIRLISPKGIVSTLSGISTWYRIGYVDGTASNAVFYYPEGLAFGSDGFLYVADNNAIRKIAPDGSVSTLAGGQRARIAASKNEPFKYTGGNIDGAPQIAEFAAPVALAIDNQGNIYVADENNKAIRKVAPDGNTTTLLDLSKYYPADTNPPTARSGAPIGITMLPDGSLVICVPGGIYKYSVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVI1</accession>
    <name>A0A2S9GVI1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein involved in formation of curli polymer</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3652</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000020">
        <property type="protein sequence ID" value="PRC91714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91714">
        <property type="protein sequence ID" value="PRC91714"/>
        <property type="gene ID" value="S2091_3652"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030288">
        <property type="term" value="C:outer membrane-bounded periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005534">
        <property type="entry name" value="Curli_assmbl/transp-comp_CsgG"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03783">
        <property type="entry name" value="CsgG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="240" mass="25949" checksum="71289EA8EEBE6EBC" modified="2018-07-18" version="1">MQALIAHCHLEIKLKINKTIPLFASIVLASTLAGCATESSQSLPIQKVISASQPYVGVRTLISVGKFDNRSSYMRGIFSDGVDRLGSQAKTILISHMQQTNRFNVLDRDNMAEMKQEADLKKQTQNIKGADFVVTGDVTEFGRKEVGDQQLFGILGRGKTQVAYAKVTLNIVNIATSEVVYSSQGAGEYSLSNREVIGFGGTASYDSTLNGKVLDLAMREAVNTLVAALDSGAWTPNKPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVJ0</accession>
    <name>A0A2S9GVJ0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3479</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000019">
        <property type="protein sequence ID" value="PRC91724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91724">
        <property type="protein sequence ID" value="PRC91724"/>
        <property type="gene ID" value="S2091_3479"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="149" mass="16800" checksum="3611FEC851EF146C" modified="2018-07-18" version="1">MIAQAEYCWMIGCIGNVGYVYIPASQMIVKADTTEMDFNGAKYKLDQSNKLLKEFGLPSVGTTVELNINATLLAKDEIDSSSVLQEIKQPWFNLDKEQLKVQLHNYDFSENFLGGGLMRSGARFKVLGYVGDYFYGHSRLFALVYIESD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVJ4</accession>
    <name>A0A2S9GVJ4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3485</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000019">
        <property type="protein sequence ID" value="PRC91730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91730">
        <property type="protein sequence ID" value="PRC91730"/>
        <property type="gene ID" value="S2091_3485"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="105" mass="11946" checksum="C65CD46C41273379" modified="2018-07-18" version="1">MTSIDQQHTQQLRPLITHLAVDTIDTYTQARDIVRDFSAIFEVLDHLALTDFSNERIAPILFRAGFCHATERLKFIDEKISEAYKTLDDLKTDSSPAFKTSSDAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVL9</accession>
    <name>A0A2S9GVL9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">GGDEF: diguanylate cyclase (GGDEF) domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_3506</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000019">
        <property type="protein sequence ID" value="PRC91751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91751">
        <property type="protein sequence ID" value="PRC91751"/>
        <property type="gene ID" value="S2091_3506"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013767">
        <property type="entry name" value="PAS_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00989">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="304"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="2">
        <location>
            <begin position="462"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="3">
        <location>
            <begin position="535"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="4">
        <location>
            <begin position="625"/>
            <end position="759"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC91751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="759" mass="84693" checksum="CAB06387065DE3A6" modified="2018-07-18" version="1">MHAKSTLSLWLNSTTRTSLFLQIATPLILIALAIVFQLNSLQASREQQLERTRLSAQDLGATLAASIAGSFQNINLTLLAATDHIRQQQSKGFDGRELNAELLELQSRVPSLILLSATNASGDVIFGIKGNRSEKVNVADREYFLQLMINPDAGMVISEPVMGRYSKKWVLICARRFNLPDGQFGGIVYGSIALDGMTERLSGKEMKLNENDAFVLRDNHMNVIVRYAHGKQDMQIMGSKINSPTLEALDKAGAQSGSYITNSVLDHVERSFYFQRISGQAMSLIVGLSIDDALSNWQLEVKKAWIVTGFFASIILLSFYLIYREQIRKLNVIGDLEATTDKLTEVLKFNEAILLNSPLPIGVYTVDGQCVKVNEALTQLVGASSEVLLSKNFRHITTWQTSGLLDGCLAALTNNSLQKCEVRMMTAFGKDIIAECRILPTQLHDATHLLIQFVDLTEIKRINSMLENILRSMKEGVHVVNEKGIILLENDASLVMLGWQDDNILGRMAHATIHHHHADRSDFPVEDCPIYATLQDGQVRHIDNDVFWKRDGSCFPVEYTVSPILNLQGGGHAATVVFRDITTRKRLEDELREQAFHDALTGLPNRRLLMDRIGQAIRVNKRHNSHAAVLFLDLNKFKVLNDTHGHNAGDQLLIEVAKRLTHVVRESDTVARLGGDEFVVLLMELNSQFEQAQEYAEFVADKIHNVLNTEYVFGEIMHQGSASIGIKLFFNEDDPDTILKAADAAMYEAKNRNNAVNSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVT5</accession>
    <name>A0A2S9GVT5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Flagellar biosynthesis/type III secretory pathway chaperone</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3389</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Required for the efficient initiation of filament assembly.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FlgN family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000018">
        <property type="protein sequence ID" value="PRC91833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91833">
        <property type="protein sequence ID" value="PRC91833"/>
        <property type="gene ID" value="S2091_3389"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044780">
        <property type="term" value="P:bacterial-type flagellum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007809">
        <property type="entry name" value="FlgN-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036679">
        <property type="entry name" value="FlgN-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05130">
        <property type="entry name" value="FlgN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140566">
        <property type="entry name" value="SSF140566"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0966">Cell projection</keyword>
    <keyword evidence="3" id="KW-0969">Cilium</keyword>
    <keyword evidence="3" id="KW-0282">Flagellum</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="158" mass="17760" checksum="19006C100210A90D" modified="2018-07-18" version="1">MNTLLFCIQNETDAMTALVEVLGQEQTALTQAPSLPLMEEINAVMQRKNQLIASISQLGHTRKNELTRLGFKHPETSMPEWLQDQAQVECWAKLMKLTRKAKELNRVNGLLITKHLIRNQSTLQVLYQNHGSTSTPSLYGANGQSNTQRSTVRGFIAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVX4</accession>
    <name>A0A2S9GVX4_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_3431</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="PUGF01000018">
        <property type="protein sequence ID" value="PRC91875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91875">
        <property type="protein sequence ID" value="PRC91875"/>
        <property type="gene ID" value="S2091_3431"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013655">
        <property type="entry name" value="PAS_fold_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08447">
        <property type="entry name" value="PAS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="41"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="6">
        <location>
            <begin position="130"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="7">
        <location>
            <begin position="206"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="5">
        <location>
            <begin position="262"/>
            <end position="480"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC91875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="492" mass="54971" checksum="37C0BFE261869AC8" modified="2018-07-18" version="1">MIDPQDNSPRIALNFRLALATLCVLAIGFVAYVFITEVTTAQLRIITILFGLLIVYLCWSMQQHWRAILGGTVHELHEQIERLGSSDFSSPISIAPGIDKSVMSALAEAQSKLRAVYTQHAHDELILKEREERARLAIAGSNDGLWDRDIEQDTIYYSPRWKSILGYTDAELANTVATWVSHIHPEDADWVISQALSCDAKNTDRFHYEYRLRRKDGQYIWVLDRGLIARNLAGKPRRLVGILTDISEQKLAEKMKNEFISTISHGLRTPLTSIHGSLQLLVAGVMGDLPYKAHDMVKLASKNSQLLINLVDEILDMEKLMSGMMIFHKDEIELVKIIEQSIMLNAGYATSFGVRYMLAPHEGPCRVISDTNRLMQILANLLSNAAKFSRQGGIVTVRIVPADGFARVEIEDHGEGIPLAFRSKIFGEFTQADRSNTRSDGAGLGLNIAKKMVGKMGGEIGYMTEVNQGTTFWFTVPMIDNYLVRSSGYVGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVX9</accession>
    <name>A0A2S9GVX9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Bacterial extracellular solute-binding protein, family 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3435</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000018">
        <property type="protein sequence ID" value="PRC91879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91879">
        <property type="protein sequence ID" value="PRC91879"/>
        <property type="gene ID" value="S2091_3435"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001638">
        <property type="entry name" value="Solute-binding_3/MltF_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00497">
        <property type="entry name" value="SBP_bac_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="PBPb" evidence="2">
        <location>
            <begin position="36"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="262" mass="29626" checksum="C97AF5F1419654F3" modified="2018-07-18" version="1">MLANSLLSVMCHAGAVTNDAQAQDQLPRVIEMCDGIDEWPPYMYFKRINGEKSSEVVGYAFDYVSRILARKGIKATIKLIPWNRCVAEVESGKYAMLLDASNSEERDRKFFVSRTYYEVHLVYFYDLSRPKPQINSVADLKKFRLCGVLGYNYAPFLLEPENIDTGADGYDKVMAKLKLNRCDAVPDRLEVAIGFKTIGELDFIGKNIAYDFIPGVKSLSYHMLISRKLPYSHKLIELIDEGIVEINAHSGAADLAEKYGLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWA8</accession>
    <name>A0A2S9GWA8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Electron transfer flavoprotein alpha subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_3320</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ETF alpha-subunit/FixB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000017">
        <property type="protein sequence ID" value="PRC91978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91978">
        <property type="protein sequence ID" value="PRC91978"/>
        <property type="gene ID" value="S2091_3320"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014730">
        <property type="entry name" value="ETF_a/b_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001308">
        <property type="entry name" value="ETF_a/FixB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014731">
        <property type="entry name" value="ETF_asu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43153">
        <property type="entry name" value="PTHR43153"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01012">
        <property type="entry name" value="ETF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00766">
        <property type="entry name" value="ETF_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000089">
        <property type="entry name" value="Electra_flavoP_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00893">
        <property type="entry name" value="ETF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="SSF52467"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0249">Electron transport</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ETF" evidence="3">
        <location>
            <begin position="59"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC91978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="374" mass="39845" checksum="FA8EB6883781D76A" modified="2018-07-18" version="1">MQPTSATRRINPRRPYVISANGLKRIILGSDQGTRDLQLTRHTAVAKTFRTTQTATRNLLVLLHSDNGMLDAHGKEVIAAAALLADLQTAVVVAVLGGTGEDLGAFGADVVITLSQLDAMQFRPELSLALVAKLIAEYQPQHLFLADRNADGDLGRRLAARCKYSIATDVVEVGGDYALRLVPGGKYARCALPQIVLLARHAADVNLPFIGQGRSVMTHECTEVFPSVVTDLGLETSNPDSISLEEADFIVSAGNGMNDMEAFNALATLLGASVGASRVAVDDGRFSRDKQVGATGKTVQSSVYLALGISGAVQHLQGIKECRHVIAVNLDASAPIAKRANLMVVEDAQALMRALMSQVQQAKQEKMTTQTSYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWC3</accession>
    <name>A0A2S9GWC3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">YecA family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3369</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000017">
        <property type="protein sequence ID" value="PRC92027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92027">
        <property type="protein sequence ID" value="PRC92027"/>
        <property type="gene ID" value="S2091_3369"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.740">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004027">
        <property type="entry name" value="SEC_C_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011978">
        <property type="entry name" value="UPF0149"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036255">
        <property type="entry name" value="YgfB-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02810">
        <property type="entry name" value="SEC-C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03695">
        <property type="entry name" value="UPF0149"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101327">
        <property type="entry name" value="SSF101327"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02292">
        <property type="entry name" value="ygfB_yecA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="232" mass="26223" checksum="57D623D5EE0E6910" modified="2018-07-18" version="1">MHLDQPLSDKEFDELDNFLMSDAVGDEGMTMDALHGYLTAITIGPEFIPLSEWLPNVWGLEGEAEPKFDSEKHSERIISLIARFMNEVIITFEVAPKEFEPLFCVYELNGKEIIDGEAWAWGFWEGMQLRADAWETIKSSSLEPLLRPIYLLGADEISEEEMKLVDEPVKCHKLAIEVEAAIPHLYQYWLPLRTSGVSTIKRDTPKQGRNDVCNCGSGKKYKNCCGAGPTVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWC5</accession>
    <name>A0A2S9GWC5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">FeS assembly protein IscX</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3343</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000017">
        <property type="protein sequence ID" value="PRC92001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92001">
        <property type="protein sequence ID" value="PRC92001"/>
        <property type="gene ID" value="S2091_3343"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.600">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007479">
        <property type="entry name" value="ISC_FeS_clus_asmbl_IscsX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036762">
        <property type="entry name" value="IscX-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37532">
        <property type="entry name" value="PTHR37532"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04384">
        <property type="entry name" value="Fe-S_assembly"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039003">
        <property type="entry name" value="IscX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140319">
        <property type="entry name" value="SSF140319"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03412">
        <property type="entry name" value="iscX_yfhJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="67" mass="7958" checksum="BD080A1D15AFA794" modified="2018-07-18" version="1">MKWTDSRAIAIELAEKHPDIDPRQIRFMELREWVLALDSFDDVPEHCGEKILEAIQLMWMDEADEDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWD3</accession>
    <name>A0A2S9GWD3_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 9">Argininosuccinate synthase</fullName>
            <ecNumber evidence="2 9">6.3.4.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8 9">Citrulline--aspartate ligase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">argG</name>
        <name evidence="10" type="ORF">S2091_3362</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ATP + L-aspartate + L-citrulline = 2-(N(omega)-L-arginino)succinate + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10932"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57472"/>
            <dbReference type="ChEBI" id="CHEBI:57743"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.4.5"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 9">Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 2/3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the argininosuccinate synthase family. Type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.5" evidence="2 9"/>
    <dbReference type="EMBL" id="PUGF01000017">
        <property type="protein sequence ID" value="PRC92020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92020">
        <property type="protein sequence ID" value="PRC92020"/>
        <property type="gene ID" value="S2091_3362"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00068">
        <property type="reaction ID" value="UER00113"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004055">
        <property type="term" value="F:argininosuccinate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006526">
        <property type="term" value="P:arginine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01999">
        <property type="entry name" value="Argininosuccinate_Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00005">
        <property type="entry name" value="Arg_succ_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001518">
        <property type="entry name" value="Arginosuc_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018223">
        <property type="entry name" value="Arginosuc_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023434">
        <property type="entry name" value="Arginosuc_synth_type_1_subfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024074">
        <property type="entry name" value="AS_cat/multimer_dom_body"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11587">
        <property type="entry name" value="PTHR11587"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00764">
        <property type="entry name" value="Arginosuc_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69864">
        <property type="entry name" value="SSF69864"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00032">
        <property type="entry name" value="argG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00564">
        <property type="entry name" value="ARGININOSUCCIN_SYN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00565">
        <property type="entry name" value="ARGININOSUCCIN_SYN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="3 9" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="7 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="6 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="10"/>
            <end position="18"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="37"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="90"/>
        </location>
        <ligand>
            <name>L-citrulline</name>
            <dbReference type="ChEBI" id="CHEBI:57743"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="95"/>
        </location>
        <ligand>
            <name>L-citrulline</name>
            <dbReference type="ChEBI" id="CHEBI:57743"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="120"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="122"/>
        </location>
        <ligand>
            <name>L-aspartate</name>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="126"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="127"/>
        </location>
        <ligand>
            <name>L-aspartate</name>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="130"/>
        </location>
        <ligand>
            <name>L-citrulline</name>
            <dbReference type="ChEBI" id="CHEBI:57743"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="182"/>
        </location>
        <ligand>
            <name>L-citrulline</name>
            <dbReference type="ChEBI" id="CHEBI:57743"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="191"/>
        </location>
        <ligand>
            <name>L-citrulline</name>
            <dbReference type="ChEBI" id="CHEBI:57743"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="267"/>
        </location>
        <ligand>
            <name>L-citrulline</name>
            <dbReference type="ChEBI" id="CHEBI:57743"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="279"/>
        </location>
        <ligand>
            <name>L-citrulline</name>
            <dbReference type="ChEBI" id="CHEBI:57743"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00029916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC92020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="409" mass="45953" checksum="3ED3F67B6235029B" modified="2018-07-18" version="1">MSDINKVVLAYSGGLDTSVILKWLQDNYKCEIITFTADLGQGEELEPARQKALKFGIKPENIYIDDLREEFVRDFVFPMFRANTVYEGEYLLGTSIARPLIAKRLIDIAKATGADTISHGATGKGNDQVRFELGAYALMPNVKVIAPWREWDLLSREKLLKYAQDAGIEIDMKHKNGGAPYSMDANLLHISFEGRHLENPSAEAEESMWRWTVSPEAAPDQAEFLDVEFEHGDIVALNGVRMSPATVLTELNRLGGKHGIGRLDLVENRYVGMKSRGCYETPGGTIMLRAHRAIESITLDREVAHLKDDLMPRYASLIYNGYWWAPERIALQTLIDHTQQCVNGWVRLKLYKGNVTTMSRDSKTDSLFDMTIATFDEDGGAYNQADAGGFIKLNALRMRIAANARARRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWX2</accession>
    <name>A0A2S9GWX2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Negative regulator of sigma E activity</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3135</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92219">
        <property type="protein sequence ID" value="PRC92219"/>
        <property type="gene ID" value="S2091_3135"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016989">
        <property type="term" value="F:sigma factor antagonist activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16328">
        <property type="entry name" value="RseA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005572">
        <property type="entry name" value="Anti-sigma_E_RseA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036147">
        <property type="entry name" value="Anti-sigma_E_RseA_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03872">
        <property type="entry name" value="RseA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89069">
        <property type="entry name" value="SSF89069"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="101"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="RseA_N" evidence="2">
        <location>
            <begin position="13"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="207" mass="22556" checksum="B30F023F7B1E96D7" modified="2018-07-18" version="1">MNTNMQNEQNRQSQISALVDGEQADHELSAILATLRTQEHKDDWDIYHKIGDILNSEELSVSISDGFSARMAASLAAEPIYLGLKPLTPKTKTFSQVSTKVAYAMAAMFAFALILVPRFAGQEGAETSAPYYAGQFAAVNSSSMNGAEAKKELAALSASHTTSYESKSHMLRDPQIDSYLAAHQRYSNSTYSAVEYETSPTNQEAGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GX57</accession>
    <name>A0A2S9GX57_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2958</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92299">
        <property type="protein sequence ID" value="PRC92299"/>
        <property type="gene ID" value="S2091_2958"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007896">
        <property type="entry name" value="BTP_bacteria"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05232">
        <property type="entry name" value="BTP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="79"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="113"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="domain" description="BTP" evidence="2">
        <location>
            <begin position="6"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="domain" description="BTP" evidence="2">
        <location>
            <begin position="73"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="144" mass="16876" checksum="B0A177ED36EE5952" modified="2018-07-18" version="1">MTTRKHWLERVFHAFLFELLALIICVPLLVWGLGLEVVHAGALTLIISLVAMVWNMIFNAIFDYFERRYHWQRTTKIRLLHGISFEAGLILAVVPLIAWWADISLLEAFVLDIGLLMFFLPYTIIYNWAYDRLRAAFYQQNAAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GX87</accession>
    <name>A0A2S9GX87_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Helix-turn-helix domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2994</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92335">
        <property type="protein sequence ID" value="PRC92335"/>
        <property type="gene ID" value="S2091_2994"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010921">
        <property type="entry name" value="Trp_repressor/repl_initiator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48295">
        <property type="entry name" value="SSF48295"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="107"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="175" mass="20498" checksum="FB1E510996B3C09F" modified="2018-07-18" version="1">MSKYTKQFKLTVVKRYLDSSMGYVAVAQQYGIDRSFVQKWSKQYALHGEAGLDKKFSHYNAEFKLSVLQSMWDKQLSYRETAILFDIRNLNILSNWERSYHSEGIQALTPRTRGRPKAMSPPKKVQPQPAKTDESRSREELLEEVNYLRMENAYLKKLKALVQEQALEASLKKRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXF6</accession>
    <name>A0A2S9GXF6_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Phospho-2-dehydro-3-deoxyheptonate aldolase</fullName>
            <ecNumber evidence="5">2.5.1.54</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_2765</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 5">Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>D-erythrose 4-phosphate + H2O + phosphoenolpyruvate = 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:14717"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16897"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58394"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="EC" id="2.5.1.54"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 5">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 1/7.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 5">Belongs to the class-I DAHP synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.54" evidence="5"/>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92390">
        <property type="protein sequence ID" value="PRC92390"/>
        <property type="gene ID" value="S2091_2765"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00053">
        <property type="reaction ID" value="UER00084"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003849">
        <property type="term" value="F:3-deoxy-7-phosphoheptulonate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:cellular amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009423">
        <property type="term" value="P:chorismate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006218">
        <property type="entry name" value="DAHP1/KDSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006219">
        <property type="entry name" value="DHAP_synth_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21225">
        <property type="entry name" value="PTHR21225"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00793">
        <property type="entry name" value="DAHP_synth_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001361">
        <property type="entry name" value="DAHP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00034">
        <property type="entry name" value="aroFGH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DAHP_synth_1" evidence="6">
        <location>
            <begin position="40"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR001361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC92390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="353" mass="38527" checksum="FEF830D261C0D553" modified="2018-07-18" version="1">MLRTDDLRIREMKELVPPSHLIREFACTDLASNTVANSRTALHRILHGQDDRVMVVIGPCSIHDTKAAMEYAQRLAQERVRFAGELEIVMRVYFEKPRTTVGWKGLINDPYMDNSFRINDGLRIARELLLNINQLGLPAGTEYLDVISPQYIADLISWGAIGARTTESQVHRELASGLSCPVGFKNGTDGNIKIAIDAMKAASQPHHFLSVTKGGHSAIVSTNGNEDCHVILRGGKTPNFDAASVDLACKEIAGSGIASRLMIDASHANSSKNPQNQIPVCANIAEQIAGGDRRIVGVMIESNLVAGRQDLIAGRELVYGQSVTDGCIHWEDSLQVLEGLAAAVKQRRLKDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXK8</accession>
    <name>A0A2S9GXK8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2824</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92449">
        <property type="protein sequence ID" value="PRC92449"/>
        <property type="gene ID" value="S2091_2824"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="79"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="85"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="169" mass="18584" checksum="7BD21B13E92BCDC3" modified="2018-07-18" version="1">MATIIASRFQLKEQAELVVEQLIQVGFAAGKVTSFYVNPAGQHDAYPIGGDRYQSPGMTQFGKNFAVVEAVIGVSAPKENHMGNHPYQRTGQASSEHATVADNSVHPDDITPIRKAGMLVAVELEDQNFQDRAISFLKRLGAENIEKLEGEIIEGEWHDFDPLSEPSYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXT8</accession>
    <name>A0A2S9GXT8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Peptidase family M48</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_2904</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92529">
        <property type="protein sequence ID" value="PRC92529"/>
        <property type="gene ID" value="S2091_2904"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001915">
        <property type="entry name" value="Peptidase_M48"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01435">
        <property type="entry name" value="Peptidase_M48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="28"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="67"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M48" evidence="8">
        <location>
            <begin position="156"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC92529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="519" mass="58925" checksum="5301F9AA4820A481" modified="2018-07-18" version="1">MEMDRFKSMVTRLEQESAATPTRYRLKVIMLTLVGFGILALILAAVGLGLVLVVGFAAAMVFTGGAALILLLKLGKLLILLALPFWFTLKSSVQALFIRMPAPTGREINRTEAPQLFAALDNMRSQMDGPRVHHVLLINDVNAAVVQRPALGLFGWPRNYLLLGLPLLEYMTPDEALAVVAHEYGHLAGSHGRFSAFIYRLRHTWSTVEAYISHFQGWLSRLISPMVRWYASYFNAYTFVLARADEYRADAASAELVGSHNATRALKRVNIIAPRFRQYLENTFKQVNENSTPPNDLLQRWASSTSIAPEETQMVRWLEDALDKEGHFADTHPTLRKRLVSIANKEEELLTLPPTILEEPASSVWFAQSLESLRIELQEQWAKQVAPSWGTRHIEIHKQQMRLQELQSMPHRDTERQFEMLNLLMRLEPETDIRTAWADFNAANTNHALGLYFEGIARLNKGEQEGLALLDLSMQLDPQATKPACERAYSFLVERKSVDMAESYAVRWRERDALEKKVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXV0</accession>
    <name>A0A2S9GXV0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">N-acetylglutamate synthase and related acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2861</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92486">
        <property type="protein sequence ID" value="PRC92486"/>
        <property type="gene ID" value="S2091_2861"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13508">
        <property type="entry name" value="Acetyltransf_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="149" mass="16953" checksum="89F157006D5FBF4A" modified="2018-07-18" version="1">MTELNMLVRKIFPEELAWANEQYSEINFKLSTESDLIAIAEINGVKAGLGRLCAVDNKAGELGGMFVLPDFRGHAIAANIVDFLLKNSNYSTLYCLAFAHLEVFYKRFGFLPVDETKSVPKEVTDKFLWCRDTYDSSVLLMCREEFFTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GY29</accession>
    <name>A0A2S9GY29_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ASCH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2678</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92623">
        <property type="protein sequence ID" value="PRC92623"/>
        <property type="gene ID" value="S2091_2678"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007374">
        <property type="entry name" value="ASCH_domain"/>
    </dbReference>
    <dbReference type="SMART" id="SM01022">
        <property type="entry name" value="ASCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ASCH" evidence="1">
        <location>
            <begin position="6"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="98" mass="11553" checksum="DEE06080EAB5CCA7" modified="2018-07-18" version="1">MTSLYLNLKGEYFDQIKSGEKTHEFRLASTWKKRLEGKAFDLIVIRRGYPKAGDKSKELIRVWHGYELKQITHPHFGNDPVLVYAIDVTVPYFFNLYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYA3</accession>
    <name>A0A2S9GYA3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2735</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92680">
        <property type="protein sequence ID" value="PRC92680"/>
        <property type="gene ID" value="S2091_2735"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="488" mass="51990" checksum="FB4FFC6650BBDB43" modified="2018-07-18" version="1">MTDAQFQAWLTSPASIPIVLIEAHVNSGGVETVRYLSTDMYNTGAADTPANTCYQPRLTGALTFTEQVVIDNSAGVSSSTIELENSDGALDLWLLDIWNNRQIIAYIGDPRWARSDFRVIFNGIIVDMDCTTRDKPIFNLADQLQLLNTPVTATLLGGTTPNSTQLIPLCFGECHNVTPLLTNPATLEYAVHNGQVANIFEVRDNGVPITANITNATGRFTLNAPPVGTITASVQGDAPAGVYTNTIAGIVQRLVTGFGTNPFATGNLDSVNFSAFATANPQPVGIYLSSSTNVLDACAQLASSVGAQLVMARTGLLQLIQIALPAIGTPTVITQNQIIEQTLMPTARTDVAAGVMLGFCLNYTVQANLLTNLPVGDADMFALDYMIVNMVDAPTQAMYKMTAAPAQQNTLLLVQSDATSEATRRLNLWKKPHITYQFEGTTSLLALVLGQAATIINPRFGMSAGSTGMVISLAPDWTSGRVVVEVLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYA7</accession>
    <name>A0A2S9GYA7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2743</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92688">
        <property type="protein sequence ID" value="PRC92688"/>
        <property type="gene ID" value="S2091_2743"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="143" mass="16893" checksum="1C8A88D87AAA16B9" modified="2018-07-18" version="1">MQTVKNEHEIHETITIDVFYPDHPPRTESKVFKATKKHWHQLGAVCGVCKTKEKVEIHHKFIEWADSEGTDWDKVRLEHPDFDWASFKDDPDFIDSVYNTEPLCEKHHRGPAPHGKHFTPEPIWNMQKYQRADFVYSPDEVAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYA8</accession>
    <name>A0A2S9GYA8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">YD repeat (Two copies)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2759</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92704">
        <property type="protein sequence ID" value="PRC92704"/>
        <property type="gene ID" value="S2091_2759"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045351">
        <property type="entry name" value="DUF6531"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031325">
        <property type="entry name" value="RHS_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006530">
        <property type="entry name" value="YD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20148">
        <property type="entry name" value="DUF6531"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05593">
        <property type="entry name" value="RHS_repeat"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01643">
        <property type="entry name" value="YD_repeat_2x"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015435512" evidence="1">
        <location>
            <begin position="20"/>
            <end position="856"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6531" evidence="2">
        <location>
            <begin position="165"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="856" mass="91110" checksum="7C54C94E1A9AD1A3" modified="2018-07-18" version="1">MKRFILFILLSFFMFSSFAQRGAASVATATVYNPVSYNINGVNVPASYGSFIADCSPDPKTTFGSPFTTITITEHTPTVTEYWCSSSYGFYAFLDVMQTCPPSSGTIFDTTNSSCICPSTGSTTSFNDYYSDVQKCVLTNQVPAPPRAKPINSGCPVCDKAKSVGDPINVGTGNSYQTQTDLAVVAPFSGLSISRTYNSLPTNPDASTIRSFGTRWTQPYDARVTPIGWETPPNMVTSTIPVICWQRTDTGYIWCEYPKVPVWQVVTVTRGDGKGLYFTAPAATAGSQIWTADQGVTGQLTSTVASDGITPTSFTFTDTDNHTETFDGNGLLLKLTAQSGSTQQLTYSTGTTNDSSVSRYPATAPICPHVQAGAAVASGTLLCVTDNWGRQLQFEHDQPGVNESVGRITLAIDPNNHVTQYGYDGPSAGCMTVNGQQTYACLASNLTSITYPDGKTKTLYYNEAAQINGGTVCPGSAPVGNGFGYLLNTLTGIVDENGTRSVSWTFDCNGIATSSQLGAGVDSYQIAVGAADVNGNSTSVVTSPLGTQTTYGFTAVNGLVVGNAVAQPAGSGSATATASSTFDANGNLTSHTDFNGHITNYTYDANRNLELIRTEAMGTTQARTITTSWNPTYRLPAQVAEPLRMTTYTYDTNGNLLTKTQQATTDVNGVQGVSATVTGTPRKWTYTYNSVGQVLTITGPRTDVTDLTQFAYDTYGNLSSVTNAAGQVTTLSNYDLNGHVGSITDPNGLTTTYAYSPRGWLTSQSRGSEVTSYNYDGAGQLLSVTFPNQAKLTYTYDTAHRLTNIADNLGNTVNYTLDAMGNRTLEQVNDTSGNLARQISRVVDALNRLQQITGAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYR1</accession>
    <name>A0A2S9GYR1_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Type II secretion system protein E</fullName>
            <shortName evidence="3">T2SS protein E</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Type II traffic warden ATPase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_2284</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">ATPase component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm. Acts as a molecular motor to provide the energy that is required for assembly of the pseudopilus and the extrusion of substrates generated in the cytoplasm.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the GSP E family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92867">
        <property type="protein sequence ID" value="PRC92867"/>
        <property type="gene ID" value="S2091_2284"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015627">
        <property type="term" value="C:type II protein secretion system complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015628">
        <property type="term" value="P:protein secretion by the type II secretion system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001482">
        <property type="entry name" value="T2SS/T4SS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037257">
        <property type="entry name" value="T2SS_E_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013369">
        <property type="entry name" value="T2SS_GspE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00437">
        <property type="entry name" value="T2SSE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160246">
        <property type="entry name" value="SSF160246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02533">
        <property type="entry name" value="type_II_gspE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00662">
        <property type="entry name" value="T2SP_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0653">Protein transport</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="T2SP_E" evidence="4">
        <location>
            <begin position="315"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU366070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS00662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC92867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="478" mass="52384" checksum="DD65D40613274361" modified="2018-07-18" version="1">MAPITIAQANLLPYVFARECAILAAWGEPELLYVWASERTAPTAIAEVGRRYGRIKLVQISHIDLEQAIDRAYAGSGGDAAQVVDEVESDLDLAKLMSDLPAIEDLLESADDAPVIRMINALLTQALRETASDIHIEPFEQISVVRFRIDGTLRDVVRPKKAIHAALISRIKIMAQLDIAEKRLPQDGRIALRIGGRSVDVRVSTLPTGHGERAVLRLLDKEAGKLDLINLGMSDAMSPKFNKLINQPHGIVLVTGPTGSGKTTTLYAALSRLNASTTNILTVEDPIEYELPGIGQTQVNARIEMTFAKALRAILRQDPDVIMIGEIRDLETAQIAVQASLTGHLVLATLHTNDSAAAVTRLLDMGIEPFLLSSSLLGVVAQRLVRKLCTHCKRQEATDWHPVGCDKCAHTGYQGRVGVYELLTTTEQIRAQIHQKASEAEIRTVAKSDGMLSMREDGERWINEGVTSREELLRVTKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYU1</accession>
    <name>A0A2S9GYU1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Gram-negative porin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_2298</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92881">
        <property type="protein sequence ID" value="PRC92881"/>
        <property type="gene ID" value="S2091_2298"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046930">
        <property type="term" value="C:pore complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015288">
        <property type="term" value="F:porin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006811">
        <property type="term" value="P:ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00342">
        <property type="entry name" value="gram_neg_porins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033900">
        <property type="entry name" value="Gram_neg_porin_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023614">
        <property type="entry name" value="Porin_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13609">
        <property type="entry name" value="Porin_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0406">Ion transport</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0626">Porin</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1134">Transmembrane beta strand</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Porin_4" evidence="4">
        <location>
            <begin position="16"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC92881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="353" mass="38316" checksum="6841CB9E5694A909" modified="2018-07-18" version="1">MKSSFYKPSLTVFTSVLMGFNYNASAQSNITVFGAIDTALRYSTNQNGDGGNLAEVGSGAANVNRFGVSGEEDLGAGLKANFMLDAGFNSATGESGDGGKLFSRQAWVGLSGTYGAVTAGRQFSPVYNAQWAIEPFGWANLTESGFIYDNYAGDIHWDNSLMYSGTYGDFTGVLMVGMGEKAGDSKAWRNVGGSLAYASGLFTAIAAYQEVRNTDAVIANKVWNVGGSYNIKPVQLFFGYLNYRSDLALQKNHVFDLGFIYSMTPKIDLIGAYYHDRQRAEDGRKNTVAGMLKYSFTPRTAIYIQTDYSKIDAGYVNNISDQYAFPSTRDADNNLTSFVSSRASVSIGLRHIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYW7</accession>
    <name>A0A2S9GYW7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">GGDEF: diguanylate cyclase (GGDEF) domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_2328</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92911">
        <property type="protein sequence ID" value="PRC92911"/>
        <property type="gene ID" value="S2091_2328"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015579396" evidence="4">
        <location>
            <begin position="23"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="385"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="103"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="5">
        <location>
            <begin position="444"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="354"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC92911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="599" mass="66902" checksum="EBBBB05DBACB3E8B" modified="2018-07-18" version="1">MRFLIALTLLISLLGCHFSAYATSDIDIEQELTRVGELLKSDPQQARAALAVLESAQAHFSPPQVIHLLILKSSVLGFFNQHHERVAYLNGFIDRVQDPNIKSKFLYHLSTSYAALGEYERALDAMNTSIALLPRVTDTIAKITSLQAAVTLLNSLYAYSEALSYANRMYDLPLLNQDLSAKCIASADRVEIYMMLKQRSLAREQMREAVDLCDKNGRTYVSQIVHSFAAIDLIDNQEYQSGINAGLTALRAFPSSMHTDYVSRLEDGLARAYLLTGRLVAAEQYGHLAYQHATEQKLAQETEKSLETLAQIKRAQAQYSAALGYAEKALAQKNALLDEQFQKNVAYQRVKFSMQDQSNQVALLEKQNKILAIEKQLEKKNSQNLWLIIALVMVVATALGLYLWKVILQKNFFRRTTQIDGLTRISTRGHFMTSAEEVVSVRNKVVSLILFDMDFFKRINDSFGHPVGDWVLIKVCQTVSAELRDGDLFGRLGGEEFAICLPNTDVEMAWQLAQRCRAAIAAIDAEPCGFQFPLSASFGIACIDQNDNRQFSTLLEAADKALYQAKSEGRNCVVVSNLMGTADIAHYQAKSDERNCVSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZB0</accession>
    <name>A0A2S9GZB0_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Aldehyde dehydrogenase (NAD(+))</fullName>
            <ecNumber evidence="3">1.2.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_2124</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="1">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.3" evidence="3"/>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93038">
        <property type="protein sequence ID" value="PRC93038"/>
        <property type="gene ID" value="S2091_2124"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004029">
        <property type="term" value="F:aldehyde dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043878">
        <property type="term" value="F:glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044638">
        <property type="entry name" value="ALDH7A1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43521">
        <property type="entry name" value="PTHR43521"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldedh" evidence="6">
        <location>
            <begin position="21"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC93038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="501" mass="53666" checksum="382904EB8C766D78" modified="2018-07-18" version="1">MNNINDLLKELGVDLAPYSGNQIHSVSPINGLILASLRADNSAHVASKIGSAHAAYLQWREIPAPRRGELVRLFGDELRTHKAALGQLVTLEAGKILQEGLGEVQEMIDICDFAVGLSRQLYGLTIASERPGHRMMEQWHPVGVVGVISAFNFPVAVWAWNAALAFVCGNSVTWKPSEKTPLTAIAIHSLFMKAVARFGSDAPAGLAELIIGNSDAGIAMVDDRRVPVVSATGSTRMGRDVAQRCATRLSRTILELGGNNAMTVAPSADIEMALRGITFSAVGTAGQRCTTLRRLFVHDSVYDTVVPRLKKIYAGLPIGSPLEKSTLIGPLIDANAFSAMQEALNTAKSEKGKVFGGERAKVEGCTDGYYVHPALVEMPTQTASMHHETFAPILYIVRYTDLDQAIAWNNEVPQGLSSSIFTTDVREAEKFMCDSGSDCGIANVNIGPSGAEIGGAFGGEKDTGGGRESGSDAWKAYMRRSTNTINYSHSLPLAQGISFDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZG0</accession>
    <name>A0A2S9GZG0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2423</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC93006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93006">
        <property type="protein sequence ID" value="PRC93006"/>
        <property type="gene ID" value="S2091_2423"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="229" mass="26069" checksum="0A6A9FE5BBB69144" modified="2018-07-18" version="1">MKNNFYYTALLLMPTLATQAQTKPNDSEIFPEPFIGVQVVPSNKMMSPTNSISNKQLKENGYIHSESENPGKLMAIKSRLPKNRVTLTDDPHYYYLRKNIEDIKLTFSYHPISQGELLGYAPVGTQINQAWTGIREFFKNKEFGLCSLTKYHIVDSKMGVRINADSVAYEVNSHLTTLNVEGSNESGFMYTVNWADSVFWNQLECAQDTFDKSIIHRMSAYASKIATQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZN0</accession>
    <name>A0A2S9GZN0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Truncated hemoglobin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_2253</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93167">
        <property type="protein sequence ID" value="PRC93167"/>
        <property type="gene ID" value="S2091_2253"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019825">
        <property type="term" value="F:oxygen binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015671">
        <property type="term" value="P:oxygen transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.490.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009050">
        <property type="entry name" value="Globin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012292">
        <property type="entry name" value="Globin/Proto"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019795">
        <property type="entry name" value="Globin_bac-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001486">
        <property type="entry name" value="Hemoglobin_trunc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01152">
        <property type="entry name" value="Bac_globin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46458">
        <property type="entry name" value="SSF46458"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01213">
        <property type="entry name" value="GLOBIN_FAM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC93167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="132" mass="15576" checksum="E2E2BA717E0616E1" modified="2018-07-18" version="1">MTQHSDSSTLYEQIGGAEKLRELVDRFYDLMSLEADFNGILKLHPTPLSGSRDKLFWFLSGWMGGPDLYIEQFGHPRLRARHLPYQIGISERNQWLICMCTAMQDMQIEEKLRDRLLQSFYETADWMRNREG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H057</accession>
    <name>A0A2S9H057_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_2099</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93361">
        <property type="protein sequence ID" value="PRC93361"/>
        <property type="gene ID" value="S2091_2099"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PAS" evidence="6">
        <location>
            <begin position="44"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="7">
        <location>
            <begin position="135"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="5">
        <location>
            <begin position="260"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="203"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC93361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="519" mass="58675" checksum="A5D6210AD66638E2" modified="2018-07-18" version="1">MTNESSPIYVTPTSAMNEKNQADDMYRAPVVRKDLHEEKALEKISVEFAHFLDCSPVPTFVLDLNHVITHWNKACEHVLGFSSDFMLETKKQWMPFYRTQRPVLADLMLHNKVEEDVFGLFNDKIKPSFLAKGACEVDAYFENLGESGLWLHFTAAPLLNKQGDIIGAIQTLEDITERKEAEKSLRLAHSDLEILVKKRTAQLAEANIQLELDISEREKIESELIRRNNDLTELNSQLFKAQEQLVQSEKLASIGQLAAGVAHEINNPIGYIFSNFTTLENYISQLFEMIHAYENVEQHITAASVIAEIKDIKEKIELEYLKEDIPELMLQSKEGIGRVRKIVQDLKDFSRIDSNQEWQWSNLHEGMNSTLNIVNNEIKYKADVIKEFGDIPDVECLPSQINQVIMNLVMNATHAIGAERGRIVIRTSRENDNAKIVVEDNGSGIPKDILSKIFDPFFTTKPIGKGTGLGLSLSYGIIQKHNGHIEVVSELGKGTSFIITLPIKHDYAESDDEGQANEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0C2</accession>
    <name>A0A2S9H0C2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Type I phosphodiesterase / nucleotide pyrophosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1819</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93432">
        <property type="protein sequence ID" value="PRC93432"/>
        <property type="gene ID" value="S2091_1819"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002591">
        <property type="entry name" value="Phosphodiest/P_Trfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01663">
        <property type="entry name" value="Phosphodiest"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="481" mass="53844" checksum="DE85F81AE32206C1" modified="2018-07-18" version="1">MNSTMQPLIILNLVGLSPRLLGEFTPQLRRFAKEGTLQPLQTVIPAVTCSVQASILTGLTPSEHGIVGNGWYAKDIAEINFWRQSNRLIQGEKIWETAKKRDPKFTCANLCWWYNMASSHDIGLTPRPIYKADGRKLPDCYTKPASWRESLTRDLGNFPLFQFWGPGTSIASSRWIAEAAKHAIREFDPTLSLVYLPHLDYDLQRYGPDLQHPAVQQSLKDIDAVAGDLIRHAQAAGRRVLVLSEYGITPVDRAIHINRHLREAGYLAVRTEDGAEQLDPIASDAFAVADHQIAHVYVADPELIEPIRQLLLAIPGVESVWAGNERADISLEHERAGDLIVMSDERSWFSYYYWLDDLLAPDFARTVEIHRKPGYDPAELFVAPHISYPKLAIATRLLKRKFGLRSLMNVIGLDASLVKGSHGRPTNDPLDGPLIIGEKTLALPLNISVTDVKDIVLDLIFEPASMPRTNESIPSSEQWQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0C4</accession>
    <name>A0A2S9H0C4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1821</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93434">
        <property type="protein sequence ID" value="PRC93434"/>
        <property type="gene ID" value="S2091_1821"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="151" mass="16953" checksum="478917E27CF3A011" modified="2018-07-18" version="1">MSELIAPNSLKDLVDAHAIHHATVVADKAAFKINVKYGMVERTVSVRTRDGQIKERVFTSLDAVARFMRDKIHLTQYDINAANFDPSAKAVKRPDTAKRLTAAHAALSHSEWAQQKVQAAREGMLNGTNKLIEPDEWTAIRQAKQRHRDTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0G5</accession>
    <name>A0A2S9H0G5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">GGDEF: diguanylate cyclase (GGDEF) domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1862</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93475">
        <property type="protein sequence ID" value="PRC93475"/>
        <property type="gene ID" value="S2091_1862"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="41"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="68"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="99"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="122"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="145"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="173"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="2">
        <location>
            <begin position="238"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="373" mass="41846" checksum="EA3D35196B80EDA0" modified="2018-07-18" version="1">MWAGEFIKNVMGTLDSRSLRELPPQIEVEVESRHEEEIFHLLPLLGPLFGCGILLFSAWDYLIDPAHAWSTFLVRLLLVLLGSIAYVPNRLQWSPVQRCGVIYGTHSCAIIISEYLLNNGFLYGLTGIAACIFVVSVITLRVRTFLLILSAPTLLFLILSAIRFPLFEFINSVMLYIFSVACAGIVMLVIRYFRLKAFSLEKKLLHISHHDSLTGAYNRGYLTELAVREIALAKRHGRALCVAMIDIDHFKSVNDTYGHAVGDETIKLLVKTCEQNLREIDHFGRIGGEEFVCILPETAESDAMLCAERLRRSIEEMRIKIPSGYLQVTASIGVAVLIQQPDWDALLKDADTALYSAKRDGRNRVVLATTCIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0G9</accession>
    <name>A0A2S9H0G9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1840</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93453">
        <property type="protein sequence ID" value="PRC93453"/>
        <property type="gene ID" value="S2091_1840"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="841" mass="97365" checksum="AC2968B6601AF0BF" modified="2018-07-18" version="1">MTNKDHINRLLPDADGLDFEGLRRHGIELLQGLSGGRWTDYNLHDPGVTLLEMLCYGLTDLVYRTDFNVEDFLTGENGEIDYQQQALYPPQEIFPNQALTDLDYCKLIYDHLPNVEDVWIRSHTEDKAMRGLFTIFIKPQESIFRDKKEEIEHAQQVLRADVTALVSANRNLCRDIHEVKIVNPQEFSLAGDIEIDDSRPRAEIYADIYFRCAKLISSGSQIVRFEEALQQGMKWEEILCGPLTNRGYIDENNFLQDSYDIDVIKLITLVRHIPGVKNVRSLSLINDQGAVYEHLEFDHSDVDYPVLHFIDDTDKILALRLQHGRSVSVDVSQNTDINQSHSPQSQREIQAFGEQVMLYLKKQEFEHEAFRRNRGNIDSIIQLPHGQSRDFAQYLSVGENTPAIYGINHHGVPKSESDAVHARAKQLKAYLYPFEQIMANYLGSLQHVRELYSIDEVVNQSYFSTYLQNAEIPNIQELYVPDANAKEIAQILREQDQFEERRNRVLDTLLAIYGEQFPEKELQRYDYYHQGQFAQSLIRCKIQLLKHLCELSSRRGGAINLQKNWKDNSGAILQKRIQILMGCYQDTNNTSLVAALQDNTKYVSNSRYQDKLHKQIGVPNEIAAEKLILIAKKNGAEAFADFKLPHDSICDAVLQAGVSWDNYRIFKVDEQHGWLCLIVQHEEVWPIILMPLDEISAFTQKMIEVLSSISQQCEGFHLVEHLLLRPRANNTDRQITHDFYCHRVSIILPAFTARFADIPARYWIENMIAEQLPAHIMPEFYWLDFPFLAQFELRYQKWLSQLQVYASANYQGETGDLDSSANGIIEFLKKNRHSQSNRYWI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0I9</accession>
    <name>A0A2S9H0I9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Activator of Hsp90 ATPase 1-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1878</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AHA1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93491">
        <property type="protein sequence ID" value="PRC93491"/>
        <property type="gene ID" value="S2091_1878"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013538">
        <property type="entry name" value="Activator_of_Hsp90_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08327">
        <property type="entry name" value="AHSA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="151" mass="16937" checksum="0F3135AD7D5655FC" modified="2018-07-18" version="1">MMDILHRVGIKASLNEVYKALGTREGLAAWWTDNTQGESKVGGMLQFRFSAGGSEIGSFEMKVLELHPAEGVLWQVVNGPPEWVGTKISFELKQDGEYCIVLFKHLGWKEPVEFMHHCSTKWAIFLMSLKSLLETGKGAPSPNDVKIDNWN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0W3</accession>
    <name>A0A2S9H0W3_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cys-tRNA(Pro)/Cys-tRNA(Cys) deacylase</fullName>
            <ecNumber evidence="3">4.2.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_1594</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.-.-" evidence="3"/>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93593">
        <property type="protein sequence ID" value="PRC93593"/>
        <property type="gene ID" value="S2091_1594"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA editing activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00002">
        <property type="entry name" value="YbaK_deacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.960.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004369">
        <property type="entry name" value="Prolyl-tRNA_editing_YbaK/EbsC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036754">
        <property type="entry name" value="YbaK/aa-tRNA-synt-asso_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007214">
        <property type="entry name" value="YbaK/aa-tRNA-synth-assoc-dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04073">
        <property type="entry name" value="tRNA_edit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006181">
        <property type="entry name" value="EbsC_YbaK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55826">
        <property type="entry name" value="SSF55826"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00011">
        <property type="entry name" value="YbaK_EbsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="tRNA_edit" evidence="4">
        <location>
            <begin position="39"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR006181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC93593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="165" mass="17850" checksum="6B2782BE17C853CB" modified="2018-07-18" version="1">MSHQKHISETPATQFLRKSGITFTEHPYTYEERGGTTVSARELGVDEHCVIKTLVMQNEAGKPLIVLMHGDCTVSTKNLARQIGCKSVAPCSPDIAQRHSGYQVGGTSPFGTKKALPVYVEKAILDLPKIYINGGRRGYLVGIAPQILIETLQAKAVECALAQAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0Z7</accession>
    <name>A0A2S9H0Z7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">BFD-like [2Fe-2S] binding domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1621</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93620">
        <property type="protein sequence ID" value="PRC93620"/>
        <property type="gene ID" value="S2091_1621"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007419">
        <property type="entry name" value="BFD-like_2Fe2S-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041854">
        <property type="entry name" value="BFD-like_2Fe2S-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04324">
        <property type="entry name" value="Fer2_BFD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fer2_BFD" evidence="1">
        <location>
            <begin position="2"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="73" mass="8246" checksum="C06C9B5EA07C044F" modified="2018-07-18" version="1">MIVCVCHNISESRIKTAIQQGINSMPLLRENLELGTCCGKCKSCTKKILRECMPHEDHKHGQHHPIHFHAMAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H140</accession>
    <name>A0A2S9H140_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">tRNA (cytidine(34)-2'-O)-methyltransferase</fullName>
            <ecNumber evidence="4">2.1.1.207</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmL</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">trmL</name>
        <name evidence="7" type="ORF">S2091_1706</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>5-carboxymethylaminomethyluridine(34) in tRNA(Leu) + S-adenosyl-L-methionine = 5-carboxymethylaminomethyl-2'-O-methyluridine(34) in tRNA(Leu) + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:43088"/>
            <dbReference type="Rhea" id="RHEA-COMP:10333"/>
            <dbReference type="Rhea" id="RHEA-COMP:10334"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74508"/>
            <dbReference type="ChEBI" id="CHEBI:74511"/>
            <dbReference type="EC" id="2.1.1.207"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>cytidine(34) in tRNA + S-adenosyl-L-methionine = 2'-O-methylcytidine(34) in tRNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:43084"/>
            <dbReference type="Rhea" id="RHEA-COMP:10331"/>
            <dbReference type="Rhea" id="RHEA-COMP:10332"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74495"/>
            <dbReference type="ChEBI" id="CHEBI:82748"/>
            <dbReference type="EC" id="2.1.1.207"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.207" evidence="4"/>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93705">
        <property type="protein sequence ID" value="PRC93705"/>
        <property type="gene ID" value="S2091_1706"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008175">
        <property type="term" value="F:tRNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd18094">
        <property type="entry name" value="SpoU-like_TrmL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01885">
        <property type="entry name" value="tRNA_methyltr_TrmL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001537">
        <property type="entry name" value="SpoU_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016914">
        <property type="entry name" value="tRNA_cyt/urid_MeTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42971">
        <property type="entry name" value="PTHR42971"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00588">
        <property type="entry name" value="SpoU_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029256">
        <property type="entry name" value="SpoU_TrmH_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="SSF75217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00185">
        <property type="entry name" value="tRNA_yibK_trmL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 4 7" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="SpoU_methylase" evidence="6">
        <location>
            <begin position="2"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4 5">
        <location>
            <position position="80"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4 5">
        <location>
            <position position="102"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4 5">
        <location>
            <position position="124"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4 5">
        <location>
            <position position="132"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR029256-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC93705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="156" mass="17459" checksum="5629643E2BB6A9BD" modified="2018-07-18" version="1">MFHVVLVEPEIPPNTGNIIRLCANTGAQLHLIEPLGFPLEDSKLKRAGLDYHEYAKMRVHPNWQAFIDQLKPDPARMFALTTHGSALFSEARFQPGDVFVFGSETKGLDPALRNSFASEQRIRLPMQPDNRSLNLSNTVAIVVFEAWRQNGFLGGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1H8</accession>
    <name>A0A2S9H1H8_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptidyl-prolyl cis-trans isomerase</fullName>
            <ecNumber evidence="4">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_1426</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the FKBP-type PPIase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="4"/>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93817">
        <property type="protein sequence ID" value="PRC93817"/>
        <property type="gene ID" value="S2091_1426"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061077">
        <property type="term" value="P:chaperone-mediated protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000413">
        <property type="term" value="P:protein peptidyl-prolyl isomerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044609">
        <property type="entry name" value="FKBP2/11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001179">
        <property type="entry name" value="PPIase_FKBP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45779">
        <property type="entry name" value="PTHR45779"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00254">
        <property type="entry name" value="FKBP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50059">
        <property type="entry name" value="FKBP_PPIASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3 4" id="KW-0697">Rotamase</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015598787" description="Peptidyl-prolyl cis-trans isomerase" evidence="6">
        <location>
            <begin position="26"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="domain" description="PPIase FKBP-type" evidence="7">
        <location>
            <begin position="88"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="29"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="29"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC93817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="183" mass="19414" checksum="D35D91D12F06A610" modified="2018-07-18" version="1">MNHAQQLRAMIVVLTLSVCAFQHNAIAKQQETTTPVNQASEQSVEPTVAPEPVPALAPTPAPAPAPVPTPALVIKDTKIGKGAEAVAGQDVTVHYTGWLYDAKAKKFHGKKFDSSRDHGQPFKFPLGGHRVIQGWDQGVVGMKIGGKRTLIIPSELAYGTRGAGDVIPPGAKLVFDVELLAVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1K2</accession>
    <name>A0A2S9H1K2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="11">TonB-dependent Receptor Plug Domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">S2091_1446</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93837">
        <property type="protein sequence ID" value="PRC93837"/>
        <property type="gene ID" value="S2091_1446"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039426">
        <property type="entry name" value="BtuB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30069">
        <property type="entry name" value="PTHR30069"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="3 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 11" id="KW-0675">Receptor</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="2 6" id="KW-0798">TonB box</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015746183" evidence="8">
        <location>
            <begin position="23"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="domain" description="Plug" evidence="10">
        <location>
            <begin position="95"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="9">
        <location>
            <begin position="297"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="32"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="32"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC93837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="756" mass="82921" checksum="3A85A5DA6DD59D81" modified="2018-07-18" version="1">MSSLISTASFALLGLYSTHLLAEDVLQTAPEPTTTVQTPATSATPTATPAVIPTPSDTPDTPAPKKRHKEVLTDSSVPKVVISGAGQTDLDVRRQSTASKIIIGREELDRDGDSSVGEILKRLPGVTVGGKPGRGGDIRMRGMGSGYTQILVNGERMPRGFSLDTLSPDQVERIEIIRAPVAEFTTQAVAGIINIVLREDYKQKDTQLRLSDGVEQGRNAPNLSISTPGEIGQLSYTLSGSIFQNRRRDEAFTDNLINDEPGQKIVDQDIGVTNGVHLTPRFEYKFSDSDKLVMQPFVMFANTQTNGTSVLDQLNDQVAPYQNAVWHTGVNSFVSRLFTNYTHRLEDGAKLELKLGTGKSENSTITDRVQTGDATGYQDLLTTSHTEDFNTSVGAKYSKIFSNGHSLVTGVSADWTRRNETEVATDNGAPTFDNSGDNLSAGIRQLAGFVQDEWDINPNWAANAGLRWEGIQTTSTLPTGEILNQSSVWSPLLHLVYRIPDTKDQIRMSATHSYRPPVLNDLIALPALSQNNSPISPDRIGNPNLKPELANGIDVGYEHYISHSGILAANFFYREIHDLMRHEVSLVDGRWVSAPVNLANAQTHGIELEAKFDIVDFFPEAPAISLRSNYSHFWSQVADIQGPNNRIDQQPSQTANLGMDYKMATLPLTLGGSVNWTPAYIVQSSTTQGNTIGLKRQLDMYALWKFSASSQLRFAVNNLVNSDYLTSTFSTLGYPEVSTVVAPTYTTYTLRWELKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1M8</accession>
    <name>A0A2S9H1M8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1504</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93895">
        <property type="protein sequence ID" value="PRC93895"/>
        <property type="gene ID" value="S2091_1504"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="219" mass="24833" checksum="43F123A6658020BC" modified="2018-07-18" version="1">MKIAEVRDEIAVTVSSLFASHGFDVKKTSQAVVCVRKISGGKQEIEFVLHNYRPLYKISVMVCCRFDEMVNISNEICETDSRYHADALSSITKLDYFSGIKNQRCDVTTPEEIQNAINSLRPVLLEKVVPLLDRCLDFRTFEAILNSRSSPKFDFTYLPVAVVNSLIAAHLTGNQEFENLVIEAKHSLKEFSDENKQLLVKCVEYLRKYDSAKKNIGAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1S4</accession>
    <name>A0A2S9H1S4_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptidyl-prolyl cis-trans isomerase</fullName>
            <ecNumber evidence="4">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_1425</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the FKBP-type PPIase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="4"/>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93816">
        <property type="protein sequence ID" value="PRC93816"/>
        <property type="gene ID" value="S2091_1425"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001179">
        <property type="entry name" value="PPIase_FKBP_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00254">
        <property type="entry name" value="FKBP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50059">
        <property type="entry name" value="FKBP_PPIASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3 4" id="KW-0697">Rotamase</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015536661" description="Peptidyl-prolyl cis-trans isomerase" evidence="5">
        <location>
            <begin position="21"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="domain" description="PPIase FKBP-type" evidence="6">
        <location>
            <begin position="60"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC93816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="159" mass="16717" checksum="CDF6D5798DCBB506" modified="2018-07-18" version="1">MKISLPLIAAVIAISATLAACEPKNETQNNSKTNAPAQIAVTALSAKDTQIGTGAEALKDHQVTVHYTGWLYDSNADQFHGKQFDSSRDGAAGGQPFSFYLGAHQVIPGWDQGVAGMKVGGKRTLIIPSELAYGEQGAGRGVIPKNAPLVFEIELLAVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1T4</accession>
    <name>A0A2S9H1T4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="10">TonB-dependent Receptor Plug Domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">S2091_1435</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93826">
        <property type="protein sequence ID" value="PRC93826"/>
        <property type="gene ID" value="S2091_1435"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039423">
        <property type="entry name" value="TonB-dep_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32552">
        <property type="entry name" value="PTHR32552"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="3 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 10" id="KW-0675">Receptor</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="2 6" id="KW-0798">TonB box</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015596782" evidence="7">
        <location>
            <begin position="31"/>
            <end position="749"/>
        </location>
    </feature>
    <feature type="domain" description="Plug" evidence="9">
        <location>
            <begin position="68"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="8">
        <location>
            <begin position="273"/>
            <end position="747"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC93826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="749" mass="80713" checksum="8CAA1DF8BBE2EA8F" modified="2018-07-18" version="1">MNQFDLKPCALNVIRALSVMCLTAPMLVHAQQTTDLGVVGANGTATNSPAPVTEASKAALSQGSLDARSAQSVVSADFIDNFMSPVSDFSQVFQLTPGAFSYSPNGVGQGNAATTIRGLTDSQYLVTFDGIPFNDTNGVSHHSYVYFPAMEIGGAVVDRSPGTAATIGQATFGGSLNLLSRNLETAPRTSITGSYGTWDTGLVVLEHETGQFGPEGASNLLINAQQMTSDGYQTYNHQNREAFSGKYQYIVSADTVVTLFASYMDVRNNQLDAGAPTRAQVAQFGDNYLNSNDPTQSNYYGYNFYNVKTSFQYIDVASNLGNGWKLDNKFYNYGYHNQENIGGAVPQSTAKVLATANVPGNDTGIDKLNSYHTTGNILRVSKDTDLGTFRSGVWLEYANSDRHQYNSNELDSWQDEVTPRFSETYQTTTLQPYAEFEFKVTNDLKITPGLKLADYEQNYDHLQDLKKVGLLGGTLNKTTGVTTGGMPDVTNSVNYHDVLPTLDVHYQLQPNWSTYFQAAQGDLIPPTSVFDVPYAKVATPPKAQKSTTYQIGTVYKADKFTVDADVYHTKLDNSYSCATDPTDITTQICVASGTETTQGLELEGTLLLGGGFSIYANGTVGTTKYSTGQWVAGAPSDVETLGFIYADGGWNSSIIAKRVGKLYNDGAAAGDDSYTINPVVLTNMFVNYTVKNPTSFAKAAKVQLAVNNLFDKHNITGISGSGSDSNPLAGDFITMLPARSVALTVTVDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1W4</accession>
    <name>A0A2S9H1W4_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Type 3 secretion system secretin</fullName>
            <shortName evidence="2">T3SS secretin</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">sctC</name>
        <name evidence="5" type="ORF">S2091_1465</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Component of the type III secretion system (T3SS), also called injectisome, which is used to inject bacterial effector proteins into eukaryotic host cells. Forms a ring-shaped multimeric structure with an apparent central pore in the outer membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">The core secretion machinery of the T3SS is composed of approximately 20 different proteins, including cytoplasmic components, a base, an export apparatus and a needle. This subunit is part of the base, which anchors the injectisome in the bacterial cell envelope. Forms a stable homooligomeric complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 3">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the bacterial secretin family. T3SS SctC subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93856">
        <property type="protein sequence ID" value="PRC93856"/>
        <property type="gene ID" value="S2091_1465"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030257">
        <property type="term" value="C:type III protein secretion system complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030254">
        <property type="term" value="P:protein secretion by the type III secretion system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.120">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02219">
        <property type="entry name" value="Type_III_secretin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005644">
        <property type="entry name" value="NolW-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038591">
        <property type="entry name" value="NolW-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004846">
        <property type="entry name" value="T2SS/T3SS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003522">
        <property type="entry name" value="T3SS_OM_pore_YscC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00263">
        <property type="entry name" value="Secretin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03958">
        <property type="entry name" value="Secretin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01337">
        <property type="entry name" value="TYPE3OMGPROT"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02516">
        <property type="entry name" value="type_III_yscC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0653">Protein transport</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0811">Translocation</keyword>
    <keyword evidence="2 3" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5026408746" description="Type 3 secretion system secretin" evidence="2">
        <location>
            <begin position="18"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="domain" description="Secretin_N" evidence="4">
        <location>
            <begin position="177"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC93856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="562" mass="61128" checksum="43BC40E51D3F015A" modified="2018-07-18" version="1" precursor="true">MWLVVMALLFVYPKSSAVDLSAGDKSVVGTGTSAGYVARQENMRAFFGGVSSYLGKPIIVSKLAAGKQISGEFNFAAGDIVSKVCRELGLINYYDGNAIYVYDASETKNSVIKLKSVTPKALTSFLRKSGLADPRYPLRGDGIDTFYLAGPPIYVDLVTQAAEFMDSQRTGLDNQQVEVIKLNNTFVTDRAYTRRDESVVIPGIATVVEKLLAGEDAQVALTVQKSSSASPFLDEQIDRVAGASPDPSAAALKSANVAVQSQAAGNIRIIAYPETNSLLVKGTAEQIRFIRNLVEALDEEKRHVELALWIIDLEKDDLDQLGVNWQGSVSIGNQFSAGLNTGTSLNSFGTLEGNKFIASILALTRENKAQIVSRPVVLTQENTPAMFDNNRTFYTPLIAERAVELQKVTYGTLVHVLPRITTKGEIELSLNIEDGSEVPRNEADTQKTLPTVGRTKISTVARVPKGQSLLVGGYTRGESSEQIGKIPLLGDLPFIGGAFRYHQTLNKNTVRVFLIRPREIVDGLDLDAENLDESVEFETLIKKMDKTRETAHGQKEGLTDGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1Z5</accession>
    <name>A0A2S9H1Z5_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Imidazole glycerol phosphate synthase subunit HisF</fullName>
            <ecNumber evidence="9">4.3.2.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">IGP synthase cyclase subunit</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">IGP synthase subunit HisF</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">ImGP synthase subunit HisF</fullName>
            <shortName evidence="9">IGPS subunit HisF</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">hisF</name>
        <name evidence="11" type="ORF">S2091_1175</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8 9">IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>5-[(5-phospho-1-deoxy-D-ribulos-1-ylimino)methylamino]-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + L-glutamine = 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate + H(+) + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:24793"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58278"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:58475"/>
            <dbReference type="ChEBI" id="CHEBI:58525"/>
            <dbReference type="EC" id="4.3.2.10"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 9">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 5/9.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 9">Heterodimer of HisH and HisF.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9 10">Belongs to the HisA/HisF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.3.2.10" evidence="9"/>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94002">
        <property type="protein sequence ID" value="PRC94002"/>
        <property type="gene ID" value="S2091_1175"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000107">
        <property type="term" value="F:imidazoleglycerol-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04731">
        <property type="entry name" value="HisF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01013">
        <property type="entry name" value="HisF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006062">
        <property type="entry name" value="His_biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004651">
        <property type="entry name" value="HisF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00977">
        <property type="entry name" value="His_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="SSF51366"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00735">
        <property type="entry name" value="hisF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9 10" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 9 10" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="7 9" id="KW-0456">Lyase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" evidence="9">
        <location>
            <position position="12"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00025475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC94002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="254" mass="26945" checksum="37E71935C5B49A9B" modified="2018-07-18" version="1">MTLAKRIIPCLDVTAGRVVKGINFTELRDAGDPVEIARRYDAQGADEITFLDITASSDDRDLILPIIEAVASQVFIPLTVGGGVRVVEDVRRLLNAGADKVSMNTSAVTNPQLVADAAQKYGSQCIVVAIDAKQTAPGYWQVYTHGGRNATGLDVVEWARKLEQLGAGEILLTSMNKDGTKSGFDLALTRAVSDAINIPVIASGGVGSLQDLADGIQLGHADAVLAASIFHYGQHTVKEAKEYMAARGIPMRLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H229</accession>
    <name>A0A2S9H229_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1215</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94042">
        <property type="protein sequence ID" value="PRC94042"/>
        <property type="gene ID" value="S2091_1215"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="103" mass="11618" checksum="B9C909D856C4744F" modified="2018-07-18" version="1">MTGIDQQTHTQQRPPLLTHLAVDTIDAYTQARDIISDFSAIFEVLDHLALEGLCSDRISRILFRAGFCHATERLKFIDERISDAYKTLDELKADSGHTLNDAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H266</accession>
    <name>A0A2S9H266_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">MMSDH: methylmalonate-semialdehyde dehydrogenase (Acylating)</fullName>
            <ecNumber evidence="4">1.2.1.18</ecNumber>
            <ecNumber evidence="4">1.2.1.27</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_1254</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.18" evidence="4"/>
    <dbReference type="EC" id="1.2.1.27" evidence="4"/>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94081">
        <property type="protein sequence ID" value="PRC94081"/>
        <property type="gene ID" value="S2091_1254"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018478">
        <property type="term" value="F:malonate-semialdehyde dehydrogenase (acetylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004491">
        <property type="term" value="F:methylmalonate-semialdehyde dehydrogenase (acylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07085">
        <property type="entry name" value="ALDH_F6_MMSDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010061">
        <property type="entry name" value="MeMal-semiAld_DH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43866">
        <property type="entry name" value="PTHR43866"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01722">
        <property type="entry name" value="MMSDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
        <property type="entry name" value="ALDEHYDE_DEHYDR_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldedh" evidence="3">
        <location>
            <begin position="19"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC94081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="504" mass="53577" checksum="075C4C6511816BA8" modified="2018-07-18" version="1">MTNAASQLPTVKLIINGEFVESSSREWRDIINPATQEVIARVPFATPDEINAAVSAAKEAFTTWRKAPIGTRARIFLKYQQLIRENMKELAAILTAEQGKTLPDAEGDIFRGLEVVEHAANIGNLQMGELANNVAGGVDTYTLLQPIGVCAGITPFNFPAMIPLWMFPMAIACGNTFVLKPSEQDPMVTMRLVELALQAGIPPGVLNVIHGGEQAVNAICDHPDIKAISFVGSTKVGTHVYHRGTLAGKRVQCMMGAKNHAVILPDANKQQTINSLVGATFGAAGQRCMAVSVALLVGDAKDWIADLVSTAKTLKVNAGTEPGTDVGPVISCAAYDRVATMIERGIAEGAKLELDGRNPKVPGYEKGNFIGPTIFSGVKPGMTIYDQEIFGPVLCLATVATLQEGIAMINANPNGNGTAIFTQSGAAARVFQEEIDIGQVGINVPIPVPVPLFSFTGSRASKLGDLGPYGKQVITFYTQTKTITQRWFDDSTLSAGVNTTIALK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H297</accession>
    <name>A0A2S9H297_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">LysR substrate binding domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1261</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94088">
        <property type="protein sequence ID" value="PRC94088"/>
        <property type="gene ID" value="S2091_1261"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="4"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="298" mass="32692" checksum="C6BDA02DAEDBF1EC" modified="2018-07-18" version="1">MNPTDLNLLIALDALLTEGSVTGAAERLNISAPTMSRTLNRIREMVGDPIFVRAGRGLVPTPRAEALREGTRELIQKANILLRNDDGFDFHTLQRTFSIRADDGFITSFGPILLGLLADAAPDVQLRFRPQGLQDVDSLRDGKIDLDIGVIPDIGPEIIRQSLFQDRFVAVFRVGHPLDRIDVLTPQLFAQQRHITVSRRGRMSGPVDDALAALGLSRKVVAVAPTFTEALAIARETDLIATVAERSTQTVRYGMRTSELPVPTPIVSISQAWHPRFGSDPGHRALRALVRQCCQPGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2G6</accession>
    <name>A0A2S9H2G6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">MarR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1229</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94056">
        <property type="protein sequence ID" value="PRC94056"/>
        <property type="gene ID" value="S2091_1229"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12802">
        <property type="entry name" value="MarR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00598">
        <property type="entry name" value="HTHMARR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00347">
        <property type="entry name" value="HTH_MARR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50995">
        <property type="entry name" value="HTH_MARR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="1">
        <location>
            <begin position="15"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="158" mass="17777" checksum="D842AF309872004F" modified="2018-07-18" version="1">MTANKKQKLKASNLKSHLGFWMRLVSNNVSQSFARKLEKMDVTVAEWVVIREMYSGDDTTSPGVVSELTGLTRGAVSKLISKLLEKKLVTRTEAVEDRRYQDIRLTETAIAMVPKLAKLADANDEEFFGVLSTEEREALAAVLTKIVIHNHLKKYPID</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2G7</accession>
    <name>A0A2S9H2G7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Thioredoxin-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1347</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94174">
        <property type="protein sequence ID" value="PRC94174"/>
        <property type="gene ID" value="S2091_1347"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5016432028" evidence="1">
        <location>
            <begin position="23"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="2">
        <location>
            <begin position="17"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="158" mass="17398" checksum="D63AD413B6FDC49B" modified="2018-07-18" version="1">MKKIYLYVVTLTALFISSIAFAATNLPYDETADSAVNIQTALIQAKANKKNVLLIFGANWCKDCVELDRSLKGKSASLIDKKFVVVKIDIGQFDKNLNIANDYGNPIKMGIPAAVLLKPDNTVLYATHGGELANARHMSEQGVYDFFNTITAQRKPIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2R6</accession>
    <name>A0A2S9H2R6_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8 13">Glutamyl-tRNA reductase</fullName>
            <shortName evidence="8">GluTR</shortName>
            <ecNumber evidence="4 8 13">1.2.1.70</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">hemA</name>
        <name evidence="17" type="ORF">S2091_0854</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8 13">
            <text>(S)-4-amino-5-oxopentanoate + NADP(+) + tRNA(Glu) = H(+) + L-glutamyl-tRNA(Glu) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:12344"/>
            <dbReference type="Rhea" id="RHEA-COMP:9663"/>
            <dbReference type="Rhea" id="RHEA-COMP:9680"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57501"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78520"/>
            <dbReference type="EC" id="1.2.1.70"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 8 13">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; 5-aminolevulinate from L-glutamyl-tRNA(Glu): step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer.</text>
    </comment>
    <comment type="domain">
        <text evidence="8">Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="8">During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8 13">Belongs to the glutamyl-tRNA reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.70" evidence="4 8 13"/>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94233">
        <property type="protein sequence ID" value="PRC94233"/>
        <property type="gene ID" value="S2091_0854"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00251">
        <property type="reaction ID" value="UER00316"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008883">
        <property type="term" value="F:glutamyl-tRNA reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006782">
        <property type="term" value="P:protoporphyrinogen IX biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00087">
        <property type="entry name" value="Glu_tRNA_reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000343">
        <property type="entry name" value="4pyrrol_synth_GluRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015896">
        <property type="entry name" value="4pyrrol_synth_GluRdtase_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015895">
        <property type="entry name" value="4pyrrol_synth_GluRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018214">
        <property type="entry name" value="GluRdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036453">
        <property type="entry name" value="GluRdtase_dimer_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036343">
        <property type="entry name" value="GluRdtase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006151">
        <property type="entry name" value="Shikm_DH/Glu-tRNA_Rdtase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00745">
        <property type="entry name" value="GlutR_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05201">
        <property type="entry name" value="GlutR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01488">
        <property type="entry name" value="Shikimate_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000445">
        <property type="entry name" value="4pyrrol_synth_GluRdtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69075">
        <property type="entry name" value="SSF69075"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69742">
        <property type="entry name" value="SSF69742"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01035">
        <property type="entry name" value="hemA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00747">
        <property type="entry name" value="GLUTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8 11" id="KW-0521">NADP</keyword>
    <keyword evidence="6 8 13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7 8 13" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GlutR_N" evidence="16">
        <location>
            <begin position="6"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="domain" description="Shikimate_DH" evidence="15">
        <location>
            <begin position="178"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="domain" description="GlutR_dimer" evidence="14">
        <location>
            <begin position="326"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="8 10">
        <location>
            <begin position="56"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="8 10">
        <location>
            <begin position="120"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="8 9">
        <location>
            <position position="57"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8 10">
        <location>
            <position position="115"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 10">
        <location>
            <position position="126"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 11">
        <location>
            <begin position="195"/>
            <end position="200"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="site" description="Important for activity" evidence="8 12">
        <location>
            <position position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000445-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000445-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000445-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR000445-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF01488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF05201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="PRC94233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="425" mass="46715" checksum="27E3A858517566F9" modified="2018-07-18" version="1">MQLLAVGLNHTTASLALREKVVFAPDKIGQAVLAARQFLYRNNASANTAEAAILSTCNRTELYAACKMPHPLDAAAHFLADYHQLPYAELRPHLYALPQDDAVRHAFRVASGLDSMVLGEPQILGQLKDAVRQSDEVGGLGTYLHQLFQRTFSVAKEVRSSTEIGAHSVSMAAAAVRLAQRIFDDLTEQHVLFIGAGEMIELCATHFAAQNPKSITIANRTLERGATLAHQFNGRAIRLAELPDQLAHFDIVISCTASTLPIIGLGLVERAIKARKHKPMFMVDLAVPRDIEAEVARLNDVFLYTVDDLGNVVQTGIESRQLAVVEAEAIIETGVQSFMHWIDGRAVVPVIQELHENGEAMRLMELERARRMLAKGDDIDVVLEALSKGLTAKFLHGSQQALHKTHGEERAQIAALLPQLFRTKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2V2</accession>
    <name>A0A2S9H2V2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Ion transport protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">S2091_0936</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94315">
        <property type="protein sequence ID" value="PRC94315"/>
        <property type="gene ID" value="S2091_0936"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008076">
        <property type="term" value="C:voltage-gated potassium channel complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005249">
        <property type="term" value="F:voltage-gated potassium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005821">
        <property type="entry name" value="Ion_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028325">
        <property type="entry name" value="VG_K_chnl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11537">
        <property type="entry name" value="PTHR11537"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00520">
        <property type="entry name" value="Ion_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10" id="KW-0407">Ion channel</keyword>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0630">Potassium</keyword>
    <keyword evidence="5" id="KW-0631">Potassium channel</keyword>
    <keyword evidence="3" id="KW-0633">Potassium transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="41"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="66"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="97"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="160"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="221"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="domain" description="Ion_trans" evidence="12">
        <location>
            <begin position="37"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PRC94315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="288" mass="32710" checksum="9F356CEA8C656CFD" modified="2018-07-18" version="1">MSTLKPTTSNGTAQNRDWRDRLYTIIFEADTDAGRRFDKMLLVLIVLSVATVIIDSVGAIRSNDYFVLNALEWLFTVLFTIEYVVRLLCVKHPLRYALSWFGIVDLISILPTYLAIIFPEFYYLIDVRLLRMLRVFRILKLPRYFDESQILWQALRNSRVKIMVFLGVVLIMSVILGTIMYVVEGPENGFTSIPVGMYWSIVTLTTTGYGDIHPKTPLGQLITSCAMLLGYGIIALPTGIVGVELAMTMMKRVPTTRTCSSCITEGHESDSTFCKHCGEKLDPYQFEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H311</accession>
    <name>A0A2S9H311_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative dithiol-disulfide isomerase involved in polyketide biosynthesis</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0944</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94323">
        <property type="protein sequence ID" value="PRC94323"/>
        <property type="gene ID" value="S2091_0944"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001853">
        <property type="entry name" value="DSBA-like_thioredoxin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01323">
        <property type="entry name" value="DSBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DSBA" evidence="1">
        <location>
            <begin position="2"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="212" mass="23743" checksum="9FE2D7EFF60DEDAA" modified="2018-07-18" version="1">MRIDIVSDVACPWCAVGLNSLERALEKIGDDIPVQLHFQPFELNPTMDFAGVDSAEYLLKKYGMSKEQLAQNRLNLHQRGAEVGFQFGTGNRVWNTFHAHRLMHWAGLQNIPDVQRKLKHALLQAYHGEGLNTADPETLVTVAVKAGLNEAQAREVVNSDLYSDEVREAEKYWQQAGISSVPAFIINQKHLISGGQPPNVFVEALRKIAEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H385</accession>
    <name>A0A2S9H385_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1065</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94444">
        <property type="protein sequence ID" value="PRC94444"/>
        <property type="gene ID" value="S2091_1065"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007435">
        <property type="entry name" value="DUF484"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38765">
        <property type="entry name" value="PTHR38765"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04340">
        <property type="entry name" value="DUF484"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="214" mass="23970" checksum="C4A901B4D886548D" modified="2018-07-18" version="1">MNHIEVASFLATNPHFFEEHAELLGTIKLSSPLLGRAVSLQERQMEVVRDKYRHLELRLSELLRMAQENDNATAKFQKWTNSLLLARNDVDLPHLLTTNLQEFFSLPHASLRLWNVAEEYQHAWFASPASDDIRLFARGLNAPFCGENKDFEAASWIDAPVASLAMLPLRANGEVIGLLVLGSSDKYRFTSTMATDLLSQIADTSSAALSCLIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3C4</accession>
    <name>A0A2S9H3C4_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein Smg homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">smg</name>
        <name evidence="2" type="ORF">S2091_1103</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Smg family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94482">
        <property type="protein sequence ID" value="PRC94482"/>
        <property type="gene ID" value="S2091_1103"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00598">
        <property type="entry name" value="Smg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007456">
        <property type="entry name" value="Smg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38692">
        <property type="entry name" value="PTHR38692"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04361">
        <property type="entry name" value="DUF494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="153" mass="17409" checksum="B83F0CB1FC4117D4" modified="2018-07-18" version="1">MFDILVYLYETYYRPDACPEPQALAKKLSAVGFDEDEISEAIDWLDILTQTTLTIPEQPESTGFRVYATQEIAMLGIPAVGFIHFLESAKLLTSQQREIVIERALAVDDTPITLDKLKIIVLMMLWSQGKEPDLLMFDELLLSDEVIKPHLLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3D6</accession>
    <name>A0A2S9H3D6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0997</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94376">
        <property type="protein sequence ID" value="PRC94376"/>
        <property type="gene ID" value="S2091_0997"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015646370" evidence="1">
        <location>
            <begin position="22"/>
            <end position="422"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="422" mass="45653" checksum="7165C2B49E46B75C" modified="2018-07-18" version="1">MRPVFLPLIYAALALPVTALADDAGVHGYALTDLIQTQARSTAANPDNLFGAGGGAGELALGLEGNVSGVRWRTRLTVDSESYSGSGSPTERYASLQELYYGWLWGERWHFSAGQQLLTWDNGMSFQPLGFFKSSQTDLRDVFDTEGRSQGIPMLVATYLGDSVTTDIVASTSNPGNNQAEQTNARQLAIRWSGELAPGLNTALMLRKRDSARVGAGVSTSYGVDEVTLHADAYYGPAEAREFPVGLLSGPAQLFLPPLEFSYDPGHDYVLRSVIGATWTPQRGVALYGEWVHHGDGVSGSQWKLYNEQLALHTAALNGPYHDAAVGNLGTDLSLLGSTPNGVRRDYLYLRAELGQGDATWFLSTFAGVADGSAMTTLSKTWKLRDHLTLEADLNAFTGKANSEFGLTPYRYQAHLVLLKTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3D9</accession>
    <name>A0A2S9H3D9_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protease 4</fullName>
            <ecNumber evidence="3">3.4.21.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Endopeptidase IV</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Protease IV</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Signal peptide peptidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_1098</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the peptidase S49 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.-" evidence="3"/>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94477">
        <property type="protein sequence ID" value="PRC94477"/>
        <property type="gene ID" value="S2091_1098"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006465">
        <property type="term" value="P:signal peptide processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07023">
        <property type="entry name" value="S49_Sppa_N_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004634">
        <property type="entry name" value="Pept_S49_pIV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004635">
        <property type="entry name" value="Pept_S49_SppA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002142">
        <property type="entry name" value="Peptidase_S49"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01343">
        <property type="entry name" value="Peptidase_S49"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001217">
        <property type="entry name" value="Protease_4_SppA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00705">
        <property type="entry name" value="SppA_67K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00706">
        <property type="entry name" value="SppA_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 3 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="24"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S49" evidence="6">
        <location>
            <begin position="133"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S49" evidence="6">
        <location>
            <begin position="390"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="201"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4">
        <location>
            <position position="404"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR001217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR001217-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC94477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="618" mass="67666" checksum="DC7EA3A7F9C83C97" modified="2018-07-18" version="1">MSLLRYAQRSFSFLWRMLDGGRRIFLNLLFLIVIIFIAVGLFGGGIKKLDDKTALILDLRGNLVEQQSGSTSQLLMMQAQGEKKDYTQLRDVLDVLDAAAKDKKITSIVLLLDEMQNAGLPMLREVAAGLDRFKASGKTIVAWGSSFNQKQYFLAAHANEVYVHPMGMVALEGFGGYKNYYRDALDKLGITVNLMRVGTYKSFAEPYIANGPSNAASEAEAFLYNDLWATYTNDVEKARKLGSGSIMRNIDDLPNQIKQVNGDLAQLALNDKLVDGLKTRDELRQLMLDRGVKDAQTKSFRQVNYEDYLARQKPIINPNGNAIGVIVAEGEISDGMAPPGSIGGLSTANLIRKAREDDQIKALVLRIDSPGGSAFGSELIRRELEITRLAGKPVVVSMGNVAASGGYWISMSADEVFADAATITGSIGVFALLPTADKAMEKIGVHSAGTTTTWLRGGYDPMRPIDPRFAELIQQSVNHIYAEFTSKAAVARKSTPEKIDEVAQGRVWTGQQAKERGLVDTLGSYGDAIKSAAARAKLTGNYNVDYIEAEPTGLDRFFKIFDISIAKVVSDHFNVNILPAGIPPKAAQEMTNDMRWLSDMTDRNKAFSVVTHCMCSVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3G9</accession>
    <name>A0A2S9H3G9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC-type sugar transport system permease component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_0510</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94507">
        <property type="protein sequence ID" value="PRC94507"/>
        <property type="gene ID" value="S2091_0510"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008643">
        <property type="term" value="P:carbohydrate transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="76"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="107"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="143"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="182"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="242"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="72"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC94507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="274" mass="30605" checksum="959C5D996B232AC8" modified="2018-07-18" version="1">MRIPTKKLSLAGQYLLLTALAVLCVFPFWWTLVTAISTEGNIFAFPPTFWPQAPSLENFIEVFRSIPMWLFYRNSLIITISTVFWKLLVCSLAAYPLARMKFKGSKLVFGLIIATMVLPSEVNFLTNFITLTKLSLVNTYTGVILPNVVNAVSILLLKQAFEEVPQDLIDAARVDGATEWIIFWKIVLPLITPWLATVGILSAVEAWNEYIWPSIVLSKPESFPLSAGILYLRGAYGSSTRVIAAGTILTIVPILVAFIFTQRFFMRGMDGAVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3H9</accession>
    <name>A0A2S9H3H9_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Acetate kinase</fullName>
            <ecNumber evidence="6">2.7.2.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Acetokinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ackA</name>
        <name evidence="8" type="ORF">S2091_0520</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>acetate + ATP = acetyl phosphate + ADP</text>
            <dbReference type="Rhea" id="RHEA:11352"/>
            <dbReference type="ChEBI" id="CHEBI:22191"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.2.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="6">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="6">Mg(2+). Can also accept Mn(2+).</text>
    </comment>
    <comment type="pathway">
        <text evidence="6">Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the acetokinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.2.1" evidence="6"/>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94517">
        <property type="protein sequence ID" value="PRC94517"/>
        <property type="gene ID" value="S2091_0520"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00340">
        <property type="reaction ID" value="UER00458"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008776">
        <property type="term" value="F:acetate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006085">
        <property type="term" value="P:acetyl-CoA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006082">
        <property type="term" value="P:organic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00020">
        <property type="entry name" value="Acetate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004372">
        <property type="entry name" value="Ac/propionate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000890">
        <property type="entry name" value="Aliphatic_acid_kin_short-chain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023865">
        <property type="entry name" value="Aliphatic_acid_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21060">
        <property type="entry name" value="PTHR21060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00871">
        <property type="entry name" value="Acetate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000722">
        <property type="entry name" value="Acetate_prop_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00471">
        <property type="entry name" value="ACETATEKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00016">
        <property type="entry name" value="ackA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01075">
        <property type="entry name" value="ACETATE_KINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6 7" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6 7" id="KW-0808">Transferase</keyword>
    <feature type="active site" description="Proton donor/acceptor" evidence="6">
        <location>
            <position position="156"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="17"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="24"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="99"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="214"/>
            <end position="218"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="289"/>
            <end position="291"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="336"/>
            <end position="340"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="387"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="6">
        <location>
            <position position="187"/>
        </location>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="6">
        <location>
            <position position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC94517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="401" mass="43433" checksum="9F99F5D30E03D46D" modified="2018-07-18" version="1">MTDQSTQSTTALIMVLNCGSSSIKFALFEASQTSLPRKPVWSGKVDGITGTNPTWDETGAGTCALTLDPQLPYHAALGEIRTRVTARLAGRKIDAIAHRVVHGGNKYFAPTRINADVLADLKNLIPLAPLHQPFALEAIAALLESQPELPQIACFDTAFHHTLPIVEQMLPLPWENWEQGMRRYGFHGLSYNYMSVVLAERYGELARGRTIVAHIGSGASLCAMQNLQSVATTMGFSALDGLMMGTRCGTLDPGAVLYLMEIRKLSLEQVGHMLYHESGLLGISGVSADTRILLQQEAGNARVQAALQLYVRRIVREIGALTAVLGGLDMLVFTAGVGEHNAELRQRICTALGYLGIRLESADNERHAAVISSDDSGVKVVVEPTNEEWIAALGVTKMELF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3N0</accession>
    <name>A0A2S9H3N0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0595</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94592">
        <property type="protein sequence ID" value="PRC94592"/>
        <property type="gene ID" value="S2091_0595"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="295" mass="33445" checksum="59719F35CB37B202" modified="2018-07-18" version="1">MDLNSVRMFVAVVQAGSLSTAAERVGIPLPTLSRRIRELESELNVRLFERHSQGVKVTEVGTRLYEHAARGIESLEDAERAVVSNDEAQLTGTLRLSIPPAFEPWWELVAEFQRQHRHVTVTVYTTERRVELVEDGIDVALRVGAIVHEQMVARKLFSYRHVLVASPKLLAEFGEPSSPDELRRFPCGVWRRDTLSNHIWQLGDQMFEPSATLVTNDYLHLRNRAISGDLVTELPPFLAREAVANGTLCLLLPEYPLPMQDISLLYPSRRFVPSIVRAYINFCQEQVVGFCEGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3Y1</accession>
    <name>A0A2S9H3Y1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0695</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94692">
        <property type="protein sequence ID" value="PRC94692"/>
        <property type="gene ID" value="S2091_0695"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="60" mass="6289" checksum="DF642A258116517B" modified="2018-07-18" version="1">MNRKFLIYAIVVTVLTTGITWQKLVASESNDQNRSGASRGSGWSSFMGNGSLAGGSGGHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3Y4</accession>
    <name>A0A2S9H3Y4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0683</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94680">
        <property type="protein sequence ID" value="PRC94680"/>
        <property type="gene ID" value="S2091_0683"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="4"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="304" mass="32974" checksum="33B333F8D653E6B7" modified="2018-07-18" version="1">MNKLKLNQLEMLIAVADSGGFGAAAAELGCTQSRISHAITELETTLKTRLLSRSRSGCVPTDAGYRVLTKARQILRLTHNIVDVVEDNAAVIGQVRIACFRSVGTHLLPHALAALAIEYPGIRIDIDDSCEEREDVSRAVMEGRADIGIAQLPVRSELVTHSFVSDSYVLVVPTSLQLRAPVSWDQLKVLPYIQLNCSGALAILEQCRAAGFTAELSRTLTTDTSIAAMVRHGVGYSILPRLAVYPEPSGVNIVDLPIPAQRQFALIALPDTARTKAVQIVTRFIRNKRITAKSDAVRAGLVSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H438</accession>
    <name>A0A2S9H438_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0696</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94693">
        <property type="protein sequence ID" value="PRC94693"/>
        <property type="gene ID" value="S2091_0696"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025235">
        <property type="entry name" value="DUF4178"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13785">
        <property type="entry name" value="DUF4178"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="437"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4178" evidence="2">
        <location>
            <begin position="56"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4178" evidence="2">
        <location>
            <begin position="275"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="482" mass="53032" checksum="32F98A24ABE3B604" modified="2018-07-18" version="1">MQIVPCPNCGAQIEFRSHASVLAVCEYCKTTVLKDAESVKNLGKMSDVLEDYSPIQIGTTGTFGGNAFTIIGRIQLRYSDGMWNEWYALFDNGKTAWLGDASGQYTLTTEIHANAQLPEFTALIPSHSYLINGQNYIAADVRTADCIGGQGELPFKIGQGWQAHVADLRSGRNFLTLDYSDSNQPQVYTGQAVSLDELKCQLLRDDDQVRTSAGKFKGKIEILACPHCGSSTQFLPGITTTIVCPSCHSQVDTSGPVSQILAAGERVEHVHTTLKLGAQATISGRQFQLIGLMQCSDNENTVWTEYLLHSPKAGFLWLIETTEGWARAIVLDEWPVWMQEDAAVLGKVPFHKLYRYPATVLFAAGAFNWRVGIGYRTEVVEFQGGQNKLAVEMTSSEITWSQSSPVSADQIRAWFGDAVVVNKTSTDENIKALSTKFIGLILALNLIPLLLSINTWIYVLIGGLAIYLPAKYLNSYFEEGNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4A2</accession>
    <name>A0A2S9H4A2_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protein-methionine-sulfoxide reductase catalytic subunit MsrP</fullName>
            <ecNumber evidence="5">1.8.5.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">msrP</name>
        <name evidence="7" type="ORF">S2091_0774</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a quinone + H2O + L-methionyl-[protein] = a quinol + L-methionyl-(R)-S-oxide-[protein]</text>
            <dbReference type="Rhea" id="RHEA:51296"/>
            <dbReference type="Rhea" id="RHEA-COMP:12313"/>
            <dbReference type="Rhea" id="RHEA-COMP:12314"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16044"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:45764"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a quinone + H2O + L-methionyl-[protein] = a quinol + L-methionyl-(S)-S-oxide-[protein]</text>
            <dbReference type="Rhea" id="RHEA:51292"/>
            <dbReference type="Rhea" id="RHEA-COMP:12313"/>
            <dbReference type="Rhea" id="RHEA-COMP:12315"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16044"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:44120"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Mo-molybdopterin</name>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
        </cofactor>
        <text evidence="5">Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the MsrP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.8.5.-" evidence="5"/>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94771">
        <property type="protein sequence ID" value="PRC94771"/>
        <property type="gene ID" value="S2091_0774"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043546">
        <property type="term" value="F:molybdopterin cofactor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016672">
        <property type="term" value="F:oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030091">
        <property type="term" value="P:protein repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01206">
        <property type="entry name" value="MsrP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022867">
        <property type="entry name" value="MsrP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000572">
        <property type="entry name" value="OxRdtase_Mopterin-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036374">
        <property type="entry name" value="OxRdtase_Mopterin-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00174">
        <property type="entry name" value="Oxidored_molyb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56524">
        <property type="entry name" value="SSF56524"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1 5" id="KW-0500">Molybdenum</keyword>
    <keyword evidence="4 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Oxidored_molyb" evidence="6">
        <location>
            <begin position="105"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="region of interest" description="Molybdopterin binding" evidence="5">
        <location>
            <begin position="87"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Molybdopterin binding" evidence="5">
        <location>
            <begin position="241"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="84"/>
        </location>
        <ligand>
            <name>Mo-molybdopterin</name>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="142"/>
        </location>
        <ligand>
            <name>Mo-molybdopterin</name>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
        </ligand>
        <ligandPart>
            <name>Mo</name>
            <dbReference type="ChEBI" id="CHEBI:28685"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="177"/>
        </location>
        <ligand>
            <name>Mo-molybdopterin</name>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="225"/>
        </location>
        <ligand>
            <name>Mo-molybdopterin</name>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="230"/>
        </location>
        <ligand>
            <name>Mo-molybdopterin</name>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC94771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="324" mass="36708" checksum="B00356ACB87D5464" modified="2018-07-18" version="1">MLIRSKPSNIILSSEITPREIFEARRQFIKQCAVGAIGSAGLLEMANRSAFAQNPGAQKLAAATNSNYVVIDNKTAYKDATTYNNYYEFGTDKSEPAQSAGSLKTRPWSVSIEGEINKPMKLDLDSLMKIAPLEERIYRLRCVEGWSMVIPWIGFSLSNLIKKVEPNSNAKYIEFTTLADKSQMPGLREGVLDWPYVEGLRMDEAMHPLALLTFGMYGEVLPNQNGAPVRMVLPWKYGFKSPKSIVKIRFTNKQPKTAWNTTAPREYGFYSNVNPEVDHPRWSQASERRIGEDGFFTKKRKTLMFNGYSEVASLYSGMDLKKYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4P2</accession>
    <name>A0A2S9H4P2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0149</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94954">
        <property type="protein sequence ID" value="PRC94954"/>
        <property type="gene ID" value="S2091_0149"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="76" mass="8655" checksum="213591104043E0D3" modified="2018-07-18" version="1">MNLRDFRIGWRLLVNEPDYSLAAAIERYLAGNVEHVAIGYRALLFALFMAFTIALIAVARHAWIAMHIHPIHVLIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4T2</accession>
    <name>A0A2S9H4T2_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 13 15">tRNA (guanine-N(1)-)-methyltransferase</fullName>
            <ecNumber evidence="6 13 15">2.1.1.228</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">M1G-methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">tRNA [GM37] methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">trmD</name>
        <name evidence="17" type="ORF">S2091_0187</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 13 15">Specifically methylates guanosine-37 in various tRNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 13 15">
            <text>guanosine(37) in tRNA + S-adenosyl-L-methionine = H(+) + N(1)-methylguanosine(37) in tRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:36899"/>
            <dbReference type="Rhea" id="RHEA-COMP:10145"/>
            <dbReference type="Rhea" id="RHEA-COMP:10147"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:73542"/>
            <dbReference type="ChEBI" id="CHEBI:74269"/>
            <dbReference type="EC" id="2.1.1.228"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="5 13 15">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 13 15">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 13 15">Belongs to the RNA methyltransferase TrmD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.228" evidence="6 13 15"/>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94992">
        <property type="protein sequence ID" value="PRC94992"/>
        <property type="gene ID" value="S2091_0187"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052906">
        <property type="term" value="F:tRNA (guanine(37)-N(1))-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd18080">
        <property type="entry name" value="TrmD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1270.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00605">
        <property type="entry name" value="TrmD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002649">
        <property type="entry name" value="tRNA_m1G_MeTrfase_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023148">
        <property type="entry name" value="tRNA_m1G_MeTrfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016009">
        <property type="entry name" value="tRNA_MeTrfase_TRMD/TRM10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46417">
        <property type="entry name" value="PTHR46417"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01746">
        <property type="entry name" value="tRNA_m1G_MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000386">
        <property type="entry name" value="tRNA_mtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="SSF75217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00088">
        <property type="entry name" value="trmD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 13 15" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 13 15" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11 13 14" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="10 13 15" id="KW-0808">Transferase</keyword>
    <keyword evidence="12 13 15" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="tRNA_m1G_MT" evidence="16">
        <location>
            <begin position="24"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="13 14">
        <location>
            <begin position="137"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13 14">
        <location>
            <position position="117"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00014679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR000386-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU003464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF01746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="PRC94992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="249" mass="27777" checksum="193B8FC7EAF093DE" modified="2018-07-18" version="1">MQFDVITLFPEMFAALTQSGVTRRAFEQKKCALTLWNPRDFTTDKHRTVDDRPYGGGPGMVMMVKPLQAAISAAKLRQTEQGFSAPRVIYLSPQGRPLTHQRVMQLGEYSGLVLLCGRYEAVDQRLLDSCVDEEISLGDFVLSGGELPAMALMDSMIRQLPGVLHDEDSAVQDSFVNGLLDCPHYTRPEMHDDVPVPEVLMSGNHAVIEQWRREQALKATLMKRPDLIKQARAAGLLSKSDEKYLSSKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4Z4</accession>
    <name>A0A2S9H4Z4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0233</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95038">
        <property type="protein sequence ID" value="PRC95038"/>
        <property type="gene ID" value="S2091_0233"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC95038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="79" mass="9055" checksum="5D6840B69A14A633" modified="2018-07-18" version="1">MAYLNTTYQLQSSFNSASSTINSSFLLRFGPREVSVCKDFRKRFYPTNPVIECRAGVNAGHVEVLLLRRWLVVFSKAEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H512</accession>
    <name>A0A2S9H512_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">TonB C terminal</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_0226</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95031">
        <property type="protein sequence ID" value="PRC95031"/>
        <property type="gene ID" value="S2091_0226"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037682">
        <property type="entry name" value="TonB_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03544">
        <property type="entry name" value="TonB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_C" evidence="3">
        <location>
            <begin position="520"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="170"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="198"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="366"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="198"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="238"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="258"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="420"/>
            <end position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC95031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="599" mass="66295" checksum="FDC38D15778D46F9" modified="2018-07-18" version="1">MTSWVTHFQQWWRSSDKTTTRLLVAVVISLALHAVLLLLQFGEYGEGLPGFELSLGDRRARTPEIHLNLQDPGNHPSANSTAHIENSQLADTLPPVVTPLPIPPLASTAFDLVPLPKPVEVPKVIEPIPTPPAKTSVRAPRTKPKLITTLNDATFKVASAEQAVIEPQMAEQELPAEIKPPIEEPEQAKPIEAMPDAEKLATEKAAAEKQEAEKLAKQKELEEKQAAKQEAQLKEQAEQAEQAKQQQAAADAAQRQAKALEQEVEHKKEQENQQKMQKQQADLQAAKEREQQAQAAAQLAAKLKQDELAKQQAQAEREKAEQAILAARTALEAEQRKLAEAVRIEQLKKEQAKKEQLERELAEVKRAEQEQKMKLAQQAEQLKAQQRENELKLEASRAAAQAQADAKARAEENQRQRSNDLDEVLGTSSGSSAGAGSGAAKPNLDKLLSGRSFDFDKNGDALKSNAAANLPALKSEHTSGVRRSIFGSKNIDVGLKLYIQSWRQKLEGNGRLNYSQSSKNHMHTDPIVTVSIRSDGSVENIVILRSSGRPDMDEAVRRIVTVNAPYSVFPVNLANKYDVIDIRQVWIFDDVLRITDEMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H520</accession>
    <name>A0A2S9H520_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Heavy metal efflux pump, CzcA family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_0280</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95085">
        <property type="protein sequence ID" value="PRC95085"/>
        <property type="gene ID" value="S2091_0280"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2090.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027463">
        <property type="entry name" value="AcrB_DN_DC_subdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001036">
        <property type="entry name" value="Acrflvin-R"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004763">
        <property type="entry name" value="CzcA/CusA/SilA/NccA/HelA/CnrA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32063">
        <property type="entry name" value="PTHR32063"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00873">
        <property type="entry name" value="ACR_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00702">
        <property type="entry name" value="ACRIFLAVINRP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82714">
        <property type="entry name" value="SSF82714"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00914">
        <property type="entry name" value="2A0601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="14"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="334"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="360"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="386"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="436"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="465"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="523"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="857"/>
            <end position="875"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="887"/>
            <end position="905"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="911"/>
            <end position="932"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="961"/>
            <end position="983"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="989"/>
            <end position="1015"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC95085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="1041" mass="114234" checksum="695189237434D75E" modified="2018-07-18" version="1">MIEKIVSTCFERRGITWIVFVFVALYGWFSWKQLPIEAYPDIADVTTQIVTQVPGLGAEEIEKQITIPLERALLSTPGMHVLRSRSTFSLSMITVVFKDGTEGYWSRQRLQERINDVDLPYDAKHGLDAYTSPIGEIYRYTLESKTRDLRELSELQQWTVMPRLMKVDGVVDVANFGGITTQFSLEIDPDKLVQYNLTLAQIKDAINDNNANAGGSVMDRGEQSYVIRGVGLLSSLEDMGNVVVTAKDGTPVLIKHLGAVNYSNPERRGILGKDDIPDSVSGITLLLKDFNASVALEGVHEAVRDLNENLLPKDVKVVPYLDRTDLINATMKTVGVTLLEGLCLVSIVLLLFLGSPRAAGIVALTIPLSMLIAFIFMHRFNIPANLLSLGAIDFGILVDGAVVLVENILRKREQNKDKPVTAKDAIQATLQVARPIFFGMGVIIAAYLPLFAFERIEYKLFSPMAYAVGSALIGALIVTLTLIPGLAYLAFRKPRKIFHNRVLEKITDRYSLFLNKMVGKTRWVIVTCGLALIGVVGLGASIGRDFLPYLDEGSLWLQVTMPPGITLDKATEMANQLRRTTLEFPEVSYIVTQTGRNDDGTDPWTPSHIEVSVGLHPYNTWKSGLSKQELIAKMETRYKQLPGYSIGFMQPMIDGVQDKLSGAHSDLVVKIFGDDFDEMRRIANDAINALNKVPGAADVSIDQEPPLPNLRVDLDRAAAARYGINAADVADLISTGIGGASIGQMYIGEKSYDMAVRFPEAARQSPEAISALLLTAANGAKIPLAQVATISLSSGESMITRESAKRHLTVKLNARDRDLSSFLKEAQTTLQRDVHYDHRHFQIEWGGQFENLERAEARLTVILPMTLAIMFLLLFGEFRNLRQPTLVLLAVPLAMLGGLAALHLRGMTLNVSSAVGFIALFGVAVLNGVLMLSQINRLRENKERGLMEAVLSGARSRIRPVLMTATVAAFGLTPAMLATGLGSDVQRPLATVVVGGLVTATLLTLVLLPALYYLIEARVERNALERKHAVDDNDDAELTVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H585</accession>
    <name>A0A2S9H585_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Arabinose efflux permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_0322</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95127">
        <property type="protein sequence ID" value="PRC95127"/>
        <property type="gene ID" value="S2091_0322"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="46"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="78"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="103"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="136"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="168"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="219"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="253"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="282"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="305"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="345"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="373"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="12"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC95127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="415" mass="44773" checksum="5965E465A9066ADE" modified="2018-07-18" version="1">MYQLPPGRERGLLWLLALTQFTIIMDFMVMMPLGPQIMHKFAIGPAAFATAVSAYAWCSGLSSLFAATYIDRFDRRKLLLVVYALFALSNLACASAPTFSMLLIARAFAGLTGGVLSSIIMAILGDVIPQNRRGAATGIIMTSFSLAAVAGVPAGIVLGAKFGWSSPFYLLVVLSLIIWLIGAKLVPTLTGHLAKKPAPLSRTLPDLINLIREPRHLRAYMLTFIMMTSHMLIIPFISPVIVANLNVAPQQLSWIYMAGGAATFFTSRFVGRMADRFGKHNLFRLTAVLSMLPILFITHLPTLPFMVLVAFFAVFMVLASSRMIPMQALLTTIPKPAQRGAFLSINSAIQSLGTGCGAWIGGMLLATTANGQIAGYGTNGWLSVGMVVFTLIWVGQVQPAKEPEQSSIATKLSVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5I6</accession>
    <name>A0A2S9H5I6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0413</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95218">
        <property type="protein sequence ID" value="PRC95218"/>
        <property type="gene ID" value="S2091_0413"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="7"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC95218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="302" mass="33561" checksum="4780312C14B28E2D" modified="2018-07-18" version="1">MSLPGQIDLNDLVIFDAVVESGGFTAAAERLGVAGAKVSLEIGRLEASLGTRLFTRTTRKVILTDAGLSLHQECQPLLRGLQEALNQYGSVKTELIGTLRISTTVDHATQSLGAALAQFSALHPKLQIDLRTGDRVLDLVGEGVDLAIRIGWLRDSSMHALKLGEFEQYMVASPEYLRRNKVPKHPEQLAELDWVALTLMKTPLTWQFTSKAGEEVQIHVKSHFKVDSPNALRTVLRNHAGISVLDQRSVQQDIEEGHLKRLLPDWTLPKGGIYAVYPAGRHVPQKVRAFIDFYRNYLIQKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GS87</accession>
    <name>A0A2S9GS87_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4715</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000051">
        <property type="protein sequence ID" value="PRC90577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90577">
        <property type="protein sequence ID" value="PRC90577"/>
        <property type="gene ID" value="S2091_4715"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC90577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="64" mass="6566" checksum="EC3E9657B32FE2F7" modified="2018-07-18" version="1">MTVLPDTVQTDVVAEVNATAKLVLLVADTVKGAVPYDLPVNAANVMVCVPLVTVNDSATWGAAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GS98</accession>
    <name>A0A2S9GS98_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative nucleoside-diphosphate sugar epimerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_4707</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the polysaccharide synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000048">
        <property type="protein sequence ID" value="PRC90587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90587">
        <property type="protein sequence ID" value="PRC90587"/>
        <property type="gene ID" value="S2091_4707"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05237">
        <property type="entry name" value="UDP_invert_4-6DH_SDR_e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003869">
        <property type="entry name" value="Polysac_CapD-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02719">
        <property type="entry name" value="Polysacc_synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="15"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="47"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="80"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="110"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="domain" description="Polysacc_synt_2" evidence="3">
        <location>
            <begin position="283"/>
            <end position="576"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC90587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="652" mass="72887" checksum="0F767C5C19558996" modified="2018-07-18" version="1">MINLFLTLSRFQKQCIAACADMFFLPLMFAAALWMRFDVVNVTLLKQFLLVIIAAPIIAIPIFIRLGLYRAIIRFVEQKIVIVIMYGVTITVLSLLSLAIFLKIEILSRAVFGIFWLNAAMYMLASRFLVRSFLLKRNHNRNAIRVAIYGAGRTGVQMATALRTSQEYRPMFLIDDKKELQGTTIAGIRVYPSTDLSGLIKKNRVQEIHLVMPSISKKSQKVILDWLEKLHIKVKVTPPIRDLLKGELSVKDIREIEIEDLLGRDPVEPNPLLISACITGKTVLVSGAGGSIGSELCRQILRQKPARLIMLDTSEFALYTIEKELSSFKQSHSLAIHIMPFLGSVLDTVKCQGILTTFSVQTVYHAAAYKHVPLVEQNPIEGIRNNVFGTLSIARAAMNAGVANFVLISTDKAVRPTNVMGSTKRLAELILQAFAEKESCTRFCMVRFGNVLGSSGSVVPLFRQQIMAGGPITLTHPDITRYFMTIPEAAQLVLQAGSMGEGGDVFVLDMGEPVKIIDLAKRMVRLSGLLLKSESLDNKAIDIQHVGLRPGEKLYEELLIGENVDGTDHPLIMRAQENRISWLILQQILDKLDAACRSFAYEEVRALLLEAVREYQPQCGIEDMVWSEQLKQQQHQTQALNQHPFQGGHLLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSE4</accession>
    <name>A0A2S9GSE4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4669</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000042">
        <property type="protein sequence ID" value="PRC90633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90633">
        <property type="protein sequence ID" value="PRC90633"/>
        <property type="gene ID" value="S2091_4669"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015075">
        <property type="entry name" value="AtaL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08982">
        <property type="entry name" value="DUF1857"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC90633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="160" mass="18774" checksum="660E110E093D4151" modified="2018-07-18" version="1">MKFEHLIEINDLNNPFVPMMTREQLWNGLVLRAEFPKLFVSYLDACNITSRDLDSLTRTLQFGDLKVNDHVHFNFLNFVHYQVHQQGEIPESSMRMTIEEPASQALFVRFSYDDGHTKAEDIENATYNEYRRSAYVEADIETVKILREMHDNGRLDSLLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSK8</accession>
    <name>A0A2S9GSK8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">ABC-type proline/glycine betaine transport systems periplasmic component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_4597</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000038">
        <property type="protein sequence ID" value="PRC90704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90704">
        <property type="protein sequence ID" value="PRC90704"/>
        <property type="gene ID" value="S2091_4597"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007210">
        <property type="entry name" value="ABC_Gly_betaine_transp_sub-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04069">
        <property type="entry name" value="OpuAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015671990" evidence="2">
        <location>
            <begin position="32"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="domain" description="OpuAC" evidence="3">
        <location>
            <begin position="42"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC90704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="342" mass="37455" checksum="C159649CEB9015DF" modified="2018-07-18" version="1">MEKYMLKKTNKWLVGLALFAVVCLMSVTSMAAEFAAPGNGVKVTPIKSSLAEETFQAELVIRALRDLGYDVNPIQEVDYAVGYIALASGNATFLANNWSPLHNEYFEKAGGTSKLYRQGMFAEGAVQGYLIDKKTADKYHITNLAQLRDPQIAKLFDSSGNGKADLAGCDPGWGCAKVIEHQLDAYDLRNTVTNNSGNYAAIIADTMARYKQGKPILYTTWTPYWLSAVLVPGRDVVWLEVPFSAQPDESKDVDTALPNGKNYGFALNHIQIVANLTWAKANPAAAKLFAVMKLPLSDISAQNAAMAKGQNKPTDINRHVSGWIKAHQATYDEWLKQARAAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSR3</accession>
    <name>A0A2S9GSR3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NAD dependent epimerase/dehydratase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4510</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000036">
        <property type="protein sequence ID" value="PRC90762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90762">
        <property type="protein sequence ID" value="PRC90762"/>
        <property type="gene ID" value="S2091_4510"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="1">
        <location>
            <begin position="4"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="321" mass="35093" checksum="2FC2ED65826A54C1" modified="2018-07-18" version="1">MKRILVIGANGQIGSELVDALAAEYGAENVIASDIAPHSMYGAAHYQTLDVLDAERMAHVVAQYQITDVYQLAALLSVTGEQAPLKAWTLNMDGLLNILELARIRGEAGKPLQVFWPSSIAAFGPNTPAVNTPQMTVMDPTTIYGISKLAGERLCEYYFNKYGVDVRSIRYPGIISYKSPPGGGTTDYAIAIFHAALRGESYDCFLSADTALPMIYMPDAIRATIELMQAPAEKIKIRSAYNVAGISFTPEQIATEIQSHYPNFGVNYRPDHRQAIANTWPDSLDDQQASGDWAWQAKISLPAMVADMLKNIVIEKDSKVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSS9</accession>
    <name>A0A2S9GSS9_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">L-serine dehydratase</fullName>
            <ecNumber evidence="9">4.3.1.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">S2091_4509</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>L-serine = NH4(+) + pyruvate</text>
            <dbReference type="Rhea" id="RHEA:19169"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="EC" id="4.3.1.17"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 9">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the iron-sulfur dependent L-serine dehydratase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.3.1.17" evidence="9"/>
    <dbReference type="EMBL" id="PUGF01000036">
        <property type="protein sequence ID" value="PRC90761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90761">
        <property type="protein sequence ID" value="PRC90761"/>
        <property type="gene ID" value="S2091_4509"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003941">
        <property type="term" value="F:L-serine ammonia-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029009">
        <property type="entry name" value="ASB_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004644">
        <property type="entry name" value="Fe-S_L-Ser_mono"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005130">
        <property type="entry name" value="Ser_deHydtase-like_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005131">
        <property type="entry name" value="Ser_deHydtase_bsu"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03313">
        <property type="entry name" value="SDH_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03315">
        <property type="entry name" value="SDH_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143548">
        <property type="entry name" value="SSF143548"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00720">
        <property type="entry name" value="sda_mono"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="9" id="KW-0312">Gluconeogenesis</keyword>
    <keyword evidence="6 9" id="KW-0408">Iron</keyword>
    <keyword evidence="7 9" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="8 9 12" id="KW-0456">Lyase</keyword>
    <keyword evidence="5 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SDH_beta" evidence="11">
        <location>
            <begin position="5"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="domain" description="SDH_alpha" evidence="10">
        <location>
            <begin position="184"/>
            <end position="446"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU366059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF03313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF03315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PRC90761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="457" mass="48361" checksum="5F739B3F872D7435" modified="2018-07-18" version="1">MDMRVFDLFKIGVGPSSSHTVGPMLAARRFLLECADLAQVNHVEVALYGSLALTGVGHATDKAVLLGLLGETPQDVVPETMDAKIAEIVASKKLSLLGEYRISFNVATDLLWHKQESLPGHPNGLKFTATRRDGSVTSQIFYSTGGGFIQSEHELGHEPAVAPITKPFPFGSMDELLAHGERSGLSLVAMMRANEAVYEGDAELNARLDTIWHVMRDCIETGLREEGILPGGLMVKRRAAKLWRAAQENAASLPHDPIHKVSLYAMAVNEVNAAGGRVVTAPTNGAAGIIPAILRYYAQDCQQIDPENGVRDFLLVASAVGMLCKKNASISGAEIGCQGEVGVACAMAAAGLTAALGGTNQQIEAAAEIGIEHHLGMTCDPIGGLVQIPCIERNGMGAVKAITAASLALHSDGTHHVSLDQVIETMRHTGFDMQAKYKETSLGGLAIHVVTVNHAAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSW1</accession>
    <name>A0A2S9GSW1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4463</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000035">
        <property type="protein sequence ID" value="PRC90800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90800">
        <property type="protein sequence ID" value="PRC90800"/>
        <property type="gene ID" value="S2091_4463"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC90800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="70" mass="8143" checksum="DD41F79398F05353" modified="2018-07-18" version="1">MAEEILFAFKNTFYIKIPSSQMTVFLFVSMIKREYLGSRITILKSITPLLKNENLIVTISKMLDATRRIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GT39</accession>
    <name>A0A2S9GT39_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">FAD binding domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4385</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000033">
        <property type="protein sequence ID" value="PRC90892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90892">
        <property type="protein sequence ID" value="PRC90892"/>
        <property type="gene ID" value="S2091_4385"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD_binding_3" evidence="1">
        <location>
            <begin position="25"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="569" mass="63921" checksum="308EA0FC439321B6" modified="2018-07-18" version="1">MNKDYQSLTFTYQPRQAKRDVKVHPVVVVGAGPVGLSAAIALAQQGIAVVLVDDDHTLSTGSRAICFAQHTLDIFNRLGCGEQMTNKGVSWNTGKIFFKDQQVYSFNLLPKSGHQQPAFINLQQYYVEGYLVERALKLPLIDLRWKNKVVDLQQDAHCTNLTIATPDGNYTLRAQYVIAADGAHSSVRRIMGLDSVGRTFKDRFLIADIKMHAPFPSERWFWFDPPFHPNQSVLLHRQPDNMWRIDFQLGWDADPTVETKPENVIPRIWALLGHEAKFELEWVSVYTFSCLRMEKFRHDRVLFAGDAAHRVSPFGARGANSGVQDADNVAWKLALVLKGLASDNLLDSYAEERELAADENILCSTRSTDFITPKSPVSRFFRDAVLQLSNKTLFARQLVNSGRLSTPSVLLQSSLTTPDSDVFATELMPGSVAVDAPVRINGNSDWLLAQLRHEFTGVYFHTGCVTDLNAQTVSQLNDLQNGLIPFQIILIKMDDPLSSFNIDAHLNSSSAQLTNFVILEDVDHLAAQRYDAEDATFYLIRPDQHICARWRQFDVALVEQALQKACGIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GT55</accession>
    <name>A0A2S9GT55_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_4374</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000033">
        <property type="protein sequence ID" value="PRC90881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90881">
        <property type="protein sequence ID" value="PRC90881"/>
        <property type="gene ID" value="S2091_4374"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="125"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="269"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="314"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="343"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC90881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="367" mass="40181" checksum="E2E2D31FB4930718" modified="2018-07-18" version="1">MEIDSPTNVTKPSEANEVGLPSDAEKVALGQSGPLIRFAAENVTDLDKALVVAIAKARQAQIEKTWSPTTSEEFWSAFNALCSLIKPVTVDGLSAEHRNIPLRFRIRFWRAPINESLGERSSRRYTVGLLALLGIIVGFQLITWIYTNLSDDLDKKAKTLQVSSVDLRAKCDLLAPKMLGKDGKQHEWTDGETASYNNIIHDIDALNLESTRLYASGEFLTEILPRFKNSSGSLQSGDLSDWINRCDTAQQNVIITSTLASLASDRARLFSGILLQFLLPVFLGSIGALAYVLRFTSEQIKSTTFTTTSPVRNLVRIALGALMGVVIGLFTDLSTKANLQPLALAFLAGYGVEPVFSLFDGLIARLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GT69</accession>
    <name>A0A2S9GT69_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Pro-kumamolisin, activation domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_4398</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000033">
        <property type="protein sequence ID" value="PRC90905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90905">
        <property type="protein sequence ID" value="PRC90905"/>
        <property type="gene ID" value="S2091_4398"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04056">
        <property type="entry name" value="Peptidases_S53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11377">
        <property type="entry name" value="Pro-peptidase_S53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015366">
        <property type="entry name" value="S53_propep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030400">
        <property type="entry name" value="Sedolisin_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09286">
        <property type="entry name" value="Pro-kuma_activ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00944">
        <property type="entry name" value="Pro-kuma_activ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="SSF52743"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51695">
        <property type="entry name" value="SEDOLISIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0106">Calcium</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0720">Serine protease</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5016273887" evidence="5">
        <location>
            <begin position="29"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S53" evidence="6">
        <location>
            <begin position="212"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="4">
        <location>
            <position position="284"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="4">
        <location>
            <position position="288"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="4">
        <location>
            <position position="536"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC90905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="619" mass="65698" checksum="2D3037F1401245D6" modified="2018-07-18" version="1">MKLRTKPLAALVSGLFVGALWSSSGAFAATVSATAQDLGATAPTQTQTVSIVLQLRNVDHLTDFIAATVNPNSNRYHQFLSVDDFARHYAPTDADIGRVTAALNQLGIQVNEVYKNHMIIRATGTTAQLNQFFNTEVHNYKENTTLYSKPNRKVSIPDSVADVVLTVTGLDTKPKAHPMSRNLAKATGGALSINANSVKLLNGVTTANAPGLFTVADVASLYNINPLYEHHILGQGRAVGIATLATFTPSDAYTYWQSVGLKVSPNKIVQVHVDGGAGTNGSGETTLDVEQSGGLAPASKVFVYDAPNTDAGFIDVFFKAASDNIVDTLSTSWGEPEIAQDSDVLAGQHQAFLELAAQGITMFAAAGDEGAYDINDNQGPYAYPGCSQLLSVDSPASDPFVVAAGGLTLAGVQTFPNASITVPKDRPWAWDYLQNYIETYYGSAVYYADVFPVGGGGGVSVNYPLPRYQKYISGTQVSAANQSLICQSPTGPQDLVDLPAGYVGRNVPDLSLNADPDTGYALYVGGAWQYGWGGTSFVAPQLNGITALLSQFSGTRLGHLNPQLYALLQQYGYSHNSPFRAITSGDNEYWQATHSYNPASGIGALDVTNLARTLSGWGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GT89</accession>
    <name>A0A2S9GT89_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative enzyme of the cupin superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4335</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000032">
        <property type="protein sequence ID" value="PRC90934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90934">
        <property type="protein sequence ID" value="PRC90934"/>
        <property type="gene ID" value="S2091_4335"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008579">
        <property type="entry name" value="UGlyAH_Cupin_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05899">
        <property type="entry name" value="Cupin_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cupin_3" evidence="1">
        <location>
            <begin position="49"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="123" mass="13843" checksum="737447A4F487CB4D" modified="2018-07-18" version="1">MSEFQSSAPHLVDVSTRTDLLNWGRQPNSIEDEFKAESHSSGRLIHKGPDNQPEVGLWVCTPGRWHLSIPRDELCYFVAGRATYAHLNGEVIEVMASTLVMFTAGWQGECTVHETIRNSYILL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTD2</accession>
    <name>A0A2S9GTD2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phage baseplate assembly protein W</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4270</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000031">
        <property type="protein sequence ID" value="PRC90974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90974">
        <property type="protein sequence ID" value="PRC90974"/>
        <property type="gene ID" value="S2091_4270"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007048">
        <property type="entry name" value="IraD/Gp25-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04965">
        <property type="entry name" value="GPW_gp25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GPW_gp25" evidence="1">
        <location>
            <begin position="14"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="117" mass="12831" checksum="0517F20979806717" modified="2018-07-18" version="1">MIGMNALTGRALSGLAHIRQSLADILTTPLGSRVMRRDYGSEVPELIDQPLNSVTQLRLYAATAYAVQRWEPRIRLTSLQLDYNAAGRASLSLQGITEQQSVELTVPLNSDQHQVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTE7</accession>
    <name>A0A2S9GTE7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4290</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000031">
        <property type="protein sequence ID" value="PRC90994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90994">
        <property type="protein sequence ID" value="PRC90994"/>
        <property type="gene ID" value="S2091_4290"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC90994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="55" mass="6496" checksum="996CC3FFF857BD8E" modified="2018-07-18" version="1">MQLPLSIRITSPSLFRVILREYVFCKQERFFWSVSLLSFDLQNFLHEAGGMAGEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTG1</accession>
    <name>A0A2S9GTG1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4296</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000031">
        <property type="protein sequence ID" value="PRC91000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91000">
        <property type="protein sequence ID" value="PRC91000"/>
        <property type="gene ID" value="S2091_4296"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="76"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="242" mass="27177" checksum="68C44E0C15D3293A" modified="2018-07-18" version="1">MKMNRFQASALHLFGSACFLAVFFLMVSQVWYPGKLFSAAAGVELLRLLICVDLIIGPLVTLIIFNPQKKKLKQDLIIVVLCQLGFLFYGVWSIYTVRPVYIAFAENKFYMVRANEIDATDQAKVTDTHFKSLPVFGPEYVGTQEPTDPKIKNDIVFSSLAGMGIQNLPQYFVPLNKIQQQIKAAAKTSQEWKTIDAETKQRLKSYERENAGTSVSFIALINKRIALFVVINAQTGEIIGII</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTH4</accession>
    <name>A0A2S9GTH4_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase</fullName>
            <ecNumber evidence="3">2.7.6.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">S2091_4313</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; tetrahydrofolate biosynthesis; 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate from 7,8-dihydroneopterin triphosphate: step 4/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the HPPK family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.6.3" evidence="3"/>
    <dbReference type="EMBL" id="PUGF01000031">
        <property type="protein sequence ID" value="PRC91017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91017">
        <property type="protein sequence ID" value="PRC91017"/>
        <property type="gene ID" value="S2091_4313"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00077">
        <property type="reaction ID" value="UER00155"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003848">
        <property type="term" value="F:2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046656">
        <property type="term" value="P:folic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046654">
        <property type="term" value="P:tetrahydrofolate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00483">
        <property type="entry name" value="HPPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.560">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000550">
        <property type="entry name" value="Hppk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035907">
        <property type="entry name" value="Hppk_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01288">
        <property type="entry name" value="HPPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55083">
        <property type="entry name" value="SSF55083"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01498">
        <property type="entry name" value="folK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0289">Folate biosynthesis</keyword>
    <keyword evidence="7 14" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HPPK" evidence="13">
        <location>
            <begin position="9"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00029409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00029766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00033413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="PRC91017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="162" mass="17626" checksum="8B7DB5D0EAFE378A" modified="2018-07-18" version="1">MKQAEGIAYIGLGANLGDPQDSINAAIVALGALPSTRLTQASSLYTSAPMDADGDDYVNAVVELHTQLSPTELLSELQNLEQQFGRIRSYQNAPRTLDLDLLLYEQLTINTATLQVPHPRMTQRAFVMVPLLEISPEINIPDFGSAHTLLPALCDQVIQKIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTI8</accession>
    <name>A0A2S9GTI8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4227</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000030">
        <property type="protein sequence ID" value="PRC91039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91039">
        <property type="protein sequence ID" value="PRC91039"/>
        <property type="gene ID" value="S2091_4227"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="70" mass="8045" checksum="7F17BD4B452971E5" modified="2018-07-18" version="1">METVESLLNQLPFSYKDRSSFFQLGVVNAAEKIIHQKFITSGWKDLLLGSPELDAFDFAFDKALLFFLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GU89</accession>
    <name>A0A2S9GU89_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 6">Glutamine-dependent NAD(+) synthetase</fullName>
            <ecNumber evidence="5 6">6.3.5.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5 6">NAD(+) synthase [glutamine-hydrolyzing]</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">nadE</name>
        <name evidence="9" type="ORF">S2091_4059</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>ATP + deamido-NAD(+) + H2O + L-glutamine = AMP + diphosphate + H(+) + L-glutamate + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:24384"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:58437"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.5.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 5 6">Cofactor biosynthesis; NAD(+) biosynthesis; NAD(+) from deamido-NAD(+) (L-Gln route): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the NAD synthetase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 5 6">In the C-terminal section; belongs to the NAD synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.1" evidence="5 6"/>
    <dbReference type="EMBL" id="PUGF01000026">
        <property type="protein sequence ID" value="PRC91274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91274">
        <property type="protein sequence ID" value="PRC91274"/>
        <property type="gene ID" value="S2091_4059"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00253">
        <property type="reaction ID" value="UER00334"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004359">
        <property type="term" value="F:glutaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003952">
        <property type="term" value="F:NAD+ synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008795">
        <property type="term" value="F:NAD+ synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009435">
        <property type="term" value="P:NAD biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00553">
        <property type="entry name" value="NAD_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02090">
        <property type="entry name" value="NadE_glutamine_dep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003010">
        <property type="entry name" value="C-N_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036526">
        <property type="entry name" value="C-N_Hydrolase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014445">
        <property type="entry name" value="Gln-dep_NAD_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022310">
        <property type="entry name" value="NAD/GMP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003694">
        <property type="entry name" value="NAD_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23090">
        <property type="entry name" value="PTHR23090"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00795">
        <property type="entry name" value="CN_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02540">
        <property type="entry name" value="NAD_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006630">
        <property type="entry name" value="NADS_GAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56317">
        <property type="entry name" value="SSF56317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00552">
        <property type="entry name" value="nadE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50263">
        <property type="entry name" value="CN_HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 6 7" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 6 7" id="KW-0520">NAD</keyword>
    <keyword evidence="3 5 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CN hydrolase" evidence="8">
        <location>
            <begin position="2"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; for glutaminase activity" evidence="5">
        <location>
            <position position="42"/>
        </location>
    </feature>
    <feature type="active site" description="For glutaminase activity" evidence="5">
        <location>
            <position position="112"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile; for glutaminase activity" evidence="5">
        <location>
            <position position="148"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="174"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="180"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="285"/>
            <end position="292"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="368"/>
        </location>
        <ligand>
            <name>deamido-NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58437"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="392"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="397"/>
        </location>
        <ligand>
            <name>deamido-NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58437"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="507"/>
        </location>
        <ligand>
            <name>deamido-NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58437"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR006630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC91274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="536" mass="59213" checksum="CB78C58A6BBE6409" modified="2018-07-18" version="1">MIKLAVVQMNSTLGDLSGNAAHILNFSRRAYQQGAHIVLTPELSLVGYPPEDLLLRDSFYSASQAALNELATQLAEFPNLHVLVGHPLMKDGRRYNAASLLVNGRIQASYCKQDLPNGHVFDEKRYFDAGQDALVFEFENVKFGVTICEDTWSAAVPTQAKIAGAQVLLVLNGSPFHMNKQHLRYQVMRDNVTQQGMALVYANLVGGQDELIFDGNSFVLDSQGQIQAQLKHAQEDLQIIEFAGATPQAGVIAPELSVEAQVYQALVLGVRDYIGKNGFPSVLLGMSGGVDSALTLAIAVDALGADKVRAVMMPSPYTAEISWLDSREMVDKLGVRYDEISINPCFSAFTATLAQEFEGLPLDATEENIQARIRGTLLMALSNKHGSIVLTTGNKSEMAVGYCTLYGDMAGGFAVLKDIAKTLVYRLCAYRNSLSLVIPERILTRPPSAELRPDQTDQDSLPPYEILDGIMQMHMEENCSTEQIVKAGYQQQDVDRITRLIKINEYKRRQSPVGIRVTHRAFGRDWRYPITSKFRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUP0</accession>
    <name>A0A2S9GUP0_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Probable fimbrial chaperone EcpB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_3862</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the EcpB/EcpE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000023">
        <property type="protein sequence ID" value="PRC91447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91447">
        <property type="protein sequence ID" value="PRC91447"/>
        <property type="gene ID" value="S2091_3862"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040695">
        <property type="entry name" value="EcpB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008962">
        <property type="entry name" value="PapD-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18649">
        <property type="entry name" value="EcpB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49354">
        <property type="entry name" value="SSF49354"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1029">Fimbrium biogenesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015724204" description="Probable fimbrial chaperone EcpB" evidence="4">
        <location>
            <begin position="22"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="domain" description="EcpB_C" evidence="5">
        <location>
            <begin position="156"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00014241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF18649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC91447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="225" mass="24473" checksum="337C619D4AD7D9C6" modified="2018-07-18" version="1">MSKKPFLVSVLLWVCASGAYAINVGVLTTEIQDTEFFVVKEIKNQESVAKFVTTKVIEVDNPKSLAPVLGGAPDVLVSPATLLVGPKKSASVKIYYNGAKDDRERYYQLIFVEQSMSKATDLTAKASIEAKQKISIATILVARPRVLDFKYEVDGKGAIKNVGNSFMQTVAIGQCAGDTADGLTPCASEEFILPGERVDFSKKFKVFDGYGIWHGLKYEFIAGGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GV43</accession>
    <name>A0A2S9GV43_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein conserved in bacteria (DUF2147)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3705</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000021">
        <property type="protein sequence ID" value="PRC91589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91589">
        <property type="protein sequence ID" value="PRC91589"/>
        <property type="gene ID" value="S2091_3705"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019223">
        <property type="entry name" value="DUF2147"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09917">
        <property type="entry name" value="DUF2147"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015629885" evidence="1">
        <location>
            <begin position="25"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="domain" description="DUF2147" evidence="2">
        <location>
            <begin position="30"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="150" mass="16559" checksum="1CE6091B5EF40469" modified="2018-07-18" version="1">MTHKKISTVVIGVLAAFISFAVCAQDSPVGLWKNIDDVTGKPKALIRITENNGELTGKIEKLFKEANEDQNPKCDKCEGANKDQPVIGMVILKGLKKDDDEYNGGTILDPANGKIYKSKLVLEEGAKKLNVRGYIGFPWLGRSQVWVREQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GV97</accession>
    <name>A0A2S9GV97_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_3747</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000021">
        <property type="protein sequence ID" value="PRC91631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91631">
        <property type="protein sequence ID" value="PRC91631"/>
        <property type="gene ID" value="S2091_3747"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016054">
        <property type="term" value="P:organic acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002204">
        <property type="entry name" value="3-OH-isobutyrate_DH-rel_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006115">
        <property type="entry name" value="6PGDH_NADP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015815">
        <property type="entry name" value="HIBADH-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029154">
        <property type="entry name" value="NADP-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14833">
        <property type="entry name" value="NAD_binding_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03446">
        <property type="entry name" value="NAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000103">
        <property type="entry name" value="HIBADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00895">
        <property type="entry name" value="3_HYDROXYISOBUT_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0520">NAD</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD_binding_2" evidence="4">
        <location>
            <begin position="10"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="domain" description="NAD_binding_11" evidence="5">
        <location>
            <begin position="167"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000103-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF14833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC91631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="304" mass="31795" checksum="D29ADB55ECF704EF" modified="2018-07-18" version="1">MKNSAALPHIAFLGLGLMGQPMACRLLQAGYPLTVWNRTAAKAAVCVAQGATLAETIPEAVRSAAIVITMLEAGPVVKQVLNQALDALADEVLVIDMSSTQQLEALELHQLLAARGVGFIDAPVSGGVIGAEAGSLAIMVGASELDYLRVKPILEVMGKPTLVGAPGSGQLAKLCNQLIVGGTLILVAEALLLAQAGGADPAAVRQALRGGFAESKILEVHGQRMLDRNFMPGGQVRSQAKDMENILLAAQQAQLKLPQAELIAQVYRHLLITNPQADHSAALLELENNNSGIRLGQKPDQLPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVD1</accession>
    <name>A0A2S9GVD1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Dehydrogenases with different specificities (Related to short-chain alcohol dehydrogenases)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3617</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000020">
        <property type="protein sequence ID" value="PRC91679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91679">
        <property type="protein sequence ID" value="PRC91679"/>
        <property type="gene ID" value="S2091_3617"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="258" mass="27672" checksum="4A3B1E26FAAE4DDD" modified="2018-07-18" version="1">MGIEVNFEGKIALVTGASSGLGARFAKVLAQAGAQVVLAARRIDRLKELRAEIEAEGGAAHMVQLDVSDYASIKSAIAHAETEAGPIDILINNAGVSTTQRLLDVTPDDYAYVMDTNQRGAFFVAQETAKRMVARAKGDPKKQHRIVNIASVAGMRALPQIGIYCMSKAAVIQMTKAMALEWGKYGINVNAICPGYIATEINQSYFDSEAGRKLMSMLPRNRLGQPEDLDGLLLLLAAEESRFLNGAIVSADDGMSIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVG8</accession>
    <name>A0A2S9GVG8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Carbon starvation protein predicted membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">S2091_3657</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000020">
        <property type="protein sequence ID" value="PRC91719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91719">
        <property type="protein sequence ID" value="PRC91719"/>
        <property type="gene ID" value="S2091_3657"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009267">
        <property type="term" value="P:cellular response to starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025299">
        <property type="entry name" value="CstA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003706">
        <property type="entry name" value="CstA_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02554">
        <property type="entry name" value="CstA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13722">
        <property type="entry name" value="CstA_5TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="32"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="93"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="119"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="161"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="189"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="221"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="256"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="284"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="322"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="362"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="463"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="510"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="541"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="573"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="642"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="domain" description="CstA" evidence="9">
        <location>
            <begin position="32"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="domain" description="CstA_5TM" evidence="10">
        <location>
            <begin position="463"/>
            <end position="591"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF13722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC91719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="686" mass="73640" checksum="EF2F5388C870E7FD" modified="2018-07-18" version="1">MKQISSHIGWLLLALVGAFALGYVALNRGETINALWIIVAAVSVYLISYRYYSRFIADKVLGIDPTRKTPAYKHNDGLDYVPTNKYVLFGHHFAAIAGAGPLVGPVLAAQMGYLPGMLWILAGVVLAGAVQDFMVLFVSVRRDGRSLGDLIKSELGTVPGVIALFGCFLIMIIILAVLALIVVKALTHSPWGTFTVGATIPIALMMGLYMRYVRPGRIGEISIVGFILLMLAIYFGGVVAADPVWSAMFNFDGKQLTWALVVYGFVAAVIPVWLLLAPRDYLSTFLKIGTIVGLAVGVLFVAPELKMPAITRFVDGSGPVWAGSLFPFLFITIACGAVSGFHALISSGTTPKMLENESQARFIGYGGMLMESFVAIMALVAASVIDPGVYFAMNSPAAVIGTTPEAVAAVVSSWGFVITPDVLIQTTKDIGETTILSRAGGAPTLAVGMAHILHQFIGGQKMMAFWYHFAILFEALFILTAVDAGTRAGRFMLQDLLGTFIPSLKRTDSLPANLIATGVCVSLWGYFLYQGVVDPLGGINTLWPLFGIANQMLAAIALTMCAAILFKMKRQRYAWVAIVPTLILLTCTLTAGWIKVFDSNPKLGFLALANKFATGLENGVLIAPAKSAEEMSRLVFNNRLDAGLTLLFMFVVVSVVGFGLRTAFQSLKSDQPTSNETPYEAMTSVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVJ6</accession>
    <name>A0A2S9GVJ6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GMP synthase-Glutamine amidotransferase domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3502</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000019">
        <property type="protein sequence ID" value="PRC91747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91747">
        <property type="protein sequence ID" value="PRC91747"/>
        <property type="gene ID" value="S2091_3502"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01741">
        <property type="entry name" value="GATase1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044992">
        <property type="entry name" value="ChyE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42695">
        <property type="entry name" value="PTHR42695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GATase" evidence="1">
        <location>
            <begin position="46"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="239" mass="26458" checksum="DFE70825DFFF21CC" modified="2018-07-18" version="1">MKPVLIIQQVVLDTADYFIDFLATQNIPFELRQMHAGELPPASIFGYSGYCMLGGPMSVNDEENFPYLRQQKALVREALAAGVPMIGHCLGGQLMSTALGGTVTTTALPEIGWSSIQVTDTQAAQDWFGGHSTFDMFQWHNETFSIPHGAKLIASSAHCPHQAFIIGDKHIAMQFHCEVKHSKVRHWAIEEKADIDALQHLASVQSSDSIVETLNQRIPASNAMAHIIYSRWIRSLTDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GW13</accession>
    <name>A0A2S9GW13_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Type IV pilus biogenesis/stability protein PilW</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3473</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000018">
        <property type="protein sequence ID" value="PRC91917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91917">
        <property type="protein sequence ID" value="PRC91917"/>
        <property type="gene ID" value="S2091_3473"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013360">
        <property type="entry name" value="Pilus_4_PilW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02521">
        <property type="entry name" value="type_IV_pilW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015667641" evidence="2">
        <location>
            <begin position="21"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="48"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="82"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="266" mass="30424" checksum="FA5686153CAF2D14" modified="2018-07-18" version="1">MRNFWRRICFCVILSGILTACTTTYDAPKLGSPSVNDGQVQGSDAKRAAIRLQLGISYLQQDQFPVALKELNNAISIDPTLADAYGVRAVVYMQMQENNLAEQDFLRVMKLAPNNPDHTSNYAWFLCQNGKEKQAMDMFDRVIKDRTYTQPVKALNNAGLCSLKMKDDVLAESYFAQALRFDVNNATTNLNLAHLSYKKQDWTRGQFYVNRLIKVEAYTPEVLWLAIKIDHKLNDLISESSLVVQLRRRFPESDEYAKFQRGAFDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GW28</accession>
    <name>A0A2S9GW28_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7 9">GTPase Der</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">GTP-binding protein EngA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">der</name>
        <name evidence="11" type="ORF">S2091_3467</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7 9">GTPase that plays an essential role in the late steps of ribosome biogenesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Associates with the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7 8 9">Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000018">
        <property type="protein sequence ID" value="PRC91911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91911">
        <property type="protein sequence ID" value="PRC91911"/>
        <property type="gene ID" value="S2091_3467"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00195">
        <property type="entry name" value="GTPase_Der"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031166">
        <property type="entry name" value="G_ENGA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016484">
        <property type="entry name" value="GTP-bd_EngA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032859">
        <property type="entry name" value="KH_dom-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14714">
        <property type="entry name" value="KH_dom-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006485">
        <property type="entry name" value="GTP-binding_EngA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03594">
        <property type="entry name" value="GTPase_EngA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51712">
        <property type="entry name" value="G_ENGA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 9" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5 7 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 7" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="EngA-type G" evidence="10">
        <location>
            <begin position="9"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="domain" description="EngA-type G" evidence="10">
        <location>
            <begin position="186"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="15"/>
            <end position="22"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="62"/>
            <end position="66"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="125"/>
            <end position="128"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="192"/>
            <end position="199"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="239"/>
            <end position="243"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="304"/>
            <end position="307"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00020953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51712"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC91911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="452" mass="49882" checksum="C7B11225D1F83C36" modified="2018-07-18" version="1">MRLIDLMKPVIALIGRPNVGKSTLFNRLTRSRDALVADMPGLTRDRHYGEGRVGDRPFLVIDTGGFEPVAKEGIMYEMAKQTKQAVAEADVVIFIVDGRQGLTPHDKTITDFLRKSGRSVMLVVNKAEGMKYTSVTADFYELGLGDPYVISAAHGDGVSDLVIEALDIAFSQRTEEEEPDSQDRGIKLAIVGRPNVGKSTLVNALLGEERVIAFDMPGTTRDSIEIAFERDGQNYTLIDTAGIRKRGKVFEAIEKFSVVKTLQSISEANVVLLLLDAQQDISEQDAHIAGFILESGRALVVGVNKWDGLQSDRRDEIKSDIERKLGFLSFAKFHFISALKTSGIAPMMKSVIQAYAAATANLSTPKLTRALIEAVEHQQPKRKGSIRPKLRYAHQGGQNPPIIVIHGNALDGVGDVYKRYLEKHFRETFSLVGTPLRIEMKSSKNPFSKTEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWF7</accession>
    <name>A0A2S9GWF7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Dehydrogenases with different specificities (Related to short-chain alcohol dehydrogenases)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3202</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000016">
        <property type="protein sequence ID" value="PRC92067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92067">
        <property type="protein sequence ID" value="PRC92067"/>
        <property type="gene ID" value="S2091_3202"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="252" mass="26173" checksum="2A17D6391A2D9080" modified="2018-07-18" version="1">MQIQDNVFIVTGGASGLGAATARMITANGGKVVIADVQAALGEKLAAELNGRFVQCDVTSEADGLAVIAAATAFGTLRGLINCAGVAPAIKTVGKDGAHPLEAFQRTVNINLVGTFNMCRLAAEAISKTELTSQGERGVLINTASVAAFDGQMGQAAYASSKAAVVGLTLPMARDLARNAIRVMTIAPGIFETPMLLGMPQEVQDALGRSVPFPSRLGKPDEYAQLAKSIIENMMLNGESIRLDGSIRMQPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWL4</accession>
    <name>A0A2S9GWL4_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">EVE domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3239</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000016">
        <property type="protein sequence ID" value="PRC92104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92104">
        <property type="protein sequence ID" value="PRC92104"/>
        <property type="gene ID" value="S2091_3239"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002740">
        <property type="entry name" value="EVE_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01878">
        <property type="entry name" value="EVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="SSF88697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EVE" evidence="1">
        <location>
            <begin position="2"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="152" mass="17223" checksum="7C50CA6A24940279" modified="2018-07-18" version="1">MRYWLMKSEPDDVSIDDALAQQVVAWVGVRNYQARNFMRDLMQVGDGVLFYHSSCAEPGIAGLAEVASTSYPDPSQFDPKSPYFDPKAKPEQPRWMLVDVRAKRKTPLINLAQLRSEPELAEMVVLKRGNRLSITPVSAAEWRMILKLADVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWL8</accession>
    <name>A0A2S9GWL8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cytochrome c551/c552</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_3245</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000016">
        <property type="protein sequence ID" value="PRC92110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92110">
        <property type="protein sequence ID" value="PRC92110"/>
        <property type="gene ID" value="S2091_3245"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002324">
        <property type="entry name" value="Cyt_c_ID"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00034">
        <property type="entry name" value="Cytochrom_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00606">
        <property type="entry name" value="CYTCHROMECID"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0349">Heme</keyword>
    <keyword evidence="3 4" id="KW-0408">Iron</keyword>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015642167" evidence="5">
        <location>
            <begin position="20"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="6">
        <location>
            <begin position="15"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC92110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="100" mass="10881" checksum="7E62494470B19DE3" modified="2018-07-18" version="1">MKRLLCVMLTVFASSAAMANLDLAKSKNCMSCHSVEVKLVGPSYKDVAKKYNGQKDAEDKLVQKVMNGGSGTWGAMVMPPNPQVTEAEAHILVKWILKAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWM9</accession>
    <name>A0A2S9GWM9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alkylhydroperoxidase AhpD family core domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3051</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92135">
        <property type="protein sequence ID" value="PRC92135"/>
        <property type="gene ID" value="S2091_3051"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051920">
        <property type="term" value="F:peroxiredoxin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029032">
        <property type="entry name" value="AhpD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004675">
        <property type="entry name" value="AhpD_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003779">
        <property type="entry name" value="CMD-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02627">
        <property type="entry name" value="CMD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69118">
        <property type="entry name" value="SSF69118"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00778">
        <property type="entry name" value="ahpD_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CMD" evidence="1">
        <location>
            <begin position="28"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="170" mass="18438" checksum="C8C25BE9B3FB3BF9" modified="2018-07-18" version="1">MSLTNSTSSPVSNAHNRLSRDGFNDIAPAVNKALYAMGKAIDDSGLEKELSELIKLRASQINGCAFCVQYHLNVARELRIPQTKLDLIAVWQEAGVFSAREMAAFAWTETLTNIAGNGVSESAYAVVKLQFSDAELPFLTAAVTAINSWNRIAVAFNYAPPAPVFSNKIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWR6</accession>
    <name>A0A2S9GWR6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Reverse transcriptase (RNA-dependent DNA polymerase)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3083</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92167">
        <property type="protein sequence ID" value="PRC92167"/>
        <property type="gene ID" value="S2091_3083"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003964">
        <property type="term" value="F:RNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030931">
        <property type="entry name" value="Group_II_RT_mat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013597">
        <property type="entry name" value="Mat_intron_G2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000123">
        <property type="entry name" value="Reverse_transcriptase_msDNA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000477">
        <property type="entry name" value="RT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08388">
        <property type="entry name" value="GIIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00078">
        <property type="entry name" value="RVT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00866">
        <property type="entry name" value="RNADNAPOLMS"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="SSF56672"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04416">
        <property type="entry name" value="group_II_RT_mat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50878">
        <property type="entry name" value="RT_POL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0695">RNA-directed DNA polymerase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Reverse transcriptase" evidence="1">
        <location>
            <begin position="49"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="413" mass="48548" checksum="77EF8340D3FAE212" modified="2018-07-18" version="1">MKQVKPFVISKREVWQAYKQVKANRGAAGVDGETIDQFEQDLSKNLYRLWNRLSSGSYLPRPVRRVEIPKSDGKTRPLGIPTVADRIAQMVVKNILEPQLEPIFHRNSYGYRPNRSAHEAVGCVRQRCRNIDWVVDLDIKGFFDNIDHELLMRAVRKHTDCRWVLLYIERWLTAPVQMPDGSLVTNTGKGTPQGGVISPLLANLFLHYAFDRWMDKHFPDLPFARYADDVICHCFSKTQANMLRRAVQKRLAECKLELHPDKTKIVYCKDEARRGRHPVYKFDFLGFEFRPRWVRNRQRGTIFARFTPAVSPKACKTMRQTIRSWRLHLQTGSSLDEVVQRIRPILNGWIQYYGRFNRGLLINALATINLYLVRWAMRKYKRLRYSYAKGWQWMMRLCARQPDLLPIWLPSQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWY6</accession>
    <name>A0A2S9GWY6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glyoxalase-like domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3092</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92176">
        <property type="protein sequence ID" value="PRC92176"/>
        <property type="gene ID" value="S2091_3092"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025870">
        <property type="entry name" value="Glyoxalase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12681">
        <property type="entry name" value="Glyoxalase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="2"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="129" mass="14010" checksum="7EB861B992484E1C" modified="2018-07-18" version="1">MKFGYTIIYVTSVPDTLKFYKEAFGFETRFLHESEMYGELETGATVLAFGAHQMGEMNLDGHYQKVVATGAPFGVELAFVTEDVNAAFTKAVAAGAVAIKEPAQKPWGQQVAYVRSAEGSLIELCSPMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GX25</accession>
    <name>A0A2S9GX25_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein conserved in bacteria (DUF2191)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2932</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92273">
        <property type="protein sequence ID" value="PRC92273"/>
        <property type="gene ID" value="S2091_2932"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019239">
        <property type="entry name" value="VapB_antitoxin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09957">
        <property type="entry name" value="VapB_antitoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="65" mass="7312" checksum="07F03A7C37C8210F" modified="2018-07-18" version="1">MRTTITLDDDLLARALEISGKTERTEVLHEALRALIAREAAKRLAQLAGSMPDAQDIPRRREEMP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXM0</accession>
    <name>A0A2S9GXM0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">GGDEF: diguanylate cyclase (GGDEF) domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2839</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92464">
        <property type="protein sequence ID" value="PRC92464"/>
        <property type="gene ID" value="S2091_2839"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="41"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="68"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="97"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="121"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="151"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="191"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="2">
        <location>
            <begin position="253"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="401" mass="44060" checksum="C1C3DAD3B2AFA6CB" modified="2018-07-18" version="1">MFVNLDVRTIYLVLAVLSITQALLMFYVRQVHNNSSYVAEWARGNALVALGLCLVVVSEIVAPALLSTLSYLLIIWGTMHIAFGVALVSGKRPMRRLFQIICGIFYLAYLLAYVVGMQGVGGIVLFTIAASIFYGYSIYCCYTAQRDELRASLLLVAVMSGAYLISVYIHLLGASPADLSNPLQNSMWHSGALIVNMVLSFAQTFMLLVITSHRLQMELKQQATRDPLTNAFNRRALAKMAERDIARSNRRGTLISVLMIDADHFKNINDTFGHTIGDAVLVAMANKIQAGLRIEDILARYGGEEFLVMLPDTSLKHACEVAERIRAAIADMALPELPRQFSVSIGVAERQGVQQSFEELVAKADQALYQAKNNGRNQVFAGKPISAAVPEYSDEEGVALA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXP0</accession>
    <name>A0A2S9GXP0_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Glutathione peroxidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_2801</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the glutathione peroxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92426">
        <property type="protein sequence ID" value="PRC92426"/>
        <property type="gene ID" value="S2091_2801"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004602">
        <property type="term" value="F:glutathione peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00340">
        <property type="entry name" value="GSH_Peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000889">
        <property type="entry name" value="Glutathione_peroxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029759">
        <property type="entry name" value="GPX_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11592">
        <property type="entry name" value="PTHR11592"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00255">
        <property type="entry name" value="GSHPx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000303">
        <property type="entry name" value="Glutathion_perox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01011">
        <property type="entry name" value="GLUTPROXDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00460">
        <property type="entry name" value="GLUTATHIONE_PEROXID_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51355">
        <property type="entry name" value="GLUTATHIONE_PEROXID_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2 5 8" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015591810" description="Glutathione peroxidase" evidence="6">
        <location>
            <begin position="25"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="7">
        <location>
            <begin position="27"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000303-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC92426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="200" mass="21952" checksum="2DB783F45963A2FD" modified="2018-07-18" version="1">MLIFNKVKFCLACAITLFSIGIFAQTPSAQTPTPAQSAPQSCPAILHYTFNRLQDDSKQDLCQYAGKVVLVVNTASFCGFTKQYEGLEALYAKYADKGLVVLGFPSNDFGKQEPGSSKEIADFCYNTYGVKFPMFAKSSVKGDEANPLYQALIKATGTTPKWNFYKYLIDRKGNIVDSYTSVTTPESETLVGPIEKALVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXR4</accession>
    <name>A0A2S9GXR4_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 4">Acylphosphatase</fullName>
            <ecNumber evidence="3 4">3.6.1.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_2873</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 4">
            <text>an acyl phosphate + H2O = a carboxylate + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:14965"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29067"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:59918"/>
            <dbReference type="EC" id="3.6.1.7"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the acylphosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.7" evidence="3 4"/>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92498">
        <property type="protein sequence ID" value="PRC92498"/>
        <property type="gene ID" value="S2091_2873"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003998">
        <property type="term" value="F:acylphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020456">
        <property type="entry name" value="Acylphosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001792">
        <property type="entry name" value="Acylphosphatase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036046">
        <property type="entry name" value="Acylphosphatase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017968">
        <property type="entry name" value="Acylphosphatase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47268">
        <property type="entry name" value="PTHR47268"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00708">
        <property type="entry name" value="Acylphosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54975">
        <property type="entry name" value="SSF54975"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00151">
        <property type="entry name" value="ACYLPHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51160">
        <property type="entry name" value="ACYLPHOSPHATASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acylphosphatase-like" evidence="7">
        <location>
            <begin position="2"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="66"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="17"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC92498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="92" mass="9913" checksum="5E6720CE6642D0C1" modified="2018-07-18" version="1">MIKRLMIEGRVQGVGYRASFADKAIALGLSGWVRNRRDGSVEACIHGDAPAIESIITWSRHGPPGAGVRNVTVEDTEEPAPSDGKFKILPTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXW1</accession>
    <name>A0A2S9GXW1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Dyp-type peroxidase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2608</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92553">
        <property type="protein sequence ID" value="PRC92553"/>
        <property type="gene ID" value="S2091_2608"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006314">
        <property type="entry name" value="Dyp_peroxidase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04261">
        <property type="entry name" value="Dyp_perox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01413">
        <property type="entry name" value="Dyp_perox_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51404">
        <property type="entry name" value="DYP_PEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2 3" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="301" mass="32860" checksum="2C6EB5F67B197675" modified="2018-07-18" version="1">MSTNLPTTQAGIMQTIPAHANFLIFNLKTDGKSQVDYVAALQKLAPLVDGDKVVLGIGLSLVTALKKQVSDLRDFPVFPDAKVALPVNKAAVWCWLRESERGALVKQSQRVVAALSGAFELVSCVDAFKFGAVQDLTGYEDGTENPQAQAAIDAAIVQQRGAGQDGASFVAVQQWLHHWNKFDAMSTDEQDNIIGRRISDNEELDDAPESAHVKRTAQESFDPEAFVLRRSMPWSLGTQSGFYFVAFGRTLDAFEAQLKRMSGAEDGIVDGLFRFSQPQTGGYFWCPPMLAGKVDLSLVLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYB9</accession>
    <name>A0A2S9GYB9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Sugar transferases involved in lipopolysaccharide synthesis</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_2443</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial sugar transferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92713">
        <property type="protein sequence ID" value="PRC92713"/>
        <property type="gene ID" value="S2091_2443"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003362">
        <property type="entry name" value="Bact_transf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02397">
        <property type="entry name" value="Bac_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="domain" description="Bac_transf" evidence="3">
        <location>
            <begin position="2"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC92713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="186" mass="21258" checksum="A67393D6BE32DC01" modified="2018-07-18" version="1">MKRIFDLFLTVIAGLILLIPIVLVSLFVKLTSTGPIVYWSDRVGRNNKIFRMPKFRTMQINTPAVATHLLSDPKQYLTPIGSFLRKSSLDELPQLWSILCGDMSFVGPRPALFNQDDLISLRTSQQVHTLLPGLTGWAQINGRDELPIPQKVTLDVYYLEHRSFFLDFKILFLTFLKVVKRDGVSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYD5</accession>
    <name>A0A2S9GYD5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Beta-lactamase superfamily domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2451</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92721">
        <property type="protein sequence ID" value="PRC92721"/>
        <property type="gene ID" value="S2091_2451"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004115">
        <property type="term" value="F:3',5'-cyclic-AMP phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006198">
        <property type="term" value="P:cAMP catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07735">
        <property type="entry name" value="class_II_PDE_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000396">
        <property type="entry name" value="Pdiesterase2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12706">
        <property type="entry name" value="Lactamase_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00388">
        <property type="entry name" value="PDIESTERASE2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lactamase_B" evidence="1">
        <location>
            <begin position="18"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="254" mass="28391" checksum="E7622CA6360F18CD" modified="2018-07-18" version="1">MKLQVLGCAGGIGGREQLTTCLWLDHDVLLDAGTGLSTLSLHQLCTIDHVFLTHSHLDHVAGLAFLLDSVLGKRHTPITVHASATVIHTLKTHLFNWQLWPDFTVIPSPTNGILRWEVMEPGSTLQINDKHIQSKPVNHTVDAVAYWVHNRMNGFLFTGDLSHSPDLWACFANEEKLRHVIVDCSFPNSAAELAHESKHYCPKSLQSDIRAMPKSIEFSVTHLKPGQENLILSELRSNSERQFNALYSGAQFTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYD9</accession>
    <name>A0A2S9GYD9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2469</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92739">
        <property type="protein sequence ID" value="PRC92739"/>
        <property type="gene ID" value="S2091_2469"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="215" mass="23210" checksum="320B77A4B1CCEF49" modified="2018-07-18" version="1">MITLIFEGIANLSSVRSSESIVSLLRIASGFRSNARAVQKQSPHWMTHSSRYACRLGSYGSFPLVRNFSSASHGVPGALRAWAPPLEGSRAVLTRRALRTRLVLDAPPPQPGNRSAIFGLLTASFGAAQRGCPSAKRAGTRGCAPRTKTAAWGPLIWLGPNFFGGSPRARSASLGRSCPAFLRQDGWHKQPTFALSLSEIFRFWCDAPLKNLGGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYF8</accession>
    <name>A0A2S9GYF8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="8">CyoB: cytochrome o ubiquinol oxidase, subunit I</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_2484</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the heme-copper respiratory oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92754">
        <property type="protein sequence ID" value="PRC92754"/>
        <property type="gene ID" value="S2091_2484"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070469">
        <property type="term" value="C:respirasome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004129">
        <property type="term" value="F:cytochrome-c oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016682">
        <property type="term" value="F:oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009060">
        <property type="term" value="P:aerobic respiration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.210.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023616">
        <property type="entry name" value="Cyt_c_oxase-like_su1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036927">
        <property type="entry name" value="Cyt_c_oxase-like_su1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000883">
        <property type="entry name" value="Cyt_C_Oxase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023615">
        <property type="entry name" value="Cyt_c_Oxase_su1_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014207">
        <property type="entry name" value="Cyt_c_ubiqinol_oxidase_su1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10422">
        <property type="entry name" value="PTHR10422"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00115">
        <property type="entry name" value="COX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01165">
        <property type="entry name" value="CYCOXIDASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81442">
        <property type="entry name" value="SSF81442"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02843">
        <property type="entry name" value="CyoB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50855">
        <property type="entry name" value="COX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00077">
        <property type="entry name" value="COX1_CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0249">Electron transport</keyword>
    <keyword evidence="5" id="KW-0349">Heme</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="2 5 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="26"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="69"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="112"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="156"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="200"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="237"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="285"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="320"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="354"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="390"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="425"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="462"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="503"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="599"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="623"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="domain" description="COX1" evidence="7">
        <location>
            <begin position="49"/>
            <end position="569"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC92754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="667" mass="75030" checksum="7B39183B51281F24" modified="2018-07-18" version="1">MLDQTNWLKLIFGRLTWDAIPFHEPILVVTFAMIALGGLAVLAAMTYFRLWTPLWRDWITSIDHKRIGIMYIVLGIVMLFRGFADALMMRLQQALAFGDAAGYLPPHHYDQIFTAHGVIMIFFVAMPLVTGLMNYVVPLQIGARDVAFPFLNNFSFWMTTFGSMLVMVSMFVGEFARTGWLAYPPLSGILASPDVGVDYYIWSLQIAGVGTLLSGVNLIATIVKMRAPGMTLMKMPVFVWTSLCTNVLIVAAFPVLTAVLAMLSLDRMVGTNFFTNDMGGNAMMYVNLIWIWGHPEVYILILPAFGVFSEVVPTFCSKKLFGYTSMVYASVVITILSYLVWLHHFFTMGSGASVNSFFGITTMIISIPTGAKIFNWLFTMYRGRIRFELPMMWTISFMITFVIGGMTGVLLAVPPADFMVHNSLFLIAHFHNVIIGGVVFGMFAGINYWFPKAFGYKLDTYWGKWSFWLWTIGFYVAFMPLYVLGLMGVTRRLSHFDDPSFQIWFQIAAVGAVMILFGILCFVVQLVVSYIRRESLRDVTGDPWGGRSLEWSTSSPPPSYNFAFTPFVHAKDAWHDMKSADYVRPLTGFTSIHMPKNTAAGFIIAGLSAVVGFGLIWQMWLVAGFGFAAMLAAIIIHTFNYKRDYYISADEVIRVEGERTQLLNSHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYK6</accession>
    <name>A0A2S9GYK6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Helix-turn-helix domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2518</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92788">
        <property type="protein sequence ID" value="PRC92788"/>
        <property type="gene ID" value="S2091_2518"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="1">
        <location>
            <begin position="196"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="300" mass="34246" checksum="C45FDE1583E77202" modified="2018-07-18" version="1">MALLQLDFKNERDRTLFLPAQPVRSSTDFAWKSLYFEHRTGGDFETEEHEMSGHYLMVKLNPFSKAERKVDGRTQIENQRRGTLVYIPDGCPHRVRYLTKLGGLHLMSLSKDILAEVAGELGVSNFSGVPSLGENEDRFVLEIAESLNREVEAGNPHGTLFAETYARVLATHIITRYRVVEVTNKKLPNLNQKQIRWLDQYIEAMLPHSISLPELAKQVGLSQYYFCRVFKDATGLPPYQYVLHKRLEFVCECLKKDTMSIQDIAFSAGFGDPIQMAKQFKQAHGVSPSQYRAALRSSMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYL0</accession>
    <name>A0A2S9GYL0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="12">NHLM bacteriocin system ABC transporter, ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">S2091_2531</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92801">
        <property type="protein sequence ID" value="PRC92801"/>
        <property type="gene ID" value="S2091_2531"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022515">
        <property type="entry name" value="NHPM_micro_ABC2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="PTHR24221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="SSF90123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03797">
        <property type="entry name" value="NHLM_micro_ABC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 8 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-1278">Translocase</keyword>
    <keyword evidence="2 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="425"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="462"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="535"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="566"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="643"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="684"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="11">
        <location>
            <begin position="426"/>
            <end position="710"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="742"/>
            <end position="974"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="776"/>
            <end position="783"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PRC92801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="977" mass="105704" checksum="E101E73CB7CBCE14" modified="2018-07-18" version="1">MSNEQTDTLETPLTAISELGSLGSAGARLVHADRSVWLVEHGSIDLFMVPLNAELEPGARIYLFTTGVGQLVAFPRLASDLGYGLLAVPMADCRYRVIERDDLTRMFEQTVQGCNQLALLDAFAHNLSLIPHEKLSSECLSVYPNDEYVAADTALTVCAGASGLWLSSVSGPMVYAIHDASEHELMHLHACLPAPMSIAIHLPTATQVHCYSLEEAREQGVSLDMLLDGLDSLFLSLIHATIENKKKNEADELLRLQTKTSIDSQAMSDALGGFASLFQKQYQESFSSSSKDRLLNACQIIGKSLNITFVAPPVGGVHRNLVQNIANASHVRTRVVALKGAWWKVDSGALLGFLESDKEPLALMPVRGGGYEAVNPVSGQRTKVDAQFSAQLVIFAHMFYTSLPHKSLILKDVIQFITRGFGREFIIIAAISLVSAALGMGIPIASGVLFDQAFPAADFGQMMQILMILFATILVTLLFEVTQAMVLLRIEGKASCDLQAAVWDRVLKLPVPFFRDYSAGDLATRINGINEIRQALSGTVISSILSSLFSALNVCLLFYYDIKLGVVAIILVLAAIGFNLLVGRVTARLTREAADKNGKISGMVLEYLNGIAKLRITGAESRAFSNWSTSFVMQRRLLMRASGWGNIGGTFSAVFPLLAMIVIFVWIAPVAGADNHQHLSTGEFIAFSSTFAIFLGATMNLVRISTDLLNIMSTYERTRPIMETVPEVDQNKAYPGELRGAIELSNVSFSYSPDLPPVLDDVSFSVKPGEFVALVGASGSGKSTLLRLMLGFETPSQGAIYYDGKNLGDINIGAVRRQLGVVLQGGQLMDGDIFSNIVGSTTLGSDAAWEAAKACGLDRDIEAMAMGMQTLVSDGGGTLSGGQRQRLMIARAIVNKPKIIYFDEATSALDNQTQATVSASMEQLRATRIVIAHRLSTIINADQIYVLEKGRIVQSGSYAVLMQQEGLFAELAKRQTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYT0</accession>
    <name>A0A2S9GYT0_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">tRNA pseudouridine synthase B</fullName>
            <ecNumber evidence="5">5.4.99.25</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">tRNA pseudouridine(55) synthase</fullName>
            <shortName evidence="5">Psi55 synthase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">tRNA pseudouridylate synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">tRNA-uridine isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">truB</name>
        <name evidence="9" type="ORF">S2091_2296</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>uridine(55) in tRNA = pseudouridine(55) in tRNA</text>
            <dbReference type="Rhea" id="RHEA:42532"/>
            <dbReference type="Rhea" id="RHEA-COMP:10101"/>
            <dbReference type="Rhea" id="RHEA-COMP:10102"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="EC" id="5.4.99.25"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.25" evidence="5"/>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92879">
        <property type="protein sequence ID" value="PRC92879"/>
        <property type="gene ID" value="S2091_2296"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106029">
        <property type="term" value="F:tRNA pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031119">
        <property type="term" value="P:tRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02573">
        <property type="entry name" value="PseudoU_synth_EcTruB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01080">
        <property type="entry name" value="TruB_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002501">
        <property type="entry name" value="PsdUridine_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036974">
        <property type="entry name" value="PUA_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014780">
        <property type="entry name" value="tRNA_psdUridine_synth_TruB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015240">
        <property type="entry name" value="tRNA_sdUridine_synth_fam1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032819">
        <property type="entry name" value="TruB_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13767">
        <property type="entry name" value="PTHR13767"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09157">
        <property type="entry name" value="TruB-C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16198">
        <property type="entry name" value="TruB_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01509">
        <property type="entry name" value="TruB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="SSF88697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00431">
        <property type="entry name" value="TruB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="TruB_N" evidence="6">
        <location>
            <begin position="36"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="domain" description="TruB_C_2" evidence="8">
        <location>
            <begin position="184"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="domain" description="TruB-C_2" evidence="7">
        <location>
            <begin position="246"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="5">
        <location>
            <position position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01509"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF09157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF16198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC92879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="315" mass="34504" checksum="7479E98AE535600C" modified="2018-07-18" version="1">MAETQRVKRIRDALNGVLLLDKPVGLSSNDALIQTKRLLNAKKAGHTGTLDPFATGLLPLCFGEATKFSHDLLFADKTYETVVHLGITTETGDTEGAVLENLSVGVTLEQIDAVLAQFRGPIEQVPPMYSALKRDGKPLYEYARAGITLEREARNVVIHELTLLSYEAPFLRLRVACSKGTYIRVLGEDIGRALGCGAHLNALRRTQVASLKLADAISLDAIQQMSPEQRINLLKPVDALLSDFEAIQLTDELAVRFLHGQRLALQKEGINLPELIPANLGRVRVYRFSDGKLLGSGLLQEYQVLAPERLISTSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZA9</accession>
    <name>A0A2S9GZA9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_2126</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93040">
        <property type="protein sequence ID" value="PRC93040"/>
        <property type="gene ID" value="S2091_2126"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000485">
        <property type="entry name" value="AsnC-type_HTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019888">
        <property type="entry name" value="Tscrpt_reg_AsnC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019887">
        <property type="entry name" value="Tscrpt_reg_AsnC/Lrp_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01037">
        <property type="entry name" value="AsnC_trans_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13404">
        <property type="entry name" value="HTH_AsnC-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00033">
        <property type="entry name" value="HTHASNC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00344">
        <property type="entry name" value="HTH_ASNC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50956">
        <property type="entry name" value="HTH_ASNC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH asnC-type" evidence="4">
        <location>
            <begin position="5"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC93040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="149" mass="16309" checksum="A8C61CDB9E425273" modified="2018-07-18" version="1">MKPNLDKIDNQILSLLMDDARMPVTVIAKKIAMARTTVIARIAALEQRGIIAGYGVRLNQTLFQSGVRAYVGMSVEPRSSAALVKLLQQWPEVETLCAVSGAIDYMMTLRCTSTENLDKLLDQIGDLEGVRQTSTSVILSNRIDRSALG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZD2</accession>
    <name>A0A2S9GZD2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative signal transduction protein containing EAL and modified HD-GYP domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2393</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92976">
        <property type="protein sequence ID" value="PRC92976"/>
        <property type="gene ID" value="S2091_2393"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014408">
        <property type="entry name" value="dGMP_Pdiesterase_EAL/HD-GYP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035919">
        <property type="entry name" value="EAL_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013976">
        <property type="entry name" value="HDOD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08668">
        <property type="entry name" value="HDOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003180">
        <property type="entry name" value="DiGMPpdiest_YuxH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141868">
        <property type="entry name" value="SSF141868"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51833">
        <property type="entry name" value="HDOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HDOD" evidence="1">
        <location>
            <begin position="202"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="408" mass="44657" checksum="5E3297EC5E1695B8" modified="2018-07-18" version="1">MEDVNFILREPLLNSKQQVIGYELSWQQKNTEPLNVEELNSLLVFVVEQFHDNDTGWLLADSLLFLETVPALFHLPALKLLPPANTVLTIRRSYLADEATLEAVKELRAQGYGICLRGADINRLDKTVLGLISHIEVRLSATDFAAQAKMYAALKQSSIRMVARQLVTWQDFDACAALGLDAFVGKLHLTPRPEQDSQPKGINAAQTVILQLMELVRKNADIASLEAVLRRDAGLSYKLLQYINSAGFGLRTPIQSLKHAVQLLGYSPLYRWLSVLLATASSSGYSPVLMETAIVRGRFAELLGIANLPKGDAENLFVAGMFSLLDRLLNVPMERVLATVQLPEMVSQALLTREGLYGPYLSLAEACELNSALAGSLAESLHIATADVNQAHLSALVWAKNVAAAAKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZI1</accession>
    <name>A0A2S9GZI1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2199</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93113">
        <property type="protein sequence ID" value="PRC93113"/>
        <property type="gene ID" value="S2091_2199"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="527" mass="61007" checksum="E4E5E1F5EFFE5F0E" modified="2018-07-18" version="1">MVFKHIAQKNSPQKNIECIFLGSPEAEAEALPTSRMPLLKVYQDHHNLIDALQNEKFIICGKKGAGKSAFAEYISLLADDEPNLFCKFIRQGEFNLEHIVQIGKESGHEIERENLYTWLILTNILKLFADNQAANENDEYQLLSQFLKKNSGYIDIRGSEIKEMVVKDGFEINIEYLKRFFSSKFKKDVEIKQTRAPFYKLIPHLKEIILKVLQSKDEKENGNSYLLFFDDLDINFNAKDQNSIESIISLLRVSKEINNQFFAKNNLDSKVVILLRDDIAKSTSTASADTAKIFSSYSASINWYQDEYHKSFPETELNIRKFLNERIKYAFSVEHLVVNEVDPWLSLVNDPFDKSFPAESAPKTSFKYILDHTFFRPRDLILFFAPLQNHKYRFPLVRNDIHQLIGIYCEEIVNELKNELHCFYYQDEILNIFNAIGSISTACKQSFSNSITYAQACTIFEENCNDIIPRAIFSDLFERSIIGNMGSNGYVFYKHREPRSDTYSFNAEQNIVLHSALKVYCSNKGFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZI9</accession>
    <name>A0A2S9GZI9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ATPase component of ABC transporters with duplicated ATPase domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_2206</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93120">
        <property type="protein sequence ID" value="PRC93120"/>
        <property type="gene ID" value="S2091_2206"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032781">
        <property type="entry name" value="ABC_tran_Xtn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12848">
        <property type="entry name" value="ABC_tran_Xtn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-1278">Translocase</keyword>
    <feature type="domain" description="ABC transporter" evidence="7">
        <location>
            <begin position="2"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="7">
        <location>
            <begin position="307"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="34"/>
            <end position="41"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="351"/>
            <end position="358"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC93120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="533" mass="59279" checksum="9F50CB10656EC3A9" modified="2018-07-18" version="1">MLSTANITIQFGAKPLFENISVKFGDGNRYGLIGANGCGKSTFMKILGGDLEQSSGTVMLDPGERLGKLGQNQFAFEEMRVLDVVMMGHVEMWAAMTERDALYANPEATDDDYMRAADLEAKFAEYDGYTAESRASELLMGAGIEIAQHQGPMSEIAPGWKLRVLLAQALFSNPDILLLDEPTNNLDINTIRWLENVLNQRNSTMIIISHDRHFLNQVCTHMADMDYGTLKVYPGNYDEYMLASSQARAQQLSNNAKAKDKVAELQDFVRRFSANKSKARQATSRAKQIDKIKIEDLKPSSRQNPYIRFEGEKKLHRLAMEVQSITKSYDRTLFKNISLAIEAGERIAIIGANGAGKTTFLRCLGGELAGLSPDTGLVKWAENANPGYMPQDPTEEFANGKILTDWMGDWTGEGDDDQAVRSILGRLLFSGDDVKKSVKVLSGGEKGRMMYGKLMLGRHNVLLLDEPTNHMDMESIESLNIALEKYAGTLIFVSHDREFVSSLATRILEIKEKEIVDFNGTYEEYLGSQGIEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZK2</accession>
    <name>A0A2S9GZK2_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ATP-grasp domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2223</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93137">
        <property type="protein sequence ID" value="PRC93137"/>
        <property type="gene ID" value="S2091_2223"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005479">
        <property type="entry name" value="CbamoylP_synth_lsu-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00866">
        <property type="entry name" value="CPSASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-grasp" evidence="2">
        <location>
            <begin position="249"/>
            <end position="450"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="468" mass="52114" checksum="42EEB6CF880BF551" modified="2018-07-18" version="1">MTAIPEPEFSAPFSSLSLADLELAVAQKPLNVDLHRLMFDRKHQQGDELGALAHLIAAKAIDAYLTDDGNNAAWQLYLVATGYFMKGDYAIAERWYQIVLTLDPNLAAAYQNLVVIHLHFGRHAEAEVCRARAYQIQRVFIDPVVNPVRQLLILCVGRTQGNIPYEVLLSAETSQRIKYIIDYADVTEDAQLPPYDLAFNAIGEPDVAAPLAERLDRFIQTCQRPILNLPTLVARTQRHLLSELMTGLENVVVAPCVRMEAEPVSAEQLQANIVNGDIHFPVLVRPAGSHGGQGLVRCDDLVATLTALQSTDSAHYLSSFIDCRSADGYFRKYRIIYVDKQPFAYHLAISNEWMVHYHSADMVSNAWKIAEEKLFLQNTAAVLGEPAMAALVQIGQRLNLDYAGIDFALLPDGQVFIFEANATMLVHRVASDGLLAHKNPYIQRIADAFEQMQVRRISNLDSSNTSKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZM9</accession>
    <name>A0A2S9GZM9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">HlyIII: channel protein, hemolysin III family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_1930</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPF0073 (Hly-III) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93192">
        <property type="protein sequence ID" value="PRC93192"/>
        <property type="gene ID" value="S2091_1930"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019835">
        <property type="term" value="P:cytolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004254">
        <property type="entry name" value="AdipoR/HlyIII-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005744">
        <property type="entry name" value="Hy-lIII"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20855">
        <property type="entry name" value="PTHR20855"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03006">
        <property type="entry name" value="HlyIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01065">
        <property type="entry name" value="hlyIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="36"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="76"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="102"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="129"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="154"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="185"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC93192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="205" mass="22840" checksum="5337828CB80C6B45" modified="2018-07-18" version="1">MYKGEKFNSISHLVGAGLVVIGASVLITIAGFTGDFWKIVSSSVYSLTLLMLYLFSTLYHSIRGKAKDVLQKFDHCMIYLLIAGSYTPFTLVTLHGTTGWKLFGIVWGLALIGIVQELWLANQARISSLVIYILMGWSVVLFITPLIAALGWHGFYWLAAGGIIYSVGIIFYVIDERMRHAHGIWHLFVLGGSICHFVTVLFYVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZQ0</accession>
    <name>A0A2S9GZQ0_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_2266</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93180">
        <property type="protein sequence ID" value="PRC93180"/>
        <property type="gene ID" value="S2091_2266"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="8">
        <location>
            <begin position="182"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="7">
        <location>
            <begin position="281"/>
            <end position="512"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC93180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="513" mass="56448" checksum="6843F86ECCBDCEB7" modified="2018-07-18" version="1">MHSVRAHLTNIFLVAISITLIIFGGYGYYKLSRELNANFTQQKQNTLTRLTISLPLPMWDFNTELTTNLVESEMLSPEVSAIQVFDLKSNLFASASRDKKGRIVSVVDLDKVEGIPIEADLYHQLADHSAEPALPQNKIGSVVIYFTRHRIDELLRSNALHSIFEILVIDALLIFTLRFSLRLVFTPLGQLRDALMELAEHGGEDVEELPETQKNEIGEVIQCFNQTQRKFKHVIEHLRQAEEATRAEAVKADLAYVALKAAQETMLQTEKLASLGGMVAGVAHEINTPVGITLTSASVLKEATDHLNKAMADGAMKKSEIVAYTTTAGECARLIMKNAERASHLINSFKQVASDQTSEQRREYELSAYIDEVMSSLRPTLRLNQVQVNVNCPTPIAIDGFPGAMAQVLTNLTMNAITHAFTERGQGVINITANQVGETVNLTFADNGVGIPQANIGKIFDLFFTTQRATGGTGLGLNIVHNILYKQFGGSISVSSEAGKGSCFFMHFPRVIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZS0</accession>
    <name>A0A2S9GZS0_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 3">Diaminopimelate decarboxylase</fullName>
            <shortName evidence="2">DAP decarboxylase</shortName>
            <shortName evidence="2">DAPDC</shortName>
            <ecNumber evidence="2 3">4.1.1.20</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">lysA</name>
        <name evidence="6" type="ORF">S2091_1936</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 3">
            <text>H(+) + meso-2,6-diaminoheptanedioate = CO2 + L-lysine</text>
            <dbReference type="Rhea" id="RHEA:15101"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:32551"/>
            <dbReference type="ChEBI" id="CHEBI:57791"/>
            <dbReference type="EC" id="4.1.1.20"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 2 3">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 3">Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; L-lysine from DL-2,6-diaminopimelate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.20" evidence="2 3"/>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93198">
        <property type="protein sequence ID" value="PRC93198"/>
        <property type="gene ID" value="S2091_1936"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00034">
        <property type="reaction ID" value="UER00027"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008836">
        <property type="term" value="F:diaminopimelate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06828">
        <property type="entry name" value="PLPDE_III_DapDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.37.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02120">
        <property type="entry name" value="LysA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009006">
        <property type="entry name" value="Ala_racemase/Decarboxylase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002986">
        <property type="entry name" value="DAP_deCOOHase_LysA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022643">
        <property type="entry name" value="De-COase2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022657">
        <property type="entry name" value="De-COase2_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022644">
        <property type="entry name" value="De-COase2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022653">
        <property type="entry name" value="De-COase2_pyr-phos_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000183">
        <property type="entry name" value="Orn/DAP/Arg_de-COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029066">
        <property type="entry name" value="PLP-binding_barrel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02784">
        <property type="entry name" value="Orn_Arg_deC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00278">
        <property type="entry name" value="Orn_DAP_Arg_deC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01181">
        <property type="entry name" value="DAPDCRBXLASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01179">
        <property type="entry name" value="ODADCRBXLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50621">
        <property type="entry name" value="SSF50621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51419">
        <property type="entry name" value="SSF51419"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01048">
        <property type="entry name" value="lysA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00878">
        <property type="entry name" value="ODR_DC_2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00879">
        <property type="entry name" value="ODR_DC_2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2 3" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="2 3" id="KW-0456">Lyase</keyword>
    <keyword evidence="2 3" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="2" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Orn_Arg_deC_N" evidence="5">
        <location>
            <begin position="26"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="domain" description="Orn_DAP_Arg_deC" evidence="4">
        <location>
            <begin position="270"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="region of interest" description="Pyridoxal phosphate binding" evidence="2">
        <location>
            <begin position="262"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="221"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="265"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="301"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="305"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="336"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="371"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="2">
        <location>
            <position position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC93198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="413" mass="45406" checksum="2816A8F19133918C" modified="2018-07-18" version="1">MISQQQIAQIATQVHTPCWIYDADSIRRQISRLRQFDVIRFAQKACSNTHLLRLMREQGVMVDSVSLGEIERALVAGFNPGDAGHSPIVFTADLLDTATIARVVELNIPVNCGSPQMLQQLGAAHPGHPVWLRINPGFGHGHSRKTNTGGEQSKHGIWHEHLTECLQIIQQTGLKLIGLHMHIGSGVDYAHLQSVCEAMTQQVRYVRKFGLDIDAISVGGGLSIPYRVGEEDVDTEHYFQIWDAARQQIEKMLGHSVHMEIEPGRFLVAQSGLLVSELRAQKQVGSNFFALVDAGFNDLARPAMYGSFHRISAHAPDGTPRAGALRPTVVAGPLCESGDVFTQEEGGEVVSQDLPVCEIGDLLVFHDAGAYGASMSSNYNSRPLIPEILVDGEHIKKIRRRQTVQELIALELD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZU5</accession>
    <name>A0A2S9GZU5_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF6434 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1997</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93259">
        <property type="protein sequence ID" value="PRC93259"/>
        <property type="gene ID" value="S2091_1997"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045492">
        <property type="entry name" value="DUF6434"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20026">
        <property type="entry name" value="DUF6434"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6434" evidence="1">
        <location>
            <begin position="3"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="69" mass="8448" checksum="F9B4DD0BFC7059DF" modified="2018-07-18" version="1">MDFDWHSNPITRTTIVDTNYKNTQNVRRFLVTQCGTDFKFDKDFMAWIRNDMVKNMGDVADEWLRRRRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZU7</accession>
    <name>A0A2S9GZU7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Efflux transporter, RND family, MFP subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_1989</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93251">
        <property type="protein sequence ID" value="PRC93251"/>
        <property type="gene ID" value="S2091_1989"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006143">
        <property type="entry name" value="RND_pump_MFP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01730">
        <property type="entry name" value="RND_mfp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="17"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="domain" description="HlyD_D23" evidence="3">
        <location>
            <begin position="83"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC93251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="397" mass="43550" checksum="D7B6D2EDE4D00608" modified="2018-07-18" version="1">MSDNPLPSLRRSPTRRLYLIGAIFLVVALLIALIGITSRSKHEHKLEEGVKSKHITVQVITPEYGPSIQPLILPGNVRANIEAPIYARVAGYLKIWHTDIGAHVKKGQLLGEIDTPELDQQIVRERANLLVAQSNLDLANITSKRWQNLVVSNSVSRQESDEKSADAKAKNDFLNSVRAQLNNLLAQQSFNHITAPFDGVITERNTDIGKLINPGSNNGQSLFQIADSRQLRIYVDVPQNYSADIKKGMTAELHFPEHPSQVFPATLVSTSQAIHESSRTLTAQLQMQNTDEEILPGTYAEVHFSLPSKGNVFRLPASTLLFRKEGLQVATVTTDNHVDLKFITLGRDLGSAVEVTSGISSKDRVIDSPSDSIAQGSVVRIKSAENVPVIVDSSEPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZW4</accession>
    <name>A0A2S9GZW4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2012</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93274">
        <property type="protein sequence ID" value="PRC93274"/>
        <property type="gene ID" value="S2091_2012"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010696">
        <property type="entry name" value="DUF1272"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06906">
        <property type="entry name" value="DUF1272"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="81" mass="8610" checksum="EBF0DBDC20A34223" modified="2018-07-18" version="1">MLLLRPNCECCNGDLPPDATEAKICSFECTFCASCANSKLNNICPNCGGELVARPRRPANKLATYPASAERIYKPAGCAGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZW8</accession>
    <name>A0A2S9GZW8_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">UPF0102 protein S2091_1981</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1981</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the UPF0102 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93243">
        <property type="protein sequence ID" value="PRC93243"/>
        <property type="gene ID" value="S2091_1981"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00048">
        <property type="entry name" value="UPF0102"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011856">
        <property type="entry name" value="tRNA_endonuc-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003509">
        <property type="entry name" value="UPF0102"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34039">
        <property type="entry name" value="PTHR34039"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02021">
        <property type="entry name" value="UPF0102"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00252">
        <property type="entry name" value="TIGR00252"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="121" mass="13834" checksum="EEFF5250A765FE8B" modified="2018-07-18" version="1">MQWLTKLTKNRQLLGQEGEKQALRYLHEQGLVHIESNFRRPFGEIDLIMQDHSTLVFVEVRSRAQSQFGGAAASVTRAKQRRLVLAAQAYLQRYPQPPPCRFDVIAIDAGVVEWLKNVMDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H039</accession>
    <name>A0A2S9H039_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">PKHD-type hydroxylase S2091_1974</fullName>
            <ecNumber evidence="7">1.14.11.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_1974</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="7">Binds 1 Fe(2+) ion per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>L-ascorbate</name>
            <dbReference type="ChEBI" id="CHEBI:38290"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.11.-" evidence="7"/>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93236">
        <property type="protein sequence ID" value="PRC93236"/>
        <property type="gene ID" value="S2091_1974"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016706">
        <property type="term" value="F:2-oxoglutarate-dependent dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031418">
        <property type="term" value="F:L-ascorbic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00657">
        <property type="entry name" value="Hydroxyl_YbiX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041097">
        <property type="entry name" value="PKHD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023550">
        <property type="entry name" value="PKHD_hydroxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006620">
        <property type="entry name" value="Pro_4_hyd_alph"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044862">
        <property type="entry name" value="Pro_4_hyd_alph_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41536">
        <property type="entry name" value="PTHR41536"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13640">
        <property type="entry name" value="2OG-FeII_Oxy_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18331">
        <property type="entry name" value="PKHD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00702">
        <property type="entry name" value="P4Hc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="6 7" id="KW-0408">Iron</keyword>
    <keyword evidence="2 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0847">Vitamin C</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="8">
        <location>
            <begin position="80"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="98"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="100"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="161"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="171"/>
        </location>
        <ligand>
            <name>2-oxoglutarate</name>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC93236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="228" mass="25000" checksum="9F8E5E1612615DDB" modified="2018-07-18" version="1">MLLKIPHLLSPDQVRFIREKLDQAGEAWVDGRVTAGHQGAPVKRNLQIAENTPVARELGDLILAALERNPLFISGALPNQVYPPMFNRYEGGMQFGSHVDGAIRLIPGTGIKIRTDVSATLFLSDPDEYEGGELMIEDTYGVHSAKLAAGDMLIYPASSLHRVSPVTSGARIASFFWIQSLIKDDGQRSMLFDLDTAIQRLNASGADEIARTNLTGCYHNLLRMWGAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H065</accession>
    <name>A0A2S9H065_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Isocitrate dehydrogenase kinase/phosphatase</fullName>
            <shortName evidence="4">IDH kinase/phosphatase</shortName>
            <shortName evidence="4">IDHK/P</shortName>
            <ecNumber evidence="4">2.7.11.5</ecNumber>
            <ecNumber evidence="4">3.1.3.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">aceK</name>
        <name evidence="5" type="ORF">S2091_2081</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>ATP + L-seryl-[isocitrate dehydrogenase] = ADP + H(+) + O-phospho-L-seryl-[isocitrate dehydrogenase]</text>
            <dbReference type="Rhea" id="RHEA:43540"/>
            <dbReference type="Rhea" id="RHEA-COMP:10605"/>
            <dbReference type="Rhea" id="RHEA-COMP:10606"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.5"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the AceK family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.5" evidence="4"/>
    <dbReference type="EC" id="3.1.3.-" evidence="4"/>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93343">
        <property type="protein sequence ID" value="PRC93343"/>
        <property type="gene ID" value="S2091_2081"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008772">
        <property type="term" value="F:[isocitrate dehydrogenase (NADP+)] kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004721">
        <property type="term" value="F:phosphoprotein phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006006">
        <property type="term" value="P:glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006097">
        <property type="term" value="P:glyoxylate cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00747">
        <property type="entry name" value="AceK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010452">
        <property type="entry name" value="Isocitrate_DH_AceK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39559">
        <property type="entry name" value="PTHR39559"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06315">
        <property type="entry name" value="AceK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000719">
        <property type="entry name" value="AceK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 4" id="KW-0329">Glyoxylate bypass</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3 4" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="active site" evidence="4">
        <location>
            <position position="382"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="326"/>
            <end position="332"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="347"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC93343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="605" mass="70719" checksum="E9FB741231711FD8" modified="2018-07-18" version="1">MPQVAFPKLLSSQIAFDIARTILDGFNKHYRLFRAVSQQAKTRFELAEWKEGQKIARERISYYDKRVIECATILEDDYDEADLTDPVWREVKLHYMGLLIDHMQPELAETFFNSVCTKMLHRNYYNNDFIFMRPAVATDYIESDHLPTYRVYYPANDGFHYSLKRIITNFRLETPFADLDRDVTAIAQRLNELIGAERVEPNQQLQVLSNLFFRNKGAYIVGKVVNGNREYPFIVPILHNRHNHLILDTVLLDPVQITVLFSFTRAYFMVDMEVPSAYVQFLRSIMPRKPRSEIYTVLGLQKHGKNLFYRDFLHHLRYSSDQIQEAPGIRGLVMLVFALPSFPYVFKVIKDSFPPPKDTTKELIKEKYLLVKNHDRVGRMADTLEYSDVTFPRSRITESLLAEIRRYAPSVLEENENEVVIKHLYIERRMVPLNIWLMEAEKEHNNAAIEHGIREYGNAIKELVAANIFPGDMLYKNFGVTRLGRVVFYDYDEIEYTVDCNFRSIPLARNDEDEMAAEPWYHIAKNDVFPEQFAPFLLGNAKVREYFMKYHADLLTPGYWQACKKRIMEGHVEDVFPYPQEIRFCHSSASRGSGINTGPDFNPAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H084</accession>
    <name>A0A2S9H084_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Response regulator containing a CheY-like receiver domain and an HD-GYP domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_2098</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93360">
        <property type="protein sequence ID" value="PRC93360"/>
        <property type="gene ID" value="S2091_2098"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008081">
        <property type="term" value="F:phosphoric diester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037522">
        <property type="entry name" value="HD_GYP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013976">
        <property type="entry name" value="HDOD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08668">
        <property type="entry name" value="HDOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51831">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51832">
        <property type="entry name" value="HD_GYP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="12"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="domain" description="HD-GYP" evidence="4">
        <location>
            <begin position="175"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="domain" description="HD" evidence="3">
        <location>
            <begin position="197"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC93360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="432" mass="48649" checksum="89707D105C336A90" modified="2018-07-18" version="1">MSLETTDSKSAKILCVDDEPNILSSLRRLFRAKGYQVFIAEGGREGLKIMESEQIDLVISDMRMPEMDGAQFLEEVRSKWPDCIRILLTGFSEVHSIIAAINRGEIHRYIAKPWDENDILLIVKQALERKYLFDEKLRLEALTSSQNEELKNLNASLEFKVQERTEALKTANEKLKESFLTSIKVFSSLIDMRGGKLAGHSRRVADIARKIAVRMKLDFNEVQDIFVAGLLVDIGKIGFSDDLLSMPMNKMNGEELGLYHKHTIRAEQVLMPLEDLQATAKILRSQHERVDGKGFPDGLMEDEIPIGARVLAIASDYDNLQTGSLVQRRVPAEEAQAIIIRSAGSRYSERVVAAFKEVFNHQNGDVQDHHEVTPKNLLVGMVLFTDLISRDGTLLIPADCVLNEHIIEKIILHSVSSGVHMTLKIRNSGRHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0B2</accession>
    <name>A0A2S9H0B2_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="13 14 15">UvrABC system protein B</fullName>
            <shortName evidence="14">Protein UvrB</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Excinuclease ABC subunit B</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">uvrB</name>
        <name evidence="20" type="ORF">S2091_1780</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11 14">The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12 14 15">Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 14 15">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="14">The beta-hairpin motif is involved in DNA binding.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 14 15">Belongs to the UvrB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93393">
        <property type="protein sequence ID" value="PRC93393"/>
        <property type="gene ID" value="S2091_1780"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009380">
        <property type="term" value="C:excinuclease repair complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009381">
        <property type="term" value="F:excinuclease ABC activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009432">
        <property type="term" value="P:SOS response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00204">
        <property type="entry name" value="UvrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006935">
        <property type="entry name" value="Helicase/UvrB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001943">
        <property type="entry name" value="UVR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036876">
        <property type="entry name" value="UVR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004807">
        <property type="entry name" value="UvrB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041471">
        <property type="entry name" value="UvrB_inter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024759">
        <property type="entry name" value="UvrB_YAD/RRR_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24029">
        <property type="entry name" value="PTHR24029"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04851">
        <property type="entry name" value="ResIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02151">
        <property type="entry name" value="UVR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12344">
        <property type="entry name" value="UvrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17757">
        <property type="entry name" value="UvrB_inter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46600">
        <property type="entry name" value="SSF46600"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00631">
        <property type="entry name" value="uvrb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50151">
        <property type="entry name" value="UVR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 14" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 14 15" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6 14 15" id="KW-0228">DNA excision</keyword>
    <keyword evidence="9 14 15" id="KW-0234">DNA repair</keyword>
    <keyword evidence="8 14 15" id="KW-0267">Excision nuclease</keyword>
    <keyword evidence="4 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 14 15" id="KW-0742">SOS response</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="18">
        <location>
            <begin position="51"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="19">
        <location>
            <begin position="455"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="domain" description="UVR" evidence="17">
        <location>
            <begin position="652"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Beta-hairpin" evidence="14">
        <location>
            <begin position="117"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <begin position="64"/>
            <end position="71"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00025647"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00026033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00029504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU003587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="PRC93393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="699" mass="79415" checksum="206E824452754608" modified="2018-07-18" version="1">MADLAGISITDPQKNAVPEGQTVRFPNSPYQLFQPFAPAGDQPVAIDQLVEGINDGLAYQTLLGVTGSGKTYTMANVIARTGRPAIVFAPNKTLAAQLYSEFREFFPHNAVEYFVSYYDYYQPEAYVPQRDLFIEKDSAINEHIEQMRLSCTKSLMERRDVIIVATVSAIYGIGNPNEYHQMILTLRAKDRVSQRDIIARLIQMQYTRNEVDFGRGTFRVRGDTIDIFPAEHAELAVRVEMFDDEIENLQLFDPLTGRIKQKIVRFTVYPGSHYVTPRATVLRAIETIKAELGERLVFFRKENKLIEEQRIEQRTRFDLEMMSEIGFTKGIENYSRHLSGALPGEPPPTLVDYLPKDALMFLDESHVLIGQFTGMYNGDRARKTNLVDYGFRLPSALDNRPLRFDEFESKMRQTVFVSATPAAYEAEHTNQVVEQVVRPTGLVDPMIIVLPASTQVDDLMTQIHMRVKKNERILVTTLTKRMAEQLTDFLGEHGIKVRYLHSDIDTVERVEILRDLRLGTFDVLVGINLLREGLDIPEVSLVAILDADKEGFLRSERSLIQTIGRAARNLNGMAILYGDKITNSMSRAMEETERRRNKQIAFNKANNITPTGVVKHIRDLIDGVYNPQAARAELDAAQEHARYEVMSEKQVSKEIKRLEKSMLDHAKNLEFEKAAQVRDQLAQLKLQLFGSSGATDLVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0E0</accession>
    <name>A0A2S9H0E0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phage baseplate assembly protein W</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1836</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93449">
        <property type="protein sequence ID" value="PRC93449"/>
        <property type="gene ID" value="S2091_1836"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007048">
        <property type="entry name" value="IraD/Gp25-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04965">
        <property type="entry name" value="GPW_gp25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GPW_gp25" evidence="1">
        <location>
            <begin position="3"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="112" mass="12854" checksum="C1A3549CEB73AC17" modified="2018-07-18" version="1">MVSAEKDIKQSLLIILSTNLGERVMQPSFGCGLKSQIYENINESTLTVLKDLIQRAILFYEPRVKLESIYTDISAAYEGRLDFTIVYDIITSNTRHNIVYPFYLREGTDVQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0I4</accession>
    <name>A0A2S9H0I4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1876</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AHA1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93489">
        <property type="protein sequence ID" value="PRC93489"/>
        <property type="gene ID" value="S2091_1876"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013538">
        <property type="entry name" value="Activator_of_Hsp90_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08327">
        <property type="entry name" value="AHSA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="158" mass="17996" checksum="91EBDC450FD671EC" modified="2018-07-18" version="1">MKKPDFVYVTYIATTLEKVWQALVDTDVTRKYWMDPVAGCVRVNVSDWQPGSRWEHQRLDDARTTDIVGKVVESNPPRRLVITWARPNEAEDESKHSRVAFDIEPYGDGLIRLMVTHDDLERDPQMLEGISGGWPKVLSNLKTLLETGHALQHSPSAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0N4</accession>
    <name>A0A2S9H0N4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">GGDEF: diguanylate cyclase (GGDEF) domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93513">
        <property type="protein sequence ID" value="PRC93513"/>
        <property type="gene ID" value="S2091_1900"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="442"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="2">
        <location>
            <begin position="518"/>
            <end position="659"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="698" mass="77748" checksum="F27E140EBF418D81" modified="2018-07-18" version="1">MLIIAIHIRNLLPHWMLTIVFCCSAMLSVLAYAKPTPTQTEITRLQKLGESQPEQAIKQLQTLQQQLPIDAIQTDRRNLLLVQIPLYIDTGNKEQAKALIAGLMKIGNQFDDPVANIMAMNFQAKILQDEGKYGEGLAVIEQTFVSVKLSDDNLLINQVESRAGELYSLIGNFQTALQHQLSALNALDSIKENSWQSDLLRAKTLNSVGRLYLSLKDDDMALSYLAKARVLAQRLDAPALVASIANNNGYAYADLEQWTSAIAAYQESLFIARKVDNRAAEAKSLGNLADASLNQGNYSACVQYSQQSMDIAHKDGITITEGIAHLNLGVCRMYMGQVAKGVAEAKLGVDFVRKTNAKPVLEGMLSDLSKAYEKVGLYQDSLKILREKDQITSGLFQAARDRTIIEMKVHYDLTQRQKEIEKLEQKNTLQHVEIENKNLQRIISILTIIGIAATAIGLFLLYRKVRRSNQRLRAANLKLKYQSTRDPLTGLLNRRAFQNVMESFDQKTERRVADMNGLHDVLVLLDIDHFKYVNDTYGHPIGDVVLIELSKRLQNILREKDMLMRWGGEEFLIYLYRVPAEKVSQIIQRELAVVGGTPVKQNDVDDAIVPVTISAGYILMPLPGIGETALSWEKAMQLVDVALYMAKTNGRNQAIGVTSVKGSKEQINALIEGDLQGAVENGTVVLQRIAGPATEQKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0R9</accession>
    <name>A0A2S9H0R9_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">N-acetylmuramoyl-L-alanine amidase</fullName>
            <ecNumber evidence="2">3.5.1.28</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_1586</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolyzes the link between N-acetylmuramoyl residues and L-amino acid residues in certain cell-wall glycopeptides.</text>
            <dbReference type="EC" id="3.5.1.28"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.28" evidence="2"/>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93585">
        <property type="protein sequence ID" value="PRC93585"/>
        <property type="gene ID" value="S2091_1586"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008745">
        <property type="term" value="F:N-acetylmuramoyl-L-alanine amidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009253">
        <property type="term" value="P:peptidoglycan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02696">
        <property type="entry name" value="MurNAc-LAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021731">
        <property type="entry name" value="AMIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002508">
        <property type="entry name" value="MurNAc-LAA_cat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01520">
        <property type="entry name" value="Amidase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11741">
        <property type="entry name" value="AMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00646">
        <property type="entry name" value="Ami_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="domain" description="MurNAc-LAA" evidence="5">
        <location>
            <begin position="302"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="185"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="185"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC93585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="472" mass="52147" checksum="B809BF4F16013C8A" modified="2018-07-18" version="1">MSEPTQFRSESVTQMDKKLNKQKRSRRIFLQSGATLLLSVLVPKLSYAAQILAVRVWPAEEYTRVTLEGDVELNATQFIVKDPLRMVVDIEGLELNSTLKEIIAKIQSNDPYIKQVRVGQNRPNVVRLVFDLKEEINPQVFTLKPVGEYKYRLVFDLYPVNPVDPIAALIEKGQWLQDAPVATLGDESQQTMQPQPQLQAPQLQAPQAQAMPQPKLNPNPEQPLQTAPDLKNVPQLTRMITIALDPGHGGEDPGAIGRGGSREKDVVLSIAKRLKAKIETQPNMRVFLTRDADFFVPLNVRVEKARKVQADLFMSIHADAFIESSARGSSVFALSDKGASSTAARWLANKENSADLIGGVNIKNHDKQLASVLLDLSTTAQISDSLKLGSAILNEIGGINRLHKGSVEQAGFAVLKAPDIPSVLIETAFISNPEEEAKLTDENYQNQMADAILKGINRYFAKKPPLAKNRLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0S9</accession>
    <name>A0A2S9H0S9_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_1596</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93595">
        <property type="protein sequence ID" value="PRC93595"/>
        <property type="gene ID" value="S2091_1596"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01590">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Histidine kinase" evidence="5">
        <location>
            <begin position="216"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="163"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC93595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="453" mass="49486" checksum="BA3E1AC8FC631666" modified="2018-07-18" version="1">MPMHAIADEIPDKFIAKWQNTTNVMADIFDVPAGLIMRVLPEQIEVLVSSHTAKNPYEAKEKANLHTGLYCETVMASRTILQVPNALLDEHWNHNPDVALNMISYLGVPLMLPNEEVFGTICVLDNKTRSYQTKYIDLLWEIKKSIEADFKIIEQQAKLQASYAEVLQAIESQKRDAVKLEQANTELSIALASLTKMQCELVRAETMAALGSLVAGVSHELNTPLGNSMMAASSLQYQVATLAAELPKGITRGRINEFVATLGEAADILMRSLSRTADMVSSFKQVAVDQTSLNHRSFSLKATIADILMTLTSPISESQVVVESDIPAMITMDSYPGPLCQILSILISNSIMHAFVGRTHGKITVSAELQEDDMVRLIICDDGIGIPKANLARVFDPFFTTAMGHGGSGLGLHIAYNLAHSALRGTIVVESLPDQGARFTLTLPRVAPVTELK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0Y8</accession>
    <name>A0A2S9H0Y8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_1656</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93655">
        <property type="protein sequence ID" value="PRC93655"/>
        <property type="gene ID" value="S2091_1656"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015562">
        <property type="term" value="F:efflux transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003423">
        <property type="entry name" value="OMP_efflux"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010131">
        <property type="entry name" value="RND_efflux_OM_lipoprot_NodT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02321">
        <property type="entry name" value="OEP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01845">
        <property type="entry name" value="outer_NodT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0564">Palmitate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1134">Transmembrane beta strand</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015371696" evidence="2">
        <location>
            <begin position="23"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="103"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU362097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC93655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="483" mass="51681" checksum="71C095069FC2BEF4" modified="2018-07-18" version="1">MRVKRWTAMAAGVAILGGCSLAPVYQTPAVSIATDSWKDQPWQSAQPADDLPHGQWWQIYGDPTLDALEAKIDQDNPTLAAALARYDQATAYIRQSQAAQLPTLDSGASLTHNRQSDHRPLRGSNQPDVYSANTIGVGLNYELDVWGRVRNLVESAKAGAQASAADLESVRLSLHAQLADNYVRLRGVDAQAKLLNDTVSAYTRALSLTQNRHAGGVASGLDVARAETQLSSVRAQAADIASQRALFEHAIASLTGQPAMNFSLPMLSGTMAIPHTPVGMPSTLLQRRPDIAAAERRTAAANANIGVARAAYYPSISLGALFGVQNTGQAGLLSAPNNYWTLGPSVVFNLFDGGLRDAKVTEARAALDQTGAEYRATVLAAFQQVEDDLSRLKYDHEGELDQNAAVQSAEKTLTLAFNRYREGAVNYLEVVTAQAAALAAERSALDLHTQQLRTSVDLIRALGGGWSQEPDQNQATAKTAMQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0Z4</accession>
    <name>A0A2S9H0Z4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Biopolymer transport protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_1624</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the ExbD/TolR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93623">
        <property type="protein sequence ID" value="PRC93623"/>
        <property type="gene ID" value="S2091_1624"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003400">
        <property type="entry name" value="ExbD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30558">
        <property type="entry name" value="PTHR30558"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02472">
        <property type="entry name" value="ExbD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC93623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="139" mass="15340" checksum="6B97225AD86A83A8" modified="2018-07-18" version="1">MSMGSLSDSDEDDFNPEINTTPLVDVMLVLLIIFIITIPVLNHNIKIDLPHASSKVDKVKPENIQLAIDADGQLFWDKELLDQSELQARIASAALKEPQPELHLRAERLTPYEKIAQVMSAAQSGGLTKIGFVTEPGKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H166</accession>
    <name>A0A2S9H166_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Putative glucose-6-phosphate 1-epimerase</fullName>
            <ecNumber evidence="3">5.1.3.15</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_1691</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>alpha-D-glucose 6-phosphate = beta-D-glucose 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:16249"/>
            <dbReference type="ChEBI" id="CHEBI:58225"/>
            <dbReference type="ChEBI" id="CHEBI:58247"/>
            <dbReference type="EC" id="5.1.3.15"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the glucose-6-phosphate 1-epimerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.1.3.15" evidence="3"/>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93690">
        <property type="protein sequence ID" value="PRC93690"/>
        <property type="gene ID" value="S2091_1691"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047938">
        <property type="term" value="F:glucose-6-phosphate 1-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09020">
        <property type="entry name" value="D-hex-6-P-epi_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008183">
        <property type="entry name" value="Aldose_1/G6P_1-epimerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025532">
        <property type="entry name" value="G6P_1-epimerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014718">
        <property type="entry name" value="GH-type_carb-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01263">
        <property type="entry name" value="Aldose_epim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016020">
        <property type="entry name" value="PHexose_mutarotase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="SSF74650"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" evidence="4">
        <location>
            <position position="139"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR016020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR016020-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC93690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="272" mass="30081" checksum="7A68257CC20C00A2" modified="2018-07-18" version="1">MITTLRTADGAQVQIAHNGAQVISWIPANQPEQLFLSKTSSSDAGAALRGGVPVIFPQFASLGLLPKHGFARTQLWHKRASDHPDRAVFELRDNEITRAIWPHAFWAELTVTLSGAELEIELAIHNTGNTEFSFTCALHTYLRVEHIEQVRVIGLQGTHYRDSVIGVENCVEMDEVLTIHGQVDRIYMNAPTRLDVQQARQRLAVFSNGFADAVVWNPGAELGRTLADLEPNGYERMLCVEAAAIAEPICLPIDATWRASQRLVVQPSARSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1A2</accession>
    <name>A0A2S9H1A2_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Glycine--tRNA ligase alpha subunit</fullName>
            <ecNumber evidence="9">6.1.1.14</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Glycyl-tRNA synthetase alpha subunit</fullName>
            <shortName evidence="9">GlyRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">glyQ</name>
        <name evidence="10" type="ORF">S2091_1373</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-tRNA(Gly)</text>
            <dbReference type="Rhea" id="RHEA:16013"/>
            <dbReference type="Rhea" id="RHEA-COMP:9664"/>
            <dbReference type="Rhea" id="RHEA-COMP:9683"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78522"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.14"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="3 9">Tetramer of two alpha and two beta subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.14" evidence="9"/>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93764">
        <property type="protein sequence ID" value="PRC93764"/>
        <property type="gene ID" value="S2091_1373"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004820">
        <property type="term" value="F:glycine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006426">
        <property type="term" value="P:glycyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00733">
        <property type="entry name" value="GlyRS_alpha_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00254">
        <property type="entry name" value="Gly_tRNA_synth_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006194">
        <property type="entry name" value="Gly-tRNA-synth_heterodimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002310">
        <property type="entry name" value="Gly-tRNA_ligase_asu"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02091">
        <property type="entry name" value="tRNA-synt_2e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01044">
        <property type="entry name" value="TRNASYNTHGA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00388">
        <property type="entry name" value="glyQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50861">
        <property type="entry name" value="AA_TRNA_LIGASE_II_GLYAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 9 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC93764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="305" mass="34762" checksum="E4947C07498AE524" modified="2018-07-18" version="1">MLTFQQIILTLQDYWNKQGCALLQPLDLEVGAGTSHPATFLRAIGPEPWRAAYVQPSRRPKDGRYGENPNRLQHYYQYQVVLKPAPENILDLYLGSLAAVGLDLQQNDVRFVEDDWENPTLGAWGLGWEVWLNGMEVTQFTYFQQVGGLDCKPVLGEITYGIERLAMYLQGVENVYDLVWTEWEENGVTKRLTYGDVYHQNEVEQSTFNFEHSNTEFLFSLFTNYETEAKRMLEVPLALPAYELVLKAAHTFNLLDARGAISVTERAAYMGRIRNLSRTVATAYYNSREALGFPMLSQSSSQSAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1B0</accession>
    <name>A0A2S9H1B0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Tetratricopeptide repeat</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1380</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93771">
        <property type="protein sequence ID" value="PRC93771"/>
        <property type="gene ID" value="S2091_1380"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015417311" evidence="1">
        <location>
            <begin position="22"/>
            <end position="596"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="596" mass="66402" checksum="5AA5F2FA6E934C5A" modified="2018-07-18" version="1">MKISYYIVPLALISGILSGCASMTPAINEASNITLVPDPAPIIPEESTSVASKENLPNVELTDEILFKVVSAEIAFQRADFPAAFATMMAVAQQTRDPRLPKRAMEMALIAKQPLQAFIASRLWHEYSPDSDEATQYYLGFMVINNNLAEVNTIISQRLAGATPKERGLIILQTQRLVMRGTDKEASFKLLEELCKPYPDLLETHLALAQAAYASNNSVRALVEAHAAIMLSPNSQIAALTLAQVSASPDAALKALADFLIQNPTAHEVRRAYAGMLIEQKQFAQARSQFDILQAERPQDPAIMYTQGVLALQMNDVVSAEKNLKDFVNELEASSSEQRDPTSAYLYLSQIADDRNDGVAALDWLSKVQSYNGKNAAYFNAQLRTALLMAKYGQLDQARQFLHELKASPEEQIEIIQLDAELLRNAKRDADAMSLLQEATKSHPDNPDLLYDFAMMAEKFDRIDEMEKALRQVIKINPENQHAYNALGYSFADRNIRLPEARALIEKALSLAPDDAFIIDSMGWLEFRENQNEKALAFLQRAYQIRPDVEIAVHVGEVLWSMGDQQKAKSIWKEAQQKDPSNAALKSTLERLKVSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1G9</accession>
    <name>A0A2S9H1G9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Response regulator of the LytR/AlgR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_1444</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93835">
        <property type="protein sequence ID" value="PRC93835"/>
        <property type="gene ID" value="S2091_1444"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007492">
        <property type="entry name" value="LytTR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04397">
        <property type="entry name" value="LytTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00850">
        <property type="entry name" value="LytTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50930">
        <property type="entry name" value="HTH_LYTTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="2"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="domain" description="HTH LytTR-type" evidence="3">
        <location>
            <begin position="130"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC93835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="234" mass="26740" checksum="B681F2C2AC82FF73" modified="2018-07-18" version="1">MKIILIDDEHLARMELRRLLAVYADCEIVAEAANIEEAQRAIEEHKPDLIFLDVQMPDGSGFDLLDQLESVPEVIFTTAFDSYALRAFEVNALDYLQKPISAERLTQALKRVRSKINEAKPALLASSSKIFIKDGERCWLVALEKIALFESEGNYTRVYFDQHRPLLLRSLNQLEQRLDATQFIRASRRFIVNLQFVEHIGPSAASGLVFTLQNGLSVEMSRRRAAEFKELSRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1K5</accession>
    <name>A0A2S9H1K5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="11">TonB family C-terminal domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">S2091_1432</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
            <orientation evidence="1">Periplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TonB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93823">
        <property type="protein sequence ID" value="PRC93823"/>
        <property type="gene ID" value="S2091_1432"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006260">
        <property type="entry name" value="TonB/TolA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037682">
        <property type="entry name" value="TonB_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03544">
        <property type="entry name" value="TonB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01352">
        <property type="entry name" value="tonB_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_C" evidence="10">
        <location>
            <begin position="147"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF03544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC93823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="222" mass="23359" checksum="567A29AFB75E67BE" modified="2018-07-18" version="1">MSSPKQAKSLQAFGLAVAVEIALVAGVALILASSATIHAAHTEPVLLTLVADETPPEKPAEPKPETKPLPVKVVTKTVAPKVPTPPTPVTTQITPPEAAVESDVQTAFAEPAPAKAAPPIPAPSTGKVDPNAEYAAQVHAAVQAAYYYPPAAAAMHFSGRVRVEFQLRDGHVVEPRVLKSCGIALFDKAALQAVQSAHYPEPPTALRGEDLHYQIWVELSTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1L5</accession>
    <name>A0A2S9H1L5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alpha/beta hydrolase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1442</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93833">
        <property type="protein sequence ID" value="PRC93833"/>
        <property type="gene ID" value="S2091_1442"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015537470" evidence="1">
        <location>
            <begin position="27"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="domain" description="AB hydrolase-1" evidence="2">
        <location>
            <begin position="47"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="294" mass="32392" checksum="0D8EC6147EDE3D20" modified="2018-07-18" version="1">MKNHFYSVVRCLASLMLFGLFCQAYAEDNVSHSVLNIQVTGSGKPMILIPGLASSGEVWDSTVAHYAKDYQCIVITLAGFAGKPAVDTPLFSSAEKELSRYISDKKLDHPIIVGHSLGGFLAMQFAAQHPEQVGKVVIVDSLPALGATQMPSVTKEQLQGAAANMRDNMRQSDPAQALASRRMAVTSMVSKPADIERVMGWGAASDRNTVINAMYELMATDLRDDIAQIKAPTLVLGTWIAYQEYAPRSAIENTFKMQYQKLPGVKIAFADTARHFIMYDDPQWMFAQMDEFLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1N3</accession>
    <name>A0A2S9H1N3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative Ig domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_1498</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93889">
        <property type="protein sequence ID" value="PRC93889"/>
        <property type="gene ID" value="S2091_1498"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005516">
        <property type="term" value="F:calmodulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007156">
        <property type="term" value="P:homophilic cell adhesion via plasma membrane adhesion molecules"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000226">
        <property type="term" value="P:microtubule cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="22"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006644">
        <property type="entry name" value="Cadg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002126">
        <property type="entry name" value="Cadherin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015919">
        <property type="entry name" value="Cadherin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011635">
        <property type="entry name" value="CARDB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016134">
        <property type="entry name" value="Dockerin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008964">
        <property type="entry name" value="Invasin/intimin_cell_adhesion"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007882">
        <property type="entry name" value="MAP6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011041">
        <property type="entry name" value="Quinoprot_gluc/sorb_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031325">
        <property type="entry name" value="RHS_repeat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14759">
        <property type="entry name" value="PTHR14759"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07705">
        <property type="entry name" value="CARDB"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05593">
        <property type="entry name" value="RHS_repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00736">
        <property type="entry name" value="CADG"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49313">
        <property type="entry name" value="SSF49313"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49373">
        <property type="entry name" value="SSF49373"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50952">
        <property type="entry name" value="SSF50952"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50268">
        <property type="entry name" value="CADHERIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51766">
        <property type="entry name" value="DOCKERIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cadherin" evidence="5">
        <location>
            <begin position="10139"/>
            <end position="10242"/>
        </location>
    </feature>
    <feature type="domain" description="Dockerin" evidence="6">
        <location>
            <begin position="11300"/>
            <end position="11361"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="2459"/>
            <end position="2497"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="2632"/>
            <end position="2725"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="2856"/>
            <end position="2926"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="2997"/>
            <end position="3031"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="6825"/>
            <end position="6864"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="7387"/>
            <end position="7411"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="8763"/>
            <end position="8782"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="8938"/>
            <end position="8963"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="8993"/>
            <end position="9015"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="9043"/>
            <end position="9071"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="9091"/>
            <end position="9111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="9190"/>
            <end position="9215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="9298"/>
            <end position="9320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="9420"/>
            <end position="9492"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="11119"/>
            <end position="11138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="2465"/>
            <end position="2497"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="9190"/>
            <end position="9213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC93889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="15885" mass="1634368" checksum="945A8F6F2B1ACFB6" modified="2018-07-18" version="1">[encoded data, 15885 characters]</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1R2</accession>
    <name>A0A2S9H1R2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1499</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93890">
        <property type="protein sequence ID" value="PRC93890"/>
        <property type="gene ID" value="S2091_1499"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="325" mass="37458" checksum="2BDB457B9F014D09" modified="2018-07-18" version="1">MSGVARFGVNPDWLRNRNAKFLQYAEILNVHNDANIASLEYYAENGETKQKKFPTAVQEVQNKRKWEDFVDSLLGKYGLYRLWNFEQTSIEKNTFDIALANSSFSATYLSQMIRLFIHFKFPARFNGRKLQMLLMDGIAYTALGILIGRNDQAFSLARLQLLAYRQGFYSKADFYPIFHFMMRILADYLGELPHIQRGESVHEPVFNALYSLWRAPDAEAIVPTCLAALDLHTYCSTYCEGEIHEFDAAWHITPIELLLMFKLRELQGLANPKIDHPLMNSPLGVLPHMTTCGSDTLMDSMRDRMQKDGFNENEIFVECYGSKKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1S7</accession>
    <name>A0A2S9H1S7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1538</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93929">
        <property type="protein sequence ID" value="PRC93929"/>
        <property type="gene ID" value="S2091_1538"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="75" mass="8203" checksum="2BF6B5BE7FACEA5D" modified="2018-07-18" version="1">MLDFQHVCFTVSSKVAHQRLGVRGPITALTKSTSGAVPRTHHQTTVSGSPVRFNIYPTIVIGIDYVIRNTWLPGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1W1</accession>
    <name>A0A2S9H1W1_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 10">Phosphoglycolate phosphatase</fullName>
            <shortName evidence="10">PGP</shortName>
            <shortName evidence="10">PGPase</shortName>
            <ecNumber evidence="5 10">3.1.3.18</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">S2091_1113</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Specifically catalyzes the dephosphorylation of 2-phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>2-phosphoglycolate + H2O = glycolate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:14369"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29805"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58033"/>
            <dbReference type="EC" id="3.1.3.18"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 10">Organic acid metabolism; glycolate biosynthesis; glycolate from 2-phosphoglycolate: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.18" evidence="5 10"/>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC93940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93940">
        <property type="protein sequence ID" value="PRC93940"/>
        <property type="gene ID" value="S2091_1113"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00865">
        <property type="reaction ID" value="UER00834"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008967">
        <property type="term" value="F:phosphoglycolate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046295">
        <property type="term" value="P:glycolate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00495">
        <property type="entry name" value="GPH_hydrolase_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041492">
        <property type="entry name" value="HAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006346">
        <property type="entry name" value="PGPase/MupP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037512">
        <property type="entry name" value="PGPase_prok"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13419">
        <property type="entry name" value="HAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00413">
        <property type="entry name" value="HADHALOGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01549">
        <property type="entry name" value="HAD-SF-IA-v1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01509">
        <property type="entry name" value="HAD-SF-IA-v3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01449">
        <property type="entry name" value="PGP_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="7 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Nucleophile" evidence="10">
        <location>
            <position position="13"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="13"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="15"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="176"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000830"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC93940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="225" mass="24414" checksum="03746E66BD6E14A2" modified="2018-07-18" version="1">MIKMNGIQAAIIDLDGTMIDTIGDFLVAINAMRAEFALAPLEQAVIQNMVGKGSENLIRQVLAVDFSPAEVERHFDAAMNSYQRNYLSINGQYSKLYPDVQEGLSALQAQGIRLACVTNKPISFALPLLKQKSLHHYFDVIYGGDCLPHKKPHPAPLLQVCSDFKLEPNQVVAIGDSSNDAIAARAAGCWALTVPYGYNHGEAVQAIDTDGIVETLLCAAHFVNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1Z9</accession>
    <name>A0A2S9H1Z9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glutathione S-transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_1161</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GST superfamily. HSP26 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC93988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93988">
        <property type="protein sequence ID" value="PRC93988"/>
        <property type="gene ID" value="S2091_1161"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03059">
        <property type="entry name" value="GST_N_SspA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034341">
        <property type="entry name" value="SspA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00043">
        <property type="entry name" value="GST_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13417">
        <property type="entry name" value="GST_N_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="SSF47616"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GST N-terminal" evidence="2">
        <location>
            <begin position="1"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="3">
        <location>
            <begin position="83"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC93988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="203" mass="23726" checksum="B5C9C58B21C586C6" modified="2018-07-18" version="1">MMVLYSGTTCPFSQRCRLVLFEKGMDFEIRDVDLFNKPEDISTMNPYGQVPILVERDLILYESNIINEYIDERFPHPQLMPADPLMRSRARLMLFNFEKELFIHVHTLENDKSGNSSKVLDKARAEIRDRLTTLAPLFIKNKYMLGEEFSMLDVAIAPLLWRLDHYGIEISKTAAPLMKYAERIFSRPAYIEALTPSEKVMRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H222</accession>
    <name>A0A2S9H222_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1208</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94035">
        <property type="protein sequence ID" value="PRC94035"/>
        <property type="gene ID" value="S2091_1208"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="33" mass="3696" checksum="376AA8A872E26CCD" modified="2018-07-18" version="1">MLSNLRFSAFDLFVATDSACFSYVVCQDVEMSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H241</accession>
    <name>A0A2S9H241_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phage envelope protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1228</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94055">
        <property type="protein sequence ID" value="PRC94055"/>
        <property type="gene ID" value="S2091_1228"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1810.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009833">
        <property type="entry name" value="DUF1398"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036696">
        <property type="entry name" value="YdfO-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07166">
        <property type="entry name" value="DUF1398"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160419">
        <property type="entry name" value="SSF160419"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0261">Viral envelope protein</keyword>
    <keyword evidence="1" id="KW-0946">Virion</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="137" mass="14989" checksum="2E4EC52D7992E03F" modified="2018-07-18" version="1">MNNAIENLKSAQQRAMAGRPKAGGFPYLAETLRSAGVKRNCWFLPSCQSFYVTELGPVAVQGTPLIEGMADVPPFNREALITALRIDQAGKSTFSEFLIASWKAGTVKYDVDLIARTVTYYGVDGESYVESYPLVDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H249</accession>
    <name>A0A2S9H249_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 12">DNA gyrase subunit B</fullName>
            <ecNumber evidence="4 12">5.6.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">gyrB</name>
        <name evidence="15" type="ORF">S2091_1211</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>ATP-dependent breakage, passage and rejoining of double-stranded DNA.</text>
            <dbReference type="EC" id="5.6.2.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="12">Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="12">Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the type II topoisomerase GyrB family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the type II topoisomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.2" evidence="4 12"/>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94038">
        <property type="protein sequence ID" value="PRC94038"/>
        <property type="gene ID" value="S2091_1211"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003918">
        <property type="term" value="F:DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006265">
        <property type="term" value="P:DNA topological change"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006261">
        <property type="term" value="P:DNA-templated DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03366">
        <property type="entry name" value="TOPRIM_TopoIIA_GyrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.670">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01898">
        <property type="entry name" value="GyrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002288">
        <property type="entry name" value="DNA_gyrase_B_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011557">
        <property type="entry name" value="GyrB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041423">
        <property type="entry name" value="GyrB_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001241">
        <property type="entry name" value="Topo_IIA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013760">
        <property type="entry name" value="Topo_IIA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013759">
        <property type="entry name" value="Topo_IIA_B_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013506">
        <property type="entry name" value="Topo_IIA_bsu_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018522">
        <property type="entry name" value="TopoIIA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006171">
        <property type="entry name" value="TOPRIM_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034160">
        <property type="entry name" value="TOPRIM_GyrB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00204">
        <property type="entry name" value="DNA_gyraseB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00986">
        <property type="entry name" value="DNA_gyraseB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18053">
        <property type="entry name" value="GyrB_insert"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01751">
        <property type="entry name" value="Toprim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00433">
        <property type="entry name" value="TOP2c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56719">
        <property type="entry name" value="SSF56719"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01059">
        <property type="entry name" value="gyrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00177">
        <property type="entry name" value="TOPOISOMERASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50880">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11 12" id="KW-0413">Isomerase</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 12" id="KW-0799">Topoisomerase</keyword>
    <feature type="domain" description="Toprim" evidence="14">
        <location>
            <begin position="452"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00019166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="PRC94038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="834" mass="92604" checksum="D293DD8CE1088681" modified="2018-07-18" version="1">MSEILPDSNQDSTPDQSQYGASSIQILEGLEAVRKRPGMYIGDTSDGTGLHHLVFEVLDNSIDESLAGHCTEIHVTIHADNSISITDNGRGIPTGIKWDDKHEPKRSAAEIVMTELHAGGKFDQNSYKVSGGLHGVGVSCVNGLSKLLKLTVRRDGKIHTMDFVRGVPQDRTIETINGLVCSPIKVIGDTDKRGTEVHFWADEEIFTHIEFHYEILAKRIRELSFLNNGVRIKLSDHRSGKEELFAFEGGTRGFVEYINKSKSVLHPTIFQATGERMSDQNTNISVDVSMQWNDAYNEQVLCFTNNIPQRDGGSHLTGLRAAMTRVINKYIEEHDYAKKAKVEVTGDDMREGLTCVLSVKVPEPKFSSQTKDKLVSSEVRGPVEEIVAKTLSDYLQERPNDAKIICGKIVEASRAREAARKARELTRRKGVMDGLGLSAKLADCQEKDPALCELYVVEGDSAGGSAKQGRDRKFQAILPLRGKVLNVEKARFEKMLSSEQITTLIATLGTSIGPDEFNIEKLRYHRIIIMTDADVDGAHIRTLLLTLFYRQMPELVERGHIYIAQPPLYKVKAGRDERYLKDDTEEASYMMTVALNNAALTPSTGAAPIEGEALAELVRQYNLANAIMLRLTRMIDRAALTAIMTGVTLQLDTAANAEMTAQAMTAAINDPSVKAIVTTDDLSERFGLRIERMYHGNVRVSSIEADFIESNDYRVLASSAATFQGLVGEGAFIRRGEGERVKESSVADFHHAMLWLRDEAERSVSKQRYKGLGEMNPSQLWETTMDPKVRRLLKVQIEDAIAADQIFTTLMGDDVEPRRAFIESNALRAGNIDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2H1</accession>
    <name>A0A2S9H2H1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="9">TonB-dependent Receptor Plug Domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_1358</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94185">
        <property type="protein sequence ID" value="PRC94185"/>
        <property type="gene ID" value="S2091_1358"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="3 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 9" id="KW-0675">Receptor</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0798">TonB box</keyword>
    <feature type="domain" description="Plug" evidence="8">
        <location>
            <begin position="61"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="7">
        <location>
            <begin position="396"/>
            <end position="973"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC94185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="975" mass="103434" checksum="C608D0F570DB1EDD" modified="2018-07-18" version="1">MMMETIMSRSLRMMFSGGVALGIGILAQPAIAQQSTDTTTAQQVQRVEITGSSIKRIVKEGALPVQVLTQADIKKTGATSVTDLIQNLPAMQGFATASTSVNGGGGGVTNAALHALPAQYTLVLLDGVRLAPQGTTNPTVNLESIPLDAIERVEILTDGASALYGSDAIAGVVNFILKKNKTDGDAYVTGQDPQHSGGRSWSAGISKGFGDLDKDNYNVLLSYSHDEQKALEASQRSFSAQGGKIPFSANGQNYIFNQTSINNAPANLVINSALPSDPNGLNPITSESNPYLIANGNCGSNANSYVHNTTCRFNYSATVQDIPSSQRDSGLAKATFNINENTTAWATMLVSRYAMTAQYAPSAQPFGITPQSYPSLYSTYVQPVLNATGTQITAANGGNATAYFRTVGMGGRTDDYQTDAHHFSAGISSTVAGWDLNGVLTISNSVEKDTSAGGYGNFNEFNALVASGAYDPFMNTGVAALQGAEITGQLLQKNTSNDNTIKVGAQHNLFEMQGGMSIISLGADFQHTSFQEQYNPLLLANSGYASQPAGAAGTNSVLGGSTAQAPFFASRNNEGLFGEWLLPITKTLEGNIAGRYDSYSKVYSGYIFETTALGGAQLPNADVGNSFSKATYKLSLRFTPIDSLLFRGSYGTGFKAPSLLDIAQTPTYANSTAGTYACPFNTPASCSGGTAANPVQYDLLQSGNPNNGSSGLKAEDSTQWTLGFRVEPGFGLTAGLDLWNVKITNQVLAAGIPEQVGFANPQLYSYLFVNPYQDPVGHYTTIAFNQVPLNGGVANYQGIDWDFAEKLKTPVGPLALAWNGTYMLKQNYTFQTNGPVLTDLGAFGPDNSVVFRVQMRAIASLTTGNFTNNLSANYKTGYQDQNYPVTDGSVQVVNADGSTTAVNYTGHVGSYTTFDWQGRYDYSKVLNFTAGIKNLFDKNPPLSLVNAGGGNQVGYDGRYTDPLGRAFYLTGHYKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2H5</accession>
    <name>A0A2S9H2H5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_1355</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94182">
        <property type="protein sequence ID" value="PRC94182"/>
        <property type="gene ID" value="S2091_1355"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031419">
        <property type="term" value="F:cobalamin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006158">
        <property type="entry name" value="Cobalamin-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025288">
        <property type="entry name" value="DUF4080"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023404">
        <property type="entry name" value="rSAM_horseshoe"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02310">
        <property type="entry name" value="B12-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13311">
        <property type="entry name" value="DUF4080"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51332">
        <property type="entry name" value="B12_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="B12-binding" evidence="3">
        <location>
            <begin position="1"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="Radical SAM core" evidence="4">
        <location>
            <begin position="162"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="480"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="481"/>
            <end position="513"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC94182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="513" mass="58151" checksum="3182E264029F53C8" modified="2018-07-18" version="1">MTILLSTLNARYSHASLGLRYLFANMGDLQASTILQEFVIGTKTTDIVEKILAHEKPDEKLIVGFGVYIWNVEELSKVVTMLKCVAPHVTVILGGPEVSYETAQQNIVQAADYVITGWGDVSFAALCQQVINGPQPLMKIHAGVQPKLDQLKLPYAHFTDHDIAHRILYVEASRGCPFKCEFCLSALDKTAWPFDLDLFLAELETLYQRGARLFKFVDRTFNLNIKSSLRIMQFFLDKLAAKPDDPVFAHFEVVPDHLPDALKTGIQQFPAGTLQFEIGIQSFNPTVQALVSRKQDNAKAAENIRWLCQHSHAHLHVDLIAGLPGEDMASFARGFNQLVTLEPHEIQFGILKRLRGTPIIRHTEEYKMVFDPNPPYTILATRDIDFNTMQRLVRFARYWDLVANSGRFNHTLKLILADDPFAHFMALSDWLYINTDATHRIAMERLAKLVSNWLQQERGLGEDEIAAQLKLDYAGQVSPEKIPRSERKKLKEEQELLGKKAAPERQARHLEAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2J3</accession>
    <name>A0A2S9H2J3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_1259</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94086">
        <property type="protein sequence ID" value="PRC94086"/>
        <property type="gene ID" value="S2091_1259"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004638">
        <property type="entry name" value="EmrB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00711">
        <property type="entry name" value="efflux_EmrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="59"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="85"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="112"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="144"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="173"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="207"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="232"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="276"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="311"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="342"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="369"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="485"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="21"/>
            <end position="507"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC94086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="511" mass="54944" checksum="6B766451A1818264" modified="2018-07-18" version="1">MTPSSDKQPLVPLHGANRSLAALTLGLASFMAVVDITIANVSVPTISGNLGISPEEGEWLITSFAVANAICIPLTGWLSRRFGQVKLFVAAVTAFTIASILCGLASSFESLLFFRILQGAVAGPIVPLSQALLVAVFPRERQTLAVAMWAMTNMAGPVVGPMLGGWITDQYSWPWIFLVNAPIGFFVVASTLKLLRGRDTPTVRLPVDVIGLALIAIAVGSLQIGLDRGRTLDWFASPMICVMAILAVLGFIVLIIWELGATHPIIDLRLFAHRNFAVGTIAIAIGFGLYFAALVLIPLWLQTNLGYSSTWAGLVTAPMGIFGIALAPFLGRWVSKNDARRFASIAFIAWAAVAFWRSTMTTQVDANTIAITCLAQGIGIGFFLTPIVSLSLIGIPPEKVAAASGLQTAIRMMSGSLMASLAQTFWDQRSRFHQTHLVSQLTPLNDYVASTISTLKQTGFSETQAWGLIARELDIQAHMLSLNDFFLLSTLLFSATLGVVWLARGPRKQTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2N3</accession>
    <name>A0A2S9H2N3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional accessory protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0863</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94242">
        <property type="protein sequence ID" value="PRC94242"/>
        <property type="gene ID" value="S2091_0863"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006139">
        <property type="term" value="P:nucleobase-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05685">
        <property type="entry name" value="S1_Tex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.650">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3500.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041692">
        <property type="entry name" value="HHH_9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010994">
        <property type="entry name" value="RuvA_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022967">
        <property type="entry name" value="S1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044146">
        <property type="entry name" value="S1_Tex"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023323">
        <property type="entry name" value="Tex-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023319">
        <property type="entry name" value="Tex-like_HTH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018974">
        <property type="entry name" value="Tex-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032639">
        <property type="entry name" value="Tex_YqgF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006641">
        <property type="entry name" value="YqgF/RNaseH-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037027">
        <property type="entry name" value="YqgF/RNaseH-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17674">
        <property type="entry name" value="HHH_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00575">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09371">
        <property type="entry name" value="Tex_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16921">
        <property type="entry name" value="Tex_YqgF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00732">
        <property type="entry name" value="YqgFc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47781">
        <property type="entry name" value="SSF47781"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S1 motif" evidence="2">
        <location>
            <begin position="663"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="734"/>
            <end position="783"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="783" mass="85794" checksum="A9BA4FB6788BC0C8" modified="2018-07-18" version="1">MLPSIEQRLAVELVAKPQQIAAAITLLDEGATVPFISRYRKEATGGLDDTQLRLLEQRLSYLRELEQRREAIVNSITEQGKMTPLLLDAIMHAEDKTGLEDLYLPYKIKRRTKAQIALEAGLLPLAEALIADPTLVPEEAATAYLKAPFKTDAGDNPGVADAKAALDGARQILMERFAEDATLLQQCRAYLQEHGIVESLVIEGKQDEGAKYADYFAYTESIMSIPSHRALAILRGRREEMLNVVLRLDTEEEKPKWDAPLNPCEGRIAHFFKISNQGRAADKWLADTVRWCWRVKVFMHLESELMGQLRERAELEAINVFALNLKALLLAAPAGQHATMGLDPGLRTGVKVAIVDATGKVLEYSTIYPHQPRNDWDGSLHTLAQLAAKHNVSLISIGNGTASRETDKLAQDLIKLRPELKLRKIVVSEAGASVYSASEFASKELPDLDVTIRGAVSIARRLQDPLAELVKIDPKSIGVGQYQHDVSQSQLAKSLDAVVEDCVNAVGVDVNTASVPLLARVSGLSNSVAQSIVNYRDTQGRFDSRAALRKVPRLGDKTFEQAAGFLRVMDGESPLDASAVHPESYPLVEKILADLKRDVKSVIGDAGLLKTLNPAKYADEKFGVPTISDILKELEKPGRDPRPEFSTATFKEGVEEIRDLRPDMILEGVVTNVAAFGAFVDIGVHQDGLVHISALSNTFVKDPHTVVKAGQVVKVKVLEVDEKRKRIALTMRLTDSAPQPGAQPVQRADRDDAKRLSQHQKQPAQAAAPANSAMAAAFAKLRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2R0</accession>
    <name>A0A2S9H2R0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phenylacetate-CoA oxygenase, PaaH subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0896</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94275">
        <property type="protein sequence ID" value="PRC94275"/>
        <property type="gene ID" value="S2091_0896"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.520">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009359">
        <property type="entry name" value="PaaB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038693">
        <property type="entry name" value="PaaB_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06243">
        <property type="entry name" value="PaaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF030200">
        <property type="entry name" value="PaaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02157">
        <property type="entry name" value="PA_CoA_Oxy2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="93" mass="10462" checksum="18A8F6BE8FBB0CFD" modified="2018-07-18" version="1">MSDAQLWEVFVRSQNGLAHRHIGSVRASDAQSALQHARDVYMRRGEGISIWLVASKYLVISPPDERAAWLASSEDKGFRLPTFFSVPEGVQYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2R2</accession>
    <name>A0A2S9H2R2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alkylhydroperoxidase AhpD family core domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0893</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94272">
        <property type="protein sequence ID" value="PRC94272"/>
        <property type="gene ID" value="S2091_0893"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051920">
        <property type="term" value="F:peroxiredoxin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029032">
        <property type="entry name" value="AhpD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004675">
        <property type="entry name" value="AhpD_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003779">
        <property type="entry name" value="CMD-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02627">
        <property type="entry name" value="CMD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69118">
        <property type="entry name" value="SSF69118"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00778">
        <property type="entry name" value="ahpD_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CMD" evidence="1">
        <location>
            <begin position="17"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="143" mass="16322" checksum="2A94493A93464632" modified="2018-07-18" version="1">MSNLRLPYNELSPELLKGFRQVKIELEKSPLGLPLIELVYMRISQINGCSYCLNLHGESLRKHDTPQRRINELAGWRVSVQFSAKEKAALQWTEALTHVSTTNAADAFYEPLKEHFSDVEISDLTFAISLMNAFNRLAIGMRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2W5</accession>
    <name>A0A2S9H2W5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0942</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94321">
        <property type="protein sequence ID" value="PRC94321"/>
        <property type="gene ID" value="S2091_0942"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015491446" evidence="1">
        <location>
            <begin position="23"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="102" mass="9863" checksum="1E5E8B6211C84AC7" modified="2018-07-18" version="1">MKSKFCATYVLAGCFLASMLSACGGGGSGSIPDSSPAVLAPGATYTMQQNNSVLVPAGTTVSANGTTVTVAGSNTTTNTTNGAVVVVPTTATGPANNTVTTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H303</accession>
    <name>A0A2S9H303_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0983</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94362">
        <property type="protein sequence ID" value="PRC94362"/>
        <property type="gene ID" value="S2091_0983"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="62" mass="7030" checksum="8982A0E52103D448" modified="2018-07-18" version="1">MQALRVEISIYGKSLSYMPSFEFLTHAAFFQSNLLSVHLIDVAIYDASEIYSTSNLLQNVEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3H0</accession>
    <name>A0A2S9H3H0_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA topoisomerase</fullName>
            <ecNumber evidence="3">5.6.2.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Omega-protein</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Relaxing enzyme</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Swivelase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Untwisting enzyme</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">S2091_1104</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP-independent breakage of single-stranded DNA, followed by passage and rejoining.</text>
            <dbReference type="EC" id="5.6.2.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the type IA topoisomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.1" evidence="3"/>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94483">
        <property type="protein sequence ID" value="PRC94483"/>
        <property type="gene ID" value="S2091_1104"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003917">
        <property type="term" value="F:DNA topoisomerase type I (single strand cut, ATP-independent) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006265">
        <property type="term" value="P:DNA topological change"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00186">
        <property type="entry name" value="TOP1Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03362">
        <property type="entry name" value="TOPRIM_TopoIA_TopoIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.460.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000380">
        <property type="entry name" value="Topo_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003601">
        <property type="entry name" value="Topo_IA_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023406">
        <property type="entry name" value="Topo_IA_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013497">
        <property type="entry name" value="Topo_IA_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013824">
        <property type="entry name" value="Topo_IA_cen_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013825">
        <property type="entry name" value="Topo_IA_cen_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013826">
        <property type="entry name" value="Topo_IA_cen_sub3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023405">
        <property type="entry name" value="Topo_IA_core_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003602">
        <property type="entry name" value="Topo_IA_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005738">
        <property type="entry name" value="TopoIII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025589">
        <property type="entry name" value="Toprim_C_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006171">
        <property type="entry name" value="TOPRIM_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034144">
        <property type="entry name" value="TOPRIM_TopoIII"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11390">
        <property type="entry name" value="PTHR11390"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01131">
        <property type="entry name" value="Topoisom_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01751">
        <property type="entry name" value="Toprim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13342">
        <property type="entry name" value="Toprim_Crpt"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00417">
        <property type="entry name" value="PRTPISMRASEI"/>
    </dbReference>
    <dbReference type="SMART" id="SM00437">
        <property type="entry name" value="TOP1Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00436">
        <property type="entry name" value="TOP1Bc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00493">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56712">
        <property type="entry name" value="SSF56712"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01056">
        <property type="entry name" value="topB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00396">
        <property type="entry name" value="TOPOISOMERASE_I_PROK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50880">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6 12" id="KW-0413">Isomerase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0799">Topoisomerase</keyword>
    <feature type="domain" description="Toprim" evidence="11">
        <location>
            <begin position="3"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00030003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00032235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00032877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PRC94483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="844" mass="94244" checksum="EB0B61D3D5143DE4" modified="2018-07-18" version="1">MTKTLIIAEKPSVASDIAKALGGFTKHDEYFESDDYVLSSAVGHLLEITVPEEYDVKRGKWSFANLPMIPPHFALNPIAKTEARLKVLTKLIKRKDVSALINACDAGREGELIFRLIAQHAKAKQPVTRLWLQSMTQNAIRDGFSRLRTDSEMLPLADAARCRSEADWLIGINGTRAMTAFNSKEGGFYLTTVGRVQTPTLSIVVEREEKIKQFVPRAYWEVRAEFVCAAGIYEGRWLDHQHKKNELDPEQRAERLWSQTAADSIVTACRNKIGVVTEESKPATQLAPALFDLTSLQREANSRFGFSAKNTLGLAQALYEKHKVLTYPRTDSRHLPEDYIASVKQTLEVISENNNYQQFSSTILNQGWVKPNKRIFDNTKISDHFAIIPTTQAPKNLSEPEQKLYDLVTRRFMAVFFPAAEFQITTRITEVSGHHFKTDGKVMTKPGWLAIYGKEMAADGEDNGTLVAVAKNEKVKTESIHGNELVTKPPARYTEATILSAMEGAGKLMDDDELRAAMTGKGLGTPATRATIIEGLLTERYLLREGRELQPTAKAFQLMTLLRGLGVDELTSPELTGGWEHKLAQMEKGQISREEFMREIAQMTQIIVKRAKEYNNDTIPGDYSTLTTPCPHCGGVVKENYRRFACTKCEFNISKTPGSRQFEVAEVEELLAKREIGPLQGFRSKMGRPFAAILKIVPDDEGTNLKLEFDFGQNQDDEDAEPVDFTGHAVLGPCPKCASNVYELGLGYVCEKTVAKPKACDFRSGRIILQQEILPEQMVKLLVDGKTDLLPGFISQRTRRPFKAFLVKAKDGKISFEFEERKPKVAGAAKKPVKKAAAKTKVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3J2</accession>
    <name>A0A2S9H3J2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0555</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94552">
        <property type="protein sequence ID" value="PRC94552"/>
        <property type="gene ID" value="S2091_0555"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="89"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="139"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="167" mass="18861" checksum="9943FFD0458B7AD1" modified="2018-07-18" version="1">MLLNLFNLFGHYFWVISIVVSLQVFWQSGAVRERCKSDVEFAIDDSKVRWKLFLWMCAPWFAMGIGQRFGGVPTVWHFLKPGDGNPWVALFFLSVFGCWLLAAYWVYLRDGANAIVEHQLIRINGLTGQVKLTPNKVKLVVALMLIGGIAAALTMFSNHMVVPIGID</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H407</accession>
    <name>A0A2S9H407_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">YceI domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0711</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94708">
        <property type="protein sequence ID" value="PRC94708"/>
        <property type="gene ID" value="S2091_0711"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007372">
        <property type="entry name" value="Lipid/polyisoprenoid-bd_YceI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036761">
        <property type="entry name" value="TTHA0802/YceI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04264">
        <property type="entry name" value="YceI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00867">
        <property type="entry name" value="YceI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101874">
        <property type="entry name" value="SSF101874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YceI" evidence="1">
        <location>
            <begin position="34"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="200" mass="21790" checksum="A17F15C3FB3A9D79" modified="2018-07-18" version="1">MTVAFKLMELNMKKLLVLIAVLGISVTALAAPEIYVIDGSHTMPRFEYNHFGYSIQLSRFDSTTGKITLDRQAKSGSVEVEILSNSVDTGSAAFNHDIQSADFLDTGTYPTINYKSTKVSFSGDVPTSVEGNLTIKGITKPVTLTITSFHCMTHPMLKKDACGANATAKINRSDFNAGKYAPYVSDEMTLIFGVESIRQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H416</accession>
    <name>A0A2S9H416_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">LysR substrate binding domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0720</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94717">
        <property type="protein sequence ID" value="PRC94717"/>
        <property type="gene ID" value="S2091_0720"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="7"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="313" mass="34870" checksum="723522AEAEF711A7" modified="2018-07-18" version="1">MTIDEAISFKKLEIFLAFMKLNNMARVSELLDISTVSVHRALHSLEEAMRCPLFKRDGRSLIPLQSAYTFAEYAQRTLDDCEEGIQKVRDAAGFNAKRLKIGSLYSLTLRCIPKLMVGLKLRKPALDIDLTLGSNRDLIDQLNAGKLDAIVIGVHTKEGLPDQPNSTLISIPLFDDDIFLAAPLRSKFSGQEKIDLTDLKSEKFVTLTEGFVTSQDFWYCFEKAGFAPDISMRVQDIFSLINLVSGGIGYSLLPGRVANFSSHIELIPLEFKFGAQQRITLLLSKARERDPNLLALAAECRLYGMGGNKDGFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H498</accession>
    <name>A0A2S9H498_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0808</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94805">
        <property type="protein sequence ID" value="PRC94805"/>
        <property type="gene ID" value="S2091_0808"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="218" mass="24817" checksum="E5673D30572C7048" modified="2018-07-18" version="1">MTMEHYLKIMDSHVHRYGIPAQVSLQGEGEPTLNHDFFNMAAHVRRIGSEPTTITNGSYKYPEHFAQSFKKIGISLDTLDPAEASRVGRHNLARVLEFIESVSSFLEVTIFTVAISPSFHAVAAWCQQRGLKHIVQPLQSKPDYNYRYPQHVVVHPRPSLYQCAYLQQDLMRYYAIDSGEFPCCFIKDARHYVSIADLKQQLANKQIPASCSGCKELK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4G1</accession>
    <name>A0A2S9H4G1_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Probable GTP-binding protein EngB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">engB</name>
        <name evidence="10" type="ORF">S2091_0769</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Necessary for normal cell division and for the maintenance of normal septation.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94766">
        <property type="protein sequence ID" value="PRC94766"/>
        <property type="gene ID" value="S2091_0769"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000917">
        <property type="term" value="P:division septum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01876">
        <property type="entry name" value="YihA_EngB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00321">
        <property type="entry name" value="GTPase_EngB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030393">
        <property type="entry name" value="G_ENGB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019987">
        <property type="entry name" value="GTP-bd_ribosome_bio_YsxC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03598">
        <property type="entry name" value="GTPase_YsxC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51706">
        <property type="entry name" value="G_ENGB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="8" id="KW-0132">Cell division</keyword>
    <keyword evidence="6 8" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 8" id="KW-0717">Septation</keyword>
    <feature type="domain" description="EngB-type G" evidence="9">
        <location>
            <begin position="23"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC94766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="233" mass="25935" checksum="BAD1731F6A4BC9E9" modified="2018-07-18" version="1">MSILWQARFFTTVNHLRNLPDLQVPELAFAGRSNAGKSTAINTLCNQKKLAFASKTPGRTQHINYFSIGGAHVAQHRKDPTIVEEIRALLVDLPGYGYAEVPGAAKNHWNELLGAYVKNRDQLSALILIMDARRPFTDLDKQMLEWFAPTGRPVHCILAKSDKLNRNDSTNALRLTQSVLASYVDENGQPFPYTVQLFSALKRVGLEEADAKIRELLGLDREPEPTVNAAVAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4I8</accession>
    <name>A0A2S9H4I8_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="14 15">Multifunctional fusion protein</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="14">Shikimate kinase</fullName>
                <shortName evidence="14">SK</shortName>
                <ecNumber evidence="14">2.7.1.71</ecNumber>
            </recommendedName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="15">3-dehydroquinate synthase</fullName>
                <shortName evidence="15">DHQS</shortName>
                <ecNumber evidence="15">4.2.3.4</ecNumber>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name evidence="14" type="primary">aroK</name>
        <name evidence="15" type="synonym">aroB</name>
        <name evidence="17" type="ORF">S2091_0789</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).</text>
    </comment>
    <comment type="function">
        <text evidence="14">Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate = 3-dehydroquinate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:21968"/>
            <dbReference type="ChEBI" id="CHEBI:32364"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58394"/>
            <dbReference type="EC" id="4.2.3.4"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 14">
            <text>ATP + shikimate = 3-phosphoshikimate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13121"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:36208"/>
            <dbReference type="ChEBI" id="CHEBI:145989"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.71"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
        <cofactor evidence="15">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="15">Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="14">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="14">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 15">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="15">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 2/7.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 14">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 5/7.</text>
    </comment>
    <comment type="subunit">
        <text evidence="14">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="15">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="14">Belongs to the shikimate kinase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 15">Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.71" evidence="14"/>
    <dbReference type="EC" id="4.2.3.4" evidence="15"/>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94786">
        <property type="protein sequence ID" value="PRC94786"/>
        <property type="gene ID" value="S2091_0789"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00053">
        <property type="reaction ID" value="UER00085"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003856">
        <property type="term" value="F:3-dehydroquinate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004765">
        <property type="term" value="F:shikimate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:cellular amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009423">
        <property type="term" value="P:chorismate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00464">
        <property type="entry name" value="SK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00110">
        <property type="entry name" value="DHQ_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00109">
        <property type="entry name" value="Shikimate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016037">
        <property type="entry name" value="DHQ_synth_AroB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030960">
        <property type="entry name" value="DHQS/DOIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031322">
        <property type="entry name" value="Shikimate/glucono_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000623">
        <property type="entry name" value="Shikimate_kinase/TSH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023000">
        <property type="entry name" value="Shikimate_kinase_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01761">
        <property type="entry name" value="DHQ_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01202">
        <property type="entry name" value="SKI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01357">
        <property type="entry name" value="aroB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01128">
        <property type="entry name" value="SHIKIMATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 15" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="11 15" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="10 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="15" id="KW-0170">Cobalt</keyword>
    <keyword evidence="5 15" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 14" id="KW-0418">Kinase</keyword>
    <keyword evidence="12 15" id="KW-0456">Lyase</keyword>
    <keyword evidence="14" id="KW-0460">Magnesium</keyword>
    <keyword evidence="15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="15" id="KW-0520">NAD</keyword>
    <keyword evidence="8 15" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 14" id="KW-0808">Transferase</keyword>
    <keyword evidence="15" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="DHQ_synthase" evidence="16">
        <location>
            <begin position="250"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <begin position="2"/>
            <end position="7"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="6"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="24"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="48"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="70"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="108"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="127"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <begin position="254"/>
            <end position="259"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <begin position="288"/>
            <end position="292"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <begin position="312"/>
            <end position="313"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="325"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="334"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="367"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="430"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="447"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005412"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF01761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="PRC94786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="547" mass="59074" checksum="10A173BDCA8A2316" modified="2018-07-18" version="1">MGAGKTTIGRALAKKLNMRFVDSDHEVEARTGVAIPVIFDIEGEASFRQREADVIRDLTAQGGIVLATGGGAILNEQNRQYLHSRGTVIYLRASVSHILQRTSHDKNRPLLRTADPRKVLDELTLQRDPLYQEIAHVVIETGRPNVAHLVQTILVQLGWPIAPASRLAKPLELTSQPTMSTQPSPTSHLLKVALGERSYPILIAPDALKQVAKYVQSNRVVIVTNSTVAPLYLARVTTSLETVGKKVEQIILPDGEAHKNMESLTFIFDALLKNKCDRRTTLLALGGGVIGDITGFAAASYMRGIPFVQIPTTLLSQVDSSVGGKTGINHPLGKNMIGAFYQPQAVIADTKSLATLPARELSAGLAEVIKYGAIIDTEFFTWLEQNCQKLRAHDEAALAYAIGRSCEIKAEVVRLDERESGLRAILNFGHTFAHAIESALGYGAWLHGEAVGCGMVMAADLSCRLGYISVSDKERIRALVAAAGLPVQAPDLGLATWLGWMQVDKKNEGGQIKFVLLKVMGRAVLESVPASVLEATLLACCTSSADI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4L6</accession>
    <name>A0A2S9H4L6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0011</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94816">
        <property type="protein sequence ID" value="PRC94816"/>
        <property type="gene ID" value="S2091_0011"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015559798" evidence="1">
        <location>
            <begin position="21"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="113" mass="12353" checksum="53D3EA8FB17714AE" modified="2018-07-18" version="1">MKPVTLLFAIIGLTAGSSFALDIELPAETAAYRPSDMPGYQLVQNNCMTCHSAQYVLSQPPSSPRSYWVATVKKMKKPFAAPIPDEEMPAIVDYLVKNYGNEKPVASVDSSKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4N2</accession>
    <name>A0A2S9H4N2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0140</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94945">
        <property type="protein sequence ID" value="PRC94945"/>
        <property type="gene ID" value="S2091_0140"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021557">
        <property type="entry name" value="DUF3016"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11454">
        <property type="entry name" value="DUF3016"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015785073" evidence="1">
        <location>
            <begin position="20"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="169" mass="19518" checksum="735FD4B51A505B96" modified="2018-07-18" version="1">MNKLLLVVAAIFISCTAFAGEVTVKWQEPEKYTDIQSGDQDKGKFEADLFKNFDSIFAELARKLPDNTVWQITVTDLDLAGEVRPSMRGSGVEMRVVKPIYRPAIMFEYKLLDAQNKVLKEAKVDLKDLGFMSRPASIIGRDRKLYPYEEYMIRQWFEQQQMQKILPGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4Q2</accession>
    <name>A0A2S9H4Q2_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">2-dehydropantoate 2-reductase</fullName>
            <ecNumber evidence="4">1.1.1.169</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Ketopantoate reductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">S2091_0160</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(R)-pantoate + NADP(+) = 2-dehydropantoate + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:16233"/>
            <dbReference type="ChEBI" id="CHEBI:11561"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15980"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.169"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; (R)-pantothenate biosynthesis; (R)-pantoate from 3-methyl-2-oxobutanoate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ketopantoate reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.169" evidence="4"/>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94965">
        <property type="protein sequence ID" value="PRC94965"/>
        <property type="gene ID" value="S2091_0160"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00028">
        <property type="reaction ID" value="UER00004"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008677">
        <property type="term" value="F:2-dehydropantoate 2-reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015940">
        <property type="term" value="P:pantothenate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013752">
        <property type="entry name" value="KPA_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013332">
        <property type="entry name" value="KPR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02558">
        <property type="entry name" value="ApbA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08546">
        <property type="entry name" value="ApbA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0520">NAD</keyword>
    <keyword evidence="6" id="KW-0566">Pantothenate biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ApbA" evidence="9">
        <location>
            <begin position="3"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="domain" description="ApbA_C" evidence="10">
        <location>
            <begin position="197"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00019465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00032024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF08546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC94965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="335" mass="35892" checksum="8594EEDA23EABE2C" modified="2018-07-18" version="1">MKISIIGAGAIGGFLAVKFAQQGHEVSVLIRGKNLLAVRENGLTLQNTDGTENKVQVHASDKIADFGQQDIVILAMKAHQVAAVAADISSLLGPDTVIVTAQNGVPWWYFQKHGGTFDGTRVEAVDPDGTVSKHLDINRIIGCIVYPACDMPAPGVIRHIEGNKFTLGEIDGSDTPRIRMLADLFRKAGFKTPVSTDIRSEIWIKLWGNVCFNPISALSHATLVDICESAPTRALAARMMSEAQMIGEKLGVNFKVSIDQRIAGAASVGKHKTSMLQDIEAGRPIELEALVGSVIEMGKITSTPTPTIDTVYALASLLATSLKQQQGQLRITSTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5A7</accession>
    <name>A0A2S9H5A7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Bacterial extracellular solute-binding protein, family 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0316</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95121">
        <property type="protein sequence ID" value="PRC95121"/>
        <property type="gene ID" value="S2091_0316"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001638">
        <property type="entry name" value="Solute-binding_3/MltF_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00497">
        <property type="entry name" value="SBP_bac_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="PBPb" evidence="2">
        <location>
            <begin position="110"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC95121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="262" mass="29637" checksum="2BC1C595936C795F" modified="2018-07-18" version="1">MNNNLKPVRLIIIAIWALLISCGNTIAAEKIEALSFYESPPYLTDPVSNAGLAADFAAYLNMALSEKYQIHLQFLPRTQVDKMMRRGDKACVLFIPSFIYNGVDNGPYLWTAPLFKDRQELISRKNHPFEFNGPASLFGVHFGAMLGHTFPQLTKDIAAGKIKVERNSSGLQSLINMLLASHLDVVTMPESSIRLMMVEDPSLSDKLWFSKQSLSEYTRHVMFQQGMEVERNDVDLVMRKMNSDPVWLAILKKYGLQPISNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSA0</accession>
    <name>A0A2S9GSA0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">HDIG: uncharacterized domain HDIG</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_4688</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000045">
        <property type="protein sequence ID" value="PRC90599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90599">
        <property type="protein sequence ID" value="PRC90599"/>
        <property type="gene ID" value="S2091_4688"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008081">
        <property type="term" value="F:phosphoric diester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021812">
        <property type="entry name" value="DUF3391"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037522">
        <property type="entry name" value="HD_GYP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006675">
        <property type="entry name" value="HDIG_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11871">
        <property type="entry name" value="DUF3391"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01966">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00277">
        <property type="entry name" value="HDIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51832">
        <property type="entry name" value="HD_GYP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HD-GYP" evidence="2">
        <location>
            <begin position="169"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="73"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="73"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC90599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="451" mass="50000" checksum="61496068A63F09F7" modified="2018-07-18" version="1">MPENTKLIAIDQVKIGMFIKLDLSWFEHSFPMSSFKITNDQQIKQLHALKLKHVRYVPEKTDLAVLRPGLNPSASNSAASATTTITPQPKGEHGAGAESDPAVPVFNNIIEAKKARFEKLQKQRNEIARCEAKFVHAATVVKNINKLIFSQPKETMLEASKLIDSIADVFLTGNDAIMHLIQQKEGSEEVYFHSLNVSVLSMMLAHEMKCTEAQIKTIGIAALFHDLGKVNIPDHINRKTTALTTAEQHIFELHGEYGLVVGQKAGMDKVVLDVIINHHEFMDGSGFPHKLKGDAIRIPTRIVTIANVYDNLCNHIDPNQSLTPHEALSLMYAHRRAQFDGAVMATLVKSLGVYPPGTLVRLSNDAVGLVMNVNVGMPLRPRILVYDDEIPKEDAIILDLSVESKDLAISASIRPGLLPRPIYDYLNPRKRVNYYVDSQSKSEKSAPAVGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSD4</accession>
    <name>A0A2S9GSD4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">YD repeat (Two copies)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_4674</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000044">
        <property type="protein sequence ID" value="PRC90606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90606">
        <property type="protein sequence ID" value="PRC90606"/>
        <property type="gene ID" value="S2091_4674"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045351">
        <property type="entry name" value="DUF6531"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031325">
        <property type="entry name" value="RHS_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006530">
        <property type="entry name" value="YD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20148">
        <property type="entry name" value="DUF6531"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05593">
        <property type="entry name" value="RHS_repeat"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01643">
        <property type="entry name" value="YD_repeat_2x"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015466625" evidence="1">
        <location>
            <begin position="21"/>
            <end position="857"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6531" evidence="2">
        <location>
            <begin position="172"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC90606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="857" mass="90711" checksum="BC1010A6D52D392E" modified="2018-07-18" version="1">MKKLFFIFVFLIFNFSPSFGQTVAPTVEYDGTPYGVIDMGTFNAACNAIPGQYAAIGNGISLSVYVVQLEQQGNPADPILGFECRAQSNSNSNSTGDFFTGVLIYAEYYCPPGSTIGGTTGANYYCTFVCPPNSRYFGDVQKCVPVVQVAAPPKAKPINNGCPICDKAKSVGDPINVGTGNSYQTQTDLTLAAPLSGLSISRTYNSSPTNPDASTVRSFGTRWTQPYDARVAPIGWATPPNMVASNIPVICWQRTDTGYIWCEYPPVPVWQVVAVTRGDGKGLYFTAPAATAGNQVWTADQGVTGQLTSTLASDGVTPTSFTFTDTDNHRELFDGNGVLLSLTSPGGTTQQLTYSTGASNDSSVGRYPATAPICPHVQAGAVVTSGTLLCVTDNWGRQLQFEHDSLGRITETIDPNGQLTQYAYDGVSAGCNAANTAQSIACSANNLTSITYPDGKTKTLYYNEAAQINGGTVCPGSAPVGNGFGYLLNALTGIVDENGTRSVSWTFDCNGIATSSQLGAGVDSYQIAVGAADVNGNNTSVVTSPLGTQTTYGFTAVNGLVVGNLVTQPAGSGSAVATSSSTYDTNGNLASHTDFNGHITNYTYDANRNLELIRTEAAGTAQARTITTSWNPTYRLPAQVAEPLRMTTYTYDTNGNLLNKTQQATTDVNGVQGVSATVTGTPRKWTYTYNSVGQVLTITGPRTDVTDLTQFAYDTYGNLSSVTNAAGQVTTLSNYDLNGHVGSITDPNGLTTTYVYSPRGWLTSQSKGSEVTSYNYDGVGQLISVTFPNQAKLTYTYDTAHRLTNIADNLGNTVNYTLDAMGNRTLEQVNDTSGNLARQISRVVDALNRLQQITGAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSE8</accession>
    <name>A0A2S9GSE8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Integral membrane protein, TerC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_4657</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TerC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000041">
        <property type="protein sequence ID" value="PRC90649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90649">
        <property type="protein sequence ID" value="PRC90649"/>
        <property type="gene ID" value="S2091_4657"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005496">
        <property type="entry name" value="Integral_membrane_TerC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022369">
        <property type="entry name" value="Integral_membrane_TerC_rswitch"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30238:SF0">
        <property type="entry name" value="PTHR30238:SF0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03741">
        <property type="entry name" value="TerC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03718">
        <property type="entry name" value="R_switched_Alx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="42"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="84"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="115"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="143"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="206"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="236"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="268"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="293"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC90649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="320" mass="35404" checksum="DCACD003AE5DF1B3" modified="2018-07-18" version="1">MMHTIAQPWMWGAFIAFVIAMLVVDIVACGGSRAHKMSAKHALGWSLVWVSLAMLFALGMWLILSKNVGAEIANATTMEFLAGYVIEKSLSIDNIFVFLLIFSHFSVPAEYQRKVLLYGVIGAIVMRIGMILGGVWLVEEFSWVLYVFGLFLIITGIKMMISAEAEPDLNSNPVVRFAKKILPLTADFKGEKFSVIENGKRVFTPLLLVLILIEVSDVVFAVDSIPAIFAVTTDPFIVFTSNIFAIMGLRALYFLLADMAERFHFLKYGLALVLMFVGIKMLIVDWWHVPTMASLLVIGGIVAGSVMISLLVTKKGEPKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSH1</accession>
    <name>A0A2S9GSH1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4622</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000039">
        <property type="protein sequence ID" value="PRC90672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90672">
        <property type="protein sequence ID" value="PRC90672"/>
        <property type="gene ID" value="S2091_4622"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009351">
        <property type="entry name" value="YcaQ-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06224">
        <property type="entry name" value="HTH_42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC90672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="405" mass="46624" checksum="B763B0E17AA22290" modified="2018-07-18" version="1">MMADNPTLKLSAARNLHLAAQGLLTPPAKNATKKQLLATIRQMAALQIDTINVVARSPYLVLWSRLGSYETVWLNELLEEGKLFEYWSHEACFLPIEDYYLYRHQMIAPHGLGWKFNQRWLLENKKEVELVRKQIHSNGASRSLDFAKRDGKAGGWWEWKPEKRSLEVLFTMGELMVAKRHNFQRVYDLRERVHPKWEDQHDLIHPLECQRQQVLLAVKALGCAKATWITDYFRMAKLDASNQAAALAEQGLLLTANVAGWDTPVYVHPDHADLLEQAAEGNLKATATQILSPFDPVVWDRKRAIELFDFDYKLECYTPAEKRRYGYFSLPILRRGAIIGRMDAKAHRQQGRFEVKSLHMEAEVKISATLVRDVIGSITKFAQWHGTPELDLSSLKTTEFYHNNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSL8</accession>
    <name>A0A2S9GSL8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4607</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000038">
        <property type="protein sequence ID" value="PRC90714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90714">
        <property type="protein sequence ID" value="PRC90714"/>
        <property type="gene ID" value="S2091_4607"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC90714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="38" mass="4196" checksum="BD0B9EF3832D1554" modified="2018-07-18" version="1">MRTLVDIPGWQIDGLAYQEKAAPNGKGTVQFWVSVFGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSM9</accession>
    <name>A0A2S9GSM9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Bacterial regulatory protein, tetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_4591</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000038">
        <property type="protein sequence ID" value="PRC90698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90698">
        <property type="protein sequence ID" value="PRC90698"/>
        <property type="gene ID" value="S2091_4591"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="8"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="31"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC90698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="217" mass="24490" checksum="E05DB0EC72A681A5" modified="2018-07-18" version="1">MTKTTPTNPTRLALLEHGKTMARQHGLRSITVRGLCQETAINTGSFVYHFGSRDQFIAELIEYWYAPLFEQIQWQQNHHADPLTRLHAMLRQLLSFVNANGAFIAQLMQDVVAGEIAAQRFTSTLAPRHPRILLQCIADAQQAGQLCIAPPLHQAMFLMSACGIPILLQHVLSGKELLPELLQQAIKQFATDPQHIDQRLQWALQGLMPNSKEFLHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSN1</accession>
    <name>A0A2S9GSN1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_4555</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000037">
        <property type="protein sequence ID" value="PRC90729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90729">
        <property type="protein sequence ID" value="PRC90729"/>
        <property type="gene ID" value="S2091_4555"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18808">
        <property type="entry name" value="SF1_C_Upf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045055">
        <property type="entry name" value="DNA2/NAM7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041679">
        <property type="entry name" value="DNA2/NAM7-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041677">
        <property type="entry name" value="DNA2/NAM7_AAA_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025103">
        <property type="entry name" value="DUF4011"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887">
        <property type="entry name" value="PTHR10887"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13086">
        <property type="entry name" value="AAA_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13087">
        <property type="entry name" value="AAA_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13195">
        <property type="entry name" value="DUF4011"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_11" evidence="1">
        <location>
            <begin position="1307"/>
            <end position="1391"/>
        </location>
    </feature>
    <feature type="domain" description="AAA_12" evidence="2">
        <location>
            <begin position="1415"/>
            <end position="1607"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC90729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="1766" mass="198273" checksum="8BDB7324A88B12C3" modified="2018-07-18" version="1">MLDAEDLLSKTNSSENKKTFELKVEIISSPTVSYAAIQNRVPIIQKILIENNFDHTLKNVDLVISSNPPFMLGQRFQFERLLAGESRTIGVELLDIHPDHNYFSELNEAELGHIEAKATAEDDSTAHSVEPIEMLAFNEWGGTKGLPELLAAFVQPNSISIDRILGLSSEILRNSNAALSMDGYQSKNRERVWKQVNAIFNALISQEIKYAPPPASFETAGQKIRTTERILDGLVSTCLDSAILMAACFEQAGLNPVVFLNKGHAWVGVWLIDTCFPTSIIDSVQSVRKRVDSGELLMLEATAISQNSRPSMQWSRITANVYIEEDSTTFTYAVDIKRARQAHIRSLKEKNPSIDQEKIVDENEGNRLPSIEAMPSLPPLDPGLLPITDVGSVDTPQGRLIRWRGKLLDLTLRNKLLNFKPGKTFLKIVCSDAAKLEDTLCKSNEFRLSGKPTLMEDGDPRSAEIYLRETGMSVSEAHANTTLLNNELVFDVPLKEFDGRLTDIFRAGKNTLEETGANTLYISIGMLDWKEALDSESTLKAPLILVPITLKRGAVGAGIKLVRHDDETIFNPTLLQKLMLDFEINLPFSDGQLPTDESGVDVSTILQQVRMAVADLKGFEVRTDCFLGNFSFTKYVMWKDLTSRVDDLSKSQIVNHLINNTGQAFIDGAKSISPSDLDTLYSPQSLFTPLIADSSQLAVVCTATNGKNIVVEGPPGTGKSQTITNMISHYLANDKTVLFVAEKMAALEVVHKRLTSLGLADFCLELHSSKAKKSEIAKEFVQTLNISQHNLQSDWLKEAEKLSVIRNQLTDLVNVLHREHRNGLSVFDSMGSCIGNSDRIPAQFNWADADTHSNAELESLYELVAEMSALARHLGNIGGHPLSEIGQTKWTPSWQDDLIKQCESIESAIVNLKLSISDFSKLLNVDVQTLSFNDLISLDQLAEILMQSCEIPFQSVSFADNQIIRKQLNDLIAHGINRNDIWTKFEESYVPDLKSISAEKLQSEWRVSNQYFILKRWISKRKITSQIKQFNLTNQRLANEEIDEFLIELRKLNEEDIFAHENRDIGKKVLGEEFKGITTDWNAAKKYLTWMESFSNVTHKLCITQSEELIQKRSHLLNLINKQPEMFSVNSNYFKVAAQLRNSFRDFANNWHELSLFASPRKALCNGENSPGILISSSSMVASWKRAKTQLQPWCVWQLNKTKSSSLGLQGLVNSVEAGEVSLDDLVPFFEFSYKNWWVKKIIDNEALLSNFSGATHEHKIFEFKKIDANFQKLTQEYIVAKLRGKIPRENEIKGELSSEIAFLRREAQKQRQHKSIRQVINQAKQTLPRVKPCLLMSPLSVAQYLDAGHPQFDVVIFDEASQIPTWDAVGAIARGKQLVCVGDPKQLPPTNFFNAADSDGVVNEDDIEEMESILDECLSIGMMTCTLDWHYRSKSEGLITFSNMQYYENRLITFPSPVTEDQSVTFVDIGGIYDAGKSRTNRKEADAIVDAVVEHYLSGKGKSHSVGVITFNAPQQSLIEKLIDAKRMEIPKFEIAISDSQVEPYFVKNLENVQGDERDVILFSITFGKDINGKTSMNFGPMNKEGGHRRLNVAASRARYQVKIFSSLRPEHIDLSRTKARGVADLKAYLDFAINGPRVLAKQALPTGREPDSPFEVAVINKLRDNGWEVHPQVGVSGYRLDLAVVNPHARGRYLLGVECDGATYHSAANARDRDRLRQMILEGLGWNIHRIWSTDWWINPEIPMKKLLDKLNQLEQIAAADNDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSU0</accession>
    <name>A0A2S9GSU0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Flagellar protein export ATPase FliI</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">S2091_4528</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000036">
        <property type="protein sequence ID" value="PRC90780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90780">
        <property type="protein sequence ID" value="PRC90780"/>
        <property type="gene ID" value="S2091_4528"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045261">
        <property type="term" value="C:proton-transporting ATP synthase complex, catalytic core F(1)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030257">
        <property type="term" value="C:type III protein secretion system complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044780">
        <property type="term" value="P:bacterial-type flagellum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071973">
        <property type="term" value="P:bacterial-type flagellum-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030254">
        <property type="term" value="P:protein secretion by the type III secretion system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020003">
        <property type="entry name" value="ATPase_a/bsu_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004100">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000194">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_nucl-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005714">
        <property type="entry name" value="ATPase_T3SS_FliI/YscN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020005">
        <property type="entry name" value="FliI_clade1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040627">
        <property type="entry name" value="T3SS_ATPase_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00006">
        <property type="entry name" value="ATP-synt_ab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02874">
        <property type="entry name" value="ATP-synt_ab_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18269">
        <property type="entry name" value="T3SS_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03496">
        <property type="entry name" value="FliI_clade1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01026">
        <property type="entry name" value="fliI_yscN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00152">
        <property type="entry name" value="ATPASE_ALPHA_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="12" id="KW-0966">Cell projection</keyword>
    <keyword evidence="9" id="KW-0139">CF(1)</keyword>
    <keyword evidence="12" id="KW-0969">Cilium</keyword>
    <keyword evidence="12" id="KW-0282">Flagellum</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-1278">Translocase</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="AAA" evidence="11">
        <location>
            <begin position="190"/>
            <end position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PRC90780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="469" mass="50114" checksum="50635489ED2D645D" modified="2018-07-18" version="1">MNTEATPLPSLALCKTYLNNAKEVIELVGNFDIAGRITRVTGLVIEAVGLKLPMGSACIIALQNGEEINAEIVGFDNEKVFLMPQNSVEGLLPGTPVFAAKATDSICPVNLTIRPSRRAVDRTRHLPVGYELLGRVLDGAGKPLDSLGPLNTTQSAALKSRSINPLHRAPITEILDVGVRAINSMLTIGRGQRMGLFAGSGVGKSVLLGMMARYTSADVIVVGLIGERGREVKEFIEQILGAQGLARSVVVAAPADTPPLMRLQGAAYATTIAEFFRDQGKSVLLIMDSLTRYAMAQREIALAIGEPPATKGYPPSVFAKLPLLVERAGNSLPGGGSITAFYTVLTEGDDQQDPIADAARAILDGHIVLDRTLADSGHYPAIDIEQSISRAMTNIASPSHQKAARKLKQLVSRYQHSRDLISVGAYSAGTDPVLDEAILNHLKIEHFLQQGIQERSSITESLGQLTTLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSW0</accession>
    <name>A0A2S9GSW0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cytochrome C oxidase subunit II, periplasmic domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_4475</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000035">
        <property type="protein sequence ID" value="PRC90812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90812">
        <property type="protein sequence ID" value="PRC90812"/>
        <property type="gene ID" value="S2091_4475"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004129">
        <property type="term" value="F:cytochrome-c oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002429">
        <property type="entry name" value="CcO_II-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028096">
        <property type="entry name" value="EfeO_Cupredoxin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13473">
        <property type="entry name" value="Cupredoxin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="SSF49503"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50857">
        <property type="entry name" value="COX2_CUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015517237" evidence="2">
        <location>
            <begin position="21"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="COX2_CUA" evidence="3">
        <location>
            <begin position="30"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC90812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="122" mass="13331" checksum="164CC8087EE9C9CA" modified="2018-07-18" version="1">MLIGSFASLAALLLGGKLNAQELAAAKLQKKERVIKITAKKFSYSPNQITIKEGEHVVLELTSLDFMHGFNIPDLTIRADLLPGQSTKIHLGALKEGKYEFLCDNFCGNGHEEMNGTLIVTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GT22</accession>
    <name>A0A2S9GT22_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4419</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000034">
        <property type="protein sequence ID" value="PRC90838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90838">
        <property type="protein sequence ID" value="PRC90838"/>
        <property type="gene ID" value="S2091_4419"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC90838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="166" mass="19482" checksum="A444FFAF05A5A407" modified="2018-07-18" version="1">MKMFRLFIKNLLILSLLLFVVAGCDNLFVKERSCGFSFDMRFDDQHAAVLDYKLWGEKNLIDGVPKEYLDKRMKFYGEGIGFQYDRPISLYVKWQGDITGSIYEKTVDLRHVMPRNLEGTDLYFIVHGPQIYVYLALKESYVRGAQRIGTRYLDRTNIQLYPNPSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GT88</accession>
    <name>A0A2S9GT88_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4409</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AHA1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000033">
        <property type="protein sequence ID" value="PRC90916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90916">
        <property type="protein sequence ID" value="PRC90916"/>
        <property type="gene ID" value="S2091_4409"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013538">
        <property type="entry name" value="Activator_of_Hsp90_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08327">
        <property type="entry name" value="AHSA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="139" mass="16186" checksum="796D6B0F94DAF0CA" modified="2018-07-18" version="1">MESKHKIITVQATINCPIQKAWEFWTSPEHIVQWNHATKDWHTTRAENDLRVDGKFLYRMEAKDGSMGFDFLGSYKAVIRHELIEYQIGDGRLVEIVFSSDGNQTKIVESFEAEAIHSHEMQQQGWQAILTNFKKFAEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTJ5</accession>
    <name>A0A2S9GTJ5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4221</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000030">
        <property type="protein sequence ID" value="PRC91033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91033">
        <property type="protein sequence ID" value="PRC91033"/>
        <property type="gene ID" value="S2091_4221"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019670">
        <property type="entry name" value="DUF2523"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10734">
        <property type="entry name" value="DUF2523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="65"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="103" mass="11158" checksum="4C4AC0BE94946416" modified="2018-07-18" version="1">MPILAILVRFIWGGLAIVLPSLVGRVLLALGIGFVTYKGFNIGTDFLMNLIKNNLSGMPSDITSFLAWCWVDKALALMFSSFTASLAIKTAQGSLTKMVFKAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTY6</accession>
    <name>A0A2S9GTY6_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">FGE-sulfatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_4170</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000028">
        <property type="protein sequence ID" value="PRC91169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91169">
        <property type="protein sequence ID" value="PRC91169"/>
        <property type="gene ID" value="S2091_4170"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005532">
        <property type="entry name" value="SUMF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042095">
        <property type="entry name" value="SUMF_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03781">
        <property type="entry name" value="FGE-sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="SSF56436"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FGE-sulfatase" evidence="2">
        <location>
            <begin position="48"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="254"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="264"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="286" mass="32127" checksum="2BB94ABA2ADFF9F1" modified="2018-07-18" version="1">MKLIVSVIALLLLGVAGFLGYRALMWQLSTTPVDLHAGTVFRDCRICPEMVVIPQTDRFMMGQSDTGRKDPVEGFMFGEDTTRAPEHPVRIAQFALGRMEITQRQWESLMDSDPSMEKKCGLDCPVEHVSWLDVQEFLRRFNAKIGQHYRLPSEAEWEYAATAGQAPSDATLQEQIGDDASWNQYNSQFTTHPVGSKKANGFQVHDMIGNVWEWVEDCDHRDYNGAPANGRAWIDDPSLPKQCRSGYRVVRGGSCISPTRTPRDRGAAPEDRHGADLGFRVARDLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GU43</accession>
    <name>A0A2S9GU43_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Excise: DNA binding domain, excisionase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_4116</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000027">
        <property type="protein sequence ID" value="PRC91221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91221">
        <property type="protein sequence ID" value="PRC91221"/>
        <property type="gene ID" value="S2091_4116"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041657">
        <property type="entry name" value="HTH_17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010093">
        <property type="entry name" value="SinI_DNA-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12728">
        <property type="entry name" value="HTH_17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01764">
        <property type="entry name" value="excise"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="70"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="197" mass="21844" checksum="D218C57EE17834C0" modified="2018-07-18" version="1">MQSDHSDEIMSTRDAAKCLGVSVRTVQLWVESGSLQAWKTPGGHRRIFRQSVNEMLAARTAMPNVSEFFEILICSGDATAVSLMEEQLTALGSQVRIRKVSNGFEALIQMGERCPNLLITDLFMPNMDGLQMLKALQNTAFVQTMKIIVASELHEDEEVEKRGGFPPGVTKFSKSAPFDQLLSLVTDYIDVSKTQSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GU48</accession>
    <name>A0A2S9GU48_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4042</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000026">
        <property type="protein sequence ID" value="PRC91257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91257">
        <property type="protein sequence ID" value="PRC91257"/>
        <property type="gene ID" value="S2091_4042"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="59" mass="6896" checksum="F10AAE7AC87D4E76" modified="2018-07-18" version="1">MALHVAWHLLKRDLNEGLQMQQLKSDTCGTVTYPSIKHFLKLVEENFSPLCKSNRRKIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUB8</accession>
    <name>A0A2S9GUB8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3972</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000025">
        <property type="protein sequence ID" value="PRC91301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91301">
        <property type="protein sequence ID" value="PRC91301"/>
        <property type="gene ID" value="S2091_3972"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="113"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="154"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="230" mass="22249" checksum="C1C15746F2434A1C" modified="2018-07-18" version="1">MSISALGNNQQIAYAQFFSGQSVNNQNSGGNSTAPANNQGNGNSFFSAISNALAQLGVGTASSASTSSAAAAATSTNSASTSPSATTSETPQQALSAFVQNLFAAIQAQVSGQSSSGSASGSTTGVTGHHHHHGGGEGKLESGIQDLIQQLGASSSSSSASSSSTGAGGTGTSSSNSANSTLAALQTSFNNLLSTDGISSTGTSLSGFLQSLSQNLQGSTTSGNVVSTHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUC4</accession>
    <name>A0A2S9GUC4_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">UPF0246 protein S2091_3981</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3981</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0246 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000025">
        <property type="protein sequence ID" value="PRC91310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91310">
        <property type="protein sequence ID" value="PRC91310"/>
        <property type="gene ID" value="S2091_3981"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00652">
        <property type="entry name" value="UPF0246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005583">
        <property type="entry name" value="YaaA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30283">
        <property type="entry name" value="PTHR30283"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03883">
        <property type="entry name" value="H2O2_YaaD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00652"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="262" mass="29932" checksum="D495F428AFED692E" modified="2018-07-18" version="1">MLIALSPAKSLDYNTPIPHSDAIQLSLPTFMPQAARLISLLKKQNSLELMQLMGISESLAQLNKERYAAWVKSPSLEQGKAAIFAFNGDVYEGLDAYSLNLKQLNYVQKHTRILSGIYGVLRPFDLLQAYRLEMGTRLTNPKGANLYAFWGDTIADNLRAVLSEHKEQVVINLASDEYFKSVRLPALKAEVITPVFQDWKNDRYKIISFYAKRARGLMARYCAQHQITNPEQLKQFDLDGYAYDADNSDQQRWMFRRRLAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUE0</accession>
    <name>A0A2S9GUE0_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 15">Succinyl-diaminopimelate desuccinylase</fullName>
            <shortName evidence="15">SDAP desuccinylase</shortName>
            <ecNumber evidence="5 15">3.5.1.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14 15">N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="primary">dapE</name>
        <name evidence="17" type="ORF">S2091_3995</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 15">
            <text>H2O + N-succinyl-(2S,6S)-2,6-diaminoheptanedioate = (2S,6S)-2,6-diaminoheptanedioate + succinate</text>
            <dbReference type="Rhea" id="RHEA:22608"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:57609"/>
            <dbReference type="ChEBI" id="CHEBI:58087"/>
            <dbReference type="EC" id="3.5.1.18"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <cofactor evidence="15">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
        <text evidence="15">Binds 2 Zn(2+) or Co(2+) ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 15">Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; LL-2,6-diaminopimelate from (S)-tetrahydrodipicolinate (succinylase route): step 3/3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 15">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 15">Belongs to the peptidase M20A family. DapE subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.18" evidence="5 15"/>
    <dbReference type="EMBL" id="PUGF01000025">
        <property type="protein sequence ID" value="PRC91324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91324">
        <property type="protein sequence ID" value="PRC91324"/>
        <property type="gene ID" value="S2091_3995"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00034">
        <property type="reaction ID" value="UER00021"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050897">
        <property type="term" value="F:cobalt ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009014">
        <property type="term" value="F:succinyl-diaminopimelate desuccinylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019877">
        <property type="term" value="P:diaminopimelate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01690">
        <property type="entry name" value="DapE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001261">
        <property type="entry name" value="ArgE/DapE_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005941">
        <property type="entry name" value="DapE_proteobac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="SSF55031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01246">
        <property type="entry name" value="dapE_proteo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00759">
        <property type="entry name" value="ARGE_DAPE_CPG2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 15" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="13 15" id="KW-0170">Cobalt</keyword>
    <keyword evidence="11 15" id="KW-0220">Diaminopimelate biosynthesis</keyword>
    <keyword evidence="9 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12 15" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="8 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 15" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="M20_dimer" evidence="16">
        <location>
            <begin position="175"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="active site" evidence="15">
        <location>
            <position position="68"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="15">
        <location>
            <position position="133"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="66"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="99"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="134"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="162"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="348"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001246"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00031891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="PRC91324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="376" mass="40890" checksum="BAAB410DD50DFD06" modified="2018-07-18" version="1">MSKTLKLTEQLISLESVTPSDLGCQQLMIDMLTPLGFVCESIESGNVSNLWARKGTTQPLIVFAGHTDVVPTGPLGKWVSDPFVPTIRHGMLYGRGAADMKSSIAAMLVAAEEFIQQHPEHPGSIGFLITSDEEGPATDGTVVVCDLLKQRGEQLDFCVVGEPTSSQHFGDTIKNGRRGSMSGKLVIHGIQGHIAYPQLAQNPIHRSAPAITELTQEVWDQANEYYLPTSFQISNIQAGTGASNVIPGHLNIDFNFRFSTASTAQSLQERVHAILDKHDLNYDLEWTIGGQPFLTPKGTLSDALSRAILSETGIHTELSTTGGTSDGRFIAQICPQVIEFGPINASIHKIDEHIAVSEIEPLKNIYRKTLENILLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUE3</accession>
    <name>A0A2S9GUE3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3992</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000025">
        <property type="protein sequence ID" value="PRC91321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91321">
        <property type="protein sequence ID" value="PRC91321"/>
        <property type="gene ID" value="S2091_3992"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015493991" evidence="2">
        <location>
            <begin position="22"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="73"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="99" mass="11349" checksum="661894FE83F2BA01" modified="2018-07-18" version="1">MTSFRSLLCCFLSVLSYSAWADGALQTENKMTDRNEHQLHKSEKMAGRANLSASNENTSKNPNAQFIPPVHQKKPLSKEEKQALRRQVNETENKYPKRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUP8</accession>
    <name>A0A2S9GUP8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3846</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000023">
        <property type="protein sequence ID" value="PRC91431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91431">
        <property type="protein sequence ID" value="PRC91431"/>
        <property type="gene ID" value="S2091_3846"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="51" mass="5740" checksum="C719931FAA388502" modified="2018-07-18" version="1">MTESYLYGGAQSAQIGQVYYKPNFIPYQPPPYPSYATEQTTGISVIYNLKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUR4</accession>
    <name>A0A2S9GUR4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Nucleotidyl transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_3753</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000022">
        <property type="protein sequence ID" value="PRC91475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91475">
        <property type="protein sequence ID" value="PRC91475"/>
        <property type="gene ID" value="S2091_3753"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005835">
        <property type="entry name" value="NTP_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00483">
        <property type="entry name" value="NTP_transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0129">CBS domain</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="CBS" evidence="3">
        <location>
            <begin position="2"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="3">
        <location>
            <begin position="68"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC91475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="346" mass="38356" checksum="2A66CE1364A1D9B1" modified="2018-07-18" version="1">MLIKDLEQFVISDSATIHDAMQAIENNWREIVMVQNQNEVIIGIITDGDIRRGLLKGLTMDSLASTVMSSGYISVALKTDRSAVLDLMKALRIRHVPVVDVDKHLLGIHFLEEIIGTNKRPNAAVIMAGGKGTRLRPYTEACPKPMVKVAGRPILERIILNLVGNGICHIFVSINYLGHMIEEHFGDGRDFGCQIEYLRETTELSTGGALSLLPDTLQDPIIVLNGDQVTRINVQALLACHTESGADATISVGHYQHEVPYGVVHQLDGHLVRLEEKPALDILINLGIYVLNPSVLQLVPKNQFFLITDLYAQLLLKNKTIATYFSEEDWIDVGRPDDLKRANGLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GV89</accession>
    <name>A0A2S9GV89_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glyoxalase-like domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3692</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000021">
        <property type="protein sequence ID" value="PRC91576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91576">
        <property type="protein sequence ID" value="PRC91576"/>
        <property type="gene ID" value="S2091_3692"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004360">
        <property type="entry name" value="Glyas_Fos-R_dOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00903">
        <property type="entry name" value="Glyoxalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="5"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="121" mass="13548" checksum="A880C717BEF51356" modified="2018-07-18" version="1">MSIISFEIISVPVSDQSKSKHFYQEILGFELIREESMGPAMQWIQLAPKGCATTIALVTWLEKMPPGGLQGVMLNVTDIDQDHATLSARGVQLSEIRQEPWGRYSMFNDPDGNGWILRQAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVB2</accession>
    <name>A0A2S9GVB2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Acetoacetyl-CoA reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_3576</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000020">
        <property type="protein sequence ID" value="PRC91638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91638">
        <property type="protein sequence ID" value="PRC91638"/>
        <property type="gene ID" value="S2091_3576"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018454">
        <property type="term" value="F:acetoacetyl-CoA reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042619">
        <property type="term" value="P:poly-hydroxybutyrate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011283">
        <property type="entry name" value="Acetoacetyl-CoA_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01829">
        <property type="entry name" value="AcAcCoA_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC91638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="246" mass="26528" checksum="90C2567820091C28" modified="2018-07-18" version="1">MKKRIAYVTGGMGGIGSSICKRLCKDGFTVVAGCGPNSMRRETWLKAMRDEGYDVHASEGNVSDWYSTKEAFEKVRAEIGEVDVLVNNAGITRDGQFRKMSHEDWDIVINTNLNSLFNVTKQVIDGMVERGWGRVINISSVNGQKGQFGQTNYSTAKAGLHGFTMALAQEVATKGVTVNTVSPGYVGTDMVKAIRPDVLEKIVSGIPVKRLAEPDEIASIVAWIASNEGGYATGSDFSINGGLHMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVC0</accession>
    <name>A0A2S9GVC0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Universal stress protein family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3613</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal stress protein A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000020">
        <property type="protein sequence ID" value="PRC91675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91675">
        <property type="protein sequence ID" value="PRC91675"/>
        <property type="gene ID" value="S2091_3613"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006015">
        <property type="entry name" value="Universal_stress_UspA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006016">
        <property type="entry name" value="UspA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00582">
        <property type="entry name" value="Usp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01438">
        <property type="entry name" value="UNVRSLSTRESS"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Usp" evidence="2">
        <location>
            <begin position="159"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="277" mass="29974" checksum="D8420F49E6640A89" modified="2018-07-18" version="1">MTYKTILVHIDDTSRSPSRIQLAAQLAMKQDAHLLAIADTGVSRFIYQDGNINGVDPSLLSHLEYLRERATQNVVDFKIQAAKLGVTSFSSEITQDDACGGIGLRARYCDLVIVGQTNPDEASPAVMDDFPEYMILNSGRPVLIIPYAGDFNQPGKRPLIAWDGSRAATRAITDAIPLLRTADLVNVAIVNPKGDTHGEQPGADIAAYLARHGIKLDVSVHNTKLNTGNALLSLASDLNSDLMVMGGYGHSRFREMIMGGATRTILESMTIPTLMSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVG9</accession>
    <name>A0A2S9GVG9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative NAD(P)H quinone oxidoreductase, PIG3 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3639</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000020">
        <property type="protein sequence ID" value="PRC91701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91701">
        <property type="protein sequence ID" value="PRC91701"/>
        <property type="gene ID" value="S2091_3639"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05276">
        <property type="entry name" value="p53_inducible_oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014189">
        <property type="entry name" value="Quinone_OxRdtase_PIG3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02824">
        <property type="entry name" value="quinone_pig3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PKS_ER" evidence="1">
        <location>
            <begin position="11"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="328" mass="34602" checksum="1642F98786E1C4E6" modified="2018-07-18" version="1">MMRAIEISQPGGPEVLRICERAIPVLRAGEVLIKVHAAGINRPDVFQRKGAYPAPAGASDLPGLEVAGEVVAGELSGSGFALGDMVCALVAGGGYAEYCAAPLAQCLPVPHGFTAVQAAALPETFFTVWSNVFDRAGLTGSETLLVQGGTSGIGVAAIQMATALGHKVIATAGSDEKCRACEELGAIRGINYKTENFEEVVHSLTGGRGVDVVLDMVAGDYVNRELTCMADDGRLVVIALLGGAKAQLDMGAILRRRLTVTGSTLRARSVEFKQVIAQKLHQKIWPLLESGKIKPVIYKTFSFEQASEAHVLMESSEHIGKIVLDFCV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVI7</accession>
    <name>A0A2S9GVI7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Bacterial regulatory protein, tetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3488</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000019">
        <property type="protein sequence ID" value="PRC91733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91733">
        <property type="protein sequence ID" value="PRC91733"/>
        <property type="gene ID" value="S2091_3488"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="8"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="31"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="194" mass="21348" checksum="BF22B359F409A060" modified="2018-07-18" version="1">MKHFSEISPTAVRVVDAAEGLVQQHGYNGFSYDDVAQLVGIKKPSIHHHFPKKEELVAVVAQRYTHRFREALLSIEGQHAKAPDRLIAYAALFERTFAKDRRLCVCGMLGAESDSLPEAVASEVERFFKVNLEWLKLVVADGQRAALITSKSTAEVLAEAFLCALEGAMVVGRGMRSSRGPTEVGNTFLFSVLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVJ5</accession>
    <name>A0A2S9GVJ5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Membrane transporter of cation and cationic drug</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_3504</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000019">
        <property type="protein sequence ID" value="PRC91749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91749">
        <property type="protein sequence ID" value="PRC91749"/>
        <property type="gene ID" value="S2091_3504"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042221">
        <property type="term" value="P:response to chemical"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000390">
        <property type="entry name" value="Small_drug/metabolite_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045324">
        <property type="entry name" value="Small_multidrug_res"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30561">
        <property type="entry name" value="PTHR30561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00893">
        <property type="entry name" value="Multi_Drug_Res"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="26"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="58"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="84"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC91749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="109" mass="11684" checksum="192A16B35DB6C3B0" modified="2018-07-18" version="1">MHYVYLGVAILAEVIATSFLKASDGFQRLIPSLVVIVGYCIAFYFLSLTLKTISVGIAYALWSGIGVVLIVVVSYFLYQQKLDLPGVIGVALIVAGVVVLNVFSTSVSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVS7</accession>
    <name>A0A2S9GVS7_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">Flagellar hook protein FlgE</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_3383</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Bacterial flagellum basal body</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the flagella basal body rod proteins family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000018">
        <property type="protein sequence ID" value="PRC91827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91827">
        <property type="protein sequence ID" value="PRC91827"/>
        <property type="gene ID" value="S2091_3383"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009425">
        <property type="term" value="C:bacterial-type flagellum basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.98.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011491">
        <property type="entry name" value="Falgellar_hook_FlgE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037058">
        <property type="entry name" value="Falgellar_hook_FlgE_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001444">
        <property type="entry name" value="Flag_bb_rod_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019776">
        <property type="entry name" value="Flagellar_basal_body_rod_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020013">
        <property type="entry name" value="Flagellar_FlgE/F/G"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010930">
        <property type="entry name" value="Flg_bb/hook_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037925">
        <property type="entry name" value="FlgE/F/G-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07559">
        <property type="entry name" value="FlaE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00460">
        <property type="entry name" value="Flg_bb_rod"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06429">
        <property type="entry name" value="Flg_bbr_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117143">
        <property type="entry name" value="SSF117143"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03506">
        <property type="entry name" value="FlgEFG_subfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00588">
        <property type="entry name" value="FLAGELLA_BB_ROD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0975">Bacterial flagellum</keyword>
    <keyword evidence="9" id="KW-0966">Cell projection</keyword>
    <keyword evidence="9" id="KW-0969">Cilium</keyword>
    <keyword evidence="9" id="KW-0282">Flagellum</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flg_bb_rod" evidence="6">
        <location>
            <begin position="3"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="domain" description="FlaE" evidence="8">
        <location>
            <begin position="177"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="domain" description="Flg_bbr_C" evidence="7">
        <location>
            <begin position="347"/>
            <end position="424"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF06429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF07559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC91827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="425" mass="43367" checksum="BC8434B4FFBAB527" modified="2018-07-18" version="1">MAFDQGLSGLQAASTQLDVIGNNIANSSTVGFKESNIEFADVYANSLGGGGASAVGIGVSASDVSQQFTQGTISTDSNPLDIAIDGNGFFQVSTNGSIGYTRSGEFQLNENGAIVTSSGANLQGYNANANGVLNTGVTTNIVINSANLPPKITATVGTELNLNSSSPVLLSAGFDSTKPATYTYSTSVTVYDSLGNSHALQTYYVNNGIVAPSVEDQWSVFATVDGKPIGYTPPAAPVSVATLSFNSAGTLDPATTTPVTAPPFSVPLTIPLANGATTPQVVTISYTGTTQYGVSSGVNSQTQDGFASGQLTQFSAGADGVITGTYSNGQTQTLGQIVLDNFVNPSGLKSIGNNLWLASPTSGVPLLGTPGSGSLGTLQSDAVEDSTTDLTSELVNMITAQQDYQANAQTIKTEDQIIQTLVTLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVU7</accession>
    <name>A0A2S9GVU7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acetyltransferase (GNAT) family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3403</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000018">
        <property type="protein sequence ID" value="PRC91847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91847">
        <property type="protein sequence ID" value="PRC91847"/>
        <property type="gene ID" value="S2091_3403"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="9"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="168" mass="19189" checksum="5C85F8C8F544D196" modified="2018-07-18" version="1">METGKLNSYHFRQVKAQDLQRCYDIESSAYEGDEAATREKIALRIDQYPQGFLVMEQAGKIVGFINSGCAHEVTMSDHEFKELIGHDPLSLNVVIMSVVVAPEHQGKGLATMLMHQFVQQTRDMGKKTIHLMCKERHVKLYGQLGFRYVRLSDSEHGGMAWHEMMMDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVV3</accession>
    <name>A0A2S9GVV3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3541</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000019">
        <property type="protein sequence ID" value="PRC91786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91786">
        <property type="protein sequence ID" value="PRC91786"/>
        <property type="gene ID" value="S2091_3541"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="298" mass="33313" checksum="6DA08425C19AC50D" modified="2018-07-18" version="1">MILRHIRYLLAVVEHGNFTRAAESLYVSQPTLSQQIKQLEEQLGVQLLDRSGRLVRATDAGEAYLNFARKALRELDAGQRAIHDVGDLTRGTLRLAMTPTLTSYLVGPLIAEFTTRHPGIRLHINEMPLDTIETALLDDQVDLGIAFSQVRSPEIDCRILFDEKLSVVVGKQHPFAQRSAPITANELEQELLALLTPNFATRNYVDAYFQQQGISPNIVIEANTINAIVEIVRRGNIATILPDALTRENELLRNINLTPALPHRTVALLRRKDAYQSSAALAFTQLLDEMIDSALFDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVV7</accession>
    <name>A0A2S9GVV7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3397</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000018">
        <property type="protein sequence ID" value="PRC91841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91841">
        <property type="protein sequence ID" value="PRC91841"/>
        <property type="gene ID" value="S2091_3397"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="46"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="79"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="109"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="132" mass="14341" checksum="8805EC578593B046" modified="2018-07-18" version="1">MTENYSLRIQAAYLGKVMIGLLVLTGLGFASSIVDAANLSKPVKDGAFVALILAALTIPFLIGAVYRRMDELQRRLHEQACMFSPSVSFSAAFVAGILQSHQVVPEFSAFWICACVIASWGLSLVIADRQFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVY5</accession>
    <name>A0A2S9GVY5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_3426</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000018">
        <property type="protein sequence ID" value="PRC91870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91870">
        <property type="protein sequence ID" value="PRC91870"/>
        <property type="gene ID" value="S2091_3426"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02809">
        <property type="entry name" value="alpha_hydroxyacid_oxid_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012133">
        <property type="entry name" value="Alpha-hydoxy_acid_DH_FMN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000262">
        <property type="entry name" value="FMN-dep_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037396">
        <property type="entry name" value="FMN_HAD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01070">
        <property type="entry name" value="FMN_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000138">
        <property type="entry name" value="Al-hdrx_acd_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51349">
        <property type="entry name" value="FMN_HYDROXY_ACID_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0288">FMN</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FMN hydroxy acid dehydrogenase" evidence="6">
        <location>
            <begin position="7"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="267"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="33"/>
        </location>
        <ligand>
            <name>glyoxylate</name>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="86"/>
            <end position="88"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="115"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="141"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="143"/>
        </location>
        <ligand>
            <name>glyoxylate</name>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="169"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="178"/>
        </location>
        <ligand>
            <name>glyoxylate</name>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="243"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="265"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="267"/>
        </location>
        <ligand>
            <name>glyoxylate</name>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="270"/>
        </location>
        <ligand>
            <name>glyoxylate</name>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="298"/>
            <end position="302"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="321"/>
            <end position="322"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000138-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000138-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC91870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="378" mass="40168" checksum="C5C10A638ED5E1D8" modified="2018-07-18" version="1">MIPILQTVPPHLVTLADHETHALGLLDANARAYFSGGAGDEYTLRANQQAWNQISLRPRVLRSLVGGHTRINLLGRTLAHPILLAPVAFQRLAHNDGELASAYAAAMQGAGFILSTQASVALEVIAQAIRDEPQRGPLWFQLYWQHDKTLTQQLVQRAEQAGYEALVLTVDAASSGVRDRERRAGFTLPDSVFAANLAGFPAPPPVILEPGQSALFDGLLRHAPTWDDIGWLQSITSLPILLKGIMHEEDARLAQQHGVAGIIVSNHGGRTLDTVAATATLLPQIRAAVGSDFIVLVDGGIRRGTDLLKAVALGADAVLLGRPAIYGLRNAGAIGVAHVLRLLRDELEVAMALCGCAVLADVTSAVICAGRTEAPICS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GW65</accession>
    <name>A0A2S9GW65_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3309</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000017">
        <property type="protein sequence ID" value="PRC91967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91967">
        <property type="protein sequence ID" value="PRC91967"/>
        <property type="gene ID" value="S2091_3309"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002818">
        <property type="entry name" value="DJ-1/PfpI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020449">
        <property type="entry name" value="Tscrpt_reg_HTH_AraC-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01965">
        <property type="entry name" value="DJ-1_PfpI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00032">
        <property type="entry name" value="HTHARAC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="107"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="domain" description="HTH araC/xylS-type" evidence="2">
        <location>
            <begin position="226"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="354" mass="39191" checksum="33E7D6321072A7CE" modified="2018-07-18" version="1">MLNSNTKKKSKLSVGFVLSPNFTLLAFSAFVDTLRLAADDGDRSRPIHCEWTVLSHEMRPIKASCGIEIMPTSQLTDPSKFDYIVMVGGLLNALQLPTALENYLKQAAAANVPLIGICTGSFVLARLGLMQGRRSCVSWYVHSEFTNEFPDLKVSSDELFIDDVDRLTCAGGTSVVHLAAYLVDRHCEKSRAAKALRIMIEHAPLPAKTPQPQPLFTKETNNIRVRKAMLLMERHLSDPLPAEFIAQHVNVSVRHLERLFQTELGMSPLALAFELRLNNAYNLLITTNNSIIDIALQCGFLSNSHFSRCFRKFHGKTPSLVREEALSTGNTGFSVPRSRSLNPSKNIAISAALI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWK3</accession>
    <name>A0A2S9GWK3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3238</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000016">
        <property type="protein sequence ID" value="PRC92103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92103">
        <property type="protein sequence ID" value="PRC92103"/>
        <property type="gene ID" value="S2091_3238"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007838">
        <property type="entry name" value="Cell_div_ZapA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036192">
        <property type="entry name" value="Cell_div_ZapA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042233">
        <property type="entry name" value="Cell_div_ZapA_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34981">
        <property type="entry name" value="PTHR34981"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05164">
        <property type="entry name" value="ZapA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102829">
        <property type="entry name" value="SSF102829"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="103" mass="11096" checksum="613FA9524711675E" modified="2018-07-18" version="1">MSQIDVTIMGQSYKLSCNEGGQAALMQAAVYLDEKMCALRDAAKLKGTDRIAVMAALTISAELLATKGPVGPFSELTMAEVKKQILDMNDVLDEALTPQENLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWR5</accession>
    <name>A0A2S9GWR5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Pseudouridine synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3057</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92141">
        <property type="protein sequence ID" value="PRC92141"/>
        <property type="gene ID" value="S2091_3057"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120159">
        <property type="term" value="F:rRNA pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000455">
        <property type="term" value="P:enzyme-directed rRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1560">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.580">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042092">
        <property type="entry name" value="PsdUridine_s_RsuA/RluB/E/F_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006145">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000748">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluB/E/F"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020094">
        <property type="entry name" value="TruA/RsuA/RluB/E/F_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00849">
        <property type="entry name" value="PseudoU_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01479">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00363">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00093">
        <property type="entry name" value="TIGR00093"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S4" evidence="2">
        <location>
            <begin position="9"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="252" mass="28600" checksum="59D3F311B847BDFA" modified="2018-07-18" version="1">MNTPNNEPLRLSKRMSELGLCSRREADEWISRGWVRVDGKVVSELGTKILPDQHITIERQAAAEQSKRVTVLINKPVGYVSGQAEDGYEPAICMVTVENRWEEDKLPIHFHPTQLRSLVPAGRLDIDSTGLLVLTQDGRIAKHLIGQDTSVEKEYLVRVSYSKGGTLPDADLKRLNHGLWLDGKALLPAKVRWQNEDQLNFILKEGKKRQIRRMCEAVGLTVIGLKRVRIGRVKLGNLPEGKWRYLSETEMF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWS4</accession>
    <name>A0A2S9GWS4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">BON domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3085</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92169">
        <property type="protein sequence ID" value="PRC92169"/>
        <property type="gene ID" value="S2091_3085"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007055">
        <property type="entry name" value="BON_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04972">
        <property type="entry name" value="BON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50914">
        <property type="entry name" value="BON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015423435" evidence="1">
        <location>
            <begin position="24"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="domain" description="BON" evidence="2">
        <location>
            <begin position="36"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="103" mass="10933" checksum="EC11C25C1540F6DD" modified="2018-07-18" version="1">MKNFKLASSVIVTVLFSTLAACSSTPTHESTGQYVDDTVITTNVKAAILGEPSLKVAEITVKTYKGEVQLSGFVGSVDNIRTAIAVAEKIDGVKLVKNEMTLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWT8</accession>
    <name>A0A2S9GWT8_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="8 18">Succinate dehydrogenase flavoprotein subunit</fullName>
            <ecNumber evidence="7 18">1.3.5.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">S2091_3100</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21 22">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 18">
            <text>a quinone + succinate = a quinol + fumarate</text>
            <dbReference type="Rhea" id="RHEA:40523"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="EC" id="1.3.5.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 18">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="5 18">Carbohydrate metabolism; tricarboxylic acid cycle; fumarate from succinate (bacterial route): step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4 18">Cell inner membrane</location>
            <topology evidence="4 18">Peripheral membrane protein</topology>
            <orientation evidence="4 18">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Membrane</location>
            <topology evidence="3">Peripheral membrane protein</topology>
            <orientation evidence="3">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6 18">Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.5.1" evidence="7 18"/>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92184">
        <property type="protein sequence ID" value="PRC92184"/>
        <property type="gene ID" value="S2091_3100"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00223">
        <property type="reaction ID" value="UER01005"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008177">
        <property type="term" value="F:succinate dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022900">
        <property type="term" value="P:electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.700.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003953">
        <property type="entry name" value="FAD-binding_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003952">
        <property type="entry name" value="FRD_SDH_FAD_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037099">
        <property type="entry name" value="Fum_R/Succ_DH_flav-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015939">
        <property type="entry name" value="Fum_Rdtase/Succ_DH_flav-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030664">
        <property type="entry name" value="SdhA/FrdA/AprA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027477">
        <property type="entry name" value="Succ_DH/fumarate_Rdtase_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011281">
        <property type="entry name" value="Succ_DH_flav_su_fwd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014006">
        <property type="entry name" value="Succ_Dhase_FrdA_Gneg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11632">
        <property type="entry name" value="PTHR11632"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00890">
        <property type="entry name" value="FAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02910">
        <property type="entry name" value="Succ_DH_flav_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46977">
        <property type="entry name" value="SSF46977"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56425">
        <property type="entry name" value="SSF56425"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01816">
        <property type="entry name" value="sdhA_forward"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01812">
        <property type="entry name" value="sdhA_frdA_Gneg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00504">
        <property type="entry name" value="FRD_SDH_FAD_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="18" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="18" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="13 18" id="KW-0249">Electron transport</keyword>
    <keyword evidence="12 18" id="KW-0274">FAD</keyword>
    <keyword evidence="11 18" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="15 18" id="KW-0472">Membrane</keyword>
    <keyword evidence="14 18" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 18" id="KW-0813">Transport</keyword>
    <keyword evidence="10 18" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="FAD_binding_2" evidence="19">
        <location>
            <begin position="18"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="domain" description="Succ_DH_flav_C" evidence="20">
        <location>
            <begin position="470"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="16">
        <location>
            <position position="295"/>
        </location>
    </feature>
    <feature type="modified residue" description="Tele-8alpha-FAD histidine" evidence="17">
        <location>
            <position position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00008040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00012792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00019965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR611281-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PIRSR" id="PIRSR611281-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="RuleBase" id="RU362051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF00890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF02910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="PRC92184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="596" mass="65069" checksum="1C0E645135A9B2E4" modified="2018-07-18" version="1">MAEAKPILKSTIPTRRFDAVIVGAGGSGMRASLQLAEAGLNVAVLSKVFPTRSHTVAAQGGIGASLGNMSEDNWYWHMFDTVKGSDYLGDQDAIEFMCREAPKVVYELEHFGMPFDRNADGTIYQRPFGGHTANFGEKPVQRACAAADRTGHALLHTLYQRNVSARTQFFVEWMALDIIRNEDGDVLGVIALEMETGELMILEGKTTIFATGGAGRIFAASTNAFINTGDGLGMAARAGLPLEDMEFWQFHPTGVAGAGVLITEGVRGEGGILVNSEGERFMERYAPTLKDLAPRDFVSRSMDQEIKEGRGCGPNKDHVMLDLRHIGAETIEKRLPSILEIAHKFANVDATKEPIPVVPTIHYQMGGIPTNIHGQVVAPKDGQPNAIVNGMYAIGECACVSVHGANRLGTNSLLDLLVFGRAAGNHIIAADLKAQEHKPLPANAADKALARLNALENSSGTEKVQDVANAIRSAMQRYCGVFRTDELLQQGYKEIMVIAERCKNVSFKDKSKVFNTARVEALELDNLIETAKATITSAAARKESRGAHAHRDYSARDDENWMKHTLWYSEGNRLDYKPVQTKPLTVDTFKPKPRTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWV5</accession>
    <name>A0A2S9GWV5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Bacterial extracellular solute-binding protein, family 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3121</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92205">
        <property type="protein sequence ID" value="PRC92205"/>
        <property type="gene ID" value="S2091_3121"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001638">
        <property type="entry name" value="Solute-binding_3/MltF_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00497">
        <property type="entry name" value="SBP_bac_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="PBPb" evidence="2">
        <location>
            <begin position="43"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="271" mass="30895" checksum="9BD2C03C22642C03" modified="2018-07-18" version="1">MECILSSRHSTTNRIAFLLIFFVVSLQFVSDANAQQWLKITLTEQEYPPLIIHGNGTEGVLTEIVRESFKLAKVEAVFTSVPNNRAITGLMQGLYEGSYGWAHSRERDAKLIYSSKPIYFLRIVFFQRSGEGLEWNSLTDLAQYTIGVTMGNYYSDEFESLSASGALHTDPAPSDISNFKKLLIGRIHLFPIDQDVGLFLLKNNFSQEERKKITFQRKAISIIPVYLVVRRNLPQAQELRDRFDQGYQQLADSGQLEKILALHKSQLLLQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GX08</accession>
    <name>A0A2S9GX08_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lactonase, 7-bladed beta-propeller</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2916</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92257">
        <property type="protein sequence ID" value="PRC92257"/>
        <property type="gene ID" value="S2091_2916"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019405">
        <property type="entry name" value="Lactonase_7-beta_prop"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10282">
        <property type="entry name" value="Lactonase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015562508" evidence="1">
        <location>
            <begin position="22"/>
            <end position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="436" mass="42664" checksum="7F320F0859817682" modified="2018-07-18" version="1">MNLSIKNLLVLLACCGTLLLAGCKGKSTTNNYNIKVTVSGLVGGGVVLQDNLADNLAITGNGVFTFASQLSSNSTYSVTMLTSPSLPAQSCTLANATGTVASSDVTNITLTCVAPEFAYVASSGGSSVATYIINATNGALSSAGPSVTTGNSPVAFAMDPTGRFAFVANSTDKSISSYLGNLTTGLLVSAGPAVLLSNAPNALAVDPLSKFLLVTAGNSIVSYTFNANGVLSSAGTATTGNAPSGIAVISNSSNEYAYVTNGTDNTISGYSVNAAGVLTSLGVVAATGNKPSAISAAPNGAYVYVTNSTDGTISSYPVTATGTLGVATTVASGGNAPVSIAVSASGKIAYVANSTSNNVAAFSISAAGALSSIGTATTGNTPSSVSVDPSGAFVYVVNSTDNNISVYQLTATGALPATVTVLSVGSTPVSVVTAVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GX10</accession>
    <name>A0A2S9GX10_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative esterase of the alpha-beta hydrolase superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_3154</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92238">
        <property type="protein sequence ID" value="PRC92238"/>
        <property type="gene ID" value="S2091_3154"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002641">
        <property type="entry name" value="PNPLA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01734">
        <property type="entry name" value="Patatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="SSF52151"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51635">
        <property type="entry name" value="PNPLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="1 2" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015711399" evidence="3">
        <location>
            <begin position="19"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="domain" description="PNPLA" evidence="4">
        <location>
            <begin position="64"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXSXG" evidence="2">
        <location>
            <begin position="95"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="DGA/G" evidence="2">
        <location>
            <begin position="213"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="2">
        <location>
            <position position="97"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC92238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="325" mass="33926" checksum="7DDFEEAAD97B1BC9" modified="2018-07-18" version="1">MRRIPLFFIAFVILLLSACKTPDPIASTGPASPVPQATKVATIEPLPLALPFIKPIPKHIKIGLALGGGAARGFAHVGVIKALESQGIEVEVVAGTSAGSLVGALYAAGNDGYALQKIALNMDESTISDWIVPLFAKSTGVLKGEGLQNFVNKEVHQVPIEKLKKTFGAVATDLNTGQAILFRRGNTGAAVRASSAVPGVFQPVKVGDHLYVDGGLVAPVPVAFARGMGADFVIAVNISAQPGTEASASSLNVLMQTFSIMGQTINQHELKGADIVIRPELDGMKGSDFAGRNMAIMAGERAAMLAMPEIKRKIKELQDKSVAGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GX86</accession>
    <name>A0A2S9GX86_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Periplasmic binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_2979</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the leucine-binding protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92320">
        <property type="protein sequence ID" value="PRC92320"/>
        <property type="gene ID" value="S2091_2979"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028081">
        <property type="entry name" value="Leu-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000709">
        <property type="entry name" value="Leu_Ile_Val-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13458">
        <property type="entry name" value="Peripla_BP_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00337">
        <property type="entry name" value="LEUILEVALBP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015603205" evidence="3">
        <location>
            <begin position="21"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="domain" description="Peripla_BP_6" evidence="4">
        <location>
            <begin position="28"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC92320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="376" mass="40879" checksum="78175102C073FAEE" modified="2018-07-18" version="1">MKISIYLTMLLFSMSALCHAENGVTSNTITIGQSAAFTGPAQQLGIGMRDGALAYFDHINSQGGVNGRQIKLISLDDGYNPDNAAANTHQLIDKENVFSLFGYVGTPTSNAALPLVTGAEIPFFGALTGAQSLREPFNRYIFNIRASYFEETEKIIQHSTTLSLNRIAVFYQNDAYGKAGLEGITRALKLRKIDVLAVATVERNSVDVAKAVEQIKKANPQAVVIISPYKSCAAFIKEMKKDNTVSPIFWNISFVGTQALSSELGAEGRGVMISQVVPAPGVEITAIVKEYRKLYLTKPDRQADFVSLEGFIAAKTFVEGLKRAGNSLTRTSFIHALEGMNKYDAGGFEIKFSPTNHNGSHFVDLTVIGKDTKLMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXD1</accession>
    <name>A0A2S9GXD1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Chloride channel protein EriC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_3027</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92368">
        <property type="protein sequence ID" value="PRC92368"/>
        <property type="gene ID" value="S2091_3027"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005247">
        <property type="term" value="F:voltage-gated chloride channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014743">
        <property type="entry name" value="Cl-channel_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001807">
        <property type="entry name" value="Cl-channel_volt-gated"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00654">
        <property type="entry name" value="Voltage_CLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00762">
        <property type="entry name" value="CLCHANNEL"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81340">
        <property type="entry name" value="SSF81340"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="54"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="146"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="183"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="216"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="260"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="337"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="378"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC92368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="432" mass="46519" checksum="5C97211CD8F22F72" modified="2018-07-18" version="1">MKNPFRFEQIALLPYMAKWLALASLVAVLAGTASALFLFSLDIVTAWRLAHPPIIWLLPVAGFMVGWIYLHLGKNVEAGNNLIIDEIHDPKKVIPLRMAPLVLIGTITSHLFGASVGREGTAVQMGASLADQCTHVFRLAKKQRRILIMAGISAGFASVFGTPLAGAIFGLEVLMIGRMRYDAILPCFIAAIIADQVGLLLGVHHTHYVVSDIPAISVWSLTATLIAGILFGMVGMLFANATHGLSDFMKKHIRYAPLRPFIGGTIVAVAVYALGTQRYIGLGIPTIIESFQQPLPWHDFLGKMAFTITSLGTGFKGGEVTPLFYIGATLGNALAPLLHLPFPMLAALGFVAVFAGAANTPIASTVMAIELFGPTIGSYAALACVISYVFSGHTGIYRAQRVGHSKHRYLPEGLKLSELDAYRKRRGQQSDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXG7</accession>
    <name>A0A2S9GXG7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SnoaL-like domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2773</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92398">
        <property type="protein sequence ID" value="PRC92398"/>
        <property type="gene ID" value="S2091_2773"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037401">
        <property type="entry name" value="SnoaL-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13474">
        <property type="entry name" value="SnoaL_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SnoaL-like" evidence="1">
        <location>
            <begin position="14"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="141" mass="15641" checksum="2EFA1B173A037257" modified="2018-07-18" version="1">MHAPLLSSADETEAAFYDALSRADIEALMALWAEDEEIVCVHPGSSRLVGHATIRASFEAIFERGSVNIQPVQLHASRNMMTAVHNIIEEVQRTPEMTQDIHILCTNVYIKTALGWRITLHHASVAPGRAPSELFRASMLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXM1</accession>
    <name>A0A2S9GXM1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Pyridine nucleotide-disulfide oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2852</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92477">
        <property type="protein sequence ID" value="PRC92477"/>
        <property type="gene ID" value="S2091_2852"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041854">
        <property type="entry name" value="BFD-like_2Fe2S-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017224">
        <property type="entry name" value="Opine_Oxase_asu/HCN_bsu"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037495">
        <property type="entry name" value="Opine_OX_OoxA/HcnB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyr_redox_2" evidence="1">
        <location>
            <begin position="9"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="423" mass="45418" checksum="66B075377A0BDE67" modified="2018-07-18" version="1">MKQIQQHTDILILGSGPAGLAAADAAASSEQSVTVLDDNFAPGGQIWRGGPTQWSDARAKVLWQKLITCTNVHFLYEVKVVAAPRINTLLLETPQGACSITYNRLIICSGARELLLPFPGWTLPGVTGAGGLQALIKGGLSVAGKRIAIAGTGPLLLAVAATVQRQGGQIVLIAEHRSTMELTRFILNLARSHRGKLMQAIPLLARLWSCSYRHATTVLQAHGDNQLQSISYLQNEKTVQLDCDYLACGYGLVPNLELAKLLTCEVQNNRVVVNDNQQTSQAHIWAAGEVTGIGGVDKALAEGRIAGLSASHQTASDKEQKTRNHTRQFAALLEHSFAPTDALRLLCQPTTLVCRCEDVGAQQLTIHPDWRSAKLATRCGMGACQGRICGAACEYLYGWQAPGLREPLFPSTAATLAYEPTCP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXY6</accession>
    <name>A0A2S9GXY6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="10">TonB-dependent Receptor Plug Domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">S2091_2626</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92571">
        <property type="protein sequence ID" value="PRC92571"/>
        <property type="gene ID" value="S2091_2626"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="3 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 10" id="KW-0675">Receptor</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="2 6" id="KW-0798">TonB box</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015605188" evidence="7">
        <location>
            <begin position="26"/>
            <end position="1014"/>
        </location>
    </feature>
    <feature type="domain" description="Plug" evidence="9">
        <location>
            <begin position="70"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="8">
        <location>
            <begin position="385"/>
            <end position="1013"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC92571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="1014" mass="109350" checksum="CD7DB106172F8368" modified="2018-07-18" version="1">MLNQKITFKKRIIAQALFMAFGAVALVNTAQAQALAQTTDSKNADSTLDNSQPVHRVEVTGSNIKRMDAEQASPVTIVTKQEIQQMGANTLQEILAHVSQAVPDLTDSQSMFSATEGASDANLRGLGPEATLVLLNGRRLSNYGTAYGGQYQFVNIDTIPADAIERVEILTDGASAIYGSDAVAGVINVITKKSYVGTEMHASATAVPKTSNNHEYNAGISYGFGDIDQDKFNIYGTLNVFDREAVYQNQILNVLNPTWLSYNPTFIEGFHGNNGSGPGVINPGTQFTYTAAGATIRQPSPGCPTPVMPGTPAQQTPLNTVCALNSLDLGNNWIPSSRRLNLFVNGHYEFNNSLEGFIELSGTMVKLETQLSPPNLYSGGVWSWYARNTGFNLNTFAFPYLSPTNPFNVVANNPALQGNMGGVAGLNYTLLDDPKFSRHTDTDDEYRIVAGLRGTLENKWEWESAVTLAGTHGDLESQGYNPSPAGITAAFGPYSTVNTPSGSYQVISDHPAYQLGVTNASNLALMQQMFPYFSYESWDEIFNWDGKVSGKIGQLGGGDLMFAAGANLNHEYLNSPGATNAANGQIAWQGGSWYEGSRTTEAAYAEIVAPITKRLEIDAAIRDDKYPDFANHIVPKLGVLYKAADSLALRATFSQGFRAPSLAESGTGGIYQQTVVNDPVRCAETNAIITTLSKSPNPQDVQQAQTLQSSSQCTGTVAGGITTPNPQLKPETANIANFGLIFNPVKQFDFSADYWIIDRKNEIVQNNPNTLVANGSATSPGGIPGVFVRGALTPGDLATNNMVATECAANPSLCTGGVPSYQYGNVAGVINSYINQTQSLFDGFDINANAHLDLSGYGKLDFGWKGTIKHRMDSLGNNPAWVGNQVGTYLSPRITGVFSTVWHYQQVDLSLMANYIGPQSILSAFPNGAFSNVAACESNFNTTTALCENGLASSLYWTGNVNWHPTKQVTLNFNIQNLFAHAPQYDPQAWMGINQFEFPYMSGRIYKLTASYKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXZ8</accession>
    <name>A0A2S9GXZ8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Bifunctional protein RfaE, domain I</fullName>
            <ecNumber evidence="2">2.7.1.-</ecNumber>
            <ecNumber evidence="2">2.7.7.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2591</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.-" evidence="2"/>
    <dbReference type="EC" id="2.7.7.-" evidence="2"/>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92536">
        <property type="protein sequence ID" value="PRC92536"/>
        <property type="gene ID" value="S2091_2591"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016773">
        <property type="term" value="F:phosphotransferase activity, alcohol group as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01172">
        <property type="entry name" value="RfaE_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011913">
        <property type="entry name" value="RfaE_dom_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="SSF53613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02198">
        <property type="entry name" value="rfaE_dom_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PfkB" evidence="1">
        <location>
            <begin position="3"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="298" mass="32427" checksum="54E4F5B7E69FC9D0" modified="2018-07-18" version="1">MLVVGDVMLDRYWFGEVNRISPEAPVPIVRIDRREERLGGAANVARNAAALGITTSLLGVVGEDEAGNIVEGLLRDSQINSYLNRDKHISTIIKLRVIGRQQQLIRVDFEEAPTEGVLRDKLSQYNTLLPEHNVVILSDYAKGSLVNVRDMIASGIALKKTILVDPKGSDFAPYTGASILTPNKSELRQVIGDWKSEAELTEKAQNLRRHLNIQALLVTRSEEGMSLYTEGLTHHVPTMAREVFDVSGAGDTVIATLGAMLASGKDLLEAVEIANRAAGIVVGKLGTATVTHDELFPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GY23</accession>
    <name>A0A2S9GY23_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Pyridoxine 5'-phosphate synthase</fullName>
            <shortName evidence="2">PNP synthase</shortName>
            <ecNumber evidence="2">2.6.99.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">pdxJ</name>
        <name evidence="3" type="ORF">S2091_2666</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>1-deoxy-D-xylulose 5-phosphate + 3-amino-2-oxopropyl phosphate = H(+) + 2 H2O + phosphate + pyridoxine 5'-phosphate</text>
            <dbReference type="Rhea" id="RHEA:15265"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57279"/>
            <dbReference type="ChEBI" id="CHEBI:57792"/>
            <dbReference type="ChEBI" id="CHEBI:58589"/>
            <dbReference type="EC" id="2.6.99.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; pyridoxine 5'-phosphate biosynthesis; pyridoxine 5'-phosphate from D-erythrose 4-phosphate: step 5/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homooctamer; tetramer of dimers.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PNP synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.99.2" evidence="2"/>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92611">
        <property type="protein sequence ID" value="PRC92611"/>
        <property type="gene ID" value="S2091_2666"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00244">
        <property type="reaction ID" value="UER00313"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033856">
        <property type="term" value="F:pyridoxine 5'-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008615">
        <property type="term" value="P:pyridoxine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00003">
        <property type="entry name" value="PNPsynthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00279">
        <property type="entry name" value="PdxJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004569">
        <property type="entry name" value="PyrdxlP_synth_PdxJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036130">
        <property type="entry name" value="Pyridoxine-5'_phos_synth"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30456">
        <property type="entry name" value="PTHR30456"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03740">
        <property type="entry name" value="PdxJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63892">
        <property type="entry name" value="SSF63892"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00559">
        <property type="entry name" value="pdxJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 2" id="KW-0664">Pyridoxine biosynthesis</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="1-deoxy-D-xylulose 5-phosphate binding" evidence="2">
        <location>
            <begin position="17"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="region of interest" description="3-amino-2-oxopropyl phosphate binding" evidence="2">
        <location>
            <begin position="221"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="51"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="78"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="2">
        <location>
            <position position="199"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="15"/>
        </location>
        <ligand>
            <name>3-amino-2-oxopropyl phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:57279"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="26"/>
        </location>
        <ligand>
            <name>3-amino-2-oxopropyl phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:57279"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="53"/>
        </location>
        <ligand>
            <name>1-deoxy-D-xylulose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:57792"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="58"/>
        </location>
        <ligand>
            <name>1-deoxy-D-xylulose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:57792"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="108"/>
        </location>
        <ligand>
            <name>1-deoxy-D-xylulose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:57792"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="200"/>
        </location>
        <ligand>
            <name>3-amino-2-oxopropyl phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:57279"/>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="2">
        <location>
            <position position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="260" mass="28305" checksum="74BA842EA7E281BA" modified="2018-07-18" version="1">MTIHDRIHMLELGINIDHVATLRNARGTTYPDPIQAALMAEHAGADVITLHMREDRRHIKDADVRAIRPQLITRMNLEAAVTTEMLDFACEINPQDVCLVPEHRAEVTTEGGLDVVKNFTQVQAAIKQLQTQGIRVSLFIDADDAQIQAAAEAGATVIEIHTGRYADAVNQVEQQAELLRVKQGVLMGVQRGLRVNAGHGLHYTNVQAIAAIPDISELNIGHAIVAHAVFVGWEKAVRDMKAIMVNARLSGGLNLGFSGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GY40</accession>
    <name>A0A2S9GY40_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2675</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92620">
        <property type="protein sequence ID" value="PRC92620"/>
        <property type="gene ID" value="S2091_2675"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="46"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="64" mass="7202" checksum="DA996898ABB7827E" modified="2018-07-18" version="1">MSELKTISWLVWLLVSIWLVFHFIGFGGLCAMFPEGKRAWHLPAQLASLAIFAAAILCNPWSLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYJ0</accession>
    <name>A0A2S9GYJ0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2519</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92789">
        <property type="protein sequence ID" value="PRC92789"/>
        <property type="gene ID" value="S2091_2519"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010124">
        <property type="term" value="P:phenylacetate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012347">
        <property type="entry name" value="Ferritin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007814">
        <property type="entry name" value="PaaA_PaaC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05138">
        <property type="entry name" value="PaaA_PaaC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="SSF47240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="246" mass="28674" checksum="C046377BAF41E09B" modified="2018-07-18" version="1">MEMAIERVTSVIDEHAVKTPEDFRQMPDEYQQLATRLMLIHTEGELTGADDYIQIFYNLAPNAFEKMICCERAAEEIQHYMLSAEVLEGIGVDTSFMLQQNFLERTNYSNEFVRGVKTWMERGIFSFIGEAVVLEHLLEFQQSSYKPFADIFAKQIIKDEHVHVAHGYRIIKDACETGSGLRDAQAALDRFWPHLMELFGHPLSERSRLYVKWGLRKTTNGELRERFITKTRPRLESLNLVMPENY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYQ9</accession>
    <name>A0A2S9GYQ9_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Type II secretion system protein K</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">S2091_2279</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 11">Cell inner membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the GSP K family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92862">
        <property type="protein sequence ID" value="PRC92862"/>
        <property type="gene ID" value="S2091_2279"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.40.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005628">
        <property type="entry name" value="GspK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038072">
        <property type="entry name" value="GspK_central_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38831">
        <property type="entry name" value="PTHR38831"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03934">
        <property type="entry name" value="T2SSK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002786">
        <property type="entry name" value="XcpX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158544">
        <property type="entry name" value="SSF158544"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="5 11" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 11" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007246"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR002786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PRC92862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="324" mass="34748" checksum="BC1F9CDC1AFE0F0C" modified="2018-07-18" version="1">MRRSLVTLPSAQRGVAIVTALLLAALAITLVMSLFGQQNVQVRSIENQRFQLQKQWVMRGALDWARLILREDARVNRVDYLGEPWSVPLESTRLDQYVDNGRGSEDDTDATLSGYVIDAESRLNLTNLAVAGVVDPATLLAFGSLLSGQGMDPGLATATANMVASTQAKATQFNSDGSVGAAAVSAKILALTQVDDLLAIPGFTPATVAKLRELVVFLPVATPININTASAQVISARIAGISLSDAQQIVTARNQAYYKDLTDLAARWTNSKVPIPAAGVVNTQTNYFIVHGHVQLDRSALDVDALIERTPISGATRVVWVREN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYV7</accession>
    <name>A0A2S9GYV7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Alpha/beta hydrolase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_2324</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S33 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92907">
        <property type="protein sequence ID" value="PRC92907"/>
        <property type="gene ID" value="S2091_2324"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022742">
        <property type="entry name" value="Hydrolase_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002410">
        <property type="entry name" value="Peptidase_S33"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12146">
        <property type="entry name" value="Hydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00793">
        <property type="entry name" value="PROAMNOPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015698694" evidence="2">
        <location>
            <begin position="21"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="domain" description="Hydrolase_4" evidence="3">
        <location>
            <begin position="101"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC92907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="370" mass="42020" checksum="489DF4B8D3E66931" modified="2018-07-18" version="1">MKSILIICLIYVLMCSHADAQVCPDTATYKQARAVIQDMDRILAPTGIQEAYKTKIGGIDQWLNVRGQDKENPIILFIHGGPAAPLTPEIWQFQRPIEEYFTVVNWDQRGAGKTFGEVDPDSISDSIHIANYVDDAIEVAEHIRSKYHKNKIILMAHSWGTIIGLNAALKRPDLFYSYVGIGQVINTRDNERISFDYALEQAKAHKNTVAINELESIAPYPGDQPITRDRIITARKWAQFYGGLSAYRENSDYYFKAPLLSPDYDDSDRCAIDKGNMYTLGRILPEFLNVDLTGIHSFPIPVVMFMGRHDYTTPTMPTAIWLKKVKAPYKEGVWFERSSHMIPWEEPGKMLVSLLKYVRPLAADSTKRSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZ08</accession>
    <name>A0A2S9GZ08_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Flagellar transcriptional regulator FlhD</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">flhD</name>
        <name evidence="5" type="ORF">S2091_2379</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 4">Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer; disulfide-linked. Forms a heterohexamer composed of two FlhC and four FlhD subunits. Each FlhC binds a FlhD dimer, forming a heterotrimer, and a hexamer assembles by dimerization of two heterotrimers.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="4">The C-terminal region contains a putative helix-turn-helix (HTH) motif, suggesting that this region may bind DNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the FlhD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92962">
        <property type="protein sequence ID" value="PRC92962"/>
        <property type="gene ID" value="S2091_2379"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044780">
        <property type="term" value="P:bacterial-type flagellum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045893">
        <property type="term" value="P:positive regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902208">
        <property type="term" value="P:regulation of bacterial-type flagellum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.4000.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00725">
        <property type="entry name" value="FlhD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023559">
        <property type="entry name" value="Flagellar_FlhD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036194">
        <property type="entry name" value="FlhD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05247">
        <property type="entry name" value="FlhD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63592">
        <property type="entry name" value="SSF63592"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0010">Activator</keyword>
    <keyword evidence="4" id="KW-1005">Bacterial flagellum biogenesis</keyword>
    <keyword evidence="5" id="KW-0966">Cell projection</keyword>
    <keyword evidence="5" id="KW-0969">Cilium</keyword>
    <keyword evidence="1 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0282">Flagellum</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00025431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC92962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="105" mass="11691" checksum="2789D9CA5980DF3E" modified="2018-07-18" version="1">MTPNDMMAEIRDSNLSYLMLAQQMIRSDKATAIFRLGIGKEIADLIEGLNNAQILKLAGSNMMLARFRFEDSSILSMLTNYNKDRALAQSHAAILMAGQSVEEIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZ15</accession>
    <name>A0A2S9GZ15_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Metallo-beta-lactamase superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2364</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92947">
        <property type="protein sequence ID" value="PRC92947"/>
        <property type="gene ID" value="S2091_2364"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015543956" evidence="1">
        <location>
            <begin position="32"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="domain" description="Lactamase_B" evidence="2">
        <location>
            <begin position="94"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="316" mass="34674" checksum="C01C60134EDBC69B" modified="2018-07-18" version="1">MKTQFSLNWTCGLAMMLTLASLSGCGITSHAVVPSTLGKVSSSTEMESMLAQPGPVELTAINSVNWTVPLSGMVNLNNPIAQQAQLKDRDEPIHVYVHVLKHPKYGNFLVDTGVAQQLIDDPDKAGVSWIVAKVMHLEKMKLQTSTDDVLRTMPGQLSGVFFTHLHIDHISGMPAIPNDVPLYIGKSETTGKNWINMFVFSSTNNLLAHKQNLQEWNFEPDPQHQFDAVVDVFGDGSVFAISVPGHTPGSVAYLVRSTKGPVLLTGDTSHTRWGWDHGVEPGDFTNEQAENLVNLMRLKALVARHPEIVVRLGHQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZ21</accession>
    <name>A0A2S9GZ21_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Chemotaxis protein methyltransferase</fullName>
            <ecNumber evidence="5">2.1.1.80</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_2388</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>L-glutamyl-[protein] + S-adenosyl-L-methionine = [protein]-L-glutamate 5-O-methyl ester + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:24452"/>
            <dbReference type="Rhea" id="RHEA-COMP:10208"/>
            <dbReference type="Rhea" id="RHEA-COMP:10311"/>
            <dbReference type="ChEBI" id="CHEBI:29973"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:82795"/>
            <dbReference type="EC" id="2.1.1.80"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.80" evidence="5"/>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92971">
        <property type="protein sequence ID" value="PRC92971"/>
        <property type="gene ID" value="S2091_2388"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008983">
        <property type="term" value="F:protein-glutamate O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.155.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026024">
        <property type="entry name" value="Chemotaxis_MeTrfase_CheR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022642">
        <property type="entry name" value="CheR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000780">
        <property type="entry name" value="CheR_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022641">
        <property type="entry name" value="CheR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036804">
        <property type="entry name" value="CheR_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01739">
        <property type="entry name" value="CheR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03705">
        <property type="entry name" value="CheR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000410">
        <property type="entry name" value="CheR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00996">
        <property type="entry name" value="CHERMTFRASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00138">
        <property type="entry name" value="MeTrc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50123">
        <property type="entry name" value="CHER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 5 8" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="CheR-type methyltransferase" evidence="7">
        <location>
            <begin position="11"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="6">
        <location>
            <begin position="208"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="6">
        <location>
            <begin position="226"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="88"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="90"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="94"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="125"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="150"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR000410"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000410-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC92971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="281" mass="32160" checksum="5BA3D286A5D64EBB" modified="2018-07-18" version="1">MLKVGSNGKSESVKEFDFTHKDFERVRGLIYQRAGISLTESKQEMVYSRLARRLRASHMSSFGEYLDALERGHDPAEWEAFTNALTTNLTSFFREEHHFPLLAEYAASLKEPITVWCSASSTGEEPYSIAITLCEAFKSLNPPATVIATDIDTNVLSTASKGVYNIDRLDKMSNERVKKYFLRGKGEQDGLVRVRPELRNMIEFKQLNLLSDSWPISGAFDVIFCRNVMIYFDKPTQKKILHRFAPLLKPHGLLFVGHSENFSYLTDLFHLRGKTVYELSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZA8</accession>
    <name>A0A2S9GZA8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2150</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93064">
        <property type="protein sequence ID" value="PRC93064"/>
        <property type="gene ID" value="S2091_2150"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="75" mass="8391" checksum="74F91ECDB8B751B1" modified="2018-07-18" version="1">MDKTQATAMKRYTKSAIQAEKHLRAAANALAEMHHASKPAGIPIRGLDDTRLTLQENCREYANFLNSVFTKKDNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZC8</accession>
    <name>A0A2S9GZC8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GGDEF: diguanylate cyclase (GGDEF) domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2146</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93060">
        <property type="protein sequence ID" value="PRC93060"/>
        <property type="gene ID" value="S2091_2146"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GGDEF" evidence="1">
        <location>
            <begin position="205"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="342" mass="37530" checksum="CFBF6A85DAF12834" modified="2018-07-18" version="1">MKTPVGTSAVNQEANTGVASFAISPQEDRILRIERIAIRLFGVANCIVSFGQVSARFGKGERSMAALEAAFCDSLSFPHDPVIVNDARLDPKTATNPWVVGAPYIRFYASQPIVDNNAVVGAIFLIDYVARQYQEEDTFLLNDLSGLVEQELQFDSMQAAHDDMVRQNRSLRRDSMIDPMFGTWNRGAIVRSLEIEVIRCRAAAKPMSLAMVSVDNYADLKNEFGLHASEAILIKMVSRMRSCIRPFDALGRYGTEEFLVVLPGASHVVIQAITERIRSTVLAHPEVINDKTRDVTVCVGTVSTDVFTTASPDELMSQVEQALHSAKKVGNNSVIHAVPVGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZH1</accession>
    <name>A0A2S9GZH1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2189</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93103">
        <property type="protein sequence ID" value="PRC93103"/>
        <property type="gene ID" value="S2091_2189"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="121" mass="13010" checksum="2D1E84583B59B7B9" modified="2018-07-18" version="1">MAIKGISKSIEEVNTGSAAAFHRIEHYSVDMRSKYVSLIVRGYVTEAACDNGKLHIMETTTTIAQAPALTDNVLEFLYKTITAVAPEAIPSQSQPAMPVPVAINAFAGAELVYEVVAKVKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZT4</accession>
    <name>A0A2S9GZT4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1965</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93227">
        <property type="protein sequence ID" value="PRC93227"/>
        <property type="gene ID" value="S2091_1965"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015519043" evidence="1">
        <location>
            <begin position="28"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="171" mass="19731" checksum="E33C4AACCEC2412B" modified="2018-07-18" version="1">MKINIKNHKYLAFFCLITFGAFQSVSANPDCMSQIHNYSNQTWTFWFERTGDAGPLDYDVKQKQYIDRRLMRIPCTKKTPCTLEGHTVVDISYLLWEDKKKKSDLVPVKAVFVDRNGGSKYWESSLTGFFQGVNICHKFNTPDFNPHDPIAVNSPANGDFSIWTNDFSTKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZT7</accession>
    <name>A0A2S9GZT7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1982</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93244">
        <property type="protein sequence ID" value="PRC93244"/>
        <property type="gene ID" value="S2091_1982"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015634382" evidence="2">
        <location>
            <begin position="31"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="239"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="261" mass="28934" checksum="30354820FD64B92C" modified="2018-07-18" version="1">MNLHIKTSHYFYLLTACAALISFAPQLSYADGLADMKSALTRGQGQTPVKAIFDVKIKNREGEGKELEETNGLANVMVEDNAHGLQLQFGRELMSKLDLEQRTQEHDSKAKTPTVTAAKELSSTEAQHMLYAASSISRSLEKAVFKSERAESWNGKPARLLSFEYSQDKMSEKDRKYVKKFNGTVDIWIAQDGTPLASRKLMTVSGSAMIVISFESSNEESEVYAMVGDRLIVTRKENKTSQSAFGEKGESSTVKTLQVQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZU0</accession>
    <name>A0A2S9GZU0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cation/multidrug efflux pump</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1990</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93252">
        <property type="protein sequence ID" value="PRC93252"/>
        <property type="gene ID" value="S2091_1990"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2090.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027463">
        <property type="entry name" value="AcrB_DN_DC_subdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001036">
        <property type="entry name" value="Acrflvin-R"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32063">
        <property type="entry name" value="PTHR32063"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00873">
        <property type="entry name" value="ACR_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00702">
        <property type="entry name" value="ACRIFLAVINRP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82714">
        <property type="entry name" value="SSF82714"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="365"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="436"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="463"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="534"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="885"/>
            <end position="908"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="915"/>
            <end position="935"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="941"/>
            <end position="964"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="985"/>
            <end position="1009"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1021"/>
            <end position="1044"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="1059" mass="115101" checksum="E62C683B5BB6D919" modified="2018-07-18" version="1">MLWIVRVALRRPLTFIVLALLIFILGPLVYLSMRTDIFPDIKIPVVSVVWTYNGLPPNDISDRIITYYERQMTTTVNDIEHIESQSLSGVGIVKVFFQPDVNINAAVSQVTALSQTVLKRLPPGITPPLILSYNASSVPILQLALSSNTLLDNQLFDISNNFIRPQLAEVEGAAVPSPYGGKNRQIQVDLNLEALRSKGLAPEDVTSAIDKQNLILPAGTEKIGVFEYNILLNASPKVLDELNDLPIKSANKSTNKSTIFLRDVAHVRDGFSPQYNMVRVDGRHSVLTTIQKNGTASTLSIIDHVKKLLPKIEAGAPLGLIVGLVGDQSVFVRSAVSEVIREGVIAATLTGLMILLFLGSWRSTIIITISIPLAILSAIIGLSIVGQTINIMTLGGLALAVGILVDDATVTIENINWHLEQGKYVNEAIMDGAGQIVVPAFVSLLSICIVFIPMFFMRGVAQYLFVPLAEAVIFAMIASFILSRTLVPTMANYLLRPQGRPEHGVSVPTRNLLILFQRAFEKLFIKLRQGYKELLMVALSFRLIFILGFLGFVFVSFLLLPWLGQNFFPTVDAGQIKLHIRAQTGTRLEETTRLCDLIEQEIKNQIPSSEITNIVDNIGLPISGINLSYSNSSPIGPGDADILISLNKGHRPTADYVRQLREKLSDDFPGVAFAFLPADIVSQILNFGLPAPIDIQIIGFHRSANQEYATKLMNRVKMIPGLVDLRIQQAFNQPEFHVNVDRARALDVGLTQRDVATSLLVSLSGSLQTAPNFWVDPKNNVSYPLVVQVPQYQMDTLNHLQNIPITTNAGLQILGGLATITRGQGAAVVSHYDVQPTLDIFGSPQDRDLGAVANDIKRILAETATEVPKGSEVVLRGQVQAMDSAYSGLLFGLVGAIVLIYMLIVVNFQSWLDPFVIITALPAALAGIVWMLFITHTSLSVPALIGSIMCMGVATANSILVVSFAREQHNNGVSGMVAALESGFLRFRPVLMTALAMIIGMTPMALGLGEGGEQNAPLGRAVIGGLIFATFATLFFVPVVFSLVHSSEIIPVEPATESS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZV4</accession>
    <name>A0A2S9GZV4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphoesterase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1985</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93247">
        <property type="protein sequence ID" value="PRC93247"/>
        <property type="gene ID" value="S2091_1985"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007312">
        <property type="entry name" value="Phosphoesterase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31956">
        <property type="entry name" value="PTHR31956"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04185">
        <property type="entry name" value="Phosphoesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015479831" evidence="1">
        <location>
            <begin position="24"/>
            <end position="619"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="619" mass="64304" checksum="64AC4BEAAEC46D0B" modified="2018-07-18" version="1">MNLQSISVKQPLMMTALALSVSAAVITGCSSGSSPAASAPATPVVAAATAATPIQHVVVIFQENVSFDHYFGTYPTAANPAGEPGFTAASGTPVANTLATPLDVTNKFAALTSLNLMTKNPTTLNAKNGTNAINPFRLDRSQVVNSDQDHDYQAEQMAFNAGAMDLFPLSLGAANSGTTAPLNTNGLTMGYFDGNTVTAFWNYAQNYAMSDNSFGTTFGPSAPGAINLISGQTNGVIATNLSTAQVGNYSAGGGYYGELSADGNGGINLSGDAQPLGDACMTRDAAQLGGKNIGDLLNAGKVSWGFFQGGFDLSITNTNGTTGCKRSTTSGVTGVTKLDYIPHHQPFQYYASTQNLTHARPTSIAAIGNTLVPGTTTVDPANHQYDIHDFFDAVSAGNYPAVNFLKAPGYQDGHTGYSDPLDEQSFVTQVVNFLQQQPGWANTLVIIAYDDSDGWYDHQASPILNPSMNTTAAAQFTSNGLTAPGVADMLNGPGACTSNGAGSLQGTPTKLLGATGTAVAQGRCGYGPRLPMILISPYAKKNYVDHTLTDQTSILRFIEDNWLASQRIAGSYDAIAGTLNNMLNLTGTPSTSVLILDPLTGLPQECPTCKKAAVATIVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H007</accession>
    <name>A0A2S9H007_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2021</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93283">
        <property type="protein sequence ID" value="PRC93283"/>
        <property type="gene ID" value="S2091_2021"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010985">
        <property type="entry name" value="Ribbon_hlx_hlx"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47598">
        <property type="entry name" value="SSF47598"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="94" mass="10292" checksum="F468696FD30101C5" modified="2018-07-18" version="1">MSTTSLKLPDNLKQRAVAAAQLQGVSTHAFMINAIEQAAIAAECRANFIAEAHAARKQMLEVDQGYDADEVHAYIQERIAGKKIAQPKARSWRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H032</accession>
    <name>A0A2S9H032_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2046</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93308">
        <property type="protein sequence ID" value="PRC93308"/>
        <property type="gene ID" value="S2091_2046"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="35" mass="3868" checksum="600CD7D43CA63773" modified="2018-07-18" version="1">MQYVLVLAVDKREDSAVYASAKLRLELKIKSGNAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0C9</accession>
    <name>A0A2S9H0C9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="8">3-dehydroquinate synthetase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_1814</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93427">
        <property type="protein sequence ID" value="PRC93427"/>
        <property type="gene ID" value="S2091_1814"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016838">
        <property type="term" value="F:carbon-oxygen lyase activity, acting on phosphates"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030963">
        <property type="entry name" value="DHQ_synth_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030960">
        <property type="entry name" value="DHQS/DOIS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01761">
        <property type="entry name" value="DHQ_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001455">
        <property type="entry name" value="DHQ_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0170">Cobalt</keyword>
    <keyword evidence="5" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0520">NAD</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DHQ_synthase" evidence="7">
        <location>
            <begin position="94"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC93427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="399" mass="43601" checksum="4BE5DD828F506AFA" modified="2018-07-18" version="1">MHSATLSSPTVISEWQQQRFQINYAFPVISTRNIFSPTNLHLKKVLCLREKNTRHRVAIFIDSGVLNASPQLIAQIHAYAAMHADVIEIVGDIVLVPGGESCKNDDTTIPTLLEALSTRAIDRHSYTIAIGGGAVLDAVGYAAAIFHRGVRHIRLPSTVLAQADSGVGVKNAVNWEGKKNLLGCFAPPWAVINDGSLIDALPEREKIAGMAEAVKVGLIRDRDFFEWLENNVALLAAFDSTALDSLISHSAMLHMRQIAHGGDPFEMGSARPLDFGHWAAHKMERLSKHALSHGEAVAIGIALDTRYSYLRGLLTVEEDQRIYNLLKQLGFTLWHPCLLERQANGDYEVLRGLTDFQEHLGGELSITLLAAIGAGIEVSTMDHALIAQAITDLQDLACN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0K7</accession>
    <name>A0A2S9H0K7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Myosin-crossreactive antigen</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1898</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93511">
        <property type="protein sequence ID" value="PRC93511"/>
        <property type="gene ID" value="S2091_1898"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050151">
        <property type="term" value="F:oleate hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010354">
        <property type="entry name" value="Oleate_hydratase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37417">
        <property type="entry name" value="PTHR37417"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06100">
        <property type="entry name" value="MCRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="523" mass="58848" checksum="F9717DF9370BEB0B" modified="2018-07-18" version="1">MKKISKAYLLGGGIGSLATAAFMIRDGNVAGEQIHILEAALVMGGSLDGAGNPEQGYSLRGGRMFTTDNYECTWDLYKSIPSLNFKDKTVFDETVDFNEKHIANSKARLVDSRRAKVPVSSMGFSMQDRVELLKLANTDEDTLGASCITDWLSPEFFNTEFWAMWATTFAFQPWHSAVEFKRYLHRFMLEFSRIETLGGVKRTIYNQYDSLVLPLKHWLEEHGVCFVTGCTVTDLDHKIEDDQFVVTAIHCLRNGQQEQIQVNDEDLVFFQNGTMTDASSLGSMQHAPAKLTKADSTSWALWEKLAKSRSDFGNPSAFNSSIAESVWESFTVTLKNPAFFNKMIQFSGNEPGTGGLVTFKDSNWFMSTVLANQPHFANQPVDVQVFWGYALFPDRVGNYVAKPMSECNGEEILKELCGHLRFDLATVESANCIPCRMPYITSMFMPRLLSDRPLPVPPASKNLAFVSQFVEIADDVVFTVEYSVRAAQMAVYQLLEIDRKVRPIMRHDKSLQTQLDVLVKAFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0T8</accession>
    <name>A0A2S9H0T8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">WbqC-like protein family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1561</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93560">
        <property type="protein sequence ID" value="PRC93560"/>
        <property type="gene ID" value="S2091_1561"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014985">
        <property type="entry name" value="WbqC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08889">
        <property type="entry name" value="WbqC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="232" mass="27579" checksum="1957943A712C012D" modified="2018-07-18" version="1">MKKIAILQSNYIPWKGYFDMISAVDEFILYDDMQYTRRDWRNRNQIKTPQGLLWITVPVLVKGKYHQKIRDTEINDNDWAANHWKALVQNYRRAPHFEEIALWLEPIYLTKTYTHISQLNRNLIEAICNYLHITTRITNSWDYNLLDDGKTERLADLCKQAGGSEYISGPSAKDYVEERVFTDMEIQLSWFNYNDYPVYPQLWGEFTHGVTILDLLFNCGKDAHKYMRHVSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0Y5</accession>
    <name>A0A2S9H0Y5_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Protein translocase subunit SecD</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">secD</name>
        <name evidence="11" type="ORF">S2091_1642</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the SecD/SecF family. SecD subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93641">
        <property type="protein sequence ID" value="PRC93641"/>
        <property type="gene ID" value="S2091_1642"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015450">
        <property type="term" value="F:protein-transporting ATPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0065002">
        <property type="term" value="P:intracellular protein transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006605">
        <property type="term" value="P:protein targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043952">
        <property type="term" value="P:protein transport by the Sec complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01463_B">
        <property type="entry name" value="SecD_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005791">
        <property type="entry name" value="SecD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027398">
        <property type="entry name" value="SecD-TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022813">
        <property type="entry name" value="SecD/SecF_arch_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022645">
        <property type="entry name" value="SecD/SecF_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022646">
        <property type="entry name" value="SecD/SecF_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30081">
        <property type="entry name" value="PTHR30081"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07549">
        <property type="entry name" value="Sec_GG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13721">
        <property type="entry name" value="SecD-TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02355">
        <property type="entry name" value="SecD_SecF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00916">
        <property type="entry name" value="2A0604s01"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01129">
        <property type="entry name" value="secD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0811">Translocation</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="454"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="483"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="553"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="579"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="domain" description="SecD-TM1" evidence="10">
        <location>
            <begin position="1"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF13721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC93641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="619" mass="66526" checksum="9A6939CE30546E3B" modified="2018-07-18" version="1">MNRYPAWKYVLIVLALAFGILYTVPNFYSPSPALQVNSAKATVKVDSTMQARVEDALKAANLANTGIFFNVNGTQGVVRARFVDPDAQFKAKEALEKALNPDQTDPAYSVTFNSMSSAPSWLQSIHALPMFLGLDLRGGVHFLMQVDTNGVLTKRLQGMQASIRSSLRDKDIRHSGIERNAEQIIIKFTDADTRTKAKNLILDQQRDADVIESGAGTDLTLTVSLKPLALQQAKADGVKQNIATLAKRINELGTQEPIIQQQGIDRIVVELPGVVDVARAKDIIGRTATLEVRMRDETILEGTDGTATVPYGSELFKAGKNVPVILLKDPVLTGESISGASASFDQHQQPAVSIDLNGDGGRKMREATRGKIGKRMAIVLFEKGKGEVLTVPTIQAELGSSFQITGMGSTEAASDLALLLRAGALAAPMAIIEESVIGPQLGADNIKQGFDSTLYGFIAISIFMICYYMLFGGFSVLALSFNLLLLVAILSLMQIALTLPGMAAIALALGMAIDSNVLINERIREELRAGNSPQAAISAGFDRAWATILDSNVTTLIVGLALLAFGSGSIRGFAVVHCLGILTSMFSSVFVSRGVVNLWYGRKRKLTKLSIGQIWKPAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H137</accession>
    <name>A0A2S9H137_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Acetyl-CoA dehydrogenase C-terminal like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">S2091_1577</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93576">
        <property type="protein sequence ID" value="PRC93576"/>
        <property type="gene ID" value="S2091_1577"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016627">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025878">
        <property type="entry name" value="Acyl-CoA_dh-like_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020953">
        <property type="entry name" value="Acyl-CoA_DH_N_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12806">
        <property type="entry name" value="Acyl-CoA_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12418">
        <property type="entry name" value="AcylCoA_DH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="SSF47203"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="SSF56645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AcylCoA_DH_N" evidence="8">
        <location>
            <begin position="3"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_N" evidence="7">
        <location>
            <begin position="82"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_M" evidence="6">
        <location>
            <begin position="165"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_1" evidence="5">
        <location>
            <begin position="284"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_C" evidence="9">
        <location>
            <begin position="471"/>
            <end position="592"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF12806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC93576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="596" mass="65331" checksum="D3EE77D5CA17F29F" modified="2018-07-18" version="1">MGQYIAPMRDMQFVLHELLHVEDELKQLPKHAEIDADIINQVLEEGGKFTSQVLFPLNHSGDREGCHYNKEDQSVTTPKGFKAAYEQYVAAGWPALSCDPEFGGQGLPLVINNSFYEMMNSSNQAWTMYPGLSHGAYECIHHHGTPEQQALYLPKLISGEWTGTMCLTESHCGTDLGMLRSKAEPQADGSYKITGNKIFISAGEHDMAKNIVHLVLARLPGAPEGSKGISLFITPKYLPNADGTVGARNPITCGAIEEKMGIHGNSTCQMNLDGATGWLIGGPNKGLQAMFVFMNAARLGVGMQGLGITEIAYQNALVYAKDRIQMRSLSGVKAPEKAADPIIVHPDVRRMLLTAKAYAEGARAFCSYVALQLDKELNHPDEEVRKDCADQVALLTPIIKAFITDNAWISTSECLQVYGGHGFIAEWGMEQYVRDARINMIYEGTNTIQSLDLLGRKILMDNGAKLRKFGAQVQAFVEANGTDEAMSEFITPLADLGDKVTKLTMEIGMKAFQNPDEVGAAAVPYLRVVGHMVYAYFFAQMAKIALAKEDSGDTFYKAKLATARFYFARLLPETATLIRQARSGSANLMALDADLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H167</accession>
    <name>A0A2S9H167_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1709</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FrmR/RcnR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93708">
        <property type="protein sequence ID" value="PRC93708"/>
        <property type="gene ID" value="S2091_1709"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003735">
        <property type="entry name" value="Metal_Tscrpt_repr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038390">
        <property type="entry name" value="Metal_Tscrpt_repr_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33677">
        <property type="entry name" value="PTHR33677"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02583">
        <property type="entry name" value="Trns_repr_metal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005260"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="89" mass="10047" checksum="3559A0071E30BD0E" modified="2018-07-18" version="1">MSTHTSHPDIIKRLKRAAGHLKSTIDMLESDRECLEIVQQLQAVEKAIANAKKVLVHDHIDHCLENAVKKGSRNSGEIVSEFKEITKYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H178</accession>
    <name>A0A2S9H178_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ABC-type branched-chain amino acid transport systems ATPase component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_1718</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93717">
        <property type="protein sequence ID" value="PRC93717"/>
        <property type="gene ID" value="S2091_1718"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032823">
        <property type="entry name" value="BCA_ABC_TP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12399">
        <property type="entry name" value="BCA_ABC_TP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-1278">Translocase</keyword>
    <feature type="domain" description="ABC transporter" evidence="7">
        <location>
            <begin position="5"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="37"/>
            <end position="44"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC93717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="254" mass="27791" checksum="6F86FF0732663FDE" modified="2018-07-18" version="1">MKPILQAINVSKHYGKFTAVNDITLDILPGTIHSVIGPNGAGKTTLFHTLTGTVPISAGSILLNGEEVAHLPAYKRVSKGLARSFQVTNLFPNLSVTENLRLAAQGRYFAQALNPWRRVESLNLAGDIASQLIEQLQLQHFSQRAAGELSHGQQRRLEVGMAMAGQPKVIFLDEPTSGMGVDDIAEMKQFIHGLRVQYTVLLIEHNMDIVMDISDQITVMQQGQILAAGKPEQIRNNELVRRAYLGSMITGGKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H191</accession>
    <name>A0A2S9H191_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1752</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93751">
        <property type="protein sequence ID" value="PRC93751"/>
        <property type="gene ID" value="S2091_1752"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="69" mass="7799" checksum="2C840DD06925A0D7" modified="2018-07-18" version="1">MIEFLLLILMVGDTGAVLKLVLVLKLVLKLVLKLVLKLVLKLVLKLILKLVLKLILKLSLTLLLTYPHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1G7</accession>
    <name>A0A2S9H1G7_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 10">Phosphoenolpyruvate carboxylase</fullName>
            <shortName evidence="10">PEPC</shortName>
            <shortName evidence="10">PEPCase</shortName>
            <ecNumber evidence="5 10">4.1.1.31</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">ppc</name>
        <name evidence="14" type="ORF">S2091_1417</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 10">Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>oxaloacetate + phosphate = hydrogencarbonate + phosphoenolpyruvate</text>
            <dbReference type="Rhea" id="RHEA:28370"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="EC" id="4.1.1.31"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="10">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the PEPCase type 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.31" evidence="5 10"/>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93808">
        <property type="protein sequence ID" value="PRC93808"/>
        <property type="gene ID" value="S2091_1417"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008964">
        <property type="term" value="F:phosphoenolpyruvate carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015977">
        <property type="term" value="P:carbon fixation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006107">
        <property type="term" value="P:oxaloacetate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00595">
        <property type="entry name" value="PEPcase_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021135">
        <property type="entry name" value="PEP_COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022805">
        <property type="entry name" value="PEP_COase_bac/pln-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018129">
        <property type="entry name" value="PEP_COase_Lys_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033129">
        <property type="entry name" value="PEPCASE_His_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_Kinase-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30523">
        <property type="entry name" value="PTHR30523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00311">
        <property type="entry name" value="PEPcase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00150">
        <property type="entry name" value="PEPCARBXLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="SSF51621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00781">
        <property type="entry name" value="PEPCASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00393">
        <property type="entry name" value="PEPCASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0120">Carbon dioxide fixation</keyword>
    <keyword evidence="8 10" id="KW-0456">Lyase</keyword>
    <keyword evidence="7 10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="14" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="active site" evidence="10 11">
        <location>
            <position position="162"/>
        </location>
    </feature>
    <feature type="active site" evidence="10 12">
        <location>
            <position position="595"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00003670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00595"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="PRC93808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="933" mass="103561" checksum="434024D35B8DCF3F" modified="2018-07-18" version="1">MNAQAIPASTPPNASALLNNDDKDQQLRDDIRHLGRILGDTVRSQHGDEIFNIIEIVRQSSIRFGRDEDEVSKQALEAMLDGLSNDEMTKVIRAFSYFSHLSNIAEDQHHIRRTRAHLVAGSPPKQGSLAYTISTLMERGYSTAQLVEFFQTAIVSPVLTAHPTEVQRKSILNCQMVIGRLLNERDRMQLTPEETAANEEALNRAVLTLWQTRMLRNSKLSVLDEVENGLTFYDYTLLRELPNLYAGLEDLLSQQSPSKEPTELASFLKMGSWIGGDRDGNPFVTATVLEQTLTMQCTRALRFYLDELHALGSQLSVAQLLVGASDQLLALADSSPDQSVHRSDEPYRRAISGMYARLSATYHELLGGEPVIHPSGQARAYQNVEQLSADLAIVHNSLLLNGSAALTRGRLRHLRRAVDVFGFSLAPIDLRQNSDVHERVVAELFAAANPACRYLEQDEAGRIALLLAEISTPRPLSSPYLVYSEETQSELAIYRAARTAQDRYGKAAVPNCIISKTDSVSDLLELAVLLKEAGLLHPQEARLDVNIIPLFETIADLRNSAPVMKHLLSLPEYARLLDSRDLAQEVMLGYSDSNKDGGFLTSGWELYKAELALIDVFAEKKIRLRLFHGRGGSVGRGGGPSYQAILAQPAGAVQGQIRLTEQGEVITAKYANPEVGRRNLEVLAAATLEASLLAETEPAPRPEFLTCMNALSDHAFAAYRNLVYETEGFEQYFWESTVISEIAGLNIGSRPASRKKTTAIDDLRAIPWVFSWSQCRLMLPGWYGFGSAVRAYLEAHPDTGLALLQEMYRDWPFFTTLLSNMEMVLAKSDLSIASRYAGLVKEEQLRETIFTRICKGHVATIAALKSISGQSELLAANPLLKRSIRNRFPYMAPLNHVQVELLKRFRNGDQDERVRRGIHLSINGIAAGLRNSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1J5</accession>
    <name>A0A2S9H1J5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Superfamily II DNA and RNA helicase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">S2091_1422</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the DEAD box helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93813">
        <property type="protein sequence ID" value="PRC93813"/>
        <property type="gene ID" value="S2091_1422"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 6 10" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Q_MOTIF" evidence="9">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="7">
        <location>
            <begin position="32"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="8">
        <location>
            <begin position="234"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="5">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC93813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="416" mass="45883" checksum="F6B72DA839A9FF49" modified="2018-07-18" version="1">MPFTTLNLHPALLRAITQRGYAEPTPIQLAAIPAILQGGDVVASAQTGSGKTAAFGLPLLQQWNLQRTSTPRKVSTLILVPTRELATQVGDTLRSLAQYLPKPIKLAIVFGGISINPQMLHLRGGADIVIATPGRLLDLIKHNAVSLSFVQTLVLDEADRLLELGFADELTQLLALLPPQRQNILFSATFPEQLSQLTEDFLRTPTRIEVEHTAINKPDILQRSIVVDTDKRTQLLRHLIETMRWERVLVFAASRYSAELIAVKLRKARIAAEPFHGELSQGKRTQVLADFKACRVKVVVATDVAARGIDIAQLPVVINYDLPRSSDDYTHRIGRTGRAGLSGLAINFISTGNEAHFRLIENRQNIKLERERISGFEPLLTDVSISTEDKGDGGIKGKRPNKKDKLRALALAQVKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1L4</accession>
    <name>A0A2S9H1L4_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">LPS-assembly protein LptD</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">lptD</name>
        <name evidence="4" type="ORF">S2091_1365</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Component of the lipopolysaccharide transport and assembly complex. Interacts with LptE and LptA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the LptD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93756">
        <property type="protein sequence ID" value="PRC93756"/>
        <property type="gene ID" value="S2091_1365"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043165">
        <property type="term" value="P:Gram-negative-bacterium-type cell outer membrane assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015920">
        <property type="term" value="P:lipopolysaccharide transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010033">
        <property type="term" value="P:response to organic substance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01411">
        <property type="entry name" value="LPS_assembly_LptD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020889">
        <property type="entry name" value="LipoPS_assembly_LptD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007543">
        <property type="entry name" value="LptD_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04453">
        <property type="entry name" value="LptD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015789386" description="LPS-assembly protein LptD" evidence="1">
        <location>
            <begin position="37"/>
            <end position="801"/>
        </location>
    </feature>
    <feature type="domain" description="LptD" evidence="3">
        <location>
            <begin position="312"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="47"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01411"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC93756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="801" mass="89652" checksum="13796F81204AEEE0" modified="2018-07-18" version="1" precursor="true">MLHLMRRNPLLSHLSPSMLSKMSLAVLATFSTPLYAGDIATAAATSTDVTDVSSAPVDTEAVAQRPEDSNKITARAEQMTGRPDRILNFDGQVEIVRGPSTLNADTAEYHAIEDLVMAHGNVQMLRNKDCYSGDTFQMQMDTGSGYLTNPVYQLEKNNARGFATRMDFIDKDQSVVEQGVYTTCEGTKPDWYLRSSRLDLDTGRDEGVATNGVVFFKDVPILGSPWMSFPISDARRSGVLPPEFSSTTTGGAELTVPYYFDIAPNRDATIFPNYISKRGEQLGGEFRYLDSTYSGLLHAEITPQDAADNNDTRYSISYLHNQTLLPGLTMSLNYNRASDDNYAIDYSHSITQSSQHLLPQMFTLGYGQSFWNVGLTMLNYQVLQIADVPLTDQIQKPYQIMPQLLAHAGKINDFGGFDWSIDTQYTNFRSSTGEDSERFVVQPQISYPITGTYYFITPKFSYHLSEYRLGETLATSSNSSDPVLSVPTFSLDSGLYFEREANLFGRDLTQTLEPRLFYVNTPYRDQTNVPIFDTGIADINFAQIFTENRFSGQDRVGDANQLTAALITRAIEMDGQERMRFAIAQRLSFSQPLVTDTITPFYSTTIIEGNNSITTTHSSLPSRSDLIFAASGKLTNTLTTDALWQYSQSQQSTAQLTYGFKWQPAPMQVINAEYRFQNISEVDPEGMKQIDVSAQWPLAPRWYGVARANYSIQDRRILDGLIGFEYKQDCWIFRAVAQRYLVPSTVAEITSSSTTSLFFQLELNGLSKIGTNPLQALKRSIPGYQPINQPTTQPGYQQNNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1L6</accession>
    <name>A0A2S9H1L6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="11">HrcV: type III secretion protein, HrcV family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">S2091_1467</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93858">
        <property type="protein sequence ID" value="PRC93858"/>
        <property type="gene ID" value="S2091_1467"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.540">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042194">
        <property type="entry name" value="FHIPEP_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042193">
        <property type="entry name" value="FHIPEP_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042196">
        <property type="entry name" value="FHIPEP_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025505">
        <property type="entry name" value="FHIPEP_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001712">
        <property type="entry name" value="T3SS_FHIPEP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006302">
        <property type="entry name" value="T3SS_HrcV"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30161">
        <property type="entry name" value="PTHR30161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00771">
        <property type="entry name" value="FHIPEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005419">
        <property type="entry name" value="FlhA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00949">
        <property type="entry name" value="TYPE3IMAPROT"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01399">
        <property type="entry name" value="hrcV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00994">
        <property type="entry name" value="FHIPEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="39"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="70"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="110"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="197"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="239"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="271"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="299"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC93858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="689" mass="76170" checksum="CEC32ABA7DC39963" modified="2018-07-18" version="1">MISRFLTNARAHPELIIVMLMVMVIAMLIVPLPTFLVDFLIALNIVIAILLFMGSFYVERILNFSTFPTILLITTLFRLALSISTSRLILTQADAGEIIATFGDYVIGDSLIVGFVIFSIVTIVQFIVITKGSERVAEVAARFSLDGMPGKQMSIDGDLKAGVIDAEGAKERRSVLERESQLYGSFDGAMKFIKGDAIAGIIIILVNLIGGIAVGVTSHHMDMYTALQTYTMLTIGDGLVAQIPALLISISAGFIVTRINGDDANLGRNIMGQLLGMPFAVAITALLAVLVAFLPGFPMVAFLGLAVVLGLFLYIGQRRRQREESGSEIVAGEAEAQSEAAQDSDRSQLGLITDLDKVATETVAFILLVPQAQQQYCIDEQLGQRLRSQFFIDYGVRLPEFLVRGSDTQPKDCVALLINEIRTETLYVCFNKMRIVNMSDEVGQLGIHVEVLTDAAQQDGHWVTPSHREELIKLGFQLRSAQDELYQCLVAVLVKHVPEFFGIQETKKMLDQMETSAPDLLKEVLRNVTVQKISEVLQRLLSERISIRNFKLILESLAQWGGREKDVIALVEHVRGAMARYISHKFSIGNKLRVVMLSTDMEEQVRKGVRQNASGAFLNIEPSVSEEIIDKFALLFQAFPIAQKDLVVLTAVDVRRFVKKLLEARFKDLDVISFGEVASNVEVNVLKVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1T6</accession>
    <name>A0A2S9H1T6_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 10 11">Ribulose-phosphate 3-epimerase</fullName>
            <ecNumber evidence="7 10 11">5.1.3.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">rpe</name>
        <name evidence="15" type="ORF">S2091_1112</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10 11">
            <text>D-ribulose 5-phosphate = D-xylulose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:13677"/>
            <dbReference type="ChEBI" id="CHEBI:57737"/>
            <dbReference type="ChEBI" id="CHEBI:58121"/>
            <dbReference type="EC" id="5.1.3.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10 13">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
        <text evidence="10 13">Binds 1 divalent metal cation per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="10">Carbohydrate degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6 10 11">Belongs to the ribulose-phosphate 3-epimerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.1.3.1" evidence="7 10 11"/>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC93939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93939">
        <property type="protein sequence ID" value="PRC93939"/>
        <property type="gene ID" value="S2091_1112"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00048">
        <property type="reaction ID" value="UER00072"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004750">
        <property type="term" value="F:D-ribulose-phosphate 3-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019323">
        <property type="term" value="P:pentose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006098">
        <property type="term" value="P:pentose-phosphate shunt"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00429">
        <property type="entry name" value="RPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02227">
        <property type="entry name" value="RPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026019">
        <property type="entry name" value="Ribul_P_3_epim"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000056">
        <property type="entry name" value="Ribul_P_3_epim-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11749">
        <property type="entry name" value="PTHR11749"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00834">
        <property type="entry name" value="Ribul_P_3_epim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001461">
        <property type="entry name" value="RPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="SSF51366"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01163">
        <property type="entry name" value="rpe"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01085">
        <property type="entry name" value="RIBUL_P_3_EPIMER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01086">
        <property type="entry name" value="RIBUL_P_3_EPIMER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 11" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="13" id="KW-0170">Cobalt</keyword>
    <keyword evidence="9 10 11" id="KW-0413">Isomerase</keyword>
    <keyword evidence="13" id="KW-0464">Manganese</keyword>
    <keyword evidence="8 10 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="10 14">
        <location>
            <begin position="146"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="10">
        <location>
            <begin position="179"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="10 14">
        <location>
            <begin position="201"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="10 12">
        <location>
            <position position="39"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="10 12">
        <location>
            <position position="179"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10 14">
        <location>
            <position position="12"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10 13">
        <location>
            <position position="37"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10 13">
        <location>
            <position position="39"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10 13 14">
        <location>
            <position position="70"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10 13">
        <location>
            <position position="179"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="181"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00009541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00013188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR001461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR001461-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR001461-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR001461-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="PRC93939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="225" mass="24251" checksum="EFE27A82A288B44E" modified="2018-07-18" version="1">MSTSPTYRIAPSILSADFARLGEEVRNVVAAGADMIHFDVMDNHYVPNLTIGPMICQAIRPHVQVPIDVHLMVKPVDRIIPDFAKAGANIISFHPEATEHLDRTLQLIRDHGCKAGLAINPGTSLNFLEHVMDKLDLILLMSVNPGFGGQSFIPHTLQKIAAVRKLIDASGRDIMLQVDGGVKTDNIAEIARAGADTFVAGSAIFGKPDYPGIIAGMRRELASVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H213</accession>
    <name>A0A2S9H213_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Sec-independent protein translocase protein TatA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">tatA</name>
        <name evidence="10" type="ORF">S2091_1171</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the TatA/E family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC93998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93998">
        <property type="protein sequence ID" value="PRC93998"/>
        <property type="gene ID" value="S2091_1171"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033281">
        <property type="term" value="C:TAT protein transport complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008320">
        <property type="term" value="F:protein transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043953">
        <property type="term" value="P:protein transport by the Tat complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00236">
        <property type="entry name" value="TatA_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003369">
        <property type="entry name" value="TatA/B/E"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006312">
        <property type="entry name" value="TatA/E"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02416">
        <property type="entry name" value="TatA_B_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01411">
        <property type="entry name" value="tatAE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 8" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8" id="KW-0811">Translocation</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="47"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC93998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="71" mass="7733" checksum="3BD57B6D7329D7CC" modified="2018-07-18" version="1">MGSFSIWHWLIVLVIVMLVFGTKKLGNIGEDLGKAVKGFKDGMKTDEEKKAVPPAQVADSSTVDVDAKEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2C4</accession>
    <name>A0A2S9H2C4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">1-aminocyclopropane-1-carboxylate deaminase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_1280</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ACC deaminase/D-cysteine desulfhydrase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94107">
        <property type="protein sequence ID" value="PRC94107"/>
        <property type="gene ID" value="S2091_1280"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008152">
        <property type="term" value="P:metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027278">
        <property type="entry name" value="ACCD_DCysDesulf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="PLP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="Trypto_synt_PLP_dependent"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43780">
        <property type="entry name" value="PTHR43780"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006278">
        <property type="entry name" value="ACCD_DCysDesulf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="SSF53686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PALP" evidence="6">
        <location>
            <begin position="21"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4">
        <location>
            <position position="82"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="5">
        <location>
            <position position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008639"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR006278-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR006278-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC94107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="311" mass="34071" checksum="67E83DA362DCC233" modified="2018-07-18" version="1">MVSMSVFDLSGNGKSPLTSPCQLLGNSTLFGMPVWIKRDDLLHPVVSGNKFRKLKYPLLAIAKHCTETGRIPTLVTMGGIWSNHLHATAYVAAESGYKSIGLVRGNVAMNSAMLEDCRAQGMQIQFVERDTYRALRDIPHYWQNIVASGSDQFWFPEGGSDPAALHGVAELIAELPFIPDTILVACGTAATLAGLLAGLQGRSRVVGIAVLKNADYLHGEIARLLQEAGYPAHQNYQLITDFHHGGYAKVTPELRQFCHDFTEQSQVPIEPVYTGKVFYALRELIKSGYFQSDEKLVVLHTGGLQGARGMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2F9</accession>
    <name>A0A2S9H2F9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Choline dehydrogenase and related flavoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_1344</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94171">
        <property type="protein sequence ID" value="PRC94171"/>
        <property type="gene ID" value="S2091_1344"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="PTHR11552"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000137">
        <property type="entry name" value="Alcohol_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00623">
        <property type="entry name" value="GMC_OXRED_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00624">
        <property type="entry name" value="GMC_OXRED_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GMC_OxRdtase_N" evidence="4">
        <location>
            <begin position="83"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="domain" description="GMC_OxRdtase_N" evidence="5">
        <location>
            <begin position="264"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="93"/>
            <end position="96"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="221"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000137-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS00623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS00624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC94171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="544" mass="59482" checksum="C4E6503909BE9439" modified="2018-07-18" version="1">MTEIVFDYIVIGGGSGACATAGRLSEDSTKTVLVLEAGGEGKDWAIRIPAGAITMLPTKYNNWAFQTVPQAGLNGRRGYQPRGKALGGSSVLNAMVYIRGQASDYDHWAALGNTGWSFNELLPYFKRAENNADFTDAFHGNNGPLHVGKLRTDNPFQQIYLNAAQQAGFPLNNDFNGVSQEGAGTYQVTQFNGERWSAARAYLEPHRATRSNLHVMTGAHVTQILFEDEEVAIANQKRAVAVKFTHNGQVKTARAKSEIILAAGALQSPQLLMLSGVGDRTELEKLGIPVVHHLPGVGNNLQDHPDMVLNYTANSLDLMGFSVSGAWRMARECWRYITKRRGMLSTNYAEGGAFLKTSPELPSPDVQLHFVIGVVEDHARKLRWGHGYSCHVCILRPKSRGSVRLASANPHTAPLIDPNFFSDPDDLEVMLKGLKLTQKLMDAPALKNIRTSALTDADAHSDDELRELIRQRADTVYHPVGSCKMGLDAMSVVDPQLRVYGVKGLRIADASIMPTLISGNTNAICMVIGEKAAEFIFNEKHDET</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2L7</accession>
    <name>A0A2S9H2L7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Lysine-2,3-aminomutase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0829</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94208">
        <property type="protein sequence ID" value="PRC94208"/>
        <property type="gene ID" value="S2091_0829"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025895">
        <property type="entry name" value="LAM_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003739">
        <property type="entry name" value="Lys_aminomutase/Glu_NH3_mut"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30538">
        <property type="entry name" value="PTHR30538"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12544">
        <property type="entry name" value="LAM_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LAM_C" evidence="2">
        <location>
            <begin position="116"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="1">
        <location>
            <position position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR603739-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="192" mass="21263" checksum="3384F643F3FCA170" modified="2018-07-18" version="1">MKITADHAWTDALTQISDLGRARGVEVSLHTHFNHPTEITSFVVQASNTLFSRGVMVRNQTVLLRGVNDNSQTLGMLVKRLGDLHIHPYYVYLCDPVLGIEDMRVDVATACRLEKEIRGLTAGYNMPAFVVDAPGGGGKRLVHSYEAYNADSGLVSFAAPAVKRGKLFLYPDPLHTLSPANRQRWFDPETAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2P4</accession>
    <name>A0A2S9H2P4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Esterase/lipase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_0873</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 'GDXG' lipolytic enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94252">
        <property type="protein sequence ID" value="PRC94252"/>
        <property type="gene ID" value="S2091_0873"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002168">
        <property type="entry name" value="Lipase_GDXG_HIS_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01173">
        <property type="entry name" value="LIPASE_GDXG_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015708901" evidence="3">
        <location>
            <begin position="23"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="domain" description="Abhydrolase_3" evidence="4">
        <location>
            <begin position="106"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC94252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="340" mass="36675" checksum="4EF4A0B8DFFE1476" modified="2018-07-18" version="1">MKNMNKVFAATAISLTIGNAMAAAGSPGVEHTTQAFLEALETGFGTPFEQLSPAEARTKFDGAQAGVKLVLPKADVSEKIIEVDGAAIKLTIVRPAGVTKTLPAFMFFHGGGWVLGDFASHERLVRDLVVNSGAVAVFVNYTPSPDAKYGVAINQAYAATKWVAEHGKEINVDGSRLAVAGNSVGGNMATVVSIMAKERGAPKLRFQALLWPVTDANMDNASYQQFGENHFLTKSAMKWYWDNYTSNLEQRNEIYASPLRASLAQLQGLPPALIETAEFDVLRDEAEAYGHKLDAAGVEVTSMRYSGMIHDFGLLNVLSQVPAVRSAMRQAGEELKQHLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2Q1</accession>
    <name>A0A2S9H2Q1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0883</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94262">
        <property type="protein sequence ID" value="PRC94262"/>
        <property type="gene ID" value="S2091_0883"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="60" mass="6354" checksum="329DC74EE1860395" modified="2018-07-18" version="1">MSEDVLDVETIDACKMGIGAQALISSSTNAPTIMNAERAVGVVMPATQYYSNCVDNLEKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2S4</accession>
    <name>A0A2S9H2S4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0878</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94257">
        <property type="protein sequence ID" value="PRC94257"/>
        <property type="gene ID" value="S2091_0878"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012467">
        <property type="entry name" value="DUF1684"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41913">
        <property type="entry name" value="PTHR41913"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07920">
        <property type="entry name" value="DUF1684"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015758751" evidence="1">
        <location>
            <begin position="25"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="312" mass="33978" checksum="3FA04180C56F8DBF" modified="2018-07-18" version="1">MKIIPSSLISALVIGLTLCASTCAAPGDNYITSLDAWRKQADEKIRSEDGPLSAIGLYWLHDGINKVGAYPSNEVVLPSSLAPTKAGIIKVDGPTVTFDTVDNVVVAVDGQDTKHVTLQKDGKIDQNNFKLGRLKFSFVNRELGLAIRVTDPNNAARRDFPGQQWFPADESWVLEGHFVPFDAPKTLVYEAATGGTRTGISPGYVSFNHDGHEYRLEVQKTSETSYLAFFFDASTGKATYAGGRVVPIEKLTGDLVKLDFNKAFNMPCAVSAFFNCQIAPQQNHLTALEIPAGEKKPLVRVQRVASAPDYIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2Y1</accession>
    <name>A0A2S9H2Y1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Response regulator receiver domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0914</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94293">
        <property type="protein sequence ID" value="PRC94293"/>
        <property type="gene ID" value="S2091_0914"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="3"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="137" mass="15366" checksum="89367B6399F2706F" modified="2018-07-18" version="1">MLKILLIEDSLILRERLGTLINAIPNAVLVAQADNEDHARTCLQQVQPDIAIIDLRLKRGSGLTLIEHINFMYSDITTIVLTNFVQREYQARCMALGAHYFFDKTKGSEACINLLTALCKHSCDVVPIAEMHRGIES</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2Z3</accession>
    <name>A0A2S9H2Z3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">TupA-like ATPgrasp</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0973</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94352">
        <property type="protein sequence ID" value="PRC94352"/>
        <property type="gene ID" value="S2091_0973"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029465">
        <property type="entry name" value="ATPgrasp_TupA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14305">
        <property type="entry name" value="ATPgrasp_TupA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="277" mass="32048" checksum="D99BAD42C60BF192" modified="2018-07-18" version="1">MRAFADLIRARQSELWSAITQSGHPQVCEHELRTRFDDFAHWKCCPQWHRKLSHKLNAKEFAAKCGVRVANLYWYGTDPAAIPFDTLPTSYVIKLSNGANSEQVIPVRNGTFDVLKERHISHTTIEQTLNEMRGVVADPNAGIIVEEFIGSAEEGLPHDYKFFCFHGVAKVLYVCDRHRNTLTWYDRDWNLIRDPMHTMRNFGPTEERPINLEAMLETAELLARSYEFPFVRIDIYCPQDVGPTFGEFTHTPFGDSLDFFTPFANKWLGQFWERSGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2Z8</accession>
    <name>A0A2S9H2Z8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Polysaccharide deacetylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0969</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94348">
        <property type="protein sequence ID" value="PRC94348"/>
        <property type="gene ID" value="S2091_0969"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002509">
        <property type="entry name" value="NODB_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01522">
        <property type="entry name" value="Polysacc_deac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="SSF88713"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NodB homology" evidence="1">
        <location>
            <begin position="161"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01522"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="272" mass="30939" checksum="8C570050EE1C727D" modified="2018-07-18" version="1">MGIHLLHGCAPTWVQHRQSFRNYVPENRLWTYLKSLEQKYVPWSKHGINHHVLTVDDSTQGAARACVLARELGHHVILFVNPLQIIRQVPYFFSLLDELLDQCANHTVTYGGIKYELYGLTVTRSLRRVLKADLLTISDEAALQRVRELAREFDAPDLNISHHAQTMSIDELREISSLGVEIANHGWSHLEISHLNHEQVAAHILDGQKWIQQEIGLPAEHYAVPFGTSFVSDAAQVLVRGITMLANSSLPQGELRPGQWNRFELTEELQKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3C5</accession>
    <name>A0A2S9H3C5_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Peptide deformylase</fullName>
            <shortName evidence="2">PDF</shortName>
            <ecNumber evidence="2">3.5.1.88</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Polypeptide deformylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">def</name>
        <name evidence="4" type="ORF">S2091_1100</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>H2O + N-terminal N-formyl-L-methionyl-[peptide] = formate + N-terminal L-methionyl-[peptide]</text>
            <dbReference type="Rhea" id="RHEA:24420"/>
            <dbReference type="Rhea" id="RHEA-COMP:10639"/>
            <dbReference type="Rhea" id="RHEA-COMP:10640"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:49298"/>
            <dbReference type="ChEBI" id="CHEBI:64731"/>
            <dbReference type="EC" id="3.5.1.88"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="2">Binds 1 Fe(2+) ion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the polypeptide deformylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.88" evidence="2"/>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94479">
        <property type="protein sequence ID" value="PRC94479"/>
        <property type="gene ID" value="S2091_1100"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042586">
        <property type="term" value="F:peptide deformylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00487">
        <property type="entry name" value="Pep_deformylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.45.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00163">
        <property type="entry name" value="Pep_deformylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023635">
        <property type="entry name" value="Peptide_deformylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036821">
        <property type="entry name" value="Peptide_deformylase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10458">
        <property type="entry name" value="PTHR10458"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01327">
        <property type="entry name" value="Pep_deformylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004749">
        <property type="entry name" value="Pep_def"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01576">
        <property type="entry name" value="PDEFORMYLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56420">
        <property type="entry name" value="SSF56420"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00079">
        <property type="entry name" value="pept_deformyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="164"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="172"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="135"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="92"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="134"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="138"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC94479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="187" mass="21135" checksum="CE5E06E11CFAB9ED" modified="2018-07-18" version="1">MTILTILRYPDKRLHKIAKPVTNFDDRLKKLVADMAETMYEAPGVGLAASQVDEHIQLVVIDVSETQNELQVLINPEITWASEEKILYDEGCLSVPGIYDGVERSTEVNVRALNLDGKPFELNADGLLAVCVQHELDHLKGIVFVEYLSPLKRNRIKTRMLKEERELERSSGRGNNAASQAPRRNRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3I3</accession>
    <name>A0A2S9H3I3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0545</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94542">
        <property type="protein sequence ID" value="PRC94542"/>
        <property type="gene ID" value="S2091_0545"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045694">
        <property type="entry name" value="DUF6058"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19531">
        <property type="entry name" value="DUF6058"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="213" mass="24290" checksum="816C948604878CDB" modified="2018-07-18" version="1">MELIHYLNNEFFTQQQLLVASEIDLSELETLQLKGLMPRPSYSLKLDLSCNSFFGLHQEQANLDYYAKSYAGWIAEIRPLTSSADAFRLFSDRYKARLRQLYAALDLRTHNEKLNAGLDAHITSEWTHFLAGIYGLCTKSGLPEDIAAKELAIMIINQITELRANPILSQTERARLTVAVNLLDEASSSFAPHEVLRSSRHRLIDQMRINYSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3M1</accession>
    <name>A0A2S9H3M1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">MMSDH: methylmalonate-semialdehyde dehydrogenase (Acylating)</fullName>
            <ecNumber evidence="3">1.2.1.18</ecNumber>
            <ecNumber evidence="3">1.2.1.27</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0536</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.18" evidence="3"/>
    <dbReference type="EC" id="1.2.1.27" evidence="3"/>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94533">
        <property type="protein sequence ID" value="PRC94533"/>
        <property type="gene ID" value="S2091_0536"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018478">
        <property type="term" value="F:malonate-semialdehyde dehydrogenase (acetylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004491">
        <property type="term" value="F:methylmalonate-semialdehyde dehydrogenase (acylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07085">
        <property type="entry name" value="ALDH_F6_MMSDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010061">
        <property type="entry name" value="MeMal-semiAld_DH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43866">
        <property type="entry name" value="PTHR43866"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01722">
        <property type="entry name" value="MMSDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldedh" evidence="2">
        <location>
            <begin position="20"/>
            <end position="480"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="501" mass="53406" checksum="1584935098A280A1" modified="2018-07-18" version="1">MSSATKVGHLIHGELVTTGSRSQPIYNPATGEATKQVMLADAETMEAAIASAHAAFPAWRNTPALKRAQVMGRLKVLLEQNAEQICQLITDEHGKVLNDAQGELQRGIENVEYASYAPELLKGEHSKNVGPSIDSWSEFQPLGVTAGITPFNFPAMVPLWMWPMAVACGNTFILKPSERDPSSTLLIAQLALQAGLPKGVLNVVNGDKVAVDAILTDPRIQAVSFVGSTPIAEYIYSTGCAHGKRVQALGGAKNHSVVMPDADINNAVSALMGAAFGSCGERCMAIPLVVAVGDATADALIAGLKTEIAKMKVGPGTDISNDMGPLITKPHFDKVSDYVAIGVAEGADLVVDGRGLKVAGHEQGYFLGACLFDNVKPGMRIYQEEIFGPVLGIVRVTSLEAAMALINAHEYGNGTCIFTRDGEAARYFSDHIQVGMVGINVALPVPVAYHSFGGWKRSLFGDLHAYGPDAVRFYTKRKTITQRWPSAGVREGTTFSFPTNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3S4</accession>
    <name>A0A2S9H3S4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ABC-type antimicrobial peptide transport system ATPase component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_0623</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94620">
        <property type="protein sequence ID" value="PRC94620"/>
        <property type="gene ID" value="S2091_0623"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03255">
        <property type="entry name" value="ABC_MJ0796_LolCDE_FtsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017911">
        <property type="entry name" value="MacB_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-1278">Translocase</keyword>
    <feature type="domain" description="ABC transporter" evidence="7">
        <location>
            <begin position="2"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="38"/>
            <end position="45"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC94620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="231" mass="25639" checksum="909F7175B38D09A0" modified="2018-07-18" version="1">MLRMNNLSKVYRTHMIETHALRGFEIHVKEGEFVTVTGPSGSGKTSFLNIAGLLEVFSSGEYLLDGVDVKNLSDNERSRLRNEKLGFIFQGFNLIPDLNLFDNVDVPLRYRGFNRGERKDRIENALAQVGLASRMKHFPAELSGGQQQRVAIARALAGSPRLLLADEPTGNLDTQMARSVMELLEEINSQGTTILMVTHDPELALRSQRNVHIIDGQVSDLVRISPSLVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3X4</accession>
    <name>A0A2S9H3X4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="11">TonB family C-terminal domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">S2091_0688</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
            <orientation evidence="1">Periplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TonB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94685">
        <property type="protein sequence ID" value="PRC94685"/>
        <property type="gene ID" value="S2091_0688"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006260">
        <property type="entry name" value="TonB/TolA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037682">
        <property type="entry name" value="TonB_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03544">
        <property type="entry name" value="TonB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01352">
        <property type="entry name" value="tonB_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="TonB_C" evidence="10">
        <location>
            <begin position="156"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="48"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="56"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="75"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF03544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC94685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="237" mass="25200" checksum="266C7AE341AB9640" modified="2018-07-18" version="1">MPTTPFSYRFRNALATLPSLLILSILIIAGVQKAVKIERHVDEATVQISLSAPEPEPESVPKPPTPPTPVNQPTVKPISQPTARQETVTNSPSAEVAAAVPVALNTPVTNPTPTPTLMPTPAPVASAAEPAKPNNASIEAGYIAKLRAHLNSIKRYPTGREASQQKPQGKVKVWFVLSRNGAVVEQGIEESSNSMLLDDAAKKTINRSSFTAFPESSWAGEATHKFSAELDFIPAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H437</accession>
    <name>A0A2S9H437_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0745</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94742">
        <property type="protein sequence ID" value="PRC94742"/>
        <property type="gene ID" value="S2091_0745"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="151" mass="16656" checksum="ABA56E7F9AA17DEE" modified="2018-07-18" version="1">MTARAATQEPVASESRDAAIGFTLTQNYMIGRTASYCFEDLGRPDTPKEFVAGWQKQNSKHYSAAITYMNRRLAEAESLTGVEGKNNIANALLAAVRKNGDKAVNGFFENKDKHDECKKVIGLMESGAFNIDSRIPMYGELEALVNYIDGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H447</accession>
    <name>A0A2S9H447_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0706</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94703">
        <property type="protein sequence ID" value="PRC94703"/>
        <property type="gene ID" value="S2091_0706"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="112" mass="11928" checksum="4196D977A53E0403" modified="2018-07-18" version="1">MVYYIAYFFGGAFLANSIPHITNGMSGRPFPTPFATPPGQGESSSMLNVIWGALNIIIGYCLLFQLSDFNARSLLDLSTAGSGGLAIALYLSRRFGNVYGGIKAGSKKVDHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4B8</accession>
    <name>A0A2S9H4B8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Tat (Twin-arginine translocation) pathway signal sequence</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0027</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94832">
        <property type="protein sequence ID" value="PRC94832"/>
        <property type="gene ID" value="S2091_0027"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000674">
        <property type="entry name" value="Ald_Oxase/Xan_DH_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008274">
        <property type="entry name" value="AldOxase/xan_DH_Mopterin-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037165">
        <property type="entry name" value="AldOxase/xan_DH_Mopterin-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012368">
        <property type="entry name" value="OxRdtase_Mopterin-bd_su_IorB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019546">
        <property type="entry name" value="TAT_signal_bac_arc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02738">
        <property type="entry name" value="Ald_Xan_dh_C2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036389">
        <property type="entry name" value="IOR_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01008">
        <property type="entry name" value="Ald_Xan_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56003">
        <property type="entry name" value="SSF56003"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01409">
        <property type="entry name" value="TAT_signal_seq"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ald_Xan_dh_C" evidence="1">
        <location>
            <begin position="225"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="741" mass="78607" checksum="7CBA487D8BE2A4E3" modified="2018-07-18" version="1">MRIEWMNAQLTEVDNNAAADVGITRRSFLKAASVVGGGLILGFFVPGANKFALAANEKKAITPNAFLRIAPDNTITVAINRLEFGQGVTTSLTMLIAEELDADWSHMRAELAPAGDVFKDPIFGMQMTGGSSSVKNSYTQYREIGAAARAMLIAAAAKQWQVTVAECSAKNSMVTGPLGYKASFGSLAEAAMQQAVPEKVALKDPKYFQLIGKPTLRIDSFAKSTGTQKFGIDFSLPNMKVAVVARAPVFGGTVASLDASNALAIKGVQHVVKVATDRGGSGVAVIADGYWPAKQGRDALLVKWNSGNVAKVDTAQQFAAFKALAKTPGTVAKKADISALAGAAKKISAEYEFPYLAHAPMEPLNCVVDLSDAACTVWAGSQFQTFDQAAVARTAGLKPEQVTFNTMMAGGGFGRRGVPTSDYIVEAVQVAKAYRAQGKTGPIKVIWSREDDIKGGYYRPSHLHLAEIGFDKQGNMLAWDHTVVGQSILIGTPLEKMAVKDGVDETMIEGLGGPYNVPMKISVHNAEANVPVLWYRSVGSTHTAFVMETLLDEAAHLAGSDPVAYRKKLLGADHPRHIAALDLAVQTSGYGKTKLAKGHAFGVAMHESFNSVVAYVVEASVTKGVPKLHKVWAGVHCNQAVNPLTIEAQVQGAALMALGTTLPGSAITFKDGVVEQQNFNDYTVARMNDMPVVSVAVVPSFDPPTGMGEPGFPPLAPAFANAIAKLTGKRLRKLPFDLEKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4D7</accession>
    <name>A0A2S9H4D7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Bacterial Ig-like domain (Group 2)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0013</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94818">
        <property type="protein sequence ID" value="PRC94818"/>
        <property type="gene ID" value="S2091_0013"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003343">
        <property type="entry name" value="Big_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008964">
        <property type="entry name" value="Invasin/intimin_cell_adhesion"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02368">
        <property type="entry name" value="Big_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00635">
        <property type="entry name" value="BID_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49373">
        <property type="entry name" value="SSF49373"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BIG2" evidence="2">
        <location>
            <begin position="55"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="domain" description="BIG2" evidence="2">
        <location>
            <begin position="140"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="domain" description="BIG2" evidence="2">
        <location>
            <begin position="322"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="409" mass="41114" checksum="DBC391E3AEA894D4" modified="2018-07-18" version="1">MTNYIDSKLIFFDLKRCLILFFIFMMTACGGGGGGSSSNSSNPTQSTATATPPPTLQSINVTPTSSSMAIGSTRQYIATGKYSDGTSQAIQSPTWSSSSIANATISSTGLATSLQPGNTEITASSNGVTGSANLTITAASLQSIVVTASSTNIPLTFTEQFLATGHYSDGSTQELPSAIWSSSANTVATVNSTGLVTSTQSGSTTISASVNGITGSLAISVTTATPSSISIVENYGTSSYLPQASIPTTLYLGSVIQLTPLVLYTDGSSMVLSLPVNSTSINTVATITSTGVLTPVASGTAVVSVSFSGFTASITFTVSSATLTSVAISPSSFSVSPSSSQTLTATATYSDGTSQVIQEQVVQPITWSSSANNVATVSQGVVNWVSAGNAVITATFGGKSGTASVTLSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4I7</accession>
    <name>A0A2S9H4I7_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Pyridoxine/pyridoxamine 5'-phosphate oxidase</fullName>
            <ecNumber evidence="6">1.4.3.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">PNP/PMP oxidase</fullName>
            <shortName evidence="6">PNPOx</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Pyridoxal 5'-phosphate synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">pdxH</name>
        <name evidence="11" type="ORF">S2091_0046</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>H2O + O2 + pyridoxamine 5'-phosphate = H2O2 + NH4(+) + pyridoxal 5'-phosphate</text>
            <dbReference type="Rhea" id="RHEA:15817"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:58451"/>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
            <dbReference type="EC" id="1.4.3.5"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>O2 + pyridoxine 5'-phosphate = H2O2 + pyridoxal 5'-phosphate</text>
            <dbReference type="Rhea" id="RHEA:15149"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:58589"/>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
            <dbReference type="EC" id="1.4.3.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6 8">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
        <text evidence="6 8">Binds 1 FMN per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="6">Cofactor metabolism; pyridoxal 5'-phosphate salvage; pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="6">Cofactor metabolism; pyridoxal 5'-phosphate salvage; pyridoxal 5'-phosphate from pyridoxine 5'-phosphate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the pyridoxamine 5'-phosphate oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.4.3.5" evidence="6"/>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94851">
        <property type="protein sequence ID" value="PRC94851"/>
        <property type="gene ID" value="S2091_0046"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA01068">
        <property type="reaction ID" value="UER00304"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004733">
        <property type="term" value="F:pyridoxamine-phosphate oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008615">
        <property type="term" value="P:pyridoxine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01629">
        <property type="entry name" value="PdxH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000659">
        <property type="entry name" value="Pyridox_Oxase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019740">
        <property type="entry name" value="Pyridox_Oxase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011576">
        <property type="entry name" value="Pyridox_Oxase_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019576">
        <property type="entry name" value="Pyridoxamine_oxidase_dimer_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10851">
        <property type="entry name" value="PTHR10851"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10590">
        <property type="entry name" value="PNP_phzG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01243">
        <property type="entry name" value="Putative_PNPOx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000190">
        <property type="entry name" value="Pyd_amn-ph_oxd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00558">
        <property type="entry name" value="pdxH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01064">
        <property type="entry name" value="PYRIDOX_OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3 6 8" id="KW-0288">FMN</keyword>
    <keyword evidence="4 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5 6" id="KW-0664">Pyridoxine biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Putative_PNPOx" evidence="9">
        <location>
            <begin position="33"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="PNP_phzG_C" evidence="10">
        <location>
            <begin position="170"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="7"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="6 7">
        <location>
            <begin position="189"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6 8">
        <location>
            <begin position="60"/>
            <end position="65"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="65"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 8">
        <location>
            <begin position="75"/>
            <end position="76"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 8">
        <location>
            <position position="81"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 8">
        <location>
            <position position="82"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 8">
        <location>
            <position position="104"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="122"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="126"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="130"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 8">
        <location>
            <begin position="139"/>
            <end position="140"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 8">
        <location>
            <position position="183"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 8">
        <location>
            <position position="193"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007301"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000190-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000190-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF10590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC94851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="211" mass="24333" checksum="8D9E6494D75566C9" modified="2018-07-18" version="1">MTLANIRTDYQRASLSEEQVDADPIKQFSIWFQEALDAKVAEPNAMSLATVNQQGRPSSRIVLIKELDQRGITWYTHYTSRKGEELATNPHAALLFFWSELERQVRIEGRVEKVTALENDTYFNSRPLASRLGALASEQSQVIANRALLDERVEKITAQYGDQVPRPEHWGGYRLVPDYLEFWQGRSSRLHDRIAYEKNADGVWLRSRLQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4Y4</accession>
    <name>A0A2S9H4Y4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0245</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95050">
        <property type="protein sequence ID" value="PRC95050"/>
        <property type="gene ID" value="S2091_0245"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043683">
        <property type="term" value="P:type IV pilus assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032092">
        <property type="entry name" value="PilW"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16074">
        <property type="entry name" value="PilW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC95050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="313" mass="33588" checksum="8F1F4856C1B2909E" modified="2018-07-18" version="1">MPINQPRHHSHHQLGLTLVELMIAITLGLFVILAVTGLVFASKSSYSIQTDAAIMQDTATVALSNIARSVKQAGYVNWDKEDAPFMITDEMSPNISGLDGTSLHATSAGIKDLVSSPANTNSSDVLAVRFFGSGTAFAADNTMLNCAGFGVKTPAHDKVDASRGWSIYYVANDAGGEPELRCKYSGKKSFSSTAIARGIESFQVLYGIDITGDGIANKFLSATEVDGLDSNIAAQDLKKKTNWKKVTAIKVALLLHGTEQSRTDQSNIVHYLFGKEYTGSGNDKGTEINENSLSPGRLRTVYSTTIQLRNSLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H597</accession>
    <name>A0A2S9H597_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Acyl carrier protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_0354</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95159">
        <property type="protein sequence ID" value="PRC95159"/>
        <property type="gene ID" value="S2091_0354"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="4">
        <location>
            <begin position="1"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="3">
        <location>
            <position position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC95159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="84" mass="9291" checksum="387E2C2558062705" modified="2018-07-18" version="1">MLELEVKNLIIEVLQLEDISAADIDSDAPLFVEGLGLDSIDALELGVALQKRYGITLSADSEDTRRHFASVRALTELIEHARKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5H1</accession>
    <name>A0A2S9H5H1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0430</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95235">
        <property type="protein sequence ID" value="PRC95235"/>
        <property type="gene ID" value="S2091_0430"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="24"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC95235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="50" mass="5718" checksum="258DBD966CC61A5A" modified="2018-07-18" version="1">MSQVPEQTEIARKKTTKDEGNPKFGRLLMVLLFSVFLIGVITWASEAYWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5I1</accession>
    <name>A0A2S9H5I1_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Poly(ethylene terephthalate) hydrolase</fullName>
            <ecNumber evidence="5">3.1.1.101</ecNumber>
            <ecNumber evidence="2">3.1.1.74</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_0444</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>(ethylene terephthalate)(n) + H2O = (ethylene terephthalate)(n-1) + 4-[(2-hydroxyethoxy)carbonyl]benzoate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:49528"/>
            <dbReference type="Rhea" id="RHEA-COMP:12420"/>
            <dbReference type="Rhea" id="RHEA-COMP:12421"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:131701"/>
            <dbReference type="ChEBI" id="CHEBI:131704"/>
            <dbReference type="EC" id="3.1.1.101"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="4">
            <dbReference type="Rhea" id="RHEA:49529"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>a butanoate ester + H2O = an aliphatic alcohol + butanoate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:47348"/>
            <dbReference type="ChEBI" id="CHEBI:2571"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17968"/>
            <dbReference type="ChEBI" id="CHEBI:50477"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="3">
            <dbReference type="Rhea" id="RHEA:47349"/>
        </physiologicalReaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the AB hydrolase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.101" evidence="5"/>
    <dbReference type="EC" id="3.1.1.74" evidence="2"/>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95249">
        <property type="protein sequence ID" value="PRC95249"/>
        <property type="gene ID" value="S2091_0444"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041127">
        <property type="entry name" value="Chlorophyllase2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12740">
        <property type="entry name" value="Chlorophyllase2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00033629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00033707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00033764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00033780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC95249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="234" mass="25445" checksum="D2E0899A4B83AC07" modified="2018-07-18" version="1">MTLTDHARTIPIQLYFPAHKESCTPTQRCPVALVSAGYGVSNLAYSFIAESLTGLGYLVVSIQHQLPGDAPLTSDGDIYKNRTPNWQRGAQNIRFVQHYLSSTYAGFDWQHPILVGHSNGGDISAWLIKESSTFASAIITLDNRRVPLPRGVAPRVLSIRASDFSADEGVLPTEDEALQFGTCIVKINGAHHNDMQDDGSPALKSKITHAIETFLRPSATDGKQYACDSSSSLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GS79</accession>
    <name>A0A2S9GS79_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4723</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000054">
        <property type="protein sequence ID" value="PRC90571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90571">
        <property type="protein sequence ID" value="PRC90571"/>
        <property type="gene ID" value="S2091_4723"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015665078" evidence="1">
        <location>
            <begin position="23"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="234" mass="25765" checksum="A603D01C7C748567" modified="2018-07-18" version="1">MYFNFKDWFSIILLSTSLTACATGGNVEPGDADYPKINAYANSVLKIHGTNPDGVPIKFAIAWAATNIHGYPVADGTCNWKSNWFEGVTTGYYVSLPIDASTKGGEYEFKVNTDAFIPGRCGWKFFGIEVYSGNQIHQKGFAFDPAAILVSKNAHLPNWAGMIQKESTKVDISCRVHAYMDAVDLSPNMTITEGDYLDCLDTDTSKKIRIILPDTINPDIELNIHARVPKTAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GS88</accession>
    <name>A0A2S9GS88_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4708</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000049">
        <property type="protein sequence ID" value="PRC90581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90581">
        <property type="protein sequence ID" value="PRC90581"/>
        <property type="gene ID" value="S2091_4708"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015573185" evidence="1">
        <location>
            <begin position="26"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="249" mass="26928" checksum="79ACF2C37EC2A897" modified="2018-07-18" version="1">MSAAQLFLAMTFSVSLIFFTEEANADTAGASVVFVGCPGDGQTGPVPPPEGTPVLVKVESKVASRLAYYRGEFGPGTFAPKGWQCRLWYGSNGSFLIVTPTAPPATFPPHPISAEGVVIMGRDGETSGRFEVAEISARFFPDVMKEFIQYVKDEKLTQSNIETKPYPQDVINKVSDRMVEFTTPANLDGFGTGMFAKSDQSIRGVAALSPESEGPNIIVLRMRLAKEQRSLTDPIIKIMESCIQKSTGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSD9</accession>
    <name>A0A2S9GSD9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4676</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000044">
        <property type="protein sequence ID" value="PRC90608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90608">
        <property type="protein sequence ID" value="PRC90608"/>
        <property type="gene ID" value="S2091_4676"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="78"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="106" mass="11645" checksum="D54D43A6E4894382" modified="2018-07-18" version="1">MNLFGDFNWQYLIGGLAIGALVSICISLNIRVQNKFKSNKKLHSQIIQWLSYLSTVAVVGFAVANIAGEVLVGKNLTISEAIIFICGCTLPIVLAFKFGFIPRINR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSI1</accession>
    <name>A0A2S9GSI1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cystathionine beta-lyase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_4629</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H2O + L,L-cystathionine = L-homocysteine + NH4(+) + pyruvate</text>
            <dbReference type="Rhea" id="RHEA:13965"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:58161"/>
            <dbReference type="ChEBI" id="CHEBI:58199"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 5">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 5">Belongs to the trans-sulfuration enzymes family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000039">
        <property type="protein sequence ID" value="PRC90679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90679">
        <property type="protein sequence ID" value="PRC90679"/>
        <property type="gene ID" value="S2091_4629"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004121">
        <property type="term" value="F:cystathionine beta-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019346">
        <property type="term" value="P:transsulfuration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000277">
        <property type="entry name" value="Cys/Met-Metab_PyrdxlP-dep_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006233">
        <property type="entry name" value="Cys_b_lyase_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43500">
        <property type="entry name" value="PTHR43500"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01053">
        <property type="entry name" value="Cys_Met_Meta_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001434">
        <property type="entry name" value="CGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01324">
        <property type="entry name" value="cysta_beta_ly_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 5" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="4">
        <location>
            <position position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR001434-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC90679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="387" mass="42329" checksum="18B3409D3947CCDF" modified="2018-07-18" version="1">MKPHPATKIIHPEYTAPEGFSAFPTAIHHASTVLFENVAAMRSSTWLDKSIYTYGLHGTPTSRTLEARLAAIEDGQHCLLAPSGLAAIALVSLAFLKSGDDVLIADNAYGPNRDLGEWLARDYGITARYYDPMIGANISDLIQDNTRLIWAEAPGSVSMEVADIPAICQAAHARNVIVALDNTWSAGIAFKPFAHGVDISMQALTKYQCGGSDVLMGALVTQDLKLHERLEVVRKLLGMGVGMDDVYLILRSLPSLPLRFSAHDLHARKIATWLKSRPEISKVLHPAMPDCPGHETWQRDFTGAGGLFSVIFDADYSEAQTDRFVDSLSLFKIGYSWGGANSLCVPYRMKAMRSNWTEKGQLVRFNIGLEDVADLIADIEQALAKMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSJ0</accession>
    <name>A0A2S9GSJ0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4582</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000038">
        <property type="protein sequence ID" value="PRC90689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90689">
        <property type="protein sequence ID" value="PRC90689"/>
        <property type="gene ID" value="S2091_4582"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC90689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="187" mass="20125" checksum="E2FB82CAD734DF20" modified="2018-07-18" version="1">MTYLASPPGSLWLNRFIHLIPPGEVLDLASGAGRNCPALLAAGNSVLALDRDPHSLAQAAELGAATLCHDLEQPSSVWPFEVDRFAGIVVCNYLHRPLFPFILSSLAPQGVLIIETFAQGNAQFGKPSNPEFLLAPDELLGLVTLMPNQPLHVVAYECGYVDQPKPALVQRICIKKSALADAHLARN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSM7</accession>
    <name>A0A2S9GSM7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_4550</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000037">
        <property type="protein sequence ID" value="PRC90724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90724">
        <property type="protein sequence ID" value="PRC90724"/>
        <property type="gene ID" value="S2091_4550"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002818">
        <property type="entry name" value="DJ-1/PfpI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018062">
        <property type="entry name" value="HTH_AraC-typ_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01965">
        <property type="entry name" value="DJ-1_PfpI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00041">
        <property type="entry name" value="HTH_ARAC_FAMILY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="2">
        <location>
            <begin position="221"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC90724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="331" mass="35896" checksum="BC220C0233D39FE3" modified="2018-07-18" version="1">MITPLNIALLVFDGVQILDVTGPAAVFGAANDAVGYSFYRVHILSELGGKVKSNCAIEIDSSSLKKMSPRSIDTLLIAGGTEDKVCEFAALQTVRKWVLKASMSARRYGSICTGAFALGEFGLIDGKQVATHWSSCFDLQTAYPDANIDSNALYVEDGKLWTSAGVTTGIDMSLALVANDLGNEIADAIAKRLVLYARRPGYQSQFSPVLKAQIDAGAPFGKLITWMQEHLVETLTVSTLAERAMMSDRNFHRKFTSATGETPANFVETIRLDHARQLLTSGLSIKEIATKTGYLNATQLSKAFNRRFGISPSFFREMNSSVPISRTDGSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GST9</accession>
    <name>A0A2S9GST9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4519</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000036">
        <property type="protein sequence ID" value="PRC90771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90771">
        <property type="protein sequence ID" value="PRC90771"/>
        <property type="gene ID" value="S2091_4519"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC90771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="167" mass="19177" checksum="3F9615B309EACB07" modified="2018-07-18" version="1">MQNIIFDKTDKGREEIISRKYHLASRLRTLLVMVDGKHSSDDLLAKVEPLGLTQASVEELEQQGYIQRQSPSVQVVTTLDDTQNSQINSIELFQVLYDFYTETIKHNLGLRGYNIQFIVERASTLQDFHDLRAPFLDAINKSQSEKKALELRDQLDELLNIVPIKST</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSV0</accession>
    <name>A0A2S9GSV0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">PEP-CTERM protein-sorting domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_4538</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000036">
        <property type="protein sequence ID" value="PRC90790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90790">
        <property type="protein sequence ID" value="PRC90790"/>
        <property type="gene ID" value="S2091_4538"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013424">
        <property type="entry name" value="PEP_exosort_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07589">
        <property type="entry name" value="PEP-CTERM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02595">
        <property type="entry name" value="PEP_exosort"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015733515" evidence="1">
        <location>
            <begin position="27"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="domain" description="PEP-CTERM" evidence="2">
        <location>
            <begin position="206"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC90790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="232" mass="23491" checksum="ECF5348D88A8172A" modified="2018-07-18" version="1">MNLTLKRVLLVLALSVASLWVTSATAQVLNFAGLKGSAEEPVLNYYNGGLGGDGSGPGTNYGITFSANALTCSGYPSGVCNTGEIPGGAGANAVFFLSGAADTMDVLNGFNTGFSFYYSSPSDAAFVNVWSGLDDTGTLLATIDLPLTKNDGDSGCGGTNFCPYDAIGVTFAGNAQSVDFGGAVNEVAFADVTIGSQKAGQTVPSSVPEPVSLWLFGIGLAALGLLRRRKAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTA8</accession>
    <name>A0A2S9GTA8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Sugar transferase, PEP-CTERM system associated</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_4351</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the bacterial sugar transferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000032">
        <property type="protein sequence ID" value="PRC90950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90950">
        <property type="protein sequence ID" value="PRC90950"/>
        <property type="gene ID" value="S2091_4351"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003362">
        <property type="entry name" value="Bact_transf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017475">
        <property type="entry name" value="EPS_sugar_tfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017464">
        <property type="entry name" value="Sugar_tfrase_EpsB_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02397">
        <property type="entry name" value="Bac_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03025">
        <property type="entry name" value="EPS_sugtrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03013">
        <property type="entry name" value="EpsB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="48"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="82"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="108"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="280"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="domain" description="Bac_transf" evidence="8">
        <location>
            <begin position="275"/>
            <end position="458"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC90950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="463" mass="52667" checksum="935E8909F214BCEE" modified="2018-07-18" version="1">MRIANHHVPQITAFLLCVEFLEAFASTYLGAMLRFLDSNYHYSPHREFFFISGIAFAVATAFSMSAFGLYRISYRKGIRNTLLRLIPSFALSFSLITLLFYLLPDLYIGRGILGLVVLIAASMIIGTRALIFKFSEVGLLKSRIAFLGCGKLANECRTLALNNTSYHHYELVGFIPTEGEECLVPVNELLTNNSDLTTVLKQHNVHEIVVSVMNRRGVQFPLQELLDCKLHGIKVIESTAFIEREACQIRVESLHPGWLIFGEGFNQSFLRKFGKQTFDLIISALIFVITSPIMLLTSIFIYLEDRGPIFFRQERVGKNNSTYMVLKFRSMRSDAEKNGVPQWACNNDPRVTRVGNIIRKLRIDELPQIINVLYGDMSFVGPRPERPYFVDQLCTEVPFYNLRHSIKPGITGMAQVRYAYGASVEDSLQKLQYDLYYVKNNSLFLDALILIDTVQVVLFGKGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTL0</accession>
    <name>A0A2S9GTL0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">GGDEF: diguanylate cyclase (GGDEF) domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_4250</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000030">
        <property type="protein sequence ID" value="PRC91062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91062">
        <property type="protein sequence ID" value="PRC91062"/>
        <property type="gene ID" value="S2091_4250"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01948">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001633">
        <property type="entry name" value="EAL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035919">
        <property type="entry name" value="EAL_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00563">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00052">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141868">
        <property type="entry name" value="SSF141868"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50883">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="7"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="3">
        <location>
            <begin position="148"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="4">
        <location>
            <begin position="222"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="6">
        <location>
            <begin position="304"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="domain" description="EAL" evidence="5">
        <location>
            <begin position="445"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="714"/>
            <end position="829"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="56"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="763"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC91062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="841" mass="94329" checksum="C2578FF00AE44600" modified="2018-07-18" version="1">MSSAAATILIVDDEPQSRKLLETLLRPEGYRTLSAANGEDALTSIGQSTPDLILLDIMMPGIDGYQVAVILKANPATANIPIIMVTALIDRSARLAGLNAGAEEFLTKPVDRAELWLRVRNLLRLKTFCALQSHSLVLEQQVQARMADLQRFRTAMDATANAIFLLNHATMHFIEVNTTACKMLGYTREELFEMDPSQLGAGTQELLQSAYYAAITGNSLTDLVETQLRRKDGTQLQVEMHRQTQPSGPDWIIVGVVRDITERKQAELRLHHLAHYDALTGLPNRTLFYESLKKIMLQTANSGWLIAVMFIDLDLFKNVNDSLGHGVGDELLRQFSNRLVECVRIRDTVGRLGGDEFALVLVMQDEQDAVIVANKIRDTLHRPFDLNGHEVTVTASIGITIYPTDASDPETLLRYADTAMYRAKHAGRDTFRFFTAQMNVEMLTRLDLEKALRQAVENNEFVLHYQPKVRLDSGRVTGMEALLRWQRPGHGLVFPGDFIPILEETGLIVRVGSWVIAAACKQIGLWAHSSIGPIQVSVNVSGRQFIEGDLDGDVIKALDDNDITADLLELELTESSMMANTDRTIASLKNLKNRGVQISVDDFGTGYSSLAYLRRFPIDKLKIDIAFIREVTSNPDDAAIVQAIIDMAHSLKLEVIAEGVETAAQLEYLRRHRCDQIQGYYFSRPLPVLELEQMLREERRLPKQDDEAGTPRKTLLLVDDEAHILSALQRVLRQDGYHILTAESAAEGFELLALHKVQVILCDQRMPTMNGTVFLDLVKDMYPNTLRIILSGYIDVESILNAINRGAIYRFYTKPWDNKVLRDNICEAFQHHSLLHGVPLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTQ1</accession>
    <name>A0A2S9GTQ1_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Bis(5'-nucleosyl)-tetraphosphatase (symmetrical)</fullName>
            <ecNumber evidence="4">3.6.1.41</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Ap4A hydrolase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Diadenosine tetraphosphatase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">S2091_4191</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H2O + P(1),P(4)-bis(5'-adenosyl) tetraphosphate = 2 ADP + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:24252"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58141"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.1.41"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the Ap4A hydrolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.41" evidence="4"/>
    <dbReference type="EMBL" id="PUGF01000029">
        <property type="protein sequence ID" value="PRC91095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91095">
        <property type="protein sequence ID" value="PRC91095"/>
        <property type="gene ID" value="S2091_4191"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008803">
        <property type="term" value="F:bis(5'-nucleosyl)-tetraphosphatase (symmetrical) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07422">
        <property type="entry name" value="MPP_ApaH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004617">
        <property type="entry name" value="ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP_ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000903">
        <property type="entry name" value="B5n-ttraPtase_sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00668">
        <property type="entry name" value="apaH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallophos" evidence="9">
        <location>
            <begin position="15"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012506"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00031248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00032248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00033210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC91095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="283" mass="31895" checksum="E76410DA3769950F" modified="2018-07-18" version="1">MNSIANNTMTNTEHIYVVGDLQGCCDQFNELHAQILLQDPDATLFIAGDLVNRGPQSLPTLRKLVALGDRANSVLGNHDLNLLGIAYGAHRPHHDAYLRPILDAPDREQLLDWLRHRPLAFQIEQHLIIHAGVLPSWTVEQTLDYAREVEQMLQGPNYVDFLRVMYSNQPSVWSTTLTGMDRLRCIVNVLTRLRFCTISDEMEFDSKEGLNKTPPGFAPWFSHPRLSASSTLIYGHWSAIGLQLQPNLIGLDTGCVWGGKLTAMRLSDHQLFQVDCPPHQEIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GU07</accession>
    <name>A0A2S9GU07_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">NAD(P)H:quinone oxidoreductase, type IV</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_4084</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the WrbA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000027">
        <property type="protein sequence ID" value="PRC91189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91189">
        <property type="protein sequence ID" value="PRC91189"/>
        <property type="gene ID" value="S2091_4084"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003955">
        <property type="term" value="F:NAD(P)H dehydrogenase (quinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008254">
        <property type="entry name" value="Flavodoxin/NO_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001226">
        <property type="entry name" value="Flavodoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010089">
        <property type="entry name" value="Flavoprotein_WrbA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005025">
        <property type="entry name" value="FMN_Rdtase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03358">
        <property type="entry name" value="FMN_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="SSF52218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01755">
        <property type="entry name" value="flav_wrbA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00201">
        <property type="entry name" value="FLAVODOXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50902">
        <property type="entry name" value="FLAVODOXIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0288">FMN</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavodoxin-like" evidence="5">
        <location>
            <begin position="11"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC91189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="204" mass="21254" checksum="DE56EA1B7B96C40E" modified="2018-07-18" version="1">MPAMKTSNITLLVLFYSRHGATKKMADFIAQGIESVPGCSARLRTVPAISTVCEATQSDVPTDGAPYVELSDLSECAGIALGSPTRFGNMASAMKYFWDGTAADWLSGTLNGKPACVFTSTGSLHGGQESTLLSMMLPLLHHGMLILGLSYSHPALMSTSSGGTPYGASHWAGADGSKAISEDSKQLAIALGVRLAKTAQQLNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GU14</accession>
    <name>A0A2S9GU14_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Arginine/lysine/ornithine decarboxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_4012</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Orn/Lys/Arg decarboxylase class-I family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000026">
        <property type="protein sequence ID" value="PRC91227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91227">
        <property type="protein sequence ID" value="PRC91227"/>
        <property type="gene ID" value="S2091_4012"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016831">
        <property type="term" value="F:carboxy-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:cellular amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005308">
        <property type="entry name" value="OKR_de-COase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011193">
        <property type="entry name" value="Orn/lys/arg_de-COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000310">
        <property type="entry name" value="Orn/Lys/Arg_deCO2ase_major_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008286">
        <property type="entry name" value="Prn/Lys/Arg_de-COase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036633">
        <property type="entry name" value="Prn/Lys/Arg_de-COase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01276">
        <property type="entry name" value="OKR_DC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03711">
        <property type="entry name" value="OKR_DC_1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03709">
        <property type="entry name" value="OKR_DC_1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF009393">
        <property type="entry name" value="Orn_decarb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55904">
        <property type="entry name" value="SSF55904"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00703">
        <property type="entry name" value="OKR_DC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OKR_DC_1" evidence="4">
        <location>
            <begin position="392"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="3">
        <location>
            <position position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR009393-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC91227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="753" mass="85010" checksum="3F2626D6A9DA3631" modified="2018-07-18" version="1">MKFRFPIVIIDEDFRSENSSGLGIRALAHAMEAEGMEILGVTSYGDLSQFAQQQSRASAFILSIDDEEFGGGSPEEIDFALTSLRAFVEEIRYKNSDIPIYLYGETRTSRHIPNDILRELHGFIHMFEDTPEFVARHIIREAKAYLDGLAPPFFRALVQYANDGSYSWHCPGHSGGVAFLKSPIGQMFHQFFGENMLRADVCNAVEELGQLLDHTGPVAASERNAARIFNADHCYFVTNGTSTSNKMVWHSTVAPGDIVVVDRNCHKSILHSIIMTGAIPVFLMPTRNHLGIIGPIPLSEFTMENIQKKIDANPFARAAKNKQPRILTITQSTYDGVIYNVETLKEMLDGKIDTLHFDEAWLPHATFHSFYQDMHAIGPNRPRAKESMIFSTQSTHKLLAGLSQASQILVRESENNKLDRDRFNEAYLMHTSTSPQYSIIASCDVAAAMMEAPGGTALVEESIFEALDFRRAMRKIDQEWGQDWWFQVWGPDNLCEDGIGSREDWIIRAEDNWHGFGKLAPNFNMLDPIKATIITPGLSLEGHFSETGIPASIVTKYLAEHGVIIEKCGLYSFFIMFTIGITKGRWNTLLTALQQFKDDFDKNQPMWRVLPEFVANNPRYESIGLRDLCQQIHQAYQAHDVARLTTEMYLSDMEPAMKPSDAFAKMAHREIERVSIDDLEGRVTAILLTPYPPGIPLLIPGECFNKTIVDYLKFARDFNHRFPGFDTDVHGLVTRVENGVKNYYVDCVRADCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GU68</accession>
    <name>A0A2S9GU68_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_4038</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000026">
        <property type="protein sequence ID" value="PRC91253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91253">
        <property type="protein sequence ID" value="PRC91253"/>
        <property type="gene ID" value="S2091_4038"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010559">
        <property type="entry name" value="Sig_transdc_His_kin_internal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06580">
        <property type="entry name" value="His_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015511847" evidence="2">
        <location>
            <begin position="20"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="30"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="60"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="93"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="124"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="domain" description="His_kinase" evidence="3">
        <location>
            <begin position="161"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF06580"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC91253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="373" mass="42375" checksum="606C998B193B992C" modified="2018-07-18" version="1">MIIKHLRLAVSTASPSALASVIPDCCNIGVIYRVLLATNSAAFCGIWMKSKDTLSAVLEFLDSAMLLETISILSLLMLCGLRKVALVQQFPLWLQRVLCGITPALIASALSIFLSQQSWFLDDFLHASTLQLAILSAFFGMIFQHHFELRSRAFSPALVEAKLQALQARIRPHFLFNSINAVLSLIRTEPLRAETALEDLADLFRVLMRDTRDMSTLYDEVRFCRQYLSIEKIRLGERLKVEWEITNFSEKNVKEAQIASLLLQPLIENAVHHGVEPSEKQSVVTIKLNRNSERIFIVIENPYYGAHETKGNQMALDNIRERLNLLYDLEADFVATVIGNIFQVKLSFPFQKMPNVVNQRDPKVDRRSVKRVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUC7</accession>
    <name>A0A2S9GUC7_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">Protein phosphatase CheZ</fullName>
            <ecNumber evidence="7">3.1.3.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6 7">Chemotaxis protein CheZ</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">S2091_3979</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P).</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the CheZ family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.-" evidence="7"/>
    <dbReference type="EMBL" id="PUGF01000025">
        <property type="protein sequence ID" value="PRC91308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91308">
        <property type="protein sequence ID" value="PRC91308"/>
        <property type="gene ID" value="S2091_3979"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009288">
        <property type="term" value="C:bacterial-type flagellum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004721">
        <property type="term" value="F:phosphoprotein phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097588">
        <property type="term" value="P:archaeal or bacterial-type flagellum-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050920">
        <property type="term" value="P:regulation of chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007439">
        <property type="entry name" value="Chemotax_Pase_CheZ"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04344">
        <property type="entry name" value="CheZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002884">
        <property type="entry name" value="CheZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0145">Chemotaxis</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 7" id="KW-0283">Flagellar rotation</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="17"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="19"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="site" description="Enhances dephosphorylation of CheY-P" evidence="8">
        <location>
            <position position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029599"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR002884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR002884-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC91308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="249" mass="26943" checksum="7FA40435A4FF9AFC" modified="2018-07-18" version="1">MNDSDEDLEALFEEMASQPAAAAQSTPAVATQATSTTQTSSNSEEAEVDSNANKPIFERLGGVVRVLHDSMRELGYDRSLAEVTSQITDAHGRLEYIATLTEQAANKVLNATDEGMPAQDELAKKAKDIDERWTSLFKGQMSIEAFKTLASDSQKFAKDAIASTEAEKARLLSIMMSQDFQDLTGQLIKKVVTITSAVEHELAQILIDNAPAMSAILKDKPVELMEGPSVPASAMEQDDVDNLLDSLGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUH4</accession>
    <name>A0A2S9GUH4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ABC-type uncharacterized transport system permease component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3927</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000024">
        <property type="protein sequence ID" value="PRC91382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91382">
        <property type="protein sequence ID" value="PRC91382"/>
        <property type="gene ID" value="S2091_3927"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017004">
        <property type="term" value="P:cytochrome complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002541">
        <property type="entry name" value="Cyt_c_assembly"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01578">
        <property type="entry name" value="Cytochrom_C_asm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="26"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="56"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="85"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="113"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="178"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="209"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="238"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrom_C_asm" evidence="2">
        <location>
            <begin position="59"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="269" mass="29962" checksum="0C8EE2C6E427DFC8" modified="2018-07-18" version="1">MQTYLTITAAVLYASCLFLPTRLRWLISLIIVLGWSVHGTALWLEISSPAGIRLGFALMLSTATWVSVLAYWLENWKLPLEGLRILVLPGAAIQVLLPLFFPGQLISIDGKSIWFTGHIAIALLAYSTLTIAAFHAVLMAMQEARLHNRASIFSVGWIGATLERLPALLLMERILFRLVFIGFILLSLTVLTGVVFSEDVFGVVFKWDHKTIFTLLSWGLFGILLGGRRLRGWRGKTALGLTLSGFTTLLLAYVGSRFVFEVILHRSFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUI2</accession>
    <name>A0A2S9GUI2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3987</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000025">
        <property type="protein sequence ID" value="PRC91316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91316">
        <property type="protein sequence ID" value="PRC91316"/>
        <property type="gene ID" value="S2091_3987"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="96" mass="11000" checksum="BA735ADF39EC2AE9" modified="2018-07-18" version="1">MTSDDYMEESKKLTAPTMDMHRAIMSVSEKLAELDRCNQRIDACTDSSLISILAASREIEKTNIAMLLEWMRRHDPQFDHALRATLFKAGPIVEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUK4</accession>
    <name>A0A2S9GUK4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3827</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000023">
        <property type="protein sequence ID" value="PRC91412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91412">
        <property type="protein sequence ID" value="PRC91412"/>
        <property type="gene ID" value="S2091_3827"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015749093" evidence="1">
        <location>
            <begin position="24"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="182" mass="19242" checksum="AE020E87A864D64D" modified="2018-07-18" version="1">MNKLLSGLLITIVSISAYTNAFAATAEAKLTYKSALEHADAEYKINTNKCNSLASNAKDVCIEEAVLARTTLKAQANADYENTPKARATAISDVADAQYAVDKEKCNTKVGNDKDVCMKQAKATNVTSIANAKATNKVTNARGEAAQSTNDADYQVEIEKCDGFAGPSKAACIASAQTKYGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUN6</accession>
    <name>A0A2S9GUN6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="10">HAD ATPase, P-type, family IC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">S2091_3845</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000023">
        <property type="protein sequence ID" value="PRC91430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91430">
        <property type="protein sequence ID" value="PRC91430"/>
        <property type="gene ID" value="S2091_3845"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006811">
        <property type="term" value="P:ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004014">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00690">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00120">
        <property type="entry name" value="HATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00831">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="SSF81653"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="SSF81665"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-1278">Translocase</keyword>
    <keyword evidence="1 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="85"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="235"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="260"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="600"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="629"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="668"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="701"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="732"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="761"/>
            <end position="787"/>
        </location>
    </feature>
    <feature type="domain" description="Cation_ATPase_N" evidence="9">
        <location>
            <begin position="10"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="9"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC91430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="792" mass="82982" checksum="9D82571A74156BA3" modified="2018-07-18" version="1">MPPDNAKSLPIPSNDTQDSAKKSDQKSGLTTGEAHRRQEKIGFNTMPVSTENPVRMALKKIWAPVPWMLEATIVLQVVLGDYIEAAIIAGLLIFNAALGLFQEGRAQATLAALKSKLAMNAAVRRDGHWITVPAADLVPGDVVKLSLGGVVAADVRLMEGEVLLDQSMLTGESVPIEAGVGVQTYAGAFVRRGEAVAEVTETGPRTKFGRTAELIRTAHVVSSQQKAVLHVVRNLAMFNGVVIVLLVAYAHYLAMPLAEIIPLVLTAILASIPVALPATFTLASALGARALAKQGVLPTRLSAVDEAATMDVLCSDKTGTLTRNELNVTTLRPMPGFDEAHLLALAALASSDGGGDPVDAAIRATAAGKPIQEAPRLVKFVPFDPATKMSEATATDKDGVEQRIVKGAFTSIIGLVQSSPTAQAVLTELEGQGFRVLAVASGVPTAMKLLGFIALSDPPRTESAALITELRGLGVQTVMVTGDAPATAGIVAHAVGLNGATCPAGPIPPDVRPETFSVFAGVLPEGKFELVKAFQKSGHTVGMCGDGANDAPALRQAQIGIAVSTATDVAKSAAGMVLTDTGLAGVVAAVKEGRIIFQRILTYTLNSIVKKIVTVLFLILGLIMTGHAILTPLLMVIIMIAGDFLAMSLTTDNVRPSVMPNAWRIGNLTTAGVILGVCLLAFCAAVLAIGKFELMLATEALRTLAFIVLVFGSQAMIYAIRERKYLWSSRPSTWLVASSILDILIASILATWGLAMTALPISVVAGTFFSAVVFVVILDMVKVLLFARLKIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUQ6</accession>
    <name>A0A2S9GUQ6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_3858</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000023">
        <property type="protein sequence ID" value="PRC91443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91443">
        <property type="protein sequence ID" value="PRC91443"/>
        <property type="gene ID" value="S2091_3858"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="3"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="141"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC91443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="208" mass="22902" checksum="21913AF1EB814E43" modified="2018-07-18" version="1">MTKIMIVDDHPVIRLAVRVLLERGGYDVVAETDNGIDAVSLAQKNEPDILILDIGIPKLDGFQVIHRIRQAALATSVLVLSAQSSQHMITRCMQAGASGYVSKEKDLTELIDAIKAILINNYYFPRQSLGAAPSLDTTKSEMVNLNSLSNREMMVLQQLVIGNSNNDIAENMLLSPKTISTYKVRLLQKLNANSLTDLIEIAKRNSLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUS5</accession>
    <name>A0A2S9GUS5_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 4">GDP-mannose 4,6-dehydratase</fullName>
            <ecNumber evidence="3 4">4.2.1.47</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">GDP-D-mannose dehydratase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">gmd</name>
        <name evidence="6" type="ORF">S2091_3876</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>GDP-alpha-D-mannose = GDP-4-dehydro-alpha-D-rhamnose + H2O</text>
            <dbReference type="Rhea" id="RHEA:23820"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:57527"/>
            <dbReference type="ChEBI" id="CHEBI:57964"/>
            <dbReference type="EC" id="4.2.1.47"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 4">
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.47" evidence="3 4"/>
    <dbReference type="EMBL" id="PUGF01000023">
        <property type="protein sequence ID" value="PRC91461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91461">
        <property type="protein sequence ID" value="PRC91461"/>
        <property type="gene ID" value="S2091_3876"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008446">
        <property type="term" value="F:GDP-mannose 4,6-dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070401">
        <property type="term" value="F:NADP+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019673">
        <property type="term" value="P:GDP-mannose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00955">
        <property type="entry name" value="GDP_Man_dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006368">
        <property type="entry name" value="GDP_Man_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43715">
        <property type="entry name" value="PTHR43715"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16363">
        <property type="entry name" value="GDP_Man_Dehyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01472">
        <property type="entry name" value="gmd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-0521">NADP</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-bd_dom" evidence="5">
        <location>
            <begin position="6"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF16363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC91461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="353" mass="39551" checksum="8608AA4201019F49" modified="2018-07-18" version="1">MTKTAIITGITGQDGAYLAELLLSKNYTVWGTYRRTSSVNFWRIEECGIQNHPNLHLVEYDLTDLGSSISLIQKVQPDEIYNLAAQSFVGVSFDQPNTTTQITGVGALNLLEAIRLTNPKIRFYQASTSEMFGKVQAIPQIEETPFYPRSPYGVAKLYAHWMTINYRESYGIFGSSGILFNHESPLRGREFVTRKISDSVAKIKLGKLDSLDLGNIDAKRDWGFAKEYVDGMWRMLQADQPDTYVLATNRTETVRDFVRIAFKVAGIQVEFNGAAEDETAVVTAIDVECPVKIGQTVMRVNPKFYRPAEVELLIGNPAKAKAKLGWAPTTTLEQLCQMMVETDLRRNASGFSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUZ6</accession>
    <name>A0A2S9GUZ6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative LmbE-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3754</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000022">
        <property type="protein sequence ID" value="PRC91476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91476">
        <property type="protein sequence ID" value="PRC91476"/>
        <property type="gene ID" value="S2091_3754"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10320">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003737">
        <property type="entry name" value="GlcNAc_PI_deacetylase-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024078">
        <property type="entry name" value="LmbE-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12993">
        <property type="entry name" value="PTHR12993"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02585">
        <property type="entry name" value="PIG-L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102588">
        <property type="entry name" value="SSF102588"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="223" mass="25413" checksum="AED77DDA5AB55552" modified="2018-07-18" version="1">MTRKVLVIATHPDDETLGCGGTLLKHQAENHEVYWLICTSMSEKNGYTLESLETRTQEINDVASVFNFKEIYHLGLDSMQVDTYAMSEIIAKIASIIKQVEPHTIYLPFKSDVHSDHRKIFEAAYSCTKSFRYPFIKRILMMETLSETEFAPSTKEDSFIPNVFVDISAYFEKKCAILRIYKSEMGVHPFPRSERNVTALATLRGATAACEYAESFVLLKEIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GV55</accession>
    <name>A0A2S9GV55_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DnaJ domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3710</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000021">
        <property type="protein sequence ID" value="PRC91594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91594">
        <property type="protein sequence ID" value="PRC91594"/>
        <property type="gene ID" value="S2091_3710"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="SSF46565"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="1">
        <location>
            <begin position="13"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="102" mass="11530" checksum="B82B9D92718AE1DA" modified="2018-07-18" version="1">MSMALTVMNINKDLYAVLGLASTALPDEIKKAFRLKASEFHPDKNTSELAPSKFREVREAYEVLSDPVTRAVYDDNRRRNLLESPLETASEIWSTYVSGVLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVA5</accession>
    <name>A0A2S9GVA5_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 6">Thymidylate kinase</fullName>
            <ecNumber evidence="3 6">2.7.4.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5 6">dTMP kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">tmk</name>
        <name evidence="8" type="ORF">S2091_3582</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>ATP + dTMP = ADP + dTDP</text>
            <dbReference type="Rhea" id="RHEA:13517"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58369"/>
            <dbReference type="ChEBI" id="CHEBI:63528"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.9"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the thymidylate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.9" evidence="3 6"/>
    <dbReference type="EMBL" id="PUGF01000020">
        <property type="protein sequence ID" value="PRC91644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91644">
        <property type="protein sequence ID" value="PRC91644"/>
        <property type="gene ID" value="S2091_3582"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004798">
        <property type="term" value="F:thymidylate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006233">
        <property type="term" value="P:dTDP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006235">
        <property type="term" value="P:dTTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00165">
        <property type="entry name" value="Thymidylate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039430">
        <property type="entry name" value="Thymidylate_kin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018094">
        <property type="entry name" value="Thymidylate_kinase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02223">
        <property type="entry name" value="Thymidylate_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00041">
        <property type="entry name" value="DTMP_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 8" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0545">Nucleotide biosynthesis</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thymidylate_kin" evidence="7">
        <location>
            <begin position="19"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="21"/>
            <end position="28"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00017144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00029962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC91644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="212" mass="23651" checksum="ABF3BD1D22EB9393" modified="2018-07-18" version="1">MNQSNKLSKTMKTAKLITFEGIDGAGKSTHIPFVVSLLETAGHTVVSTREPGGTELGEQLRALLLHQSMHLETEALLMFAARREHIAQVIAPALERGDWVVSDRFTDASFAYQGGGRKLALAKLEALEKWVHPDLQPDLTLLFDVPLEVARSRLDAARDPDKFEQEKADFFANTRAEYLRRAAEFPARFRVINSNRPIEEIQAELSGIVQSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVF5</accession>
    <name>A0A2S9GVF5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3645</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000020">
        <property type="protein sequence ID" value="PRC91707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91707">
        <property type="protein sequence ID" value="PRC91707"/>
        <property type="gene ID" value="S2091_3645"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007497">
        <property type="entry name" value="DUF541"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04402">
        <property type="entry name" value="SIMPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015404712" evidence="1">
        <location>
            <begin position="23"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="240" mass="25994" checksum="BACE384076085140" modified="2018-07-18" version="1">MKKLFITATVVLCYLFSTQVFAQQTKGSLIVVSGTGEVKAENDQANATFFIEEQDKDKAAAAGRVNKKMKDGTEILKKADPEAKLATRGYYTYPVYSDTLSSAKTRTITGWRVGQYLELTTKNIQQLPATVAAAQQTLALNGLSFGLSDATMQRLDAARLEAAYKNMQERVQAIAKAMGRDAASAVIETLDFDGTASHPEPRMFAAAAPMMARSNSVPETNFEAGESTLTAKVVAKIKFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVH7</accession>
    <name>A0A2S9GVH7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3482</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000019">
        <property type="protein sequence ID" value="PRC91727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91727">
        <property type="protein sequence ID" value="PRC91727"/>
        <property type="gene ID" value="S2091_3482"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="184" mass="21181" checksum="D67133F3459174BC" modified="2018-07-18" version="1">MSRQFLPILFYFVIAPSISSITVGKEVPCHYEESRIVGYEMTTDFRRLSYITADGQSVFLAEAGDGAILEGDFRAARGTKSEYFEPWADVSEVRYSDPKLSRKKLLDFKIIYVPLNYALKSVDLGLSDDWKIYNYVYDYDQHKKTYDEKVWQFLVKNTMTGATNTIIASDVEKVLLARCNLKHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVM7</accession>
    <name>A0A2S9GVM7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3527</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000019">
        <property type="protein sequence ID" value="PRC91772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91772">
        <property type="protein sequence ID" value="PRC91772"/>
        <property type="gene ID" value="S2091_3527"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="296" mass="32926" checksum="B173BD0D86A1E4BA" modified="2018-07-18" version="1">MNQLEAMTIFVRVAELASFTQAADSLGLPKASVSTAVKQLENSLGTRLLQRTTRTVQMTQDGLVFYERSKDMLADMDELQTMFRQSEVDIAGRIRVDMPNGVAQNRIIPKLPEFLRRHPRIDIELSCTDRRVDLVREGFDCVIRVGTLSDSSLIARPLGHFKLLNCTSPEYLAHHGIPRNLDDLAAHKMIHYATSFGSSISTFDYQDGDQSKKIAVAAAMSVNSADAYQSACLAGLGIIQAPEIGVSELIAQGKLVEVLKEYSAAPMPVSLLYVNRRHLPKRTQLFMNWVAEIMRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVU9</accession>
    <name>A0A2S9GVU9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Flagellar motor component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_3405</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Membrane</location>
            <topology evidence="1 6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the exbB/tolQ family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000018">
        <property type="protein sequence ID" value="PRC91849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91849">
        <property type="protein sequence ID" value="PRC91849"/>
        <property type="gene ID" value="S2091_3405"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002898">
        <property type="entry name" value="MotA_ExbB_proton_chnl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01618">
        <property type="entry name" value="MotA_ExbB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9" id="KW-0966">Cell projection</keyword>
    <keyword evidence="9" id="KW-0969">Cilium</keyword>
    <keyword evidence="9" id="KW-0282">Flagellum</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="34"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="149"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="181"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="domain" description="MotA_ExbB" evidence="8">
        <location>
            <begin position="103"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC91849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="245" mass="27030" checksum="4113C74168AB8A3E" modified="2018-07-18" version="1">MDWASIAGILLAFFGLLFGQLVEGAHPSSMLQPAAFLIVFCGTMGAVLLQSRLPTFVRGVRMLRSIFQVPIDNHQKLVREALAWNMSARREGVLSLERYLRAVQDPFISKGLRMVIDGVDAVRIKEILEVDITAFEIFQRQAVRIWESAGGYSPTIGILGAVLGLIHVMENLSDPSKLGSGIAVAFVATIYGVGLANLVFLPIAHKLKEIVTRDIEKKEMLADIFYSIAAGENSRVIEERVVNYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVX7</accession>
    <name>A0A2S9GVX7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Bacterial transcriptional repressor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3417</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000018">
        <property type="protein sequence ID" value="PRC91861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91861">
        <property type="protein sequence ID" value="PRC91861"/>
        <property type="gene ID" value="S2091_3417"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025722">
        <property type="entry name" value="TetR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13972">
        <property type="entry name" value="TetR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="7"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="30"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="222" mass="26547" checksum="9E867C4DF082DD06" modified="2018-07-18" version="1">MQQKAPRRTRERILELSLKLFNEFGEPNITTTVIAEEMNISPGNLYYHFRNKDDIVNSIFVQFEEEINKKLAFPKGRKANVDDIWLYLHLTYELIWRYRFFYRDLNDLLSRNRKLELNFKQILSHKIRVAQELCLGLREDAAFEGSDIEIDALATNMVVLITYWLSYEYVRNPRKYTEQEAMSDSLVRGCYQVLVLICPYLRGDTNVQFKLKMQEYLLKLKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GW10</accession>
    <name>A0A2S9GW10_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="12">TonB family C-terminal domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">S2091_3402</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
            <orientation evidence="1">Periplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TonB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000018">
        <property type="protein sequence ID" value="PRC91846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91846">
        <property type="protein sequence ID" value="PRC91846"/>
        <property type="gene ID" value="S2091_3402"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006260">
        <property type="entry name" value="TonB/TolA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037682">
        <property type="entry name" value="TonB_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03544">
        <property type="entry name" value="TonB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01352">
        <property type="entry name" value="tonB_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015590615" evidence="10">
        <location>
            <begin position="26"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_C" evidence="11">
        <location>
            <begin position="186"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="41"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF03544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PRC91846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="265" mass="30077" checksum="932F015B336A1961" modified="2018-07-18" version="1">MTKRWIYKSLFALVTYTSISLHSHAMSVDFFAETINNINDSSQTSPEQLSTTNEIQQNKSSQNQEHEGLNIELQDNINEKLVLLKECKKSNQHVLSYFSILINHINKLDSKYSQPALEQTRLEKLFQTYKSLGGLENSAKDVRALPDPCEPVLTEIRANVDMQLNSQRAERPKFSFPVVDFKICNKPDYPPISVRNEEHGSIRLAFLIETDGSISSSFQMSSTGSPFLDAAAFNALSKCQFKPGIYDGKPIRSWSIVDYNWVMPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GW68</accession>
    <name>A0A2S9GW68_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 6">ATP phosphoribosyltransferase regulatory subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">hisZ</name>
        <name evidence="8" type="ORF">S2091_3462</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 6">Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 6">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 1/9.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Heteromultimer composed of HisG and HisZ subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="6">This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 6">Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000018">
        <property type="protein sequence ID" value="PRC91906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91906">
        <property type="protein sequence ID" value="PRC91906"/>
        <property type="gene ID" value="S2091_3462"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00006"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00773">
        <property type="entry name" value="HisRS-like_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00125">
        <property type="entry name" value="HisZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041715">
        <property type="entry name" value="HisRS-like_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004516">
        <property type="entry name" value="HisRS/HisZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004517">
        <property type="entry name" value="HisZ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43707">
        <property type="entry name" value="PTHR43707"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13393">
        <property type="entry name" value="tRNA-synt_His"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001549">
        <property type="entry name" value="His-tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00443">
        <property type="entry name" value="hisZ_biosyn_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="tRNA-synt_His" evidence="7">
        <location>
            <begin position="10"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005539"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00025246"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF13393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC91906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="384" mass="42558" checksum="ED72A55B5C5CD9A7" modified="2018-07-18" version="1">MPNWLLPENIADVLPSEARKIEELRRRLLDLFRLYGYELVMPPMLEYLESLLCGAGQDLDLRTFKLVDQLSGRTLGVRADMTTQVARIDAHLLNRNSVTRLCYAGSVLHTRPSGLHATREPLQIGAEIYGHAGLEADVEIQELLLASMSLAGMTKVRLDLCHVGVLRAILAQDPLAKQSELALYALLETKDIPGLKEISTDFLEQTRNALLALPNLYGDVNVLEQARQILPKLPEINTALDELAFLVSLIPSDIDAEVTIDLADLRGLHYHSGVTFAAYVHGLPNAVARGGRYDHVGESFGRARPATGFSLDLRELARLLPGAERKDAIMAPWGLEVGLREKIAQLRKQGEIVIQSLPGHKNELDEFDCNRAVVFENGNWILKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GW82</accession>
    <name>A0A2S9GW82_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3327</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000017">
        <property type="protein sequence ID" value="PRC91985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91985">
        <property type="protein sequence ID" value="PRC91985"/>
        <property type="gene ID" value="S2091_3327"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010727">
        <property type="entry name" value="DUF1302"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06980">
        <property type="entry name" value="DUF1302"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015393048" evidence="1">
        <location>
            <begin position="25"/>
            <end position="605"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="605" mass="65498" checksum="C7CC09C0908B3919" modified="2018-07-18" version="1">MKKSILKLVGVTVCGAVTYLPVHAENYDTGIGDLQAAWVSNITGGIGMRTKSPSCTLTGDPNANGCGASANVAGWANGDNGDLNYKKDQLYTAYSSLTSELYLTSREQGFKFLMRATGLYDFAADDTQRTPLSTDAKAQSVHSIVLLDLWAQKDFQLADQSAHVRLGNQVINWGESQYALGGINATNSLDLQKLDLPGTLLKQALLPAPMLSFVSSLPGGWSTEAYVQWGWNGDKFPPVGTFWSTSNGLGRGAVPFTSNTTNYNLGGLNAGSIAGANSNNSQYYDSVNQNLVNGQYSGAPYNSIGYQPITNNPGNNTQGGVKLAYKPSGSDVSYAFYYENYTDKMPNATYLASGATEYSYVKDRSLFGVSANFQSGQWAFGTELSYRPHDAVSMTGCFIQGGPADYNTNALAGANCQGWKDFSKYEFIFDAQWQQTRGDPFLSLVNADTGIFSAELAVIDYPDVNANTQYTRTVAGQKIYQLVDAGYGASLVNNQALGYQIYQGVGTSVSSGLVLDYNVTYDNSVIKGWQVTTGLTFYDSFKGVTPTLYENYAHGYKSANFYMLFNQNPAVWQAGLNYTAFFGGNSTTNAYSDRNNIGVFVTRNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWA6</accession>
    <name>A0A2S9GWA6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Growth regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3357</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000017">
        <property type="protein sequence ID" value="PRC92015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92015">
        <property type="protein sequence ID" value="PRC92015"/>
        <property type="gene ID" value="S2091_3357"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007159">
        <property type="entry name" value="SpoVT-AbrB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037914">
        <property type="entry name" value="SpoVT-AbrB_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04014">
        <property type="entry name" value="MazE_antitoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00966">
        <property type="entry name" value="SpoVT_AbrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89447">
        <property type="entry name" value="SSF89447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SpoVT-AbrB" evidence="1">
        <location>
            <begin position="6"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="82" mass="9080" checksum="1C9017A6A4B5910E" modified="2018-07-18" version="1">MLQTLRRAGGSLVMTVPKAFIEQNNLQDGSQVELSLEGHRMTIDAPTKRRYKLDALLAEMPAGKLPMVEGWDDMKPAGLEVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWD0</accession>
    <name>A0A2S9GWD0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Patatin phospholipase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_3308</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000017">
        <property type="protein sequence ID" value="PRC91966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91966">
        <property type="protein sequence ID" value="PRC91966"/>
        <property type="gene ID" value="S2091_3308"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021095">
        <property type="entry name" value="DUF3734"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002641">
        <property type="entry name" value="PNPLA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12536">
        <property type="entry name" value="DUF3734"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01734">
        <property type="entry name" value="Patatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="SSF52151"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51635">
        <property type="entry name" value="PNPLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="1 2" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PNPLA" evidence="3">
        <location>
            <begin position="27"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXGXXG" evidence="2">
        <location>
            <begin position="31"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXSXG" evidence="2">
        <location>
            <begin position="58"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="DGA/G" evidence="2">
        <location>
            <begin position="217"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="2">
        <location>
            <position position="60"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC91966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="381" mass="41632" checksum="C8EB48413A6C1A6B" modified="2018-07-18" version="1">MTNRHAEKPSLRAGATNNLQLPGRVVLVLQGGGALGAYQVGVYEALHAAGIEPEWVIGTSIGAINGALIAGNKPADRMEKLLAFWEKIEQQSIATRFDPFGVSSLFSNITTVLNGIPSFFKPNPAALLGNKVKLGVEKASYYSTEPLARTLCELVDFGQINGMGKTRLTVGAVNVNSGMMRYFDSSNTHIDAKHIMASGALPPAFGAIRIEDAPYWDGGIYSNTPIEAVLDDNPRRNSLIFAVNVWHQSGPEPESIADVLARQKDIQFASRADSHIEKQKQIHRLRHVIRELGKQLPASKQNEACVKELTAWGCGTTMHVAHLVAPRLDDEDQSKDIDFSFTGVNARRAAGYADTLRMIERAPWREGNDSIEGIIEYRSCP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWP1</accession>
    <name>A0A2S9GWP1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3050</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92134">
        <property type="protein sequence ID" value="PRC92134"/>
        <property type="gene ID" value="S2091_3050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="163" mass="18365" checksum="70DE941E6D734A90" modified="2018-07-18" version="1">MKLIATKQGKTEKYDVLRCVRKNGTETSTKMPRQGQLPHDLIHYVVETALGYEHGFLGLIAKGADLAFAMEQTHDIQNQQIADQATHAEALVESLQAQMWSGMFDNEQFLAGLEGACSMRNRAVPDLSKINPERDLYEVVLALAQRWLQVPFYASLELDMQNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWR3</accession>
    <name>A0A2S9GWR3_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 11">Lipid-A-disaccharide synthase</fullName>
            <ecNumber evidence="3 11">2.4.1.182</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">lpxB</name>
        <name evidence="12" type="ORF">S2091_3075</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 11">Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 11">
            <text>a lipid X + a UDP-2-N,3-O-bis[(3R)-3-hydroxyacyl]-alpha-D-glucosamine = a lipid A disaccharide + H(+) + UDP</text>
            <dbReference type="Rhea" id="RHEA:67828"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:137748"/>
            <dbReference type="ChEBI" id="CHEBI:176338"/>
            <dbReference type="ChEBI" id="CHEBI:176343"/>
            <dbReference type="EC" id="2.4.1.182"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="11">Bacterial outer membrane biogenesis; LPS lipid A biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the LpxB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.182" evidence="3 11"/>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92159">
        <property type="protein sequence ID" value="PRC92159"/>
        <property type="gene ID" value="S2091_3075"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00973"/>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008915">
        <property type="term" value="F:lipid-A-disaccharide synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009245">
        <property type="term" value="P:lipid A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00392">
        <property type="entry name" value="LpxB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003835">
        <property type="entry name" value="Glyco_trans_19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30372">
        <property type="entry name" value="PTHR30372"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02684">
        <property type="entry name" value="LpxB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00215">
        <property type="entry name" value="lpxB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6 11" id="KW-0441">Lipid A biosynthesis</keyword>
    <keyword evidence="5 11" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="9 11" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 11" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00029342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PRC92159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="380" mass="42109" checksum="04F83BEE355F6992" modified="2018-07-18" version="1">MSANIAVVAGETSGDLLASRLLSGLRPQLPDAHMHGIGGKHMAEYGFVSDYPMETLSVRGLFEVLMHYREIKAVQTNLSTQLLAERPDVFIGVDAPDFNFTVEQRLKEAGIPTVHFIGPSIWAWRAGRIKKIIKSVSHMLVIFPFESEIYQAANIPVTYVGHPLAEVLPLEPDMMAARKELGLPLDANVVTIMPGSRLSEINYNTAAFIGAAKLLAERDPSIRFVVPMAGSKQRDAYIQQVVQAKLMDVPVLLIDGRSHTAITAANSVLVASGTATLEVALLKKPMVIAYKQIWASWQIMRHMGYQPWVGLPNILAREFLVPEFLQDAATPLALADALWKQLHDDKLVTRLKQRFLEMHHSLLRDSARESAQAILQVINK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWR4</accession>
    <name>A0A2S9GWR4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3079</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92163">
        <property type="protein sequence ID" value="PRC92163"/>
        <property type="gene ID" value="S2091_3079"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021847">
        <property type="entry name" value="DUF3443"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11925">
        <property type="entry name" value="DUF3443"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015618535" evidence="1">
        <location>
            <begin position="27"/>
            <end position="439"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="439" mass="44212" checksum="91BF08A840EAE045" modified="2018-07-18" version="1">MKNTRNLTKLFFAAVVLLGCMNTSWAQSTAMGCGTVTSTGTGNTTPLVIDGFPCAAGGTAGAVNAAMEPYVSVKICAPGSTTNCQIIDHVIVDTGSTGLRIAATALSSKLQPGVSGGLPLVAGSSSGTKLTECETYVDSYVYGPVVNADVYIAGELVKSTTMQVFGSSSYTVPKTCSSQGGTQTDTTQSFGGNGLIGVSFDLADNYPLYFNCKTATGSSCSANTAYAGMPSTVSQFATDNNGVVLSLPAVGASGSTTAVVGTLMFGVSTQSNNVPAAATLPIVNLGGNTSLSGTFNTEVGGTWYSAYIDSGTDVIYFNDTANKNLKACPTSGNFDGWYCPTTVQSVPFSMANTGSTTAKGTLTYSVANASVIAGSKVIAYNNVAGSDGSSATTNSSVGFGLSTFLGHNMYILFNGMTAPGTGLGGNSSTTVTGPINGID</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWS2</accession>
    <name>A0A2S9GWS2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="8">TM2 domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_3091</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the N-Me-Phe pilin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92175">
        <property type="protein sequence ID" value="PRC92175"/>
        <property type="gene ID" value="S2091_3091"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009289">
        <property type="term" value="C:pilus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007155">
        <property type="term" value="P:cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001082">
        <property type="entry name" value="Pilin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007829">
        <property type="entry name" value="TM2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00114">
        <property type="entry name" value="Pilin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05154">
        <property type="entry name" value="TM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="38"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="63"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="109"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="TM2" evidence="7">
        <location>
            <begin position="34"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF05154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC92175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="244" mass="26259" checksum="1D61F46639FD35A4" modified="2018-07-18" version="1">MSDMVFCRGCGKEIHVTAPTCPGCGAPQRVAKAGKSKVVAAVLALFLGALGIHRFYLGQWWGVFYLLFCWTGIPSLISFIETIVFLCTSDKTWDDKHNGGIPSNGGSTAAVVVTVFVCLFGGVFVIGILAAIAIPQYQTYTIKAKMAEVESEGQKITSSFTRYMQDNKSIPANINVLGVDVSNKFISEVEINQVNGVVSLTLTGSVPINGKHFLLIPKVDADKKLIWGCGSEDLAVAYIPTKCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GX03</accession>
    <name>A0A2S9GX03_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Addiction module antitoxin, RelB/DinJ family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2908</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RelB/DinJ antitoxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92249">
        <property type="protein sequence ID" value="PRC92249"/>
        <property type="gene ID" value="S2091_2908"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000987">
        <property type="term" value="F:cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015643">
        <property type="term" value="F:toxic substance binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044010">
        <property type="term" value="P:single-species biofilm formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1220.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013321">
        <property type="entry name" value="Arc_rbn_hlx_hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026262">
        <property type="entry name" value="DinJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007337">
        <property type="entry name" value="RelB/DinJ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38781">
        <property type="entry name" value="PTHR38781"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04221">
        <property type="entry name" value="RelB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003108">
        <property type="entry name" value="DinJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02384">
        <property type="entry name" value="RelB_DinJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="87" mass="9208" checksum="A1FC31E67E144527" modified="2018-07-18" version="1">MAANQLVQARIDGAIKEEAAAVLAAMGLTISDAVRLLLTKIAYEHALPFDPLIPNATTVAAMREARAGNLPRASSIDELKKSLHADD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GX29</accession>
    <name>A0A2S9GX29_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 10">3-oxoacyl-[acyl-carrier-protein] synthase 2</fullName>
            <ecNumber evidence="3 10">2.3.1.179</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">S2091_3132</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>(9Z)-hexadecenoyl-[ACP] + H(+) + malonyl-[ACP] = 3-oxo-(11Z)-octadecenoyl-[ACP] + CO2 + holo-[ACP]</text>
            <dbReference type="Rhea" id="RHEA:55040"/>
            <dbReference type="Rhea" id="RHEA-COMP:9623"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="Rhea" id="RHEA-COMP:10800"/>
            <dbReference type="Rhea" id="RHEA-COMP:14074"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78449"/>
            <dbReference type="ChEBI" id="CHEBI:83989"/>
            <dbReference type="ChEBI" id="CHEBI:138538"/>
            <dbReference type="EC" id="2.3.1.179"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>a fatty acyl-[ACP] + H(+) + malonyl-[ACP] = a 3-oxoacyl-[ACP] + CO2 + holo-[ACP]</text>
            <dbReference type="Rhea" id="RHEA:22836"/>
            <dbReference type="Rhea" id="RHEA-COMP:9623"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="Rhea" id="RHEA-COMP:9916"/>
            <dbReference type="Rhea" id="RHEA-COMP:14125"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78449"/>
            <dbReference type="ChEBI" id="CHEBI:78776"/>
            <dbReference type="ChEBI" id="CHEBI:138651"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 10">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 10 12">Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.179" evidence="3 10"/>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92216">
        <property type="protein sequence ID" value="PRC92216"/>
        <property type="gene ID" value="S2091_3132"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00094"/>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00834">
        <property type="entry name" value="KAS_I_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017568">
        <property type="entry name" value="3-oxoacyl-ACP_synth-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000794">
        <property type="entry name" value="Beta-ketoacyl_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018201">
        <property type="entry name" value="Ketoacyl_synth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11712">
        <property type="entry name" value="PTHR11712"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000447">
        <property type="entry name" value="KAS_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03150">
        <property type="entry name" value="fabF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00606">
        <property type="entry name" value="B_KETOACYL_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="8 10" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="5 10" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PKS_KS" evidence="13">
        <location>
            <begin position="9"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR000447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000447-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="PRC92216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="415" mass="43671" checksum="DEAC1C4B7A5FF52E" modified="2018-07-18" version="1">MSRSQHRRVVVTGMGCVSPVGNNLSDTWSAVTSGTSGIATITKFDPSPFTTHFGGEVKGFNIEDYIPAKEARHMDTFIHFGLAAGMQAMQDSGLVVTEQNAERIGVMVGSGIGGLPLIEETHTEYTNRGARRISPFFVPASIINMISGHLSIKYGLKGPNLSIVTACSTGLHCIGAAARMIEYGDADVMVAGGAESTMSPLGLGGFASARALSSRNDDPATASRPWDKDRDGFVLGEGAGVMVLEEYEHAKARGARIYAEVLGFGMSADAYHMTAPLEDGDGAKRCMNAALKSAQINPDQVDYINAHGTSTPLGDLAETVGIKRTFGDHAKKLVVNSTKSMTGHLLGGAGGLESVFTVLAVHHQLSPPTINIFNQDPACDLDYCANTARAMPINIAVKNSFGFGGTNGTLIFGKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GX64</accession>
    <name>A0A2S9GX64_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Phosphoribosyl pyrophosphate synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_2971</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the ribose-phosphate pyrophosphokinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92312">
        <property type="protein sequence ID" value="PRC92312"/>
        <property type="gene ID" value="S2091_2971"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004749">
        <property type="term" value="F:ribose phosphate diphosphokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009165">
        <property type="term" value="P:nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029099">
        <property type="entry name" value="Pribosyltran_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRibTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005946">
        <property type="entry name" value="Rib-P_diPkinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10210">
        <property type="entry name" value="PTHR10210"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00156">
        <property type="entry name" value="Pribosyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13793">
        <property type="entry name" value="Pribosyltran_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01251">
        <property type="entry name" value="ribP_PPkin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="1 3" id="KW-0545">Nucleotide biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pribosyltran_N" evidence="5">
        <location>
            <begin position="28"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="domain" description="Pribosyltran" evidence="4">
        <location>
            <begin position="145"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00029942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF13793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC92312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="287" mass="31915" checksum="CDC83B26E20CF9D4" modified="2018-07-18" version="1">MDSHVTTKNRYFLPNPQQAGDLFKLFQFGSGENHLQILAPSSSHVEIMFRYSGDQSLIQLLLLTDALRRQGATNIDLFIPYFPGARQDRVCNQGEALSVKVYADLINQQHYQKVCVFDPHSDVVVALLNNVYCVKNHQFIREVVSEIGANLILISPDAGSNKKIFELSSQLGGLPVVRADKIRDVRNGAIIGTEVFCDDLSGKTAVIVDDICAGGRTFIELAKKLKAKNCEKIVLVVSHYEDTADEKKLAESGIDAIYTTNSLQDLVATELLNVKNIWRFMPTQGEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GX99</accession>
    <name>A0A2S9GX99_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">FGE-sulfatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2990</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92331">
        <property type="protein sequence ID" value="PRC92331"/>
        <property type="gene ID" value="S2091_2990"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005532">
        <property type="entry name" value="SUMF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042095">
        <property type="entry name" value="SUMF_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03781">
        <property type="entry name" value="FGE-sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="SSF56436"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FGE-sulfatase" evidence="1">
        <location>
            <begin position="4"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="248" mass="28907" checksum="367A99B2BBE52E95" modified="2018-07-18" version="1">MTINMVKISPIAFKMGSDKYKNERPVRQVNLSGYYIDLFPVTNTRYKKFIESQGYKNRQYWTDDGWDFIHSKKISKPLYWCNTNWNQPNQPVTGVSWWEALAFSRFENKTLPTEAQWEYMASGGVNIYPWGDDTPTLLKANYAEGCEPTDLERRSTNVDHFLHSRSHCGCWDVAGNVGEWCLDNHSENYGWDIEKKNPIFLTKETKAHIVRGGSGLHDDEYLRSTSRDYYAPTIRDNIVGFRCVINME</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXL9</accession>
    <name>A0A2S9GXL9_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Phosphoribosylaminoimidazole-succinocarboxamide synthase</fullName>
            <ecNumber evidence="8">6.3.2.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">SAICAR synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">purC</name>
        <name evidence="10" type="ORF">S2091_2781</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + ATP + L-aspartate = (2S)-2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate + ADP + 2 H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:22628"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58443"/>
            <dbReference type="ChEBI" id="CHEBI:77657"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.6"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the SAICAR synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.6" evidence="8"/>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92406">
        <property type="protein sequence ID" value="PRC92406"/>
        <property type="gene ID" value="S2091_2781"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00131"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004639">
        <property type="term" value="F:phosphoribosylaminoimidazolesuccinocarboxamide synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00137">
        <property type="entry name" value="SAICAR_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028923">
        <property type="entry name" value="SAICAR_synt/ADE2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001636">
        <property type="entry name" value="SAICAR_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018236">
        <property type="entry name" value="SAICAR_synthetase_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01259">
        <property type="entry name" value="SAICAR_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00081">
        <property type="entry name" value="purC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01058">
        <property type="entry name" value="SAICAR_SYNTHETASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 8" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 8" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SAICAR_synt" evidence="9">
        <location>
            <begin position="15"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC92406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="293" mass="32409" checksum="178B4EE4E84A4A42" modified="2018-07-18" version="1">MSGILETNLKSLPFLHRGKVRDIYAVGEDHLLVVQTDRLSAFDVILDDAIPDKGKVLTTMSNFWFKKFGHLMPNHMTDIDPLTLVTADERAQVEGRAIVVKKFKPLAIEAIVRGYIIGSGWKDYQKTGMVCGHVLPAGLKEGQKLPEVLFTPSTKAPMGQHDENISFAEAEAIVGADIAAKVRDLAIQLYTEAAEFAATKGIIIADTKFEFGLDAANNIYLIDEILTPDSSRFWPAASYQVGISPPSFDKQFVRDWLETQPWNKKAPAPRLPIEVAQQTADKYAEALRLLTVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXN3</accession>
    <name>A0A2S9GXN3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2857</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92482">
        <property type="protein sequence ID" value="PRC92482"/>
        <property type="gene ID" value="S2091_2857"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="110" mass="12444" checksum="5EB51D1776917523" modified="2018-07-18" version="1">MMYSTTADDEVQVSHATNPFPIDLDFHKTLDGLPSTSFIPFSVSRLSSARLVWRNSAIARDVDLSSFDYCLPHVADRDTVYRNEWRTFNAERYGGQRIVNNGGGVRCAIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXQ1</accession>
    <name>A0A2S9GXQ1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phosphoesterase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2863</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92488">
        <property type="protein sequence ID" value="PRC92488"/>
        <property type="gene ID" value="S2091_2863"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007312">
        <property type="entry name" value="Phosphoesterase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31956">
        <property type="entry name" value="PTHR31956"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04185">
        <property type="entry name" value="Phosphoesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015630998" evidence="2">
        <location>
            <begin position="25"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="173"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="175"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="426" mass="44739" checksum="50A602DB51897897" modified="2018-07-18" version="1">MYSFKNLTSLVAGFIILCGVGLVAGCNTQSTPVTTTAQNSIKHVFVITLENKNFSSTFGNSTQDTYLQGTLVPMGALLTQYYGTGHVSLDNYVSMISGQPSSLATQTDCAEYQDFSLSSTDSNGIATGTGCVYPASVKTLPDLLTAANLSWRGYMEDMGNDPTRESAACGHPALNTRDLTQSPEAPTTAVPNGDQYATRHNPFMYFHTIIDSPSCATNVVALPQLKKDLAAASSTPNFVFITPNLCHDGHDGDGTGTAGKGCVNGEPGGLTSIDAFLKEWVPLIMASPAYQQDGMIVINFDEGAPPTPAVTMVSGIPTLTLTYPGAPCCGQQTGPNVTRPYITDYPASAATGGMPVQLSYAGIGGDQTGAVLISPFIKPGTVSNTPYNHYSLLKSLQDIYSVTPYLGYASQPGLVGFGSDVYVKSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXW7</accession>
    <name>A0A2S9GXW7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Dehydrogenases with different specificities (Related to short-chain alcohol dehydrogenases)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2617</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92562">
        <property type="protein sequence ID" value="PRC92562"/>
        <property type="gene ID" value="S2091_2617"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="257" mass="27081" checksum="B81B54A1B063DA61" modified="2018-07-18" version="1">MKRNVLITGACGGIGRVLCQRFIAAGDFVYAQDKNAAQLSDLIAELGAQQSAAVLADLTNAQNLQAELANAVAQHGDVDVVVANAGAAEALTLATTTEASWKSDIDLNLNGTFHTVEAVRSAMQKNRKGNIVIIGSVNGITSFGHPAYSVAKAGLISYTKALAMEFGKFGIRANIVCPGTVKTQAWQARAEKNPQIFDELKKWYPLGDFATPDDIADAVLFLASDAARVITGVMLPVDGGLMAGNRVFAAELTQEDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXZ1</accession>
    <name>A0A2S9GXZ1_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_2638</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92583">
        <property type="protein sequence ID" value="PRC92583"/>
        <property type="gene ID" value="S2091_2638"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004673">
        <property type="term" value="F:protein histidine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013655">
        <property type="entry name" value="PAS_fold_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08447">
        <property type="entry name" value="PAS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PAC" evidence="4">
        <location>
            <begin position="90"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="3">
        <location>
            <begin position="187"/>
            <end position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC92583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="426" mass="47715" checksum="FE4AF9B8716501CA" modified="2018-07-18" version="1">MKKVHKDAEPDLSRSTQLLASALEWSHTGAWDIDLVDKTANRTREHDLIFGYDALLPEWTYDMFIEHVLPEDRADVNCLFQKAIEEQTVWRFECRIRRADGVVRWIFAAGGHQCAPDGVMRRMAGIVQDITERKQAEMAIHTLNATLERRVAERTAELEATLESLRLSQQELARSETKAMLSMLVASVSHELNSPIGNSVLAATMLSTLTQKMRESIENGNIKRSDLNTMLVDIETGTSLIERNLKRAEDLLNSLRQVAADQASEQRRKFDLAHTIKEIIDTLSPSLKRQKHRIEMNIPDGIMMDSEPGPLGQIVINIINNAYLHAFENRTDCVLTIDADIVDDWVTLRFADNGVGIPDENLKKLFQIFYSTKIGNGGTGLGMAIVQNLVTKTLGGDIAVQSNVGVGTRFDIRLPMVLPEATSKVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GY00</accession>
    <name>A0A2S9GY00_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2635</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92580">
        <property type="protein sequence ID" value="PRC92580"/>
        <property type="gene ID" value="S2091_2635"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021847">
        <property type="entry name" value="DUF3443"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11925">
        <property type="entry name" value="DUF3443"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015535737" evidence="2">
        <location>
            <begin position="27"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="471" mass="47167" checksum="A70CB728781EFC0D" modified="2018-07-18" version="1">MKVSQLARIHALITISMFSATMLLSACGGGGSSNNGNSSPTATTPPPVVTPTPTPPTPPTPPTAGTPAMGCGNVTSTGTGNTTQIVVDGFPCAAGGGVGQINQVDQPYVSVKICAPGSTTNCQIIDHIILDTGSTGLHIMASALSPSLQPGATGLPLMAGSAGTTLTECEVYVTSYVYGPLATADVYIAGEAVKNLPMQVIAQPGYTTPTACSKGGGTATQSTASFGGNGIIGVSFASVDSGLFFDCNNSASGTCVNDNSFVGLPHPVQKFATDNNGISITMPAISTSGVASAVGTLTFGISTQTNNVPSTSTIPLVLGFNTTNGTDGDFQTLINGYWQLTYMDSGTTEDTLLDAALPACTSASGASGLYCPTSVTNVSIGLADFNTSTVKGTLTTPVGNASTLGASTNLAAFNDLIYTNGTAASAQPQVIGFSNFFGHTMWVLFENSSAQGTGLGGTANTKVTGPMYGVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYA5</accession>
    <name>A0A2S9GYA5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2754</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92699">
        <property type="protein sequence ID" value="PRC92699"/>
        <property type="gene ID" value="S2091_2754"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="289" mass="32131" checksum="41B58E103F0952DA" modified="2018-07-18" version="1">MLNPLRNVVSRLCGARLHLGITTKGIALARTSGGWNKKISLLADQALSSDQLKNQCDALLTLPSCTTLPLLVTLSDEWGHLFMVTPPHNAEHYSDLVAAATMRFQALYGKVSADWQINADWQVDRPFLACAYPRSLLNTLQQIAQERRMPLLSVRPYFVTVWNQWSSKLKPNNWFGVVQDATLTLGITSELHPQHLIGIRTIAIPTHGQNRDWIAEQLTRTALQHNVTAPKQIQVVGNQHHYWGDKAATPVVDQLVLNLVEQQNQSSTVASLPQILSPARQLIYCGVGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYI9</accession>
    <name>A0A2S9GYI9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Major Facilitator Superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_2522</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92792">
        <property type="protein sequence ID" value="PRC92792"/>
        <property type="gene ID" value="S2091_2522"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="161"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="285"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="319"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="349"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="374"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="407"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="435"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="483"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="524"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="548"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="575"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="623"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="647"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="7">
        <location>
            <begin position="186"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="281"/>
            <end position="670"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC92792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="678" mass="74054" checksum="8AA6F0D891789A1C" modified="2018-07-18" version="1">MKKLQIRLVSFVALIFVLSALLMSWLSLRHFEQGLPPEMARTVTTISYSASAVLERAYENGVPLEKMIGVEEFLSEIRKENPSISYLLLNDNKGQVLYQSGVNNKAPELRSVIATSNSDVTTNLVGAYFNTSVPLIFNHYRVGTLQLGQQSALVEQQLKEIAYDVLTVLVVASLIAIELLRFTLSFVIATPVEVMRDFLARVRAGDFTYYLPFDRLGGIGQLSANFNHIVANINERFHALQQYISNNGDAGSVQVKQALSGFQFHAPGERRTLFAAALDHIRWPFFLLIFADSLSLSFFPVFVGQFYSPALGLSKNIVIGLPISIFMFTWALSMPLAGMWSDRVGYRKAFLVGASVTTVGLILTAGAQTLYDLLLWRSITALGYGLVFITAQSYVTNNTPPKQRTRGMAVFLSSFFAGSLSGSAIGGILSDRLGYSPTILLSAVLSIASGLFVMRFIHSAPSTAPKKKLGFNDFKRLLGNKKFSAITFLAAIPAKIALTGFLYYSVPLYLKLQGNNQSTTGRVMMAYGLAIIILSPSIAKLADRIGNLRWFVTIGGYSAALAMFVIYYFDNMAGVLVSITLLGIAHAIGVSPQLALINDFCKEVVQEVGAGTASGIFRLTERLGNVFGPIIAALFISQFGFKGAFLGIGIISLICITSFTVLLFFFDRHQTRAVAIPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYN5</accession>
    <name>A0A2S9GYN5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltransferase domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2567</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92837">
        <property type="protein sequence ID" value="PRC92837"/>
        <property type="gene ID" value="S2091_2567"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_25" evidence="1">
        <location>
            <begin position="47"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="215" mass="24473" checksum="2A4791C28146C002" modified="2018-07-18" version="1">MNMNTNLHNYYAQRAAHYEEIYQFPERQTELIGIATQLQHLLKDKKVLEVACGTGYWTELYAAIASQVVATDVNAEMLAIARAKQMPAERVSFQEADAFALPDGDFNACVAGFWWSHVKRSEQSAFLEGLQKTCGSGSVFVMFDNCYVEGSSTPIARTDMEGNTYQIRRLPDDSRHEVIKNFPTDSTLRKKLTQHARDIRVVRGTYYWMLTGVLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYQ6</accession>
    <name>A0A2S9GYQ6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2573</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92843">
        <property type="protein sequence ID" value="PRC92843"/>
        <property type="gene ID" value="S2091_2573"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="108" mass="12233" checksum="6FF6F875EC9B9004" modified="2018-07-18" version="1">MQTQPGQLLNALGNTLNWHGDGYTVSGQARRPTELALLQGIRHSAMLAFVDEEPELISRWIWLERAQPQLNTDLEWRLLDSLFQIDPAAGLLRVGEDGQFFQANKLSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYS2</accession>
    <name>A0A2S9GYS2_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Probable membrane transporter protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_2536</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92806">
        <property type="protein sequence ID" value="PRC92806"/>
        <property type="gene ID" value="S2091_2536"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002781">
        <property type="entry name" value="TM_pro_TauE-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01925">
        <property type="entry name" value="TauE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="78"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="106"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="146"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="235"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC92806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="254" mass="26288" checksum="B3E35D0C69A544BC" modified="2018-07-18" version="1">MIIANQPLPVLLLIALAGLYAGMQNALAGGGSFITFPALLLAGLNPLAANMSSTIALFPSQITTAIAGRKMVSGVGHLSFRSLFIVSLIGGVLGALLLLSTPVSIFTNLVPWLVLFATAAFAWGSFGYQPHSTATARQLPNSVLLLIQGVIAIYGGYFGGGIGFLMLAALTVAGQQVRAASATKNALAMTMNASAVAIFAFSPMINWAAVVALGLGGVLGGLIGSWLIHRLPERLLRGFVVLVGVVLTVWLFLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYT4</accession>
    <name>A0A2S9GYT4_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex</fullName>
            <ecNumber evidence="4">2.3.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_2304</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 4">
            <name>(R)-lipoate</name>
            <dbReference type="ChEBI" id="CHEBI:83088"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the 2-oxoacid dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="4"/>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92887">
        <property type="protein sequence ID" value="PRC92887"/>
        <property type="gene ID" value="S2091_2304"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.320.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003016">
        <property type="entry name" value="2-oxoA_DH_lipoyl-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001078">
        <property type="entry name" value="2-oxoacid_DH_actylTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036625">
        <property type="entry name" value="E3-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004167">
        <property type="entry name" value="PSBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00198">
        <property type="entry name" value="2-oxoacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02817">
        <property type="entry name" value="E3_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47005">
        <property type="entry name" value="SSF47005"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="SSF51230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00189">
        <property type="entry name" value="LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51826">
        <property type="entry name" value="PSBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3 4" id="KW-0450">Lipoyl</keyword>
    <keyword evidence="7" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="5">
        <location>
            <begin position="3"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="domain" description="Peripheral subunit-binding (PSBD)" evidence="6">
        <location>
            <begin position="146"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001938"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC92887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="433" mass="46275" checksum="C7318D2475863EC6" modified="2018-07-18" version="1">MGIHVIKMPDIGEGIAEVEVVVWRVQPGDVVVEDQILADVMTDKATIEIPSSVAGTVLTLGGKAGEFMAVGAELIRIEIEGKGNVRENAPALPAAVAVAEKVEKTAAAPLAAVAPMAAAASQPAPANKPGKVQSISVARPAGEKPIASPAVRRRAWDLGVELQFVHGSAAGGRIQQQDLDDFVARGPQQAAGSVGARYHQLHTEEAVPVIGLRRKIAQKMQDAKRRIPHFTYVEEIDMTELEALRVNLNNKWGKERGRLTILPFLMRAMVLALRDFPQINARFDDEAGIVTRFGAVHIGIATQTDNGLIVPVVRHAESLDFWASAAEVTRQAEGARSGKAAREDLSGSTITLTSLGTLGGIVSTPVINHPEVAIVGVNRMVLRPVIRGGAVVARQMMNLSSSFDHRVIDGMHAAEFIQAIRGFLECPAMLFTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYW8</accession>
    <name>A0A2S9GYW8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2339</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92922">
        <property type="protein sequence ID" value="PRC92922"/>
        <property type="gene ID" value="S2091_2339"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="17"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="307" mass="33786" checksum="068C28A95964B237" modified="2018-07-18" version="1">MTTQPNNEATYRKPKPLITIVIAGAFLAAVILWVLSYWLRESVLPPASPQITNQAKDLPQSGRKWFSDFKNSPSISDGSKKFRDIAGYFNLNGLTVSQFVKTQYAAANKGDKDAAFNIYRAESICSRSTDAQRTLNLLPIETEKLILDSTKSYIKDAQPVCADLNISPKERLDYLRIAAKAGLAEAAIGFAIENPEGLNFSPEIQIDYSDPNVIQWQKDVVDYLTQPATQGNTKALGWLATMYEGGRLIPRNLQMALTYNLARAQILNENPNDNPVTASMLQNLPPDQVNAAEAAATALVNACCKQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYY1</accession>
    <name>A0A2S9GYY1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2338</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92921">
        <property type="protein sequence ID" value="PRC92921"/>
        <property type="gene ID" value="S2091_2338"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="39" mass="4352" checksum="9711CE11381F9713" modified="2018-07-18" version="1">MTNEANRAQSAQTSRPIDVQFNKNLIGQNLGKTVRDYAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZ49</accession>
    <name>A0A2S9GZ49_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ysc84 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2429</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC93012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93012">
        <property type="protein sequence ID" value="PRC93012"/>
        <property type="gene ID" value="S2091_2429"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007461">
        <property type="entry name" value="Ysc84_actin-binding"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04366">
        <property type="entry name" value="Ysc84"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015478667" description="Ysc84 domain-containing protein" evidence="1">
        <location>
            <begin position="31"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="domain" description="Ysc84" evidence="2">
        <location>
            <begin position="100"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="187" mass="20349" checksum="A94041A814C3DF89" modified="2018-07-18" version="1">MMHIQNRVHKFILVATTLFALTALVGQANATTAEELTKDSTQALHALYKTNPFAETIGKSAKAILVFPHILKAGLVFGGSYGEGVLFNSDKFNGYYNSVSASWGWQAGAESYGYVVFLMNDKAVNYLNKSHGWEFGVGPSIVVVNEGVAKNLSSTTLKNDAYAYIFDQQGLMVNLSIEGTKISPIKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZA6</accession>
    <name>A0A2S9GZA6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2151</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93065">
        <property type="protein sequence ID" value="PRC93065"/>
        <property type="gene ID" value="S2091_2151"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="63" mass="7186" checksum="87519EB7335FFDCB" modified="2018-07-18" version="1">MAKRAQPDRAALEIAHRQLCTDTPLDDMLASAALRPIVENVARRHMVRRAKFDVKKLQANDFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZC5</accession>
    <name>A0A2S9GZC5_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">UPF0125 protein S2091_2143</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2143</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the UPF0125 (RnfH) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93057">
        <property type="protein sequence ID" value="PRC93057"/>
        <property type="gene ID" value="S2091_2143"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.280">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00460">
        <property type="entry name" value="UPF0125_RnfH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016155">
        <property type="entry name" value="Mopterin_synth/thiamin_S_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005346">
        <property type="entry name" value="RnfH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037021">
        <property type="entry name" value="RnfH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37483">
        <property type="entry name" value="PTHR37483"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03658">
        <property type="entry name" value="Ub-RnfH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54285">
        <property type="entry name" value="SSF54285"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="103" mass="11617" checksum="742AB557A3261625" modified="2018-07-18" version="1">MRFVAGLKVFMGSDISVQVCFITPQLQFLRTLSVVPGTTIQQVVALSGILDEIPGIDINQLKVGIYSKIKNLDTVLKEHDRVEIYRPLQVDPMVARHRRANKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZE9</accession>
    <name>A0A2S9GZE9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2190</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93104">
        <property type="protein sequence ID" value="PRC93104"/>
        <property type="gene ID" value="S2091_2190"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="73"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="97" mass="10433" checksum="A646510187ACB405" modified="2018-07-18" version="1">MQDDYGNSLPRSPSPDEWASLCKWVGSLEDGLAENMKVCRRTEDNTAEIIIVFDSVKGAFKVLGWIGQIAKPVAAIISLGLATWGVVLAVKAGISQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZI5</accession>
    <name>A0A2S9GZI5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glutathione S-transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2235</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GST superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93149">
        <property type="protein sequence ID" value="PRC93149"/>
        <property type="gene ID" value="S2091_2235"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00043">
        <property type="entry name" value="GST_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02798">
        <property type="entry name" value="GST_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="SSF47616"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GST N-terminal" evidence="2">
        <location>
            <begin position="4"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="209" mass="23768" checksum="002D611CDDED528B" modified="2018-07-18" version="1">MSTVRELTFYHCPNTRSTGVLTLLEELAAEYHLYVLNMKEGEQRKPAFLAINPMGKVPTLKHGEAIITEQSAVYLYLADLYPDAGLAPKIDDPLRGPYLRWMVYYSSCFEPAIVDRSQKREPVPQSMSPYGDFETMYKTLTDQLSKGHYLLGDRFTAVDVLWGTALTWITKFQLVPLLPVVKTYIDRINARPAVAWARAKDAELIATFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZL4</accession>
    <name>A0A2S9GZL4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Oligoketide cyclase/lipid transport protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2142</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ribosome association toxin RatA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93056">
        <property type="protein sequence ID" value="PRC93056"/>
        <property type="gene ID" value="S2091_2142"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048039">
        <property type="term" value="F:ubiquinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045333">
        <property type="term" value="P:cellular respiration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006744">
        <property type="term" value="P:ubiquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07813">
        <property type="entry name" value="COQ10p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044996">
        <property type="entry name" value="COQ10-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005031">
        <property type="entry name" value="COQ10_START"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12901">
        <property type="entry name" value="PTHR12901"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03364">
        <property type="entry name" value="Polyketide_cyc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Polyketide_cyc" evidence="2">
        <location>
            <begin position="10"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="144" mass="16130" checksum="71B8B25D210415AE" modified="2018-07-18" version="1">MAVVQKSVLVGYSAEQMFALVDGVEEYPHFLPWCGGVQVLQRCETGLVATLNINFHGVHQSFTTENTNSAPTLMKMKLISGPFKHLDGTWHFKALRENACKIEFDLHYEFSSKILEHLIGPVFSKIANSFVDAFCSRAESVYGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZX9</accession>
    <name>A0A2S9GZX9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2262</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93176">
        <property type="protein sequence ID" value="PRC93176"/>
        <property type="gene ID" value="S2091_2262"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="115" mass="12985" checksum="1E296C442770718E" modified="2018-07-18" version="1">MRLIFILIFTILVAGCDFTFPGADEKFGQQNFVSAVSLIELHKTRNGVYPESLKDLKYLGDWDGIWLSAVRYEKAGKGYNLFVERGWAGKPHLEFPIGFKQGLGLQDSNVAWISK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H025</accession>
    <name>A0A2S9H025_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Acyl-CoA dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_2077</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93339">
        <property type="protein sequence ID" value="PRC93339"/>
        <property type="gene ID" value="S2091_2077"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003995">
        <property type="term" value="F:acyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006089">
        <property type="entry name" value="Acyl-CoA_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="SSF47203"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="SSF56645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00073">
        <property type="entry name" value="ACYL_COA_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA_dh_N" evidence="7">
        <location>
            <begin position="4"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_M" evidence="6">
        <location>
            <begin position="120"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_1" evidence="5">
        <location>
            <begin position="227"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC93339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="378" mass="41037" checksum="7E7C9419F4BA17B8" modified="2018-07-18" version="1">MILTSEHQMIREALREFSQERLAPNAARWDKEHHFPQEELTQLAQLGAFGVAVPEKWGGAGMDYLSLALVLEEIAAGDGGTSTVISVNNCPVCSIAMMYANDAQKEQWLRPLAQGSMLGAFCLTEPHVGSDAGALRTTAVKDGDEYVINGVKQFITSGKYADVAIVMAVTDKNAGKKGISAFWVSTKTPGYIVTRLEEKLGQHSSDTAQILFENCRIPAANLIGEEGQGYKIALSGLEGGRIGIASQSVGMARAAFEAALSYAKERESFGKPIFEHQAVQFKLADMATQIEAARQLIWHAASMKDAGMPCLKEAAMAKLFASEMAEKVCSDAIQIHGGYGYVTDFPVERIYRDVRVCQIYEGTSDIQKIIIGRSLAQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H048</accession>
    <name>A0A2S9H048_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="9">P pilus assembly protein chaperone PapD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_2089</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the periplasmic pilus chaperone family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93351">
        <property type="protein sequence ID" value="PRC93351"/>
        <property type="gene ID" value="S2091_2089"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030288">
        <property type="term" value="C:outer membrane-bounded periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061077">
        <property type="term" value="P:chaperone-mediated protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008962">
        <property type="entry name" value="PapD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036316">
        <property type="entry name" value="Pili_assmbl_chap_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001829">
        <property type="entry name" value="Pili_assmbl_chaperone_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016148">
        <property type="entry name" value="Pili_assmbl_chaperone_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018046">
        <property type="entry name" value="Pili_assmbl_chaperone_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016147">
        <property type="entry name" value="Pili_assmbl_chaperone_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02753">
        <property type="entry name" value="PapD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00345">
        <property type="entry name" value="PapD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00969">
        <property type="entry name" value="CHAPERONPILI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49354">
        <property type="entry name" value="SSF49354"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49584">
        <property type="entry name" value="SSF49584"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00635">
        <property type="entry name" value="PILI_CHAPERONE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4" id="KW-0574">Periplasm</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="domain" description="PapD_N" evidence="7">
        <location>
            <begin position="11"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="PapD_C" evidence="8">
        <location>
            <begin position="161"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC93351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="232" mass="25663" checksum="21D38C2663A168DB" modified="2018-07-18" version="1">MLFTAQTHANIVINGTRVIYDASDKEVTLRLNNATAQPSLVQVWLDSGDARSTPDNGKSPFIATPPIFRVDSNKGQTVRIVYTHEPLPQDKESVFWVNVLDVPPMPIAKKDDDANYMQLAIRSRIKLFFRPKNLPGTPVEAAAQIHWELVQKPDGLVLHATNDSAFHVSLGSTTLIFGDKSYEASTEMLAPGTSLDFPIKELKKIPTEPVKLNYLTVNDFGGIVEHSVSLLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H074</accession>
    <name>A0A2S9H074_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2091</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93353">
        <property type="protein sequence ID" value="PRC93353"/>
        <property type="gene ID" value="S2091_2091"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="53" mass="6219" checksum="76268B7A1271A5F5" modified="2018-07-18" version="1">MDIIRSTIMIIGNVCDVLLMLVVSFIYKISRVYLYFEVIPLYLTFVFGEIHES</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0B9</accession>
    <name>A0A2S9H0B9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Tellurite resistance protein and related permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_1804</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93417">
        <property type="protein sequence ID" value="PRC93417"/>
        <property type="gene ID" value="S2091_1804"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004695">
        <property type="entry name" value="SLAC1/Mae1/Ssu1/TehA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038665">
        <property type="entry name" value="Voltage-dep_anion_channel_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03595">
        <property type="entry name" value="SLAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="21"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="45"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="91"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="126"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="157"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="189"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="225"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="259"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="302"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="331"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC93417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="388" mass="42811" checksum="3A0A31CEC159ADB0" modified="2018-07-18" version="1">MKPPLSKLGHRRELIRQFTPNWFTMTMGTGIVALALGRTSELLPILWNLGATLWVINIALFLLFVSMYCARWIFFFDGAKRIFHHSVMCMFFGAIPMGLATIINGFLVFGIPLIGERAISIAFSLWWLDAAMALICGLLIPFFMFTRHDHSLQSMTAVWLLPIVAAEVTAASGGLLISHMNAGSSATQILFISYSLWGFSVLPALAVLVILFLRMVLHKLPGRDMAASSWLSIGPIGTGALGLLLLGTQAQRILISPDLISVGIVAHGFGILGATILLGYGFWWLVIAILTTLRYLRDGLPFNMGWWAFTFPIGVYSLATLSLADSTGIQWLYYFGYAFVSMLIFFWYVVMGSTLRGAYHGNVFFSPCISDGTGLQLPSKSEKQKVNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0C1</accession>
    <name>A0A2S9H0C1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">2-keto-3-deoxy-galactonokinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1790</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93403">
        <property type="protein sequence ID" value="PRC93403"/>
        <property type="gene ID" value="S2091_1790"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008671">
        <property type="term" value="F:2-dehydro-3-deoxygalactonokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034194">
        <property type="term" value="P:D-galactonate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.310">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007729">
        <property type="entry name" value="DGOK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042257">
        <property type="entry name" value="DGOK_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042258">
        <property type="entry name" value="DGOK_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05035">
        <property type="entry name" value="DGOK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="321" mass="34495" checksum="510541CC761FC834" modified="2018-07-18" version="1">MVTSQPSLIGIDWGSTSLRAYLFDADGAVLETRATTQGASGMADADSYLNTLYQLTGDWMQTGGRKNNLSVLACGMVGSAHGWQEVPYVECVADINKVAANLVKIHHQPVHIIPGLICSPDNLPPDVMRGEETQLIGALRNLPNLTSEACIVLPGTHSKWARTSHGTICAFATHMTGELFFVLRQHSVLGRLLPESGITRDDAAFLNGVRASRDQGYLGLSHQLFSVRSLGLTKNMNGMELTEYLSGLLIGHEVQAGLNWRKLAGLESAPLVLAGDPELCRRYVHAMSSYDVTDAVVLSDTAPAGLWSVALASGITRQSLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0E4</accession>
    <name>A0A2S9H0E4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1839</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93452">
        <property type="protein sequence ID" value="PRC93452"/>
        <property type="gene ID" value="S2091_1839"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="97" mass="10911" checksum="FC02DDA7CADCBDDC" modified="2018-07-18" version="1">MANQELQFTISLAQGNLILEALAERPFKQVFEIIGHLTQQAAILFPAEAGEESIGSFIVSVPQLRLILEVLGEIPYNRVNRLLHQLHQQLHEALDLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0L6</accession>
    <name>A0A2S9H0L6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1877</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93490">
        <property type="protein sequence ID" value="PRC93490"/>
        <property type="gene ID" value="S2091_1877"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001845">
        <property type="entry name" value="HTH_ArsR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00778">
        <property type="entry name" value="HTHARSR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00418">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50987">
        <property type="entry name" value="HTH_ARSR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH arsR-type" evidence="1">
        <location>
            <begin position="1"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="109" mass="12740" checksum="DF1D2F02E79B543E" modified="2018-07-18" version="1">MDIDKVFKALADPGRRRLLDLLHQESGQTLTALCEHMDMTRQAVTQHLHQLEEANLVAIIWQGREKLHYLNAVPLHEIYARWIEKFEHSRLGALQDLKMKLEGEDNEKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0U6</accession>
    <name>A0A2S9H0U6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1571</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93570">
        <property type="protein sequence ID" value="PRC93570"/>
        <property type="gene ID" value="S2091_1571"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007462">
        <property type="entry name" value="COV1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31876">
        <property type="entry name" value="PTHR31876"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04367">
        <property type="entry name" value="DUF502"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="205" mass="22637" checksum="C2A12ABE4DC73AEF" modified="2018-07-18" version="1">MLRKYFITGLLILVPLSITLWVIHSVIGLMDQSLLLLPMEWRPETLLGMHIPGVGTILTLLIILVTGLLTRNFIGNYVVAGWEALLNRIPIVNSIYSSVKQVSDTLFSSDGNAFRTAVLVQYPREGMWTIAFVTGTPSYAVQQHLTGDYVSIYVPTTPNPTSGFFLMVPKADVIELDMSVDVALKHIVSMGVVAPEQHNISKQPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1N4</accession>
    <name>A0A2S9H1N4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1462</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93853">
        <property type="protein sequence ID" value="PRC93853"/>
        <property type="gene ID" value="S2091_1462"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="497" mass="53774" checksum="8059AE0D829E560D" modified="2018-07-18" version="1">MLPIVIQEITQAAPVSRSKASSLITAPTVSPSVLNTLNIPASISMRHFCEAKFSNICNTCRDSGQAAQTMANHLATLLIHAGEVTAGNNAKFEVVGNLTNHLLGNLTRDDLTKAQSAANQIKARFHSDIDSQGSTQLDRTLNMLDLPYHKATHESGRMGHAREMHSDVRHFFGNNPYQDLANTLAYCHDHVQIKDDHGMGVGNSLHWGLNEIATAAALATLASESGVDAAGQEALLKVAGAVIPAGTAFNFMPNVGGDGKPGLGTIIEGMLRGKTLPANLSESGREIIAMAYTLAICDTQRNNLAGLARPTDDVIFKNASAVHRLLSNCAEKEPESFGTTFFDNGKLSEAGLALCSKLTSTVEVFEEFPHHTFSTPNLENGKPNNPLSRTFDPGSMTTEERDNAILQLIRNNGSFGSANVARDIESFSGEFSHPVLDHIKQKTILENPKTAFTDAYIKFADELKFQCEAGKMRMDEVLDQIKAMGGSVQRRNQFRPM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1T2</accession>
    <name>A0A2S9H1T2_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Flagellar M-ring protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">S2091_1519</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">The M ring may be actively involved in energy transduction.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Bacterial flagellum basal body</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the FliF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93910">
        <property type="protein sequence ID" value="PRC93910"/>
        <property type="gene ID" value="S2091_1519"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009431">
        <property type="term" value="C:bacterial-type flagellum basal body, MS ring"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003774">
        <property type="term" value="F:cytoskeletal motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071973">
        <property type="term" value="P:bacterial-type flagellum-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013556">
        <property type="entry name" value="Flag_M-ring_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000067">
        <property type="entry name" value="FlgMring_FliF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006182">
        <property type="entry name" value="FliF_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043427">
        <property type="entry name" value="YscJ/FliF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30046">
        <property type="entry name" value="PTHR30046"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30046:SF0">
        <property type="entry name" value="PTHR30046:SF0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01514">
        <property type="entry name" value="YscJ_FliF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08345">
        <property type="entry name" value="YscJ_FliF_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004862">
        <property type="entry name" value="FliF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01009">
        <property type="entry name" value="FLGMRINGFLIF"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00206">
        <property type="entry name" value="fliF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0975">Bacterial flagellum</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="14" id="KW-0966">Cell projection</keyword>
    <keyword evidence="14" id="KW-0969">Cilium</keyword>
    <keyword evidence="14" id="KW-0282">Flagellum</keyword>
    <keyword evidence="7 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="14"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="432"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="domain" description="YscJ_FliF" evidence="12">
        <location>
            <begin position="39"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="domain" description="YscJ_FliF_C" evidence="13">
        <location>
            <begin position="247"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="290"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR004862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF08345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="PRC93910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="492" mass="52826" checksum="C2DE11D2D3BDFACC" modified="2018-07-18" version="1">MTIFKQIWERLDQAARIGLVLCLFVLAGAMIGLSFWFLKPDYQVLFSDLAPADAAAMTTELDHMKIPYHLDGGGNTILVLADEVYKTRLKLVGRDLPLHGTIGFELFNNADIGMTEFAQKVNYQRALQGELTRTILSYEEIQAARVHLALPEQTLFKKTTAQAKASVSLTLKPGKTLQPHEVQGIQRLVAASVPDIQEQDVTVIDQHGVALTRPASSDSENTESGASNLDSKEAIERYFTHKVSDVLDRTFGAGQSIASVDVVLNHDAVKTTTENVLGSDDATPTGVIVHEHQTGQGSPPDTQQGTIQAGGPTHPNPATSTNRDVDYQVGRRVEQVVTGPGTIDKINVAVVVRQPLDASQIDRISDIIAKAVGIDKARGDGIAVYTITQFGTGQNTLAPTSAEQPATAAPVTASIDSVPETHSSARTAPTTVTIVLVSLIVPIVLIALGILLRSGKPGQAQPTPLTHQEREELLARVRHWLDAKSGKHGDIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1V8</accession>
    <name>A0A2S9H1V8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Glycosyl transferases group 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1135</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC93962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93962">
        <property type="protein sequence ID" value="PRC93962"/>
        <property type="gene ID" value="S2091_1135"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="441" mass="49962" checksum="C534112709AAD0C3" modified="2018-07-18" version="1">MIIIIYSDTNAGSIEKNLGMSEYSYYFVLKEFRPILEQLGIVVTVTDPAREVDTIYRNAQAHGETCVFLSFSPPHKTEINLDCPTIPVFAWEFNTIPQEIWDNDPRNDWRTVFAKLGCAITHSNFTVATARAAMTPTYPIISAPAPVWDRFARLRERANSGAVEIDIAGTVIDTNDTDITVFGPKQRHVPKPNLVRSAALAREQPVKLHLDGVVYTSVFNPYDGRKNWFDMIGAFCWAFRDHEDAVLVLKLTHHDIQPAVVSLLEDLCKLKPYQCRVVLISGYLADTEYEKLVAMTSYVVNTSHGEGQCLPLMEFMSCGIPAITPDHTAMVDYINGDNAFVVSSSTEPSHWPHDPRQAYRTLRYRIDWGSLRDAYLDSYHVFKHDQARYKKMAESAVTGLQKHCSQAVIAQRLREFIFAHPRLTSADRATFENKQKNVLVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1W3</accession>
    <name>A0A2S9H1W3_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 4">Phosphoribulokinase</fullName>
            <ecNumber evidence="3 4">2.7.1.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_1147</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 4">
            <text>ATP + D-ribulose 5-phosphate = ADP + D-ribulose 1,5-bisphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19365"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57870"/>
            <dbReference type="ChEBI" id="CHEBI:58121"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.19"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the phosphoribulokinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.19" evidence="3 4"/>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC93974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93974">
        <property type="protein sequence ID" value="PRC93974"/>
        <property type="gene ID" value="S2091_1147"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008974">
        <property type="term" value="F:phosphoribulokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006082">
        <property type="entry name" value="PRK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006083">
        <property type="entry name" value="PRK/URK"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00485">
        <property type="entry name" value="PRK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00478">
        <property type="entry name" value="PHRIBLKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00567">
        <property type="entry name" value="PHOSPHORIBULOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="61"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="121"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="158"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="197"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="231"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="271"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="308"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="350"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="domain" description="PRK" evidence="6">
        <location>
            <begin position="392"/>
            <end position="565"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC93974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="683" mass="76182" checksum="4F93F4514B65958C" modified="2018-07-18" version="1">MRKVCLHPMFFLGLAIRLALIIGLTPLAVSDWYVPFLDASISSVTLDPWSGWMTGGGTPVAFPYGYAMWLFFLPITLITKLIGAPLQYGYELTLLAADFCLLTTLHHLLPGRPRLLLAVYWLSPIVILASYALGLNDLVPALFLTLSIFFIRRVELKFAGALCAAAISAKLSMVVALPFFIIFLYNNKALRQRIAQFLLGFLVCSLILGVPFLFSYAALQMLFGNPEMGKVYRLALSLGDNVSIYIVPLVYMIMLYLAWRIRRLNFDLFQAITGMAFLLIVLMTPASPGWFVWSIPFLVLYQAMSGRIAILLIGVFSALYVLSTLLVTPLQLTNNSGFDLGSALHMSAQLGSHAASLLHTSMVAIGVVLAIRIWREAISRNDFFRLSRKPFVIGIAGDSGAGKDTFADSITALFGGHSVVKLSGDDYHLWDRQKPMWQVMTHLNPMSNDLEGFCRDLVSLTDGKSIQSKHYDHTTGKMSKPVQITSNDFIIASGLHALYLPILRDCYNLKIYLDIDEGLRRHFKLKRDVDKRGHTVERVLSSFEKREPDSERFIRPQSTYGDLTLALHPIHPRMLESLDDKHPLRLKLIVKTRHGFNELSLNRVLVGVCGLHVDIIVCDDGSEVQMIIEGEASAADVAMAAEMLCPKVLEFLDIPPKWQAGMAGLMQLITLSHISQALTKRFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1X7</accession>
    <name>A0A2S9H1X7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Sel1 repeat</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1126</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC93953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93953">
        <property type="protein sequence ID" value="PRC93953"/>
        <property type="gene ID" value="S2091_1126"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="160" mass="17860" checksum="BEC82483393F4E03" modified="2018-07-18" version="1">MGNFKNFAIIIWRLFAIGLVFASLTRPVLANDFDDAERYYADKDYTKAAQLYKESALSGNVKAQAILGMLYQYGRGLDMDYSKAISWYQKAANQGEVSAQDKLGSMYENGQGVAQDYKQAAFLYRKAADLGFADAQFHLGILYAIGGGVEQSYKHLVVHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1X9</accession>
    <name>A0A2S9H1X9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fatty acid hydroxylase superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1133</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC93960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93960">
        <property type="protein sequence ID" value="PRC93960"/>
        <property type="gene ID" value="S2091_1133"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008610">
        <property type="term" value="P:lipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006694">
        <property type="entry name" value="Fatty_acid_hydroxylase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04116">
        <property type="entry name" value="FA_hydroxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="78"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="111"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="153"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="180"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="domain" description="Fatty acid hydroxylase" evidence="2">
        <location>
            <begin position="114"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="325" mass="37385" checksum="A7A1136AAFF2171A" modified="2018-07-18" version="1">MWIFHNVINFLGLGGLVDLVNVQQFSLTTFATLAGIEALISPIAPIILVLEVGLLFWLNRRATFRISRHYKIPLMMYAANAVIPVYLTLKFFILTFNFFSKFALFQVESRLIYFLYAFLIWEFSHFVFHYSCHKVRLLWILHSPHHAPAQINLSLIYTAFFLHGLYATLVRTAICAILGVPLQLLIFVLIIDGCWGTLIHISEEIWHKGKPSGILGHIFLWPSDHRVHHANNPQYIDKNYCNTLPVWDKLFKTLQREIPEIKPQYGLARDVDQDSFVDTYFGEILLLFKDLKNAGSVKNALLYLLMPPGWKPKTGNLVNPSEAIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H211</accession>
    <name>A0A2S9H211_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1156</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC93983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93983">
        <property type="protein sequence ID" value="PRC93983"/>
        <property type="gene ID" value="S2091_1156"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002514">
        <property type="entry name" value="Transposase_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010921">
        <property type="entry name" value="Trp_repressor/repl_initiator"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01527">
        <property type="entry name" value="HTH_Tnp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48295">
        <property type="entry name" value="SSF48295"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="155" mass="17475" checksum="7DEFDE9609D9C87A" modified="2018-07-18" version="1">MTQTDQTAAQRTLRKPHRQHSIEFKRAVAEQALQQGACITHIAREHDIRPNLVHSWRQRYREGLLNAQSDQKLLPVALIESIAPSQSDKAPVPEETSPCSGFILLNAGQISMRIKGRADPMALKLILTELLSCYRPACRDPHLAGCGHHRYARRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H261</accession>
    <name>A0A2S9H261_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1245</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94072">
        <property type="protein sequence ID" value="PRC94072"/>
        <property type="gene ID" value="S2091_1245"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="125" mass="14396" checksum="9DB44B3789A5773B" modified="2018-07-18" version="1">MNNTFSLIKNYFKTAFRWQRGRQMSGYDKMLLLQSMWPLPFDCYILKFPEGAEIAPHVDAVKQGAHYRLNIVIKRAGSGGEFGCANPIYTSNRIKYFRPDVSEHSVTRVDKGSRYVLSIGWVRGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2B7</accession>
    <name>A0A2S9H2B7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Alpha/beta hydrolase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1266</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94093">
        <property type="protein sequence ID" value="PRC94093"/>
        <property type="gene ID" value="S2091_1266"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="71" mass="7801" checksum="024B4F2C20E5779D" modified="2018-07-18" version="1">MANMSHFKRLPSIQIPTKVIAGELDVSCPPELMRNDIAQQIPNARMHVIAGATHMISLTKPVELAALLLEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2M2</accession>
    <name>A0A2S9H2M2_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_0853</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94232">
        <property type="protein sequence ID" value="PRC94232"/>
        <property type="gene ID" value="S2091_0853"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007890">
        <property type="entry name" value="CHASE2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017181">
        <property type="entry name" value="Sig_transdc_His_kin_CHASE2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05226">
        <property type="entry name" value="CHASE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037347">
        <property type="entry name" value="STHK_CHASE2_PAS_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM01080">
        <property type="entry name" value="CHASE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="313"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="358"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="5">
        <location>
            <begin position="576"/>
            <end position="798"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC94232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="802" mass="88940" checksum="0A534B85425CB8DC" modified="2018-07-18" version="1">MKSTKQIQHIVRYEWLMLALALTVLAACLGFQHGLGRLDLLMYDKAIQLNQQAARNDIIIVAIDDYSIAQLGKWPWPRARHAQLLEKINQAQPTSIGLDVIFSEPESGSDSNGDAEFAHAMSDNNRTVLPITLENNGAGLVITQPFPTLATAARALAHINLEVDPDGFTRSIFLREGRENAWVPHFSLALYNIIKKRAIDDYSDLPSTSNKQLNTSSPNSWLRNSQFYIPFYGNQGHFKSVPYVSVLRGEVPAQFFAGKNVLIGATAVGMSDAYPTPVSGVDGAMPGIEINANILASLLDGRSIIMASPELCAAYSVIPVLIALFAYLLLSPRLALSCTILLFPLTLVSSFLALKSGIWLPPSAALIVLIIAYPLWSWRRLEAAIRYLNIEISRLNQEPSLLPEPLQKTTPNKQTSLFTDALAQRISSMEIAAKRVRDLRQFVTDSLQSLPDATIVTSVEGHVILSNQPADAYFNSLGNKNLADALLPYLFSTMLSPRPLEQAATHTFSWWHLLDLSKRELMKNGIEVSDTLKRDLIIKSAPCTNANKEHIGWIVGIIDISTIRQAERARDETLRFISHDMRAPQASILALLELQQEPKSALPQPEFLERVAKAAQVTLGLADNFVQLARAETEYYRLEVVNTQDIVMDACDEMWSLAKTKQIQINTVVSDECANDEALININRSLMTRVLTNLLSNAIKYSPENTTVTISIDKKIEFLNNRVIIQIADQGYGITPTDQLKLFRRFQRFAGANQPKNEGVGLGLAFVKLVLERHQAHISLTSKPNHGTTFTLSIPAYSEIPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2P0</accession>
    <name>A0A2S9H2P0_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Probable septum site-determining protein MinC</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">minC</name>
        <name evidence="9" type="ORF">S2091_0848</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 6">Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Interacts with MinD and FtsZ.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the MinC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94227">
        <property type="protein sequence ID" value="PRC94227"/>
        <property type="gene ID" value="S2091_0848"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000902">
        <property type="term" value="P:cell morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000917">
        <property type="term" value="P:division septum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051302">
        <property type="term" value="P:regulation of cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901891">
        <property type="term" value="P:regulation of cell septum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00267">
        <property type="entry name" value="MinC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016098">
        <property type="entry name" value="CAP/MinC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013033">
        <property type="entry name" value="MinC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036145">
        <property type="entry name" value="MinC_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007874">
        <property type="entry name" value="MinC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005526">
        <property type="entry name" value="Septum_form_inhib_MinC_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34108">
        <property type="entry name" value="PTHR34108"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03775">
        <property type="entry name" value="MinC_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05209">
        <property type="entry name" value="MinC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63848">
        <property type="entry name" value="SSF63848"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01222">
        <property type="entry name" value="minC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2 6" id="KW-0132">Cell division</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0717">Septation</keyword>
    <feature type="domain" description="MinC_N" evidence="8">
        <location>
            <begin position="7"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="domain" description="MinC_C" evidence="7">
        <location>
            <begin position="137"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00025606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF05209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC94227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="245" mass="25739" checksum="7E3C432912F146A3" modified="2018-07-18" version="1">MLSKNQRKPIEIKISTVVAIAVILFDADLTILEAAIKELTANSSDYYSEECAVIDVANIDCTDLDWAALIKLLKTNGINPVAVRNAPASSETQISLLGLSIDLGSKTAPLAEVATAPIPAPTPIPTPITASSLPPMIIDTPVRGGQRIYARGTDLIITAVVNSGAEVIADGSIHIYAPLRGRALAGASGNTAARIFTLSLEAELVSIAGIYRTFENGYPSLTPNAPLQIKLNGDRIDVVSIQIAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2W3</accession>
    <name>A0A2S9H2W3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major Facilitator Superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_0918</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94297">
        <property type="protein sequence ID" value="PRC94297"/>
        <property type="gene ID" value="S2091_0918"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="25"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="61"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="92"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="121"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="151"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="180"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="218"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="241"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="26"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC94297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="295" mass="31071" checksum="A634A540881DAA27" modified="2018-07-18" version="1">MLKQEVAEPSTANIAGVSQTPSVRLALVGLSFSMVLSSLGTSIVNVGLPTLAQAFSASFQQVQWVVIAYLLAITTLVVGIGRLGDLTGRRRLLLAGIALFTGASVVCGIASALWLLIAARAIQGLGAAAMMSLSLSFVGDLMPKEKTGSAMGLLGTMSAIGTALGPSLGGILIARIGWQAIFLINLPLGILTFLLVLRYLPVDRHNHKTIRGGFDKTGMLLTLTLAAYALAMTVGRGDFGLLNLTLLVAAAIGVVGFMRIEARVSTPLLQLKMFRNLALAFEHFCDFTVFKFIHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H317</accession>
    <name>A0A2S9H317_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0989</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94368">
        <property type="protein sequence ID" value="PRC94368"/>
        <property type="gene ID" value="S2091_0989"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="34" mass="3751" checksum="3DF7A9F21A33CF02" modified="2018-07-18" version="1">MMKKKLIYLMFTIVALMGFTASATAQNAPNMLSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H366</accession>
    <name>A0A2S9H366_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Very short patch repair endonuclease</fullName>
            <ecNumber evidence="5">3.1.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_1018</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">May nick specific sequences that contain T:G mispairs resulting from m5C-deamination.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the vsr family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="5"/>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94397">
        <property type="protein sequence ID" value="PRC94397"/>
        <property type="gene ID" value="S2091_1018"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00221">
        <property type="entry name" value="Vsr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004603">
        <property type="entry name" value="DNA_mismatch_endonuc_vsr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03852">
        <property type="entry name" value="Vsr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018267">
        <property type="entry name" value="VSR_endonuc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00632">
        <property type="entry name" value="vsr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0227">DNA damage</keyword>
    <keyword evidence="4 5" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5 6" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 5" id="KW-0540">Nuclease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR018267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC94397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="149" mass="17022" checksum="5869E22104DD2D7F" modified="2018-07-18" version="1">MSDVHSAAIRSKNMRAIKNKDTKPEIIIRQALHARGLRFRLHVKTLPGTPDIVLPKFKTVVFVNGCFWHGHRCHLSKTPKTRTEFWLSKISANMSRDVLIYKKLSDAGWRIAVIWECGIKGCGNQKLNALISEFVEWLNDPKSLGFELP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3I4</accession>
    <name>A0A2S9H3I4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0547</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94544">
        <property type="protein sequence ID" value="PRC94544"/>
        <property type="gene ID" value="S2091_0547"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="27"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="98" mass="11311" checksum="FD9765AD18CDD6C4" modified="2018-07-18" version="1">MLRKALLIIALLMTSIGFFCVLSGRSGALPILIWGVILLASVLFERWRYQPIDSGHDDWQETDEQFIDPETGKLTRVLYQTKTGERRYVQVDDSSKHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3L8</accession>
    <name>A0A2S9H3L8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative glutamine amidotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0571</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94568">
        <property type="protein sequence ID" value="PRC94568"/>
        <property type="gene ID" value="S2091_0571"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016811">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011697">
        <property type="entry name" value="Peptidase_C26"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044668">
        <property type="entry name" value="PuuD-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43235">
        <property type="entry name" value="PTHR43235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07722">
        <property type="entry name" value="Peptidase_C26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="250" mass="27130" checksum="AB936C3C82B4BE18" modified="2018-07-18" version="1">MAQPIVLIPACTKHIGAHPYHVAQMKYIDAVVRGSACVPLILPALGEELDWETVLQCADGVMLTGSPSNVHPDFFGQSVLDPSLPLDPARDATTLPLIRMAIQRGIPLLAVCRGTQEVNVALGGTLHQAVHEVEGFMDHREDKTASLDIQYAPAHNIKIMPNGRIAHILHGVSEMMVNSVHGQGIDQLAPGLQIEALAEDGLIEAYSVANAPGFTLAMQWHPEWKITENPLSMKLFDAFGAACREFKLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3N1</accession>
    <name>A0A2S9H3N1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0546</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94543">
        <property type="protein sequence ID" value="PRC94543"/>
        <property type="gene ID" value="S2091_0546"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="67" mass="7789" checksum="8E0C3C6FAC99767E" modified="2018-07-18" version="1">MRNNRNFCNRSENEQIWMMKNTWCDKCNAADFGLKDPIEYEENGKIIVEGKCSICSSIVLNEVLVEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3Q6</accession>
    <name>A0A2S9H3Q6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">MetW: methionine biosynthesis protein MetW</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0603</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94600">
        <property type="protein sequence ID" value="PRC94600"/>
        <property type="gene ID" value="S2091_0603"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010743">
        <property type="entry name" value="Methionine_synth_MetW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07021">
        <property type="entry name" value="MetW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02081">
        <property type="entry name" value="metW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="203" mass="22735" checksum="0C6B552EE8802EE3" modified="2018-07-18" version="1">MNFTELNQLRPDLAFIAHWIAPNSQVLDVGCGDGVMLDYLQTDKACQGYGIEIADDKVLECAKRGVQVIQQDMENGLGLFDDEAFATVLCLSSLQMMKNVEGLLTDIARVGREAIVSFPNFAYWPHRVALLRGRMPVSKSLPYEWYDTPNLRCATIADFAELANSVGLEVLECVALHDGRPVEWLANWRGSLAVFRLRRLKNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3R2</accession>
    <name>A0A2S9H3R2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NADH dehydrogenase FAD-containing subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0610</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NADH dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94607">
        <property type="protein sequence ID" value="PRC94607"/>
        <property type="gene ID" value="S2091_0610"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003954">
        <property type="term" value="F:NADH dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006116">
        <property type="term" value="P:NADH oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045024">
        <property type="entry name" value="NDH-2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43706">
        <property type="entry name" value="PTHR43706"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyr_redox_2" evidence="2">
        <location>
            <begin position="12"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="443" mass="48511" checksum="2133847B5492C87A" modified="2018-07-18" version="1">MINQDANVALQHIVIVGGGAGGLELAVRLGKKLGKTKKAIITLVDASPTHLWKPLLHQVAAGTMDSHADKRGYFALAHSHHFDFRFGRMDGLDRANKQLFLAPVLDEDGEEILPRSVLSYDSLVIALGSQTNDFGTPGAREHCIMLDTPVTAERFHHRLLSQCLRAQAQIRERGEGRFTVTIIGGGATGVELAAELHMTTKILSSYGLVNFHPEKELKIVIVDAAKRLLAMLPERVSTAAERELRSLDVQIYANEQVVEVSKEGVRMASGTFIPSGIVVWAAGIKAPDFLKELDGLETNRINQLVVTPTLQTSRDPAIFSIGDCSACAQGEGMPNVPPRAQSAHQQAELLARSLIRSVQGKSLLPFVYKDYGSLVSLGNYSTVGNLMGSLSSGSLFIEGTVAKIMYWSLHKHHQIVVNGWFHTWLTTWADLINRVKNPRIKLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H454</accession>
    <name>A0A2S9H454_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 11">Delta-aminolevulinic acid dehydratase</fullName>
            <ecNumber evidence="4 11">4.2.1.24</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">S2091_0768</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>2 5-aminolevulinate = H(+) + 2 H2O + porphobilinogen</text>
            <dbReference type="Rhea" id="RHEA:24064"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58126"/>
            <dbReference type="ChEBI" id="CHEBI:356416"/>
            <dbReference type="EC" id="4.2.1.24"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; coproporphyrinogen-III from 5-aminolevulinate: step 1/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Homooctamer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the ALAD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.24" evidence="4 11"/>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94765">
        <property type="protein sequence ID" value="PRC94765"/>
        <property type="gene ID" value="S2091_0768"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00251">
        <property type="reaction ID" value="UER00318"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004655">
        <property type="term" value="F:porphobilinogen synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006782">
        <property type="term" value="P:protoporphyrinogen IX biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001731">
        <property type="entry name" value="ALAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030656">
        <property type="entry name" value="ALAD_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11458">
        <property type="entry name" value="PTHR11458"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00490">
        <property type="entry name" value="ALAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001415">
        <property type="entry name" value="Porphbilin_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00144">
        <property type="entry name" value="DALDHYDRTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01004">
        <property type="entry name" value="ALAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00169">
        <property type="entry name" value="D_ALA_DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0350">Heme biosynthesis</keyword>
    <keyword evidence="7 11" id="KW-0456">Lyase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 11" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Schiff-base intermediate with substrate" evidence="9">
        <location>
            <position position="205"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with substrate" evidence="9">
        <location>
            <position position="260"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="245"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00020771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR001415-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR001415-5"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU004161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PRC94765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="338" mass="37036" checksum="4D366A4777D59B49" modified="2018-07-18" version="1">MPHSHKPSNFPAIRLRRMRKDAFSRALMRENTITSSDLIYPVFIVEGVNQREAVASMPGVERISVDILLTVAEDCVALGIPVIALFPVINPSLKTPDGIEATNPDGLIPRAVHELKSRFPELGVLTDIALDPYTSHGQDGLIDADGYVLNDETCAMLVRQALTHAKAGVDIVAPSDMMDGRIGAIRTALESHHYIHTRIMAYSAKYASAFYGPFRDAVGSAGNLGKSSKATYQMDPANSDEALREVALDLAEGADMVMVKPGMPYLDVVRRVKDEFKVPTFAYQVSGEYAMIKAAAQNGWLDHDKTMMEAMMSFKRAGADGVLTYFARDIARLLNIKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H467</accession>
    <name>A0A2S9H467_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0777</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94774">
        <property type="protein sequence ID" value="PRC94774"/>
        <property type="gene ID" value="S2091_0777"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="77" mass="8145" checksum="34BFAC1B10312977" modified="2018-07-18" version="1">MKFFSRLSWIALVAGIMFCISACGQKGRLVVPVKPPAVSTPYPVATPKENTENGADSEIKPEAAASTPEVSTPPNKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4H8</accession>
    <name>A0A2S9H4H8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0036</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94841">
        <property type="protein sequence ID" value="PRC94841"/>
        <property type="gene ID" value="S2091_0036"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="100" mass="10969" checksum="B819FF1B122BE125" modified="2018-07-18" version="1">MAYMISIKFNPPGRILQQIGERAKAMRLVQNLSRESVCTRSGVPLSTLKRFETTGQIGTAQLIAIAIALDAVEDIGNLFVAKPIKSIDQLAQSKRQRGTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4Q0</accession>
    <name>A0A2S9H4Q0_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">ATP:glutamine synthetase adenylyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">ATase</fullName>
        </alternativeName>
        <domain>
            <recommendedName>
                <fullName evidence="5">Glutamine synthetase adenylyl-L-tyrosine phosphorylase</fullName>
                <ecNumber evidence="5">2.7.7.89</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="5">Adenylyl removase</fullName>
                <shortName evidence="5">AR</shortName>
                <shortName evidence="5">AT-N</shortName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="5">Glutamine synthetase adenylyl transferase</fullName>
                <ecNumber evidence="5">2.7.7.42</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="5">Adenylyl transferase</fullName>
                <shortName evidence="5">AT</shortName>
                <shortName evidence="5">AT-C</shortName>
            </alternativeName>
        </domain>
    </protein>
    <gene>
        <name evidence="5" type="primary">glnE</name>
        <name evidence="8" type="ORF">S2091_0051</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>[glutamine synthetase]-L-tyrosine + ATP = [glutamine synthetase]-O(4)-(5'-adenylyl)-L-tyrosine + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:18589"/>
            <dbReference type="Rhea" id="RHEA-COMP:10660"/>
            <dbReference type="Rhea" id="RHEA-COMP:10661"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:46858"/>
            <dbReference type="ChEBI" id="CHEBI:83624"/>
            <dbReference type="EC" id="2.7.7.42"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>[glutamine synthetase]-O(4)-(5'-adenylyl)-L-tyrosine + phosphate = [glutamine synthetase]-L-tyrosine + ADP</text>
            <dbReference type="Rhea" id="RHEA:43716"/>
            <dbReference type="Rhea" id="RHEA-COMP:10660"/>
            <dbReference type="Rhea" id="RHEA-COMP:10661"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:46858"/>
            <dbReference type="ChEBI" id="CHEBI:83624"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.7.89"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the GlnE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.89" evidence="5"/>
    <dbReference type="EC" id="2.7.7.42" evidence="5"/>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94856">
        <property type="protein sequence ID" value="PRC94856"/>
        <property type="gene ID" value="S2091_0051"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008882">
        <property type="term" value="F:[glutamate-ammonia-ligase] adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047388">
        <property type="term" value="F:[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008152">
        <property type="term" value="P:metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000820">
        <property type="term" value="P:regulation of glutamine family amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00802">
        <property type="entry name" value="GlnE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023057">
        <property type="entry name" value="GlnE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005190">
        <property type="entry name" value="GlnE_rpt_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013546">
        <property type="entry name" value="PII_UdlTrfase/GS_AdlTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30621">
        <property type="entry name" value="PTHR30621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08335">
        <property type="entry name" value="GlnD_UR_UTase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03710">
        <property type="entry name" value="GlnE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1 5 8" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GlnE" evidence="6">
        <location>
            <begin position="73"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="domain" description="GlnD_UR_UTase" evidence="7">
        <location>
            <begin position="294"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="domain" description="GlnE" evidence="6">
        <location>
            <begin position="557"/>
            <end position="790"/>
        </location>
    </feature>
    <feature type="domain" description="GlnD_UR_UTase" evidence="7">
        <location>
            <begin position="815"/>
            <end position="910"/>
        </location>
    </feature>
    <feature type="region of interest" description="Adenylyl removase" evidence="5">
        <location>
            <begin position="1"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="region of interest" description="Adenylyl transferase" evidence="5">
        <location>
            <begin position="460"/>
            <end position="930"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC94856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="930" mass="104608" checksum="7F97090CC323AB22" modified="2018-07-18" version="1">MNSTSRYAQLNRLNTSRFFSRWAQAGANADANSNTAHNSPTRTEQINELAELSLTPATFAHFLQKETNLPRQANNPNGLSLPHALRRLRNLVVCTLIEKDLTGKADLNEVVTVMSSFADFAVQTALAALTLEMQAQYGIPVAEDSGEIQELIVLGMGKLGGAELNISSDIDLIFTYAEDGETKAAAGQKNLSNHEFFSRLGKKLIAALSEIGEDGFTFRVDMALRPNGASGPLVASFGMLEEYLLVQGREWERYAWVKARAITGFPSQIAALKKIVQPFVYRRYLDFAVIDALRAMHSQIRAEVIRHETRHPDRANNVKLGRGGIREIEFLTQVFQLIRGGREPLLRNRSTRETLAILANLSIIDPKIVAQLLASYTFLRNLEHRLQYLDDAQTHSMPANPADGEIIAQMMGYTDLAELSVELAKHRAFVAHQFDIIFGATESKAGSKDPEAPNFSMSLADSDNQEVLLHLLSKLAFQNPADGAEIITRSLQAPRLRSISEASKNKCMMLLNRAVVMIAALPDQHAETLQRLLNLLEAIVRRTAYLSLLIEYPHSLERLIRMMHSSDWAARYLIRHPILLDELLDIATLHQAPDWVAFAAELNQQLNLHADDTERQLETLREMHHSQLFRLLAQDLEGMLTVEHLADQLSQLADIMVAATIKAVWRTVTQRHRETPLFSVVAYGKLGGKELGYASDLDVVFIYDDQDQEAPAQYAKLVQRFITWMTSHTPAGVLFDIDIALRPDGASGLMVSSIQAFERYQTQSAWAWEHQALTRARCCTGPVELVEKFDALRQQILCQAREPETLKQEVLTMRNKMREANPVQPDKFDLKHSPGGMIDIEFMVQYLVLRYAHNYPQLCANYGNIALLITCGELGLIQPEHARPVADIYRHWRKQQHMIRLQGIDQAKIDSEIAAEEAQQVVALWEYLFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4Z1</accession>
    <name>A0A2S9H4Z1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Type IV pilus modification protein PilV</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0244</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95049">
        <property type="protein sequence ID" value="PRC95049"/>
        <property type="gene ID" value="S2091_0244"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013362">
        <property type="entry name" value="Pilus_4_PilV"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02523">
        <property type="entry name" value="type_IV_pilV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC95049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="195" mass="20562" checksum="8B0E25BD29B78235" modified="2018-07-18" version="1">MNPATFHRHLNTLSAPSDTGFTIIEILISVLVLTIGILGAIKLQLSSMQTTQQSNFNSVAVKLASEMADKMRGNHVQMQQSDNAFLKVDFNSSDGAPATASMCYGKTECSPDQLAAADISEWLNQLNNALPGARALICRDSSPWSSGANSLTWNCAAGSGNNVSIVIKLGWAEKNGASTSAATNLPPRLAIAVNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5M4</accession>
    <name>A0A2S9H5M4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0436</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95241">
        <property type="protein sequence ID" value="PRC95241"/>
        <property type="gene ID" value="S2091_0436"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015432072" evidence="1">
        <location>
            <begin position="22"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC95241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="243" mass="27123" checksum="274F00D0DCAF42E7" modified="2018-07-18" version="1">MKIVIASSALIAVMFSTPVLADPDDSILTNYSENGLRQIDFKLGSLGQTGQPSQDASTLGFGYGFTENWFSEIYVGYVKIGSGATEFDSAAWQNTFLLTNSQSPVDVGLYTEIEYEHDRTAGEQLTFGPLLQTELGLTKINFNLLFQRNYFADFSNPMQMGYQWQVKQHLNLPVDLGIQGFGEFGQWDHWAAQKDQSHRLGPALFGKIALSEKNVINYNAAILFDVFDQTHATTFRMQAVLGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5W8</accession>
    <name>A0A2S9H5W8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Outer membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_0471</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95276">
        <property type="protein sequence ID" value="PRC95276"/>
        <property type="gene ID" value="S2091_0471"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000184">
        <property type="entry name" value="Bac_surfAg_D15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039910">
        <property type="entry name" value="D15-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12815">
        <property type="entry name" value="PTHR12815"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01103">
        <property type="entry name" value="Omp85"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1134">Transmembrane beta strand</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015444924" evidence="4">
        <location>
            <begin position="22"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="domain" description="Omp85" evidence="5">
        <location>
            <begin position="297"/>
            <end position="600"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC95276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="600" mass="66166" checksum="51583F14864F7298" modified="2018-07-18" version="1">MRLIFCAALMLNLWVSLPCLAQEINPDPESAVSEDASTSTEPEQALSTQFDLVENSAIDSKIHDLLKNHVSVLNRPADKITSSELRLLRFSVRREIANILATEGYFSPLINFDVQIKKSEKILVHIKVELGPVTKVTTAQVNFVGDAVPPELQQSIQSNWGLQKGATFRDDDWSHAKTKALESLTEHSYAAAKITDSQATIQDQQADLSVLLDSGPVFRIGELRIQGLNLYKPWLLDRYHPPVTGDVYSRESLLKFQRTLQNSPYFSSVSVSVDPDPEVAAAVPVEVLVKERQEHDVGLGAGYSTNTGARGEVSYRDRDFVGDAYDLRSVLRIEQLRQIGYADIYLPPRLSGYLDSFGVLFDRSDISGLLTATSSFGAKRVITEDSVERRLGLSFVYEQSTVSGDEETHAKALVSSIGWTWRAVNNVFEPRQGQITQLDISGATKHLISDQNFLRLYGKYQRWIPVATRDVIILRIEAGYVLAADSVGIPEDYLFRAGGTASVRGYSYQSLGVNQADGVVGGRVLTTATAEYVHWLEANWGVAGFVDVGDAADHVSDLSLKQGIGMGLRYKTPAGPIALDLAYGRQTEKLRLDFSIGIAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GS64</accession>
    <name>A0A2S9GS64_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">RHS repeat-associated core domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4731</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000056">
        <property type="protein sequence ID" value="PRC90564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90564">
        <property type="protein sequence ID" value="PRC90564"/>
        <property type="gene ID" value="S2091_4731"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001826">
        <property type="entry name" value="RHS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022385">
        <property type="entry name" value="Rhs_assc_core"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00394">
        <property type="entry name" value="RHSPROTEIN"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03696">
        <property type="entry name" value="Rhs_assc_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC90564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="174" mass="19260" checksum="CC9AA11171DDE4AD" modified="2018-07-18" version="1">MYGKSASGSSLDAETNLHYNYYRDYDPSTGRYVESDPIGLGGGISTYGYVSANPFSYVDPTGLVEVPGYIPNSKIVSFVREKAAELNLELSKCSDKDILDFVKYIPKSVADDINKSWDKRPTKGIFGGSPTPEQSRINREEYLKERAMIDHAMTDFLQSKKSRGEPCGCKLGGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSC1</accession>
    <name>A0A2S9GSC1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4695</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000046">
        <property type="protein sequence ID" value="PRC90588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90588">
        <property type="protein sequence ID" value="PRC90588"/>
        <property type="gene ID" value="S2091_4695"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="42" mass="4242" checksum="F69BAE5C4FD92272" modified="2018-07-18" version="1">MRRGGHSVQAAHSAPEGLGLDGGRRNTLSHAVQGGSIPCTVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSE3</accession>
    <name>A0A2S9GSE3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4684</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000044">
        <property type="protein sequence ID" value="PRC90616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90616">
        <property type="protein sequence ID" value="PRC90616"/>
        <property type="gene ID" value="S2091_4684"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC90616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="197" mass="22487" checksum="AD10999BAC4C1136" modified="2018-07-18" version="1">MGEFVVVLKWVEINNGESMHLDLMRDEAKKFPKVNNHNDIHSIRIWHCKYKTLQVLEEFPNVEELVVASFPDDSLDFLVTLSKLKYLSIIHLPKISSLDPLAKLLHLDSLSLSTSPAWDAQGKCTIIQSLAPLTEIEPLHHLELFGVCPENKLLSDLDKCKNLVTARFSQFQKGEGERFYKTTGVVNEFNPKPTFKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GT61</accession>
    <name>A0A2S9GT61_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Sel1 repeat</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4371</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000033">
        <property type="protein sequence ID" value="PRC90878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90878">
        <property type="protein sequence ID" value="PRC90878"/>
        <property type="gene ID" value="S2091_4371"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC90878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="434" mass="47984" checksum="D23336D60F70F8AC" modified="2018-07-18" version="1">MGNFKNFAIIIWRLFAIGLVFALLTRSVLANDLDDAERYYADKDYTKAAQLYKESALSGNVKAQVILGMLYQYGRGLDMDYSKAISWYQKAANQGEVSAQDKLGSMYENGQGVAQDYKQAAFLYRKAADLGFADAQFHLGILYAIGGGVEQSYQQALAWYTKAAGVVIPLPPGAYNHKISLTPEAAAYNIGVLYEYGLGVKKDLGKAGDWYARAAWRNLPSAQFKLGFLQEFGGDSIGQSYRNAEHWYQKATEQGYALAQSQLTMMRFGVQTPCEQNDTDYSVARASAELPLKPGLWKIQSYIVDKHITESSIVNKSCYAEKTVCVTRPSSLPQGKFWPQLIDGKVGLQPGSVSETDTELASTLNVQSSVPIYSLRVSRTRSRSSDDQYDYKSYANFGAPWLLVTPITAVGESKIDRIATFVGACPKPEQDILK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GT82</accession>
    <name>A0A2S9GT82_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Aldose 1-epimerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4330</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000032">
        <property type="protein sequence ID" value="PRC90929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90929">
        <property type="protein sequence ID" value="PRC90929"/>
        <property type="gene ID" value="S2091_4330"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008183">
        <property type="entry name" value="Aldose_1/G6P_1-epimerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014718">
        <property type="entry name" value="GH-type_carb-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01263">
        <property type="entry name" value="Aldose_epim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="SSF74650"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC90929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="296" mass="32856" checksum="EE4FA4B5A1CA2BAC" modified="2018-07-18" version="1">MQILHLHCGTLSVGLAPTLGGALTYFRTQGSNGNVDWMRPWSDHGRGPLDSASFVMVPFFSWLEKDDFMFGDRHVMLPPSGFGFNRSLLGQGWTTAWTVDELTQTLHRQRATLSHHNHGGAWPWRYHAQQTIELNPERLSITVTLRNKDTSPMPAGIGLHTFFPWSKGLRVQTQVKAMHLMSELGLPYAADPNHPAVQMLAEGLELQTGLDNVFEQWNGRCTISGQHGSLRMTADSPYRFLCINAPHNADYCCVEPVTHTTNAIHVQNIDGAETGFVLLEPGASMTATAHFQPTSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTK4</accession>
    <name>A0A2S9GTK4_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Type II secretion system protein H</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">General secretion pathway protein H</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">S2091_4314</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000031">
        <property type="protein sequence ID" value="PRC91018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91018">
        <property type="protein sequence ID" value="PRC91018"/>
        <property type="gene ID" value="S2091_4314"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015627">
        <property type="term" value="C:type II protein secretion system complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015628">
        <property type="term" value="P:protein secretion by the type II secretion system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022346">
        <property type="entry name" value="T2SS_GspH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12019">
        <property type="entry name" value="GspH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0488">Methylation</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="21"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="domain" description="GspH" evidence="12">
        <location>
            <begin position="64"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004377"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF12019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PRC91018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="225" mass="24086" checksum="696832D51F7CD779" modified="2018-07-18" version="1">MFLIQYRSFKHWSFTKLLRPASRAGGFTLVELLITMTIAAILLAVAVPQFKSAFQSQQASTEITNLLNDMAYARSEAIREGQYVTICALPAPPLTTGVSCGTSNNWQNGWIIYSDSGTSSTTTNSATQTYAASTSTLLRVQNAFTSTDTLTNSTGSANSSVHTVSFNRDGFVPGLTAGAGLLFTLDNSPVNNSATRCLWLDVSGRQYIQIHNQTAATGQGTNTCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTR9</accession>
    <name>A0A2S9GTR9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Gram-negative porin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_4128</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000028">
        <property type="protein sequence ID" value="PRC91127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91127">
        <property type="protein sequence ID" value="PRC91127"/>
        <property type="gene ID" value="S2091_4128"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046930">
        <property type="term" value="C:pore complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015288">
        <property type="term" value="F:porin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006811">
        <property type="term" value="P:ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00342">
        <property type="entry name" value="gram_neg_porins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033900">
        <property type="entry name" value="Gram_neg_porin_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023614">
        <property type="entry name" value="Porin_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13609">
        <property type="entry name" value="Porin_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0406">Ion transport</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0626">Porin</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1134">Transmembrane beta strand</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015702329" evidence="4">
        <location>
            <begin position="21"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="domain" description="Porin_4" evidence="5">
        <location>
            <begin position="11"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF13609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC91127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="382" mass="40018" checksum="F77BE6882A95031F" modified="2018-07-18" version="1">MNYKHFAIGLVSLASGVAHAQSSTTIYGVIDAGTRYSSGLGLSATSSPSASNASTTGLASGVDRSGRFGFTGTEDLGGGYQALFKLESDLYTNTGSTNANTGTGKDAAAATTDKFFEREASVGIATPFGKVLFGRQQSVIRDIIDEIDAIDGRFTGFNPNLQFTSLNSASLVTSSGTYYGTGDPGNGSMMRQDNAVKYIAQSGPVTGTLLYSFGGVAGSTPSGSSAQAGLSYRDGGLVLSAAYENLNNNNDTLKLTAYTAGGRYTFGDWQIAANYGSNSADNTPTTQIKTDIYSIGTTYAATSAIDLTLGYYNVNRTWTNDVKPDATINRVIGFAEYKFSKSTLVYLELDHNKWGGDVTQFQGGAANKSTTTGFTIGINHQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTT3</accession>
    <name>A0A2S9GTT3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Arylsulfatase A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_4143</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="PTM">
        <text evidence="3">The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the sulfatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000028">
        <property type="protein sequence ID" value="PRC91142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91142">
        <property type="protein sequence ID" value="PRC91142"/>
        <property type="gene ID" value="S2091_4143"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008484">
        <property type="term" value="F:sulfuric ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024607">
        <property type="entry name" value="Sulfatase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00523">
        <property type="entry name" value="SULFATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015739744" evidence="5">
        <location>
            <begin position="31"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="575"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="domain" description="Sulfatase" evidence="6">
        <location>
            <begin position="37"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="modified residue" description="3-oxoalanine (Cys)" evidence="3">
        <location>
            <position position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR600917-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC91142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="606" mass="67759" checksum="EE55CD90507791A8" modified="2018-07-18" version="1">MEQRVKNKISVVCRITLLIFSVGMFSFSHATGTKAQPNIVILVADDWGFSDVGAFGSEIATPNIDNLAKQGLKFSNFHVAASCSPTRAMLLTGVDNHRNGMGNMPETMPFEHQGKPGYKGTLNDDAVTLATMLKDNGYHTYITGKWHLGKEPGELPPQRGFERSFIQADSGSDNWENRPYIFLYDKAYWFEQGKPATLPEDYYSSKFIVDKAIDYIATDKKNGKPFFAYLGFQANHIPVQAPRSFIDKYQGVYKDGWTALRTARRNRAAEMGLIPKDTEMVTMASTANWDTLSPEQKKYDARRMEVYAAMAEAMDYHVGRFVEHLKQTGEFDNTVFVFLSDNGAEPTDPYKILSVKLWLYMNYTNDFDRLGDKGAYDAIGPSWASAAASPLSTYKFFAGEGGLRTPLIISGVPNMKKDQISSTFAHVTDIVPTLLDIAGIKPHDDHYQGKTVEPMVGNSMLPLLQGKSMRVHSADQAIGYELSGNAALFKGDYKLLKNLGPVGDSQWHLYNIANDPGEVHDLQQGMPQLFQSMKNDYDNYARANHVLPMPAGYNYITQGQLYAVHHVLIPKLKASLPKILFGLFVLISGLFLIRRRKRNTTIPKKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTU6</accession>
    <name>A0A2S9GTU6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Response regulator receiver domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_4132</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000028">
        <property type="protein sequence ID" value="PRC91131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91131">
        <property type="protein sequence ID" value="PRC91131"/>
        <property type="gene ID" value="S2091_4132"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="5"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="123" mass="13399" checksum="97A81285DDDBAE99" modified="2018-07-18" version="1">MMSKTIMVVDDSISLREVVGLALKDAGYDVIEGCDGNDALSKLSGQKIHLIISDVNMPNMDGISFIKAIKLLPHYRFTPIIMLTSESQEVKKREGQAAGAKAWVVKPFKLDVLLGAVQMLAIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GU06</accession>
    <name>A0A2S9GU06_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4112</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000027">
        <property type="protein sequence ID" value="PRC91217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91217">
        <property type="protein sequence ID" value="PRC91217"/>
        <property type="gene ID" value="S2091_4112"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="45" mass="5222" checksum="C553D4967A39A59B" modified="2018-07-18" version="1">MLAKPLNTLKFLKNSGGYIKPPENKPKKHDLFKIHCHEQHWSPAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GU20</accession>
    <name>A0A2S9GU20_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative MetA-pathway of phenol degradation</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4020</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000026">
        <property type="protein sequence ID" value="PRC91235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91235">
        <property type="protein sequence ID" value="PRC91235"/>
        <property type="gene ID" value="S2091_4020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025737">
        <property type="entry name" value="Phenol_MetA_deg_put"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13557">
        <property type="entry name" value="Phenol_MetA_deg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015677641" evidence="1">
        <location>
            <begin position="25"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="260" mass="27966" checksum="9D4E59EF1602BFFD" modified="2018-07-18" version="1">MKISNYTILLLSLVVLLTPAFANAACPNPDDPIATDRSSVANSSSVLPAASIQFENGISNTRDQGITTYDLTETRVRIGLGGCTEFLVDLPNYTHAEVSNGGVSGFSNLGPAVKHQFPEFISGLILSATLGVYLNTGDSTIAGAGPAPYAQLPWSVDLGSNWSINGMLSATSHRHDVNNNAAYQTSVYLDRIINDNADMFVEYINDYQLAAMTVNRVDIGGSYRLTPHQQLDAKVGAGLNSAAPSWYFTVGYSFRFDHLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GU21</accession>
    <name>A0A2S9GU21_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Flavohemoprotein</fullName>
            <ecNumber evidence="6">1.14.12.17</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="18">Flavohemoglobin</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="17">Hemoglobin-like protein</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="19">Nitric oxide dioxygenase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="24" type="ORF">S2091_4099</name>
    </gene>
    <organism evidence="24 25">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="24 25" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="24 25">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="16">Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>NADH + 2 nitric oxide + 2 O2 = H(+) + NAD(+) + 2 nitrate</text>
            <dbReference type="Rhea" id="RHEA:19469"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16480"/>
            <dbReference type="ChEBI" id="CHEBI:17632"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.14.12.17"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>NADPH + 2 nitric oxide + 2 O2 = H(+) + NADP(+) + 2 nitrate</text>
            <dbReference type="Rhea" id="RHEA:19465"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16480"/>
            <dbReference type="ChEBI" id="CHEBI:17632"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.14.12.17"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the globin family. Two-domain flavohemoproteins subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="24">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.12.17" evidence="6"/>
    <dbReference type="EMBL" id="PUGF01000027">
        <property type="protein sequence ID" value="PRC91204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91204">
        <property type="protein sequence ID" value="PRC91204"/>
        <property type="gene ID" value="S2091_4099"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008941">
        <property type="term" value="F:nitric oxide dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019825">
        <property type="term" value="F:oxygen binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005344">
        <property type="term" value="F:oxygen carrier activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051409">
        <property type="term" value="P:response to nitrosative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009636">
        <property type="term" value="P:response to toxic substance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.490.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008333">
        <property type="entry name" value="Cbr1-like_FAD-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001709">
        <property type="entry name" value="Flavoprot_Pyr_Nucl_cyt_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000971">
        <property type="entry name" value="Globin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009050">
        <property type="entry name" value="Globin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012292">
        <property type="entry name" value="Globin/Proto"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023950">
        <property type="entry name" value="Hmp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43396:SF3">
        <property type="entry name" value="PTHR43396:SF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00970">
        <property type="entry name" value="FAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00042">
        <property type="entry name" value="Globin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00371">
        <property type="entry name" value="FPNCR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46458">
        <property type="entry name" value="SSF46458"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="SSF52343"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="SSF63380"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01033">
        <property type="entry name" value="GLOBIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0216">Detoxification</keyword>
    <keyword evidence="12" id="KW-0274">FAD</keyword>
    <keyword evidence="10" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="9 21" id="KW-0349">Heme</keyword>
    <keyword evidence="14" id="KW-0408">Iron</keyword>
    <keyword evidence="11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-0520">NAD</keyword>
    <keyword evidence="13" id="KW-0521">NADP</keyword>
    <keyword evidence="21" id="KW-0561">Oxygen transport</keyword>
    <keyword evidence="25" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="21" id="KW-0813">Transport</keyword>
    <feature type="domain" description="GLOBIN" evidence="22">
        <location>
            <begin position="5"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="23">
        <location>
            <begin position="149"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00008414"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00014637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00025094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00030024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00030929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00033187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="RuleBase" id="RU000356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="PROSITE" id="PS01033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="EMBL" id="PRC91204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="410" mass="44764" checksum="8A3B26A07B4BE6EC" modified="2018-07-18" version="1">MLSIETRAVLDASVPVLREHGVAITTSFYASMFAAHPELKNIFNMGNQKSGAQQQSLASALFAYAANYDNQAALLPVVSRIVQKHVSVGIRADHYPIVGKYLLGGIAHVLGAAATPALLAAWGDAYGDLAGLFISEEQAQYRSKSIEPGQCRQVTVNKKVIESEQVTSFYLVATDGNPLPAFLPGQYISVAMQVADGGKQLRQLRQYSLSDAADKPYWRISVKREVAQAELDAGMVSGLIHDQIQVGDTLWVGMPCGDFVLHHESELASNRAPLILISAGVGITPVMSMLHSSLAKQQRQVRFFHATRSGKYHALRSELHALAQHNKQLDIHICYEHPETSDVIGRDYISAGKLDLNAVNADLLPTNGHYYLCGPSPFMQQQRRALIARGIPEAQIRHEVFGPELIGHLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GU96</accession>
    <name>A0A2S9GU96_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Inorganic pyrophosphatase</fullName>
            <ecNumber evidence="5">3.6.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Pyrophosphate phospho-hydrolase</fullName>
            <shortName evidence="5">PPase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ppa</name>
        <name evidence="6" type="ORF">S2091_4056</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>diphosphate + H2O = H(+) + 2 phosphate</text>
            <dbReference type="Rhea" id="RHEA:24576"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="EC" id="3.6.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homohexamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the PPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.1" evidence="5"/>
    <dbReference type="EMBL" id="PUGF01000026">
        <property type="protein sequence ID" value="PRC91271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91271">
        <property type="protein sequence ID" value="PRC91271"/>
        <property type="gene ID" value="S2091_4056"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004427">
        <property type="term" value="F:inorganic diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006796">
        <property type="term" value="P:phosphate-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00412">
        <property type="entry name" value="pyrophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.80.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00209">
        <property type="entry name" value="Inorganic_PPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008162">
        <property type="entry name" value="Pyrophosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036649">
        <property type="entry name" value="Pyrophosphatase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10286">
        <property type="entry name" value="PTHR10286"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00719">
        <property type="entry name" value="Pyrophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50324">
        <property type="entry name" value="SSF50324"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="5">
        <location>
            <position position="30"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="44"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="56"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="66"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="71"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="103"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="142"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC91271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="179" mass="19995" checksum="C8BAE7766EEAEFDD" modified="2018-07-18" version="1">MSLNKVSAGRDLPHDFNVIIEIPMNADPIKYEVDKETGAIFVDRFMGTAMHYPCNYGYVPQTIAGDGDPVDVLVITPFALIPGVVVRCRAIGVLNMSDEGGQDAKVLAVPIDKILPIYSHWQKPEDMNELRLRQIQHFFEHYKDLEKGKWVKVEGWSGPDEAHAEILNGVANYTASLTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUE1</accession>
    <name>A0A2S9GUE1_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">5'-nucleotidase SurE</fullName>
            <ecNumber evidence="5">3.1.3.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Nucleoside 5'-monophosphate phosphohydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">surE</name>
        <name evidence="7" type="ORF">S2091_4061</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>a ribonucleoside 5'-phosphate + H2O = a ribonucleoside + phosphate</text>
            <dbReference type="Rhea" id="RHEA:12484"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:18254"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58043"/>
            <dbReference type="EC" id="3.1.3.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
        <text evidence="5">Binds 1 divalent metal cation per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the SurE nucleotidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.5" evidence="5"/>
    <dbReference type="EMBL" id="PUGF01000026">
        <property type="protein sequence ID" value="PRC91276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91276">
        <property type="protein sequence ID" value="PRC91276"/>
        <property type="gene ID" value="S2091_4061"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106411">
        <property type="term" value="F:XMP 5'-nucleosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1210.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00060">
        <property type="entry name" value="SurE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030048">
        <property type="entry name" value="SurE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002828">
        <property type="entry name" value="SurE-like_Pase/nucleotidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036523">
        <property type="entry name" value="SurE-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30457">
        <property type="entry name" value="PTHR30457"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01975">
        <property type="entry name" value="SurE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64167">
        <property type="entry name" value="SSF64167"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00087">
        <property type="entry name" value="surE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SurE" evidence="6">
        <location>
            <begin position="3"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="8"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="9"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="39"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="91"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC91276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="245" mass="26376" checksum="360EB10407F1C658" modified="2018-07-18" version="1">MKILISNDDGYLAPGLLALADAMSKIAEVVVVAPERNRSGASNALTLDKPLSVSKAGDNVYFVDGTPSDCVHIALTGLLDYRPDLIVSGINQGQNMGDDTLYSGTVAAATEGFLFGIPAIAFSQAEKGWGFIDDAARFALNLVKHKLDDLHKPYLLNVNIPNCHYADIKGVQVTRLGRRHQSEPVIKSADPRGNPIYWIGPPGAAKDASEGTDFHAVAQGYVSVTPLQVDLTHTQQLLELKKVWQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUI1</accession>
    <name>A0A2S9GUI1_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">50S ribosomal protein L21</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rplU</name>
        <name evidence="6" type="ORF">S2091_3937</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4 5">This protein binds to 23S rRNA in the presence of protein L20.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the 50S ribosomal subunit. Contacts protein L20.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4 5">Belongs to the bacterial ribosomal protein bL21 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000024">
        <property type="protein sequence ID" value="PRC91392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91392">
        <property type="protein sequence ID" value="PRC91392"/>
        <property type="gene ID" value="S2091_3937"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01363">
        <property type="entry name" value="Ribosomal_L21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036164">
        <property type="entry name" value="L21-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028909">
        <property type="entry name" value="L21p-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001787">
        <property type="entry name" value="Ribosomal_L21"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018258">
        <property type="entry name" value="Ribosomal_L21_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21349">
        <property type="entry name" value="PTHR21349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00829">
        <property type="entry name" value="Ribosomal_L21p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141091">
        <property type="entry name" value="SSF141091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00061">
        <property type="entry name" value="L21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01169">
        <property type="entry name" value="RIBOSOMAL_L21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4 5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 5" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC91392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="103" mass="11198" checksum="7D46D7E6C84AAFEE" modified="2018-07-18" version="1">MYAVIKTGGKQYKVAAGQKLKIEQIPADIGSEITIDQVLAVGAGDTLKVGAPLVAGATVVATVVAHGRHDKVTIFKMRRRKHYQKHQGHRQNYTELHIVSING</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUX2</accession>
    <name>A0A2S9GUX2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3776</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000022">
        <property type="protein sequence ID" value="PRC91498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91498">
        <property type="protein sequence ID" value="PRC91498"/>
        <property type="gene ID" value="S2091_3776"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="516" mass="56467" checksum="7366705FBB8FA6FF" modified="2018-07-18" version="1">MTYNLAQLAQLSTEQALLGGGDARLTLDPQTGVNKYGCGSHPDSTLLAFGSSTGSTISERGFAAAHALQQRFSQRDNEQENSSSEVTLYRHELERIRLQFNQLCDFSIHTDIASIFAASGTDLHLICAQLMAAHNEQPLHIIMMDACETGSGVAPAVRGQHFSNHAALGGTVTAFDTLTDAHPVEVTSIGLRDTNGKKRPLSDIDAEVEDLIQQAISQQQRVLLIMIDISKTGLIAPSPSYITTLRQRYSDQVDVLIDACQFRIANPTLNAYLKLGCMVTLTGSKFLTGPVFSGVLLIPPNLITRLSTQKLPASLADYSAQAEWPENWLATEQLSNTVNWGLLLRLEAALAELSAFRAIPETEVNAFLLEFAGAMQQALQSSPHFSLMAESRLDRHPIYSRHCWDQIPTIFPFLLQHQAGQPITREQTLQIYKQLQFPIQASEAETLSPAIANLRCQLGQPVLCGTQHGIAVSALRMCASSRLIIDACAHGAESRQQVIQQALNALEKAEYLIKIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUZ1</accession>
    <name>A0A2S9GUZ1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">S2091_3661</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ElaB/YgaM/YqjD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000021">
        <property type="protein sequence ID" value="PRC91545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91545">
        <property type="protein sequence ID" value="PRC91545"/>
        <property type="gene ID" value="S2091_3661"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043605">
        <property type="entry name" value="DUF883_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043604">
        <property type="entry name" value="DUF883_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010279">
        <property type="entry name" value="YqjD/ElaB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35893">
        <property type="entry name" value="PTHR35893"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05957">
        <property type="entry name" value="DUF883"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19029">
        <property type="entry name" value="DUF883_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="81"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="domain" description="DUF883" evidence="11">
        <location>
            <begin position="8"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="domain" description="DUF883_C" evidence="12">
        <location>
            <begin position="72"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="40"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004377"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF05957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF19029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PRC91545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="101" mass="11033" checksum="9A7FCC7C2B00806C" modified="2018-07-18" version="1">MSSHTNNDDLMHDLQAVIKDAEVLMKSSALPNGEDFRSAKERIETTLKNAKDEIIRLEKLVVGKTKEAAQATDTYVKDNPWQAVGLGAAVGLVIGLLISRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GV80</accession>
    <name>A0A2S9GV80_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Peptidase family M23</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_3682</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000021">
        <property type="protein sequence ID" value="PRC91566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91566">
        <property type="protein sequence ID" value="PRC91566"/>
        <property type="gene ID" value="S2091_3682"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045834">
        <property type="entry name" value="Csd3_N2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011055">
        <property type="entry name" value="Dup_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016047">
        <property type="entry name" value="Peptidase_M23"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19425">
        <property type="entry name" value="Csd3_N2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01551">
        <property type="entry name" value="Peptidase_M23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51261">
        <property type="entry name" value="SSF51261"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="32"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="domain" description="Csd3_N2" evidence="7">
        <location>
            <begin position="192"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M23" evidence="6">
        <location>
            <begin position="322"/>
            <end position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF19425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC91566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="463" mass="50386" checksum="E4A4569015F48166" modified="2018-07-18" version="1">MPSLNKTTNSAVTSALDSVTKLVSGSTRKTRIITVSALFLTLVAFGAAGVAPLAPDASDLPVRQIVEQLQIPTLEAQMQALEESDQQFIHEEKVQRGDTLASLLQRLGVDDAAANTFIKSDNTARLVMQQKAGKTVRAQTNEDGELQWLQTNISDNRDNLSQVKNITITRQDGTDTFKVAEASTALERHIEMHTGEITSSLFAATDAAQIPDAVASQLVDMFSTNIDFKSDLRRGDHFQLVYETFWQNGEMVSTGKVLAGEFNNAGRSYQSVWFDDAPGTGGYYGFDGKSMKKAFLKSPIAFTRISSGFSMRVHPISGQWKQHTGVDFAAPTGTPIRASADGVVDVAGPSGGYGNLVVLKHWGSYSTAYGHMSRFAAGMRKGVKVQQGDIIGYVGSTGWATGPHLHYEFRVNNKAQDPLKIKVEQAQTLTAVNQPRFNTTVQDVQHRFALLRPNDAPAKIATR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVA3</accession>
    <name>A0A2S9GVA3_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Outer membrane protein assembly factor BamD</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">bamD</name>
        <name evidence="4" type="ORF">S2091_3581</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Part of the Bam complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the BamD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000020">
        <property type="protein sequence ID" value="PRC91643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91643">
        <property type="protein sequence ID" value="PRC91643"/>
        <property type="gene ID" value="S2091_3581"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043165">
        <property type="term" value="P:Gram-negative-bacterium-type cell outer membrane assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051205">
        <property type="term" value="P:protein insertion into membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd15830">
        <property type="entry name" value="BamD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00922">
        <property type="entry name" value="OM_assembly_BamD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017689">
        <property type="entry name" value="BamD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039565">
        <property type="entry name" value="BamD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13525">
        <property type="entry name" value="YfiO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03302">
        <property type="entry name" value="OM_YfiO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="4" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0802">TPR repeat</keyword>
    <feature type="domain" description="YfiO" evidence="3">
        <location>
            <begin position="45"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="82"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC91643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="274" mass="31766" checksum="C69FE9A860EAAFE7" modified="2018-07-18" version="1">MQNLMQKNSLKRLRSVTVLIFITVFGLSACGLLPEKSDETKTWSAARLYQEAKSDLANGSYESAIKNLEKLESRFPFGTYAQQAQMEIPYVYYKQGDQAQALASIERFIKLHPNHENLDYIYYLRGLVNFNDQVSFFQALAKQDMTERDPKAAREAFDAFKALVTRFPGSKYTPDALLRMKYLVNTMAQYDLHVAKYYFRRGAYLASANRAQSAIKEYPDAPAIEEALYVLYNSYDKMGLIELRDDANRVFTTNFPNSKFTHASKEEKSWWQFW</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVB5</accession>
    <name>A0A2S9GVB5_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 6">Thiazole synthase</fullName>
            <ecNumber evidence="4 6">2.8.1.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">thiG</name>
        <name evidence="8" type="ORF">S2091_3722</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 6">Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>1-deoxy-D-xylulose 5-phosphate + 2-iminoacetate + [sulfur-carrier protein ThiS]-C-terminal Gly-NH-CH2-C(O)SH = 2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate + [sulfur-carrier protein ThiS]-C-terminal Gly-Gly + 2 H(+) + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:26297"/>
            <dbReference type="Rhea" id="RHEA-COMP:12908"/>
            <dbReference type="Rhea" id="RHEA-COMP:12909"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57792"/>
            <dbReference type="ChEBI" id="CHEBI:62899"/>
            <dbReference type="ChEBI" id="CHEBI:77846"/>
            <dbReference type="ChEBI" id="CHEBI:90619"/>
            <dbReference type="ChEBI" id="CHEBI:90778"/>
            <dbReference type="EC" id="2.8.1.10"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 6">Cofactor biosynthesis; thiamine diphosphate biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homotetramer. Forms heterodimers with either ThiH or ThiS.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the ThiG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.10" evidence="4 6"/>
    <dbReference type="EMBL" id="PUGF01000021">
        <property type="protein sequence ID" value="PRC91606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91606">
        <property type="protein sequence ID" value="PRC91606"/>
        <property type="gene ID" value="S2091_3722"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00060"/>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990107">
        <property type="term" value="F:thiazole synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009229">
        <property type="term" value="P:thiamine diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd04728">
        <property type="entry name" value="ThiG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00443">
        <property type="entry name" value="ThiG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033983">
        <property type="entry name" value="Thiazole_synthase_ThiG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008867">
        <property type="entry name" value="ThiG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34266">
        <property type="entry name" value="PTHR34266"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05690">
        <property type="entry name" value="ThiG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0704">Schiff base</keyword>
    <keyword evidence="5 6" id="KW-0784">Thiamine biosynthesis</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ThiG" evidence="7">
        <location>
            <begin position="9"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="DXP binding" evidence="6">
        <location>
            <begin position="191"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="DXP binding" evidence="6">
        <location>
            <begin position="213"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with DXP" evidence="6">
        <location>
            <position position="104"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="165"/>
        </location>
        <ligand>
            <name>1-deoxy-D-xylulose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:57792"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF05690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC91606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="262" mass="27714" checksum="9D4DF7B09C04EC41" modified="2018-07-18" version="1">MSKENTGFTIAGKTYSSRLLVGSGKYRDLEQTRLATEASGADIITVAIRRVNIGQDPNAPSLLDVVPPSRYTILPNSAGCYNAKDAIYTLQLGRELLGGHKLCKLEVLGDEKSLFPNMPETLIAAEILVKDGFDVMVYCSDDPIQAKMLEDIGCVAVMPLASLIGSGMGILNPWNLSLIIERATVPVLVDAGVGTASDAAIAMELGCDGVLMNTAIAGAQDPIRMARAMRLAVEAGREAFLAGRIPKRFSASASSPMSGRVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVJ3</accession>
    <name>A0A2S9GVJ3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3497</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000019">
        <property type="protein sequence ID" value="PRC91742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91742">
        <property type="protein sequence ID" value="PRC91742"/>
        <property type="gene ID" value="S2091_3497"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="41" mass="4648" checksum="DF7593F3B60EF150" modified="2018-07-18" version="1">MIPKPSPLSLLWYEVAIICSWLSLQGTYKIKRRLCANALIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVZ9</accession>
    <name>A0A2S9GVZ9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="11">D-alanyl-D-alanine carboxypeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">S2091_3450</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the peptidase S11 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000018">
        <property type="protein sequence ID" value="PRC91894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91894">
        <property type="protein sequence ID" value="PRC91894"/>
        <property type="gene ID" value="S2091_3450"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009002">
        <property type="term" value="F:serine-type D-Ala-D-Ala carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018044">
        <property type="entry name" value="Peptidase_S11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001967">
        <property type="entry name" value="Peptidase_S11_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00768">
        <property type="entry name" value="Peptidase_S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00725">
        <property type="entry name" value="DADACBPTASE1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="3" id="KW-0133">Cell shape</keyword>
    <keyword evidence="5" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="11" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015473152" evidence="9">
        <location>
            <begin position="21"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S11" evidence="10">
        <location>
            <begin position="24"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-ester intermediate" evidence="6">
        <location>
            <position position="52"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="55"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="109"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="214"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR618044-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR618044-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC91894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="277" mass="29875" checksum="BA3756C270BBC417" modified="2018-07-18" version="1">MKLIKLSAACLLLITTSAFALPFGSQSALVIDENSGQVLLEKNADNVVPIASLTKLMTAMVVIDAKQDMEAPISIDEQDVDVIKHSTSRVPVGATLPRKDVLQLALMSSDNRAAASLARTYPGGIVAFEAAVHAKLLALGMTHTTIEEPTGLSFHNTSTASDLVKMASAASQYTDITRITTDSRDMISIKGRQVEYHNTNGFVGKKGWDIMLSKTGYTTEAGRCIIMKIKAAGKNVIMVLLNAGANSTRNRDAMNVRRFVSDEKVAVVKTRHNKQRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GW57</accession>
    <name>A0A2S9GW57_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">F1/F0 ATPase, Methanosarcina type, subunit 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3270</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000017">
        <property type="protein sequence ID" value="PRC91928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91928">
        <property type="protein sequence ID" value="PRC91928"/>
        <property type="gene ID" value="S2091_3270"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017581">
        <property type="entry name" value="AtpR-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12966">
        <property type="entry name" value="AtpR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03165">
        <property type="entry name" value="F1F0_chp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="65"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="103" mass="11370" checksum="4F21B525726298C4" modified="2018-07-18" version="1">MNDFINLAGAFAVGIVIGALFFGGLWWTTLKGVVSDNPALWFFGSLLLRTVGMLVGLHLVAGDDWHRAIVCLLGFIVARFAVLRFFHVRQLRLPPSLDASEEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWF9</accession>
    <name>A0A2S9GWF9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000016">
        <property type="protein sequence ID" value="PRC92065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92065">
        <property type="protein sequence ID" value="PRC92065"/>
        <property type="gene ID" value="S2091_3200"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007139">
        <property type="entry name" value="DUF349"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03993">
        <property type="entry name" value="DUF349"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="878" mass="98129" checksum="AC996085574A1103" modified="2018-07-18" version="1">MLALIVFNFDAMFDFFFKKRSTAKSSETTQLLTQQQEQADAVAAKFADKQSVKQSELAAAASFAGQESAALAFILQSGYADARYQAAMHLHSAEALMQVSQAMRNTDRRVSKLAQEKLAALQNQQKMTSAVQACLAQGQQLLENTQLMVNQVALWDKERLALGEHGLSLLPIKVTLDERLQAQLELQRQTLQTSSSLRALVETALPLEQLQAQLAECLQQWQAIEVSPLLASLPKNQFNQLNDDVALAQSHVQQLTQLTQLIAARHEALQVWQTAEQLALENVQKEWKKLALTGAALSDEQQEVVHQQEQQLKLIFARIAPTASASVHKTHTKKIAIEAGENQAVPAIDIKSVLVALEQALEEGSLQQALDLDKTLRQEVLPARGELAQRLQVLRAELNRLLDWAKWGGNVSREELIKVADGLVAEDVALTAPEIAKQVGGLRARWKELDRTSGTAAKSVWERFDEACGRAYQIADAHFKQQAQLRLDNLTLAQAQLAAIDVVIADLQNQLPDWKTQLAYIQKVKLEWRKTGSIDRKLKARLESEFEQKIQTLSQPLMVAREAAIGVRQQLIQSVIDIAATDREAADKVQLAQQRWQQEALNLPLERKDEQDLWRQFRAACDAVFAQRKANADEQKQRRNLGVVAKQACCEAVEQSLEASLSSAEIMAVLRKAKQEWRDLSVQHRQAGLDARFETALNALETRHSELLLKDKQAELVHLYAKIKLCQQVEAANNAATKLVEPEITEQSAAWQAEWKLLTTSKAPAELNKLLTQRFNTALAVIKNQQVADAAQVAANLAQFEERLLRVEILRGLPSPAELTQQRLQLQVRDLQSAMKNRDATDAYLSNLYVLCALPVSLKAPHEQRFQLVLTDYSGISR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWH2</accession>
    <name>A0A2S9GWH2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fatty acid desaturase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3348</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000017">
        <property type="protein sequence ID" value="PRC92006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92006">
        <property type="protein sequence ID" value="PRC92006"/>
        <property type="gene ID" value="S2091_3348"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005804">
        <property type="entry name" value="FA_desaturase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012171">
        <property type="entry name" value="Fatty_acid_desaturase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19353">
        <property type="entry name" value="PTHR19353"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00487">
        <property type="entry name" value="FA_desaturase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="41"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="215"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="domain" description="FA_desaturase" evidence="2">
        <location>
            <begin position="66"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="335" mass="37484" checksum="645995E6C78D7AD0" modified="2018-07-18" version="1">MSQINPAPVKPTSAMRNSVKLKLRDIFSAEEISQLTARSDLMGWSAVLFTWGVIALVFVALAVWPHPLMWCIAFIILGGRQLSLAIMMHDASHGTLFKTKWLNDVLADYVCGSPVGVDIKQYRQHHLTHHIKTGTDADTDKSLSAPFPTSRSSLLRKFARDLSGISGIKREFGLLLMNAGVIRWTVASDIAKLPQEGRTWRDYAQSIARNSWKNVAFHLLLITLLTVAGYPWLYLAWLGAYLTTYSLFMRIRSIAEHACTEASTDMFLNTRSTRAGLLARATVAPLRVNHHIEHHLMASVPYFKLPAMHQMLRERGYLAAPPGYMDVLKLASTPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWI8</accession>
    <name>A0A2S9GWI8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3224</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000016">
        <property type="protein sequence ID" value="PRC92089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92089">
        <property type="protein sequence ID" value="PRC92089"/>
        <property type="gene ID" value="S2091_3224"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="70" mass="7720" checksum="ADA8D7C4471CB748" modified="2018-07-18" version="1">MDTDTDTVFAHVRDERSDTEVEIAVNRGLAVALLEGPLEGLKIMQAAGVPNEICARVLNSTTRRRASDWH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWN2</accession>
    <name>A0A2S9GWN2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3259</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000016">
        <property type="protein sequence ID" value="PRC92124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92124">
        <property type="protein sequence ID" value="PRC92124"/>
        <property type="gene ID" value="S2091_3259"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="111"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="314" mass="36079" checksum="FD039D4131C76159" modified="2018-07-18" version="1">MAAKMKFSFNLLGAPITLDDAKFAPKQDYRCEKCTATVLYNAGSNPERFGRSVKVEHYFKLKKGFTHEDLCKFNILGQVKIIAKESDKNFIKQLKDGQYELRLLLPSEGNSSNQVNAARKENDHDNDTKNSATTSYVSSGNLNSYLNTAAAVLKLRAFCEEHSEVENHLTLRFDTISVHWKDFYFEIDHYKRLYRILSKATVIYPIAVSGKVKEIKKLESKTKLGTFFWKIDLDVPFEKPDENGTVKKTQVSISTSESRLIDQIKGNEDIVIFGKWRAEKVNSQPNQNKESKVKTWENLPLKFNLTHQRQIIKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWT6</accession>
    <name>A0A2S9GWT6_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 7">Citrate synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_3103</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>acetyl-CoA + H2O + oxaloacetate = citrate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16845"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:16947"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="EC" id="2.3.3.16"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Carbohydrate metabolism; tricarboxylic acid cycle; isocitrate from oxaloacetate: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 5 8">Belongs to the citrate synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92187">
        <property type="protein sequence ID" value="PRC92187"/>
        <property type="gene ID" value="S2091_3103"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00223">
        <property type="reaction ID" value="UER00717"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004108">
        <property type="term" value="F:citrate (Si)-synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd06114">
        <property type="entry name" value="EcCS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016142">
        <property type="entry name" value="Citrate_synth-like_lrg_a-sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016143">
        <property type="entry name" value="Citrate_synth-like_sm_a-sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002020">
        <property type="entry name" value="Citrate_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019810">
        <property type="entry name" value="Citrate_synthase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024176">
        <property type="entry name" value="Citrate_synthase_bac-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036969">
        <property type="entry name" value="Citrate_synthase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010953">
        <property type="entry name" value="Citrate_synthase_typ-I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00285">
        <property type="entry name" value="Citrate_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001369">
        <property type="entry name" value="Citrate_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00143">
        <property type="entry name" value="CITRTSNTHASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48256">
        <property type="entry name" value="SSF48256"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01798">
        <property type="entry name" value="cit_synth_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00480">
        <property type="entry name" value="CITRATE_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 7" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="active site" evidence="6">
        <location>
            <position position="310"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010566"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR001369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR001369-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC92187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="433" mass="48367" checksum="78C4C910FBC9887C" modified="2018-07-18" version="1">MTNSETKATLTFSDGSAPLEMPIYKGTVGPDVIDIRKLYAATGMFTYDPGFMSTAACNSAITYIDGDKGELLYRGYPIEQLAAKGDFLESCYLLLNGELPNTAQKEEFVYMVSRHTMVHEQMQFFFRGFRRDAHPMSVLVGTVGALASFYHDSLDINNPRHREVSAIRLIAKMPTLVAMAYKYSIGQPFVYPKNELSFSANFMHMMFSTPCEEYKINDVLVRALDRILILHADHEQNASTSTVRLAGSSGANPFACIAAGIACLWGPAHGGANEAALSMLEQIGSVDNIPEFIRQVKDKNSSVKLMGFGHRVYKNYDPRAKLMRETCYEVLAELGLENDPLFKLAMALEKIALEDEYFVSRKLYPNVDFYSGIVQRALGIPTALFTGIFAMARTIGWVAQWKEMISDPEQKIGRPRQLFVGETTRTVKPIAER</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWU2</accession>
    <name>A0A2S9GWU2_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">S2091_3087</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92171">
        <property type="protein sequence ID" value="PRC92171"/>
        <property type="gene ID" value="S2091_3087"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013767">
        <property type="entry name" value="PAS_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00989">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="38"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="9">
        <location>
            <begin position="90"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="10">
        <location>
            <begin position="172"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="9">
        <location>
            <begin position="232"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="10">
        <location>
            <begin position="303"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="7">
        <location>
            <begin position="380"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="8">
        <location>
            <begin position="628"/>
            <end position="745"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="346"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="4">
        <location>
            <position position="678"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC92171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="761" mass="84011" checksum="F58D48A539E0CF34" modified="2018-07-18" version="1">MFTMKNTPIDKLMEIGFGLTLAVLLLIGGIAYSLSSPIVGFFIGACVILLLVFLALMFTRIQREIQAQAASSINKIQPALLKAGSLQDAIFNSANFSSIATDAHGVIQIFNVGAERMLGYEAADVVDKITPAGISDAHELILRAEALSLEFDTRITPGFEALVFKASRGIEDIYELTYIRKDSSRFPAIVSVTALRDAEDKIIGYLLIGTDNTARKQVEAEQALLYQRLRDQQFYTRSLIESNIDALMTTDHRGIISDVNQQMEALTGCTRDELIGAPFKNYFTEPERAEAAITRVLREGKVTNYELTAHARDGKETVVSYNATTFYDRDRRLQGVFAAARDVTDRKQFEHRLQENNVELESAKAAAEKANLAKSDFLSSMSHELRTPLNAVLGFAQLMASEVPPPTAAQKMSIDQILQAGWYLLRLINEILDLALVESGKVTMSQESISLTDVLQDCQSMIEPQAHSRGIQMTFMHVDTPFYVHADRTRVKQVLINLLSNAIKYNRPGGGVIVQCELRAENWVRISVKDTGIGLSTDQLTQLFQPFNRLGQEVSTEEGTGIGLVVTKQLIELMGGTIGVESSVGIGSVFWVELQASVAPELMYGETSNLNIDQQTHNSKNPDSDRRTLLYVEDNPANLALVEQLIARRSDLKLLTAINGHLGIQLARTFQPDIILMDINLPGISGFGALRILREDPLTAHIPVLALSANAVPRDIEKGMEAGFFRYLTKPIKVDEFMEALNTAVSYTAENDVGDEVSKIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWZ2</accession>
    <name>A0A2S9GWZ2_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Periplasmic serine endoprotease DegP-like</fullName>
            <ecNumber evidence="7">3.4.21.107</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">S2091_3137</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>Acts on substrates that are at least partially unfolded. The cleavage site P1 residue is normally between a pair of hydrophobic residues, such as Val-|-Val.</text>
            <dbReference type="EC" id="3.4.21.107"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the peptidase S1C family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.107" evidence="7"/>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92221">
        <property type="protein sequence ID" value="PRC92221"/>
        <property type="gene ID" value="S2091_3137"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041489">
        <property type="entry name" value="PDZ_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011782">
        <property type="entry name" value="Pept_S1C_Do"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001940">
        <property type="entry name" value="Peptidase_S1C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13180">
        <property type="entry name" value="PDZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17820">
        <property type="entry name" value="PDZ_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00834">
        <property type="entry name" value="PROTEASES2C"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="SSF50156"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="SSF50494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02037">
        <property type="entry name" value="degP_htrA_DO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 7" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0720">Serine protease</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="7" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="PDZ" evidence="9">
        <location>
            <begin position="306"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="domain" description="PDZ" evidence="9">
        <location>
            <begin position="399"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="98"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="6">
        <location>
            <position position="146"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="6">
        <location>
            <position position="176"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="6">
        <location>
            <position position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR611782-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU364067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC92221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="504" mass="53735" checksum="84CE67C373BDE630" modified="2018-07-18" version="1">MIKISIQPPHNQRPTMNKFLSILLAATVTLVVPVAGLVTATPAFAALPSFDFTELVEKTSPAVVNIRTTEKISVNQDGNADEEMQELFKRFFGIPMPQQGPGGAAPTPRKRVPAKPAPGATEEEVPRGVGSGFIVSQDGYVLTNAHVVDGADEVYVKLTDKREFKAKVIGIDKRTDVAVVKIEGTKLPWLAIGDSDKIKAGEWVIAIGSPFDLDNSVSAGIVSAKSRDTGDFLNLIQTDVAVNPGNSGGPLINMRGEVVGINSQIYSRSGGFMGISFAVPIDEAMRVVDQLRSTGKVSRSRIGIKLSEVPKDVAESFGLSKGQGAFISMVEPGLPADKAGIVAGDIVLEFNGQPVTKWTELSRIVANTKPGTKSAVTLWSKGKTRTVTLVTGEMEQDKPTKTAKEKEAEVESNLLGLNVINLTDDQKRDLKVTAGVIVDNVDGSAARAGLQPGDLITQLNNNDIKDVKQFNALVAKLDPKKVAVVLVRRGDSSQFVPLRPTPAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GX33</accession>
    <name>A0A2S9GX33_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Aquaporin Z</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">aqpZ</name>
        <name evidence="11" type="ORF">S2091_2938</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 10">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Cell membrane</location>
            <topology evidence="10">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="10">Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the MIP/aquaporin (TC 1.A.8) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92279">
        <property type="protein sequence ID" value="PRC92279"/>
        <property type="gene ID" value="S2091_2938"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015250">
        <property type="term" value="F:water channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00333">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1080.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01146">
        <property type="entry name" value="Aquaporin_Z"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023271">
        <property type="entry name" value="Aquaporin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034294">
        <property type="entry name" value="Aquaporin_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023743">
        <property type="entry name" value="Aquaporin_Z"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000425">
        <property type="entry name" value="MIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022357">
        <property type="entry name" value="MIP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45724">
        <property type="entry name" value="PTHR45724"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00230">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00783">
        <property type="entry name" value="MINTRINSICP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81338">
        <property type="entry name" value="SSF81338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00861">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00221">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="5 10" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0677">Repeat</keyword>
    <keyword evidence="7 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="80"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="131"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="162"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="203"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="NPA 1" evidence="10">
        <location>
            <begin position="62"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="NPA 2" evidence="10">
        <location>
            <begin position="184"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="site" description="Involved in tetramerization or stability of the tetramer" evidence="10">
        <location>
            <position position="19"/>
        </location>
    </feature>
    <feature type="site" description="Selectivity filter" evidence="10">
        <location>
            <position position="42"/>
        </location>
    </feature>
    <feature type="site" description="Selectivity filter" evidence="10">
        <location>
            <position position="172"/>
        </location>
    </feature>
    <feature type="site" description="Selectivity filter" evidence="10">
        <location>
            <position position="181"/>
        </location>
    </feature>
    <feature type="site" description="Selectivity filter" evidence="10">
        <location>
            <position position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC92279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="230" mass="23852" checksum="2717308790B537B8" modified="2018-07-18" version="1">MKQYGAEFFGTFWLVLGGCGSAVLAAGFPGLGIGFVGVSLAFGLTVLTMAYAIGHISGCHLNPAVSIGLWVGGRFPAKQVIPYIIAQVLGGLVAGGVLYLIASGKAGFSVAGGFASNGFGEHSPGKYSMEAAFLCEVVMTMMFLLIIMGATDKRAPAGFAPLPIGLGLTLIHLISIPVTNTSVNPARSTAVALYVGDWAVSQLWMFWVAPIMGAILGAVIYRFIASEEKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GX45</accession>
    <name>A0A2S9GX45_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative translation initiation inhibitor yjgF family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2951</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92292">
        <property type="protein sequence ID" value="PRC92292"/>
        <property type="gene ID" value="S2091_2951"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06150">
        <property type="entry name" value="YjgF_YER057c_UK114_like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035959">
        <property type="entry name" value="RutC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006175">
        <property type="entry name" value="YjgF/YER057c/UK114"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035709">
        <property type="entry name" value="YoaB-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47328">
        <property type="entry name" value="PTHR47328"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01042">
        <property type="entry name" value="Ribonuc_L-PSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55298">
        <property type="entry name" value="SSF55298"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="122" mass="13260" checksum="3F411D790211D3B3" modified="2018-07-18" version="1">MQNQEIKRFHVGTRMSEMAVYNRTVYLAGQVTADDSLDIAGQTSSVLAQIDTLLAEAGTDKSHILMCQIYLSDLTHFAAMNQVWEGWVAKGNTPPRATVQAALANPAWLIEVVITAALKAAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GX79</accession>
    <name>A0A2S9GX79_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Amino-acid acetyltransferase</fullName>
            <ecNumber evidence="8">2.3.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">N-acetylglutamate synthase</fullName>
            <shortName evidence="8">AGS</shortName>
            <shortName evidence="8">NAGS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">argA</name>
        <name evidence="10" type="ORF">S2091_2986</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>acetyl-CoA + L-glutamate = CoA + H(+) + N-acetyl-L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:24292"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:44337"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="EC" id="2.3.1.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 1/4.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="8">In bacteria which possess the bifunctional enzyme ornithine acetyltransferase/N-acetylglutamate synthase (ArgJ), ArgA fulfills an anaplerotic role.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the acetyltransferase family. ArgA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.1" evidence="8"/>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92327">
        <property type="protein sequence ID" value="PRC92327"/>
        <property type="gene ID" value="S2091_2986"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00068">
        <property type="reaction ID" value="UER00106"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004042">
        <property type="term" value="F:acetyl-CoA:L-glutamate N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0103045">
        <property type="term" value="F:methione N-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006526">
        <property type="term" value="P:arginine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04237">
        <property type="entry name" value="AAK_NAGS-ABP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01105">
        <property type="entry name" value="N_acetyl_glu_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036393">
        <property type="entry name" value="AceGlu_kinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001048">
        <property type="entry name" value="Asp/Glu/Uridylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033719">
        <property type="entry name" value="NAGS_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010167">
        <property type="entry name" value="NH2A_AcTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30602">
        <property type="entry name" value="PTHR30602"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00696">
        <property type="entry name" value="AA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000423">
        <property type="entry name" value="ArgA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53633">
        <property type="entry name" value="SSF53633"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01890">
        <property type="entry name" value="N-Ac-Glu-synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5 8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="4 8" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="9">
        <location>
            <begin position="290"/>
            <end position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC92327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="436" mass="48015" checksum="681F905F235E20E2" modified="2018-07-18" version="1">MENAEQFVQWLRSVAPYIHAFRGKTFVVAFPGELVVAGVLPFLAEDLSLLHALGIKIVIVHGSRPQVAEQLALRNVEGRFHNGIRITDTAALECSKEAAGELRLDIEAAFSQGLPNTPMAHSEIRIISGNFVTARPIGIVNGIDYGLTGMTRKIAYDTIHRILDTGNLVLLSPLGFSPTGEAFNVTMEDVAVSAATSLNADKLIFITETPMLCDQDGDELRELSSQQAKAELAANYLPTDSSFYLEHGVKATNAGVPRVHIVPFNLDGSALLELFTHDGVGTMITYENLESLREATIDDIGGIINLIEPLEADGTLVKRGRELIEREINNFSVIEHDNVIFGCAALYAFPADGMAEMACLTVNPDVQSQGDGERILKHMEKRARRAGFSKLFVLTTRTAHWFLKRGFVTATVDDLPKDRQRMYNWQRKSIVLIKQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXB1</accession>
    <name>A0A2S9GXB1_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ribonuclease VapC</fullName>
            <shortName evidence="5">RNase VapC</shortName>
            <ecNumber evidence="5">3.1.-.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Toxin VapC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">vapC</name>
        <name evidence="7" type="ORF">S2091_3007</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Toxic component of a toxin-antitoxin (TA) system. An RNase.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the PINc/VapC protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="5"/>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92348">
        <property type="protein sequence ID" value="PRC92348"/>
        <property type="gene ID" value="S2091_3007"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004540">
        <property type="term" value="F:ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090729">
        <property type="term" value="F:toxin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00265">
        <property type="entry name" value="VapC_Nob1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002716">
        <property type="entry name" value="PIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022907">
        <property type="entry name" value="VapC_family"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01850">
        <property type="entry name" value="PIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00670">
        <property type="entry name" value="PINc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="SSF88723"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 5" id="KW-0540">Nuclease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0800">Toxin</keyword>
    <keyword evidence="1 5" id="KW-1277">Toxin-antitoxin system</keyword>
    <feature type="domain" description="PINc" evidence="6">
        <location>
            <begin position="2"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="7"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="97"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC92348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="134" mass="15050" checksum="660AF1F55CCF5ABC" modified="2018-07-18" version="1">MARYMLDTNICIYLMKNQPEQVARRFAQCYVGDVVISAITFAELEYGISASPNSTQERRNLSELIEDIPVMPFDIAAATAYGPIRKATQERKKDHLDKLIAAHATSLGVILVTNNERDFSSYPGITIENWVNPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXB8</accession>
    <name>A0A2S9GXB8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Crp-like helix-turn-helix domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2965</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92306">
        <property type="protein sequence ID" value="PRC92306"/>
        <property type="gene ID" value="S2091_2965"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012318">
        <property type="entry name" value="HTH_CRP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13545">
        <property type="entry name" value="HTH_Crp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="SSF51206"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51063">
        <property type="entry name" value="HTH_CRP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH crp-type" evidence="2">
        <location>
            <begin position="179"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="280" mass="30896" checksum="2A6982BF201AB71E" modified="2018-07-18" version="1">MNNSSSKTISTNARLAFQSTALLTKTYSSAAGKFTPSPIGATQNDLLASLHPDELAYLLPHLELVKLPLNKELHQHGSEISHVYFPTTAIIASLFLRADGNETEIGVTGHEGLIGTSILMSDRALGTARVQSAGFAYKMDAAILKEVCMHCSKLHDLLMRYMQASFSKMTLISVYENHCTVDQKLARWLLDRLDRSATNVLNVTQEMIATMLCVRRESITEAACRLRNAGLISYLRGIIVVLDRDGLEINAGESYTMAKQEFDLILSDPNSNLRGHMYAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXD8</accession>
    <name>A0A2S9GXD8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">ATP-dependent helicase HrpA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_2985</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92326">
        <property type="protein sequence ID" value="PRC92326"/>
        <property type="gene ID" value="S2091_2985"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011709">
        <property type="entry name" value="DEAD-box_helicase_OB_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007502">
        <property type="entry name" value="Helicase-assoc_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024590">
        <property type="entry name" value="HrpA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010222">
        <property type="entry name" value="RNA_helicase_HrpA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11898">
        <property type="entry name" value="DUF3418"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04408">
        <property type="entry name" value="HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07717">
        <property type="entry name" value="OB_NTP_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00847">
        <property type="entry name" value="HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01967">
        <property type="entry name" value="DEAH_box_HrpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0347">Helicase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="2">
        <location>
            <begin position="46"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="3">
        <location>
            <begin position="240"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="970"/>
            <end position="1000"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC92326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="1283" mass="144612" checksum="A36A3D428286D277" modified="2018-07-18" version="1">MTIPTKPAQRSPAKPPVKSEPPFRNPLPPITFPEELPVSGKRDEIARAIRDNQVIILCGETGSGKTTQLPKICLELGRGTAGLIGHTQPRRIAASSTAKRLAQELGSELGVHVGFKVRFTDTLSKGASIKLMTDGILLAETQGDPLLKQYDTIIIDEAHERSLNIDFLLGYLKQLLPKRPDLKVIITSATIDANRFAQHFGSENKPAPVLEISGRLYPVELRYRPVQEGEKDKDRDLMTAITDAVDELCRLGSGDVLVFLPGEREIRDAAEALRKHHPAHVEILPLFARLSAQEQEKVFKSTNARRIVLSTNVAETSLTVPGIRFVVDTGLARVKRYSYRNKVEQLQVEPIAQSAANQRSGRCGRVAAGVCIRLYEEQDFNARLPFTEPEILRSSLAAVILRMRSLHLGDVERFPFIEAPQGRAIADGYQLLQELGALDEENKLTPLGVKLAKLPLDPRIGRMILAAVEQHSLDEVLIIAAALSVQDPRDRPMEAQAAADLAHKKFADEKSEFVSYLKMWSWFEDAILHKKSNRLLQQNCRENFLSQLRLREWREVHSQLLTIVKEQGWRLNETPATYEQLHTSLLTGLLGNLGFKGEEATQYLGARAIKFNIWPGSNLVKKAGRWIMAAELVDTSRLYARCIAQIQPEWLEKIGAHLLRKNVSEPRWEKRANQVSAFERATLYGLVVYSQRRIQYGLTHPEDAREIFIRDALVAGEFDTRAPFFAHNQKLLREIENLEHKSRRVDVLVDDSLIIAFYDQHIPAGIFNGITFEKWHKEATLKNPKLLYLQRDDLMRHEAAGVTTDVFPKVMAQAGTDLQLSYHFEPGSPRDGVTLTVPLFALNQITMDRCDWLVPGMLKEKVQLLLKSLPQKIRRHCVPIPDYAAGFCSRAKFGEGNFLEALMADIRDQTGLQTKPSDFKFETIPAHLVMNFKIIDEHGRQLEMGRNLATLRVELGGSARESFQKLVQEKSAGLQATTTTKPASVDPKSNTKTAEASAPAGAIQSDNLTAWTFGELPELLEIAQGKQTLIGYPALVDKASCCQLQVFDDPEVAAKVHRTGLIRLFALQLKEQLKFLEKNIPGLQQMGMQFMSLGSQEELRTQIIELAFERAFLQQPLPKNAEQFMQRKEEGRPRLNLLANEIARLAGVILAEYYSLPKKLQGIKSPATTDMLAQLQALVGKRFILETPYTQLVHYPRYLKAITVRMDKMRADPARDTRLMQEWAEAASGWQRTSSQAKSSDVKLQEYRWMLEELRVSLFAQELKTPMPVSAKRLQKVWESLQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXG4</accession>
    <name>A0A2S9GXG4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative NAD(FAD)-dependent dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_2787</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92412">
        <property type="protein sequence ID" value="PRC92412"/>
        <property type="gene ID" value="S2091_2787"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016156">
        <property type="entry name" value="FAD/NAD-linked_Rdtase_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004099">
        <property type="entry name" value="Pyr_nucl-diS_OxRdtase_dimer"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02852">
        <property type="entry name" value="Pyr_redox_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55424">
        <property type="entry name" value="SSF55424"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyr_redox_2" evidence="3">
        <location>
            <begin position="7"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="domain" description="Pyr_redox_dim" evidence="2">
        <location>
            <begin position="333"/>
            <end position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC92412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="449" mass="48432" checksum="555278F8B0CE7926" modified="2018-07-18" version="1">MNKITTNYLILGANASGLSAAVRILKSDKQAKITVLEKSDVVSFGSCGIPYYVAGEFDDINQMTARPLEDFIKLGIDVRLFHTAIGLDPLNKQVTAHNGNTNQSVSLAYDKLFIAVGASPTTPPIKGLAAKNIHTMHSKADAITILNLLPEIQHVVIIGAGFIGMEAAEAFSEQGKNVTVIEFAERVLARTFDAEITPQVEDALQRHSVALQLNESVLEIKHENGAAHSVLTNKDEYPADLVIVATGFKPNTEFLRNTDIKLSKEGAIIIDDQCKTNLPDIYAAGDCATVPHKISGNVYIPLATSANKLGRIAGDVMAGKDSRFIGTLGSSGVRVFDVEAGRTGITEEEAKQLGIDYGTVVIKDKNQTDYVPGQSDMWVKLIYEQQSRKLLGGQVCGRYLGGAVHRVDALAVAVYSGLTVEELGFMDFIYAPPFARTWEILNIAGNVAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXJ4</accession>
    <name>A0A2S9GXJ4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">CHRD domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2822</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92447">
        <property type="protein sequence ID" value="PRC92447"/>
        <property type="gene ID" value="S2091_2822"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010895">
        <property type="entry name" value="CHRD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07452">
        <property type="entry name" value="CHRD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00754">
        <property type="entry name" value="CHRD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50933">
        <property type="entry name" value="CHRD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015655578" evidence="1">
        <location>
            <begin position="33"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="domain" description="CHRD" evidence="2">
        <location>
            <begin position="31"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="146" mass="15031" checksum="F2B47E4F6DD1B960" modified="2018-07-18" version="1">MNKYNYQNHVTSMLKILLLGCFLAVGVGATNAATTQLTLVGAAETPPVKTSATGTGSITVNADKTVSGSVTTTGLVGTVAHIHLGAEGKKGPVIILLTKSGENSWSVPSGSILTDAQFASYKAGNLYVNVHTAKNMDGEIRGQLMP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXV8</accession>
    <name>A0A2S9GXV8_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">TGc domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2596</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92541">
        <property type="protein sequence ID" value="PRC92541"/>
        <property type="gene ID" value="S2091_2596"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021878">
        <property type="entry name" value="TgpA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002931">
        <property type="entry name" value="Transglutaminase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11992">
        <property type="entry name" value="TgpA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01841">
        <property type="entry name" value="Transglut_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00460">
        <property type="entry name" value="TGc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="SSF54001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="16"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="65"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="111"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="135"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="168"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="570"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="domain" description="TGc" evidence="2">
        <location>
            <begin position="419"/>
            <end position="490"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="679" mass="76197" checksum="915019E4ADE4173D" modified="2018-07-18" version="1">MTSLIQRIAALPRDKTDALLLIFACAMVLLPFTEHSPTWINAIAGLLIAWRVWITLRGQVMPKKWLLTLISALLLTAVYLHFHTWLGKDAGIAFLIVLACLKMLEMHARRDAVAVIFASYFLLVGQLLYSQSLLTAMYLLLCICLLISAQLTFQYYQLTPSFPKRLASGFKIVGLAIPLALIFFLLFPRIQGPLWGKQQGNSGGITGLSDSMEPGNVAELALSDQIAFRVKFLGTTPAPSQLYWRAIVLDTFNGKRWSASSVSAPAQQESTPPAHGRQVTQEIIMEPHNQRWLFGLDRPTSITGSTELNSTLTRYWEMRSSSPIQERIRYTITSNLSNTANMNTAPPASLSERMAAERQSLLLPNGYNPLTLQWAQQFRQKSTDPAQLANLVLRFFREQPFRYTLAPPPLGVNQVDDFMFGTQAGFCEHYASAFVVVMRAMGIPARVVTGYQGGEVNPIDGLMTVRQSDAHAWAEIWLEAHGWVRFDPTAAVAPNRVEHGLNGSFPNRNFSNLLNFNQQTWLSNLAKEARLRWDATNSAWNLWALNYNLDKQKNLLSTLSGIEHPQATQLGVAMMIAASLVVAALSLLLLGKKTVHSPLDKLYITFCQYMSRQGYPRMQHEGARDYGQRLQLVFHNKKELADFLTLYTKCKYGKSYNSSHILTLKMLLKLCLQLKPSPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXZ2</accession>
    <name>A0A2S9GXZ2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative Zn-dependent protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_2649</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase U62 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92594">
        <property type="protein sequence ID" value="PRC92594"/>
        <property type="gene ID" value="S2091_2649"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045569">
        <property type="entry name" value="Metalloprtase-TldD/E_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045570">
        <property type="entry name" value="Metalloprtase-TldD/E_cen_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002510">
        <property type="entry name" value="Metalloprtase-TldD/E_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035068">
        <property type="entry name" value="TldD/PmbA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036059">
        <property type="entry name" value="TldD/PmbA_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01523">
        <property type="entry name" value="PmbA_TldD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19289">
        <property type="entry name" value="PmbA_TldD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19290">
        <property type="entry name" value="PmbA_TldD_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111283">
        <property type="entry name" value="SSF111283"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PmbA_TldD" evidence="2">
        <location>
            <begin position="31"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="domain" description="PmbA_TldD_M" evidence="4">
        <location>
            <begin position="122"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="domain" description="PmbA_TldD_C" evidence="3">
        <location>
            <begin position="236"/>
            <end position="447"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01523"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF19289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF19290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC92594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="448" mass="48084" checksum="2D7146498B567710" modified="2018-07-18" version="1">MSVFTYSQDQLKQLAQDVLRFSRDKGATDAAVEISEGSGLSVGVRRGKIETIEQNKDKGIGVTVFIGQQRGNASTSDFSAAALQATVDAAYNIARFTAADDCAGLPDADMLEMHPKELKLFYPWKISAEEAITLAKRCEAAAFEVDPRIKNSEGAGVYAHQSHFVAANSIGFMGGYASSRHSISVSPIAGRGANMQRDYWYSSARNAKKLAQPEAIGHYAAERALSRMHARKLTTRKCPVLFEAPLAVGLVGALVQAVSGGALYRKSTFMLDSMGKTVFPKHIQLSEDPYILGATGSSPFDGEGVKTQKRDVVKNGVLQGYFLSTYSARKLGMKTTGNSGGSHNLSFKSSLTKPRDNFSAMLKKMGTGLLVTELMGQGVNYMTGDYSRGASGFWVENGVIQYPVEEITIAGNLAEMFQQIVAVGADTLTRGTKQTGSILIESMTVAGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GY20</accession>
    <name>A0A2S9GY20_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8 9">2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase</fullName>
            <shortName evidence="8">MECDP-synthase</shortName>
            <shortName evidence="8">MECPP-synthase</shortName>
            <shortName evidence="8">MECPS</shortName>
            <ecNumber evidence="4 8 9">4.6.1.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">ispF</name>
        <name evidence="11" type="ORF">S2091_2655</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 9">
            <text>4-CDP-2-C-methyl-D-erythritol 2-phosphate = 2-C-methyl-D-erythritol 2,4-cyclic diphosphate + CMP</text>
            <dbReference type="Rhea" id="RHEA:23864"/>
            <dbReference type="ChEBI" id="CHEBI:57919"/>
            <dbReference type="ChEBI" id="CHEBI:58483"/>
            <dbReference type="ChEBI" id="CHEBI:60377"/>
            <dbReference type="EC" id="4.6.1.12"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
        <text evidence="8">Binds 1 divalent metal cation per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via DXP pathway; isopentenyl diphosphate from 1-deoxy-D-xylulose 5-phosphate: step 4/6.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homotrimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8 9">Belongs to the IspF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.6.1.12" evidence="4 8 9"/>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92600">
        <property type="protein sequence ID" value="PRC92600"/>
        <property type="gene ID" value="S2091_2655"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00056">
        <property type="reaction ID" value="UER00095"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008685">
        <property type="term" value="F:2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019288">
        <property type="term" value="P:isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016114">
        <property type="term" value="P:terpenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00554">
        <property type="entry name" value="MECDP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00107">
        <property type="entry name" value="IspF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003526">
        <property type="entry name" value="MECDP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020555">
        <property type="entry name" value="MECDP_synthase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036571">
        <property type="entry name" value="MECDP_synthase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43181">
        <property type="entry name" value="PTHR43181"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02542">
        <property type="entry name" value="YgbB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69765">
        <property type="entry name" value="SSF69765"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00151">
        <property type="entry name" value="ispF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01350">
        <property type="entry name" value="ISPF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8 9" id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword evidence="7 8 9" id="KW-0456">Lyase</keyword>
    <keyword evidence="5 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YgbB" evidence="10">
        <location>
            <begin position="8"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="4-CDP-2-C-methyl-D-erythritol 2-phosphate binding" evidence="8">
        <location>
            <begin position="15"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="region of interest" description="4-CDP-2-C-methyl-D-erythritol 2-phosphate binding" evidence="8">
        <location>
            <begin position="41"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="4-CDP-2-C-methyl-D-erythritol 2-phosphate binding" evidence="8">
        <location>
            <begin position="63"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="4-CDP-2-C-methyl-D-erythritol 2-phosphate binding" evidence="8">
        <location>
            <begin position="68"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="4-CDP-2-C-methyl-D-erythritol 2-phosphate binding" evidence="8">
        <location>
            <begin position="107"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="15"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="17"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="49"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="149"/>
        </location>
        <ligand>
            <name>4-CDP-2-C-methyl-D-erythritol 2-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:57919"/>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="8">
        <location>
            <position position="41"/>
        </location>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="8">
        <location>
            <position position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012579"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC92600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="164" mass="17628" checksum="4A235B6BCF1D1244" modified="2018-07-18" version="1">MKNSLPNFRIGQGYDCHALVENRKLIIGGVTIPHKTGLLGHSDADVLLHAITDALFGAAGLGDIGRHFPDTDMQFSGADSRVLLREAVKRVEVAGFLVGNLDATIIAQAPKMAPHIPSMVEHIAQDLQVAVDRINIKAKTNEKLGYLGREEGIAAEAIVLIYAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GY26</accession>
    <name>A0A2S9GY26_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Reverse transcriptase (RNA-dependent DNA polymerase)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2680</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92625">
        <property type="protein sequence ID" value="PRC92625"/>
        <property type="gene ID" value="S2091_2680"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003964">
        <property type="term" value="F:RNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000477">
        <property type="entry name" value="RT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00078">
        <property type="entry name" value="RVT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="SSF56672"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50878">
        <property type="entry name" value="RT_POL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0695">RNA-directed DNA polymerase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Reverse transcriptase" evidence="1">
        <location>
            <begin position="140"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="431" mass="48983" checksum="2F29E6FEACF6D8E2" modified="2018-07-18" version="1">MINKGDFLESPAMRSFGAATGIRTTMPASSISTTTVLTTRTTTSASADPIISRLGTEHAHVKPTIIGRKSPGDTPKARQFAKPKTVAGLTSAATEGGNESIFHQLTSLDSLYQYWLKAKKNKSKSLRVQRFGDDPLRYLVMIQNRLRDREYTFGPYKSFTVREKKFRHVVDAPMKDRVVHWMLYDYLLPIWQPRFIHDTYGNLPRRGTHAAVNRLAQFCRGADSKWVLQLDISKYFYSVNHEILKARALRFIGDHDLRVLMIALIDSFATDSQYDDLFPADGMYRTTAAKGMPIGNLSSQLFANIFLNDFDHWVKEVLRIKLYIRYVDDMVILADSKEELATIRDLIVQKLALDGLTIHPKKIRLAPATAGIPFLGYIVWPNHISAGSYVRGRYLHRVRQHERDGYDKTEALAAYSAMFKHTGSTIYREAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GY51</accession>
    <name>A0A2S9GY51_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">LysR substrate binding domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2693</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92638">
        <property type="protein sequence ID" value="PRC92638"/>
        <property type="gene ID" value="S2091_2693"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="303" mass="33484" checksum="47FDCEF457142EFB" modified="2018-07-18" version="1">MYDLEIILAIAKSDSFKTAMLKLCLSKSTFSDRLKKIENSLGVKIVTRSGPFGLTKAGEIALKHANQMLASDENMRKELASLTDSPALRIVSSPALLIADAVPAIGSLLKENENMRVATEPMRHTEVFGEVLSGAADIGLIPTKPLVAGLVLIEYKTEPLVVVANHKHPINRRGLKQISFIEALEYDFVTDITQGEINGLMHEAALANGKSVNIRASTGTAEMQSELVKHSIGIAVMPMSTARRYFQARYIRLTDAWTNLSFSICLRESDFENENHQNFIKIIKKKYGEAKSYPQADLLQKHT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GY58</accession>
    <name>A0A2S9GY58_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2709</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92654">
        <property type="protein sequence ID" value="PRC92654"/>
        <property type="gene ID" value="S2091_2709"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010774">
        <property type="entry name" value="YbcO"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07102">
        <property type="entry name" value="DUF1364"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="110" mass="12366" checksum="6EC17295BFC899D5" modified="2018-07-18" version="1">MKRSRMKSSRPKTTKIRQSARMQDCTFRFPAICNYNPETTVWCHSNEIEDGKGAGLKARDEEGAYGCSACHAFYDGGYVNHDVDRGYVRAGFNVARAISQKILKLKGLMP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GY85</accession>
    <name>A0A2S9GY85_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">P22 coat protein-protein 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2723</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92668">
        <property type="protein sequence ID" value="PRC92668"/>
        <property type="gene ID" value="S2091_2723"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024659">
        <property type="entry name" value="Phage_coat_Gp5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11651">
        <property type="entry name" value="P22_CoatProtein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0167">Capsid protein</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0946">Virion</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="388" mass="40329" checksum="A371E5DFC8A30DAB" modified="2018-07-18" version="1">MANNLNGLIPTLYQALDIVSREVVGFIPAVAKNSNGEKAAVNEIISIPQTTQGGLIDIVPGAIAGTGGSQTVAPLNMTISKSKAYEVLWNGEEQKGMNNAGTYNGVLMNQFTQGFRTLANAVEADLALCGFSASRAYGTAGTTPFGNAGDLSDFAQSRKILIDNGAPMSDLHMVMNTAAAANLRGKQSSLFKVNESGTEILLRTGSIAMPVDGFFPHESGQIQTFTKGTGSAYTTDTASYAVGATVINLIGGSGTVLAGDVVSLAGDTNKYVVAVGTAAPGPITLQAPGLRQAIPAVATALTTGASYTANLAFDRNAIQLITRSPAMPMGPDGKAIDMAEDVIELQDPVTGIVFQIAMYKMYRQVKYEIGLAWGTKAIKPNHMAILLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYE8</accession>
    <name>A0A2S9GYE8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NACHT domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2474</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92744">
        <property type="protein sequence ID" value="PRC92744"/>
        <property type="gene ID" value="S2091_2474"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13401">
        <property type="entry name" value="AAA_22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="1">
        <location>
            <begin position="271"/>
            <end position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="887" mass="101880" checksum="CEC6E7AC9678403F" modified="2018-07-18" version="1">MTPTIKPTQLTRVGYTYQDYVCLKLLIEWFHNPEKYHWVSIEGASTEDGLWAIDDVVALDKNGKYTLLQVKFTIDSERNDLKLDFDWLLNHRPAGTSLLQKWSRDVKKYSDAGRIAFAALKTNRIPGDEFEKCLEYGKINIDKIPAEWLEKIIEQIGSYENAKSFFLEFTFDHSQQEIRDLHNHLYNQIVPDHATPEGWYRLLEAVECWATHKNEPSPDGQITLSHIYEILNSGIRESLPQFFEVPPGYSPPTGQFHAGMLQRTKLTGGWVISGLPGMGKSTYLSYLTTQLTIQKIPVIRHHYSISTQDFVDRTNYFNVARSLQHQLQLHYPKLFFARELDGNKLEDWLRTAADYSHSIGINLVLIIDGLDHVSRERKEISQLEHLINRLLPFKDRLCLIFGTQPIRDTDLPSRLIAEIPKNDRWLNLPAMDLSSIKCWLEALSDSNRIALNNYGGDKSGGLVEASEALLMASGGYPLHMTYSLQSLTLLGKTINKYEIGKLPPCPAGDIRLYYDALWSNLSEAARTILLLIACVDFPWPDKKSIGSCFENSLEFLESYSKIQHLVEKRRSGVFPFHSSIMVFLREQQGFKDLYTELLRKAKTWLEKDAPKYWQWGWKWIVEAHLGNTEFLTTGINREWLVDSFCNGYPLQHIEHIFSVAEQISSENKNYPELVRLRLLKIRLINGPEFQIQEYPQFMNCALSWNEEKYGMLWGADNLRTLDDKEISVISSLFREVDDAVCIDCFKEIIRRLEFYAKIGGGSENQKIDLLINAAIDVLCDRKNPSADEILAFLGRITEKIPLYPRVFDRLIETGNWHVILDFSVSKLPSEVVDLFWNYFVLACKIENVSIIERPERSSIASSVFGNIVLALIEPDGPPNPPPVACHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYJ5</accession>
    <name>A0A2S9GYJ5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2527</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92797">
        <property type="protein sequence ID" value="PRC92797"/>
        <property type="gene ID" value="S2091_2527"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="59" mass="6263" checksum="BB6BA77427BEED32" modified="2018-07-18" version="1">MNDIKKNDVDNKDDKKVGLDVSDITFDKNGEIIGLSDDVLDSITGGLSVTNSCGGNMQC</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYL8</accession>
    <name>A0A2S9GYL8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">GGDEF: diguanylate cyclase (GGDEF) domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_2533</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92803">
        <property type="protein sequence ID" value="PRC92803"/>
        <property type="gene ID" value="S2091_2533"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01948">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001633">
        <property type="entry name" value="EAL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035919">
        <property type="entry name" value="EAL_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00563">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00052">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141868">
        <property type="entry name" value="SSF141868"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50883">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="213"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="2">
        <location>
            <begin position="246"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="3">
        <location>
            <begin position="321"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="5">
        <location>
            <begin position="405"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="domain" description="EAL" evidence="4">
        <location>
            <begin position="552"/>
            <end position="805"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC92803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="805" mass="90895" checksum="C730C908F2161D6F" modified="2018-07-18" version="1">MPKKLAMRNTTISHVYLIIAMFVAMIITLTFLMQIQMNALMAVRAYIGGAGVWAKAQKEAILSLEHYALTHDENDYQNYQRSIQIPIGDLQARIALQKPNPDLAMAREGFLIGGNHPEDIESMSDLFLRFQNFSFMTEVIKSWTTGDKLIAELNEEAEKLHQDISSHSINSDTVHTFMIRTNIINQHLTEQENLFSSTLATISRSASHASRNFSYTIALLFTLLGVGISWTIIARIRAIDTVLHNSEAYLRIAATAFESQENLIITDANEVILRVNKAFTENTGYSAEEIIGQTPRLLKSGRHPPEFYKEMWETIQLKGAWQGEIWGRRKNGQIYPKWLSISAVKGAGGHITHYIGSYIDITERKEAEEKIKYIAFHDHLTNLPNRRLLLDRLQQALTSNARSGRKGALLFIDLDNFKDLNDTLGHDTGDLLLQQVAQRLEASFRENDTVSRMGGDEFVVMLLDLSEHHMEAATQTELIGEKTLAILSQPYQLDKYELTCTASIGITLFDGNDQMKDELMKQADIAMYQAKKAGRNTLRFFDNQMQDAITIRTKLDTELHKALESQQFQLYYQIQVDNARRPIGAEALIRWQHPTRGVVFPGEFIALAEETGLILPIGKWVLDTACAQIKAWQNDASTQALVLAVNVSANQFRQADFVSQVQTCVQLHAINPMLLKLELTESLMLKDVDDTIVTMNSLKEIGVQLSLDDFGTGYSSLQYLKRLPFDQIKIDRSFVRDIATDPNDAAIVQTIIAMAKTLGLNVIAEGVETEEQREFLNLRGCYAYQGYLFGKPVPLEQFEAMLELA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYR3</accession>
    <name>A0A2S9GYR3_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Type II secretion system protein N</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">General secretion pathway protein N</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">S2091_2282</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GSP N family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92865">
        <property type="protein sequence ID" value="PRC92865"/>
        <property type="gene ID" value="S2091_2282"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015627">
        <property type="term" value="C:type II protein secretion system complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015628">
        <property type="term" value="P:protein secretion by the type II secretion system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022792">
        <property type="entry name" value="T2SS_protein-GspN"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01203">
        <property type="entry name" value="T2SSN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="24"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00030772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC92865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="275" mass="29363" checksum="32667833CC263CD9" modified="2018-07-18" version="1">MSRFEQHDLPGNKTANKLSLKQKIVCICLGLLGMLLTVMAFAPAVWLSTLLEMQTDGRFALGDAQGSLWNGSAFIGVAATKNGDLTPLLPGRFAWHLSPILLLGQIELGLENSAALQQPLHITGNLRHVQVSPGGLILPAERLSGLGAPLNTVKPSGKMTLSWDALGVTLSEGKVDINGTMKLQMQDIASALSPIKPLGSYLMNFVWHGQQADIELKTLQGPMLLSGKGALVQGRLQFSGSAQAQEGQEDKLANLLNLLGQRRAGTDKNVIALEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZ22</accession>
    <name>A0A2S9GZ22_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Transcription termination/antitermination protein NusA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">nusA</name>
        <name evidence="9" type="ORF">S2091_2293</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Participates in both transcription termination and antitermination.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the NusA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92876">
        <property type="protein sequence ID" value="PRC92876"/>
        <property type="gene ID" value="S2091_2293"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006353">
        <property type="term" value="P:DNA-templated transcription, termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031564">
        <property type="term" value="P:transcription antitermination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1480.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00945_B">
        <property type="entry name" value="NusA_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010995">
        <property type="entry name" value="DNA_repair_Rad51/TF_NusA_a-hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025249">
        <property type="entry name" value="KH_dom_NusA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009019">
        <property type="entry name" value="KH_sf_prok-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030842">
        <property type="entry name" value="NusA_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036555">
        <property type="entry name" value="NusA_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022967">
        <property type="entry name" value="S1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013735">
        <property type="entry name" value="TF_NusA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010214">
        <property type="entry name" value="Tscrpt_termin_fac_NusA_C_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010213">
        <property type="entry name" value="Tscrpt_termination_fac_NusA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22648">
        <property type="entry name" value="PTHR22648"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13184">
        <property type="entry name" value="KH_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08529">
        <property type="entry name" value="NusA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00575">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47794">
        <property type="entry name" value="SSF47794"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54814">
        <property type="entry name" value="SSF54814"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69705">
        <property type="entry name" value="SSF69705"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01953">
        <property type="entry name" value="NusA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01954">
        <property type="entry name" value="nusA_Cterm_rpt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6 7" id="KW-0804">Transcription</keyword>
    <keyword evidence="3 7" id="KW-0889">Transcription antitermination</keyword>
    <keyword evidence="5 7" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="1 7" id="KW-0806">Transcription termination</keyword>
    <feature type="domain" description="S1 motif" evidence="8">
        <location>
            <begin position="138"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC92876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="519" mass="57682" checksum="D060F8C865FEE9B0" modified="2018-07-18" version="1">MSREVLLLVDALAREKNVDKEIVYGALEHALAQATKKRYEGDVDIRVTIDREGGQFESFRRWHVVPDDAGLQLPDQEILHFEAMEQYPDIEVDEYIEEAIESVDFGRRFAQDAKQVMLQRVRDAEREQILADFLERGDSLVTGTIKRMERGEAVVESGKIEARLPRDQMIPKENLRIGDRVRAYILRIDRNARGPQVILSRTAPEFIMKLFELEVPEIEQGSLEVKSAARDPGVRAKIAVHTNDPRIDPIGTCVGMRGSRVQAVTGELGGERVDIVLWSEDPAQFVIGALAPANVSSIVVDEEKHAMDVVVDDENLAIAIGRSGQNVRLAAELTGWQINIMTAEQSADKSELETSAIRALFMQKLDVDQEVADILVDEGFASLEEIAYVPISEMLEIEALDEDTVNELRNRARDAIVSEAIASEEGVDGVEDALINLPGMDRVTAGKLGLAEVKTLSAFAGLAYDEFGAILALSAERARQLIKNEFDDVTDDEMKLIDAKYDDRAKAILAKAWSITETK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZ56</accession>
    <name>A0A2S9GZ56_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">OmpA family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_2431</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC93014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93014">
        <property type="protein sequence ID" value="PRC93014"/>
        <property type="gene ID" value="S2091_2431"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07185">
        <property type="entry name" value="OmpA_C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025511">
        <property type="entry name" value="DUF4398"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006664">
        <property type="entry name" value="OMP_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006665">
        <property type="entry name" value="OmpA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006690">
        <property type="entry name" value="OMPA-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036737">
        <property type="entry name" value="OmpA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14346">
        <property type="entry name" value="DUF4398"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00691">
        <property type="entry name" value="OmpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01021">
        <property type="entry name" value="OMPADOMAIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103088">
        <property type="entry name" value="SSF103088"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01068">
        <property type="entry name" value="OMPA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51123">
        <property type="entry name" value="OMPA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1 3" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015610290" evidence="5">
        <location>
            <begin position="20"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="domain" description="OmpA-like" evidence="6">
        <location>
            <begin position="159"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="130"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC93014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="282" mass="30892" checksum="D25FA9041AAD67C3" modified="2018-07-18" version="1">MKKNLFSPTLLTIAVLISACSTVPRTTSFLEQTRRDYGVAQNNPNVARYAPLEMQQATIAMNQANLASTHDDSEDKINKLAYIAKDKIALAQEVTKQKLAEVAMASTVKERDQMVLNQRTAEADQAKMNAADSQRKTQEAQAHAAQLEAELADLAAKKTDRGMVITLGDVLFGTDLSRLNSNGMHTAQKLADVLNQNPQRTVLIEGFTDSTGTAPYNQELSERRAKAVRSALQDMGIAAERIAIRGYGQDFPVASNDTAGNRQMNRRVEIVLSDDNGKIAQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZ70</accession>
    <name>A0A2S9GZ70_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2343</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92926">
        <property type="protein sequence ID" value="PRC92926"/>
        <property type="gene ID" value="S2091_2343"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="123"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="389" mass="44881" checksum="267775949498385C" modified="2018-07-18" version="1">MLIGFFFTLKDAKIPVSIKEFLMLLEALQKNIASTSLDDFYFLARIIMVKDEAHFDKFDKAFGLYFKGIDAIFEKHPEIPLDWLKKRLERELTDEQKAAIEKFGYDKLMDRLSELLKEQKERHEGGNKWIGTGGTSPFGHGGTNPEGIRIGGKGGKRSAVKVWEARAYRDYDTERELGTRNIKVALRRLRKFARHGVAEELALDATIQATAHNAGYLDIKMQPERKNNIKVLMLLDVGGSMDDHIARTEELFSAAKTEFKNMEFFYFHNCVYDYLWKNNQRRHAEKIPTWDILRKYPADTKLILVGDATMSPYEVLQPGGSVEYNNEEAGATWLQRLTNTFPKHIWLNPEPEGLWEYRQSIAVIRQLVSNHMFPVTIEGLERGMQLLSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZ75</accession>
    <name>A0A2S9GZ75_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2121</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93035">
        <property type="protein sequence ID" value="PRC93035"/>
        <property type="gene ID" value="S2091_2121"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="101" mass="11275" checksum="AA70ABBC73E227C8" modified="2018-07-18" version="1">MDKQSDLGRELTCPTQRIQYRDQAIGENMNTATLNIPTGAALEREIDNAEAQLHDELIRKTISERMAIANDQQTVFVTHENAFTASQARLLSKLAGNFNAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZC1</accession>
    <name>A0A2S9GZC1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2168</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93082">
        <property type="protein sequence ID" value="PRC93082"/>
        <property type="gene ID" value="S2091_2168"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="55" mass="5929" checksum="5C042F4ACFA5A337" modified="2018-07-18" version="1">MKLTKPFLGVPDGQIYPVEYQAGDECPPELIEAAKSLGAIEDKVEAKPKTNVKGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZK6</accession>
    <name>A0A2S9GZK6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2224</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93138">
        <property type="protein sequence ID" value="PRC93138"/>
        <property type="gene ID" value="S2091_2224"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="23"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="285" mass="31996" checksum="6B4EE54CD9F972F3" modified="2018-07-18" version="1">MPVSDTPYWLQATSDNSLPLIHFVHGNSFPTGTYKVFLDQLQSNYQIRALEMHGHNPAYPVTDCWPELCKELIASLEVSHARHNKPIILLGHSLGGMLSLMVAKMRPELVRCVVMLDSPVVAGWRAKVLHVAKSLNVAVKFPPAKFSLKRREIWPSKEAAFQHFASKDMFAIWPEQVLCDYISFGTELHSEGVTLRFKRDVETAIYCSLPHAINRFCAQPYPVPIGFICGTTSQECSQAGLFHTKKLVGENFDWIEGGHLYPLESPELAAEKAHAMVQKLLAKTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZQ9</accession>
    <name>A0A2S9GZQ9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_1960</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93222">
        <property type="protein sequence ID" value="PRC93222"/>
        <property type="gene ID" value="S2091_1960"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="3">
        <location>
            <begin position="2"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="4">
        <location>
            <begin position="124"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="2">
        <location>
            <begin position="124"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC93222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="220" mass="24396" checksum="73533F02766F9FC4" modified="2018-07-18" version="1">MRILLVEDDTMIGDAMAFALRNAHYAVDWVNDGQLAITAAQTQHYDAILLDLGLPKSDGFEVLRTIRNAGNVTPVLIVSARDAVESRIAGLDLGADDYVLKPFEIGELLARIRAVIRRKSGHSNSLLENGCISLNLVTREATVEGLPVRLSAREYSLLEALLIRPGAILSRQDLEDRLYQWDKEVESNAIEFLIHGLRKKLGPQAIKNVRGLGWMVSKQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZR8</accession>
    <name>A0A2S9GZR8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">40-residue YVTN family beta-propeller repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1959</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93221">
        <property type="protein sequence ID" value="PRC93221"/>
        <property type="gene ID" value="S2091_1959"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011048">
        <property type="entry name" value="Haem_d1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011964">
        <property type="entry name" value="YVTN_b-propeller_repeat"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51004">
        <property type="entry name" value="SSF51004"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02276">
        <property type="entry name" value="beta_rpt_yvtn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015605192" evidence="1">
        <location>
            <begin position="21"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="330" mass="34531" checksum="BB96A9CE27F62951" modified="2018-07-18" version="1">MKFNFKLTALLLALSSTAFAAAPAYKIVDTIAIGGAAKWDYLYVDSEAHRLYVTHGTQTEVIDTQTNKVVGTIANTQGVHGVAIARELGIGFTSDGVTDSVSVFDLATLKVSSSIKVGTKPDAIVYAPVSQKLVAFNGKSNNASIIDAKTLKVIATVAVAGKPEFAVVGADGNVYFNLEDVGQISSINLATNTVSQTHSLKPCEEPTGLAMDDKQHLFSVCANNLMMVSTTSGKVIAQPAIGSGPDGVAFMDGYAFSANGADGNMTVVGEVNGKFQAVATIPTQVGARTIAADPATHRLYLPTADFKAAQGTEKRQGIPDTFRVLVLQQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZX1</accession>
    <name>A0A2S9GZX1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Plasmid stabilization system protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2020</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93282">
        <property type="protein sequence ID" value="PRC93282"/>
        <property type="gene ID" value="S2091_2020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2310.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007712">
        <property type="entry name" value="RelE/ParE_toxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035093">
        <property type="entry name" value="RelE/ParE_toxin_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05016">
        <property type="entry name" value="ParE_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-1277">Toxin-antitoxin system</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="98" mass="11001" checksum="158425D9DD492D11" modified="2018-07-18" version="1">MARLIYSQIALRDLEKLTDFLLETDPLAATETVELIEEAVVILKHHPLIGRLVELDLRELVISRGKTGYIALYSFEVDQNAVLILAIRHQREAGYAGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0E7</accession>
    <name>A0A2S9H0E7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1838</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93451">
        <property type="protein sequence ID" value="PRC93451"/>
        <property type="gene ID" value="S2091_1838"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="272" mass="30695" checksum="7665843AE2041D8C" modified="2018-07-18" version="1">MTRRTRHMLQEQFLQGKMPTEEDFSDLIGSMLNMLDEGFDKTPEAGFKVAQLRDGKLMSFYKDINIGSPLWSFGLGKSNDNLSILDARNQALLTLSSITGTDDIHRTAIGIRQINPQHELDVAGCIASYARVGHNGELAVPADGNWYDITDTMTGCQAWEVMAGVGAKDNEGRYALTHAFALNAFNDNGSIDYHQTHFGNKCSRIELRWMSEGPKESFEFKLQMRVGCSYGDDVWIKYHMTQLWLDTLMLESDQKPLRQPSPQYDVKGKVKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0H1</accession>
    <name>A0A2S9H0H1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">cAMP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_1854</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93467">
        <property type="protein sequence ID" value="PRC93467"/>
        <property type="gene ID" value="S2091_1854"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012318">
        <property type="entry name" value="HTH_CRP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018335">
        <property type="entry name" value="Tscrpt_reg_HTH_Crp-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13545">
        <property type="entry name" value="HTH_Crp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00034">
        <property type="entry name" value="HTHCRP"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00419">
        <property type="entry name" value="HTH_CRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="SSF51206"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00042">
        <property type="entry name" value="HTH_CRP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51063">
        <property type="entry name" value="HTH_CRP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="2">
        <location>
            <begin position="38"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="domain" description="HTH crp-type" evidence="3">
        <location>
            <begin position="171"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC93467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="257" mass="29374" checksum="3BEECDC59E73EF50" modified="2018-07-18" version="1">MLQGYQVATSTSQCIEAMPRISERQSRCSGCSLRDLCVPTGLAESEMRRVDHIMSRRRIARGDVLYRMGDKFTNLYAIRLGHFKTHQLSSDGVEQITGFQMAGELLGMDAIGTDRHNCYAVALEDSEVCEIPFDRLEGLFAEIPTLLRHFHRTMSQEITRDQTTMLLLGNMHAEQRIASFLINLSARYKMRGYSSTNFQLRMSREDIGKYLGLTIESVSRLLSKFKKMEWITVDKREIGINDLAQLKQLAMQPVSKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0I0</accession>
    <name>A0A2S9H0I0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1881</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93494">
        <property type="protein sequence ID" value="PRC93494"/>
        <property type="gene ID" value="S2091_1881"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015590966" evidence="1">
        <location>
            <begin position="24"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="190" mass="21291" checksum="0A81ECB7B7D1CF41" modified="2018-07-18" version="1">MKRCLSLITLAICTLTAPHFASAQSAPLPAVVSQLPPHDGQHDFDFNIGTWKANVKRLKNPLTGSSTWIELQGTVTVRKIWGGRAQMDEVELDGPNGHFQMMTLFLYSPGSHQWSERFANSGDGDLSVPMIGEFKSGRGEFYSHEQYKDRYILARQIWSDITADSHRLEQSFSSDGGVTWEPNYVATLTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0I1</accession>
    <name>A0A2S9H0I1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cytochrome c oxidase accessory protein CcoG</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_1864</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93477">
        <property type="protein sequence ID" value="PRC93477"/>
        <property type="gene ID" value="S2091_1864"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1060.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014116">
        <property type="entry name" value="Cyt_c_oxidase_cbb3_FixG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032879">
        <property type="entry name" value="FixG_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009051">
        <property type="entry name" value="Helical_ferredxn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13746">
        <property type="entry name" value="Fer4_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12801">
        <property type="entry name" value="Fer4_5"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11614">
        <property type="entry name" value="FixG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02745">
        <property type="entry name" value="ccoG_rdxA_fixG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="32"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="79"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="153"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="176"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="334"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="5">
        <location>
            <begin position="251"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC93477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="466" mass="53117" checksum="4DAC6485A166D6A6" modified="2018-07-18" version="1">MNNATPKVSVVKMYSAREEIYPRETKGRYASLRWLCVWLTQLVFYGLPWLVWNGRQAVLFDLGTRKFYIFGIVLWPQDFIYLAVLLIICAYSLFLFTAVAGRVWCGFACPQTVYTELFLWIERKIEGARSAQIRLARQPWTLEKIARKTAKHFSWGLLSLWTGFTFVAYFTPANTLLHAVVNAALGPWELFWVLFYSFATYGNAGWMREQVCKYMCPYARFQSAMFDKDTLIITYDQKRGEPRSAYPQKDIKAGKEVGACIDCSMCVQVCPTGIDIRKGLQYECIGCAACIDACNSVMTKIDEPLGLIRYSTEHAINNHLTLKEMQQRVMRPRVLIYSGLLVVIIVVFFSTLFMRVPLKLDVIRDRGSLGREVEDGMIENVYRLQIMNTAETAHRFKLSVSGIASITLATPDEVQLDGTASRAVPVRVRVAYGEGKAGSNKIFFELKAVDDSNLHVKERAVFFVPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0K6</accession>
    <name>A0A2S9H0K6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">CcoO: cytochrome c oxidase, cbb3-type, subunit II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_1867</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93480">
        <property type="protein sequence ID" value="PRC93480"/>
        <property type="gene ID" value="S2091_1867"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003468">
        <property type="entry name" value="Cyt_c_oxidase_monohaem-su/FixO"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02433">
        <property type="entry name" value="FixO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00781">
        <property type="entry name" value="ccoO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0349">Heme</keyword>
    <keyword evidence="3 4" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="6">
        <location>
            <begin position="52"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC93480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="204" mass="23370" checksum="2690E1D06E0D9225" modified="2018-07-18" version="1">MKFSHEWIEKNPWLLIGLVVLVISVGGLVEIVPLFFQKSTTEPITGLKPYAPLSLVGRDIYIREGCYNCHSQMIRPFRAETERYGHYSVAGEFVYDRPFQWGSKRTGPDLARVGGRYSDEWHRIHLNNPRDMVPESNMPNYPWLATTKLIPEEVIPKMRALQRLSVPYSDEEIKQAPSALVDKTEQDALIAYLQGLGILIKARN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0W6</accession>
    <name>A0A2S9H0W6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DctP: TRAP transporter solute receptor, DctP family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1591</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93590">
        <property type="protein sequence ID" value="PRC93590"/>
        <property type="gene ID" value="S2091_1591"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030288">
        <property type="term" value="C:outer membrane-bounded periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071702">
        <property type="term" value="P:organic substance transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018389">
        <property type="entry name" value="DctP_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004682">
        <property type="entry name" value="TRAP_DctP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038404">
        <property type="entry name" value="TRAP_DctP_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33376">
        <property type="entry name" value="PTHR33376"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03480">
        <property type="entry name" value="DctP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006470">
        <property type="entry name" value="DctB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00787">
        <property type="entry name" value="dctP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0675">Receptor</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015578552" evidence="2">
        <location>
            <begin position="24"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="334" mass="37643" checksum="E43E9CE8534A9645" modified="2018-07-18" version="1">MLRIRHYALIFMALAMITGSNYAQTTIVIKFSHVVANDSPKGLAAIHFKELAEKMTKGRVRVDVYPNSKLYKDNEELEALQLGVVQMLAPSLSKLSALGFHEFEVFDLPYLFPNKEALHRVTQGPIGRDLLSRLETKNIVGLGIWDNGFKSMSANKPIHTPDDMRGLKMRIQPSKVIATQMRDLGATPLTLSFTYAIDSLRFGLADGTENPPSNFYMMQFIDLQKYLTLTNHGYLGYAVIVNKKFWEDLPAEIRVQLSSAMNETTKFANAMAQQQNELDLAAIRSSGKTTVYELTEAERIQWRKALLPVQQQMETRIGKETLNAVTQEVGNSHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0X4</accession>
    <name>A0A2S9H0X4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1604</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93603">
        <property type="protein sequence ID" value="PRC93603"/>
        <property type="gene ID" value="S2091_1604"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2310.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007712">
        <property type="entry name" value="RelE/ParE_toxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035093">
        <property type="entry name" value="RelE/ParE_toxin_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004386">
        <property type="entry name" value="Toxin_YafQ-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40588">
        <property type="entry name" value="PTHR40588"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15738">
        <property type="entry name" value="YafQ_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006156">
        <property type="entry name" value="YafQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143011">
        <property type="entry name" value="SSF143011"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02385">
        <property type="entry name" value="RelE_StbE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00053">
        <property type="entry name" value="TIGR00053"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-1277">Toxin-antitoxin system</keyword>
    <feature type="active site" description="Proton donor" evidence="2">
        <location>
            <position position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR006156-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="90" mass="10689" checksum="37590B9F52E3BA35" modified="2018-07-18" version="1">MRKPSYSGQFKRDVKLAEKRGKNMNKLRDVIQLLLDGQALPRDFKDHPLQGDWKPRRDLHIEPDWLLIYRIDGDEVRFDRTGTHSDLFGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0Y1</accession>
    <name>A0A2S9H0Y1_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AraC_E_bind domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1618</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93617">
        <property type="protein sequence ID" value="PRC93617"/>
        <property type="gene ID" value="S2091_1618"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.80.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010499">
        <property type="entry name" value="AraC_E-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029442">
        <property type="entry name" value="GyrI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011256">
        <property type="entry name" value="Reg_factor_effector_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06445">
        <property type="entry name" value="GyrI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00871">
        <property type="entry name" value="AraC_E_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55136">
        <property type="entry name" value="SSF55136"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AraC_E_bind" evidence="1">
        <location>
            <begin position="1"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00871"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="155" mass="17029" checksum="F27EA2F702E727C5" modified="2018-07-18" version="1">MKPLIKQVTEFRVAGLAVRTKNCDEFDSSRAKIPALWGTLFATDALNSIPHQPSEPAVFGVYSGYESDASGEYDLTVGALVSAAGHEFSHVAICDGDYLVFEARGAMPAALIQTWGQVWAYFEQHPEQARCYKTDFEQYLGEQAVDVFIGIKKSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H131</accession>
    <name>A0A2S9H131_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">N-acetyl-gamma-glutamyl-phosphate reductase</fullName>
            <shortName evidence="4">AGPR</shortName>
            <ecNumber evidence="4">1.2.1.38</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">N-acetyl-glutamate semialdehyde dehydrogenase</fullName>
            <shortName evidence="4">NAGSA dehydrogenase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">argC</name>
        <name evidence="7" type="ORF">S2091_1668</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>N-acetyl-L-glutamate 5-semialdehyde + NADP(+) + phosphate = H(+) + N-acetyl-L-glutamyl 5-phosphate + NADPH</text>
            <dbReference type="Rhea" id="RHEA:21588"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29123"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:57936"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.2.1.38"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 3/4.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.38" evidence="4"/>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93667">
        <property type="protein sequence ID" value="PRC93667"/>
        <property type="gene ID" value="S2091_1668"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00068">
        <property type="reaction ID" value="UER00108"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003942">
        <property type="term" value="F:N-acetyl-gamma-glutamyl-phosphate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006526">
        <property type="term" value="P:arginine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00150">
        <property type="entry name" value="ArgC_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023013">
        <property type="entry name" value="AGPR_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000706">
        <property type="entry name" value="AGPR_type-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000534">
        <property type="entry name" value="Semialdehyde_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012280">
        <property type="entry name" value="Semialdhyde_DH_dimer_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01118">
        <property type="entry name" value="Semialdhyde_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02774">
        <property type="entry name" value="Semialdhyde_dhC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00859">
        <property type="entry name" value="Semialdhyde_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01850">
        <property type="entry name" value="argC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01224">
        <property type="entry name" value="ARGC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4" id="KW-0521">NADP</keyword>
    <keyword evidence="3 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Semialdhyde_dh" evidence="6">
        <location>
            <begin position="3"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="active site" evidence="4 5">
        <location>
            <position position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC93667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="345" mass="37228" checksum="B0EB62E4B4DDDA37" modified="2018-07-18" version="1">MIKVGIVGGTGYTGVELLRILAAHPEVQLTAITSRKEDGLPVAEMYPSLRGRVALKFSSPDKANLTECDVVFFATPHGVAMAQAPALLAAGVKVIDLAADFRLQDVAQFEQWYGMQHSCADLLKEAVYGLPELNREAIKSARLIGNPGCYPTTMQLGFYPLLKAGIIDADNLIADCKSGVSGAGRKAEISLLFSEASDNFKAYSVAGHRHIPETVEQLQKMSSTPVGLIFTPHLVPMIRGMHSTLYAKLNTTIDNAALQELFEKTYQNEAFVDVMPFGSHPETRSTRGSNTLRIALHRPGNGATLVILVAQDNLMKGASGQAVQCMNLMFGLQETCGLTQLPILP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H186</accession>
    <name>A0A2S9H186_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Heavy metal efflux pump, CzcA family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_1711</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93710">
        <property type="protein sequence ID" value="PRC93710"/>
        <property type="gene ID" value="S2091_1711"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2090.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027463">
        <property type="entry name" value="AcrB_DN_DC_subdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001036">
        <property type="entry name" value="Acrflvin-R"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004763">
        <property type="entry name" value="CzcA/CusA/SilA/NccA/HelA/CnrA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32063">
        <property type="entry name" value="PTHR32063"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00873">
        <property type="entry name" value="ACR_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00702">
        <property type="entry name" value="ACRIFLAVINRP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82714">
        <property type="entry name" value="SSF82714"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00914">
        <property type="entry name" value="2A0601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="14"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="334"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="360"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="386"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="436"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="465"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="522"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="859"/>
            <end position="878"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="885"/>
            <end position="905"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="911"/>
            <end position="935"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="956"/>
            <end position="976"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="988"/>
            <end position="1013"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC93710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="1031" mass="112923" checksum="33E49922A605EAF5" modified="2018-07-18" version="1">MINQLISICFRRRYLAWVLAILIVIYGYVSWTNMAVEAYPDISDVTVQVTTQVPGLAAEEIEQQITAPLERALSNTPGLVTMRSSSTFALSLITLVFKDGSEDYFVRQRVLERIATVTLPTGVQPSLDPISGAAGEIYRYTLESDSKNLMELSEIQKWIVIPALKQVPGIADVANFGGFTKEFQLELNPTQLQRYNLALADVVTAINNNSANAGGGRISRGEQSYVIRGIGQIHSLDDLGAVVVTQNNGSPVLLRDLGKLQFGHQEREGILGKDNNPDTLEGIVLMLKYENPSMILQGVHSKLAELKKKLDPMDVKIVPYIDRDDLVKLTVHKVSHTVLEGIGLVCIVLILFLGSPRSAIVAAVAIPIALVTVFIIMHATKMPANLFSLGAIDFGIIVDGAIVVMEAILRRREENPHVELTENDILETSSQVARPIFFATLIIIVAYLPLFAFERAEGKLFTPMAYTVSYALLGALLCTLMLIPGLAYTALRMPRKIFHNKPLAWLTARYRATLGHLLERPWIAYILASIALVSVLILGATAGREFLPELDEGALWLQVQMPTGLSLEKASEMASELRREIKSFPEVSYVISQLGRNDDATDPWTPSHIEMPVGLKPYDQWPSGESKAELINRMNERFKNMPGFSIGISQPIIDGVNDAIGGAHSPLVLRVYGSDLKEDRRIASQIVDILGSIRGTASASLFQEPPIPQMAIKINREAAARFGINVNDIANLIQTGVGGAPVTTIYQSERIYNLTVRFPKANKNSPEALGNLHLNSSTGAKIPLSQLASITLQTGESTISHETSERQITIRIDNRGRDLTSYLAEAQQRIDKEVKFDAQHNRLEWAGQFENQRRAQARLVVILGVMLLMMAVLLYFQFGKLRQSFLILGVVPLATLGGLIALHVTGETLNVATAVGFIALFGVSVQNGIIMVANFRRVHGEGLSLSQTVIEGATERLRPVLMTATVASIGMLPAALATGVGTDVQRGLATVVVGGLVVSTLLTLFILPTFYFAMETYVAGKSWGIRRRQDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1K8</accession>
    <name>A0A2S9H1K8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1471</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93862">
        <property type="protein sequence ID" value="PRC93862"/>
        <property type="gene ID" value="S2091_1471"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="170"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="267"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="291"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="390"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="171"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="186"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="267"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="302"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="403"/>
            <end position="428"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="428" mass="46479" checksum="A5A2F9765BE88522" modified="2018-07-18" version="1">MVEIRSGNALSGACAIPEQDVLNLQDRLTQKSKHDHHDSEQVESVDPFLWPFQEILPPLGLQENVGVAPARPEVGASPGRYATDTRPEAREALLDWSLHSQPQALNVLTKGAFVLSDSKASPSPGQLKQIVSQTGGVTAEVATAIVGGVLDHLSDQPMKKLPTYLRAEEFPRTADTGHKGTVADDGELQSRSSPIVVQQQSRQGSALTTPATARQESPTEALPDSKTPPSSGNLTQVVSYTGGVTAEVVADIVGRVLDDLTDRTLTKSSEYPRAEETPRTAEARRKAATVFSADDGQLQGRPSPIEVQQKGRQSSVLTTPATVRQESPTVHPGRMGTSDRVVQNSWVYKFRSWGKEHAVTILSTLGSSPQLLSSLTLQPTSALVEQRLNAHGDMPGSSDQWVFQDHGDERRQQQDARHQYREQEEDES</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1P9</accession>
    <name>A0A2S9H1P9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1523</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93914">
        <property type="protein sequence ID" value="PRC93914"/>
        <property type="gene ID" value="S2091_1523"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="16"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="155" mass="18216" checksum="65BCBFA3F547B8EE" modified="2018-07-18" version="1">MQREPRGFQYGLEPLRRKSDWELQELRQTLARLNTEIAAQTQTVQQYEDRLSVATKDIARQQGKSQIIHIDKQFIAHTYIAHQMQLLALARKALTQLETNRDQTIQNLHRLQKFADGLEEHREEEVKDYTQVLEKVSIAEADDAWLRGIHWKAAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1T3</accession>
    <name>A0A2S9H1T3_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Flagellar basal body protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_1512</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 4">Bacterial flagellum basal body</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the flagella basal body rod proteins family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93903">
        <property type="protein sequence ID" value="PRC93903"/>
        <property type="gene ID" value="S2091_1512"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009425">
        <property type="term" value="C:bacterial-type flagellum basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001444">
        <property type="entry name" value="Flag_bb_rod_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020013">
        <property type="entry name" value="Flagellar_FlgE/F/G"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010930">
        <property type="entry name" value="Flg_bb/hook_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037925">
        <property type="entry name" value="FlgE/F/G-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00460">
        <property type="entry name" value="Flg_bb_rod"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06429">
        <property type="entry name" value="Flg_bbr_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117143">
        <property type="entry name" value="SSF117143"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03506">
        <property type="entry name" value="FlgEFG_subfam"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0975">Bacterial flagellum</keyword>
    <keyword evidence="7" id="KW-0966">Cell projection</keyword>
    <keyword evidence="7" id="KW-0969">Cilium</keyword>
    <keyword evidence="7" id="KW-0282">Flagellum</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flg_bb_rod" evidence="5">
        <location>
            <begin position="5"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="domain" description="Flg_bbr_C" evidence="6">
        <location>
            <begin position="211"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU362116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF06429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC93903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="290" mass="30288" checksum="F2F71229516240C4" modified="2018-07-18" version="1">MNNSLYIAATGMQAQQLNLDTIANNLTNLSTNGFKSSVVNFQELMYVDPVGARSAQTEMHSVHSGMHGVHGDHSAHGIQSTQGQDSDAATSAITPYGTGVSVGSVTKDFSLGTMTQTNSQMDLAIQGNGFLEVTMPDGSHAYTRGGTLSVGADNFLMSPQGYELKPSIRLPANPTSITIAQNGQVSVTTGTSAQPTQVGQIELANFNNPGALNPQGNGIYVPTAASGNPTYSVPGSTNAGTLAQGSLEGSNVNMVNQMVNLMVAQRAYELSSKVVQTADELMSLTNNLRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1Y7</accession>
    <name>A0A2S9H1Y7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Glycosyl transferases group 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1136</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC93963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93963">
        <property type="protein sequence ID" value="PRC93963"/>
        <property type="gene ID" value="S2091_1136"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="528" mass="59936" checksum="83A7C6E8CA31BE1D" modified="2018-07-18" version="1">MNFILFSDISETTINKGLGLPEYSYYFVLKSFHTALSELGTVTIVQHPETEVDALFEVCQQRDEECLFLSFSPPNKTLVDLKCPTISVFAWEYSNIPTEQWDEDLRNDWRTVFACHGRTIALSGYTVRAVQDAMGVDFPVLGVPTPLWNQFSGARERLGPVIVGAKTTISLRGTVLDSRQLNLSPDFLISRIPAPVVTVEQQVEIALPLPTDTELLQSAAVPAKTLGYRLEVTKRLLLDWYREVIRDLMPLWFAKLLAVSGRKIIALVRHEVKREVPPPEVPEPIQEEVPELIQEEVPEPIIQPEPPEVEMSLGGVVYTSVFSPKDGRKNWFDMVTAFCWTFRDVEDATLVLKMNAGDLSSYQPTLITLLSQLSPFKCRVVTVHGFLDDATYEQLIGATTYYVNTSLCEGLCLPLLEFMSCGKPVIAPGHTAMEDYIDESVAFMIKSGLEHNVWPHDPRDLFRTLRYRLDWSSICTAYWDSYQMARNAPQEYQKMSNRVLERLQSYASVAVVKEKLQNFFQQTNSRNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H206</accession>
    <name>A0A2S9H206_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transposase IS200 like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1194</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94021">
        <property type="protein sequence ID" value="PRC94021"/>
        <property type="gene ID" value="S2091_1194"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002686">
        <property type="entry name" value="Transposase_17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036515">
        <property type="entry name" value="Transposase_17_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01797">
        <property type="entry name" value="Y1_Tnp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01321">
        <property type="entry name" value="Y1_Tnp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143422">
        <property type="entry name" value="SSF143422"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Y1_Tnp" evidence="2">
        <location>
            <begin position="9"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="211"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="241" mass="27984" checksum="C426EA2816D9F4DF" modified="2018-07-18" version="1">MARLPRLTIANHQHHIIQRGNDNRLIFCDADDVALFRQLLLEAAKKFDVAIHAYVFMPNHFHLLATPQTDDGLGRMMQWLGRHYVPYFNRRYERSGTLWQGRFKSLLIDSAAYFMLCSRYIESNPVRAGLVSAPADYVDSSYLHHIGALVDPLISDHPLYWNLGNTPFQREAVYKELLEQALTLKEIEEITKACLKGWPLGSSHFKEQLEKQASRRINPLKRGRPRLHKPKLEKQDENNPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H220</accession>
    <name>A0A2S9H220_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Putative membrane protein insertion efficiency factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1205</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Could be involved in insertion of integral membrane proteins into the membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0161 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94032">
        <property type="protein sequence ID" value="PRC94032"/>
        <property type="gene ID" value="S2091_1205"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00386">
        <property type="entry name" value="UPF0161_YidD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002696">
        <property type="entry name" value="Membr_insert_effic_factor"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33383">
        <property type="entry name" value="PTHR33383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01809">
        <property type="entry name" value="YidD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01234">
        <property type="entry name" value="Haemolytic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00278">
        <property type="entry name" value="TIGR00278"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="108" mass="12246" checksum="66BB48D6D3E93835" modified="2018-07-18" version="1">MKSILLFLLRAYKLTISPYLGQNCRFYPSCSAYAELAIRRHGVLKGSALAGKRLCKCHPWHSGGIDLVPENETNKDQQPDENSKTRLKLARSYCGTHNKCTSHHHLHN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H285</accession>
    <name>A0A2S9H285_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Efflux transporter, RND family, MFP subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1274</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94101">
        <property type="protein sequence ID" value="PRC94101"/>
        <property type="gene ID" value="S2091_1274"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039562">
        <property type="entry name" value="MFP_biotin_lipoyl_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006143">
        <property type="entry name" value="RND_pump_MFP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13533">
        <property type="entry name" value="Biotin_lipoyl_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01730">
        <property type="entry name" value="RND_mfp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Biotin_lipoyl_2" evidence="2">
        <location>
            <begin position="75"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="390" mass="41578" checksum="508F9A3753F77A30" modified="2018-07-18" version="1">MKSMQVFQTLTKGPRAILLGLGLLVVLFAVMMGSATKSAPIVNAKPVILVESVLASKRDLPIYITGLGAVQAFYTVTISPRIDGELMKLGFTEGQMVKPGDLLAQIDPRPYQAALDQAVAGKAKDVAQLANAKIDLERYQSLAPEEFTSKQTLETQRALVAQTVAQIAVDDAAIDSAKTQLSYATIRSPIAGRTGIRLADPGNILHSATASGIVVVTQVQPISVIFTLPAESLQVVHSAMSAATVSVSAVSRDGSTLLGVGTLGLIDNQIDPTTGTMKLKATFPNQDNRLWPGDFVNARVLVETRHDAITIPSSAIQRGPDGVFAYVVKKDNTVEMRSLKLGAETDGVVIVEQGLQEGERVTTNNQYRLQPKVHVQFTDAVNRVIGTKAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H286</accession>
    <name>A0A2S9H286_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF4166 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1240</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94067">
        <property type="protein sequence ID" value="PRC94067"/>
        <property type="gene ID" value="S2091_1240"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025311">
        <property type="entry name" value="DUF4166"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13761">
        <property type="entry name" value="DUF4166"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4166" evidence="1">
        <location>
            <begin position="42"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="204" mass="23462" checksum="CD8FD24D38BE13D7" modified="2018-07-18" version="1">MKKIILGRYLPLFAKRVIYTDQRESSAQSVFRNALGSTWSDLPEQIRQMHDAPSGTKFNGIAEIKRGNSWLVKFILIIFRFPNEGNDVPVEVCITKSSDAESWQRNFNGKIFRSEISNGQGKYEHLICERFGPFTFGIALVPENGKLNYEVRRWRFLQIPLPGFLCPGGDSFEYVSNDKFYFNVEIKYALSGLIVSYRGWLIAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2F2</accession>
    <name>A0A2S9H2F2_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 8 11">50S ribosomal protein L22</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">rplV</name>
        <name evidence="12" type="ORF">S2091_1310</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.</text>
    </comment>
    <comment type="function">
        <text evidence="7">This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.</text>
    </comment>
    <comment type="function">
        <text evidence="8 11">This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8 10">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 8 9">Belongs to the universal ribosomal protein uL22 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94137">
        <property type="protein sequence ID" value="PRC94137"/>
        <property type="gene ID" value="S2091_1310"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00336">
        <property type="entry name" value="Ribosomal_L22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01331_B">
        <property type="entry name" value="Ribosomal_L22_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001063">
        <property type="entry name" value="Ribosomal_L22"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018260">
        <property type="entry name" value="Ribosomal_L22/L17_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036394">
        <property type="entry name" value="Ribosomal_L22/L17_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005727">
        <property type="entry name" value="Ribosomal_L22_bac/chlpt-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13501">
        <property type="entry name" value="PTHR13501"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00237">
        <property type="entry name" value="Ribosomal_L22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54843">
        <property type="entry name" value="SSF54843"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01044">
        <property type="entry name" value="rplV_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00464">
        <property type="entry name" value="RIBOSOMAL_L22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8 9" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 8 9" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4 8 10" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 8 10" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PRC94137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="109" mass="11971" checksum="26AD4D5C3442598B" modified="2018-07-18" version="1">METKAILRGVRLSDQKGRLVADQIRGKKVDQALNILAFSPKKGAAIIKRVLESAIANAEHNDGADIDELRVKTIYVEKGAVLKRFTARAKGRGDRISKQSCHIYVTVGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2G8</accession>
    <name>A0A2S9H2G8_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6 7">50S ribosomal protein L10</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rplJ</name>
        <name evidence="8" type="ORF">S2091_1331</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 6">Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the universal ribosomal protein uL10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94158">
        <property type="protein sequence ID" value="PRC94158"/>
        <property type="gene ID" value="S2091_1331"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070180">
        <property type="term" value="F:large ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd05797">
        <property type="entry name" value="Ribosomal_L10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1730">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00362">
        <property type="entry name" value="Ribosomal_L10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022973">
        <property type="entry name" value="Ribosomal_L10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043141">
        <property type="entry name" value="Ribosomal_L10-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002363">
        <property type="entry name" value="Ribosomal_L10_eubac_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001790">
        <property type="entry name" value="Ribosomal_L10P"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11560">
        <property type="entry name" value="PTHR11560"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00466">
        <property type="entry name" value="Ribosomal_L10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160369">
        <property type="entry name" value="SSF160369"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01109">
        <property type="entry name" value="RIBOSOMAL_L10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 6 8" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002633"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC94158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="183" mass="18887" checksum="E858853839D382E3" modified="2018-07-18" version="1">MSLNLNDKKAVVAEVSAKVATAQTIVVAEYRGIQVGHLTQLRAKARAQGVYLRVLKNTLARRAVEGTAFASLGNEMTGPLIYAISDDAVAAAKVTFEFSKTNDKLVIKAGNYAGKSLDKAGVAALASIPSREVLLAQLLGVMLAPVSGFARGLAALSAKKVSELPPAPVAEVAEVAATEAAAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2V3</accession>
    <name>A0A2S9H2V3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SnoaL-like domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0933</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94312">
        <property type="protein sequence ID" value="PRC94312"/>
        <property type="gene ID" value="S2091_0933"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037401">
        <property type="entry name" value="SnoaL-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12680">
        <property type="entry name" value="SnoaL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SnoaL-like" evidence="1">
        <location>
            <begin position="20"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="132" mass="14397" checksum="578162E9A7F46C76" modified="2018-07-18" version="1">MSTSQTSQLIAEQAHRIATQYIAVWDEMGATHRRSLISSTFTPDVEYTDPMMQSASHDGMDKMIAAVQAQFPDFRFQLHGTPDGHNNVVRFSWKLAAKNAAPVAFGTDIVIVTEDGRISKVTGFLDAAAVPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H357</accession>
    <name>A0A2S9H357_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1029</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94408">
        <property type="protein sequence ID" value="PRC94408"/>
        <property type="gene ID" value="S2091_1029"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="58" mass="6798" checksum="29AA03ED95378B02" modified="2018-07-18" version="1">MIWGSIDKSHRKTNAQSLLDCVEHAEIIEFEDCGHFPDIEQPERYVNHLTQHITKHAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3E6</accession>
    <name>A0A2S9H3E6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_0505</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94502">
        <property type="protein sequence ID" value="PRC94502"/>
        <property type="gene ID" value="S2091_0505"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006744">
        <property type="term" value="P:ubiquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07377">
        <property type="entry name" value="WHTH_GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1410.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028978">
        <property type="entry name" value="Chorismate_lyase_/UTRA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011663">
        <property type="entry name" value="UTRA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00392">
        <property type="entry name" value="GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07702">
        <property type="entry name" value="UTRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00035">
        <property type="entry name" value="HTHGNTR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00866">
        <property type="entry name" value="UTRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64288">
        <property type="entry name" value="SSF64288"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50949">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0831">Ubiquinone biosynthesis</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="3">
        <location>
            <begin position="16"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC94502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="244" mass="26890" checksum="50221AACD13D57DE" modified="2018-07-18" version="1">MLSPLNDFKPDSESATPLYLQLSNKLATAIHSGIWQPDEALPSERTLSEQLGISRVTARKAIDMLCERGMLTRRQGSGTFITPKLEQPLSRLTNFSEELRQRGFVPGSQWISRETGVAAPEEILSLGLSPNTVVSRLKRLRTADNVVMAIESSTIPAQYLPNPKAVTDSLYGYLDTHGAAPTRALQHIRAVNATPEQAKLAGIKQGAAMLFITRVGYHSNGAAIELTHSYCRSDYYDFVAELFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3G2</accession>
    <name>A0A2S9H3G2_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ammonium transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">S2091_0525</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the ammonia transporter channel (TC 1.A.11.2) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94522">
        <property type="protein sequence ID" value="PRC94522"/>
        <property type="gene ID" value="S2091_0525"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008519">
        <property type="term" value="F:ammonium transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3430.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029020">
        <property type="entry name" value="Ammonium/urea_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001905">
        <property type="entry name" value="Ammonium_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018047">
        <property type="entry name" value="Ammonium_transpt_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024041">
        <property type="entry name" value="NH4_transpt_AmtB-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43029">
        <property type="entry name" value="PTHR43029"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00909">
        <property type="entry name" value="Ammonium_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00836">
        <property type="entry name" value="amt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01219">
        <property type="entry name" value="AMMONIUM_TRANSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0924">Ammonia transport</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015565762" description="Ammonium transporter" evidence="9">
        <location>
            <begin position="25"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="75"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="108"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="177"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="206"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="259"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="292"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="324"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="357"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="384"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="412"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="455"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="domain" description="Ammonium_transp" evidence="10">
        <location>
            <begin position="75"/>
            <end position="511"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC94522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="513" mass="53029" checksum="DB6A35A408152BAA" modified="2018-07-18" version="1">MKNLFTHTVVGLVAALCFVGNAAAQEKVTPATAASVSASATAPAATPTALTTVAATPAVATVAAAAPTPNKGDTAWMMVATLLVILMTIPGLALFYGGLVRSKNMLSILIQVFMIFAVIIVLWCIYGYSLAFTEGGSFIGSLTGPDSRMFLNGIFDPAKGTFATVATFSKGVVIPEFVYVAFQGTFAAITCGLIIGAFAERAKFAAVLLFVVLWFTFSYLPIAHMVWFWPGPDGIKDAASLAFETAKGGWLWQKGALDFAGGTVVHINAAVAGIVGAYMIGRRVGYGKESMAPHSLTMTMIGASLLWVGWFGFNAGSALEAGDIAALAFINTLLATAAASVAWVFGEWLVKGKPSMLGGASGAVAGLVAITPACGFVGPMGALIMGLLAGLICLWGVNGLKRLLGADDSLDVFGVHGVGGILGALLTGVFASPALGGQGIFDYVTNKMSADPYSIVSQVIIQGEAVLTTVLWSGLVSVIAYKLVDLMIGLRVPEDEEREGLDITSHGESAYHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3Q7</accession>
    <name>A0A2S9H3Q7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0612</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94609">
        <property type="protein sequence ID" value="PRC94609"/>
        <property type="gene ID" value="S2091_0612"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="153" mass="16997" checksum="9DF2AEB8216BD454" modified="2018-07-18" version="1">MQSLTLEQLRATHEAGGITGVTIKAQGGDFLVRFVTRNGDAVLTKARSTEPRYFSNPLQAINLLKGVGIMIGTFDVSLWNPLQKNTSRVRPDRAVALKQVHEAADYDRWFRAQVEQGLQEAEDPATEWVTHELVKEDIAQQRAALLVRASGNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3T5</accession>
    <name>A0A2S9H3T5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">PEP phosphonomutase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0633</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94630">
        <property type="protein sequence ID" value="PRC94630"/>
        <property type="gene ID" value="S2091_0633"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00377">
        <property type="entry name" value="ICL_PEPM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039556">
        <property type="entry name" value="ICL/PEPM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_Kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="SSF51621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="267" mass="28328" checksum="C9EA1D7317FF374A" modified="2018-07-18" version="1">MNKNSFNVFQSLHSEPTPLLLPTAWDAASAALFQCDGAKAVATSSAALAWSLGYADGGSLPRQELLAAIRRIVRVLQVPLTVDLEDGYSDSPVTVAELIWEVAQCGVAGINLEDGANSANLLTSKIAAARHSLGTANLFINARTDVFLRNLADGDAAIGMTIERLHHYKDAGADGAFVPGMSRIVDVHQVAPEIGLPLNLMTVPGMPTIDALFAAGVRRVSAGPALFQSSYGQARLLAKKLLVNHDVSGLFDHSLSYDFMNSVFQAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3V7</accession>
    <name>A0A2S9H3V7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Type II secretion system (T2SS), protein F</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_0616</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GSP F family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94613">
        <property type="protein sequence ID" value="PRC94613"/>
        <property type="gene ID" value="S2091_0616"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.81.30">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003004">
        <property type="entry name" value="GspF/PilC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018076">
        <property type="entry name" value="T2SS_GspF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042094">
        <property type="entry name" value="T2SS_GspF_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30012">
        <property type="entry name" value="PTHR30012"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00482">
        <property type="entry name" value="T2SSF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="111"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="136"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="domain" description="T2SSF" evidence="8">
        <location>
            <begin position="16"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="domain" description="T2SSF" evidence="8">
        <location>
            <begin position="200"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC94613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="323" mass="35383" checksum="E44C669A432D5B43" modified="2018-07-18" version="1">MSLPPLADQVRADLFTHLAAMEKAGLPPDKSFSLLRLPGNLQARVVALRKLLGRGVDIPTAGSQSGLFSELETNLLHAAFNAGSPELTYKRMATRYAHKARQASLIKSRMAMPLVVLFIALAVQPLPALVAGTLTASGYLLSIMRPFVLLAGGVFVYKFIATRLFNMTAKPTPIQVGLSTLLTRIPLFGPMLVRRNVRDFYENLALMLEAGLPMLDALPKAVNTVSLCVIRADFSRLQSMMAQGMTLAQAVGNLHYQGKYPVQSFAQTGEGSGSLPEMLLRFADGESEAVAQFQVQVAEWLPRLLYGMVMLWMAYQLLHQHII</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H402</accession>
    <name>A0A2S9H402_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Tautomerase</fullName>
            <ecNumber evidence="3">5.3.2.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_0712</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the 4-oxalocrotonate tautomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.2.-" evidence="3"/>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94709">
        <property type="protein sequence ID" value="PRC94709"/>
        <property type="gene ID" value="S2091_0712"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006725">
        <property type="term" value="P:cellular aromatic compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.429.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004370">
        <property type="entry name" value="4-oxalocrotonate_tautomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014347">
        <property type="entry name" value="Tautomerase/MIF_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018191">
        <property type="entry name" value="Tautomerase_Pseudo-typ"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01361">
        <property type="entry name" value="Tautomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55331">
        <property type="entry name" value="SSF55331"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00013">
        <property type="entry name" value="taut"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tautomerase" evidence="4">
        <location>
            <begin position="2"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; via imino nitrogen" evidence="2">
        <location>
            <position position="2"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR618191-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU362032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC94709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="70" mass="8019" checksum="8B0E4C36AFF224A1" modified="2018-07-18" version="1">MPYINIRVTREGVTPEQKLQLIEGATNLLSRILNKHPSTTFVIIDEVDTDNWGLAGENITSLRRREAKER</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H462</accession>
    <name>A0A2S9H462_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Iron-sulfur cluster assembly protein CyaY</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">cyaY</name>
        <name evidence="4" type="ORF">S2091_0778</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the frataxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94775">
        <property type="protein sequence ID" value="PRC94775"/>
        <property type="gene ID" value="S2091_0778"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008199">
        <property type="term" value="F:ferric iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.920.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00142">
        <property type="entry name" value="CyaY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002908">
        <property type="entry name" value="Frataxin/CyaY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036524">
        <property type="entry name" value="Frataxin/CyaY_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020895">
        <property type="entry name" value="Frataxin_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01491">
        <property type="entry name" value="Frataxin_Cyay"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01219">
        <property type="entry name" value="Frataxin_Cyay"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55387">
        <property type="entry name" value="SSF55387"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03421">
        <property type="entry name" value="FeS_CyaY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01344">
        <property type="entry name" value="FRATAXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50810">
        <property type="entry name" value="FRATAXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC94775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="109" mass="11847" checksum="7D1823D962614E56" modified="2018-07-18" version="1">MTETEFLSLIDATLSQIEDVFEGAGQRGDIDVECSRNGSLLDIEFLHNKSKIIINSQAALSELWVAAKSGGFHYKHDGRQWLNTRDGSELMAVLAGIALEQGGLVIDLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H485</accession>
    <name>A0A2S9H485_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">2-enoyl-CoA Hydratase C-terminal region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0792</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94789">
        <property type="protein sequence ID" value="PRC94789"/>
        <property type="gene ID" value="S2091_0792"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003860">
        <property type="term" value="F:3-hydroxyisobutyryl-CoA hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045004">
        <property type="entry name" value="ECH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032259">
        <property type="entry name" value="HIBYL-CoA-H"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43176">
        <property type="entry name" value="PTHR43176"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16113">
        <property type="entry name" value="ECH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ECH_2" evidence="2">
        <location>
            <begin position="16"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="364" mass="40588" checksum="D16C9F5F45666EF4" modified="2018-07-18" version="1">MTDFADFILTRVQNQIGFITLNRPKALNSLSLEMIRSITQTLLDWQERSDVRAVFIHGSHERAFCAGGDIRFFYDVGTATPLGDSALLEDFFTEEYALNYLIHHYPKPYVSLLNGVVMGGGMGIAQAGPDNRLRIVTERTKMAMPEVNIGLFPDVGGGYFLSRCAGQIGTYLGLSGEIINASDAIYADLADVYLPSEQIPALMTLLEQSNTSDLRDSIRQFAAPFQQQLNAGPLATNRNALDQHFSHNNVAAIMASLQADPSPFAQQTFKLMQTRSPLLMCVTLEQLQRGQKLSVAECLRMERTMVRHCFKHGEVLEGVRALVVDKDMQPKWQPASLEEVSPELINSFFAEVWPAYAHPLRELN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4A0</accession>
    <name>A0A2S9H4A0_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">YceI domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0709</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94706">
        <property type="protein sequence ID" value="PRC94706"/>
        <property type="gene ID" value="S2091_0709"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007372">
        <property type="entry name" value="Lipid/polyisoprenoid-bd_YceI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036761">
        <property type="entry name" value="TTHA0802/YceI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04264">
        <property type="entry name" value="YceI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00867">
        <property type="entry name" value="YceI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101874">
        <property type="entry name" value="SSF101874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015392795" description="YceI domain-containing protein" evidence="1">
        <location>
            <begin position="22"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="domain" description="YceI" evidence="2">
        <location>
            <begin position="26"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="195" mass="21018" checksum="08AC427B2EA05EE8" modified="2018-07-18" version="1">MKLALLLACAIALSLPTIGHTDEYNTVQSDKSTLTFGFKQMGVSMNGKFKKFDVQMNFDPANLIASKAQFNLDLVSIDIGSDEGNDEVIGKQWFNVKAFPKASFTSNSIKSLGGNRYEVSGPLTIKGHTKIVTTSANMTISGKTASFDGAFVILRTDYNIGEGAWSSVDIVANEIQIKFHLLASVGKSVLAGNQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4S6</accession>
    <name>A0A2S9H4S6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">TPR repeat</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_0180</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94985">
        <property type="protein sequence ID" value="PRC94985"/>
        <property type="gene ID" value="S2091_0180"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008476">
        <property type="term" value="F:protein-tyrosine sulfotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006478">
        <property type="term" value="P:peptidyl-tyrosine sulfation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026634">
        <property type="entry name" value="TPST"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12788">
        <property type="entry name" value="PTHR12788"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="28"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="62"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="96"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="130"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="164"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="198"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC94985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="594" mass="66979" checksum="3185D674C0D64482" modified="2018-07-18" version="1">MLIGLVVFSGRRWVMKIAGRFAPDHSAALALKDQGNAHLCNGQLEIAAESYRQAIVQNPSYAEAYSNLGFVFGLQSSLDEAIVHYRKAIELKPDLYPAHQNLGVALLKLGQTDAAEKSFRRVIALAPEHSIAFNNLGEIAVQRGDFSNAETLLLRALELQPEYAEAYSTLGIALHMLGRQSEAEAHYRRALELKPDFDTAYCNLGIVLMELGKMGEAEKSLSTALELTPSSIPSLLALLTLVPYQPDDPRFNQLETIYSNRELLSLDDQIKLNFAMGKAMESIAQFDRSFSAYEEGNQLSYQRDYFDDSAEDRALEKLSGIFTSDLFSKCAALEETLPIPEKDRVPIFIVGMPRSGSTLIEQILSSHREVYGAGEIVTFAEFAKKAYSLLDSLDSEAALLALRKLGQEYLDRVWKLAPNACFITDKMLENYQHLGLIYLMIPSAKIIHSMRNPMDTCFSCYAQPFSIGNTYSFDLQTLGRQYFRYSKLMSHWHNVLPSGWILDVSYEANVANLEGQTRRMLDYLGLTWEATCLRFYENKRIVRTASTPQVRKPIYSNSIGRWKHFAKHLTPLFEIIHPTMPVTIEDEIQDQINA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4T8</accession>
    <name>A0A2S9H4T8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="10">FtsX-like permease family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">S2091_0148</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94953">
        <property type="protein sequence ID" value="PRC94953"/>
        <property type="gene ID" value="S2091_0148"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025857">
        <property type="entry name" value="MacB_PCD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12704">
        <property type="entry name" value="MacB_PCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="298"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="343"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="388"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="432"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="686"/>
            <end position="710"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="730"/>
            <end position="757"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="769"/>
            <end position="791"/>
        </location>
    </feature>
    <feature type="domain" description="MacB_PCD" evidence="9">
        <location>
            <begin position="20"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="8">
        <location>
            <begin position="325"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="8">
        <location>
            <begin position="715"/>
            <end position="798"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF12704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC94953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="808" mass="88583" checksum="36F5D4DA27E2C1A5" modified="2018-07-18" version="1">MNLRDFRIGWRLLIQEPAYSAVVLLGLSIGFATCFLLFSFVRYSWQYNSKIPDVGNVYVVKERYNIDPVAPWSDLAPFLLREAAMKMPGIVDASGFQIGRDLTIRTGDQLHKLYGIPVLPGFAQLLGLQVIEGDIKSALEQPDSFVITQAAAEQTFGTSHALGRTIQTSGKVLRVSAIVRDQPANTTIPFDALIGTSSVLFSDELRNNMLRGGSMGKLLIRVQPGASLSAITENLQKIVDDAPQVWHGSPEMKARLGKRKVMDIKLSPLRDAYFDREVANNPITVPGDRGDPAIVTGLAAIAVLILALAAINYVNLATVRVLQRQREIGMRKAIGATAQQIILQFLCESLVVALLATGLGLLLAWLLLPVFSDLMHRKLEDVFSAANVVAALMIGALVGTLTAVYPTWIAIRVHPLQVLVGRSDTESMRGRQLRRILTVLQITVALSLASVTLAIEWQTNFAIHASPGFVPDQLLIVDLPERMKDSEKPHAFTAALSQQKGIAGIAISTDAVGRSNERWGMDVRREGKASVFLEMKSVSANYFEQYGIKPVAGRLFDARIDKEDDPEPIILNTVATHALGFTSPEAALGQILFYTDFHEKKLTKRIVGIAPELRYLSLHEPPRATAWELYLNGSTLSVRFTGSLNEAEQTVQTLWPTYFPDAIMEMQPAKAILAANYADETRIAKLLAISTGIAMAIAAFGIYALSAYTVQRRTKEIVLRKLYGARQRDIAQLVVKEIGLLTFLAALIGLPFAAVAIERYLAGYVEHAAIGYWTLLFALITAVAIALIATARHAWVAIRMTPALILRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H522</accession>
    <name>A0A2S9H522_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Methyl-accepting chemotaxis protein (MCP) signaling domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">S2091_0263</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the methyl-accepting chemotaxis (MCP) protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95068">
        <property type="protein sequence ID" value="PRC95068"/>
        <property type="gene ID" value="S2091_0263"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004089">
        <property type="entry name" value="MCPsignal_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029095">
        <property type="entry name" value="NarX-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00015">
        <property type="entry name" value="MCPsignal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13675">
        <property type="entry name" value="PilJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00283">
        <property type="entry name" value="MA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50111">
        <property type="entry name" value="CHEMOTAXIS_TRANSDUC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0807">Transducer</keyword>
    <keyword evidence="2 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="99"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="391"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="11">
        <location>
            <begin position="451"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="domain" description="Methyl-accepting transducer" evidence="10">
        <location>
            <begin position="504"/>
            <end position="740"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="412"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="575"/>
            <end position="602"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00029447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PRC95068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="778" mass="83586" checksum="B5769B93C499FA1D" modified="2018-07-18" version="1">MALHLPLPSAAEVPSEHDEDKDKLSENLNPATLIDLEATQTEFGLSSIKPKKAGKAAKAGKKEEEQDNNLTFIGDVLESGRDIKLPLIGHLSLQRQVRFLFVVMLVALVFGGLFVWLNSSQKSIASIQTQIAGDALMHSQRIGKAAPNAIQGNPEAFKQLEESRSELNADLNVLTKGGTYKGYSLDSAKSADLAVLKDSAKIWSNTDKAAETILKLKKELTGFGQTLEKLNTISPTLLELTEEISAQKVQAGGSAREISASGQLVMLTQRLARSASEFLTAEGVNPETAFLLGKDTNTFRDLVDGFLSGSDVLKLTATKDEETRSKLTELKTTFVDYQQSVSTLLGNFQNFASAKQAEQSVFTDNEELRMHLISVQKNYRDHLDSTNFSSYLMFLAFALALLAAAGIASVLLQDSRNRAKEANARRVEADIQMMQAQKQENEAKQANDQNQAAILRLMNELQEVADGDLTVQATVSEDITGAIADSVNYTVEELRGLVGRVTSTAEQVTSASNQAEGVSVALLSASQQQSREIKDAGEAMLTMAGDITDVSKSASESADVARLSVVAAEQGAQAVQNAIKGMDEIREQIQETSKRIKRLGESSQEIGEITELISDITEQTNVLALNAAIQAASAGEAGRGFSVVAEEVQRLAERSGEATKQIGALVKTIQTDTHDAVSAMEKSTQGVVEGAKLSDAAGTALAEIRRISNQLADLIQGISNSTEQQATSANGVAQNIQHILTITEQTQSGTQQTAQSIRELSGLAQELKNSVSRFRVAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H599</accession>
    <name>A0A2S9H599_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GDSL-like Lipase/Acylhydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0241</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95046">
        <property type="protein sequence ID" value="PRC95046"/>
        <property type="gene ID" value="S2091_0241"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001087">
        <property type="entry name" value="GDSL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00657">
        <property type="entry name" value="Lipase_GDSL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015723263" evidence="1">
        <location>
            <begin position="28"/>
            <end position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC95046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="372" mass="37712" checksum="DA998A27167690E8" modified="2018-07-18" version="1">MRQNKFSLVVAAAIAVLVAGCGGGGSAGNQAPKVQFSSQVSFGDSLSDVGTYAVGLIGSSGGGRYTVNAALANGMPAPTNWTELMAATLHQSAPCPAETGLNGAAAYDLSIPVVMHTPGCTGYAQGGAMVTYPYGPGNANVGPFPNGNPVDGSALLGQLTVPVVTQIQNHLTAHGGSFSGNEVVFLLAGGNDAIVNTEYYLGGGQTAAAAVQAMTLAGTQLAGYINTMILANGAKYVVVLNIPDLSTTPFGNESEAAFPGARAVIKSMVTAFNSQLQAGLTSSNVLIVDVNTVSTSQVMNPSAYGLTDVTDTACNLAPAVNPLSSSLVCSAKNVIAGDISHYEFADQVHPTPYGNILIARYVSSQMAIKGWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5B2</accession>
    <name>A0A2S9H5B2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0352</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95157">
        <property type="protein sequence ID" value="PRC95157"/>
        <property type="gene ID" value="S2091_0352"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="16"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="91"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="115"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC95157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="147" mass="16425" checksum="1064D73329C652E4" modified="2018-07-18" version="1">MLAAATRLSSFKISKLARYSVAVVILLAGIAVWWNALLPLKLYPVLVNAVLLATFSYSLVFPPSMVEFFARMSEPDLPLVAVAYTRRVTQIWCVFFIVNGAIALVTAIWASEAIWSLYTGVISYGLMGVLFGGEFLYRLRFKRLNHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5E1</accession>
    <name>A0A2S9H5E1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putative acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_0348</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95153">
        <property type="protein sequence ID" value="PRC95153"/>
        <property type="gene ID" value="S2091_0348"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009247">
        <property type="term" value="P:glycolipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd07984">
        <property type="entry name" value="LPLAT_LABLAT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014548">
        <property type="entry name" value="Ac_Trasf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004960">
        <property type="entry name" value="LipA_acyltrans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30606">
        <property type="entry name" value="PTHR30606"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03279">
        <property type="entry name" value="Lip_A_acyltrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028561">
        <property type="entry name" value="Ac_Trasf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC95153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="327" mass="36984" checksum="E468A3B0F1ADC26E" modified="2018-07-18" version="1">MKPGEDKAPATQTAHWAAINEVSFLAGIRLMFWICKVFGRWPFRLILYPVLLWYVLVSSSARRASREYLKRVNQIAPIGTSIFKVIQHFAAFAEMMLDKMLLWSGLFDTSSVQYFGVEQMEQLIAEKRGAILICSHLGNLDLCRVLSSKRNNLKLTVLVHTKHAQVFNNMLGSINPNSQLNLMQVSEMTPATAMLLAEKVAQGEFIVIAGDRVPVAENPRVAVTTFLGQPAAFPIGPYVLASILQCPIYMLFSMRRESGTETHSEIHFELLRDAVRLPRKGREQALTELVAAYVARLEAHCLSAPLQWFNFYDYWHLPQLDISDATR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5F4</accession>
    <name>A0A2S9H5F4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative NADH-flavin reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0414</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95219">
        <property type="protein sequence ID" value="PRC95219"/>
        <property type="gene ID" value="S2091_0414"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13460">
        <property type="entry name" value="NAD_binding_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-bd_dom" evidence="1">
        <location>
            <begin position="7"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC95219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="216" mass="23192" checksum="29A8D8593E45CD31" modified="2018-07-18" version="1">MKIILIGASGFIGSALLQEALSRQHQVTALVSNPAKIAAQANLTIVATNVNDTTALTEQLRGADAVISAFSGHAQADVYEYYVKGVQSIIAATKAAKTDKKSPRLLMVGGAGSLEVAPGLQVVDTPSFPEQWKATAEGARQALTLLKQETELNWTMLSPAAHIEPGQRTNQFRLGLDQLLVDAKGESHISLQDYAVAMLNELENPVHTRQRFSIAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5I0</accession>
    <name>A0A2S9H5I0_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Peptide deformylase</fullName>
            <shortName evidence="2">PDF</shortName>
            <ecNumber evidence="2">3.5.1.88</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Polypeptide deformylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">def</name>
        <name evidence="3" type="ORF">S2091_0422</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>H2O + N-terminal N-formyl-L-methionyl-[peptide] = formate + N-terminal L-methionyl-[peptide]</text>
            <dbReference type="Rhea" id="RHEA:24420"/>
            <dbReference type="Rhea" id="RHEA-COMP:10639"/>
            <dbReference type="Rhea" id="RHEA-COMP:10640"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:49298"/>
            <dbReference type="ChEBI" id="CHEBI:64731"/>
            <dbReference type="EC" id="3.5.1.88"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="2">Binds 1 Fe(2+) ion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the polypeptide deformylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.88" evidence="2"/>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95227">
        <property type="protein sequence ID" value="PRC95227"/>
        <property type="gene ID" value="S2091_0422"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042586">
        <property type="term" value="F:peptide deformylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00487">
        <property type="entry name" value="Pep_deformylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.45.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00163">
        <property type="entry name" value="Pep_deformylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023635">
        <property type="entry name" value="Peptide_deformylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036821">
        <property type="entry name" value="Peptide_deformylase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10458">
        <property type="entry name" value="PTHR10458"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01327">
        <property type="entry name" value="Pep_deformylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004749">
        <property type="entry name" value="Pep_def"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01576">
        <property type="entry name" value="PDEFORMYLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56420">
        <property type="entry name" value="SSF56420"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00079">
        <property type="entry name" value="pept_deformyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" evidence="2">
        <location>
            <position position="145"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="102"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="144"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="148"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC95227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="180" mass="20035" checksum="AD65374DEA3EAA44" modified="2018-07-18" version="1">MTIREILKMGDPRLLRTAQLVPPEMLGSTELKQLIEDMFDTMHANDGVGLAAPQIGVDLQLVLFGFEDSDRYPDAPSVPQTVLINPVITPLDAVQEDGWEGCLSVPGMRGVVPRWAHIRYEGVDPDGVSIMREVGEFHARVVQHECDHLFGTLYPMRIKDFSQFGFVEVLFPGQDVESDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5Q8</accession>
    <name>A0A2S9H5Q8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Arylamine N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0411</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the arylamine N-acetyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95216">
        <property type="protein sequence ID" value="PRC95216"/>
        <property type="gene ID" value="S2091_0411"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016407">
        <property type="term" value="F:acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001447">
        <property type="entry name" value="Arylamine_N-AcTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11786">
        <property type="entry name" value="PTHR11786"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00797">
        <property type="entry name" value="Acetyltransf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01543">
        <property type="entry name" value="ANATRNSFRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="SSF54001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC95216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="254" mass="28948" checksum="2A0E63C28D692F75" modified="2018-07-18" version="1">MKKTSFSLEQYFNRIHFQGEARATMATVTEMMRCQLFSVPFENLDVQAGKIISLHPSDIVEKIVHRQRGGYCYEVNGLFAMALDALEIPYYFVAARPISHGGIKPKTHMAIIVLLKGEKWLCDLGFGGYGIRAPLRLNLLDTSVCQDGDLFMLSLQTEHEMVVKIHTANGWDEQYAFELAPQIWADFAAANYYNSTHRDSIFVRKLLVVLCSPNGRKILFGNTFKKLENGQQEKQFLTTENRATILREEFGLIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5Q9</accession>
    <name>A0A2S9H5Q9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0483</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95288">
        <property type="protein sequence ID" value="PRC95288"/>
        <property type="gene ID" value="S2091_0483"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC95288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="111" mass="12233" checksum="29BD4A5A0D55B73D" modified="2018-07-18" version="1">MESKISTQHNQQLAQINQKIIADGETLPSVMLKDGSSVQTGTVATMLHNINLYNAGQRGTVETELELAIPTLFKVGLFDLFVPDEWLSDGNSGRQFVGRKAKEFLANKVNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5V7</accession>
    <name>A0A2S9H5V7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative enzyme involved in biosynthesis of extracellular polysaccharide</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0461</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95266">
        <property type="protein sequence ID" value="PRC95266"/>
        <property type="gene ID" value="S2091_0461"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007138">
        <property type="entry name" value="ABM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03992">
        <property type="entry name" value="ABM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51725">
        <property type="entry name" value="ABM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABM" evidence="1">
        <location>
            <begin position="2"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC95266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="114" mass="13026" checksum="56C183FE9062312E" modified="2018-07-18" version="1">MIAVIFEVLPYADAKQQYLDIASSLSPMLMGMDGFISIERFQSLSNPEKILSLSFWRDEAAVAEWRNREEHRAAQSTGRSAIFEDYRLRIASVARDYGMTERDQAPPDSRVQHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GS83</accession>
    <name>A0A2S9GS83_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4720</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000053">
        <property type="protein sequence ID" value="PRC90573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90573">
        <property type="protein sequence ID" value="PRC90573"/>
        <property type="gene ID" value="S2091_4720"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC90573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="140" mass="16357" checksum="AFBE6209456FD566" modified="2018-07-18" version="1">MKIGLCIIILPRIAQVKRKLPCPSHFRFRWCTTKRFTIPLPHRIAIRIRNQARCIELIGVDVINLLCFTSTTCRHGNIDRRAGGGQAIIIRHLRRNLIRARDRIRYHNTIRWLGYGSHESRAIKERHLRDGATAVRCRCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSB3</accession>
    <name>A0A2S9GSB3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Poly-beta-1,6 N-acetyl-D-glucosamine export porin PgaA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_4692</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000045">
        <property type="protein sequence ID" value="PRC90603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90603">
        <property type="protein sequence ID" value="PRC90603"/>
        <property type="gene ID" value="S2091_4692"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901515">
        <property type="term" value="F:poly-beta-1,6-N-acetyl-D-glucosamine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023870">
        <property type="entry name" value="PGA_export_porin_PgaA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03939">
        <property type="entry name" value="PGA_TPR_OMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015573188" evidence="2">
        <location>
            <begin position="29"/>
            <end position="837"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="175"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC90603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="837" mass="93966" checksum="D32E6EADBBC553D6" modified="2018-07-18" version="1">MLVSISAKFFNTRAIILLSFFLLHASNAAVPQKDVDALILSTKGNLSAEQLAPAIEQLRAWHLDDPQNSHLVYDLAVLLDRAGDYPAASAFAPQIIKNDAQVYALSAIAHATLKSGHFQEAEAAYQLLIAKTPDDINAHVGLVYAWMGQKRIQDALDYAQRILPSREEDYSVEQAPMLVALAELFEQRNDWVLAASSYQKVLQLTPDFRYAKRQLVFALSLAGIPYLANFYAKRDLSIFTKEEQYQLEHADIALTIHFGEAQLSSDSARSRVNTTDIALNENAELIRQPEQLTKSKFDRIVALDDRGYMEEAVLIYQELMAAKIAIPLYVKFAVADAYAYLEQPDKARDLYLEELAELGAADFGTLQKIQIPLIYAYCDTGQYREAESLAEQIVSNQAKLAEHNKTGASTKSEDYLRALEVAVYVQKSEDHLNLAEERLTTLHAQAPFNNDIRTSWASLLLARDHPHAALDEYSMMVLDVPSSLDANIGRGEILLSQNELSQAKNILPPLIDNYPENKVVLHYSRQLESYSQPFYRIETTIGRGAAQGGADSVASAIIYSAPFNLEPNPESNEFATDSWSSNRFRLFTQLSYAEGETVNNVNASRSRLSAGMDYRASDITAEASVNHTVNDNRNNGIALAMSLTISDNWHTRAAVDTNIIDLPAAALNLGVTAKQETLEIDWSKNESRKAGGELSSTQFSDSNVRDFAHLWWQERWISEPVFKLDTVLGVSASTNSQMNLAYFNPPHDKELDLDIKGDWLTWRHYQRSFKQRFDFSVGQYSQSGFGSGATAGLRYEHEWAFENELAFTYGLGRNFHPYDGEREYRNYIYLNLSGRIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSJ4</accession>
    <name>A0A2S9GSJ4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="10">GGDEF: diguanylate cyclase (GGDEF) domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">S2091_4633</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000039">
        <property type="protein sequence ID" value="PRC90683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90683">
        <property type="protein sequence ID" value="PRC90683"/>
        <property type="gene ID" value="S2091_4633"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01948">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001633">
        <property type="entry name" value="EAL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035919">
        <property type="entry name" value="EAL_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033480">
        <property type="entry name" value="sCache_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00563">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17200">
        <property type="entry name" value="sCache_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01049">
        <property type="entry name" value="Cache_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00052">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141868">
        <property type="entry name" value="SSF141868"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50883">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="205"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="8">
        <location>
            <begin position="225"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="9">
        <location>
            <begin position="309"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="domain" description="EAL" evidence="7">
        <location>
            <begin position="456"/>
            <end position="710"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC90683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="712" mass="79366" checksum="71D483A12AB3D9AE" modified="2018-07-18" version="1">MGEESVFIMPFSRLSVAARFLLVLLIGFIFQAGISVISLLDLKRSMMQERTSEVKHLLDTGYSTLVYFHNQASNGRMTDEEARHAARDAVRAMHYDGNNYYFIWDLDGNGIAHGGNVKYEGKNFFTGPDAKTNPVVAYMVHRLINVARSPDKEGTTTYRIPKAGQTIPLDKLSYSRLFEPWGWSIGTGVYIDDIDETFRMQAIRLLWIFLGMFTLATGVTYFIWHDLLLAMRRLAVRIESITKGELDSEIPDLDRHDEVGVMARALLVLRDTSKEVSELKLDHLTGLPTRKLLMDRIRQTKIRSARSGMYNSLLLIDLDKFKPLNDTHGHNAGDQMLKEVAKRLIASVRVSDTVARLGGDEFIVLLADINENEAVALEVSKKIAGKIVDTLNQNYHLGHITHHGTASIGATLFKGNSLAADDLLKQADIAMYKSKIMGSNTCQFFETDMKATGHEQITLEKELRNGIAQKQFLFHYQSQAGGNGQLLGCEALLRWQHPSRGLLAPSEFLPLAEKTGLIAPLGQLALDMACGQLALWASHPELAALSVAVNVSSIQFRRPEFVEQVLAVLQRTGAEPHRLKLELSEHLLANNVPCVIEKMSVLKLQGVRFALDDFGRSYSSLSHLNQLPLNELKIERAFVHDVLTNNNDAAMAKMIVALAKILGLHVIAVGVETEAQKEFLSEAGCVEYQGYLHSHPLPVDEFELQVLKTKLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSR4</accession>
    <name>A0A2S9GSR4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glutathione S-transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_4571</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000037">
        <property type="protein sequence ID" value="PRC90745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90745">
        <property type="protein sequence ID" value="PRC90745"/>
        <property type="gene ID" value="S2091_4571"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14497">
        <property type="entry name" value="GST_C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02798">
        <property type="entry name" value="GST_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="SSF47616"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GST N-terminal" evidence="1">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="2">
        <location>
            <begin position="85"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC90745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="195" mass="22059" checksum="91AA41C48EC64ACF" modified="2018-07-18" version="1">MKLYFTPRSSATRPRWLLEELGVPYELVKLDFAQREHQTAAYLQLHPFGEVPALVDGDLRLFESLAICFYLADYSPEAQLAPSLGSPERARYMQWLIFAETRLEPVVKQFLNHSNSPEPANAQIYASLNHVLGIIDTELDGRDFIAAGHFTAADLVLASILHLANAMKLLEGYPRLVKYVYFHCQRPALQRAVTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSS8</accession>
    <name>A0A2S9GSS8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4574</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AHA1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000037">
        <property type="protein sequence ID" value="PRC90748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90748">
        <property type="protein sequence ID" value="PRC90748"/>
        <property type="gene ID" value="S2091_4574"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013538">
        <property type="entry name" value="Activator_of_Hsp90_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08327">
        <property type="entry name" value="AHSA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="153" mass="17923" checksum="5A362915C68A8FEC" modified="2018-07-18" version="1">MMTMDEKDRELVLERMIPFARELVWKAMTDPEHVNRWWGPDGFRNENQIMDFRVGGAWSYEMVGPDGKRYPSHSVFKEITPPSRLVFDHGDGERMWFETTITLQEIDSGTLISLRQLYPSRESRDEVIDKYGAVEGGKQHLAKLEAYVRENLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSU6</accession>
    <name>A0A2S9GSU6_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Flagellar brake protein YcgR</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Cyclic di-GMP binding protein YcgR</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ycgR</name>
        <name evidence="7" type="ORF">S2091_4523</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)-dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Monomer. Interacts with the flagellar basal bodies.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Bacterial flagellum basal body</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the YcgR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000036">
        <property type="protein sequence ID" value="PRC90775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90775">
        <property type="protein sequence ID" value="PRC90775"/>
        <property type="gene ID" value="S2091_4523"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009425">
        <property type="term" value="C:bacterial-type flagellum basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035438">
        <property type="term" value="F:cyclic-di-GMP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071973">
        <property type="term" value="P:bacterial-type flagellum-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071945">
        <property type="term" value="P:regulation of bacterial-type flagellum-dependent cell motility by regulation of motor speed"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01457">
        <property type="entry name" value="YcgR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009875">
        <property type="entry name" value="PilZ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023787">
        <property type="entry name" value="T3SS_YcgR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009926">
        <property type="entry name" value="T3SS_YcgR_PilZN"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07238">
        <property type="entry name" value="PilZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07317">
        <property type="entry name" value="YcgR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0975">Bacterial flagellum</keyword>
    <keyword evidence="1 4" id="KW-0973">c-di-GMP</keyword>
    <keyword evidence="7" id="KW-0966">Cell projection</keyword>
    <keyword evidence="7" id="KW-0969">Cilium</keyword>
    <keyword evidence="7" id="KW-0282">Flagellum</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="T3SS_YcgR_PilZN" evidence="6">
        <location>
            <begin position="16"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="PilZ" evidence="5">
        <location>
            <begin position="124"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01457"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF07317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC90775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="253" mass="28390" checksum="3D3C9674ECC97A7C" modified="2018-07-18" version="1">MIPTSPVLGTENQSPYQVDSRKEIILLLRSLQENKQLINMIIHDGNEVIITAILKVDDDNNNIIFDCASTESANQRLIEAPRVYFEAALNKIGIQFSSSSVSRCNFMGSPSLCCTIPSSLIRLQRREYYRINTPHTHPLICVVNVPEENGGGKINLPLVDISCGGVAMLDDQRVLNVDFGTLYNDCKIDLPGIGLVNITLQVRNSQNLLLMNHKTSRRIGFQFIDLSKTMMAQIQKLITKIERERNSRQSGMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GT27</accession>
    <name>A0A2S9GT27_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Terminase-like family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_4444</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000034">
        <property type="protein sequence ID" value="PRC90863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90863">
        <property type="protein sequence ID" value="PRC90863"/>
        <property type="gene ID" value="S2091_4444"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019069">
        <property type="term" value="P:viral capsid assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010332">
        <property type="entry name" value="ATPase_terminase-su_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035421">
        <property type="entry name" value="Terminase_6C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06056">
        <property type="entry name" value="Terminase_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17289">
        <property type="entry name" value="Terminase_6C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Terminase_6C" evidence="2">
        <location>
            <begin position="462"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="156"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="165"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC90863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="638" mass="72972" checksum="168753F9DE244E0E" modified="2018-07-18" version="1">MIEGSIVKVVRCLFNWQRVSKGLTDFPASPLRTRKPYAGGMSETPTELPPVSEPNLAPETDPRRLAKQLYWQGWRVTSIANYLKLKRTTVHSWKERDEWDKASPLEKIESSLEARMVQLIVKEAKTGGDFKEIDLLGRQVERLARVRRYEAPGGNEVDLNPKLANRNAGEKKKPTRNDFSDEQRDQLLEAFQDSLFDYQKVWFRNGHQRTRAILKSRQIGATWYFAREALADAMKTGRNQIFLSASKAQAHVFKQYIIQFAQESAGITLTGDPIVLPNGAHLYFLGTNARTAQGYHGNFYFDEFFWTHNFQELNKVASGMAIHKQWRKTYFSTPSSITHQAYPFWTGDAFNKRRAKNDRIDIDVSHRRLSSGFVGEDKIWRQIVTILDAEAGGCDLFNIDELRDFEYSPDQFDNLLMCNFIDDTQSVFPLTALQRCMIDSWVSWDDYKPFSPRPFGHRPVWIGYDPSLTGDSAGCVVMAPPLVEGGKFRILERFQWRGIDFEAQAKAIKEMTERYNVTYIGIDTTGMGIGVFPLVKQFFPLVTSINYSPEVKTRMVLKAQNIISKARLEFDAGWTDIAQSFMTIRKTLTTSGRQVTYDAGRTDETGHADLAWACMHALDNEPFEGTNGNHQSIIEIYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GT56</accession>
    <name>A0A2S9GT56_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4386</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000033">
        <property type="protein sequence ID" value="PRC90893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90893">
        <property type="protein sequence ID" value="PRC90893"/>
        <property type="gene ID" value="S2091_4386"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021233">
        <property type="entry name" value="DUF2783"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10932">
        <property type="entry name" value="DUF2783"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC90893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="66" mass="7480" checksum="B614E9AE396AE32B" modified="2018-07-18" version="1">MSINTAPNITNHDLFYDWLIQCHHDLTNDQSQAMNAQLILILANHIGDLATLLEAMTLARDGVRHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GT80</accession>
    <name>A0A2S9GT80_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Plasmid stabilization system protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4399</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000033">
        <property type="protein sequence ID" value="PRC90906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90906">
        <property type="protein sequence ID" value="PRC90906"/>
        <property type="gene ID" value="S2091_4399"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2310.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007712">
        <property type="entry name" value="RelE/ParE_toxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035093">
        <property type="entry name" value="RelE/ParE_toxin_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05016">
        <property type="entry name" value="ParE_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-1277">Toxin-antitoxin system</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="107" mass="12306" checksum="7D788AEA149E7C54" modified="2018-07-18" version="1">MPTVYTREAARQDLIERYAYLAENASLTIAERFLVNAETSFANLSQQPMLGTPLSLNNLELIGMRKWSVKNFDNILIFYLPRHDGVSIVRVLHGAQQWWELLGVLEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTA7</accession>
    <name>A0A2S9GTA7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">PqqD family protein, HPr-rel-A system</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4344</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000032">
        <property type="protein sequence ID" value="PRC90943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90943">
        <property type="protein sequence ID" value="PRC90943"/>
        <property type="gene ID" value="S2091_4344"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027599">
        <property type="entry name" value="PqqD-rel_X"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04353">
        <property type="entry name" value="PqqD_rel_X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC90943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="90" mass="9884" checksum="5E75C0328EB83E99" modified="2018-07-18" version="1">MKWRTVTTTANNLRIWGDEYVVYNPQSGSTHLLGLAAGQILQKLEISPLDVSSLASLLGAEWQQEAEPDFVQSVQNLLTDLQALALIECA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTM0</accession>
    <name>A0A2S9GTM0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_4260</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000030">
        <property type="protein sequence ID" value="PRC91072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91072">
        <property type="protein sequence ID" value="PRC91072"/>
        <property type="gene ID" value="S2091_4260"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015562">
        <property type="term" value="F:efflux transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003423">
        <property type="entry name" value="OMP_efflux"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010131">
        <property type="entry name" value="RND_efflux_OM_lipoprot_NodT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02321">
        <property type="entry name" value="OEP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01845">
        <property type="entry name" value="outer_NodT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0564">Palmitate</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1134">Transmembrane beta strand</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU362097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="513" mass="55062" checksum="9515688DCEFFFBA3" modified="2018-07-18" version="1">MGMIIKTFAGIGLVFLTGCAVKGPNFSPPESHLSTTWNVDQSVDTRAVVTTNVATNPLADPDPNWWHSFNDTLLDSLEQRAVAGNLDLQVALLRIAASRSQEQIARAQGLPNLKAAASYDREQLGLEGILKSAGPLPPSLQNNPATGPIESQLTDPINLYTVALDASWELDLFGKVTRSVEAAAAQSHANEEARNGALVALQAEVAQTYAQLRAAQALRALTIKELSDEQQILDLTKDLQKSGLGNQSDVESLVSQVAQNQALLPQYEIQITQTCNALAVLIGVNPGTLNAELTIDGKIIALPDVIAIGVPASLARRRPDIREAEENLHAATAETGVAIASLYPDLSLGAQYGLRNTTTKYLFNWASRFYSVGPSISLPIFQGGSLTANVHLAKAEQAAAAIMYRKTVLNALQEVENALISFHQDQLRAQSLKTATQANNRALALNSNAYQHGLINFITVLNSERQAVQTQTQWTTAQVQLSTDLITLYKALGGGWEINPPIIAADIESNGLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTT1</accession>
    <name>A0A2S9GTT1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_4204</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000029">
        <property type="protein sequence ID" value="PRC91108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91108">
        <property type="protein sequence ID" value="PRC91108"/>
        <property type="gene ID" value="S2091_4204"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002123">
        <property type="entry name" value="Plipid/glycerol_acylTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01553">
        <property type="entry name" value="Acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00563">
        <property type="entry name" value="PlsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="domain" description="PlsC" evidence="2">
        <location>
            <begin position="66"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="245" mass="27293" checksum="0A744FAA8480AB64" modified="2018-07-18" version="1">MNKLRYYLQICRVAVHLVRGLLICFLLFPWLSKEAKQSRIQIWSQQLLAVFNVRVKMNLASMPTGSVIISNHISWLDIFVINSLAPCRFVAKSDIRSWPMLGWLAEQAGTIYISRGSKSDVKRIYQYLIDQIEAGERVAFFPEGTTAAQGVVLPFHANLFEAAIHAKVPIQPFTLRYLNAAGELHHAVDFTGDMTFAASMDNILNGGEVVVELQSLEPISSIGAHRRELASAARLAVAEALQVDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTV9</accession>
    <name>A0A2S9GTV9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4168</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000028">
        <property type="protein sequence ID" value="PRC91167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91167">
        <property type="protein sequence ID" value="PRC91167"/>
        <property type="gene ID" value="S2091_4168"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="95"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="133" mass="15222" checksum="6CD3859C3E35BC88" modified="2018-07-18" version="1">MAIKLHGWRRIALVLSVSWITVTASFAAANYFGGSDGYFVYQSMPMGSKIEGNVVTFQDGRKVRLPIEPDTKPWEVDWSKQVGVPKLPEIRWPRFLIIGIFFPFLLWLFVEISAVVVRWIAVGFRDSKSRSDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTY0</accession>
    <name>A0A2S9GTY0_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Formate-dependent phosphoribosylglycinamide formyltransferase</fullName>
            <ecNumber evidence="3">6.3.1.21</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">5'-phosphoribosylglycinamide transformylase 2</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Formate-dependent GAR transformylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">GAR transformylase 2</fullName>
            <shortName evidence="3">GART 2</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Non-folate glycinamide ribonucleotide transformylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Phosphoribosylglycinamide formyltransferase 2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">purT</name>
        <name evidence="6" type="ORF">S2091_4082</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>ATP + formate + N(1)-(5-phospho-beta-D-ribosyl)glycinamide = ADP + H(+) + N(2)-formyl-N(1)-(5-phospho-beta-D-ribosyl)glycinamide + phosphate</text>
            <dbReference type="Rhea" id="RHEA:24829"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:143788"/>
            <dbReference type="ChEBI" id="CHEBI:147286"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.1.21"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Purine metabolism; IMP biosynthesis via de novo pathway; N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide from N(1)-(5-phospho-D-ribosyl)glycinamide (formate route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the PurK/PurT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.1.21" evidence="3"/>
    <dbReference type="EMBL" id="PUGF01000027">
        <property type="protein sequence ID" value="PRC91187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91187">
        <property type="protein sequence ID" value="PRC91187"/>
        <property type="gene ID" value="S2091_4082"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00127"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043815">
        <property type="term" value="F:phosphoribosylglycinamide formyltransferase 2 activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004644">
        <property type="term" value="F:phosphoribosylglycinamide formyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01643">
        <property type="entry name" value="PurT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003135">
        <property type="entry name" value="ATP-grasp_carboxylate-amine"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005862">
        <property type="entry name" value="PurT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011054">
        <property type="entry name" value="Rudment_hybrid_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02222">
        <property type="entry name" value="ATP-grasp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51246">
        <property type="entry name" value="SSF51246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="SSF52440"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01142">
        <property type="entry name" value="purT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1 3" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ATP-grasp" evidence="5">
        <location>
            <begin position="139"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="region of interest" description="5'-phosphoribosylglycinamide binding" evidence="3">
        <location>
            <begin position="41"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="5'-phosphoribosylglycinamide binding" evidence="3">
        <location>
            <begin position="387"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="101"/>
        </location>
        <ligand>
            <name>N(1)-(5-phospho-beta-D-ribosyl)glycinamide</name>
            <dbReference type="ChEBI" id="CHEBI:143788"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="134"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="175"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="180"/>
            <end position="185"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="215"/>
            <end position="218"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="223"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="292"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="304"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="311"/>
        </location>
        <ligand>
            <name>N(1)-(5-phospho-beta-D-ribosyl)glycinamide</name>
            <dbReference type="ChEBI" id="CHEBI:143788"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="380"/>
        </location>
        <ligand>
            <name>N(1)-(5-phospho-beta-D-ribosyl)glycinamide</name>
            <dbReference type="ChEBI" id="CHEBI:143788"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC91187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="418" mass="45182" checksum="D354B64C65A5C7D1" modified="2018-07-18" version="1">MLQCFLQNMNKSSNSANNISVQIGTPLSHSATKVMLLGSGELGKEVIISLQRLGVEVIAVDRYADAPGHQVAHRSHVIDMTDGVALANLIAVEQPDLIVPEIEAIATLTLVELEAAGKVRVIPTARATWLTMNREGIRRLVAEELSLPTSPYRFADTLEEMRAACDFIGYPCIIKPVMSSSGKGQSKIDNASEVDAAWEYAASGGRVQNGRVIVEGFIDFDYEITLLTVRALDANGQPATHYCEPIGHVQVQGDYVESWQPQAMHPQALENARNIAKKVTDNLGGLGLFGVELFVKNEMVWFSEVSPRPHDTGMVTMASQVQNEFELHAKAILGLPVDTSLRCPAASAVIYGEHNARAIAFQGVADALSVPGTDIRLFGKPESFTRRRMGVTLATAPDTDTARTKAKQAAAKVKPVVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GU18</accession>
    <name>A0A2S9GU18_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4094</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000027">
        <property type="protein sequence ID" value="PRC91199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91199">
        <property type="protein sequence ID" value="PRC91199"/>
        <property type="gene ID" value="S2091_4094"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="75" mass="8380" checksum="3C32D5468F52D783" modified="2018-07-18" version="1">MILDEEKIEEQVGEKLDAWLDRADKDIEAAVNRGLAVALLEGVSAGAKVMYEEGVPVEISTRVLTNHKRRSSDWQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUG5</accession>
    <name>A0A2S9GUG5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3920</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000024">
        <property type="protein sequence ID" value="PRC91375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91375">
        <property type="protein sequence ID" value="PRC91375"/>
        <property type="gene ID" value="S2091_3920"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006334">
        <property type="term" value="P:nucleosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005819">
        <property type="entry name" value="H1/H5"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00624">
        <property type="entry name" value="HISTONEH5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="89"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="305" mass="29142" checksum="D68701FE039D6384" modified="2018-07-18" version="1">MSTASKPAKKAAAAPKKAAAAPKKPVAVKAAAKPAVKKVAAKPAAKVAAKPAAKKVAAKPAAKVAAKPAAKKAVAKVAAKPAAKKVAAKPAAKKVAAKPAAKKVVAKPAAKKVAAKPAAKKVAAKPAAKKAAAKPAAKKVAAKPAAKKVAAKPAAKKVAAKPAAKKVAAKPAAKKVAAKPAAKKVAAKPAAKKAAAKPAAKKAVAKPAAKKAAAKPAAKVAAKPAAKAAPKKAAAKPAAKAAAKPAAKAAAKPAAKVVAKPAAKKPAAKKAAAKPAVKPAAAKEANSVIAPTAAWPFPTATPRPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUK7</accession>
    <name>A0A2S9GUK7_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DNA gyrase inhibitor YacG</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">yacG</name>
        <name evidence="2" type="ORF">S2091_3945</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="1">Binds 1 zinc ion.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Interacts with GyrB.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA gyrase inhibitor YacG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000024">
        <property type="protein sequence ID" value="PRC91400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91400">
        <property type="protein sequence ID" value="PRC91400"/>
        <property type="gene ID" value="S2091_3945"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008657">
        <property type="term" value="F:DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.50.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00649">
        <property type="entry name" value="DNA_gyrase_inhibitor_YacG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005584">
        <property type="entry name" value="DNA_gyrase_inhibitor_YacG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013088">
        <property type="entry name" value="Znf_NHR/GATA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36150">
        <property type="entry name" value="PTHR36150"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03884">
        <property type="entry name" value="YacG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <feature type="binding site" evidence="1">
        <location>
            <position position="5"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="8"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="24"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="28"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="58" mass="6695" checksum="EFE635659B57DA11" modified="2018-07-18" version="1">MIVDCPQCSKKVVWDTKNPYRPFCSERCKQIDLGAWAEESYVITSTAPEPDDLQDEEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUK8</accession>
    <name>A0A2S9GUK8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Putative Mg2+ and Co2+ transporter CorB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">S2091_3939</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000024">
        <property type="protein sequence ID" value="PRC91394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91394">
        <property type="protein sequence ID" value="PRC91394"/>
        <property type="gene ID" value="S2091_3939"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04590">
        <property type="entry name" value="CBS_pair_CorC_HlyC_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002550">
        <property type="entry name" value="CNNM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044751">
        <property type="entry name" value="Ion_transp-like_CBS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005170">
        <property type="entry name" value="Transptr-assoc_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03471">
        <property type="entry name" value="CorC_HlyC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01595">
        <property type="entry name" value="DUF21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01091">
        <property type="entry name" value="CorC_HlyC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="SSF56176"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51846">
        <property type="entry name" value="CNNM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0129">CBS domain</keyword>
    <keyword evidence="6 8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 8 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="38"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="70"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="109"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="domain" description="CNNM transmembrane" evidence="11">
        <location>
            <begin position="1"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="10">
        <location>
            <begin position="187"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="10">
        <location>
            <begin position="254"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PRC91394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="400" mass="44936" checksum="EE7F73F0E61FFC4C" modified="2018-07-18" version="1">MTETALMAANRHRLRHLAKRGNKNAITTLWLLDRVEKLLAVILIANTLFNALSTALVTVIAISTFGNNDTVITIATATVTFLLIVFAEISPKVIGATYPERIALPASFILKPLMTIGLPVTWFVNLFVSTLLKTLRIKTGNAVQEARLSPEELRSMILEGGNFIPQKHKSILLNLFDLESISVEDVMTPRSQIEALDFSVSVEDIKHQLTTCYHSKLPVYEGEINRIIGILHVRKAIALLNQEHELTTQDFRQLLTPPYFIPEDTGVFTQLQYFQEKRERLGIIIDEYGEVQGLVTLDDIIEEMIGEFTTSVPGDARADAFNWDKQGQCVLEGTTTLRDINKRLHLDFPIDGPKTLNGLLLEILQDIPEAQVSLKIKNCVVEIIQVQNQAIKVVKIYQQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUR1</accession>
    <name>A0A2S9GUR1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Pro-kumamolisin, activation domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_3865</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
        <text evidence="3">Binds 1 Ca(2+) ion per subunit.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000023">
        <property type="protein sequence ID" value="PRC91450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91450">
        <property type="protein sequence ID" value="PRC91450"/>
        <property type="gene ID" value="S2091_3865"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04056">
        <property type="entry name" value="Peptidases_S53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11377">
        <property type="entry name" value="Pro-peptidase_S53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015366">
        <property type="entry name" value="S53_propep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030400">
        <property type="entry name" value="Sedolisin_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09286">
        <property type="entry name" value="Pro-kuma_activ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00944">
        <property type="entry name" value="Pro-kuma_activ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="SSF52743"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51695">
        <property type="entry name" value="SEDOLISIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0106">Calcium</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="Peptidase S53" evidence="4">
        <location>
            <begin position="219"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="3">
        <location>
            <position position="290"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="3">
        <location>
            <position position="294"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="3">
        <location>
            <position position="482"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="522"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="523"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="536"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="538"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC91450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="556" mass="58663" checksum="B5B05CE454813863" modified="2018-07-18" version="1">MIKFPIIFALFICGILTKLNYGSMEFQTNFKFIFLMKKVIMTINSVRSVIPGTNRIPMRNAQVVGPIPENQIIEITIMLRSEHECKDLNTQFMSGNQSLSKRKILSREEFAKKFGASSADIAKVEAFAQQYNLAVCKVNQAHRSIILSGTVGALNKAFGTTLEQYQHPNGVYFGRIGELSAPNDVIEMIEGVFGLDNRPQASKHFQVRTSTDTIKPSTTFTPPQLAKIYNFPPADATGQCIGIIELGGGTRPADINAYFSGLGITAPNVIIVPVDSATDQPSTPAGADGEVMLDIEVAGAIAPGATIAVYFAPNTDRGFLDAVTTAIHDAVNKPSVISISWGSAEVAWTHQAMTAFESAFIDAAAMGVTICVAAGDNGSTDGQTDGTQNVDFPASAPHALACGGTSLVINAAGSATETVWNDGVNSATGGGHSSFFPIPAYQTSLDFTQQGRGVPDVAADADPNTGYAVRVDGEDMVIGGTSAVAPLWAGLIALINQQLGHPVGFLNPLLYGALQNKKVTNDITQGNNGAYQAGVGWDACTGWGSPNGQNLLHALD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUV3</accession>
    <name>A0A2S9GUV3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Major Facilitator Superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3790</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000022">
        <property type="protein sequence ID" value="PRC91512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91512">
        <property type="protein sequence ID" value="PRC91512"/>
        <property type="gene ID" value="S2091_3790"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="68"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="93"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="125"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="168"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="229"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="264"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="293"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="316"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="357"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="380"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="420" mass="45327" checksum="99490520BEB173AE" modified="2018-07-18" version="1">MNRGFYTIMGAQFFSSLADNALLIAAFYALAEMNAPEWMTPMLKFFFVASYVLLAAFVGAFSDSMPKGRVMFITNVIKIVGCGLMFVHVHPLVAYGVVGIGAAAYSPAKYGILTELLPAEKLVAANGWIEGLTVASIILGAGLGGALINPQVSATLLSFKLPLIHSYITTPLEAALSIVMVLYIAATIFNLYIPDTGARYTKQATNPIELVTDFGHCCAMLWRDKLGQITLAITTLFWGAGAVLQFLVIYWAQVSLKLPLDKAAVIPAVSAIGIAFGAIAAGRYVPIKKSLSVMPYGVAMGVVVMSMTMVHSVWVAYPLLVIIGALSGFFVVPMNALLQHRGHVLMSAGHSISVQNFNENVSILIMMVMYTLMVKSDLSINIIIVAFGLFVSSSTLMVMRKHRANQREHDSLALIGEHKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GV46</accession>
    <name>A0A2S9GV46_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acetyltransferase including N-acetylase of ribosomal protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3694</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000021">
        <property type="protein sequence ID" value="PRC91578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91578">
        <property type="protein sequence ID" value="PRC91578"/>
        <property type="gene ID" value="S2091_3694"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="14"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="185" mass="21179" checksum="0CDB4D87ADF43552" modified="2018-07-18" version="1">MPQFDLVTISTQRLLLRPMQPSDAAALFAIHSNEEVMRYWSSLPWTSIEVAHERIARDLRAMQAGEYLDLAIVRIEDDLLIGSCTLFRLDEQCRRAEMGYALLHDAWGFGYMNEALQALLKFGFTELALNRVEADIDPRNTGSAKTLERLGFQEEGYLRERWIVDGVSSDSAIYGLLFSDWQARQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GV64</accession>
    <name>A0A2S9GV64_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Glutamate dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">S2091_3738</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:11612"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.4.1.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3 5 9">Belongs to the Glu/Leu/Phe/Val dehydrogenases family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000021">
        <property type="protein sequence ID" value="PRC91622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91622">
        <property type="protein sequence ID" value="PRC91622"/>
        <property type="gene ID" value="S2091_3738"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004353">
        <property type="term" value="F:glutamate dehydrogenase [NAD(P)+] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:cellular amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01076">
        <property type="entry name" value="NAD_bind_1_Glu_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminiacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006095">
        <property type="entry name" value="Glu/Leu/Phe/Val_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033524">
        <property type="entry name" value="Glu/Leu/Phe/Val_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006096">
        <property type="entry name" value="Glu/Leu/Phe/Val_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006097">
        <property type="entry name" value="Glu/Leu/Phe/Val_DH_dimer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014362">
        <property type="entry name" value="Glu_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033922">
        <property type="entry name" value="NAD_bind_Glu_DH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00208">
        <property type="entry name" value="ELFV_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02812">
        <property type="entry name" value="ELFV_dehydrog_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000185">
        <property type="entry name" value="Glu_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00082">
        <property type="entry name" value="GLFDHDRGNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00839">
        <property type="entry name" value="ELFV_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="SSF53223"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00074">
        <property type="entry name" value="GLFV_DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0520">NAD</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 5 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ELFV_dehydrog" evidence="10">
        <location>
            <begin position="194"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="6">
        <location>
            <position position="117"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="81"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="105"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="201"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="232"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="361"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Important for catalysis" evidence="8">
        <location>
            <position position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR000185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000185-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000185-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000185-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC91622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="428" mass="46457" checksum="6A0C7E6360668406" modified="2018-07-18" version="1">MIPQHEVPSYLTPHEIGPWGDYLTQIERVTPYLGSLSRWVETLKRPKRILVVDVPIERDNGTIAHFEGYRVQHNTSRGPGKGGVRFHQNVTLSEVMALSAWMTIKNAAVNVPYGGAKGGIRVDPKTLSQGELQRMTRRYTSEIGIIIGPNKDIPAPDVNTNEQTMAWMMDTYSMNEGATATGVVTGKPISLGGSLGRREATGRGVYVVGSAAAHTIGLNIEGAKIAVQGFGNVGGISAKLFAEAGAKIVAVQDHAGTVFHSNGLNVPKLLAHVAEFGSVVGFSGSEEKMSRDNFWDVDCDIMIPAALEQQITETNAHRIRAKIILEGANGPTTPQADDILHAKGVLVVPDVLANAGGVTVSYFEWVQDFSSYFWSEDEINSRLTRIMTEAFNAVRQVSVDKEVSLRTAAFLIGCTRVLQAREMRGLYP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GV69</accession>
    <name>A0A2S9GV69_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3672</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000021">
        <property type="protein sequence ID" value="PRC91556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91556">
        <property type="protein sequence ID" value="PRC91556"/>
        <property type="gene ID" value="S2091_3672"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12802">
        <property type="entry name" value="MarR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00598">
        <property type="entry name" value="HTHMARR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00347">
        <property type="entry name" value="HTH_MARR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50995">
        <property type="entry name" value="HTH_MARR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="1">
        <location>
            <begin position="13"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="151" mass="16808" checksum="129CEA4E3611EB12" modified="2018-07-18" version="1">MTNSLDVPGYQQQAQAARLLYRAQIEFVDALDKELAQYDMTAAQYAIVAALASGRASSVGQICKELAYDTGAMTRMLDRMERKDILRRVRSVEDRRSVMVELTPHGKSIYPELLASSSKVMASFFGHFSASELDQLEGLLSRVTPRVSPVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GV82</accession>
    <name>A0A2S9GV82_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Thiamine-phosphate synthase</fullName>
            <shortName evidence="8">TP synthase</shortName>
            <shortName evidence="8">TPS</shortName>
            <ecNumber evidence="8">2.5.1.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Thiamine-phosphate pyrophosphorylase</fullName>
            <shortName evidence="8">TMP pyrophosphorylase</shortName>
            <shortName evidence="8">TMP-PPase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">thiE</name>
        <name evidence="12" type="ORF">S2091_3724</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8 9">
            <text>2-(2-carboxy-4-methylthiazol-5-yl)ethyl phosphate + 4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + 2 H(+) = CO2 + diphosphate + thiamine phosphate</text>
            <dbReference type="Rhea" id="RHEA:47848"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37575"/>
            <dbReference type="ChEBI" id="CHEBI:57841"/>
            <dbReference type="ChEBI" id="CHEBI:62890"/>
            <dbReference type="EC" id="2.5.1.3"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3 8 9">
            <text>2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate + 4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + 2 H(+) = CO2 + diphosphate + thiamine phosphate</text>
            <dbReference type="Rhea" id="RHEA:47844"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37575"/>
            <dbReference type="ChEBI" id="CHEBI:57841"/>
            <dbReference type="ChEBI" id="CHEBI:62899"/>
            <dbReference type="EC" id="2.5.1.3"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 8 9">
            <text>4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + 4-methyl-5-(2-phosphooxyethyl)-thiazole + H(+) = diphosphate + thiamine phosphate</text>
            <dbReference type="Rhea" id="RHEA:22328"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37575"/>
            <dbReference type="ChEBI" id="CHEBI:57841"/>
            <dbReference type="ChEBI" id="CHEBI:58296"/>
            <dbReference type="EC" id="2.5.1.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="8">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4 8 10">Cofactor biosynthesis; thiamine diphosphate biosynthesis; thiamine phosphate from 4-amino-2-methyl-5-diphosphomethylpyrimidine and 4-methyl-5-(2-phosphoethyl)-thiazole: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8 9">Belongs to the thiamine-phosphate synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.3" evidence="8"/>
    <dbReference type="EMBL" id="PUGF01000021">
        <property type="protein sequence ID" value="PRC91608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91608">
        <property type="protein sequence ID" value="PRC91608"/>
        <property type="gene ID" value="S2091_3724"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00060">
        <property type="reaction ID" value="UER00141"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004789">
        <property type="term" value="F:thiamine-phosphate diphosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009228">
        <property type="term" value="P:thiamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009229">
        <property type="term" value="P:thiamine diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00564">
        <property type="entry name" value="TMP_TenI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00097">
        <property type="entry name" value="TMP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036206">
        <property type="entry name" value="ThiamineP_synth_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022998">
        <property type="entry name" value="ThiamineP_synth_TenI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034291">
        <property type="entry name" value="TMP_synthase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02581">
        <property type="entry name" value="TMP-TENI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51391">
        <property type="entry name" value="SSF51391"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00693">
        <property type="entry name" value="thiE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 8 9" id="KW-0784">Thiamine biosynthesis</keyword>
    <keyword evidence="5 8 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TMP-TENI" evidence="11">
        <location>
            <begin position="8"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="HMP-PP binding" evidence="8">
        <location>
            <begin position="37"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="THZ-P binding" evidence="8">
        <location>
            <begin position="185"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="69"/>
        </location>
        <ligand>
            <name>4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine</name>
            <dbReference type="ChEBI" id="CHEBI:57841"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="70"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="89"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="108"/>
        </location>
        <ligand>
            <name>4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine</name>
            <dbReference type="ChEBI" id="CHEBI:57841"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="138"/>
        </location>
        <ligand>
            <name>4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine</name>
            <dbReference type="ChEBI" id="CHEBI:57841"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="165"/>
        </location>
        <ligand>
            <name>2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:62899"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PRC91608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="206" mass="22181" checksum="6CA6DB8FFF719691" modified="2018-07-18" version="1">MNTNLTGLYLVTPDWDDTNQLLEISELALKGGASLLQYRHKTADGQLRKQQATALLELCRAYHCPFIINDHVELCMELDADGIHVGGLDASVAQVRAAVGPNKIVGASCYGDMQLAHTAQQQGASYVAFGGFYPSRIKKYPVTTPHNIVTQAKLEIALPNVVIGGMTIENCQPLVTAGADMVAAISSVYMAENPELAARGFCDLFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVA6</accession>
    <name>A0A2S9GVA6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major Facilitator Superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_3600</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000020">
        <property type="protein sequence ID" value="PRC91662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91662">
        <property type="protein sequence ID" value="PRC91662"/>
        <property type="gene ID" value="S2091_3600"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="21"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="78"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="111"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="137"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="170"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="210"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="268"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="319"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="353"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="377"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="414"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="453"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="514"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="27"/>
            <end position="477"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC91662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="544" mass="58452" checksum="F72AFF3646C4CB11" modified="2018-07-18" version="1">MSFMHVFSKEHIIAGAGFNRWLVPPAALAIHLCIGMAYGFSVFWLPLSRAVGITSSVACAKELSFFETLFATNCDWKISSLVVMFQLFFIFLGGAAALFGGWLEHAGPRKAGVVAALCWCGGLVISAFGIYVHQILLVWLGAGVIGGIGLGLGYISPVSTLIKWFPDRRGMATGMAIMGFGGGAMVGAPLADWLMRHFSSATSVGVWETFLTMAVIYFVFMIGGAFAYRIPATGWTPVGWTAPVAQINNVMITNQHVHLAKAWRTPQFWLIWGVLCLNVTAGIGIIGMASPLLQEVFGGHLIGVDLGFNALNLAQKAQIATIAAGFTGLLSLFNIGGRFFWASLSDLIGRKMTYFAFFVIGFILYAAIPTIGRSGHLPLFVLSFCIILSMYGGGFATVPAYLADMFGSQMVGAIHGRLLTAWATAGVLGPLVVNYIREYQLGNGVPKAQAYDVTMYVLAGMLALGFICNLLIRPVSKDKFMTAEELAHERQLAHDKAVTLSMAGTNEVVSSNSVLVAILAWSAVGIPLLFGIWITLQKALILFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVA7</accession>
    <name>A0A2S9GVA7_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Purine nucleoside phosphorylase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">S2091_3579</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>adenosine + H(+) + H2O = inosine + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:24408"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16335"/>
            <dbReference type="ChEBI" id="CHEBI:17596"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="EC" id="3.5.4.4"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="4">
            <dbReference type="Rhea" id="RHEA:24409"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>adenosine + phosphate = adenine + alpha-D-ribose 1-phosphate</text>
            <dbReference type="Rhea" id="RHEA:27642"/>
            <dbReference type="ChEBI" id="CHEBI:16335"/>
            <dbReference type="ChEBI" id="CHEBI:16708"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57720"/>
            <dbReference type="EC" id="2.4.2.1"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="2">
            <dbReference type="Rhea" id="RHEA:27643"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>inosine + phosphate = alpha-D-ribose 1-phosphate + hypoxanthine</text>
            <dbReference type="Rhea" id="RHEA:27646"/>
            <dbReference type="ChEBI" id="CHEBI:17368"/>
            <dbReference type="ChEBI" id="CHEBI:17596"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57720"/>
            <dbReference type="EC" id="2.4.2.1"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="1">
            <dbReference type="Rhea" id="RHEA:27647"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>phosphate + S-methyl-5'-thioadenosine = adenine + S-methyl-5-thio-alpha-D-ribose 1-phosphate</text>
            <dbReference type="Rhea" id="RHEA:11852"/>
            <dbReference type="ChEBI" id="CHEBI:16708"/>
            <dbReference type="ChEBI" id="CHEBI:17509"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58533"/>
            <dbReference type="EC" id="2.4.2.28"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="3">
            <dbReference type="Rhea" id="RHEA:11853"/>
        </physiologicalReaction>
    </comment>
    <comment type="similarity">
        <text evidence="5 9">Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000020">
        <property type="protein sequence ID" value="PRC91641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91641">
        <property type="protein sequence ID" value="PRC91641"/>
        <property type="gene ID" value="S2091_3579"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004000">
        <property type="term" value="F:adenosine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017061">
        <property type="term" value="F:S-methyl-5-thioadenosine phosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd16833">
        <property type="entry name" value="YfiH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.140.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003730">
        <property type="entry name" value="Cu_polyphenol_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038371">
        <property type="entry name" value="Cu_polyphenol_OxRdtase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011324">
        <property type="entry name" value="Cytotoxic_necrot_fac-like_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30616">
        <property type="entry name" value="PTHR30616"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02578">
        <property type="entry name" value="Cu-oxidase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64438">
        <property type="entry name" value="SSF64438"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00726">
        <property type="entry name" value="TIGR00726"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00001600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00007353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC91641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="261" mass="27819" checksum="F926ABFFD6B46F21" modified="2018-07-18" version="1">MPPSCILKPDWPNLPSQIGALTTLRTGGVSCAPFDDGSGVDGFNLGTHVGDQIEHVLQNRSLLAQFLPDMPQWLSQVHGTTVLDLGSIVENAKSGLIADACFTTQANVVCAVQTADCLPVLFCDAKNGVVAAAHAGWRGLVDGVLENTLLKMQAAGAESKHILAWLGPAIGPLKFEVGAEVRARFMEVDPCASAAFKPGKEPGKFYADIYQLARMRLQCAGVVQISGGNFCTVSEPEKFYSYRRDGVTGRMASLIWIKGVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVA8</accession>
    <name>A0A2S9GVA8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="17">Fdh-alpha: formate dehydrogenase, alpha subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">S2091_3595</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>2Fe-2S cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49601"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mo-bis(molybdopterin guanine dinucleotide)</name>
            <dbReference type="ChEBI" id="CHEBI:60539"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">In the C-terminal section; belongs to the prokaryotic molybdopterin-containing oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000020">
        <property type="protein sequence ID" value="PRC91657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91657">
        <property type="protein sequence ID" value="PRC91657"/>
        <property type="gene ID" value="S2091_3595"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008863">
        <property type="term" value="F:formate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043546">
        <property type="term" value="F:molybdopterin cofactor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015942">
        <property type="term" value="P:formate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00207">
        <property type="entry name" value="fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02753">
        <property type="entry name" value="MopB_Formate-Dh-H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009010">
        <property type="entry name" value="Asp_de-COase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041924">
        <property type="entry name" value="Formate_Dh-H_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006478">
        <property type="entry name" value="Formate_DH_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006657">
        <property type="entry name" value="MoPterin_dinucl-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006656">
        <property type="entry name" value="Mopterin_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006963">
        <property type="entry name" value="Mopterin_OxRdtase_4Fe-4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019574">
        <property type="entry name" value="NADH_UbQ_OxRdtase_Gsu_4Fe4S-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00037">
        <property type="entry name" value="Fer4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04879">
        <property type="entry name" value="Molybdop_Fe4S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00384">
        <property type="entry name" value="Molybdopterin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01568">
        <property type="entry name" value="Molydop_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10588">
        <property type="entry name" value="NADH-G_4Fe-4S_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00926">
        <property type="entry name" value="Molybdop_Fe4S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00929">
        <property type="entry name" value="NADH-G_4Fe-4S_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50692">
        <property type="entry name" value="SSF50692"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="SSF54292"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01591">
        <property type="entry name" value="Fdh-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51839">
        <property type="entry name" value="4FE4S_HC3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51669">
        <property type="entry name" value="4FE4S_MOW_BIS_MGD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="6 12" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="10 12" id="KW-0408">Iron</keyword>
    <keyword evidence="11 12" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="8 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="13">
        <location>
            <begin position="18"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S His(Cys)3-ligated-type" evidence="16">
        <location>
            <begin position="96"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="14">
        <location>
            <begin position="158"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="14">
        <location>
            <begin position="202"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S Mo/W bis-MGD-type" evidence="15">
        <location>
            <begin position="237"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="244"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="247"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="251"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="279"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="PRC91657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="959" mass="105052" checksum="2B299E940408A851" modified="2018-07-18" version="1">MNQLNQIDFGTPERISETRVSIEIDGVEVTVAVGTSVMRAAAEAGVNVPKLCATDSLEAFGSCRLCLVEIEGRRGYPASCTTPCEPGMKVRTQTPKLAELRKGVMELYISDHPLDCLTCPTNGNCELQDMAGVVGLREVRYGYEGKNHLDLKKDESNPYFTYDASKCIVCNRCVRACEETQGTFALTIDGRGFDSRVSAGQNQPFMESECVSCGACVDACPTATLTEKTVIMMGQAEHSKITTCAYCGVGCSFKAEMKGNEVVRMVPNKDGHANHGHSCVKGRFAWGYATHKDRMLKPMIRKNITDPWNEVSWDEALAYAASEFRRIQAKFGKDSIGGITSSRCTNEETYLVQKLVRAAFGNNNVDTCARVCHSPTGFGLKQTLGESAGTQTFDSVMKSDVIMVIGANPTAAHPVFASQMKRRLRQGAKLIVIDPRTTELVKSPHIQADYHLKLRPGTNVAVITALAHVIISESLFDAEFVAERCDTQSFSDWKEFVLHADNSPEAVEAITGVSAADLRGAARLFAAGNNGAIYYGLGVTEHSQGSTMVMGIANLAMATGNVGREGVGVNPLRGQNNVQGSCDMGSFPHELPGYRHISDTTVRTQFEEAWQCILDPEPGLRIPNMFEAAIDGSFMGLYCEGEDIAQSDPNTQHVTAALSAMECIVVQDLFLNETAKYAHVFLPGSSFLEKDGTFTNAERRISRVRKVMPAKAGKSDWEVTVALSNALGYPMRYKHPSEIMDEIAALTPTFHGVSYKKIDELGSIQWPCNDAAPNGTPTMHIGEFVRGKGKFINTQFFATSEKITRKFPLILTTGRILSQYNVGAQTRRTENVQWHSEDVLEIHPHDAEDRGIKENNWVGIESRAGQTVLRAIITDRVQPGVVYTTFHFPESGANVITTDNSDWATNCPEYKVTAVQVMPVAQPSEWQKNYSRFNEEQLGLLNADANADDSSKKLSVVNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVB1</accession>
    <name>A0A2S9GVB1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">NADH:ubiquinone oxidoreductase 24 kD subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_3597</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>2Fe-2S cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49601"/>
        </cofactor>
        <text evidence="6">Binds 1 [2Fe-2S] cluster.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the complex I 24 kDa subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000020">
        <property type="protein sequence ID" value="PRC91659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91659">
        <property type="protein sequence ID" value="PRC91659"/>
        <property type="gene ID" value="S2091_3597"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1590">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002023">
        <property type="entry name" value="NuoE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041921">
        <property type="entry name" value="NuoE_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000216">
        <property type="entry name" value="NADH_DH_24kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01099">
        <property type="entry name" value="COMPLEX1_24K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="4 6" id="KW-0408">Iron</keyword>
    <keyword evidence="5 6" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0830">Ubiquinone</keyword>
    <feature type="binding site" evidence="6">
        <location>
            <position position="82"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="87"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="123"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="127"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000216-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC91659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="163" mass="17755" checksum="742BF4BBE89C769F" modified="2018-07-18" version="1">MDVASSFNIKDVEAIIKERRSLPGAMLPILHGIQEKIGYIPAEVVPLIALELNLSRAEVHGVISYYHFFRQKPAGRHVVQICRAEACQANGADALVQHAKATLACDFHETTSDGEFTLEPVYCLGQCACGPAMTIGEDLYARVSNDKFNRLLSTKLAAKRGAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVK7</accession>
    <name>A0A2S9GVK7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3512</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000019">
        <property type="protein sequence ID" value="PRC91757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91757">
        <property type="protein sequence ID" value="PRC91757"/>
        <property type="gene ID" value="S2091_3512"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12802">
        <property type="entry name" value="MarR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00598">
        <property type="entry name" value="HTHMARR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00347">
        <property type="entry name" value="HTH_MARR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50995">
        <property type="entry name" value="HTH_MARR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="1">
        <location>
            <begin position="24"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="162" mass="18631" checksum="8A3A9B13527E6655" modified="2018-07-18" version="1">MNVLPEPASEPAIDLETRLTDEHHLSLRLWLRMLSSTVKLETEIRSRLRIEFDITLPRFDLMAQLVRHPEGLRMGELSKRMMVTGGNITGIADQLEKEKLVERVVVANDRRSFSLKLTPEGLTSFKKMAIVHEQWVEELLHGLQAEEKHMLIQLLSKVKASL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVK8</accession>
    <name>A0A2S9GVK8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Collagen triple helix repeat (20 copies)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3496</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000019">
        <property type="protein sequence ID" value="PRC91741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91741">
        <property type="protein sequence ID" value="PRC91741"/>
        <property type="gene ID" value="S2091_3496"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008160">
        <property type="entry name" value="Collagen"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01391">
        <property type="entry name" value="Collagen"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0176">Collagen</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015739745" evidence="2">
        <location>
            <begin position="18"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="128" mass="11684" checksum="C73AAFF21B56536E" modified="2018-07-18" version="1">MKHSALLSLLVISLALGGCVTLPTGATGAAGPAGPQGSTGDTGNTGATGRVGNTGNTGNTGNTGATGYTGATGDTGATGNTGNTGATGYTGATGDTGATGNQGNRGATGNTGAKGTNSNGTVVIVPQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVR2</accession>
    <name>A0A2S9GVR2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glutathione S-transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3373</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000018">
        <property type="protein sequence ID" value="PRC91817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91817">
        <property type="protein sequence ID" value="PRC91817"/>
        <property type="gene ID" value="S2091_3373"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13409">
        <property type="entry name" value="GST_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="SSF47616"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GST N-terminal" evidence="1">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="2">
        <location>
            <begin position="86"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="207" mass="22961" checksum="7405A7DEB416497A" modified="2018-07-18" version="1">MLKILGKSSSINVRKVLWTCAEIGIPYDLEQWGAGAQATNTPYFLSLNPNGMVPVIQDGPATLWESNSICRYLAGKHQRVDLLPAEPLARAQVEKWMDWQATELNNAWRYAFMALVRRSAAHEDPAAITASVLAWNRHMAILDAQLANTGAYANGATFTLADIVLGLSVHRWMAAPIERPQLSAVDIYYARLSERDGFMQHGRNGLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVY2</accession>
    <name>A0A2S9GVY2_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Fumarate hydratase class II</fullName>
            <shortName evidence="2">Fumarase C</shortName>
            <ecNumber evidence="2">4.2.1.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Aerobic fumarase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="2">Iron-independent fumarase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">fumC</name>
        <name evidence="5" type="ORF">S2091_3438</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>(S)-malate = fumarate + H2O</text>
            <dbReference type="Rhea" id="RHEA:12460"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15589"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="EC" id="4.2.1.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate metabolism; tricarboxylic acid cycle; (S)-malate from fumarate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="2">There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.2" evidence="2"/>
    <dbReference type="EMBL" id="PUGF01000018">
        <property type="protein sequence ID" value="PRC91882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91882">
        <property type="protein sequence ID" value="PRC91882"/>
        <property type="gene ID" value="S2091_3438"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00223">
        <property type="reaction ID" value="UER01007"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045239">
        <property type="term" value="C:tricarboxylic acid cycle enzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004333">
        <property type="term" value="F:fumarate hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006106">
        <property type="term" value="P:fumarate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01362">
        <property type="entry name" value="Fumarase_classII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.275.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00743">
        <property type="entry name" value="FumaraseC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005677">
        <property type="entry name" value="Fum_hydII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024083">
        <property type="entry name" value="Fumarase/histidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018951">
        <property type="entry name" value="Fumarase_C_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020557">
        <property type="entry name" value="Fumarate_lyase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000362">
        <property type="entry name" value="Fumarate_lyase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022761">
        <property type="entry name" value="Fumarate_lyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008948">
        <property type="entry name" value="L-Aspartase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11444">
        <property type="entry name" value="PTHR11444"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10415">
        <property type="entry name" value="FumaraseC_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00206">
        <property type="entry name" value="Lyase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00149">
        <property type="entry name" value="FUMRATELYASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48557">
        <property type="entry name" value="SSF48557"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00979">
        <property type="entry name" value="fumC_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00163">
        <property type="entry name" value="FUMARATE_LYASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="Lyase_1" evidence="3">
        <location>
            <begin position="12"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="domain" description="FumaraseC_C" evidence="4">
        <location>
            <begin position="410"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="100"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding (B site)" evidence="2">
        <location>
            <begin position="131"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="141"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="326"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="2">
        <location>
            <position position="190"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="320"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="189"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="321"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="2">
        <location>
            <position position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF10415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC91882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="465" mass="49752" checksum="7E8252EF48B80CA5" modified="2018-07-18" version="1">MSTMRIESDSMGQIEVPADKYWGAQTQRSIDNFPIGVDRFKWQFPIIRAMGILKKSAALANGELGQLPEPLLAPIVQAADEVVTGLLNQHFPLVVFQTGSGTQSNMNANEVIANRAIEIMGGVLGSKVPVHPNDHVNCGQSSNDTFPTAMHIAVVSELLQTLFPKVTELRNTLAHKADLFNLVVKTGRTHLQDATPITLGQEIGSWVAQIDYSLATLETMMAGLYDLAIGGTAVGTGLNAHPRFGEVCAGHIAAITGFPFRSSSNKFFSLSAHDALVSTSAALRTLAGALLKIANDVRWLASGPRCGIGEIKIPENEPGSSIMPGKVNPTQCEALSMVCVQVFGNDAATAFAGSQGNFQLNVYKPVMVHNVLESIGLLGDACQAFNLHCAVGIEPDYAVIQRNLDNNLMLVTALNQHIGYDKAAKIAKAALHEGKTLREVALAMGLVSGVDFDLWMDPIKMTNVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVZ8</accession>
    <name>A0A2S9GVZ8_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Aspartokinase</fullName>
            <ecNumber evidence="13">2.7.2.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">S2091_3437</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>ATP + L-aspartate = 4-phospho-L-aspartate + ADP</text>
            <dbReference type="Rhea" id="RHEA:23776"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57535"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.2.4"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 14">Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; (S)-tetrahydrodipicolinate from L-aspartate: step 1/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 14">Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-homoserine from L-aspartate: step 1/3.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4 14">Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 1/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 13">Belongs to the aspartokinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.2.4" evidence="13"/>
    <dbReference type="EMBL" id="PUGF01000018">
        <property type="protein sequence ID" value="PRC91881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91881">
        <property type="protein sequence ID" value="PRC91881"/>
        <property type="gene ID" value="S2091_3437"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00034">
        <property type="reaction ID" value="UER00015"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00050">
        <property type="reaction ID" value="UER00461"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00051">
        <property type="reaction ID" value="UER00462"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004072">
        <property type="term" value="F:aspartate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009088">
        <property type="term" value="P:threonine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd04261">
        <property type="entry name" value="AAK_AKii-LysC-BS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036393">
        <property type="entry name" value="AceGlu_kinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041740">
        <property type="entry name" value="AKii-LysC-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001048">
        <property type="entry name" value="Asp/Glu/Uridylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005260">
        <property type="entry name" value="Asp_kin_monofn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001341">
        <property type="entry name" value="Asp_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018042">
        <property type="entry name" value="Aspartate_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027795">
        <property type="entry name" value="CASTOR_ACT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00696">
        <property type="entry name" value="AA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01842">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13840">
        <property type="entry name" value="ACT_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000726">
        <property type="entry name" value="Asp_kin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53633">
        <property type="entry name" value="SSF53633"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00657">
        <property type="entry name" value="asp_kinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00324">
        <property type="entry name" value="ASPARTOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 14" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="10 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 13 16" id="KW-0418">Kinase</keyword>
    <keyword evidence="11" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="8 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ACT" evidence="15">
        <location>
            <begin position="274"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="domain" description="ACT" evidence="15">
        <location>
            <begin position="356"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="7"/>
            <end position="10"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="47"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="74"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="173"/>
            <end position="174"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="179"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="184"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="209"/>
            <end position="210"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR000726-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU003448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU004249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="PRC91881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="417" mass="44945" checksum="9B5382C924190AB0" modified="2018-07-18" version="1">MALIVQKYGGTSMGSTERIKNVAKRVAKWHDAGYQIVVVPSAMSGETNRILGLAKEICEHPDPRELDVIASTGEQVSVGLLAIALQAIGKQAVSYAGWQVAIKTDASHAKARIASIDDAKVQRDLDAGKIVIITGFQGVNEQGDITTLGRGGSDTSAVAVAAALKAQECMIFTDVDGVYTTDPRVVTEARRLRTVTFEEMLEMASLGSKVLQIRSVEFAGNYKMPTRVLSSLTDPLIPLEIEAKSGTLISFEEDTHMEQATITGIAFNRDEAKITVFGVPDRPGIAYQILGPVADANIEVDMIIQNQSVEGKTDFTFTVPRNEYTNAMEVLVKTGVQNHISATGIIGDAKVSKVSVVGVGMRSHVGIASQMFRTLSEEGINIQMISTSEIKISVLIDEKYMELAVRALHKTFGLENS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GW47</accession>
    <name>A0A2S9GW47_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3284</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000017">
        <property type="protein sequence ID" value="PRC91942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91942">
        <property type="protein sequence ID" value="PRC91942"/>
        <property type="gene ID" value="S2091_3284"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="66" mass="7358" checksum="E69C03D6991561DA" modified="2018-07-18" version="1">MKNKPLHSSEKLVHLDAILDEALTESFPASDPIAVSFPRAVDLASNEPIEIAKEVQKRKKSSKHKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GW51</accession>
    <name>A0A2S9GW51_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glyoxalase-like domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3286</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000017">
        <property type="protein sequence ID" value="PRC91944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91944">
        <property type="protein sequence ID" value="PRC91944"/>
        <property type="gene ID" value="S2091_3286"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004360">
        <property type="entry name" value="Glyas_Fos-R_dOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00903">
        <property type="entry name" value="Glyoxalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="2"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="129" mass="14457" checksum="C0CB5CB0561D4BCC" modified="2018-07-18" version="1">MKRTWTIIGVADVASSFRWYQSLFGQTETKPAHDYFGQIIDTDGTVLLCLHQWGSHDHPPLTSPDHVQPGNGLLLFFRVDDFNETLLRARALVVGLEEEPHLNPNTGTSEFALRDLDGYYVMISALAAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWA7</accession>
    <name>A0A2S9GWA7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3345</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000017">
        <property type="protein sequence ID" value="PRC92003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92003">
        <property type="protein sequence ID" value="PRC92003"/>
        <property type="gene ID" value="S2091_3345"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07377">
        <property type="entry name" value="WHTH_GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00392">
        <property type="entry name" value="GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50949">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="1">
        <location>
            <begin position="9"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="122" mass="13745" checksum="650E7E13A74117C3" modified="2018-07-18" version="1">MTIGWNDNAPIYRQLKERVIGMMLDGVIKSGDALPSVRQIAAEYQLNPITVSRAYQELVDETLVEKRRGLGMYVIDGARDKLLASERERFIREEWPALLERIGRLGLDLNQLMQSSKVGGAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWJ3</accession>
    <name>A0A2S9GWJ3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3196</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000016">
        <property type="protein sequence ID" value="PRC92061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92061">
        <property type="protein sequence ID" value="PRC92061"/>
        <property type="gene ID" value="S2091_3196"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021267">
        <property type="entry name" value="DUF2844"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11005">
        <property type="entry name" value="DUF2844"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="135" mass="14598" checksum="63EF4F2CFA1F532A" modified="2018-07-18" version="1">MVCAAPSFAELGGTVAKEAVQIKEQSSIVATDQTLNVYQVKMPSGTQIKEYANADGVVVAVTWQGPTLPNLKVLLGDHFDEFANRKPSSLAINRRSAAIHTDDLVVQSHGQMRSFAGFAYLPKLLPPGFNLDQIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWK7</accession>
    <name>A0A2S9GWK7_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA helicase</fullName>
            <ecNumber evidence="2">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_3235</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O = ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="2"/>
    <dbReference type="EMBL" id="PUGF01000016">
        <property type="protein sequence ID" value="PRC92100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92100">
        <property type="protein sequence ID" value="PRC92100"/>
        <property type="gene ID" value="S2091_3235"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014017">
        <property type="entry name" value="DNA_helicase_UvrD-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000212">
        <property type="entry name" value="DNA_helicase_UvrD/REP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014016">
        <property type="entry name" value="UvrD-like_ATP-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11070">
        <property type="entry name" value="PTHR11070"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00580">
        <property type="entry name" value="UvrD-helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13361">
        <property type="entry name" value="UvrD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51198">
        <property type="entry name" value="UVRD_HELICASE_ATP_BIND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51217">
        <property type="entry name" value="UVRD_HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 8" id="KW-0347">Helicase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UvrD-like helicase ATP-binding" evidence="6">
        <location>
            <begin position="15"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="domain" description="UvrD-like helicase C-terminal" evidence="7">
        <location>
            <begin position="519"/>
            <end position="797"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="36"/>
            <end position="43"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC92100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="1096" mass="122015" checksum="AB4FDC4C61889243" modified="2018-07-18" version="1">MEENIISAYQVNSQNSSASQFISAACDPRNSVVVEACAGSGKTWLLVARMLRLLLAGAEPAELLAITFTRKAAQEMRQRLLDLLQELALADDAKVSALLLERGISESQLGELIPKARGMYEHVLSSRQALALDTFHSWFGRLIQIAPLNSGVPHGFTLTEATSELRNEAYRQLMNSLKSEKNAHIKQALISLYEELGDFNAKKILDAFLDKRAEWWACNEDAEQGSPLEWLQELCGLDATVDARLTLWGDSAWLERISQIARWLGFGTATNQKRAVAIETAISNGASVENFFALCHEFFGADDKNRSNLKTKALQAALEKDLGADCAAVFDDECSLIADQLRLRQQRSLEKLVIQINQALFVVGEAYLDFYQSLKAEQRVFDFSDLEWQAYRLLKSEQHAAYVQNRLDSRYKHILLDEFQDTNPLQWSIVRAWLDAYGADSERPSVFIVGDPKQSIYRFRRADPRVFAAASAMLQAQGAYVLRTNQTRRNGTMIVDVLNACMTQNPLFTAQSTLEKTVGEVWRLPLVIVTDDTGQNGEIAGLRNPLTTPIQEAEDSRRLEEGRMVAQALLVARNDAADLGVPLLWSEVMLLVRRRTHLSAYETALREVGIPFVSSRRGGLLDALEVADVIALLRFLITPSDNQALAHVLKSPIISASDDDLIALAQRTEPTWWKRLLATNSDNLILNRAKQLLQDWMDAAHFLPVHDLLDRILHQGELVQRYAQHAAYAGRNQVIGNLAAFTELALNMDAGRYPSLPKFIAALSEVQLGDEGDSPDESNVESNADAVRILTIHSAKGLEAKVVVILDANHSEGAKDSLGILCEWPLDEGSQQKHFSAFGRKNQRGAARDVLFNQEQQLAEQENWNLLYVAATRAKQCLIISGVAGAKTAIAANSWYERLQEVDEFMAIQTASAELGAQATQFELTSFVAPDLALPFIDNVHSDAGSEAQLEGIALHSLMERLTGPGAPWPIVFPDTATIAQWLACSAGLAQIIREQAQAILQKSELERFFNPAQFRFARNEMEIISDNKVHRLDRVVVFDDAVWVLDFKRQLLTMERAAYQAQLEEYCALLSQIYRQEKICAGLILADGSLVELLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWL2</accession>
    <name>A0A2S9GWL2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Bacterial extracellular solute-binding protein, family 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_3223</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000016">
        <property type="protein sequence ID" value="PRC92088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92088">
        <property type="protein sequence ID" value="PRC92088"/>
        <property type="gene ID" value="S2091_3223"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001638">
        <property type="entry name" value="Solute-binding_3/MltF_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00497">
        <property type="entry name" value="SBP_bac_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015746177" evidence="2">
        <location>
            <begin position="23"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="domain" description="PBPb" evidence="3">
        <location>
            <begin position="104"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC92088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="242" mass="27509" checksum="4EBDCB7B7BBD4E34" modified="2018-07-18" version="1">MRRRTLFKLAALPFLATLPGLAQEKTSLQISTLLEQDPATSIAEQVMAEAYRRLNIKMKLTRLPGERSLQSANDGEVDGELYRKLYMEKDYPNLLIVPVELLKYEIVIFTRSTKFVVNGWESLRPYTLGFVKSIKIIEQNTAGMKIEVAATLRQAFLKMMLARSDVVIANRLSGLAVLKELNLPEITILEPPLATFPVFHYLNKKHAALIPQLTKVLVQMQKDKTILNLQKAVMLEHGLQEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWM8</accession>
    <name>A0A2S9GWM8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3201</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000016">
        <property type="protein sequence ID" value="PRC92066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92066">
        <property type="protein sequence ID" value="PRC92066"/>
        <property type="gene ID" value="S2091_3201"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="204" mass="22693" checksum="160751D8D89673A3" modified="2018-07-18" version="1">MHIASKINSPTTLFKADYSAPLLNSTMTLMLTKTLKHHLSAQLDDEFINFLDDEEDEIDLRDIKPWQILVTDDDQTVHDSTVLALNGVMIQGRPLEFLHAFSAREGRDVLLANPETAVILLDVVMETIDAGLCLVDTIRGELQRQDLRIVIRSGQPGGVHTSHESYRSSVDAFTIKSKITRSGLIDVLEEVLIIPPPASHQISD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWR7</accession>
    <name>A0A2S9GWR7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3078</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92162">
        <property type="protein sequence ID" value="PRC92162"/>
        <property type="gene ID" value="S2091_3078"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021267">
        <property type="entry name" value="DUF2844"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11005">
        <property type="entry name" value="DUF2844"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="200" mass="21612" checksum="2D5D2735A03DDC04" modified="2018-07-18" version="1">MSVRPVVAINDLKGHIFYLENKWGVSIVSNRITAKAENKVISLLPKAAISLAMLAISFSAHATLGEQAASVTADQSALHATMTATVGTSYTDYALTLPKGLVVHELVNPAGRVFEVTWSGRGQRPDMAQLLGTYVTRFTRQTQAGQVTGKPTDRHMDRVESDLVIHSAVRNRFFSGTAHIPGMIPDTMSGPVKVNVEVNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GX37</accession>
    <name>A0A2S9GX37_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">MerR HTH family regulatory protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2942</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92283">
        <property type="protein sequence ID" value="PRC92283"/>
        <property type="gene ID" value="S2091_2942"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000551">
        <property type="entry name" value="MerR-type_HTH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13411">
        <property type="entry name" value="MerR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00422">
        <property type="entry name" value="HTH_MERR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50937">
        <property type="entry name" value="HTH_MERR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH merR-type" evidence="1">
        <location>
            <begin position="21"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="129" mass="14968" checksum="D2AA579F908C9F08" modified="2018-07-18" version="1">MSETLHKDDALVLPAIPAKRYFTIGEVSDLCGVKAHVLRYWEQEFSQLKPVKRRGNRRYYQHHEVLLIRRIRELLYEQGFTINGARNQLGGQSSLEINSPKETSELTFSGETAETLRTELLNIQKLLRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXD3</accession>
    <name>A0A2S9GXD3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">RHS repeat-associated core domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3041</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92382">
        <property type="protein sequence ID" value="PRC92382"/>
        <property type="gene ID" value="S2091_3041"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001826">
        <property type="entry name" value="RHS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022385">
        <property type="entry name" value="Rhs_assc_core"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00394">
        <property type="entry name" value="RHSPROTEIN"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03696">
        <property type="entry name" value="Rhs_assc_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="221" mass="23794" checksum="B76BA3BC9CAA0B97" modified="2018-07-18" version="1">MYGKSASGSSLDAETNLFYNYHRNYDPNSGRYIESDPIGLNGGISTYGYVKGKPNQYIDPFGEDATVTVNGNNVQVTIPITYTGNGATPALIASVNQSISSQWSGQFGNYIVTTSVVTGPGNTVNLVAGPGTSVVTDNNAGTWFTAGQGNFIWEVSHEAGHLMRLPDEYESTTCPDGKRKTTAKEGYAKNIMGAYGQTGITQQDISNIINANQSWYKRLFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXJ6</accession>
    <name>A0A2S9GXJ6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2817</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92442">
        <property type="protein sequence ID" value="PRC92442"/>
        <property type="gene ID" value="S2091_2817"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039536">
        <property type="entry name" value="TetR_C_Proteobacteria"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14246">
        <property type="entry name" value="TetR_C_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="14"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="37"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="209" mass="23901" checksum="7FC1AAA3004F5A4D" modified="2018-07-18" version="1">MSICLKPRWARRKDARPQELLSAALEIFVERGYAATRLEEVARKAGVSKGTLYLYFENKEELFKAVVRDTIVPNIAQAEQLISEFQGSTKELFIELITHWCEQISAPNLAGICKLMFAEASNFPELAEFYYAEVINRNELMIIQLLERGMQSGEFRQLDLSVMPKIVTAPIVMLMLWSNTFSCCEPHAIVRDDYVRSYIEVILAGLLKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXP1</accession>
    <name>A0A2S9GXP1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Membrane protease subunit stomatin/prohibitin-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_2858</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the band 7/mec-2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92483">
        <property type="protein sequence ID" value="PRC92483"/>
        <property type="gene ID" value="S2091_2858"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043202">
        <property type="entry name" value="Band-7_stomatin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001107">
        <property type="entry name" value="Band_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036013">
        <property type="entry name" value="Band_7/SPFH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001972">
        <property type="entry name" value="Stomatin_HflK_HflKC_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10264">
        <property type="entry name" value="PTHR10264"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01145">
        <property type="entry name" value="Band_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00721">
        <property type="entry name" value="STOMATIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00244">
        <property type="entry name" value="PHB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117892">
        <property type="entry name" value="SSF117892"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PHB" evidence="3">
        <location>
            <begin position="18"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="171"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC92483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="258" mass="29227" checksum="23928D064E7909AC" modified="2018-07-18" version="1">MNELSVFICLALFIFVMAGFRVANQYQRAVVFRLGKLQGLRGPGLYWIIPFFEWQKIIDIRTITISVDQQETITKDNVPVKVTVVIWYAVTDPIRSVVEVRDVDKSVIQVALTSMRNIIGRHTLDDVLKEQERLGADMRQTIDSATEPWGVKVTRVEMRNVEIPESMQRAMAQEAEALREKRARIIKAEAELEAAVKLRDAAKLIMENPAGLELRRMQMITEVGAEQNTTTIIMMPSEFVSMAKGIADFTAKLSNKDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXR8</accession>
    <name>A0A2S9GXR8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2875</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92500">
        <property type="protein sequence ID" value="PRC92500"/>
        <property type="gene ID" value="S2091_2875"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="298" mass="32491" checksum="9750E82D80C5673A" modified="2018-07-18" version="1">MSLILKAQQYVHMTLKVGALSSVAYRFTITASPSTFQFPSEVIPGTSFPTDMLFEGPPPATQVDINGEINNPQSLTCPAGWGPLGGKTVTPTTPSNSVQFAWLNGTTIVATAMDITYSDAISIAMNRPPLEAGAYGVKYFDGSTGVEVWDGNNWIGMANIARYSGRPFLLTKEEKKQCIENILAGINTPKQSDQRMIASGNALALARHYATKMEKNPTGHKVRIHILNMCGFYLLARNLGVSFTSNDNSTLASTTDKNLLAWAYQDIAKSDCDRIEAMLDGTLKRRADLQSWLKDKLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXV1</accession>
    <name>A0A2S9GXV1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">MoxR-like ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2598</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92543">
        <property type="protein sequence ID" value="PRC92543"/>
        <property type="gene ID" value="S2091_2598"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011703">
        <property type="entry name" value="ATPase_AAA-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041628">
        <property type="entry name" value="ChlI/MoxR_AAA_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07726">
        <property type="entry name" value="AAA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17863">
        <property type="entry name" value="AAA_lid_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_3" evidence="1">
        <location>
            <begin position="35"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="domain" description="AAA_lid_2" evidence="2">
        <location>
            <begin position="228"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="306" mass="33403" checksum="A2D4BBD9523D14B4" modified="2018-07-18" version="1">MFSKLHAAAEQLNQIIVGKPIQIRQALVCLLAGGHLLIEDIPGVGKTTLAHALAITLGLQMNRLQFTSDLMPADVIGISIFEREKNSFMFHPGPIFTQVLLADEINRATPKTQSALLEAMEERQVTAEGTTHALPQPFFVLATQNPLHQVGTFPLPESQLDRFLMCISLGYPDAAAERALLMGDDRRSMLQKLPKIMQAHELMAAQQAIKHIHCSASLLDYLQKLILETRRNGLFTAGLSPRAGLALLQAARAWAALEGRDHVIPEDVQAVFIAVAAHRLHPLASTSGNTMSSQALLSKLLKQVAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXW0</accession>
    <name>A0A2S9GXW0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Beta-lactamase class C and other penicillin binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2871</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92496">
        <property type="protein sequence ID" value="PRC92496"/>
        <property type="gene ID" value="S2091_2871"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015441699" evidence="1">
        <location>
            <begin position="33"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-lactamase" evidence="2">
        <location>
            <begin position="60"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="401" mass="43551" checksum="AE82C23D1774D79F" modified="2018-07-18" version="1">MIFSKIFSPKNLLIGIALAISSQFSVSGGVNAAELLHAANSLPPASIQTEASIKSIVTAAAQEYLSDPNTAGISIGIVRGNHNYAYHFGTVDKTLTQLPNDSTVYPIASITKTFTGTLLAQAELDHKLKITDDVRLYLNGDYPNLEFAKQPIQLFHLLNHRSGLPFILPNPPEAAPDFVDVVPYPLRIDKIVDSSNKNGFYTALHQITLSAAPGTHFQYSNAAAQLAGYIVEHVYGETFETLLHEKITGPLAMHDTVIELAPSQAKRLVIGYDENGARYQPSSNKFQGAAAIKSTLPDMLKYAQWQLDAHAPEVKLSHIPTYSNDDFSIGLNWQMLSANGRKVLWQDGATPGFASFCIPQPDANLALVILSNELGPATLGRLSAMANKIMKAIDERSITKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXX4</accession>
    <name>A0A2S9GXX4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2632</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92577">
        <property type="protein sequence ID" value="PRC92577"/>
        <property type="gene ID" value="S2091_2632"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="76" mass="9091" checksum="F060E612DAC23A43" modified="2018-07-18" version="1">MLEQTDVRHIKKPYRLFPAQQSSRQEQHRSKQSEHGIERNADESEWKCQQPDQRHENQRQNGDRPTQNKQNAPGNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXZ7</accession>
    <name>A0A2S9GXZ7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Dehydrogenases with different specificities (Related to short-chain alcohol dehydrogenases)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2644</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92589">
        <property type="protein sequence ID" value="PRC92589"/>
        <property type="gene ID" value="S2091_2644"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="256" mass="26158" checksum="2FEC7F199F6642AB" modified="2018-07-18" version="1">MNVLKNKVAIVTGASSGIGYATAKMFASEGANVVVTGRRKTELDRLVAQIVEAGGAAVAIVGDVKEESLAKRVVDAALHHFDGLDIAFNNAGIIGEMGPVHDLSLAAWRDTLDTNLTSAFLGAKYQIPAMIKRGGGSLIFTSSFVGYTVGLPGMTAYAASKAGLIGLTQVIAAEFGAQGIRANAVLPGGTDTPMSVTNAPGAGPEVLASIEALFALKRIAQPEEIARSVLHLASDASSFITGTAFLVDGGASITRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYB1</accession>
    <name>A0A2S9GYB1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2701</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92646">
        <property type="protein sequence ID" value="PRC92646"/>
        <property type="gene ID" value="S2091_2701"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="7"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="59"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="78" mass="8585" checksum="21AD8143B9844CCA" modified="2018-07-18" version="1">MKKSLRILKAFNLAALLLALFLIADFCSGWAGIALLILIFTLFFTSHAEGMADQYRKSVDDDLNPPGAPVTDFPELNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYJ8</accession>
    <name>A0A2S9GYJ8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2513</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92783">
        <property type="protein sequence ID" value="PRC92783"/>
        <property type="gene ID" value="S2091_2513"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036278">
        <property type="entry name" value="Sialidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50939">
        <property type="entry name" value="SSF50939"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="394" mass="42783" checksum="A5028C97BB06840A" modified="2018-07-18" version="1">MQIKLIKEDQKGTSFTPAQMSARHPWRVLSSMLLLCACISAPLTYAHPLTAQENAQWFKLPTEVYKGKQDDIFFIDPQTGFYGNGAGKIFKTTDGGQHWALVLNKPGTYVRALGFVDAQLGFAGNIGTEYFPGVTDTTPLYRTVDGGANWAPVTGMSGPEVKGLCAIDILKTSFINAGVLEHRTMVHAGGRVGGPAYLMRSLDGGSTWKSIDMNAHLASITDVKFFDEMNGMVVGGDDADIERSHAVVVSTRDGGETWQRAFTSSRMFELAWKVAFPSRNVGYVTVQDYNPDKTVTQRVVGKSVDGGKSWQEIPLADDFAVNEFGVGFADELTGWVGTSTSGFATTDGGKSWQRVNMGRAINKIRIVPDGEHYVGYAIGVEVFKFGTPPEGTHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYK7</accession>
    <name>A0A2S9GYK7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NADPH:quinone reductase and related Zn-dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2534</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92804">
        <property type="protein sequence ID" value="PRC92804"/>
        <property type="gene ID" value="S2091_2534"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PKS_ER" evidence="1">
        <location>
            <begin position="10"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="338" mass="35745" checksum="880C8604A3CF2505" modified="2018-07-18" version="1">MQAYQIKAGQQIAGLEVVQRTLSAPTGHEVQVRIHAVSLNYRDLMIVNGSYRVTSENPVIPCSDGAGEVIAVGAQVTRFKVGDRVAASFFPEWINGNPTTQNTAGALGAAVNGMLAEEVILSEDALVAIPKHLTYVEAATIPCAGVTAWNSLFVEGGLRAGDSVLLLGTGGVSIWALQLAKAAGLRTIITSSSDEKLERARSLGASATINYKTTPEWQDEVLRLTDGKGVDLVLEVGGQGTLPRSITSARMGGKVAIIGGVSGFGGEVNPAALIGSVKRLAGIFVGSRSMFEDLNKFLSVVEIHPVVDRIFPFLQAREAFTHLEKAAHFGKVVIEVRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYV5</accession>
    <name>A0A2S9GYV5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2310</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92893">
        <property type="protein sequence ID" value="PRC92893"/>
        <property type="gene ID" value="S2091_2310"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015500072" evidence="1">
        <location>
            <begin position="27"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="214" mass="23134" checksum="CA6E492AB41EC3A6" modified="2018-07-18" version="1">MSAVRIKLCSFFLTLVMFILSSGALATPVTENGLRLATQIDNLHVEQHWPAGVHVNWESGEPDGRHVGTSGKHTHCSAFVASAAKSLGIYILRPPEHSPILLANAQFDWLAAGETSTQGWRLAESGIEAQALANQGNLVVAVYKNRKNDKPGHIAIVRPDTKSDAEIMQDGPQITQAGLKNFQSTSLKVGFAGHPGAFINNKVRYYAHQVSFAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZB9</accession>
    <name>A0A2S9GZB9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Propionate catabolism operon regulatory protein PrpR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_2136</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93050">
        <property type="protein sequence ID" value="PRC93050"/>
        <property type="gene ID" value="S2091_2136"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000156">
        <property type="term" value="F:phosphorelay response regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019629">
        <property type="term" value="P:propionate catabolic process, 2-methylcitrate cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002197">
        <property type="entry name" value="HTH_Fis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012704">
        <property type="entry name" value="Sig_transdc_resp-reg_PrpR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010524">
        <property type="entry name" value="Sig_transdc_resp-reg_PrpR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002078">
        <property type="entry name" value="Sigma_54_int"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025944">
        <property type="entry name" value="Sigma_54_int_dom_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02954">
        <property type="entry name" value="HTH_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06506">
        <property type="entry name" value="PrpR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00158">
        <property type="entry name" value="Sigma54_activat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01590">
        <property type="entry name" value="HTHFIS"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02329">
        <property type="entry name" value="propionate_PrpR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00688">
        <property type="entry name" value="SIGMA54_INTERACT_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50045">
        <property type="entry name" value="SIGMA54_INTERACT_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma-54 factor interaction" evidence="6">
        <location>
            <begin position="221"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="481"/>
            <end position="502"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC93050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="538" mass="59502" checksum="ABC5514E367BB0DE" modified="2018-07-18" version="1">MRPTSPRSDQFDKPVIWTVSISRLFDLFRDIMLEYADDAHIEPIHLGFEDAVKVLRERMQTERCDAIIAAGSNAAYLKSRLPVPVIIAKASGFDVMQALARARKISAAIGIITYQQTMPELAEFKTTFGFDIAQRTYSTEEDARAQINELKADGIKAIVGAGLVSDLAEEAGLAGIFLYSSNSIRQAFNDALEIAKFSRLEAGPSLANRDTLRARHGVEALRGESELMQQVRQNITLFARSNASVLIQGATGSGKELAAQATHQASSRARAPFVAVNCGAIAESLLEAELFGYQDSAFTGARRGGHAGLIETAQRGTLFLDEIGEMPLTLQTRLLRVLEERQVVRVGATRPIPVDIRIISATHCDLLEKMELGQFRRDLYYRLAVLQLRLPTLSARLEDLLNLTEWCLKNALANLGVKPHANLSAEVIACRSLLESYDWPGNVRELRNVCERLALFLLAEPLQALTPRLLMLAMPELNTKLPPQLSHHSNHQQPEADAEPDLSRQNLTNILHSFKGNRAAAAAHLGISRTTLWRKMKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZE0</accession>
    <name>A0A2S9GZE0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2154</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93068">
        <property type="protein sequence ID" value="PRC93068"/>
        <property type="gene ID" value="S2091_2154"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="77"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="131" mass="14249" checksum="26085A6B3C99E12A" modified="2018-07-18" version="1">MESTIQNSPVLIYGEQGCGKTRHATALAKAFNKSTIVDEFIEGEGIELTEHDIAFTNVRPVNLPYIPFAFAMLSISQPQSSEQTTPPTALNTPPSLPLNQSEHSHLHTSKCTQDQASLNVTFSQPELPSAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZJ1</accession>
    <name>A0A2S9GZJ1_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">3-isopropylmalate dehydratase small subunit</fullName>
            <ecNumber evidence="10">4.2.1.33</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Alpha-IPM isomerase</fullName>
            <shortName evidence="10">IPMI</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Isopropylmalate isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">leuD</name>
        <name evidence="12" type="ORF">S2091_2238</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 10">Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>(2R,3S)-3-isopropylmalate = (2S)-2-isopropylmalate</text>
            <dbReference type="Rhea" id="RHEA:32287"/>
            <dbReference type="ChEBI" id="CHEBI:1178"/>
            <dbReference type="ChEBI" id="CHEBI:35121"/>
            <dbReference type="EC" id="4.2.1.33"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 10">Amino-acid biosynthesis; L-leucine biosynthesis; L-leucine from 3-methyl-2-oxobutanoate: step 2/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5 10">Heterodimer of LeuC and LeuD.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the LeuD family. LeuD type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.33" evidence="10"/>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93152">
        <property type="protein sequence ID" value="PRC93152"/>
        <property type="gene ID" value="S2091_2238"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00048">
        <property type="reaction ID" value="UER00071"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009316">
        <property type="term" value="C:3-isopropylmalate dehydratase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003861">
        <property type="term" value="F:3-isopropylmalate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009098">
        <property type="term" value="P:leucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01577">
        <property type="entry name" value="IPMI_Swivel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.19.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01031">
        <property type="entry name" value="LeuD_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004431">
        <property type="entry name" value="3-IsopropMal_deHydase_ssu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015928">
        <property type="entry name" value="Aconitase/3IPM_dehydase_swvl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000573">
        <property type="entry name" value="AconitaseA/IPMdHydase_ssu_swvl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033940">
        <property type="entry name" value="IPMI_Swivel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00694">
        <property type="entry name" value="Aconitase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00171">
        <property type="entry name" value="leuD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9 10" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="6 10" id="KW-0432">Leucine biosynthesis</keyword>
    <keyword evidence="8 10" id="KW-0456">Lyase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aconitase_C" evidence="11">
        <location>
            <begin position="1"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PRC93152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="215" mass="24382" checksum="F5D8BA61450C71B9" modified="2018-07-18" version="1">MDKFIVHKGIVAPLDRANVDTDAIIPKQFLKSIHRTGFGPNLFDEWRYLDHGEPGIDNSHRPLNPEFVLNQARYQGASILLTRKNFGCGSSREHAPWALQQFGFRAVIAPSYADIFYNNCFKNGLLPIVLPEATIDALFNETNAFIGFQLQIDLENQVISTASADRHFEFEIEAFRKHCLLNGLDDIALTLRSADKIREFEARHLASQPWLANTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZN8</accession>
    <name>A0A2S9GZN8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Superfamily II DNA and RNA helicase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">S2091_1929</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the DEAD box helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93191">
        <property type="protein sequence ID" value="PRC93191"/>
        <property type="gene ID" value="S2091_1929"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005580">
        <property type="entry name" value="DbpA/CsdA_RNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03880">
        <property type="entry name" value="DbpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 6 10" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Q_MOTIF" evidence="9">
        <location>
            <begin position="5"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="7">
        <location>
            <begin position="36"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="8">
        <location>
            <begin position="217"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="5">
        <location>
            <begin position="5"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC93191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="461" mass="50684" checksum="928B2ED7BE30674D" modified="2018-07-18" version="1">MQTDTSFQSLALSAPLLANLDSLGYTEMTPIQAASLPLILQQRDVIAQAKTGSGKTAAFSLGILAKLNPMYFAIQGLVICPTRELADQVANELRRLARAIDNVKVLTLCGGTAMRPQIVSLEHGAHIVVGTPGRLIDHISRETIKLSTVQTLVLDEADRMVDMGFYDDIVHIVNACSPRRQTLLFSATFPDDIRKASEQLMHEPAEVKVDSQHAANHIEQLFYLVQSEHRNAAVAQLLRHYRPVSTIAFCNTKIHCRELTEELQAQGISALALHGDLEQRDRDDVLVRFANQSCSVLVATDVAARGLDIQTLGAVINVDVCKDTEVHIHRIGRTGRAGEKGLALSLATPGEKKWVKLIEQYQGESVRWHELAELDTSNDSGLQAPMQSIFIMGGKKDKLRPGDLLGALTGDVGLNKEQVGKINVFEFVTYVALDRRIAAKALEKLSSSNIKGRLFKMRMID</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZQ5</accession>
    <name>A0A2S9GZQ5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">GABAtrnsam: 4-aminobutyrate transaminase</fullName>
            <ecNumber evidence="5">2.6.1.19</ecNumber>
            <ecNumber evidence="5">2.6.1.22</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_1949</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.19" evidence="5"/>
    <dbReference type="EC" id="2.6.1.22" evidence="5"/>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93211">
        <property type="protein sequence ID" value="PRC93211"/>
        <property type="gene ID" value="S2091_1949"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047298">
        <property type="term" value="F:(S)-3-amino-2-methylpropionate transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034386">
        <property type="term" value="F:4-aminobutyrate:2-oxoglutarate transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009448">
        <property type="term" value="P:gamma-aminobutyric acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00610">
        <property type="entry name" value="OAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004632">
        <property type="entry name" value="4NH2But_aminotransferase_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000521">
        <property type="entry name" value="Transaminase_4ab_Lys_Orn"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00700">
        <property type="entry name" value="GABAtrnsam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00600">
        <property type="entry name" value="AA_TRANSFER_CLASS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="3 4" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC93211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="426" mass="45588" checksum="12AF774B18FDD835" modified="2018-07-18" version="1">MNSNQEWKSRKDAATPRGVGVMCNFYAARAENSEIWDIEGKRYIDFASGIAVVNTGHRHPKIVAAIQQQLEHFTHTAYQIVPYGSYVELAEKINQLTPGKHAKKTAFFTTGAEAVENAIKIARSATKRPGVIAFSGAFHGRTSMGMALTGKVDPYKIGFGPFPGEVYHAPFPSELHGMSVEGALSALQTLFKTDIEPAKVAAIIIEPIQGEGGFCVTPVAFMQALRAICDQHGILLIADEIQTGFARTGKLFAMEHYGVIPDLMTIAKSLAGGMPLSGVCGKADIMDAPAPGGLGGTYAGNALAVAAALAVLDIIDDEKLIERANQLGQRLTNQLHTTMQDQGVKSRVAEVRGLGSMIAIEFKHPESGKPDADFTKKVQAYALDKGLLLLSCGVYGNVIRFLYPLTITDALMTEALGILDAALRAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZV3</accession>
    <name>A0A2S9GZV3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acetyltransferase (GNAT) family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1966</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93228">
        <property type="protein sequence ID" value="PRC93228"/>
        <property type="gene ID" value="S2091_1966"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="6"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="156" mass="17444" checksum="17113FE8D847E212" modified="2018-07-18" version="1">MRTTLSSVRLALASDAANLLTLMRELAVFEKYIAQFCVTEADLLERGLRADSARQFTAFLAEASNGQLLGYAVVYPVPFTFDLRPNLVLKELFVRETARGLGVGQALMTTVVAHAKQQGCARLKWDVMPTNTRAKTFYRRIGGVPDSAWENWIRQC</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0F4</accession>
    <name>A0A2S9H0F4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">PAS domain S-box protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_1852</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93465">
        <property type="protein sequence ID" value="PRC93465"/>
        <property type="gene ID" value="S2091_1852"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013655">
        <property type="entry name" value="PAS_fold_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011712">
        <property type="entry name" value="Sig_transdc_His_kin_sub3_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07730">
        <property type="entry name" value="HisKA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08447">
        <property type="entry name" value="PAS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="6"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="5">
        <location>
            <begin position="139"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="6">
        <location>
            <begin position="215"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="3">
        <location>
            <begin position="398"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC93465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="491" mass="54665" checksum="4CBF3E6C8C6D5CB7" modified="2018-07-18" version="1">MTAPIRVLIVEDDTVDRLACRRELTKSHLAEFVVLEATTGREGLQLAALHKPDCILLDYHLPDMNGIDFLSEMAGADQISTPIMLLTGAESAAVVAAAIKRGARDYLGKDIDGQYLKLLPTAIQRMLREQKLAEGKRQAEAKFRSLVEQIEAITYIVPLDGEGITSYISPQISKLGYSPEQWLADPELHARQIHPDDREMAMRSIENSRKGGHSLRQEYRLMMRNGETLWVRDEAKAVSDETGRYVFLQGILLDITQSKLAEHALRKSQEELRQLAGHLERIKEEERKRIAQEIHDELGGLLAGIKAYVSVYIEREARSGRPPEPLLVDAVALADTGFQAVRRVITDLRPSVLDQLGVWAALEWYASQIEKRSKLQCTCIIEDDAAAIEPDSETSTMLFRVVQEALTNVVRHAEATTVSIHVALDDAMLVISVQDNGNGIDSARQLTRESWGITGMGERARYFGGEVTITGKIGEGTCVKLHLPLEKLNSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0L1</accession>
    <name>A0A2S9H0L1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1880</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93493">
        <property type="protein sequence ID" value="PRC93493"/>
        <property type="gene ID" value="S2091_1880"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="8"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="301" mass="33568" checksum="02E39F45359A7166" modified="2018-07-18" version="1">MKTPIENISWDDLRFFLHVGRGGSLTAAALSMSVSHATAFRRLQRLERDIGVQLFSKTRSGYKLTEAGDDLMRVIADLDLEVQTAMRRLSSRDAWPGGLVRVTTTDTLMHQILPSILTSFQRSSGVQLHINTSSALLDLIKGEADVAIRAGGRPPEPLVGRRVCRIESTVYYSKKMRNVSIKNMNAFPWVAGDDSFAHLDSSKWLRAQGLDNATVIRTSSYVNVLNVIKDGAGLGVLSCYMGDLEPSLCRLMPPPKEWRSDLWLLTRAELRNVPRIKKLFDAVYDGTRSMVPLFEGQAPMM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0N6</accession>
    <name>A0A2S9H0N6_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Phosphoribosyl pyrophosphate synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_1897</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the ribose-phosphate pyrophosphokinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93510">
        <property type="protein sequence ID" value="PRC93510"/>
        <property type="gene ID" value="S2091_1897"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004749">
        <property type="term" value="F:ribose phosphate diphosphokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009165">
        <property type="term" value="P:nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029099">
        <property type="entry name" value="Pribosyltran_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRibTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005946">
        <property type="entry name" value="Rib-P_diPkinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10210">
        <property type="entry name" value="PTHR10210"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00156">
        <property type="entry name" value="Pribosyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13793">
        <property type="entry name" value="Pribosyltran_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01251">
        <property type="entry name" value="ribP_PPkin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="1 3" id="KW-0545">Nucleotide biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pribosyltran_N" evidence="5">
        <location>
            <begin position="5"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="Pribosyltran" evidence="4">
        <location>
            <begin position="144"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00029942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF13793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC93510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="306" mass="33597" checksum="7F772C7BC90263F4" modified="2018-07-18" version="1">MRPLLFTLPGSEEFGAQLHPFLFCDIGDLQIHHFPDQECCPRFVTPVVGRDVIFAQLLDRPESKIMPLYLAACVARELGARSVGIVIPYLPYMRQDARFKEGEGETARHFARLISSCCDRLVTVDPHLHRYHQLSELYTVPTKVAFAAPEIAKWIIGNVIRPVIFGPDAESEQWIAEIAEAADCPYVVLNKTRHSSDSNVEVSIPDASFWVGMTPVLIDDIVSTARTMIAATLQIELAGMAPPVCIAVYPLFAGNAFAALQACGVDRIVSCNTIAHATNQINLCQPIAAAVDEALELMRVIPSTAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0N8</accession>
    <name>A0A2S9H0N8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NADH(P)-binding</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1542</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93541">
        <property type="protein sequence ID" value="PRC93541"/>
        <property type="gene ID" value="S2091_1542"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="1">
        <location>
            <begin position="91"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="298" mass="33793" checksum="1FCC970643F3B400" modified="2018-07-18" version="1">MSEIENNKFQAIGVLGATSFVGVSVLQQLEIADRSVFAFSRRTVTQFTGGIKWLQIEADSMQQNAAENKIPLWICLAPIAVLPEYFTLLEAHCVRRVVALSSTSRFTKDNSSDRNERILSKQLADAEARLQIWAESRCVEWVILRPTLIYGFGRDKNISEIANFIRRFGFFPLLGKASGLRQPIHAQDVAEACFDALCASSSANHAYNISGDEVLTYREMVSRICFALDKRPRMLSIPLWMFSMTVTVLRILPRYRKWSGAMAERMNCDMVFDHLEAKQDFGFNPRKFALTSTDIPKC</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H134</accession>
    <name>A0A2S9H134_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Thioredoxin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_1692</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SCO1/2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93691">
        <property type="protein sequence ID" value="PRC93691"/>
        <property type="gene ID" value="S2091_1692"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02968">
        <property type="entry name" value="SCO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003782">
        <property type="entry name" value="SCO1/SenC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12151">
        <property type="entry name" value="PTHR12151"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02630">
        <property type="entry name" value="SCO1-SenC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0186">Copper</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015764880" description="Thioredoxin domain-containing protein" evidence="3">
        <location>
            <begin position="22"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="4">
        <location>
            <begin position="30"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010996"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC93691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="193" mass="21392" checksum="F40DD66A2010BA3B" modified="2018-07-18" version="1">MKKLIILFGLLLSLGACSQNAKPDFKNTDVTGLAYANDFSLPDFNGKMRHLSDFKGKVVVMFFGYTQCPDVCPTTMAELSTVMQELGPLSDQVQVLFVSLDPERDTKKILSQYVPAFDKRFLGLVGDASATKKIADDFKIFYEKVPGKTPGSYTIDHSAGSYVFDKEGHIRLFARFNQGPAPIAHDLKLLLNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1Q5</accession>
    <name>A0A2S9H1Q5_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Flagellar biosynthetic protein FliQ</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">fliQ</name>
        <name evidence="10" type="ORF">S2091_1507</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Role in flagellar biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="9">Bacterial flagellum basal body</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the FliQ/MopD/SpaQ family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93898">
        <property type="protein sequence ID" value="PRC93898"/>
        <property type="gene ID" value="S2091_1507"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009425">
        <property type="term" value="C:bacterial-type flagellum basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044780">
        <property type="term" value="P:bacterial-type flagellum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002191">
        <property type="entry name" value="Bac_export_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006305">
        <property type="entry name" value="FliQ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34040">
        <property type="entry name" value="PTHR34040"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01313">
        <property type="entry name" value="Bac_export_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004669">
        <property type="entry name" value="FliQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00952">
        <property type="entry name" value="TYPE3IMQPROT"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01402">
        <property type="entry name" value="fliQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0975">Bacterial flagellum</keyword>
    <keyword evidence="4 9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10" id="KW-0966">Cell projection</keyword>
    <keyword evidence="10" id="KW-0969">Cilium</keyword>
    <keyword evidence="10" id="KW-0282">Flagellum</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="13"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="51"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU364090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC93898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="88" mass="9585" checksum="785BFB3F8AB44936" modified="2018-07-18" version="1">MNSDVVLQLSSQLLWNAILISAPILGLTLLVGLTVSILQVVTQVQDMSLTFIPKVLSAVVALTVFGPWMLHKLLSYATNLISNIPSYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1X2</accession>
    <name>A0A2S9H1X2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative Helix-turn-helix domain of transposase IS66</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_1158</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC93985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93985">
        <property type="protein sequence ID" value="PRC93985"/>
        <property type="gene ID" value="S2091_1158"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004291">
        <property type="entry name" value="Transposase_IS66_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024463">
        <property type="entry name" value="Transposase_TnpC_homeodom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024474">
        <property type="entry name" value="Znf_dom_IS66"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03050">
        <property type="entry name" value="DDE_Tnp_IS66"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13007">
        <property type="entry name" value="LZ_Tnp_IS66"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13005">
        <property type="entry name" value="zf-IS66"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LZ_Tnp_IS66" evidence="3">
        <location>
            <begin position="50"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="domain" description="zf-IS66" evidence="2">
        <location>
            <begin position="114"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="domain" description="DDE_Tnp_IS66" evidence="1">
        <location>
            <begin position="172"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC93985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="214" mass="24162" checksum="157226A6D1E1D387" modified="2018-07-18" version="1">MLTTSPDSLPNDTDALKALLLQRDQELEQLRATVSTLQQALSIRSLEIEQLQLQINKLKRMQFGRKSEKLDRQIAQLETRLEDLIAEEGQEHYQSKALPTELPRIEHRHEPESCSCGACGQALVQIGEDITEQLDVDPARFFVQRHIRPQYACRHCETITAAAIPAAIIDGGLATPSLHAWVVIQKYLDHLPLYRIEQISTRHGVAISRSTLAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H255</accession>
    <name>A0A2S9H255_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1196</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94023">
        <property type="protein sequence ID" value="PRC94023"/>
        <property type="gene ID" value="S2091_1196"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021457">
        <property type="entry name" value="DUF3108"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11306">
        <property type="entry name" value="DUF3108"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="52"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="349" mass="38101" checksum="C4CBBAD478F33FD8" modified="2018-07-18" version="1">MNTRRIIPIFLTALAHLVLLQFFSGTRFTSPIPNIVVPVTLHEIPVITKFTAPPPKATPQKKIQPLPPHPKAPVEIEPISQSPEPAESTESAAPMAEPAATELSVAAPIPETIPAPVAQTAPALSTLPPPSASYILDVVRTEPNVANPYYGSGEIRWEHDDKSYTMQMEVGVNLLFTTIRLYSLQSEGELAETGIKPRTVTETRRGRSATATHFNYDSNTISFSASTAMLPLSDGAQDKATVLMQLASIGNADPSQFQAGKNITIQVAEEKEASPYQFVVVEQETIDTKLGHLLTWHIVRPPRPGLYSSRLDIWIAPDLHWLPVQIRNSEANGAITTQTIRKIITGSKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H267</accession>
    <name>A0A2S9H267_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GlcNAc-PI de-N-acetylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1129</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC93956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93956">
        <property type="protein sequence ID" value="PRC93956"/>
        <property type="gene ID" value="S2091_1129"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10320">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003737">
        <property type="entry name" value="GlcNAc_PI_deacetylase-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024078">
        <property type="entry name" value="LmbE-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02585">
        <property type="entry name" value="PIG-L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102588">
        <property type="entry name" value="SSF102588"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="195"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="264" mass="30743" checksum="3F8C9027F37D977A" modified="2018-07-18" version="1">MKITTSTPVALFLFAHQDDEFGVFHAILSEVNQGHRIICAYLTNGHAKNVTSEIRNQESISVLLKLGVKKQDIFFPGDTLNISDSKLLEHLERASNWLKEILSEVSNLAAIYIPAWEGGHQDHDALHALTVCTTMNSDVFNRVRQFPLYNRYLCIGSFFRVLSPLPSNGVVEKINIPLKNRIDFLRYCLSYPSQLVTWIGLFPFVFLHYVFIGKQQLQHVSYERIFQRPHSGFLYYEKRRFFTWEQMENCLLKWIDINNKNKLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H284</accession>
    <name>A0A2S9H284_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1262</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94089">
        <property type="protein sequence ID" value="PRC94089"/>
        <property type="gene ID" value="S2091_1262"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="37" mass="4322" checksum="C9C411E76A8FEBAB" modified="2018-07-18" version="1">MLIIIEFSIFAIALSLGYLIRRIELSVPNCNEDFIFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2J2</accession>
    <name>A0A2S9H2J2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Phenylalanine-4-hydroxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_0823</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94202">
        <property type="protein sequence ID" value="PRC94202"/>
        <property type="gene ID" value="S2091_0823"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004505">
        <property type="term" value="F:phenylalanine 4-monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006559">
        <property type="term" value="P:L-phenylalanine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03348">
        <property type="entry name" value="pro_PheOH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.800.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001273">
        <property type="entry name" value="ArAA_hydroxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036951">
        <property type="entry name" value="ArAA_hydroxylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036329">
        <property type="entry name" value="Aro-AA_hydroxylase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019774">
        <property type="entry name" value="Aromatic-AA_hydroxylase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005960">
        <property type="entry name" value="Phe-4-hydroxylase_mono"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11473">
        <property type="entry name" value="PTHR11473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00351">
        <property type="entry name" value="Biopterin_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00372">
        <property type="entry name" value="FYWHYDRXLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56534">
        <property type="entry name" value="SSF56534"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01267">
        <property type="entry name" value="Phe4hydrox_mono"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51410">
        <property type="entry name" value="BH4_AAA_HYDROXYL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-0585">Phenylalanine catabolism</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BH4_AAA_HYDROXYL_2" evidence="8">
        <location>
            <begin position="1"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009712"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51410"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC94202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="290" mass="32949" checksum="1B88A6C1C8FB7A41" modified="2018-07-18" version="1">MQDSKLDFFATVAEKSDGASLRGDYADISEDYVVKQNWAAYTAEEHALWRKLYQRQAALLPGRACDEFIVSLNALHATDGIPNLEATSKALFEATGWSIVAVPGLIPELAFFTHLANRRFPITVWLRKPEEFDYIVEPDIFHDYFGHVPLLFNPIFADHIQEYGKGGLKAMQLGGLDQLARLYWYTIEFGLIQSPEGLRVYGAGILSSGGELTYSLEPSSSRHIALDVERCMRTLYKIDSYQETYFVIRDFKQLFEDTAPDFTPMYQRIKQQEPLPANSLLDGEIELLNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2L4</accession>
    <name>A0A2S9H2L4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1279</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94106">
        <property type="protein sequence ID" value="PRC94106"/>
        <property type="gene ID" value="S2091_1279"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="SSF48264"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0349">Heme</keyword>
    <keyword evidence="1" id="KW-0408">Iron</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="483" mass="54416" checksum="EC454FA7FEC61035" modified="2018-07-18" version="1">METNEVATQSEFASTNLRQLADLPAPKGLPFLGNALQIKGHRLHQQFEQWSREYGSYFRVKIGARKLLIVADHQAFAKILRDRPDGFSRTVKLAETWREMGLQVGLFGANGEVWKRQRRMVMAGFDPAHVKAYFPAMCKVTDRLESRWKKSIGTEIDLQADLMRFTVDTITGLAFGHDVNTLESGDDVIQRHLDKIFPAVFKRNLAVFKYWKYFRLPSDRELERSVAEVNVAIEGFVKQARERIKQVPTLRENPTNLLEAMINAADLGDSGLNDTDVAGNVLTMLLAGEDTTANSIAWLLELLWKNPAALQQLQEEVRGKFALDTPYSTENLNELDYLDACINEAMRLKPVAPLLPLQATKDTVIGDIHIPTGTIVFGLFRRDSVDDNFIPNAAQFDPQRWLSNGETGQAINSVKRISMPFGAGPRICPGRYLALLEMKIAMVMLLTRFDIDNISTPNGQDAEEHLAFTMAPLGLKMRLKLRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2L9</accession>
    <name>A0A2S9H2L9_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 4">Cell division topological specificity factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">minE</name>
        <name evidence="5" type="ORF">S2091_0850</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 4">Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the MinE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94229">
        <property type="protein sequence ID" value="PRC94229"/>
        <property type="gene ID" value="S2091_0850"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032955">
        <property type="term" value="P:regulation of division septum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1070.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00262">
        <property type="entry name" value="MinE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005527">
        <property type="entry name" value="MinE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036707">
        <property type="entry name" value="MinE_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03776">
        <property type="entry name" value="MinE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55229">
        <property type="entry name" value="SSF55229"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01215">
        <property type="entry name" value="minE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4 5" id="KW-0132">Cell division</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00020112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00025265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC94229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="88" mass="9781" checksum="F5E79F0E5BBF59C1" modified="2018-07-18" version="1">MALLSFLFNTAKPKTASAAKERLQIIIARERSGRSGYDFLPALHAELIAVISKYTKVDPKDITLSLDRKGDLEVLDVNVVLPEIELRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2N9</accession>
    <name>A0A2S9H2N9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0876</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94255">
        <property type="protein sequence ID" value="PRC94255"/>
        <property type="gene ID" value="S2091_0876"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027396">
        <property type="entry name" value="DsrEFH-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003787">
        <property type="entry name" value="Sulphur_relay_DsrE/F-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02635">
        <property type="entry name" value="DrsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75169">
        <property type="entry name" value="SSF75169"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015573191" evidence="1">
        <location>
            <begin position="25"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="141" mass="14926" checksum="0C41D16372434ECC" modified="2018-07-18" version="1">MKIIRILQSFFIALALISSTTAWASGATVVYHIDDSANARMVLGNVTNHLIAAPDTKIHVVSNGKGIEFLLVDAQDSNGKPYAPAIQALAAKGVAFKVCRNSLNSRKLGDNAVIAEATIVPAAVAEIARLEIDEKAAYIKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2U2</accession>
    <name>A0A2S9H2U2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0926</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94305">
        <property type="protein sequence ID" value="PRC94305"/>
        <property type="gene ID" value="S2091_0926"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="132" mass="15437" checksum="FAF78D59311AB7F7" modified="2018-07-18" version="1">MSGEERRIQRVAARWIITAITAMSAHCRQIGLLKPVIQAARFEYKRKVSYPIETPGWHKCRMKNVVEILPNASTVNMPLWLVVHRKIKGNPIIGNVFNQLSKILIEEISVDQRHFCQLYFNYIHRPPFFLPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2U6</accession>
    <name>A0A2S9H2U6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1359</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94186">
        <property type="protein sequence ID" value="PRC94186"/>
        <property type="gene ID" value="S2091_1359"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015504026" evidence="1">
        <location>
            <begin position="20"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="105" mass="11738" checksum="4A1514D1CE1BFC9C" modified="2018-07-18" version="1">MKLLFPFILAALFSTQVLADEPAMHNCKQPPVPGKFASATQLKEIDKNTRTYKACMMKFADEQQEISKNATEVAAANKAHDAAEAAIKEFNDYMKLRNDRESGEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2V6</accession>
    <name>A0A2S9H2V6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glutathione S-transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0817</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94196">
        <property type="protein sequence ID" value="PRC94196"/>
        <property type="gene ID" value="S2091_0817"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13417">
        <property type="entry name" value="GST_N_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="SSF47616"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GST N-terminal" evidence="1">
        <location>
            <begin position="28"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="239" mass="27042" checksum="08F1A7E70A34DD49" modified="2018-07-18" version="1">MQNIENSPNTDMDAEVSSVLEYARRAELILVIGNKNYSSWSMRPWVVLVAFDIPFKEIRILLDQPDTTSRIAEYSLAGRVPVLIDGDLTVWDSLAICEYLAEQYADKKLWPHNVAARASARSICAEMHGSFNALRAAMPMDIRSRHPGEGRTPHAQADIGRITEIWEECLSKYGHHQFLFGEFSIADAYFAPVVMRFHSYDVVLAPALQAYMERVIAHPAVARWILEAKAEIESLPDHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2X3</accession>
    <name>A0A2S9H2X3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0953</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94332">
        <property type="protein sequence ID" value="PRC94332"/>
        <property type="gene ID" value="S2091_0953"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="90" mass="10245" checksum="E81F84C0418F0607" modified="2018-07-18" version="1">MHTQQRPPRNTHLAIDTIDAYTQARDIVSDLSAIFEVLDHLALTDFSNKRITPILFRAGFGHATEQLKFIEEKISDAYKTLDELKVDSNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H313</accession>
    <name>A0A2S9H313_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">4'-phosphopantetheinyl transferase superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0996</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94375">
        <property type="protein sequence ID" value="PRC94375"/>
        <property type="gene ID" value="S2091_0996"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008897">
        <property type="term" value="F:holo-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.470.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008278">
        <property type="entry name" value="4-PPantetheinyl_Trfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037143">
        <property type="entry name" value="4-PPantetheinyl_Trfase_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01648">
        <property type="entry name" value="ACPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56214">
        <property type="entry name" value="SSF56214"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ACPS" evidence="2">
        <location>
            <begin position="126"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="258" mass="29313" checksum="A2CBA103B43988EE" modified="2018-07-18" version="1">MDEAFLLPPTIDPLGLPAHNAVAIYLLELDHSACRDSPQRYLSLLAALELANWQKIRPVERQWQYLQSRVLQRLVLGAYAECDPRSLTFHRDEWGRPTLAEHGELHFSLSHCASHVALAVGSDSVLGVDVETVVPVRSSFMHIACKFFHPDDLAQLMEVPEEQRYGRFLEQWTLKEAHLKALGLGMHKSMADCRFERTSAGLIVAHDRAPVEDRVAPNAFIAQRRMRGCQLALAYRYGRPVRFRYLNGDTALPWQDTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H334</accession>
    <name>A0A2S9H334_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phenylacetate-CoA oxygenase, PaaI subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0897</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94276">
        <property type="protein sequence ID" value="PRC94276"/>
        <property type="gene ID" value="S2091_0897"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010124">
        <property type="term" value="P:phenylacetate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012347">
        <property type="entry name" value="Ferritin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007814">
        <property type="entry name" value="PaaA_PaaC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011882">
        <property type="entry name" value="PaaC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05138">
        <property type="entry name" value="PaaA_PaaC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037834">
        <property type="entry name" value="PA_CoA_Oase3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="SSF47240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02158">
        <property type="entry name" value="PA_CoA_Oxy3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="256" mass="29050" checksum="34787EC355C93164" modified="2018-07-18" version="1">MNAVAESNEQLSQYLLRMGDNCLILSQRLCGWTGHGPTLEDDLALSNVALDLLGQARLWLDYASSLHPTKRSEDALAYWRDAHEFRNLLLLEQPNGNFADTQVRQFFFDSWHFLVLTALSNSTDEKVAAISTKALKEVDYHVRRSSHWMLRLGGGTELSRSKLILALEQHWNYVGELFEMDELEQEMHACGIGCDLGALHAEWLAYVNDVLGKVELALPSRTPFQSGGKRGKHGEHLLSMLMEMQYLQRVHPGAQW</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H347</accession>
    <name>A0A2S9H347_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Cytosine-specific methyltransferase</fullName>
            <ecNumber evidence="8">2.1.1.37</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_1019</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>a 2'-deoxycytidine in DNA + S-adenosyl-L-methionine = a 5-methyl-2'-deoxycytidine in DNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:13681"/>
            <dbReference type="Rhea" id="RHEA-COMP:11369"/>
            <dbReference type="Rhea" id="RHEA-COMP:11370"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:85452"/>
            <dbReference type="ChEBI" id="CHEBI:85454"/>
            <dbReference type="EC" id="2.1.1.37"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="6 7">Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.37" evidence="8"/>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94398">
        <property type="protein sequence ID" value="PRC94398"/>
        <property type="gene ID" value="S2091_1019"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003886">
        <property type="term" value="F:DNA (cytosine-5-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009307">
        <property type="term" value="P:DNA restriction-modification system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018117">
        <property type="entry name" value="C5_DNA_meth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001525">
        <property type="entry name" value="C5_MeTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031303">
        <property type="entry name" value="C5_meth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00145">
        <property type="entry name" value="DNA_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00105">
        <property type="entry name" value="C5METTRFRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00675">
        <property type="entry name" value="dcm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00094">
        <property type="entry name" value="C5_MTASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00095">
        <property type="entry name" value="C5_MTASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51679">
        <property type="entry name" value="SAM_MT_C5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6 8" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0680">Restriction system</keyword>
    <keyword evidence="4 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 6 8" id="KW-0808">Transferase</keyword>
    <feature type="active site" evidence="6">
        <location>
            <position position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC94398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="425" mass="48810" checksum="A0C17F9B6EAF325A" modified="2018-07-18" version="1">MDYVLETSDHDEAMSYLALARAKFTQTEIARHLKVDSRTVRRWEARQSSPQPYITAALKQLMLPIHRIPEPSDEFKFIDLFAGVGGIRHGFQAVGGQCVFTSEWNTYAQKTYETNYPDEHKIDGDITLIDEEDVPDHDVLLAGFPCQPFSIAGVSKKNSLGRSHGFADETQGTLFFDVARIIAAKRPRAFLLENVKNLLSHDKGRTFDVIKRTLSEELGYHIHYKVIDGAHYVPQHRERIIIVGFREPVAFDWNMLNLPEKNQIKLQSILHKTDGSEPVLAWDENKYFDHQQRCVPAKYTLTDNLWTYLQNYAAKHREKGNGFGYGMAYPDSITRTLSARYHKDGSEILVYQGEKKNPRRLTPRECARLMGYPDTFLIPVSDTRAYQQFGNSVVVNVISEIARIMKPFICENEMQYPEFPELIAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3L0</accession>
    <name>A0A2S9H3L0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0575</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94572">
        <property type="protein sequence ID" value="PRC94572"/>
        <property type="gene ID" value="S2091_0575"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010292">
        <property type="entry name" value="Uncharacterised_CreA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37952">
        <property type="entry name" value="PTHR37952"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05981">
        <property type="entry name" value="CreA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003174">
        <property type="entry name" value="CreA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015506390" evidence="1">
        <location>
            <begin position="27"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="162" mass="17754" checksum="297CDED44F867AB6" modified="2018-07-18" version="1">MQIKSRFFLLMSVPLLLLSALQTTSAETIGEVNTEFKFIGPDHKVVVEVFDDPKVAGVSCYLSRAKTGGFKGAIGIAEDKAESSVACRQIGEIKFNGPLPRQEEVFSERASIIFKHVRVIRMVDTKRNALVYLVYSDRLVDGSPKNSVTAVPVAANQVIPVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3N7</accession>
    <name>A0A2S9H3N7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">LysR substrate binding domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0583</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94580">
        <property type="protein sequence ID" value="PRC94580"/>
        <property type="gene ID" value="S2091_0583"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="15"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="318" mass="35357" checksum="656A4B1EBC0558BF" modified="2018-07-18" version="1">MKQKTRPMMGQLSDMDIRLLRIFKSVVDCGGMAASELELNIGTSSISRHIKDLEIRLGLTLCRRGRGGFSMTAEGEQIYQETLRLLSSTDQFRSSVDDIHRRMGGQLNVAVHDKTASNPAAKIHEAIALFSERAPEVALNMHVASSNPIERGVLDGQFQIGIIPDHRSSDSLTYANLFEETMLMFCGAKHPLFNATQDNLGWDDISAHHFACLGYHSHNMEISHQMGLSRKATGFDQESIATLILSGKYLGFLPDHYADGYVARGQMQVVKPDQFNYKCNFVGMLRRSPQPSRVSQAFWECLLLAHGKSASASVPFHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3T3</accession>
    <name>A0A2S9H3T3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_0630</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94627">
        <property type="protein sequence ID" value="PRC94627"/>
        <property type="gene ID" value="S2091_0630"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001034">
        <property type="entry name" value="DeoR_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013196">
        <property type="entry name" value="HTH_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028349">
        <property type="entry name" value="PafC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026881">
        <property type="entry name" value="WYL_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08279">
        <property type="entry name" value="HTH_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13280">
        <property type="entry name" value="WYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016838">
        <property type="entry name" value="PafC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51000">
        <property type="entry name" value="HTH_DEOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH deoR-type" evidence="3">
        <location>
            <begin position="4"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC94627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="317" mass="35066" checksum="FF207E9316F672AE" modified="2018-07-18" version="1">MANPTTRVLALLELLQTHELMSGAELARRLEIDPRTLRRYINTLESLGIPVMTERGRDGGYRLIHGFKLPPMMFTNDEALALGLGLVAARSLGLAATTPASNSALSKLERVMPEKLRQRMRAVGETVSLDIAKATSSGDPEILALLSAATRDQQSVRLHYLSPQQVQTDRKIDPYGLAYLNGSWYVVAHCHLRKDTRSFRLDRIQSADLLPMSFGKPADFDAMRYISSAIATIPRMHQVKVLLHTDLASAHAAIFSAFGMLEPIDDNTILTIQADDLGWVARELARLPFSFAIQEPAALKEVLAHHARELLKIGRLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3U3</accession>
    <name>A0A2S9H3U3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Bacterial extracellular solute-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0658</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94655">
        <property type="protein sequence ID" value="PRC94655"/>
        <property type="gene ID" value="S2091_0658"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006059">
        <property type="entry name" value="SBP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13416">
        <property type="entry name" value="SBP_bac_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015653874" evidence="1">
        <location>
            <begin position="31"/>
            <end position="446"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="446" mass="48651" checksum="3038643A3A2732C2" modified="2018-07-18" version="1">MKTSSFKPSYLASTLLLATTLGMASQSAMATELNIWIMSTTTQQQQDMKELLRPYLAKNPNLRVNVTVLNWESAWSKITAAAASGQGPDLLELGTTWVAAISSMGALEPLSAQQQNEVGGAKAFFPAVWGSTHRYDDTKIYALPWYADARAAFYRTDVFKKAGINPKDAFTNWGSFKQAMQKINGQMVDGKKIAALGYPGKNDWNVVHNLAPWIWNAGGDLLTADKKHSAINSPEALQAITYYTSFAAEGLVPSSALEKDSSQIESGFFNGQYAVIFTGSWILRQLNTPKAKGGQMDSVAAHNFGVESYPAGLKGNQTFFSGSDLAIMKSSKNKDEAWKLLSFMTSREAEVNYSKMSGMLPARQDAANDPTLMADPHYAEFIAQVKNGRHYPSVAGWGPLESVYLKNIGNMFDIVAGVKGKYTPQAIKQALDVTANEANDVLDESR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3Y8</accession>
    <name>A0A2S9H3Y8_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Citrate synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_0674</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>acetyl-CoA + H2O + oxaloacetate = citrate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16845"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:16947"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="EC" id="2.3.3.16"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate metabolism; tricarboxylic acid cycle; isocitrate from oxaloacetate: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 5 7">Belongs to the citrate synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94671">
        <property type="protein sequence ID" value="PRC94671"/>
        <property type="gene ID" value="S2091_0674"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00223">
        <property type="reaction ID" value="UER00717"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036440">
        <property type="term" value="F:citrate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011278">
        <property type="entry name" value="2-MeCitrate/Citrate_synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016142">
        <property type="entry name" value="Citrate_synth-like_lrg_a-sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016143">
        <property type="entry name" value="Citrate_synth-like_sm_a-sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002020">
        <property type="entry name" value="Citrate_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019810">
        <property type="entry name" value="Citrate_synthase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024176">
        <property type="entry name" value="Citrate_synthase_bac-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036969">
        <property type="entry name" value="Citrate_synthase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11739">
        <property type="entry name" value="PTHR11739"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00285">
        <property type="entry name" value="Citrate_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001369">
        <property type="entry name" value="Citrate_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00143">
        <property type="entry name" value="CITRTSNTHASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48256">
        <property type="entry name" value="SSF48256"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01800">
        <property type="entry name" value="cit_synth_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00480">
        <property type="entry name" value="CITRATE_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 7" id="KW-0808">Transferase</keyword>
    <feature type="active site" evidence="6">
        <location>
            <position position="294"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010566"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR001369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR001369-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC94671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="409" mass="45127" checksum="4A6FDC8C3083C30D" modified="2018-07-18" version="1">MPCLRSRNLSKTIVLSNKFTNIEENRMTEATTPFKPKKSVALSGVTAGNTALCTVGKTGNDLHYRGYDILDVATTCEFEEIAHLLVHGKLPNQAELLAYKNKLKALRGLPASLKAALECLPASAHPMDVMRTGVSALGCMLPEKDDHNLPGARDIADQLMASFGSMLLYWYHYSHNGRRIDVETSDDSIGGHFLHLLHGVAPSEEWISAMHTSLILYAEHEFNASTFAARVVAGTGSDMHSAIAGAIGALRGPKHGGANEVAFEIQKRYDNPDEAEADIKKRVENKEVVIGFGHPVYTISDPRNKVIKEVAKHLSQQAGSTKMFDIAERLETVMWDAKKMFPNLDWFSAVSYHMMGVPTAMFTPLFVIARTSGWAAHIIEQRIDNKIIRPSANYVGPEDLTFVPIKDRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H450</accession>
    <name>A0A2S9H450_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0649</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94646">
        <property type="protein sequence ID" value="PRC94646"/>
        <property type="gene ID" value="S2091_0649"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015429559" evidence="1">
        <location>
            <begin position="19"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="137" mass="15862" checksum="1A5B95D7DDB60F4F" modified="2018-07-18" version="1">MRKLFALLFLIFSSQAFANWDKVSSVAAFSNDEGNEYYWDLSTLRQQGHTFKIWTMLDTKSPTDSNFESGKKVQSVRKFIEIDCVEKNQRMLSYVENAGLGGTGATIYSESITSPWNPFTPHSWTDFLYQKFCRKQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4C7</accession>
    <name>A0A2S9H4C7_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Type IV pilus biogenesis and competence protein PilQ</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">S2091_0786</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Required for type IV pilus biogenesis and competence. Could function as a pore for exit of the pilus but also as a channel for entry of heme and antimicrobial agents and uptake of transforming DNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Homododecamer. Tetramer of trimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial secretin family. PilQ subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94783">
        <property type="protein sequence ID" value="PRC94783"/>
        <property type="gene ID" value="S2091_0786"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030420">
        <property type="term" value="P:establishment of competence for transformation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021731">
        <property type="entry name" value="AMIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001775">
        <property type="entry name" value="GspD/PilQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005644">
        <property type="entry name" value="NolW-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038591">
        <property type="entry name" value="NolW-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013355">
        <property type="entry name" value="Pilus_4_PilQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011662">
        <property type="entry name" value="Secretin/TonB_short_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004846">
        <property type="entry name" value="T2SS/T3SS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004845">
        <property type="entry name" value="T2SS_GspD_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11741">
        <property type="entry name" value="AMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00263">
        <property type="entry name" value="Secretin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03958">
        <property type="entry name" value="Secretin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00811">
        <property type="entry name" value="BCTERIALGSPD"/>
    </dbReference>
    <dbReference type="SMART" id="SM00965">
        <property type="entry name" value="STN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02515">
        <property type="entry name" value="IV_pilus_PilQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00875">
        <property type="entry name" value="T2SP_D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="8" id="KW-0178">Competence</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12" id="KW-0732">Signal</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015491177" description="Type IV pilus biogenesis and competence protein PilQ" evidence="12">
        <location>
            <begin position="36"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="domain" description="STN" evidence="13">
        <location>
            <begin position="308"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00014124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00025897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="PRC94783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="723" mass="77650" checksum="D954D42871DFC015" modified="2018-07-18" version="1">MRMLIKMRTTNTGWCSMFRLFLLVGALGLSAQASAQSNSIEQVTASQQGSNVIVKVTMKNPMDKVPLGFSTATPARIAIDFASTSNETGKSSVDINIGNVHTLNIVQAGDRSRLVFNLAKPLNYASVVENNLLVITIDGTGDVATALNSKGVPVAPLQANTGKQMLRDIDFRKGINGEGRIVIDLPSKQVGVDVHQQGNTIVADVLKTDLPEILRRRLDVTDFGTPVQTIETTAQGDNIHMVITPKGQWEHSVYQSDTQLVIEVKPIKVDPSKLTQGTQGYRGEKLSLNFQDVDVRSLLQVIAEVSGFSIITSDSVSGRVTLRLKDVPWDQALEIIMQQKGLDMRKNGPVIMVAPKDELLAKEKLEAEQKASIGDLEQLKTESFQLNYQKVASFKAAFGLSGSSPGIRILSKRGSAVVDERTNQMFVTDVPSRLDAVRQLVLKTDIPSRQVLIEARLVVATDDWSKNLGAQLGFTDLRTLQGGTAGFPVTGGTNAALTGTYQGVSDQTAQTAVNQRATQAFTQAGQFFSLPAAPIGGVNPGAVAVSLFSSAANRFLNMEISALEADGTGKVISSPRLVTADQVAAVVEQGTELPYQTATSSGATAITFQKANLRLEVTPQITPDGNIILDVEVNNDTQGVLTTAGYAINTQHLKTIVMVDNGGTVLLGGIYQETVQNSETKIPFLGDIPILGYLFKTTAKTKNKSELLIFLTPKIIADHIAVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4G9</accession>
    <name>A0A2S9H4G9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0026</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94831">
        <property type="protein sequence ID" value="PRC94831"/>
        <property type="gene ID" value="S2091_0026"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018062">
        <property type="entry name" value="HTH_AraC-typ_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00041">
        <property type="entry name" value="HTH_ARAC_FAMILY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="2">
        <location>
            <begin position="223"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="326" mass="35871" checksum="9687D986068F6346" modified="2018-07-18" version="1">MQPFLSLACSDAPIRIALLHIDPENGSGAGGLSLAGLVTPLRLVEQQLGAARIIVTLHRLSNSLSNIDDSELKKINKNVHLVLLIADELKSAPSHDEIRKLAQLCQQARFWGAVGAAVLWFANVGKMERIRSALPWALYAEANEVAEHAILMPNLFELDGHCLTCCGGAASIDFALTLIHAMFGADVQAHVMEALCVERVRNGDERQRIALQTRFGVLQPQLSEAVTLMENNIEETLSTDDIAQLVGLSRRQLERQFKQYLGTMPSRYYLELRLKKARQLLLDSNSSIVQIGLMCGFSSGAHFSTAFGTQFGITPREERQRKLSAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4N6</accession>
    <name>A0A2S9H4N6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0122</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94927">
        <property type="protein sequence ID" value="PRC94927"/>
        <property type="gene ID" value="S2091_0122"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015599736" evidence="1">
        <location>
            <begin position="25"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="380" mass="40098" checksum="BB504FF3D99AD693" modified="2018-07-18" version="1">MKNYFSSILPAVLILGSVMLTAHADEPKGFLETIHKHKTLASTTTDNGDLNPYAVVVAPVSSGVIEKDDVLVDNFNNISNLQGTGTTIVRYRPSTKETKLFAQVPQNLKDCPGGVGLTTAMTMLKSGWVIVGSTPSTDGTTKTKGAGCVLVFNSNGQHVATWAGPTINGPWGNMATVDRGDSAVLFISMAGFGLQGPEVVDPVSHYPVTTHEATVLRLELTIPEGKPPVLESQTVIGDGFAQRADRDNFLFGPTGLALGPDDTLYITNGLVNEITAIPDASTRTTSAKTGRLITKEGLLGWPLAMVMTPAGHLLVCNGKNGQAVEVNPITGKQIYAHWLDSNQAQSPPGNGDLFGLALTPDGKGIYYVEDDMNTLVLGAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4R9</accession>
    <name>A0A2S9H4R9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0175</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94980">
        <property type="protein sequence ID" value="PRC94980"/>
        <property type="gene ID" value="S2091_0175"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="83" mass="8970" checksum="BED01C3F50CB5255" modified="2018-07-18" version="1">MSSSINELETRLSGLKKLTGQLQADTRLLSTSLDEHSANDPLIESAKQLKVPMLMPLTIGTLLASALGEVESVENALKSIRHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4S9</accession>
    <name>A0A2S9H4S9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NUDIX domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0185</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94990">
        <property type="protein sequence ID" value="PRC94990"/>
        <property type="gene ID" value="S2091_0185"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010945">
        <property type="term" value="F:CoA pyrophosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03426">
        <property type="entry name" value="CoAse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045121">
        <property type="entry name" value="CoAse"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12992">
        <property type="entry name" value="PTHR12992"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="1">
        <location>
            <begin position="59"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="223" mass="25382" checksum="EA1E28D492C5D0D4" modified="2018-07-18" version="1">MSIPVFDPQSVPVDSIAGESVLEQTRLNLDWIRTRFADPPEWHPEITDELRLFSVDKTYTNASVLITLVQRAEGLNLLFTRRTAHLTHHAGQISFPGGRVELEDSSLIETALREAHEEIGLSRDYVEILGLLPDYYTGTGYRVTPVVAAVQLPLELQSDANEVAEIFEVPLAYLMDGSRHQLRSSVFPKQEVRRSFYTMPYQDYFIWGATAGMLRNLFHFLRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4W7</accession>
    <name>A0A2S9H4W7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Microcystin-dependent protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0202</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95007">
        <property type="protein sequence ID" value="PRC95007"/>
        <property type="gene ID" value="S2091_0202"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1340.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011083">
        <property type="entry name" value="Phage_tail_collar_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037053">
        <property type="entry name" value="Phage_tail_collar_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07484">
        <property type="entry name" value="Collar"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Collar" evidence="1">
        <location>
            <begin position="7"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC95007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="171" mass="18044" checksum="C415B57A66513036" modified="2018-07-18" version="1">MADQFIGEIRAFGFNYAPYEWAFCNGQLIPVQQNAALFAILGANYGGNGSTNFGLPNLQGRAIMGQVNGDINNPQGDAQVTITTATMPSHSHTLYGDVAHASSDQPANHLPARLLDANNNAFIAAVPPPALTTLSPATIGTVGNSLPHDNSQPYQVLNFCISLAGAWPQRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H508</accession>
    <name>A0A2S9H508_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0208</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95013">
        <property type="protein sequence ID" value="PRC95013"/>
        <property type="gene ID" value="S2091_0208"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="22"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC95013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="306" mass="34680" checksum="E429C7E59D149150" modified="2018-07-18" version="1">MSKPLRSLSGLIDFECAARWCSFKLAARELNKTPAAISQQIKQLEQTLGFALFTRQTRQLVITEKGQELASAVAKHLRELNAKVAALQTTNEEHVLRISTTHSFAMKWLTPRLHRFVERHPELDIRIESNDALVNLNDSSYDVAIRYSKIQDTADAAPLLREKLVVVYSPALLKKTVSTKKSATQSLISLLKFPLLFEGTPENWLRLLKENRIPDAHYDFSHGYSHSGLLVQAAVAAHGVALAPYSIAYEDIRKGALIIAPFKRLTSQYGYRVLYRAEEEPSLKTKLFDAWLHEEVDEMESHLIEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H534</accession>
    <name>A0A2S9H534_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Bcr/CflA family efflux transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_0289</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell inner membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Bcr/CmlA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95094">
        <property type="protein sequence ID" value="PRC95094"/>
        <property type="gene ID" value="S2091_0289"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042910">
        <property type="term" value="F:xenobiotic transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990961">
        <property type="term" value="P:xenobiotic detoxification by transmembrane export across the plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004812">
        <property type="entry name" value="Efflux_drug-R_Bcr/CmlA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00710">
        <property type="entry name" value="efflux_Bcr_CflA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="52"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="82"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="107"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="140"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="170"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="227"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="257"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="289"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="319"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="353"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="377"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="8">
        <location>
            <begin position="16"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC95094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="405" mass="44081" checksum="DF21A8A36149EA50" modified="2018-07-18" version="1">MSSNTASSARKQSTGLALLLASLAMLGPFSVDTYLPAFPAIQASLNVSAIEVQQTLTAYMLSFAFMMLWHGAISDALGRRNIILVSLFIFAVASLGCASAHSIHYLWAFRILQGLSAGAGMVVGRAIIRDMYSGPAAQRLLSLVTMIFSIAPAIAPILGGWVVMLLDWRWIFLFLCFYTVFLIWFCYKYLPESLPPEKRQEFSIPVLTNSYKAVFSSPSFHLQSGTVAFNFAGLFLYVASAPVFLTQHLGLTSQQFGWQFVPMVAGIFLGALGANRLAGRISLFRQVRIGYVFLAGAACCNVIYHFFFPPAIPWSVTPLFFYAIGMSLVAPGVTLMTLDLFPNTRGIVASCQSCAVTFLGAIVAGVIAPVLENSPIWLALGQLGFSCCAMLCWHLSKKAHNKLLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H553</accession>
    <name>A0A2S9H553_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_0309</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95114">
        <property type="protein sequence ID" value="PRC95114"/>
        <property type="gene ID" value="S2091_0309"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="4"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="140"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC95114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="210" mass="23007" checksum="C110326CCF04A678" modified="2018-07-18" version="1">MTHYTLIVEDHPLYREGLGDTLSLVLTDTVVLKACSAEEGLLMTDHLHDVRLICIDLGLPKIQGIDAVSIFRTKFPRAVLIVISGNEQTELQQLAIERGANTFIPKSASPNEIAVLVHRAMAGEWLTPNFDLAVSRTVSPGQLKPFLTIRQSEVLELLAMGMSNKQIARQLEVAEVTVKLHVTGIFRAFGANCRSQALLVARKSGLLPDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H560</accession>
    <name>A0A2S9H560_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_0258</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95063">
        <property type="protein sequence ID" value="PRC95063"/>
        <property type="gene ID" value="S2091_0258"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014757">
        <property type="entry name" value="Tscrpt_reg_IclR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005471">
        <property type="entry name" value="Tscrpt_reg_IclR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09339">
        <property type="entry name" value="HTH_IclR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01614">
        <property type="entry name" value="IclR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00346">
        <property type="entry name" value="HTH_ICLR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51077">
        <property type="entry name" value="HTH_ICLR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51078">
        <property type="entry name" value="ICLR_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH iclR-type" evidence="3">
        <location>
            <begin position="15"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="domain" description="IclR-ED" evidence="4">
        <location>
            <begin position="77"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC95063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="260" mass="28668" checksum="D211D28C67FC5BA0" modified="2018-07-18" version="1">MNSSTPVTDPSKTSIQVIERMVSLLNALAKYPDPVSLKELSKVTGLHPSTAHRILNDMVLTRFVDRSEPGTYRLGMRLLELGNVVKSRLNVREAAIEAMRSLHRQTHQTVNLSVRQGDEIVYIDRAFSERSGMQVVRAIGGRAPLHLTSTGKLFLSVDEPKAIRAYATRTGLAGHNRNSITDLSKLEHELLQVRLLGYARDNEELELGVRCMAAGIMDDSGKLIAGLSISAPADRLMEDWLDPLIATAKQISATLGYELI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5M0</accession>
    <name>A0A2S9H5M0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0443</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95248">
        <property type="protein sequence ID" value="PRC95248"/>
        <property type="gene ID" value="S2091_0443"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.429.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014347">
        <property type="entry name" value="Tautomerase/MIF_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55331">
        <property type="entry name" value="SSF55331"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC95248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="150" mass="16607" checksum="27A67680034E4C56" modified="2018-07-18" version="1">MPNILVKIPKGSFPPEHRTALVRRLNDAAASSEQIPDEPKKRFMCWIIIDEVEPGSWTCGALDMTEQIIPCIAMIYLPAGVLDDAARALYVARVHEAFKQSLPTSEQRQLATSVVLHDVTDGTWGGNGIIWRLPEFAQAAGFMHLQALIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GS77</accession>
    <name>A0A2S9GS77_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4726</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000055">
        <property type="protein sequence ID" value="PRC90567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90567">
        <property type="protein sequence ID" value="PRC90567"/>
        <property type="gene ID" value="S2091_4726"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC90567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="41" mass="4505" checksum="C6B5856179F7A959" modified="2018-07-18" version="1">MIDIRFSQTGYSSSISPTVLCRGRVKTRIRAAIKLLALNPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSC7</accession>
    <name>A0A2S9GSC7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">RHS repeat-associated core domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4685</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000044">
        <property type="protein sequence ID" value="PRC90617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90617">
        <property type="protein sequence ID" value="PRC90617"/>
        <property type="gene ID" value="S2091_4685"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008964">
        <property type="entry name" value="Invasin/intimin_cell_adhesion"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001826">
        <property type="entry name" value="RHS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022385">
        <property type="entry name" value="Rhs_assc_core"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00394">
        <property type="entry name" value="RHSPROTEIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49373">
        <property type="entry name" value="SSF49373"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03696">
        <property type="entry name" value="Rhs_assc_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015660667" evidence="1">
        <location>
            <begin position="17"/>
            <end position="1199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="1199" mass="120878" checksum="93B4E4DF5A4E50FA" modified="2018-07-18" version="1">MAAMLLSVLTQQPVMASTKQTITFAALASKTYGVAPFTVSATSSSGLAVTFTSTTTAVCTVSGATVTVVAPGTCTIVANQAGNTTYSAATQVAQSLTVAKEAQTITFAALTGKSYGTAPFTVSATSSAKLATTFTSATTAICTVSGSIVTLVAPGTCTIDANQAGNVNYNAAPQVAESFTVTKGTQTITFAALTGKSYGTAPFAVSATSSANLAVAFTSATTSVCTVSGSTVTLVAPGTCTIDANQAGNTDYSAAPQVAQSMTVAKEAQTISFATLAGKTYGAAPFTVSATSSANLAVAFTSATTSVCTVSGSTVTLVAPGTCTINANQAGNTLYSAAAQVANSLTVAQEAQTITFTALAGKPYGAAPFTVSATSSANLAVAFTSATTSVCTVSGSTVTLLAGGTCTINANQVGNTTYSAAPQVANSFAVTTEAQTINFASLASQQFGAAPFALTATSTSGLAVSFTSTTTPVCTVSGSTVTLVSAGTCTINANQTGSSNYSAATQVTQSFTVTAEAQTISFTAPATQQFGAAPFALSATSSSGLAISFMSSTTPVCTVSGSIVTLVSAGTCTITANQVGSSNYSAATQVTQSFIITTEAQTINFAAPGNQQFGAAPFALTATSSSGLAISFTSSTTPVCTVSGSTVTLVSAGTCTIAADQAGSSNFSAAPEVSQSFTVTAEAQTISFATLANQQFGAAPFVLSATSSSGLAISFMSSTTPVCTVSGSTVTLVSAGTCTIAADQAGSGNFSAAPEVSQSFTVTAETQTISFTAPANQQFGAAPFELSATSSSGLAISFTSSTTPVCTVSGSTVTLVSAGTCTIAANQVGSSTYSPAPQVMQSFTVTVAPLLITLTSPTITQSLTAPAALTLTATATDSSGTITQVAFFNGTGLMGTVTQPPYSIVIPNTVAGSYQLTAQVTDNNGLTATSAPVTIAVAAGSGSAAEQIYYISTDQLNTPRLITDSDGNTVWQWDGEAFGSTPPKTEVTGAGQFTFNLRYPGQYYDAETNLHYNYFRDYDPSTGRYTESDPIGLHAGLSTFGYVGGNPTAFRDPAGLCPMCFAAYFFIAENSVTLGTIGAVGLEVVSGVPNPSSGIVFEGRVVTESAYDVYLGFRNGEPVYAGISKDLACRTAQHGDRFDAFWKVTSSQVTKDQARAIEQTLINQNPQFENQINSIASNRSWYVQAVQWGSLWLSLNGWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSC9</accession>
    <name>A0A2S9GSC9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Periplasmic binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4665</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000042">
        <property type="protein sequence ID" value="PRC90629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90629">
        <property type="protein sequence ID" value="PRC90629"/>
        <property type="gene ID" value="S2091_4665"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002491">
        <property type="entry name" value="ABC_transptr_periplasmic_BD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01497">
        <property type="entry name" value="Peripla_BP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50983">
        <property type="entry name" value="FE_B12_PBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe/B12 periplasmic-binding" evidence="1">
        <location>
            <begin position="22"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="267" mass="29832" checksum="D1230CA43CD2C760" modified="2018-07-18" version="1">MQWQDAIGAWHSSINVNDSAPRIVSLVPSITELLCDLGLAPHLVGRTGFCIHPHEVVQNIPKIGGTKDVNIEKIRALAPTHLIVNIDENEKPCVEQLAQFIPHVIVTHPQTLEDNLPLFNLLGGIFNVTERAQQLSQQFTDALSALQLSLPVPLISQRVLYCIWKDPWMTVSSNTYIANMLSHIGWQIIPTGTARYPVFTWSEQLVNDIDLVLLSSEPYRFTEQHVDALEQQCGKPVLLLDGEMISWYGSRSIAGINYLRELVAGAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSH5</accession>
    <name>A0A2S9GSH5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4613</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000039">
        <property type="protein sequence ID" value="PRC90663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90663">
        <property type="protein sequence ID" value="PRC90663"/>
        <property type="gene ID" value="S2091_4613"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="51"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="535" mass="56097" checksum="0C9B098F568B992E" modified="2018-07-18" version="1">MNNYTIKQVPLIQRQGPLTNIYDLIAQSLLPVLLVSSTMLFTGCGGGGGGSSTTAASSSSSSAPTSPSSSAPTPTVPPAPIQAVVANYSVKTNVIPVTGAGKVFGMQANFFDDGFIPPNPISNWGFQNPLIPAVNADGSMDVAWLDYSGTSGPSTTGLSALGAINITHINPDLSTGSTMATGLLSYKLLGFTKDTAGAFYIAYNVDHPFKNAIAGDANNVNGNELHIAKSGTASFTMKTWDTLVFGDMDNTKDQSKGNPGEAGLGVLGFDVVNQKLALYVAHRMAWGDNGTRHQAGYFRYVDPASGNIVAPGNSHPTDTGTGWFYSHNFNQRLLLDNGTAYLLAHGDAYSRQLGFAAITATGYSASDSTVFNQSYLAINGTEGDNVTNTETGQFIKLSNGDFAIVYTTSQGRIARDVQIVIASGVNGTTKSSAWLTSNTGNIQAIMPKLEVSGNNILVSYGLWDSTTRTNKAIAWHFATVDTSLNLISASNPIPGIEFITDLPLIRFSSGPNVGQLAWVSGNGQGSLSVNLIQTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSM6</accession>
    <name>A0A2S9GSM6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ABC-type proline/glycine betaine transport system permease component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_4598</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000038">
        <property type="protein sequence ID" value="PRC90705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90705">
        <property type="protein sequence ID" value="PRC90705"/>
        <property type="gene ID" value="S2091_4598"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="134"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="158"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="201"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="281"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="312"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="154"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC90705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="379" mass="40996" checksum="3F45679E845EFE39" modified="2018-07-18" version="1">MSDIPDNSWAAVGHPESGAPTDLQPDTFVDPWAAMSTNSDSGNADWLNTAPDLSASNTGIDWLNPFEHKILPLDSWVNDGLTWVIGNFRETFQHVRVPIEGTLTLVENALQTTPALLTIALFGLLAWQFSSRRLAIGAVLSLLLIGFLGVWSEAMTTLSLVLTSVGFCIVIGLPLGILAARSNLVEKIVRPLLDAMQTTPAFVYLVPVVMLFGIGNVAGVLVTIIFAMAPLVRLTNLGIRQVRPDLVEASRSFGASSWQLLTKVQLPLALPTIMAGVNQTLMLALSMVVIASMIAVGGLGQMVLRGIGRLDMGLATIGGLGIVILAILLDRLTQALTKQQRNQRWYQQGPVGFVWRLMQRFVVKNPVRSNKKLTSLQGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSP1</accession>
    <name>A0A2S9GSP1_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">YceI domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_4565</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000037">
        <property type="protein sequence ID" value="PRC90739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90739">
        <property type="protein sequence ID" value="PRC90739"/>
        <property type="gene ID" value="S2091_4565"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007372">
        <property type="entry name" value="Lipid/polyisoprenoid-bd_YceI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036761">
        <property type="entry name" value="TTHA0802/YceI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04264">
        <property type="entry name" value="YceI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00867">
        <property type="entry name" value="YceI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101874">
        <property type="entry name" value="SSF101874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015678341" description="YceI domain-containing protein" evidence="1">
        <location>
            <begin position="22"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="domain" description="YceI" evidence="2">
        <location>
            <begin position="26"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC90739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="187" mass="20383" checksum="97D1BE2C2A07D233" modified="2018-07-18" version="1">MKLFKTLAIAAVLTLPIIGHAEEFNTVQSDKSTLTFGFKQMGVPMDGKFKKFSVQMNFDPTNLVASKAQFDLDLASIDVGSDEGNDEVVGKQWFNTKVFPKASFTTSSIRSLENNHYDVMGSLRIKGRTKIVTAPATITIQGKNASFDGSLVILRSDFNIGEGPWASFDTVANVVQIKFHLLASAGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GST0</accession>
    <name>A0A2S9GST0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4518</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000036">
        <property type="protein sequence ID" value="PRC90770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90770">
        <property type="protein sequence ID" value="PRC90770"/>
        <property type="gene ID" value="S2091_4518"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC90770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="66" mass="7162" checksum="0B5B3C4198D8BA80" modified="2018-07-18" version="1">MQTFICSLIIIAALLYTANRWMPLKLKQRFMQMLGKTPVVNQSTGGCSSCSSCGNCGSNSTKLAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSY8</accession>
    <name>A0A2S9GSY8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative zinc-finger</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_4471</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000035">
        <property type="protein sequence ID" value="PRC90808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90808">
        <property type="protein sequence ID" value="PRC90808"/>
        <property type="gene ID" value="S2091_4471"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1320">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041916">
        <property type="entry name" value="Anti_sigma_zinc_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027383">
        <property type="entry name" value="Znf_put"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13490">
        <property type="entry name" value="zf-HC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="87"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="domain" description="zf-HC2" evidence="2">
        <location>
            <begin position="3"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC90808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="259" mass="29269" checksum="FD1441EF84A25C33" modified="2018-07-18" version="1">MDCNESQKLMSAYLDEELDPSSAAKYAEHLLSCTACNSQYEELLRLGSTLKTHSTNYTAPSHLRYRIQADLDALKPRKKSSRKWSWAWINFGVASACSFAFALTMSLYLAVPSEADRLDQEIVASHYRSLLANHLADVASSDHHTVKPWFSGKLDYSPPVFDFVDQGFTLLGGRLDYVNQRSVAALAYRHDKHLINLFVWPDKSQNESPAKNTSMQGFHLLEWTHSGMAYRAISDMNAQELANFRALLISQIDKETKTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GT20</accession>
    <name>A0A2S9GT20_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4436</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000034">
        <property type="protein sequence ID" value="PRC90855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90855">
        <property type="protein sequence ID" value="PRC90855"/>
        <property type="gene ID" value="S2091_4436"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC90855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="123" mass="13916" checksum="1586617454ACC5FA" modified="2018-07-18" version="1">MEKIETHDIETESEEGVRLSDESSEIRKLYRVLEITERYCGKDASIALRRQVEEIVRDDVHISGERSMVICLLDLPSSSAYPLVMAEISKLKSGITEDEGKLERKKLVYLKACLTAIDEALSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GT81</accession>
    <name>A0A2S9GT81_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 9">Urocanate hydratase</fullName>
            <shortName evidence="9">Urocanase</shortName>
            <ecNumber evidence="4 9">4.2.1.49</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8 9">Imidazolonepropionate hydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">hutU</name>
        <name evidence="13" type="ORF">S2091_4391</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>4-imidazolone-5-propanoate = H2O + trans-urocanate</text>
            <dbReference type="Rhea" id="RHEA:13101"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:17771"/>
            <dbReference type="ChEBI" id="CHEBI:77893"/>
            <dbReference type="EC" id="4.2.1.49"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
        <text evidence="9">Binds 1 NAD(+) per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 9">Amino-acid degradation; L-histidine degradation into L-glutamate; N-formimidoyl-L-glutamate from L-histidine: step 2/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the urocanase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.49" evidence="4 9"/>
    <dbReference type="EMBL" id="PUGF01000033">
        <property type="protein sequence ID" value="PRC90898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90898">
        <property type="protein sequence ID" value="PRC90898"/>
        <property type="gene ID" value="S2091_4391"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00379">
        <property type="reaction ID" value="UER00550"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016153">
        <property type="term" value="F:urocanate hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019556">
        <property type="term" value="P:histidine catabolic process to glutamate and formamide"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019557">
        <property type="term" value="P:histidine catabolic process to glutamate and formate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10730">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00577">
        <property type="entry name" value="HutU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023637">
        <property type="entry name" value="Urocanase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035401">
        <property type="entry name" value="Urocanase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038364">
        <property type="entry name" value="Urocanase_central_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023636">
        <property type="entry name" value="Urocanase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035400">
        <property type="entry name" value="Urocanase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035085">
        <property type="entry name" value="Urocanase_Rossmann-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036190">
        <property type="entry name" value="Urocanase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12216">
        <property type="entry name" value="PTHR12216"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01175">
        <property type="entry name" value="Urocanase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17392">
        <property type="entry name" value="Urocanase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17391">
        <property type="entry name" value="Urocanase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001423">
        <property type="entry name" value="Urocanate_hydrat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111326">
        <property type="entry name" value="SSF111326"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01228">
        <property type="entry name" value="hutU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01233">
        <property type="entry name" value="UROCANASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 9" id="KW-0369">Histidine metabolism</keyword>
    <keyword evidence="7 9" id="KW-0456">Lyase</keyword>
    <keyword evidence="6 9" id="KW-0520">NAD</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Urocanase_N" evidence="11">
        <location>
            <begin position="16"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="domain" description="Urocanase" evidence="10">
        <location>
            <begin position="145"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="domain" description="Urocanase_C" evidence="12">
        <location>
            <begin position="362"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="421"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="57"/>
            <end position="58"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="135"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="181"/>
            <end position="183"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="201"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="247"/>
            <end position="248"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="272"/>
            <end position="276"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="282"/>
            <end position="283"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="333"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="503"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF17391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF17392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PRC90898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="566" mass="61612" checksum="961033E39770AA12" modified="2018-07-18" version="1">MNSLKDDPRYDATRVIRATRGPEKTCKTWVAEAAYRMIQNNLDAEVAENPTHLVVYGGIGRAARDWACYDQILASLKELGEDETLLVQSGKPVGVFKTHEDAPRVLIANSNLVPKWANWEHFNELDRKGLFMYGQMTAGSWIYIGTQGIVQGTFETFEEAGRQHFNGDWAGRWILTAGLGGMGGAQPLAATFAGAVSLNIECQQTSIDFRLRTRYVDKQARDLDHALELVAEHCAKKEAISIALLGNAAEILPELVKRAKAGGIKPDLVTDQTSAHDLINGYLPIGWTVAQWKAAQLDSKQHARLTAEAAAGCVAHVNAMLEFHKMGIATVDYGNNIRQVAFDAGVKNAFDFPGFVPAYIRPLFCDGKGPFRWVALSGDPEDIYKTDAKIKELFPQNAGVHRWLDMARERIAFQGLPARICWLGLGERHIAGLAFNEMVKNGELKAPIVIGRDHLDTGSVASPNRETESMKDGTDAVSDWPLLNALLNTAGGASWVSLHHGGGVGMGYSQHSGMVIVADGTDAAAKRLARVLVNDSGSGVMRHADAGYETAVACAKRNKLNLPMIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GT85</accession>
    <name>A0A2S9GT85_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Gamma-aminobutyrate permease and related permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_4404</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000033">
        <property type="protein sequence ID" value="PRC90911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90911">
        <property type="protein sequence ID" value="PRC90911"/>
        <property type="gene ID" value="S2091_4404"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004841">
        <property type="entry name" value="AA-permease/SLC12A_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004840">
        <property type="entry name" value="Amoino_acid_permease_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00324">
        <property type="entry name" value="AA_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00218">
        <property type="entry name" value="AMINO_ACID_PERMEASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="25"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="52"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="96"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="130"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="164"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="203"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="239"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="285"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="336"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="362"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="407"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="431"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="domain" description="AA_permease" evidence="7">
        <location>
            <begin position="23"/>
            <end position="443"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC90911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="459" mass="50136" checksum="4EC5DFF14F504F8C" modified="2018-07-18" version="1">MNNFDKITQREHGLQKKLTAGQMSMIAIGGAIGTGLFLGSKFAIGFAGPSVILSYAIGAFITLLLMGCLAEMTIAHPTTGSFGAYAEHYISPLAGFLVRYAYWAAIVLAVGTEITAVAEYMQFWFKDVPAWIWIVSFSSVLIAVNAFSVKAFGTTEYWFSTIKIFAIIGFIILGAYVVISPDLPEYGLHNYSLEGGFLPHGWTGMWVAVVISIFSYLSVEMIAVAAGEAENPEQAVKKAFYATILRLGIFYLTTLALIVAIVPWTEIEQGQSPFVTVMQTLKIPYAAGILNFVVVVAALSAMNSQLYITTRMMFSLARGGDAPAGLGKLNAHGIPFNALLLSTSGIALATIVYTLFPDTAFTLMVALSMFGALFTWMMIFVTHYFFRIHRNNNGGPALSFQLKGFPVTTLLGFILMLAILITTAFTEIFRMTLVFGIPFLALLILLFYFQKNRKPPIPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTB0</accession>
    <name>A0A2S9GTB0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Tat (Twin-arginine translocation) pathway signal sequence</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_4337</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000032">
        <property type="protein sequence ID" value="PRC90936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90936">
        <property type="protein sequence ID" value="PRC90936"/>
        <property type="gene ID" value="S2091_4337"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002937">
        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019546">
        <property type="entry name" value="TAT_signal_bac_arc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01409">
        <property type="entry name" value="TAT_signal_seq"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amino_oxidase" evidence="2">
        <location>
            <begin position="71"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC90936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="517" mass="54969" checksum="88ECA1B80A9313AE" modified="2018-07-18" version="1">MKKNPKSPQHATENTSTNPVDTPSETKGISRRQVLRTGAAAAVTLAVGWSNSSNAAKANTAPRIVIVGAGLAGLRCAHSLWNRTKPIASTIYDADTSHLGGRCWSLRGFFDNGLIAEQGGTFISTTDSNILALAQSLGLQTETVNGGALPKGQFVAWVNNSTYSENAQQNDWNNLAWPAFKASYALTGPTSSYNNYTPEAFRLDNMSCLDYLTEIGLDPNSRLGQLIQTIQVGGGGTAADSSALSMIQWLGNDQTFDGGGFDEALHIKGGNDQIISGMISQLPANSIKQGYQLTALCKNNDGSYNCTFNNNGNSSNVTADHVVLALPFSTLRLVNLTGAGLSTLKLTAINQQGMGQGSKITSQFSTKTWPALNYNGVTNTGPSGYQTAWDESVPLGPKGHPALMVTFPADSSLTGAVRGATPSADINWFLAQIENVYPGTTAAYSGKSYESRWALSPWQRGTYHYYRVGQMTLFAGYEAAQEGNIHFAGEHTVIYDSTMQSAVLSGERAAAEVAAQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTC6</accession>
    <name>A0A2S9GTC6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Polysaccharide deacetylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4364</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000032">
        <property type="protein sequence ID" value="PRC90963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90963">
        <property type="protein sequence ID" value="PRC90963"/>
        <property type="gene ID" value="S2091_4364"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002509">
        <property type="entry name" value="NODB_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01522">
        <property type="entry name" value="Polysacc_deac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="SSF88713"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51677">
        <property type="entry name" value="NODB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NodB homology" evidence="1">
        <location>
            <begin position="87"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="326" mass="36413" checksum="54C2C951A8732ED5" modified="2018-07-18" version="1">MTFSLINNLTSRFIRVVGNQIAPSAVGQGRLCILIYHRILEHVDPLLESEPDVASFRWQMEALASCFNVLPLHEALDTLRNGRMPPRAVCITFDDGYRSTHDLALPILKEFNFPATVFVTTSYLDGSNMWNDRILEAVRSLPVGPLDLTNSGLGIHPISSLADRENAADKLIRAAKYLPSEQRLDLSLKLESLIGAAHRSGLMLTHDMVRTLVENGIEVGGHTVTHPILTKLDDQRAKEEIVGCKQELEAIIGKPVRLFAYPNGKVGMDYDERHVQMAKEAGYSAAFITTMGPATGQTDPYQIPRGRPWDKSQLMFKLRLLRWLAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTC9</accession>
    <name>A0A2S9GTC9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyl transferase 4-like domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4366</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000032">
        <property type="protein sequence ID" value="PRC90965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90965">
        <property type="protein sequence ID" value="PRC90965"/>
        <property type="gene ID" value="S2091_4366"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="1">
        <location>
            <begin position="13"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="385" mass="43358" checksum="954FD1B178E67154" modified="2018-07-18" version="1">MKILYHHRTSSKDGQAVHIKEMIAALRDLGHEVIVVAPAGNQHTSFGSDDNFVVMLKRYVPKFCYELMEFAYNWIAYRALAKAVKQHQPDCLYERYNLFLLAGIWIKRKHHLPMLLEVNSPIFEERERYDGLSLKRLARWSQATTWRAADFVLPVTQVMAEIIQSYGVAPEKMLVIHNGINTKEFDNVASHNSVKSALGLENKLVLGFTGFVRDWHGLDKVIDMIANDPPEAGRHLMVVGDGPARPALEKQAEALNVTNRVSFTGIIGREKIPEYVAAFDIALQPAVVAYASPLKLFEYLALGKAIVAPAQANIRELLFDEHNAILFDPNQADGMPKAIDRLCKDDALRLSVSKNASATIADKQLTWKANAERVVQLFERLRHHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTJ9</accession>
    <name>A0A2S9GTJ9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phage Tail Collar Domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_4232</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000030">
        <property type="protein sequence ID" value="PRC91044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91044">
        <property type="protein sequence ID" value="PRC91044"/>
        <property type="gene ID" value="S2091_4232"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1340.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011083">
        <property type="entry name" value="Phage_tail_collar_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037053">
        <property type="entry name" value="Phage_tail_collar_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07484">
        <property type="entry name" value="Collar"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Collar" evidence="2">
        <location>
            <begin position="9"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="123"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="192" mass="19902" checksum="AE99595E3A100FFC" modified="2018-07-18" version="1">MADTSFPIGTIVSIFGADPNNPPEGWLPCIGGTFSSDQYEQLSILLGGTTLPNFAGMTLIGAGTNSANVAWPTSNTKGATNQNSDGTYGASTHQLSLAEIPPHQHNGVGDSTQNGWPYGFDSAGNNNRGLSGTDTDNGFYPSGWAGGQGTTASSPGTTNSFKLMQPSYALYFYIYAGTSDESTVSGKDVDHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTP5</accession>
    <name>A0A2S9GTP5_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 10">Transaldolase</fullName>
            <ecNumber evidence="6 10">2.2.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">tal</name>
        <name evidence="11" type="ORF">S2091_4179</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 10">Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = beta-D-fructose 6-phosphate + D-erythrose 4-phosphate</text>
            <dbReference type="Rhea" id="RHEA:17053"/>
            <dbReference type="ChEBI" id="CHEBI:16897"/>
            <dbReference type="ChEBI" id="CHEBI:57483"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="2.2.1.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 10">Carbohydrate degradation; pentose phosphate pathway; D-glyceraldehyde 3-phosphate and beta-D-fructose 6-phosphate from D-ribose 5-phosphate and D-xylulose 5-phosphate (non-oxidative stage): step 2/3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the transaldolase family. Type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.2.1.2" evidence="6 10"/>
    <dbReference type="EMBL" id="PUGF01000029">
        <property type="protein sequence ID" value="PRC91083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91083">
        <property type="protein sequence ID" value="PRC91083"/>
        <property type="gene ID" value="S2091_4179"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00115">
        <property type="reaction ID" value="UER00414"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004801">
        <property type="term" value="F:transaldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006098">
        <property type="term" value="P:pentose-phosphate shunt"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00957">
        <property type="entry name" value="Transaldolase_TalAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00492">
        <property type="entry name" value="Transaldolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001585">
        <property type="entry name" value="TAL/FSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004730">
        <property type="entry name" value="Transaldolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018225">
        <property type="entry name" value="Transaldolase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10683">
        <property type="entry name" value="PTHR10683"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10683:SF18">
        <property type="entry name" value="PTHR10683:SF18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00923">
        <property type="entry name" value="TAL_FSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00874">
        <property type="entry name" value="talAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01054">
        <property type="entry name" value="TRANSALDOLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 10" id="KW-0570">Pentose shunt</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 10" id="KW-0704">Schiff base</keyword>
    <keyword evidence="7 10" id="KW-0808">Transferase</keyword>
    <feature type="active site" description="Schiff-base intermediate with substrate" evidence="10">
        <location>
            <position position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003518"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00013151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC91083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="311" mass="33871" checksum="D7F80C65191FC1D2" modified="2018-07-18" version="1">MNQLEQLKQVTTVVADTGDFQSMKIFAPQDATTNPSLILKAVQKPDYLPLLSQAISAHPQATNSEIIDHLLIAFGLQILALIPGRVSTETDAHLSFDTAATVAKGRHLIALYEAAGVTRERVLIKIASTWEGIQAAAILEKEGIHCNMTLLFSLEQAVTCAQAGAQLISPFVGRIYDWYKKNTGQEYSAENDPGVQSVKQIYNYYRKFGFKTEIMGASFRNTGQITELAGCDLLTISPELLQKLSESSDPVPSKLNQAAAKACDLSAITMTEASFRLAVNNNAMAAEKLAEGIRLFCADTVKLEQLIASMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTS3</accession>
    <name>A0A2S9GTS3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4194</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000029">
        <property type="protein sequence ID" value="PRC91098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91098">
        <property type="protein sequence ID" value="PRC91098"/>
        <property type="gene ID" value="S2091_4194"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="42" mass="4684" checksum="80FDBB3B8E6C63ED" modified="2018-07-18" version="1">MLLNAYKKADPFAAQLNAMEQQGIIDPLINIKSRKIKSLIPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTS6</accession>
    <name>A0A2S9GTS6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Choline dehydrogenase and related flavoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_4133</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000028">
        <property type="protein sequence ID" value="PRC91132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91132">
        <property type="protein sequence ID" value="PRC91132"/>
        <property type="gene ID" value="S2091_4133"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="PTHR11552"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000137">
        <property type="entry name" value="Alcohol_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00623">
        <property type="entry name" value="GMC_OXRED_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00624">
        <property type="entry name" value="GMC_OXRED_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GMC_OxRdtase_N" evidence="4">
        <location>
            <begin position="89"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="domain" description="GMC_OxRdtase_N" evidence="5">
        <location>
            <begin position="261"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="99"/>
            <end position="102"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="226"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000137-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS00623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS00624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC91132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="552" mass="60063" checksum="1F98F03073B1A5BC" modified="2018-07-18" version="1">MNTPTTENTMFDYVIIGGGSAGCVLANRLSADPAISVCLLEAGGDNQSALIRTPGAFGYFMFSRKYNWAYRAKADPTVCKGRRMFLPRGKGLGGSSAINGMVYIRGFRRDYDEWAALGNTGWSFDEVLPYFKRSEDNARGASSHHGSGGPLHVSDAEMHYPISQQFLEAAKQTGLPLTDDFNGAKPEGVGIYQFTIRDGQRCGVAAAFLDPARRRSNLTVITHAHVTQLNLIGKRVSGVNYEVNGQPCFVAAKCEVILSAGAYGSPQLLMLSGIGDPFELKRHKIACKHVLPGVGQNLQEHVDSCVLTSSHDHGGTSLTPTGIARMCKAIWQYYRHKKGLLRASATEIGAYLCSSPEHVIPDVQYHIIPVLFDDSGRDIALLAKTGYSVHVYVVRPKSRGSVRLASNDPYAEPVVDQCLLEHPDDIKSLLNGIRLARRWLAAPIFSASRKKELVPGAERVSDEEILEACRNHLGNGFHPVGTCKMGIDEMAVVGPDLKVHGLDNLRVVDASIMPNVVSGNTNAPTIMIAEKASDMILELRTMSKLPEFAHCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTT4</accession>
    <name>A0A2S9GTT4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Dehydrogenases with different specificities (Related to short-chain alcohol dehydrogenases)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4136</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000028">
        <property type="protein sequence ID" value="PRC91135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91135">
        <property type="protein sequence ID" value="PRC91135"/>
        <property type="gene ID" value="S2091_4136"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="258" mass="27195" checksum="63AE457679C7B7F5" modified="2018-07-18" version="1">MRILDKVIVITGGASGLGLATAHYLAEEKGAKIAIFDLNQEAGNKVVEEIGADRALFVQTDVSDEASVQQAVDAVMTKFSAIHVCINGAATPAGFKVLNREGKAAPLAKFAQTTAININGVFNVMSKCVEQMAKNEPEAGEERGVVINVSSGAAYEGQVGQCAYASSKAAIIGMNMPAARELGSIGVRVNAIAPGLFLTPMAAALDEKILNSLKEQVEAPPRLGDMREFSHCCAFIIENAYVNAETIRLDGAARLRSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GU04</accession>
    <name>A0A2S9GU04_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4085</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000027">
        <property type="protein sequence ID" value="PRC91190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91190">
        <property type="protein sequence ID" value="PRC91190"/>
        <property type="gene ID" value="S2091_4085"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018643">
        <property type="entry name" value="DUF2069_membrane"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09842">
        <property type="entry name" value="DUF2069"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="91"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="129" mass="14164" checksum="65C9F8669F35DEC9" modified="2018-07-18" version="1">MNKSALYAHGATASLIAIIALGIIGEMWLAPLRPGGSWLVLKVVPLLFSLRGVMKRDNYTMQWSSMLILLYFTEGIVRATSDKTTLSAQLGWLQVALCLAFFFCVLSYLRPLKKAAKAAAKKAQEQASQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GU64</accession>
    <name>A0A2S9GU64_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">UPF0761 membrane protein S2091_4035</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_4035</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the UPF0761 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000026">
        <property type="protein sequence ID" value="PRC91250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91250">
        <property type="protein sequence ID" value="PRC91250"/>
        <property type="gene ID" value="S2091_4035"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00672">
        <property type="entry name" value="UPF0761"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023679">
        <property type="entry name" value="UPF0761_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017039">
        <property type="entry name" value="Virul_fac_BrkB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30213">
        <property type="entry name" value="PTHR30213"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03631">
        <property type="entry name" value="Virul_fac_BrkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00765">
        <property type="entry name" value="yihY_not_rbn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="52"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="116"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="154"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="193"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="261"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC91250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="429" mass="48189" checksum="91CAB928BB4ADD43" modified="2018-07-18" version="1">MFMTSPFIENLKSRIKSARLFGWRVTEIHSLIHFAIRRIVAGHLAQVAGSLTFTTVLALVPMLTIALAIFTAFPLFTTFRASLEAYFIQSLMPHAISSNILGYLNQFATKATRLSAYGAVALMVTSIAMLATIDRVFNQIWRVKQKRPLIKRMMVYWALITLAPLLMGVSITVTSYLFAATSDVVGALPGSKMLYTAASIIFTTCAFSLLYIIVPNRSIDWRDAAWGGLVAGVLFEIAKRIFAAFVIHIPTYTIVYGAVAIVPIFLIWIYTSWLITLFGAVIAASLPIVKYERWWHKPKPGSRFIDAIALLETLYAARARTNQAGISSWEIRQKTRFGFDEIEGLLTQMTKAGWVGRLHADEIVIKKPTPLVGSEWWVLLVNPNYLTLSQVYRLFVFETQADARLTQKVEIAIEQGLQESLEDYFLAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUB2</accession>
    <name>A0A2S9GUB2_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Fumarylacetoacetase</fullName>
            <ecNumber evidence="4">3.7.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">S2091_3965</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid degradation; L-phenylalanine degradation; acetoacetate and fumarate from L-phenylalanine: step 6/6.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.7.1.2" evidence="4"/>
    <dbReference type="EMBL" id="PUGF01000025">
        <property type="protein sequence ID" value="PRC91294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91294">
        <property type="protein sequence ID" value="PRC91294"/>
        <property type="gene ID" value="S2091_3965"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00139">
        <property type="reaction ID" value="UER00341"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004334">
        <property type="term" value="F:fumarylacetoacetase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006559">
        <property type="term" value="P:L-phenylalanine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006572">
        <property type="term" value="P:tyrosine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.850.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005959">
        <property type="entry name" value="Fumarylacetoacetase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011234">
        <property type="entry name" value="Fumarylacetoacetase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036663">
        <property type="entry name" value="Fumarylacetoacetase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015377">
        <property type="entry name" value="Fumarylacetoacetase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036462">
        <property type="entry name" value="Fumarylacetoacetase_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43069">
        <property type="entry name" value="PTHR43069"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01557">
        <property type="entry name" value="FAA_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09298">
        <property type="entry name" value="FAA_hydrolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56529">
        <property type="entry name" value="SSF56529"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63433">
        <property type="entry name" value="SSF63433"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01266">
        <property type="entry name" value="fum_ac_acetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0585">Phenylalanine catabolism</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0828">Tyrosine catabolism</keyword>
    <feature type="domain" description="FAA_hydrolase_N" evidence="10">
        <location>
            <begin position="29"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="domain" description="FAA_hydrolase" evidence="9">
        <location>
            <begin position="135"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="182"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF09298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC91294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="431" mass="46681" checksum="75E3294E0B3EFD79" modified="2018-07-18" version="1">MNTLNATHNPSLTSWVAAANQPDQDFPIQNLPFGVFTTASQAQAHVGVAIGDAILDLAVLQQAGLINVAGDVFNAASLNLFINLGAAVWSSVRAQVSDLLRADNATLRDNAALRSQALVAQSAAQMLLPVEIGGYTDFYSSKEHATNVGSMFRDPKNALLPNWLEIPIGYNGRASSVIVSDTPIRRPNGQTKAPTQERPEFGPCKKLDIELETGFIIGRGNALGEPIRCENAEQHIFGMVLLNDWSARDIQTWEYVPLGPFNSKTFASTISPWVVTMEALAPFRVATPAQEPQPLSYLQHKPEVKYGVDIQLEVQLTPEQSQQATTICRTNFKDMYWSMAQQLTHHTASGCNTRIGDLMGSGTISGATPDSFGSLLELTWNGANPLALTDGSTRQFIQDGDELTIRGWAQGANYRVGFGLCRGKILPALAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUB9</accession>
    <name>A0A2S9GUB9_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase</fullName>
            <ecNumber evidence="9">2.3.1.117</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Tetrahydrodipicolinate N-succinyltransferase</fullName>
            <shortName evidence="9">THDP succinyltransferase</shortName>
            <shortName evidence="9">THP succinyltransferase</shortName>
            <shortName evidence="9">Tetrahydropicolinate succinylase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">dapD</name>
        <name evidence="11" type="ORF">S2091_3998</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>(S)-2,3,4,5-tetrahydrodipicolinate + H2O + succinyl-CoA = (S)-2-succinylamino-6-oxoheptanedioate + CoA</text>
            <dbReference type="Rhea" id="RHEA:17325"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15685"/>
            <dbReference type="ChEBI" id="CHEBI:16845"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57292"/>
            <dbReference type="EC" id="2.3.1.117"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="9">Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; LL-2,6-diaminopimelate from (S)-tetrahydrodipicolinate (succinylase route): step 1/3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homotrimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the transferase hexapeptide repeat family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.117" evidence="9"/>
    <dbReference type="EMBL" id="PUGF01000025">
        <property type="protein sequence ID" value="PRC91327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91327">
        <property type="protein sequence ID" value="PRC91327"/>
        <property type="gene ID" value="S2091_3998"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00034">
        <property type="reaction ID" value="UER00019"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008666">
        <property type="term" value="F:2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019877">
        <property type="term" value="P:diaminopimelate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.166.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00811">
        <property type="entry name" value="DapD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005664">
        <property type="entry name" value="DapD_Trfase_Hexpep_rpt_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018357">
        <property type="entry name" value="Hexapep_transf_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023180">
        <property type="entry name" value="THP_succinylTrfase_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037133">
        <property type="entry name" value="THP_succinylTrfase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14602">
        <property type="entry name" value="Hexapep_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14805">
        <property type="entry name" value="THDPS_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00965">
        <property type="entry name" value="dapD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00101">
        <property type="entry name" value="HEXAPEP_TRANSFERASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3 9" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 9" id="KW-0220">Diaminopimelate biosynthesis</keyword>
    <keyword evidence="7 9" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 9 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="THDPS_N_2" evidence="10">
        <location>
            <begin position="4"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="109"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="146"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF14805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC91327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="278" mass="30137" checksum="8B582003D80A73E3" modified="2018-07-18" version="1">MTQQLQQIIDLSWEDRASFTPKSAPTELRLAVAEVIAKLDNGSLRVAEKLTDGSGQWHVNQWVKKAVLLSFRLEDNIVMPSGEHMQFFDKVPTKFAHYTAEDFVKGGFRVVPPAVARRGSFIAKNVVLMPSYVNIGAYVDEGAMVDTWATVGSCAQIGKNVHLSGGVGIGGVLEPMQANPTIIEDNCFIGARSEIVEGVIVEENSVISMGVYIGQSTKIYDRATGEVTYGRIPSGSVVVSGNLPSPDGKYSLYCAVIVKRVDAQTRSKTSINELLRGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUQ5</accession>
    <name>A0A2S9GUQ5_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Proline--tRNA ligase</fullName>
            <ecNumber evidence="9">6.1.1.15</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Prolyl-tRNA synthetase</fullName>
            <shortName evidence="9">ProRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">proS</name>
        <name evidence="11" type="ORF">S2091_3931</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>ATP + L-proline + tRNA(Pro) = AMP + diphosphate + L-prolyl-tRNA(Pro)</text>
            <dbReference type="Rhea" id="RHEA:14305"/>
            <dbReference type="Rhea" id="RHEA-COMP:9700"/>
            <dbReference type="Rhea" id="RHEA-COMP:9702"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:60039"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78532"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.15"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="2 9">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="9">Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.15" evidence="9"/>
    <dbReference type="EMBL" id="PUGF01000024">
        <property type="protein sequence ID" value="PRC91386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91386">
        <property type="protein sequence ID" value="PRC91386"/>
        <property type="gene ID" value="S2091_3931"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA editing activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004827">
        <property type="term" value="F:proline-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006433">
        <property type="term" value="P:prolyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00861">
        <property type="entry name" value="ProRS_anticodon_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00779">
        <property type="entry name" value="ProRS_core_prok"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.960.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01569">
        <property type="entry name" value="Pro_tRNA_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002314">
        <property type="entry name" value="aa-tRNA-synt_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004154">
        <property type="entry name" value="Anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036621">
        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002316">
        <property type="entry name" value="Pro-tRNA-ligase_IIa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004500">
        <property type="entry name" value="Pro-tRNA-synth_IIa_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023717">
        <property type="entry name" value="Pro-tRNA-Synthase_IIa_type1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044140">
        <property type="entry name" value="ProRS_anticodon_short"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033730">
        <property type="entry name" value="ProRS_core_prok"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036754">
        <property type="entry name" value="YbaK/aa-tRNA-synt-asso_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007214">
        <property type="entry name" value="YbaK/aa-tRNA-synth-assoc-dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03129">
        <property type="entry name" value="HGTP_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00587">
        <property type="entry name" value="tRNA-synt_2b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04073">
        <property type="entry name" value="tRNA_edit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001535">
        <property type="entry name" value="ProRS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01046">
        <property type="entry name" value="TRNASYNTHPRO"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55826">
        <property type="entry name" value="SSF55826"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00409">
        <property type="entry name" value="proS_fam_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 9 11" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="10">
        <location>
            <begin position="33"/>
            <end position="473"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC91386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="577" mass="64230" checksum="78A6331F9C25CEA7" modified="2018-07-18" version="1">MRATRFFISTLKEAPADAEIISHKLMMRAGLIKRLGSGIYNYMPMGLRVIRKVEAIVREEMNRAGAIEMMMPVVQPAELWQETGRWQKYGAELLRVKDRHGRDFIIQPTSEEVITDVARSDIKSYRQLPINFYHIQTKFRDERRPRFGLMRGREFTMKDAYSFDRDVASMQVSYKIMFDAYVRIFQRFGLQFRAVAADNGAIGGTGSHEFHVIADTGEDDLVYCPTSDYAANMEAAVALPTTTERVAPTQQLTKVSTPGTVKCEQVSELLGISLDKNVKSLVFAVDGTEDGSVKKQLWLLLLRADHQLNEIKMHKVAGLANARMATEEEIVEWFGCVPGYLGPIGTKLPINIVADHTVAMMTDFVCGANEADYHLTGVNWERDLPLPMVADIRNVQAGDPSPDGKGVLAIQRGIEVGHVFQLGTSYSEAMKATFLDENGKPQFLQMGCYGIGVTRILGAAIEQNFDEKGIVWPAALAPFSVVLCPMSYDRSEQVKTETDNLYVALQAAGVDVILDDRGERPGAMFADWELIGVPHRIVIGERGLKEGKLEYQGRRETAATAVSVDEMVAFIQEKLAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUR2</accession>
    <name>A0A2S9GUR2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_3882</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000023">
        <property type="protein sequence ID" value="PRC91467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91467">
        <property type="protein sequence ID" value="PRC91467"/>
        <property type="gene ID" value="S2091_3882"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="264"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="113"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="142"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="539"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="230"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="142"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC91467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="584" mass="65792" checksum="DFB8F0C57E0C5068" modified="2018-07-18" version="1">MQVPVSGATEDVLVPNCIKAKIESLDGELIDIPRVEIVIPNQVNQVIYINFSTRKLMQEPAIKFTVALTCGASLQRTYALLLDYSESPSAAPLTLPSVETPVTQITAITNTDRSATKSVLPKQPKKNHPAPPVIVDTVKKLEAERKVEPTQAKKEPVKASKRNGGTGKNVLKVTNEEALSDFDLKMSQTITEQTPASADQQRSQENRLAQARFAALLRGEDPLSAAQTATNLEQQKNKSLSAEVERLKQQNKLKEKTEQSTPSWMIWLASVATLLFLALIGMLIVTVRQSRQNKDKTWWDPTAEQKKNVVEIVDSLQSSAEKGNLDPSSISESQENSVIAANPYDEPIIYPHNKVEPSPKYKRMGLPALEDTNSSTFNFFTHRGQSIHIEEISDITQEAEFWMSVNDPNRAIEILEPQSFDENQTTPVAWLYLLDLYRMVADEEKYSELRLRFKRKFNAYIPNFHENIDPDSLRNFEDFPHLTANCCALWNTDEILPYLESLLVDDREGERIGFDLPVYRDILMLISISAEFHRAKKQPSTAIAPKDTIKPAEKAASEDAETNDYSDSLNFDLLDFKLDDKDKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUT0</accession>
    <name>A0A2S9GUT0_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ATP-dependent RNA helicase RhlE</fullName>
            <ecNumber evidence="5">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rhlE</name>
        <name evidence="12" type="ORF">S2091_3885</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>ATP + H2O = ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the DEAD box helicase family. RhlE subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="5"/>
    <dbReference type="EMBL" id="PUGF01000023">
        <property type="protein sequence ID" value="PRC91470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91470">
        <property type="protein sequence ID" value="PRC91470"/>
        <property type="gene ID" value="S2091_3885"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042255">
        <property type="term" value="P:ribosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00968">
        <property type="entry name" value="DEAD_helicase_RhlE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028622">
        <property type="entry name" value="DEAD_helicase_RhlE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5 7" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 5 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 5 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="Q_MOTIF" evidence="11">
        <location>
            <begin position="2"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="9">
        <location>
            <begin position="33"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="10">
        <location>
            <begin position="238"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="386"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="6">
        <location>
            <begin position="2"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="441"/>
            <end position="455"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PRC91470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="455" mass="48806" checksum="7A590DE72B19D08B" modified="2018-07-18" version="1">MTTFSELGLAEEILRAVSEQGYTTPTPIQLQAIPAVLTGQDLLAGAQTGTGKTAGFTLPLLQRLTTLAKPSASPTARRPIRALILTPTRELAAQVEESVRTYGKYLPLTSGVIFGGVGINPQIKLLKSGVDTLVATPGRLLDHIGQGTIDLSHVNILVLDEADRMLDMGFIRDIRKILALLPPKRQNLLFSATFSNEIKELADKLLNSPAMIEVARRNSTVEVISQKLHPVDRDRKHPLLAHLIKTLSWSQVLVFTRTKHGANKLVEQLEKAEITSMAIHGNKSQSARTKALAEFKDGSLQVLVATDIAARGIDIDQLPHVVNYDLPNVPEDYVHRIGRTGRAGAGGEAVSLVCVDELKLLADIEKFIKRKIVSEVVAGFEPDLNAQPQPIQLRSHPAHRPGSGANSGQKRAPAKPSGNKAAPRAPGSPAAARPHGGAAPNTSARRNSSGSRGRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUU9</accession>
    <name>A0A2S9GUU9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Bacterial transferase hexapeptide (Six repeats)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3759</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000022">
        <property type="protein sequence ID" value="PRC91481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91481">
        <property type="protein sequence ID" value="PRC91481"/>
        <property type="gene ID" value="S2091_3759"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03360">
        <property type="entry name" value="LbH_AT_putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041561">
        <property type="entry name" value="PglD_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020019">
        <property type="entry name" value="Sia_OAcTrfase_NeuD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17836">
        <property type="entry name" value="PglD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PglD_N" evidence="1">
        <location>
            <begin position="8"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF17836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="201" mass="21289" checksum="18036F3E47B4D05A" modified="2018-07-18" version="1">MTQKYKPKIILLGGGGHCAACIDVIEQEGKFEIAGIIDNEASPEFVCGYPRLGDDNILGSLPSSVEYALITVGQINSPAIRIRLFELTNSLGFTHPTIISPRAYVSKHAVIGKGTIVMHDALINVRASVGSNCIINSKALIEHDAVIEDNCHISTAAVVNGGARIRRGSFLGSNAATTELAISLENAFVKAGTLFRGISND</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVF9</accession>
    <name>A0A2S9GVF9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3653</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000020">
        <property type="protein sequence ID" value="PRC91715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91715">
        <property type="protein sequence ID" value="PRC91715"/>
        <property type="gene ID" value="S2091_3653"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014508">
        <property type="entry name" value="UCP020555_TPR-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16068">
        <property type="entry name" value="DUF4810"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF020555">
        <property type="entry name" value="UCP020555"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="117" mass="13237" checksum="69DA1E6FFBA92740" modified="2018-07-18" version="1">MTKKIVITLAAASVLLSGCHTQPKTLYQWEGYQPQVYQYFKGESPEQQIAILEKGLEIIKAKGNMPPPGYHAHLGLLYSGIGKQDQVIQEFQTEKTLFPESSAYMDFLLNKMKKSEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVK4</accession>
    <name>A0A2S9GVK4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NADH:flavin oxidoreductase / NADH oxidase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3514</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000019">
        <property type="protein sequence ID" value="PRC91759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91759">
        <property type="protein sequence ID" value="PRC91759"/>
        <property type="gene ID" value="S2091_3514"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003959">
        <property type="term" value="F:NADPH dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02932">
        <property type="entry name" value="OYE_YqiM_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001155">
        <property type="entry name" value="OxRdtase_FMN_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044152">
        <property type="entry name" value="YqjM-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43303">
        <property type="entry name" value="PTHR43303"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00724">
        <property type="entry name" value="Oxidored_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD_binding_3" evidence="2">
        <location>
            <begin position="7"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="domain" description="Oxidored_FMN" evidence="1">
        <location>
            <begin position="418"/>
            <end position="747"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="792" mass="88287" checksum="F1C5F3C3D3A32380" modified="2018-07-18" version="1">MKNTNMNILCIGGGPAGLYFGLLMKLQNPEHQITVVERNRPYDTFGWGVVFSDQTLGNLVQSDDISAQQILQAFNHWDDIDVHFKGQKITSSGHGFCGIGRKHLLNILQKRCEDLGVRLVFENDVQDELALAEQYQADLVIAADGLNSRIRTKYAASYQPDIETRLCRFVWLGTKKQFSAFTFAFEETEFGWFQAHAYQYDAELSTFIIEAPEEVWFKAGLDQMEQAEAAVFCEKIFAKYLDGHALMSNASHLRGSTNWIKFPRIICQNWVHTVQLDSKFVPIVLMGDAAHTAHFSIGSGTKLALEDAIELAACFKQYGAQGMESVLEHYQESRAIDVIKIQSAARNSMEWFENVSRYTAMQAPQFAYSLLTRSQRLSHDNLRLRDAAYISNYEQWLANQVQQSNPDNKFENKPVPPMFLPFQLRGVRLKNRVVVSPMAQYSAINGVAGDYHLVHLGSRAMGGAGLVFAEMTCVSADARITPACPGLYSPEHTVAWARIVNFVHTNSDAKIAMQLGHAGAKGSTKRAWDGIDQPLGEDNWPLVAASEQCYYPGVSQIARAASLDDMQRIQDDFVMATIAADKAGFDWLELHCAHGYFLSSFISPLTNHRTDAYGGSLENRCRYPLEVFAAIREVWPADKPISVRISAHDWVEGGITPSDAVLIARFFKQAGADMIDCSAGQVSKQEKPVYGRMFQTPFSDRIRNEVDIPTIAVGAITDADQVNSIIASGRADLCALARPHLADPAWTLHEAAKSGFSDISWPVQYQAGKLQLERNLAREKQLQQVISQSLGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVQ5</accession>
    <name>A0A2S9GVQ5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Outer membrane efflux protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3557</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000019">
        <property type="protein sequence ID" value="PRC91802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91802">
        <property type="protein sequence ID" value="PRC91802"/>
        <property type="gene ID" value="S2091_3557"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015562">
        <property type="term" value="F:efflux transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003423">
        <property type="entry name" value="OMP_efflux"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02321">
        <property type="entry name" value="OEP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015785958" evidence="2">
        <location>
            <begin position="26"/>
            <end position="451"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="451" mass="50331" checksum="E50A6F8665E4FF6D" modified="2018-07-18" version="1">MKKLFSARLVLASSAMLLSACSTFSTDSGFSDIAHLAQGELRKQVTWQRTDNESQMAQEKVSQLLAESLSVDDVVQIALLNNKELQANFYQLGIAEADFVQAGRMQNPGLTVGRLAQGGAIEVDRGLTFNLMHLLTQPYTRQMEQHRFEQTKQEVALQMLRLANETRKSYYMAVAANQTVEYAQQVQKLADAGSELGHRMQQVGNFNQLQQAREQGFYTDAQLTLARAEQAQIRAKEKLTRLLGLANSAATFILPHKLAELPASMDESASLEQVAMSQRIDIQIARLETKQLADNLGLNKATRFINVLNVGAERNTFTAEPVQRGYVVSLELPIFDSGDAKVAKAEAQYMQALNRTAAIAITARSEVREAYQVYRASFEIAKRYRDEIVPRNKRISEQNQLRYNGMLIDVFELLADARAQISSVNSAIEATRDFWLAAADLDMSLNGKPNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVR8</accession>
    <name>A0A2S9GVR8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Multicopper oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_3556</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000019">
        <property type="protein sequence ID" value="PRC91801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91801">
        <property type="protein sequence ID" value="PRC91801"/>
        <property type="gene ID" value="S2091_3556"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011706">
        <property type="entry name" value="Cu-oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045087">
        <property type="entry name" value="Cu-oxidase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011707">
        <property type="entry name" value="Cu-oxidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002355">
        <property type="entry name" value="Cu_oxidase_Cu_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709">
        <property type="entry name" value="PTHR11709"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07731">
        <property type="entry name" value="Cu-oxidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07732">
        <property type="entry name" value="Cu-oxidase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="SSF49503"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00080">
        <property type="entry name" value="MULTICOPPER_OXIDASE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015640180" evidence="5">
        <location>
            <begin position="33"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="7">
        <location>
            <begin position="93"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="6">
        <location>
            <begin position="225"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="415"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="426"/>
            <end position="440"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF07731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC91801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="471" mass="52061" checksum="0E22C8C017F28C06" modified="2018-07-18" version="1">MNSRRNFLSGFGRFGTIAAALSAASVSKVAMATLPELITQTKPDTMPPLVPNNGRPYNPVVTLNGWTLPWRMNQGVKEFHLVTEPVLREMAPGLTAHLWGYNGQSPGPTIEVVEGDRVRIFVTNKLPEHTSVHWHGQRLPNGMDGVSGLTQAPIQPGKTMVYEFIARRPGTFMYHPHADEMSQMAMGLMGSWVTHPKGRHPQIEEVDRDFIFLLNAYDIEPGAYTPKVSTMLDFNLWSWNSRVFPGIDPLVVRKNDKVRIRVGNLTMTNHPIHIHGHEFQVTGTDGGPVPRSARWPEVTTDVAVGQMRQIEFIADVEGDWAFHCHKAHHTMNAMGHNTANMIGVEQADIAKKISDLIPDYMSMGESGMAGMSSMAMPLPENTLPMMSGVGPFGSVDMGGMFSVLKVRKNQKTGDYKDPGWYQHPTGSVAQEWQGSQPDAIRSKQAGGELMPLAQPQAVEVQIRKPTGHSQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVW6</accession>
    <name>A0A2S9GVW6_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RNA polymerase sigma factor FliA</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">RNA polymerase sigma factor for flagellar operon</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Sigma F</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Sigma-28</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">fliA</name>
        <name evidence="8" type="ORF">S2091_3406</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the sigma-70 factor family. FliA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000018">
        <property type="protein sequence ID" value="PRC91850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91850">
        <property type="protein sequence ID" value="PRC91850"/>
        <property type="gene ID" value="S2091_3406"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed 5'-3' RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00962">
        <property type="entry name" value="Sigma70_FliA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000943">
        <property type="entry name" value="RNA_pol_sigma70"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007624">
        <property type="entry name" value="RNA_pol_sigma70_r3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007630">
        <property type="entry name" value="RNA_pol_sigma70_r4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012845">
        <property type="entry name" value="RNA_pol_sigma_FliA_WhiG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028617">
        <property type="entry name" value="Sigma70_FliA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04539">
        <property type="entry name" value="Sigma70_r3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04545">
        <property type="entry name" value="Sigma70_r4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000770">
        <property type="entry name" value="RNA_pol_sigma-SigE/K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00046">
        <property type="entry name" value="SIGMA70FCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02479">
        <property type="entry name" value="FliA_WhiG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00715">
        <property type="entry name" value="SIGMA70_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00716">
        <property type="entry name" value="SIGMA70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="4 5" id="KW-0804">Transcription</keyword>
    <keyword evidence="1 5" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="RNA_pol_sigma70" evidence="6">
        <location>
            <begin position="40"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="domain" description="RNA_pol_sigma70" evidence="7">
        <location>
            <begin position="204"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="5">
        <location>
            <begin position="205"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Sigma-70 factor domain-2" evidence="5">
        <location>
            <begin position="13"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Sigma-70 factor domain-4" evidence="5">
        <location>
            <begin position="183"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Interaction with polymerase core subunit RpoC" evidence="5">
        <location>
            <begin position="40"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS00715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS00716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC91850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="243" mass="27683" checksum="DA353AE45391B36E" modified="2018-07-18" version="1">MYNATGKTDKNHLLSEHAPLVKRLAYQLKAKLPPSVEVDDLIQAGMIGLLDAITRYEDNHGAQFETYAIQRIRGSMLDELRNSDWLPRGVRQTMRKIEEAIQQLQQRLGRPPSETEVAKQLKIPLAEYQERLTESGGHQLVYYEDFHDSDSKEHFLDRYCSDVSGDPLQSLLRGDFRATVISAIDALPDREKLLMGLYYEQELNLKEVGAVMGVSESRVSQLHTQAVARLRAFLREKAWTGQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVZ1</accession>
    <name>A0A2S9GVZ1_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha</fullName>
            <shortName evidence="10">ACCase subunit alpha</shortName>
            <shortName evidence="10">Acetyl-CoA carboxylase carboxyltransferase subunit alpha</shortName>
            <ecNumber evidence="10">2.1.3.15</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">accA</name>
        <name evidence="12" type="ORF">S2091_3440</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>acetyl-CoA + N(6)-carboxybiotinyl-L-lysyl-[protein] = malonyl-CoA + N(6)-biotinyl-L-lysyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:54728"/>
            <dbReference type="Rhea" id="RHEA-COMP:10505"/>
            <dbReference type="Rhea" id="RHEA-COMP:10506"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:57384"/>
            <dbReference type="ChEBI" id="CHEBI:83144"/>
            <dbReference type="ChEBI" id="CHEBI:83145"/>
            <dbReference type="EC" id="2.1.3.15"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 10">Lipid metabolism; malonyl-CoA biosynthesis; malonyl-CoA from acetyl-CoA: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the AccA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.3.15" evidence="10"/>
    <dbReference type="EMBL" id="PUGF01000018">
        <property type="protein sequence ID" value="PRC91884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91884">
        <property type="protein sequence ID" value="PRC91884"/>
        <property type="gene ID" value="S2091_3440"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00655">
        <property type="reaction ID" value="UER00711"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009317">
        <property type="term" value="C:acetyl-CoA carboxylase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003989">
        <property type="term" value="F:acetyl-CoA carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016743">
        <property type="term" value="F:carboxyl- or carbamoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:2001295">
        <property type="term" value="P:malonyl-CoA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00823">
        <property type="entry name" value="AcetylCoA_CT_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001095">
        <property type="entry name" value="Acetyl_CoA_COase_a_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011763">
        <property type="entry name" value="COA_CT_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42853">
        <property type="entry name" value="PTHR42853"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03255">
        <property type="entry name" value="ACCA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01069">
        <property type="entry name" value="ACCCTRFRASEA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00513">
        <property type="entry name" value="accA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50989">
        <property type="entry name" value="COA_CT_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 10" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="6 10" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="3 10" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="8 10" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="CoA carboxyltransferase C-terminal" evidence="11">
        <location>
            <begin position="40"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PRC91884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="324" mass="36050" checksum="230A29E27D8FE732" modified="2018-07-18" version="1">MTKTTFLNFEQSVADLESKIDELRFVQDDSAVDISEEIDRLSKKSQLLTKDIYAKLTPWQVSQISRHPQRPYTLDYINEIFTDFHELHGDRSFADDQAIVGGMARFNGQACMVMGHQKGRDTKERALRNFGMPKPEGYRKAMRLMKLAEKFNLPIFTFIDTTGAWPGIDAEERGQSEAIGHNLYVMAELKVPLIATIIGEGGSGGALAMAVGDAVLMLQYATYSVISPEGCASILWKTSERASDAAEALGLTAHRLKAMGLIDKIISEPLGGAHRDPKQMCVLVKRALADTLRQFQGVKTQDLLTARHEKLMSYGKYKETKSAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GW35</accession>
    <name>A0A2S9GW35_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3279</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000017">
        <property type="protein sequence ID" value="PRC91937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91937">
        <property type="protein sequence ID" value="PRC91937"/>
        <property type="gene ID" value="S2091_3279"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="71" mass="8478" checksum="FD0A1A2E473BD987" modified="2018-07-18" version="1">MNIWPIVLIRFIASNDCFEVPMLTLFKFTSRNKQHIEIFPQCHIYGIFKKMKILSVKLVEYPEQANAFSIW</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWB4</accession>
    <name>A0A2S9GWB4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ornithine/acetylornithine aminotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3354</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000017">
        <property type="protein sequence ID" value="PRC92012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92012">
        <property type="protein sequence ID" value="PRC92012"/>
        <property type="gene ID" value="S2091_3354"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00610">
        <property type="entry name" value="OAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000521">
        <property type="entry name" value="Transaminase_4ab_Lys_Orn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00600">
        <property type="entry name" value="AA_TRANSFER_CLASS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="1 2" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="400" mass="43392" checksum="0E46898290ACDD3A" modified="2018-07-18" version="1">MEFNLADTDALMFITARPEIVFTEGHGMWLSDHNGKKYLDFMQGWAVNCLGHSPQCVVDALTEQAKKLINPSPAFYNQPMLEFANLLVENSCFDKVFFANSGAEANEGAVKLARKWGQLNKNGAFEIITFDHGFHGRTLAMMSASGKPGWDTIFAPQVSGFVKAELNDIASVEQCITANTVAVMLEPVQGEGGVLPASREFMQALRALTEKHQILLIVDEVQTGIGRCGELFAYQLAQIEPDIMTLAKGIGAGVPLSALLCRAEVACFVPGDQGGTYCGNPLMTAVGAAVFKELLRPEFMPSVREKSAYLSQQLQALSDRFGLQGERGEGLLRALKLGTPIGSKIVEAARNLEPVGLLLNSPKPDLLRFMPALNVTNAEIDQMINLLAGLIQVEMIEATE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWH4</accession>
    <name>A0A2S9GWH4_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Peptide-methionine (R)-S-oxide reductase</fullName>
            <ecNumber evidence="2">1.8.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_3176</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[thioredoxin]-disulfide + H2O + L-methionyl-[protein] = [thioredoxin]-dithiol + L-methionyl-(R)-S-oxide-[protein]</text>
            <dbReference type="Rhea" id="RHEA:24164"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="Rhea" id="RHEA-COMP:12313"/>
            <dbReference type="Rhea" id="RHEA-COMP:12314"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16044"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:45764"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="EC" id="1.8.4.12"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.8.4.12" evidence="2"/>
    <dbReference type="EMBL" id="PUGF01000016">
        <property type="protein sequence ID" value="PRC92041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92041">
        <property type="protein sequence ID" value="PRC92041"/>
        <property type="gene ID" value="S2091_3176"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033743">
        <property type="term" value="F:peptide-methionine (R)-S-oxide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030091">
        <property type="term" value="P:protein repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028427">
        <property type="entry name" value="Met_Sox_Rdtase_MsrB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002579">
        <property type="entry name" value="Met_Sox_Rdtase_MsrB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011057">
        <property type="entry name" value="Mss4-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10173">
        <property type="entry name" value="PTHR10173"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01641">
        <property type="entry name" value="SelR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51316">
        <property type="entry name" value="SSF51316"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00357">
        <property type="entry name" value="TIGR00357"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51790">
        <property type="entry name" value="MSRB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MsrB" evidence="4">
        <location>
            <begin position="80"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC92041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="203" mass="21894" checksum="23C2E3B3D890435A" modified="2018-07-18" version="1">MISIHKPQQQADKPANQIAPTRRAVMLVGIGALLANAPLARAIAAALSAPPQTSLVAIENFSAAGKSTGVVRLPKLVKSDAEWAKLLPVAAYQVTRHEGTERPYSGKYWNNHADGIYHCICCDTALFDSKTKFESGTGWPSFWQTISAVNVIKNTDTTLGMQRDAISCRLCDAHLGHVFDDGPEPTGLRYCMNSVALVFAARA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWL6</accession>
    <name>A0A2S9GWL6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DNA polymerase III chi subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3250</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000016">
        <property type="protein sequence ID" value="PRC92115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92115">
        <property type="protein sequence ID" value="PRC92115"/>
        <property type="gene ID" value="S2091_3250"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007459">
        <property type="entry name" value="DNA_pol3_chi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036768">
        <property type="entry name" value="PolIII_chi_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38767">
        <property type="entry name" value="PTHR38767"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04364">
        <property type="entry name" value="DNA_pol3_chi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102400">
        <property type="entry name" value="SSF102400"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="145" mass="16763" checksum="4374E9C488A983A3" modified="2018-07-18" version="1">MTRIDFHSNVSNQLDYACRLVRKALAAKCHLVVRHQNKEQLAQFNQLLWEFSATDFLPHVAIHEGPHPLTQHTPVLLSLDAESDIPESTHMQILLNLSDQVPTDFARFERLIEIVPQAAQATQAGRERYRFYQQQGYQLNHIHAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWM4</accession>
    <name>A0A2S9GWM4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3257</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000016">
        <property type="protein sequence ID" value="PRC92122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92122">
        <property type="protein sequence ID" value="PRC92122"/>
        <property type="gene ID" value="S2091_3257"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="96"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="100"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="145" mass="17299" checksum="D51CB3246A2EC93B" modified="2018-07-18" version="1">MTLIAAPLLAHAQVSINIGQPGFYGQIEIGNAPPPQVVYSAPVIVQAAPTQEAYPPMYLRVPEEHHRDWRRYCHEYNACNRQVYFVTNDWYNNSYAPHYAREHGHGHDHEYEERERERDRDHERDHGHDRDHEHERDHERDNERN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXC4</accession>
    <name>A0A2S9GXC4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative hydrolases or acyltransferases (Alpha/beta hydrolase superfamily)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3033</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92374">
        <property type="protein sequence ID" value="PRC92374"/>
        <property type="gene ID" value="S2091_3033"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000639">
        <property type="entry name" value="Epox_hydrolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00412">
        <property type="entry name" value="EPOXHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="66"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="316" mass="35224" checksum="2E0DF154839D86DD" modified="2018-07-18" version="1">MRYIKLLLVLVFAAVLGLYYFIYVMSAQATSFFVNFERNSAKLTRHEIVLPDGFHYAYLEGGHGEPLMLLHGFGADKDNFTRVAQRLTPQYHVIIPDLLGFGESSHPNSSDNVTDFTARAQAERMRALAHVLGIQTLHLGGNSMGGQIALAYAAAHPTEVMSLWLLDPAGVWSAPESELAKLIGKQKHNPLLVSNEDDFAQAFNFSMNKPPYIPRPILNVLAQTSIKNSALSEKIFNQITSDSIEARVTGLKTPTLIVWGDQDRVLNVATAEILYKLMPKSRVVIMPNIGHLPMIEDPQQSAEDYLFFRFKLQAPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXE8</accession>
    <name>A0A2S9GXE8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative hydrolase of the alpha/beta-hydrolase fold</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2772</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92397">
        <property type="protein sequence ID" value="PRC92397"/>
        <property type="gene ID" value="S2091_2772"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012020">
        <property type="entry name" value="ABHD4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005211">
        <property type="entry name" value="Ab_hydro_YheT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="2">
        <location>
            <begin position="57"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="318" mass="35522" checksum="AABB8056B971F672" modified="2018-07-18" version="1">MQTNYVSPAWMSNGHLQTIIPAKLLTIPTVSYRRERWNSPDNDFIDLDFVDAVADAPLVVLFHGLEGNSNSHYARALMAEVKSRGWAGVVVHFRGCSGEMNQGPRFYHSGDSTEINWVLRRIHQQHPQRSLFVCGVSLGGNALLRWLGESQNQASFVQAACAVSAPLDLTQGGVALGSGFNMLYTTVFLRTLKPKCLAKLAQYPDLFNRQTMLDAKNLYEFDNVVTAPLHGYKNTEDYWNRASAKHILGDITLPTLVLNAKNDPFLPGRYLPENAASCVTLEYPQHGGHVGFAGGSWRADNMWLPKRVLHFFEQYQPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXH4</accession>
    <name>A0A2S9GXH4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative Na+/dicarboxylate symporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_2788</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92413">
        <property type="protein sequence ID" value="PRC92413"/>
        <property type="gene ID" value="S2091_2788"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015293">
        <property type="term" value="F:symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3860.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001991">
        <property type="entry name" value="Na-dicarboxylate_symporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036458">
        <property type="entry name" value="Na:dicarbo_symporter_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42865">
        <property type="entry name" value="PTHR42865"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00375">
        <property type="entry name" value="SDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118215">
        <property type="entry name" value="SSF118215"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="52"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="86"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="133"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="186"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="230"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="273"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="307"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="349"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="378"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="402"/>
            <end position="426"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC92413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="472" mass="50538" checksum="5DA8A4906F6482D0" modified="2018-07-18" version="1">MNDAQQPALFQGVFFEKFLAITHYQTLISIAVLLLCFWGLNQLQNKKIDFSIRMLVGLVAGALLGLGIQALVGFPAEATTWMKETAIWYGLVGRAFVAFIRMLVIPLIFVSIVKVILDFSGKRDLPQIAVRGIFWLLFTTAIACVLGIILANLFHLGAGVSSAPTEKVNEYTNLVDTFIRLIPSNIIVAMNGENIVGLVIFSALIGIAANRMEHKNPEAIGVFKKLMQALYKIVMSIAMTIIKYMPYAVVALLARTIISNGIPAIIEVSSFVAAIYIATAVMVSIHIVIIVLHGVSPLMYVKKALGTWLLAFTSRSSVGTLPMTIATLTTRMGVNNGTANLVGSLGSTIGMNGCAGFFPAMIVVMVAHMVGIEVNTQFYIMMLIVITIGSIGIAGIPGTATVAATIALSGMGMGEHFALIGMVLAIDPIIDMARTLTNVSGTMTAAIATDREMGTMDMAVFNDPHATLDNDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXX2</accession>
    <name>A0A2S9GXX2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">2-keto-3-deoxy-6-phosphogluconate aldolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2613</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the KHG/KDPG aldolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92558">
        <property type="protein sequence ID" value="PRC92558"/>
        <property type="gene ID" value="S2091_2613"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00452">
        <property type="entry name" value="KDPG_aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000887">
        <property type="entry name" value="Aldlse_KDPG_KHG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30246">
        <property type="entry name" value="PTHR30246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01081">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="212" mass="22683" checksum="DE24C7637A407F23" modified="2018-07-18" version="1">MTNPTLISQHFLHYLTPIPLVAILRGIQTHECEAVIDVLYESGFRCIEIPLNSPNALQSIELLAKNLPNDCLLGAGTVLSVESVQHVADAGGHLIVMPHCDIELITESHRRKLLSVPGVATISEAFAALKHGASALKLFPSESVAPSVLKNWRTVLPKETICLPVGGISPDHMKAYFEAGASGFGLGAALYQAGMTVDQVRNNAKNFVAALK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXZ0</accession>
    <name>A0A2S9GXZ0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Glycosyl hydrolases family 31</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_2625</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 31 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92570">
        <property type="protein sequence ID" value="PRC92570"/>
        <property type="gene ID" value="S2091_2625"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.1060">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032513">
        <property type="entry name" value="AGL_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033403">
        <property type="entry name" value="DUF5110"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000421">
        <property type="entry name" value="FA58C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013222">
        <property type="entry name" value="Glyco_hyd_98_carb-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000322">
        <property type="entry name" value="Glyco_hydro_31"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038637">
        <property type="entry name" value="NPCBM_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16338">
        <property type="entry name" value="DUF4968"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17137">
        <property type="entry name" value="DUF5110"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00754">
        <property type="entry name" value="F5_F8_type_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01055">
        <property type="entry name" value="Glyco_hydro_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08305">
        <property type="entry name" value="NPCBM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00776">
        <property type="entry name" value="NPCBM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="SSF49785"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="SSF74650"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015735386" evidence="3">
        <location>
            <begin position="23"/>
            <end position="1103"/>
        </location>
    </feature>
    <feature type="domain" description="NPCBM" evidence="4">
        <location>
            <begin position="953"/>
            <end position="1092"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC92570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="1103" mass="122257" checksum="DFE1540C19D69301" modified="2018-07-18" version="1">MHSSIRKTLVATLLLAAFSAQATPIGNLKKISHSTASQIQLTTDSGNLVQISLLRPDMFRVWAGLGGHLTDSGDKAAPIVLPHDYPQVDYQLSDHADYQLLQTSGMALRIYKKPLRLALYKADNKTQLWQETQSLELSEKGSYQSLSSSPDEVFFGGGQQNGAYAFKGKMLEVSYSGGWEEGDRPSPAPFYMSNKGYGVLRNTWSNGSYDFRSNDYITASHLENRFDAYYFVGDSIKEVLAAYTDLTGRARILPRWAYEYGDADCYNDGDNVKKPGTVPNGWSDGPTGTTPDVIQSVAAKYRQYDMPGGWILPNDGYGCGYTKLPEVVAGLAPLGFHTGLWTESGVDKIANEVGKAGTRAQKLDVAWTGQGYQFSLDANMAAAQGILDNSDARPFVWTVMGWAGTQRYAVTWTGDQSGSWDYIRWHIPTLIGSGLSGQAYATGDVDGIFGGSPETYTRDLQWKTFTPVLMGMSGWSKNERKHPWWFDEPYRSINRTYLKLKMRLMPYMYTYAKIAEDSGAPIVRGLMWDHPNDPNANSEAYKYQFFLGKDFLVAPVFRSQAASKGWRKGIYLPQGEWIDYWDGRVVDAGAEGKVIDYQVSLDKLPVLVRAGAILPMYPSALYDGQVPKDVLTLDIYPHEQSEFTLYEDDGITRTYQQGSFSQQKINVDAKAGNIQVNVAAVQGSYQGMEAQRVYQLQVHTRVKPDAVRLQDQALSEFKTRAEFDQAESGWFFDEHEKYGLLYVKTAKVSVNQAYQFNVVITAPQAITTGYPAAPELGNAIPADNIIVLNRPAEEPGHPLENAFDGKPDTWFRTLRDQSQKTGPHEFTLALGERRMINGFEIAPRNDKNWMYGQAREVEVYLGDNNGEWGAPVFKGELKKLETRQKVEFPAKAGRLFRFRILSTWDQDDEGNAADPMVVATTVNAAYNAFNTVAVAPITISEFSVLEYPVPDRAKLQLYLSDVASKQVGVSSDKADTNRPSNADNLMQMNGLRFHKGLGVTGQSDIEYSLSGDWQTFRADVGIDDACRNAGGLQFQVWGDDKLLFNSGLIVAPAVVKPELDIRGISKLSLKTIVATKTAGKVCANWANASVLGFKGDSVAKFGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GY01</accession>
    <name>A0A2S9GY01_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2648</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92593">
        <property type="protein sequence ID" value="PRC92593"/>
        <property type="gene ID" value="S2091_2648"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16331">
        <property type="entry name" value="YjgA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.60.30">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023153">
        <property type="entry name" value="PSPTO4464-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006839">
        <property type="entry name" value="Ribosome-assoc_YjgA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38101">
        <property type="entry name" value="PTHR38101"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04751">
        <property type="entry name" value="DUF615"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016183">
        <property type="entry name" value="UCP016183"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158710">
        <property type="entry name" value="SSF158710"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="182"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="204" mass="23745" checksum="8B26F725A093D3BE" modified="2018-07-18" version="1">MPNPNRGSCGFQSTEFEQEYERPSKSALKREMTALQKLGQELIDQPRDRVKRVPMPEDVRDAILECQLIKDHEGRRRQLQFVGKKMRTLDAEELATIQRTIDSWKGASKSETATMHSFEKKRDKLLADDKALTELLEQHPHLEAQHLRTLIRNARKEQAENKPPKAYREIFQILKQLHADSKKAAKELEDDHGDDEDEDESDPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GY92</accession>
    <name>A0A2S9GY92_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2736</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92681">
        <property type="protein sequence ID" value="PRC92681"/>
        <property type="gene ID" value="S2091_2736"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="1188" mass="121752" checksum="86520793FF1D1626" modified="2018-07-18" version="1">MPTIVNYRDVILQSHSPRVLSDNTLSIAEKPALILQYATILSQQTSMDAQATAYGLTALQATYDASIATLTAHLATLTNPVAWNNLTNTTNLPLTGTYLRSLISATVVAEANIATAISNSTLSSLSTIASSNILTPSGRNEVNIDMYAILQGQASLDSQAAQMGVSHTAYDAAISTLSTYLATLGYPSGAAWTSATGNIAIVGSTFIADFQAVYAAQQLLINATTGAVAALPVGLGNMINNSGPVPGDMTGYVTGFNTTGLTPILAPSVDPNRPTGQGGITVTSSGTPASGTYHLLQPNAGVNMPVVVGQLYELSSYIAAFNCTSNVYLNWLNSAGTIIGSAGGTQLVSNGSSTTTGILGNWQRSYLLATAPVGTASAAIYVETVYTGAATPKTCASMLYFAQAVTGQTALSAWVDGNTANWSSNVIGAPAVTASIVSAQTQANLGVTNASTANTQLASIASLNVLAMQDKPVVVQDFQAILNDQVGIAAQATAVGVSSTAYYTAINALNAYLGSLSPAWNDATQNTTIVGTTFDANFAAVYTQRQIVLNATAAAVAALPAGLGNMINNSGPVPGDFTGYVLDNNTTGLTPIIAASPDPYRPTGQGGVYVEFAGTPAAATYTLLHPNAAINIPVAALQTYEFSVYLGAYRTSAYVLIQWLNSSGAIISGAQGNTLTDVTSSGPLSGWARSFVIAQAPSGAVTANIGVLSLYTGEANPYTFCSMWYFAAAKVGQTLPSAWSDGNTANWATNVIGAAAINASILAAQNQIAAIGSTNVLSMGEKTSVIVDWNSIVNTQAGIDAQAAAVGVSHVAYDAAVSALSTYLGAMSPAWNDTTQNTTIVGATFIANWQAVYVAEQALLNAIGSATANAGGGNLLMNSDFGNGVNGYNAYNNGATPIATITAQSAGGAITPGTYVQVICNGAGSTSFGTWFASSLFGGFFANTSYVISFYAVSNGSVMGAPMNLGWNHSPATATWLLNPPLNGNWQRYAVLVNFGANTVDTGMFLTSTNMPAIGNVIDFSNLMVQVGSVPTAWQPCPVSAMNPITSTNSGSMVGAAAVTTTHLIPNAATYPLSAFTAAGTGSLTAATTVQTLTYTSTGAVTNIQFSLGLIQGAGVATYPTISITRNGTTIYSWETQTSTAGEWSFSAGIADTPLAGSVTYNLVLTPVSSSFPEQAFNRLLLAIEFRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYC1</accession>
    <name>A0A2S9GYC1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2711</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92656">
        <property type="protein sequence ID" value="PRC92656"/>
        <property type="gene ID" value="S2091_2711"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="82" mass="9416" checksum="7D0CE50643F72AC4" modified="2018-07-18" version="1">MTCPCFNPLDGRIQRGKECCDIKELAIMPLAHLKIATKAMPKSEWEELKPKVVARRKLIREEREVRIKSARDQAITTLKGVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYP7</accession>
    <name>A0A2S9GYP7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2563</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92833">
        <property type="protein sequence ID" value="PRC92833"/>
        <property type="gene ID" value="S2091_2563"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008318">
        <property type="entry name" value="UCP030820"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06073">
        <property type="entry name" value="DUF934"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF030820">
        <property type="entry name" value="UCP030820"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="178" mass="20126" checksum="A3F31FBA53FF726C" modified="2018-07-18" version="1">MSELKINYEIIKDRQVVSDSWQVVRLAEDQTAETVTVPEGPVIVPLAVWQAQHETLAARSNVGVWLASSERAEELKNEVNALPVIAVDFPKFSDGRGYSIAYNLRSRLGYQGELRAIGDVLRDQLFYMQRVGFNAFATRPDRNIHDALKGLTDFSESYQTSIDQKSPLFRRIERPAAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYV6</accession>
    <name>A0A2S9GYV6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">/NonD: hydrolase CocE/NonD family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2319</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92902">
        <property type="protein sequence ID" value="PRC92902"/>
        <property type="gene ID" value="S2091_2319"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008239">
        <property type="term" value="F:dipeptidyl-peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005674">
        <property type="entry name" value="CocE/Ser_esterase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000383">
        <property type="entry name" value="Xaa-Pro-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013736">
        <property type="entry name" value="Xaa-Pro_dipept_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02129">
        <property type="entry name" value="Peptidase_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08530">
        <property type="entry name" value="PepX_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00939">
        <property type="entry name" value="PepX_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="SSF49785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00976">
        <property type="entry name" value="NonD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015478980" evidence="1">
        <location>
            <begin position="28"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="domain" description="PepX_C" evidence="2">
        <location>
            <begin position="379"/>
            <end position="639"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="644" mass="71416" checksum="AB7EE3C9B67F44B3" modified="2018-07-18" version="1">MKQSSSKCKAQVLLSIVLAVSTTFTYAQSNQSKLTAISPDDVASYDFVRPEADYVKRVQMIPMRDGTKLYTVIVMKKNVTKGPILLSRTPYDAKSSTTRTRSQLITEILPAMDAEFVADNYIRVYQDIRGTHNSEGDFVMARPIVGPLNNTGVDEATDAYDTIDWLVKNVPESNGKVGTIGSSYLGFTTLNSLINPHPALKAAVPQSPMVDTWIGDDDFHNGAFRVPTMDFIVDQSTDKANAGAQVGFGVGDDYTRYLESGSAGDYARKWGIDLFPNMQKILQNPAYTEFWSLQAVDKWLAARPLTVPTMLVVGQWDQEDSYGAPAVYKAIKPKDKNNDMVTLVIGPWRHSGANHYGYGLGALTFTGDTALEFRVNYLKPFLDHYLKGASDPHTPHVLTYATGLNRWDISPKWPMGTMTPLYLGQHFSASFKADNSSGHNDYVSDPSKPVPFLPRPVNLGDETSWKSWLVHDQRFVSDRPDVLVYKTQALDKPIHIMGEPLVDLFAATSGTDSDWVVKLIDVFPNVSPEPAEQGSKPSMAGFELPIGIEIFRGRYVHGFNKPQSLTAGKIEEYKFGLPNVDHVFLPGHKIMIQVQSSLFPLYDRNPQTYVDNIFNAKAEDYKSATESVYYGGENASSVLLPLVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYX5</accession>
    <name>A0A2S9GYX5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2327</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92910">
        <property type="protein sequence ID" value="PRC92910"/>
        <property type="gene ID" value="S2091_2327"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="72" mass="7963" checksum="ECD41FA957AF3474" modified="2018-07-18" version="1">MPKLLDYLNHLDQNADARTTHEQNPQQAMTEFGLSTEEQQVVQSGDKEQVAKVLGISSAQLPSIEVSMFSAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZ30</accession>
    <name>A0A2S9GZ30_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DNA polymerase III subunit gamma/tau</fullName>
            <ecNumber evidence="4">2.7.7.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">dnaX</name>
        <name evidence="6" type="ORF">S2091_2375</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="4">DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the DnaX/STICHEL family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="4"/>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92958">
        <property type="protein sequence ID" value="PRC92958"/>
        <property type="gene ID" value="S2091_2375"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009360">
        <property type="term" value="C:DNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18137">
        <property type="entry name" value="HLD_clamp_pol_III_gamma_tau"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001270">
        <property type="entry name" value="ClpA/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008921">
        <property type="entry name" value="DNA_pol3_clamp-load_cplx_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022754">
        <property type="entry name" value="DNA_pol_III_gamma-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012763">
        <property type="entry name" value="DNA_pol_III_sug/sutau_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045085">
        <property type="entry name" value="HLD_clamp_pol_III_gamma_tau"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038249">
        <property type="entry name" value="PolIII_tau_V_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12169">
        <property type="entry name" value="DNA_pol3_gamma3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00300">
        <property type="entry name" value="CLPPROTEASEA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48019">
        <property type="entry name" value="SSF48019"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02397">
        <property type="entry name" value="dnaX_nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0235">DNA replication</keyword>
    <keyword evidence="4" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AAA" evidence="5">
        <location>
            <begin position="37"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU364063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC92958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="657" mass="69903" checksum="FAA6DFB8A13F7C41" modified="2018-07-18" version="1">MSYQVLARKYRPKSFQTLVGQEHVVRALTHALEQQRLHHAYLFTGTRGVGKTTLSRILAKSLNCETGITANPCGVCDACVAIDAGRFVDYIEMDAASNRGVDEMAQLLEQAVYAPSNARFKVYMIDEVHMLTNHAFNSMLKTLEEPPAHVKFILATTDPQKIPVTVLSRCLQFNLKQMPLTAIVGHLENILGQETIQFELPALRLLAQGAQGSMRDALSLTDQAIAYAAGTVSLEAVQGMLGALDQTYLIKICDALAEQDGAGLLAVADQMATRSLSYKAALQDLASLLHQLSIAQLVPAAIPNDLPERAEILRLASLFDAEQIQLFYQIAVHGRNELSLAPDEYAGFSMTLLRMLAFRPVTGEAAAMLSAPAAKSSSNVTSNPASAAMRSAVATPAANPSRPAPAPVAMPAQVQAQARTSTGVEGVAPAKINPAMAALAALNSRRGAGRNVEPASATPPAPLPWEELDSAAPVTVLAEKKTELNAEAEFNSEIKTEPVRAVAPATSLPAAPILPPAPVIQGVSLLSGGEWDGNWPRLSAGLSLRGVAQQLAQQSELLSCEVTPHVITFGLRVPLETLLTAGSADKLASVLSEHFTVPVKLTTEIGQVQRTAHAEAIVERAVRQDAAEGAIKNDLLVQGLMREFGATIVPNTIKPIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZ67</accession>
    <name>A0A2S9GZ67_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Phosphate transport system permease protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">S2091_2111</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell inner membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93025">
        <property type="protein sequence ID" value="PRC93025"/>
        <property type="gene ID" value="S2091_2111"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005315">
        <property type="term" value="F:inorganic phosphate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006817">
        <property type="term" value="P:phosphate ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011864">
        <property type="entry name" value="Phosphate_PstC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02138">
        <property type="entry name" value="phosphate_pstC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0592">Phosphate transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="49"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="96"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="139"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="187"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="252"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="313"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="11">
        <location>
            <begin position="102"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PRC93025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="345" mass="36878" checksum="2114F79EA5710152" modified="2018-07-18" version="1">MNSSPDMTSDSINQISTETSVKSSVETSQSKMNLPMRSHKLGDFIFHKITLSFALSVLLVLLGIIVSLLIGAWPALHEFGPAFITTIEWDPVNEKYGALIAIVGTLATSFIALLIAFPISFGIALFLTEICPAWLKRPLGTAVELLAGVPSIIYGMWGLFIFAPFFAKYIQPVLAATLGQLPGIGKLFQGPMIGIGILAAGIILAIMIIPFIASVMRDVFEVVPHILKESAYGLGCTKWEVVRKVVLPYTKIGVVGGVMLGLGRALGETMAITFLIGNANRLSWSLFAAGNSIASTLANEFAEADTPLHVSSLYALGLILFVITLIVLSAAKLMLLGLKKSEGLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZ96</accession>
    <name>A0A2S9GZ96_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SsrA-binding protein</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Small protein B</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">smpB</name>
        <name evidence="5" type="ORF">S2091_2141</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="3">The tmRNA-SmpB complex associates with stalled 70S ribosomes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the SmpB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93055">
        <property type="protein sequence ID" value="PRC93055"/>
        <property type="gene ID" value="S2091_2141"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070929">
        <property type="term" value="P:trans-translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd09294">
        <property type="entry name" value="SmpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00023">
        <property type="entry name" value="SmpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023620">
        <property type="entry name" value="SmpB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000037">
        <property type="entry name" value="SsrA-bd_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020081">
        <property type="entry name" value="SsrA-bd_prot_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30308">
        <property type="entry name" value="PTHR30308"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01668">
        <property type="entry name" value="SmpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74982">
        <property type="entry name" value="SSF74982"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00086">
        <property type="entry name" value="smpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01317">
        <property type="entry name" value="SSRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0694">RNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="125"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="125"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC93055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="149" mass="17259" checksum="0DD04C9B85EB21FB" modified="2018-07-18" version="1">MSIADNKKAFHDYFIEEQFEAGVVLQGWEVKAIRAGRVQLKEAYVIVKNDEIFLFGAHIGALPTASTHISPEALRTRKLLLNKSEINKLVIKVERAGYTLVPVNMHFKGGRIKLQIGLAKGKKQYDKRDTEKDRDWQREQQQMMKIHRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZC7</accession>
    <name>A0A2S9GZC7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative phage head-tail adaptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2170</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93084">
        <property type="protein sequence ID" value="PRC93084"/>
        <property type="gene ID" value="S2091_2170"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008767">
        <property type="entry name" value="Phage_SPP1_head-tail_adaptor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038666">
        <property type="entry name" value="SSP1_head-tail_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05521">
        <property type="entry name" value="Phage_H_T_join"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01563">
        <property type="entry name" value="gp16_SPP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="106" mass="11626" checksum="2314987624F3B3E2" modified="2018-07-18" version="1">MNSGQLNRRITIQAASTKQDALGQPIDGWSEVATVWAGITDINGREFIAAAAVQNTVQTKIIIRYRAGITPAMRVLHKDSIYNIEAVLGQDNVWLNLMCSKEVNNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZD5</accession>
    <name>A0A2S9GZD5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2153</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93067">
        <property type="protein sequence ID" value="PRC93067"/>
        <property type="gene ID" value="S2091_2153"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="87" mass="9389" checksum="D19787E24BE6740D" modified="2018-07-18" version="1">MTTTDKAVVIYCDPGCDRSGYALSLARHYKKTAIIGGASCLEFSEFPSNALVLTSDDTIPSAIPFITAVNDMMKCATGHIKIKERES</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZH2</accession>
    <name>A0A2S9GZH2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">O-antigen ligase like membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_2433</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC93016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93016">
        <property type="protein sequence ID" value="PRC93016"/>
        <property type="gene ID" value="S2091_2433"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007016">
        <property type="entry name" value="O-antigen_ligase-related"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04932">
        <property type="entry name" value="Wzy_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="2 3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="12"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="33"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="63"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="96"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="120"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="151"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="175"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="198"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="222"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="323"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="362"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="386"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC93016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="414" mass="47179" checksum="2EA12C152C07C23D" modified="2018-07-18" version="1">MLNKLNRYRGSAPLVIAIFFFAFGVAFQKIDNISFYLLVLFFLIIVFLQSEKDRKFSLGICREYWPIILSMCGIVFAIGINQLSTGNFSIRIFDKPSRLALFVCVFWLFLTIPSNKFKQVKWGFILGSIICTIQIALLTSDHISRPMVNDIEIIALLSTFSFLSIGWNSANSKTALFFQITAGLAGLYSVYISQTRGVWMALPIFAVIILSTLCANIITKKIFFTFIFLATIFTGIFSTTNIVRDRIKQGSQDINQYLEKSNLDTSIGTRFQLWEGSWIIFKENPIFGIGREDKNFSSSLKKLAERKLVTPVLFLQPHSHNEFLYNMMSLGIFGLIGLSITYLTPLYYFLKYIRHPDNEIRVATAMGLALCLGFMIYGLVDVLFMYKGATIFYSISIAFFLAQIIKRKNLISHC</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZS9</accession>
    <name>A0A2S9GZS9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NAD-dependent aldehyde dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2212</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93126">
        <property type="protein sequence ID" value="PRC93126"/>
        <property type="gene ID" value="S2091_2212"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016620">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldedh" evidence="2">
        <location>
            <begin position="4"/>
            <end position="456"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="462" mass="50595" checksum="8944C4B96102A946" modified="2018-07-18" version="1">MLKDISTISPIDGSIVVQRRCATSSEIQAVLAKATFAQRKWRQLSLADRCQHVQNAVAELVTARAGIAEEITRQMGRPIRYTPSEINAFQDCALHLISIAPAALADVMPAPVSGMQRLMRREPHGIVFIIAPWNFPLLTCVNSLITALLAGNTVVLRHSSQTPLVSERLVEAFHDAGVPDGVLQYVHTTHADTRLIMKAPEIDYLCFIGNSSSALMVEQIELGRCIGLGLELSGVDPTYIRADADLEKTVDAVVEGAMFNSGQSCSGVQRVYVHASRYQEFLDRAVVEVEKYVLGNPLNASTTLGPLVRLSAATTVREIVGQSMSMGAKCLIDIHKFALDNINTPYMAPQILANADHQMKIMQEDCFGPVFGVMPVQTDEQAIELMNDSHYGLSASVFTQDITAAMQIGAQVQTGTWLMNRCDYHDPALAWSGVKQSGRGVSSSYLGFVQLTRVKSYHMRSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZZ6</accession>
    <name>A0A2S9GZZ6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Enoyl-(Acyl carrier protein) reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2047</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93309">
        <property type="protein sequence ID" value="PRC93309"/>
        <property type="gene ID" value="S2091_2047"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="199" mass="21060" checksum="C6942D608E9CF1D9" modified="2018-07-18" version="1">MKIVHIGATGTLGSAVVTELAPRHEIIQVGHQRGQLQVDITNSDSIKTLFERIGKVDAIIATTGNLHFGPLTQMTAEQFRIGLNSKLLGQVDLALIGQHYLNDAGSITLTSGIVANQPIRLGANASAVNSAIEGFVLGAAIELARGIRINVVSPTILEESMGIYGDFFAGFEAVPARRAALAFRRSVEGAQTGQVYQVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H000</accession>
    <name>A0A2S9H000_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">RsmB: ribosomal RNA small subunit methyltransferase B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_2053</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93315">
        <property type="protein sequence ID" value="PRC93315"/>
        <property type="gene ID" value="S2091_2053"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008649">
        <property type="term" value="F:rRNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.940.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001678">
        <property type="entry name" value="MeTrfase_RsmB/NOP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035926">
        <property type="entry name" value="NusB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023267">
        <property type="entry name" value="RCMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004573">
        <property type="entry name" value="rRNA_ssu_MeTfrase_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22807">
        <property type="entry name" value="PTHR22807"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01189">
        <property type="entry name" value="Methyltr_RsmB-F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR02008">
        <property type="entry name" value="RCMTFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48013">
        <property type="entry name" value="SSF48013"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00563">
        <property type="entry name" value="rsmB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51686">
        <property type="entry name" value="SAM_MT_RSMB_NOP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4 6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 4 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SAM_MT_RSMB_NOP" evidence="5">
        <location>
            <begin position="193"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="4">
        <location>
            <begin position="281"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4">
        <location>
            <position position="400"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="303"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="329"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="347"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC93315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="450" mass="49464" checksum="B8F44CAD9289A06B" modified="2018-07-18" version="1">MTKLPKPPKFPQAAPLLSDLDLKSDSLSYSLIGASQAISLVLNGLALPQALSKIFTSSNVAPANRGAIQDLSYRTMRQVGRVDALISAMTTKAPEPALLYSLLCCCLALIVEEDKSVHPYAEFTVVDQAVNAAAAHPDIAHAKNMVNALLRRFLRERKELLDTVMKLPPARWNYPQWWIDSCKTAYPNDWQAILTAGNLTPPLTLRINQHKTSMSTYLSLLQENGMPAKSIGDFAVRLEQALPVQQIPGFMDGLVSVQDAAAQLAAPLLDLQDGMRVLDACAAPGGKTGHLLETANINLLALDSDPKRVTRITENLDRLQLKAKLIVGDATKTDWWDGQQFDRVIADLPCTASGIVRRHPDIRWLRRKVDSAQLATLSARILDNLWMMTKPNGKLLLVTCSVWPQESEAQAAAFAHRHQAKRLTAPGQMLPTATADSDHDGLFYALFQKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H096</accession>
    <name>A0A2S9H096_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Gluconolactonase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1792</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93405">
        <property type="protein sequence ID" value="PRC93405"/>
        <property type="gene ID" value="S2091_1792"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013658">
        <property type="entry name" value="SGL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005511">
        <property type="entry name" value="SMP-30"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08450">
        <property type="entry name" value="SGL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01790">
        <property type="entry name" value="SMP30FAMILY"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SGL" evidence="1">
        <location>
            <begin position="23"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="322" mass="35159" checksum="3CEAD392E628C22F" modified="2018-07-18" version="1">MFAQSSLTPELTMSVVHAQKNILGEGLLWHPADQRWWWTDIESATIHAWSGETGLRCDFQPGGRVGSMAHSRSGRILLGMAKWVCTAELPDLAAVPLVAVDPAEPRTRINDGRTDRSGNFVFGTMNEATDKRAIASFYHYSHLHGLRRLALPAVAVANSICFSPDGKTMYFCDTPTRCIMQCDYDSDSAQVNNIRLFSKVADADGVAAFPDGSVIDRHGCLWNAQWGASQIAQYAPDGRLIRRIAVPVKNPTCPAFGGSNLDMLMVTSSTQEMSNAELIHMPDAGSLFGITLPEPIGIAETLFDDMPDVSVAVEIRMNTKQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0A0</accession>
    <name>A0A2S9H0A0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Dehydrogenases with different specificities (Related to short-chain alcohol dehydrogenases)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1796</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93409">
        <property type="protein sequence ID" value="PRC93409"/>
        <property type="gene ID" value="S2091_1796"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="257" mass="27694" checksum="407B373CA5B46205" modified="2018-07-18" version="1">MTQRLAGKVAIVTGSTLGIGRAIARLFVDQGASVVFNSHRYDDAAAQMCDELGKEHALFVQADVADTYAMQQLASTSVARFGKVDVLINNAGMDVFSDPLAMTPDQWQRCFSVDLEGAWNASRSVLPSMLEQGSGSIVNIASVHGHKIIPGCFPYPIAKHALIGLTRSLGIEYAARGIRVNSISPGLIMTDNVKTWLANCPDPEAEQARQAALLPCKRIGTPEEVAYTALFLASDEARFINATDILIDGGRSQLYHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0B0</accession>
    <name>A0A2S9H0B0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1806</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93419">
        <property type="protein sequence ID" value="PRC93419"/>
        <property type="gene ID" value="S2091_1806"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015716030" evidence="1">
        <location>
            <begin position="31"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="124" mass="13496" checksum="6A6031BF77FC086D" modified="2018-07-18" version="1">MIKNSSRILAKSLLAVVLASSIVAPTLAFAEKAYLEITLKVDPKDRAAAGAVYAKYKQPFLTQISGAESKELLIRDDDVQVLHGFASRQQAEAYLSSDLFNKDVVASLKPLLKAAPEVRIYTSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0B5</accession>
    <name>A0A2S9H0B5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cation/multidrug efflux pump</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2044</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93306">
        <property type="protein sequence ID" value="PRC93306"/>
        <property type="gene ID" value="S2091_2044"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2090.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027463">
        <property type="entry name" value="AcrB_DN_DC_subdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001036">
        <property type="entry name" value="Acrflvin-R"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32063">
        <property type="entry name" value="PTHR32063"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00873">
        <property type="entry name" value="ACR_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00702">
        <property type="entry name" value="ACRIFLAVINRP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82714">
        <property type="entry name" value="SSF82714"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="354"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="385"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="417"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="451"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="497"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="554"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="886"/>
            <end position="905"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="938"/>
            <end position="959"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="987"/>
            <end position="1006"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1012"/>
            <end position="1036"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="1044" mass="114956" checksum="0F3148AFB41487AF" modified="2018-07-18" version="1">MSGHEQRSEQMESKSKIKSGFNLSRWALEHIPLTRYLMVALLIGGIFSYGQLGQDEDPPFTFRAMVVRAVWPGATALQMAEQVTDKLEKKLQETPYIDKIRSYSKPGETTIILQLRESTPPKETPQAWYQVRKKMADIQGTLPPGVIGPFFNDEFGDTYGSIFALSGDGFNYAQVKEYADYVRQELLRIPSISKVELFGAQDERVMIEFSQKKFAQLGITVDAVVAQLNAQNAVDSTGVLVTSTDNLQVRVTGALKTAKDFEDLELRANGTPFRLGDFAIVKREYQDPPQDKMRFNGREVIGLGVSMEKGGNIILLGQNLEKTVAQIKAKLPIGISLERVSNQPKIVADSVNEFIRALMEAVVIVLAVSFLALGLHTKPLRLDIWPGLVVGLSIPLVLAVTFLFMRILDIDLHKISLGALIIALGLLVDDAIIAVEMMVRKMEEGFSRFDAATFAYTSTAIPMLTGTLITAAGFLPIGLAKSAAGEYTFSMFSVNALALLISWLVAVIFTPYLGYLLLKVKPVSSHGAGHEVFDSPFFNRFRSLVNWCVEWRKTTIAITLGVFALGLFGFKFIEQQFFPDSSRPELMVEMWLPEGSSFKATEAQVKKFEALVRKEAGVESITSYVGTGSPRFVLTLDQIFPQSNVAQIVVLPVDLNAREALRLKIGEYFKTDFPEVRGRVRLLPNGPPVPYPVQFRVMGLEVQTVRKIADQVKEIMRVNPNTLGVNDNWNESVKVLRLDLEQDKLRALGISSQTVMRTANTLLSGTTVGQFREDNKLIDIVMRQPAEERSTIEALNQANIPVAGGRTVPLSQVARVHMVWEPGVVWREGREWAITVQSDVIDGIQGATVSSQIDPKLEAIRATLPAGYVIELAGAAADSSKAQDSIAANVPLVIFIIFTLLMLQLQSFSRTVLVFLTGPLGLAGASMALLILHRPMGFVAQLGVIALFGMIIRNSVILIDQIEQDIVAGSPPWTAIVESAVRRFRPIILTAAAAVLAMIPLSRSVFWGPMAVVIMGGLIVATALTLLFLPALYATWFKVKPVQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0F2</accession>
    <name>A0A2S9H0F2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Response regulator receiver domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1851</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93464">
        <property type="protein sequence ID" value="PRC93464"/>
        <property type="gene ID" value="S2091_1851"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="7"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="137" mass="15761" checksum="5F014B0FC76BE9B1" modified="2018-07-18" version="1">MKFANKPLLVIEDDQVDVMTIKRALKEIHVANPVIHMENGEDAIAYLRDASKEKPCIILLDLNMPVMNGLEFLEVVKHDDELRRFPVIVLTTSEEQQDKVNSFNLGVAGYMAKPVNYRQFVEVMRSIDLYWTISELP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0M2</accession>
    <name>A0A2S9H0M2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Exopolysaccharide/PEP-CTERM locus tyrosine autokinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1916</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93529">
        <property type="protein sequence ID" value="PRC93529"/>
        <property type="gene ID" value="S2091_1916"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025669">
        <property type="entry name" value="AAA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13614">
        <property type="entry name" value="AAA_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AAA_31" evidence="1">
        <location>
            <begin position="117"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="307" mass="33739" checksum="C5F730F9A21A4079" modified="2018-07-18" version="1">MSIIEKAINRLDHGKAVAPDTVQLEPKHLAEPEKEPTPAVTTTTIPEAAAPSQVHFLGGKRTSRMIEIDLAQLHQLGMVTPDAERSVIAEEFRRIKRPLIEKTFNANAAALKHGNLIMVASSLPGEGKTFCAVNLAISIAMELDHTVLLVDADVARPSVPRYLSVVQNQDASTIGLMDVLLDDKLDLADAMLRTNIDTLTILRAGRSHKRATELLASQAMSRLLDEISSRYPERIVIFDSPPLLLSTEARVLASQMGQIVLVVEAESTTQYAVKEVLRQLQSQKNITLLFNKVKAFAGEEYYGSYYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0V4</accession>
    <name>A0A2S9H0V4_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 15">NAD(P) transhydrogenase subunit beta</fullName>
            <ecNumber evidence="6 15">7.1.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">Nicotinamide nucleotide transhydrogenase subunit beta</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">S2091_1610</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 15">The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 15">
            <text>H(+)(in) + NAD(+) + NADPH = H(+)(out) + NADH + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:47992"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="7.1.1.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell inner membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 15">Belongs to the PNT beta subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.1.1.1" evidence="6 15"/>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93609">
        <property type="protein sequence ID" value="PRC93609"/>
        <property type="gene ID" value="S2091_1610"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008750">
        <property type="term" value="F:NAD(P)+ transhydrogenase (AB-specific) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012136">
        <property type="entry name" value="NADH_DH_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034300">
        <property type="entry name" value="PNTB-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02233">
        <property type="entry name" value="PNTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000204">
        <property type="entry name" value="PNTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="SSF52467"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 15" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="8 15" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="14 15 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-0520">NAD</keyword>
    <keyword evidence="11 15" id="KW-0521">NADP</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12 15" id="KW-1278">Translocase</keyword>
    <keyword evidence="10 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="13 16" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="36"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="59"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="95"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="136"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="180"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="205"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="254"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="domain" description="PNTB" evidence="17">
        <location>
            <begin position="8"/>
            <end position="474"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00007919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00014581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRNR" id="PIRNR000204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF02233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="PRC93609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="477" mass="49839" checksum="96A608161B379B7C" modified="2018-07-18" version="1">MSINLVVMLYLIASVCFIQALKGLSHPTSARRGNAFGMAGMAIAVVTTIAMMMELKSQLAGSGMGLALVVGGVVVGGVIGATLAKRVEMTKMPELVAAMHSLIGLAAVCIAVAVVSEPWAFNLTEKGGLIPFGNRIELFIGTFVGAITFSGSVIAFGKLSGKYKFRLFQGAPVSFTGQHMLNLVLALAMFGCGIAFCVTQSWTPFAVMAAIAFALGVLIIIPIGGADMPVVVSMLNSYSGWAAAGIGFSLNNSMLIIAGSLVGSSGAILSYIMCKAMNRSFFNVLLGGFGGAPAEAATGTQAARNVKSGSADDVAFLLGNAETVIIVPGYGLAVARAQHSLKELTEHLTEKGISVKYAIHPVAGRMPGHMNVLLAEAEVPYDQVFEMEDINNEFAQADVVLVLGANDVVNPAAKDPKSPIAGMPILEAYKAKTVIVNKRSMASGYAGLDNELFYMDKTMMVFGDAKKVIEDMVKALD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0Y7</accession>
    <name>A0A2S9H0Y7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ABC-type Fe3+-siderophore transport system permease component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_1629</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93628">
        <property type="protein sequence ID" value="PRC93628"/>
        <property type="gene ID" value="S2091_1629"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037294">
        <property type="entry name" value="ABC_BtuC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000522">
        <property type="entry name" value="ABC_transptr_permease_BtuC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30472">
        <property type="entry name" value="PTHR30472"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01032">
        <property type="entry name" value="FecCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81345">
        <property type="entry name" value="SSF81345"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="82"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="111"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="140"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="174"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="217"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="266"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="306"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="337"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC93628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="362" mass="37447" checksum="B1FE5884431A7ACC" modified="2018-07-18" version="1">MILAPAQQSLQLRSVNLTIPVLLLILCAIIIISIGSGAVPIAPRQVLAILGSKIGWGGEWIKLADFSDQQAAVLSLIRLPRVLLGILVGAGLACSGVALQGLFRNPLADPGLIGVSGGAALGATSVIVMGATWLPGLSQSLGLFTLPLAAFLGGFGIAFLIYQLARNGGITALPIMLLAGIAVNSLTGAAIGSFTYIADDAQLRSLTFWSMGSLGNASWDIIALLTPIVTIAIYGMARLIPALNALALGEAEAGHMGFNTNQIKRWAIFWSALAVGSLVAFTGMIGFIGLVTPHVIRLLCGPNHRIVMPASALLGAIFILLADLCARTAVAPAEIPIGILTALIGAPFFLGLLLKQRANWRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H128</accession>
    <name>A0A2S9H128_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Protoheme IX farnesyltransferase</fullName>
            <ecNumber evidence="10">2.5.1.141</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Heme B farnesyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Heme O synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">ctaB</name>
        <name evidence="11" type="ORF">S2091_1693</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>(2E,6E)-farnesyl diphosphate + H2O + heme b = diphosphate + Fe(II)-heme o</text>
            <dbReference type="Rhea" id="RHEA:28070"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
            <dbReference type="ChEBI" id="CHEBI:60530"/>
            <dbReference type="ChEBI" id="CHEBI:175763"/>
            <dbReference type="EC" id="2.5.1.141"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="10">Porphyrin-containing compound metabolism; heme O biosynthesis; heme O from protoheme: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cell membrane</location>
            <topology evidence="10">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="10">Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.141" evidence="10"/>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93692">
        <property type="protein sequence ID" value="PRC93692"/>
        <property type="gene ID" value="S2091_1693"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00834">
        <property type="reaction ID" value="UER00712"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008495">
        <property type="term" value="F:protoheme IX farnesyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048034">
        <property type="term" value="P:heme O biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd13957">
        <property type="entry name" value="PT_UbiA_Cox10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00154">
        <property type="entry name" value="CyoE_CtaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006369">
        <property type="entry name" value="Protohaem_IX_farnesylTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000537">
        <property type="entry name" value="UbiA_prenyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030470">
        <property type="entry name" value="UbiA_prenylTrfase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044878">
        <property type="entry name" value="UbiA_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43448">
        <property type="entry name" value="PTHR43448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01040">
        <property type="entry name" value="UbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01473">
        <property type="entry name" value="cyoE_ctaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00943">
        <property type="entry name" value="UBIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="3 10" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 10" id="KW-0350">Heme biosynthesis</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10 11" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="21"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="44"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="89"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="118"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="143"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="168"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="212"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="239"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="271"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC93692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="294" mass="32705" checksum="898DED51CB1AB2BD" modified="2018-07-18" version="1">MNTMIDQPSRLSQYLALTKPRVTQLAVFCAVIGMFLATPDMPDWHIVLAASIGIWLLAGAAFAVNCLMEREIDALMARTARRASAQGEISVKQICVFSAIIGGAGMLVLYFLVNPLTMWLTLVTFIGYAVIYTVLLKPATPQNIVIGGLSGAMPPALGWAAIANDVPMQAWLLVLIIFVWTPPHFWALALYRRDDYAKSGLPMLPITHGMKFTGLHIWLYTIALVATTTLPFAVRMSGLIYLVSAMLLGAIFLYYAWQIHRNYSDKLARKTFTFSIIYLSLLFAALLVDHYFKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H173</accession>
    <name>A0A2S9H173_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Sterol desaturase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1732</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93731">
        <property type="protein sequence ID" value="PRC93731"/>
        <property type="gene ID" value="S2091_1732"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008610">
        <property type="term" value="P:lipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006694">
        <property type="entry name" value="Fatty_acid_hydroxylase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04116">
        <property type="entry name" value="FA_hydroxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="41"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="162"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="domain" description="Fatty acid hydroxylase" evidence="2">
        <location>
            <begin position="88"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="272" mass="30982" checksum="EA8342C9991D2393" modified="2018-07-18" version="1">MSVVRLCAWLVLLSLIFLPLEKLFALQPQKFFCKSLLSDLGYFFINGLLPGLLLAIPLSFLAFGVHSLVPHTMQTTVAAWPLWLRISIGFVVGEIGFYWGHRWCHEVPFLWRFHSLHHSAEHIYFLISSRAHPVDNVFIRLCGLIPAYVLGVASPLTPNGSLVPILIVLVATTWGFFIHSNLNWRLGPLEWLISTPAFHHWHHTLGEQRDCNYASMLPWVDQLFGTYHLPRNQWPSAYGIEQQLPASLGEQLLYPFHPHPPVSLPKSVTAEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H183</accession>
    <name>A0A2S9H183_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">MAPEG family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_1742</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93741">
        <property type="protein sequence ID" value="PRC93741"/>
        <property type="gene ID" value="S2091_1742"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.550">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023352">
        <property type="entry name" value="MAPEG-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001129">
        <property type="entry name" value="Membr-assoc_MAPEG"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01124">
        <property type="entry name" value="MAPEG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161084">
        <property type="entry name" value="SSF161084"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="74"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="102"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC93741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="125" mass="13609" checksum="FF7148BBD80F308F" modified="2018-07-18" version="1">MKLTAWATLASVLMYIWVFAKVGKARGVHKVPAPLTDGPVEFLIALRVQANTVEQLIIFLPLLWLCCIFMSDQIAAILGAIWVVGRILYALGYYQAPDKRSLGFLISSVAAIGLLISAVTGLIIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1J0</accession>
    <name>A0A2S9H1J0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_1436</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93827">
        <property type="protein sequence ID" value="PRC93827"/>
        <property type="gene ID" value="S2091_1436"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015562">
        <property type="term" value="F:efflux transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003423">
        <property type="entry name" value="OMP_efflux"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010131">
        <property type="entry name" value="RND_efflux_OM_lipoprot_NodT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02321">
        <property type="entry name" value="OEP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01845">
        <property type="entry name" value="outer_NodT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2 4" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0564">Palmitate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1134">Transmembrane beta strand</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015368336" evidence="2">
        <location>
            <begin position="21"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="75"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="186"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU362097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC93827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="484" mass="51926" checksum="14CA3A61AF1EA91D" modified="2018-07-18" version="1">MISKKFIAEKFVLANAVALALISLSGCNVGPDYVRPTTLAEAGIPKEFKENWKAAQPQDHEIPAKWWTIFNDDNLNTLIEQVATSNLTLAQAEANYRAASALVDNAKAAYFPSLTGNLSRTRSNSLMAGTTTVNSVGVAASWEVDLWGSVRRAVEVQENTALSSFANVQATRLSMQSQLAQNYFQLRVLDAQKELLERTVEEYRRSLTLTQNQYKSGVVATDSVLLAETQLQSTEAQALEVGIQRAQLEHAIAILIGKTPASFSIAAIPIGTTAYMPEMPEIPVGVPSSLLERRPDVAASERSVAAANAQIGVTKAAYFPNLTLGGSGGYQSSTLANWISLPNRVWSVGPALAATLFDGGAKRAQNAQAVAAYDASVAGYRQTVLVAFQNVEDNLASLRILKDEYIVQNAATISARKALAVTMNQYKAGTVNYLNVVTAQTTALTNERSELTITNSRLIAAVQLIAALGGGWNGLDNKDKVAQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1L0</accession>
    <name>A0A2S9H1L0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PrgH: type III secretion apparatus protein PrgH/EprH</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1484</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93875">
        <property type="protein sequence ID" value="PRC93875"/>
        <property type="gene ID" value="S2091_1484"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013387">
        <property type="entry name" value="T3SS_PrgH/EprH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019029">
        <property type="entry name" value="T3SS_PrgH/EprH-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09480">
        <property type="entry name" value="PrgH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02554">
        <property type="entry name" value="PrgH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="148"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="399" mass="44505" checksum="1CF253DAFA27E1E3" modified="2018-07-18" version="1">MSLHFEVESPQVKAVLRLLSGPLCGCEYQLNDGVTLVVAGAVGTLLGVVDGKELSGMPEFPERAIVVPLEGGRNFEIIIDDNARSGFRLRTLEPQLEEWGCVYQEICQMGSLRFAVRPMDVDWEPGIVEPLLPLTEVVSLPQRRSWGVSVLIGAAALVVVLGLVLVLWTVLNEDKRVAEVASVVAGSSDAYRLVSGRDGAVYVFAKNERDVSWAKQALSREGLISAARVVTLPDEEARLGKLLVESYPVLAFYRMRLLDPAKPVLVLSQERAQISSQMSRELMANMMSWMPYAKSIDVVNWSDAMLDERAQAGLDRLGINYDRISNASSVTYVVQSSLTDIQLVHLQDFIGNYYREFGMRYIYFSVALKDDWLKGKSFKYGGSGYVKMTQQHWFFPQSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1P4</accession>
    <name>A0A2S9H1P4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1395</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93786">
        <property type="protein sequence ID" value="PRC93786"/>
        <property type="gene ID" value="S2091_1395"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007497">
        <property type="entry name" value="DUF541"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04402">
        <property type="entry name" value="SIMPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015479834" evidence="1">
        <location>
            <begin position="21"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="238" mass="25547" checksum="622B17D52E9290FB" modified="2018-07-18" version="1">MLKHFFIFCMLLGSATIVCASQLPDYPFIHSVGNAGIYAQPDIGEISFEITVSDAESDKATQQAVAINADILALLAAQNIPAADVEIYEVQKKMRAVEGVDGKPATVICDIKQSIIINVRDLSKWEGLTTPLLGTNNLGNFDTSFERTDRHKINDELIAAAVKDAQHNGMLMVESFGKHLGAAMAISSGKLKDVSIALGLATGGLSSDDAPKGNPIRNFFAPAPLRFTQSVDVLFKIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1Q0</accession>
    <name>A0A2S9H1Q0_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Flagellar basal body protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_1511</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 4">Bacterial flagellum basal body</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the flagella basal body rod proteins family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93902">
        <property type="protein sequence ID" value="PRC93902"/>
        <property type="gene ID" value="S2091_1511"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009425">
        <property type="term" value="C:bacterial-type flagellum basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001444">
        <property type="entry name" value="Flag_bb_rod_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020013">
        <property type="entry name" value="Flagellar_FlgE/F/G"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010930">
        <property type="entry name" value="Flg_bb/hook_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037925">
        <property type="entry name" value="FlgE/F/G-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00460">
        <property type="entry name" value="Flg_bb_rod"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06429">
        <property type="entry name" value="Flg_bbr_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117143">
        <property type="entry name" value="SSF117143"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03506">
        <property type="entry name" value="FlgEFG_subfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0975">Bacterial flagellum</keyword>
    <keyword evidence="7" id="KW-0966">Cell projection</keyword>
    <keyword evidence="7" id="KW-0969">Cilium</keyword>
    <keyword evidence="7" id="KW-0282">Flagellum</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flg_bb_rod" evidence="5">
        <location>
            <begin position="7"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="domain" description="Flg_bbr_C" evidence="6">
        <location>
            <begin position="170"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU362116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF06429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC93902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="245" mass="26043" checksum="A8C8EA4AE8B9D033" modified="2018-07-18" version="1">MADAFSIAIQSMQNDMQRMDIISENVANSATPGYRRALSTNQSFGDVLQSSSLSNVTHSIEITLPTVTSVLDTASGSIKSTSQPLDLAISGDGYFELTTPDGLAYTRAGNFHINEDGHLVSQDGYPVSGKGGDIIVNGKSTPTITPSGEVSDGSTAVGQIRIVSFADKHGLQTRSGGLLVSTNNDAETSDSSAQLQIGFLENANVIPLNEMVSMLETSRHFESQQKLFQGYDEQISSAIQKLGQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1T1</accession>
    <name>A0A2S9H1T1_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Indole-3-glycerol phosphate synthase</fullName>
            <shortName evidence="8">IGPS</shortName>
            <ecNumber evidence="8">4.1.1.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">trpC</name>
        <name evidence="10" type="ORF">S2091_1117</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate + H(+) = (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate + CO2 + H2O</text>
            <dbReference type="Rhea" id="RHEA:23476"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:58613"/>
            <dbReference type="ChEBI" id="CHEBI:58866"/>
            <dbReference type="EC" id="4.1.1.48"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 4/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the TrpC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.48" evidence="8"/>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC93944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93944">
        <property type="protein sequence ID" value="PRC93944"/>
        <property type="gene ID" value="S2091_1117"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00035">
        <property type="reaction ID" value="UER00043"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004425">
        <property type="term" value="F:indole-3-glycerol-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000162">
        <property type="term" value="P:tryptophan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00331">
        <property type="entry name" value="IGPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00134_B">
        <property type="entry name" value="IGPS_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045186">
        <property type="entry name" value="Indole-3-glycerol_P_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013798">
        <property type="entry name" value="Indole-3-glycerol_P_synth_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001468">
        <property type="entry name" value="Indole-3-GlycerolPSynthase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22854">
        <property type="entry name" value="PTHR22854"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00218">
        <property type="entry name" value="IGPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="SSF51366"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00614">
        <property type="entry name" value="IGPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6 8" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="4 8" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="7 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0822">Tryptophan biosynthesis</keyword>
    <feature type="domain" description="IGPS" evidence="9">
        <location>
            <begin position="5"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001633"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC93944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="266" mass="29074" checksum="3420F7041875E4FA" modified="2018-07-18" version="1">MSDILTKILDVKADEVRAAKKYQALTSLRREVEENTDLRAGVRDFEASMRNKIQAGAAGVIAEIKKASPSKGIIRADFDPAQIAASYATHGAACLSVLTDVQFFQGAPEYLQQARAACTLPALRKDFMIDPYQIYQARSWGADAILLIVAALDAGLMRELESIAHELGMAVLVEVHNADELKAALTLKTALLGINNRNLRTFDVSLENTIVLLPQIPAEKLVITESGITSVEDVKRMRDVNVNGFLVGEAFMRAPEPGMEMARLFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1U8</accession>
    <name>A0A2S9H1U8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ubi-OHases: ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_1122</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; ubiquinone biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the UbiH/COQ6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC93949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93949">
        <property type="protein sequence ID" value="PRC93949"/>
        <property type="gene ID" value="S2091_1122"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00232"/>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006744">
        <property type="term" value="P:ubiquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010971">
        <property type="entry name" value="UbiH/COQ6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01988">
        <property type="entry name" value="Ubi-OHases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0830">Ubiquinone</keyword>
    <feature type="domain" description="FAD_binding_3" evidence="4">
        <location>
            <begin position="4"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC93949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="390" mass="42291" checksum="9A1AFC44CBAD9614" modified="2018-07-18" version="1">MRCEIGVIGNGAVGKAVALGFAQAGFQVILLGPSDRAATVRAISPEWDARVFALNHTAKNLLSKLKVWDALDLQRVAPIESMQVFDDAGAALNLDAYAAYQNELAWIVEDQNLNQALDAALRFAPNVQLMTGKTVAMSADFSELTLENGATLQAELWVGADGAQSWLRNQADIGLDYRSYDQRGVVANFSCAKPHHGIAHQWFIGEQGIVALLPLPGQQVSLVWSAPEALAVTLLGETTHQLAQRLARYCGEVLGELVPLPPQRVQAFPLNFISPHSIIGPRLALVGDAAHVVHPLAGHGMNLGFADVVALLQTVAEREAWRSCGDTRVLQRYARARKEDVLLMQLATDGLSRLFGSQLSPLQTVRNMGMTIVNKLPFLKKQLILQAMGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H215</accession>
    <name>A0A2S9H215_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1195</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94022">
        <property type="protein sequence ID" value="PRC94022"/>
        <property type="gene ID" value="S2091_1195"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="193"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="238" mass="24382" checksum="7AB6957643355DC5" modified="2018-07-18" version="1">MTQSASSDAFNDSLSFVKKLWGGMSVPGMTVPGMSMPVPSMSLEDMDKRIQELKTVESWLTVNMTMLHSTIQALEIQRATIATLHSLSSTMAQTMQSVNSSGTSNPFAAGLASESGAAAATKSGAQEDADVAPLMSQSATWWNGVQEQFKQALGTALANSAANYEVAKSVTEDATKAATDAATQLVAKATNLKASASAAPKPPAKGATKSAPKSPAKPVPKAASKAKTGAASKTGKSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H217</accession>
    <name>A0A2S9H217_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Glutamate synthase, NADH/NADPH, small subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_1192</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="4">Amino-acid biosynthesis.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94019">
        <property type="protein sequence ID" value="PRC94019"/>
        <property type="gene ID" value="S2091_1192"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00148"/>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016639">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006537">
        <property type="term" value="P:glutamate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1060.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028261">
        <property type="entry name" value="DPD_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006005">
        <property type="entry name" value="Glut_synth_ssu1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009051">
        <property type="entry name" value="Helical_ferredxn"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14691">
        <property type="entry name" value="Fer4_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01317">
        <property type="entry name" value="GOGAT_sm_gam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="3" id="KW-0314">Glutamate biosynthesis</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="5">
        <location>
            <begin position="37"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00029440"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC94019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="487" mass="53275" checksum="50EB7F8827577035" modified="2018-07-18" version="1">MGKVTGFMEYARLQEAAEAPATRVKHHKEFLLHLDDAAAKTQAARCMDCGIPFCNNGCPVNNIIPDWNDLVYRGNYQEALDTLHSTNNFPEFTGRICPAPCETACTLGINSDAVGIKSIEHFIIDKGWENAWIKPQIASSSTGKKIAIVGSGPAGMAAAQQLARVGHAVTVFEKNDRVGGLLRYGIPDFKLEKLHIDRRVEQMQAEGVVFKTGVLVGDDFPQNITNWSQETISAAQLQEQFDAIIMAGGAEQPRDLPVPGRELKGVHFAMDFLPQQNKVNAGDKVKEQIKATGKHVVVIGGGDTGSDCVGTSNRHGAASVSQFEVMPMPPEQENIPLVWPYWPLKLRTSSSHEEGCQRDWSVATKRLEGRNGKVEKLIAARVEWRDGKMQEVADSEFEIKADLVLLAMGFVSPVQQTLTSFGVEQDARGNVRATTEGVKAYVSSVNKVFTAGDMRRGQSLVVWAIREGRQCAQAVDKFLMGSSLLPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H218</accession>
    <name>A0A2S9H218_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Phosphoribosyl-ATP pyrophosphatase</fullName>
            <shortName evidence="8">PRA-PH</shortName>
            <ecNumber evidence="8">3.6.1.31</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">hisE</name>
        <name evidence="9" type="ORF">S2091_1173</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>1-(5-phospho-beta-D-ribosyl)-ATP + H2O = 1-(5-phospho-beta-D-ribosyl)-5'-AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:22828"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:59457"/>
            <dbReference type="ChEBI" id="CHEBI:73183"/>
            <dbReference type="EC" id="3.6.1.31"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 2/9.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the PRA-PH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.31" evidence="8"/>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94000">
        <property type="protein sequence ID" value="PRC94000"/>
        <property type="gene ID" value="S2091_1173"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00007"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004636">
        <property type="term" value="F:phosphoribosyl-ATP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd11534">
        <property type="entry name" value="NTP-PPase_HisIE_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01020">
        <property type="entry name" value="HisE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008179">
        <property type="entry name" value="HisE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021130">
        <property type="entry name" value="PRib-ATP_PPHydrolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01503">
        <property type="entry name" value="PRA-PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03188">
        <property type="entry name" value="histidine_hisI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 8" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="5 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC94000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="126" mass="13972" checksum="1E509862DB8F6896" modified="2018-07-18" version="1">MSNTLQRLADVIESRKLANGGDPEKSYVSRLFAKGDDAILKKIGEEATETVMAAKDARVSGERSGLVYECADLWFHSLIMLAQFDISPQAVLDELARREGISGIEEKAARKDVLRDELEHSKHQQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H278</accession>
    <name>A0A2S9H278_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltransferase domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1241</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94068">
        <property type="protein sequence ID" value="PRC94068"/>
        <property type="gene ID" value="S2091_1241"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013217">
        <property type="entry name" value="Methyltransf_12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016584">
        <property type="entry name" value="MeTrfase_VrtF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08242">
        <property type="entry name" value="Methyltransf_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF011491">
        <property type="entry name" value="Mtase_YbcY_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_12" evidence="1">
        <location>
            <begin position="61"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="225" mass="25321" checksum="8E3F748121214F46" modified="2018-07-18" version="1">MNNIAQELSIAKVKRSQRYFNKASLSIYDFILYGFISKYAWGSSIQRLDAHYKKYVSLSHLEVGVGTGYLLNRIKFATPSPRLALMDLSQACLEKTKIKVSRYAPEIYVQNLLEPMQRSIPQFDSVSINYVLHCIPGSISQKCQALLHLKPLLKQDGILFGTTVLSTGVPKNLLARPAMSFLNLLGVFNNSEDSAIDLEKFLKAHFKITHFEVIGVTAFFAVKIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2A2</accession>
    <name>A0A2S9H2A2_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="19">Thiol:disulfide interchange protein DsbD</fullName>
            <ecNumber evidence="19">1.8.1.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="19">Protein-disulfide reductase</fullName>
            <shortName evidence="19">Disulfide reductase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19" type="primary">dsbD</name>
        <name evidence="21" type="ORF">S2091_1288</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21 22">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="19">Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 19">
            <text>[protein]-dithiol + NAD(+) = [protein]-disulfide + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:18749"/>
            <dbReference type="Rhea" id="RHEA-COMP:10593"/>
            <dbReference type="Rhea" id="RHEA-COMP:10594"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.8.1.8"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 19">
            <text>[protein]-dithiol + NADP(+) = [protein]-disulfide + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:18753"/>
            <dbReference type="Rhea" id="RHEA-COMP:10593"/>
            <dbReference type="Rhea" id="RHEA-COMP:10594"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.8.1.8"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4 19">Cell inner membrane</location>
            <topology evidence="4 19">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 19">Belongs to the thioredoxin family. DsbD subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.8.1.8" evidence="19"/>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94115">
        <property type="protein sequence ID" value="PRC94115"/>
        <property type="gene ID" value="S2091_1288"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047134">
        <property type="term" value="F:protein-disulfide reductase (NAD(P)) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017004">
        <property type="term" value="P:cytochrome complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02953">
        <property type="entry name" value="DsbDgamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1250">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00399">
        <property type="entry name" value="DbsD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003834">
        <property type="entry name" value="Cyt_c_assmbl_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035671">
        <property type="entry name" value="DsbD_gamma"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028250">
        <property type="entry name" value="DsbDN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036929">
        <property type="entry name" value="DsbDN_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022910">
        <property type="entry name" value="Thiol_diS_interchange_DbsD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32234:SF0">
        <property type="entry name" value="PTHR32234:SF0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11412">
        <property type="entry name" value="DsbC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02683">
        <property type="entry name" value="DsbD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74863">
        <property type="entry name" value="SSF74863"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 19" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="7 19" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="11 19" id="KW-0201">Cytochrome c-type biogenesis</keyword>
    <keyword evidence="17 19" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="12 19" id="KW-0249">Electron transport</keyword>
    <keyword evidence="16 19" id="KW-0472">Membrane</keyword>
    <keyword evidence="15 19" id="KW-0520">NAD</keyword>
    <keyword evidence="14 19" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="18 19" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <keyword evidence="9 19" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="13 19" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6 19" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="183"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="227"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="263"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="307"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="342"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="380"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="20">
        <location>
            <begin position="449"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="19">
        <location>
            <begin position="135"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="19">
        <location>
            <begin position="202"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="19">
        <location>
            <begin position="503"/>
            <end position="506"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00007241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="PRC94115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="591" mass="63797" checksum="99BB1E0C31F0251A" modified="2018-07-18" version="1">MSPLPRTTSSKIFAVLNQLIVSLLFLCGLTNAIADTDFLEPEQAFQFSSKQIAPDRIEVTYLIADGYYMYRERYKFVAIGATLGEPIFPKGHVKFDETFQKNVETFTHSITVQIPILSVDTAQPKFTLISHGQGCSEQGLCYAPLESKQTFDTAKFKFESTAPPTAGGDDSNKLRNSLQSGRLIIIMPLFLLLGLGLAFTPCVLPMVPILSSIIVGEGASVGRQRGLILSLSYSFGMAIVYTALGVAAGLLGEGLAAALQNPWVLGAFGLLLVGLSLSMFNVYHLQVPAFLQSKLSQVSDQQRAGKLIGVFVMGAISALIIGPCVAAPLASALLYISQTRNVLIGGAALFSMAMGMSVPLILVGLSAGSLLPRAGRWMEAVKQLFGVLMLAMALWLVSPVLPVWLQMLGWATLLIGYGVFLLRHRAVLGKAVALALCVLGGMELIGAASGGRDVFAPLSHFYNQSGAHIQFARVKSLAELEHALQAAKVQGKPVMLDFYADWCVSCKEMEKFTFTDQRIQAKFATMVLLQVDVTANNEDVKALLKRFNLFGPPGMIFFDLDSNESGRVIGFEKAEKFVTSLANFVVVKATP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2M8</accession>
    <name>A0A2S9H2M8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">FecR protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0852</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94231">
        <property type="protein sequence ID" value="PRC94231"/>
        <property type="gene ID" value="S2091_0852"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00118">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006860">
        <property type="entry name" value="FecR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036779">
        <property type="entry name" value="LysM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016930">
        <property type="entry name" value="UCP029644"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04773">
        <property type="entry name" value="FecR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01476">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029644">
        <property type="entry name" value="UCP029644"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51782">
        <property type="entry name" value="LYSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015753335" evidence="1">
        <location>
            <begin position="24"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="2">
        <location>
            <begin position="36"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="553" mass="60251" checksum="A6273031007C9A9F" modified="2018-07-18" version="1">MTIVTFKRFIFLFVLSISLSSYAQQPGDVVVGKSDITYYAKQGDTLISIAQTYTEKSSNWALLGKRNRIGNDRAIPIGTGIQIPFELLRELTIEAKVVAFSGEATLNNGSATSPITIGAIVREGMVVSTEKNGFATIELPDHSRISVPSNSQVKFSKLRATEYANSPKTELTLLTGRVESSVTSLKNNNGRFEVHSPLAIAGVRGTHFRVEATEHQVATEVLEGNVAVGQTVRPNAITLPAGKGDIVNAQKVGEAVALLPAPTLIGNYALQERILVQFKVVKMDEAKSYRAQIALDNKAENLIQEGVFTEPHFKFSDIADGNYFVRISAIDALGLEGFSNIIPFKLKARPEAPFNIQPKKKLRAEQVDFSWSEAADAAFYHLQIASDAEFQHLLQDHPKLSATHYSADQLPIGHFFWRVASISQKNGVDDHGPFGDVENVELLAPTKDLPPFKDSGGATMNLSWSAEPGQTFVLQMSDDAAFTHLILDQQLPAPEFNLPRPKPGIYFIRVKAIDADGYVGAFSGTQTITIFNLLTSSDGSPVHSLDGVVHIGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2P6</accession>
    <name>A0A2S9H2P6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0834</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94213">
        <property type="protein sequence ID" value="PRC94213"/>
        <property type="gene ID" value="S2091_0834"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="149" mass="16936" checksum="2166DD02D89223A2" modified="2018-07-18" version="1">MPCEGTAQFADCFIEEDNALLNSGDIHQKKSTLNVHEYSGGIQALVFNKHILKHLPSQSILGTVYSAHEIEITNFFKLMPNYIEEFGIGCSIENVTGTLSVGDKLLTDYEHEVCFLIMMNWDFKQITMRIHCHFTPLLLLQCSLFFTIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2S5</accession>
    <name>A0A2S9H2S5_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Phospho-2-dehydro-3-deoxyheptonate aldolase</fullName>
            <ecNumber evidence="3">2.5.1.54</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_0902</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>D-erythrose 4-phosphate + H2O + phosphoenolpyruvate = 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:14717"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16897"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58394"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="EC" id="2.5.1.54"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the class-II DAHP synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.54" evidence="3"/>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94281">
        <property type="protein sequence ID" value="PRC94281"/>
        <property type="gene ID" value="S2091_0902"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003849">
        <property type="term" value="F:3-deoxy-7-phosphoheptulonate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002480">
        <property type="entry name" value="DAHP_synth_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21337">
        <property type="entry name" value="PTHR21337"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01474">
        <property type="entry name" value="DAHP_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU363071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC94281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="431" mass="47405" checksum="48A48655E30134FE" modified="2018-07-18" version="1">MFSNRTPWSPSSWQSMSQRQLPHYQDDAALQQVLARIQSYPRLVAISEIRRLTSRMARVAHGRGFILQGGDCAESFSDFCPKIIRQHYHLLQQMAAMIGAASHQPVVRIGRIAGQYAKPRSSAMECVAGQELPSYRGDMINGAEFQEQARQTDPLRMETAYFKAAGSLNYLRSLNSEANASRAGSYFTSHEALLLPYEQSMLEQDAMGNWYCGSGHFLWIGERTRALDGAHVEFLRGVCNPIGVKLGPTVSREELIRLIDVLNPFNEAGRLTLIVRNGAAHIDRLPKLLEAIQLEGREVLWMCDPMHGNGIQTADGIKTRDFASIQAELNGFLDAHRKIGTHPGGVHLELTGLNVSECLGGPSKVSEADLATGYLSACDPRLNPEQAMALTATLVNQLGLASERATSPIAPKAQVGLPAVHAQHLDWESRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2Z7</accession>
    <name>A0A2S9H2Z7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0975</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94354">
        <property type="protein sequence ID" value="PRC94354"/>
        <property type="gene ID" value="S2091_0975"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="309" mass="34293" checksum="4EDE23D75E14404E" modified="2018-07-18" version="1">MSTAARIPDHILVFNGWDGYLAQHLYPTAVVSTLKFVDGCISFDPIEIEKCTLLLIHFDISYLGGLLNEFQGLFDAIRSNGGVIWNSGILDIRKSAVQKHAQKIGLPTLRASPEINQDTFLLLKTELNARGCPEERLPCDVLCKLGLPTLSKTACISEYPYLRAGDLSAEIWEDKNLHIERFIHRSDGIFFRVFFSGQHCILCEGQSNAVIKRMESASGRNDSLLTRDQSSDALVCLLLGSLKANVFAAAVTFSNAIELDFGAVDLVVDDDDVVYVVDVNLTPYWGQQKMLPTYLKHFTGSLYQPASLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H360</accession>
    <name>A0A2S9H360_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0994</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94373">
        <property type="protein sequence ID" value="PRC94373"/>
        <property type="gene ID" value="S2091_0994"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="112" mass="13085" checksum="12CFAD501ADCDE8F" modified="2018-07-18" version="1">MLKIYKTTSEVIPEGRLILELSEDKTGGGENNLYWITSRDKNLIRDLRHVMRENQTQFWHRFGVTQTQGSRFERGKPIPLPVLLLIRLYLLRVIDDSNLQQVRSPSFDSEGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H388</accession>
    <name>A0A2S9H388_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Helix-turn-helix domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0947</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94326">
        <property type="protein sequence ID" value="PRC94326"/>
        <property type="gene ID" value="S2091_0947"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="24"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="113" mass="12502" checksum="6B8BBCDA15BCA9CE" modified="2018-07-18" version="1">MRVTLSLALPTELAVESEKIGARLARLRVARHISQTEAALRAGISRNTAYRLEKGDPGVAIGQLLRYLDVIAPGKSLQSFFAESDPSIAALGERERKKRVRSLSKKELEELNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3A7</accession>
    <name>A0A2S9H3A7_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">ATP-dependent protease subunit HslV</fullName>
            <ecNumber evidence="7">3.4.25.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">hslV</name>
        <name evidence="8" type="ORF">S2091_1071</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>ATP-dependent cleavage of peptide bonds with broad specificity.</text>
            <dbReference type="EC" id="3.4.25.2"/>
        </reaction>
    </comment>
    <comment type="activity regulation">
        <text evidence="7">Allosterically activated by HslU binding.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the peptidase T1B family. HslV subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.25.2" evidence="7"/>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94450">
        <property type="protein sequence ID" value="PRC94450"/>
        <property type="gene ID" value="S2091_1071"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009376">
        <property type="term" value="C:HslUV protease complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005839">
        <property type="term" value="C:proteasome core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004298">
        <property type="term" value="F:threonine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051603">
        <property type="term" value="P:proteolysis involved in protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01913">
        <property type="entry name" value="protease_HslV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00248">
        <property type="entry name" value="HslV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022281">
        <property type="entry name" value="ATP-dep_Prtase_HsIV_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023333">
        <property type="entry name" value="Proteasome_suB-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194">
        <property type="entry name" value="PTHR32194"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039093">
        <property type="entry name" value="HslV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03692">
        <property type="entry name" value="ATP_dep_HslV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51476">
        <property type="entry name" value="PROTEASOME_BETA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0021">Allosteric enzyme</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 7 8" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7" id="KW-0915">Sodium</keyword>
    <keyword evidence="4 7" id="KW-0888">Threonine protease</keyword>
    <feature type="active site" evidence="7">
        <location>
            <position position="7"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="162"/>
        </location>
        <ligand>
            <name>Na(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="165"/>
        </location>
        <ligand>
            <name>Na(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="168"/>
        </location>
        <ligand>
            <name>Na(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC94450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="178" mass="19220" checksum="5BC04A7391B64BD0" modified="2018-07-18" version="1">MEQFHGTTILSVRRGNSVALGGDGQVTLGNIVMKGTARKVRKLYHGKVLAGFAGGTADAFTLIERFEAKLEKHQGHLMRASVELAKDWRTDRMLRRLEAMLLVADRETTLVITGNGDVLEPEDGIGAIGSGGTFAQSAAKALQENTELSPIEIVKKSLTIAGELCIYTNLSHTIETLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3M4</accession>
    <name>A0A2S9H3M4_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Acetylglutamate kinase</fullName>
            <ecNumber evidence="8">2.7.2.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">N-acetyl-L-glutamate 5-phosphotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">NAG kinase</fullName>
            <shortName evidence="8">NAGK</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">argB</name>
        <name evidence="10" type="ORF">S2091_1087</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>ATP + N-acetyl-L-glutamate = ADP + N-acetyl-L-glutamyl 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:14629"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:44337"/>
            <dbReference type="ChEBI" id="CHEBI:57936"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.2.8"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="8">Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 2/4.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the acetylglutamate kinase family. ArgB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.2.8" evidence="8"/>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94466">
        <property type="protein sequence ID" value="PRC94466"/>
        <property type="gene ID" value="S2091_1087"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00068">
        <property type="reaction ID" value="UER00107"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003991">
        <property type="term" value="F:acetylglutamate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042450">
        <property type="term" value="P:arginine biosynthetic process via ornithine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04250">
        <property type="entry name" value="AAK_NAGK-C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00082">
        <property type="entry name" value="ArgB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036393">
        <property type="entry name" value="AceGlu_kinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004662">
        <property type="entry name" value="AcgluKinase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037528">
        <property type="entry name" value="ArgB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001048">
        <property type="entry name" value="Asp/Glu/Uridylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041727">
        <property type="entry name" value="NAGK-C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00696">
        <property type="entry name" value="AA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000728">
        <property type="entry name" value="NAGK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53633">
        <property type="entry name" value="SSF53633"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00761">
        <property type="entry name" value="argB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2 8" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AA_kinase" evidence="9">
        <location>
            <begin position="57"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="8">
        <location>
            <begin position="97"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="119"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="221"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="8">
        <location>
            <position position="62"/>
        </location>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="8">
        <location>
            <position position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC94466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="324" mass="34710" checksum="49FC5E579417C8EA" modified="2018-07-18" version="1">MTNLPPELPSDSLTDAASDLATATPIVSELATDSIPAHIKAEILAEALPYIRKFHGKTIVVKYGGNAMTEERLKHGFARDVILLKLVGMNPVVVHGGGPQIDSALRKIGKQGTFVQGMRITDEETMEVVEWVLGGEVQQDIVMLINHYGGQAVGLTGKDGGLIRARRFEMPDRENPGKFLDIGFVGEIDAINPAVVKALQDDAFIPIISPIGFGVDGQAYNINADVVAGKIAEILKAEKLIMMTNIPGVLDKEGNLVTDLSAREIDEMFADGTISGGMLPKISSALDAAKSGVNTVHIIDGRIEHSLLLEVLTEQAFGTMIRSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3M8</accession>
    <name>A0A2S9H3M8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="9">AzlC protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_0581</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the AzlC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94578">
        <property type="protein sequence ID" value="PRC94578"/>
        <property type="gene ID" value="S2091_0581"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011606">
        <property type="entry name" value="Brnchd-chn_aa_trnsp_permease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34979">
        <property type="entry name" value="PTHR34979"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03591">
        <property type="entry name" value="AzlC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="24"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="81"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010735"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC94578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="102" mass="10915" checksum="0D25F2EE68A939C9" modified="2018-07-18" version="1">MEKLKLNTVHKSLSKADWFEEFKFGSIACLPTVLGYLSIGFSAGALARVSGMSSTEVGLMSLILYAGSGQFIVAGMVQANAAAITIWIAIFFVNLRHLLMAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3R0</accession>
    <name>A0A2S9H3R0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC-type sugar transport systems permease component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_0509</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94506">
        <property type="protein sequence ID" value="PRC94506"/>
        <property type="gene ID" value="S2091_0509"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008643">
        <property type="term" value="P:carbohydrate transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="64"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="96"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="144"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="199"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="255"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="60"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC94506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="281" mass="31819" checksum="110F180795BB133E" modified="2018-07-18" version="1">MQAYLFLTPALVLLVLFSFWPVGFGSFLAFTDFSLVKETHWVGLDNFRYIFDNEMFLTGMKNSVLFLLIVPFIQIGAITLAVLVNNQLHGIRFFRAAYYVPVVTTVSVVGIMWGFMFHEHGTLNYILLKIHAVNAPVGWLSDDAIAIFAIMFVTLWRGLGWYMVMYLAGLQSIPAEMQEAAILDGANRWQRFWKITVPMLYPTIMVCTIMSVLAALKAYQEVDVLTQGGPMNSTFTALYYAYDQGLKHLKLPRGLAASLVVSLFCIAIAMLCLRYLKPKHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3T4</accession>
    <name>A0A2S9H3T4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0642</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94639">
        <property type="protein sequence ID" value="PRC94639"/>
        <property type="gene ID" value="S2091_0642"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015456104" evidence="1">
        <location>
            <begin position="22"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="258" mass="29026" checksum="D7964C1F69E9B16C" modified="2018-07-18" version="1">MKRAIFLMIFFVQLFACEVHAQSAASDVPSEENANTTQTIEVRGIKDPEWKPYRIMLKGLDAFDKYHSLAPKADLKFILRPQVPNMSITDVKLHIEANDVSIPIPISEEGTFVIPRNEAAAEQNAEMIINNKKKNTVLWAPYMRTPGIDINSRRMGDMRLECEIVWAVDQDDLPFIIRNIFRLGGGLCKSSHIGVSVLAPRQITSVTMISGARRESLPIGPGGKSFTPPLFDEKWDNDTIFEFQFSEKSAKENESAID</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H461</accession>
    <name>A0A2S9H461_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0763</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94760">
        <property type="protein sequence ID" value="PRC94760"/>
        <property type="gene ID" value="S2091_0763"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021320">
        <property type="entry name" value="DUF2905"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11146">
        <property type="entry name" value="DUF2905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="65" mass="7371" checksum="8C565F54C8C563F4" modified="2018-07-18" version="1">MIRWVFAIFIGLIVFSALLPWLEKLGVGRLPGDLRFKLFGHVFCLPFASTILISMVVLLIARLLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4F4</accession>
    <name>A0A2S9H4F4_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Isoleucine--tRNA ligase</fullName>
            <ecNumber evidence="10">6.1.1.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Isoleucyl-tRNA synthetase</fullName>
            <shortName evidence="10">IleRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">ileS</name>
        <name evidence="15" type="ORF">S2091_0059</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9 10">Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>ATP + L-isoleucine + tRNA(Ile) = AMP + diphosphate + L-isoleucyl-tRNA(Ile)</text>
            <dbReference type="Rhea" id="RHEA:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:9666"/>
            <dbReference type="Rhea" id="RHEA-COMP:9695"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58045"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78528"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="10">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="10">IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.5" evidence="10"/>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94864">
        <property type="protein sequence ID" value="PRC94864"/>
        <property type="gene ID" value="S2091_0059"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA editing activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004822">
        <property type="term" value="F:isoleucine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006428">
        <property type="term" value="P:isoleucyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07960">
        <property type="entry name" value="Anticodon_Ia_Ile_BEm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.740.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02002">
        <property type="entry name" value="Ile_tRNA_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002300">
        <property type="entry name" value="aa-tRNA-synth_Ia"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033708">
        <property type="entry name" value="Anticodon_Ile_BEm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002301">
        <property type="entry name" value="Ile-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023585">
        <property type="entry name" value="Ile-tRNA-ligase_type1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013155">
        <property type="entry name" value="M/V/L/I-tRNA-synth_anticd-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009008">
        <property type="entry name" value="Val/Leu/Ile-tRNA-synth_edit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010663">
        <property type="entry name" value="Znf_FPG/IleRS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08264">
        <property type="entry name" value="Anticodon_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00133">
        <property type="entry name" value="tRNA-synt_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06827">
        <property type="entry name" value="zf-FPG_IleRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00984">
        <property type="entry name" value="TRNASYNTHILE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="SSF47323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50677">
        <property type="entry name" value="SSF50677"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00392">
        <property type="entry name" value="ileS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10 11" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="6 10 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 10 11" id="KW-0436">Ligase</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 10 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 10 11" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="tRNA-synt_1" evidence="12">
        <location>
            <begin position="32"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="domain" description="Anticodon_1" evidence="14">
        <location>
            <begin position="723"/>
            <end position="881"/>
        </location>
    </feature>
    <feature type="domain" description="zf-FPG_IleRS" evidence="13">
        <location>
            <begin position="930"/>
            <end position="957"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'HIGH' region" evidence="10">
        <location>
            <begin position="63"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'KMSKS' region" evidence="10">
        <location>
            <begin position="640"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="599"/>
        </location>
        <ligand>
            <name>L-isoleucyl-5'-AMP</name>
            <dbReference type="ChEBI" id="CHEBI:178002"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="643"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="932"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="935"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="952"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="955"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU363035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF06827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF08264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="PRC94864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="969" mass="108311" checksum="5EA6D6CA56B324F3" modified="2018-07-18" version="1">MSKEKPSKSTYPVNMTETAFPMRGDLAKREPQWVKEWQDKKIYQRIRKAAQGRPSFVLHDGPPYANGEIHLGHAVNKILKDMIVKARTLAGFDAPYVPGWDCHGMPIEIQIEKLHGKHLPVAEVQTKARAYADVQIEKQKIDFKRLGVLGEWDNPYKTMAFGNEADEIRALGTILDKGYVYRGLKPVNWCFDCGSALAEAEVEYQDKRDPSIDVGFPFLQHDKIAAAFGLAKLPLQHGYCVIWTTTPWTIPSNMALNMHPEITYALVQTVRDGVPTLLILAQELVESSLKNYGLEGQILATCLGSALSLIEFKHPLAAMDPGYDRVSPVYLGEYVTIDSGTGIVHSAPAYGIEDYNSCKEHGIKDDDIISPVMGDGKYASWLPFFGGMTIWEASKPICDKLKEAGTLFKLVMFEHSYMHCWRHKTPIVYRATSQWFARMDVTPKDGGATLRETALAGVEATTFYPSWGKARLEGMIANRPDWTLSRQRQWGVPMAFFLHKETGQLHPRTAELLELIAKRVEKEGIEAWQNIEPADLLGDEAAMYVKNKDTLDVWFDSGCTHQTVLRGSHPTPVYKHAAPLIAGLTGPIGTAFPADLYLEGSDQHRGWFHSSLLTSSMLNRCAPYKALLTHGFVVDGEGRKMSKSLGNGVEPQTIFNTLGADILRLWVASSDYSGEITISDEILKRVTESYRRIRNTLRFLLANTSDFDATKDLVAVADMLEIDRYAVANMQALQNEVLAHYDQFEFHPVIAKLQGFCSEDLGGFYLDILKDRLYTSGANSAARRSAQSALWHITHSLLRLMAPTLSFTAEEAWKFFVSSSEFADSDETIFTQLFYTLPEVDGSEALLAKYNELRAIRLDVTKQLEEVRVTGEIGASLQADLTVRAAGTKYTVLKSLGDDLKFIFITSSAKVELVSSTEEEGVVVKASTEKKCERCWHYRADVGINTAHAGLCKRCVENLFEHGEARHFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4F7</accession>
    <name>A0A2S9H4F7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">FAD binding domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0065</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94870">
        <property type="protein sequence ID" value="PRC94870"/>
        <property type="gene ID" value="S2091_0065"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012951">
        <property type="entry name" value="BBE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08031">
        <property type="entry name" value="BBE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="SSF56176"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="2">
        <location>
            <begin position="101"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="595" mass="64326" checksum="2C6D7E17EC5F65B5" modified="2018-07-18" version="1">MSLATLLNGGLITRAVAAINSTATLWRRSRPSDASWPAKELWAELNQKVHGNLSKVDALFASCVLDQNSAACLDVKKNIRNPFYIGDQAGGTQVSGWLNAWRPEPSAYAIKAQTSADVVAGVNFARENKLRLVVKGAGHSYQGASNAADSLLIWTRAMNKVTLHEHFVPAGCEGIIAPVSAVTSEAGAVWIDLYNAVTTEAGRYVQGGGCADVGVAGLIQSGGFGSFSKGFGSASSHLLEAEIVTADGVLRVLNAQTNPELFWAIKGGGGGSWGVVTKVTLRTFELPEYFGAAWGKIKANSDTAFQRLITHFVDFYASQLFNPHWGEQVSFAPDNVLAISMICQGLNGQQAKQIWREFYDWVHASPNDFTIISELGAGESHARNWWKVDGNDSMIPDKREGAPKHHGWWEGDQGQVGAFLHGADSIWLPAALLKSEQRKQFEDALFQGSRHKKIELHFNKGLAGALPEKIFAATNTATNPTVCSSFALVIIAGGERPAYPGLATSNIDVDAASKSAHQVDLAAQALRNIVPNAGSYVSESNYFNPDWQQAFWGENYSRLQAVKKKYDPDGLFFVHHGVGSEEWSSDGFTRLVAQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4M3</accession>
    <name>A0A2S9H4M3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0124</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94929">
        <property type="protein sequence ID" value="PRC94929"/>
        <property type="gene ID" value="S2091_0124"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="54"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="347" mass="38362" checksum="B63C0A317C02F8C0" modified="2018-07-18" version="1">MKKWLKRISLSLLALLMLLVVSGAAVEQFYRHKYKNEFPPLGKLIDIGGRKIQIDCRGTGSPTVVFESGMDNLGSLSWSTVQEEVSKTTRACSYSRAGIMWSDPSDGAQNSKKIAADLNAVLTKAGEKAPFVLVAHSLGGPYAITYTKYYGNQVAGLVLIDPTPPDYEERCKLITKVNTFKLGLEQDKWLNYLTWTGAFRFSDPVDVKDPVVTQMETAYLPVSFDAIYKEELAFTQTTAESGTLRNLGTRPLIVLTSMKAYPAAALDELGITQQQGLQKKALWKSLHDDEAAWSSVSEHRLFADAGHYIHHDEPKAVVSAIQWVVQKVRGKIVEASLETPSTTSVKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4U5</accession>
    <name>A0A2S9H4U5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative acyl-CoA transferases/carnitine dehydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0199</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95004">
        <property type="protein sequence ID" value="PRC95004"/>
        <property type="gene ID" value="S2091_0199"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10540">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003673">
        <property type="entry name" value="CoA-Trfase_fam_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044855">
        <property type="entry name" value="CoA-Trfase_III_dom3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023606">
        <property type="entry name" value="CoA-Trfase_III_dom_1_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02515">
        <property type="entry name" value="CoA_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89796">
        <property type="entry name" value="SSF89796"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC95004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="412" mass="44941" checksum="A9D261323A0A1F9D" modified="2018-07-18" version="1">MTNSPQSASLEHIRVLDLTRVLAGPWCTQNLADLGADVIKVERPDVGDDTRSWGPPYAKDADGNNSTEAAYYLTANRGKRSITVDIATPEGQQVIRHLVMQSDVVIENYKVDQLKKYGLDYASLSALKPDLVYCSITGFGQTGPYAARAGYDFIIQGMGGLMSITGERDELPGGGPQKVGVAITDLMTGMYATIAVLAALTHRERTGVGQYIDLALLDVQVAMLANVGSNYLASGQAPKRWGNAHPNIVPYQTFATSDGHIIVAAGNDGQYRKFVQVGDYPELATDPRFISNPQRVEFRDTLVPILAEMVKKKSKEEWLELLESAGVPCGPINRLDEVFNDPQVQARECAIELPHPTAGNVRLVANPIKMSATPTRYNNAPPLLGQHTNHVLQELLGYSEQQLAQLRDKNVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H547</accession>
    <name>A0A2S9H547_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_0310</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95115">
        <property type="protein sequence ID" value="PRC95115"/>
        <property type="gene ID" value="S2091_0310"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="27"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="162"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="6">
        <location>
            <begin position="272"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="7">
        <location>
            <begin position="507"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="4">
        <location>
            <position position="558"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC95115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="653" mass="71660" checksum="FC6BACB6397C6D22" modified="2018-07-18" version="1">MLFLENPTLRNPRSMPLLRYSSLNQKILFSVISVALIMFSLVSALTVLHERNRMFNSADMDAHKDVNDNASVIAHDLWEFDNAALKASLKGLALSGSIIRAEVFDGDKVVATFSRLENTGSAEQADKIWAIDLMAPDDSKKIGSLRITESYAELRAVMANNVLAVIASELTKVGVLAAILFIIVHQLLTRHLKSLAHEIETANTLEVGSASTISLHRNNRRRDELDTLVDAINRFRQERAIAEQQTVLLARLSAQKEAAEVANRAKSRFLAAASHDLRQPIHALHLFLGTLKNLDLPLQAQRPLANVLRCTESIDEMFVSLLDVAKFDAGLIEPQISDFPIMTVLNRIRHECTLEANAKGLRLDVVPNSAWIRSDPLMVERILRNLVSNSIRYTASGKILVGCRRRPGNTLELAVYDTGIGIASDQQEKIFGEFYKAGFPDIGQPGLGLGLSIVDQLSKLLSAPLKLSSSEGMGSMFSVTFNLAQNTGIEHPPARPFNGNTNFDGCTVLVIDDDAAILEATRGLLEQWGCHVIIAEGINSAIKLLMQEAQLPNAMICDYRLRSKENGANAVAIICEEFNADIPAMLITADTSPTRIVQLKATGLPVLHKPLRDNELKIALTQLLFPSATPHFTGSKDSNLPDQTTDNVLLTHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H567</accession>
    <name>A0A2S9H567_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0313</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95118">
        <property type="protein sequence ID" value="PRC95118"/>
        <property type="gene ID" value="S2091_0313"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC95118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="114" mass="12433" checksum="8066EB83B52B9551" modified="2018-07-18" version="1">MSRFSPNVILQSSLSRKSMSWRNLVAVVTAFAFALLLSAALNHHHQTVLDTQDCPVCNAVVHKVSHSTPEVKLQQLVTILLYPAPLIARVIAVLYISPFILPPGCGPPVFHPAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5D2</accession>
    <name>A0A2S9H5D2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Membrane proteins related to metalloendopeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0390</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95195">
        <property type="protein sequence ID" value="PRC95195"/>
        <property type="gene ID" value="S2091_0390"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011055">
        <property type="entry name" value="Dup_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016047">
        <property type="entry name" value="Peptidase_M23"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01551">
        <property type="entry name" value="Peptidase_M23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51261">
        <property type="entry name" value="SSF51261"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M23" evidence="2">
        <location>
            <begin position="202"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC95195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="316" mass="34483" checksum="E1894569298D3F50" modified="2018-07-18" version="1">MQIIVMHPRFTRAKSIKITQKHVYLALFGLTLMVVVGSFLLSLLCLRLANYSESVRNLLPVEFSAPDSNSQAKYMKQNLAKMAIKLGEMQAQVMQLDALGERVQGLAGVKPEEFNFKNAPPRGGIAPSANAPTLSMSEFQTTLDALSIDLDRRSDFLNVVETTLMEYKVRSRLLPTSQPVNVTFNSSSFGWRLDPFTGQKAFHEGLDFPAPVGTPIVAAAGGVVITAEYHPQFGNMLEIDHGNDLVTRYAHCSRILAKVGDIVKRGQHVADIGTSGRSTGAHLHFEVLLKGRPQNPNKFLMAGANQANPANPVAAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5H3</accession>
    <name>A0A2S9H5H3_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Fructose-1,6-bisphosphatase class 1</fullName>
            <shortName evidence="5">FBPase class 1</shortName>
            <ecNumber evidence="5">3.1.3.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">fbp</name>
        <name evidence="9" type="ORF">S2091_0434</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>beta-D-fructose 1,6-bisphosphate + H2O = beta-D-fructose 6-phosphate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:11064"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:32966"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="EC" id="3.1.3.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="5">Binds 2 magnesium ions per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5 6">Belongs to the FBPase class 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.11" evidence="5"/>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95239">
        <property type="protein sequence ID" value="PRC95239"/>
        <property type="gene ID" value="S2091_0434"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042132">
        <property type="term" value="F:fructose 1,6-bisphosphate 1-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016051">
        <property type="term" value="P:carbohydrate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00354">
        <property type="entry name" value="FBPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01855">
        <property type="entry name" value="FBPase_class1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044015">
        <property type="entry name" value="FBPase_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000146">
        <property type="entry name" value="FBPase_class-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033391">
        <property type="entry name" value="FBPase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028343">
        <property type="entry name" value="FBPtase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11556">
        <property type="entry name" value="PTHR11556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00316">
        <property type="entry name" value="FBPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18913">
        <property type="entry name" value="FBPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF500210">
        <property type="entry name" value="FBPtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000904">
        <property type="entry name" value="FBPtase_SBPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00115">
        <property type="entry name" value="F16BPHPHTASE"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 6" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FBPase" evidence="7">
        <location>
            <begin position="5"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="domain" description="FBPase_C" evidence="8">
        <location>
            <begin position="198"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="116"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="91"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="113"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="115"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="116"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="208"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="274"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="280"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF18913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC95239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="334" mass="37043" checksum="064A9EC215C1E489" modified="2018-07-18" version="1">MKRISLTQYLVEEQRLNNNIPAELRLLIEVVARACKTISHAVGKGALGEVLGSAETENIQGEVQKKLDVLSNEILLEANEWGGHLAAMASEEMETIHLIPNRYPKGEYMLLFDPLDGSSNIDVNVSIGTIFSVLKAPEGMETPTEQDFLQAGSKQVAAGYALYGPQTLLVLTTGHGVNCFTLDREMGSWVLTQRDMKIPVDTQEFAINASNTRHWYPPVTRYVDEMLAGSTGPLGKNFNMRWIASMVADVHRILNRGGIFMYPADAREPDKAGKLRLMYEANPMSMLVEQAGGAATNGKQRMLDVQPEKLHQRVPVFLGSKNEVERVTAYHQET</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GS65</accession>
    <name>A0A2S9GS65_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4730</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000056">
        <property type="protein sequence ID" value="PRC90563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90563">
        <property type="protein sequence ID" value="PRC90563"/>
        <property type="gene ID" value="S2091_4730"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="61"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="101" mass="11584" checksum="280E64A1F26CA69B" modified="2018-07-18" version="1">MDANLEECKLDWIIAFFTCWFGMLYAAGSILSILMAYLICYPLGTSQILKKVGNAPKFVRYALAVCFITAGVILLYFAYGSTVFQYYFNMEKYPVELIQDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GS95</accession>
    <name>A0A2S9GS95_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Bifunctional protein PutA</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="2">Proline dehydrogenase</fullName>
                <ecNumber evidence="2">1.5.5.2</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="2">Proline oxidase</fullName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="2">Delta-1-pyrroline-5-carboxylate dehydrogenase</fullName>
                <shortName evidence="2">P5C dehydrogenase</shortName>
                <ecNumber evidence="2">1.2.1.88</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="2">L-glutamate gamma-semialdehyde dehydrogenase</fullName>
            </alternativeName>
        </domain>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_4712</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Oxidizes proline to glutamate for use as a carbon and nitrogen source.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>H2O + L-glutamate 5-semialdehyde + NAD(+) = 2 H(+) + L-glutamate + NADH</text>
            <dbReference type="Rhea" id="RHEA:30235"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58066"/>
            <dbReference type="EC" id="1.2.1.88"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>a quinone + L-proline = (S)-1-pyrroline-5-carboxylate + a quinol + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23784"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17388"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:60039"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="EC" id="1.5.5.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid degradation; L-proline degradation into L-glutamate; L-glutamate from L-proline: step 1/2.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid degradation; L-proline degradation into L-glutamate; L-glutamate from L-proline: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">In the C-terminal section; belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">In the N-terminal section; belongs to the proline dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.5.5.2" evidence="2"/>
    <dbReference type="EC" id="1.2.1.88" evidence="2"/>
    <dbReference type="EMBL" id="PUGF01000050">
        <property type="protein sequence ID" value="PRC90580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90580">
        <property type="protein sequence ID" value="PRC90580"/>
        <property type="gene ID" value="S2091_4712"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00261">
        <property type="reaction ID" value="UER00373"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003842">
        <property type="term" value="F:1-pyrroline-5-carboxylate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016620">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004657">
        <property type="term" value="F:proline dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006561">
        <property type="term" value="P:proline biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010133">
        <property type="term" value="P:proline catabolic process to glutamate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.550">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025703">
        <property type="entry name" value="Bifunct_PutA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005933">
        <property type="entry name" value="Delta1-pyrroline-5-COlate_DH-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029041">
        <property type="entry name" value="FAD-linked_oxidoreductase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041349">
        <property type="entry name" value="PRODH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024090">
        <property type="entry name" value="PRODH_PutA_dom_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024089">
        <property type="entry name" value="PRODH_PutA_dom_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024082">
        <property type="entry name" value="PRODH_PutA_dom_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002872">
        <property type="entry name" value="Proline_DH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01619">
        <property type="entry name" value="Pro_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14850">
        <property type="entry name" value="Pro_dh-DNA_bdg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18327">
        <property type="entry name" value="PRODH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000197">
        <property type="entry name" value="Bifunct_PutA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51730">
        <property type="entry name" value="SSF51730"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81935">
        <property type="entry name" value="SSF81935"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01238">
        <property type="entry name" value="D1pyr5carbox3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
        <property type="entry name" value="ALDEHYDE_DEHYDR_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2" id="KW-0520">NAD</keyword>
    <keyword evidence="1 2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-0642">Proline metabolism</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0678">Repressor</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="PRODH" evidence="8">
        <location>
            <begin position="17"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="domain" description="Pro_dh-DNA_bdg" evidence="7">
        <location>
            <begin position="71"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="domain" description="Pro_dh" evidence="6">
        <location>
            <begin position="192"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="domain" description="Aldedh" evidence="5">
        <location>
            <begin position="574"/>
            <end position="1014"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="793"/>
        </location>
    </feature>
    <feature type="active site" evidence="3 4">
        <location>
            <position position="827"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR000197"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000197-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF14850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF18327"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC90580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="1209" mass="132223" checksum="6661D1598E458543" modified="2018-07-18" version="1">MTQPFTFLHSEVLAQPTALRLAITNAYRPDEAHAVQTLLDQLTPFDHAPIQVLAKKLVKEVREQRTRASGVDALMHEFSLSSEEGVALMCLAEALLRIPDHQTVDRLIADKISKGDWRKHLGESPSLFVNAATWGLLVTGKLVSTNSERGLASALSKLISKGGEPLIRKGVDLAMRMLGNQFVTGQTIEEALKNSQENEKRGYRYSYDMLGEAALTAKDAAFYFSAYETAIHAIGRAAAGRGIKNGPGISVKLSALHPRYSRAQRSRVMEELLPGLKKLLVLAKQYNIGFNIDAEEADRLELSLDLIEALAFDADLAGFEGLGIVIQAYQKRCPYVLDFLIDLARRSKQKFMVRLVKGAYWDSEIKRAQVDGMSGYPVYTRKVYTDVSYLLCAQKLLAATDVIYPQFATHNALTLATIYTWAEQQKITDYEFQCLHGMGETLYDKVVGADKLNRPCRIYAPVGSHETLLAYLVRRLLENGANSSFVNQIVDESISLDSLVENPITVAEKLAGLPHSGIHLPLNLFGQERKNSAGFDFSNEQNLRVLSHEITQFSSHKWHAKPLLHGIANATTSHVITNPALHTDIVGHVIEANSHDLEIALQAAATHANEWNKTLPKDRAACLNKAADLLESNHVEFIALAIREAGKSFPNAVAEVREAVDFLRYYAAQILVISTTNALGPVVCISPWNFPLAIFLGEVSAALAVGNVVLAKPAEQTPLIAFRAIQLLHKAGIPTTALQFLPGRGETVGAKLVADIRVKGVIFTGSTEVAQLINQTLAKRSVAEQCEIPLIAETGGQNALIVDSSALPEQVVQDVLSSAFDSAGQRCSALRVLCLQHDIFDKTMQMLYGAMQELRIGNPDRLSIDIGPVIDLEAKNKLLSHIDELRPNAISFHQLPLSEECNEGHFVAPTVIEISSLAALKNETFGPVLHVIRYKRDELPQLIEQINQTGYGLTLGVHSRIDETIQYVIEHAHVGNIYVNRNIVGAVVGVQPFGGEGKSGTGPKAGGPLYLKRLQQHSNDQIHGHSVFERPSSDLLNTLLVWLKTHGHEKLAVFAEHYALTTPRKMSLVLPGPTGERNTLAFAPRGRIFCAASNVNTLLNQLAAVLATENIPVMSNATLSLIPASLPDIIKNAIQVSEVDALLSQVALIETSLLASLRPVIAFQEEWITTVVETSENEVVPLWRLLAERAVCINTTAAGGNASLMTLNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSB2</accession>
    <name>A0A2S9GSB2_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Poly-beta-1,6-N-acetyl-D-glucosamine synthase</fullName>
            <shortName evidence="4">Poly-beta-1,6-GlcNAc synthase</shortName>
            <ecNumber evidence="4">2.4.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_4690</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the glycosyltransferase 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="4"/>
    <dbReference type="EMBL" id="PUGF01000045">
        <property type="protein sequence ID" value="PRC90601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90601">
        <property type="protein sequence ID" value="PRC90601"/>
        <property type="gene ID" value="S2091_4690"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008375">
        <property type="term" value="F:acetylglucosaminyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043708">
        <property type="term" value="P:cell adhesion involved in biofilm formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023853">
        <property type="entry name" value="PGA_PgaC/IcaA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03937">
        <property type="entry name" value="PgaC_IcaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="302"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="339"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="370"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU364028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC90601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="442" mass="51638" checksum="21F7E9E14A7E3A56" modified="2018-07-18" version="1">MKLDILLFDFTFYYPLFMAYLWMIGGLTYYFRYEHKSHRIKDPLTLLKQTPLVSVIVPCFNEEENVAEVVDALSKLNYPNYEIICVNDGSTDHTGHLLDELTKIYPTLRVIHQAKNQGKAVGLDTAALVCQGEFLLCMDGDAILDRDVIPWMLQHFEEGHRVGAVTGNPRIRTRSTLLGRLQVGEFSSIIGLIKRTQRIYGRIFTVSGVVAMFRRRALLQVGFWSPDMLTEDIDISWKLQTHHWDIRFEPHALCWILMPETLAGLWKQRLRWAMGGIQVIKKYGHTLCSWRMRRMWLIYAEYLTSVFWAYSMALVLIIWSIGLLVHLPQRWQVTIVPGWHGVLIGTTCLLQILVSMLLDRHYDHKIFRHFFWMIWYPLAYWGLNMATTIWAVPRVFIRKRGKRAIWISPDRGLRTPTKRIEIRNPSDFVPPSSVVDTITKDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSI0</accession>
    <name>A0A2S9GSI0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">MFS transporter, metabolite:H+ symporter (MHS) family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_4632</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000039">
        <property type="protein sequence ID" value="PRC90682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90682">
        <property type="protein sequence ID" value="PRC90682"/>
        <property type="gene ID" value="S2091_4632"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004736">
        <property type="entry name" value="MHS_symport"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00883">
        <property type="entry name" value="2A0106"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="33"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="57"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="91"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="117"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="155"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="190"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="239"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="277"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="307"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="331"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="367"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="400"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="18"/>
            <end position="423"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC90682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="431" mass="46892" checksum="DCB9FB547FF2AF13" modified="2018-07-18" version="1">MTVQTNKIELDSKHRIFAIIGASSGNLVEWFDFYVYSFCSIYFASAFFPSGNSTTQLLNTAGVFAAGFLMRPIGGWLFGRIADKHGRRISMMISVLMMCGGSLMIACLPTYATIGAAAPILLLLARLIQGLSVGGEYGTSATYMSEVALKGRRGFFASFQYVTLIGGQLLAVLVLVILQQLLTTEQLKDWGWRVPFVIGAITALVALYLRKSLSETSSEESRKNQDAGTLVGLMKHKSALLTVIGFTAGGSLIFYTFTTYMQKYLVNTAGMNAKTASVVMTCALFSYMLMQPLFGALSDKIGRRSNMLIFGSLATLCTVPIMVALKDISNPYAAFGLILFALAIISFYTSIAGLIKAEMFPPEVRALGVGLSYAIGNALFGGSAEYVALWLKSIGWESSFYWYVTALCAIALIVSYRMRDTSKEGYLVHEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTA4</accession>
    <name>A0A2S9GTA4_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Glutamate racemase</fullName>
            <ecNumber evidence="2">5.1.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_4411</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>L-glutamate = D-glutamate</text>
            <dbReference type="Rhea" id="RHEA:12813"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:29986"/>
            <dbReference type="EC" id="5.1.1.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.1.1.3" evidence="2"/>
    <dbReference type="EMBL" id="PUGF01000033">
        <property type="protein sequence ID" value="PRC90918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90918">
        <property type="protein sequence ID" value="PRC90918"/>
        <property type="gene ID" value="S2091_4411"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008881">
        <property type="term" value="F:glutamate racemase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015942">
        <property type="entry name" value="Asp/Glu/hydantoin_racemase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001920">
        <property type="entry name" value="Asp/Glu_race"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004391">
        <property type="entry name" value="Glu_race"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21198:SF2">
        <property type="entry name" value="PTHR21198:SF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01177">
        <property type="entry name" value="Asp_Glu_race"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53681">
        <property type="entry name" value="SSF53681"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0133">Cell shape</keyword>
    <keyword evidence="6" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC90918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="262" mass="28428" checksum="BA7B16D947D1AECE" modified="2018-07-18" version="1">MKLHRPIGIFDAGIGSYAIVERVRARFPMQDIIYFADRASFPYGAKTPEELLESVRSATDYLCNEGCAAVVLASNAPSVVVLDALRAAVSVPVIGIFPPVREAIERSKSKQVAILGVRSLVSSDAMKIYANKNSTPESKVLLINASSLVDLVENFTFLNDPGATQEIVTRFILEVRRAAPEVDVMTMSSTHLPWLKQFFMSAAPDVLFLDPADAVLDELHSYTSNGAGYTRCVATETAELSLERFNAALLSLGTSHAAMLIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTB5</accession>
    <name>A0A2S9GTB5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phytanoyl-CoA dioxygenase (PhyH)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4358</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000032">
        <property type="protein sequence ID" value="PRC90957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90957">
        <property type="protein sequence ID" value="PRC90957"/>
        <property type="gene ID" value="S2091_4358"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008775">
        <property type="entry name" value="Phytyl_CoA_dOase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05721">
        <property type="entry name" value="PhyH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC90957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="364" mass="40663" checksum="8A5263641DD21420" modified="2018-07-18" version="1">MSTTPGNQDLAQFFKAGHFLLSDANSPDVMQRIVAAMNRLKVAYPFGFDHANGFGASTMKPRLAAPLPSDRAPTIIYHNVGFLEPDLLLPLHNPVIIDMVERVVGKDFYLSNVWLQVVPPHTGRMGYHKDEHGSISITMPLDTIGWNSGSTCLVPASHRNTPPPNFCMPDIMLEHGREAQLTGSLGDVVFFTPETWHGRAANQTDQPTCRLFYNFYSRASRDATRWSPCITADKVAEVAETLPVQYRHMLRIDPAKPKPTATQGRFTTWVMRNGSSSSAANLSAVLREYFYWRFTFNTPIVKDARGQSLPAYRTTITESEQFSLLEYICHLNAMRTVKNGVRMTLNYWMSVFGIGGRAVAKGGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTC3</accession>
    <name>A0A2S9GTC3_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_4352</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="PUGF01000032">
        <property type="protein sequence ID" value="PRC90951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90951">
        <property type="protein sequence ID" value="PRC90951"/>
        <property type="gene ID" value="S2091_4352"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014265">
        <property type="entry name" value="Sig_transdc_His_kin_PEP-CTERM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02916">
        <property type="entry name" value="PEP_his_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="41"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="67"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="105"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="133"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="164"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="237"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="262"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="5">
        <location>
            <begin position="482"/>
            <end position="684"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC90951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="694" mass="78449" checksum="ED6858BBDFF7C458" modified="2018-07-18" version="1">MHSPMLSNVAILSYGLAAAAYLVLSGMLLWKWRGRLRWMPLMVAAGITTVWAASIALNAKFGIPTGFWINSLEVMRSASWIIFLLMLLQPLERETPQSLFKEKPYVVLIGLFLLLLLAATMLTNVGLMVRFGGIVNITGRVALAVIGMLLLEQLFRNTTEHQRWSVKFACLGLAALFVYDFYLYADAMLFHAINGEILAARGFVNALSVPLLMISLNRDPKWTLGILVSRRVLFHSATLLGAAAYLLTMAAAGYYIRFFGGQWGTVLQVFFLFGAVILLFILLFSGSVRSWLRVFISKHFYNYNYDYRDEWIRFTRVLSESEPGLGERAIQAVAQLVESGAGTLFISRESGYCEPVAQWCAQFESQAEALNSPFCRFLQEKQWVINLTDYKLHPEKYDDISVPQWLLDFPRAWLVLPLILHGRLFGFIMLEQARSKFDVNWEVLDLLKIATSQAASYLAEQESANALMVARQFESFNRMSTFMVHDLKNLVAQLSLLTANAEKHQHNPEFQKDMLDTVDHSVQKMKFLLQKLSRGFEVESLSALAMDELLQRAVASKSPYEPKPVLQIEQPDIAVYANRERLERVIGHIIQNAIDATPRDGDIKIKLGLDGRDALIEIEDNGVGMTEEFIREKLFSPFVSTKVAGMGIGVFETREYIQQLGGRLEVQSRPESGTRFKITLPVYSTLEQVNTQIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTD5</accession>
    <name>A0A2S9GTD5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Mu-like prophage FluMu protein gp41</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4278</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000031">
        <property type="protein sequence ID" value="PRC90982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90982">
        <property type="protein sequence ID" value="PRC90982"/>
        <property type="gene ID" value="S2091_4278"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019289">
        <property type="entry name" value="Phage_tail_Gp41_put"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10109">
        <property type="entry name" value="Phage_TAC_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC90982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="108" mass="11726" checksum="3A0B2A2547CE9852" modified="2018-07-18" version="1">MNTAQHATSNANGIYVTITLDEAIQRGESLITEIQLRKPKAGELRGVSLVELAQLDVTALQKVLPRITQPTLTNHEVNNLDLADLMSLGAEVAFFLAKKADRNMASPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTP1</accession>
    <name>A0A2S9GTP1_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">NAD kinase</fullName>
            <ecNumber evidence="5">2.7.1.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">ATP-dependent NAD kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">nadK</name>
        <name evidence="6" type="ORF">S2091_4188</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>ATP + NAD(+) = ADP + H(+) + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:18629"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.23"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the NAD kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.23" evidence="5"/>
    <dbReference type="EMBL" id="PUGF01000029">
        <property type="protein sequence ID" value="PRC91092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91092">
        <property type="protein sequence ID" value="PRC91092"/>
        <property type="gene ID" value="S2091_4188"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003951">
        <property type="term" value="F:NAD+ kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019674">
        <property type="term" value="P:NAD metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006741">
        <property type="term" value="P:NADP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00361">
        <property type="entry name" value="NAD_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017438">
        <property type="entry name" value="ATP-NAD_kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017437">
        <property type="entry name" value="ATP-NAD_kinase_PpnK-typ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016064">
        <property type="entry name" value="NAD/diacylglycerol_kinase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002504">
        <property type="entry name" value="NADK"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01513">
        <property type="entry name" value="NAD_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111331">
        <property type="entry name" value="SSF111331"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 5 6" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 5" id="KW-0520">NAD</keyword>
    <keyword evidence="3 5" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5" id="KW-0808">Transferase</keyword>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="76"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="76"/>
            <end position="77"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="150"/>
            <end position="151"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="178"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="180"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="191"/>
            <end position="196"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="215"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="249"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC91092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="300" mass="32471" checksum="F24795A6604CABC4" modified="2018-07-18" version="1">MTTSPAVAKTIALVGKYSAAGIAKDLLSLAHFLVEAGHTVVLEQETATNLSLTEFTIMPPAQIGQHADVAIVLGGDGTMLGIARQLAPYQIPLIGINQGRLGFMTDIPIEQMYTALSEILAGNHQLEQRSLLEGVVIRDGQEITSGLAFNDIVVARGAGSGMVELKVTVDNHFMYNQRSDGLIISTPTGSTAYALSAGGPLMHPNLAGIVFVPIAPHALSNRPIVVSDSSKIIIEISAVREASVNFDMQSFAHLMVGDQIHIQRSKHVICFLHPKEWNYYHTLRDKMHWNEYPTVNGNLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTR7</accession>
    <name>A0A2S9GTR7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">EamA-like transporter family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_4216</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000029">
        <property type="protein sequence ID" value="PRC91120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91120">
        <property type="protein sequence ID" value="PRC91120"/>
        <property type="gene ID" value="S2091_4216"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="29"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="91"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="118"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="141"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="170"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="203"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="238"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="271"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="295"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="32"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="172"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="325" mass="34542" checksum="398705500D00E130" modified="2018-07-18" version="1">MPGSNCIQLQPTTPFAPKQPGEFLKTTDFIRLICLSAIWGASFLFMRIIVPVLGVLPSSFIRVFFASIGLLIIIAALQFSIHFKGKLKSLLLLGIFSSGIPVLMYSIAALVLPAGYSAIFNATTPLMGILIGALFFSEKLTIAKAAGVLFGLAGVAVLTRTGPVALNGQVLLGAAACLVATSCYGLAGFLTKRWISERGGLDSRLVALGTQLGATALLLPPFIFSVSTNPPATWGGTGVWLAIAGLGFICTSLAYIMYFRLIADIGPVKSLTVTFLIPPFGVFWGWIFLGEQITWAHLGGGMLIAVALWLVLMQHKPRSVSNVKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTU7</accession>
    <name>A0A2S9GTU7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Purine-cytosine permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_4156</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the purine-cytosine permease (2.A.39) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000028">
        <property type="protein sequence ID" value="PRC91155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91155">
        <property type="protein sequence ID" value="PRC91155"/>
        <property type="gene ID" value="S2091_4156"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001248">
        <property type="entry name" value="Pur-cyt_permease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026030">
        <property type="entry name" value="Pur-cyt_permease_Fcy2/21/22"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31806">
        <property type="entry name" value="PTHR31806"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02133">
        <property type="entry name" value="Transp_cyt_pur"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002744">
        <property type="entry name" value="Pur-cyt_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="36"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="66"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="105"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="142"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="169"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="201"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="240"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="277"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="301"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="333"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="361"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="408"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="440"/>
            <end position="457"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR002744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC91155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="489" mass="52891" checksum="3ACE6787FFC7E6DD" modified="2018-07-18" version="1">MALDSSGNTQKKSLIETRSIDYIPESERHGHLLSQFTLWFGTNLQITAIVTGALAVVLGGDVFWSLFGLLIGQILGGSVMALHAAQGPHLGLPQMISSRVQFGVYGAVIPIVLVCVLYVGFSATGTVLAGQSIAKLLDTTNSTGILLFGALIVVLTLFGYRLIHLIGRAASVIGIIAFVYLFSSLVMQFNLTELLMNNRHFTLAHFLLAISLSASWQIAYGPYVADYSRYLPSTISPIKTFLAVGGGSVLGTQISMTLGVFAAALAGKQFAGNELNYIVSLGGTGIIASFLYFSIIFGKIIATTLNSYGSFMSIATIVSGFRGNRQISPVVRFIYIFSMVGLATGLALAGQYSFLTIFKSFILFLLAFFTPWSAINLVDYYWVTKGRYDLKALSDPNGRYGAWNKIGISTYVIGVVIQMPFLATGFYTGPMVAHLGDTDISWIIGLVIPGILYYFAMKKWPYEIPEKLILPDAVCVDEAVFEGSELQAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GU70</accession>
    <name>A0A2S9GU70_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4043</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000026">
        <property type="protein sequence ID" value="PRC91258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91258">
        <property type="protein sequence ID" value="PRC91258"/>
        <property type="gene ID" value="S2091_4043"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015727301" evidence="1">
        <location>
            <begin position="22"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="144" mass="16073" checksum="69C16C493E4A6CE9" modified="2018-07-18" version="1">MKKFLVLIGLVLTGFVMTATAQEAKSYKEGQVTVLTYVKVKPGKFDEYMKWLATTGKAFREAEIKAGILLSYHVYSANPRTPREPDLILSSTYPNMAALDKDDDEDALAGKTMGNRATRNKAAEDREALREIQGSEIIRELVLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUC1</accession>
    <name>A0A2S9GUC1_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Cell division protein ZipA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_4003</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the ZipA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000025">
        <property type="protein sequence ID" value="PRC91332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91332">
        <property type="protein sequence ID" value="PRC91332"/>
        <property type="gene ID" value="S2091_4003"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090529">
        <property type="term" value="P:cell septum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1400.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007449">
        <property type="entry name" value="ZipA_FtsZ-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036765">
        <property type="entry name" value="ZipA_FtsZ-bd_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04354">
        <property type="entry name" value="ZipA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00771">
        <property type="entry name" value="ZipA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64383">
        <property type="entry name" value="SSF64383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1" id="KW-0132">Cell division</keyword>
    <keyword evidence="2" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="2 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="domain" description="ZipA_C" evidence="5">
        <location>
            <begin position="220"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="56"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC91332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="362" mass="39308" checksum="44F62C2C1427B8AF" modified="2018-07-18" version="1">MTDLNLSLWGAGCAVIVGVIGYNFWQEYKAKKNVERAFGHNQDDVLMKSDKQAAVNSGNSTTAKVRQEPSLDDNSTIQPSYHAESVDVDLDKTVGIIEVPLPVDDFIDCVIPMEFENPLRGDKMLSEIQSFRRVGNKPVHFIGINADGKREIITHANSYNQMIAGVQLVSRSGALNELEYSELVMKLREIADNLNAFPDIPDMKHVMDAGRDLHLFVTEHDAQLSVNVQSKGAPWGISTLLAALEKLGFDARPDGRLAMLDGDGGSLFTLSTNCGVADQVTSRITLLLDVPCVAPARGGFVAMVSCAKSLALRLGGSLVDDGNQLLNDATLDQIQEQVEVFYSAMQAAEIPAGSIRAVRIFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUC5</accession>
    <name>A0A2S9GUC5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4006</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000025">
        <property type="protein sequence ID" value="PRC91335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91335">
        <property type="protein sequence ID" value="PRC91335"/>
        <property type="gene ID" value="S2091_4006"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="126" mass="14257" checksum="5E13A8AA09082F20" modified="2018-07-18" version="1">MRPTNMNKETAIQIANESMRSNALNSGNTQFSQVVRNVDDEGWWMNIPLTSFRKECHFLLCSEKAGIIRHLVLKPSAILSPATKFRIKDGIADIFISAANPKRLADKLAGGTKYSFNKHLVDEYRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUM2</accession>
    <name>A0A2S9GUM2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphoesterase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3946</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000024">
        <property type="protein sequence ID" value="PRC91401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91401">
        <property type="protein sequence ID" value="PRC91401"/>
        <property type="gene ID" value="S2091_3946"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007312">
        <property type="entry name" value="Phosphoesterase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31956">
        <property type="entry name" value="PTHR31956"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04185">
        <property type="entry name" value="Phosphoesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015394221" evidence="1">
        <location>
            <begin position="40"/>
            <end position="605"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="605" mass="63048" checksum="B87FDF760BE2AE00" modified="2018-07-18" version="1">MKKTLKQRTAVHSSLRSSLRCSALAMMAASMFCAVSAQAQTSQNLVVNGNAEAGACTNDWSAVTTVPGWNVISGNPSIACYSIASFSTPNSAANGNAFFADGPYGDSSMSQTVNLASAASAIDGGSVTFNLSAWLGGYTVYSGAGVVTVTFYNAAGQALSGGTQLSGDTPTARGSVNKFLATSGTGYVPVGARSAQVLVQFVNTTGVTYNVGYADNISLTLSTPVTPAVLTPPVSAVPAFDHVFMVMMENTSYNQVIGNTSSAPFINSLANQGTLLANYSGVYHPSDENYMAIAGGNTFVQGAIYFPNIKVTSKHLGDQLEAVGKTWKAYEQGMGSPCNLTTNNDKYYEPDDAPFINFTNISGNPTRCAAHLFDTTQLTTDLASAATTPNFSWIAADDYYDGEASGNGSTTSLQTQDGWLKQTLQPIFNSPAWKNQRSLLILTWDESSVSGTNHVGTILVGSNGLVNNTISNTSYNHYSVGRTIESALGIAPMTANDQYATPINDAFVVAPAVTLTASTTSISSSGSIAFNYSAPPVSQNSTNWIGIYPAGAVPGSGSSTTWQYVPNPSGQATFSGLSAGSYFAEYFYNGGYTALSAPVAFTVTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUN8</accession>
    <name>A0A2S9GUN8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Mce related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3838</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000023">
        <property type="protein sequence ID" value="PRC91423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91423">
        <property type="protein sequence ID" value="PRC91423"/>
        <property type="gene ID" value="S2091_3838"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003399">
        <property type="entry name" value="Mce/MlaD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02470">
        <property type="entry name" value="MlaD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MlaD" evidence="2">
        <location>
            <begin position="9"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="246"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="277" mass="29811" checksum="8D7BE6FEC27398D2" modified="2018-07-18" version="1">MYLAIEDESVAGLNVNAPVKYNGVDVGKVRNIQLDPSNPDRVNLLFAINHNTPIREDTVAVLKTQGLTGIAYVELSSTAHNSPLLHKTAGYEYPVIRTKPSLGARLENVLTTVLASLDSTSKHINSILSDQNQENFKNTLSDLATIAHTIALRKDAIDHGLRNADLTLNNTTRLTAQAGPVIDQIGRSAESISTMGKEVSRTSINAGKSLNSIGSDLKGFTDVSLPELDRLIGELNALSASMRRLSEQTERNPNSLLFGITPVPDGPGETPTVVRKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUP4</accession>
    <name>A0A2S9GUP4_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_3870</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="PUGF01000023">
        <property type="protein sequence ID" value="PRC91455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91455">
        <property type="protein sequence ID" value="PRC91455"/>
        <property type="gene ID" value="S2091_3870"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3 4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PAC" evidence="8">
        <location>
            <begin position="164"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="6">
        <location>
            <begin position="247"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="7">
        <location>
            <begin position="495"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="64"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="206"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="4">
        <location>
            <position position="545"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC91455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="618" mass="68568" checksum="BB95D3CED49C5620" modified="2018-07-18" version="1">MNLENGIPNPDEKVKNLELFPEGSNAAAAYLLQRQHAEARLQQHAALSQEEVTILSPEVSRHLLHELRVHQIELEMQNEELRESQVALDAARDRYFDLYDLAPVGYCTISEKGLIRQANLAAASLFGVMRGTLLKQPLSRFISRENQDTYYLHRKKLVETGEPQSFEMQMVKEDATPFWAHLTMTIAQDADGAAELRVVLNDVTERKHAEDERALLQQDLQDKNAELERARVVAEKANQAKSDFLSNMSHELRTPLHAILGFAQLLGTGAPVNSTPLTLDQQQSVDQILKAGWHLLELVNDILDLAVIEAGKIGLSIEAVSLTEIIRECKAMAAPLAQRRGIEIIFPSEEICCFAQVDRIRIKQVLINLLSNAIKYNRPNGTVTLTVKSGVNSERSIRICVADTGAGLRQDELLQLFQPFNRLGQDMNAEEGTGIGLVVCKRLIELMSGTIGVESIVGKGSVFWIELALVDSPDNIKPLQINTENIAQLVTKSHTLLYVEDNLANLKLVEAIIARQPHIRLLSAPNGNSGIVMARDFLPDIILMDIDLPDISGFTVLKMLAEDATTAHIPVIALSANAMPHNIEQGLKAGFFQYMTKPIKIDELMKTLNKATDNTFGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUV6</accession>
    <name>A0A2S9GUV6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Flagellar protein FliT</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3769</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000022">
        <property type="protein sequence ID" value="PRC91491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91491">
        <property type="protein sequence ID" value="PRC91491"/>
        <property type="gene ID" value="S2091_3769"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008622">
        <property type="entry name" value="FliT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05400">
        <property type="entry name" value="FliT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0966">Cell projection</keyword>
    <keyword evidence="2" id="KW-0969">Cilium</keyword>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2" id="KW-0282">Flagellum</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="112" mass="12838" checksum="977A7D7C74B6BE79" modified="2018-07-18" version="1">MTSQELMTIYENVASLTDQMVGAAQSNNWTLLAKLEEKCSLQVQAIKDNDVPVVLANEQREKKVCVINKILADDRKIRDITEPRMAQLSELMKSSSSQRKLFRAYQLDHRRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUW0</accession>
    <name>A0A2S9GUW0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Glutamate decarboxylase and related PLP-dependent protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_3778</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5 6">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the group II decarboxylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000022">
        <property type="protein sequence ID" value="PRC91500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91500">
        <property type="protein sequence ID" value="PRC91500"/>
        <property type="gene ID" value="S2091_3778"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016831">
        <property type="term" value="F:carboxy-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:cellular amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010977">
        <property type="entry name" value="Aromatic_deC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002129">
        <property type="entry name" value="PyrdxlP-dep_de-COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021115">
        <property type="entry name" value="Pyridoxal-P_BS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00282">
        <property type="entry name" value="Pyridoxal_deC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00800">
        <property type="entry name" value="YHDCRBOXLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00392">
        <property type="entry name" value="DDC_GAD_HDC_YDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="4 6" id="KW-0456">Lyase</keyword>
    <keyword evidence="5 6" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="5">
        <location>
            <position position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR602129-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC91500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="467" mass="50748" checksum="E4B628E65A15A41D" modified="2018-07-18" version="1">MLEDMLNYAEQLRERPVWQPIPQSIHDRFQENLPQQGTELALLHQRFLTEIMPYSIGNAHPGFMGWVQGGGTPVGMVAEMLAAGLNANVGGREQVPISVEKQILRWMRELFQFPETANGLFVTGTSLANLIAVLIARTTHLGVQARRDGIAHGDKKLTAYTSAGAHGSVSQAMDLAGFGTAALRPIPMNAAYQLDLDKLRAAIQTDKAAGFEPFLIIGSAGTVDVGAIDDLTALANIAQAENCWFHVDGAYGALGMLSPQIAPRLCGIERASSIAFDFHKWGQVPYDAGYILVRDGAQQLATFSAPAHYLKRETRGMAAGSPWPCDLGPDLSRGFRALKTWFTIATFGAEKLGQIINNTCELAQYLKQRVEQEPQLELLAPVNLNIVCFRYVGTSKLSASDLNNLNTELVIRLQESGVVAPSSTLIQHQFAIRAAIVNHRTTRLDMDNLINTTLLLGGELGIAATHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUW9</accession>
    <name>A0A2S9GUW9_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="8 19">Adenosylcobinamide-GDP ribazoletransferase</fullName>
            <ecNumber evidence="7 19">2.7.8.26</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="18 19">Cobalamin synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="17 19">Cobalamin-5'-phosphate synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19" type="primary">cobS</name>
        <name evidence="20" type="ORF">S2091_3803</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="16 19">Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 19">
            <text>adenosylcob(III)inamide-GDP + alpha-ribazole 5'-phosphate = adenosylcob(III)alamin 5'-phosphate + GMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23560"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57918"/>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
            <dbReference type="ChEBI" id="CHEBI:60487"/>
            <dbReference type="ChEBI" id="CHEBI:60493"/>
            <dbReference type="EC" id="2.7.8.26"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 19">
            <text>adenosylcob(III)inamide-GDP + alpha-ribazole = adenosylcob(III)alamin + GMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16049"/>
            <dbReference type="ChEBI" id="CHEBI:10329"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18408"/>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
            <dbReference type="ChEBI" id="CHEBI:60487"/>
            <dbReference type="EC" id="2.7.8.26"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3 19">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="5 19">Cofactor biosynthesis; adenosylcobalamin biosynthesis; adenosylcobalamin from cob(II)yrinate a,c-diamide: step 7/7.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="19">Cell membrane</location>
            <topology evidence="19">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6 19">Belongs to the CobS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.26" evidence="7 19"/>
    <dbReference type="EMBL" id="PUGF01000022">
        <property type="protein sequence ID" value="PRC91525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91525">
        <property type="protein sequence ID" value="PRC91525"/>
        <property type="gene ID" value="S2091_3803"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00148">
        <property type="reaction ID" value="UER00238"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051073">
        <property type="term" value="F:adenosylcobinamide-GDP ribazoletransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008818">
        <property type="term" value="F:cobalamin 5'-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009236">
        <property type="term" value="P:cobalamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00719">
        <property type="entry name" value="CobS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003805">
        <property type="entry name" value="CobS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34148">
        <property type="entry name" value="PTHR34148"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02654">
        <property type="entry name" value="CobS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00317">
        <property type="entry name" value="cobS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 19" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10 19" id="KW-0169">Cobalamin biosynthesis</keyword>
    <keyword evidence="13 19" id="KW-0460">Magnesium</keyword>
    <keyword evidence="15 19" id="KW-0472">Membrane</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11 19" id="KW-0808">Transferase</keyword>
    <keyword evidence="12 19" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="14 19" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="47"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="120"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="148"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="190"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="216"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00010561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00013200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00015850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00025228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00032605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00032853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="PRC91525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="270" mass="29383" checksum="023705F3B354F657" modified="2018-07-18" version="1">MSFFTKAGAWSLQQVRLFFIALQFFTRIQIPQWVGFEADWLHHAARYFVLVGLVVASVASAVYVCAALFLPHLVAVLLSTIASIYLTGAFHEDGFADVCDGFGGASSKERVLEIMKDSRIGAYGAIGIILMLALKCSVLFYLPAPALIATLFIGHALSRLAATTLIWRLSYVRAEGKAKPLAERISTGEYITAMLTALLPMMICGVTGWLSWFSMLIGVVAVALAGLWLSALFVRRIGGYTGDCLGAVQQFSEVAFYLAILATLRTSFYP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVE0</accession>
    <name>A0A2S9GVE0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NUDIX domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3621</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000020">
        <property type="protein sequence ID" value="PRC91683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91683">
        <property type="protein sequence ID" value="PRC91683"/>
        <property type="gene ID" value="S2091_3621"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="2">
        <location>
            <begin position="44"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="188" mass="21499" checksum="9C8A26A676AD12FB" modified="2018-07-18" version="1">MTDLDKHLKETFISGEQVYDGHFLKIQRDKVALPDGKSTFREYIKHPGAVVILPLFEDGTVLLERQYRYPLNQVFIEFPAGKIDLDEDPLDCAKRELLEETGYTANSWQFVCTIHNAIAYADEHLEIFLARDLHPGQSNLDDGEFLETYRAPLTELLDAVKNGQVTDVKTIIGAFWLEKIQSGLWLKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVL1</accession>
    <name>A0A2S9GVL1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3493</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000019">
        <property type="protein sequence ID" value="PRC91738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91738">
        <property type="protein sequence ID" value="PRC91738"/>
        <property type="gene ID" value="S2091_3493"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="51" mass="5835" checksum="F4A0176461FBD8F0" modified="2018-07-18" version="1">MTQQTDNQHKNPGKTFPSPLPDAKKQKQKEEQNEVVGRHKNDGQKDHKGAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVP0</accession>
    <name>A0A2S9GVP0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ABC-type antimicrobial peptide transport system ATPase component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_3523</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000019">
        <property type="protein sequence ID" value="PRC91768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91768">
        <property type="protein sequence ID" value="PRC91768"/>
        <property type="gene ID" value="S2091_3523"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03255">
        <property type="entry name" value="ABC_MJ0796_LolCDE_FtsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017911">
        <property type="entry name" value="MacB_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-1278">Translocase</keyword>
    <feature type="domain" description="ABC transporter" evidence="7">
        <location>
            <begin position="6"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="42"/>
            <end position="49"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC91768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="248" mass="26114" checksum="DE64F51AE7ECD667" modified="2018-07-18" version="1">MLRPPIILHDVVKSYETPSGSFMALKKVSLEIQQGEFIAVVGKSGSGKTTLLNVIAGIDRPSSGSVTVAGQALQELSEHQLSTWRGTTVGIVFQFFQLLPTLTALENVMLAMDFCKKYPARERRARAMELLAKVGVSEQSNKLPATLSGGQQQRVAIARALANAPTLIVADEPSGNLDSVTAATVLGLLRTLADSGTTVVVATHDKDIAALSDRSIYVADGKLESVSASASVSSAQPLHPIHLQQGAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVV5</accession>
    <name>A0A2S9GVV5_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Flagellar biosynthesis protein FlhA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">flhA</name>
        <name evidence="8" type="ORF">S2091_3409</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000018">
        <property type="protein sequence ID" value="PRC91853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91853">
        <property type="protein sequence ID" value="PRC91853"/>
        <property type="gene ID" value="S2091_3409"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044780">
        <property type="term" value="P:bacterial-type flagellum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.540">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042194">
        <property type="entry name" value="FHIPEP_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042193">
        <property type="entry name" value="FHIPEP_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042196">
        <property type="entry name" value="FHIPEP_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025505">
        <property type="entry name" value="FHIPEP_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006301">
        <property type="entry name" value="FlhA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001712">
        <property type="entry name" value="T3SS_FHIPEP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30161">
        <property type="entry name" value="PTHR30161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00771">
        <property type="entry name" value="FHIPEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005419">
        <property type="entry name" value="FlhA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00949">
        <property type="entry name" value="TYPE3IMAPROT"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01398">
        <property type="entry name" value="FlhA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00994">
        <property type="entry name" value="FHIPEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1005">Bacterial flagellum biogenesis</keyword>
    <keyword evidence="7" id="KW-1006">Bacterial flagellum protein export</keyword>
    <keyword evidence="3 7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0966">Cell projection</keyword>
    <keyword evidence="8" id="KW-0969">Cilium</keyword>
    <keyword evidence="8" id="KW-0282">Flagellum</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="21"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="45"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="116"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="208"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="250"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="284"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU364093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC91853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="697" mass="74884" checksum="E6A35E2EBC549201" modified="2018-07-18" version="1">MDSLKLPAWLSGLDFLNSRTLTAPLLIVMILAMMVLPLPAFVLDIFFSFNIALAVIVLLTSFYTVKPLDFMVFPTVLLVSTMLRLSLNVASTRVVLTEGHTGPDAAGKVIEAFGHFLIGGNYAVGIVVFVILTIINFTVVTKGAGRIAEVGARFALDAMPGKQMAIDADLNAGLIAEQEARRRRTEVAQEAEFYGAMDGASKYVRGDAIAGIMVTIINIVGGLVVGMAQHDLDFSQALKLYTLLAIGDGLVAQIPSLIISTAAGIVVSRVASDKNIGDQLIGQLFAKPQVLIITACIIGGMGIIPGMPHFAFLFFAAVLGAGGYFLRKRTQLAAQEPEAAPAVVAPVESEEATWQDVLPVDTLGLEVGYRLIPMVDKAQGGELLKRIKGIRKKFAQDIGFLSPPVHIRDNLELKPTSYTISLKGVEMGAGEAFAGQYLAINPGMVSGTLEGRPTIDPAFGLPAVWIDANRRESAQAMGYTVVDAGTVVATHLNHLITTHAAELLGRHEVQQLLDYVAKDAPKLIEDLIPKLLPLPSFQKVLQNLLSEGVHIRDMRSIVETLSEHVIQTQDTNELTSLVRVALGRAIVQQLFPGTNELSVMSLDTHLERLLMQALQNGSPDGIGLEPGLADTILSQTELASRHQEQMGLTPVLVVPAALRLLLARFLRRSLPQLRVLSHAEVPESKTIKVTSLVGGQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GW05</accession>
    <name>A0A2S9GW05_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribonuclease R</fullName>
            <shortName evidence="6">RNase R</shortName>
            <ecNumber evidence="6">3.1.13.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rnr</name>
        <name evidence="9" type="ORF">S2091_3459</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates.</text>
            <dbReference type="EC" id="3.1.13.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the RNR ribonuclease family. RNase R subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.13.1" evidence="6"/>
    <dbReference type="EMBL" id="PUGF01000018">
        <property type="protein sequence ID" value="PRC91903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91903">
        <property type="protein sequence ID" value="PRC91903"/>
        <property type="gene ID" value="S2091_3459"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008859">
        <property type="term" value="F:exoribonuclease II activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01895">
        <property type="entry name" value="RNase_R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011129">
        <property type="entry name" value="CSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040476">
        <property type="entry name" value="CSD2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013223">
        <property type="entry name" value="RNase_B_OB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001900">
        <property type="entry name" value="RNase_II/R"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022966">
        <property type="entry name" value="RNase_II/R_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004476">
        <property type="entry name" value="RNase_II/RNase_R"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011805">
        <property type="entry name" value="RNase_R"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022967">
        <property type="entry name" value="S1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17876">
        <property type="entry name" value="CSD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08206">
        <property type="entry name" value="OB_RNB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00773">
        <property type="entry name" value="RNB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00575">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00357">
        <property type="entry name" value="CSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00955">
        <property type="entry name" value="RNB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00358">
        <property type="entry name" value="3_prime_RNase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02063">
        <property type="entry name" value="RNase_R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01175">
        <property type="entry name" value="RIBONUCLEASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 6" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="4 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 6" id="KW-0540">Nuclease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="S1 motif" evidence="8">
        <location>
            <begin position="656"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="745"/>
            <end position="825"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC91903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="825" mass="90733" checksum="A5C8DD0B4AAF6098" modified="2018-07-18" version="1">MSKHTYSIPSREDILGVLRSNAAKHDSQQIAAALGVPPDEHDGLMRRINAMERDGQVKLDKEGFYHVQSKDNFIAGKVSSHRDGYGFLVPDDGSDDVYLPEREMQRVLNGDRVLVRVVGTDRRGRLEGGIVEVLDRANTHIIGRLLNENGAWVIAPEDKRISQDIMLAGPPGQAKAGQVVSVQLTEQPTRYAQPVGKIVEVLGDVDDPGMEIEIAVRKFGVPHIFSEAALKAASKLPGEVKPADLQDRVDLRDIPMVTIDGEDARDFDDAVYCEPVKIGRIAGYRVIVAIADVSHYVKPNDAIDGDAILRSTSVYFPRRVIPMLPEKLSNGLCSLNPDVDRLTLVCDLVITAHGEVKGYQFYPAVIHSAARFTYTEVAAILGNTKGPEAHKRAALVPHLLHLQEAYHALLEARQLRGAIDFETTETYIVCNAAGKIEKILPRTRNDAHKLIEECMLAANVCAADLLIRHKQPGTYRIHASPSKEKLNQVRTYLKQLGLNLNGGDKPSASDYADLMKKIKGRLDAPILQTMLLRSMQQAVYSPDNIGHFGLSYDAYAHFTSPIRRYPDLLTHRAIKAILLGKKYEPTGIDVGSLNSTISNAARKQQIVDKADGKQKKDPTIWDALGVHCSANERRADEASRDVEAWLKCYYIRNKLGEEFTGTISGVTQFGIFVQLDSLYIEGLVHVTDLGADYFQYDDARHELRGERTGKRYQLTDRVTVQVTRVDLDARKIDLCLVQPGAPRAVPGAKTSKNAKSGSGAVVKAKSNAANYDEVVPSKVKARHGAAEGKPARPSKAASVAKREKNVSGRSKGNTKVTGKSSLKKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GW26</accession>
    <name>A0A2S9GW26_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Alternate F1F0 ATPase, F1 subunit gamma</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_3265</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ATPase gamma chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000017">
        <property type="protein sequence ID" value="PRC91923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91923">
        <property type="protein sequence ID" value="PRC91923"/>
        <property type="gene ID" value="S2091_3265"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045261">
        <property type="term" value="C:proton-transporting ATP synthase complex, catalytic core F(1)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12151">
        <property type="entry name" value="F1-ATPase_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017709">
        <property type="entry name" value="Alt_ATP_synth_F1_gsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035968">
        <property type="entry name" value="ATP_synth_F1_ATPase_gsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000131">
        <property type="entry name" value="ATP_synth_F1_gsu"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11693">
        <property type="entry name" value="PTHR11693"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00231">
        <property type="entry name" value="ATP-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00126">
        <property type="entry name" value="ATPASEGAMMA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52943">
        <property type="entry name" value="SSF52943"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03323">
        <property type="entry name" value="alt_F1F0_F1_gam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="7" id="KW-0139">CF(1)</keyword>
    <keyword evidence="4" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC91923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="307" mass="33957" checksum="E224424E21B7E396" modified="2018-07-18" version="1">MSDTLASLRGKISGADKLKSVVRTMKAMAASSIGQYENAVQSLGDYERTVTLGLSACFRQAGPVVTPHFQQNEHKVIGAIVFGSDQGLVGQFNDVMGRFVMDKLDKLPGEKKIWVVGERLHAILGDANLPLFGPYGVPNSATAITQLVGRIQIDCEAHRPHSEFDYDQETIYVFHNAPLSGSQYQPVCQRLLPLDAEWQRNITAIPWPTKNLPEAIGMKTGRESETGNELLRALLREYLFISLFKACAESLVSENASRLAAMQRAEKNINELSTVLSRTFYRLRQNSIDEELFDVVAGSNALGNKVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GW58</accession>
    <name>A0A2S9GW58_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Serine O-acetyltransferase</fullName>
            <ecNumber evidence="3">2.3.1.30</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_3452</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>acetyl-CoA + L-serine = CoA + O-acetyl-L-serine</text>
            <dbReference type="Rhea" id="RHEA:24560"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:58340"/>
            <dbReference type="EC" id="2.3.1.30"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the transferase hexapeptide repeat family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.30" evidence="3"/>
    <dbReference type="EMBL" id="PUGF01000018">
        <property type="protein sequence ID" value="PRC91896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91896">
        <property type="protein sequence ID" value="PRC91896"/>
        <property type="gene ID" value="S2091_3452"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009001">
        <property type="term" value="F:serine O-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006535">
        <property type="term" value="P:cysteine biosynthetic process from serine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03354">
        <property type="entry name" value="LbH_SAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045304">
        <property type="entry name" value="LbH_SAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042122">
        <property type="entry name" value="Ser_AcTrfase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005881">
        <property type="entry name" value="Ser_O-AcTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01172">
        <property type="entry name" value="cysE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC91896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="245" mass="26489" checksum="0782B64C9DFDACAB" modified="2018-07-18" version="1">MFSRLREDIQNIMRRDPAARSAWEVLTCYPGLHAIVMHRWAHFFWRHQWYWLGRFTSHIARLLTGIEIHPGATIGRRVFIDHGFGVVIGETAVIGDECTIYQGVTLGGTSLSKGAKRHPTLERGVIIGAGAQVLGGFTIGAEAKVGSNSVVVKAVPAGATAVGNPAHIITKQAGEDAVARFAAYGVTAGGDDPVSKALHKLIDHAALQEQQILSLQLALKQAGIVCEEKASQEQFDPEQLNKLVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWA3</accession>
    <name>A0A2S9GWA3_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Oxygen-dependent choline dehydrogenase</fullName>
            <shortName evidence="5">CDH</shortName>
            <shortName evidence="5">CHD</shortName>
            <ecNumber evidence="5">1.1.99.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Betaine aldehyde dehydrogenase</fullName>
            <shortName evidence="5">BADH</shortName>
            <ecNumber evidence="5">1.2.1.8</ecNumber>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">betA</name>
        <name evidence="10" type="ORF">S2091_3336</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 7">
            <text>A + choline = AH2 + betaine aldehyde</text>
            <dbReference type="Rhea" id="RHEA:17433"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15354"/>
            <dbReference type="ChEBI" id="CHEBI:15710"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="EC" id="1.1.99.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>betaine aldehyde + H2O + NAD(+) = glycine betaine + 2 H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:15305"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15710"/>
            <dbReference type="ChEBI" id="CHEBI:17750"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.2.1.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="5 7">Amine and polyamine biosynthesis; betaine biosynthesis via choline pathway; betaine aldehyde from choline (cytochrome c reductase route): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.99.1" evidence="5"/>
    <dbReference type="EC" id="1.2.1.8" evidence="5"/>
    <dbReference type="EMBL" id="PUGF01000017">
        <property type="protein sequence ID" value="PRC91994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91994">
        <property type="protein sequence ID" value="PRC91994"/>
        <property type="gene ID" value="S2091_3336"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00529">
        <property type="reaction ID" value="UER00385"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008802">
        <property type="term" value="F:betaine-aldehyde dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008812">
        <property type="term" value="F:choline dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019285">
        <property type="term" value="P:glycine betaine biosynthetic process from choline"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00750">
        <property type="entry name" value="Choline_dehydrogen"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011533">
        <property type="entry name" value="BetA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="PTHR11552"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000137">
        <property type="entry name" value="Alcohol_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01810">
        <property type="entry name" value="betA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00623">
        <property type="entry name" value="GMC_OXRED_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00624">
        <property type="entry name" value="GMC_OXRED_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5 6" id="KW-0274">FAD</keyword>
    <keyword evidence="2 5 6" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0520">NAD</keyword>
    <keyword evidence="4 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GMC_OxRdtase_N" evidence="8">
        <location>
            <begin position="86"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="domain" description="GMC_OxRdtase_N" evidence="9">
        <location>
            <begin position="261"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="475"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="8"/>
            <end position="37"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS00623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS00624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC91994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="557" mass="61318" checksum="8924C49DA2EC798D" modified="2018-07-18" version="1">MNKQAEFDYIIIGAGSAGNVLATRLTEDADVTVLLLEAGGPDYRLDWRTQMPAALAFPLQGKRYNWAYETDPEPHMNNRRMQCGRGKGLGGSSLINGMCYIRGNALDYDNWASAEGMESWSYLDCLPYFRKAETRDIGANSYHGDNGPVSVATPKHGNNVLYNAMIEAGAQAGYPRTDDLNGFQQEGFGPMDRTTTPNGRRASTARGYLDQARQRANLTIVTHALTDRILFTGKRATGVAYLHRDTLQTALARREVLLCSGAIASPQILQRSGVGPADLLRKLDVPVVHDLPGVGANLQDHLEIYQQYECKLPVSLSPALKLYNQPKIGAEWLFLGTGIGATNQFEAGGFIRSNENFAWPNIQYHFLPVAINYNGSNPIKVHSFQAHMGSMRSPSRGRIALRSKDPREHPSILFNYMSHEQDWTEFRAGIRITREIMQQQALAPYTGKEISPGAEVSSDAELDAFVREHGETAFHPSCTCKMGYDAMAVVDNQGRVHGMESLRVIDASIMPEIVTGNLNAPTIMIAEKLADVIRGRVPLAKVETPYYIANGAPARLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWE4</accession>
    <name>A0A2S9GWE4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NADH:flavin oxidoreductase / NADH oxidase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_3318</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000017">
        <property type="protein sequence ID" value="PRC91976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91976">
        <property type="protein sequence ID" value="PRC91976"/>
        <property type="gene ID" value="S2091_3318"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001155">
        <property type="entry name" value="OxRdtase_FMN_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00724">
        <property type="entry name" value="Oxidored_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Oxidored_FMN" evidence="2">
        <location>
            <begin position="6"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="domain" description="Pyr_redox_2" evidence="3">
        <location>
            <begin position="390"/>
            <end position="587"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC91976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="686" mass="75712" checksum="298E7CF4878B96A0" modified="2018-07-18" version="1">MRYPNLFAPITINKVTIRNRIISTAHAEVYAENGVPGERYIRYYEEKAKGGVGLAICGGSSPVSIDSPQGWWKSVDLSNDRVIEPLARLAATMHKHGAKIMIQATHMGRRSSYHGEHWPHLLTPSGVREPVHRGNAKIIELHEIRRIVQDFASAAKRVQLAGMDGIEISAAHQHLIDQFWSPRTNKRTDEYGGSLQNRLRFGIEVLTAIREAVGRDFCVGLRMCGDEFHEDGLSHEMLKEIAVEMEKTGLIDYLSVIGSGADTHNTLVNCMPPMALPPEPFVHLAAGIKSVITLPLMHAQSIRDPVQAERVLANGMCDLVGMTRGQMADPHLVIKIRDGKEDQIKQCVGANYCIDRQYNGLDVLCIQNAATSREETMPHVIEKSPGKKRKVVVVGAGPAGLEAARVARERGHDVVLFEKNDQVGGQIILAAKAPQREQMAGIVRWFDMETKRLGIDRRLGVAATAEMILAEQPDIVVLATGGLNHTEENPNWKVPEGLAVSSWDILSGKVAPGKNVLVYDGISTHAGAGVADFIASRGNVVEMVTPDVKIADDVGGTTFPIFYRRMYALGVVMTPNYWLDGVAREGDKIIATLRNEYTDELEEREVDQVVIENGITPNDALYWELKERSVNLGHTDITTLFAAQPQPGLDQELAADQFMLFRVGDCISMHNIHAAIYDSLRLCKDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWE8</accession>
    <name>A0A2S9GWE8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative translation initiation inhibitor yjgF family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3192</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000016">
        <property type="protein sequence ID" value="PRC92057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92057">
        <property type="protein sequence ID" value="PRC92057"/>
        <property type="gene ID" value="S2091_3192"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02199">
        <property type="entry name" value="YjgF_YER057c_UK114_like_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013813">
        <property type="entry name" value="Endoribo_LPSP/chorism_mut-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035959">
        <property type="entry name" value="RutC-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14588">
        <property type="entry name" value="YjgF_endoribonc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55298">
        <property type="entry name" value="SSF55298"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YjgF_endoribonc" evidence="1">
        <location>
            <begin position="7"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="152" mass="16233" checksum="F005D71C8B19B570" modified="2018-07-18" version="1">MSFYEKLAELNIELPTVAAPVAAYVMYAQTGNTVFLSGHIAKKDGKPWVGQLGKNITTEEGKLAARSVAIDLMATLQAACGGDLNRVKRIVKLMSLVNSTPDFTEQHLVTNGASELIAEVFGEQGKHARSAFGVAQIPMGSCVEIELIVELA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWF8</accession>
    <name>A0A2S9GWF8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3194</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000016">
        <property type="protein sequence ID" value="PRC92059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92059">
        <property type="protein sequence ID" value="PRC92059"/>
        <property type="gene ID" value="S2091_3194"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021295">
        <property type="entry name" value="DUF2867"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11066">
        <property type="entry name" value="DUF2867"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="172" mass="19167" checksum="ED81A920C9F2E96B" modified="2018-07-18" version="1">MVKMVAVPVNSQISQHLENAHFYDAFQLNLAPCKRTALEIYLEVIAKTPSWISFLMALRNRAAPMFGLKDLGPLGNVQSCKPSTSYRVGDRVGIFTIHSMTDDEVILTDSDKHLEAKISVCKSLHGTANAVTVSTVVHVHNLLGHVYLFFVVPFHKRIVPSMLLQSESRTLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWH3</accession>
    <name>A0A2S9GWH3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cytochrome B561</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_3183</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000016">
        <property type="protein sequence ID" value="PRC92048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92048">
        <property type="protein sequence ID" value="PRC92048"/>
        <property type="gene ID" value="S2091_3183"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022904">
        <property type="term" value="P:respiratory electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011577">
        <property type="entry name" value="Cyt_b561_bac/Ni-Hgenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016174">
        <property type="entry name" value="Di-haem_cyt_TM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01292">
        <property type="entry name" value="Ni_hydr_CYTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81342">
        <property type="entry name" value="SSF81342"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="51"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="95"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="135"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="domain" description="Ni_hydr_CYTB" evidence="3">
        <location>
            <begin position="8"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC92048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="183" mass="20265" checksum="0EBF2E66AA35D50C" modified="2018-07-18" version="1">MSRAIASRYQPVLVALHWLIALMIIGLMCVGFFVLEEMPNIDPKKLDILKLHMAGGMFVFVLMILRVIIRTTSARPAPAESGSPRLNRLASITHLSLYVIVFLMIATGFSTGYVIRGAFQPNGALPDTFSVLPTFQAHAILATLLALLITGHVVAALYHHFVLKNGLFQRMWIGKRTIVPDEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWR8</accession>
    <name>A0A2S9GWR8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposase IS200 like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3080</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92164">
        <property type="protein sequence ID" value="PRC92164"/>
        <property type="gene ID" value="S2091_3080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002686">
        <property type="entry name" value="Transposase_17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036515">
        <property type="entry name" value="Transposase_17_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01797">
        <property type="entry name" value="Y1_Tnp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01321">
        <property type="entry name" value="Y1_Tnp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143422">
        <property type="entry name" value="SSF143422"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Y1_Tnp" evidence="1">
        <location>
            <begin position="9"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="243" mass="28361" checksum="F4907CC16DCE49AD" modified="2018-07-18" version="1">MARPLRLEFAGALYHVTSRGDRREDIFWDDADREEWLAVLAMACNRFNWVVHSYCHMTNHYHLLIETVEGNLSAGMRQLNGVYTQKFNRHHQQVGHLFQGRNKAILVQKEAHLLELSRYVVLNPVRACMVETPEEWPWSSYVACVSDEFAPPWLDTDWLLTQFGTQRKRACRAFQRFVLQGKGLASPLLATRHQLLLGDDDFIAQHQTDIKQENLREMSTAHRRTLALTLNEYQKNTQVEMNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GX23</accession>
    <name>A0A2S9GX23_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Thioredoxin peroxidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_2928</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92269">
        <property type="protein sequence ID" value="PRC92269"/>
        <property type="gene ID" value="S2091_2928"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000866">
        <property type="entry name" value="AhpC/TSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024706">
        <property type="entry name" value="Peroxiredoxin_AhpC-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
        <property type="entry name" value="AhpC-TSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000239">
        <property type="entry name" value="AHPC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="1" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="5">
        <location>
            <begin position="3"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="active site" description="Cysteine sulfenic acid (-SOH) intermediate" evidence="4">
        <location>
            <position position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00032824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000239-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC92269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="155" mass="17484" checksum="D332A299969E0992" modified="2018-07-18" version="1">MTVSPNNNLTDFSAAMTSEKTFTLSDYAGKNIVLYFYPKDNTPGCTTESIAFRDLYPQFQAANTEIFGLSRDSLRSHEGFKSKLDLPFELISDPDEIICTLFDVMKMKNMYGKQARGIERSTFLIDGNSKLVKEWRAVKVNGHVDDVLEFVSASK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GX72</accession>
    <name>A0A2S9GX72_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2967</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 5'(3')-deoxyribonucleotidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92308">
        <property type="protein sequence ID" value="PRC92308"/>
        <property type="gene ID" value="S2091_2967"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008253">
        <property type="term" value="F:5'-nucleotidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009264">
        <property type="term" value="P:deoxyribonucleotide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010708">
        <property type="entry name" value="5'(3')-deoxyribonucleotidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06941">
        <property type="entry name" value="NT5C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="214" mass="24008" checksum="F73D3BE5BBEC6EA6" modified="2018-07-18" version="1">MKKYNNSFKQRSGSIIALDADGVLLDYNAAYRLAWERAFGLLPDLRDKNAYWAIDRWDVSRLDGMELIKFRACFDEQYWKSIPAIPNAVKACEELCSAGYELVCVSAIESQFQHARLQNLQECGFPIERVIATSGSNTGISPKAAALRELNPIAFVDDFLPYLRGIPDDIHAALIMREPNGSPNLGGELNLAHSLHPDLQAFASWWLSESRCVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXG9</accession>
    <name>A0A2S9GXG9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2792</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92417">
        <property type="protein sequence ID" value="PRC92417"/>
        <property type="gene ID" value="S2091_2792"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015436633" evidence="2">
        <location>
            <begin position="20"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="130"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="133"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="161" mass="19127" checksum="539696125648B832" modified="2018-07-18" version="1">MKRLLLAALLAASPLLSMAQVNVDVNIGAPNFYGQVDLENDAPPPVVFLTPVVVQQVPSDVYYPPVYLRVPETYYQHWPQYCAMYNACYQPVFFVQESWYLQVYAPMYRSRYPYGRPGFTPRAYYGAPRYDYGPPRYDDRRDHRNERHDDRRDERRDDDRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXI5</accession>
    <name>A0A2S9GXI5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Peptidase C39 like family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2812</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92437">
        <property type="protein sequence ID" value="PRC92437"/>
        <property type="gene ID" value="S2091_2812"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021770">
        <property type="entry name" value="DUF3335"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11814">
        <property type="entry name" value="DUF3335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="195" mass="22000" checksum="64BEB2CCAB3886CA" modified="2018-07-18" version="1">MKAFKPNLDLNRTLELQLWREATTIFMTAGHGGCGPHGLALAALQRGFPCEIFVNGTGVLFQDSVRSPEKREVIQLVHEDFVEQVLRHKIPLHYKLAGSAELMRSFSAGGIPLVLISTYRLTRERAPHWVIITGCDDLYFYIHDPDNSDAREGDDRINIAVLKKDFERMARYGRQGSKAVVIVYPPQNPTPLTKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXI6</accession>
    <name>A0A2S9GXI6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2798</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92423">
        <property type="protein sequence ID" value="PRC92423"/>
        <property type="gene ID" value="S2091_2798"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="24"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="81"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="267"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="299"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="329"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="430" mass="48150" checksum="7A487BB8CC2ACBAE" modified="2018-07-18" version="1">MPNSRRFEYRLTTSQLHEPQNKHVLRLVYGLIIVAFAALFYLIFQKIGIENLDAYQVVKKTADNVLHNPAVLFKFATYSPYIHLIFYLFILVTVNWWVYILPTSYSLTLTDDELISNHQLPFGLNALIPAISPFNWHISLHDITAVELIQIPLFGKAMQRLTTPTFAFVRLRISQRSGPVRTINPAMWVVPGSLGRTPLKPVGKRDLLADFFSNVANRWLKPENQAILRAGLLDLPIAHALSERGVTMSEAAPHNIKEHDLFACRSIKFGIITALTLSSAALGILLLCKYQHLKFDFPLSLHLLICTTILCAFFLLNQNDKSRPPLLHTVLTALCLVGSMAIGAQPIAMFLNGFGVTSNQSQDFVIRAGKLEPIANFSGIGSIKLPGKESRQGWLQSGTKVTLKVTQGHFGLWEYNDEPLRQLVDAQGIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXQ8</accession>
    <name>A0A2S9GXQ8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_2865</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DoxX family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92490">
        <property type="protein sequence ID" value="PRC92490"/>
        <property type="gene ID" value="S2091_2865"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032808">
        <property type="entry name" value="DoxX"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07681">
        <property type="entry name" value="DoxX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="38"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="67"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="110"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC92490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="141" mass="15548" checksum="8D0D79B92ADCA645" modified="2018-07-18" version="1">MLTIDRNKNALIFLRILISCLIAVHGWHRLIYSDPADLGGAITDFGFPVGLALGWLITLVEAFGAPLFAMGWLVFPLGVFYTFVYVMAIIFYHAPHGWFSSGSGADGCEYAVLLVGGLLCVSTQHVPTWITVRGLKFWQRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXR0</accession>
    <name>A0A2S9GXR0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Aerobic-type carbon monoxide dehydrogenase large subunit CoxL/CutL-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2821</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92446">
        <property type="protein sequence ID" value="PRC92446"/>
        <property type="gene ID" value="S2091_2821"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000674">
        <property type="entry name" value="Ald_Oxase/Xan_DH_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036856">
        <property type="entry name" value="Ald_Oxase/Xan_DH_a/b_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016208">
        <property type="entry name" value="Ald_Oxase/xanthine_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008274">
        <property type="entry name" value="AldOxase/xan_DH_Mopterin-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037165">
        <property type="entry name" value="AldOxase/xan_DH_Mopterin-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11908">
        <property type="entry name" value="PTHR11908"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01315">
        <property type="entry name" value="Ald_Xan_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02738">
        <property type="entry name" value="Ald_Xan_dh_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01008">
        <property type="entry name" value="Ald_Xan_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54665">
        <property type="entry name" value="SSF54665"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56003">
        <property type="entry name" value="SSF56003"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ald_Xan_dh_C" evidence="2">
        <location>
            <begin position="18"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="570"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="570"/>
            <end position="592"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="749" mass="79822" checksum="A5A795555A9A87BA" modified="2018-07-18" version="1">MKNIGDPIARVDGRLKVTGAALYSAEIPLLKTAYAVLVTSTIASGRITVLDEDRARSIAGVIAVFSYKNAPRLSRPKMMPAGQSIPILQSPDIYYGGQVIAVVLAESLESATHAASLVTVSYSTKVAAIDMNAHLASAFVPAKRQTGEDPSSKRGDTTAGLAQADIKLDLLYTTPVEHHNPMEPHATTAVWEGDQLTVYDATQAVTNSAHSLAQILGVPVANVRVISRFLGGGFGCKGMSWPHVAIAAMTAREIKRPVKLVLTRPQMFTSNGHRPTTRQSIHIGANRDGKLMAINHHVDNHTSALDNFTEASGSPTEFLYACNNVEILHRLVRLNTGTPTFTRAPGFASGSFGLESAMDEMACKLDIDPVEFRLRNFAAHDQADNLPWSSNSLRECYAAAAARFGWEKRKATTGSQRDGRWLIGYGMASATYPAHFQAASANATIFADGKVLVQCGTQDLGTGTYTVMSQTAASVLGVEVEQVRFELGDTRLPPAPGSGGSTTAASAGSAVFNTVQKLRDRLIQLAATDTSSPLHGIDEKLIVIRDGRLSSTGVPGRSETLIKLLSRQSQPSVSVTSSTGPGPEQGYPTAQTPGNVPGEKPKSHHSYKIFGAHFCEVRVDPELGEVKVTRMVSAFAGGRILNARTARSQLQGGMIWGIGMALMEETRIDTQRGFFSNANLADYLLPVNADIPSIEALLVEEVDPYVNPIGSKGLGEIGIVGVAAAVANAVYNATGKRIRDLPITVDKII</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXV2</accession>
    <name>A0A2S9GXV2_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 11">Cysteine synthase</fullName>
            <ecNumber evidence="5 11">2.5.1.47</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">S2091_2593</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>hydrogen sulfide + O-acetyl-L-serine = acetate + L-cysteine</text>
            <dbReference type="Rhea" id="RHEA:14829"/>
            <dbReference type="ChEBI" id="CHEBI:29919"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:58340"/>
            <dbReference type="EC" id="2.5.1.47"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 9 11">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid biosynthesis; L-cysteine biosynthesis; L-cysteine from L-serine: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 11">Belongs to the cysteine synthase/cystathionine beta-synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.47" evidence="5 11"/>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92538">
        <property type="protein sequence ID" value="PRC92538"/>
        <property type="gene ID" value="S2091_2593"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00136">
        <property type="reaction ID" value="UER00200"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004124">
        <property type="term" value="F:cysteine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006535">
        <property type="term" value="P:cysteine biosynthetic process from serine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005856">
        <property type="entry name" value="Cys_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005858">
        <property type="entry name" value="CysM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001216">
        <property type="entry name" value="P-phosphate_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="PLP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="Trypto_synt_PLP_dependent"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10314:SF100">
        <property type="entry name" value="PTHR10314:SF100"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="SSF53686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01136">
        <property type="entry name" value="cysKM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01138">
        <property type="entry name" value="cysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00901">
        <property type="entry name" value="CYS_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="8 11" id="KW-0198">Cysteine biosynthesis</keyword>
    <keyword evidence="7 9 11" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PALP" evidence="12">
        <location>
            <begin position="7"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Pyridoxal phosphate binding" evidence="9">
        <location>
            <begin position="180"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="77"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="261"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="10">
        <location>
            <position position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR605856-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR605856-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PRC92538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="300" mass="32181" checksum="1F9896761647A2BE" modified="2018-07-18" version="1">MSYMTIEDTIGNTPLVQLKRIPSNLATQRNNIILAKLEGNNPAGSVKDRPALSMILAAEKRGQIKPGDTLIEATSGNTGIALALVAAMRGYKMTLLMPENLSVERRQSMAAYGAQIILTPKTGGMEYARDLAEKMQAEGQGVILDQFANPDNPLAHYTGTGPEIWRDTNGAVTHFVSAMGTTGTIMGVSSYLKEQNSQIQIIGAQPEEGSQIPGIRKWPEAYLPKIFDAARVDQVISVSQANAEHMARKLAIEEGIFAGVSSGGACDVALRLAETVENATIVFIVCDRGDRYLSTGIFPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXW3</accession>
    <name>A0A2S9GXW3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Reactive intermediate/imine deaminase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2619</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RutC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92564">
        <property type="protein sequence ID" value="PRC92564"/>
        <property type="gene ID" value="S2091_2619"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006056">
        <property type="entry name" value="RidA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035959">
        <property type="entry name" value="RutC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006175">
        <property type="entry name" value="YjgF/YER057c/UK114"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11803">
        <property type="entry name" value="PTHR11803"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01042">
        <property type="entry name" value="Ribonuc_L-PSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55298">
        <property type="entry name" value="SSF55298"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00004">
        <property type="entry name" value="TIGR00004"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="130" mass="14488" checksum="3A98302A1A0E24E0" modified="2018-07-18" version="1">MSKEIIRFGNVPSGAGGQRLPFSPAVRAGDFVFCSGQVAMKENGEVEDGGIEAQTRRTFANVEKVLALADCSLQDVVKVTVWLDDTRDFWTFNRIYMEYFGEHPPARSCVQSAMMVDCKIEIEVTAYKPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GY50</accession>
    <name>A0A2S9GY50_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="11">TonB family C-terminal domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">S2091_2641</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
            <orientation evidence="1">Periplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TonB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92586">
        <property type="protein sequence ID" value="PRC92586"/>
        <property type="gene ID" value="S2091_2641"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006260">
        <property type="entry name" value="TonB/TolA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037682">
        <property type="entry name" value="TonB_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03544">
        <property type="entry name" value="TonB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01352">
        <property type="entry name" value="tonB_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_C" evidence="10">
        <location>
            <begin position="136"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF03544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC92586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="215" mass="23069" checksum="FC4D0A84BEF3493A" modified="2018-07-18" version="1">MNFTLDIQKQGTSMTGFILVVALHLALLSALIFGLKLANMPPTHVDDVIYVSPKTEPPKPIEPLEKVKLRDPVMPVITPPNYPVPTDTFIPVTTTPEQPTGSKGGIDSGSTEHSVADVKPAALFVGAVVDAKSCDKPEYPRNALRNEYTGVVTLALLIGLDGKVIDAKVEQTSGHKELDQAALAGLSLCKFKPATLNGQAQKSWAKLQYAWNVAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYC9</accession>
    <name>A0A2S9GYC9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2453</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92723">
        <property type="protein sequence ID" value="PRC92723"/>
        <property type="gene ID" value="S2091_2453"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="62" mass="7051" checksum="F1C3F57C81B1EC88" modified="2018-07-18" version="1">MDQVTTGIAAIVIFLVITIGIFVICRELVCWYWKINKSIELQQEIAQSLKEIAATLKAQRQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYF3</accession>
    <name>A0A2S9GYF3_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SURF1-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_2487</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the SURF1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92757">
        <property type="protein sequence ID" value="PRC92757"/>
        <property type="gene ID" value="S2091_2487"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd06662">
        <property type="entry name" value="SURF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002994">
        <property type="entry name" value="Surf1/Shy1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045214">
        <property type="entry name" value="Surf1/Surf4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23427">
        <property type="entry name" value="PTHR23427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02104">
        <property type="entry name" value="SURF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50895">
        <property type="entry name" value="SURF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="34"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="243"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC92757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="271" mass="29499" checksum="D29B73D2B6D2EEE2" modified="2018-07-18" version="1">MTLQKNGTPGAATLPEPGVTGQDDITRSRSMLRIVSVTVCATLIFACFTSLGIWQIQRLFWKRALIERVEQRVHAPAVAAPTPDNWSEIKATKDEYRHVSLSGIFLHKFTTPVKAVTGLGDGFWLLTPLLCADGSVVIINRGFIPTKEFNSTATNSLPNSDPLLVSGLLRMNEPGGAFLRHNNPAENRWFSRDVVAIAAVHHLSPVAPYFVDEGALAGHAQQSSPAAYPIGGLTMISFSNNHLVYTLTWFALACMVAGAGFWVVCGELRLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYS1</accession>
    <name>A0A2S9GYS1_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9 10">Translation initiation factor IF-2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">infB</name>
        <name evidence="14" type="ORF">S2091_2294</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9 10">One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9 10">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92877">
        <property type="protein sequence ID" value="PRC92877"/>
        <property type="gene ID" value="S2091_2294"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03702">
        <property type="entry name" value="IF2_mtIF2_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10050">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00100_B">
        <property type="entry name" value="IF_2_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013575">
        <property type="entry name" value="IF2_assoc_dom_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044145">
        <property type="entry name" value="IF2_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006847">
        <property type="entry name" value="IF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000178">
        <property type="entry name" value="TF_IF2_bacterial-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015760">
        <property type="entry name" value="TIF_IF2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023115">
        <property type="entry name" value="TIF_IF2_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036925">
        <property type="entry name" value="TIF_IF2_dom3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43381">
        <property type="entry name" value="PTHR43381"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11987">
        <property type="entry name" value="IF-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08364">
        <property type="entry name" value="IF2_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04760">
        <property type="entry name" value="IF2_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52156">
        <property type="entry name" value="SSF52156"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00487">
        <property type="entry name" value="IF-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01176">
        <property type="entry name" value="IF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 9" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5 9 10" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="6 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 9 10" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="13">
        <location>
            <begin position="504"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="326"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="362"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="region of interest" description="G-domain" evidence="9">
        <location>
            <begin position="507"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="133"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="332"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="395"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="513"/>
            <end position="520"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="559"/>
            <end position="563"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="613"/>
            <end position="616"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="PRC92877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="1004" mass="108042" checksum="218D50C2A3051B4B" modified="2018-07-18" version="1">MASNNVSQFATELKMSADVLLTQLRSAGVVKGSTSDDLSKEDKERLLEHLRRTHGVEADGDTKKITLTRKETTEIKQADATGKSRTIQVEVRKKRTFVKRDETLPESDKPVVSPTAEELAKQAEEDRLADELRAKQEAELIEKQNHLARLEAEKEAQNKALQEAELAAAKEAELVAISAAKRAAAQEDAAKLQASQTKRKAPPAKVAEVAAETTAAADPVVPVEAAVVDKVDDKNDAKNDAKKIVAAEVAKRLADEVEATEQKKAADSVIAAQAATKVATERAAATENARKAVADEVAQIKAMMSTQRKPVKAPVPVVAEVPKVATKAPEGTLHKPADKKPTEKKDEKKVVVVDKKSIKSANVSSTWQDDAAKKKGLKTRGNTAPGPGGRDGWRAGGKNSRRGSHSDDRETNFQAPVEAVVKDVYVPETITVAELAHKMSVKASEVIKQLMKLGQMVTINQVLDQETALILVEEMGHKAFAAKLDDPEAMLVDGGVQIEYQSFPRAPVVTVMGHVDHGKTSLLDYIRRAKVASGEAGGITQHIGAYHVETPRGMITFLDTPGHEAFTAMRARGAKATDIVILVVAADDGVMPQTKEAIAHAKAAGVPLVVAVNKIDKPGANLDRVKQELIAENVLPEEYGGDSPFVSVSAKTGQGIDELLEQVLLQAEVLELRAAKDAPARGLVVEARLDKGRGPVATILVQSGTLKRGDVVLAGSSYGRVRAMLDENGVSITEAGPSIPVEIQGLTEVPNAGEEVMVMADERKAREIGQFRQGKYRDVKLAKQQAAKLENMFENMGEGEVKTLAMIIKTDVQGSQEALVHSMQKLSTSEVRVQVVHAAVGGISESDVNLAVASKAVLIGFNTRADASARKLAEANGIDIRYYNIIYDAVDDVKAALSGMLAPEKREHALGLVEIRQVITISKVGAIAGCYVLEGLVKRGSSIRLLRNNVVVWTGELDSLKRFKDDVKEVKFGFECGLSLKNFNDIQVGDQLEVFEVQEVARTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZ02</accession>
    <name>A0A2S9GZ02_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Endonuclease III</fullName>
            <ecNumber evidence="10">4.2.99.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">DNA-(apurinic or apyrimidinic site) lyase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">nth</name>
        <name evidence="12" type="ORF">S2091_2354</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'-deoxyribonucleotide-DNA = a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + a 5'-end 5'-monophospho-2'-deoxyribonucleoside-DNA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:66592"/>
            <dbReference type="Rhea" id="RHEA-COMP:13180"/>
            <dbReference type="Rhea" id="RHEA-COMP:16897"/>
            <dbReference type="Rhea" id="RHEA-COMP:17067"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:136412"/>
            <dbReference type="ChEBI" id="CHEBI:157695"/>
            <dbReference type="ChEBI" id="CHEBI:167181"/>
            <dbReference type="EC" id="4.2.99.18"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="10">Binds 1 [4Fe-4S] cluster.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the Nth/MutY family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.99.18" evidence="10"/>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92937">
        <property type="protein sequence ID" value="PRC92937"/>
        <property type="gene ID" value="S2091_2354"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140078">
        <property type="term" value="F:class I DNA-(apurinic or apyrimidinic site) endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019104">
        <property type="term" value="F:DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00056">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1670.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00942">
        <property type="entry name" value="Nth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011257">
        <property type="entry name" value="DNA_glycosylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004036">
        <property type="entry name" value="Endonuclease-III-like_CS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003651">
        <property type="entry name" value="Endonuclease3_FeS-loop_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003265">
        <property type="entry name" value="HhH-GPD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023170">
        <property type="entry name" value="HhH_base_excis_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000445">
        <property type="entry name" value="HhH_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005759">
        <property type="entry name" value="Nth"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00633">
        <property type="entry name" value="HHH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00730">
        <property type="entry name" value="HhH-GPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00478">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00525">
        <property type="entry name" value="FES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48150">
        <property type="entry name" value="SSF48150"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01083">
        <property type="entry name" value="nth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01155">
        <property type="entry name" value="ENDONUCLEASE_III_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 10" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="4 10" id="KW-0227">DNA damage</keyword>
    <keyword evidence="8 10" id="KW-0234">DNA repair</keyword>
    <keyword evidence="10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="12" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="9 10" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 10" id="KW-0408">Iron</keyword>
    <keyword evidence="7 10" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="10" id="KW-0456">Lyase</keyword>
    <keyword evidence="3 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0540">Nuclease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ENDO3c" evidence="11">
        <location>
            <begin position="38"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="187"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="194"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="197"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="203"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PRC92937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="216" mass="23968" checksum="B0B16B9F94B9963F" modified="2018-07-18" version="1">MNASQRISFFQRLQTTNPHPSTELEYTTPFELLIAVLLSAQATDVSVNLATRRLYLVANTPAKILALGEAELIPFIASIGLYKTKAKHIIATCQILLNQHNGQVPRERSALEALPGVGRKTANVVLNSAFGEPTIAVDTHIFRVGNRTGLAVGETVEKVEQQLLKNVPEEFKLNAHHWLILHGRYTCKARQPLCWNCMLTDLCDYQQKTPMPGKGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZ13</accession>
    <name>A0A2S9GZ13_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Type IV pilus biogenesis and competence protein PilQ</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">S2091_2283</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Required for type IV pilus biogenesis and competence. Could function as a pore for exit of the pilus but also as a channel for entry of heme and antimicrobial agents and uptake of transforming DNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Homododecamer. Tetramer of trimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial secretin family. GSP D subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92866">
        <property type="protein sequence ID" value="PRC92866"/>
        <property type="gene ID" value="S2091_2283"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015627">
        <property type="term" value="C:type II protein secretion system complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030420">
        <property type="term" value="P:establishment of competence for transformation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015628">
        <property type="term" value="P:protein secretion by the type II secretion system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.120">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001775">
        <property type="entry name" value="GspD/PilQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005644">
        <property type="entry name" value="NolW-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038591">
        <property type="entry name" value="NolW-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004846">
        <property type="entry name" value="T2SS/T3SS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013356">
        <property type="entry name" value="T2SS_GspD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004845">
        <property type="entry name" value="T2SS_GspD_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00263">
        <property type="entry name" value="Secretin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03958">
        <property type="entry name" value="Secretin_N"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00811">
        <property type="entry name" value="BCTERIALGSPD"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02517">
        <property type="entry name" value="type_II_gspD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00875">
        <property type="entry name" value="T2SP_D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0178">Competence</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1134">Transmembrane beta strand</keyword>
    <keyword evidence="11" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Secretin_N" evidence="13">
        <location>
            <begin position="154"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="domain" description="Secretin_N" evidence="13">
        <location>
            <begin position="217"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="domain" description="Secretin_N" evidence="13">
        <location>
            <begin position="291"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="315"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="717"/>
            <end position="758"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="315"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="358"/>
            <end position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00014124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00025897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF03958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="PRC92866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="758" mass="79495" checksum="099F0F63A2E633CD" modified="2018-07-18" version="1">MKNMRMTPSILTPLKRNLTLAYTGNFSLRKLPASLAFCAITGLFSVAAFAQEPSLNESKLTFVGADIESVIKAVGHYTGTTFIVDPRVKGTINLVSEQPVTKEQAFALLTSTLRLQGYAVVTANGFTKVVPEPDGKLQAGPTQVVGIKGDQISTQIYRLNYENAANLVTVLRPLISPNNTINANPGSNSVVITDYADNLKRLEKIIATLDVPATSDVDVIPVKYGIASDIATLVLRLTEQSGASADSGKVNILADSRTNSILLHAPSVARANLVKTLIEKLDQPTALPGNVHVVYLRNADALKLAQTLRAIAASDSSSSGSGSLSNVNSGNNSAQQPSQNKPTTGIGGSGSGSGGGLGSALGASTSNNGNAPTTLSTGGATGYIQADSATNTLIITASETVYRNLRTVIDQLDARRSQVYIEALIIEVSTNKAEQFGVQWAALTGNSNSNVRVGSATSFNTGGASNNLFNLAAAGKTAVPNAGLNLGVFSAQLGLGALASALQSTGNANVLSVPTLTTLDNEEAKMLVGQNVPFITGQYTNTAASSGGATVNPFQTIERKDVGVTLRVKPQISEGGAVKLTIYQEVSNIDSSTNPAGIITNVRAIETNVIVDDGQVLVLGGLMAESGNETNDQVPILGDIPYIGNLFKYKNKSHIKSNLLIFLRPTVIRNPDQSHSVSVDRYDYMRAKVRTDKPDEPLLNVPSLTPEQTGILIPQNILNRESTATKLDTQDGAKSGTKPDTSPVTKPETTTTPTEAAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZ33</accession>
    <name>A0A2S9GZ33_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Chemotaxis signal transduction protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2387</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92970">
        <property type="protein sequence ID" value="PRC92970"/>
        <property type="gene ID" value="S2091_2387"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039315">
        <property type="entry name" value="CheW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036061">
        <property type="entry name" value="CheW-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002545">
        <property type="entry name" value="CheW-lke_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22617">
        <property type="entry name" value="PTHR22617"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01584">
        <property type="entry name" value="CheW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00260">
        <property type="entry name" value="CheW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50341">
        <property type="entry name" value="SSF50341"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50851">
        <property type="entry name" value="CHEW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CheW-like" evidence="1">
        <location>
            <begin position="24"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="172" mass="18990" checksum="F71121F2085B4A16" modified="2018-07-18" version="1">MLPSSQAENHSANHSTKLSHDVAGSEFLAFTLGKEEYGIDILKVQEIRGYEAVTRIANAPVFVKGVINLRGIIVPVVDMRIKFDLGTPTYDQFTVVIILNINSRIVGMVVDSVSDVTTLTTEQIKPPPEMDTTFNSDYLIGLGTIEERMLILVDIDKLMTSPDMGLVDHQIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZ51</accession>
    <name>A0A2S9GZ51_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">MCP-signal associated domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2323</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92906">
        <property type="protein sequence ID" value="PRC92906"/>
        <property type="gene ID" value="S2091_2323"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025991">
        <property type="entry name" value="Chemoreceptor_zinc-bind_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13682">
        <property type="entry name" value="CZB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CZB" evidence="1">
        <location>
            <begin position="42"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="151" mass="17268" checksum="A2CD259AE012D81A" modified="2018-07-18" version="1">MFKIFSFLKSGSRTDNVPDLANNQIQEKVARDLDVKSAVLAHENWKLRLTAYLSDQSTENLRPEVICFDDRCDLGKWLHGDAKQCFGDHPRFQSLVGEHKNFHYHASNVVSLKMQGKKEKAELLLNSEFQKCSERVISMLNELGDETVVAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZ60</accession>
    <name>A0A2S9GZ60_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Sugar (And other) transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_2333</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92916">
        <property type="protein sequence ID" value="PRC92916"/>
        <property type="gene ID" value="S2091_2333"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="34"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="58"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="94"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="127"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="169"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="193"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="243"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="278"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="308"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="333"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="373"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="401"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="22"/>
            <end position="428"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC92916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="428" mass="46557" checksum="5B66FBCC67081477" modified="2018-07-18" version="1">MTNINTKATSSPPDQHPQTWRAVISSSIGNALEWFDILIYGAFAVTIAKLFFPTADPTVSLMITFATFGVSFFMRPLGAIILGTYSDRVGRKAALTLSILLMMVGTFLIAVMPTYNSIGLWAPAGIVLARLIQGFSAGGEFGSSTAFLVEHAPHRRGFFSSWQVASQGLSMLLAALAGAVLSSQLTVEQLESWGWRLPFIFGLLIGPAGLYIRQHLEESPEFTEADATSTPLRDILAQQKERLLIGSGCVVMATVSVYTILYMPTYAVKQLKMTSTEAFSATMLAGVIMMLLSPFIGHFSDKYGRTPFMLASSVLFALLTYPLFHFLTLNPSFANLLMVQAMLGLLMTMYFAAMPALLSDIFPVQTRGTGMSLSYNIGVMIFGGFAGMVITWLIAATKNNLAISFYVIVGAVISIIATLAARYRLRLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZI2</accession>
    <name>A0A2S9GZI2_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ribosomal RNA large subunit methyltransferase E</fullName>
            <ecNumber evidence="4">2.1.1.166</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">23S rRNA Um2552 methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">rRNA (uridine-2'-O-)-methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rlmE</name>
        <name evidence="4" type="synonym">ftsJ</name>
        <name evidence="4" type="synonym">rrmJ</name>
        <name evidence="7" type="ORF">S2091_2231</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>S-adenosyl-L-methionine + uridine(2552) in 23S rRNA = 2'-O-methyluridine(2552) in 23S rRNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42720"/>
            <dbReference type="Rhea" id="RHEA-COMP:10202"/>
            <dbReference type="Rhea" id="RHEA-COMP:10203"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74478"/>
            <dbReference type="EC" id="2.1.1.166"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.166" evidence="4"/>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93145">
        <property type="protein sequence ID" value="PRC93145"/>
        <property type="gene ID" value="S2091_2231"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008650">
        <property type="term" value="F:rRNA (uridine-2'-O-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01547">
        <property type="entry name" value="RNA_methyltr_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002877">
        <property type="entry name" value="RNA_MeTrfase_FtsJ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015507">
        <property type="entry name" value="rRNA-MeTfrase_E"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01728">
        <property type="entry name" value="FtsJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005461">
        <property type="entry name" value="23S_rRNA_mtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="3 4 5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="FtsJ" evidence="6">
        <location>
            <begin position="28"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4 5">
        <location>
            <position position="167"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="60"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="62"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="86"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="102"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="127"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR005461-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC93145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="211" mass="23623" checksum="1C134D1D9C86A783" modified="2018-07-18" version="1">MAKNKFNQNWLHDHINDPYVKLAQREGYRARAVYKLKEIDEAEKLIKPGQIIVDLGATPGSWSQYVRNKLAGKAGGGILGEIFALDMLPMEPIADVQFLLGDFREQEILDLLETRLLGRKVDLVLSDMAPNLSGIPTADAARMEDIIELAIEFSKAHLKPTGSLLVKCFHGPAYNTVWDRFKSEFKVVSSKKPKASRDKSSEIFILGRGLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZU9</accession>
    <name>A0A2S9GZU9_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_1961</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93223">
        <property type="protein sequence ID" value="PRC93223"/>
        <property type="gene ID" value="S2091_1961"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="157"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="5">
        <location>
            <begin position="236"/>
            <end position="450"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC93223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="460" mass="51042" checksum="1C6B98928094C9BF" modified="2018-07-18" version="1">MDGFKTKLSSSLQFRIALALTIVMVIAAMSIGAIGFYSAFHDAHELQDDQLRDIAAMTDAERLTVGQANALAPSELEDPESHFIVQLIDPNSSVATSEPSTDIKFPNNLTNGTKTLLVQHKKWRVFVRPLPSGEKLVVGQRTEVRDEIAEHAGFRTLVPILVLIPFLIVLIIAVLRWMLAPLTKLSAELNARHPEDMRELHSHDLPTELRPFIVSINSMLSRLSLVLEQQRRFVADAAHELRSPLTALSLQTQNLATHALPDAVQGQLHEFRRGLKRANELVEQLLALARAQLDLPTKLQPVSLQLVVKTVFEEMMPLADSKKIEIGLEQNAEVYVEASEVDLVTVLRNLVDNAIRYTNIEGRVDVMIKIDNAWAVIEVQDNGPGISQEEQERVFDPFYRILGSKQTGSGLGLSIVKSIVTKLRGEVAMRCANLSSASGLVAQVKLPLLQRSDFATMDKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0B1</accession>
    <name>A0A2S9H0B1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1809</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93422">
        <property type="protein sequence ID" value="PRC93422"/>
        <property type="gene ID" value="S2091_1809"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015758993" evidence="1">
        <location>
            <begin position="30"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="326" mass="37038" checksum="2491CA70C6BA6492" modified="2018-07-18" version="1">MKAPPFFYSARVMASIAAMILVSLFYACAQAEPIDEDAASRHVYATGGVHNEKNCEPPHRCVFPRKPGEPVDPAFPAFWTSEWTMYRVFNNEDKFPPPYSSPPKGLSTSDYEVSYGASYYDSTYTPKDGDGHGAMMEHYEKRCLPIFPSSNKYSCSFVSLGNKAYFLRYADRPPGTPACCQFSLQNHPPERDFIKHLPYNAEQSSHLDGSIDAYSRLMSLQKILFGYAFEKLPRPDIVDKTAPPYRHPQSFFFAGYPLDPPDAPIVSQNYRNFRMEKPNPIYTWDQVPLMCPPVPVWCCLFTGDCPVKEKESEVQPVAAQWNNIQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0G7</accession>
    <name>A0A2S9H0G7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">HlyD family secretion protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1858</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93471">
        <property type="protein sequence ID" value="PRC93471"/>
        <property type="gene ID" value="S2091_1858"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="361" mass="39818" checksum="A9A7666E69475741" modified="2018-07-18" version="1">MRNKIIFALSIFGVLAGLVTAYILGVEKHAQPPVFKPVSSPYDAAIYANGMIESEQQAGVNINIYPEVSGPIIKVLAHEGQKVVADMPLFLIDDSVQKATTEQLRLQSAAALVLLQELKAQPRKETLAVAKAQVDQADANLNAVRDQYDKRRASFDLDHRSISKDVVDTAKDAVAQAVTGLALATNQYELIKAGAWSFDIANQEKQVEALRQSYQAADALLQKYVVKAQTDGVVMALNATVGSYVSSLGVYDSYTQGNDPLAVMGTPQNYLDVRCFIDEILVSRLPAPEHIRAEMSIRGTEIKVPLEFVRVQPYVSPKIELSNQRQEKVDLRVLPVIFRFPKKDLTMVYPGQQVDVYIGQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0J5</accession>
    <name>A0A2S9H0J5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1889</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93502">
        <property type="protein sequence ID" value="PRC93502"/>
        <property type="gene ID" value="S2091_1889"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015635834" evidence="1">
        <location>
            <begin position="30"/>
            <end position="440"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="440" mass="49729" checksum="DD5F103315B29123" modified="2018-07-18" version="1">MKNKNTSQPATQFAIFLLLTHLAFSPIFAAVTVPPILEKQLPEITRLKDLKEAENNLTKQENADINDSTEKFWHTDAALDHLATMQSFAGDSVGAVKNFDRLSKSRELNSKSQPRDTSDVLIDINAAKIEDAISAITREAKTRQVVILNEAHHVPVHRVFAMLLARELKKIGYEYLACETFDSSTPFPLANGYVVKDTGYYSSETMYASFLNDAVKSGWKFVSYDHWPDPKLSGEKNFKNRETGEAANLVDRVFKQNPKAKIFIYVGYGHASKFPKSVEENDKSMMAAQLIRMTGINPLTIDQTKMYQHFDNQFQFDVYNAVLKNLTIEKPSVLISPQNMYLRFGGKATLSDAYDMQVIHPIYAVDDVTKRPIWMGSLAALTPHDIPYALLPVIGRRLIYAYRLNDPLDAMPVDVVIVEAGKLIPKLMLPEGEFRYSYED</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0K3</accession>
    <name>A0A2S9H0K3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Dioxygenases related to 2-nitropropane dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1896</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93509">
        <property type="protein sequence ID" value="PRC93509"/>
        <property type="gene ID" value="S2091_1896"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018580">
        <property type="term" value="F:nitronate monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04730">
        <property type="entry name" value="NPD_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004136">
        <property type="entry name" value="NMO"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03060">
        <property type="entry name" value="NMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NMO" evidence="1">
        <location>
            <begin position="12"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="385" mass="41564" checksum="BE9FBF3D4398EC03" modified="2018-07-18" version="1">MLKTAFRLLKIKEKIVLPIVQGGMGIGVSAHRLAGSVARLGAVGTISSVDLRRHHPDLMAQTERSRDKALINAVNLTALDREIRAAKTLANGHGMIAVNVMRAVADYAAYVRQSCESGADAVVVGAGLPLDLPELTANYPDVALIPILSDARGISLVLKKWMRKNRLPDAIVIESPRYAAGHLGAARLEDVSDPRFAFKAVLESTFELLKELGLEREKIPLIVAGGITSHEQMGELMALGASAIQLGTPFAVTQEGDAHPNFKTVLAEARPEDIVTFMSVAGLPARAVRTPWLARYLEKEAKLQKKAGVKQCTVGFDCLQQCGLRDGIGKAGQFCIDTQLAFALNGDVKRGLFFRGSESLPFGNAIRPVRELLEYFLTGLRPIIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0L0</accession>
    <name>A0A2S9H0L0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acetyltransferase (GNAT) domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1911</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93524">
        <property type="protein sequence ID" value="PRC93524"/>
        <property type="gene ID" value="S2091_1911"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038740">
        <property type="entry name" value="BioF2-like_GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13480">
        <property type="entry name" value="Acetyltransf_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Acetyltransf_6" evidence="1">
        <location>
            <begin position="190"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="369" mass="42718" checksum="2BD327805517EFEE" modified="2018-07-18" version="1">MTQVCVYTNFDALPAAYRALFDASCQRDGFFLSWPWFHNLSRKGMEASLNLRIYGVESSELQSHIQSETPQLKAHLALPMCFSASSHNPLQPNTLRAVATYYSSLFGPVFTELNTEQHLHTLITFIAGELPRWDIVDMHPLPNDTAWFLTMQQAFRQAGMAVDSYYCFGNWYLQVRQRTYQQYFDALPSKLKNTVLRKTRFLQNAGRLHLKIAATIPDVEIVTAAYMNVYKNSWKHPEPFPDFIPGWLAESAAQGWLRLGLAYVDGKPVAAQIWLVQQGKASIYKLAYDQQFAHYSIGSILTAHMMQHVIDVDRVDEVDYLTGDEIYKQDWMSDRRERWGIIAFNRASVKGRLAYYYHLARRYAKRFHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0R1</accession>
    <name>A0A2S9H0R1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1544</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93543">
        <property type="protein sequence ID" value="PRC93543"/>
        <property type="gene ID" value="S2091_1544"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="150" mass="15837" checksum="1B57DF8363C8A697" modified="2018-07-18" version="1">MTINQMKSAILALAVAAATSISGCGSDKSEFVIIADDNCGINAPLGNTPFNRQTDLLPWGWAFDKATGTVPDQIFMQIISEDHKSSTKATMKRASRPDVAKAFGLPIDMAGYGGQIEVKNLPAGTYSVSIVQTSGNKTIVCTSPSKIILN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0R8</accession>
    <name>A0A2S9H0R8_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Aspartate--tRNA(Asp/Asn) ligase</fullName>
            <ecNumber evidence="7">6.1.1.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Aspartyl-tRNA synthetase</fullName>
            <shortName evidence="7">AspRS</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Non-discriminating aspartyl-tRNA synthetase</fullName>
            <shortName evidence="7">ND-AspRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">aspS</name>
        <name evidence="9" type="ORF">S2091_1572</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>ATP + L-aspartate + tRNA(Asx) = AMP + diphosphate + L-aspartyl-tRNA(Asx)</text>
            <dbReference type="Rhea" id="RHEA:18349"/>
            <dbReference type="Rhea" id="RHEA-COMP:9710"/>
            <dbReference type="Rhea" id="RHEA-COMP:9711"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78516"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.23"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.23" evidence="7"/>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93571">
        <property type="protein sequence ID" value="PRC93571"/>
        <property type="gene ID" value="S2091_1572"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004815">
        <property type="term" value="F:aspartate-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050560">
        <property type="term" value="F:aspartate-tRNA(Asn) ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006422">
        <property type="term" value="P:aspartyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00044">
        <property type="entry name" value="Asp_tRNA_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004364">
        <property type="entry name" value="Aa-tRNA-synt_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004524">
        <property type="entry name" value="Asp-tRNA-ligase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002312">
        <property type="entry name" value="Asp/Asn-tRNA-synth_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004115">
        <property type="entry name" value="GAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029351">
        <property type="entry name" value="GAD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004365">
        <property type="entry name" value="NA-bd_OB_tRNA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22594:SF5">
        <property type="entry name" value="PTHR22594:SF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02938">
        <property type="entry name" value="GAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00152">
        <property type="entry name" value="tRNA-synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01336">
        <property type="entry name" value="tRNA_anti-codon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01042">
        <property type="entry name" value="TRNASYNTHASP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55261">
        <property type="entry name" value="SSF55261"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00459">
        <property type="entry name" value="aspS_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="4 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 7 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="8">
        <location>
            <begin position="141"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="region of interest" description="Aspartate" evidence="7">
        <location>
            <begin position="198"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="174"/>
        </location>
        <ligand>
            <name>L-aspartate</name>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="220"/>
            <end position="222"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="220"/>
        </location>
        <ligand>
            <name>L-aspartate</name>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="229"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="457"/>
        </location>
        <ligand>
            <name>L-aspartate</name>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="491"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="498"/>
        </location>
        <ligand>
            <name>L-aspartate</name>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="543"/>
            <end position="546"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="site" description="Important for tRNA non-discrimination" evidence="7">
        <location>
            <position position="32"/>
        </location>
    </feature>
    <feature type="site" description="Important for tRNA non-discrimination" evidence="7">
        <location>
            <position position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC93571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="601" mass="67243" checksum="C84AA722BDAE3649" modified="2018-07-18" version="1">MSMRTHYCGQTTEAALDQTVSLCGWVHRRRDHGGVIFIDLRDREGLVQVVCAPEQAEVFAAAETVRNEFCLRITGVVRNRPEGTVNSNLKSGKIEVLCQVLEVLNASVTPPFQLDDDNLSETTRLTHRVLDLRRPQMQNNLRLRHKVTMEVRRYLDALGFIDVETPMLTKSTPEGARDYLVPSRVNAGQFFALPQSPQLFKQLLMVANFDRYYQITKCFRDEDLRADRQPEFTQIDCETSFMSEQEIRDLFEDMIRLIFKNCLSVDLDSQFPVMDYSTAMGMYGSDKPDMRVKLEFTELTSVMKDVDFKVFSGAANMVGGRVVGLRVPGGGAMPRSEIDAYTQFVSIYGAKGLAYIKVNDKAAGREGLQSPIVKNLHDAALAQIIELTGAQNGDLIFFGADKAKVVNDAIGALRVKIGHSDFGKSNGLFENVWKPLWVVDFPMFEYDEDSARWFACHHPFTAPKDGHEELLETDPGNCIAKAYDLVLNGWEMGGGSIRIHKADVQSKVFRALNIDAEEAQLKFGFLLDALQYGAPPHGGLAFGLDRIVTMMAGAESIRDVIAFPKTQRAQCLLTQAPSGVDEKQLRELHIRLRATEPVVKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0S0</accession>
    <name>A0A2S9H0S0_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 6">Glucose-1-phosphate thymidylyltransferase</fullName>
            <ecNumber evidence="4 6">2.7.7.24</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_1554</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>alpha-D-glucose 1-phosphate + dTTP + H(+) = diphosphate + dTDP-alpha-D-glucose</text>
            <dbReference type="Rhea" id="RHEA:15225"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37568"/>
            <dbReference type="ChEBI" id="CHEBI:57477"/>
            <dbReference type="ChEBI" id="CHEBI:58601"/>
            <dbReference type="EC" id="2.7.7.24"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 6">Belongs to the glucose-1-phosphate thymidylyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.24" evidence="4 6"/>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93553">
        <property type="protein sequence ID" value="PRC93553"/>
        <property type="gene ID" value="S2091_1554"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008879">
        <property type="term" value="F:glucose-1-phosphate thymidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045226">
        <property type="term" value="P:extracellular polysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02538">
        <property type="entry name" value="G1P_TT_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005907">
        <property type="entry name" value="G1P_thy_trans_s"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005835">
        <property type="entry name" value="NTP_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43532">
        <property type="entry name" value="PTHR43532"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00483">
        <property type="entry name" value="NTP_transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01207">
        <property type="entry name" value="rmlA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NTP_transferase" evidence="7">
        <location>
            <begin position="6"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC93553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="296" mass="33205" checksum="271B3B102055B6AF" modified="2018-07-18" version="1">MMKQRKGIILAGGSGTRLYPVTQAVSKQLLPVYDKPMIYYPLSTLMMAGIRDILIISTPQDTPRFEQLLGDGHEWGLNLQYAVQPSPDGLAQAFIIGKEFIGNSPSALVLGDNIFYGHNLDAQLSQAMQREHGATVFAYHVQDPERYGVVAFDAQGRATSLEEKPKNPQSNYAVTGLYFYDNQVVDIASSLKPSARGELEITDLNRIYLEREKLNVEIMGRGYAWLDTGTHESLMEASNFIQTIEHRQGLKICCPEEIAFRKNFINAEQLEKLAQPLAKNGYGQYLLRVLKEVVYP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0U8</accession>
    <name>A0A2S9H0U8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Response regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_1589</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93588">
        <property type="protein sequence ID" value="PRC93588"/>
        <property type="gene ID" value="S2091_1589"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="1"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="148"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC93588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="210" mass="23068" checksum="42AB9C9BADF63118" modified="2018-07-18" version="1">MLHIVDDDADLRDALVWMAKSRQLPCVAYASGEQFLGALASYGRNGSGTAAEHAAQFSFDPKGDCVLLDVRMAGISGIATFDLLAELPISKRLPVIFITGHGDVPMAVDALKRGAFDFFEKPFNDNALFDRVQEALELSRQAGEMAVVYQRLANLTTREREVLDLILLGKMNKLIADQLGISMRTVEVHRANIFDKMEVKTAVELAGLLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H117</accession>
    <name>A0A2S9H117_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 2">Adenylyl-sulfate kinase</fullName>
            <ecNumber evidence="1 2">2.7.1.25</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">APS kinase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">ATP adenosine-5'-phosphosulfate 3'-phosphotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Adenosine-5'-phosphosulfate kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">cysC</name>
        <name evidence="3" type="ORF">S2091_1557</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 2">Catalyzes the synthesis of activated sulfate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 2">
            <text>adenosine 5'-phosphosulfate + ATP = 3'-phosphoadenylyl sulfate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24152"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58243"/>
            <dbReference type="ChEBI" id="CHEBI:58339"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.25"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 2">Sulfur metabolism; hydrogen sulfide biosynthesis; sulfite from sulfate: step 2/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the APS kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.25" evidence="1 2"/>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93556">
        <property type="protein sequence ID" value="PRC93556"/>
        <property type="gene ID" value="S2091_1557"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00140">
        <property type="reaction ID" value="UER00205"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004020">
        <property type="term" value="F:adenylylsulfate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070814">
        <property type="term" value="P:hydrogen sulfide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000103">
        <property type="term" value="P:sulfate assimilation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02027">
        <property type="entry name" value="APSK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00065">
        <property type="entry name" value="Adenylyl_sulf_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002891">
        <property type="entry name" value="APS_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00455">
        <property type="entry name" value="apsK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 2 3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1 2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0808">Transferase</keyword>
    <feature type="active site" description="Phosphoserine intermediate" evidence="1">
        <location>
            <position position="122"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="48"/>
            <end position="55"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU004347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="211" mass="23632" checksum="DDB9A25879DD735A" modified="2018-07-18" version="1">MHITTRTIPVQNPNENNDKVCPTEHFTITPTDREKRQGHHSKVIWLTGLSGAGKSTIANALEIKLHFANKFTYILDGDNVRKSLNKDLGFDAPSRTENIRRISEVANMMREAGLIVIVTAISPFRIDREQAKKCIGSEHFIEVHISTPLQVCEQRDPKGLYKKSRSGQLSNMTGIDSPYELPENPAIAIDSSRTDIEASAELIFNLIYSSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H126</accession>
    <name>A0A2S9H126_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Bacterial extracellular solute-binding protein, family 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_1651</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93650">
        <property type="protein sequence ID" value="PRC93650"/>
        <property type="gene ID" value="S2091_1651"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001638">
        <property type="entry name" value="Solute-binding_3/MltF_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00497">
        <property type="entry name" value="SBP_bac_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015436223" evidence="2">
        <location>
            <begin position="24"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="domain" description="PBPb" evidence="3">
        <location>
            <begin position="36"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC93650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="262" mass="29611" checksum="AD8B30C4900F825B" modified="2018-07-18" version="1">MRSTYAPILALLLILGCVTSAKAEVPKELRVCGDLAEFPPFTYFVRNETQISQVVAGYNIDVLNEVLATSNRSAIVTLLPWKRCQAVAAQGQYDIVLDISKAPVREHDFAFTKVVYTLNTIYIYSMERPEPIINSTDDFKRFSFCIPIGWELTQFNIPVKSITGQPYSSKQAIEMLKVGRCDVAIYYKELLRGDRLIGSGGILNDPKIKYKLVPGLPKPEFFMAVSRALPYSDDLVQLLNSGIEQMKKTGEEERLLRLYNLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H164</accession>
    <name>A0A2S9H164_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1722</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93721">
        <property type="protein sequence ID" value="PRC93721"/>
        <property type="gene ID" value="S2091_1722"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015761287" evidence="1">
        <location>
            <begin position="19"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="212" mass="20567" checksum="C7C7FE82FEC6F5B8" modified="2018-07-18" version="1">MKFLKLTFAFVVASMVLAGCGGSINATIGGTVSGLLAGNSVGLTNNGTDAITVVFNSSGTNFTFDQKVSSGSSYNVVVTTQPTGLTCTVVNGSGTVAYSGGNVTDVQVTCSSGGTAANGVVSASITGLASGAQLILLDAVNNVPTDTLTVTGTAATAAGTALLQNFPTSLSVGSNYTVSVGTQPTGHTCTVTSASGTISSTTAAPSAIVTCQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H196</accession>
    <name>A0A2S9H196_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1637</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93636">
        <property type="protein sequence ID" value="PRC93636"/>
        <property type="gene ID" value="S2091_1637"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023187">
        <property type="entry name" value="Tscrpt_reg_MarR-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01047">
        <property type="entry name" value="MarR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00598">
        <property type="entry name" value="HTHMARR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00347">
        <property type="entry name" value="HTH_MARR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01117">
        <property type="entry name" value="HTH_MARR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50995">
        <property type="entry name" value="HTH_MARR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="1">
        <location>
            <begin position="1"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="140" mass="16103" checksum="63EE623CEFAC08A1" modified="2018-07-18" version="1">MSERYLRSIRLLAECMQQFEKQSGTFIRQLGLTHAQFDIIATLGNTTGMSCKELGEKTLITKGTLTGVLDRLIAKELISRTRSCQDRRHFFVCLTPKGEQVFTDTFPKVISMMQQRFDDYDVADFISLEQQLSKLKARLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1C3</accession>
    <name>A0A2S9H1C3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Outer membrane insertion C-terminal signal</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1744</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93743">
        <property type="protein sequence ID" value="PRC93743"/>
        <property type="gene ID" value="S2091_1744"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015717730" evidence="1">
        <location>
            <begin position="19"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="224" mass="24408" checksum="80773E0D53909E7C" modified="2018-07-18" version="1">MKKWFWMLSVLIAHTVLADEPVLSLNAGTTGFGVQMGYAFHSDLQARLGVNLLDVNTNRTPSDINYDLKLKLRTLDMLLDWYPLQGAFHLSGGVMLNGNKFTGVAQADGNQNYVIQGDVYNAAEAGAINAKIDYRTVAPYLGVGWDTAHVQQKGWGFNADLGVMFQGSANTSITNTGCTLGVVGGVNLCQNLDNDLAGERNTVEDKANKLRYLPVLRAGINYKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1D0</accession>
    <name>A0A2S9H1D0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ABC-2 family transporter protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_1400</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93791">
        <property type="protein sequence ID" value="PRC93791"/>
        <property type="gene ID" value="S2091_1400"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032688">
        <property type="entry name" value="ABC2_membrane_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12679">
        <property type="entry name" value="ABC2_membrane_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="184"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="232"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="273"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="308"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="359"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC93791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="386" mass="42936" checksum="F0447A83A9CA3F2F" modified="2018-07-18" version="1">MKLMLSIAYKELVDALRDKRTMLMVFMVTIFGMPFMMVMMSEMANRFETQAEKKVIWIAGIKHAPELQNFVERQGYQIKDAPVDYEHQLQTKTLIDPVLVVSDDFQEKLAQGDRPTVFIVMDVANQDSQTGVAPLRRLMQGYSSEQAGLNLAMRGVSPDILNVIDVKERHLSRTADSGAQLKSVMSMMLMFTMISAGLYAAIDTSAGERERGSLEPLMMNPVSSWAFTVGKWIAVGTLTMMVVVFSVLSIFPASLLIRNETIKIMLQFSSAEMLLMILVLLPLGLCLAAVQIAIAINGKSHKEAQARCTILLVAAPLVSMIGMFKQGADPVWYKWVPLLSQNQLMGKILNNEVVSSADMFAPVLTCALITFAALWYTSKKMRSILM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1D5</accession>
    <name>A0A2S9H1D5_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Nucleotide-binding protein S2091_1401</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1401</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Displays ATPase and GTPase activities.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the RapZ-like family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93792">
        <property type="protein sequence ID" value="PRC93792"/>
        <property type="gene ID" value="S2091_1401"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00636">
        <property type="entry name" value="RapZ_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005337">
        <property type="entry name" value="RapZ-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30448">
        <property type="entry name" value="PTHR30448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03668">
        <property type="entry name" value="ATP_bind_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005052">
        <property type="entry name" value="P-loopkin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="8"/>
            <end position="15"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="57"/>
            <end position="60"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="287" mass="32316" checksum="90E454B4CA713748" modified="2018-07-18" version="1">MRIFLISGISGSGKSVALNVLEDTGFFCVDNLPPTLLPELISTLTQDGIQAAAIAIDARSANSLNGLINSIQLLKAAGHQLDLLFLTAKTESLIARFSETRRSHPLSHRLLPGQNPNDPRTLIECIQTERKMLNEMEEIADVIDTSGLKTSQLRSWIRELINIERSNITILFESFAFKVGVPLNADLMFDVRTLPNPHYDINLRPLTGQDLPVQLFLQDQPEAQEMLNDISQFIEKWLPSFKHDNRSYLTICIGCTGGQHRSVYMVEQLAQHFKTTEQVVIRHRELT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1I8</accession>
    <name>A0A2S9H1I8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transglycosylase SLT domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1463</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93854">
        <property type="protein sequence ID" value="PRC93854"/>
        <property type="gene ID" value="S2091_1463"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023346">
        <property type="entry name" value="Lysozyme-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008258">
        <property type="entry name" value="Transglycosylase_SLT_dom_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01464">
        <property type="entry name" value="SLT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53955">
        <property type="entry name" value="SSF53955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SLT" evidence="1">
        <location>
            <begin position="34"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="167" mass="18641" checksum="AA439F5D689229D3" modified="2018-07-18" version="1">MSFISKRWFILLRWIIFTLLVMLVSSTDSAYASCFVSAGKKYTIDPQLLEAIAQVESSMNPQALNRNRDGSEDIGLMQINSSHLVRLRKDGITRQQLLDDACLSVMIGAEILSGFIGQFGYTWRAVGAYNAGGNPGCDLLRELYAARVVREYRRLRGRPELAASGKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1P1</accession>
    <name>A0A2S9H1P1_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Effector protein BipC</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_1479</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the invasin protein C family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93870">
        <property type="protein sequence ID" value="PRC93870"/>
        <property type="gene ID" value="S2091_1479"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005427">
        <property type="entry name" value="BacInvasinC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09599">
        <property type="entry name" value="IpaC_SipC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="217"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="217"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC93870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="382" mass="39888" checksum="AECFFBADD8594126" modified="2018-07-18" version="1">MTTVAINNQVSFPLQGGVKVSGLLGANDVANAGIGNKKSDPFPLALVRFDEDGDSDNARIRNDLSNALVAMSPERKGRVISNLTDMAHSAAVAGDSKVVDALKSKLPDVEKEARNGNSFDHLLELLFMLITLLGQANTARKNSAAKFGEIAFKQVQIAGANNIAAASANLAGSLSGMVIGVATGGVGFGVSAKATGNQVKNIKTNRRDTLDLRQKNNTLSNAINRPTSPSNGQSAQDKVRKLDAQGKELHVQENLPGLTSSERAVLSQPLERTNALIDSKQMVMDTNTQQFALQQQGGHLISSYAMPLANVAQAGAGVDAASKTSTATIVTAGGNAATTMQHSDDEISEQTNGLLAKMFALINSLSKANVNTLNAVSQSIKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1P2</accession>
    <name>A0A2S9H1P2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1486</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93877">
        <property type="protein sequence ID" value="PRC93877"/>
        <property type="gene ID" value="S2091_1486"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="102" mass="10749" checksum="82F9B95CE39EC05D" modified="2018-07-18" version="1">MNNMAISGVGESGGLAAVNITPQQITPLSLDDRLRDAFASTSVATQAEYANIMGMANDAKYLSTPGGLFELQVHLGEYKQHVEVISALTRKGVAAAETLLRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H219</accession>
    <name>A0A2S9H219_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 15">ATP phosphoribosyltransferase</fullName>
            <shortName evidence="15">ATP-PRT</shortName>
            <shortName evidence="15">ATP-PRTase</shortName>
            <ecNumber evidence="6 15">2.4.2.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">hisG</name>
        <name evidence="17" type="ORF">S2091_1181</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14 15">Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 15">
            <text>1-(5-phospho-beta-D-ribosyl)-ATP + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + ATP</text>
            <dbReference type="Rhea" id="RHEA:18473"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="ChEBI" id="CHEBI:73183"/>
            <dbReference type="EC" id="2.4.2.17"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 15">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 1/9.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5 15">Heteromultimer composed of HisG and HisZ subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 15">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="15">Lacks the C-terminal regulatory region which is replaced by HisZ.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 15">Belongs to the ATP phosphoribosyltransferase family. Short subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.17" evidence="6 15"/>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94008">
        <property type="protein sequence ID" value="PRC94008"/>
        <property type="gene ID" value="S2091_1181"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00006"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003879">
        <property type="term" value="F:ATP phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd13595">
        <property type="entry name" value="PBP2_HisGs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01018">
        <property type="entry name" value="HisG_Short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013820">
        <property type="entry name" value="ATP_PRibTrfase_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018198">
        <property type="entry name" value="ATP_PRibTrfase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001348">
        <property type="entry name" value="ATP_PRibTrfase_HisG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024893">
        <property type="entry name" value="ATP_PRibTrfase_HisG_short"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21403">
        <property type="entry name" value="PTHR21403"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01634">
        <property type="entry name" value="HisG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00070">
        <property type="entry name" value="hisG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01316">
        <property type="entry name" value="ATP_P_PHORIBOSYLTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 15" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="12 15" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 15" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 15 17" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="13 15" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="11 15" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 15 17" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HisG" evidence="16">
        <location>
            <begin position="54"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00011946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00024861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF01634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="PRC94008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="216" mass="23289" checksum="EBA32CCECC3A153E" modified="2018-07-18" version="1">MSAQLTLALSKGRIFDDTLPLLKAAGISVLEDPQTSRKLILATSNPALRVIIVRASDVPTYVQYGAADFGVAGKDVLIEHGGLGLYQPVDLQIAACRMSVAVAQGFDYAKAIRQGARLRVATKYVEIARRHFASKGVHVDLIKLYGSMELAPLIGLSDVIVDLVSTGNTLRANHLVEVEEIMDISSRLIVNQAALKLKRESLQPILAAFEAASLQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H224</accession>
    <name>A0A2S9H224_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Dinuclear metal center protein, YbgI/SA1388 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1166</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GTP cyclohydrolase I type 2/NIF3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC93993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93993">
        <property type="protein sequence ID" value="PRC93993"/>
        <property type="gene ID" value="S2091_1166"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002678">
        <property type="entry name" value="DUF34/NIF3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036069">
        <property type="entry name" value="DUF34/NIF3_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13799">
        <property type="entry name" value="PTHR13799"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01784">
        <property type="entry name" value="NIF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102705">
        <property type="entry name" value="SSF102705"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00486">
        <property type="entry name" value="YbgI_SA1388"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="257" mass="28382" checksum="B8AD0DBE0ECFCCF2" modified="2018-07-18" version="1">MNLHKKLVSRDELSQFLADKLQISRINDYCPNGLQVEGVEQIKVVVSGVTASLALIEAAIELQADCLIVHHGYFWRGENPCLVGPKYQRIKKLINHNINLYGYHLPLDLHPEWGNNVQLARQLELVAEGTFADQSLASYGYINNSELRTVGDLSRWIEAKLGRTPLLIGEPDQPLGRIAWCTGAAQNFLDDAINIGATVYLSGEISEPTVHLARESGVAYLACGHHATERYGVQALGQAIAEQFGVIHHFVDIPNPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H251</accession>
    <name>A0A2S9H251_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1238</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94065">
        <property type="protein sequence ID" value="PRC94065"/>
        <property type="gene ID" value="S2091_1238"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024453">
        <property type="entry name" value="Peptidase_C92"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05708">
        <property type="entry name" value="Peptidase_C92"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="SSF54001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="244" mass="27401" checksum="8C8AFA709A9AF41F" modified="2018-07-18" version="1">MFINTNSFHQSKFNPIYAFTLIAAVLFYPLHANAVQLPDVQNPTSQSTSIDQIAKTLKVGDLIFIRVSARPFREVADATGTWTNHVGIVTDIDGSEPLIGESTFPFSRTTTLTKFVARSEQGHVAVTRLKSDLSPQQIQMIQRGVKERSGIFYDTGFNLHSHKEFCSRFVYEVVKDATGVSIGKIETFKEMLASRPDINLGFWKVWYFGQIPWERETITPASLLNSPELNPIFNGNVDTTNHLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2C7</accession>
    <name>A0A2S9H2C7_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">30S ribosomal protein S4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rpsD</name>
        <name evidence="11" type="ORF">S2091_1291</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.</text>
    </comment>
    <comment type="function">
        <text evidence="6">With S5 and S12 plays an important role in translational accuracy.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the universal ribosomal protein uS4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94118">
        <property type="protein sequence ID" value="PRC94118"/>
        <property type="gene ID" value="S2091_1291"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01306_B">
        <property type="entry name" value="Ribosomal_S4_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022801">
        <property type="entry name" value="Ribosomal_S4/S9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001912">
        <property type="entry name" value="Ribosomal_S4/S9_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005709">
        <property type="entry name" value="Ribosomal_S4_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018079">
        <property type="entry name" value="Ribosomal_S4_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11831">
        <property type="entry name" value="PTHR11831"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11831:SF4">
        <property type="entry name" value="PTHR11831:SF4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00163">
        <property type="entry name" value="Ribosomal_S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01479">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01390">
        <property type="entry name" value="Ribosomal_S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00363">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01017">
        <property type="entry name" value="rpsD_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00632">
        <property type="entry name" value="RIBOSOMAL_S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 6 7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 6" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_S4" evidence="10">
        <location>
            <begin position="3"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="domain" description="S4" evidence="9">
        <location>
            <begin position="97"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="34"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM01390"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC94118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="207" mass="23236" checksum="C6A45CFBD686B6FB" modified="2018-07-18" version="1">MARYIGPKAKLSRREGTDLFLKSARRSLDSKCKLDVKPGQHGAKSGARTSDFGNQLREKQKVKRMYGVLERQFRRYFAEADRRKGNTGETLLKLLECRLDNVCYRMGFGSTRAEARQLVSHKAFTVNSIVVNIASYQVKAGDVVAVREKSKKQVRIAEALSLAEQIGMPSWVSVDAKKMEGTFKSAPDRSDIAADVNESLIVELYSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2D8</accession>
    <name>A0A2S9H2D8_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7 8">Elongation factor Tu</fullName>
            <shortName evidence="7">EF-Tu</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">tuf</name>
        <name evidence="10" type="ORF">S2091_1317</name>
        <name evidence="11" type="ORF">S2091_1336</name>
    </gene>
    <organism evidence="10 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94144">
        <property type="protein sequence ID" value="PRC94144"/>
        <property type="gene ID" value="S2091_1317"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94163">
        <property type="protein sequence ID" value="PRC94163"/>
        <property type="gene ID" value="S2091_1336"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01884">
        <property type="entry name" value="EF_Tu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03697">
        <property type="entry name" value="EFTU_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00118_B">
        <property type="entry name" value="EF_Tu_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041709">
        <property type="entry name" value="EF-Tu_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033720">
        <property type="entry name" value="EFTU_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009001">
        <property type="entry name" value="Transl_elong_EF1A/Init_IF2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004541">
        <property type="entry name" value="Transl_elong_EFTu/EF1A_bac/org"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004160">
        <property type="entry name" value="Transl_elong_EFTu/EF1A_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03143">
        <property type="entry name" value="GTP_EFTU_D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50465">
        <property type="entry name" value="SSF50465"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00485">
        <property type="entry name" value="EF-Tu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 7 10" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="5 7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="9">
        <location>
            <begin position="10"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="19"/>
            <end position="26"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="81"/>
            <end position="85"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="136"/>
            <end position="139"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC94144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC94163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="396" mass="42955" checksum="B6DB21370C588856" modified="2018-07-18" version="1">MAKSKFERTKPHVNVGTIGHVDHGKTTLTAAIATVLSKKFGGEAKDYSQIDNAPEEKARGITINTSHVEYETAVRHYAHVDCPGHADYVKNMITGAAQMDGAILVCSAADGPMPQTREHILLARQVGVPYIIVFLNKCDMVDDAELLELVEMEVRELLSKYDFPGDDLPIIQGSAKLALEGDKGPLGEEAIMKLAEALDTYIPTPERAVDGAFLLPVEDVFSISGRGTVVTGRIERGIVKVGESLEIIGITDTAVTTCTGVEMFRKLLDQGQAGDNVGVLLRGTKREDVQRGQVLAKPGTIKPHNHFTGEIYVLSKDEGGRHTPFFNNYRPQFYFRTTDVTGSIELPADKEMVMPGDNVSITVKLINPIAMEEGLRFAIREGGRTVGAGVVAKIIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2F5</accession>
    <name>A0A2S9H2F5_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">50S ribosomal protein L1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">rplA</name>
        <name evidence="10" type="ORF">S2091_1332</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.</text>
    </comment>
    <comment type="function">
        <text evidence="8">Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 8 9">Belongs to the universal ribosomal protein uL1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94159">
        <property type="protein sequence ID" value="PRC94159"/>
        <property type="gene ID" value="S2091_1332"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00403">
        <property type="entry name" value="Ribosomal_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01318_B">
        <property type="entry name" value="Ribosomal_L1_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005878">
        <property type="entry name" value="Ribosom_L1_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002143">
        <property type="entry name" value="Ribosomal_L1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023674">
        <property type="entry name" value="Ribosomal_L1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028364">
        <property type="entry name" value="Ribosomal_L1/biogenesis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016095">
        <property type="entry name" value="Ribosomal_L1_3-a/b-sand"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023673">
        <property type="entry name" value="Ribosomal_L1_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00687">
        <property type="entry name" value="Ribosomal_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002155">
        <property type="entry name" value="Ribosomal_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56808">
        <property type="entry name" value="SSF56808"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01169">
        <property type="entry name" value="rplA_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01199">
        <property type="entry name" value="RIBOSOMAL_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0678">Repressor</keyword>
    <keyword evidence="7 8 9" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="6 8 9" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5 8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 8" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="4 8" id="KW-0810">Translation regulation</keyword>
    <keyword evidence="8" id="KW-0820">tRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01318"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC94159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="231" mass="24411" checksum="F2D6293D8C441EE7" modified="2018-07-18" version="1">MAKLSKRAKLIKSKIDRTKVYPFDNAVALIRECATAKFNESFDVAIQLGVDPKKSDQVVRGSVVLPAGTGRTVRVAVFATGEKAEQAKAAGADVVGMEDLAERIKAGDMPFDIVIASPDTMRIVGTLGQILGPRGLMPNPKVGTVTPDVATAVKNAKAGQVQYRTDKAGIIHSTIGRKSFADADLKANLMALIEALQKAKPTSSKGVYLRRVALSSTMGAGVRVDHINLAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2G1</accession>
    <name>A0A2S9H2G1_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5 7">30S ribosomal protein S12</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpsL</name>
        <name evidence="9" type="ORF">S2091_1320</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4 5 7">Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.</text>
    </comment>
    <comment type="function">
        <text evidence="1 5 7">With S4 and S5 plays an important role in translational accuracy.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5 7">Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 5 6">Belongs to the universal ribosomal protein uS12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94147">
        <property type="protein sequence ID" value="PRC94147"/>
        <property type="gene ID" value="S2091_1320"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03368">
        <property type="entry name" value="Ribosomal_S12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00403_B">
        <property type="entry name" value="Ribosomal_S12_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006032">
        <property type="entry name" value="Ribosomal_S12/S23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005679">
        <property type="entry name" value="Ribosomal_S12_bac"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11652">
        <property type="entry name" value="PTHR11652"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00164">
        <property type="entry name" value="Ribosom_S12_S23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002133">
        <property type="entry name" value="Ribosomal_S12/S23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01034">
        <property type="entry name" value="RIBOSOMALS12"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00981">
        <property type="entry name" value="rpsL_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00055">
        <property type="entry name" value="RIBOSOMAL_S12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 6 9" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5 7" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="5 7" id="KW-0820">tRNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="104"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00024962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC94147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="127" mass="14103" checksum="3485671DFEFC5144" modified="2018-07-18" version="1">MPTINQLIRQPRVSARVKSKSPALENSPQKRGVCTRVYTTTPKKPNSALRKVAKVRLTNGFEVISYIGGEGHNLQEHSVVLLRGGRVKDLPGVRYHMVRGALDTQGVKDRKQARSKYGSKRAKAAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2K5</accession>
    <name>A0A2S9H2K5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Phosphate starvation-inducible protein PhoH predicted ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_0811</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PhoH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94190">
        <property type="protein sequence ID" value="PRC94190"/>
        <property type="gene ID" value="S2091_0811"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003714">
        <property type="entry name" value="PhoH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02562">
        <property type="entry name" value="PhoH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PhoH" evidence="4">
        <location>
            <begin position="130"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC94190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="355" mass="38786" checksum="4F780C564374DACE" modified="2018-07-18" version="1">MKNKTDVLTFSPEQPLDNTKLAALCGPMDANLRQISAALDVSLFRRGDKFIVSGSNAEQAVELLEKFYNSNKKIISVDEVQLALVEQRSQGGGAASAALPAILSKVSDVSNHAPSEIISPILKTRRTDLRGRTPHQIEYLKSIMEHDVTFGIGPAGTGKTYLAVACAVDALERDAVKRIVLTRPAVEAGERLGFLPGDLAQKVDPYLRPLYDALYDLLGFDRTQKMFEKQAIEIAPLAYMRGRTLNHAFVILDEAQNTTPEQMKMFLTRIGFGSKAVITGDVTQIDLQRGQKSGLVDANTVLSDVRGIAFTRFSSIDVVRHPLVARIVDAYENASAMNTTISLAPTKVSKNGRKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2W7</accession>
    <name>A0A2S9H2W7_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HTH cro/C1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0931</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94310">
        <property type="protein sequence ID" value="PRC94310"/>
        <property type="gene ID" value="S2091_0931"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041413">
        <property type="entry name" value="MLTR_LBD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17765">
        <property type="entry name" value="MLTR_LBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="28"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="286" mass="32136" checksum="E9F303EEBE317612" modified="2018-07-18" version="1">MSASNAVTDTSGGHAVSNPYFKDFASALRYWRDKRGFSQLRLSTVSNISQRHISFLESCRAQPSKELILKMGVTLDIPLRQRNQMLLAAGFAPAYQERKMSDPELESVRYALNFMLAQQAPYPALVVDRLWNLVMSNEPALMMIKWLLDIPDSQPVSTEGLNVIKMMLDPSSLRPYLVNWEHICADLLHWIQREAMSDGPGSESTLLLQELATIPGVQSAKNVPNLDTRALPFMPVTIRKNDVTLNLFTSITTMGTPHDVTVHELRVESFFPADDATAAWFKLKAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2X6</accession>
    <name>A0A2S9H2X6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0960</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94339">
        <property type="protein sequence ID" value="PRC94339"/>
        <property type="gene ID" value="S2091_0960"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="79" mass="8187" checksum="5D4894AB31692651" modified="2018-07-18" version="1">MIMSIAAEHGVSISKGIAADLLLTFTATMVGRTASQFLVGWIPVAGNIINASTAASVTEVIGWAANAYFEKTEIASKSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H397</accession>
    <name>A0A2S9H397_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1069</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94448">
        <property type="protein sequence ID" value="PRC94448"/>
        <property type="gene ID" value="S2091_1069"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SSF52091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="469" mass="52211" checksum="AB2D75809A831EC7" modified="2018-07-18" version="1">MIFSIFGKKNGGKKTSETDQKSAKDSLLTTTGLTANTSADFANSIMAQRHIARATERKIDAIEYEMSRDIIKKKIEPQQEPVNSQQPDANINLFDDDNTIDHKKYPNQTDNFEATMPLLGAVTEYLLGSSTEALASHSSLENIPALEEAAILFASEQFEAAELILQNLIHTENYNALNPSAWLMLFDLYQITNNQVKFEQLSLDYVSKLEISAPIWVTAQTQSAPKKEKGFVPGVSFSGKLNAQINKQIDKLNSLAKQHQQMRLEFVRITEVDVMGCELLLKGFQSLKKSKQELTVVGAHDLIKYVRALVAVGRRDESEAPWLLLLELLQLINDEAAFEEASIDYCITYEVSPPSFEAPKNKATAASVGISIEFVEADRFLLPKIIDGNTDVLIGNIATFAQQHNSVQLDCSQLDRIDFSSCGQLLSGLIPLSKQLNVSIEFHDVNHLVIALLNAMGFKNIAMIFPRKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3A6</accession>
    <name>A0A2S9H3A6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Membrane-bound metallopeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_1079</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94458">
        <property type="protein sequence ID" value="PRC94458"/>
        <property type="gene ID" value="S2091_1079"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011055">
        <property type="entry name" value="Dup_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016047">
        <property type="entry name" value="Peptidase_M23"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01551">
        <property type="entry name" value="Peptidase_M23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51261">
        <property type="entry name" value="SSF51261"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015698145" evidence="3">
        <location>
            <begin position="25"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M23" evidence="4">
        <location>
            <begin position="347"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="23"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="274"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="180"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="283"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC94458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="447" mass="49159" checksum="81EFF9F19AB25EFE" modified="2018-07-18" version="1">MPKSYAAKLAALALVLAWFTPSWSASPGRDEQKRTAESEHAELRKKLSDLKQDILTTESAKQRAEDSLADSEAAISNANRKLVGLSAEQQQTQQKLTDLAGQQQKLQQQVEQQKKQFSALLRQQYQTGNSDRIQLLLSGDNPNRINRDLQYLGYLSQSQNKLISQLRDNLAAVDKNKLATEQAKQDLDDIAEEQQQQKSDLVKEQTKRAGLIKQLSSKLSAQRKEAGQLQKNEQRLATLVDKLNQLIAEQRKAEQAQQEKRRLAQLALEAKRKAATEAKPAKDAGKSSSTKSGSGTITESAPIQVTKTPEASSDNSQFAQLKGRLRLPTKGELSAKFGSQRGEGTAWKGLFIRANEGAEIKAVASGKVIFAEWLRGFGNLIILDHGSQYMSIYGNNQSVLKQAGDTVSAGEVIATVGNSGGNEQSGLYFELRFQGKAIDPLSWINLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3Q8</accession>
    <name>A0A2S9H3Q8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0611</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94608">
        <property type="protein sequence ID" value="PRC94608"/>
        <property type="gene ID" value="S2091_0611"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015548247" evidence="2">
        <location>
            <begin position="22"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="99"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="132" mass="13704" checksum="FA4EB14DEFED72D1" modified="2018-07-18" version="1">MLSRIPTTLSKIVILSALACASLLLGCDKPEATTQVDPEVVAKENDARATGSACRQAGRALEDCYSMNPTAPRAAVFSGWKDMNDYMRENKMEVVKPEAEMAKAAGASSASATDEAASASASSSASGKGKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3R9</accession>
    <name>A0A2S9H3R9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0637</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94634">
        <property type="protein sequence ID" value="PRC94634"/>
        <property type="gene ID" value="S2091_0637"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025234">
        <property type="entry name" value="DUF4177"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13783">
        <property type="entry name" value="DUF4177"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="63" mass="7367" checksum="A9A02E3813266CC8" modified="2018-07-18" version="1">MNKWEYKIIKVNAKREFWTSQFDIKAIEVKLNELGQQGWELVSIEGLNNRYATAPVLTVKRVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3V8</accession>
    <name>A0A2S9H3V8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="9">ABC-type sugar transport systems ATPase component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_0661</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94658">
        <property type="protein sequence ID" value="PRC94658"/>
        <property type="gene ID" value="S2091_0661"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008643">
        <property type="term" value="P:carbohydrate transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03301">
        <property type="entry name" value="ABC_MalK_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015855">
        <property type="entry name" value="ABC_transpr_MalK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008995">
        <property type="entry name" value="Mo/tungstate-bd_C_term_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013611">
        <property type="entry name" value="Transp-assoc_OB_typ2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08402">
        <property type="entry name" value="TOBE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50331">
        <property type="entry name" value="SSF50331"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="5" id="KW-1278">Translocase</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="8">
        <location>
            <begin position="4"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="37"/>
            <end position="44"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC94658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="367" mass="40068" checksum="ECB2B548F218FAC1" modified="2018-07-18" version="1">MASVSFKNISKHYTKDESVIKGVDFTIEDGEFVVFVGPSGCGKSTLLRMVAGLEDITDGEIYIGDVLANDLHASKRGVAMVFQSYALYPHMTVQQNMGFALKMASAPKAEIELRVRKAAEILQITHLLDRKPKALSGGQRQRVAIGRAIVRQPKVFLFDEPLSNLDASLRQNMRIELSKLHHELGTTMIYVTHDQVEAMTLADRIVVFNAGKVQQVGSPLDLYDNPCNLFVAGFLGAPRINLLKGRLIETGNASAEIILPGGQNLFAAVDASSGVKDEAVTLGIRPEHLQLSSASEAGSIAAKVVLIEHLGDQILAYLRIAGVAEELCMKLSVHKTNLRYDDTVHITLPASNCMLFDKTDEAFVRLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3Z1</accession>
    <name>A0A2S9H3Z1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nucleoside-diphosphate-sugar epimerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0702</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94699">
        <property type="protein sequence ID" value="PRC94699"/>
        <property type="gene ID" value="S2091_0702"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="1">
        <location>
            <begin position="10"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="326" mass="35614" checksum="F85FD55BA24621B8" modified="2018-07-18" version="1">METTATRKTALILGITGGFGSAVANSLAARGWQVRALHRNPEAGLAMLPAYDIEWRLGDAMNQVDVCAAAQGVDLIVHGLNPPKYQRWRELAIPMLANSIVAAKASGARLVFPGNVYLYGDDAGDVVNENSPRNPITEKGKIRLEMEQMIAEGARHGARAIIVRAGDFFGPGGQTSSWFGSAMIKPGKPVRSVIYPGQPEIAHGWAFLPDVAETVARLAELEADLPDIEIYHFGGHWLASASAMMAAIQRVVGRKVPLRTLPWPLMKLLTPFSGLMRELMEMRYLWQKPLRLDNSKLLRVLGEEPHTPLDEAMRITLIGLGCTPSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H425</accession>
    <name>A0A2S9H425_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0730</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94727">
        <property type="protein sequence ID" value="PRC94727"/>
        <property type="gene ID" value="S2091_0730"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021994">
        <property type="entry name" value="DUF3592"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12158">
        <property type="entry name" value="DUF3592"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="113"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="134" mass="15596" checksum="A54C77EFCA63CA1A" modified="2018-07-18" version="1">MLFFCVVLVGAACIVSRPLLQSLYWSFEERTWPTVTGTMENSDGFSYTVNGTLHYNDVSTRYGHMMYKLPAARSRLWNAHPERVEGFKLQVYYDPNNPQISVIDRRRLTIEDYIILAFSFVLWYVAIMAILLTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4P5</accession>
    <name>A0A2S9H4P5_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Exodeoxyribonuclease 7 large subunit</fullName>
            <ecNumber evidence="5">3.1.11.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Exodeoxyribonuclease VII large subunit</fullName>
            <shortName evidence="5">Exonuclease VII large subunit</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">xseA</name>
        <name evidence="10" type="ORF">S2091_0106</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>Exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield nucleoside 5'-phosphates.</text>
            <dbReference type="EC" id="3.1.11.6"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="5">Heterooligomer composed of large and small subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5 6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the XseA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.11.6" evidence="5"/>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94911">
        <property type="protein sequence ID" value="PRC94911"/>
        <property type="gene ID" value="S2091_0106"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009318">
        <property type="term" value="C:exodeoxyribonuclease VII complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008855">
        <property type="term" value="F:exodeoxyribonuclease VII activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006308">
        <property type="term" value="P:DNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04489">
        <property type="entry name" value="ExoVII_LU_OBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00378">
        <property type="entry name" value="Exonuc_7_L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003753">
        <property type="entry name" value="Exonuc_VII_L"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020579">
        <property type="entry name" value="Exonuc_VII_lsu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025824">
        <property type="entry name" value="OB-fold_nuc-bd_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30008">
        <property type="entry name" value="PTHR30008"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02601">
        <property type="entry name" value="Exonuc_VII_L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13742">
        <property type="entry name" value="tRNA_anti_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00237">
        <property type="entry name" value="xseA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5 6" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="3 5 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5 6" id="KW-0540">Nuclease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="tRNA_anti_2" evidence="9">
        <location>
            <begin position="13"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="domain" description="Exonuc_VII_L" evidence="8">
        <location>
            <begin position="128"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="269"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="345"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF13742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC94911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="448" mass="50116" checksum="BAA997979373F6D6" modified="2018-07-18" version="1">MQTDSIFAPQVVTVSELNQTVARLLERSIPLCWISGEVSNFTRATSGHWYFTLKDAHAQVRSVMFKSRAMGADFIPREGEKVEVRATVTLYAPRGDYQLSVEGIRRAGMGNLYEAFLQLKQKLSNAGLFDADRKQALPSFPTCIGIVTSPQAAALRDILITLQRRAPHVRVIIYPTPVQGSGSAVKITQAIELAVARRECDVLIVARGGGSIEDLWSFNDEQVAYAIAQCPIPVIAGIGHETDFTIADFVADLRAPTPTAAAEIAVSARSDLMQQLENSTAKLRRALRRQLDENNQTLDNFSRRLISPIAYIRSERLKLSGMQRQVRHAFETSKRESFFQFDRLKQKLIKQAPNLANKKNQLQQLTQQLQHSAHQQLTLRQQGVHNLNLQLELLNPQRTLERGYAIILDKQGKIIRKPKQFQANSNITVKLAEGEVDLGITSVQQNLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4Q9</accession>
    <name>A0A2S9H4Q9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lipopolysaccharide heptosyltransferase I</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0118</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94923">
        <property type="protein sequence ID" value="PRC94923"/>
        <property type="gene ID" value="S2091_0118"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008920">
        <property type="term" value="F:lipopolysaccharide heptosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009244">
        <property type="term" value="P:lipopolysaccharide core region biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03789">
        <property type="entry name" value="GT9_LPS_heptosyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002201">
        <property type="entry name" value="Glyco_trans_9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011908">
        <property type="entry name" value="LipoPS_heptosylTferase-I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01075">
        <property type="entry name" value="Glyco_transf_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02193">
        <property type="entry name" value="heptsyl_trn_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="325" mass="35509" checksum="3CD321D38EC91D6A" modified="2018-07-18" version="1">MKVLLIRVSSMGDVLHNMPIVADILRNFPHAQIDWVVEENFVELVRLNPNVHKIIPFALRRWRKGLLSASVRAEMSAFKKTLRLETYDVILDTQGLLKTGVIMGLAQGGAKVGLANGTEGSGYEAASRIFHTLSVPVGIHTHAVLRGRIVAAHALGYMDKIENVAPDFGLLAPNPDLQPDWLPQNDYAVFFHGTAGAAKKWPAHDWITLGKHLNARNYPILLAWGNRTEQLEAEQLASHIPNAQVLPKLSMMEAIILAQRAAIVIGVDTGLTHIAAAYCRPTVEIYSASPRWKTEGNWSDKIINLGDKGAPPGVADVIAAVDSLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4R3</accession>
    <name>A0A2S9H4R3_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Coenzyme A biosynthesis bifunctional protein CoaBC</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">DNA/pantothenate metabolism flavoprotein</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Phosphopantothenoylcysteine synthetase/decarboxylase</fullName>
            <shortName evidence="3">PPCS-PPCDC</shortName>
        </alternativeName>
        <domain>
            <recommendedName>
                <fullName evidence="3">Phosphopantothenoylcysteine decarboxylase</fullName>
                <shortName evidence="3">PPC decarboxylase</shortName>
                <shortName evidence="3">PPC-DC</shortName>
                <ecNumber evidence="3">4.1.1.36</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="3">CoaC</fullName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="3">Phosphopantothenate--cysteine ligase</fullName>
                <ecNumber evidence="3">6.3.2.5</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="3">CoaB</fullName>
            </alternativeName>
            <alternativeName>
                <fullName evidence="3">Phosphopantothenoylcysteine synthetase</fullName>
                <shortName evidence="3">PPC synthetase</shortName>
                <shortName evidence="3">PPC-S</shortName>
            </alternativeName>
        </domain>
    </protein>
    <gene>
        <name evidence="3" type="primary">coaBC</name>
        <name evidence="7" type="ORF">S2091_0061</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.</text>
    </comment>
    <comment type="function">
        <text evidence="4">Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3 4">
            <text>(R)-4'-phosphopantothenate + CTP + L-cysteine = CMP + diphosphate + H(+) + N-[(R)-4-phosphopantothenoyl]-L-cysteine</text>
            <dbReference type="Rhea" id="RHEA:19397"/>
            <dbReference type="ChEBI" id="CHEBI:10986"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <dbReference type="ChEBI" id="CHEBI:59458"/>
            <dbReference type="ChEBI" id="CHEBI:60377"/>
            <dbReference type="EC" id="6.3.2.5"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3 4">
            <text>H(+) + N-[(R)-4-phosphopantothenoyl]-L-cysteine = (R)-4'-phosphopantetheine + CO2</text>
            <dbReference type="Rhea" id="RHEA:16793"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:59458"/>
            <dbReference type="ChEBI" id="CHEBI:61723"/>
            <dbReference type="EC" id="4.1.1.36"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
        <text evidence="3">Binds 1 FMN per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 4">Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 2/5.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 4">Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 3/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">In the C-terminal section; belongs to the PPC synthetase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.36" evidence="3"/>
    <dbReference type="EC" id="6.3.2.5" evidence="3"/>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94866">
        <property type="protein sequence ID" value="PRC94866"/>
        <property type="gene ID" value="S2091_0061"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00241">
        <property type="reaction ID" value="UER00353"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004632">
        <property type="term" value="F:phosphopantothenate--cysteine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004633">
        <property type="term" value="F:phosphopantothenoylcysteine decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015937">
        <property type="term" value="P:coenzyme A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015941">
        <property type="term" value="P:pantothenate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1950">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02225">
        <property type="entry name" value="CoaBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035929">
        <property type="entry name" value="CoaB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005252">
        <property type="entry name" value="CoaBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007085">
        <property type="entry name" value="DNA/pantothenate-metab_flavo_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036551">
        <property type="entry name" value="Flavin_trans-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003382">
        <property type="entry name" value="Flavoprotein"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04127">
        <property type="entry name" value="DFP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02441">
        <property type="entry name" value="Flavoprotein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102645">
        <property type="entry name" value="SSF102645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52507">
        <property type="entry name" value="SSF52507"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00521">
        <property type="entry name" value="coaBC_dfp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3 4" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="3 4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3 4" id="KW-0288">FMN</keyword>
    <keyword evidence="3 4 7" id="KW-0436">Ligase</keyword>
    <keyword evidence="2 3 4" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavoprotein" evidence="5">
        <location>
            <begin position="12"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="domain" description="DFP" evidence="6">
        <location>
            <begin position="193"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="region of interest" description="Phosphopantothenoylcysteine decarboxylase" evidence="3">
        <location>
            <begin position="1"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Phosphopantothenate--cysteine ligase" evidence="3">
        <location>
            <begin position="198"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="3">
        <location>
            <position position="166"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="286"/>
        </location>
        <ligand>
            <name>CTP</name>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="296"/>
        </location>
        <ligand>
            <name>CTP</name>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="314"/>
            <end position="317"/>
        </location>
        <ligand>
            <name>CTP</name>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="332"/>
        </location>
        <ligand>
            <name>CTP</name>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="346"/>
        </location>
        <ligand>
            <name>CTP</name>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="350"/>
        </location>
        <ligand>
            <name>CTP</name>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU364078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC94866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="402" mass="42776" checksum="9965411C8E68AEA9" modified="2018-07-18" version="1">MSDLASNPLKGKHILLGLTGGVACYKSAELCRSLIKHGATVQVVMTAGACQFITPVTMQALSGNPVYSDQWDARIANNMAHIELSRASDAILIAPCSTDFIAKLAHGHCDDLLSTLCVARPATLPLLIAPAMNVEMWQKPATQRNVAQLLEDGLQILGPAPGEQACGEVGMGRMLEPDQLIAELLAAFTPKSLAGKRVLITAGPTFEPIDPVRGITNLSSGKMGYAIAQAAFEAGATVSLISGPTALEMPYGCTRTSIQTAQQMRDAVFAQIEQQDIFISVAAVADWRVSNASDQKLKKNHAGDLPQLSFVQNPDILAEVAALAKPPYCVGFAAESENLIEYGTIKRLKKNVPLLVGNIAQNTFGQDQNELVLFDVNGHKSLPLADKTSLARQLITAIAARI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4S8</accession>
    <name>A0A2S9H4S8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">CDF: cation diffusion facilitator family transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_0138</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94943">
        <property type="protein sequence ID" value="PRC94943"/>
        <property type="gene ID" value="S2091_0138"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1510.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002524">
        <property type="entry name" value="Cation_efflux"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027469">
        <property type="entry name" value="Cation_efflux_TMD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01545">
        <property type="entry name" value="Cation_efflux"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161111">
        <property type="entry name" value="SSF161111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01297">
        <property type="entry name" value="CDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="30"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="62"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="99"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="126"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="198"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="230"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="157"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="170"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC94943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="333" mass="36059" checksum="988666FB7719DBA7" modified="2018-07-18" version="1">MNQFYEAPFGAGHDHVFLGEGHDSNGRKTWAVIALCSVMMIAEIVGGSLFGSLALVADGLHMSTHAGAMLIAALAYSYARKHVNNPRFVFGTGKMGDLAGFTSAIILAMIALLIGYEAISRFMSPVAISFTEAIPIAVLGLAVNIVSAWLLSGGDHGHHHGHSHHGHDHHDHHDHHEHDHHDHQHNEVDARDHNMRAAYVHVIADAAVSVLAIIGLLLARSFGWLWMDPLAGIIGALVIFSWSYTLIKDTGAILLDVNTNDAMGNKVKAVVKEAGDQLVDLHIWRLGPGHFGAVVSVLTNQAKREPAYYHALLKQHKGLSHITVEVQRTITAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4T5</accession>
    <name>A0A2S9H4T5_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">30S ribosomal protein S16</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rpsP</name>
        <name evidence="4" type="ORF">S2091_0189</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the bacterial ribosomal protein bS16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94994">
        <property type="protein sequence ID" value="PRC94994"/>
        <property type="gene ID" value="S2091_0189"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1320.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00385">
        <property type="entry name" value="Ribosomal_S16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000307">
        <property type="entry name" value="Ribosomal_S16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020592">
        <property type="entry name" value="Ribosomal_S16_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023803">
        <property type="entry name" value="Ribosomal_S16_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12919">
        <property type="entry name" value="PTHR12919"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00886">
        <property type="entry name" value="Ribosomal_S16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54565">
        <property type="entry name" value="SSF54565"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00002">
        <property type="entry name" value="S16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00732">
        <property type="entry name" value="RIBOSOMAL_S16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1 3 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC94994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="86" mass="9398" checksum="8FAF415A00FB2977" modified="2018-07-18" version="1">MVVIRLARGGAKKRPFFNIVATDSRNRRDGRFIERIGFYNPVASGAAETVRIAQDRLTHWTDHGAQLSPAVARLVALAAKQTPAAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5A4</accession>
    <name>A0A2S9H5A4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Chalcone-flavanone isomerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0364</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95169">
        <property type="protein sequence ID" value="PRC95169"/>
        <property type="gene ID" value="S2091_0364"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016872">
        <property type="term" value="F:intramolecular lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016087">
        <property type="entry name" value="Chalcone_isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016088">
        <property type="entry name" value="Chalcone_isomerase_3-sand"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036298">
        <property type="entry name" value="Chalcone_isomerase_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16036">
        <property type="entry name" value="Chalcone_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54626">
        <property type="entry name" value="SSF54626"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015424253" evidence="1">
        <location>
            <begin position="29"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="domain" description="Chalcone_isomerase" evidence="2">
        <location>
            <begin position="28"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC95169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="198" mass="22109" checksum="4DA9EA435010E232" modified="2018-07-18" version="1">MFTKFYGNFALSITLLLCPFIFSNHAFAVDVFGIKVPESVTISNQELVLNGAGIRTKFSTKYAVASLYLHEKKTTVDDVIALSGSKRLCLVLMKSSSSDYFAEGFITGIRNNATREEREKVFSSMAKFGQLFSIISDFQKGDIVTIDWIPNKGIVFAINDKQLGESINDQLFYSLFLKIWLGDHPLDSSLKRALLSGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5B6</accession>
    <name>A0A2S9H5B6_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_0369</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95174">
        <property type="protein sequence ID" value="PRC95174"/>
        <property type="gene ID" value="S2091_0369"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00088">
        <property type="entry name" value="HPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036061">
        <property type="entry name" value="CheW-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002545">
        <property type="entry name" value="CheW-lke_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036641">
        <property type="entry name" value="HPT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008207">
        <property type="entry name" value="Sig_transdc_His_kin_Hpt_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01584">
        <property type="entry name" value="CheW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01627">
        <property type="entry name" value="Hpt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00260">
        <property type="entry name" value="CheW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00073">
        <property type="entry name" value="HPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47226">
        <property type="entry name" value="SSF47226"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50341">
        <property type="entry name" value="SSF50341"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50894">
        <property type="entry name" value="HPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HPt" evidence="8">
        <location>
            <begin position="1"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="6">
        <location>
            <begin position="207"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="7">
        <location>
            <begin position="571"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="546"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="modified residue" description="Phosphohistidine" evidence="3">
        <location>
            <position position="45"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="4">
        <location>
            <position position="620"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC95174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="690" mass="74176" checksum="C86D13263BF0987D" modified="2018-07-18" version="1">MTKDPYRYFRIEASELLDQLAKNVLDLEKGSFGAELVMRLLRLAHTLKGAARVVKQSEIADLAHGLEDTLTPYRDGAQAFPREHVDSVLAALDAIAARLAQLPTPNNPDASASALVPDSAAIPAISAVRVVRADLIEVDMLLEGLGEIGNELGGVRRAIDSMERIRNLASQISVQHAIPQAKLNAASEEMCSLLATLERNMSAGILRIDRELREARDAAERLRLVPIASIFNTLERTARDAANITGKQVEFQASGGDVRIEGTILDTVQSALIQLVRNAVAHGIEMKALRSALGKPAIGRITLEVERRGYRAWFRCKDDGAGVDLDAVRRALYKKGISPIDTEKLDAGALMALLLKGGISTTSVVTEISGRGIGLDLVREAMQGLDGEVVARTESGHGTAIELSVPLSLAALDVLIVENVGYVAALPLDSVRCTLRIASEEIVHAPDGEFVLYEGKQIPFAPLYLGNPQKAVRSKSNFASRALTAVVVATGDALFAVAVERLCGMDTVVLRALPPSCPADPIVLGVYLDEEGNPRMVLNPDTLVAQRGSGNANTEGDSLPRSGSSQMSSAPILIIDDSLTTRMLECSILESAGFVVEMAACAEDGLDMARRGSYALFLVDVEMPGMDGFSFVKHTQADPLLREVPSILVTSCNSAEDRRRGKECGARAYIVKGEFDQVEFLERVTELVQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5F5</accession>
    <name>A0A2S9H5F5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Alpha/beta hydrolase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0366</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95171">
        <property type="protein sequence ID" value="PRC95171"/>
        <property type="gene ID" value="S2091_0366"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008536">
        <property type="entry name" value="DUF818"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05677">
        <property type="entry name" value="DUF818"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC95171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="317" mass="35179" checksum="22E8B4973ECCAC39" modified="2018-07-18" version="1">MYNFFRYKLELIVRSLIIGALIGLFTAPVAALASGNHHYDPVADDEFVADKAFPPKSKEVVFDSFGVSLYGQVYSTQGKGTHPTVLYARGFPDSTGSNDIARVLRRAGYNVMFFNYRGTYSMGGVFSEQHAYEDLQSALEFLRSDNSEKTMGIDPNNIILFGYSFGGPIVLRLAAENAKIRAVIHMDGTDLRAFKEMTPQDKAEWDEGLTSKLVPSATGKQITDEIMPHMDDWDPAHYSEGLAGKYVFLAWASKESSKQVDNVASLSDLFSKRSHVTATIFNTDHGFSDKHIALTRAILHWLKTIPQVKVASAEKSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5L0</accession>
    <name>A0A2S9H5L0_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 7">Transcriptional regulator MraZ</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">mraZ</name>
        <name evidence="10" type="ORF">S2091_0408</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="7">Forms oligomers.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
            <location evidence="7">Nucleoid</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the MraZ family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95213">
        <property type="protein sequence ID" value="PRC95213"/>
        <property type="gene ID" value="S2091_0408"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009295">
        <property type="term" value="C:nucleoid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd16321">
        <property type="entry name" value="MraZ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16320">
        <property type="entry name" value="MraZ_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1550.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01008">
        <property type="entry name" value="MraZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003444">
        <property type="entry name" value="MraZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035644">
        <property type="entry name" value="MraZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020603">
        <property type="entry name" value="MraZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035642">
        <property type="entry name" value="MraZ_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038619">
        <property type="entry name" value="MraZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007159">
        <property type="entry name" value="SpoVT-AbrB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037914">
        <property type="entry name" value="SpoVT-AbrB_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34701">
        <property type="entry name" value="PTHR34701"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02381">
        <property type="entry name" value="MraZ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89447">
        <property type="entry name" value="SSF89447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51740">
        <property type="entry name" value="SPOVT_ABRB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 7 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="6 7" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 7" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="SpoVT-AbrB" evidence="9">
        <location>
            <begin position="5"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="domain" description="SpoVT-AbrB" evidence="9">
        <location>
            <begin position="77"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51740"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC95213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="142" mass="15705" checksum="F34BDD3C02F82C07" modified="2018-07-18" version="1">MFQGASALTLDVKGRMTIPAKHRDALLMQCEGRVTLTRHPHGCILLFPRPVWDAHRTEIAAWPMSARAWQRIFLGNACDVDMDGAGRILVAPELRSAVELARDVMMLGMGTHFEVWDAKKLAESEAQAVATGMPDVLSNFSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5R5</accession>
    <name>A0A2S9H5R5_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Tol-Pal system protein TolB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">tolB</name>
        <name evidence="9" type="ORF">S2091_0468</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the TolB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95273">
        <property type="protein sequence ID" value="PRC95273"/>
        <property type="gene ID" value="S2091_0468"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017038">
        <property type="term" value="P:protein import"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00671">
        <property type="entry name" value="TolB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011659">
        <property type="entry name" value="PD40"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014167">
        <property type="entry name" value="Tol-Pal_TolB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007195">
        <property type="entry name" value="TolB_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07676">
        <property type="entry name" value="PD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04052">
        <property type="entry name" value="TolB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02800">
        <property type="entry name" value="propeller_TolB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3 7" id="KW-0132">Cell division</keyword>
    <keyword evidence="5 7" id="KW-0574">Periplasm</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015793028" description="Tol-Pal system protein TolB" evidence="7">
        <location>
            <begin position="30"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="domain" description="TolB_N" evidence="8">
        <location>
            <begin position="31"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC95273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="429" mass="46678" checksum="3A67144B2B4038C7" modified="2018-07-18" version="1" precursor="true">MNIAMTSQINKYVGRLFLLGCLLSFSAHAQLHVEISGVGATQIPVAIASFADEGIAPQLVSRIIKDDLIRSGYFKIIETSGALSETDSVNLPEWKAQGADALLVGSVHKTDDGRFDVRYKLYDTNKSSTLSAFAVAATPQYNRVSAHKIADDVYEKLTGIRGIFSTRIAYVTKSGPNYQLEIADSDGEGVQVAFRSKEPIMSPSWSPDGTKVAYVSFELRKPVVYVQNLMTGARTLVANYRGNNSAPVWSPDGSKVALALSRDGNTQVYTVNVDGSGLQRMTNTSGIDTEPQFSADGQFIYFTSDRSGGPQIYRMSAAGGEARRVTFTGSYNIAPRISPDGQTLAYISRRDGKFQLYALDLGNNQELRLTDTQDDDSPSFAPNSKYIMYATEVGQRGTLGVVSVDGRSKQRLTTQAGDVQNPTWGPFMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GS54</accession>
    <name>A0A2S9GS54_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Integrase core domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4740</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000062">
        <property type="protein sequence ID" value="PRC90552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90552">
        <property type="protein sequence ID" value="PRC90552"/>
        <property type="gene ID" value="S2091_4740"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13683">
        <property type="entry name" value="rve_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50994">
        <property type="entry name" value="INTEGRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase catalytic" evidence="1">
        <location>
            <begin position="135"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="382" mass="44246" checksum="97143BA11A5F4884" modified="2018-07-18" version="1">MTWNTANTMDLRLEFIHLALQEGANRRELCRRFGISPKTAYKWLERYAVQGEEGLQDRSRRPHHSPNHSSDHLEKLVVDLRHAHPCWGGRKIRQRLEDLGQNELPHAATVTHILRRHGLITPEASEQHTPWKRFEHEEPNALWQIDFKGNFETLHATCYPLTLLDDHSRFNLILAACARPNHDTVQAALTTTFERYGLPRRINADNGPPWGSPKQPTQSITKLTMWLIRLGIQVSHSQPAHPQTNGKIERFHRTLKAEVLNSNHFNDLPAAQIAFDRWRHIYNMERPHEGIQLRTPMTRYRPSPFTFPRILPPVEYLPGDVVIKVGWEGMFKFQNRPIKVSSALRNELIAIRPIVGMDGVFNVFYCRQKILKIDLRAATNSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSN5</accession>
    <name>A0A2S9GSN5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4608</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000038">
        <property type="protein sequence ID" value="PRC90715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90715">
        <property type="protein sequence ID" value="PRC90715"/>
        <property type="gene ID" value="S2091_4608"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015752300" evidence="1">
        <location>
            <begin position="19"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="274" mass="29811" checksum="381BEDB7C79B7D99" modified="2018-07-18" version="1">MKKLFFSLALVLSISATAQTAEQDRVNAECTVRSFFLQYASEAFGRSGAEPKFRQTQGAFDYVVEKTNNQDLKPKESRELIKSVVNFVYGSLRPDDVSLVSLVNMRDGYRAYCVSHPAEALGDVRVIDLDKALSANTAGSYHVQNKDGGETICSQGKCVSKPQSPPHYGISYSEARKVVVKLGWVPTPSVMSTILRKTGELSTSGTKFGTNEAYGNCLAGSPLCDKSMPELADCGIDGKCTAVWGKDGETFFYFIKGNVITGYGSTPANFINKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSW8</accession>
    <name>A0A2S9GSW8_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Flagellar biosynthetic protein FliQ</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">fliQ</name>
        <name evidence="10" type="ORF">S2091_4536</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Role in flagellar biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="9">Bacterial flagellum basal body</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the FliQ/MopD/SpaQ family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000036">
        <property type="protein sequence ID" value="PRC90788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90788">
        <property type="protein sequence ID" value="PRC90788"/>
        <property type="gene ID" value="S2091_4536"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009425">
        <property type="term" value="C:bacterial-type flagellum basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044780">
        <property type="term" value="P:bacterial-type flagellum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002191">
        <property type="entry name" value="Bac_export_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006305">
        <property type="entry name" value="FliQ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34040">
        <property type="entry name" value="PTHR34040"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01313">
        <property type="entry name" value="Bac_export_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004669">
        <property type="entry name" value="FliQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00952">
        <property type="entry name" value="TYPE3IMQPROT"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01402">
        <property type="entry name" value="fliQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0975">Bacterial flagellum</keyword>
    <keyword evidence="4 9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10" id="KW-0966">Cell projection</keyword>
    <keyword evidence="10" id="KW-0969">Cilium</keyword>
    <keyword evidence="10" id="KW-0282">Flagellum</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="16"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="51"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU364090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC90788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="89" mass="9856" checksum="250F4B46BA0E0018" modified="2018-07-18" version="1">MTPEQVMTIGRHAMQITLMIAIPMLLVALTIGLMVSIFQAATQINEMTLSFIPKLIGVFLVLDLAGPWMLTILTDYMRELFMGIPGMVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GT99</accession>
    <name>A0A2S9GT99_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">HprK-related kinase A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4345</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000032">
        <property type="protein sequence ID" value="PRC90944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90944">
        <property type="protein sequence ID" value="PRC90944"/>
        <property type="gene ID" value="S2091_4345"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027600">
        <property type="entry name" value="HprK-rel_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04352">
        <property type="entry name" value="HprK_rel_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC90944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="303" mass="33707" checksum="5FDDDD42DE57D543" modified="2018-07-18" version="1">MKLSSLTPSELIRQLRQGLFLQTGAFVVHIKTRIPAVAHGLGLLYADYSLASNEFADFHVTLAPPRNLRRWLRSQVLFQFEGKLPFKPLPYSQAFPMLEWGLNWCVSNHAHTYLMIHAAVVEKGGRAAILPAPPGSGKSTLCAALINRGWRLLSDELTLIRLNDGLIESFPRPVSLKNGSIEVIKRYVPSAIFSPVVKDTIKGTVAHMKPSTDSVQRGQEPARAAWIIFPKFTVGAETRLEEIPSARAFMRVADNSFNYGLLGQQGFQALAQLIDHSQAFDFSYSELDEAMQVFDNLTLTKQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTA6</accession>
    <name>A0A2S9GTA6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4346</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000032">
        <property type="protein sequence ID" value="PRC90945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90945">
        <property type="protein sequence ID" value="PRC90945"/>
        <property type="gene ID" value="S2091_4346"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039498">
        <property type="entry name" value="NTP_transf_5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14907">
        <property type="entry name" value="NTP_transf_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC90945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="360" mass="40835" checksum="46B14E34FFA0922B" modified="2018-07-18" version="1">MRPNGLILAALRDPASLPDWNLHEWDLLLRQLRHANLTASLHAQLLALGLLSRIPAQPRRHLDWSAKLASRHTQSVLWEVEFIRQAMSEAGVPLILLKGAAYVMAALPHSRGRIFSDIDIIVPKENLDLVESTLMLYGWNATHHDGYDQRYYRTWMHELPPMQHLTRATAIDVHHAILPVTARLHPDSTKLLAAAVPANGDLTTLVFAPIDMVLHSAVHLFHDGEYDQGLRDLVDIHSLLVHFSAEPGFWTSLTTRAQELELVRPLFYALRYAARLLHTPIPLQVMQAADSGRPNSVLLALMDSLFERALMPKHASCNDRYTGVARFALYLRANWLRMPLLLLTRHLLHKAILSPRKKEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTM1</accession>
    <name>A0A2S9GTM1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4248</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000030">
        <property type="protein sequence ID" value="PRC91060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91060">
        <property type="protein sequence ID" value="PRC91060"/>
        <property type="gene ID" value="S2091_4248"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="131" mass="14769" checksum="5F2703A183CCE27B" modified="2018-07-18" version="1">MISNNPSSLSISKHNDAIHPSRLFTQREIAVTHAANALPLTIKMSLVDRIKKQLMRGFKKNEITLISPKNYEIQIMPTPKLTSGAPRLVRNDRLFFSVAVISLMNPTISKRYWLANKVPRDKLTNTSSNLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTT5</accession>
    <name>A0A2S9GTT5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_4135</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000028">
        <property type="protein sequence ID" value="PRC91134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="SMR" id="A0A2S9GTT5"/>
    <dbReference type="EnsemblBacteria" id="PRC91134">
        <property type="protein sequence ID" value="PRC91134"/>
        <property type="gene ID" value="S2091_4135"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-binding" evidence="1">
        <location>
            <begin position="16"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding_C" evidence="2">
        <location>
            <begin position="433"/>
            <end position="508"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="527" mass="59385" checksum="4A3616672CB06C0F" modified="2018-07-18" version="1">MKMNFCRVMRLMALRFGEQEAIVNVERQRRYNYDEYHRLTNRIANALRTELQVGCGDKFMLILENDNLSLMLFPVVFKQEGTVVMTNLRDSIEEHERQLDLVQPKVVFIETRLLETYSALLHSKGCTVVAMDEIPEPQKYPEVRAFWDLVEAASELDNDVELDTDEHIFMLRFTGGTTGKGKCAMYSIDNILASRDGGFINFDLNFTDATRLVHVTPLSHGTLITFFPTFFAGGTNLTMNQLNLDHWREVVETERVTHSFLVPTVLYRLLELQRALPRDFSSLKTLIYGAAPISPVKLDELVQCFGQIFAQGYAATEAAMFISILDKAEHRSNDDAAIKHLSSAGRATPGVEIFITDKQGKPLPFGETGEIRIRCKAIIKGYYDNPEATAAEFEDGAWKSGDLGYIDANGYIYIVDRVKDMIISGGFNIYAIEVEAALQAHPAVLMAAVVGIPHPEWGESLHAEVVLRQGVSVAAEELIAHSKNRLGAYKAPKTLIFVEELPLSVVGKVLRRKVKEKYWQHMDRKIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GU03</accession>
    <name>A0A2S9GU03_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 10">L-aspartate oxidase</fullName>
            <ecNumber evidence="4 10">1.4.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">S2091_4083</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the oxidation of L-aspartate to iminoaspartate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-aspartate + O2 = H2O2 + iminosuccinate</text>
            <dbReference type="Rhea" id="RHEA:25876"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:77875"/>
            <dbReference type="EC" id="1.4.3.16"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="9">
            <dbReference type="Rhea" id="RHEA:25877"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 10">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 10">Cofactor biosynthesis; NAD(+) biosynthesis; iminoaspartate from L-aspartate (oxidase route): step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.4.3.16" evidence="4 10"/>
    <dbReference type="EMBL" id="PUGF01000027">
        <property type="protein sequence ID" value="PRC91188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91188">
        <property type="protein sequence ID" value="PRC91188"/>
        <property type="gene ID" value="S2091_4083"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00253">
        <property type="reaction ID" value="UER00326"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008734">
        <property type="term" value="F:L-aspartate oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044318">
        <property type="term" value="F:L-aspartate:fumarate oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009435">
        <property type="term" value="P:NAD biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.700.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003953">
        <property type="entry name" value="FAD-binding_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037099">
        <property type="entry name" value="Fum_R/Succ_DH_flav-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015939">
        <property type="entry name" value="Fum_Rdtase/Succ_DH_flav-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005288">
        <property type="entry name" value="NadB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027477">
        <property type="entry name" value="Succ_DH/fumarate_Rdtase_cat_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42716">
        <property type="entry name" value="PTHR42716"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00890">
        <property type="entry name" value="FAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02910">
        <property type="entry name" value="Succ_DH_flav_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46977">
        <property type="entry name" value="SSF46977"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56425">
        <property type="entry name" value="SSF56425"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00551">
        <property type="entry name" value="nadB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="10" id="KW-0274">FAD</keyword>
    <keyword evidence="5 10" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6 10" id="KW-0662">Pyridine nucleotide biosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD_binding_2" evidence="12">
        <location>
            <begin position="4"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="domain" description="Succ_DH_flav_C" evidence="13">
        <location>
            <begin position="444"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="456"/>
            <end position="483"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00029281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU362049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="PRC91188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="551" mass="60581" checksum="358FC15CFD8B885C" modified="2018-07-18" version="1">MNYDVAIIGSGLAGFSVALHLAENHKVAIFSKRSLLDGSSSWAQGGIAAVLDSGDSVEQHLSDTIIAGGGLCDEAATRYILENGRSAIDWLIAQGVPFTPDADAELGYHLTREGGHSQRRIIHAADATGHAVQVTLEQQIRNHPNITLFEHHYAIDLITSDKLADPASANVNPTPARCLGLYVQDVQTGKVHTVTAQHTVLATGGAGKVYLYTTNPDTATGDGIAMAWRAGCRIANMEFIQFHPTCLYHPYAKSFLISEAVRGEGGLLKLPAEAGTSAGKRFMPAHDERAELAPRDVVARAIDFEMKKRGLDHVDLDITHQPPEFLQEHFPTIYARCLELGIDITKQPIPVVPAAHYTCGGIVTDMTGRTDLAGLYAVGETSYTGLHGANRLASNSLLECLVIGKAVAEQIADQEILRSPDLPSWDESRVTDADEEVVIAHNWDELRRFMWNYVGIVRTTKRLERAQHRIRLLKEEIDEYYANFRITNHLLELRNLVDVASLIVNSALSRRESRGLHFSRDFPDTLPKAIPTVLAPQLREKTRNGKIRHGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GU32</accession>
    <name>A0A2S9GU32_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4113</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000027">
        <property type="protein sequence ID" value="PRC91218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91218">
        <property type="protein sequence ID" value="PRC91218"/>
        <property type="gene ID" value="S2091_4113"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009962">
        <property type="entry name" value="DUF1488"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036692">
        <property type="entry name" value="Shew3726-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07369">
        <property type="entry name" value="DUF1488"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160272">
        <property type="entry name" value="SSF160272"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="88" mass="9988" checksum="FE2602392A5E9054" modified="2018-07-18" version="1">MEISFPNLVMPKVTAMGTISFQTLVDGEYIWCEISCEALRDHFGAHSMDGNDLLYSFHMSKEEILQTARNYLELNGGRPVLLMAVNFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GU42</accession>
    <name>A0A2S9GU42_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Penicillin amidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_4040</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S45 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000026">
        <property type="protein sequence ID" value="PRC91255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91255">
        <property type="protein sequence ID" value="PRC91255"/>
        <property type="gene ID" value="S2091_4040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016811">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017000">
        <property type="term" value="P:antibiotic biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1400.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.439.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014395">
        <property type="entry name" value="Pen/GL7ACA/AHL_acylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043147">
        <property type="entry name" value="Penicillin_amidase_A-knob"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023343">
        <property type="entry name" value="Penicillin_amidase_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043146">
        <property type="entry name" value="Penicillin_amidase_N_B-knob"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002692">
        <property type="entry name" value="S45"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34218">
        <property type="entry name" value="PTHR34218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01804">
        <property type="entry name" value="Penicil_amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001227">
        <property type="entry name" value="Pen_acylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0865">Zymogen</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015442073" evidence="5">
        <location>
            <begin position="26"/>
            <end position="742"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4">
        <location>
            <position position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR001227-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC91255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="742" mass="83895" checksum="CB99446B4F046B7B" modified="2018-07-18" version="1">MNKLLKFSVPFIAAICMAVTSYSAAASPDQSELKRWKTQAQHVQIIRDNWGIPHVYGNTDADAVFGVLYAQAEDNFNRIELNYINALGRLAEVEGESALYRDLRMKLFINPADMQAKYTDSPAWLKKLMNSFADGLNFYLYTHPQVHPKLLTHFEPWMALCFSEGSIGGDIETIDLKQLEQFYSGHPTLMAQTQPEQEINKVDPEPGGSNGFAIAPSLTVSKHALLLINPHTSFYFRPEVHMISKQGLNAYGAVTWGQFFIYQGFNSRLGWMHTSGGANVINEYLETVTRNNDGDGYVYRYGAELRPLKATTIQLRYKTDSQMAEKNVTVYYSQHGPIVRKIGDQWVAVRLMQEPVKSLMQSYSRTRAKNYADFYRVMELRTNSSNNTVYADADGNIAYFHGNFVPKRDTRFDWSQPVDGSNPDTEWQGLHEVKETITLLNPSNGWIQNTNNWPFTVAGANSPRQQDYPAYMWVNPENARGIHALRVLKNHSNFTLDSLISTAYDNYLPAFEVLMPALLKAWDDTAEANPLKLQLKDQIDLLRNWDLRYANESVPTALAIYWGQEMMKKIDARAKEKKIGKSSWAVFDFIAANTTAQEKLESLFFASARLEQDFGSWKTPWGEINRFQHISGAIEQAYDDTKPSLPIPFTASVWGSLAAFGTTSPSKTRRIYGDRGNSFVAVVEFGPRIRAKSVLAGGESGDPASPHFNDQAEMYSKGGFKDVLFYPDDVKKHSERSYHPGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GU86</accession>
    <name>A0A2S9GU86_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Efflux transporter, RND family, MFP subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_4046</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000026">
        <property type="protein sequence ID" value="PRC91261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91261">
        <property type="protein sequence ID" value="PRC91261"/>
        <property type="gene ID" value="S2091_4046"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006143">
        <property type="entry name" value="RND_pump_MFP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01730">
        <property type="entry name" value="RND_mfp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015541410" evidence="2">
        <location>
            <begin position="23"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="domain" description="HlyD_D23" evidence="3">
        <location>
            <begin position="65"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC91261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="393" mass="42568" checksum="22E85896B969C498" modified="2018-07-18" version="1">MHFTFRQQLLVVLFTASSLLLAGCSNEQPRAMPSIPEVTIQTVVPKEVPITMELVGETAGYRDIEVRARVGGILLKRTYVEGQPVKQGQVLFQIDPAPYQVMLEQAKGAQAQQQAALDKATADRDRIAPLYRENAISKMDFDNASSAYNVALAAKQSADAKVKEAQLNLDYTHVTAPISGMTSKQVQSEGSLIRVDAAEPLTTISQFDPLYVNFSISEQSKLDNKRNLREGTIVAPPEGQKTVKIRLSDGHYYSQAGKIDFHDNRVDPKTGTIRTRAMFANPNGDLLPGQFVRVLVDIGIRNTTITVPEQAIMPSQADNLILTVDGSNKVVSNSVQLGQQIGGEVVIESGLKAGDRVIINGGMKARAGDAVTPVADQTTAQIPAQSTTQLNTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUH1</accession>
    <name>A0A2S9GUH1_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Protein adenylyltransferase SelO</fullName>
            <ecNumber evidence="9">2.7.7.n1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">selO</name>
        <name evidence="10" type="ORF">S2091_3977</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ATP + L-seryl-[protein] = 3-O-(5'-adenylyl)-L-seryl-[protein] + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:58120"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:15073"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:142516"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ATP + L-threonyl-[protein] = 3-O-(5'-adenylyl)-L-threonyl-[protein] + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:54292"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:13847"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:138113"/>
            <dbReference type="EC" id="2.7.7.n1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ATP + L-tyrosyl-[protein] = diphosphate + O-(5'-adenylyl)-L-tyrosyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:54288"/>
            <dbReference type="Rhea" id="RHEA-COMP:10136"/>
            <dbReference type="Rhea" id="RHEA-COMP:13846"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:46858"/>
            <dbReference type="ChEBI" id="CHEBI:83624"/>
            <dbReference type="EC" id="2.7.7.n1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the SELO family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.n1" evidence="9"/>
    <dbReference type="EMBL" id="PUGF01000025">
        <property type="protein sequence ID" value="PRC91306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91306">
        <property type="protein sequence ID" value="PRC91306"/>
        <property type="gene ID" value="S2091_3977"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00692">
        <property type="entry name" value="SelO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003846">
        <property type="entry name" value="SelO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32057">
        <property type="entry name" value="PTHR32057"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02696">
        <property type="entry name" value="SelO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 9" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0808">Transferase</keyword>
    <feature type="active site" description="Proton acceptor" evidence="9">
        <location>
            <position position="248"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="91"/>
            <end position="94"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="109"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="121"/>
            <end position="122"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="172"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="179"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="249"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="258"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC91306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="485" mass="54041" checksum="C1DFB43BA1CFBE27" modified="2018-07-18" version="1">MSTLFNELVFTDSFGALGTEFSTPQPPTPLPEPYLIATSPSSLALCGISPEQAKTSEFIHLFTGNQLPASSQPRAAVYSGHQFGQWAGQLGDGRAILLGELAGLEVQLKGAGATPYSRMGDGRAVLRSSIREFLCSEAMVGLGVPTTRALCITGSPMLVMREQPESTAVVTRIAASFVRFGSFEHWFYRDDVTSLKNLADFVIQRYYSELSGLENPYAALLRKVTKRTAHLMAHWQTVGFMHGVMNTDNMSILGLTLDYGPFGFMEAFNPQHICNHSDNQGRYSYAMQPQIGEWNCYALGQALLPLIGSVDETKAALADFGLEYQSKLAALWQAKLGLTCSMEEDDALISAMLSMMKINQLDFTIFFRRLSDCYLNDASMDDQLRDLCVDRDALDQWLSQYRLRLTKEASVDAVRQQVMRRHNPKFILRNYLAQQAIEAAQRNDFSEIEKLRQILANPFDEQPEHELYAALPPDWGRALSVSCSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GV22</accession>
    <name>A0A2S9GV22_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Thioredoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3784</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000022">
        <property type="protein sequence ID" value="PRC91506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91506">
        <property type="protein sequence ID" value="PRC91506"/>
        <property type="gene ID" value="S2091_3784"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="1">
        <location>
            <begin position="1"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="141" mass="16149" checksum="6AD066167E6B9B72" modified="2018-07-18" version="1">MPYLDLNHTSAAALQQHLTKYQTVVACLCAAWCDVCKDYRPKFEALAEQHPELLFLWIDIEDQASLVGDLDIENFPTLLIQQNDVVSFYGTMQPDTSQLKRIIQSQARQSPEQLQTQANFDGQQRLWQTEANLRLRLALAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GV63</accession>
    <name>A0A2S9GV63_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3719</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000021">
        <property type="protein sequence ID" value="PRC91603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91603">
        <property type="protein sequence ID" value="PRC91603"/>
        <property type="gene ID" value="S2091_3719"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="38" mass="4128" checksum="0FF1C71CF6C6E847" modified="2018-07-18" version="1">MKSPDLSEFSSFFAAHSIAHHASICSNQALTDHSVPKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GV91</accession>
    <name>A0A2S9GV91_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3734</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000021">
        <property type="protein sequence ID" value="PRC91618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91618">
        <property type="protein sequence ID" value="PRC91618"/>
        <property type="gene ID" value="S2091_3734"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007436">
        <property type="entry name" value="DUF485"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04341">
        <property type="entry name" value="DUF485"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="24"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="58"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="102" mass="11484" checksum="2B7A232DB80D4073" modified="2018-07-18" version="1">MEDQLVKKILANPNYQKLVKTRSAYGWLFTALVMIVYYGFILLIAFDKELLSAKFGDGVMTIGMPVGLFVLVFTVVITGIYVRRANKEFDDLTAKIKAEVLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVB8</accession>
    <name>A0A2S9GVB8_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Glycerol-3-phosphate dehydrogenase</fullName>
            <ecNumber evidence="6">1.1.5.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_3589</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>a quinone + sn-glycerol 3-phosphate = a quinol + dihydroxyacetone phosphate</text>
            <dbReference type="Rhea" id="RHEA:18977"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:57597"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="EC" id="1.1.5.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.5.3" evidence="6"/>
    <dbReference type="EMBL" id="PUGF01000020">
        <property type="protein sequence ID" value="PRC91651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91651">
        <property type="protein sequence ID" value="PRC91651"/>
        <property type="gene ID" value="S2091_3589"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009331">
        <property type="term" value="C:glycerol-3-phosphate dehydrogenase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052591">
        <property type="term" value="F:sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006072">
        <property type="term" value="P:glycerol-3-phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.870">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031656">
        <property type="entry name" value="DAO_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038299">
        <property type="entry name" value="DAO_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000447">
        <property type="entry name" value="G3P_DH_FAD-dep"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11985">
        <property type="entry name" value="PTHR11985"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16901">
        <property type="entry name" value="DAO_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01001">
        <property type="entry name" value="FADG3PDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00977">
        <property type="entry name" value="FAD_G3PDH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3 6" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DAO" evidence="7">
        <location>
            <begin position="6"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="domain" description="DAO_C" evidence="8">
        <location>
            <begin position="388"/>
            <end position="496"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF16901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC91651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="513" mass="57302" checksum="EDF0391B92626D6F" modified="2018-07-18" version="1">MNKQVDMLVVGGGINGVGIARDAAGRGLSVLLCEKDDLASHTSSASTKLIHGGLRYLEYYEFGLVRKALQEREVLLRAAPHIISPLRFVMPHVAHLRPAWMIRIGLFFYDHLSKRNILPGSRGINLKKHPAGAPLHDNFTKGFVYSDAWVDDARLVVLNAKDAQERGATILTRTKLVSAKPDAQGWHAELLNAQQKTIHIHARCIVNATGPWASALLNNAIHSDALTPRNEVRLVKGSHIVTKKLFEHDHAYIFQNPDKRIIFAIPYLDQFTLIGTTDLEYKEDPNHVTITEDEITYLCESANTYFKQSIHPSDVVWSYSGVRPLLEQEDAANPSAVTRDYQLELDTPHKLAVVLSVFGGKITTFRRLAEEAVNLLTPSLGIQQPDWTATATLPGGDIPHADFPTFCSEFQQQHAWLPVQLAKRYAHNYGTRATQLLNGAVNMAGLGEQLSPGLFELEAHYLVKHEWAQQVDDILWRRTKLGLAATPESIQRLQQWLDHAVTTIHTEAETHGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVC2</accession>
    <name>A0A2S9GVC2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Haloacid dehalogenase-like hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3607</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000020">
        <property type="protein sequence ID" value="PRC91669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91669">
        <property type="protein sequence ID" value="PRC91669"/>
        <property type="gene ID" value="S2091_3607"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041492">
        <property type="entry name" value="HAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13419">
        <property type="entry name" value="HAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="231" mass="26550" checksum="1C53D231A67F93F2" modified="2018-07-18" version="1">MYKSNKRLIILDADGTTIDAFSAITSTFSQHGMDLGNEDNFQKRHNLFKYMGGFKEFPRNIKKQISHRKRLIATLTDVYRDEAQLYPGIAELIQRLISAPNVVVGIVTRNITNQPIETLGKLFFRHGIDVAQLDFLHHIPVKQNKISAFKEIREHYDINPALSYICGDEHKDYHAALASGMHPFMVSYGFEDHQRLTEKFNIPEELIARSPRELCARVCHTLQLTELIDPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVC7</accession>
    <name>A0A2S9GVC7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">PBP superfamily domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3598</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000020">
        <property type="protein sequence ID" value="PRC91660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91660">
        <property type="protein sequence ID" value="PRC91660"/>
        <property type="gene ID" value="S2091_3598"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024370">
        <property type="entry name" value="PBP_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12727">
        <property type="entry name" value="PBP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="1">
        <location>
            <begin position="25"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="domain" description="PBP_domain" evidence="2">
        <location>
            <begin position="142"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="360" mass="39468" checksum="48941CF64E9B4986" modified="2018-07-18" version="1">MYKVKITPHWEISSDSEAALDTSALLSLLASIQTTGSIAQAAQEVGLSYRYAWGILRDGEKLFGEVLMSKSRGRGTTLTPLAEKLIWADRRVAARLSPTLESLASELESELNKNSLEKSKAIRLHASHGFAVASLLTIFNKEKLAVETIYRNSTDAVAALSRKECDLAGFHVPLGEFEAPAIAQYSQWLNPKTHCLIHLAVRNQGLFIAPGNPKGIRGIADLNKHNINFVNRQKGSGTRMLLELMLANLDISPNDINGFENTEFTHSAVAAFIASGMAEVGFGVQTAAQRFGLDFIPLVRERYFFALPLAALDDPIIQHVIAILQSTGFRDEIQQLAGYDSLDTGKILSINEAFPYIKRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVE3</accession>
    <name>A0A2S9GVE3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Bacterial extracellular solute-binding protein, family 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3606</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000020">
        <property type="protein sequence ID" value="PRC91668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91668">
        <property type="protein sequence ID" value="PRC91668"/>
        <property type="gene ID" value="S2091_3606"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001638">
        <property type="entry name" value="Solute-binding_3/MltF_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00497">
        <property type="entry name" value="SBP_bac_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="PBPb" evidence="2">
        <location>
            <begin position="27"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="242" mass="28066" checksum="37A9D4F248BBDC05" modified="2018-07-18" version="1">MWRRSLIVVIYFVPLIASATTIDFYFETYPPWLMLNPPSTAMTGIAVEEVTEMMRRAKWEFTIEHTSQASSYEHVRNNITGCSFPVFRHEAKATLYTWVMPMAEENWVAYGRSDDHRNPKNLAELKPYVIGSYLKAGSGTELAARGFNIEFSARDEDNPNLLINKRLDYWITTEIHGDYMIQQLGLQKKITKQFVVFRRGLNLMCNLNMDKKLVETMSAIFKEMELDGTNEKILNKYKLSPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVI4</accession>
    <name>A0A2S9GVI4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Threonine dehydrogenase and related Zn-dependent dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_3494</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000019">
        <property type="protein sequence ID" value="PRC91739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91739">
        <property type="protein sequence ID" value="PRC91739"/>
        <property type="gene ID" value="S2091_3494"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="PKS_ER" evidence="3">
        <location>
            <begin position="10"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC91739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="345" mass="36792" checksum="3D07B25F25EF1DEB" modified="2018-07-18" version="1">MKALVYHGKGEKSLDDCPKPEILAPTDAIVSVTRTTICGTDLHILKGDVPTCQPGRILGHEGVGIVEQIGAAVTAFKPGDHVLISCISACGKCSYCRKQMYSHCVTGGWILGNSIDGTQAEFVRIPYADTSLYPIPAGADEEALVMLSDILPTGFECGVLNGKVQPGNTVAIVGSGPIGLAALLTAQFYSPAEIIMIDLDDNRLEVAKRFGATSIINSKDGQAVETIMKLTGGRGVDTAIEAVGIPATFEMCEKIIAPGGTIANIGVHGTKVDLHLETLWDRNLTITTRLVDTISTPMLLNVLQSKKLDAKSLITHRFKLNDVLEAYETFEHAADTHALKVIIEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVT7</accession>
    <name>A0A2S9GVT7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Isochorismatase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3393</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000018">
        <property type="protein sequence ID" value="PRC91837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91837">
        <property type="protein sequence ID" value="PRC91837"/>
        <property type="gene ID" value="S2091_3393"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.850">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000868">
        <property type="entry name" value="Isochorismatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036380">
        <property type="entry name" value="Isochorismatase-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00857">
        <property type="entry name" value="Isochorismatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52499">
        <property type="entry name" value="SSF52499"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Isochorismatase" evidence="1">
        <location>
            <begin position="3"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="174" mass="19554" checksum="1BD3A351A7BCAF08" modified="2018-07-18" version="1">MKTALIVIDFQNSIFNAPPAYEVHQVMERISAVIQKARKAGVAVIYVQHQEDSTGWQAGTPDWEFPSAIAPQADDYLVHKSVASAFVDTNLLAHLTEQEIQRVYICGYATEFCIDTNVRQCASLKLNTVVISDAHTTRDRPHLSAPKIIEHHNWVWSEFGGIQLCQTSLVEFDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVU4</accession>
    <name>A0A2S9GVU4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltransferase domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3399</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000018">
        <property type="protein sequence ID" value="PRC91843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91843">
        <property type="protein sequence ID" value="PRC91843"/>
        <property type="gene ID" value="S2091_3399"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_25" evidence="1">
        <location>
            <begin position="46"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="211" mass="23458" checksum="09BAAEC432E63862" modified="2018-07-18" version="1">MDNCQISVNTFNTLADNYAQKYFALSTYDGCYRIFCSQLSKKGGSVLDVACGPGNVANFLVRERPDLEVTGIDLAPRMIQLAKTLVPTANFLAHDCRHLSTLSRVYDGIVYAFGLNYLNQQDTEQVFDSIPNVLALNGTFYLSVMLGSAEQSGIQTSSSGNQVYIYYRPRQEIERLVRNAGLELIYLEEFSSPSNAPTATIDLVLIARRIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GW17</accession>
    <name>A0A2S9GW17_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Outer membrane protein assembly factor BamB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">bamB</name>
        <name evidence="7" type="ORF">S2091_3468</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Part of the Bam complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the BamB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000018">
        <property type="protein sequence ID" value="PRC91912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91912">
        <property type="protein sequence ID" value="PRC91912"/>
        <property type="gene ID" value="S2091_3468"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043165">
        <property type="term" value="P:Gram-negative-bacterium-type cell outer membrane assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051205">
        <property type="term" value="P:protein insertion into membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00923">
        <property type="entry name" value="OM_assembly_BamB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017687">
        <property type="entry name" value="BamB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018391">
        <property type="entry name" value="PQQ_beta_propeller_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002372">
        <property type="entry name" value="PQQ_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_supfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13360">
        <property type="entry name" value="PQQ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00564">
        <property type="entry name" value="PQQ"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="SSF50998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03300">
        <property type="entry name" value="assembly_YfgL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="5 7" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="2 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0564">Palmitate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015792081" description="Outer membrane protein assembly factor BamB" evidence="6">
        <location>
            <begin position="23"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC91912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="376" mass="39538" checksum="B6C75D67C48DB83D" modified="2018-07-18" version="1" precursor="true">MRRAIKLMCVSAAVCLTACSMFKEPKNPPAALVEFKSSMSIKAVWSANVGASGDYVFAPVAVQNSIFTAAANGNIFRFDNATGREIWKVEAELPLTAGVGADSSTLAVVGEKGVLLAYDLDGKLRWKAQASSEVLSTPVVGGGVVVVRSIDNHIAAYDSVTGKRRWVVERTLPPLILRSAAGMAIADNSVYVGLPGGKLIAITLISGSVRWEAAVGEPRGATELERVADVSGVPVVLGSDVCASAYQGKVSCFDVKTGVMRWGKALSTDMGVSVDERFVFAVDDKGTVNAFSRSAGLSEWKNDKLAYRRLSTPISFGQAVAVADMSGYVHFLSREDGSFLARTSTDGSAIVATPIVAGANVVFQTKVGEIVAFAID</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GW38</accession>
    <name>A0A2S9GW38_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Bacterial extracellular solute-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_3432</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000018">
        <property type="protein sequence ID" value="PRC91876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91876">
        <property type="protein sequence ID" value="PRC91876"/>
        <property type="gene ID" value="S2091_3432"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006059">
        <property type="entry name" value="SBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001638">
        <property type="entry name" value="Solute-binding_3/MltF_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01547">
        <property type="entry name" value="SBP_bac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00497">
        <property type="entry name" value="SBP_bac_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015586416" evidence="2">
        <location>
            <begin position="23"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="domain" description="PBPb" evidence="3">
        <location>
            <begin position="40"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC91876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="683" mass="76016" checksum="3AC75591F0561AD5" modified="2018-07-18" version="1">MRNFLILAFLIFNATSFYNAHAVEIKGNAKEVVLSAVEQPPYVGQNLPSNGYAGQVAIEAFKRIGYTVKIEFFPLARANQMAATGQVDGQLAIYSNKASENTFLLSDPFPGGHLVLLKKIGSKITNTAGESDISTLLKSLSSYRIGAVNRVTISPEFDHADFLKKYTVNNDIENLDMLMVDQLDLAVMDKLTAGDLMAEQRPQYIRQLEVFSSLATNSFHVGFSRTSAQSKKLKEDFDRGLKMLDADGSLARIMYVHGLSMHLPSVKGKTKLTIGTLNVSSMLILQKLSVQYQKKHPDISFDWRILDEKILRLRQLTDLAVSDGQYDIMTIGAYETPIWAKNNWILPLKNLSPQYDLEDVIKPVRNMLSFQENLYGLPFYAESSMTFYRKDLVANAGLTMPEAPTYDDIKKIAAAIHAPDKQIYGICLRGDPGWGANMALITTMVNSAGGRWFDENWDPMIDTPEWKLALQTYKDLLTQYGPPNPEEQDYAKNLTLFQGGHCGIWIDATVFAGALLDAKQSKVAAKVGFTRTPVFSTANGSQWLWTWALAIPTSSKAPAEALKFIEWATSKEYIELVAKREGWLNVPPGTRASTYKDPRYRAVASFADVVFKAINEANPNNASLKPRPYIGIQFVEIPEFVSIGDNIGYLASSVLAQKISVDTALKIGQKNTTVQMRKSHIIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GW39</accession>
    <name>A0A2S9GW39_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Beta-lactamase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3263</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000017">
        <property type="protein sequence ID" value="PRC91921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91921">
        <property type="protein sequence ID" value="PRC91921"/>
        <property type="gene ID" value="S2091_3263"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta-lactamase" evidence="1">
        <location>
            <begin position="42"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="566" mass="62830" checksum="389426D9BA11BB72" modified="2018-07-18" version="1">MKRREFLRLSIQTAAAATTSNFIINEAQAITKSSYAAIFPLLDQFIQQYLKDMNAPGLTLTLVDASGIQRVCTFGVEDSVKRSAIKPNKLFHIGSITKSFLGLCLMQLHDEGKLDLDRPIAEYLPWVRFDSTTRSISTHDLLTHSAALPDGELFPTDPSFRHHATAAPGTFFHYCNMGYDALGLLLETLDQRPLAESFRVRILNPVGMKSTEPIITLDMANRVVNSYMVELNDRPYPRAGRLVAAPPIAVTTASGCIASNAVDMGAYLQMLINRGQVPTGRLVSEAGFKLFSTPHAEADEFGKGAKYGYGITVDTLDGHTRLRHTGGMVSFASALEVDLDAGLGVFVSVNSMQGYRPRPVAEYALRLMRASREGKPLPKIPLQKPSDYVDKASDYEGRFSGADGRILEITSVGDRLYLIHRGTQVTLEPTIGAENSFTVLHPEFAKFAVHFKRDGDKKEGKFAEVGWGNDWYVSADYTGAREFSVPSEWHSYVGHYRNDSDWIGSMHVVLRAGILWLDGVIPLEPTPDHRFFLRDEMDSPEWISFSEMVNGHPMRMKLSGKDLARV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWE2</accession>
    <name>A0A2S9GWE2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Peptidase family S41</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3165</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000016">
        <property type="protein sequence ID" value="PRC92030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92030">
        <property type="protein sequence ID" value="PRC92030"/>
        <property type="gene ID" value="S2091_3165"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015536657" evidence="1">
        <location>
            <begin position="26"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="138" mass="14894" checksum="FA764FAE786C2451" modified="2018-07-18" version="1">MNPSSISNFKLFFLAASLLSPFASAQVAESTMPTQQTAPLNLDTDKVSKEISQEQPVYLIKKDTLSAGENAFTNTFTQAEKKVKVSGEVEIGVGTSQRVTKVTNPNGSYCVYSPTVARTDGVDEIQNGLQTQVRSCPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWG5</accession>
    <name>A0A2S9GWG5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3197</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000016">
        <property type="protein sequence ID" value="PRC92062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92062">
        <property type="protein sequence ID" value="PRC92062"/>
        <property type="gene ID" value="S2091_3197"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="46" mass="5305" checksum="5D187EE43B9E8C26" modified="2018-07-18" version="1">MHLFCRSTILLYIKLPHFVLGRVESNLVSYGSTQPNIPIHHAKLFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWJ2</accession>
    <name>A0A2S9GWJ2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alginate lyase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3219</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000016">
        <property type="protein sequence ID" value="PRC92084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92084">
        <property type="protein sequence ID" value="PRC92084"/>
        <property type="gene ID" value="S2091_3219"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008397">
        <property type="entry name" value="Alginate_lyase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008929">
        <property type="entry name" value="Chondroitin_lyas"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05426">
        <property type="entry name" value="Alginate_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48230">
        <property type="entry name" value="SSF48230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015593366" evidence="1">
        <location>
            <begin position="21"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="domain" description="Alginate_lyase" evidence="2">
        <location>
            <begin position="45"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05426"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="346" mass="38754" checksum="F10F353ED8F2AE15" modified="2018-07-18" version="1">MRKTLIVIALSFITAQAAIAAQATPWCTVDSVPDTTIKSLQKDADKRSADQSRAIARVHTEGTLPHQGIWDQSIEAKKDLPLIRELALIWRVNHDPAVLTHLTTLLDAWASIYQPSFNPIDETDFDAIIDAYAITEVDLPATTRDKVAALLHRWATGYIDQMLHNDKPGKGKWTNNWQSHRIKLATLSAVALGDTRLIDAARWQFLKQINQNLHSNGLSIDFEERDALHYTVYDLEPLVRAAMAARTIGQDWLNLQAENGASLAAGLNWLLPYARGEQTHEEYVHTTVKFDLQRRDAGVAGFTGMWEPKSSGQLYWLASTLDAHYLPVAQSLINQSAWIAACWQAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWP9</accession>
    <name>A0A2S9GWP9_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 9">DNA mismatch repair protein MutS</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">mutS</name>
        <name evidence="12" type="ORF">S2091_3044</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8 9">This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 9 10">Belongs to the DNA mismatch repair MutS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92128">
        <property type="protein sequence ID" value="PRC92128"/>
        <property type="gene ID" value="S2091_3044"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030983">
        <property type="term" value="F:mismatched DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1170.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00096">
        <property type="entry name" value="MutS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005748">
        <property type="entry name" value="DNA_mismatch_repair_MutS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007695">
        <property type="entry name" value="DNA_mismatch_repair_MutS-lik_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017261">
        <property type="entry name" value="DNA_mismatch_repair_MutS/MSH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000432">
        <property type="entry name" value="DNA_mismatch_repair_MutS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007861">
        <property type="entry name" value="DNA_mismatch_repair_MutS_clamp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007696">
        <property type="entry name" value="DNA_mismatch_repair_MutS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016151">
        <property type="entry name" value="DNA_mismatch_repair_MutS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036187">
        <property type="entry name" value="DNA_mismatch_repair_MutS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007860">
        <property type="entry name" value="DNA_mmatch_repair_MutS_con_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036678">
        <property type="entry name" value="MutS_con_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045076">
        <property type="entry name" value="MutS_family"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361">
        <property type="entry name" value="PTHR11361"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01624">
        <property type="entry name" value="MutS_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05188">
        <property type="entry name" value="MutS_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05192">
        <property type="entry name" value="MutS_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05190">
        <property type="entry name" value="MutS_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00488">
        <property type="entry name" value="MutS_V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037677">
        <property type="entry name" value="DNA_mis_repair_Msh6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00534">
        <property type="entry name" value="MUTSac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00533">
        <property type="entry name" value="MUTSd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48334">
        <property type="entry name" value="SSF48334"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53150">
        <property type="entry name" value="SSF53150"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55271">
        <property type="entry name" value="SSF55271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01070">
        <property type="entry name" value="mutS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00486">
        <property type="entry name" value="DNA_MISMATCH_REPAIR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 9 10" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7 9 10" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6 9 10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 9 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA_MISMATCH_REPAIR_2" evidence="11">
        <location>
            <begin position="702"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="628"/>
            <end position="635"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00024647"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS00486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PRC92128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="869" mass="95678" checksum="3C09CCD9C5AC2DE6" modified="2018-07-18" version="1">MAVEDAKHTPMMQQYLRIKADYPDTLVLYRMGDFYELFFEDAEKASRLIGITLTQRGSSGGTPIKMAGVPYHSIDGYLAKLIKLGESIAICEQIGDPATSKGPVERKVMRVITPGTLTETDLLPAKSERPLLSIAVTTQRKQMTLGFAWLSLSSGALKLLEVSTTEKNFSHLLLQECERIAAAEILYTEDVNQPDISALLASLPCKITALPAWHFDFAHAKKSLQEQLGVASLSGFGAEHATSAITAAGALLRYTLATQGKNLRHVNSLRLETVDEFIGLDAVTRRNLELTETIRGQESPTLFSLLDHCRTSMGSRLLRHWLHHPSRAQQQAIARHQAIQTLIESDANPSLLATLSEVPDIERITTRIALASARPRDLAGLRDGLLQLPALCNSLEKCTPATPLLNDLLGALATPDECQHLLEIAIMQEPATMVRDGGVIAAGFDAELDELRGLSENAGQFLIDLETRERAATGIANLRVEYNRVHGFYIEVTNGQTDKVPEHYRRRQTLKNAERYITPELKTFEDKALSAQERALVREKYLYEQVLQQLLPHIIVLQTIAQALAQLDCLVALTEHATRHQWCAPQLVTEPILDIQQGRHPVVENQIERFIANDCQLNADRKLLLITGPNMGGKSTYMRQVALITLLAYVGSYVPANSATIGPIDRIFTRIGAADDLAGGRSTFMVEMTESAAILNAATEQSLVLMDEVGRGTSTFDGLALAWAIAKQLITQTNSYTLFATHYFELTQLPDIHSSAQNVHLSAVEHQETIVFLHAVQDGPASQSYGLQVAQLAGIPNQVIRAARKHLAELEAHSIQSTPQFDLFAEAVPVIETKDEPLQQALDAIDPDSLSPREALDALYQLKKLALTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWQ2</accession>
    <name>A0A2S9GWQ2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Outer membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_3071</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the skp family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92155">
        <property type="protein sequence ID" value="PRC92155"/>
        <property type="gene ID" value="S2091_3071"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.910.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005632">
        <property type="entry name" value="Chaperone_Skp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024930">
        <property type="entry name" value="Skp_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35089">
        <property type="entry name" value="PTHR35089"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03938">
        <property type="entry name" value="OmpH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002094">
        <property type="entry name" value="OMP26_Skp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00935">
        <property type="entry name" value="OmpH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111384">
        <property type="entry name" value="SSF111384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015478665" evidence="4">
        <location>
            <begin position="28"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="85"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR002094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC92155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="171" mass="19717" checksum="8DFCFBAE2EE07A11" modified="2018-07-18" version="1">MKHYAISSLLQLLMASGCMLVVVSATADETKIGFVSTERITRESEPAKASEARLEAEFSQRRKDLQDFTIKIKAMAEKLDKDSPVISESDRLKRQRELSDMDQDFQRKQRAYREDVNQRINEETVKLNERATKVIKQIAEAEKFDIVLQDNVVYFSPRIDITDKVMKALSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWQ8</accession>
    <name>A0A2S9GWQ8_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">50S ribosomal protein L31 type B</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpmE2</name>
        <name evidence="6" type="ORF">S2091_3231</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2 5">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000016">
        <property type="protein sequence ID" value="PRC92096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92096">
        <property type="protein sequence ID" value="PRC92096"/>
        <property type="gene ID" value="S2091_3231"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.830.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00502">
        <property type="entry name" value="Ribosomal_L31_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034704">
        <property type="entry name" value="L28p-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002150">
        <property type="entry name" value="Ribosomal_L31"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027493">
        <property type="entry name" value="Ribosomal_L31_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042105">
        <property type="entry name" value="Ribosomal_L31_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33280">
        <property type="entry name" value="PTHR33280"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01197">
        <property type="entry name" value="Ribosomal_L31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01249">
        <property type="entry name" value="RIBOSOMALL31"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143800">
        <property type="entry name" value="SSF143800"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00105">
        <property type="entry name" value="L31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01143">
        <property type="entry name" value="RIBOSOMAL_L31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC92096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="89" mass="10130" checksum="E5A543163E14DEBD" modified="2018-07-18" version="1">MRDGIHPNYREVVFQDMSIDFKFITRSTINTRDTIEFEGKTYPLVKIEVSAESHPFYTGKHKIVDTAGRVDKFRKKFGTVGSKTAATGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWX0</accession>
    <name>A0A2S9GWX0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Molybdate ABC transporter, ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">S2091_3114</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92198">
        <property type="protein sequence ID" value="PRC92198"/>
        <property type="gene ID" value="S2091_3114"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015412">
        <property type="term" value="F:ABC-type molybdate transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042888">
        <property type="term" value="F:molybdenum ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015852">
        <property type="entry name" value="ABC_transpr_ModC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008995">
        <property type="entry name" value="Mo/tungstate-bd_C_term_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011868">
        <property type="entry name" value="ModC_ABC_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004606">
        <property type="entry name" value="Mop_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005116">
        <property type="entry name" value="Transp-assoc_OB_typ1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43514:SF9">
        <property type="entry name" value="PTHR43514:SF9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03459">
        <property type="entry name" value="TOBE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50331">
        <property type="entry name" value="SSF50331"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02142">
        <property type="entry name" value="modC_ABC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51866">
        <property type="entry name" value="MOP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 9 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 10" id="KW-0500">Molybdenum</keyword>
    <keyword evidence="5 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-1278">Translocase</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="1"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="domain" description="Mop" evidence="12">
        <location>
            <begin position="290"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="29"/>
            <end position="36"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PRC92198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="354" mass="37743" checksum="48792E24EC2E8309" modified="2018-07-18" version="1">MSGVHLQLKLPNLAIDLSLPNIGISAIVGPSGAGKTTLLRAVAGLESVCRGRVDINGAVWQDDTQKIFLAAHQRSVGFVFQEASLFTHLSVQGNLEFGLRRIPVAEQKVSLSQAVELLGIGPLLNRSPATLSGGEKQRVAIARALATSPKLLLMDEPLASLDEPRKAEIFPYLERLHSELEIPLLYVSHATDEVARLADYVVMLDAGQVRASGSVFELLTRADLPFAHGDAASALIGAKVIAHDPHYQLSQFEFSGGILWLPHSATALGNTVRLRIQARDVSLSLTQQIGSSILNSLAVKISAIQGDALGLVMVELDAGGTRLLARITRKSAEQLGLVIGMALFAQIKGVAILK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GX94</accession>
    <name>A0A2S9GX94_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Phenylalanine--tRNA ligase alpha subunit</fullName>
            <ecNumber evidence="13">6.1.1.20</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Phenylalanyl-tRNA synthetase alpha subunit</fullName>
            <shortName evidence="13">PheRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">pheS</name>
        <name evidence="15" type="ORF">S2091_2945</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + H(+) + L-phenylalanyl-tRNA(Phe)</text>
            <dbReference type="Rhea" id="RHEA:19413"/>
            <dbReference type="Rhea" id="RHEA-COMP:9668"/>
            <dbReference type="Rhea" id="RHEA-COMP:9699"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58095"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78531"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.20"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="13">Binds 2 magnesium ions per tetramer.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 13">Tetramer of two alpha and two beta subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 13">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.20" evidence="13"/>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92286">
        <property type="protein sequence ID" value="PRC92286"/>
        <property type="gene ID" value="S2091_2945"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004826">
        <property type="term" value="F:phenylalanine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006432">
        <property type="term" value="P:phenylalanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00281">
        <property type="entry name" value="Phe_tRNA_synth_alpha1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004529">
        <property type="entry name" value="Phe-tRNA-synth_IIc_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004530">
        <property type="entry name" value="Phe-tRNA-synth_IIc_mito"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004188">
        <property type="entry name" value="Phe-tRNA_ligase_II_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022911">
        <property type="entry name" value="Phe_tRNA_ligase_alpha1_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002319">
        <property type="entry name" value="Phenylalanyl-tRNA_Synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010978">
        <property type="entry name" value="tRNA-bd_arm"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11538:SF41">
        <property type="entry name" value="PTHR11538:SF41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02912">
        <property type="entry name" value="Phe_tRNA-synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01409">
        <property type="entry name" value="tRNA-synt_2d"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46589">
        <property type="entry name" value="SSF46589"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00468">
        <property type="entry name" value="pheS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12 13" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="9 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 13" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 13 15" id="KW-0436">Ligase</keyword>
    <keyword evidence="10 13" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11 13" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="14">
        <location>
            <begin position="116"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="259"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="PRC92286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="338" mass="37586" checksum="96A72118027352DC" modified="2018-07-18" version="1">MNSLDNLVTQAGTDFAAAEDAAALENAKAKFLGKTGQITELMKGLGKLSPDERKAQGAIINAIKVQIENLLGARRDQLANAQMQARLNAEAIDITLPGRGRSVGGMHPVMRTWERVEEIFRSIGFDVADGPEIETDWTNFTALNSPENHPARSMQDTFYVEGNDSTGKPLLLRTHTSPMQVRYARMNSAPIKVIAPGRTYRVDSDATHSPMFHQVEGLWIAEDISFADLKGVYLNFVKAFFETDDLQVRFRPSYFPFTEPSAEIDIAFGSGPLKGRWLEVSGSGQVHPSVVRNMGLDPEKYIGFAFGSGLERLTMLRYGISDLRLFYEGDLRFLKQFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXC5</accession>
    <name>A0A2S9GXC5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="8">RelA/SpoT family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_3020</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the relA/spoT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92361">
        <property type="protein sequence ID" value="PRC92361"/>
        <property type="gene ID" value="S2091_3020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015969">
        <property type="term" value="P:guanosine tetraphosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05399">
        <property type="entry name" value="NT_Rel-Spo_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01668">
        <property type="entry name" value="TGS_RSH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004811">
        <property type="entry name" value="RelA/Spo_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045600">
        <property type="entry name" value="RelA/SpoT_AH_RIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007685">
        <property type="entry name" value="RelA_SpoT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004095">
        <property type="entry name" value="TGS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012676">
        <property type="entry name" value="TGS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033655">
        <property type="entry name" value="TGS_RelA/SpoT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13291">
        <property type="entry name" value="ACT_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19296">
        <property type="entry name" value="DUF5913"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04607">
        <property type="entry name" value="RelA_SpoT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02824">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00954">
        <property type="entry name" value="RelA_SpoT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81271">
        <property type="entry name" value="SSF81271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00691">
        <property type="entry name" value="spoT_relA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51831">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51880">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HD" evidence="6">
        <location>
            <begin position="102"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="domain" description="TGS" evidence="7">
        <location>
            <begin position="443"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="domain" description="ACT" evidence="5">
        <location>
            <begin position="698"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC92361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="773" mass="86812" checksum="D734B54F36D25D9C" modified="2018-07-18" version="1">MSLTPSERSPAETRSRAKGKRSSVPVSAVKADHQANPQPDNNADRQADPIEIPQHISHVSITQLSEKLSAYLPASDLISVRDAFRFSDEMHLGQMRRSGEPYISHPIAVAEICADWKLDAQAIMAALLHDVMEDQDVKKEELLERFGAPVASLVDGLSKLEKIEFQSQIEAQAENFRKMLLAMARDVRVILVKLADRLHNMRTLSVMTPEKQRRIARETMEVYVPIAHRLGLNNIYRELQDLSFAHLYPLRYRTLAKAVKAARGNRREVVGKILDAVNSTLEAAGINAEVQGREKTLYGIYRKMQDKNLSFSQVLDVYGFRVVVNNFTESYYALGILHGLYKPMPGKFKDYIAMPKLNGYQSLHTTLIGPYGTPVEFQIRTHDMHHIAESGVAAHWLYKDEQVSLSDLQVRTHAWLQSLLDIQKQTGDSAEFLEHVKVDLFPDSVYVFTPKSKIIALSRGATALDFAYTIHTDIGDQTIAAKINHEPAPLRTELRSGDIVEIITSPNSRPTPNWLSYVRTGKARSAIRHYLRTSNLTESTELGRQLLSQSLTLLNLTPKLPEDIVEKLLFESGAKTLEELYADIGIGRRMSTLVARHILDLIEDEPSSIPFLQLLNENPTVTKLNPVLIYGCDGISVELANCCLPIPGDEIIGQLKRDQGLVVHTCDCPTGKRQLQKEPERWIDVAWGQELNRRFDCKITIFTTNERGALARVAAEIGDSDANIINVEMEGSSSDSLSQICFTIQVEGRKHLARLMRNVRHIIGVSKIMRGQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXR3</accession>
    <name>A0A2S9GXR3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2892</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92517">
        <property type="protein sequence ID" value="PRC92517"/>
        <property type="gene ID" value="S2091_2892"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="8"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="207" mass="22085" checksum="8AE331C74DAB9B92" modified="2018-07-18" version="1">MTITPTKLIFLPGAGGSAEFWHPVASLLTHPASRVLLGWPGFGSVPANSDVQNIDDLVALVVDEIDQPSALLAQSMGGVVAIQAALKRPELITHLVLAATSGGVNMSDLQVADWRQAFIEANPTFPRWFADYNDDLSTSIVAIQAPTLLLWGDSDLISPIDVGLRLKELLPSSRIHVLPNGEHDFASKLAASVAPLIDTHLNNARST</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXY4</accession>
    <name>A0A2S9GXY4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_2642</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92587">
        <property type="protein sequence ID" value="PRC92587"/>
        <property type="gene ID" value="S2091_2642"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="9"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="147"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC92587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="216" mass="23543" checksum="48C1D88338A5D164" modified="2018-07-18" version="1">MKEQAAAIRVLLADDHPIVMTGFAMSLQGQGIEVIGQAKTPLEAIQQYTALQPDVVILDIRFGEQLSGFDVAKTILQNHPSARIIFLSQFDQDSFIKEAYRLGGRAFVTKDCDPAELAQAVRKAHAGDLVFLPVIAERLANLSVQKDSSPQTLLDSRALTIFTLLAEGLTNAEIAEQLDISIKTVSNVSQVIKEKLGIQRQADLTKLALKHGLIQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYH9</accession>
    <name>A0A2S9GYH9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Sodium/hydrogen exchanger family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_2515</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92785">
        <property type="protein sequence ID" value="PRC92785"/>
        <property type="gene ID" value="S2091_2515"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015299">
        <property type="term" value="F:solute:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006812">
        <property type="term" value="P:cation transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006153">
        <property type="entry name" value="Cation/H_exchanger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00999">
        <property type="entry name" value="Na_H_Exchanger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="16"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="42"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="68"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="97"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="126"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="159"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="193"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="229"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="271"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="296"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="336"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="365"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="domain" description="Na_H_Exchanger" evidence="5">
        <location>
            <begin position="19"/>
            <end position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC92785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="401" mass="43080" checksum="F447AE7C11DF5212" modified="2018-07-18" version="1">MNNLILPAWPLQLNDTMYLALALVFSGLAGEVMKRVVRLPRVCGYALAGLLLGPLMFGWFGAHNIGSLRIFIDLALALLLFELGNRVDLCWFRLNPWIIPSSIAEAGLTFIGTYTVLRLFDATPGFAATVAAIAISTSPAVVMRVAAELRAEGQVTQRLYVLTALNVLYSVVLSKLIMGYLHGAFHHDWSSAIFHPVYLLLGSLFMGGLIALAFRLLRRWSDLSNEQAVVILFGLLLLSLSLLQALMLPTMLAPLLAGVMVKNSDRRPLNWPHHFGTAGGVLVILLFILTGATLTANAMITGGVAALAVIAVRLFGKGIGVAVFGPVSGLSLRQSFALGVALMPMSALAFLLVDDISTLYPEFGAQVGGIVLSMVAILQLVGPIGVQWALRFCNESIERGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYM3</accession>
    <name>A0A2S9GYM3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glutathione S-transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2555</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92825">
        <property type="protein sequence ID" value="PRC92825"/>
        <property type="gene ID" value="S2091_2555"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026928">
        <property type="entry name" value="FAX/IsoI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033468">
        <property type="entry name" value="Metaxin_GST"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012336">
        <property type="entry name" value="Thioredoxin-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17171">
        <property type="entry name" value="GST_C_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17172">
        <property type="entry name" value="GST_N_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01200">
        <property type="entry name" value="SUF1.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="SSF47616"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thioredoxin-like_fold" evidence="2">
        <location>
            <begin position="18"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="domain" description="GST_C_6" evidence="1">
        <location>
            <begin position="164"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF17171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="232" mass="25829" checksum="B14DDAD31C09931A" modified="2018-07-18" version="1">MITLHTFGSSFGLPDASPFVMKAELLLKMSGLAYQTDSTTGFKNAPKGKLPSIRDGDALIADSTLIRWHLEHKYQIDFDKNLSAQEKGIAWAVEKLLEDNLYWALLDARWVNDANFKRGPAQFFKAVPLPMRGLVKAMVRRQIAKNLKAHGLGRHTQQEILAIASKNIEAVASILGDKPYLMGEHPSGADATCAAFIWGALCPYFETPIRAAAEKHPNLVAYVERMRAQYYP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYT5</accession>
    <name>A0A2S9GYT5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2546</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92816">
        <property type="protein sequence ID" value="PRC92816"/>
        <property type="gene ID" value="S2091_2546"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="75"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="110" mass="11449" checksum="95C52F4E42D5CEDC" modified="2018-07-18" version="1">MMVASIGSSAYSSVTGSFNTPASSTSNPQISALQSQLIVLRQQLVITQCVQTQKTLTQQITNVQAQITLLQNTSTAPNTSIPSTTTAIQNNTSTTNSTTATLGNSINTLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYY2</accession>
    <name>A0A2S9GYY2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">4Fe-4S single cluster domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_2315</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92898">
        <property type="protein sequence ID" value="PRC92898"/>
        <property type="gene ID" value="S2091_2315"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043365">
        <property type="term" value="F:[formate-C-acetyltransferase]-activating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012837">
        <property type="entry name" value="NrdG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034457">
        <property type="entry name" value="Organic_radical-activating"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30352">
        <property type="entry name" value="PTHR30352"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30352:SF2">
        <property type="entry name" value="PTHR30352:SF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC92898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="224" mass="24680" checksum="7694ACAE0A34AA7A" modified="2018-07-18" version="1">MQNSKTKININKAHFPVTVLGPGRRIGIWLQGCSIGCKNCVSQDTWDATPSRLMTVAQLLTWCKQTSDAQEMDGITISGGEPFDQPAALSALLDGLHQWRTSSQHGFDILCYSGYPLTTLQKNHSAILAKLDALIPEPYIDNKPLTDLWRGSSNQSLQLLSARAEQKYAPYLNNSVVESGKHIQAMLDGKKVWYIGIPARGDMAALEALCQERGVTFDSASWRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYY6</accession>
    <name>A0A2S9GYY6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Etoposide-induced protein 2.4 (EI24)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2366</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92949">
        <property type="protein sequence ID" value="PRC92949"/>
        <property type="gene ID" value="S2091_2366"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="89"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="128"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="154"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="198"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="226"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="264" mass="29692" checksum="0B3DB3270EC7B35F" modified="2018-07-18" version="1">MKKVLISYGRAFLLQFNIKMLLLSLLPSVLALGLWAVVLYFSLQPLIDFLQQYFIDNNGFQLAGNILGFLGLLTLKAVIVPLIAMWLLLPLMLLTALLFVACIAMPLINRKVSQQYYPQLEKKHGGGWWSSLGYALVCVVIFVFAWLISLPLTLFMHLGLIIQPVLLGWVTYRVMAHDALAVHASAEERKIILKQHRWQLWTVGIIAGLLGALPGMVWLGGVLSVVFLPLLAAVAIWLYVLVFMFSGLWFQLFCLDALQQLRQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZ37</accession>
    <name>A0A2S9GZ37_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2411</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92994">
        <property type="protein sequence ID" value="PRC92994"/>
        <property type="gene ID" value="S2091_2411"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015778132" evidence="2">
        <location>
            <begin position="21"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="120" mass="11624" checksum="468D35B7A1C25B8C" modified="2018-07-18" version="1">MNKFITTLLAATLATGAAFAQTPAATPAVPAMPAVKAMAASSAASATSDVKAAAAVPAATASKAASKVEGKVTTKATQATSTAKTVTQSTATSAVEKGTAKVATVKKEVKAEAVKDASTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZ45</accession>
    <name>A0A2S9GZ45_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Microcystin-dependent protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2394</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92977">
        <property type="protein sequence ID" value="PRC92977"/>
        <property type="gene ID" value="S2091_2394"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1340.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011083">
        <property type="entry name" value="Phage_tail_collar_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037053">
        <property type="entry name" value="Phage_tail_collar_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07484">
        <property type="entry name" value="Collar"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015640355" evidence="1">
        <location>
            <begin position="27"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="domain" description="Collar" evidence="2">
        <location>
            <begin position="32"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="199" mass="20154" checksum="A3D000469F2D9D34" modified="2018-07-18" version="1">MFSSTRALAVASLSALLGLSALPASAQTPYLGEIKCFGYNFVPQGWAALNGQLMSIAQNTALFSLLGTQFGGDGIQTFALPDMQGRTLIEVGNGAGLSSHVVGESAGNETTGLTIANLPPHTHTFAPLGSTNDASSVSPAGQVASSKARTTLYTSPSGIVTMASGVTSATGSGVPINNMQPYLAVTCAIALQGIYPSRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZC2</accession>
    <name>A0A2S9GZC2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">TPR repeat</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_2139</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93053">
        <property type="protein sequence ID" value="PRC93053"/>
        <property type="gene ID" value="S2091_2139"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013217">
        <property type="entry name" value="Methyltransf_12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001440">
        <property type="entry name" value="TPR_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08242">
        <property type="entry name" value="Methyltransf_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00515">
        <property type="entry name" value="TPR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="82"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="116"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="150"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="184"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="218"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="domain" description="Methyltransf_12" evidence="3">
        <location>
            <begin position="352"/>
            <end position="442"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC93053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="510" mass="57411" checksum="57002054DBF8929D" modified="2018-07-18" version="1">MNIKTINSIPELLQHAVKLHQQGELASAKNRYQQILQINPHQFEALHFLGVIAKQTGNPLEAISLISAAINTVTTALNANHASAFCNLGTAFQDCGQTEQALKNYQQAILLKPDYSIAHNNLGNTFKNCGKLEAAIHSYENALHYHPNYPDAYYNCGTTYQLQQQYTKALNCFERAIQLKTNYPAAYFARGVAFQSLYDYESALVSYDQAITLQPDYSEAYLNRGITLNKLQQFQAALDNFELAIHYQKNYAKAHHYRANTLRQLMRIEDAIEAYQCALELGADSQQITFALAALGVGAPPSAPPTTYVKELFDHYAEHFDVHLVDVLKYEMPQIVATAIEKYRMRDQLDSLDLGCGTGLCGSYLRPYSRTLTGVDLSQKMLDKASQLKHYDQLICTEITEFLSEKIDNFDLVCAADVLVYIGDLSGVFSRVHQALRSGGLFCFSVEEAAEEIQGHDFILKATNRYAHTEQYIRHLANLYDFKIHEITQQVARQENQKNSSALVTLLSRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZN6</accession>
    <name>A0A2S9GZN6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltransferase small domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2254</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93168">
        <property type="protein sequence ID" value="PRC93168"/>
        <property type="gene ID" value="S2091_2254"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044260">
        <property type="term" value="P:cellular macromolecule metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043412">
        <property type="term" value="P:macromolecule modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006807">
        <property type="term" value="P:nitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044238">
        <property type="term" value="P:primary metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007848">
        <property type="entry name" value="Small_mtfrase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05175">
        <property type="entry name" value="MTS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="MTS" evidence="1">
        <location>
            <begin position="181"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="392" mass="43235" checksum="3301F4B8BCC91E23" modified="2018-07-18" version="1">MKPIHEILQWQDAQQTQHIVWRAENGVTAPKKFIVADDTLTADSAYKLACEGCGLLWQGDFQNARQLLQALARRCDRPDKKPRKAAKEAVEPTSAQVFNLHRQAQSQRARILAMVLIPLNSDYTIPLKRAPNVLDACTEAYGKLTEATPNSIVSLRELQGLIGAHEWRKKGVAIPELEANIHPHYGVFSPVRGEYIGLVANAVLPNTQLAFDIGTGTGVLAAVLAKRGVQRVIATDQDPRALACAQENLQRLGFLNQVQLTSVDLFPEGKAPLIVCNPPWVPARPSSPIEYAIFDPESRMLKGFLAGLAEHLDVNGEGWLLLSDFAEHLGLRTRAELLLWIEQAGLQVAERIDVKPTHPKVVDQTDPLHTARAAEITSLWRLTANLLATKSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZS4</accession>
    <name>A0A2S9GZS4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_1941</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93203">
        <property type="protein sequence ID" value="PRC93203"/>
        <property type="gene ID" value="S2091_1941"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014757">
        <property type="entry name" value="Tscrpt_reg_IclR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005471">
        <property type="entry name" value="Tscrpt_reg_IclR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09339">
        <property type="entry name" value="HTH_IclR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01614">
        <property type="entry name" value="IclR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00346">
        <property type="entry name" value="HTH_ICLR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51077">
        <property type="entry name" value="HTH_ICLR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51078">
        <property type="entry name" value="ICLR_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH iclR-type" evidence="3">
        <location>
            <begin position="11"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="domain" description="IclR-ED" evidence="4">
        <location>
            <begin position="74"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC93203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="248" mass="26667" checksum="D0113A1B674B6171" modified="2018-07-18" version="1">MPNSPSSSSVIPTGERALQVLALVARHGSSLTARELATQAKLPLSSLYRHLASLKKWGLVQEHGQSGLYQPGPLSLQLAWGFDHHSYLMQVAHAEMVSLVEKSGESVGLLVYLNGQIICLDMLESQQALRCSFSKGRANSVVHGASAKALLAHLPGALLAAILAEHPTEAQYLPAQLEQCRQQGYVVSVGEVDADVWGVSAPIFSSKKRVECTISLMAPNARAQLREPELIELTLAAAARIGRQLSDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZT9</accession>
    <name>A0A2S9GZT9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="8">DNA internalization-related competence protein ComEC/Rec2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_2222</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93136">
        <property type="protein sequence ID" value="PRC93136"/>
        <property type="gene ID" value="S2091_2222"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030420">
        <property type="term" value="P:establishment of competence for transformation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07731">
        <property type="entry name" value="ComA-like_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035681">
        <property type="entry name" value="ComA-like_MBL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004477">
        <property type="entry name" value="ComEC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004797">
        <property type="entry name" value="Competence_ComEC/Rec2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025405">
        <property type="entry name" value="DUF4131"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03772">
        <property type="entry name" value="Competence"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13567">
        <property type="entry name" value="DUF4131"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00360">
        <property type="entry name" value="ComEC_N-term"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00361">
        <property type="entry name" value="ComEC_Rec2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="53"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="268"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="311"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="337"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="373"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="426"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="452"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="482"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="domain" description="Lactamase_B" evidence="7">
        <location>
            <begin position="570"/>
            <end position="743"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC93136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="829" mass="92299" checksum="EB4975D724382A4B" modified="2018-07-18" version="1">MRSTIIGFVLGVLLLQQQRSLWEWPALAALICVAVLIFLSLRWVHRAALCNLFMLLVGGLSGWVWASGFAIVALSTRLAPEIEEQDIAVVGVISSLPSQSDYGQRFQFSIERVLTPNVNSAHMPDKVLLSWYEANSFQRSNPQVKTQSTTPLQAGERWQLNVRLRRPHGLANPYGFDYEVWLLEQGLDATGTVRNDRNNAIKNQQLNSFAFSVKNCIEWARGKLRNRILSALPNQPYAPVLVALVIGEQGAIRQSDWQVFARTGISHLISISGLHVTMLSGMCANLMFYLWRKSFFTRYQLPLILPAHKAAALSGFLMALIYVALAGFGVPAQRTLIMIAVLALALWMDRVTSVSNVLCLALALVLLVDPWAVLWPGFWLSFSAVGIIFFVSLGRREMKAVEQFSLSPKPSIRASKFFQHIRQASTIQYAITLGLVPLTMLLFNQVSIVSPIANAVAIPIVSLLVTPFALLGSVLPAPIGTWVLVLTNFILQYLISFLGWLSQLSWAVWQAPRPEVWMFLCAFAGTFWCLAPKGWPLRWAGLLAWLPLCLNSSNFPAPGEFKVTALDVGQGMALLIETERHRLLYDTGPSYSPESDAGSRVIYPYLKMRGINQLDGLMISHNDSDHSGGALSLMQQLKINWVASSLALDSTIVQTAQQQSQHITCLAGQSWEWDGVQFEVLHPPAVIYTSDKWKPNAKSCTLKITNGAHSLLLAGDIEAIQEDQLVNSIPEKLSATVLLAPHHGSGTSSTTEFLREVNPQLAIFQLGYHNRYRHPKSSVWQRYADFGITRLRNDDAGAITLKFGAEVSFEEYRVTDARYWHPTLSADRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H010</accession>
    <name>A0A2S9H010_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">PEP-CTERM protein-sorting domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_1944</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93206">
        <property type="protein sequence ID" value="PRC93206"/>
        <property type="gene ID" value="S2091_1944"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013424">
        <property type="entry name" value="PEP_exosort_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07589">
        <property type="entry name" value="PEP-CTERM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02595">
        <property type="entry name" value="PEP_exosort"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015598785" evidence="2">
        <location>
            <begin position="23"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="188"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="domain" description="PEP-CTERM" evidence="3">
        <location>
            <begin position="184"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC93206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="211" mass="21877" checksum="A9841B83A5D909D5" modified="2018-07-18" version="1">MKKIVALVIAVLMTAAGSTAYATPTVSVGIGSFSSGPDITFETLSNSTPITNQYSGLGVTFSNFWADTSYGTTFFSDAGNVGADNFAGPGGCCTSSATINFTTDYSMVGFEIVSNGNTTINVLSANNEMDTFNFNARPNSNSGIFVGLENLSGISEISFGPSAENDAFLIDNIRLEGAAPQPGTVPEPGILALLGIGLIGFYFARRKKQAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H020</accession>
    <name>A0A2S9H020_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ATP-dependent dethiobiotin synthetase BioD</fullName>
            <ecNumber evidence="5">6.3.3.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">DTB synthetase</fullName>
            <shortName evidence="5">DTBS</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Dethiobiotin synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">bioD</name>
        <name evidence="6" type="ORF">S2091_2070</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>(7R,8S)-7,8-diammoniononanoate + ATP + CO2 = (4R,5S)-dethiobiotin + ADP + 3 H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:15805"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:149469"/>
            <dbReference type="ChEBI" id="CHEBI:149473"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.3.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="5">Cofactor biosynthesis; biotin biosynthesis; biotin from 7,8-diaminononanoate: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the dethiobiotin synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.3.3" evidence="5"/>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93332">
        <property type="protein sequence ID" value="PRC93332"/>
        <property type="gene ID" value="S2091_2070"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00078">
        <property type="reaction ID" value="UER00161"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004141">
        <property type="term" value="F:dethiobiotin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009102">
        <property type="term" value="P:biotin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00336">
        <property type="entry name" value="BioD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004472">
        <property type="entry name" value="DTB_synth_BioD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43210">
        <property type="entry name" value="PTHR43210"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006755">
        <property type="entry name" value="DTB_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00347">
        <property type="entry name" value="bioD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 5" id="KW-0093">Biotin biosynthesis</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" evidence="5">
        <location>
            <position position="42"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="17"/>
            <end position="22"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="21"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="59"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="123"/>
            <end position="126"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="123"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="183"/>
            <end position="184"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="212"/>
            <end position="214"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC93332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="240" mass="25619" checksum="7924B75D3C7C9239" modified="2018-07-18" version="1">MEYKKPLAFFVAGTDTEIGKTLVSSALLYGMVQQGLQSIGMKPVAAGAFLQDGVWCNEDVLALKDAGNVILPAELSKLVNPYLFKLAAAPHIAAQQEMQQINLSVILDCYQQLTTYAQALIVEGVGGFRVPLNAQEDSADMAQQLNLPVVLVVGMRLGCISQALLTVEAITARGLTVAAWVANCAQGEMAHLQDNLIALQERINAPLLGCIPCLDKPTAQAAAAHLDLTKLLKLPEQLIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0A5</accession>
    <name>A0A2S9H0A5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2034</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93296">
        <property type="protein sequence ID" value="PRC93296"/>
        <property type="gene ID" value="S2091_2034"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014547">
        <property type="entry name" value="UCP028477"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09916">
        <property type="entry name" value="DUF2145"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028477">
        <property type="entry name" value="UCP028477"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015741917" evidence="1">
        <location>
            <begin position="25"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="265" mass="29910" checksum="FC9B72C89A969056" modified="2018-07-18" version="1">MTRLKLVSCGLLLLVGCWLNPAFAGRSCDDVQSNPTSIMKGLELAQKTKLALDDSGAELAIIARVGQDLSKYNLRYSHLGLVYREPNGRWNVLHELNQCGTAESSLFNEGLGNFFMDDVFAYETMLIIPNEDQQKKLKELIDTKVALQLHDAHYNMLAFPFSTKYQNSNQWALELLAAGQSKDIVITNRGQAQNWLKLAGYQPSELNIPALTRLGARMFRANVAFDDHPMDRRMAGKIDVVTVESINQFMQMRDPQIKRIVLTYP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0B8</accession>
    <name>A0A2S9H0B8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1812</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93425">
        <property type="protein sequence ID" value="PRC93425"/>
        <property type="gene ID" value="S2091_1812"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="617"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="621"/>
            <end position="644"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="644" mass="69925" checksum="65016FDF04C8A9FE" modified="2018-07-18" version="1">MSYLQFPRLAFSGLFQADVSTVNNDPRHFDIDHFDSSFQEFQSNSASGGTTFNGWWNPVGTGIFRFHECATQSISTQAGQTQTKASQDPAIGLTVGNAMGRASGKLVDLDPDWQNASCLYGLGVTLINANGHVIMSADYASNPFRDLWFTRANSAGDMGASAMFQSVLTNVIWNLDGIQSPFFDQLIAATEQDMLSIRLTTYGYNMNAKAPLFGYGTVLGVIGAAKASQPRSFILGRRFTPTTQNAAMDLVSSNGIGCFSAQIDSTNSSLHVDLSNALPLAKGYVVQDLGPMQFALLKNPLTAQDDVINAEDYIALAAVDQSQELQLQQGGIQSVPLPTSINEDLHNHPLAILSAPDANGKMLVSVRENLLGLEVRADTFAFRLDPNDPHKNHAQSTFYAACYGIPMPNAALGFWVSGPALDYANTPVSAPPGTTPKALLPVNNVPDNAIRFSPARPVTDAEGKVQVQLHGPEEMQTPREYIDGQLYTISYNFAGNDPALQQTYDKLAAVVFTKIAPCPSPTWEDIYPILKQYANLYPIMSQGLLDFSKKEQADANAFILHFVFDKHIDDPDQMPVTRDLSSAKRTMLIRYFQQIIDSQGMPKNAMDMFGKRCPTRGGGGLAQAHQQSAATCPNLPGKSRGPNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0G4</accession>
    <name>A0A2S9H0G4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ABC-type antimicrobial peptide transport system ATPase component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_1859</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93472">
        <property type="protein sequence ID" value="PRC93472"/>
        <property type="gene ID" value="S2091_1859"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03255">
        <property type="entry name" value="ABC_MJ0796_LolCDE_FtsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017911">
        <property type="entry name" value="MacB_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-1278">Translocase</keyword>
    <feature type="domain" description="ABC transporter" evidence="7">
        <location>
            <begin position="14"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="50"/>
            <end position="57"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC93472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="239" mass="26303" checksum="98D161EC61E1FCBF" modified="2018-07-18" version="1">MHDATGTKIKKEAIVANEVTKWFGEGDTKMTAVNRVNFVAHFGEILFIVGPSGSGKTTLLSMVSGILRPNAGTVTVNGTDIWTLNNDQLAEFRLNTMGFVFQDYHLFPRLTSAENVAIPLILKQRDWDESIAEARKYLEIVGLKNRAEILPVKLSGGEQQRVAIARAIVGGPQILILDEPTASLDGDTGKMIIAFVKEKILNENRCIVIITHDARINEFADRIIHMEDGCITGLDKGTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0I6</accession>
    <name>A0A2S9H0I6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1847</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93460">
        <property type="protein sequence ID" value="PRC93460"/>
        <property type="gene ID" value="S2091_1847"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015616587" evidence="1">
        <location>
            <begin position="24"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="119" mass="12731" checksum="DBDBA06D2D7B1301" modified="2018-07-18" version="1">MLNKLICFIFSSFLLLTLGVGNAQEIKDVEATYAISSKTIIDPAPGEKKDRVLLFLTGTGAKEIYDSILNPPKSSQCGPNLVVKSANNLECIKDTKTGTYQCRIGVMLDSGKTVKGGAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0I7</accession>
    <name>A0A2S9H0I7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1763</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93376">
        <property type="protein sequence ID" value="PRC93376"/>
        <property type="gene ID" value="S2091_1763"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009822">
        <property type="entry name" value="YaeQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038590">
        <property type="entry name" value="YaeQ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38784">
        <property type="entry name" value="PTHR38784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07152">
        <property type="entry name" value="YaeQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF011484">
        <property type="entry name" value="YaeQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01322">
        <property type="entry name" value="YaeQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="182" mass="20825" checksum="B7D21E73D4E493AE" modified="2018-07-18" version="1">MALKSTVYKVELQLSDMDRNYYAAHSLTLARHPSETDERMMVRLLAFALNASENLVFAKGLSDIEEPDIWHKDYTGAIQQWIEVGQPDERRLLKACGRAEQVLVYSYASNSAIWWQGLGNRLERAKNLTVWNVPVATSQALEKMAQRNMQLQCTIQDGQLWLTDDTNTVQVDLVSLKQPFSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0Q7</accession>
    <name>A0A2S9H0Q7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein, PEP-CTERM system associated</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1917</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93530">
        <property type="protein sequence ID" value="PRC93530"/>
        <property type="gene ID" value="S2091_1917"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017467">
        <property type="entry name" value="CHP03016_PEP-CTERM"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03016">
        <property type="entry name" value="pepcterm_hypo_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015438478" evidence="2">
        <location>
            <begin position="37"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="579" mass="62412" checksum="BF95FD4DE76CDF42" modified="2018-07-18" version="1">MVAIMAKQSMGKKSRLYTLLAAAFVAPLSLGLPSFAQTNPQTGGGTTNGTPAATVNGQANGGTTSGTTAANAQANEETSNGASTPTVNAQARGWTITPSVNLSETYTDNVKLQPAGQATSAFITEVAPGIDITAATRRLKLDLDYAVQNLHYSGDDLGNERTNQQLNAKSKLDLIDNFFYIDGTANISQQNQTPFGPDTTNNLNLSDNRVTIRTYSLSPYLHETFQQTATGELRYSRDSVATSLSGLTNSTADTIQASLKSGSAFKAFNWDFESSDQKIHYTDESDIEMQSNILNFGYHFSSQFELTGDAGYEKNNYVALNSEAPAGTTWSGGFAWTPSDRTNVAASVGKHYYGNSYMFSLNQRTRATVWTLGYNESITTTRSQYLLPVTTNTSALLNSLWQASIPDAAQRQQAVNAFIQENGLPSALNSSVNTLANQVFLQKSLLGSVAITGAQNTVMLNLFNIQRDAQSVSIVDDTGLLGNTNQALLNNTRQTGANALWSVKFGPRTDASIMTGYTRAVSNSTGITYNNKSTTLTFSHQLQPKLKAMLELMRLQNDSNVSTGDFKENAISVFLLLGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0R0</accession>
    <name>A0A2S9H0R0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Bacterial regulatory protein, tetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1576</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93575">
        <property type="protein sequence ID" value="PRC93575"/>
        <property type="gene ID" value="S2091_1576"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="12"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="221" mass="24933" checksum="A138C96D8C225F81" modified="2018-07-18" version="1">MNPPAKIMRKGELTRAAILEAALQVASRDGLEGLTIGLLADQMHMSKSGVFAHFGSREDLQIDVIKLYHANFEHEVFYPSLKQKRGLPRLTSMFLLWVNRVSVEVASGCIYISGAVEYDDRPGELREKLSWMVTTWQQALRRATVQAIDCGDLKSDTDPDQLVFEMYGLILALHHDARFLKIPGSFERAQNGFERLIKHYGSTVMVDPVDPLPKEQALFTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0Y6</accession>
    <name>A0A2S9H0Y6_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Proton-translocating NAD(P)(+) transhydrogenase</fullName>
            <ecNumber evidence="3">7.1.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">S2091_1611</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H(+)(in) + NAD(+) + NADPH = H(+)(out) + NADH + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:47992"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="7.1.1.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.1.1.1" evidence="3"/>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93610">
        <property type="protein sequence ID" value="PRC93610"/>
        <property type="gene ID" value="S2091_1611"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024605">
        <property type="entry name" value="NADP_transhyd_a_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12769">
        <property type="entry name" value="PNTB_4TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-0521">NADP</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-1278">Translocase</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="60"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="domain" description="PNTB_4TM" evidence="11">
        <location>
            <begin position="10"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF12769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PRC93610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="109" mass="11662" checksum="970C542A2337F4A9" modified="2018-07-18" version="1">MEVSHTLTNLIIFVLAIYVGYHVVWTVTPALHTPLMAVTNAISAIIIVGAMLAAGLTEGLLAQVMGTLAVALAAVNVFGGFLVTQRMLEMFKKKEPKKAQVSADSKEHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H103</accession>
    <name>A0A2S9H103_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 13">DNA polymerase I</fullName>
            <ecNumber evidence="3 13">2.7.7.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">polA</name>
        <name evidence="17" type="ORF">S2091_1660</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12 13">
            <text>a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="2">Single-chain monomer with multiple functions.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 13">Belongs to the DNA polymerase type-A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="3 13"/>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93659">
        <property type="protein sequence ID" value="PRC93659"/>
        <property type="gene ID" value="S2091_1660"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006261">
        <property type="term" value="P:DNA-templated DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd09898">
        <property type="entry name" value="H3TH_53EXO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002562">
        <property type="entry name" value="3'-5'_exonuclease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020046">
        <property type="entry name" value="5-3_exonucl_a-hlix_arch_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002421">
        <property type="entry name" value="5-3_exonuclease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036279">
        <property type="entry name" value="5-3_exonuclease_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019760">
        <property type="entry name" value="DNA-dir_DNA_pol_A_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001098">
        <property type="entry name" value="DNA-dir_DNA_pol_A_palm_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020045">
        <property type="entry name" value="DNA_polI_H3TH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018320">
        <property type="entry name" value="DNA_polymerase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002298">
        <property type="entry name" value="DNA_polymerase_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008918">
        <property type="entry name" value="HhH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10133">
        <property type="entry name" value="PTHR10133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01367">
        <property type="entry name" value="5_3_exonuc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02739">
        <property type="entry name" value="5_3_exonuc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00476">
        <property type="entry name" value="DNA_pol_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01612">
        <property type="entry name" value="DNA_pol_A_exo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00868">
        <property type="entry name" value="DNAPOLI"/>
    </dbReference>
    <dbReference type="SMART" id="SM00474">
        <property type="entry name" value="35EXOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00475">
        <property type="entry name" value="53EXOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00279">
        <property type="entry name" value="HhH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00482">
        <property type="entry name" value="POLAc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47807">
        <property type="entry name" value="SSF47807"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="SSF56672"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="SSF88723"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00593">
        <property type="entry name" value="pola"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00447">
        <property type="entry name" value="DNA_POLYMERASE_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0227">DNA damage</keyword>
    <keyword evidence="13" id="KW-0234">DNA repair</keyword>
    <keyword evidence="13" id="KW-0235">DNA replication</keyword>
    <keyword evidence="11 13" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="10 13" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="9" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6 13" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="53EXOc" evidence="15">
        <location>
            <begin position="2"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="domain" description="3'-5' exonuclease" evidence="14">
        <location>
            <begin position="322"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="domain" description="POLAc" evidence="16">
        <location>
            <begin position="677"/>
            <end position="883"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020311"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00024632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU004460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM00475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="SMART" id="SM00482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="PRC93659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="919" mass="100955" checksum="826AF25757D8D553" modified="2018-07-18" version="1">MQKTLLLVDGSSYLYRAFHAMPDLRNATNQPTGAIYGMISMLRRLRSDYPSAYMACVFDAKGKTFRDDLYAEYKAQRPSMPEDLAAQIIPIHEVVRNMGWPILMVEGVEADDVIATLAVDSVKLGLKCIVSTGDKDLAQLVNQDVTLINTMTNEKLDVAGVVTKFGVPPNRIVDYLSLIGDTVDNVPGVAKVGPKTALKWLGLYDSLDGVMAHANEISGVVGENLRQALDWLPQARVLVTVKTDCDLSAHSKSITESLVAQPEDNAAMIDFFTRYGFKSWLRDATAQQAGGAEVSASEKTNVPEVSAQVAPVTVKPAVATNYETILTEAALNQWLEKIQQAELTSIDTETTSLEPMTAQLVGISLCCEVGHAAYIPVAHRYADAPEQLSRDFVLARLKSWLEDDTQRKVGQNLKYDSHIFANHGVTLRGVAHDTLLQSYVFESHKSHDMDSLAMRHLERKTISFEEVCGKGANQICFDQVDIALATNYAAEDADITLQLHQAMFPQVENDAKLLYIYKAIELPTAQVLQKIERNGVLIDAQLLATQSNQIGTRLLELEQQAYELAGQPFNLNSPKQLGEILFGKLQLPVVKKTPSGAPSTDEEVLQKLAENYPLPKVLLENRGLAKLKSTYTDKLPKMVNATTGRVHTNYAQAVAVTGRLASNDPNLQNIPIRSVEGRRIREAFVASAGSVIVSADYSQIELRIMAHISGDASLLRSFAEGEDVHRATAAEIFGITPAEVSSEQRRYAKVINFGLIYGMSAFGLAGNLGIERAAAQSYIDKYFSRYPGVAHYMAETKVKAREQGYVETVFGRRLWLAEINSSNGQRRQGAERAAINAPMQGTAADLIKLAMIAVQQWLETSSLKSKMIMQVHDELVLEVPEDELALVKQKLPELMAQVATLKVALIAEVGVGPNWDKAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H112</accession>
    <name>A0A2S9H112_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Dienelactone hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1648</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93647">
        <property type="protein sequence ID" value="PRC93647"/>
        <property type="gene ID" value="S2091_1648"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002925">
        <property type="entry name" value="Dienelactn_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019546">
        <property type="entry name" value="TAT_signal_bac_arc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01738">
        <property type="entry name" value="DLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10518">
        <property type="entry name" value="TAT_signal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DLH" evidence="1">
        <location>
            <begin position="68"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="294" mass="31992" checksum="93A593BA9808CFDF" modified="2018-07-18" version="1">MQHLQSEFDSLVGGKDKTIDRRDFIKTAVGVGFAAAVLPVCAKTLIRTDAEGLKDGEFTLEIAGQPVPVYMAQPKDKENLPVVIVISEIFGLHEHITDVVRRFAKQGYLAVAPELFIRQGDPSIYDNIAQIMKEVVSKVPDKQVLGDLDACVAWAKRNGGNPDKIAVAGFCWGGRFAWLYAAHNPSIKAGVAWYGRLTSDTAPSALNPENPIDIAPTLTTPMLGLYGGKDPGISMASIQQMKDALAKGASLSEIVVYPKSGHAFHADYRPSYVADDAKDSWKRCLEWLRAHGVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H114</accession>
    <name>A0A2S9H114_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Patatin-like phospholipase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1672</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93671">
        <property type="protein sequence ID" value="PRC93671"/>
        <property type="gene ID" value="S2091_1672"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002641">
        <property type="entry name" value="PNPLA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01734">
        <property type="entry name" value="Patatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="SSF52151"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PNPLA" evidence="2">
        <location>
            <begin position="1"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="336" mass="37361" checksum="FA036DE9A299A29C" modified="2018-07-18" version="1">MAGGGFHLGYYLGMYAAMRELKKTPDVILASCGGAIAAAIIQALPDDAERKAWLSAPQMYQFWRGLKSKQNATLAGSFIGAMKRRFLGGNAEHIPDLFNDYMFEIPAQLPLPERTSDKAEEDVAVAIVAGKLLYAENEVGQRRGQRKLFSEVIFCDERAAALLNQSQLEAPLSAPMYGDNAVAPQLLTDVTMSIGDAARASIADMFYFRCHSHTSGDYIGGVIDLFPIEVAGCLAENVIMELKAGYDKTYGLPAIRTVLGFDGNQRLHQVFQQPAEMWVDTSDMEEFFLNQRIRQKIIWYKNKIDIVTPPTYAAYVQMIEAQWQFGYQRGLNSVKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H120</accession>
    <name>A0A2S9H120_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">RNA methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1685</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93684">
        <property type="protein sequence ID" value="PRC93684"/>
        <property type="gene ID" value="S2091_1685"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031167">
        <property type="term" value="P:rRNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004398">
        <property type="entry name" value="RNA_MeTrfase_RsmD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004553">
        <property type="entry name" value="CHP00095"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00095">
        <property type="entry name" value="TIGR00095"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="197" mass="22037" checksum="1CFC4E1E94DCE02F" modified="2018-07-18" version="1">MQKKSAPQQVRIIAGIWKRTPLTVLDAPGLRPTPDRVRETVFNWLNFLFQSNWSAIRCLDLYAGSGALGFEAASRGAAQVTLVEAHTPAVLLLEKSRDKLQAQQIQIIRGDAQIVAQKLAAKGDVFDVIFLDPPFHRDLLVSILPICLTLLHPDGVLYLEAEKALTSEDLPECLSNWQVIRCDRAGKVFFHLLQRSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H148</accession>
    <name>A0A2S9H148_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative ATPase involved in cell division</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_1688</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93687">
        <property type="protein sequence ID" value="PRC93687"/>
        <property type="gene ID" value="S2091_1688"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="8" id="KW-0132">Cell division</keyword>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-1278">Translocase</keyword>
    <feature type="domain" description="ABC transporter" evidence="7">
        <location>
            <begin position="2"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="35"/>
            <end position="42"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC93687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="229" mass="24483" checksum="9AFCE0D799DBCB71" modified="2018-07-18" version="1">MIEFKQVSKHFPPGISALSDISFSIGRGELVFLAGPSGAGKSTILKMIAAMERPSSGQVLVNGQDITRLKSASLPYFRRNLGLILQDHALLLDRTVVANVMLPLLISGASRDDALMRATTALEKVNLADKAEAYPLALSGGEQQRVAIARAIVNRPQLILADEPTAYLDRDNATQVMNALQAFQAAGVTCIISSHDEEFLGSASRVIYLNQGKQSQTWQSAAMATSSAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1F8</accession>
    <name>A0A2S9H1F8_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">L-threonine dehydratase</fullName>
            <ecNumber evidence="11">4.3.1.19</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Threonine deaminase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">ilvA</name>
        <name evidence="13" type="ORF">S2091_1406</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10 11">Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>L-threonine = 2-oxobutanoate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:22108"/>
            <dbReference type="ChEBI" id="CHEBI:16763"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
            <dbReference type="EC" id="4.3.1.19"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 11">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 11">Amino-acid biosynthesis; L-isoleucine biosynthesis; 2-oxobutanoate from L-threonine: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 11">Belongs to the serine/threonine dehydratase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.3.1.19" evidence="11"/>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93797">
        <property type="protein sequence ID" value="PRC93797"/>
        <property type="gene ID" value="S2091_1406"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00047">
        <property type="reaction ID" value="UER00054"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004794">
        <property type="term" value="F:L-threonine ammonia-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1020.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="PLP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000634">
        <property type="entry name" value="Ser/Thr_deHydtase_PyrdxlP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001721">
        <property type="entry name" value="TD_ACT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038110">
        <property type="entry name" value="TD_ACT-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005787">
        <property type="entry name" value="Thr_deHydtase_biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="Trypto_synt_PLP_dependent"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00585">
        <property type="entry name" value="Thr_dehydrat_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="SSF53686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01124">
        <property type="entry name" value="ilvA_2Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51672">
        <property type="entry name" value="ACT_LIKE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00165">
        <property type="entry name" value="DEHYDRATASE_SER_THR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9 11" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="5 11" id="KW-0412">Isoleucine biosynthesis</keyword>
    <keyword evidence="8 11 13" id="KW-0456">Lyase</keyword>
    <keyword evidence="7 11" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="ACT-like" evidence="12">
        <location>
            <begin position="349"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="domain" description="ACT-like" evidence="12">
        <location>
            <begin position="443"/>
            <end position="514"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00025527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU362012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PRC93797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="525" mass="58078" checksum="9ADAA3787B0426C7" modified="2018-07-18" version="1">MPDSLASDLAFSMSTDYLKKILTSRVYDVAFETPLEISPTLSSRYGNSIFFKREDMQNVFSFKIRGAYNRMAQLLPAQLKRGVICASAGNHAQGVAFSAAKLNCRARIVMPASTPQIKIDAVIQHGGANVEVILHGDSYSDAYSHALMLEKKHKLTFVHPFDDPDVIAGQGTIGMEILRQHAEPIHAIFVPIGGGGLIAGIAAYVKAVRPEIKIIGVETFDADAMSRSLAAGKRVDLSEVGLFADGTAVKLVGEENFRLAKQYVDEVILVNTDAICAALKDVFQDTRSILEPSGALAVAGAKAYLERAAANKTPLKNQHLITIASGANMNFDRLRFVAERAEIGEAREAVFAVTIPEERGSFKRFCELVGPRNVTEFNYRISDAKAAHIFIGVQVNNRSESSKIAKNFIKHGFPTLDLSEDELAKLHIRHLVGGKSPLAQHELLYRFEFPERPGALMRFLSSMAPNWNISLFHYRNHGADYGRILVGLQVPKNEMREFKKFLANLGYRHWDENNNPVYKLFLAQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1M5</accession>
    <name>A0A2S9H1M5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_1452</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93843">
        <property type="protein sequence ID" value="PRC93843"/>
        <property type="gene ID" value="S2091_1452"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023772">
        <property type="entry name" value="DNA-bd_HTH_TetR-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039536">
        <property type="entry name" value="TetR_C_Proteobacteria"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14246">
        <property type="entry name" value="TetR_C_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01081">
        <property type="entry name" value="HTH_TETR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0678">Repressor</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="3">
        <location>
            <begin position="9"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="2">
        <location>
            <begin position="32"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC93843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="206" mass="22749" checksum="8BB53FF31DBAE4C2" modified="2018-07-18" version="1">MSKPLTLTERKRIAILDAAVAEFRLHGFDATSMDQIALRAEVSKRTVYNHFSSKDELFATMLMQLWNTSASTLDIAYQPNMPLVEQLTKIAAQKMSMLSDGNFLDLARVAIAATIHSPERAQEMIARLGEREENITLWIRSALADGKLKPLDPLFASSQLQGLLKASAFWPQVAMGQPVISAEKQRQIIDGAVHMFLACYGADGAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1P5</accession>
    <name>A0A2S9H1P5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1520</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93911">
        <property type="protein sequence ID" value="PRC93911"/>
        <property type="gene ID" value="S2091_1520"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="182" mass="20539" checksum="0CECAD476E67E737" modified="2018-07-18" version="1">MSDAYRQSALLLHGINKVDRQWILAQLAEEQHVQLSTHLEELTQMGMLANRSLVEGLLSRAAGKSDAPATSTEQPGYALRSAHADVVLHLLNKEPTWLIAAVLSIEAWPWREAIYIGLDASKRDRVKHALRETLPKKLGLALITQLEERLPYAVLELQSRPVELTGFARFGQQISRKMRTWI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1Y4</accession>
    <name>A0A2S9H1Y4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Type III secretion apparatus needle protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1485</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MxiH/PrgI/YscF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93876">
        <property type="protein sequence ID" value="PRC93876"/>
        <property type="gene ID" value="S2091_1485"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030257">
        <property type="term" value="C:type III protein secretion system complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030254">
        <property type="term" value="P:protein secretion by the type III secretion system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021123">
        <property type="entry name" value="T3SS_needle-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037203">
        <property type="entry name" value="T3SS_needle-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011841">
        <property type="entry name" value="T3SS_needle_YscF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09392">
        <property type="entry name" value="T3SS_needle_F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140129">
        <property type="entry name" value="SSF140129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02105">
        <property type="entry name" value="III_needle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0843">Virulence</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="85" mass="9142" checksum="CD20ACC12C1E4F1A" modified="2018-07-18" version="1">MATTAPYPGSGLMVKTAQAFEEGGKELFDREEALRKELAAGGSSDPTKLAEYQALISEISILRNAQSSTVKAFKDMDATIVANFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H236</accession>
    <name>A0A2S9H236_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_1190</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell inner membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the MlaE permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94017">
        <property type="protein sequence ID" value="PRC94017"/>
        <property type="gene ID" value="S2091_1190"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003453">
        <property type="entry name" value="ABC_MlaE_Proteobac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030802">
        <property type="entry name" value="Permease_MalE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30188">
        <property type="entry name" value="PTHR30188"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02405">
        <property type="entry name" value="MlaE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00056">
        <property type="entry name" value="TIGR00056"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="50"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="87"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="148"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="199"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="239"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC94017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="259" mass="28015" checksum="7FBB819989FAE439" modified="2018-07-18" version="1">MIHKLISQLGHGVRVWLAELGLAFRTLWAILASGLGLWKRPRLITTQIHFIGNYSLVIILVSGLFVGFVLAYQGYYTLNRYGSEEALGLLVALSLARELGPVITALLFAGRAGTSLTAEIGLMKAGEQLAAMEMMAVNPLQRVLAPRFIAGIIAMPILATLFTAMGVFGGYLVGVQLIGVDEGAFWSQMQGGVDLWEDIGNGIIKSIVFGFAATFIAIYQGYQAQPTPEGVSRATTRTVVLSSLMVLWLDFVLTALMFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H257</accession>
    <name>A0A2S9H257_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1244</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94071">
        <property type="protein sequence ID" value="PRC94071"/>
        <property type="gene ID" value="S2091_1244"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001845">
        <property type="entry name" value="HTH_ArsR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00778">
        <property type="entry name" value="HTHARSR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00418">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50987">
        <property type="entry name" value="HTH_ARSR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH arsR-type" evidence="1">
        <location>
            <begin position="1"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="107" mass="11734" checksum="9DCC024A5BA06C4A" modified="2018-07-18" version="1">MKIDKIFEALASTPRRKILAYLSESSMTAGEISERFEMSKPSLSKHLKILENADLIQSEKKGQFVHYSLADDNLIGTLHTCLATICPVGGPLVRESAAKAKKNATKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H275</accession>
    <name>A0A2S9H275_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1230</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94057">
        <property type="protein sequence ID" value="PRC94057"/>
        <property type="gene ID" value="S2091_1230"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="124" mass="13993" checksum="F2BD04E591ED7F07" modified="2018-07-18" version="1">MKGKKIKLTNSHHNAMPLEQHSMWLWIALFFRNAFPFIVSIILSACTVTDRHHLPDDWAPVEQGVGSFRQLAGDYAFMGEIGDNSGRKYQLNLFAPSSSWKLIENSTHVKIEVNSGDQLHGLTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H299</accession>
    <name>A0A2S9H299_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1277</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94104">
        <property type="protein sequence ID" value="PRC94104"/>
        <property type="gene ID" value="S2091_1277"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12802">
        <property type="entry name" value="MarR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00598">
        <property type="entry name" value="HTHMARR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00347">
        <property type="entry name" value="HTH_MARR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50995">
        <property type="entry name" value="HTH_MARR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="1">
        <location>
            <begin position="16"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="156" mass="17701" checksum="DBD328F574D2DADF" modified="2018-07-18" version="1">MRELNDNVNKSQLAPEDGVLDLIHNIMHQYRSQQYQVLRDGPHDITHMESKVLSYFEHRPGATQSDLARHTGRDKAQLARLIKGLRDRGLLDGEADEADRRNTKLSLTAIGKSIQHTLFQQAKLLNSKAVKGLNNEEQQQILALLQRMKSNLDAPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2A5</accession>
    <name>A0A2S9H2A5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Outer membrane protein beta-barrel domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_1285</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94112">
        <property type="protein sequence ID" value="PRC94112"/>
        <property type="gene ID" value="S2091_1285"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011250">
        <property type="entry name" value="OMP/PagP_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000498">
        <property type="entry name" value="OmpA-like_TM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01389">
        <property type="entry name" value="OmpA_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56925">
        <property type="entry name" value="SSF56925"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015715168" evidence="2">
        <location>
            <begin position="24"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="domain" description="OmpA_membrane" evidence="3">
        <location>
            <begin position="22"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC94112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="190" mass="19643" checksum="5906D8594892503F" modified="2018-07-18" version="1">MKRNIIATVLAVAGLMLGASAQAQVYVGGTVGESFWNTNCSGTTNCSTNDSGYKMLGGYNINSHWGVEATYFSVGKITANVGEINGEIKGTGADIAGVYRTNFGSSDWGMFAKLGFGSTKGEVIASEGTFTNSITTRTTEPVVGFGVTYAVNESFKLVADIDSRSVKVTVPGTTTSGGVVSLNIGAQVSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2F1</accession>
    <name>A0A2S9H2F1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1338</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94165">
        <property type="protein sequence ID" value="PRC94165"/>
        <property type="gene ID" value="S2091_1338"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="7"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="52"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="180" mass="19881" checksum="6E3929A7E02AC883" modified="2018-07-18" version="1">MTPKSNLRSLVCLSFVVLLHVVIISMWHLRNNFHDITSSELRYLQYVSIAQPRPRPISTPNNSPTVKSQPNKTTKSAVNTESTTAPITEPQAISSTPSNEPRLDLDALRASAVQQELHRTRSPIEKQQEANLKNQSLEARVEDAANKAQRPDCRTAYAGGGLLAPIGIAIDLIRDKGCKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2T7</accession>
    <name>A0A2S9H2T7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_0915</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94294">
        <property type="protein sequence ID" value="PRC94294"/>
        <property type="gene ID" value="S2091_0915"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="3"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="142"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC94294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="215" mass="23471" checksum="98DF4DF153B6D026" modified="2018-07-18" version="1">MIRILIADDHTLMRDGLKQILSTAGDMIVIGEASNGFQVLSSVRSEQCDLLLLDMTMPGRSGVELIKQIKAEKPKLPILVLSMHKEGEYAVRTIRAGAAGYLCKDSASQQLLSAIRAVSSGGRFISPEVAADLAFGLILGDERPLHASLSEREFQIFRRIAAGSSINDIARRLNLSAKTVSTYKTRVMQKMQMTSVAELIRYGLKHGLVDDSSIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2U5</accession>
    <name>A0A2S9H2U5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Fic/DOC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_0922</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94301">
        <property type="protein sequence ID" value="PRC94301"/>
        <property type="gene ID" value="S2091_0922"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003812">
        <property type="entry name" value="Fido"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036597">
        <property type="entry name" value="Fido-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040198">
        <property type="entry name" value="Fido_containing"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13504">
        <property type="entry name" value="PTHR13504"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02661">
        <property type="entry name" value="Fic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140931">
        <property type="entry name" value="SSF140931"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51459">
        <property type="entry name" value="FIDO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fido" evidence="3">
        <location>
            <begin position="113"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="200"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="154"/>
            <end position="157"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="204"/>
            <end position="211"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR640198-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR640198-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC94301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="390" mass="43509" checksum="C6330E59E2D48CF2" modified="2018-07-18" version="1">MYSKANQFEPLIPSPMPQALIDKASEISTSSLRLTSAAHPSARSAIREIVRSLNSYYSNRIEGQGTHPQNIERALRMEFSDKPDIARLQRVALAHIEAERALENRVLGGQSAMSSNFLIASHHALYSRLEVEDRTTVDGHIIVPGEVRTQEVEVGTHVAPTASSLLNFFERMDEVYDRSTGWDLKLISVACEHHRAAWVHPFRDGNGRSVRLQSHCALWNLSDGLWSPSRGIARTVNTYYAKLHNADMPRRGDLDGRGNLTTAGLNEWVEYFLDICLDQVNFMSKMLDLDGMKRRIEALITFRSMHDKGMRAEAILPLFHVFAAGPITRGEFTQISGLGDRTARSLLSRLLATGLLVSDTALGPVRFGLPLDSLQFLFPELYPEAATSPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2X0</accession>
    <name>A0A2S9H2X0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0939</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94318">
        <property type="protein sequence ID" value="PRC94318"/>
        <property type="gene ID" value="S2091_0939"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="223" mass="25151" checksum="2213CAE6D0F69182" modified="2018-07-18" version="1">MQNFKTMATDNALAIGQRVTQTFNKFTAPVKQCHALLVTVSMASLLSGCFINAYPAQHSLCQADALSNWKYNRVQSQLDQKEGRYFFSVRDESWNSKAITSGLLSGVYWIKLDGSPIPRDRGLPVMAYDPAKAYIEVQGKRIPAIPRIWTGAEMPETEVTLPVNFTHKTYFLAFPVTLDKFDTFRVGFGSAWLNGVEIPLPAYESCNTSVHFDWDFSTHHWIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2Y4</accession>
    <name>A0A2S9H2Y4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glyoxalase-like domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0962</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94341">
        <property type="protein sequence ID" value="PRC94341"/>
        <property type="gene ID" value="S2091_0962"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004360">
        <property type="entry name" value="Glyas_Fos-R_dOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00903">
        <property type="entry name" value="Glyoxalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="1"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="133" mass="14116" checksum="76798F85FDDCB3CE" modified="2018-07-18" version="1">MLHHISLGVTNLAKAGAFYDAALAALDFRRVFEDNTAIGYGLYDGKDILCLKLRPNATPPGAGFHLALAAPSRAAVDNFHADALAIGGQDNGAPGLRLHYGADYYAAFLIDPDGYHIEAVCKFSLQQQQAVGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H308</accession>
    <name>A0A2S9H308_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative glycosyl transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0971</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94350">
        <property type="protein sequence ID" value="PRC94350"/>
        <property type="gene ID" value="S2091_0971"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="389" mass="43170" checksum="9AC14D91046E4AF6" modified="2018-07-18" version="1">MIHRQMRVLLFCHDAKGLGHLRRISRIAASLQGDFSCLIMTGMTESHWMVPQECETIKLPSWDGISAVRAKRYNRPRWLHVPIEEAVSIRSRMIASVSEAFQPDAILVDYLPFGINDELRPLLKTTTARKYFIHRGIADSADADMLFGAASQDFGEVYDRIIVTADRRIVDVVKEYKFVPNTAAKTVYVGYVWPPQANHTHGTSEDAPRVVCSCGGGTGGGALLAACIDAARMMPNCNFDVIVGPHGAVPITASLPINCHITMVHKDLTSLHQNAAVVVTHGGYNSVIEAASGGARILVYHLESQTPDSDERIHFEQRLSRYYPVTSVKSLQELTNDIKREVSRAMLEGKAKFVLESDALPRINMLLKSDLMSPKVRQLGEEFELDSQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H325</accession>
    <name>A0A2S9H325_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0978</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94357">
        <property type="protein sequence ID" value="PRC94357"/>
        <property type="gene ID" value="S2091_0978"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="323" mass="36617" checksum="B9FFB2D6965E81AE" modified="2018-07-18" version="1">MKNESQLQSNADSMVQNMYGKYDVQYRLRAPAALCNFATATTAAFMPDQSMPTMDLSRDLVNQVTIPNYGYKNQTKKISPVFSKRQQAALLIKDCQLAFSDVMHAIGNTATKHQKQKIGPAVAPGERYSSELSTEIRTILDRQMPITEFGMRWEPDFQVFYGAGKIFANAGVTNTVPTHDLAHLLIGACGNLEWCPEGEHEEVRLAEYYAVFIENLFDKVYGHMAQGSYKHDTVLNETIAYMRWFVDVHYSPFPIPAEEAYRRFCWNMDVAAIVRLSPLFFALKHVERTITGYRDQIWEMHFNTEDAPLAEQVAAICADGPLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H337</accession>
    <name>A0A2S9H337_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">AMP-binding enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1009</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94388">
        <property type="protein sequence ID" value="PRC94388"/>
        <property type="gene ID" value="S2091_1009"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-binding" evidence="1">
        <location>
            <begin position="141"/>
            <end position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="499" mass="54093" checksum="0B7E53EF9C9CB00C" modified="2018-07-18" version="1">MRFIDLLNNATWTAIYRGVKLDAPSARRLVEQAAQRLQNVQQAAQDALRLATGTVAGQQLTVFCAFTPLETLLCYCIASRLGLLAAVLSPRTLPRFLDDIGPGLVVRLVAPSGHKLPDAAASYGALLLDLSPEAAIEESFEALPPPAQECRLVFNTSGTTGKPKRVLCAESRLIGNAAMVAEYLGLQASDRTLCTFPVHFMYGLSTSLCTLLTGGHIEYCDFLHPGLLATKVAEHGITVLPVIGDWADGLSTRWQQLGYAPQRLLLLNASDRLTQQQARTLLPHATALWNNFGQTESGPRMFAINLSQIDDLDSVTYCGTIAPGFPAFDALELRIAPSDDADGCGVLSYRTPYAMLGYLNDDGSITPPPEWIASGDLFRRAANGAYLWAGRAAHTIKVNGQFVSLRALADDLLTYQTVTGVGYARGKVDELYLFVEAEQPVSDLGAQLRRVVSRTLGGKHSDIRIVPALPRTESGKIDFKQLNMTLAKELNMTLAKEFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3B4</accession>
    <name>A0A2S9H3B4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Yip1 domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_1090</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94469">
        <property type="protein sequence ID" value="PRC94469"/>
        <property type="gene ID" value="S2091_1090"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006977">
        <property type="entry name" value="Yip1_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04893">
        <property type="entry name" value="Yip1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="39"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="94"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="133"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="186"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="220"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="domain" description="Yip1" evidence="6">
        <location>
            <begin position="23"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC94469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="244" mass="26780" checksum="26DF267B62AC2EB4" modified="2018-07-18" version="1">MTTTASTDINHVRSSAFSTLVSMFTEPSRAFAALEKRSMVLLPLLLATLGSALLLLWYYQSVDFAWLQEKLLAGKDMEPAQLEAAKKFMGKSTLIGMSLASTFIGIPVFYALIAVYFLIVAKVSNLTIGFGQWFAFATWSAVPSLLSIPLGVIQILLTQQGQLAPNQLNPLSLNQLFFHIDMNLPWAGLLDNITVTSIWVMVLMVIGFQTWSKKSRATSIAVVVTPCLIIYGVMAVINLMHKAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3H5</accession>
    <name>A0A2S9H3H5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0538</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94535">
        <property type="protein sequence ID" value="PRC94535"/>
        <property type="gene ID" value="S2091_0538"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014917">
        <property type="entry name" value="DUF1800"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08811">
        <property type="entry name" value="DUF1800"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="532" mass="58945" checksum="8B0CC24DCC434736" modified="2018-07-18" version="1">MQLSQLSHQRLLAVGLRRGLLCGMLASLVSCLVSCTNAPTNSAGPSTVVVGTSMSNTKPELLVERLSWGINTNSAQQVNKVGATAYLQQQLQLVPMPNSVTMPQAVQDQIAAMTISQKSLVEIAAELEQLKQASDANGASDDARKNYQQELNRLDKEAQSRAILRALYSPQQLQEQLCWFWFNHFNVFQGKANIRAMLGDYEEQAIRPHVLGHFRELLAATAHHPAMLRYLDNEQNAINHPNENYAREIMELHSMGVDGGYSQRDVQELARILTGVGFSFKNEDPPRLGKFQGQYVHQGLFEFNPRRHDYGDKQFLGHTIKGRGLAEVDEALTLLSRHPATAHFVSKKLALFFVGETPSPALVDSMAKTFLATDGDIKAVLSTLFASAEFNNSLGKQFKDPQHYVFSALRLAYDDKPILNTNPVIYWLSRLGQPRYGKLTPDGYPLTATAWDSPGQMTTRFEIAKAIGNGSAGLFKSDNGNESAGFPKLSNALYFNYLQSTLGPNTLKSLEQANSPQEWNTLLLAAPEMMVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3L1</accession>
    <name>A0A2S9H3L1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Metal-dependent hydrolases of the beta-lactamase superfamily II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0577</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94574">
        <property type="protein sequence ID" value="PRC94574"/>
        <property type="gene ID" value="S2091_0577"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07713">
        <property type="entry name" value="DHPS-like_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041712">
        <property type="entry name" value="DHPS-like_MBL-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015429558" evidence="1">
        <location>
            <begin position="24"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="domain" description="Lactamase_B" evidence="2">
        <location>
            <begin position="47"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="303" mass="33347" checksum="FA2AFD969CFD2BB3" modified="2018-07-18" version="1">MKNCRLILVSIAALLFFSVTAHAKESPARVTIIYDAFGKPSNLERGWGYSALVEYGGKRILFDTGGQYKAFANNVRKLHIDLKNLDFVVISHRHGDHTAGLNYVLQQNPNVKIYAPLERGSFGAPVTANSTIGKSMLRVVDGIPGDLHYFNGYRADKYPIDSPWPDANFNLVDTQLEVMPGIFLFKTVSENKGTLELNELSMAIKTPSGLVVVVGCSHPGIEKILAVASQIDPKIYTIVGGLHLIDKSDQLVTQTVDNFKNKWMIERVAAGHCTGEFAQTELERVFGIRHDHSGLGEVIALPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3Y5</accession>
    <name>A0A2S9H3Y5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_0698</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPF0719 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94695">
        <property type="protein sequence ID" value="PRC94695"/>
        <property type="gene ID" value="S2091_0698"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007140">
        <property type="entry name" value="DUF350"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03994">
        <property type="entry name" value="DUF350"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="40"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="72"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="106"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC94695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="128" mass="13460" checksum="E879169916DF4698" modified="2018-07-18" version="1">MAAITNYALHLLTASALLAVFFMVYTYVTTIDEVLLIRQGNNAAMLSMSGALIGFSLTIGSSLLHTSNYLEFMAWAAGAMVVQVLAYAVTVRLLHISKEHIESGNTAFGGLMGAISLSIGAINAACIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H414</accession>
    <name>A0A2S9H414_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Malonate decarboxylase holo-[acyl-carrier-protein] synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0728</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94725">
        <property type="protein sequence ID" value="PRC94725"/>
        <property type="gene ID" value="S2091_0728"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017557">
        <property type="entry name" value="Holo-ACP_synthase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10620">
        <property type="entry name" value="MdcG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03135">
        <property type="entry name" value="malonate_mdcG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="218" mass="24072" checksum="A7501E3A7584DC59" modified="2018-07-18" version="1">MKTYRPHDLLFIRLAHQQRRDIFNTPLPSWVNPHWPVVVRRAPPSAGGVWLPVGLRGTARFERLPAMMRSDVVQDSVSPESLLAEHDWQRHLQGQDFPCVRALHSIAGALNALGLSCGPTGSVGFALATGASILRIDSDLDLLVRAPNTISNQQSDKLQHIKELVVSHQCRIDIQIDTGNGGFAFDEWARNPKKVLLKTATGPILTATPWISPMELDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H435</accession>
    <name>A0A2S9H435_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0740</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94737">
        <property type="protein sequence ID" value="PRC94737"/>
        <property type="gene ID" value="S2091_0740"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015492443" evidence="1">
        <location>
            <begin position="26"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="175" mass="19460" checksum="068352FE39DB5AD3" modified="2018-07-18" version="1">MQFKNNWYVLSSIVVLAIGTFDAQAQTNHSFLKTDSLMCDGWTVSIRSICSASVNGAVPHCTQKLTFKTAIGDDYSVNYEPDPVQHKDEPFVSQLSCNPGENKHYVVAHSGNFANCSTCEWIDVFTLHGDLIGSTPSIVRALKLPRKKLSRSFESLLGEPLKNELISIDRTYSEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H455</accession>
    <name>A0A2S9H455_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0716</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94713">
        <property type="protein sequence ID" value="PRC94713"/>
        <property type="gene ID" value="S2091_0716"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010696">
        <property type="entry name" value="DUF1272"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06906">
        <property type="entry name" value="DUF1272"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="102" mass="11432" checksum="5992EBBAEF15FBD7" modified="2018-07-18" version="1">MLELRPTCEHCKTALPPNATTARICTFECTFCADCVENVLNNVCPNCGGGFEKRPVRPSVNWKNDNYLGRYPAKDEIKYKPVDQVAHSEFSSAIKDIPPEAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H466</accession>
    <name>A0A2S9H466_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cytochrome c-type biogenesis protein CcsB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_0772</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94769">
        <property type="protein sequence ID" value="PRC94769"/>
        <property type="gene ID" value="S2091_0772"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017004">
        <property type="term" value="P:cytochrome complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002541">
        <property type="entry name" value="Cyt_c_assembly"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017562">
        <property type="entry name" value="Cyt_c_biogenesis_CcsA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045062">
        <property type="entry name" value="Cyt_c_biogenesis_CcsA/CcmC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30071">
        <property type="entry name" value="PTHR30071"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01578">
        <property type="entry name" value="Cytochrom_C_asm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03144">
        <property type="entry name" value="cytochr_II_ccsB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0201">Cytochrome c-type biogenesis</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="45"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="70"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="108"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="132"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="175"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="205"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="249"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="288"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="322"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="351"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrom_C_asm" evidence="7">
        <location>
            <begin position="172"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC94769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="381" mass="43264" checksum="71D85AFCB87593EB" modified="2018-07-18" version="1">MEMTQNYQPYQGFFKRLTVLDWLYAVALLTASGVALLRFSHHMDYYEQIVLVLAAPTFALLGWNWKSVRWLIAVLALLSWCAISQYGGSLELANSKFLLKYLLSSQSAILWMSFLFFLSTIFYWGGLIARSALGYSIGSMLCWSSVIMGFTGMMVRWYESYLLGADIGHIPVSNLYEVFILFAMITALFYLYYEHQYKTRQLGPFVMLVISAAVGFLLWYTVKRDAAEIQPLVPALQSWWMKIHVPANFIGYGTFSLAAMVGVAYLVKSKGWLVDRLPALEVLDDVMYKAITVGFAFFTIATILGALWAADAWGGYWSWDPKETWALIVWLNYAAWLHMRLMKGLRGQVAAWWAVIGLLVTTFAFLGVNMFLSGLHSYGTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4L0</accession>
    <name>A0A2S9H4L0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">HlyD family secretion protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0078</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94883">
        <property type="protein sequence ID" value="PRC94883"/>
        <property type="gene ID" value="S2091_0078"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="SSF51230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="31"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="137"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="446" mass="49029" checksum="11FF3F16C668FE03" modified="2018-07-18" version="1">MSMTEQTLFRSEVFTAQDDAWLGALHFAQPLSAWLIAGLALMVTAALIAFISVGTITKKARATGIIVPSSGSLTITAHNAGVLIHRHVEEGQQVHAGQTLFELSTERQGASGEITALVAQQLASRELSLATEQRLRINQDADKKRVLQERLQNLAAEATQLEHELILADRRQNLAQQSLHQFETLQQSGYVSLAQARQKQEELIDIDSRLSSLKRSKMQLQANQISLNSELTQLATTLASDLSQIKRAQASLQQEMLENQNRKTSFITAPQAGLITTITYQAGQAVSGGQSLATLIPVESISADSIISNKESSVSQLEAHLYLPSRTAGFVAVGQTVQIRYQAYPYQKFGLQKGKVTDVSTTPFAPNELPINLASTILSNAQQNMWGVNTNEALYRIKVQLNKQTIAAYGQEQFLKPGMTLEADVVQDSRKIWEWIVEPVLAVTQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4R0</accession>
    <name>A0A2S9H4R0_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Histidine kinase</fullName>
            <ecNumber evidence="4">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">S2091_0126</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Cell membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="4"/>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94931">
        <property type="protein sequence ID" value="PRC94931"/>
        <property type="gene ID" value="S2091_0126"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00088">
        <property type="entry name" value="HPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036641">
        <property type="entry name" value="HPT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013656">
        <property type="entry name" value="PAS_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013767">
        <property type="entry name" value="PAS_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013655">
        <property type="entry name" value="PAS_fold_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029151">
        <property type="entry name" value="Sensor-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008207">
        <property type="entry name" value="Sig_transdc_His_kin_Hpt_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01627">
        <property type="entry name" value="Hpt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00989">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08447">
        <property type="entry name" value="PAS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08448">
        <property type="entry name" value="PAS_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103190">
        <property type="entry name" value="SSF103190"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47226">
        <property type="entry name" value="SSF47226"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50894">
        <property type="entry name" value="HPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="13" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 11" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="332"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="16">
        <location>
            <begin position="359"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="17">
        <location>
            <begin position="431"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="16">
        <location>
            <begin position="511"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="17">
        <location>
            <begin position="593"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="17">
        <location>
            <begin position="718"/>
            <end position="769"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="17">
        <location>
            <begin position="851"/>
            <end position="903"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="17">
        <location>
            <begin position="981"/>
            <end position="1033"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="14">
        <location>
            <begin position="1051"/>
            <end position="1272"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="15">
        <location>
            <begin position="1292"/>
            <end position="1415"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="15">
        <location>
            <begin position="1439"/>
            <end position="1557"/>
        </location>
    </feature>
    <feature type="domain" description="HPt" evidence="18">
        <location>
            <begin position="1594"/>
            <end position="1691"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="268"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="11">
        <location>
            <position position="1345"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="11">
        <location>
            <position position="1490"/>
        </location>
    </feature>
    <feature type="modified residue" description="Phosphohistidine" evidence="10">
        <location>
            <position position="1633"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="PRC94931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="1777" mass="199220" checksum="63E88BC3A40C365B" modified="2018-07-18" version="1">MKNSLRELGRPIVICTLLIFIALISTTLFIVGQVERERTINAMKSRMLASSEIRKARLTEHINQLRHDVQFLSKVPPVQGMIRSIGHGGVDIQENTPLSLWQKRLQTIFLEFIKANPELTKLRFIGVANDGMELVRIERKQGKIFVVTQDQLQAKGDRYFFISASKLKLNQSYLSDIDLNRERGKIDEPVVRTLRAATPVFAENGEIFGIVILNRNVQSDFAELESSSTANFKIYLTNSSGDYLVNPDQQHTFGFDYGNQWRWQNDFHFDSSDQQHPSGPQSFLTSDGSTTHVVQTQIPLDENDPNRFLTLAVTLPDKTIAQAVMNAQLNSLFVILGASLLASGAMYFYWWQKRHLDKKQSEMAAIVESSHDAIIGKTLEGVVTSWNTGAEEMFGYSSKEAVHKRLVDLIVPDDRRGEEVLILRKLSNGERITDFDSIRHRKDGTLLDVSVTVSPIRSLSGKVIGAAKTVRDISQKKKDEESIRELNRTLEIQVVERTAKIRSYSALQHAILNNASYAMIATDTNGLITVFNPSAERMLGYTADEIVGKKNPEIFHDMAEVIERANAFSEELGEEIKPGFNVFVAKSIRGLPNEHEWTYVRKDGSRLSVQLSATALRDDNGNIIGYLGIVSDLTERQIAENALQAQYRFLNTLADNIPGLVAYWDRDLCCRFSNRVYYEWFGKTSEEMRGIHLRTLLGETLYAKNEHHINAAFAGQVQLFERTMTKPDGSLLYTWAHYIPDIDNGAVRGLIVLVSDVTELKVAQLNLEELNSRLKIRTNDLERTGQIAGAGAWSVDLIGKKINWSRQTALIHEVPDGYEPTVEKSIQFYTKESQHVIQSILDKALKTHQPWDIELPIITAKGKHRWTRSVGEVELNKNGDPIKLFGAIQDITERRTASEALTAVRDQLLMAAKVAGLGIWGWQLSDDSLLWNDLMFELYDQPKSLNRNGLNYEHWRSRVHQEDVEATVKCLNDAVEGHGIYDPIFRVVHLDGEVRYLKAAAYIERDDSGKALRVTGINMDITDQLLLESSLRQAKDSADIANRAKSEFLANMSHEIRTPMNAILGMLQLLQQTELDRRQVDYVSKTESAAKALLGILNDILDFSKVEAGKMELDPHPFSIDKLLRDVAVILSANVGNKDVEVLFEVDPTIPKWIISDDLRLQQILINLAGNAIKFTEHGEIVLSVKLVTSDESGLTIDFSVRDTGIGISPEQCERIFEGFSQAEASTARRFGGSGLGLAICQRLVRLMGGTLEVNSTVNVGSTFHFTMCCKRSEQVDVPSEKRLVVDTKTLHCLVVEDNSSARQILAEMLRSFRWEVDTADSGLTAIDMVEKRNKKNPYDVIFVDWRMPGMDGWETSKHIREKLSGLSATIIVMVTAHSRELIAQRKTQMPSLLDGFLVKPVTASMLYDAVADSRANNGQVVPVELRQPIQQQRLAGVRILVVEDNATNQQVARELLSNDGALVVVVDDGQAGIDALRFAEPRFDVVLMDVQMPNMDGYTATKIIRTELGETTLPIIAITANAMSSDRDAAFAAGMTDHVGKPFDLSQLISVILKHIKHDATMLILPNEELEEHESLYLQDFNADSALIRLGGNSKTYQAALKGFIREVSDSKLHYEALKKNQRRDDIRRMFHTIKGLAATVGANRLSAIAESEENYLNDPSNTGPLKELDSFWLVADSALENAKRHLIAAVDVEVTTSVYDQVDLLTLREELGRLQVQLQSSDFDAEQKYDQLHRSCGAIFPVEYKKIGECIELLKFADAALICAELLNEIDSLIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4S0</accession>
    <name>A0A2S9H4S0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0071</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94876">
        <property type="protein sequence ID" value="PRC94876"/>
        <property type="gene ID" value="S2091_0071"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2310.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035093">
        <property type="entry name" value="RelE/ParE_toxin_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="109" mass="12788" checksum="E27002A26387CF9B" modified="2018-07-18" version="1">MIYSVNVLGAARLDYREIRKLVRMKFGENTWLETETHFKKMLNQIGAMPHAGAMPDEIAELGLTHYRQRLVGQTRIIYQITDRAVYIHLFVDSSRDFSTMLNQRLMQAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4X6</accession>
    <name>A0A2S9H4X6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Angiotensin-converting enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0213</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95018">
        <property type="protein sequence ID" value="PRC95018"/>
        <property type="gene ID" value="S2091_0213"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008241">
        <property type="term" value="F:peptidyl-dipeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06461">
        <property type="entry name" value="M2_ACE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001548">
        <property type="entry name" value="Peptidase_M2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10514">
        <property type="entry name" value="PTHR10514"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01401">
        <property type="entry name" value="Peptidase_M2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00791">
        <property type="entry name" value="PEPDIPTASEA"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015548249" evidence="1">
        <location>
            <begin position="21"/>
            <end position="605"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC95018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="605" mass="68597" checksum="92F6A7FC3815C490" modified="2018-07-18" version="1">MKLNPLVLACSVLITQVSWAQTAAPSTGTPTTAEAEQFVHDAEAKLEAAVIRAQRAEWIYENFITDDTEAATAQESEALLAISGELALQARRYNGVLMSEASKRKLAQMQLNLMLSDPAERAAYARIAASMSGSYGKAKYCPKKDDPKSCLALGELEHIMATSRDPALLKEVWLGWHSLSPSYKDDYAKYVALSNKGAVNMGYADTGALWRSNYEMTPKQFEFEMERLWQQVKPLYDSLYTYTRHQLQKTYGEKEVPSTGPIPAHLFGNMWSQTWDNLYPILKPEGLSSSYDLSEVLKERKVTPTQMAGYAERFYTSLGMEKLPETFWKRSLLSKPKDREVVCHASAWDIDARQDVRIKMCITPTAEDFTTIHHELGHVYYFLAYRDQDPMFHNGANDGFHEAIGDTIALSVTPEYLKKIGLRETLPTKDQEIGTLLNRALEKVAFLPFGYLVDKWRWEVYSGKVTPENYDKAWWELREQYQGISRPAPMEANGFDAGAKFHVASDTPYARYFLADILQFQFHRALCKEAGYVGPLNRCSIFENKQAGEKFQAMLKMGSSKPWPEALKTMTGSDRIDATAILDYFAPLKVWLDEQNALYEKSAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H555</accession>
    <name>A0A2S9H555_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HDIG: uncharacterized domain HDIG</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0317</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95122">
        <property type="protein sequence ID" value="PRC95122"/>
        <property type="gene ID" value="S2091_0317"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008081">
        <property type="term" value="F:phosphoric diester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021812">
        <property type="entry name" value="DUF3391"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037522">
        <property type="entry name" value="HD_GYP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006675">
        <property type="entry name" value="HDIG_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11871">
        <property type="entry name" value="DUF3391"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00277">
        <property type="entry name" value="HDIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51832">
        <property type="entry name" value="HD_GYP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HD-GYP" evidence="1">
        <location>
            <begin position="151"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC95122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="428" mass="47708" checksum="C57873FACCBE22BB" modified="2018-07-18" version="1">MNSEVKTMTISVDQLCVGLYVHLDIGWLEHSFARNSFRIKNAEQIASIRKLGLKTIRIEPARCEARPLPPPPVVAPAAAPVVEQPSAEELAMIQAKKERVERLMAEREAIARCEKEYLKAANTLKNISRNLFSRPEAAYEDADQLIQQMLDSLLAERDIAIHLMNDKIAGEEAYYHSLNVSILAMMVAKEMALPPADIKILGMGCLFHDTGKVEIPDRIVHNKFELTKAEQNLLQLHCNYGVAIAEKIGLPKGAIDIIMQHHEYADGSGYPGHLIADKISLLARIVCVINTYDNHCNRPNPADSLTPYEALVHMFAHQRKLFDPIPLNIFIRCMGVYPPGTVVKLSDGTFGMVVSVNAGKPLRPCVLIYDPSVPKNEAIILDLNKESELEVSASLRPAVLAPAVYAYLSPRKHMTYYFDTQNTQAPKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H556</accession>
    <name>A0A2S9H556_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Response regulator receiver domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0266</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95071">
        <property type="protein sequence ID" value="PRC95071"/>
        <property type="gene ID" value="S2091_0266"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="11"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC95071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="131" mass="14702" checksum="F53E831A1A8A82C9" modified="2018-07-18" version="1">MTMLAETQNLKIMVIDDSSTIRRSAEIFLGQVGYQVILAEDGFDALAKINDYHPDLIFCDILMPRLDGYQTCALIKKSAKFRNTPVIMLSSKDGLFDRARGSIVGSNEYLTKPFTKDSLLKTVRNYTAKAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H583</accession>
    <name>A0A2S9H583_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative 3-oxoacyl-(Acyl-carrier-protein) reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0339</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95144">
        <property type="protein sequence ID" value="PRC95144"/>
        <property type="gene ID" value="S2091_0339"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011285">
        <property type="entry name" value="FabG-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01831">
        <property type="entry name" value="fabG_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC95144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="241" mass="25604" checksum="5A05875FFD0C7C26" modified="2018-07-18" version="1">MNKSVLVTGSSRGIGKAIALRLAADGYDIVIHCRSMRDEADQVAQTIAAMGRACRVLQFDISDRDTTATTLLADVEQHGCYYGVVCNAGVARDNAFPAMSGEDWDIVLQTNLDGFYNVLNPLIMPMVRRKKPARIVTLASVSGLIGNRGQVNYSAAKAGIIGATKALAIELASRAITVNCVAPGLIDTDMVSGVPMEEALKMIPARRIGKPEEVAAVVSFLMNDDAAYVTRQVISVNGGMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5E6</accession>
    <name>A0A2S9H5E6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Beta-ketoacyl synthase, N-terminal domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0356</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95161">
        <property type="protein sequence ID" value="PRC95161"/>
        <property type="gene ID" value="S2091_0356"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13723">
        <property type="entry name" value="Ketoacyl-synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ketoacyl_synth_N" evidence="1">
        <location>
            <begin position="26"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC95161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="255" mass="27952" checksum="C4B1B0E35457550F" modified="2018-07-18" version="1">MQTNKVQFSVAAHAAWAPNLVTNQEWNDWAEAPFVIQAGAEPSVLKMPSMLRRRAGFLGKMALEVAYQCLDGRTSDQHTIPTVFCSRHGDVSRAMELLANVVQNEPLSPTSFGLAVHNASAGLFSIARSDQANHIALAAGQCTIEHGVIEACSLLADGAPSVLLVVFDNCLPSLLSQFEDCEEQPHAWAWLMVPAVSAVSAERNVIQLSWKAVEPNLPEQNAMPASLEVLKFYLRGDPVFERTAERRLWSWSRSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5M2</accession>
    <name>A0A2S9H5M2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0480</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95285">
        <property type="protein sequence ID" value="PRC95285"/>
        <property type="gene ID" value="S2091_0480"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC95285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="36" mass="4399" checksum="5060C26944602DBC" modified="2018-07-18" version="1">MKLTNYQINLFDYLYTVENMIFTHRKTIGYAKNIKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5M9</accession>
    <name>A0A2S9H5M9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0428</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95233">
        <property type="protein sequence ID" value="PRC95233"/>
        <property type="gene ID" value="S2091_0428"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015568452" evidence="2">
        <location>
            <begin position="25"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC95233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="62" mass="6628" checksum="CAA732146E3129FA" modified="2018-07-18" version="1">MKKLIALFAALCVAATFSMGSAFAQAPAHATHHAKHAKHAKTSAHKKAHKKAHKKSAKKHHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5S1</accession>
    <name>A0A2S9H5S1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0421</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95226">
        <property type="protein sequence ID" value="PRC95226"/>
        <property type="gene ID" value="S2091_0421"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC95226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="71" mass="7420" checksum="4318EE6E79B20FB2" modified="2018-07-18" version="1">MGIAVEVAVEVAVEVAVEVAVEVAVEVAVEVAVEVAVEVVFEVAVVFDFELPPILTLPVNLAKNGSERFAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSB7</accession>
    <name>A0A2S9GSB7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Prepilin-type N-terminal cleavage/methylation domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_4675</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000044">
        <property type="protein sequence ID" value="PRC90607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90607">
        <property type="protein sequence ID" value="PRC90607"/>
        <property type="gene ID" value="S2091_4675"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015627">
        <property type="term" value="C:type II protein secretion system complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015628">
        <property type="term" value="P:protein secretion by the type II secretion system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000983">
        <property type="entry name" value="Bac_GSPG_pilin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013545">
        <property type="entry name" value="T2SS_protein-GspG_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08334">
        <property type="entry name" value="T2SSG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00813">
        <property type="entry name" value="BCTERIALGSPG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="domain" description="T2SSG" evidence="2">
        <location>
            <begin position="37"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC90607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="79" mass="8713" checksum="4B3866921011850F" modified="2018-07-18" version="1">MYKITTKNRKNTGFTLLELLVVIVIIGLLAAYVGPKYFAQLGKSEVTIAKSQIEAFDKAVDTFRLDVGRFPTSEEGLAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSC0</accession>
    <name>A0A2S9GSC0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4702</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000046">
        <property type="protein sequence ID" value="PRC90595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90595">
        <property type="protein sequence ID" value="PRC90595"/>
        <property type="gene ID" value="S2091_4702"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC90595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="54" mass="5646" checksum="F02CB9CB75093FE5" modified="2018-07-18" version="1">MLMSAADVAFMKGEAAARPGDGPDMAFVRASEHGYIVPGVQQTAFMQGFLQAIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSG0</accession>
    <name>A0A2S9GSG0_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 11">tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10 11">Glucose-inhibited division protein A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">mnmG</name>
        <name evidence="11" type="synonym">gidA</name>
        <name evidence="14" type="ORF">S2091_4643</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 11">NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 11">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="9 11">Homodimer. Heterotetramer of two MnmE and two MnmG subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the MnmG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000041">
        <property type="protein sequence ID" value="PRC90635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90635">
        <property type="protein sequence ID" value="PRC90635"/>
        <property type="gene ID" value="S2091_4643"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002098">
        <property type="term" value="P:tRNA wobble uridine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.570">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00129">
        <property type="entry name" value="MnmG_GidA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004416">
        <property type="entry name" value="MnmG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002218">
        <property type="entry name" value="MnmG-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020595">
        <property type="entry name" value="MnmG-rel_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026904">
        <property type="entry name" value="MnmG_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044920">
        <property type="entry name" value="MnmG_C_subdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040131">
        <property type="entry name" value="MnmG_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11806">
        <property type="entry name" value="PTHR11806"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11806:SF0">
        <property type="entry name" value="PTHR11806:SF0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01134">
        <property type="entry name" value="GIDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13932">
        <property type="entry name" value="GIDA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00136">
        <property type="entry name" value="gidA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01280">
        <property type="entry name" value="GIDA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01281">
        <property type="entry name" value="GIDA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 11" id="KW-0274">FAD</keyword>
    <keyword evidence="5 11" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8 11" id="KW-0520">NAD</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="GIDA" evidence="12">
        <location>
            <begin position="8"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="domain" description="GIDA_C" evidence="13">
        <location>
            <begin position="402"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="13"/>
            <end position="18"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="274"/>
            <end position="288"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00031800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF13932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="PRC90635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="645" mass="71041" checksum="4D048737A1CE273D" modified="2018-07-18" version="1">MFYPKEFDVIIVGGGHAGTEAALASARMGQSTLLLTHNIETLGQMSCNPSIGGIGKGHLVKEVDAMGGAMAIATDEAGIQFRILNSSKGPAVRATRAQADRILYKQAIRSRLENQPNLYLFQQAVDDLLIEGDRVVGAVTQVGIKFKARAVVLTAGTFLDGKIHVGLSQYAAGRAGDPPAISLSSRLKELSLPQGRLKTGTPPRIDGRSIDFSVMQEQPGDLDPVPVFSVLGNAKMHPRQVPCWITHTNQQTHDIIRTGLDRSPMYTGVIEGVGPRYCPSIEDKIHRFSGKESHQIFLEPEGLTTNEFYPNGISTSLPFDIQLALVRSMNGMENAYILRPGYAIEYDYFDPRGLKASLETRQIQGLFFAGQINGTTGYEEAAAQGMLAGLNAALFTQQKDAWVPGRSEAYLGVLVDDLITKGVQEPYRMFTSRAEFRLSLREDNADMRLTEIGRKLGCVSDLQWAAFEIKRESVARELERLKSTWVNPRLIADAEAERVVGKALEREYSLVDLLRRPQVSYESLMTLRGVDGQDVAGPAVQDAAVKEQVEIHVKYEGYIDRQAKEVQKHAHFENLPMPDNFDYLDVSGLSIEVKQKLNQQKPETLGQCSRISGVTPAAISLLLVHLKKRGFKEFSQTPTLVEGSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSM8</accession>
    <name>A0A2S9GSM8_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Toxin CcdB</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Cytotoxic protein CcdB</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Protein LetD</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_4606</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CcdB toxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000038">
        <property type="protein sequence ID" value="PRC90713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90713">
        <property type="protein sequence ID" value="PRC90713"/>
        <property type="gene ID" value="S2091_4606"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008657">
        <property type="term" value="F:DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006276">
        <property type="term" value="P:plasmid maintenance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002712">
        <property type="entry name" value="CcdB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011067">
        <property type="entry name" value="Plasmid_toxin/cell-grow_inhib"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01845">
        <property type="entry name" value="CcdB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00015075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00029628"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00033135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC90713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="83" mass="9184" checksum="BF2952683C5ABBBA" modified="2018-07-18" version="1">MHNNIVSGLISRVVIPLRPLQQFQALNIPIDVFPLISVNGNDYFLDTPQLGAIDSGELKNIVSSAQIYQFEIQNAIDRVLGGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSQ1</accession>
    <name>A0A2S9GSQ1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_4573</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000037">
        <property type="protein sequence ID" value="PRC90747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90747">
        <property type="protein sequence ID" value="PRC90747"/>
        <property type="gene ID" value="S2091_4573"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001845">
        <property type="entry name" value="HTH_ArsR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00418">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50987">
        <property type="entry name" value="HTH_ARSR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH arsR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="78"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC90747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="107" mass="12346" checksum="DB80537DFB1F4D25" modified="2018-07-18" version="1">MALAHPARRAILSQLGKGDATVGELAQPFDMSLPAITKHLKVLERARLISRSKNAQWRPCRLENVPLKAASGWIEEQRKIWESRLDRLEDYLHNMEKMEERKNDDNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GT04</accession>
    <name>A0A2S9GT04_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF3857 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_4489</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000035">
        <property type="protein sequence ID" value="PRC90826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90826">
        <property type="protein sequence ID" value="PRC90826"/>
        <property type="gene ID" value="S2091_4489"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024618">
        <property type="entry name" value="DUF3857"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12969">
        <property type="entry name" value="DUF3857"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="SSF54001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015400679" description="DUF3857 domain-containing protein" evidence="2">
        <location>
            <begin position="25"/>
            <end position="795"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="666"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="696"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="721"/>
            <end position="742"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="776"/>
            <end position="793"/>
        </location>
    </feature>
    <feature type="domain" description="DUF3857" evidence="3">
        <location>
            <begin position="75"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC90826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="795" mass="89576" checksum="972103EABDBE25A5" modified="2018-07-18" version="1">MRKLPDILRLIGCFLLFSVATTNAATREYQIGPAPEWVIPVSFNTSTNRENNDNDSSLIYLLSDQQTRVEHVGKTTYFHYAKKATASNGLEKIASINIVFDPSYQNLVLNVVNIIRNGQVIKKTDSVAIHVLQRETELDYLIYDGSKTVNVVVDDVRVGDIVEYAYSLSGMNPVFQNKASGGGDLQWAVPIERVFFRLMVPTDRHFTIKSHESKLQSVMTERNGYRDYQWDVANMPGLKLESDTPSWYEPYGSIQWSEFPDWLAVQQWAKPLYRTPDVLPAELSKEVSHIKQTATSQGDRMLAALHFVQREIRYLGIEVGPGSHAPNAPALVMQRRFGDCKDKTLLTLTLLKALGIEAYPALVNTTMGPSLTDWSPTPNLFNHVLVRAKVDGNIYWIDPTRSLQQGDLAHLYQPDYGHALVLDNVSNKLTVMNSSVSTKKIVNAEFDSTAGLDKPVKLVVTTTDYGKHADELRNNINSHSKNELEKNYLNYYARYYPTIKSTDSIEFREDIANNTVTTIESYTIPNFWVLQENKIKRDATIHIPDVRLFLTAPKDINRTAPIRVSFPEDVSVTTELKLPSKWNIDDSQSNIDDPAFEYSNKTWMSDNGRRLHLSDQYRALTDHVDAQDIPAYAANLNKAYDSVGFTLNYSGTNTPVKKAHFSHNDWKYLIIILMLIIWSWMIMLQQTSPPENRLSDRSLVSCTVVASGSFIPFLLSSDVHWLLLLGALGICTALIMLAKAVNSAPQSHWLSRYAGGYTQTVHSTFSARLLPILKKIPAVIGWITIGVVIYRGVVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GT78</accession>
    <name>A0A2S9GT78_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acetyltransferase (GNAT) family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4408</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000033">
        <property type="protein sequence ID" value="PRC90915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90915">
        <property type="protein sequence ID" value="PRC90915"/>
        <property type="gene ID" value="S2091_4408"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="88"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="217" mass="23604" checksum="806C1BEDA6486F09" modified="2018-07-18" version="1">MNVDHNLKVHKEIVKAWVLGWTLSRGTAPPVQIENAYRVDVGLPDHCTRYVLPQLDPNFLHDLTEQLLEPGTWLKICAPSALVAPLLSQAWSIKDTGHMMIRALRVMARPAPPDYLLVTTSDGAVLDVKMLDQAGEIAATGRIAVIQPFAVIDQVVTSPSHQRRGLGSFVMEVLCQHAAEQGAQTGVLVATDEGMALYRSLGWALHSVVTSAVIEMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTG3</accession>
    <name>A0A2S9GTG3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">FHA domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4299</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000031">
        <property type="protein sequence ID" value="PRC91003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91003">
        <property type="protein sequence ID" value="PRC91003"/>
        <property type="gene ID" value="S2091_4299"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00060">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00240">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SSF49879"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FHA" evidence="1">
        <location>
            <begin position="23"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="202" mass="21900" checksum="73513B61245CCDEF" modified="2018-07-18" version="1">MAKISVTLEGAILQEIPINKVKITIGRRPSNDVVLNHLAISGEHAVIETHSNDSFLEDLNSTNGTQVNGQPVKRHFLQNGDVISLAKYKLRFEMDGMHHVINSQFPDPNPVPGASVKHAFVKVLNGSNAGRQLVLSKELTTLGTPGVQVATITRTNNTYFLTHVEGAQSTLVNDAGIGNKVRELKQGDVIDLSGTRLMFQTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTG9</accession>
    <name>A0A2S9GTG9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Prepilin-type N-terminal cleavage/methylation domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4315</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000031">
        <property type="protein sequence ID" value="PRC91019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91019">
        <property type="protein sequence ID" value="PRC91019"/>
        <property type="gene ID" value="S2091_4315"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="194" mass="20377" checksum="BA69AD1AE1EC2F3E" modified="2018-07-18" version="1">MFIKLRSTKHQQGFSLLEVLISILIIAIGLLGLSKMQALSIANAQVSGARGLVALQSLSLAAIMHGDKTYWQTGATATAAATTPPCNSACSLSGTTLPSSFGTVASSGCSSTTTACTPIQIAAYDITTWMAQMNPQVPAYKTTITCANTNSATGTFPTTCIIETTWTERQLGMNNNAVNDSSSTTQSYYLYVQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTQ0</accession>
    <name>A0A2S9GTQ0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4256</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000030">
        <property type="protein sequence ID" value="PRC91068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91068">
        <property type="protein sequence ID" value="PRC91068"/>
        <property type="gene ID" value="S2091_4256"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="53" mass="6028" checksum="3AD7A05F444031F2" modified="2018-07-18" version="1">MKKSNVTAMYRRLIASIGKERAVTTKDLKPAWFLSEAISTIAIYDTLPSVFFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTQ7</accession>
    <name>A0A2S9GTQ7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">CheB methylesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_4196</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000029">
        <property type="protein sequence ID" value="PRC91100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91100">
        <property type="protein sequence ID" value="PRC91100"/>
        <property type="gene ID" value="S2091_4196"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000156">
        <property type="term" value="F:phosphorelay response regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008984">
        <property type="term" value="F:protein-glutamate methylesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035909">
        <property type="entry name" value="CheB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022642">
        <property type="entry name" value="CheR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000780">
        <property type="entry name" value="CheR_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022641">
        <property type="entry name" value="CheR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000673">
        <property type="entry name" value="Sig_transdc_resp-reg_Me-estase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01339">
        <property type="entry name" value="CheB_methylest"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01739">
        <property type="entry name" value="CheR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03705">
        <property type="entry name" value="CheR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00996">
        <property type="entry name" value="CHERMTFRASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00138">
        <property type="entry name" value="MeTrc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52738">
        <property type="entry name" value="SSF52738"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50122">
        <property type="entry name" value="CHEB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50123">
        <property type="entry name" value="CHER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0145">Chemotaxis</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CheB-type methylesterase" evidence="3">
        <location>
            <begin position="109"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="domain" description="CheR-type methyltransferase" evidence="4">
        <location>
            <begin position="290"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="116"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="142"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC91100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="570" mass="64037" checksum="2B139A325BE5CD21" modified="2018-07-18" version="1">MEITLQSSENLCRIGVLGHLESAAERDQLQHILDSADQTVQHQIDFYDADTLPPEIIAAIARCLTRLVQIKIITYHYLLTHSLMRLDLPVHPIAVRINKAQAQTKLQIQALALAGSANSLDKILPIIEQLPLGKMAVFVVQHVLENQINLLDTLLRTRTEYKVVMPQNLMPIEPGTIYVAPPGHHMKVAHGLVYLTRDKAVQYARPSIDVLFESLASEYGSQLMAILLCGFGRDGVDGCAKLTNAGACVIIENGAECENARALPDAAIEAGKFNHVLKLPVICSLVAATVYTNDTAITEHQLELFIDALLSHYGYDFRGYQQASFKRRIMHIMMKFELPNLLDFERAIFSDSTLFNRMMAEISVGVSTFFRHPEQFLLLREKIFPYLESFPVIKLWSAGCATGEEPYSLAILLEELGLLKRSRLFATDFNAYLIDIAKAGLFPQKSLETSQQNYEKSGGKNNFFSFIEQGSHYLTVKDSIRSTTLFHRHSLVDEGIFNEFQFIICRNVMIYFKPELQSKILERFARSLHRDGFLVLGPQDGMHHLARSAGFVPYITGSHVYRLGNGGLHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTS7</accession>
    <name>A0A2S9GTS7_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Peptidoglycan-associated protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">pal</name>
        <name evidence="11" type="ORF">S2091_4199</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the Pal lipoprotein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000029">
        <property type="protein sequence ID" value="PRC91103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91103">
        <property type="protein sequence ID" value="PRC91103"/>
        <property type="gene ID" value="S2091_4199"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07185">
        <property type="entry name" value="OmpA_C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02204">
        <property type="entry name" value="Pal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006664">
        <property type="entry name" value="OMP_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006665">
        <property type="entry name" value="OmpA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036737">
        <property type="entry name" value="OmpA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039001">
        <property type="entry name" value="Pal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014169">
        <property type="entry name" value="Pal_lipo_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00691">
        <property type="entry name" value="OmpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01021">
        <property type="entry name" value="OMPADOMAIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103088">
        <property type="entry name" value="SSF103088"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02802">
        <property type="entry name" value="Pal_lipo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51123">
        <property type="entry name" value="OMPA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1 7" id="KW-0132">Cell division</keyword>
    <keyword evidence="5 11" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="3 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0564">Palmitate</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015746174" description="Peptidoglycan-associated protein" evidence="9">
        <location>
            <begin position="21"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="domain" description="OmpA-like" evidence="10">
        <location>
            <begin position="59"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC91103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="175" mass="18210" checksum="CD67A17776C2B340" modified="2018-07-18" version="1">MKQTLTTIALATTAALLVTACGTTPKVATSVPTPVAAAPAPAQVRTVAAVVAPVLDPLNDAHGMLAKRSIYFDFDQYSIKPEFAALNTAHANYLVSHTARSIVIQGNTDSRGGAEYNLALGEKRAEAELKALAASGVPSSRMEAVSFGKEKPKASGNDAAAWAENRRADLVYAGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTT2</accession>
    <name>A0A2S9GTT2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Dipeptidyl peptidase IV (DPP IV) N-terminal region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_4126</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000028">
        <property type="protein sequence ID" value="PRC91125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91125">
        <property type="protein sequence ID" value="PRC91125"/>
        <property type="gene ID" value="S2091_4126"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002469">
        <property type="entry name" value="Peptidase_S9B_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00930">
        <property type="entry name" value="DPPIV_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015561704" evidence="1">
        <location>
            <begin position="24"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="domain" description="DPPIV_N" evidence="3">
        <location>
            <begin position="150"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S9" evidence="2">
        <location>
            <begin position="544"/>
            <end position="739"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC91125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="746" mass="83521" checksum="F1A084A8BD14B63E" modified="2018-07-18" version="1">MMRLLRLTLFAMTLSLASIPSFADRLTLERIHADPSLSGPTVSALKMSPDGSRVTFLRGRSDDRFQLDLWEFNLKDNSTKLLVDSKILLPEEKLSDAEKARRERERTASFHGISDYSWSPDGKQLLVTLAGNLYLADVAHPDQARRIVSGDVIDPKISPKGHYVSFVRAQNLFTIDLATNKEQQLTTDGGGAIHNAEAEFVAQEEMSQTSGYWWAPDDSAIAFKHFDETPVPNARRFEIYADHTEIIEQRYPAAGDPNVLVSLALVAPTGGKIHTVDLGKETDIYLVRADWSSDAQHLVYQRETRDQKRLDLVAVDASTLAQHTLLSETSPSWVSVGVARPHFLEKTKQFIWASERSGRNHVYLYDMNGQMLHAISSGEWGIDDVLAVDEKAGRVYVAANRDAVIDKQVYALAIDGSMADHPARVTKADGWHEANFSKHGSAFIDTWSDNDTPPQVSVRHADGSLITWLEHNELNSTHPYAPYKPSHVPTEFGTLKSADGQVLHYSILKPPGFDPAKHYPVFLSVYGGPHAQTVQRRWGDLFGQVMAQQGYVVFKLDNRGSFRRERRFTDVIYKNLGKNEVADQLVGIDWLAQQPYVDAKRIGVFGWSYGGFMTLRLLEAASDRIALGVAVAPVTEWDLYDTHYTEQFLTRPKDNPEGYQQSGVIAHLDGLKSPLLLIHGMADDNVLFVNSTRLIDEMQNRGILFNMMTYPGGKHGISKKSSNLHVFKTINNFFNQHFGVSGIDQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GU11</accession>
    <name>A0A2S9GU11_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Oligopeptide transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_4089</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000027">
        <property type="protein sequence ID" value="PRC91194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91194">
        <property type="protein sequence ID" value="PRC91194"/>
        <property type="gene ID" value="S2091_4089"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035673">
        <property type="term" value="F:oligopeptide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004814">
        <property type="entry name" value="Oligopep_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004813">
        <property type="entry name" value="OPT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045035">
        <property type="entry name" value="YSL-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31645">
        <property type="entry name" value="PTHR31645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03169">
        <property type="entry name" value="OPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00728">
        <property type="entry name" value="OPT_sfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00733">
        <property type="entry name" value="TIGR00733"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="40"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="71"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="101"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="159"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="221"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="263"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="312"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="344"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="381"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="412"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="516"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="546"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="592"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="635"/>
            <end position="652"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC91194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="658" mass="67494" checksum="019FDBA2FE384D02" modified="2018-07-18" version="1">MNSVTASMPKEITLRGVILGILITLIFTAAQVYLGLKVGLTFATSIPAAVISMALLSAFKDASIQENNIVQTIASAAGTLASVIFVLPGLLMIGWWVHVPFWPTFGACAIGGVLGVMYTMPLRRALVSQSDLPYPEGVAAAEVLKVGMSSRAGAAEGQAGLWAVIWGSLASALYAAGSALKLMADEMSIYFRVGNGSTGIGASSSLALIGAGHLMGITVGVAMLAGQIIAWGILVPILTNMYPLPGLSLVDHALKIWSTNVRMIGAGAIGTAAIITLAGMAKPVIGGLKSALDTARRVKEGSTDIPRTEQDLPIFIVGLVTLFSMLPAGWLLTSFLQGGVLQSVSVPLVAVGIAYILIAGMFAAAVCGYMAGLIGSSNSPVSGIAILTILGAALSVGAVARHLIGPDVAQALVAYALFITTVVLAVAVIGNDNLQDLKTGQLVDATPWRQQVGLLIGVLAGSVVVPPVLELLNHANGFVGAPNLDAISNQPLSAPQATLITTLAKGVIGGDLRWDLILFGAVIGLGLVLINFILKKSSNDKYSLPPLGVGLAIYLPGAVTLPVIIGAFSGWFFERAVSKHSWGESAKRLGVLIMSGFIVGESLFNVALAGLIVLSGKGEPLAIANSLSGGQSMTIALVVGATVVTGLYRWAAKRGKLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUA8</accession>
    <name>A0A2S9GUA8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Gram-negative porin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_3988</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000025">
        <property type="protein sequence ID" value="PRC91317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91317">
        <property type="protein sequence ID" value="PRC91317"/>
        <property type="gene ID" value="S2091_3988"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046930">
        <property type="term" value="C:pore complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015288">
        <property type="term" value="F:porin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006811">
        <property type="term" value="P:ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00342">
        <property type="entry name" value="gram_neg_porins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033900">
        <property type="entry name" value="Gram_neg_porin_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023614">
        <property type="entry name" value="Porin_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13609">
        <property type="entry name" value="Porin_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0406">Ion transport</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0626">Porin</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1134">Transmembrane beta strand</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015516365" evidence="4">
        <location>
            <begin position="29"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="domain" description="Porin_4" evidence="5">
        <location>
            <begin position="25"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF13609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC91317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="356" mass="37618" checksum="BAA8E4066AA856B0" modified="2018-07-18" version="1">MNRCSSAFWRKPIFILINTVCFLIPAMAQTNVTVSGLVDAEVNSQTSASTGQHTTSINGLSPGPNGGMQSSYLQFAGNEDLGGGMKASFTLGTFFRPGMGSDGRFDGDPLFSRDANVSLSGDFGGVTLGRQISPLYLSTLLFNPFADSFSYSPIIQHTYYAFSAGNVISADSGYSNAISYSTPNFSGLSAKLLYSLSGESGVAGSFSGNLLYFNGPFAATVAYENSTVSGTSNNTYTLGGGYPAGTTQKIAQLGASYDFAPVKLFFQYQNTDTTQTGLASLTLDTFQLGTSIAMGQGNVLASYAKTGGAIDHKTFSVGYDYNLSKSTDIYMAYMNDQATAYAYTLSSVGIGIRKRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUC0</accession>
    <name>A0A2S9GUC0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4041</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000026">
        <property type="protein sequence ID" value="PRC91256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91256">
        <property type="protein sequence ID" value="PRC91256"/>
        <property type="gene ID" value="S2091_4041"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="133" mass="15104" checksum="EC4438D91A2AA53A" modified="2018-07-18" version="1">MSPIFSKLNLTNQKTICVLNPPESFQEELSQLSGIQIIDNLKSDSNLSFALIFVSQKNQIDQIVPILANKAQGDAIVWFAYPKGTSKKYQCDFNRDTGWDTLKELGFDTVRQVAIDADWSALRFRRVEFIGSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUK0</accession>
    <name>A0A2S9GUK0_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Signal recognition particle protein</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Fifty-four homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">ffh</name>
        <name evidence="12" type="ORF">S2091_3928</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="8">The SRP-RNC complex is targeted to the cytoplasmic membrane.</text>
    </comment>
    <comment type="domain">
        <text evidence="8">Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the GTP-binding SRP family. SRP54 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000024">
        <property type="protein sequence ID" value="PRC91383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91383">
        <property type="protein sequence ID" value="PRC91383"/>
        <property type="gene ID" value="S2091_3928"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048500">
        <property type="term" value="C:signal recognition particle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008312">
        <property type="term" value="F:7S RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006614">
        <property type="term" value="P:SRP-dependent cotranslational protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00306">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036891">
        <property type="entry name" value="Signal_recog_part_SRP54_M_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013822">
        <property type="entry name" value="Signal_recog_particl_SRP54_hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004125">
        <property type="entry name" value="Signal_recog_particle_SRP54_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004780">
        <property type="entry name" value="SRP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036225">
        <property type="entry name" value="SRP/SRP_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022941">
        <property type="entry name" value="SRP54"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000897">
        <property type="entry name" value="SRP54_GTPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042101">
        <property type="entry name" value="SRP54_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11564">
        <property type="entry name" value="PTHR11564"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11564:SF7">
        <property type="entry name" value="PTHR11564:SF7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00448">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02881">
        <property type="entry name" value="SRP54_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02978">
        <property type="entry name" value="SRP_SPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00962">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00963">
        <property type="entry name" value="SRP54_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47364">
        <property type="entry name" value="SSF47364"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47446">
        <property type="entry name" value="SSF47446"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00959">
        <property type="entry name" value="ffh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 8" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6 8" id="KW-0733">Signal recognition particle</keyword>
    <feature type="domain" description="SRP54_N" evidence="11">
        <location>
            <begin position="1"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="domain" description="AAA" evidence="9">
        <location>
            <begin position="103"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="domain" description="SRP54" evidence="10">
        <location>
            <begin position="104"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="111"/>
            <end position="118"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="194"/>
            <end position="198"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="252"/>
            <end position="255"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PRC91383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="454" mass="48720" checksum="2B9A1796A334262E" modified="2018-07-18" version="1">MLDNLTQRLAKVVKTMRGEARLTETNTAEMLREVRLALLEADVALPAVREFIAKVKEKALGEDVISSLTPGQALVGVVQRELAALMGADLGAAASQLNFATQPPAIILMAGLQGVGKTTSVGKLAKFLRENHKKKVLTVSADVYRPAAIAQLQSVTEQVGADFFPSHSTDKPVDIALAALDFAKKHHHDVLIIDTAGRLGIDAAMMEEIAAVHTAVKPIETLFVVDAMVGQDAVNSARAFHDALPLTGIILTKLDGDSRGGAALSVRHITGVPIKFSGVSEKMDGLEAFDASRMANRILGMGDILALVAEAQKNMDVSAAQDLAQKMKSGGKFDLNDFKAQISQMKKMGGLSGLLDKLPAQMQQAAAGANMGMAEKQVRRMEGIINAMTPLERAKPDLIKASRKRRIATGAGVQIQEVNRMLAQFEQMQSMMKKLKGGGMMKMMRSMKGMMPNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUT8</accession>
    <name>A0A2S9GUT8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3773</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000022">
        <property type="protein sequence ID" value="PRC91495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91495">
        <property type="protein sequence ID" value="PRC91495"/>
        <property type="gene ID" value="S2091_3773"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="31" mass="3418" checksum="AF101FACBA80B1CF" modified="2018-07-18" version="1">MINFLLTLTTLGALLLTCLIYVIHLLGSDEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUW1</accession>
    <name>A0A2S9GUW1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ABC-type Fe3+-siderophore transport system permease component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_3800</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000022">
        <property type="protein sequence ID" value="PRC91522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91522">
        <property type="protein sequence ID" value="PRC91522"/>
        <property type="gene ID" value="S2091_3800"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037294">
        <property type="entry name" value="ABC_BtuC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000522">
        <property type="entry name" value="ABC_transptr_permease_BtuC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30472">
        <property type="entry name" value="PTHR30472"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01032">
        <property type="entry name" value="FecCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81345">
        <property type="entry name" value="SSF81345"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="67"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="99"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="128"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="159"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="208"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="248"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="286"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="316"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC91522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="344" mass="35837" checksum="ACA9773E0704B472" modified="2018-07-18" version="1">MSIPFNQSSRRAQLILASLLLASLFSLALACCVGSVSLSFSELLHAVVELLQGAPSSLSATLFELRLHRALSAFVTGGSLALAGVLMQALLRNPLADPYVLGISGGAAVGALTAILLCGAAWMVDLAAFGGAVAVSGLLFLLAYKDFKGSGSSEGSTPTLLLTGVIVSSGCLALITLFLSISPDSRLRSMVFWVIGDLSGAEVRYTPWIVMLGILAYVCNMARVINVAALYADSASTLGISVGRLRKILFFCAALLTASAVSSAGSIGFVGLIMPHACRFAWGPDHRLLLPASCIAGGCFLVLADTIARSLIAPMQLPVGVITSLIGVPLFLVQLHQHRRHQVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GV10</accession>
    <name>A0A2S9GV10_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Anhydro-N-acetylmuramic acid kinase</fullName>
            <ecNumber evidence="1">2.7.1.170</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">AnhMurNAc kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">anmK</name>
        <name evidence="2" type="ORF">S2091_3681</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>1,6-anhydro-N-acetyl-beta-muramate + ATP + H2O = ADP + H(+) + N-acetyl-D-muramate 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:24952"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58690"/>
            <dbReference type="ChEBI" id="CHEBI:58722"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.170"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-sugar metabolism; 1,6-anhydro-N-acetylmuramate degradation.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cell wall biogenesis; peptidoglycan recycling.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the anhydro-N-acetylmuramic acid kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.170" evidence="1"/>
    <dbReference type="EMBL" id="PUGF01000021">
        <property type="protein sequence ID" value="PRC91565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91565">
        <property type="protein sequence ID" value="PRC91565"/>
        <property type="gene ID" value="S2091_3681"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00343"/>
    <dbReference type="UniPathway" id="UPA00544"/>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016773">
        <property type="term" value="F:phosphotransferase activity, alcohol group as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097175">
        <property type="term" value="P:1,6-anhydro-N-acetyl-beta-muramic acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006040">
        <property type="term" value="P:amino sugar metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009254">
        <property type="term" value="P:peptidoglycan turnover"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01270">
        <property type="entry name" value="AnhMurNAc_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005338">
        <property type="entry name" value="Anhydro_N_Ac-Mur_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30605">
        <property type="entry name" value="PTHR30605"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03702">
        <property type="entry name" value="AnmK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="10"/>
            <end position="17"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="370" mass="39456" checksum="ADD967AF852E4382" modified="2018-07-18" version="1">MRYYIGLMSGTSLDGVDGVLVEMGETDAQLKQLAASYVPFTTELRASLLSLQISGFDEIHRASQAANQLVLVYAECVLHLLKNTGLAPAQITAIGVHGQTVRHRPEYGYTLQINNPALLVELTGIDVIADFRSRDIAAGGQGAPLVPAFHRSIFGKQGETRVVANIGGISNISILRADGSTHGFDTGPGNVLMDAWIMQHKSQAYDANGDWARLGQVNSALLAQLLDEPFLRLAPPKSTGRDLFHLDWLNQKLSLFSEVSAVDVQATLCAFTAHSLADAITTYAPDVQSAYICGGGAYNATLMAVIESALNSHSTSVNVQSTEVLGVSPNHVEALAFAWLAYRHTEGLAGNLAEVTGAAGERILGALYPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GV15</accession>
    <name>A0A2S9GV15_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Tyrosine--tRNA ligase</fullName>
            <ecNumber evidence="8">6.1.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Tyrosyl-tRNA synthetase</fullName>
            <shortName evidence="8">TyrRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">tyrS</name>
        <name evidence="11" type="ORF">S2091_3683</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>ATP + L-tyrosine + tRNA(Tyr) = AMP + diphosphate + H(+) + L-tyrosyl-tRNA(Tyr)</text>
            <dbReference type="Rhea" id="RHEA:10220"/>
            <dbReference type="Rhea" id="RHEA-COMP:9706"/>
            <dbReference type="Rhea" id="RHEA-COMP:9707"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58315"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78536"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.1" evidence="8"/>
    <dbReference type="EMBL" id="PUGF01000021">
        <property type="protein sequence ID" value="PRC91567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91567">
        <property type="protein sequence ID" value="PRC91567"/>
        <property type="gene ID" value="S2091_3683"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004831">
        <property type="term" value="F:tyrosine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006437">
        <property type="term" value="P:tyrosyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00805">
        <property type="entry name" value="TyrRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02007">
        <property type="entry name" value="Tyr_tRNA_synth_type2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002305">
        <property type="entry name" value="aa-tRNA-synth_Ic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002307">
        <property type="entry name" value="Tyr-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024088">
        <property type="entry name" value="Tyr-tRNA-ligase_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024108">
        <property type="entry name" value="Tyr-tRNA-ligase_bac_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11766">
        <property type="entry name" value="PTHR11766"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11766:SF1">
        <property type="entry name" value="PTHR11766:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01479">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00579">
        <property type="entry name" value="tRNA-synt_1b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01040">
        <property type="entry name" value="TRNASYNTHTYR"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00234">
        <property type="entry name" value="tyrS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 8 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 8 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 8 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 8 9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S4" evidence="10">
        <location>
            <begin position="357"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'HIGH' region" evidence="8">
        <location>
            <begin position="60"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'KMSKS' region" evidence="8">
        <location>
            <begin position="244"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="247"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC91567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="413" mass="45462" checksum="E22411029CB65EE3" modified="2018-07-18" version="1">MNPTSLLASKDLPLSDAVQNALAITKRGVDELLIESEFAQKLARSEKTGIPLRVKLGLDPTAPDLHLGHTVVLNKMRQLQNLGHTVIFLIGDFTSMIGDPSGRNITRPALTREQIEENAKSYFAQASLVLDAEKTEIRYNSEWSDPLGARGMIELSSKYTVARMMERDDFTKRFKAGTPISVHEFLYPLMQGYDSVALKADLELGGTDQKFNLLVGRELQKDYGQEPQCILTMPLLEGLDGVEKMSKSKGNYIGITEPGNTMFGKVMSISDHMMWRYYELLSSCSLADLAAHKKAVQEGKNPRDLKVALAQELVARFHNQQAADDALTDFMNRSKGGIPDDIPECTLSGAPLGIGQLLKQSNLCATSSEGLRMVEQGGVRINGEVISDKNLQVAKGEFVLQVGKRKFAKVTLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GV23</accession>
    <name>A0A2S9GV23_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Fumarylacetoacetate (FAA) hydrolase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3698</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000021">
        <property type="protein sequence ID" value="PRC91582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91582">
        <property type="protein sequence ID" value="PRC91582"/>
        <property type="gene ID" value="S2091_3698"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.850.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036663">
        <property type="entry name" value="Fumarylacetoacetase_C_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56529">
        <property type="entry name" value="SSF56529"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="276" mass="29890" checksum="7901D961D76B493A" modified="2018-07-18" version="1">MLSPAQADQYATQFLEAREQAKQMRPFPANAKISVEDAYFIARQIQAQRLAAGEVQIGRKIAFANQTLLKKYGRNAPIQGLVWTPLFSSTVRYLEETHVVQSLTGAVQPRLAPEIIFKLGTTPAPDASLTELADCLEWMAHGMEIVVCPFPRWEFNTADAIAAFGFHGSLLIGEPHQLASTTRHNLGGILGNTAVSLSCDSTLLSAGFGSNLLESPLHALWHLQQLLKNQPESTTLQAGEIVCTGTWTDLPQIKAGQTWSSAFSGASLAGLSISFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GV39</accession>
    <name>A0A2S9GV39_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">tRNA-dihydrouridine synthase B</fullName>
            <ecNumber evidence="10">1.3.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">dusB</name>
        <name evidence="14" type="ORF">S2091_3687</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4 10 11">Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 10">
            <text>a 5,6-dihydrouridine in tRNA + NAD(+) = a uridine in tRNA + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:54452"/>
            <dbReference type="Rhea" id="RHEA-COMP:13339"/>
            <dbReference type="Rhea" id="RHEA-COMP:13887"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>a 5,6-dihydrouridine in tRNA + NADP(+) = a uridine in tRNA + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:23624"/>
            <dbReference type="Rhea" id="RHEA-COMP:13339"/>
            <dbReference type="Rhea" id="RHEA-COMP:13887"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3 10 11">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the Dus family. DusB subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the dus family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.-" evidence="10"/>
    <dbReference type="EMBL" id="PUGF01000021">
        <property type="protein sequence ID" value="PRC91571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91571">
        <property type="protein sequence ID" value="PRC91571"/>
        <property type="gene ID" value="S2091_3687"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017150">
        <property type="term" value="F:tRNA dihydrouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02801">
        <property type="entry name" value="DUS_like_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02042">
        <property type="entry name" value="DusB_subfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035587">
        <property type="entry name" value="DUS-like_FMN-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001269">
        <property type="entry name" value="DUS_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032887">
        <property type="entry name" value="DusB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024036">
        <property type="entry name" value="tRNA-dHydroUridine_Synthase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004652">
        <property type="entry name" value="tRNA_dU_NifR3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018517">
        <property type="entry name" value="tRNA_hU_synthase_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01207">
        <property type="entry name" value="Dus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006621">
        <property type="entry name" value="Dus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00737">
        <property type="entry name" value="nifR3_yhdG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01136">
        <property type="entry name" value="UPF0034"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10 11" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6 10 11" id="KW-0288">FMN</keyword>
    <keyword evidence="10" id="KW-0521">NADP</keyword>
    <keyword evidence="9 10 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 10" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="7 10 11" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="10" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="Dus" evidence="13">
        <location>
            <begin position="1"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="10 12">
        <location>
            <position position="84"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="54"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="123"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="184"/>
            <end position="186"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="208"/>
            <end position="209"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00002790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR006621"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR006621-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="PRC91571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="335" mass="36636" checksum="0EE40224A7F01474" modified="2018-07-18" version="1">MAGVTDRPFRQLCKQLGAGYAVSEMSASNPRLWNTEKSSRRTNHEGEMEPKAVQIAGADPVMLAECAKHNVANGAQIIDINMGCPVKKVCDSWCGSALLQNEKLVGRILDAVVAAVDVPVTLKFRTGWNSENKNALNIAKMAESAGIAMLTLHGRTRADGYKGAAEYETIAAVKAAVNLPVVANGDITSPKKAAYVLKVTGADAVMIGRAAQGRPWIFREIAHYLATGEYLPAPLVSEVRGLMAEHLLAHYAFYGEFMGVRTARKHIGWYVHDLVGGEAFRQQMNKLESCELQLRAVQDFFDSQSNERLQYCPVVQFDDDWGGQFTQDSTEKQAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVB9</accession>
    <name>A0A2S9GVB9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putative threonine efflux protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_3605</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000020">
        <property type="protein sequence ID" value="PRC91667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91667">
        <property type="protein sequence ID" value="PRC91667"/>
        <property type="gene ID" value="S2091_3605"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001123">
        <property type="entry name" value="LeuE-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30086">
        <property type="entry name" value="PTHR30086"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01810">
        <property type="entry name" value="LysE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006324">
        <property type="entry name" value="LeuE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="39"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="71"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="113"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="151"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="183"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC91667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="205" mass="21618" checksum="69EE7924B3547E27" modified="2018-07-18" version="1">MSITNLWLFTATEAALSLSPGPAVIMVVAYGIARGQRGALFVTLGILAANALYFALSATGIGGLIAASPQLFHYIKWCGAAYLIYLGLSAIFGKASPITLSKMNANAQSGWRIFRGAALLQLSNPKSLLMFVSILPQFIDPGAPVGRQMLILAACSIIPEFFILLGYGMLASKASRTLTQQKYAVITERVAGCLVLMAGVMVAAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVJ7</accession>
    <name>A0A2S9GVJ7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3498</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000019">
        <property type="protein sequence ID" value="PRC91743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91743">
        <property type="protein sequence ID" value="PRC91743"/>
        <property type="gene ID" value="S2091_3498"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="60" mass="6577" checksum="FF59CB9D29CC8343" modified="2018-07-18" version="1">MKWVGMYVIGFFILICGLLVALWKLDILASIGTTWIVIAVVIAVGIDIIVSVSQSDINRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVR1</accession>
    <name>A0A2S9GVR1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Helix-turn-helix domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3559</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000019">
        <property type="protein sequence ID" value="PRC91804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91804">
        <property type="protein sequence ID" value="PRC91804"/>
        <property type="gene ID" value="S2091_3559"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041657">
        <property type="entry name" value="HTH_17"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12728">
        <property type="entry name" value="HTH_17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH_17" evidence="1">
        <location>
            <begin position="55"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="108" mass="12311" checksum="23B36EFE789D6D98" modified="2018-07-18" version="1">MVQMTLTAETLFTSLQHMPSSERERFFALISRKAFAENDNLSHEELFGHLQETEFTATEAAAYLDMSIATFRRYCKQEKITASSVVGTSHLYSLAALREFKNALKIIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GW15</accession>
    <name>A0A2S9GW15_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">TPR_21 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_3469</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000018">
        <property type="protein sequence ID" value="PRC91913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91913">
        <property type="protein sequence ID" value="PRC91913"/>
        <property type="gene ID" value="S2091_3469"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044877">
        <property type="term" value="F:protein-containing complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018704">
        <property type="entry name" value="TPR_21"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026039">
        <property type="entry name" value="YfgM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38035">
        <property type="entry name" value="PTHR38035"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09976">
        <property type="entry name" value="TPR_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006170">
        <property type="entry name" value="YfgM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0143">Chaperone</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="domain" description="TPR_21" evidence="3">
        <location>
            <begin position="15"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF09976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC91913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="220" mass="24499" checksum="349F943F3F2FE35F" modified="2018-07-18" version="1">MAYDHEEQEQLESLKAWWKQYGNLITWTLIIVLSIFSAWKAWGIYQVKQAGQASLLYEEMQKAIHDKDQVKVLRAVTDVQDKFAGTDYAQMASMLAAKNAFEANDLKTAKTQLMWVQEHGKTAEFKSLAKIRLAGILLDEKSYDDALKVLSGDFPAELASAVADRKGDIFVAQNKTDEARTAYQLAIDKSTDKNPGRQLIQLKLDAIGGSPAKVAIESGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GW49</accession>
    <name>A0A2S9GW49_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Helix-turn-helix domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3291</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000017">
        <property type="protein sequence ID" value="PRC91949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91949">
        <property type="protein sequence ID" value="PRC91949"/>
        <property type="gene ID" value="S2091_3291"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="11"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="146" mass="15804" checksum="D8F9814FAE863E7D" modified="2018-07-18" version="1">MTNLLDIGVRLKEERKRLGMSQTAFAAIGGTKRASQFNYESGGRAPDAAYLAAISETGVDVLYVLTGQRVSMPRHVLGVAQTQQTYQNSSNVPSQVTAEPHETEVFGVARNRREAALLDNFRHSNDEGRDVISAAGNALAKLGKKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWE0</accession>
    <name>A0A2S9GWE0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Peptidase family M50</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_3180</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the peptidase M50B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000016">
        <property type="protein sequence ID" value="PRC92045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92045">
        <property type="protein sequence ID" value="PRC92045"/>
        <property type="gene ID" value="S2091_3180"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008915">
        <property type="entry name" value="Peptidase_M50"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02163">
        <property type="entry name" value="Peptidase_M50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="185"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="255"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="284"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="317"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="343"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="381"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M50" evidence="8">
        <location>
            <begin position="203"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC92045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="415" mass="46422" checksum="D789EEA7860928EB" modified="2018-07-18" version="1">MGLIVRFRWLAAVTSVATYEDFDKPAPAEGYFGSCLDASQRKSNVELLKLDCLGQPLILTGSMAGWQQLFLGSTLVSQLAATADTENRRVHEFELQTELKLNTNPEQPDLSRLRCRLESSLIWQPFNLDYQFFINDELVAQGQRNTKDIEQQVPTQTAQASKPFSFIGLGALLMKLLKSAKVVKVILAGVSLAAYSWLFSFQFAVALITCLVFHEYGHIRAMRYFGMKTKGIYLIPFLGGAAVTEDKINTRWQNVAISMMGPCFGLLMSLACMVAFWFSDNMFFAGLAVFNAMFNLFNLLPVLPLDGGHILKSISFSMNNTFGIVLCILGALIGVVLCYTFHLTLLGFFLLIGCLDIFMEWRTRHNSHLLPLDRYGQIFSAVWYCALVASLIGIIVYFAGHGDEMLTMPMHILKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWG2</accession>
    <name>A0A2S9GWG2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Growth regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3338</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000017">
        <property type="protein sequence ID" value="PRC91996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91996">
        <property type="protein sequence ID" value="PRC91996"/>
        <property type="gene ID" value="S2091_3338"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007159">
        <property type="entry name" value="SpoVT-AbrB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037914">
        <property type="entry name" value="SpoVT-AbrB_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04014">
        <property type="entry name" value="MazE_antitoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00966">
        <property type="entry name" value="SpoVT_AbrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89447">
        <property type="entry name" value="SSF89447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SpoVT-AbrB" evidence="1">
        <location>
            <begin position="6"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="83" mass="9080" checksum="CDD353EFCC1F7222" modified="2018-07-18" version="1">MELSIQKWGNSAAVRLPTELLGMLKVTLGDKLSVDVRPDGIMLKAKRPAYALTDLVAQCDMTASEPADLAAWNNIKPVGREVW</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWM0</accession>
    <name>A0A2S9GWM0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Threonine dehydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_3191</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000016">
        <property type="protein sequence ID" value="PRC92056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92056">
        <property type="protein sequence ID" value="PRC92056"/>
        <property type="gene ID" value="S2091_3191"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="PLP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="Trypto_synt_PLP_dependent"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="SSF53686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PALP" evidence="3">
        <location>
            <begin position="24"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC92056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="332" mass="35150" checksum="D02BC4193B4D820A" modified="2018-07-18" version="1">MSLLPSKQQLDAAAQIVYAAMPATPQYSWPLINEALGCEVWIKHENHTPTGAFKMRGGLVYVHELAQRAPTVKHLVSATRGNHGLSVGFAAQRHGMTAHIVVPRGNSTEKNAAMRALGVDLIEFGDDFQDCREHAAQLAKKNDWHMIPSMHPDLLSGVASYWMELFTAQPDLDIIFVPIGQGSGICAAAAAKQALGLKTKIVGVVSAHALAYKSSFEAGCKIEAPVSTKLADGLACRIPDDVSLEIIMNTVDRIVAVTDTEVAAAMKLLFVATHNVAEGAGAAALAAALQFKAGLAGLKVGVPLCGGNVDAKQFSIIIGAWNYAEKDTEVCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWV8</accession>
    <name>A0A2S9GWV8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Response regulator receiver domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3123</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92207">
        <property type="protein sequence ID" value="PRC92207"/>
        <property type="gene ID" value="S2091_3123"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="3"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="138" mass="14774" checksum="2DE6464732E2FC90" modified="2018-07-18" version="1">MLKVVVIDGNAISRGLLNTMLTNGGHEVIGGGNVSSSSIARMVKLKPQLICMDLGQVEDDKMAVLDNIRKELPKTIVFLVSNSFDAETIKQGQEHGVRGFIVKPFNSATVLTSIRTAVLTFVREIKQAKAQGEPPAGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWX4</accession>
    <name>A0A2S9GWX4_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Ribonuclease HII</fullName>
            <shortName evidence="11">RNase HII</shortName>
            <ecNumber evidence="11">3.1.26.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">rnhB</name>
        <name evidence="14" type="ORF">S2091_3139</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 11 12">Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11 12">
            <text>Endonucleolytic cleavage to 5'-phosphomonoester.</text>
            <dbReference type="EC" id="3.1.26.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <cofactor evidence="11">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="11">Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 11 12">Belongs to the RNase HII family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.26.4" evidence="11"/>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92223">
        <property type="protein sequence ID" value="PRC92223"/>
        <property type="gene ID" value="S2091_3139"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004523">
        <property type="term" value="F:RNA-DNA hybrid ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006401">
        <property type="term" value="P:RNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07182">
        <property type="entry name" value="RNase_HII_bacteria_HII_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00052_B">
        <property type="entry name" value="RNase_HII_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022898">
        <property type="entry name" value="RNase_HII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001352">
        <property type="entry name" value="RNase_HII/HIII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024567">
        <property type="entry name" value="RNase_HII/HIII_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10954">
        <property type="entry name" value="PTHR10954"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10954:SF18">
        <property type="entry name" value="PTHR10954:SF18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01351">
        <property type="entry name" value="RNase_HII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 11 12" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="9 11 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10 11" id="KW-0464">Manganese</keyword>
    <keyword evidence="7 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 11 12" id="KW-0540">Nuclease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNase_HII" evidence="13">
        <location>
            <begin position="21"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="24"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="25"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="116"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="PRC92223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="205" mass="22130" checksum="45E5972FE5F5E84A" modified="2018-07-18" version="1">MSNYELPLSEVEFDFENQLICGVDEAGRGPLAGAVFAAAVILDPAHPIAGLRDSKKLSEAKRDQLAIEIKKHALSWCIAQASEQEIDQINILQATMLAMQRAVQGLSITPSLALIDGNRSPILSMASQAIIKGDDKVEAISAASILAKTARDASLMELHATYPQYAFDKHKGYPTALHLALLKEHGVSPVHRVSYAPVRALLPKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GX02</accession>
    <name>A0A2S9GX02_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Molybdenum cofactor guanylyltransferase</fullName>
            <shortName evidence="5">MoCo guanylyltransferase</shortName>
            <ecNumber evidence="5">2.7.7.77</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">GTP:molybdopterin guanylyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Mo-MPT guanylyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Molybdopterin guanylyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Molybdopterin-guanine dinucleotide synthase</fullName>
            <shortName evidence="5">MGD synthase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">mobA</name>
        <name evidence="7" type="ORF">S2091_3144</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>GTP + H(+) + Mo-molybdopterin = diphosphate + Mo-molybdopterin guanine dinucleotide</text>
            <dbReference type="Rhea" id="RHEA:34243"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
            <dbReference type="ChEBI" id="CHEBI:71310"/>
            <dbReference type="EC" id="2.7.7.77"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="5">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="5">The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the MobA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.77" evidence="5"/>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92228">
        <property type="protein sequence ID" value="PRC92228"/>
        <property type="gene ID" value="S2091_3144"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061603">
        <property type="term" value="F:molybdenum cofactor guanylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006777">
        <property type="term" value="P:Mo-molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02503">
        <property type="entry name" value="MobA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00316">
        <property type="entry name" value="MobA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025877">
        <property type="entry name" value="MobA-like_NTP_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013482">
        <property type="entry name" value="Molybde_CF_guanTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12804">
        <property type="entry name" value="NTP_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02665">
        <property type="entry name" value="molyb_mobA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 5" id="KW-0501">Molybdenum cofactor biosynthesis</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NTP_transf_3" evidence="6">
        <location>
            <begin position="14"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="17"/>
            <end position="19"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="30"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="76"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF12804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC92228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="206" mass="22696" checksum="F20C04BD40367018" modified="2018-07-18" version="1">MNSTIDSILSATTGLILAGGRATRMQNCDKGLQELDGERLIAHVITRLAPQVTSIAISANRNLDEYAKFGYPVWPDISPDFAGPLAGLESGLTYCQTPYLLTVPCDSPFLPTNLAQRLMNKLQHQQADIAIACTGELAHLQAQPVFCLLKASCLEQLQHYLAGGGRKMDGWYTELTVARVYFEDEAEFRNINTREELLACSNFKKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GX97</accession>
    <name>A0A2S9GX97_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein putative amidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_3004</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the creatininase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92345">
        <property type="protein sequence ID" value="PRC92345"/>
        <property type="gene ID" value="S2091_3004"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10310">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024087">
        <property type="entry name" value="Creatininase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003785">
        <property type="entry name" value="Creatininase/forma_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35005">
        <property type="entry name" value="PTHR35005"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02633">
        <property type="entry name" value="Creatininase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102215">
        <property type="entry name" value="SSF102215"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015473153" evidence="5">
        <location>
            <begin position="26"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00024029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC92345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="281" mass="30212" checksum="4CFB25DD5EEC8D58" modified="2018-07-18" version="1">MRILLKHHLSSVLICWFALALPAAAEPKIASSAVQLEELTSSEVRDRLAAGSVNNPINTILIPIGATEQTGPYVALGKHNFRAKSLADQIAQKLGNALVAPVIAYVPEGSINPPVAHMRFAGTISIPDAAFDAVLEGTARSFKQHGFRYIVFLGDHGGYKKNLERVAQKLNQEWAKDPSSRVIFLSEYYRLSSAGFDAILKKRGFTDVEIGTHAGLADTALTMAIDKNLVRSDAMIHNPKPTEHDGVYGDPRRATAELGQLGVQLIVDGSVAAIRAATSGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXB6</accession>
    <name>A0A2S9GXB6_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Enolase</fullName>
            <ecNumber evidence="8">4.2.1.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">2-phospho-D-glycerate hydro-lyase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">2-phosphoglycerate dehydratase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">eno</name>
        <name evidence="13" type="ORF">S2091_3009</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>(2R)-2-phosphoglycerate = H2O + phosphoenolpyruvate</text>
            <dbReference type="Rhea" id="RHEA:10164"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:58289"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="EC" id="4.2.1.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="activity regulation">
        <text evidence="8">The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 4/5.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="8">Secreted</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="8">Cell surface</location>
        </subcellularLocation>
        <text evidence="8">Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the enolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.11" evidence="8"/>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92350">
        <property type="protein sequence ID" value="PRC92350"/>
        <property type="gene ID" value="S2091_3009"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00187"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009986">
        <property type="term" value="C:cell surface"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000015">
        <property type="term" value="C:phosphopyruvate hydratase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004634">
        <property type="term" value="F:phosphopyruvate hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03313">
        <property type="entry name" value="enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00318">
        <property type="entry name" value="Enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000941">
        <property type="entry name" value="Enolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036849">
        <property type="entry name" value="Enolase-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029017">
        <property type="entry name" value="Enolase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020810">
        <property type="entry name" value="Enolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020809">
        <property type="entry name" value="Enolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020811">
        <property type="entry name" value="Enolase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11902">
        <property type="entry name" value="PTHR11902"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00113">
        <property type="entry name" value="Enolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03952">
        <property type="entry name" value="Enolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001400">
        <property type="entry name" value="Enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00148">
        <property type="entry name" value="ENOLASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00002">
        <property type="entry name" value="enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01192">
        <property type="entry name" value="Enolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01193">
        <property type="entry name" value="Enolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51604">
        <property type="entry name" value="SSF51604"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54826">
        <property type="entry name" value="SSF54826"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01060">
        <property type="entry name" value="eno"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00164">
        <property type="entry name" value="ENOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="7 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="5 8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0964">Secreted</keyword>
    <feature type="domain" description="Enolase_N" evidence="12">
        <location>
            <begin position="4"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="Enolase_C" evidence="11">
        <location>
            <begin position="139"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="8 10">
        <location>
            <begin position="364"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="8 9">
        <location>
            <position position="205"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8 9">
        <location>
            <position position="337"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8 10">
        <location>
            <position position="155"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 10">
        <location>
            <position position="164"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="242"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 10">
        <location>
            <position position="285"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8 10">
        <location>
            <position position="312"/>
        </location>
    </feature>
    <feature type="binding site" description="covalent; in inhibited form" evidence="8">
        <location>
            <position position="337"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 10">
        <location>
            <position position="388"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00318"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR001400-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR001400-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM01192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM01193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PRC92350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="427" mass="45788" checksum="46B217CC941CDB36" modified="2018-07-18" version="1">MSAIVDIIGREIMDSRGNPTVECDVLLESGVMGRAAVPSGASTGSREAVELRDGDKSRFMGKGVLRACENINTEIAEAIMGLDANEQAFLDRTLIDLDGTENKSRLGANAILAVSMAVAKAAAEEAGLPLYRYFGGSGAMQLPVPMMNVINGGAHADNNLDIQEFMIIPIGAPSFKEAIRYGAEVFHHLKKILQDKGLTTAVGDEGGFAPSVANHEEAIKLIIQAIESAGYTPGTQIALGLDCAASEFFKDGKYHLEGEGLVLSATDFTNLLATWCDKYPIISIEDAMAEGDWEGWATLTKVLGKKVQLVGDDLFVTNTKILKEGIQKNIANSILIKINQIGTLTETFAAIEMAKRAGYTAVISHRSGETEDSTIADIAVGTNALQIKTGSMSRSDRMAKYNQLLRIEEDLGDIASYPGRDAFYNLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXC2</accession>
    <name>A0A2S9GXC2_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNA polymerase sigma factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_3022</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92363">
        <property type="protein sequence ID" value="PRC92363"/>
        <property type="gene ID" value="S2091_3022"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006950">
        <property type="term" value="P:response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000838">
        <property type="entry name" value="RNA_pol_sigma70_ECF_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01063">
        <property type="entry name" value="SIGMA70_ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="3">
        <location>
            <begin position="35"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="4">
        <location>
            <begin position="130"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC92363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="199" mass="22287" checksum="260587D0019A3892" modified="2018-07-18" version="1">MNTPVTTASEPGTNDLALVTRVLLNDDRHAFTELTRRHQSTVRLLLRRLTKNDHALADDLAQETFILVYKNLRQYRGDAKFSTWIFRIAYNSFLAHQRSAQAKELHVEDSVQLEESSQDISSGSSDMKLDLQRAMACLSDSERAAIVQCYYQDLSHEEAAYVLDCPLGTVKTNVARAKEKLKTTLSAWAPAATLTAGNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXD2</accession>
    <name>A0A2S9GXD2_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Molybdopterin molybdenumtransferase</fullName>
            <ecNumber evidence="7">2.10.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_3032</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 7">Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>adenylyl-molybdopterin + H(+) + molybdate = AMP + H2O + Mo-molybdopterin</text>
            <dbReference type="Rhea" id="RHEA:35047"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:36264"/>
            <dbReference type="ChEBI" id="CHEBI:62727"/>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.10.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 7">Cofactor biosynthesis; molybdopterin biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 7">Belongs to the MoeA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.10.1.1" evidence="7"/>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92373">
        <property type="protein sequence ID" value="PRC92373"/>
        <property type="gene ID" value="S2091_3032"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00344"/>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061599">
        <property type="term" value="F:molybdopterin molybdotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006777">
        <property type="term" value="P:Mo-molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032324">
        <property type="term" value="P:molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00887">
        <property type="entry name" value="MoeA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.340.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.980.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036425">
        <property type="entry name" value="MoaB/Mog-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001453">
        <property type="entry name" value="MoaB/Mog_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008284">
        <property type="entry name" value="MoCF_biosynth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038987">
        <property type="entry name" value="MoeA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005111">
        <property type="entry name" value="MoeA_C_domain_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036688">
        <property type="entry name" value="MoeA_C_domain_IV_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005110">
        <property type="entry name" value="MoeA_linker/N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036135">
        <property type="entry name" value="MoeA_linker/N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10192">
        <property type="entry name" value="PTHR10192"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00994">
        <property type="entry name" value="MoCF_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03454">
        <property type="entry name" value="MoeA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03453">
        <property type="entry name" value="MoeA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00852">
        <property type="entry name" value="MoCF_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53218">
        <property type="entry name" value="SSF53218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63867">
        <property type="entry name" value="SSF63867"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63882">
        <property type="entry name" value="SSF63882"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00177">
        <property type="entry name" value="molyb_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01079">
        <property type="entry name" value="MOCF_BIOSYNTHESIS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 7" id="KW-0500">Molybdenum</keyword>
    <keyword evidence="6 7" id="KW-0501">Molybdenum cofactor biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="MoCF_biosynth" evidence="8">
        <location>
            <begin position="186"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC92373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="407" mass="43125" checksum="3C8F49A93CC117B8" modified="2018-07-18" version="1">MKNSAPLLSVNEALSTLLAAATQAAISDPIHLPTLSSNGRILAADICATMDVPSAENSQMDGYALNSADAHSKTPLLISQRIAAGHIGTALQPGTVARIFTGAIMPDGADTVVMQEQCEVIETPQGAAVRLLHTPQAGEWVRHIGEDIRRGSVILSAGTRLRAQELGLAASVGFATLPVQRPLRVAVFFTGDELVMPGEPLPVGAIYNSNRFLITALLENLGCQIHDYGIVPDTLVATRATLKLAAQENDVVITSGGVSVGDEDHIKPAVQAEGRLNLWQIAVKPGKPLAFGEVGSAFFLGLPGNPVSSFVTFLLFVRPFLLRLQGVTDVAPKSYTMRADFTWAKADKRNEFLRAKLNANGGLDLYPSQGSAVLSSTVWGDGLVDNPAGQTIQTGDMVKFIPFSEIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXL7</accession>
    <name>A0A2S9GXL7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Outer membrane insertion C-terminal signal</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2826</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92451">
        <property type="protein sequence ID" value="PRC92451"/>
        <property type="gene ID" value="S2091_2826"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025737">
        <property type="entry name" value="Phenol_MetA_deg_put"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13557">
        <property type="entry name" value="Phenol_MetA_deg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5016395644" evidence="1">
        <location>
            <begin position="27"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="252" mass="28496" checksum="0C939B501B5D4A3B" modified="2018-07-18" version="1">MTHYPRVFIALFLFWISLFASLLANAGPPFLTDDPEPVEYQHSELYISTMQTQTSNGTTGTLPHIEYNYGAAPDLQLHIIIPYEFNSPNNGSRQLGLGDIELGAKYRFIQETDSMPMIGVFPLIETPSGDAEKGLGNGKTQVFLPIWLQKKWGSWQTYGGGGYWINHAPDAKNHWFYGWQLQKEISEQLTLGGEIFYNTEQVQGRGASSGFNVGANYNFDEHNHLLFSIGKGITNINQTNQRSLYLGYQWTW</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXM3</accession>
    <name>A0A2S9GXM3_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Pseudouridine synthase</fullName>
            <ecNumber evidence="3">5.4.99.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_2838</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the pseudouridine synthase RsuA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.-" evidence="3"/>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92463">
        <property type="protein sequence ID" value="PRC92463"/>
        <property type="gene ID" value="S2091_2838"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120159">
        <property type="term" value="F:rRNA pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000455">
        <property type="term" value="P:enzyme-directed rRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1560">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.580">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042092">
        <property type="entry name" value="PsdUridine_s_RsuA/RluB/E/F_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006145">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000748">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluB/E/F"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018496">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020094">
        <property type="entry name" value="TruA/RsuA/RluB/E/F_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00849">
        <property type="entry name" value="PseudoU_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00093">
        <property type="entry name" value="TIGR00093"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01149">
        <property type="entry name" value="PSI_RSU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PseudoU_synth_2" evidence="4">
        <location>
            <begin position="65"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC92463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="240" mass="27019" checksum="EA8E4667F05DADFD" modified="2018-07-18" version="1">MTKLTLDRILQSQGFGTRKWCRSLIADGEIRIGGQVITDYRTSFDPTGLEFELFDEVWRYREHVYIALNKPANFECSRKPSHHPGVLTLLSEQCSWRDVQPVGRLDHDTTGLLLMSDDGAFIHAQSSPKRHVPKVYLATTQEPVTDELVAQLLAGVQLHDEPEPLMALVCKKVAENQCEIVLEQGKYHQVKRMLAAAGNHCAALQRVAVGNLTLAELGLEEGEWCYLEEHHLALLVPRVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXQ4</accession>
    <name>A0A2S9GXQ4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Metal-dependent hydrolases of the beta-lactamase superfamily III</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2882</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92507">
        <property type="protein sequence ID" value="PRC92507"/>
        <property type="gene ID" value="S2091_2882"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07719">
        <property type="entry name" value="arylsulfatase_AtsA-like_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044094">
        <property type="entry name" value="AtsA-like_MBL-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12706">
        <property type="entry name" value="Lactamase_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015767691" evidence="1">
        <location>
            <begin position="27"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="domain" description="Lactamase_B" evidence="2">
        <location>
            <begin position="67"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="313" mass="34244" checksum="8585CA069FA62108" modified="2018-07-18" version="1">MHIDFNRRKLLAAFAALGLVNISSLAQTTAPGKKTRLILLGTGGGPTPKESRSAPAQVIVINDVAYVIDCGNGVARQFVSAGLKLSAIRNVFITHHHSDHNADYGNLLLLAWSADLAHRVDTYGPPPLVRMTRQFLELNDYDIQTRITDEGRPPLAPLIHAHEFSEPGLIMQDENVKVTATLVRHPPVVSAFAYRFDTADRSIVISGDTAPSDNLIRLAQGADVLVHEVMYMPALENLLTIETNAIRLKEHLLAAHSTAEQIGKVATAAKVKTLVLSHFVPGGYPYLDDHVWLDAVRPHFTGEIIVGRDLMEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXX7</accession>
    <name>A0A2S9GXX7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative amino acid aldolase or racemase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2615</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DSD1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92560">
        <property type="protein sequence ID" value="PRC92560"/>
        <property type="gene ID" value="S2091_2615"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.37.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001608">
        <property type="entry name" value="Ala_racemase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026956">
        <property type="entry name" value="D-ser_dehydrat-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042208">
        <property type="entry name" value="D-ser_dehydrat-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029066">
        <property type="entry name" value="PLP-binding_barrel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01168">
        <property type="entry name" value="Ala_racemase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14031">
        <property type="entry name" value="D-ser_dehydrat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01119">
        <property type="entry name" value="D-ser_dehydrat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51419">
        <property type="entry name" value="SSF51419"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="D-ser_dehydrat" evidence="2">
        <location>
            <begin position="317"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="434" mass="47726" checksum="28C8E1AEC24C851E" modified="2018-07-18" version="1">MLNLTSLSEQILLPGTKGLALSAPLKQADIAQQNWNVLDGDTSFPVAVLKRSALRFNLVWMKQFCASHNILLAPHGKTTMSPQIFDMQLANGAWGMTLATVNQLHIAYRYGVKRVLLANQLISASDIRSALSLLKNDPEFIFYALVDSLENVQALSNAVQQAGLDRPLPLLVELGFSGGRTGCRSNADALTLARAIHASPHLELAGIEGYEGLLVTKKREEDLVKVRQFVSDLIELTKSVDAENLFGGESILLSAGGSAYFDLVAHGFKQVQSWSRPLISILRSGCYITHDHGFYHGLIDEMQEREATSVGSKLVPALEVWSMVQSRPEPDLAILTMGKRDASYDIDLPFPLYTHKIGQAHSPQTLPTDCKIEKMNDQHAYLRLPKDSPLCTSLQVGDLVACGISHPCTTFDKWPLLLIVNDNYQVASAINTFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GY68</accession>
    <name>A0A2S9GY68_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Terminase-like family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2719</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92664">
        <property type="protein sequence ID" value="PRC92664"/>
        <property type="gene ID" value="S2091_2719"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035421">
        <property type="entry name" value="Terminase_6C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17289">
        <property type="entry name" value="Terminase_6C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Terminase_6C" evidence="1">
        <location>
            <begin position="216"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF17289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="385" mass="43799" checksum="8A2161AABAF4CE4F" modified="2018-07-18" version="1">MRRAAKLAVKWEVSTDDEIWYAAPTFKQAKRVFWRRLKKAIPPGWRAGKPNETECSITLTSGHVIRIVGLDSYDNLRGSGLFFVLVDEWADCPYEAWEEVLRPMLSTCRYCIDGVEYRGGHALRIGTPKGFNHCYDTYLAGQGRKPDHKSWLYTSLDGGNIPDEEIEAARSSMDPRTFRQEYEASFENYSGVIYYCFDRRKNHTDDTVQKGDELHIGMDFNVGQMAAVVFVIRNGFPRAVYEFMGVFDTPAMIEKIKARYVDHRIEVYPDASGNNRKTNNASESDISLLKKAGFIVRVNPANPAVKDRINSKNAMLCNTYSERRLLINTTTCPKYTQGLERQIWTEKGDPDKTSGFDHGNDAGGYFIVSKFPITKRTITITGLNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GY69</accession>
    <name>A0A2S9GY69_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2730</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92675">
        <property type="protein sequence ID" value="PRC92675"/>
        <property type="gene ID" value="S2091_2730"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044000">
        <property type="entry name" value="Phage_tube_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18906">
        <property type="entry name" value="Phage_tube_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="408" mass="43086" checksum="E28CCDC498F42A82" modified="2018-07-18" version="1">MIATGIAKLLRYKKETTWGVQASNVGGQALRRVTSNLDLKKATFGSKELRPDFQVADFRHGGRSVDGTISGELSVGTYGDFMGSICRQAWAAKATTGAITTVAAASTVGAQGTFTLSAGSFLAMGFDNGDVVTCTGWTTTGATNNNHNFYLTNVTALVMTGVFLDGVPMGTKIAGDSVTITQAGKKNYLATSGQVNDSYSIEHWFSDIQQSETFVGCRISSMDIKLPSNGFAMIDTAFMGKDMIPMITGGPYFTSPASISTGGNLAGVNGQLYVQGNQVGLITGMNIKINANMTSGEVIGSPTRPDVFMGAMDVSGQLTVYFIDNVMRDLFVNETEASVQVVFTSNNTATADFIAFTLPRIKLGGGSKDDGQKGLIMTMPYTALLNIYGGVNLATPYTTLAIQDSRVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYC0</accession>
    <name>A0A2S9GYC0_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Adenosylhomocysteine nucleosidase</fullName>
            <ecNumber evidence="2">3.2.2.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_2452</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-methionine biosynthesis via salvage pathway; S-methyl-5-thio-alpha-D-ribose 1-phosphate from S-methyl-5'-thioadenosine (hydrolase route): step 1/2.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.2.9" evidence="2"/>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92722">
        <property type="protein sequence ID" value="PRC92722"/>
        <property type="gene ID" value="S2091_2452"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00904">
        <property type="reaction ID" value="UER00871"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008782">
        <property type="term" value="F:adenosylhomocysteine nucleosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008930">
        <property type="term" value="F:methylthioadenosine nucleosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019509">
        <property type="term" value="P:L-methionine salvage from methylthioadenosine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009164">
        <property type="term" value="P:nucleoside catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1580">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010049">
        <property type="entry name" value="MTA_SAH_Nsdase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000845">
        <property type="entry name" value="Nucleoside_phosphorylase_d"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035994">
        <property type="entry name" value="Nucleoside_phosphorylase_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01048">
        <property type="entry name" value="PNP_UDP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53167">
        <property type="entry name" value="SSF53167"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01704">
        <property type="entry name" value="MTA/SAH-Nsdase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PNP_UDP_1" evidence="6">
        <location>
            <begin position="2"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC92722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="261" mass="28430" checksum="9F206BAFC68AAEA3" modified="2018-07-18" version="1">MTIGIMAAIHDEIAELIEAITQQDKSQTHHIGMRDYYVGELEGQACVLVLARMGKVAASATAVSLIREFGVSEILFSGLAGGLAEHVQVGDVVVADRLIQHDMDARPFFPQHEIPLLGVTEFVVSQSLREELQTATRGFFKHDLAKKISAEKLAQFGLTKPDLHVGMIASGDQFIGSETEVARLRKTLPTALAVEMEGAAVAQICHEHAVPCAILRTISDRADSEAHIDFNQFLVGVASHYSCGIMRRFLANRTRVNNSLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYG0</accession>
    <name>A0A2S9GYG0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2751</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92696">
        <property type="protein sequence ID" value="PRC92696"/>
        <property type="gene ID" value="S2091_2751"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015525454" evidence="2">
        <location>
            <begin position="20"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="99"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="189" mass="20272" checksum="0F1DDEFD248C7AF2" modified="2018-07-18" version="1">MKLRHIVMAVGFVAAAGLAIFGDKSPADHVVEPVARAATTMTPSHDQTLLAAINSDTRASKNTPSSDGAKPEPVILVLLTREEAMHKIVSTNNSTLFGNQNWLPPAPPPPKPVPPPPPTAPSMPFTYLGKKMEDGVWEVYLARGDTIAIVHTNSLIEATYRVDSITPPTLTMTYLPLKQTQTITVGDAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYG2</accession>
    <name>A0A2S9GYG2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2495</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92765">
        <property type="protein sequence ID" value="PRC92765"/>
        <property type="gene ID" value="S2091_2495"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016884">
        <property type="term" value="F:carbon-nitrogen ligase activity, with glutamine as amido-N-donor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1510.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003789">
        <property type="entry name" value="Asn/Gln_tRNA_amidoTrase-B-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023168">
        <property type="entry name" value="GatB_Yqey_C_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019004">
        <property type="entry name" value="YqeY/Aim41"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042184">
        <property type="entry name" value="YqeY/Aim41_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28055">
        <property type="entry name" value="PTHR28055"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09424">
        <property type="entry name" value="YqeY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89095">
        <property type="entry name" value="SSF89095"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="148" mass="16005" checksum="8E01859FA18D393D" modified="2018-07-18" version="1">MSLKEQITEDMKNAMRAKETAKLGTIRLITAAMKQKEVDERIELNDTMVLAIIEKMIKQRKDSISQFEAGARQDLADIEKAELVILSAYMPAAMSDAEIALEVAAAVAEVNPTGPQDMGKVMAIVKAKLAGRADMTVVSGLVKAALTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYG6</accession>
    <name>A0A2S9GYG6_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Ubiquinol oxidase subunit 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">S2091_2483</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cell membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the cytochrome c oxidase subunit 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92753">
        <property type="protein sequence ID" value="PRC92753"/>
        <property type="gene ID" value="S2091_2483"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070469">
        <property type="term" value="C:respirasome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009486">
        <property type="term" value="F:cytochrome bo3 ubiquinol oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004129">
        <property type="term" value="F:cytochrome-c oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016682">
        <property type="term" value="F:oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04212">
        <property type="entry name" value="CuRO_UO_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045187">
        <property type="entry name" value="CcO_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002429">
        <property type="entry name" value="CcO_II-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010514">
        <property type="entry name" value="COX_ARM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034227">
        <property type="entry name" value="CuRO_UO_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011759">
        <property type="entry name" value="Cyt_c_oxidase_su2_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036257">
        <property type="entry name" value="Cyt_c_oxidase_su2_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006333">
        <property type="entry name" value="Cyt_o_ubiquinol_oxidase_su2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22888">
        <property type="entry name" value="PTHR22888"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00116">
        <property type="entry name" value="COX2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06481">
        <property type="entry name" value="COX_ARM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000292">
        <property type="entry name" value="Ubi_od_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="SSF49503"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81464">
        <property type="entry name" value="SSF81464"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01433">
        <property type="entry name" value="CyoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50857">
        <property type="entry name" value="COX2_CUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50999">
        <property type="entry name" value="COX2_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 11" id="KW-0249">Electron transport</keyword>
    <keyword evidence="10 11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="7 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 11" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="38"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="83"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="domain" description="COX2_TM" evidence="14">
        <location>
            <begin position="16"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="domain" description="COX2_CUA" evidence="13">
        <location>
            <begin position="128"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR000292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="PRC92753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="348" mass="38417" checksum="9200F23CFE5C5570" modified="2018-07-18" version="1">MKLLNARRGLLLAAALLSGCNTVVLNPSGDMAAQQGHLLIVATLLMLLIIVPVIALTIFYAWHYRKNNTAAKYEPDWDHSTRLELIIWGAPLLIIIALGTITWIGTHTLDPYRKLSRLDAQRPIPANTETLTVEVVALDWKWLFIYPQLGIATVNEIAAPVDVPIEFKITASSIMNSFFIPALAGQIYAMPGMQTRLNAVINQPGEFDGFSANYSGAGFSDMKFKFHGMTHADFDLWVQKIKAGTETAGVKVDSKLDRSVYAQLEQPSTRDPIRHFSSVDADLYHGILNRCLAEGSICMDEMMTMHHKMSSTKGPDAMKLALLRKNGFVNEICTTAPIASEGNNVRSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYU3</accession>
    <name>A0A2S9GYU3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2556</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92826">
        <property type="protein sequence ID" value="PRC92826"/>
        <property type="gene ID" value="S2091_2556"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="142"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="144"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="176" mass="18821" checksum="3240C2C410BDC96E" modified="2018-07-18" version="1">MNKMSLLLIVTTLGINYHNTQAQTSPDALLDLSKDISIETGEIPGFFSSPPGVDMLKNAIKNRDGSKTIKAGKQVPEANELNRKICESMGMKDVTNESDFTLGSGALFGGACSGTDVSRKLSTRAQPVPGKVGGRIFIPIPENDLTQSKPQPTMQYSPRAPTQIIPYPTTGSTPLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYW1</accession>
    <name>A0A2S9GYW1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative O-methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_2318</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92901">
        <property type="protein sequence ID" value="PRC92901"/>
        <property type="gene ID" value="S2091_2318"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008171">
        <property type="term" value="F:O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002935">
        <property type="entry name" value="SAM_O-MeTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01596">
        <property type="entry name" value="Methyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51682">
        <property type="entry name" value="SAM_OMT_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC92901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="219" mass="24210" checksum="725846493D0F3226" modified="2018-07-18" version="1">MSNKTLNLNETLYQYILDHSIREHPAQTALRAATDTHPYAQMQISPEQGQFMAMLVKLLGARRTIEIGVFTGYSALSVALALPDDGKLLACDISDEYTRIGKPFWEQAGVAHKIDLQLAPAQRTLDARISAGESGQYDFAFIDADKCSYDGYYESCLQLLRKGGLIAIDNTLWSGKVAAPSTSDDTTALQKFNIKLHRDERIDLSLLPISDGLTLALKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYZ9</accession>
    <name>A0A2S9GYZ9_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="14 15">Protein translocase subunit SecA</fullName>
            <ecNumber evidence="14">7.4.2.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">secA</name>
        <name evidence="19" type="ORF">S2091_2586</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="14">Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="14">Cell membrane</location>
            <topology evidence="14">Peripheral membrane protein</topology>
            <orientation evidence="14">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="14">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="14">Distribution is 50-50.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 14 15">Belongs to the SecA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.4.2.8" evidence="14"/>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92856">
        <property type="protein sequence ID" value="PRC92856"/>
        <property type="gene ID" value="S2091_2586"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0065002">
        <property type="term" value="P:intracellular protein transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017038">
        <property type="term" value="P:protein import"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006605">
        <property type="term" value="P:protein targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd18803">
        <property type="entry name" value="SF2_C_secA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01382">
        <property type="entry name" value="SecA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004027">
        <property type="entry name" value="SEC_C_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000185">
        <property type="entry name" value="SecA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020937">
        <property type="entry name" value="SecA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011115">
        <property type="entry name" value="SecA_DEAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014018">
        <property type="entry name" value="SecA_motor_DEAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011130">
        <property type="entry name" value="SecA_preprotein_X-link_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044722">
        <property type="entry name" value="SecA_SF2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011116">
        <property type="entry name" value="SecA_Wing/Scaffold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036266">
        <property type="entry name" value="SecA_Wing/Scaffold_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036670">
        <property type="entry name" value="SecA_X-link_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30612">
        <property type="entry name" value="PTHR30612"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02810">
        <property type="entry name" value="SEC-C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07517">
        <property type="entry name" value="SecA_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01043">
        <property type="entry name" value="SecA_PP_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07516">
        <property type="entry name" value="SecA_SW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00906">
        <property type="entry name" value="SECA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00957">
        <property type="entry name" value="SecA_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00958">
        <property type="entry name" value="SecA_PP_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81767">
        <property type="entry name" value="SSF81767"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81886">
        <property type="entry name" value="SSF81886"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00963">
        <property type="entry name" value="secA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01312">
        <property type="entry name" value="SECA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51196">
        <property type="entry name" value="SECA_MOTOR_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 14 15" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 14" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 14" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="13 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 14 15" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10 14 15" id="KW-0653">Protein transport</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11 14" id="KW-1278">Translocase</keyword>
    <keyword evidence="12 14 15" id="KW-0811">Translocation</keyword>
    <keyword evidence="3 14 15" id="KW-0813">Transport</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="SECA_MOTOR_DEAD" evidence="18">
        <location>
            <begin position="1"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="16">
        <location>
            <begin position="87"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="17">
        <location>
            <begin position="440"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="85"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <begin position="103"/>
            <end position="107"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="514"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU003874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="PRC92856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="916" mass="103391" checksum="F153E604BBB361E8" modified="2018-07-18" version="1">MSILTQIFGSRNQRLLKQYQSTVRVINALEPVLEALSDTELKAKTAEFKARIEQGSTLDQLLPEAFAVCREASKRALKMRHFDVQLIGGMVLHYGKIAEMGTGEGKTLMATLPAYLNALSGKGVHVVTVNDYLAQRDAEWMDQLYSWLGLTTGVNLSQMDHDTKQAAYAADITYGTNNEFGFDYLRDNMVYEASERVQRPLNFAVVDEVDSILIDEARTPLIISGQAENHTDLYYKINEVPKLLTLQIGDETPDGKGKVDVPGDYTKDEKSHQVLLTEAGHERAEQILTQMGLLPEGASLYDAANITLIHHLYAALRAHALYFKDQHYVVQNNEVVIVDEFTGRLMTGRRWSEGLHQAVEAKEGVKIQNENQTLASITFQNYFRMYTRLSGMTGTADTEAYEFQEIYKLETVVVPPNRPSKRVDRQDQVYKSSEEKYNAMLIDIKDCCERGQPVLVGTTSIENSELLSGILTKAKLAHNVLNAKQHAREAEIIAQAGRPKMITIATNMAGRGTDIVLGGNVEKQIQLIEANPDLSEGQKQQQSQKLRDEWQSLHDHVVAAGGLHIVGTERHESRRVDNQLRGRSGRQGDPGSSRFYLCLDDSLLRIFAGDRVRAIMDRLKMPEGEPIEAGIVSRSIESAQRKVEARNFDIRKQLLEYDDVSNDQRKVIYQQRNELLETTDISEMIASLRGAVFHDIVRTYVPAESVEEQWDVKALEATLATEWQLDLPLQQMLKDEPDLTDEDLLEKVQAAANQVYDAKIAIVGRESFGRFERSVTLQSVDTHWREHLAALDHLRQGIHLRGYAQKNPKQEYKRESFELFAQMLEMIKNDVTKTVMVVRIQSREEIEAVEPDQLANVHYQHADFDANAAPEELFSPTAEPEDHNQPHVNHALKVGRNDPCPCGSGRKFKMCHGRLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZ40</accession>
    <name>A0A2S9GZ40_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Response regulator receiver domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2385</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92968">
        <property type="protein sequence ID" value="PRC92968"/>
        <property type="gene ID" value="S2091_2385"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="4"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="121" mass="13148" checksum="CA506A8A8278FE73" modified="2018-07-18" version="1">MEKTILAVDDSGSLRQMLSFSLKAAGYQVIEAVDGQDGLDKARLQVVDLVLTDQNMPRMDGLTLIKALRAMPSYQQVPILMLTTESGDDMKAKGRAAGANGWLVKPFDPQKLTDVVKKVIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZH5</accession>
    <name>A0A2S9GZH5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Putative metalloendopeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">S2091_2225</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93139">
        <property type="protein sequence ID" value="PRC93139"/>
        <property type="gene ID" value="S2091_2225"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08662">
        <property type="entry name" value="M13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1380.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000718">
        <property type="entry name" value="Peptidase_M13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018497">
        <property type="entry name" value="Peptidase_M13_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042089">
        <property type="entry name" value="Peptidase_M13_dom_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008753">
        <property type="entry name" value="Peptidase_M13_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11733">
        <property type="entry name" value="PTHR11733"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01431">
        <property type="entry name" value="Peptidase_M13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05649">
        <property type="entry name" value="Peptidase_M13_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00786">
        <property type="entry name" value="NEPRILYSIN"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51885">
        <property type="entry name" value="NEPRILYSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015419576" evidence="8">
        <location>
            <begin position="25"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M13_N" evidence="10">
        <location>
            <begin position="55"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M13" evidence="9">
        <location>
            <begin position="486"/>
            <end position="687"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF05649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC93139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="690" mass="76368" checksum="2CEE51C8871E9C2D" modified="2018-07-18" version="1">MKQLTKRFALSAIVLALSSASLYAATPATAETTSSVAALPSGIEKANIDGTVRIQDDFYRHVNGTWLKTTEIPADKSRWGSFNVLADAVLPQMQGIIETLSKDPNIAPGTDAQKVSDLYASYMDTTTIDALGLKPLDATFAQIDAVSDKNQIPTLIAYLNRVGITAPYGFGIHQDAKDSTKYIVDLGQSGLGLPDRDYYLKDDDAKLKSARDAYQKHIEKMLGMAGDAKAADSAAAIIKLETALAQVQWSKVEQRDPVKGYNKIELAKLNALTPDHDFLSYLKAVGVDGKITYVIVSQPSYFTGFAKVMQDTPLATWKTYFKWHALSDNSSLLPANFADEHFAFYSTTLRGVPQQEVRWKRGVRMADGDMGEALGKIYVSKYFPPEYKARMEKLVDNLLAAYKQSVTKLDWMSPATKKEAQAKLATFMPKIGYPSKWRDYSALTIKKDDLIGNSMRANEFATQFEINKLGQPIDRAEWGMTPQTVNAYYNPELNEIVFPAAILQPPFFNANADDAVNYGAIGAVIGHEISHGFDDQGSQYDEKGNLRDWWTKQDHKKFAAKTAALVKQYNSFSPLPGYFVNGELTLGENIADNSGLAIAFKAYKISLNGKPAPVIDGFTGEQRFYMGFGQVWQSKSRDAATLVQIKTDPHSPAEFRGNGTVQNQPEFYKAFDVKKGDKMYVAPANRVIIW</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZJ4</accession>
    <name>A0A2S9GZJ4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">FimV N-terminal domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_2241</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93155">
        <property type="protein sequence ID" value="PRC93155"/>
        <property type="gene ID" value="S2091_2241"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00118">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.2200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038440">
        <property type="entry name" value="FimV_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036779">
        <property type="entry name" value="LysM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020011">
        <property type="entry name" value="Motility_prot_FimV_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020012">
        <property type="entry name" value="Motility_prot_FimV_N"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03505">
        <property type="entry name" value="FimV_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03504">
        <property type="entry name" value="FimV_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51782">
        <property type="entry name" value="LYSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015733521" evidence="3">
        <location>
            <begin position="23"/>
            <end position="910"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="4">
        <location>
            <begin position="187"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="136"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="378"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="781"/>
            <end position="807"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="328"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC93155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="910" mass="97143" checksum="A9A3DE452CF6F1A3" modified="2018-07-18" version="1">MGVKTFSLALASSCLIYSGADAAGLGKLTVLSALGQPLRAEIELTSVTQDDAGNLVPKLASAEAFKQANIDFNSNLLSLRFAVEERGSRHFVLVTSTQSVNEPFVEILLELNSSSGKLIREYTMLIDPLEMQANNSATSVSSGSASRSSLTSTPITPSSTTTTAKSAEHASNVVVNKNAGPAGDKGASYQIKAGDTLGKIADKFKPQGVSLDQMLVALHRNNSSAFINDNMNLLRSGRILSIPDTAEVERTSQSEAKKIILAQSVDFNTYRNKVANQVAQAQPEKAVETKKTDSGKITAKVTEAPTPINESKDKLKLSKAQMQDQADKKALEEDKIAKQKALDVANARVKELEQNTAKLQSILDLKNKTAPVAAPVKNVEPDHSASTPALAPAPTTASAPASLPAIEASVPASMPAHKPVRPRVQAAPVPEPTPGFFDGWLKYLPYGAGVLALLGVAGIYSSKRKKKPEHFDDESILTGSSMKANSLFGSTGGQSVDTNNSVFNSNFAPSASQLDANEVDPVAEADVYIAYGRDEQAEEILKEALRTQPDRQAVRVKLLEIYAHRKDTRTFETVASELYGMTGGAGADWAQAASLGIIIDPQNPLYAGGLAAEHSSVLGASTLPIESLDPEALLGNSLSQQMLDSISAKHDSSHSLMLGDINDRTHRTDELDDGLDFDLGLTTAAVPENEFKSSFSSTPVKEDAPTIAMPAHEAKESFDMADFAVALPPETPAEEIIPMIPTKTAPAAHVQPDAEEIGMDFAALDFDFDIPKSKPEEVVQVETHTHHDDDMSMLEMPTSHQPEQAAPSFDFDLSDIDLELPKVATEAHHAEPSFAQASPVESKHDAAPQAPVEIVSEAEYSAEMATKLDLAVAYQEIGDKDGARELLDEVLKGGNPEQIARAKAMMHEMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZN3</accession>
    <name>A0A2S9GZN3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1933</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93195">
        <property type="protein sequence ID" value="PRC93195"/>
        <property type="gene ID" value="S2091_1933"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015537469" evidence="1">
        <location>
            <begin position="39"/>
            <end position="444"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="444" mass="48417" checksum="DEE19CC0EC6796E0" modified="2018-07-18" version="1">MNSIIFSSIRLRKGFNKLRLIALITLCSNLLTPLIAHAVPAYARQTGQNCVACHAGGQFPELTPYGRLFKLTGYTIGSRTIPVSVMGVASLTKSLHPDSDPTFAKDAVAIFQTGSVFLAGKVTDNIGIFAQATYNNYGGDSGYQGVWGSDNFDLRYADRLIDTNNDLIFGVTLNNNPSVSDPWNSAPAWIIYAPTQFGVTTPDAAPIVSSLGAQVAGINAYALWNNLLYAEVGGYQTANGVWSFLSKGTSDENQTKLSGTNPYIRVALTHEWGAHNVMLGMFGLNANIYPDNTNPSGPTIQYHDRGVDAQYQYLLDPHTASAQFSYIKETINNGDVTGIATNPSNTLRQLRMKGTYIYQAKYGGSLSYFSTTGTSDPTLYSNPTANPDTRGWTPEVFWTPIQNIRIGLQYYAFQRFDGASNNYDGAGRNAKDNNTAFLYVWGAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZY6</accession>
    <name>A0A2S9GZY6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2037</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93299">
        <property type="protein sequence ID" value="PRC93299"/>
        <property type="gene ID" value="S2091_2037"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="117" mass="13226" checksum="32106762EAEEB2E6" modified="2018-07-18" version="1">MIYEIQIRATGSKQYSPQSLSQSSSEQLIWVESSLPTRAFEQWLVKRNLLNFLGNGAVARWSIVQTKRPAHFVLDSEERALEQRIAALMHPTSVVKKVPAITKAHRDLHLSEFALAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H003</accession>
    <name>A0A2S9H003_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2035</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93297">
        <property type="protein sequence ID" value="PRC93297"/>
        <property type="gene ID" value="S2091_2035"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009593">
        <property type="entry name" value="DUF1203"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06718">
        <property type="entry name" value="DUF1203"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF034110">
        <property type="entry name" value="DUF1203"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="165" mass="18627" checksum="DD8A9885187BDA19" modified="2018-07-18" version="1">MSFRILGLAPDQFQPLFSLSDAELEKIGARRLFADEPGMPCRVSMAHAELGEELLLLNFEHQPANTPYRATHAIYVRKLAKHAFTTVDSVPEILATRLLAVRAYNAEHMMIDAEIVEGILVTELFERFFADPQTSYLHVHNARRGCYAGRVERYDGDGSKGKYTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H004</accession>
    <name>A0A2S9H004_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2057</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93319">
        <property type="protein sequence ID" value="PRC93319"/>
        <property type="gene ID" value="S2091_2057"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="126" mass="13814" checksum="37335069B12DC661" modified="2018-07-18" version="1">MIKTILVIGGTAFEREVAITNALATSSEPDFKKSAVLLEGLADGKTTLLSDTNTIISRIASGCLCCGNNMIMRVYLNRLIQQNPHQLFLSLSTAEHLEQVKLFLTTPSYKKILELSTELNLNSINS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H059</accession>
    <name>A0A2S9H059_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1994</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93256">
        <property type="protein sequence ID" value="PRC93256"/>
        <property type="gene ID" value="S2091_1994"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015678342" evidence="1">
        <location>
            <begin position="21"/>
            <end position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="418" mass="46718" checksum="F963A77144431C4B" modified="2018-07-18" version="1">MTKKIVLIFSALFLCSSLFAQEHMSPRQWANAADVANSKKDYPTAIADYQQAINGGYSNFGLLYSLACVYSLQNNSEQALLALEKSAAMGLRSASILQNESDLNPLHSDPHWAKIVAIVTKNEQAYHVTHNDPNGFKFVTSDIDLFWKTYDQLPTAADPALLWERNYLDRGTVGLQGFIFSRIQSGEFLNKMIQSESKFYAGIRKNTLQTASVEPRVRTALRKFKSLYPEANFPDVYFVIGNSGTGGTSTNDGLVVGTEIFSLSADVPIDELNDWQKSVIKTPDLLPSIVIHELMHFQQNYDSPEMLASVIKEGAADFLASLVVDGNFNQRIYDYGYVHEAELKQQFLLDMKKNDATHWLYNGGSAKGSPADLGYFMGFRITQAYYQRATDKKQAVVDILNINDFNAFVAQSGYFDGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H092</accession>
    <name>A0A2S9H092_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Phosphate acetyl/butaryl transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">S2091_1760</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the malic enzymes family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">In the N-terminal section; belongs to the malic enzymes family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93373">
        <property type="protein sequence ID" value="PRC93373"/>
        <property type="gene ID" value="S2091_1760"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004471">
        <property type="term" value="F:malate dehydrogenase (decarboxylating) (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006108">
        <property type="term" value="P:malate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05311">
        <property type="entry name" value="NAD_bind_2_malic_enz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10750">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10950">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminiacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012301">
        <property type="entry name" value="Malic_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037062">
        <property type="entry name" value="Malic_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012302">
        <property type="entry name" value="Malic_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045213">
        <property type="entry name" value="Malic_NAD-bd_bact_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001891">
        <property type="entry name" value="Malic_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012188">
        <property type="entry name" value="ME_PTA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042113">
        <property type="entry name" value="P_AcTrfase_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042112">
        <property type="entry name" value="P_AcTrfase_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002505">
        <property type="entry name" value="PTA_PTB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00390">
        <property type="entry name" value="malic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03949">
        <property type="entry name" value="Malic_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01515">
        <property type="entry name" value="PTA_PTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036684">
        <property type="entry name" value="ME_PTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00072">
        <property type="entry name" value="MALOXRDTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01274">
        <property type="entry name" value="malic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00919">
        <property type="entry name" value="Malic_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="SSF53223"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="9" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="malic" evidence="12">
        <location>
            <begin position="24"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="domain" description="Malic_M" evidence="11">
        <location>
            <begin position="169"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="100"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="82"/>
            <end position="89"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="142"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="143"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="168"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="293"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR036684-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR036684-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR036684-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003427"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM01274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PRC93373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="766" mass="83666" checksum="99FFC66D03144C59" modified="2018-07-18" version="1">MDTHSDKAEQLRCAALEYHEHPIPGKISVTATKQLTNQRDLALAYSPGVAAPCEEIVKDPANVFKYTARGNLVGVITNGTAVLGLGNIGPLASKPVMEGKGVLFKKFAGIDVFDIEINESDPDKLCDIIASLEPTFGGINLEDIKAPECFYIERKLRDRMKIPVFHDDQHGTAIIVGAAILNGLKVVNKDIKKCKLVVSGAGAAALACLDLIVDLGFPIENIFVTDLAGVVYKGRTELMDPDKARFAQDTSARTLAEIIPGADVFLGLSAAGVLKKDMVKQMGERPLVMALANPTPEILPEEVREVRSDAIIATGRSDYPNQVNNVLCFPYIFRGALDCGATTITREMEIAVVHAIAELAQAEQSDVVATVYGFTNLSFGPEYLIPKPFDPRLMMKIAPAVAKAAFESGVATRPIADLEAYAEKLQQFVYHSGTFMKPAFQIAKNAADTKKRIVFAEGEDERVLRAVQIIVDEHLAKPILVGRPSVLDKRIEKFGLRIRAGVDFEVINPEFDERYRDYWETYYELTARQGVTQQYAKLEMRRRHSLIGAIMIKKGHADGMICGTFGTTHLHLKYIDQVLGKREGVNVYAAMNALILPDRQIIMVDTHVNENPNAEQMAEITILAAEEMRRFGITPHVALLSHSNFGSSNSESAQKMRDALAIIRRDAPDLEVDGEMHGDSALDSAYRKKSMPSSTLKSNANLLVLPNIDAANISYNLIKIAAGNGIAIGPILLGCAKPVHILTPSATVRRIVNMTALCVVDAVAQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0A7</accession>
    <name>A0A2S9H0A7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1798</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93411">
        <property type="protein sequence ID" value="PRC93411"/>
        <property type="gene ID" value="S2091_1798"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="32" mass="3438" checksum="A5C9F8D27B2931B5" modified="2018-07-18" version="1">MNQTNNVGFRVLARDIAEELTAEELMDVSGGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0A9</accession>
    <name>A0A2S9H0A9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">40-residue YVTN family beta-propeller repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1802</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93415">
        <property type="protein sequence ID" value="PRC93415"/>
        <property type="gene ID" value="S2091_1802"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011048">
        <property type="entry name" value="Haem_d1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019405">
        <property type="entry name" value="Lactonase_7-beta_prop"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011964">
        <property type="entry name" value="YVTN_b-propeller_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10282">
        <property type="entry name" value="Lactonase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51004">
        <property type="entry name" value="SSF51004"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02276">
        <property type="entry name" value="beta_rpt_yvtn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015423438" evidence="1">
        <location>
            <begin position="28"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="332" mass="35573" checksum="9BD0FD9EB4D9DB31" modified="2018-07-18" version="1">MLNIKYVTTILFSFGIAVANIQTSANAADQKWTFDGAIHNNSLAVSPDETMAVASYSERQEIVVYDLKSKSVRKILRGYITPRNSVFDPSGKAFYVSDSSLGVIKKIDATSLEEIGQFAAGPGVFGTTISADGKTLYANNEAANTVTSFNLNTNQPTAVIPGFSQPRQGVRLNPNGDTLFVTNFLGDKITLVNTKTNQIDGEIAGFNKIRAISISHDGKTLYAANSGSNMIAVVNIADRKITSMIPVGKDPYGAALTPDGKFLYSGNLADNSLTVISLPSEHVVASVDGLKQPRQAIVFSHNSKLAYVLNEDLSVAIINLDNNKIAEVILPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0D2</accession>
    <name>A0A2S9H0D2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1831</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93444">
        <property type="protein sequence ID" value="PRC93444"/>
        <property type="gene ID" value="S2091_1831"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011747">
        <property type="entry name" value="CHP02241"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010667">
        <property type="entry name" value="Phage_T4_Gp19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38009">
        <property type="entry name" value="PTHR38009"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06841">
        <property type="entry name" value="Phage_T4_gp19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02241">
        <property type="entry name" value="TIGR02241"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="155" mass="17290" checksum="DCB5AE5224EBE356" modified="2018-07-18" version="1">MSADYFEGGYPPPAFYFTVTFGDGVKMPDASFSEVSGISIEMETEPLVEGGENRFVHQLPKSIKHPNLELKRGVSMLNSPLVKWCKDTLEGAFIKAIVPNTIIVKLNGADGQVLRAWAFIDAYPIKWDVEGFNATKNEVAIEKMTFAYTYSKRSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0E9</accession>
    <name>A0A2S9H0E9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Acetyl-CoA carboxylase carboxyltransferase component (Subunits alpha and beta)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2074</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93336">
        <property type="protein sequence ID" value="PRC93336"/>
        <property type="gene ID" value="S2091_2074"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034733">
        <property type="entry name" value="AcCoA_carboxyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011763">
        <property type="entry name" value="COA_CT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011762">
        <property type="entry name" value="COA_CT_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045190">
        <property type="entry name" value="MCCB/AccD1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22855">
        <property type="entry name" value="PTHR22855"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01039">
        <property type="entry name" value="Carboxyl_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50989">
        <property type="entry name" value="COA_CT_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50980">
        <property type="entry name" value="COA_CT_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="CoA carboxyltransferase N-terminal" evidence="1">
        <location>
            <begin position="21"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="domain" description="CoA carboxyltransferase C-terminal" evidence="2">
        <location>
            <begin position="280"/>
            <end position="526"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="534" mass="57729" checksum="0544DFADEBE9E4FA" modified="2018-07-18" version="1">MKLESKLAPRSEEFKANVAAMQVVVDDLKNKIEKILLGGGDDARKKHLARGKLLPRDRVQMLLDPGTPFLEFSQLAAFEMYHNAAPCAGVITGIGRISGQECVIVCNDATVKGGTYYPLTVKKHIRAQEIAEQNNLPCVYLVDSGGANLPNQDEVFPDRDHFGRIFFNQANLSAQGIPQIAVVMGSCTAGGAYVPAMSDESIIVKNQGTIFLGGPPLVKAATGEVVSAEDLGGGDVHTRLSGVVDHLAQNDMHALSMARTIVANLNRQKPSQLKLQEVVEPAYPAQELYGVIPVDTRKPFDVREVIARVVDGSVFDEFKARYGTTLVCGFAHIHGMPVGIIANNGILFSESALKGTHFIELCCQRKIPLVFLQNITGFMVGRKYENEGIARNGAKMVTAVATAAVPKFTVIIGGSFGAGNYGMCGRAFSPRFLWMWPNARISVMGGEQAASVLATVKRDGIEAKGGAWSAEEEAQFKQPIKEQYEHQGHPYFASARLWDDGVIDPADTRMVLGLGLSAALNAPIPETKFGLFRM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0H2</accession>
    <name>A0A2S9H0H2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1845</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93458">
        <property type="protein sequence ID" value="PRC93458"/>
        <property type="gene ID" value="S2091_1845"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019660">
        <property type="entry name" value="Put_sensory_transdc_reg_YbjN"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10722">
        <property type="entry name" value="YbjN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="293" mass="33295" checksum="476FA8AA37DAC100" modified="2018-07-18" version="1">MTTIDSSIFFHSKSLIANFHLCELTYQQAEGKHNGISLKLRADHASYEKIETAAFFNNALENRLDIVEGGFNPDLNVFINIDLRQEHVHLLPTDQCDLTHYFQHMSKDDPLLQENFWNATFVWTEIHLSPTIGGGVIKVGYKTRFSTPANRIDLIKRQGSVSKAITTALIENNFPVYFDDASQCFALILKMEDAHYHTTITPDNQHSAMSIQLAYTIDIPPHKETQAIDLLSDINKEIIFGEFFIEKQKLTYCHAIQVAEELISDQWVSGALLASGSVMHHYAKKLEELIGQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0N3</accession>
    <name>A0A2S9H0N3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyl transferase family 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1546</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93545">
        <property type="protein sequence ID" value="PRC93545"/>
        <property type="gene ID" value="S2091_1546"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="2">
        <location>
            <begin position="7"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="387" mass="44660" checksum="B4CA98CE7F228A8F" modified="2018-07-18" version="1">MTSPLVSVIMATYNHADFVKQAIESVLAQQGVDFEFLIADDGSFDRTREVVASIKDQRIQFFPNEVNRGACVVTNELIERASGEFIALINSDDSWIGSDKLAYQVQILRNNPLIGACFGRAKFIDKTGESIGKETLPFGSVFDQENRTQGQWLRRFFDLGNCICHPTMLIRKTCYNELGMYNNRLRQLPDFEMWIRLIKYYEIFISDRELINFRILPGENASSQTEVNSTRTINEHFLIAEDFFEHVTREQLIDGFSDLLVVKNLPSDEHLEIEKGLLFLRENQWLGKPYKLVGLLHMFKILGLEKCYDVMVTAYRIDDRWFQQQMGEIGTLNRTIIERAVNLGERINSATNMGFFNGLQLKFFLKFVSAKLLSVNQVLKSLNNRRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0W7</accession>
    <name>A0A2S9H0W7_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">Alanine dehydrogenase</fullName>
            <ecNumber evidence="2 5">1.4.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">S2091_1609</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>H2O + L-alanine + NAD(+) = H(+) + NADH + NH4(+) + pyruvate</text>
            <dbReference type="Rhea" id="RHEA:18405"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="EC" id="1.4.1.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the AlaDH/PNT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.4.1.1" evidence="2 5"/>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93608">
        <property type="protein sequence ID" value="PRC93608"/>
        <property type="gene ID" value="S2091_1609"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000286">
        <property type="term" value="F:alanine dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042853">
        <property type="term" value="P:L-alanine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05305">
        <property type="entry name" value="L-AlaDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008141">
        <property type="entry name" value="Ala_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008143">
        <property type="entry name" value="Ala_DH/PNT_CS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007886">
        <property type="entry name" value="AlaDH/PNT_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007698">
        <property type="entry name" value="AlaDH/PNT_NAD(H)-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42795">
        <property type="entry name" value="PTHR42795"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01262">
        <property type="entry name" value="AlaDh_PNT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05222">
        <property type="entry name" value="AlaDh_PNT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000183">
        <property type="entry name" value="Alanine_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01002">
        <property type="entry name" value="AlaDh_PNT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01003">
        <property type="entry name" value="AlaDh_PNT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00518">
        <property type="entry name" value="alaDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00837">
        <property type="entry name" value="ALADH_PNT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 8" id="KW-0520">NAD</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AlaDh_PNT_N" evidence="10">
        <location>
            <begin position="4"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="AlaDh_PNT_C" evidence="9">
        <location>
            <begin position="149"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="6">
        <location>
            <position position="96"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="6">
        <location>
            <position position="270"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="15"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="75"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="134"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="198"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="203"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="220"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="239"/>
            <end position="240"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="267"/>
            <end position="270"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="298"/>
            <end position="301"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR000183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000183-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000183-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000183-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM01003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC93608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="370" mass="38774" checksum="131A36F31A73D74A" modified="2018-07-18" version="1">MLIGVPKEIKNHEYRVGLTPASVRELCLRGHKVIVQSDAGTAIGLLDTDYQAAGAEMVAGAAEIFKRADMIVKVKEPQPVECAMLRPGQILYTYLHLAPDPEQTKALIASGAICFAYETITGPGGGLPLLAPMSEVAGRMSIQAGAAHLEKSKGGMALLLGGVPGVAPGHVVILGAGVVGTSALQVAVGVGARVTILDKNIDRLRHLDLIYGNRISTLYSNAQTVEDSVLAADLVIGGVLIPGAAAPKLVTRDMIKKMKPGAVVVDVAIDQGGCFETSHATTHAEPTYIVDHVVHYCVANMPGAVARTSTFALNNATIRHALALADKGWKLACKEDVHLKNGLNVCQGKVTYEAVARELGIEYVAADSLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H151</accession>
    <name>A0A2S9H151_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative translation initiation inhibitor yjgF family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1713</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93712">
        <property type="protein sequence ID" value="PRC93712"/>
        <property type="gene ID" value="S2091_1713"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06150">
        <property type="entry name" value="YjgF_YER057c_UK114_like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035959">
        <property type="entry name" value="RutC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006175">
        <property type="entry name" value="YjgF/YER057c/UK114"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035709">
        <property type="entry name" value="YoaB-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47328">
        <property type="entry name" value="PTHR47328"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01042">
        <property type="entry name" value="Ribonuc_L-PSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55298">
        <property type="entry name" value="SSF55298"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="121" mass="13210" checksum="B50C766D7FD799B5" modified="2018-07-18" version="1">MNITRYEMGPRFSEMTVVDLGTAKLIYLAGQVAQNTSLDVSGQTREVLQYIDQLLAKAGATKTDIVAARIYLGSTGDYAVMNAIWDDWVVPGHTPARTTVGSRLVNLEYKVEIEVTAAINS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1H7</accession>
    <name>A0A2S9H1H7_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_1427</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93818">
        <property type="protein sequence ID" value="PRC93818"/>
        <property type="gene ID" value="S2091_1427"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="7"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="145"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="8">
        <location>
            <begin position="164"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="7">
        <location>
            <begin position="224"/>
            <end position="433"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC93818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="433" mass="48294" checksum="F7A2AFC94ADBA466" modified="2018-07-18" version="1">MNRLLPRFILLVLLSVTVASVAVYFAISYWFGDPLEEIARKQSAAQIFLLEQFVDKAPTDEWLVRLNKVREVSNIKLELVPLNSVVLSAVKTKQLLKGEVVLDVPGKAFYRRVDQDGERYIGSAEDVIHVQGLPINVGLTLQMEAFRYAIVALFLLIPIVFWSRAHWRALQSLSTAADQFGEGQFGKKIVMHENATMYPLAQCMNLMAERIENLLSAHRTLLHSVSHELRTPIARLGFGLELLREESGGDQSRIQAMEADIDELNALVNELLNLTKLDHQQSLKAASFSVQNMLEELKNTALYSLNGKQCSIRYADNLGTIIADQRILTRALSNLIFNAVKYGNQQILISAHALSDGAIEFAVEDDGPGIPPNERVRVFEPFYRLDQSRDRSTGGFGLGLAIAQKAVQLHGSTIQISESALSGAKFYFVIARQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H202</accession>
    <name>A0A2S9H202_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ABC-type transport system involved in resistance to organic solvents auxiliary component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1187</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94014">
        <property type="protein sequence ID" value="PRC94014"/>
        <property type="gene ID" value="S2091_1187"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008869">
        <property type="entry name" value="MlaC/ttg2D"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36573">
        <property type="entry name" value="PTHR36573"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05494">
        <property type="entry name" value="MlaC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004649">
        <property type="entry name" value="MlaC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015506389" evidence="1">
        <location>
            <begin position="25"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="213" mass="23689" checksum="CCC87BEF5E49F99C" modified="2018-07-18" version="1">MNMLKKIFVSLIASSALCLGVAHAAEEAPDVLVKRISQEVLDVAKSDKDIQAGNQQKILDLVEQKILPYVDFQRMTELAAGRNWRVATPAQQQELVKQFRSLLIYTYSGALSQVKDQKIEYRPFRADPADTDVEVRSQVVTARVGQAIQLNYRLGKGADGWKIYDINVLGAWLIETYKGNFTAEINKSGIDGLIKTLTDKNAKLAVSFAKKST</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H256</accession>
    <name>A0A2S9H256_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1119</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC93946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93946">
        <property type="protein sequence ID" value="PRC93946"/>
        <property type="gene ID" value="S2091_1119"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021836">
        <property type="entry name" value="DUF3429"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15887">
        <property type="entry name" value="PTHR15887"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11911">
        <property type="entry name" value="DUF3429"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="132"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="152" mass="17188" checksum="4C1EE911170B3588" modified="2018-07-18" version="1">MNHHFLSKRLAHQLGFVGLIPFIILSLACWITHPDWLDGFVYAQSAYGIAILSFLGGIHWGVALTSPELTAEQIKRALIWGVVPTMIAWCSKLNFGFGFFVLMFGFIASYQIDKRLYVTYQMPEWFLVLRRRLTIVVVAALALTVLAVNVRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2A6</accession>
    <name>A0A2S9H2A6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative membrane protein (DUF2306)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1287</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94114">
        <property type="protein sequence ID" value="PRC94114"/>
        <property type="gene ID" value="S2091_1287"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018750">
        <property type="entry name" value="DUF2306_membrane"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10067">
        <property type="entry name" value="DUF2306"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="46"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="85"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="114"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="148"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="174"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="209" mass="23438" checksum="66D9FFEC203CC8E5" modified="2018-07-18" version="1">MKLMLRKSLWSLMLLLAVGVAAYTIHLLFWSTHVPPFLRERLASHAPSLYFHLLGGSAAIVLGALQMNMRLRKKFTAFHRWTGRVYLLAVLMSGTAGLEMSVVATGGWVAKSGFATMALLWLATGLLAYLAIRKGDIAAHRNWMMRNYSLTLAAITLRVYLGITFGLLQMDFMQVYPIISWACWVPNLLFAQWFFVNPIPRSSISNAVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2M0</accession>
    <name>A0A2S9H2M0_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Disulfide bond formation protein B</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">Disulfide oxidoreductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="primary">dsbB</name>
        <name evidence="17" type="ORF">S2091_0856</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="15">Cell membrane</location>
            <topology evidence="15">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 15">Belongs to the DsbB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94235">
        <property type="protein sequence ID" value="PRC94235"/>
        <property type="gene ID" value="S2091_0856"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015035">
        <property type="term" value="F:protein-disulfide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00286">
        <property type="entry name" value="DsbB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003752">
        <property type="entry name" value="DiS_bond_form_DsbB/BdbC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022920">
        <property type="entry name" value="Disulphide_bond_form_DsbB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023380">
        <property type="entry name" value="DsbB-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02600">
        <property type="entry name" value="DsbB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158442">
        <property type="entry name" value="SSF158442"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="5 15" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="13 15" id="KW-0143">Chaperone</keyword>
    <keyword evidence="12 15" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8 15" id="KW-0249">Electron transport</keyword>
    <keyword evidence="11 15 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="10 15" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14 15" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 15 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 15 16" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 15" id="KW-0813">Transport</keyword>
    <feature type="topological domain" description="Cytoplasmic" evidence="15">
        <location>
            <begin position="1"/>
            <end position="7"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="topological domain" description="Periplasmic" evidence="15">
        <location>
            <begin position="25"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="39"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="68"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="topological domain" description="Periplasmic" evidence="15">
        <location>
            <begin position="82"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="134"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="topological domain" description="Cytoplasmic" evidence="15">
        <location>
            <begin position="156"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="15">
        <location>
            <begin position="34"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="PRC94235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="159" mass="17137" checksum="5BB5C1306C6DDD37" modified="2018-07-18" version="1">MKKTQIALLITAIASLAIVGGALYFQIVERMPPCPLCIIQRYAFILLAIGSLIGMAGPALLRKIGCCLGLYASISGAGVALHQLYVIAHPDIKCGIDPVQTAVNSLPFASWLPTVFSAEGLCGTPYDPFFGLVLPQWSLLWFVVFTVVLLLVLFKSKKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2P8</accession>
    <name>A0A2S9H2P8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="9">TonB-dependent Receptor Plug Domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_0875</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94254">
        <property type="protein sequence ID" value="PRC94254"/>
        <property type="gene ID" value="S2091_0875"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039423">
        <property type="entry name" value="TonB-dep_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32552">
        <property type="entry name" value="PTHR32552"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="3 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0675">Receptor</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0798">TonB box</keyword>
    <feature type="domain" description="Plug" evidence="8">
        <location>
            <begin position="123"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="7">
        <location>
            <begin position="356"/>
            <end position="896"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="82"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="83"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC94254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="902" mass="96325" checksum="C4278319EBC5226F" modified="2018-07-18" version="1">MMKGYTLKSVLHGTKGSRAVASKSMKIRAGAASVIGAVSIFSCGHTFAAEEPPVSDLQAENIRLRKEVEELKKALNPVDASISKADENKTSTVASTPNASAEDNNAPTLDQIVVRAREREENLQDVPIPVSAVSGRMLDRDGAVTIQDFAKLTPNILVQAPNARQTSISIRGVGKNTANDALEPSVGVVIDGVPSAFIAGSWGNFDDLDHIEVLRGPQGTLMGKNTTLGVVNIVTKDPSFKPEATVQLSAGEYDEIGAKATIGGPIQDGVLAYRLSVFSEKRNGPFQDIAPDHTNETFGNRDRAGGRIQFLLLPSPDLSIRLSIDRQRSDEMVPFGDPPLIGEPTTFADGASRTAGSGTTFSSRLSRSYFGDYQPLLGNWNQVVNVGSLPTVSATSGVSANVNWTPFENVTFTSITAYRNSLFDAHNAEWDPFNIRQYGAIIKQEQVSQEFHVNSTVSKTLDYTAGVYFLNSTVDSTDRTLYGSDAGAFYATNAQYNSLSSSGVGTKLLQDSLRGLFVNTTTHPDTKSAAEFGQLNWHFTEQATVTLGLRRTAETKTNNYSNVIEDNSALPSNLQATTLSATGNGVGGQYSGATAAQIAATKGILSAKDVNLGFVNGQDINATSYAWLINPSYKLSENTLLYTSAGYGAKSGAVEFNTTTLTPQNVAPEKALDFELGFKTTQLNHALILGANIYHTKITDYQQNLSVVDPILTAQNQTTTYRTYLGNVAGVTLQGLELDGSYAATERLRFNFSGAYNKAFYSNFADAPCPAEISGAPGGAQQCNFTGKELPFAPRFSTNVGFDYRVPLVGAYYLHTFSNAVYRGSANYNSGLSAVGAQGGYSIIDGGIGIQSPGGKFELTLVGKNLADTHYVTNIDAYSTTSAVTATPGDRRYVGLVLRASI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2V5</accession>
    <name>A0A2S9H2V5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative hydrolases or acyltransferases (Alpha/beta hydrolase superfamily)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0932</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94311">
        <property type="protein sequence ID" value="PRC94311"/>
        <property type="gene ID" value="S2091_0932"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="39"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="290" mass="31938" checksum="86607C495CA3F213" modified="2018-07-18" version="1">MTAKNVDKQVPVATLGEPGFIRTTDNVNLFYRDWGVGETVVFLSGWAMSSDTWCYQMLHLNDQGFRCVAYDMRGHGRSSDPGRGYDFDTMAQDLAAVLNVLELQSVTLVGHSIGCGVITRYLTRYGSGRIKRIAMLGTVTPCMRKAADNPDGVPDEAIDYFLTKQLMQNFPGWIEGSKGPFFGEKTPTGMDTWLTQIALSTSGKALLECSRSLQDADFRKELTNIDVPTLILHGDKDVSAPLELTARRTAALIPGAKLKEYANVAHALFLTDVDRVNADLLEFIGGKKME</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2X4</accession>
    <name>A0A2S9H2X4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0956</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94335">
        <property type="protein sequence ID" value="PRC94335"/>
        <property type="gene ID" value="S2091_0956"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="671" mass="77134" checksum="FCDF2F42F0807C55" modified="2018-07-18" version="1">MQVDIVGRINNLQLPRTQPYIPLFECLVNSIEAMANLPDSSPRRIDVNIEHDIRQQGFKGIEDAASSIQNITITDTGVGFNDANYQAFFLSDSTNKVSNGNKGIGRFTWLKVFEKASVFSTYSDDTEWFQRSFDFLKTKSGVENENISESKSNRYQTIVSLSSLRTEYQKHFPKNLETISRKIIDHLLIYFVSGNCPSIWLHDNLGSSALSVNDMFADEIRSSVTEIPFMVKEWPFMARIVKYHSSTAKQHSVSYCAHQREVRAQKASSLVSDLTVKLLDDDDESFVFLTYISGLYLDENVNSERTDFLFMRDDESDLIEELSKQELYKAVGDQIRSVAAPYLATLKVEKIRNVEQFVANKGPEYRFILNERYETHLDSVPPHLTDDALDLALFKVQREIEVEHREKAKQISTLSTNAVTDSDQYKALYDRYIQEENELGKAALAKYVIHRRTILDLLDKALVFQDDGRYAKEELVHKLIFPMRVTSDDVAFSEQNLWVIDERLAFHIHLGSDVSLKKLKVVNLNDSDEPDIVVFNALTAFSESEQAFQSIVLVEFKRPERNEYPSKDEDPVEQILRYVRKIKDGEAKSIKGKTINGQKIPFYAYIICSLTPKIRQIAADRDFTPTADNEGYFSFHKNSGCYIEILSYDKMLNDAKKRNRAFFDKLQIPFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2X5</accession>
    <name>A0A2S9H2X5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0952</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94331">
        <property type="protein sequence ID" value="PRC94331"/>
        <property type="gene ID" value="S2091_0952"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="95" mass="10413" checksum="5E8C92609439A734" modified="2018-07-18" version="1">MNRDDVEKVGQAALASIELLAADWFPNGVREGREWCIGSREGEAGRSMKICLSGESAGVWKDFSADDTCGDFISLYAYIFRVEEAEAMKALACEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H327</accession>
    <name>A0A2S9H327_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="10">ABC-type transport system involved in lipoprotein release</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">S2091_0999</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94378">
        <property type="protein sequence ID" value="PRC94378"/>
        <property type="gene ID" value="S2091_0999"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025857">
        <property type="entry name" value="MacB_PCD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12704">
        <property type="entry name" value="MacB_PCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="273"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="317"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="369"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="domain" description="MacB_PCD" evidence="9">
        <location>
            <begin position="18"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="8">
        <location>
            <begin position="299"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF12704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC94378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="406" mass="43288" checksum="13D8B3D87DCB9719" modified="2018-07-18" version="1">MMWLSLALRNIVANRRRSMLALAAIAAAAVAMMLFAGYVNAIRVGLRHTTIHDGLGHLRVAAHGGFDAYEEKQLQHGMTPVQYAALEKAADAEPTVRRIVPGLTFQGLVSNGPRTLAFSGSGVDPALESAAFSASHDIVKGAQLNASAPDDGIVLGTELALRLGVEPGQSVTVLTSTVSGAINAADMQVVGIESTGSPERDLHLLRAKLPMVQTLLATDRVSYVALLLDDQADVEDVQRRLSTALPQLELRNWLQLAPYYTQVLGLYENLFRIFGLFILVVSLLGLTTIILTSVLERSREIGVMRALGISAWHVRRAFVLEGLALCVIGVVLGMLVAAGLGESINALRLTMPPPPGQTEGYPLRVLWDWSATAGIATVVLLLGIAAAWMASGRVTRLKVIDALGAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H373</accession>
    <name>A0A2S9H373_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">BenE: benzoate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1055</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94434">
        <property type="protein sequence ID" value="PRC94434"/>
        <property type="gene ID" value="S2091_1055"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042925">
        <property type="term" value="F:benzoate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004711">
        <property type="entry name" value="Benzoate_Transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30199">
        <property type="entry name" value="PTHR30199"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03594">
        <property type="entry name" value="BenE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00843">
        <property type="entry name" value="benE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="56"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="79"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="104"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="129"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="153"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="190"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="273"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="304"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="334"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="396" mass="41058" checksum="E168C3CE978DD1CC" modified="2018-07-18" version="1">MISVIVNYGGTFILVFQAAKIGGLSPELTASWVWSVSIGVGVTGILLSWYTREPIIAAWSTPAAFLVVALATTPYAEAVGAYLISAAAFVVLGLSGYFEKVIRLIPPGIAAGLLAGILLQFGIGAFGGISVDPLLAGILIVTYVVLKRFTARYAVVGILLIGLVFLLIQGRVDLSGLMLEFAAPVFTTPVFSINSLLSVALPLFLITLTGQYMPGMLILRNDGFTTSANPIVAVTGLGSLIMAPFGSHAFNIAAITAAICTGKEAHEDPSKRWIAGIAAGIFYILIGIFGVTLAAVFMAFPTTFITTLAGLALLGTIGGSLASAMSAPESREAALITFLASAANITLFGIGGAFWGLLIGLITYTALNGYLPRNSTLSGETVNLVSTSPNNKGQKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3E5</accession>
    <name>A0A2S9H3E5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Na+/H+-dicarboxylate symporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_0501</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94498">
        <property type="protein sequence ID" value="PRC94498"/>
        <property type="gene ID" value="S2091_0501"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015293">
        <property type="term" value="F:symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3860.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001991">
        <property type="entry name" value="Na-dicarboxylate_symporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036458">
        <property type="entry name" value="Na:dicarbo_symporter_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42865">
        <property type="entry name" value="PTHR42865"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00375">
        <property type="entry name" value="SDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118215">
        <property type="entry name" value="SSF118215"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="7"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="49"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="85"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="154"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="196"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="230"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="326"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC94498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="433" mass="46100" checksum="ADCBBD3CAA345FDB" modified="2018-07-18" version="1">MKKNRSLTMYILLGMILGIVVGYACNEMLPDAKLASTVAGYISIVTDVFLRLIKMIIALLVFSTLTVGIAHMGDAKSVGRIGIKAMGWFVIASLVSLTVGMILSNTMQLGTHLALPLPDVGAATNLKTGSFTLKDFIAHLVPKSPFEAMANNEVLQVVVFSIFFGTALAGLGEAGKKLTTIIDQLAQVMLRITGSIMLMAPVAVFAAMASVVTTQGLGVLVTFAKFMGGFYLGLFILWGLLIAAGFLFLGPRIFKLIKLIREPFLLAFSTASSEAAYPKLLDALDKFGVKRQISSFVLPMGYSFNLDGSMMYCTFAVLFIAQAYGIDMPIGMQITMLLLLMLTSKGMAGVPRASLVVIAATLNHFSIPEAGLLLIMGVDQFLDMGRSATNAVGNSVAAAVIAKWENGLLSEEEAEAANELAANELIEQDAVPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3N3</accession>
    <name>A0A2S9H3N3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative metal-dependent hydrolase with the TIM-barrel fold</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0574</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94571">
        <property type="protein sequence ID" value="PRC94571"/>
        <property type="gene ID" value="S2091_0574"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01300">
        <property type="entry name" value="YtcJ_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013108">
        <property type="entry name" value="Amidohydro_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033932">
        <property type="entry name" value="YtcJ-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07969">
        <property type="entry name" value="Amidohydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="SSF51338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015605194" evidence="1">
        <location>
            <begin position="23"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="domain" description="Amidohydro_3" evidence="2">
        <location>
            <begin position="76"/>
            <end position="581"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="592" mass="63853" checksum="79BCE36901420B1D" modified="2018-07-18" version="1">MRLKMNLVIGMCAMSLSGYVAATTPPEPASMVFTSGNVLTMDAKRTVAEAVAIRGNKIVAIGSDQEVKSYIGTGTKVIHLNGKTLLPGFIDAHIHPVDGAIRLGKCSADDVAQPVAQIVAKVLKECMGKEAGASAAANKWIEVVNVNPSNFIATTADLDKISRTRPVIFEGTDGHTSWVNSVALKLAKITADTPNPAGGQIERDAKGQATGFLKDEAQGSVMAVMPKMALAQRIKLSQQAFALIRSKGITSVQDAWTSPDEMEVYEALEKSQQLNLRVRATLKSTIADDEAEYQRLAAIRSHFVGHPLIRADAVKIFSDGVIEYPTQTAAMIEPYLDGKGVPTTNYGGRYFAQDTLNKYVARLDKDGFTVHVHSIGDFTTHAALDAFQYARDKNGVNDNRHQITHLQIVDPADYPRFAKLNVYADMQLYWADPEEYSVGAVQPYISAERFDHMYPAGSLKKAGAVIVGCSDWPVDAAPGDPMPNTPLSAMQMAITRQNSNSSSSYFGKVLNADERVDIDTMLAAYTINAAKAMQQDNTTGSIEVGKLADLVVLGQNPMTIAPEKLSAIPVQYTIFDGAILYQLKPGAVATAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3Q9</accession>
    <name>A0A2S9H3Q9_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_0627</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94624">
        <property type="protein sequence ID" value="PRC94624"/>
        <property type="gene ID" value="S2091_0627"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Histidine kinase" evidence="3">
        <location>
            <begin position="238"/>
            <end position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC94624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="436" mass="48578" checksum="0A11143A92832976" modified="2018-07-18" version="1">MRRSLPLTSRCILIALVLQLAALALNYGLQCFFPAKVSLIATCLFILPLSALFIYQQTQPFLSLLRAINGTVASYKDGDYSFSLRWLKDDELGELVTAHNELGNVLREQRLHLVQKELLLDNMVQNTPVAMLLVCDHGPIVYANVAARKLLNYGQKLEGHAFEQILQQANQSLIEAVQRGGDGIFSVIETDSQEEDVYYLARRHFMLNGRSHELFLLRQLTNELRRQDVKTWKKVIRVISHELNNSLAPIASLANSGTELVRRNQVERLPVILETIAERCRHLENFIQGYASFSKLPTPRLESVTWPNLMNVLQGQTVFDLAGELPEKSARVDSAQLQQALLNLLKNAHESGCAGSEVSMSVQQIHDHFRIDVMDRGSGMSETVMTSALIPFYSTKRTGTGLGLALAREIVEAHGGRIVLANRAGGGLVVSLIFPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3U7</accession>
    <name>A0A2S9H3U7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative enzyme involved in biosynthesis of extracellular polysaccharide</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0606</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94603">
        <property type="protein sequence ID" value="PRC94603"/>
        <property type="gene ID" value="S2091_0606"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007138">
        <property type="entry name" value="ABM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03992">
        <property type="entry name" value="ABM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABM" evidence="1">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="100" mass="11609" checksum="E2442E04A62CBC16" modified="2018-07-18" version="1">MIIVIFRSRLNLELQAEYMEWAKRMSSLAEKIPGHISHKGFVAQDGERVTLVEFETEEAMKIWARHPEHVAAKKKGRNSFFSEYNVKICTLDRESAFPVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3Y7</accession>
    <name>A0A2S9H3Y7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0646</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94643">
        <property type="protein sequence ID" value="PRC94643"/>
        <property type="gene ID" value="S2091_0646"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="190" mass="22245" checksum="26494580BFF9F58B" modified="2018-07-18" version="1">MLKSGQADVGLHVSYTEERAHYVHWPKNWVWKADFVFMTNQKTKAAYPLHNYDDVRRSGLLIGIVYNNAYYPNFWEAFPSPDRAHQHYDAQLDPATDAATNLRKLEAGHIQLFPTPLVLGTYMIRSMKLANVTYYDWILFTKPYPNAFSDASTYSTTRYPNINALMQAYDLQLARLKSDQIKYQQFIQRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H401</accession>
    <name>A0A2S9H401_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">EamA-like transporter family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0717</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94714">
        <property type="protein sequence ID" value="PRC94714"/>
        <property type="gene ID" value="S2091_0717"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="92"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="120"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="147"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="178"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="214"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="248"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="273"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="10"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="149"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="308" mass="32786" checksum="3AFC46914823C575" modified="2018-07-18" version="1">MKPANIVRLLLLGGMWGMSFIFMRIASPAFGPILTAFGRVSFGGLVLIALLLLNNLSLDWRRNARFYLVIGLVNTAVPFSLFSWAALSIPSAYMAIINAMAPLFAALFGAVLLSESLSAVRIFGFVLGVIGVAILVGIGPAHVNFETLSGIAASVIAAICYGYAAIYIRQVAVKAPPLAVAAGSQIAASLFLFPIALIVTWVHPPSWPTTLYLTVRSVGAIVLLGVICTGIAYALYFRLIADEGASRAVTVAFLIPIAATIWASLFLNERITIGTLCGMGLVIIAIGLVLGLVRMPHRQWISKEQKNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H418</accession>
    <name>A0A2S9H418_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Malonate decarboxylase, gamma subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0725</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94722">
        <property type="protein sequence ID" value="PRC94722"/>
        <property type="gene ID" value="S2091_0725"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044262">
        <property type="term" value="P:cellular carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009648">
        <property type="entry name" value="Malonate_gamma"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03134">
        <property type="entry name" value="malonate_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="278" mass="29814" checksum="F9E53959C449A9AF" modified="2018-07-18" version="1">MNSKSEALSKRGATWFGHLAANANFHSGYPPSILVADADLDGQSARYIAVIPDPNNRFARARSGEVGLLEGWHIARAVDEIVKQDQISANKTPIVAIVDVVSQAYGRREEAYGIHVALAAAAGAYATARLAGHPVIALLVGKAMSGAFLAHGYQANRIIAINDPEVMVHAMGKESAAKITMRSVEALESLASTIPPMAYDIQSFASLGLLSKLVSLNNPDQPDTADIERVQESLRDALKSIVNDNNSDLSGRLTAPNRQATRTVRRLLQDQWGVHSNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H448</accession>
    <name>A0A2S9H448_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Glutamine--fructose-6-phosphate aminotransferase [isomerizing]</fullName>
            <ecNumber evidence="2 8">2.6.1.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">D-fructose-6-phosphate amidotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">GFAT</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Glucosamine-6-phosphate synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Hexosephosphate aminotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">L-glutamine--D-fructose-6-phosphate amidotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">glmS</name>
        <name evidence="11" type="ORF">S2091_0751</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>D-fructose 6-phosphate + L-glutamine = D-glucosamine 6-phosphate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:13237"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:58725"/>
            <dbReference type="ChEBI" id="CHEBI:61527"/>
            <dbReference type="EC" id="2.6.1.16"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.16" evidence="2 8"/>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94748">
        <property type="protein sequence ID" value="PRC94748"/>
        <property type="gene ID" value="S2091_0751"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097367">
        <property type="term" value="F:carbohydrate derivative binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004360">
        <property type="term" value="F:glutamine-fructose-6-phosphate transaminase (isomerizing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901137">
        <property type="term" value="P:carbohydrate derivative biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05008">
        <property type="entry name" value="SIS_GlmS_GlmD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05009">
        <property type="entry name" value="SIS_GlmS_GlmD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00164">
        <property type="entry name" value="GlmS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035466">
        <property type="entry name" value="GlmS/AgaS_SIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035490">
        <property type="entry name" value="GlmS/FrlB_SIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005855">
        <property type="entry name" value="GlmS_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001347">
        <property type="entry name" value="SIS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046348">
        <property type="entry name" value="SIS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10937:SF0">
        <property type="entry name" value="PTHR10937:SF0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01380">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53697">
        <property type="entry name" value="SSF53697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01135">
        <property type="entry name" value="glmS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51464">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 8" id="KW-0808">Transferase</keyword>
    <feature type="initiator methionine" description="Removed" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="9">
        <location>
            <begin position="2"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="domain" description="SIS" evidence="10">
        <location>
            <begin position="281"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="domain" description="SIS" evidence="10">
        <location>
            <begin position="454"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile; for GATase activity" evidence="8">
        <location>
            <position position="2"/>
        </location>
    </feature>
    <feature type="active site" description="For Fru-6P isomerization activity" evidence="8">
        <location>
            <position position="600"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC94748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="605" mass="66160" checksum="93A1934957001557" modified="2018-07-18" version="1">MCGIVGAVAQRNITPILLEGLKRLEYRGYDSCGIALHTHGELQRSRSTSRVAELEKQIEQSGLSGFTGIAHTRWATHGVPSTDNAHPHFSRQRIALVHNGIIENHEELRAELRALGYVFESQTDTEVIAHLVDHLYQGDLFETVQQAVKRLHGAYAIAVFCRDEPHRVIGARQGSPLIVGVGQGENFLASDAMAIAGTTDQIIYLEEGDVVDLQLQRCWIVDANGRPVQREVRTVHAHTGAAELGPYRHYMQKEIFEQPRAIGDTLDGVTGIMPELFGDAAHGVFKKIDSLLILACGTSYYAGLTAKYWIESIAKIPVQVEVASEYRYRDSVPNPNSLVVTISQSGETADTLAALKHARSLGMEHTLTICNVATSAMVRECKLAYITRAGVEVGVASTKAFTTQLAALFLLTLALAQSKGRITEAAENEHLKAMRHLPVAISAVLALEPQIIAWSEDFARYENALFLGRGMHYPIALEGALKLKEISYIHAEAYPAGELKHGPLALVTKEMPVVTVAPKDALLEKLKSNMQEVRARGGELYVFADADSNISSSEGVHVIRLPENYGQLSPILHTVALQLLAYHTALARGTDVDKPRNLAKSVTVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H487</accession>
    <name>A0A2S9H487_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0791</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94788">
        <property type="protein sequence ID" value="PRC94788"/>
        <property type="gene ID" value="S2091_0791"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025245">
        <property type="entry name" value="DUF4197"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13852">
        <property type="entry name" value="DUF4197"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015758752" evidence="1">
        <location>
            <begin position="20"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="226" mass="23839" checksum="AFBDB504A32B4A90" modified="2018-07-18" version="1">MKFRTSIAVAALVSSSVWAASLADLSNTEATSGLRAALEKGAESAVGKLGVENGFLSNEKVRISLPSSLDKAQSILRMTGQGPKMDELIVAMNHAAEAAVPMAKPLLMNAIKSMSVTDAKNILSGGDTSVTDFFRQKTSAQLAEQFQPVVKSVTDKSDLSAKYNSLMGPAAKYGVVPAQQATVESYVTERAVDGLFLMIGEEEKAIRQDPLGTGSKIIGQVFGLLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4A8</accession>
    <name>A0A2S9H4A8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0019</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94824">
        <property type="protein sequence ID" value="PRC94824"/>
        <property type="gene ID" value="S2091_0019"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="171" mass="20168" checksum="2CDC7869E88A1A03" modified="2018-07-18" version="1">MCVRCMFAACLIFSIADTGQIYKRRLIYANTLLSACAGLRQSKHSQINLTFAFFTLIQTAIRAVQIQNAILSVYCVQLIWTMHVKLMALLIAHHLWKRHIAFHRFDHAALMRLHFLFDHIYENQRLHEVGHHFPHIHQYELSQRRIHLEQYLVVEQKLNLPFLPNQLTLGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4G5</accession>
    <name>A0A2S9H4G5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0075</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94880">
        <property type="protein sequence ID" value="PRC94880"/>
        <property type="gene ID" value="S2091_0075"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="43" mass="5141" checksum="B3BFBBB0A955FF48" modified="2018-07-18" version="1">MIFNALYNVVMILPPSMAIPFVIRNYHRSPYYKLAFPLVIIQW</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4G7</accession>
    <name>A0A2S9H4G7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Aerobic-type carbon monoxide dehydrogenase small subunit CoxS/CutS-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0028</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94833">
        <property type="protein sequence ID" value="PRC94833"/>
        <property type="gene ID" value="S2091_0028"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00207">
        <property type="entry name" value="fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002888">
        <property type="entry name" value="2Fe-2S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036884">
        <property type="entry name" value="2Fe-2S-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006058">
        <property type="entry name" value="2Fe2S_fd_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00111">
        <property type="entry name" value="Fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01799">
        <property type="entry name" value="Fer2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47741">
        <property type="entry name" value="SSF47741"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="SSF54292"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00197">
        <property type="entry name" value="2FE2S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="152" mass="16065" checksum="F32459A8C890F225" modified="2018-07-18" version="1">MITLNINGKDTQLDLDPSTPILWALRDTLNMTGTKFGCGAALCGACTVHLDGDAIRSCITPISSVVGKKITTIEAMETDKIGKAVQDAWVKHDVPQCGYCQSGQVMSATALLSSNKKPTDADIDNAMSGNICRCGTYQRIRAAIKDASATLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4N1</accession>
    <name>A0A2S9H4N1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Mechanosensitive ion channel</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_0098</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94903">
        <property type="protein sequence ID" value="PRC94903"/>
        <property type="gene ID" value="S2091_0098"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006685">
        <property type="entry name" value="MscS_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023408">
        <property type="entry name" value="MscS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00924">
        <property type="entry name" value="MS_channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="SSF50182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="15"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="57"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="81"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC94903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="289" mass="32878" checksum="D0D532FFD8B5CF81" modified="2018-07-18" version="1">MSEIVRFFHEIDRSFLRDILMTLVLITALAIVRAMLRRAILQRDSLQPEIKRRWLGTTRNVLLGILMLGIIMIWGNEIESFAVSLVAVAAAFVLATREMLLCILGSVYRTSTDVCRIGDWVEINGIKGQIIDMNLFSTSLVESSRSCSDKNTVGRAITIPNSMFFSQPMYNETRLGNFVTQSVHIKLERDDNWELAEQILLDVGNKIISEYADKLAHNTHKMTHIYALEAPLQHAQVWLSLDDINHVALHLQLPAPLGKSARIEQRILREFLSKMPPTTNYRTYANKAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H507</accession>
    <name>A0A2S9H507_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Rubredoxin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_0267</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>Fe(3+)</name>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the rubredoxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95072">
        <property type="protein sequence ID" value="PRC95072"/>
        <property type="gene ID" value="S2091_0267"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00730">
        <property type="entry name" value="rubredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024934">
        <property type="entry name" value="Rubredoxin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024935">
        <property type="entry name" value="Rubredoxin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018527">
        <property type="entry name" value="Rubredoxin_Fe_BS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00301">
        <property type="entry name" value="Rubredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00163">
        <property type="entry name" value="RUBREDOXIN"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00202">
        <property type="entry name" value="RUBREDOXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50903">
        <property type="entry name" value="RUBREDOXIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0249">Electron transport</keyword>
    <keyword evidence="5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Rubredoxin-like" evidence="7">
        <location>
            <begin position="19"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC95072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="72" mass="8211" checksum="0D3CF0CA37898356" modified="2018-07-18" version="1">MSNNIGTDFSENSNQNDEFKTWMCLICGWMYDEAAGIPDDGILPGTRWKDVPMNWTCPECGARKEDFEMIAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H513</accession>
    <name>A0A2S9H513_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative addiction module antidote protein, CC2985 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0253</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95058">
        <property type="protein sequence ID" value="PRC95058"/>
        <property type="gene ID" value="S2091_0253"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.10.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022789">
        <property type="entry name" value="ParD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038296">
        <property type="entry name" value="ParD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010985">
        <property type="entry name" value="Ribbon_hlx_hlx"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36582">
        <property type="entry name" value="PTHR36582"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03693">
        <property type="entry name" value="ParD_antitoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47598">
        <property type="entry name" value="SSF47598"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02606">
        <property type="entry name" value="antidote_CC2985"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-1277">Toxin-antitoxin system</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC95058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="92" mass="10234" checksum="22522FA5B34F1830" modified="2018-07-18" version="1">MPTRNIVLTDHQARFVEQLVTSGSYQNASEVLREGLRLVERREVENNMKLLALREAARIGIADIEAGASCLFNSPSELEQHLAKLASEVLKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H563</accession>
    <name>A0A2S9H563_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0319</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95124">
        <property type="protein sequence ID" value="PRC95124"/>
        <property type="gene ID" value="S2091_0319"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021370">
        <property type="entry name" value="DUF2987"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11205">
        <property type="entry name" value="DUF2987"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015497612" evidence="1">
        <location>
            <begin position="23"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC95124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="226" mass="25613" checksum="665F5C53D8F04E4F" modified="2018-07-18" version="1">MMKKLLITALTLLIVTTLPAHAEEREWVSYKKLVEATYLDKFYRVEQSQRDHLRLLIQVMPENKFITPSTIVLTVAHSGGKERLPISAEGYMDIVPNAEWIKEDAKIYTSLPKTEKSGIAAIFASKTPEALQLNYAELMASVPQWNALIKEQAGVLRFMLPKFNAILLHFPKAAQQTIQVIAKDGTKTYMTDSKGELKLKLDEALQKENPKVMLSEKPSWVEVDEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H572</accession>
    <name>A0A2S9H572_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_0268</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine + ATP = 4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + ADP</text>
            <dbReference type="Rhea" id="RHEA:19893"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57841"/>
            <dbReference type="ChEBI" id="CHEBI:58354"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.7"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>4-amino-5-hydroxymethyl-2-methylpyrimidine + ATP = 4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23096"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16892"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58354"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.49"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Cofactor biosynthesis; thiamine diphosphate biosynthesis; 4-amino-2-methyl-5-diphosphomethylpyrimidine from 5-amino-1-(5-phospho-D-ribosyl)imidazole: step 3/3.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95073">
        <property type="protein sequence ID" value="PRC95073"/>
        <property type="gene ID" value="S2091_0268"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00060">
        <property type="reaction ID" value="UER00138"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008972">
        <property type="term" value="F:phosphomethylpyrimidine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009228">
        <property type="term" value="P:thiamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009229">
        <property type="term" value="P:thiamine diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01169">
        <property type="entry name" value="HMPP_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045029">
        <property type="entry name" value="HMP/HMP-P_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004399">
        <property type="entry name" value="HMP/HMP-P_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013749">
        <property type="entry name" value="PM/HMP-P_kinase-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20858">
        <property type="entry name" value="PTHR20858"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08543">
        <property type="entry name" value="Phos_pyr_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="SSF53613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Phos_pyr_kin" evidence="4">
        <location>
            <begin position="16"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000565"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC95073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="279" mass="29750" checksum="F40C6DC11DF37F78" modified="2018-07-18" version="1">MQNQLSPLVLSFGSSDPLGAIGIQADLGSFAAMGCHGLTVITAILIGDTTQICDIEPIDAEILIEQARTILEDVPVAAFKLGTIGSVENVSAIAEIVSDYPEVPLIFDPFSSAIPDQGQDSEDIYLAANELIIPQTTLLIASAVEISRLAETWREPSTEDTLALDVQRLIESGCEYVFVTGTASNPTEVANCLFDETGIIRHDSWPRLSGSFIGSGSTLSAAITALVANGLDIPDAVLEAQEFTNAALAHAQRFGMGKLVPDRYFWAREPGETQDLDQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5E4</accession>
    <name>A0A2S9H5E4_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Peptidoglycan D,D-transpeptidase FtsI</fullName>
            <ecNumber evidence="6">3.4.16.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Penicillin-binding protein 3</fullName>
            <shortName evidence="6">PBP-3</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ftsI</name>
        <name evidence="9" type="ORF">S2091_0405</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.</text>
    </comment>
    <comment type="pathway">
        <text evidence="6">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell inner membrane</location>
            <topology evidence="6">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the transpeptidase family. FtsI subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.16.4" evidence="6"/>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95210">
        <property type="protein sequence ID" value="PRC95210"/>
        <property type="gene ID" value="S2091_0405"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008658">
        <property type="term" value="F:penicillin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008955">
        <property type="term" value="F:peptidoglycan glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009002">
        <property type="term" value="F:serine-type D-Ala-D-Ala carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000917">
        <property type="term" value="P:division septum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043093">
        <property type="term" value="P:FtsZ-dependent cytokinesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02080">
        <property type="entry name" value="FtsI_transpept"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037532">
        <property type="entry name" value="FtsI_transpept"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005311">
        <property type="entry name" value="PBP_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036138">
        <property type="entry name" value="PBP_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001460">
        <property type="entry name" value="PCN-bd_Tpept"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03717">
        <property type="entry name" value="PBP_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00905">
        <property type="entry name" value="Transpeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56519">
        <property type="entry name" value="SSF56519"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="5 6" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1 6 9" id="KW-0132">Cell division</keyword>
    <keyword evidence="6" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0133">Cell shape</keyword>
    <keyword evidence="6" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="6" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0717">Septation</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="34"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="domain" description="PBP_dimer" evidence="8">
        <location>
            <begin position="75"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="domain" description="Transpeptidase" evidence="7">
        <location>
            <begin position="263"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-ester intermediate" evidence="6">
        <location>
            <position position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF03717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC95210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="586" mass="63849" checksum="199D6F18830D24E5" modified="2018-07-18" version="1">MTKGPNSRNANAKGVPFSMNPVLALKLSAWRSRLVMFALFIGFVALICRAFWLQAVSTDFLQKQGESRYARTLELPATRGKITDRNGLVLASSVPVKAIWAIPEDVLAEPKEKIQQLAVLLEMSEADLRKKLDSDRQFVYLKRQVEQATADKIVALNLSGIQTRKEYKRFYPEGEAMAHVVGFTNVEDAGQEGMELAEQASLAGKLGSRRVIKDRLGRIVEDLRAVNEPHDGKELVLSIDSKIQYLAYAQLKETIEKFKAKAGGVVVIDVQTGEILALANLPSYNPNQRSELTGAQLRNRVMTDAYEPGSVMKPFTVSLALETNRVTPETVFQTAGRMTIGTATIGDAHESAALTVAQIIEKSSNIGTAKIALEMPAQEMWEMFTKVGFGQAPKFNFPGTATGRLRNYKTWKPIEQATMSYGHGLTASTIQLAHAYTIFARDGELIPLSLQKVSQPPVGERIISAKTAQTMRMMLETVTGPGGSAIRARVPGYRVAGKTGTAYKVEHGQYVKKYIASFCGFAPVSNPRIIVAVMVDEPDPSIGHYGGTVAAPLFSSITANALRTLNVPPDTSVTSVLPDNGLGDIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5F7</accession>
    <name>A0A2S9H5F7_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribosomal RNA small subunit methyltransferase H</fullName>
            <ecNumber evidence="6">2.1.1.199</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">16S rRNA m(4)C1402 methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">rRNA (cytosine-N(4)-)-methyltransferase RsmH</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rsmH</name>
        <name evidence="7" type="ORF">S2091_0407</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>cytidine(1402) in 16S rRNA + S-adenosyl-L-methionine = H(+) + N(4)-methylcytidine(1402) in 16S rRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42928"/>
            <dbReference type="Rhea" id="RHEA-COMP:10286"/>
            <dbReference type="Rhea" id="RHEA-COMP:10287"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74506"/>
            <dbReference type="ChEBI" id="CHEBI:82748"/>
            <dbReference type="EC" id="2.1.1.199"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the methyltransferase superfamily. RsmH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.199" evidence="6"/>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95212">
        <property type="protein sequence ID" value="PRC95212"/>
        <property type="gene ID" value="S2091_0407"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071424">
        <property type="term" value="F:rRNA (cytosine-N4-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070475">
        <property type="term" value="P:rRNA base methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01007">
        <property type="entry name" value="16SrRNA_methyltr_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002903">
        <property type="entry name" value="RsmH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023397">
        <property type="entry name" value="SAM-dep_MeTrfase_MraW_recog"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11265">
        <property type="entry name" value="PTHR11265"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01795">
        <property type="entry name" value="Methyltransf_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004486">
        <property type="entry name" value="MraW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81799">
        <property type="entry name" value="SSF81799"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00006">
        <property type="entry name" value="TIGR00006"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 6 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="5 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 6 7" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="6">
        <location>
            <begin position="52"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="72"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="96"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="117"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="124"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC95212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="336" mass="36728" checksum="F93470C37B258DF4" modified="2018-07-18" version="1">MTTPSTTIQTGSSSSTENSEFAHSTVLLNEAIAALQPLKSDGIYIDGTFGRGGHSRLLLSQLAPGARLIAFDKDLQAIANANQITDPRFSIVHNSFATMQEELNARGVHKVDGVLLDLGISSPQVDDATRGFSFRADGPLDMRMDTTRGMSAATWLDTATEKNIEEVIRNYGEERFAFQIAKAITARRQLAPISSTRELAELVAGAVKTREKGKDPATRTFQAIRIFINKELEDLESGLTQAFELLATDGKLVAISFHSLEDRIVKQFMASKVLLKQPDRRLPIRSENLPQPQMKLLGRVKPSDDEVAANPRARSAIMRVALRLADPASESAGKAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5G1</accession>
    <name>A0A2S9H5G1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Oligopeptide transporter, OPT family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_0419</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95224">
        <property type="protein sequence ID" value="PRC95224"/>
        <property type="gene ID" value="S2091_0419"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035673">
        <property type="term" value="F:oligopeptide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004814">
        <property type="entry name" value="Oligopep_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004813">
        <property type="entry name" value="OPT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045035">
        <property type="entry name" value="YSL-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31645">
        <property type="entry name" value="PTHR31645"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03169">
        <property type="entry name" value="OPT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00728">
        <property type="entry name" value="OPT_sfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00733">
        <property type="entry name" value="TIGR00733"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="27"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="53"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="91"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="118"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="195"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="246"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="303"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="367"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="392"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="422"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="448"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="488"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="622"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="648"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="695"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="744"/>
            <end position="761"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC95224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="767" mass="80617" checksum="51253A49FB61D08B" modified="2018-07-18" version="1">MSNPSQSNAVKPYIPADAQLPEFSLRAVIMGVVLGMVFGASSLYLVLKVGLTVSASIPVAVIAITLFRLTKKLGGQDSSILENSITQTAGSAGESIAFGLGVTMPAILILGFDLEISRVMLVGVLGGLLGILMMIPMRRTMIVEQHKELKYPEGTACAEVLKAAATETSRVAAGLVKPGDAAANEAELKADNKRAFIIFGGFGIGLLYKCINVAFKGWKDTPNFIFGAPLKAGSLGAEVSPELLGVGYIIGPKIASVMAAGGVMSYLLLIPMIKFFGDALTVPVAPGLKLISAMGPDEIRSAYILYIGAGAVATGGLVSLARAMPTIWRSLTAGLSGLSIPGMNGNANGKAKNGQASEVLRTDQDIPMKWVLIGGLVIITAITLSTPLHMNLLGALLIIVFGFLFSTVSSRLTGEIGSSSNPISGITVATLLFTCLIFLLMGWTGNRYYVTALSVGAIVCIAASNAGTTSQDLKTGFLVGSTPRLQQYAILIGALSSALILGPILLQLNDSATVYVPAAEVAPGIVVDASTLTDTAKLQGPQAATDSNTYKVWRKSDEVGGPSGKYLVDNSGKLVYLVDPGINGTHTKRPDGSEVKKFDAPKAVLMSYIIKGILDRQLPWELVLFGVMIAVILEMSGISSLAFAVGVYLPLSSTLPIFVGGMVRWLVDRRSNKMTKNQHLTEDEKQAVGDRSPGVLLASGYIAGGALAGILIAITAGVMTNFDQKLTDWATLHNPFFEGANSDLLTMLPYAVIVLLLYWVGREKKEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5H7</accession>
    <name>A0A2S9H5H7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposase DDE domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0386</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95191">
        <property type="protein sequence ID" value="PRC95191"/>
        <property type="gene ID" value="S2091_0386"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002559">
        <property type="entry name" value="Transposase_11"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01609">
        <property type="entry name" value="DDE_Tnp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_Tnp_1" evidence="1">
        <location>
            <begin position="2"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC95191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="117" mass="13429" checksum="5476DD429DD44D11" modified="2018-07-18" version="1">MFLTNNTALPATTIAALYKSRWQVELFFKWIKQYLRIKYFLGNSENAVKTQIWCAISTYVLIAIIKKELQLNASPYTLLQILSVSVFEKTQISCAFQTDGYISETAPTANQLNLFDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GS70</accession>
    <name>A0A2S9GS70_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4718</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000052">
        <property type="protein sequence ID" value="PRC90574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90574">
        <property type="protein sequence ID" value="PRC90574"/>
        <property type="gene ID" value="S2091_4718"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC90574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="108" mass="12033" checksum="339910E145C56BA2" modified="2018-07-18" version="1">MPDFQHVSHAVTREITHYRLSVRNPIAVLAKSCSGAIPGAHDGAAIRSYPARHDVSATITIRIRQLVRCSRLPYTQHRSRTLGIRSSLRIRIPHTGDSLTLPVLPDLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSI4</accession>
    <name>A0A2S9GSI4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acetyltransferase including N-acetylase of ribosomal protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4627</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000039">
        <property type="protein sequence ID" value="PRC90677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90677">
        <property type="protein sequence ID" value="PRC90677"/>
        <property type="gene ID" value="S2091_4627"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="47"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="220" mass="25021" checksum="44BF18E4BE92AC6A" modified="2018-07-18" version="1">MPLNIAYEKFCLNVKISYSVTFKIALFIMTFNPVLLDIPESFDSERLFIRAARPGDGAAHFAALQESHDDLRAHLADLPWVKAEASLANSEIFCRENWCRFIRREDLRFFMFSKSDASFIGSIGLHRIDWAVPKFEIGYWCRVSAQGNGYVGEAVHAITNFVIQHLAARRIEIRADDLNVSSWKVAEKAGFKLEGILRSAARDSVSNQLKDMRIYAKVVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSY0</accession>
    <name>A0A2S9GSY0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative phosphohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4474</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000035">
        <property type="protein sequence ID" value="PRC90811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90811">
        <property type="protein sequence ID" value="PRC90811"/>
        <property type="gene ID" value="S2091_4474"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP_ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallophos" evidence="1">
        <location>
            <begin position="38"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="294" mass="32889" checksum="9CD5E5D727AC7579" modified="2018-07-18" version="1">MIDRRKFLALTAAGGGAVFLSGLYRQAGATASTDDDFYFVQLSDSHWGFSGPPNPDAANTLQKAVASVNALEVPPDFIVFTGDLTHTTDDPKERRRRMAEFKEIIAGINIKTIHFMPGEHDASLDNGAAFKEYFGATHYTFDHKGVHFIVLDNVSDPGARIGDEQLSWLKNDLDQQKPDARIVLFTHRPLFDLVPKWDWATRDGDKAIALLMPYSNVTVFYGHIHQEHHHQTGHINHHAAQSLIFPLPAPGSQEKRTPLPWNPAAPYQGIGFREVEAKKVEPQYQIVEFPVTKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTT7</accession>
    <name>A0A2S9GTT7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4148</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000028">
        <property type="protein sequence ID" value="PRC91147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91147">
        <property type="protein sequence ID" value="PRC91147"/>
        <property type="gene ID" value="S2091_4148"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010727">
        <property type="entry name" value="DUF1302"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06980">
        <property type="entry name" value="DUF1302"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015417307" evidence="1">
        <location>
            <begin position="46"/>
            <end position="639"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="639" mass="68411" checksum="D60CA28D31F1BC70" modified="2018-07-18" version="1">MIDLGKSGKQRQLLRLKPRVMAQACSVALMALSVGGISYSSTAFADAFTLDNGDQGQWTADMSLGNTWRTMNANPALYSKPYGGTAGDGNQDGNLNYGKGDSVSTPFTISGELQLKHDTFGVVLGLKAWYDYTLEHKTVPIGSAANGFIANSKLNDSNYAPLSKFSGVAVNNAYLFNTFSTFDDKPLTIKLGDQVVNWGESLFIPGMNQFGAFNLGATHEPGATVKDILIPIPQVSANWGLGGGLSVEAFYQFVWIPNVAPGCGTFFSPSDVYNCGNATTPLLGDAIGNQYTQLTGSPLLHGINFGVSSLPEKDPKSSGQAGISSHYFASSISTDFGVYFARYNQRTPDLSISNTPSNNPLSIYSGNYTGKLGAKAGVANFLSPLTAYWDYSATDIQVAGLSAATEVGGWSLAGEVSYTKGLPVQINPADLVVGEQLGKLFGPLAGPLYKMGSSPSNSEIQGYDLHNKSQLQMNTTKVLSQVIGAESLTLVGEVGMQHWSGIGDPNDPASIRYGRAFLYGFATNNAAVCAKLNPNPAYCAANGFDTSSAWGYRMQAELSYPNALAGWNLKPRVFWSQDVRGTSGDGIFLQDRETLGLVLRADYLNKYYAQIAYTTYNHHAIYDPMNDRDNISAVIGIHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTX6</accession>
    <name>A0A2S9GTX6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative metal-dependent hydrolase with the TIM-barrel fold</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4160</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000028">
        <property type="protein sequence ID" value="PRC91159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91159">
        <property type="protein sequence ID" value="PRC91159"/>
        <property type="gene ID" value="S2091_4160"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01300">
        <property type="entry name" value="YtcJ_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013108">
        <property type="entry name" value="Amidohydro_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033932">
        <property type="entry name" value="YtcJ-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07969">
        <property type="entry name" value="Amidohydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="SSF51338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydro_3" evidence="1">
        <location>
            <begin position="84"/>
            <end position="599"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="604" mass="64842" checksum="40CE26BB358D6305" modified="2018-07-18" version="1">MTLKPIFSSLTIGTIAVAVLTLTGCANSPNTKQALQADTVYRNGYIYTVDASDSVQQALAVRDGRIMYVGSNDGAEKLIANTTKVIDLKGRMLMPGLIDAHMHPMDGGDGLRGCNLNYEALTITQFQARIQACLDADAGNEPDGWLEVTNWYRQAMLPKGADAVRATLDVLRTKRPIQVQSSDYHSVLANSRAIQLAGINAASKNPEGGSIARDAAGIPTGIFEDEASSLIAAVKPPHPASDAIISANLALGVLRTQGVTTFFDALADEPQLTAFAALQNSGKLTARAYFAPLITTDMASKPADAVAMLQDLAKRFDQGSVNVNPTISVHHAKLFMDGVVQTPAFTAALLKPYFVNQGSETHPNFVPGTLSGQIYLPSDVLNPMMVALAKAGFNPHIHAIGDRAVREALDAVAEMRKQVPDPSIRPGIAHVEVTDPADYSRFAQLNVTPVMSFQWAKPAPDMTDATKDFLGPVRFARMEPEGSLHAAGARIAFGSDWPCDPFNEWFALKVGVTRTNNPALWGKYPGRLNADVGLSRKEVLRAATMNSAYTLHLEKDAGSLEVGKLADLIILDRNFFSIDEEQIANIKVQATIVGGKVVYQADGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GU35</accession>
    <name>A0A2S9GU35_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 3">Iron-sulfur cluster assembly scaffold protein IscU</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_4027</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the NifU family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000026">
        <property type="protein sequence ID" value="PRC91242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91242">
        <property type="protein sequence ID" value="PRC91242"/>
        <property type="gene ID" value="S2091_4027"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06664">
        <property type="entry name" value="IscU_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011339">
        <property type="entry name" value="ISC_FeS_clus_asmbl_IscU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002871">
        <property type="entry name" value="NIF_FeS_clus_asmbl_NifU_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10093">
        <property type="entry name" value="PTHR10093"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01592">
        <property type="entry name" value="NifU_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01999">
        <property type="entry name" value="iscU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NifU_N" evidence="4">
        <location>
            <begin position="2"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00014836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU362089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC91242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="128" mass="13594" checksum="61FF599BC9DB41D9" modified="2018-07-18" version="1">MAYSEKVLDHYENPRNVGAFDKGDESIGTGMVGAPACGDVMKLQIKVGPDGVIQDAKFKTYGCGSAIASSSLVTEWVKGKTLDQALSIKNTQIAEELALPPVKIHCSILAEDAIKAAVLDYKTKHATV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GU53</accession>
    <name>A0A2S9GU53_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Co-chaperone protein HscB homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">hscB</name>
        <name evidence="6" type="ORF">S2091_4025</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 4">Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Interacts with HscA and stimulates its ATPase activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the HscB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000026">
        <property type="protein sequence ID" value="PRC91240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91240">
        <property type="protein sequence ID" value="PRC91240"/>
        <property type="gene ID" value="S2091_4025"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001671">
        <property type="term" value="F:ATPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044571">
        <property type="term" value="P:[2Fe-2S] cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051259">
        <property type="term" value="P:protein complex oligomerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00682">
        <property type="entry name" value="HscB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004640">
        <property type="entry name" value="HscB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036386">
        <property type="entry name" value="HscB_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009073">
        <property type="entry name" value="HscB_oligo_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14021">
        <property type="entry name" value="PTHR14021"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07743">
        <property type="entry name" value="HSCB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="SSF46565"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47144">
        <property type="entry name" value="SSF47144"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00714">
        <property type="entry name" value="hscB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="5">
        <location>
            <begin position="3"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00025596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC91240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="166" mass="19181" checksum="B26F432983448A72" modified="2018-07-18" version="1">MQNHFDLFQLSPQFDVDMAQLDRAFRDVQAQVHPDKFVSASSAEQRVAMQWATRANEAYQTLKNPLKRASYLCELNGVGLQAESNTAMPMAFLMQQMEWREELDEARQNSAALLRLETHINQAHRQQITQIAEQLAQPDYHQAAQLIRQLMFLEKFSEDVANAQEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GU67</accession>
    <name>A0A2S9GU67_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein-L-isoaspartate O-methyltransferase</fullName>
            <ecNumber evidence="2">2.1.1.77</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">L-isoaspartyl protein carboxyl methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="2">Protein L-isoaspartyl methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="2">Protein-beta-aspartate methyltransferase</fullName>
            <shortName evidence="2">PIMT</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">pcm</name>
        <name evidence="4" type="ORF">S2091_4062</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>[protein]-L-isoaspartate + S-adenosyl-L-methionine = [protein]-L-isoaspartate alpha-methyl ester + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:12705"/>
            <dbReference type="Rhea" id="RHEA-COMP:12143"/>
            <dbReference type="Rhea" id="RHEA-COMP:12144"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:90596"/>
            <dbReference type="ChEBI" id="CHEBI:90598"/>
            <dbReference type="EC" id="2.1.1.77"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.77" evidence="2"/>
    <dbReference type="EMBL" id="PUGF01000026">
        <property type="protein sequence ID" value="PRC91277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91277">
        <property type="protein sequence ID" value="PRC91277"/>
        <property type="gene ID" value="S2091_4062"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004719">
        <property type="term" value="F:protein-L-isoaspartate (D-aspartate) O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030091">
        <property type="term" value="P:protein repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00090">
        <property type="entry name" value="PIMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000682">
        <property type="entry name" value="PCMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11579">
        <property type="entry name" value="PTHR11579"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00080">
        <property type="entry name" value="pimt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01279">
        <property type="entry name" value="PCMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="60"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="12"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="60"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC91277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="304" mass="33146" checksum="F06C96B53C17B845" modified="2018-07-18" version="1">MTAKNRKFPLPLSSLENKSSNRAQQSTSSLLSVATPQTATQNVRQHEVRNDEASIKNSLPHNVLQHATSTRGGGSAEVTAEHRNESHHKMVNVPIISDAPRRAMVARLVKQGVRDEVVLAAMGAVPRHQFIESGLSGQAYIDASLPIGHQQTISQPYIVARMIEIMRNGRVLSNVLEIGTGCGYQAAVLAQLSENVYSIERIKLLHELAKKNLRSLRIANLRLHYGDGMHGLPQVAPFDGIILAAAGMQIPTALLQQLAIGGRLIAPVGEKQQVLQLIERTGNADWTRSVLEECYFVPLCSGII</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUA0</accession>
    <name>A0A2S9GUA0_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_3978</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="PUGF01000025">
        <property type="protein sequence ID" value="PRC91307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91307">
        <property type="protein sequence ID" value="PRC91307"/>
        <property type="gene ID" value="S2091_3978"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00088">
        <property type="entry name" value="HPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.560">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004105">
        <property type="entry name" value="CheA-like_dim"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037006">
        <property type="entry name" value="CheA-like_homodim_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036061">
        <property type="entry name" value="CheW-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002545">
        <property type="entry name" value="CheW-lke_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036641">
        <property type="entry name" value="HPT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008207">
        <property type="entry name" value="Sig_transdc_His_kin_Hpt_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01584">
        <property type="entry name" value="CheW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02895">
        <property type="entry name" value="H-kinase_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01627">
        <property type="entry name" value="Hpt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00260">
        <property type="entry name" value="CheW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00073">
        <property type="entry name" value="HPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47226">
        <property type="entry name" value="SSF47226"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50341">
        <property type="entry name" value="SSF50341"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50894">
        <property type="entry name" value="HPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HPt" evidence="5">
        <location>
            <begin position="1"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="4">
        <location>
            <begin position="267"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="modified residue" description="Phosphohistidine" evidence="3">
        <location>
            <position position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC91307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="611" mass="64602" checksum="41A18D36FB67405B" modified="2018-07-18" version="1">MLKEFVVEALDLATNVEEHLLSLERNPDDMQTLNAVFRSFHTIKGGAGFMNLTAMVEACHLTENLFDALRTGKAPVTLIAIEAALEASGFVADQLKALHNGTAPDQLSLMPHALEVILTNAIEGKGPPAAIAAVPVPTPVTPVVQATQIDADGIDWDALYQAVVPAGTSAASTAASSAISPTAAAAAATIAAAQIPLHSAVPIAKVSSAEVKQNLAPPKEESIRIDAVKLDVLLEVAGESVQAANQAGVLLEKLAQFKFDDSATVLMTALTETLSRASRYSTELQRASLATRMQPVGRLFQKFPRLVRELAKDLEKDVDLSISGAETEVDRVVVDSLYDPLVHMLRNSLDHGIETREERALTKKPAKSVIALKAWQEASSVMIEVTDDGKGMDANRLRTIAISKGLIGENDARSHEEAYQLVFLPGFSTKEVASSVSGRGVGMDVVKTAVEKHRGDIRITSNLGTGTSFLIRLPIELSIVPTMLVRTSSASLALPMAVVQRVVELPEIYETVGGSAVLRDQGTPLPVRSLASILGYEPCTERVGIVIAADNPYILALESVDGTSDLVIKPLTCISTPGITGTARSAEGELVLVIGLGFLLQGCEALGAVTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUA5</accession>
    <name>A0A2S9GUA5_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ribosomal RNA large subunit methyltransferase J</fullName>
            <ecNumber evidence="1">2.1.1.266</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">23S rRNA (adenine(2030)-N6)-methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">23S rRNA m6A2030 methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rlmJ</name>
        <name evidence="2" type="ORF">S2091_3986</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Specifically methylates the adenine in position 2030 of 23S rRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>adenosine(2030) in 23S rRNA + S-adenosyl-L-methionine = H(+) + N(6)-methyladenosine(2030) in 23S rRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:43736"/>
            <dbReference type="Rhea" id="RHEA-COMP:10668"/>
            <dbReference type="Rhea" id="RHEA-COMP:10669"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74449"/>
            <dbReference type="EC" id="2.1.1.266"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the RlmJ family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.266" evidence="1"/>
    <dbReference type="EMBL" id="PUGF01000025">
        <property type="protein sequence ID" value="PRC91315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91315">
        <property type="protein sequence ID" value="PRC91315"/>
        <property type="gene ID" value="S2091_3986"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036307">
        <property type="term" value="F:23S rRNA (adenine(2030)-N(6))-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070475">
        <property type="term" value="P:rRNA base methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00934">
        <property type="entry name" value="23SrRNA_methyltr_J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007473">
        <property type="entry name" value="RlmJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37426">
        <property type="entry name" value="PTHR37426"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04378">
        <property type="entry name" value="RsmJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="1" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="1" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="1">
        <location>
            <begin position="156"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="177"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="19"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="42"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="100"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="118"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="177"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="site" description="Interaction with substrate rRNA" evidence="1">
        <location>
            <position position="4"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="307" mass="34733" checksum="15A526753981E2B4" modified="2018-07-18" version="1">MLSYRHAFHAGNHADVLKHFITIQLLNYMGQKDAPFTYIDTHAGAGLYALDTGYAAKNAEYENGIAKLWEKKDLPAALVEYVDLIKELNPSGKLRYYPGSPYCAEHVMRLEDRLRLFELHPSDIKILHENMRKRELHQAEQGQKARGKRVMVMAGDGFEGLKALLPPQQRRALVLIDPPYEDKRDYKRVKDTLADSLQRFSAGTYAVWYPVLQRQESREFARKLSQLPVDSWLSVTLSISQAMPDGFGLHSSGMFIINPPWTMEAMLKEVMPYLVKTLGNDSAAKFTLESGQGAAPIGRKPVRPKTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUB3</accession>
    <name>A0A2S9GUB3_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Homogentisate 1,2-dioxygenase</fullName>
            <shortName evidence="6">HGDO</shortName>
            <ecNumber evidence="6">1.13.11.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Homogentisate oxygenase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Homogentisic acid oxidase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Homogentisicase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">hmgA</name>
        <name evidence="7" type="ORF">S2091_3964</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Involved in the catabolism of homogentisate (2,5-dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>homogentisate + O2 = 4-maleylacetoacetate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15449"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16169"/>
            <dbReference type="ChEBI" id="CHEBI:17105"/>
            <dbReference type="EC" id="1.13.11.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="6">Amino-acid degradation; L-phenylalanine degradation; acetoacetate and fumarate from L-phenylalanine: step 4/6.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Hexamer; dimer of trimers.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the homogentisate dioxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.13.11.5" evidence="6"/>
    <dbReference type="EMBL" id="PUGF01000025">
        <property type="protein sequence ID" value="PRC91293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91293">
        <property type="protein sequence ID" value="PRC91293"/>
        <property type="gene ID" value="S2091_3964"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00139">
        <property type="reaction ID" value="UER00339"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004411">
        <property type="term" value="F:homogentisate 1,2-dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006559">
        <property type="term" value="P:L-phenylalanine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006572">
        <property type="term" value="P:tyrosine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00334">
        <property type="entry name" value="Homogentis_dioxygen"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005708">
        <property type="entry name" value="Homogentis_dOase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022950">
        <property type="entry name" value="Homogentis_dOase_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11056">
        <property type="entry name" value="PTHR11056"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04209">
        <property type="entry name" value="HgmA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01015">
        <property type="entry name" value="hmgA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5 6" id="KW-0585">Phenylalanine catabolism</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0828">Tyrosine catabolism</keyword>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="285"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="364"/>
        </location>
        <ligand>
            <name>homogentisate</name>
            <dbReference type="ChEBI" id="CHEBI:16169"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="383"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC91293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="431" mass="47700" checksum="F5E204C19F2DBE6B" modified="2018-07-18" version="1">MSLKYQTGFGNEFATEALPGALPQGQNSPQRVAYGLYAEQISGTAFTAPRSHNRRSWLYRMRPAAVHQEFKQMDNGLIVSDFTQVPATPNQLRWNPLPLPSEPTDFIAGLATMAGTGSPDAQSGCAIHLYVANQDMTKRFFYSADGEFLIVPQQGRLLIKTELGNLEVEPQEIAIIPRGIRFQVSLPDGLARGYVCENFGGALRLPDLGVIGSNGLANPRDFEVPVAAYEDKEGEFELIAKFSGNLWQANIGHSPLDVVAWHGNYAPCKYDLRRFNTIGSISYDHPDPSIFLVLQAQSDTPGVDTIDFVIFPPRWLAAENTFRPPWFHRNIAAEFMGLIHGAYDAKAEGFVPGGSSLHNCMSGHGPDEQTFEKASVSDTSKPHKIADTMAFMFETRTILRPTRFAMEAPQRQANYASCWQGLAKHFTPEKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUN1</accession>
    <name>A0A2S9GUN1_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Histidine kinase</fullName>
            <ecNumber evidence="3">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">S2091_3857</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="3"/>
    <dbReference type="EMBL" id="PUGF01000023">
        <property type="protein sequence ID" value="PRC91442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91442">
        <property type="protein sequence ID" value="PRC91442"/>
        <property type="gene ID" value="S2091_3857"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00088">
        <property type="entry name" value="HPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036641">
        <property type="entry name" value="HPT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013656">
        <property type="entry name" value="PAS_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008207">
        <property type="entry name" value="Sig_transdc_His_kin_Hpt_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001638">
        <property type="entry name" value="Solute-binding_3/MltF_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01627">
        <property type="entry name" value="Hpt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08448">
        <property type="entry name" value="PAS_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00497">
        <property type="entry name" value="SBP_bac_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00073">
        <property type="entry name" value="HPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00062">
        <property type="entry name" value="PBPb"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47226">
        <property type="entry name" value="SSF47226"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50894">
        <property type="entry name" value="HPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 8" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5016298877" description="Histidine kinase" evidence="9">
        <location>
            <begin position="25"/>
            <end position="1225"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="12">
        <location>
            <begin position="582"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="13">
        <location>
            <begin position="652"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="10">
        <location>
            <begin position="725"/>
            <end position="947"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="11">
        <location>
            <begin position="969"/>
            <end position="1088"/>
        </location>
    </feature>
    <feature type="domain" description="HPt" evidence="14">
        <location>
            <begin position="1117"/>
            <end position="1212"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="8">
        <location>
            <position position="1018"/>
        </location>
    </feature>
    <feature type="modified residue" description="Phosphohistidine" evidence="7">
        <location>
            <position position="1156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="PRC91442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="1225" mass="136999" checksum="ABD8501699200542" modified="2018-07-18" version="1">MNRIASNLKFFLFLLVLASHFSIADTLAVDRLTLPERTVITRSDVPLSADDWHWLRTKKVLKLGVASPDTPPFDFSIYNREYAGATADYSDVVSQLLGTKFDVLRYANRELALKALADGQIDLLGTSNQFDVFERPFVLSTPYINGQSVLVSRIGDKRRFSLDLEGLSIAVASDYVTTSELSRRYPKAIIKIYPSINCAMGAAAFAQTDLLIADLTTAHYLLNRNYSRYLKLYKVSDVKSDGYSFAFKKSDVRLKNIVNKALSVIKLEQKINIMKRWGGTNSILIDTDRWIMTRAEQRWLTEHPVVSIEVPDYQAPISYFDEKGKFRGLVADILSNIELQTGIVFDVKRNPDFSSMEPQLHDGNIDVLGQLSYTDERAKSFLFTRPFFKDQHVFVVRKNGLPITSFRQLDNKKIALTANTILIKYLHEKFPTITIIETKNHIDALGFVESGKADATVDLLAVAEYYLPNLFHDRLIISSTIDLDSEGIISQPAFAVKRSDVELHSILDKALQAIPPDELELLVSRWQPNAPAAPQQWSDYQRLIYQVLGGAALCLIIALLWNLRLKRHTRELHSAQLALADQLKFMENLTNGAPFPIYVRDRNGTLLLCNDYMLNDLGLKKEDVIGKVSAVGLTDTQEIEGLEADVDRVLEQGVTIQGIRKLYKGDNVFWVYLWLLAYHDLTGEIKGVICSYIDVTERQQLLENLEKAKEIADSASKAKTTFLATMSHEIRTPINAVVGMLELVLKKADDDVFDRAAVEVAYSSAQHLLELIGDILDVVKIEANNLRLAPERCNLREQVESVVRVFDGLARQKGLRLVLDLDTSVNRDVLMDPMRFKQILSNIVSNAIKFTQSGQVTIRLAGTQPDSEHLQVQLLIKDSGIGISDEDQLRLFQPFSQAENNTLHGRVGTGLGLVISRTLCELMGGSLRLNSMAGEGTEVHITFTVSTLEPVLTLAAEPLKEPSPNGKLTILVVDDYLPNRLLLSEQLNYLGHKVSSAEDGAIGLKLWQKEFFDVVITDCNMPVMSGYDLVRTIRAEELETQRAACVVFGFTANAQEEERERCIAAGMNDCFFKPISLEALAKKLQITPHNPILRASTRPENLARYDLGGMEKLVGSQPQLIQKLIIELINSNRKDLNLLRVYSDNADVANLSELAHKIKGGANMIRANDVIFRCEELELACKDPVAMDRVSTAVIAMEASILALEKELLPLTVNSENQDGSGSIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUR6</accession>
    <name>A0A2S9GUR6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3866</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000023">
        <property type="protein sequence ID" value="PRC91451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91451">
        <property type="protein sequence ID" value="PRC91451"/>
        <property type="gene ID" value="S2091_3866"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010406">
        <property type="entry name" value="DUF1003"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06210">
        <property type="entry name" value="DUF1003"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="81"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="184" mass="20727" checksum="3C9B0A85894261C0" modified="2018-07-18" version="1">MNEPESSLDPITQNTKTILELSQFEEKSITRHQRILEYVSGVIGRPFFLGLTLLFVSFWIAANLLAHRMGFNVFDPPPFPLLQGLVGVGALLTTIIVLIKQNRLSKMEDRRAHLELQVNLLTEQKATKLISLMEELRRDLPMIKDRYDAESIALQVPTNPNSVLAALDGRKEKGGKHVKPDSVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GV75</accession>
    <name>A0A2S9GV75_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3730</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000021">
        <property type="protein sequence ID" value="PRC91614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91614">
        <property type="protein sequence ID" value="PRC91614"/>
        <property type="gene ID" value="S2091_3730"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009978">
        <property type="entry name" value="Na_H_antiport_3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07399">
        <property type="entry name" value="Na_H_antiport_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="84"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="127"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="163"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="206"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="247"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="270"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="299"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="331"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="363"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="402"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="422" mass="46063" checksum="CCF0F183F0ED3429" modified="2018-07-18" version="1">MQITPFIQYTAAVLFALAVLHTFCTKYFQHLAHTDSKHAGLWHLLGEVEVVFGFWSCILLLFITFSSSSKQAIAYLEDQNFTEALFVFVILTIAATSPILSFVSSLVNRITSILPVPAMLGRYFLCLSFIPILGSFITEPAAMTLSALLLRDLYFSKAVSNRFKYLTLAVLLVNISIGGVLTPYAAPPVLMVAEKWGWDLHFMSTVFGWKAAIAVFINASLVSLFFRKELAQLTANSTEQKVETKKMPAFLIIIHLLFLFGTVWFSHHPVAFIGLFLFFLGFTHAYPEHQEKLMLKEGLLVGFFLGGLVVLGSLQQWWLQPLISQMSSGTLFFGAIGLTALTDNAALTYLGSLVDGISDTAKYALVAGAVTGGGLTVIANAPNPAGFSILKECFDEQSISPLNVFLAALVPTAIAAACFGLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GV85</accession>
    <name>A0A2S9GV85_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putative threonine efflux protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_3740</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000021">
        <property type="protein sequence ID" value="PRC91624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91624">
        <property type="protein sequence ID" value="PRC91624"/>
        <property type="gene ID" value="S2091_3740"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001123">
        <property type="entry name" value="LeuE-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30086">
        <property type="entry name" value="PTHR30086"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01810">
        <property type="entry name" value="LysE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006324">
        <property type="entry name" value="LeuE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="88"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="121"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="162"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC91624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="184" mass="19844" checksum="1F233EA85B35A84E" modified="2018-07-18" version="1">MAFVMAHGVSYGLRGGAAASFGIGVADLVLTALTATGITAMVAAWPPAFDLIRYAGAVYLLWMAYKALQHPRGSVESVAAQTSLQSIFVRSMINSLLNPKALLFFMVFLPQFVDQSKGSVALQLIVLGCVLTVISTVFHTLLGTFGSSIRLFLSRHSYAARLQPYGLATVLLLLAFRLAFMRRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GV92</accession>
    <name>A0A2S9GV92_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Single-stranded-DNA-specific exonuclease RecJ</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_3571</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RecJ family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000020">
        <property type="protein sequence ID" value="PRC91633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91633">
        <property type="protein sequence ID" value="PRC91633"/>
        <property type="gene ID" value="S2091_3571"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008409">
        <property type="term" value="F:5'-3' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001667">
        <property type="entry name" value="DDH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038763">
        <property type="entry name" value="DHH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003156">
        <property type="entry name" value="DHHA1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004610">
        <property type="entry name" value="RecJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041122">
        <property type="entry name" value="RecJ_OB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01368">
        <property type="entry name" value="DHH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02272">
        <property type="entry name" value="DHHA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17768">
        <property type="entry name" value="RecJ_OB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64182">
        <property type="entry name" value="SSF64182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00644">
        <property type="entry name" value="recJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DHH" evidence="6">
        <location>
            <begin position="83"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="domain" description="DHHA1" evidence="7">
        <location>
            <begin position="330"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="domain" description="RecJ_OB" evidence="8">
        <location>
            <begin position="473"/>
            <end position="568"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00019841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF17768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC91633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="575" mass="62897" checksum="E1608BAE14DD73A4" modified="2018-07-18" version="1">MNTSDSTTKPSQIRTRPYPFRTSELLRQQGVHPVLARLFTARGVTSTSELSSELKALHAPTGLLHIEAAAIFLADSIAAQKKFVIVADYDCDGATACAVALRGLRMLGAQVDYIVPNRFEYGYGLTPEIVELTQRTTAPDIIITVDNGIASIEGVAEANRRGIEVLVTDHHLPAATLPDARVIVNPNQPDCGFPSKNLAGVGVMFYVLLALRAELRQRGQFDAATQPKLDVLLDLVALGTVADVVKLDANNRILVAQGLKRMRAGKMHAGIAALFRVAARNPQTATPFDLGFAVGPRLNAAGRMDDMKIGIECLTTDDEGRAWEIAQQLNTLNIERREKEAEMQDAALLILDDFQPQDSTTLCVFDESWHQGVIGIVASRLKDKFYRPTITFAPGGNGIIKGSGRSIPGFHLRDALDLVSKHAPDLIQKFGGHAMAAGLTIAAGDLPAFQAAFEAVGKHLLEPAQLERIIETDGVLEDAYYSVDFIHLLEQQVWGQGFPAPTFCDEFRLISQRVLKERHLKLMLEKNGQRYDAIWFGHTDNLPAKVKVAFRLDANEYNGVTRVQLLVEHVEGAVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVG7</accession>
    <name>A0A2S9GVG7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">NADH-dependent formate dehydrogenase delta subunit FdsD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3594</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000020">
        <property type="protein sequence ID" value="PRC91656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91656">
        <property type="protein sequence ID" value="PRC91656"/>
        <property type="gene ID" value="S2091_3594"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021074">
        <property type="entry name" value="Formate_DH_dsu"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11390">
        <property type="entry name" value="FdsD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="73" mass="8674" checksum="6DC9F3D0967AE150" modified="2018-07-18" version="1">MNVENLVTMANQIGSFYETMPDRNQALKDISGHLKKYWEPRMRRALLEHIDVDEETQLSPIVMESIRTHRELF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVH0</accession>
    <name>A0A2S9GVH0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3477</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000019">
        <property type="protein sequence ID" value="PRC91722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91722">
        <property type="protein sequence ID" value="PRC91722"/>
        <property type="gene ID" value="S2091_3477"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="142" mass="15368" checksum="0C61BC31A471D574" modified="2018-07-18" version="1">MRLHVLLIAGICTCASAQETQKLDIGHAEISGVLKNGSRVQPGDDVPTVPGKTYAGLRPERRLDVSAITSGMDSSPLAGAIKLGYLDNIQLIMDARQTAEYKRLYGKHVVVDCNIDYIGRYYTPVFCGVVSIVLKPSETSSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVK2</accession>
    <name>A0A2S9GVK2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Acyl-CoA dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_3510</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000019">
        <property type="protein sequence ID" value="PRC91755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91755">
        <property type="protein sequence ID" value="PRC91755"/>
        <property type="gene ID" value="S2091_3510"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003995">
        <property type="term" value="F:acyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006089">
        <property type="entry name" value="Acyl-CoA_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="SSF47203"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="SSF56645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00072">
        <property type="entry name" value="ACYL_COA_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA_dh_N" evidence="7">
        <location>
            <begin position="14"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_M" evidence="6">
        <location>
            <begin position="129"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_1" evidence="5">
        <location>
            <begin position="234"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC91755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="389" mass="42089" checksum="4C9CBBB08BF3EC6A" modified="2018-07-18" version="1">MSDTSYLAWPFFEPRHQELAAQLDQWASATLSQQHHADVDQACRTLVKQLGDAGWLQHAIAGKEYGATSDQIDTRVICLIRETLARHNGLADFAFAMQGLGSGAISLFGSQSQRANYLPKVAKGHAIAAFALSEPEAGSDVAAMQCQATLVGEHYILDGEKTWISNGGIADFYVVFARTGEQPGARGISAFIVDADNPGLQVAERIQVIAPHPLAKLKFTNCRVHSSQRIGDAGQGFKVGMATLDVFRTSVAAAALGFARRALDEALQHVKQRQMFGKTLADFQLTQAKVAQMATGIDSSALLTYRAAWQRDQGQRVTREAAMAKMTATETAQQVIDAAVQLFGGLGVVSGVPVECLYREIRALRIYEGATEVQQLIIARELLSEVNKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVL2</accession>
    <name>A0A2S9GVL2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Gram-negative porin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_3522</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000019">
        <property type="protein sequence ID" value="PRC91767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91767">
        <property type="protein sequence ID" value="PRC91767"/>
        <property type="gene ID" value="S2091_3522"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046930">
        <property type="term" value="C:pore complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015288">
        <property type="term" value="F:porin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006811">
        <property type="term" value="P:ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00342">
        <property type="entry name" value="gram_neg_porins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033900">
        <property type="entry name" value="Gram_neg_porin_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023614">
        <property type="entry name" value="Porin_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002299">
        <property type="entry name" value="Porin_Neis"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13609">
        <property type="entry name" value="Porin_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00184">
        <property type="entry name" value="NEISSPPORIN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0406">Ion transport</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0626">Porin</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1134">Transmembrane beta strand</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015617820" evidence="5">
        <location>
            <begin position="20"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="domain" description="Porin_4" evidence="6">
        <location>
            <begin position="9"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF13609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC91767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="371" mass="39255" checksum="EBB0BB8DCC7CA08D" modified="2018-07-18" version="1">MKKSLFMLAALGAPEFAEAQSNVTIYGIADMSINHFSGSNGGLQENNSVTRLDSNAGNNFAGSRLGFKGREDLGGGLSADFKLEMGIQMDTGRSEQGGRLFGRAANIGLNTGYGSLHLGRQDTPAFDLLNSSDPMGVGLAGTTANIHIGNKSAFPVGQPGAAPQQGWIGIGAIRANNSIRYDTPNFNGFSASVLYGMGEVASSSNGNLGIVGLNYKSQAMTIGYVHIDDNSAGVVTAQTADFKQKSDALAFTYDFKIAKLYTLAATKKADSAGIEDKANYYLLGMNAPITSRDQIMLSWNRSAGRNSNANSADQFSIGYSHALSKRTILYTSFSKILNKGNASFGIDGYDGHDGANFDYSRLFNAGILHSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVS8</accession>
    <name>A0A2S9GVS8_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6">Flagellar basal-body rod protein FlgC</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_3385</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="5 6">The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Bacterial flagellum basal body</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the flagella basal body rod proteins family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000018">
        <property type="protein sequence ID" value="PRC91829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91829">
        <property type="protein sequence ID" value="PRC91829"/>
        <property type="gene ID" value="S2091_3385"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030694">
        <property type="term" value="C:bacterial-type flagellum basal body, rod"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071973">
        <property type="term" value="P:bacterial-type flagellum-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001444">
        <property type="entry name" value="Flag_bb_rod_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019776">
        <property type="entry name" value="Flagellar_basal_body_rod_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010930">
        <property type="entry name" value="Flg_bb/hook_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006299">
        <property type="entry name" value="FlgC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00460">
        <property type="entry name" value="Flg_bb_rod"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06429">
        <property type="entry name" value="Flg_bbr_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01395">
        <property type="entry name" value="FlgC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00588">
        <property type="entry name" value="FLAGELLA_BB_ROD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0975">Bacterial flagellum</keyword>
    <keyword evidence="9" id="KW-0966">Cell projection</keyword>
    <keyword evidence="9" id="KW-0969">Cilium</keyword>
    <keyword evidence="9" id="KW-0282">Flagellum</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flg_bb_rod" evidence="7">
        <location>
            <begin position="7"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="domain" description="Flg_bbr_C" evidence="8">
        <location>
            <begin position="72"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00025933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF06429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC91829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="134" mass="14227" checksum="F4245A698D9FAA9A" modified="2018-07-18" version="1">MSLFDVFNVAGSAMSAQSQRLNVVASNLANADSVTSSNGQPYRAKQVVFSAVPVSDDNATGVQVQQVVEDTGPPMLKYDPQHPLADANGYVATPNVNVVDEMVNMISASRSYQTNVDTMNAAKTMLMKALTIGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVW4</accession>
    <name>A0A2S9GVW4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Activator of Hsp90 ATPase 1-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3551</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AHA1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000019">
        <property type="protein sequence ID" value="PRC91796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91796">
        <property type="protein sequence ID" value="PRC91796"/>
        <property type="gene ID" value="S2091_3551"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013538">
        <property type="entry name" value="Activator_of_Hsp90_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08327">
        <property type="entry name" value="AHSA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="166" mass="19116" checksum="6D214AA9BD4D83B2" modified="2018-07-18" version="1">MKADVQFDFLVNKEKSTITIKREFAAKRQLVWDCYTKSELLDQWFAPKPLTTKTKFMDFSEGGHWHYAMVEPSGQEYWGRMDYQTIQPITNYTSLDGFCDNTGALNPAFPRSKWNVTFSDITTHTLVETVVSYSSPEALQQVIKMGLKEGLTSTLERLDELLLILN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GW19</accession>
    <name>A0A2S9GW19_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 4">Nucleoside diphosphate kinase</fullName>
            <shortName evidence="2">NDK</shortName>
            <shortName evidence="2">NDP kinase</shortName>
            <ecNumber evidence="2 4">2.7.4.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Nucleoside-2-P kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">ndk</name>
        <name evidence="6" type="ORF">S2091_3475</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 4">
            <text>a 2'-deoxyribonucleoside 5'-diphosphate + ATP = a 2'-deoxyribonucleoside 5'-triphosphate + ADP</text>
            <dbReference type="Rhea" id="RHEA:44640"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:73316"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.6"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>a ribonucleoside 5'-diphosphate + ATP = a ribonucleoside 5'-triphosphate + ADP</text>
            <dbReference type="Rhea" id="RHEA:18113"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57930"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the NDK family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.6" evidence="2 4"/>
    <dbReference type="EMBL" id="PUGF01000018">
        <property type="protein sequence ID" value="PRC91919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91919">
        <property type="protein sequence ID" value="PRC91919"/>
        <property type="gene ID" value="S2091_3475"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004550">
        <property type="term" value="F:nucleoside diphosphate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006241">
        <property type="term" value="P:CTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006183">
        <property type="term" value="P:GTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006165">
        <property type="term" value="P:nucleoside diphosphate phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006228">
        <property type="term" value="P:UTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.141">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00451">
        <property type="entry name" value="NDP_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034907">
        <property type="entry name" value="NDK-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036850">
        <property type="entry name" value="NDK-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001564">
        <property type="entry name" value="Nucleoside_diP_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023005">
        <property type="entry name" value="Nucleoside_diP_kinase_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00334">
        <property type="entry name" value="NDK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01243">
        <property type="entry name" value="NUCDPKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00562">
        <property type="entry name" value="NDK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54919">
        <property type="entry name" value="SSF54919"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00469">
        <property type="entry name" value="NDP_KINASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4 6" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0546">Nucleotide metabolism</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1 2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NDK" evidence="5">
        <location>
            <begin position="3"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="active site" description="Pros-phosphohistidine intermediate" evidence="2">
        <location>
            <position position="117"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="11"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="59"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="87"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="93"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="104"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="114"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC91919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="141" mass="15150" checksum="F9291A1E976635AA" modified="2018-07-18" version="1">MAIERTLSIIKPDAVAKNVIGQIYSRFETAGLKIVAARMVQLSRAEAEGFYAVHSARPFFNDLVTFMISGPVMVSALEGDNAVLAHRDLMGATDPKKAEKGTIRADFADSIDANAVHGSDAVEAAAIEIAYFFPALSVYSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GW23</accession>
    <name>A0A2S9GW23_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Histidine--tRNA ligase</fullName>
            <ecNumber evidence="9">6.1.1.21</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Histidyl-tRNA synthetase</fullName>
            <shortName evidence="9">HisRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">hisS</name>
        <name evidence="11" type="ORF">S2091_3470</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>ATP + L-histidine + tRNA(His) = AMP + diphosphate + H(+) + L-histidyl-tRNA(His)</text>
            <dbReference type="Rhea" id="RHEA:17313"/>
            <dbReference type="Rhea" id="RHEA-COMP:9665"/>
            <dbReference type="Rhea" id="RHEA-COMP:9689"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57595"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78527"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.21"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="3 9">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.21" evidence="9"/>
    <dbReference type="EMBL" id="PUGF01000018">
        <property type="protein sequence ID" value="PRC91914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91914">
        <property type="protein sequence ID" value="PRC91914"/>
        <property type="gene ID" value="S2091_3470"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004821">
        <property type="term" value="F:histidine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006427">
        <property type="term" value="P:histidyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00773">
        <property type="entry name" value="HisRS-like_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00859">
        <property type="entry name" value="HisRS_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00127">
        <property type="entry name" value="His_tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004154">
        <property type="entry name" value="Anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036621">
        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015807">
        <property type="entry name" value="His-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041715">
        <property type="entry name" value="HisRS-like_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004516">
        <property type="entry name" value="HisRS/HisZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033656">
        <property type="entry name" value="HisRS_anticodon"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43707">
        <property type="entry name" value="PTHR43707"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03129">
        <property type="entry name" value="HGTP_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13393">
        <property type="entry name" value="tRNA-synt_His"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001549">
        <property type="entry name" value="His-tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00442">
        <property type="entry name" value="hisS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 9 11" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="10">
        <location>
            <begin position="1"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC91914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="449" mass="50118" checksum="AE60E7E12188CB1F" modified="2018-07-18" version="1">MSENKKLEKIVGVKGMNDMLPADAPLWELFENTAQSVFKSYGFQQIRTPIVEQTALFARGLGAVTDVVEKEMYSFEDSMNGDKLTLRPENTAGVVRAVIEHNLTYEGPKRLWYTGPMFRHERPQRGRYRQFQQMGAEALGFTGPDIDAELIMMCQRLWDDLGLQDVRLELNSIGDAEERNKHRADLIIYLDQHKEIMDAEALRRMYANPLRILDTKNPAMQAMVNAAPKLLDYLGAESLAHFEGVQAILRHNSIPFTINNRLVRGLDYYNRTVFEWVTDELGAQGTICAGGRYDTLVTMFGGKPTPSCGFAMGIERILELMKSAGEAHQPSQCDVYLVHQGADAQMQSFVLAERLRDAGLDVVLHCASITGIGSFKSQMKRADASGASFAIIVGEDEVAQGVAIVKALRGDAEQNNQATVPFDTVVDYLVDQIAGNDHHDHENCNHTHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GW34</accession>
    <name>A0A2S9GW34_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protein HflK</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_3464</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">HflC and HflK could encode or regulate a protease.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">HflC and HflK may interact to form a multimeric complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the band 7/mec-2 family. HflK subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000018">
        <property type="protein sequence ID" value="PRC91908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91908">
        <property type="protein sequence ID" value="PRC91908"/>
        <property type="gene ID" value="S2091_3464"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03404">
        <property type="entry name" value="SPFH_HflK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001107">
        <property type="entry name" value="Band_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036013">
        <property type="entry name" value="Band_7/SPFH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010201">
        <property type="entry name" value="HflK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020980">
        <property type="entry name" value="Membrane_HflK_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43327:SF2">
        <property type="entry name" value="PTHR43327:SF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01145">
        <property type="entry name" value="Band_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12221">
        <property type="entry name" value="HflK_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00244">
        <property type="entry name" value="PHB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117892">
        <property type="entry name" value="SSF117892"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01933">
        <property type="entry name" value="hflK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="79"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="domain" description="PHB" evidence="7">
        <location>
            <begin position="94"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="381"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="400"/>
            <end position="414"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU364113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC91908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="414" mass="45778" checksum="7D0BE96B9859FA1E" modified="2018-07-18" version="1">MVVSLLKKMGAIFSLNDPKWGRGSGNENDGNKPNTPSNGPPDLEDLWRDFNQKLNTMFGGKGAGSGGGRSPDSNGAKMGAGLIVIILLLLWLISGSFVVQEGQTGVVMTFGKFSHETTSGFNWRLPYPIQSHEIVNVSQVRTAEVGYQSNAKNKQPKEALMLTDDENIIDIQFAVQYKLKSAPDWIFNNREQESTVKQVAETAIREVVGRNKMDFVLYGSREKVAFDVSQLIQEILDRYKSGVQVTNVTVQGVQPPEQVQAAFDDAVKAGQDRERQKNEGQAYANDVIPKARGAAARLQEESQAYQARVVANAEGNASRFKQVLTEYQKAPAVTRDRMYYETMQQIFTSTTKMMIDTKNGNNMIYLPLDKLIGQTLSPDAAAPKSVGIPPAQEVTNANDLLRARDNHSRDREGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GW48</accession>
    <name>A0A2S9GW48_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Cysteine--tRNA ligase</fullName>
            <ecNumber evidence="11">6.1.1.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Cysteinyl-tRNA synthetase</fullName>
            <shortName evidence="11">CysRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">cysS</name>
        <name evidence="13" type="ORF">S2091_3442</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>ATP + L-cysteine + tRNA(Cys) = AMP + diphosphate + L-cysteinyl-tRNA(Cys)</text>
            <dbReference type="Rhea" id="RHEA:17773"/>
            <dbReference type="Rhea" id="RHEA-COMP:9661"/>
            <dbReference type="Rhea" id="RHEA-COMP:9679"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78517"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="11">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 11">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.16" evidence="11"/>
    <dbReference type="EMBL" id="PUGF01000018">
        <property type="protein sequence ID" value="PRC91886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91886">
        <property type="protein sequence ID" value="PRC91886"/>
        <property type="gene ID" value="S2091_3442"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004817">
        <property type="term" value="F:cysteine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006423">
        <property type="term" value="P:cysteinyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00672">
        <property type="entry name" value="CysRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00041">
        <property type="entry name" value="Cys_tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015803">
        <property type="entry name" value="Cys-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015273">
        <property type="entry name" value="Cys-tRNA-synt_Ia_DALR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024909">
        <property type="entry name" value="Cys-tRNA/MSH_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032678">
        <property type="entry name" value="tRNA-synt_1_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10890">
        <property type="entry name" value="PTHR10890"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09190">
        <property type="entry name" value="DALR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01406">
        <property type="entry name" value="tRNA-synt_1e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00983">
        <property type="entry name" value="TRNASYNTHCYS"/>
    </dbReference>
    <dbReference type="SMART" id="SM00840">
        <property type="entry name" value="DALR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="SSF47323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00435">
        <property type="entry name" value="cysS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 11" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="8 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 11 13" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9 11" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 11" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="DALR_2" evidence="12">
        <location>
            <begin position="347"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'HIGH' region" evidence="11">
        <location>
            <begin position="32"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'KMSKS' region" evidence="11">
        <location>
            <begin position="271"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="30"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="214"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="239"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="243"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="274"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PRC91886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="461" mass="51860" checksum="6DFFD7BD19237337" modified="2018-07-18" version="1">MNAQKIYNTLAREKQTFTPIEPGKVRMYVCGMTVYDYCHIGHARVMVVFDMVQRWLRASGYEVTYVQNITDIDDKIITRAVKNGESISALTGRYIQYMREDAAALGVLAPDHVPLATGYIPQMLGLIEKLQKNGLAYQGTDGDVNFSVRDFPGYGKLSGKSLDDLRAGERVDVNSGKRDPLDFVLWKSAKESEPEEVKWDSPWGRGRPGWHIECSAMAGDILGEQFDIHGGGQDLQFPHHENEIAQSEGAHQHQFVNYWMHNGFVRVDNEKMSKSLGNFFTIREVLKEYDPEVVRFFILRAQYRSQINYSDANLDDAKASLKRLYSTLKEVPADPLPLDLSEAFAQQFYSAMYDDFNSSLAVAALFELATEVNKTKSAALARQLKLLAGIIGFLQREPQEFLHAGNENGMAESEIAAKIADRTAAKLAKNFAESDRLRAELLANNIILEDKPGGITEWRRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GW60</accession>
    <name>A0A2S9GW60_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3292</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000017">
        <property type="protein sequence ID" value="PRC91950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91950">
        <property type="protein sequence ID" value="PRC91950"/>
        <property type="gene ID" value="S2091_3292"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="67" mass="7365" checksum="70DB5D0752AF6E82" modified="2018-07-18" version="1">MTPGQVQQAKLIKESFRECGLTFTQRGKENDASKRFTACAGSIKCIMVKHDIAVRPGMKTPGDQPPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWC8</accession>
    <name>A0A2S9GWC8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Outer membrane lipoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3170</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000016">
        <property type="protein sequence ID" value="PRC92035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92035">
        <property type="protein sequence ID" value="PRC92035"/>
        <property type="gene ID" value="S2091_3170"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015733928" evidence="1">
        <location>
            <begin position="27"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="152" mass="15405" checksum="C1FF8D95C0C1FDAB" modified="2018-07-18" version="1">MKKVLLLISVLSIAALTGCAVTPNSANVYQSRQTMGEQSVRMGVVESIRNVMIDHGQSGVGTLGGAALGGIAAGSSIGQGNGAVAAGIAGAIVGGLVGQHVEQNMNTKPGLEITVKLDNGNLTAIVQDADEQFNVGDRVRLLSGGRTTRVTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWD6</accession>
    <name>A0A2S9GWD6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Spermine/spermidine synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3168</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000016">
        <property type="protein sequence ID" value="PRC92033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92033">
        <property type="protein sequence ID" value="PRC92033"/>
        <property type="gene ID" value="S2091_3168"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="267" mass="30164" checksum="56EF332195360FB0" modified="2018-07-18" version="1">MLIKRKSIEAQANTKSGVNNSPKRKVKYAPVTLSEMDGCRYLHFGTEWVQGAMRLRKPDWLELEYAQQMMAWMLFIEKPQQIAQLGLGTASLTKFCYRQFPHAQVTAIELNPSVISICQTMFKLPDNDARLQVLEMDGEEFVNETSRYGTLDVLQVDVYDATARGPVLDSAEFYQACSDCLKPDGIMTVNLFGDHPSYLKNIKAMKFVFDQVICLPEVHDGNVIAIAFNTKVKFDFAALHERAAQIKLSTKLPAKSWVNGIQLAMQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWH1</accession>
    <name>A0A2S9GWH1_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">50S ribosomal protein L33</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpmG</name>
        <name evidence="7" type="ORF">S2091_3210</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the bacterial ribosomal protein bL33 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000016">
        <property type="protein sequence ID" value="PRC92075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92075">
        <property type="protein sequence ID" value="PRC92075"/>
        <property type="gene ID" value="S2091_3210"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00294">
        <property type="entry name" value="Ribosomal_L33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038584">
        <property type="entry name" value="L33_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001705">
        <property type="entry name" value="Ribosomal_L33"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018264">
        <property type="entry name" value="Ribosomal_L33_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011332">
        <property type="entry name" value="Ribosomal_zn-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00471">
        <property type="entry name" value="Ribosomal_L33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57829">
        <property type="entry name" value="SSF57829"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01023">
        <property type="entry name" value="rpmG_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00582">
        <property type="entry name" value="RIBOSOMAL_L33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC92075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="55" mass="6403" checksum="71EB14FCD3AF8E61" modified="2018-07-18" version="1">MAKSGRDKIKLESTAGTGHFYTTSKNKRSMPEKMEIMKFDPKARKHVIYKETKIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWN9</accession>
    <name>A0A2S9GWN9_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Bifunctional protein FolD</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="10">Methylenetetrahydrofolate dehydrogenase</fullName>
                <ecNumber evidence="10">1.5.1.5</ecNumber>
            </recommendedName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="10">Methenyltetrahydrofolate cyclohydrolase</fullName>
                <ecNumber evidence="10">3.5.4.9</ecNumber>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name evidence="10" type="primary">folD</name>
        <name evidence="13" type="ORF">S2091_3253</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + NADP(+) = 5,10-methenyltetrahydrofolate + NADPH</text>
            <dbReference type="Rhea" id="RHEA:22812"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:57455"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.5.1.5"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>5,10-methenyltetrahydrofolate + H2O = (6S)-10-formyltetrahydrofolate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57454"/>
            <dbReference type="ChEBI" id="CHEBI:57455"/>
            <dbReference type="EC" id="3.5.4.9"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="10">One-carbon metabolism; tetrahydrofolate interconversion.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.5.1.5" evidence="10"/>
    <dbReference type="EC" id="3.5.4.9" evidence="10"/>
    <dbReference type="EMBL" id="PUGF01000016">
        <property type="protein sequence ID" value="PRC92118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92118">
        <property type="protein sequence ID" value="PRC92118"/>
        <property type="gene ID" value="S2091_3253"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00193"/>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004477">
        <property type="term" value="F:methenyltetrahydrofolate cyclohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004488">
        <property type="term" value="F:methylenetetrahydrofolate dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009086">
        <property type="term" value="P:methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006164">
        <property type="term" value="P:purine nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035999">
        <property type="term" value="P:tetrahydrofolate interconversion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01080">
        <property type="entry name" value="NAD_bind_m-THF_DH_Cyclohyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01576">
        <property type="entry name" value="THF_DHG_CYH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminiacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000672">
        <property type="entry name" value="THF_DH/CycHdrlase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020630">
        <property type="entry name" value="THF_DH/CycHdrlase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020867">
        <property type="entry name" value="THF_DH/CycHdrlase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020631">
        <property type="entry name" value="THF_DH/CycHdrlase_NAD-bd_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00763">
        <property type="entry name" value="THF_DHG_CYH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02882">
        <property type="entry name" value="THF_DHG_CYH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00085">
        <property type="entry name" value="THFDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="SSF53223"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00767">
        <property type="entry name" value="THF_DHG_CYH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 10" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7 10" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="4 10 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 10" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="9 10" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="5 10" id="KW-0521">NADP</keyword>
    <keyword evidence="1 10" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="6 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3 10" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="THF_DHG_CYH" evidence="11">
        <location>
            <begin position="6"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="THF_DHG_CYH_C" evidence="12">
        <location>
            <begin position="124"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="165"/>
            <end position="167"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="190"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PRC92118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="282" mass="29760" checksum="AF0A0C1350258557" modified="2018-07-18" version="1">MTAQLIDGVQLSKHIRAEVTQRAAALTSAGKQPGLVVILVGENPASQVYVRNKVKACEDCGIYSVLEKHPAELSEAALLERISALNADPKINGILVQLPLPAHIDTHKVLEAIALEKDVDGFHIHNAGLLMTGQPLFRPCTPYGVMKMLEAISYPVRGAHAVIVGASNIVGKPQAMLLLQAGATVTICNSKTRDLGLHTRMADILVVATGKRNLVTAEMVKPGAVVIDVGMNRDDAGKLCGDVDFAGAKEVAGYITPVPGGVGPMTITMLLVNTIEAAERTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GX41</accession>
    <name>A0A2S9GX41_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Gamma-aminobutyrate permease and related permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_2930</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92271">
        <property type="protein sequence ID" value="PRC92271"/>
        <property type="gene ID" value="S2091_2930"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004841">
        <property type="entry name" value="AA-permease/SLC12A_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004840">
        <property type="entry name" value="Amoino_acid_permease_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00324">
        <property type="entry name" value="AA_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00218">
        <property type="entry name" value="AMINO_ACID_PERMEASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="25"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="50"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="103"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="131"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="161"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="203"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="246"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="288"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="337"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="363"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="407"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="434"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="domain" description="AA_permease" evidence="7">
        <location>
            <begin position="22"/>
            <end position="452"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC92271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="470" mass="51323" checksum="AFCF05CE20879748" modified="2018-07-18" version="1">MSNSTNTSTNTGGLKRELGERHIRMMALGACIGVGLFLGSARAIQMAGPAIMLSYILGGMAILVIMRALGEMAVHTPVAGSFSRYAQDYLGPLAGYLTGWNYWFLWIVTCVAETTAVAIYMGYWFPDMPRWIWALAALASMGSINLIAVKAFGEFEFWFALIKIVTIIAMIFGGIGVIAFGLGNDGVALGISNLWTHGGFMPNGWLGVLMSLPMVIFAYLGVEMIGLTAGEAKNPEKTIPQATNSVFWRILIFYVGALFVILSIYPWNQIGTQGSPFVMTFERLGIKTAAGIINFVVITAALSSCNGGIFSAGRMLFSLAQNGHAPAKFANISKNGVPHIALISTIVILLFGVLLNYLMPEKIFTIVTSIATFSGIWTWTMILLAQIKFRRSLSAEQCAGLKYRMKLWPISSYITLAFLVFVTVMMGYFEDTRVALIVGPVFLILLTIIYNIFKLSPEHRDNAPSIELAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXA2</accession>
    <name>A0A2S9GXA2_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">JmjC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2997</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92338">
        <property type="protein sequence ID" value="PRC92338"/>
        <property type="gene ID" value="S2091_2997"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003347">
        <property type="entry name" value="JmjC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039994">
        <property type="entry name" value="JmjC_protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13096">
        <property type="entry name" value="PTHR13096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08007">
        <property type="entry name" value="Cupin_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00558">
        <property type="entry name" value="JmjC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51184">
        <property type="entry name" value="JMJC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="JmjC" evidence="2">
        <location>
            <begin position="95"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="377" mass="42586" checksum="4B1E7F872A15454B" modified="2018-07-18" version="1">MKKLTLLGNITPTEFLRDYWHKKPLLIRQAIPNFKAPIEAAELIGLAAQEEVESRLVSHFKQQWKMENGPFTALPDIKKKEWSLLVQGVNLHHQAADALLRQFNFLPDARLDDLMISYASEGGGVGPHFDSYDVFLLQAHGQRRWKISAQKNLDLIDGMPLKILSNFTPEQEFVLEPGDMLYLPPQYAHDGIALGPCMTYSIGFRAPAYQELGEAFLQFMSDSIDLPGRYADPDLKPGKHPAELSKEMLEKVAQEIRKVEFTSEDITVFMGEYLSTPKHSVFFDQPKKPLTPVRFLIAAKQRGIQLALKSRMLYRGKNIFMNGESFGVSGVDKTLLTQLADTRSLDGALLATASIDMQETLCLWYEDGWINLQSPGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXE3</accession>
    <name>A0A2S9GXE3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3039</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92380">
        <property type="protein sequence ID" value="PRC92380"/>
        <property type="gene ID" value="S2091_3039"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="149" mass="15704" checksum="A9D84269E9D5FE37" modified="2018-07-18" version="1">MGGNPISSIDPFGLASINLGSGWTGRVDPVPGTEIWEIHVFDPQGNEAGLYNQQGWFNKHGKKGAPAGIPEQCENRLRGEAIDQMRRRGHIPGKGLGDIKGGNWKKFARILGPLGLVITIGIGISEGDSSGTITGDVICGELWGCGDAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXK7</accession>
    <name>A0A2S9GXK7_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein-L-isoaspartate O-methyltransferase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">L-isoaspartyl protein carboxyl methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Protein L-isoaspartyl methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Protein-beta-aspartate methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_2816</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92441">
        <property type="protein sequence ID" value="PRC92441"/>
        <property type="gene ID" value="S2091_2816"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004719">
        <property type="term" value="F:protein-L-isoaspartate (D-aspartate) O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000682">
        <property type="entry name" value="PCMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11579">
        <property type="entry name" value="PTHR11579"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00030757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00031323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00031350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC92441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="217" mass="23910" checksum="DED4539E10776BB6" modified="2018-07-18" version="1">MKLEQARFNMIEQQIRPWNVLDMGVLELLTIVKREKFLPTNQKSLAFMDTELPLPDGSLMLSPKMEARIVQEVAVKKHESALIVGAGSGYLPALLAFHARHVTCVETSPEVHLVAEQNLHHEGVANVSLELGDAAKGWPKAAPYDVIVMTGSLQVLPEELKQQLKVGGRLFVILGSAPIMTAFIYTRSSETEFVAKPLFETSIAAVPHAEHPSTFSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXL0</accession>
    <name>A0A2S9GXL0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2829</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92454">
        <property type="protein sequence ID" value="PRC92454"/>
        <property type="gene ID" value="S2091_2829"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="87" mass="9431" checksum="4B906F2A006DACEB" modified="2018-07-18" version="1">MAYAFEITCIATLPNARLAVFDGKLMQGCITTNSIADLVHGSEHFPLHVKGVILELAKNQCNILSLTFELDQKALAIAAVGDWLICD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXS8</accession>
    <name>A0A2S9GXS8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative O-methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_2894</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92519">
        <property type="protein sequence ID" value="PRC92519"/>
        <property type="gene ID" value="S2091_2894"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008171">
        <property type="term" value="F:O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002935">
        <property type="entry name" value="SAM_O-MeTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01596">
        <property type="entry name" value="Methyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51682">
        <property type="entry name" value="SAM_OMT_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC92519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="195" mass="21596" checksum="C952DFEA299AFB6A" modified="2018-07-18" version="1">MNSTLKNLLEELEAFGHTNDDSVKDRPRRMLNITHDTGEFLSVLIRIMGAKRVLEIGTSNGYSTLWLADALRTIDGTVKTVEMSKFKIEMATKNFASSGLLEYITQIEGDAGSVLSDAADASFDMIFLDSERSEYVGWWPDLKRVLRNGGLLVVDNATSHAEEMTPFIKLIQADADFVTSLVPLGNGEFLATKEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXV5</accession>
    <name>A0A2S9GXV5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2612</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92557">
        <property type="protein sequence ID" value="PRC92557"/>
        <property type="gene ID" value="S2091_2612"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.429.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037479">
        <property type="entry name" value="Tauto_MSAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014347">
        <property type="entry name" value="Tautomerase/MIF_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38460">
        <property type="entry name" value="PTHR38460"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14552">
        <property type="entry name" value="Tautomerase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55331">
        <property type="entry name" value="SSF55331"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="126" mass="14036" checksum="931029DDEE45CE29" modified="2018-07-18" version="1">MPLVTITVKKPKTTEFKSTVLNAVHTALVTSGVPVADRFQRVLELDADDFRYDPSYPDVQGVRNDDFVVIEILLSVGRSVKVKKSILATIMSELKAAQFDPENVLVCFKETAWENWAFAGGRIIHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GY07</accession>
    <name>A0A2S9GY07_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase</fullName>
            <ecNumber evidence="4">2.7.7.60</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_2654</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>2-C-methyl-D-erythritol 4-phosphate + CTP + H(+) = 4-CDP-2-C-methyl-D-erythritol + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:13429"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <dbReference type="ChEBI" id="CHEBI:57823"/>
            <dbReference type="ChEBI" id="CHEBI:58262"/>
            <dbReference type="EC" id="2.7.7.60"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via DXP pathway; isopentenyl diphosphate from 1-deoxy-D-xylulose 5-phosphate: step 2/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.60" evidence="4"/>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92599">
        <property type="protein sequence ID" value="PRC92599"/>
        <property type="gene ID" value="S2091_2654"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00056">
        <property type="reaction ID" value="UER00093"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050518">
        <property type="term" value="F:2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019288">
        <property type="term" value="P:isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd02516">
        <property type="entry name" value="CDP-ME_synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001228">
        <property type="entry name" value="IspD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034683">
        <property type="entry name" value="IspD/TarI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018294">
        <property type="entry name" value="ISPD_synthase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01128">
        <property type="entry name" value="IspD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00453">
        <property type="entry name" value="ispD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01295">
        <property type="entry name" value="ISPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword evidence="7 9" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009789"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012526"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00019056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC92599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="221" mass="24283" checksum="1B020736088CBC0F" modified="2018-07-18" version="1">MMADCPKQYLQIAGQSILQHSVNAFLQHDQIHHVFVVVSRDDAYVAQELQADPRLNVLFCGGATRSESVTNGLLAMKNTSHAQDWVLVHDAARPGLNSALISRLIDTVGQDEVGGLLALPVVDTVKFQAPNLENKSEKNIVSTIPRAGLWLAQTPQMFRHAQLLAALNSCKEVTDEASAIEACGLMPKLVEGHWCNTKITRPDDLALVETCLINKHQFKIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GY14</accession>
    <name>A0A2S9GY14_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">HD domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2672</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92617">
        <property type="protein sequence ID" value="PRC92617"/>
        <property type="gene ID" value="S2091_2672"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="166" mass="18179" checksum="28B2251D2B480CC4" modified="2018-07-18" version="1">MMFARDAHKNQVRKYTGNPYADHLAEVAGIVATVAVIVTITQSVTINEMIATAWLHDCVEGCGVELSEIEQLFGLKVALGVSGLSDMETGNRAERKQKSRDRLAACSSWIQTIKCADLISNTSSIVKHDSAFAKVYLEEKRLLLDVMTKADPRLLALARQLSEVTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GY18</accession>
    <name>A0A2S9GY18_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 6">GTPase Era</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">era</name>
        <name evidence="12" type="ORF">S2091_2664</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 8 9">Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92609">
        <property type="protein sequence ID" value="PRC92609"/>
        <property type="gene ID" value="S2091_2664"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070181">
        <property type="term" value="F:small ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042274">
        <property type="term" value="P:ribosomal small subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04163">
        <property type="entry name" value="Era"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00367">
        <property type="entry name" value="GTPase_Era"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030388">
        <property type="entry name" value="G_ERA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005662">
        <property type="entry name" value="GTP-bd_Era"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004044">
        <property type="entry name" value="KH_dom_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009019">
        <property type="entry name" value="KH_sf_prok-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42698">
        <property type="entry name" value="PTHR42698"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07650">
        <property type="entry name" value="KH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54814">
        <property type="entry name" value="SSF54814"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00436">
        <property type="entry name" value="era"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51713">
        <property type="entry name" value="G_ERA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50823">
        <property type="entry name" value="KH_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 6 8" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 6 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="4 6 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Era-type G" evidence="11">
        <location>
            <begin position="15"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="domain" description="KH type-2" evidence="10">
        <location>
            <begin position="213"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="G1" evidence="8">
        <location>
            <begin position="23"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="G2" evidence="8">
        <location>
            <begin position="49"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="G3" evidence="8">
        <location>
            <begin position="70"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="G4" evidence="8">
        <location>
            <begin position="131"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="G5" evidence="8">
        <location>
            <begin position="161"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="23"/>
            <end position="30"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="70"/>
            <end position="74"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="131"/>
            <end position="134"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00020484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51713"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PRC92609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="304" mass="33938" checksum="EF572D7A82B0A2D3" modified="2018-07-18" version="1">MTDTPQIDLSADDFRCGYIAIVGRPNVGKSTLMNALIGAKVSITSRKAQTTRHRITGIQTKDQTQFVYVDTPGFQTKHSNALNRTLNRTVTTTLTAVDVVLYVIEAGMFSQADILVLELLPKNIPCILVINKADHIKDKAVLMPFAAQVASRFNFAAIVPVSARQGFQLESLEAEVKKLLPVNPPMFAEDDITDKSEKFLAAEIVREKVFRFVGDELPYTSTVLVEKFEQEGNLRRVFIAILVDRDGHKAMLIGKKGERLKEISTQSRQDMEKLFGGPVYLEIWVKIKSGWADNEAGLRAYGYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GY74</accession>
    <name>A0A2S9GY74_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2713</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92658">
        <property type="protein sequence ID" value="PRC92658"/>
        <property type="gene ID" value="S2091_2713"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="112" mass="12902" checksum="8FDB9192B3859220" modified="2018-07-18" version="1">MKNYALGRLKQGVMNKTEAAYAAHLELLKHAGDVLWYKFEGVKFRLADATFYSPDFAVLTKNNELQIHEIKGFWQDDAKVKIKVASDLYPFRFIAVYAIPKKNGGGWRQEDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYE6</accession>
    <name>A0A2S9GYE6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2458</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92728">
        <property type="protein sequence ID" value="PRC92728"/>
        <property type="gene ID" value="S2091_2458"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="75"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="113"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="143" mass="16675" checksum="330571A4F6F06897" modified="2018-07-18" version="1">MIILFYLVLKFAVYSVLCGYFYRFYGASGPVKNAYDFGLMWGGIRFLIGLIFAVPFGLALGYLNLLIRREIVESLLPFTLAYLVCFFIFRFIEWRLLFFAMHKKYPKKSIQPVFKMVAMGMVATLFTDLVVMVTVNYIPKFFC</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYI1</accession>
    <name>A0A2S9GYI1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2446</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92716">
        <property type="protein sequence ID" value="PRC92716"/>
        <property type="gene ID" value="S2091_2446"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010699">
        <property type="entry name" value="DUF1275"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06912">
        <property type="entry name" value="DUF1275"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="64"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="97"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="129"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="196"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="221"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="245" mass="26331" checksum="12DA4ED6CEB6DB18" modified="2018-07-18" version="1">MPITYLAHLTSPQRTAKSNLHLGVTLAFVAGALNAGGFLAIGQYTSHMSGIVSSAADNLALGNIVLTLSALFSLFAFICGSASTALLVNYAKRHSVIYIYTPTLILEALLLLVFGLIGKKLQQHELVQVSLTAILLCYVMGLQNALITKISNAEIRTTHITGLVTDIGIELGKLIYWNRDQQQPVHGEVLANRDKLKIYCSLVLFFFCGGVFGALGFKNLGFISTVPLAIVLIALSVAPAFTHKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYJ6</accession>
    <name>A0A2S9GYJ6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">FAD dependent oxidoreductase TIGR03364</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2508</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92778">
        <property type="protein sequence ID" value="PRC92778"/>
        <property type="gene ID" value="S2091_2508"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017741">
        <property type="entry name" value="FAD-dependent_OxRdtase_HpnW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03364">
        <property type="entry name" value="HpnW_proposed"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DAO" evidence="1">
        <location>
            <begin position="8"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="374" mass="40017" checksum="D9354FDB2E1C952D" modified="2018-07-18" version="1">MSVVSAHRVAIIGSGIVGLAHAWAASLRGDAVTVYERDTQAVGASVRNFGLGLVLGQPQGELYDMALRSRAMWLEFFRDTDCWHKAQGSLTVARTPAELAVIEAFQQECGAAYGTKLMNAAEVATHHATGLGGLYSGTEIALESRYAMGILAKWLAVRHGVKFEYGVQVNAIELPKLHSSTGIHYADQVVICSGHDFQTLYPQHYANLGAGVGIKRCALQMLRVANPGIQLAPALMTGLSTLRYEAYTECKALAEPLAALRAEVERTAPALLEHDIHLIVQQVGARGDLLIGDSHVHSETVSPFSRTDIDALILGLAENLLGRSLSVLEHWQGVYASGPNAYELITPAEHVLGVVITGGTGMSISFALAQKNLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYQ8</accession>
    <name>A0A2S9GYQ8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2568</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92838">
        <property type="protein sequence ID" value="PRC92838"/>
        <property type="gene ID" value="S2091_2568"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015708633" evidence="1">
        <location>
            <begin position="22"/>
            <end position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="361" mass="39484" checksum="DD70C724DE926BBB" modified="2018-07-18" version="1">MTSRLLLLLISFLLPCTLVRADVIDHDNSGKTTIVGNSSSEVALPNIPEPAPIDASLMPTQSGSLQFKGALDGARFSVMQDFKGEKGASLDVDFTTQKIPETTLGWLVSAKPDQAETVMNMGWRFGANQQLIFSLAQLHGTVNVDSDGNHNLNLNQFSSGLNYRYFIDKRWFTGLEFSGYTSASQSQFLPTATVSGDNQQHIAGSSLYGMRVGLETSPLPDAKLKIGIGSERLSYDSLSGTDPILSVNTSIKWSQVLFPTVKYNASLEGNAQERNLSTGFDFNLRDGHQLGVKLAHTQWNDGQISDNAIRFAYTYQFGKKFKPFLSQASKAPWNSSLVPEVLERPGYLPNSVLSKPDSSLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYT7</accession>
    <name>A0A2S9GYT7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major Facilitator Superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_2301</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92884">
        <property type="protein sequence ID" value="PRC92884"/>
        <property type="gene ID" value="S2091_2301"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="51"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="83"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="108"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="141"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="168"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="220"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="257"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="289"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="313"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="346"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="369"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="13"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC92884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="412" mass="44727" checksum="CF51EA8A6E05CC8E" modified="2018-07-18" version="1">MYATSKINQLNRATLLFPFALVLFEFAVYIANDMAQPAMLMVTQEFGVDASWVPLSMTAFLIGGASLSWLTGPLSDRIGRRPVLLGGILYFILACLATYLVSSIEAFMALRVLQGIGLCFINAVGYAAVQEAFEEKSAVKVTAMMANVALIAPMAGPLAGAALIQLAPWRSCFLFIAAVSFISLVGLWRKMPETVNLHSKKLPFSSIGRDYLHLFSQRRFVLSALTIPLISMPLIGWIALSPVLLVNDYGMSLMEYGFWQLPILGSLVVGNVCVIFLTDRWPLGRSALLGIWPILLGILIALFGVLVKSASPVYLVIGISLIAFAEGLSFAVLYRFTLMSSEIAKGSVSAGLSMLTMGCYAIGIELMRLAYVAWGITGFTAMLVVAACAFILISQPRIRHEMAIRADNLLIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYV0</accession>
    <name>A0A2S9GYV0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">AAA domain (Cdc48 subfamily)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_2316</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92899">
        <property type="protein sequence ID" value="PRC92899"/>
        <property type="gene ID" value="S2091_2316"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019489">
        <property type="entry name" value="Clp_ATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001270">
        <property type="entry name" value="ClpA/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028299">
        <property type="entry name" value="ClpA/B_CS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07724">
        <property type="entry name" value="AAA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00300">
        <property type="entry name" value="CLPPROTEASEA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01086">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00871">
        <property type="entry name" value="CLPAB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="2">
        <location>
            <begin position="337"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="domain" description="ClpB_D2-small" evidence="3">
        <location>
            <begin position="519"/>
            <end position="610"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC92899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="618" mass="69210" checksum="260649BB8105E0FA" modified="2018-07-18" version="1">MTLPLPRWQLDLERLLPIRSQFVISGSIHDSFLAATDSGATLVPFIRALWESLKARDYQFLLIYDPTDGVRVYPDELAARESAEKLFDVKLKTGNQIVSLETLTNIMKNLVSQREARCALVIDFASRLSREAAHLSEAEYRFFIAAEKLALTSSPIVTLNAANRVGEHQRPLYNPVLWLVNRAQDLPTWYTLDNERIASLAIGKPDYETRHASAQQLAPLFAGYSVASTAAQTQFLNRFAEGSEGMSLTALSDITELADRQLLGISDIDDAVRCYQLGALDNPWRKDYLREKIRDALPFIEERVKGQHPAVVKTLDILKRSVMGLTGAQAKSSGSRPRGVLFFAGPTGVGKTELAKTLTQLVFGDERAYLRFDMSEFAEQHSGARLLGAPPGYVGFDAGGELTNAVREKPFSVVLFDEIEKAHPQILDKFLQILEDGRLTDGRGETAYFSETILVFTSNLGVFVEDRQGVRQQQVKADDPYELVETKIRSSIEDYFKFKLARPELLNRIGDNIVVFNFITPDVAERIFDGMLKNIARRLYEQFKLQLSMPSTVRSALLERCVRDLSNGGRGIGNALEAAFINPLSRALFEHDLDGRQRLVVSQLSEQDKVIELTLEIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZ36</accession>
    <name>A0A2S9GZ36_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2384</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92967">
        <property type="protein sequence ID" value="PRC92967"/>
        <property type="gene ID" value="S2091_2384"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="182" mass="20173" checksum="AAE3AB22F1792815" modified="2018-07-18" version="1">MTSKKMLGSQVKRLLSGVSDHGRQHLLEVETDLVQTAFLLGEAVEKLGASFFALHAAVSAQQQEVDILLADFDATNPKIERLKLLQEEIAQHTNGAVTGLQFQDLTSQLLARTVQRIIGLRNVLSELEVEGSVLPNEGEEDEIVDMLNQINKNLNVQSSELKDLLRKAVHQKDMDCGDIEVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZ38</accession>
    <name>A0A2S9GZ38_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protein-glutamate methylesterase/protein-glutamine glutaminase</fullName>
            <ecNumber evidence="5">3.1.1.61</ecNumber>
            <ecNumber evidence="5">3.5.1.44</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">cheB</name>
        <name evidence="10" type="ORF">S2091_2390</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>H2O + L-glutaminyl-[protein] = L-glutamyl-[protein] + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:16441"/>
            <dbReference type="Rhea" id="RHEA-COMP:10207"/>
            <dbReference type="Rhea" id="RHEA-COMP:10208"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29973"/>
            <dbReference type="ChEBI" id="CHEBI:30011"/>
            <dbReference type="EC" id="3.5.1.44"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>[protein]-L-glutamate 5-O-methyl ester + H2O = H(+) + L-glutamyl-[protein] + methanol</text>
            <dbReference type="Rhea" id="RHEA:23236"/>
            <dbReference type="Rhea" id="RHEA-COMP:10208"/>
            <dbReference type="Rhea" id="RHEA-COMP:10311"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17790"/>
            <dbReference type="ChEBI" id="CHEBI:29973"/>
            <dbReference type="ChEBI" id="CHEBI:82795"/>
            <dbReference type="EC" id="3.1.1.61"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="5">Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.</text>
    </comment>
    <comment type="PTM">
        <text evidence="5">Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the CheB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.61" evidence="5"/>
    <dbReference type="EC" id="3.5.1.44" evidence="5"/>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92973">
        <property type="protein sequence ID" value="PRC92973"/>
        <property type="gene ID" value="S2091_2390"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000156">
        <property type="term" value="F:phosphorelay response regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008984">
        <property type="term" value="F:protein-glutamate methylesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050568">
        <property type="term" value="F:protein-glutamine glutaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018277">
        <property type="term" value="P:protein deamination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006482">
        <property type="term" value="P:protein demethylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd16432">
        <property type="entry name" value="CheB_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00099">
        <property type="entry name" value="CheB_chemtxs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008248">
        <property type="entry name" value="CheB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035909">
        <property type="entry name" value="CheB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000673">
        <property type="entry name" value="Sig_transdc_resp-reg_Me-estase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01339">
        <property type="entry name" value="CheB_methylest"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000876">
        <property type="entry name" value="RR_chemtxs_CheB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52738">
        <property type="entry name" value="SSF52738"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50122">
        <property type="entry name" value="CHEB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5 6" id="KW-0145">Chemotaxis</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 5 7" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="8">
        <location>
            <begin position="4"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="CheB-type methylesterase" evidence="9">
        <location>
            <begin position="159"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="active site" evidence="5 6">
        <location>
            <position position="171"/>
        </location>
    </feature>
    <feature type="active site" evidence="5 6">
        <location>
            <position position="197"/>
        </location>
    </feature>
    <feature type="active site" evidence="5 6">
        <location>
            <position position="293"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="5 7">
        <location>
            <position position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC92973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="358" mass="38549" checksum="CEC6E29407D7D10B" modified="2018-07-18" version="1">MAIKVLIVDDSALIRSVLTEIISSQPDMEVVGVAPDPLVAREMIKKTNPDVLTLDVEMPKMDGLEFLEKLMRLRPMPVLMVSSLTERGSEITMRALELGAVDFVTKPKISIQSGMMDYAEIIADKIRIVAKARVRTRAQFLADVSQRTSGSLPALRSPLISSEKLIIVGASTGGTEAIKSFLLKMPADCPGILITQHMPEGFTKSFAKRLDTLCQISVNEAEGGERILPGHAYIAPGHSHLLLARSGANYITQLSSDEPVNRHRPSVDVLFRSAAKNAGKNAVGVILTGMGKDGAAGMLEMREAGSYNFAQDEASCVVFGMPREAIAVGATHEVAPLNDLSKLVLNYLATQGGRSLRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZU4</accession>
    <name>A0A2S9GZU4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1975</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93237">
        <property type="protein sequence ID" value="PRC93237"/>
        <property type="gene ID" value="S2091_1975"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032307">
        <property type="entry name" value="PepSY_TM-like_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40115">
        <property type="entry name" value="PTHR40115"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16357">
        <property type="entry name" value="PepSY_TM_like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="185"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="215"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="236" mass="25931" checksum="59B7368C1C1659D7" modified="2018-07-18" version="1">MNNPQLKHLHSVNHTNGVINSVVTNVLHDKRSKRSIFLKWLRKLHGWIGLWGAALGLLFGVTGILQNHRTILKIPAAQAQETMLQLPLPMPAPADAQALANWLQHELAFDRVATKVRSEPQKTVAWGDKSMKQPAHWSAVFSSPSVNFQAEYWLGNNFVSVKRSDNNIFASLNSLHKGNGVGIGWILLADTVAGSIIFLSLTGVLLWSLLNRRRMIGAGIGLTSLAIGIALAWQAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZZ5</accession>
    <name>A0A2S9GZZ5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Rod shape-determining protein MreD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_2006</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MreD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93268">
        <property type="protein sequence ID" value="PRC93268"/>
        <property type="gene ID" value="S2091_2006"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007227">
        <property type="entry name" value="Cell_shape_determining_MreD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026034">
        <property type="entry name" value="MreD_proteobac"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37484">
        <property type="entry name" value="PTHR37484"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04093">
        <property type="entry name" value="MreD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018472">
        <property type="entry name" value="MreD_proteobac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03426">
        <property type="entry name" value="shape_MreD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-0133">Cell shape</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="56"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="106"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="135"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC93268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="170" mass="19237" checksum="4B9412C30F772B4D" modified="2018-07-18" version="1">MNRPHYILLPASSAFIFISLLLTFLLNFLPWGTMIGVPDFVALTLVFWSIHQPRKVGIGVAFAMGLLMDVHTASLLGENALAYTLLSYFAITIHRRVLWFTPMTQALHVFPLFLLTEIIRAVIQLCVNGKFPGWLFFVESAVTAALWPLATWILLAPQRRTVNRDDTRPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H027</accession>
    <name>A0A2S9H027_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Enoyl-CoA hydratase/carnithine racemase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2073</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the enoyl-CoA hydratase/isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93335">
        <property type="protein sequence ID" value="PRC93335"/>
        <property type="gene ID" value="S2091_2073"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.12.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014748">
        <property type="entry name" value="Enoyl-CoA_hydra_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="264" mass="28697" checksum="C2FC1D07C9B12B79" modified="2018-07-18" version="1">MTYQTLLVEIARGAATVTLNRPEVRNAFNEVVIAELTEVFQELGQNSEVRVIVLAANGPSFCAGADLNWMKKMATYTPEENLADAEQLAEMLYQIFGCPKPVIAKVQGDCYAGGMGLAAACDISVAVESAQFCLSEVKLGLIPATISPYVIKAMGANAARRYFITAERFSAKEAHRIGFVHEVVAAEQLDETVAQLVNAIVNNSPNAVIEAKWLVEDVTSAEIDEDLLAYTAERIAAIRTSEEGREGVASFLEKRKPNWLLPVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H067</accession>
    <name>A0A2S9H067_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1758</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93371">
        <property type="protein sequence ID" value="PRC93371"/>
        <property type="gene ID" value="S2091_1758"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="55"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="99"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="156"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="99"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="170"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="303" mass="33557" checksum="795A76B401D8CF7B" modified="2018-07-18" version="1">MLPRFSIAKQRTASIDTVLLNMSWGTLEFGFTISKKPLVSDFEDELYPHQRSRNLFAIIFMALVHLIVIYFLLLNKTEPPLKQGEEAGQLVFFDLQGKKDGAQKPKPAKTQPEKKQQQKQPRNPNAIAAAPQAVVSPPTNSPVAAPPVVDTMSQIAAARERRRASEAEAAEQNSEAQAASNGPSENDIAMARIKANIQAANYSRKGTNGVFQILRKGVQNGSFSFRGWTNDPRQSSHQTYEVDAGIGGDVKLAIIRKMIELIREHYTGDFNWESQRLGRVVPLSARPADNAGLEAFLMKEFPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H083</accession>
    <name>A0A2S9H083_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Aminotransferase</fullName>
            <ecNumber evidence="4">2.6.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_1781</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 4">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.-" evidence="4"/>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93394">
        <property type="protein sequence ID" value="PRC93394"/>
        <property type="gene ID" value="S2091_1781"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901605">
        <property type="term" value="P:alpha-amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000796">
        <property type="entry name" value="Asp_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004838">
        <property type="entry name" value="NHTrfase_class1_PyrdxlP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11879">
        <property type="entry name" value="PTHR11879"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00799">
        <property type="entry name" value="TRANSAMINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00105">
        <property type="entry name" value="AA_TRANSFER_CLASS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="5">
        <location>
            <begin position="35"/>
            <end position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC93394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="404" mass="43851" checksum="C48B926F8EFB83D0" modified="2018-07-18" version="1">MTSTSTPSLFTAIELAPRDPILGITEAYNADTNPKKVNLGVGVYYDDNGKVPLLECVQRAEALLIATVTPRTYLPIDGLATYDKAVQELVFGAESKVIAEKRVITAQAIGGTGALKLGADFLKRFAPDAQVWISDPSWENHRALFESAGFVVNNYPYYDAATHGVDFESMLASFKTMPAGSIVLLHACCHNPTGADLNADQWSKIIEVVTSRGLVPFLDMAYQGFGEGIETDGQVVRRFAAAGGPLFVSNSFSKSFSLYGERVGALSIVATDSAEAARVLSQLKRIIRTNYSNPPTHGGKVVATVLSNPELRALWETELAAMRVRIRANRELLVDLLKQKAPSHDFAFVKQQCGMFSYSGLSKEQVDQLRNNNAIYAVDTGRICVAALNSSNINYVVDAICQVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0C3</accession>
    <name>A0A2S9H0C3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Ribose/xylose/arabinose/galactoside ABC-type transport systems permease component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_1795</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93408">
        <property type="protein sequence ID" value="PRC93408"/>
        <property type="gene ID" value="S2091_1795"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001851">
        <property type="entry name" value="ABC_transp_permease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02653">
        <property type="entry name" value="BPD_transp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="53"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="76"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="103"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="126"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="155"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="194"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="246"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="325"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC93408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="351" mass="37474" checksum="E4C81B412E243B99" modified="2018-07-18" version="1">MLKQFQTLAVQTMNSSHSSDPNPEHDMRVHSSEQPFVPADKQRRWLVEYSMPIGYAVLFILLSFTVENFFSTTNIIGLMLSVAQIGMVACTMMLCLASRDFDLSVGSTIAFAGVLGAIILEQTHSVALTVIGGLLAGALIGAGNGVLIAYLRVNALIATLATMLMVRGLAFIVSHGQAVGIANEDFISFGDTRLLGLPLPILVTAACFVVFGVLLNHTVFGRNTLAIGGNPEAARLAGVKVERLRVWIFLLQGLITAMAGLILASRITSGQPNAAQGFELDVISACVLGGVSLQGGKARIFGVLIGVLIMGTLENVMNLMDVDAFYQYLMRGLILLIAVLLDQLKTTAHRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0K5</accession>
    <name>A0A2S9H0K5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="14">OmpA-like transmembrane domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">S2091_1902</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell outer membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the outer membrane OOP (TC 1.B.6) superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93515">
        <property type="protein sequence ID" value="PRC93515"/>
        <property type="gene ID" value="S2091_1902"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046930">
        <property type="term" value="C:pore complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015288">
        <property type="term" value="F:porin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006811">
        <property type="term" value="P:ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07185">
        <property type="entry name" value="OmpA_C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011250">
        <property type="entry name" value="OMP/PagP_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006664">
        <property type="entry name" value="OMP_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006665">
        <property type="entry name" value="OmpA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036737">
        <property type="entry name" value="OmpA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000498">
        <property type="entry name" value="OmpA-like_TM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00691">
        <property type="entry name" value="OmpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01389">
        <property type="entry name" value="OmpA_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01021">
        <property type="entry name" value="OMPADOMAIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103088">
        <property type="entry name" value="SSF103088"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56925">
        <property type="entry name" value="SSF56925"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51123">
        <property type="entry name" value="OMPA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0626">Porin</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0732">Signal</keyword>
    <keyword evidence="5 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1134">Transmembrane beta strand</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015467477" evidence="12">
        <location>
            <begin position="26"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="domain" description="OmpA-like" evidence="13">
        <location>
            <begin position="257"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="PRC93515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="386" mass="41785" checksum="EE1FCBA7F738901D" modified="2018-07-18" version="1">MKCTRTLKNLSLIAFSAIAIPYAAAQENTTTQDTSAWYGGLNVGQSRAKIDDASITNRLLTEGASAMSINNNDRDTGFKIFGGYQFNKNFSIESGYFDLGKFGYSATTTPPGTLNGSITLRGLNIDAIGFLPFTENFSGFGRLGLNYSQAKDSFSGSGLAAVASSDPGKHDLNYKVGMGLQYRLTQALAMRAEVERYRVDDAIGNKGDIDLYSIGLVYRFGEKTQMHAAVYRPAAPAPIPEPTPEVVVVINQPPAPPPPIKVVFAADSMFDFNRADMRSDGKRFLDEFSANLKSASFDLISVTGHTDRIGSHDYNMKLSTRRAEAVKSYLVEVAGIPSNKIDAKGVDGVDPVTKPEECKGNKVTKALIACLQPDRRVEVEVTGTKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0S2</accession>
    <name>A0A2S9H0S2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Enoyl-CoA hydratase/carnithine racemase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1580</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93579">
        <property type="protein sequence ID" value="PRC93579"/>
        <property type="gene ID" value="S2091_1580"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="259" mass="28027" checksum="3C94C167CAB22576" modified="2018-07-18" version="1">MDILTNKENSILTITFNRPEKKNAITGAMYQTMADALRAAETDNEVRVILLTGSDSIFTAGNDLEDFMKNAAQFVSGDAENTPVVQFMRALSSAQKPVIAAVAGLGVGIGTTLLMHCDLVYLADNAKLTMPFSQLGLCPEFSSSILLQKIAGYHRAAEKLMLGEAFSAQEALEMGMANKVVPAAELLAYANQQASKLVALPAASLRATKRLMKASQTSLVNEVMQGELQQFGKMLNGPEAKEAFMAFFQKRKPDFSQFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0Z2</accession>
    <name>A0A2S9H0Z2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Efflux transporter, RND family, MFP subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_1655</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93654">
        <property type="protein sequence ID" value="PRC93654"/>
        <property type="gene ID" value="S2091_1655"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006143">
        <property type="entry name" value="RND_pump_MFP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01730">
        <property type="entry name" value="RND_mfp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="domain" description="HlyD_D23" evidence="4">
        <location>
            <begin position="85"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="367"/>
            <end position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC93654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="400" mass="42873" checksum="A5D96BEB5872175F" modified="2018-07-18" version="1">MSSNEIKTPAPRRLPGNLKVIALIIVAIAGAVVAYGLISRSRDKAALVSQAQERLIPIVKVIQPASRADAQPLTLPGTLQAFYSATVYARVSGYLKHWSVDIGAPVKSGQQLADIETPELDQQLKQSEANLETALANERLTEITSKRWQHLLASDSVSQQEADEKSGDYDAKKALSSAARADVDRLRVLESFKRITAPFDGVVTARKTDIGALINAGHDSGHELFTVADVHKLRLYVNVPQSYANLIQVGMKAKLDVPEHPGQTFDALLANNSRSVSEGSGTILVELEVDNKDGKLLPGEYGNVHFDLPRDMKAVQVPASALSFRKEGLTIATLTPDNRVAFRVVKISHDLGTVVEIDSGLAATDRLIDNPPDSLENGDQVRPAAEPAPSSTASAGGAKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0Z5</accession>
    <name>A0A2S9H0Z5_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">3-demethoxyubiquinol 3-hydroxylase</fullName>
            <shortName evidence="7">DMQ hydroxylase</shortName>
            <ecNumber evidence="7">1.14.99.60</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">coq7</name>
        <name evidence="8" type="ORF">S2091_1652</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol during ubiquinone biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>a 6-methoxy-3-methyl-2-all-trans-polyprenyl-1,4-benzoquinol + AH2 + O2 = A + a 3-demethylubiquinol + H2O</text>
            <dbReference type="Rhea" id="RHEA:50908"/>
            <dbReference type="Rhea" id="RHEA-COMP:10859"/>
            <dbReference type="Rhea" id="RHEA-COMP:10914"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:84167"/>
            <dbReference type="ChEBI" id="CHEBI:84422"/>
            <dbReference type="EC" id="1.14.99.60"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
        <text evidence="7">Binds 2 iron ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="7">Cofactor biosynthesis; ubiquinone biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the COQ7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.99.60" evidence="7"/>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93651">
        <property type="protein sequence ID" value="PRC93651"/>
        <property type="gene ID" value="S2091_1652"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00232"/>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008682">
        <property type="term" value="F:3-demethoxyubiquinol 3-hydroxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006744">
        <property type="term" value="P:ubiquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01042">
        <property type="entry name" value="DMQH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01658">
        <property type="entry name" value="COQ7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012347">
        <property type="entry name" value="Ferritin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011566">
        <property type="entry name" value="Ubq_synth_Coq7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11237">
        <property type="entry name" value="PTHR11237"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03232">
        <property type="entry name" value="COQ7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="SSF47240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 7" id="KW-0408">Iron</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0830">Ubiquinone</keyword>
    <keyword evidence="1 7" id="KW-0831">Ubiquinone biosynthesis</keyword>
    <feature type="binding site" evidence="7">
        <location>
            <position position="67"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="97"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="100"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="149"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="181"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="184"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC93651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="218" mass="23705" checksum="6380A7C594EDBB12" modified="2018-07-18" version="1">MIGNDLLNKTDLFIAMLDKSLRVVNGVATDSRPNPAKKIIENSADSQLDDKERRHSAGLMRVNHVGEVCAQALYQSQGLFSHSKELQLQFVQAGREEEDHLAWTAHRISELGSHLSLLNPLWYAGAFVCGAIAAKVGDAASLGFVVETERQVEAHLNSHLTNLPANDVKSRAIVEQMRDDEIAHGAAAQALGAADLPLPVKHLMTGMAKVMTTVAYYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0Z9</accession>
    <name>A0A2S9H0Z9_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Homoserine kinase</fullName>
            <shortName evidence="3">HK</shortName>
            <shortName evidence="3">HSK</shortName>
            <ecNumber evidence="3">2.7.1.39</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">thrB</name>
        <name evidence="5" type="ORF">S2091_1663</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>ATP + L-homoserine = ADP + H(+) + O-phospho-L-homoserine</text>
            <dbReference type="Rhea" id="RHEA:13985"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57476"/>
            <dbReference type="ChEBI" id="CHEBI:57590"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.39"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 4/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the pseudomonas-type ThrB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.39" evidence="3"/>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93662">
        <property type="protein sequence ID" value="PRC93662"/>
        <property type="gene ID" value="S2091_1663"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00050">
        <property type="reaction ID" value="UER00064"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004413">
        <property type="term" value="F:homoserine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009088">
        <property type="term" value="P:threonine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd05153">
        <property type="entry name" value="HomoserineK_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00301">
        <property type="entry name" value="Homoser_kinase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005280">
        <property type="entry name" value="Homoserine_kinase_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00938">
        <property type="entry name" value="thrB_alt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 5" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0791">Threonine biosynthesis</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="APH" evidence="4">
        <location>
            <begin position="27"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00301"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC93662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="312" mass="35116" checksum="2CA9A8C2FF48119E" modified="2018-07-18" version="1">MAVFTPVSLADLSAWLLQFPLGRAHAIKGISSGIENSNFFITTDAGDYVLTIFENLSFEQLPFYLHLMDHLAQRGILVPAPVANNAGQLVSLLHGKPAAIVSKLSGTSQMEPSPLHCGEVGTMLAKMHLAGQDYDLQQDNLRGLAWWTETAPKVRDFLSPEQLQLLSSELQHQQTYAASAPYQTLARGPIHADLFRNNVMFDGTRLTGFFDFYFAGWDTLIFDLAVTINDWCIHLESGELDPARVSALLNAYQQVRPLSTEEQSAWPTMLRGAALRFWLSRLFDFYQPREAHMLTPHDPAHFERILRKRCEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H104</accession>
    <name>A0A2S9H104_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putative divalent heavy-metal cations transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_1649</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93648">
        <property type="protein sequence ID" value="PRC93648"/>
        <property type="gene ID" value="S2091_1649"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046873">
        <property type="term" value="F:metal ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003689">
        <property type="entry name" value="ZIP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02535">
        <property type="entry name" value="Zip"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="29"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="139"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="166"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="199"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC93648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="223" mass="24247" checksum="98A5349250388273" modified="2018-07-18" version="1">MVSLSVGIMLSTAFLHALPEAFESQADTHGLFALLLGSLLGFFLLEKFAILRHSHHHEGDGHHHAHGHDAREAGKSGWMILVGDGMHNFTDGILIAAAFLANPQLGIVTGLAIIAHEIPQEIGDFIVLLNAGFTRRRAYMYNLISSLMAVVGGVLGYYTLESASNLIPYVLVIASSGFIYIAVSDLMPQMQRRATMRETIPQIILISIGVLIVLFLTGQQHSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H123</accession>
    <name>A0A2S9H123_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Signal recognition particle receptor FtsY</fullName>
            <shortName evidence="5">SRP receptor</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ftsY</name>
        <name evidence="8" type="ORF">S2091_1686</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Peripheral membrane protein</topology>
            <orientation evidence="5">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the GTP-binding SRP family. FtsY subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93685">
        <property type="protein sequence ID" value="PRC93685"/>
        <property type="gene ID" value="S2091_1686"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031226">
        <property type="term" value="C:intrinsic component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006614">
        <property type="term" value="P:SRP-dependent cotranslational protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00920">
        <property type="entry name" value="FtsY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013822">
        <property type="entry name" value="Signal_recog_particl_SRP54_hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004390">
        <property type="entry name" value="SR_rcpt_FtsY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036225">
        <property type="entry name" value="SRP/SRP_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000897">
        <property type="entry name" value="SRP54_GTPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042101">
        <property type="entry name" value="SRP54_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43134:SF7">
        <property type="entry name" value="PTHR43134:SF7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00448">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02881">
        <property type="entry name" value="SRP54_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00962">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00963">
        <property type="entry name" value="SRP54_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47364">
        <property type="entry name" value="SSF47364"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00064">
        <property type="entry name" value="ftsY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00300">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 5" id="KW-0675">Receptor</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SRP54" evidence="7">
        <location>
            <begin position="335"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="41"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="169"/>
            <end position="176"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="250"/>
            <end position="254"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="314"/>
            <end position="317"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00920"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS00300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC93685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="362" mass="39028" checksum="CA76F5DF12586E46" modified="2018-07-18" version="1">MFSFFKKKPKTDEVANIPASAPQPASQPDSQSASQPILQPILQPHPTPISTPDEILPPPESHSAKQSWLTRLKNGLSKTSNNLTSLFVGAKIDDDLYEELESALLMSDAGMEATLYLLDELKKQVKQQKLTDSEQVKTALKNIFIELLAPLERSLELGRHQPMVMMIAGVNGAGKTTTIGKLAKHLQAHHQSVLLAAGDTFRAAAREQLTVWGERNNVTVISQESGDPAAVAFDSVNSAIAKGINVVMVDTAGRLPSQLHLMEELKKIKRVVTKSMEGAPHQVILVIDGNTGQNALAQVKAFDDALGLTGLVITKLDGTAKGGILAAIAKTRPIPVYFIGVGEKIEDLQPFNAREFVEALLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H152</accession>
    <name>A0A2S9H152_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">PAP2 superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1674</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93673">
        <property type="protein sequence ID" value="PRC93673"/>
        <property type="gene ID" value="S2091_1674"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036938">
        <property type="entry name" value="P_Acid_Pase_2/haloperoxi_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000326">
        <property type="entry name" value="P_Acid_Pase_2/haloperoxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01569">
        <property type="entry name" value="PAP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48317">
        <property type="entry name" value="SSF48317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="SSF52799"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="19"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="57"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="91"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="162"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="214"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="267"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="domain" description="acidPPc" evidence="2">
        <location>
            <begin position="119"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="400" mass="46115" checksum="E67BAE40F606F455" modified="2018-07-18" version="1">MIASSPITAATWSQRLRHLLLNLLVFSLCYQTANWMAESNHIQRNIAFNFETQTPFIAWMIIPYLSSGLFFIGSFFYVTSFGDLRVLSHRIVLATVIATLIFMVYPLQFSLLKPMINTPLYATLFQFLSIADRPYNQFPSLHIAYCVIFWQSLHPNLRQRPARIALAMILLLIAASTLFTYQHHCLDIVGGLLLGLSTLQLIRSDSRQTSVAFYYFIAATIVVLIGSLALTYWFALYISFSLLLVGWAYHRHNRHFLHKKAGQHPLWIWLLFAPYLAGYWITWKLVQYKERQHPAFTQFSQQLWIGRRLTPHEAKQLPSDCVVFDLSPELSEASCLSKQHYWHFPILDLIHPPTQLIAEIAASIHHEIALGRVVYLHCAMGYSRCKLVANHVFSETKAIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1E1</accession>
    <name>A0A2S9H1E1_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ubiquinone biosynthesis accessory factor UbiJ</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">ubiJ</name>
        <name evidence="3" type="ORF">S2091_1414</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Required for ubiquinone (coenzyme Q) biosynthesis. Binds hydrophobic ubiquinone biosynthetic intermediates via its SCP2 domain and is essential for the stability of the Ubi complex. May constitute a docking platform where Ubi enzymes assemble and access their SCP2-bound polyprenyl substrates.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; ubiquinone biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the UbiJ family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93805">
        <property type="protein sequence ID" value="PRC93805"/>
        <property type="gene ID" value="S2091_1414"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00232"/>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032150">
        <property type="term" value="P:ubiquinone biosynthetic process from chorismate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02215">
        <property type="entry name" value="UbiJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038989">
        <property type="entry name" value="UbiJ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38693">
        <property type="entry name" value="PTHR38693"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0831">Ubiquinone biosynthesis</keyword>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="125"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="191" mass="21275" checksum="C5F9BD9B5BE57E58" modified="2018-07-18" version="1">MNPTLLLPALNHLLAQEPWASQKLQLHAGKIACIDMSMFSLRVKVTAQGYLESAPEDATANVTIHVNPADVPLILQDKERAVSYVKLEGDADLAQTISELGKHLRWDAEQQLSQVFGDIAGRRLANTGKAALSSLQANAQKLQENLAEYFLEENPLLVRPARVTEFAQEVGRTRDDVERLLKRIEKLEKAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1J4</accession>
    <name>A0A2S9H1J4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ArgP: transcriptional regulator, ArgP family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1458</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93849">
        <property type="protein sequence ID" value="PRC93849"/>
        <property type="gene ID" value="S2091_1458"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017685">
        <property type="entry name" value="ArgP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03298">
        <property type="entry name" value="argP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="294" mass="32652" checksum="424442B9062BF6AA" modified="2018-07-18" version="1">MNLNPKHTEAFRAVIESGSFEQAAVRLHLTSPAISLRVRALESQLGNALIVRSRPARATRMGQRLMQYLKRAKLLETDLAAELAVQQDAPLTLVLALNADSIGTWFFPALSDVLIRERVLLDLTVEDQDHTYSLLETGLAIGCISTEPKPMRGCSAELLGVMRYWLVASEDFRNRWFPDGLTRKAARKAPVVAYTHKDTLQSSFLLSKLGLPAGAFPCHYVPGSASHFNAIRYGLGYGMVPELLLKAAGKNKMAHLAPAKPLELALYWHTWKVQSPRMENLSRQIIAAARKILK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1L7</accession>
    <name>A0A2S9H1L7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1490</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93881">
        <property type="protein sequence ID" value="PRC93881"/>
        <property type="gene ID" value="S2091_1490"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="SSF103657"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="141" mass="15800" checksum="3F540BB13FF9E5B7" modified="2018-07-18" version="1">MIHQLAESYLSSQAGRDDAVLTSLDQLLVNDTDGKEKDDNIDQLYEQLKKCWEANPDIRSEQIIDYLRKFVAADGSMPYKSIPTHTAALGQVMARFKEDGGADSPIYSALYKGLGFAVVSNGILNSFIRKMTERPEEPEPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1R5</accession>
    <name>A0A2S9H1R5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1540</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93931">
        <property type="protein sequence ID" value="PRC93931"/>
        <property type="gene ID" value="S2091_1540"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="149" mass="16193" checksum="04A6188BE50E9973" modified="2018-07-18" version="1">MSVMPLPVKLPITVWVSALQLPFWLNPVPVLYQVLTTVLPLAAVEVATIAARPSPLTFANRYDAPACHAPRIVLAPWAYALPCAFEYHTLAIACPWAFSQICTKSERPLPSTSPTINCWFNCDAPSDTVIIAPVLGMSASKFIAPLEFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1W5</accession>
    <name>A0A2S9H1W5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1142</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC93969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93969">
        <property type="protein sequence ID" value="PRC93969"/>
        <property type="gene ID" value="S2091_1142"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="111" mass="13191" checksum="10325A0E54CB2336" modified="2018-07-18" version="1">MVESIREIGEKRTSEQRFHISSLTQIHEKSTMPFTHITAAKNQLHWYLDVIFKENACLTWDRNAAENLSITKKNYNEPLTTRYFKKSSAFQKNIFTPHFMSNIMLRYLAYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1Y6</accession>
    <name>A0A2S9H1Y6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Nucleotidyl transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1143</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC93970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93970">
        <property type="protein sequence ID" value="PRC93970"/>
        <property type="gene ID" value="S2091_1143"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005835">
        <property type="entry name" value="NTP_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00483">
        <property type="entry name" value="NTP_transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NTP_transferase" evidence="2">
        <location>
            <begin position="7"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="556" mass="62978" checksum="7087D22043DF889A" modified="2018-07-18" version="1">MQIIIPMSGFGERFRRAGYSVPKPLIEIDGKPIVAHVIDMFPGEKDFIFICNQDHLDDPGYHMESILRHYCPTGRIIGIHPHKLGPIHAVRQVENLIDPDRPVVVNYCDFTCSWDWNHFKQYVAKTACQGAIPAYKGFHPHTLGNTNYAYMREMSGWVQDIQEKQPYTNNRMEEYASSGTYYFITAQIMNEAFRIALEQDLNVGGEYYVSLAYKPLLANNQSVAVYPLQHFMQWGTPEDVAEYNTWSMTFRRLVAPVKGEPKPHGSLIVPMAGLGQRFSNEGYELTKPLIPVSGMSMVAQATHDLPPAEHYVFVVRSDMQGYEDVSTELKRLYPMSIIKTIARVTEGQACTALIGLDALENELDNIPGPITIGTCDNGVLYDSSAFDGLVDNLGVDVIVWGIRGYPNAVRHPKMFGWIDAKEGQISSISVKTPLDNPASDPIVLGTFTFRRGEDFRRAIEHLIARDGRVNGEFYIDSCINDAIELGLRCHLLEVDSYLCWGTPNDLRTFEYWQSCFHKWPGHPYRLELDRRVPKDQLKAIETRCQAILPHLPGRQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H245</accession>
    <name>A0A2S9H245_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1234</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94061">
        <property type="protein sequence ID" value="PRC94061"/>
        <property type="gene ID" value="S2091_1234"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.700">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038656">
        <property type="entry name" value="Peptidase_G1_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015504700" evidence="1">
        <location>
            <begin position="28"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="319" mass="34236" checksum="F55FD951B6C2DBE1" modified="2018-07-18" version="1">MKNIFIKALVISCLASAATISMVSVHAGENQSLVQVAPDEIARVPGMTADYVRTPHGYFHSSCVQHIDQSEELQVDGSIKRADGKLRQVAQCAYPRFLNNGTRIEATAKNTRLPEVYNGYLQLVSATLSSGTNELTAYMTVPPNPSSESGQTLYFFPGLEDAQNVVSILQPVLGWDGYGANNWTIASWNCCKSGTTYVGNNVVVKPGDLIYGTMVNTGGQNWTITATDETNTSLASATLKTQGYSQTFDWVFAGALETYGVSSCSQFPSSGPIKFTNIQAYVGGKVVSNPSWSIQPGSNSETACTKATVVDSKDVNISY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H246</accession>
    <name>A0A2S9H246_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94027">
        <property type="protein sequence ID" value="PRC94027"/>
        <property type="gene ID" value="S2091_1200"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015766708" evidence="1">
        <location>
            <begin position="25"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="160" mass="17142" checksum="A4664493CC3B993A" modified="2018-07-18" version="1">MKIKFIQMAVIVSLTAALSACVVAPQQPIGYRMTSTVLPTYVNGQYVGMQPSNYMPPASAPTYAPAAPTAAAPNSTPTTTTVATNQQPVVVQQAPVYMQSPTPSVVYIQSPAPVVYSSYYDPYYSPVYVNPWYGGIGIGVGIGYYGRWGGGWHGRGGWHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H290</accession>
    <name>A0A2S9H290_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">ATP-dependent RNA helicase DeaD</fullName>
            <ecNumber evidence="6">3.6.4.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Cold-shock DEAD box protein A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">deaD</name>
        <name evidence="6" type="synonym">csdA</name>
        <name evidence="13" type="ORF">S2091_1278</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>ATP + H2O = ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the DEAD box helicase family. DeaD/CsdA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="6"/>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94105">
        <property type="protein sequence ID" value="PRC94105"/>
        <property type="gene ID" value="S2091_1278"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070417">
        <property type="term" value="P:cellular response to cold"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000027">
        <property type="term" value="P:ribosomal large subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006401">
        <property type="term" value="P:RNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd12499">
        <property type="entry name" value="RRM_EcCsdA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00964">
        <property type="entry name" value="DEAD_helicase_DeaD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034415">
        <property type="entry name" value="CsdA_RRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005580">
        <property type="entry name" value="DbpA/CsdA_RNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028618">
        <property type="entry name" value="DEAD_helicase_DeaD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03880">
        <property type="entry name" value="DbpA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 6 8" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 6 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 6 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5 6" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="Q_MOTIF" evidence="12">
        <location>
            <begin position="7"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="10">
        <location>
            <begin position="38"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="11">
        <location>
            <begin position="233"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="440"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="586"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="632"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="7">
        <location>
            <begin position="7"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="440"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="603"/>
            <end position="620"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PRC94105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="776" mass="85490" checksum="4F1F6460B759EFD5" modified="2018-07-18" version="1">MSENSLPSFSELELSDALLRVLNDIGYETPSPIQAATIPLLLANRDVLGQAQTGTGKTAAFALPILSRIDIKQTSPQALVLAPTRELAIQVAEAFQSYATHIPGFHVLPIYGGQSYGPQLSALRRGVHVVVGTPGRVIDHLDKGTLDLSKLKTLVLDEADEMLRMGFIDDVERILKETPESRQTTLFSATMPSAIKRIAQTYLKSPEVITVAAKTGTADNIRQRYWLVSGMHKLDALTRILEAETFDGMIIFARTKLGTEELAGRLQARGFSAAAINGDIQQAQRERTIAQLKDGKIDILVATDVAARGLDVERISHVINYDVPHDPESYTHRIGRTGRAGRSGEAILFITPREKGLLKIIERSTRQPISPLELPSVQAVNDVRIAKFKDQINATIAEGELEQFQAIIEDFEREHNVPAIEIAAALAKIARGDVPLLLDKNKREPRMETMRSDDRPARNDRNDRGDRGDRNDRFERAERPQRERGDRFERSERPARAERERGPRVSEPGMQTYRIEVGHDHGVKPGNIVGAIANEANIDSKNIGRIEIYDGFSVLDLPSDLPKEVMQHLQSVWVAGQQLKISVDGHSEAAPATVSAPAARERSAPVRSEHKRSEKPAEFAKPFARAEVEVRAEPKPTMQPAEVADPKARVKKDKPNTKSKFAVQSYRIEVGRNHDVTPSTIVATIAAQASLEAKHVGRIDIFDTYSVLDLPEGMPQHILDNLKVVKLGGQQLKISHVGAGLINSDKAAQVAQAAKKKSFVGGDSKFVKDKPARKPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2E6</accession>
    <name>A0A2S9H2E6_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">30S ribosomal protein S19</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpsS</name>
        <name evidence="7" type="ORF">S2091_1311</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the universal ribosomal protein uS19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94138">
        <property type="protein sequence ID" value="PRC94138"/>
        <property type="gene ID" value="S2091_1311"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.860.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00531">
        <property type="entry name" value="Ribosomal_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020934">
        <property type="entry name" value="Ribosomal_S15/S19_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002222">
        <property type="entry name" value="Ribosomal_S19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005732">
        <property type="entry name" value="Ribosomal_S19_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023575">
        <property type="entry name" value="Ribosomal_S19_S15_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11880">
        <property type="entry name" value="PTHR11880"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00203">
        <property type="entry name" value="Ribosomal_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002144">
        <property type="entry name" value="Ribosomal_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00975">
        <property type="entry name" value="RIBOSOMALS19"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54570">
        <property type="entry name" value="SSF54570"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01050">
        <property type="entry name" value="rpsS_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00323">
        <property type="entry name" value="RIBOSOMAL_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00015696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC94138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="91" mass="10169" checksum="23DC622AED9C67E6" modified="2018-07-18" version="1">MTRSLKKGPFCDAHLVKKVEAAQAIKDKKPIKTWSRRSTIMPDFIGLTIAVHNGKQHVPVYVSENMVGHKLGEFALTRTFKGHAADKKAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2P9</accession>
    <name>A0A2S9H2P9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Biopolymer transport protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_0880</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Membrane</location>
            <topology evidence="1 6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the exbB/tolQ family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94259">
        <property type="protein sequence ID" value="PRC94259"/>
        <property type="gene ID" value="S2091_0880"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002898">
        <property type="entry name" value="MotA_ExbB_proton_chnl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01618">
        <property type="entry name" value="MotA_ExbB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="120"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="167"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="domain" description="MotA_ExbB" evidence="8">
        <location>
            <begin position="94"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC94259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="240" mass="25823" checksum="C9938F4BBDBE0981" modified="2018-07-18" version="1">MTDLYLNLIAQGAIYALVLFSIITWILIFTKGVQHWRLARHNRTFSKQFWSASSLDAAAALTEIASPKSRLASVGFNALFVNEGGSVSHDLEHSWDRQELLERHLRQQIQKEYQSLESGLAVLASIGSTAPFVGLFGTVFGIIHALSAIGKNASASIDVVAGPIGEALVATGVGIAVAVPAVLAYNFYVRRLKVTAADLDNYATDFVNLAQKNGFRVARNSARSTQTKVQGIASIEGAFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2X9</accession>
    <name>A0A2S9H2X9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Sodium/hydrogen exchanger family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_0837</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94216">
        <property type="protein sequence ID" value="PRC94216"/>
        <property type="gene ID" value="S2091_0837"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015299">
        <property type="term" value="F:solute:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006812">
        <property type="term" value="P:cation transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006153">
        <property type="entry name" value="Cation/H_exchanger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00999">
        <property type="entry name" value="Na_H_Exchanger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="31"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="63"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="95"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="138"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="170"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="198"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="229"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="280"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="308"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="376"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="domain" description="Na_H_Exchanger" evidence="5">
        <location>
            <begin position="11"/>
            <end position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC94216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="414" mass="44753" checksum="A71FF4CF404A8848" modified="2018-07-18" version="1">MTDLFFAAVLVFVCVPTALSRLLRIERIFPLVFLQLVFGLFLSQSGLLGWLKTQHIDFLNGSLGFSLQGLGWLGVVIMIALAGGDSMSGTRNSKAWYFVPISVVGFSVTCTLGGLVGYHLATLYPGVVGSQATPLRSAFALGVTLSVTALPVLIAILRDTGLAASTVGKLAVNCAMLDDIWMWLGIALILSFDSTNGHVVRIFPLLAGYLVLMLLVLRPVLRHRYGSKSATSLNVILVFVSVICFSAMLTDLIGLHPLFGAFIGGAIFPQQVLDQWRESLTSICQVLLLPFYFIMTGMRLQFDISDQAFWLLTTIVTATAVAGKFIGVALAARCSGLPWRESSMLGCLMQCKGLMELIAINIFFDTRLIGPKIYSALAMMALISTLLTVPAMTIISRVRRTATPCPTIDAAKQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H309</accession>
    <name>A0A2S9H309_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Type II secretion system protein K</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">S2091_0979</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 11">Cell inner membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the GSP K family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94358">
        <property type="protein sequence ID" value="PRC94358"/>
        <property type="gene ID" value="S2091_0979"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.40.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005628">
        <property type="entry name" value="GspK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038072">
        <property type="entry name" value="GspK_central_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38831">
        <property type="entry name" value="PTHR38831"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03934">
        <property type="entry name" value="T2SSK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002786">
        <property type="entry name" value="XcpX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158544">
        <property type="entry name" value="SSF158544"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="5 11" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10 11 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0653">Protein transport</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 11" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="26"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="180"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007246"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR002786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="PRC94358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="345" mass="37186" checksum="2114D3EEEB09A8C1" modified="2018-07-18" version="1">MQAAITKKSTLKASNRPTSTCRQRGVAIVTALLLTALAVTIVASVFWQQQVQVRAVENQRLQSQTQWVQRAALDWTRIILREDARTTAVDQLGEVWATPLPETPLDDYIEKDGSDSGNSGASGGTLSGKVIDAQSYYNLNNLAVGGVVDPQEIAVFKRLLGFLSINPNLAEATAKAIGATQAPTTAPSPPANTPDSTPASTPSAPSAGSTEQPALFIHTEDLITIPGYTVAVIDKLKNYVVILPRPTPVNVNTAGVEVLAAKANLSMEKATAMIASRSHAYFITTNDFQSRAQVDVPSGKFDIAVSTSFFMVFNKVQWDRASLNMQALIYRKSSGNTTVMWLREY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H342</accession>
    <name>A0A2S9H342_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Helix-turn-helix domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1023</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="SMR" id="A0A2S9H342"/>
    <dbReference type="EnsemblBacteria" id="PRC94402">
        <property type="protein sequence ID" value="PRC94402"/>
        <property type="gene ID" value="S2091_1023"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="26"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="99" mass="11559" checksum="E65B71C62831529B" modified="2018-07-18" version="1">MHFYIEINHNVLNTAHMDNQKLIQTLINRRKELRLTQIQLAELAQISRRAIIDFESGKTSISLRRLTRILYALELTLTIKPGGSRPSEAELRELFKDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3J5</accession>
    <name>A0A2S9H3J5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0540</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94537">
        <property type="protein sequence ID" value="PRC94537"/>
        <property type="gene ID" value="S2091_0540"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="60" mass="6157" checksum="9271C24544AC6216" modified="2018-07-18" version="1">MTSAISNVTKTAHTTPVTPPPKQVQNKAPQSNTQNTNKVTTPVPPTATSGNVGTKVNTTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3N8</accession>
    <name>A0A2S9H3N8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NADPH:quinone reductase and related Zn-dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0591</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94588">
        <property type="protein sequence ID" value="PRC94588"/>
        <property type="gene ID" value="S2091_0591"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PKS_ER" evidence="1">
        <location>
            <begin position="11"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="325" mass="34659" checksum="43A4244D14BB83CF" modified="2018-07-18" version="1">MMRAVVLCEPGGPKNLVLTELPMPQPRPGWVRIAIRAFGLNRSELHTRLGLSQGVTFPRVLGIEAVGVVDACPDGSVPLGQQVATMLGGMGRVFDGGYAEYVVVPCSQVIQFQSNLPWDVLGAVPETLQTAYGSLSVGLDLQAGQSLLIRGGTSALGLAAATLAKEIGATVIATTRQMDRINALLAHGVDYAIVDQGEINVEVRKIFPRGVDAALELVGTPTLSDTLRATRVHGTVCFTGMLSNQWTVKDFYPIDYIPRGVRLTSYAGGASDLPAAVLQKYLEQVAANMSTLGPIHTYSLDEIPRAHADMEHNRVFGKIVGVIKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3S0</accession>
    <name>A0A2S9H3S0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0519</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94516">
        <property type="protein sequence ID" value="PRC94516"/>
        <property type="gene ID" value="S2091_0519"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5016373326" evidence="1">
        <location>
            <begin position="27"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="199" mass="22002" checksum="DEA8F56B80BB12D8" modified="2018-07-18" version="1">MRVKFLNLFPFVFILPVMFLCTSAHADVTYGFVRIACIPENGMLDVEYRGLHDSVVDAAITGQVDKSGMLSKNGFHDPHGLHFQCKLNGADYVISAEQDTISNRMCGGSSDIYLSLARNGVALIRNVVFGNSCYGLPSLTQFTLGEGSSVRDNREAKFCFSLGEETTADKCEWIFGTDEFEKRLPIDQAAITHKFAPKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3T8</accession>
    <name>A0A2S9H3T8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Large extracellular alpha-helical protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_0641</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94638">
        <property type="protein sequence ID" value="PRC94638"/>
        <property type="gene ID" value="S2091_0641"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004866">
        <property type="term" value="F:endopeptidase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026284">
        <property type="entry name" value="A2-macglob_dom_prot_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011625">
        <property type="entry name" value="A2M_N_BRD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011626">
        <property type="entry name" value="Alpha-macroglobulin_TED"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021868">
        <property type="entry name" value="Alpha_2_Macroglob_MG3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041203">
        <property type="entry name" value="Bact_A2M_MG5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041462">
        <property type="entry name" value="Bact_A2M_MG6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041246">
        <property type="entry name" value="Bact_MG10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001599">
        <property type="entry name" value="Macroglobln_a2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002890">
        <property type="entry name" value="MG2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008930">
        <property type="entry name" value="Terpenoid_cyclase/PrenylTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00207">
        <property type="entry name" value="A2M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07703">
        <property type="entry name" value="A2M_BRD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17973">
        <property type="entry name" value="bMG10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11974">
        <property type="entry name" value="bMG3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17972">
        <property type="entry name" value="bMG5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17962">
        <property type="entry name" value="bMG6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01835">
        <property type="entry name" value="MG2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07678">
        <property type="entry name" value="TED_complement"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038980">
        <property type="entry name" value="A2M_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01360">
        <property type="entry name" value="A2M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01359">
        <property type="entry name" value="A2M_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48239">
        <property type="entry name" value="SSF48239"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="9"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="domain" description="A2M_N_2" evidence="5">
        <location>
            <begin position="809"/>
            <end position="953"/>
        </location>
    </feature>
    <feature type="domain" description="A2M" evidence="6">
        <location>
            <begin position="1014"/>
            <end position="1103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="94"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC94638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="1713" mass="189164" checksum="4166F1B9D243AD3E" modified="2018-07-18" version="1">MSKLSVTKFFIIFAVLASLIAGVWFFKNRHSAESAESDDPNQEFTAVNAADRSLDGVPALALTFSVPLDAGKTVDNYIQVFEMPATAEQLKRQAANLRQENDEEDYSGNGNDGDPAAITAVSTKDVDTDFKGGKLISGAWVVGDNPRILYFPHINPQTRYVVQVKVGLPSKNGKTLASETRYSILTAQVSPAYYFASNGMVLPAKQNGGLPIVTVNVPEVDVQFLKVKDDQLPRFLDRVIEGKKNLTVAKNASEDDADNNENYNNYDWRRSNLRGAVQNYQLDDLRKLTDSVYSGRFVTEQTKNKRSVTYLPVEDVKELKEPGVYVAVMSQPGRFTSDYQTTYFYVSDIGLHTRLYDKSADVFVSSLTDGKAVSGVELSWLDEQGKVLARADSDGDGHAVFAEQPKNAKVLLAKKGPQISMLALKEPALDLSEYTVTGAPYKPVRLFAYSGRNLYRPGESLDLSVVARDADGNGVPAQPIQAKLKSPDGREHFNATWRPDARYPGYFLQHLAIPADAATGSWVLELRADPADKIPATVFKFGVEEFLPERMKLDLNSKQATLKPDQEYTIAVSGNYLYGAPAAGNRLLGVVQFERNLNPLSKQFPGFEFGDVNENEKKTRKELEEQTLSDKGQAQVAVDLSPVAKRHSPFTVRTTLSLLESGGRPVVRSIEKTVWPAPVLVGVRPLFSGAYATENSPVEFEVIRANSDAKLQASTSMPVRLFREDRNYYWRFADHGGWQSGFTETEELVATSSVSIPADARGKLRLPVKYGRYRLEILDPATNQQLVYRFYAGWNAQSDEAQGNRPDRVALKLDKAAYKNGDTAQLTITPPHKGEALITVEGDHSLWVKRMSVAAEGSTVSIPIKEEWKRHDLYVSVIVLRPGNEGDKVTPARALGIVHLPLERGDRKLDVAIEAPAKIKPDTSVKIKVNVPNAKGQKAMVTLSAVDVGILNITKFATPDPHDFFFGRLRYGADLHDVYGRLIEKMAGQKGKLKYGGDTTPKPSKDLPKKVKLVDLFSGPVLLNEQGTAEITLNIPDFNGTLRLMAVVSGTDRYGSKEQEMVVAAPLVAEIATPRFLSLGDNALIALDLTNLSGNPQQFTLNLNGADGLKIGEGERSVSLKDQQKVTLRFPLEARGTLGLQNVNLKIAGKDINIERNFPLMVQAPTQQQQLKRRYVIKPGDTLEVKDAELSGMYPNSVLAHILVSNKAPIDVRAAVQGLLTYPYGCSEQTTSTAYPHVFIDEVMAKKFGLKPYTREQRVTMLDQAISRLATMQAPNGGYSLWGNVSDHEYWLSAYVSNFLVDAREQGFSVPDAMFNKSMDFLLRGLQEGVSRLPNTAAQIQAENNSVWAENRVKDNGRFNVLAFGGYVLSRTNKAPLATLRQLHDSRALAANGLALTQLGIALKQMGDGERSKVALQESLTKSRNAGYWWYDYGSTLRDAALAYGLLQQHQIKLDGSENLLAIVASEMDKYRYYSTQEKLALFQIGRNYDLQSGETWSASLALNGKDEDIGGNSQVFHEITARDLASGFKLKNNFKENIWLELALTGNPVKILPPKNDIIKLNRTLYAPDGSLIGNRPLTVGETVIMHLKVSANTSIGTGMVVDRIPAGMEIENTNIVQGEQMGVVRFDNINPAEAMQDQRIKHVEFRDDRFVVAARIDGQILNLFYRLRVVTPGKFVIPPLYVDDMYRPDVYGSIGGSESMTIVEARPPTAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H442</accession>
    <name>A0A2S9H442_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0743</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94740">
        <property type="protein sequence ID" value="PRC94740"/>
        <property type="gene ID" value="S2091_0743"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="41"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="224" mass="24764" checksum="765971C99A96C8B6" modified="2018-07-18" version="1">MDRIYKVIGISIALALVVGFALCGIIGIVAENPNNELEAMVIGFGLICVVTSVVCFFKVRNILTVVRAKDKPLSLFDREIRILDRIDNLVTKHGFSFQAWDDRYSKGVWAALGTSENQVDTVRELSSGGDNDMFYATDYVFSANWLPYVIGHTLGEAILALENRLAQLPSDQLNRESDWADLVRDAIESLRDATDGKSYYGDKLPDHLDALPKTFEAALSAKSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H486</accession>
    <name>A0A2S9H486_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Lipopolysaccharide-assembly, LptC-related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_0797</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94794">
        <property type="protein sequence ID" value="PRC94794"/>
        <property type="gene ID" value="S2091_0797"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015221">
        <property type="term" value="F:lipopolysaccharide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010664">
        <property type="entry name" value="LipoPS_assembly_LptC-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026265">
        <property type="entry name" value="LptC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06835">
        <property type="entry name" value="LptC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04409">
        <property type="entry name" value="LptC_YrbK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC94794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="206" mass="23335" checksum="4586D13995774121" modified="2018-07-18" version="1">MKISALFTPNNLRLWLLVMFVGLASLASYWVLEIIRSNDKNGAQAVRTRPDYYVDNFNFVKMLPNGQSKYRIVGTELIHYPDDDHADVTLPVMTNLDATQPPLTVRSERGVIKNIANQSENEVHLYEKVVVNRHKTDISAHLQLDTEYLLAYPDKNTMQTDLPVRILAGDTITTGVGLRANNATQQMQILSNVYSIVPPRTNQKRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H496</accession>
    <name>A0A2S9H496_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">UvrABC system protein A</fullName>
            <shortName evidence="14">UvrA protein</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Excinuclease ABC subunit A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">uvrA</name>
        <name evidence="18" type="ORF">S2091_0803</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.</text>
    </comment>
    <comment type="subunit">
        <text evidence="14">Forms a heterotetramer with UvrB during the search for lesions.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="14">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="14">Belongs to the ABC transporter superfamily. UvrA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94800">
        <property type="protein sequence ID" value="PRC94800"/>
        <property type="gene ID" value="S2091_0803"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009380">
        <property type="term" value="C:excinuclease repair complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009381">
        <property type="term" value="F:excinuclease ABC activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009432">
        <property type="term" value="P:SOS response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00205">
        <property type="entry name" value="UvrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004602">
        <property type="entry name" value="UvrA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041552">
        <property type="entry name" value="UvrA_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041102">
        <property type="entry name" value="UvrA_inter"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17755">
        <property type="entry name" value="UvrA_DNA-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17760">
        <property type="entry name" value="UvrA_inter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00630">
        <property type="entry name" value="uvra"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 14 15" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 14" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 14" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6 14" id="KW-0228">DNA excision</keyword>
    <keyword evidence="13 14" id="KW-0234">DNA repair</keyword>
    <keyword evidence="12 14" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="10 14" id="KW-0267">Excision nuclease</keyword>
    <keyword evidence="2 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 14 15" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 14" id="KW-0677">Repeat</keyword>
    <keyword evidence="14" id="KW-0742">SOS response</keyword>
    <keyword evidence="11" id="KW-1278">Translocase</keyword>
    <keyword evidence="8 14" id="KW-0862">Zinc</keyword>
    <keyword evidence="7 14" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="ABC transporter" evidence="17">
        <location>
            <begin position="657"/>
            <end position="986"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C4-type" evidence="14">
        <location>
            <begin position="299"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C4-type" evidence="14">
        <location>
            <begin position="789"/>
            <end position="815"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <begin position="73"/>
            <end position="80"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14 15">
        <location>
            <begin position="690"/>
            <end position="697"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="PRC94800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="990" mass="108748" checksum="A9628A4CE905E154" modified="2018-07-18" version="1">MSKMSKNSTKDTGIVSSAKAKTPAKLKNPPKTAPTTLATHDSRDQIRVRGARTHNLKNISLDLPRNQLVVITGLSGSGKSSLAFDTLYAEGQRRYVESLSAYARQFLQLMEKPDVDLIEGLSPAISIEQKATSHNPRSTVGTVTEIHDYLRLLYARVGTPYCPDHPENPLAAQSVSQMVDLVLAMPEDTRLMILAPVVANRKGEHVDFFEQMQAQGFVRFRLQSGTAAPKIVEIDDLPKLKKTEKHTISVVVDRIKVKADIKQRLAESFETALRLAEGRAIAVEMDSDKEHLYSNKFACPTCGYSLQELEPRLFSFNNPMGACPECDGLGHIEFFDPKRIVAFPNLSLASGAVKGWDRRNQFYFQMLSNLAAFYEFDIDTPFEQLPEAAQQVILYGSGKQHIPFTYINEKGKTVIREHSFEGVVTNLQRRYRETDSMAVKEELAKFINEKECPACHGARLRVEARFVKVGNGAQESSIYEVSALPLRKALAFFETLELTGAKKEIADRIIKEIASRLKFLNNVGLDYLSLDRSSDTLSGGEAQRIRLASQIGSGLTGVMYVLDEPSIGLHQRDNDRLIGTLQHLRDIGNSVLVVEHDEDAIRCADYVIDMGLGAGVHGGEVIAAGTLEDILSNPRSLTAQYLNGTKKIAVPKTRTQFDAEKLFTISGATGNNLKGVTLNLPVGLLTCVTGVSGSGKSTLINDTLYLATAHHIYGSHAEPAAHESISGFNHFDKVISVDQGPIGRTPRSNPATYTGLFTPIRDLFSTVPSAKERGYSAGRFSFNVKGGRCEACQGDGVIKVEMHFLPDVYVPCDVCHGKRYNRETLEVHYKGKNIQEVLGMTVEEAHQFFSVVPLIARKLQTLLDVGLGYIRLGQSATTLSGGEAQRVKLSLELSKRDTGRTLYILDEPTTGLHFHDIDLLLKVIHRLRDQGNTVVIIEHNLDVIKTADWLIDLGPEGGAGGGQIIATGTPEQVANNPASVTGKYLLPLLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4C6</accession>
    <name>A0A2S9H4C6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Negative regulator of beta-lactamase expression</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0030</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94835">
        <property type="protein sequence ID" value="PRC94835"/>
        <property type="gene ID" value="S2091_0030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008745">
        <property type="term" value="F:N-acetylmuramoyl-L-alanine amidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009253">
        <property type="term" value="P:peptidoglycan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06583">
        <property type="entry name" value="PGRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.101.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.80.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036505">
        <property type="entry name" value="Amidase/PGRP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002502">
        <property type="entry name" value="Amidase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002477">
        <property type="entry name" value="Peptidoglycan-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036365">
        <property type="entry name" value="PGBD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036366">
        <property type="entry name" value="PGBDSf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01510">
        <property type="entry name" value="Amidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01471">
        <property type="entry name" value="PG_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00644">
        <property type="entry name" value="Ami_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47090">
        <property type="entry name" value="SSF47090"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55846">
        <property type="entry name" value="SSF55846"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetylmuramoyl-L-alanine amidase" evidence="1">
        <location>
            <begin position="41"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="279" mass="31047" checksum="48E3DAEBED8CC41C" modified="2018-07-18" version="1">MEKTLRALLIISLFILCVGCATTASVIDKPVGSASAAPVIDKTYRAVSQDSRVRFLIIHYTAIDLPTSIDVLTNRDVSAHYLVTDEAEPRILSLVEENARAYHAGLSTWKNFSNLNSASIGIEIVNPGWVDTPDERVYAAFPEQQIDTLIPLIQDIVKRHDIAPGNILGHNDIAPQRKQDPGPLFPWVRLADLGLINWPDAQQVSFKKIDYDAQLPDLIWFQNKLIEHGFQLTPSGQLDQATRNVVSTFQMKYRPANYDGVPDAETAALLDVITSKKNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4I3</accession>
    <name>A0A2S9H4I3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putative Zn-dependent protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_0048</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase U62 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94853">
        <property type="protein sequence ID" value="PRC94853"/>
        <property type="gene ID" value="S2091_0048"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045569">
        <property type="entry name" value="Metalloprtase-TldD/E_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045570">
        <property type="entry name" value="Metalloprtase-TldD/E_cen_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002510">
        <property type="entry name" value="Metalloprtase-TldD/E_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025502">
        <property type="entry name" value="TldD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035068">
        <property type="entry name" value="TldD/PmbA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036059">
        <property type="entry name" value="TldD/PmbA_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01523">
        <property type="entry name" value="PmbA_TldD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19289">
        <property type="entry name" value="PmbA_TldD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19290">
        <property type="entry name" value="PmbA_TldD_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004919">
        <property type="entry name" value="TldD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111283">
        <property type="entry name" value="SSF111283"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PmbA_TldD" evidence="3">
        <location>
            <begin position="43"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="domain" description="PmbA_TldD_M" evidence="5">
        <location>
            <begin position="134"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="domain" description="PmbA_TldD_C" evidence="4">
        <location>
            <begin position="250"/>
            <end position="483"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01523"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF19289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF19290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC94853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="485" mass="51619" checksum="74A1493BA2AEDAEF" modified="2018-07-18" version="1">MDIMNSSNNLSLARSILLTPFGLDDVALTSTLASMFSHKVDYADLYFQFTKSESWSLEEGIVKTGSFNIDQGVGVRAVSGDKTAFSYSDEISLEALKEAVAATRTIARYGQGKVKVATSMHGHVGHSLYFPHDPLSSLDSTAKVQLLEKIEKMARAKDPRVKQVMAGLAGEYDVVLVARSDGVIAGDVRPLVRLSLTVIAEQNGRREMGSAGGGGRYDYAYFSDEMLEKYVDEAVAGALINLEARPAPAGPMTVVLGPGWPGVLLHEAIGHGLEGDFNRKGSSAFSGRLGERVAAAGVTVVDDGTLRDRRGSLNMDDEGNPTQCTTLIENGILKGYIQDTMNARLMKMPVTGNARRESFAHLPMPRMTNTYMLAGDKDPAEILASVKNGLYAVNFGGGQVDITNGKFVFSASEAYMIEDGKVTYPVKGATLIGNGPDVLHRVSMIGNDLRLDSGVGVCGKEGQSVPVGVGQPTLRLDGITVGGTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4I6</accession>
    <name>A0A2S9H4I6_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">ATP-binding protein Uup</fullName>
            <ecNumber evidence="8">3.6.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">uup</name>
        <name evidence="11" type="ORF">S2091_0095</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>ATP + H2O = ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="8">Associates with ribosomes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.-" evidence="8"/>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94900">
        <property type="protein sequence ID" value="PRC94900"/>
        <property type="gene ID" value="S2091_0095"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00848">
        <property type="entry name" value="Uup"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032524">
        <property type="entry name" value="ABC_tran_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032781">
        <property type="entry name" value="ABC_tran_Xtn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043686">
        <property type="entry name" value="Uup"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037118">
        <property type="entry name" value="Val-tRNA_synth_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16326">
        <property type="entry name" value="ABC_tran_CTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12848">
        <property type="entry name" value="ABC_tran_Xtn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="2 8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0227">DNA damage</keyword>
    <keyword evidence="8" id="KW-0234">DNA repair</keyword>
    <keyword evidence="8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 8 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-1278">Translocase</keyword>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="7"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="323"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8 9">
        <location>
            <begin position="39"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8 9">
        <location>
            <begin position="355"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC94900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="635" mass="70670" checksum="F4B5F53CD03F1326" modified="2018-07-18" version="1">MNVMAVISLSNAQLAFGHVALLDHTEFSIETGERVGLIGRNGTGKSSLLKVIAGTSKLDDGLLVMQQNLRIAYVEQEPLFDPTKTVFDSVAEGLGELPALLKEYETISGQFGGDNDDALMERMHDIQLQLDAADAWGLSSKVEATLDRLNLQKDALIGSLSGGMKKRVALAVALVSAPDVLLLDEPTNHLDYSSILWLEGLLRDFKGSVLLITHDRSFLDNVCTRIIELDRGRILSFPGNFTTYQTRKAELLENEVVENAKFDKFLAQEEIWIRKGVQARRTRDEGRVRRLEDLRKQRTVRRDQQGQVNLNVSAGERSGKIVAELENVCKNYGSKCIINNFSGTILRGDKVGLIGANGAGKTTLLKMILGEETPDSGTIKQGSKLQVAYFDQMRAQLNEEASLAETIAPGSDWVEINGQKKHVMTYLNDFLFAAERARSPVKSLSGGERNRLLLARLFAKPANALVLDEPTNDLDIDTLELLEELLENYTGTVFLVSHDRAFLDNVVTQVIVSEGEGQWNEYIGGFSDWERYANSVKENAKTASKSAAKVVTKAEPASKAKKLSYKEQRELEDLPKQIAKLEAEQQVITVRLQDTNLYKTQPDEVNKLNQRYAEIDELLLVSLEQWEAIEARSKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4P4</accession>
    <name>A0A2S9H4P4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC-type branched-chain amino acid transport systems periplasmic component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_0132</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the leucine-binding protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94937">
        <property type="protein sequence ID" value="PRC94937"/>
        <property type="gene ID" value="S2091_0132"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028081">
        <property type="entry name" value="Leu-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000709">
        <property type="entry name" value="Leu_Ile_Val-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13458">
        <property type="entry name" value="Peripla_BP_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00337">
        <property type="entry name" value="LEUILEVALBP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015765841" evidence="3">
        <location>
            <begin position="23"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="domain" description="Peripla_BP_6" evidence="4">
        <location>
            <begin position="25"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC94937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="385" mass="41404" checksum="2082BFC7C6278E71" modified="2018-07-18" version="1">MNTTLKLLVVSMALGFSAASMAADPIKIGVAGPFTGGSAPMGMSMRDGVKLAVAEINAKGGVLGRQLQLVERDDEAKNERGVQIAQEMINKEKVVATVGFINTGVALAAQRFYQEAKIPVMDNVATGSIVTKQFPDQPENYIFRNAASDTIQSAMIVQEAVDRRKFKKVAILADSTNYGQLGREDLEKALDKKGLKAVAVEKYNLKDVDMTAQLLKAKQAGAEVVLTYGIGPELAQIANGMEKLGWKVPLIGSWTLSMANFIDNAGKNGDGTRMPQTFIEDGTTPKRKAFIDAYVKTYHPPNGRMPSPVSAAQGYDSIYLLVAAMKQAGTTDGPKVRAALENLNDKIDGVVTTYSKPFSKDNHEAINADLTVFGEVRDGRVVLAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H505</accession>
    <name>A0A2S9H505_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="12">D-alanyl-D-alanine carboxypeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">S2091_0259</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the peptidase S11 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95064">
        <property type="protein sequence ID" value="PRC95064"/>
        <property type="gene ID" value="S2091_0259"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009002">
        <property type="term" value="F:serine-type D-Ala-D-Ala carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018044">
        <property type="entry name" value="Peptidase_S11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001967">
        <property type="entry name" value="Peptidase_S11_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00768">
        <property type="entry name" value="Peptidase_S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00725">
        <property type="entry name" value="DADACBPTASE1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="3" id="KW-0133">Cell shape</keyword>
    <keyword evidence="5" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="12" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015443901" evidence="10">
        <location>
            <begin position="23"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S11" evidence="11">
        <location>
            <begin position="100"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="25"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="25"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="54"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-ester intermediate" evidence="6">
        <location>
            <position position="134"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="137"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="191"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="296"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR618044-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR618044-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PRC95064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="355" mass="38134" checksum="44C8C6E47E51C2F6" modified="2018-07-18" version="1">MLKFSTAFAIALLFSSTTIVEAKTQTTDQTTAASTAAATPSTGKAATKKATVTKKATTTKKTAKKATKAKSKKTKAKSSKVAVVPEKQSFGDLEGLQRTQDPLDLKSSAALVIDQASSQVLFEKNSSVSLPIASITKLMTSLVVLEANQDMDEVLLVTNEDIDTEKGSSSRLKIGSKLKRSDMLHIALMSSENRAASSLGRNYPGGLQACVAAMNAKAKLLGMTETHYVDSTGLSSQNVASAQDLAKLVNEAYHQTLIRQYSTDTKYAVSPGGRTLEYTSSNRLTSNADWEIGLQKTGYITEAGRCLVMQAMIEGRAVVMVFLDSKGKYSRFADAGRIRKWLETIKPPVPKTVVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H516</accession>
    <name>A0A2S9H516_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_0161</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94966">
        <property type="protein sequence ID" value="PRC94966"/>
        <property type="gene ID" value="S2091_0161"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05926">
        <property type="entry name" value="FACL_fum10p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045310">
        <property type="entry name" value="Pcs60-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-binding" evidence="2">
        <location>
            <begin position="17"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding_C" evidence="3">
        <location>
            <begin position="418"/>
            <end position="493"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC94966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="506" mass="53985" checksum="B107FE5CB14CCE98" modified="2018-07-18" version="1">MQRPTTILELLAIGASDAIAISAPGVTPLTYGQLRLTSAQTEQSLRSIGIGAQDRVALVLPNGPEMAVAFTCIAAHAAAAPLNPAYRADEFEFYLSDLNAKAILVEHGSQSPAIAIAQKLNLQILELHPSGHGAGSFTLTAQQPVMNTASADMPTSNDLALILHTSGTTSRPKIVPLTQANVCASACNVRDNLHLSASDCGLAIMPLFHIHGLIAGLLAPLAAGGQIFCTPGFNALRFFNWMNEAKPSWYTAVPTMHQTIVARAESNREIIQANPLRFIRSSSSSMPPQVIHALEQVFNAPLIESYGMTEAAHQMASNPLPPAKRIPGSVGIAAGPEIAIMDTDGNLLENGATGEIVIRGVNVTAGYENNPKANAEAYTNGWFRTGDQGVLDQDNYLSITGRLKEIINRGGEKISPREVDEILMDHPAVAQVVTFGMPHEKLGEEVAAAVVLREGQQVSEKELREFVAIRLSDYKVPRKILFLEEIPKGATGKLQRIGLAAKLGLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5A8</accession>
    <name>A0A2S9H5A8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">TonB-Xanth-Caul: TonB-dependent receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_0308</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95113">
        <property type="protein sequence ID" value="PRC95113"/>
        <property type="gene ID" value="S2091_0308"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041700">
        <property type="entry name" value="OMP_b-brl_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010104">
        <property type="entry name" value="TonB_rcpt_bac"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14905">
        <property type="entry name" value="OMP_b-brl_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01782">
        <property type="entry name" value="TonB-Xanth-Caul"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0675">Receptor</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015566250" evidence="2">
        <location>
            <begin position="43"/>
            <end position="898"/>
        </location>
    </feature>
    <feature type="domain" description="Plug" evidence="3">
        <location>
            <begin position="86"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="domain" description="OMP_b-brl_3" evidence="4">
        <location>
            <begin position="567"/>
            <end position="898"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF14905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC95113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="898" mass="97207" checksum="181122D483625D69" modified="2018-07-18" version="1">MKPIDMQRIQPVSFKLTPLAKSILLLCSALCANTALVQPAWAAADETPLVAEASPADAGDTKPVSAIEEITILGQRATAYNAIKAQKEAPNLINVLTSDEIRKLPDVNVAEAVARLPGISLETDTGEGRFINIRGLDSDLNSTTFAGLRLPPSNPASPQNGGRAVALDAIPNGLVGSITVTKSNLPEQDAEALGGTIEITPKTAPADGKPFFDGHIGSGYEGLRGTAITDVSATVGGRFGGSGEHTNGISSYSDHPFSAVFTAAYYHDKRGIDDVEQSYIDDGVHPSNSLADIDMRRYQYDRQRHGVGLDLGAQPDANSTYYIRAFDAGYTEAKQNNHLQITMDGNPVTAPGGGFTDGVSANGFDKFLTDEKEKIDNQVFMVGGQNKFGGNVLDYRLGYTKGSYNQFYDYKADFNYTPSAGSITYNNTGAGNTSLFNVSGANYLNPGNYTLGSFKNQTEDITDHEWSFASNLKMPVSWGSFDDENIKFGLDARVRTRNAEEQPYSYKGIPNLPLTSVATGGDTTFYNGIYQIGPLIPAGELNTQLASYQIIKASDMLNAQLAYQHDTENVNSLYWQYQMTAGKLGVIAGVRVENTNAQYDAISQGVDAGGNNVVEPSSMARHYTNAFPSAQARYELDPATLLRASFSSTIARPGFNQINPSVQVSSADNTVSVGNPNLKPTTANSFDLSYEKYLPHSGIFSVGLFDKEIKNYIVATTYNQMFQNSGLYAGLAGEASVTSFTNTNSGYARGLEFNYQQKFKELPDFWSGFGVNLNYTFVDSGTDIHPGFTSMLPSTSRNNANAMLFYERDGLDLRLGVNYVSADLWAIGGNATTPDTFSDARLQVDFGGSYVINEKISLYFSAKNISNTPLKFYEGSPDRPIQREFYGPTFLAGLNFSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5B3</accession>
    <name>A0A2S9H5B3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">GGDEF: diguanylate cyclase (GGDEF) domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_0374</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95179">
        <property type="protein sequence ID" value="PRC95179"/>
        <property type="gene ID" value="S2091_0374"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01948">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001633">
        <property type="entry name" value="EAL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035919">
        <property type="entry name" value="EAL_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00563">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13185">
        <property type="entry name" value="GAF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00052">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141868">
        <property type="entry name" value="SSF141868"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50883">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="1"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="6">
        <location>
            <begin position="335"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="domain" description="EAL" evidence="5">
        <location>
            <begin position="475"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="741"/>
            <end position="856"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="3">
        <location>
            <position position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC95179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="863" mass="95599" checksum="CD70A52AF7685CE4" modified="2018-07-18" version="1">MATLKQILGNDYSLVFARNGTEGLAAVKKHLPALILLDVQMPDMDGYTVCKMIKADPLTENTPVIFISALSDVGDETTGFLCGGVDYIIKPVSPAIVRARVATHLSLVRATTLELYVKQLEIERTKTARLSRILAVLSGTNSAIVRIRESHALMEEACRIAVDHGGFGIAWIGLAQDNAALSIAASQGIESDQLIATLQPSVGKSPDSIEISSQVLKTGQTCIFNDVRSATSTSATCRDALSRGYLSLIALPLTGNNKIAGVVVLYARELNCFDEEEIKLLSELAGDISFALQAIENGKRASFLAYYDELTGLPNTTLFLDRLDQLIQSAWFEKSKVFVIILNLNRFKELNDTYGRHIGDKVLITVAQYLDEGSLHSCSAARIGADNFALLGVEANSGDVTKLCDQILIMLAKPFNIDGKSFTVSPRLGIAIYPTDAENTEALFKNAETALKQAKFTKSLYSYYSPEHNAKIAEKIELENMLKLALDNNQFVMYYQPKVDLDTGKIVGAEALIRWKHPERGMVPPVEFIPLAEETGLIVPIGTWVIQAVCAQQATWKRDRIPIVPVALNLSALQFRQGNVLQIVRDALSEYKLEPNELELELTESLVMQNLQEAETIMRSFHQHGLHLSLDDFGTGYSSLAYLKRFPFDTVKIDRAFVTDITRNPEDAAIALAIIAMAHNLHMNVVAEGVETEAQLKFLRARHCDQIQGYFFSPPVTADEFGMMLHTRKHIEPSVDTQDQTLLLVDSDSFILSALTRTLRGQGYRILTALGGREALEVLATNPVQVILCEQLMSEMTGAEFFSITAKLYPDTMRIILTGYTELQSVLEAINSGEIYRFLTKPWDDELIRQNILDAFRRYRPMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5D0</accession>
    <name>A0A2S9H5D0_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">Cell division protein FtsA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ftsA</name>
        <name evidence="9" type="ORF">S2091_0395</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 7">Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Self-interacts. Interacts with FtsZ.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Peripheral membrane protein</topology>
            <orientation evidence="6">Cytoplasmic side</orientation>
        </subcellularLocation>
        <text evidence="6">Localizes to the Z ring in an FtsZ-dependent manner. Targeted to the membrane through a conserved C-terminal amphipathic helix.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6 7">Belongs to the FtsA/MreB family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the heat shock protein 70 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95200">
        <property type="protein sequence ID" value="PRC95200"/>
        <property type="gene ID" value="S2091_0395"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032153">
        <property type="term" value="C:cell division site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009898">
        <property type="term" value="C:cytoplasmic side of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043093">
        <property type="term" value="P:FtsZ-dependent cytokinesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02033">
        <property type="entry name" value="FtsA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020823">
        <property type="entry name" value="Cell_div_FtsA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018181">
        <property type="entry name" value="Heat_shock_70_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003494">
        <property type="entry name" value="SHS2_FtsA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02491">
        <property type="entry name" value="SHS2_FTSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003101">
        <property type="entry name" value="FtsA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00842">
        <property type="entry name" value="FtsA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01174">
        <property type="entry name" value="ftsA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01036">
        <property type="entry name" value="HSP70_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3 6 7" id="KW-0132">Cell division</keyword>
    <keyword evidence="2 6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FtsA" evidence="8">
        <location>
            <begin position="9"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR003101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC95200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="410" mass="44459" checksum="40C4D0B56AB052D0" modified="2018-07-18" version="1">MTKDAKNLIVGLDIGTSKVVAVVAEVMPDGRHEVIGLGQHESKGLKKGVVVNIEATVESIQRALEEAELMADCKIRNVYTGIAGSHIRSINSRGMVAIKDKEVTAADVSRVIETAKAINISTDQQLLHTVPQEFIVDNQDDVREPIGMSGIRLEVKVHIVTGSVSAVQNIVKCVRRCGLEVADLILQPMASADAVLTLDEKELGVVLIDIGGGTTDVAVFSEGAIRHTVTIPIAGDQITNDIAMAIRTPTAEAEEIKIRFGVAKQTLADPAQTLEVPGLGDREPRSMSRQALAAVIEPRVEELFAFVHQVIRESGYEDVLSSGVVLTGGSSMMPGMVEMAEDIFLKPTRIGMPEYQGQLSDVVRSPRYSTVLGLLLEAKKQYLRGHLVSRQEGSAKAVWQRMKEWFFGTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5D8</accession>
    <name>A0A2S9H5D8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Outer membrane efflux protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0281</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95086">
        <property type="protein sequence ID" value="PRC95086"/>
        <property type="gene ID" value="S2091_0281"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015562">
        <property type="term" value="F:efflux transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003423">
        <property type="entry name" value="OMP_efflux"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02321">
        <property type="entry name" value="OEP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015542933" evidence="2">
        <location>
            <begin position="31"/>
            <end position="450"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC95086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="450" mass="49152" checksum="B9859F6E7574428A" modified="2018-07-18" version="1">MKKINSSARRYRRLWAALAVLPMLNSPAVAETAPPAAFTGTDILFKHYLDAVEQHNSDLAAERENIVSAEAGVSIAGVRPDPELTFGIDSYELYKPQKPNASTATTASIAFTIETAGKRGKRINAARSNVKLAQVTVEGFKHELYLQATEAFTEACRSQQALLRQEATLKSLSDVVKINAIRRKAGDVSGLELSQSRVERDQFEAEVISARADAEAALLNLSIPLGKHLSAQFGDAPLSCEFSRFETTDEPSQLIRQALTARDEMLIAQATLDHARDNATLERANRYIDPVINLGITNTPPVHPIFNDEGEASNDVAGRSRTLGLTVTIPIPFSHMQRGELAQAESTVTQAMLGLRSAHLKTEIAVSSAFAQFQAKRENVRRYQESVLLDSDQVLEGIRLSYRKGAASLLELLDAQRSADDAYLSFLQAQADLTIATVQLQLAIGQRPTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5I3</accession>
    <name>A0A2S9H5I3_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">YCII domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0445</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the YciI family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95250">
        <property type="protein sequence ID" value="PRC95250"/>
        <property type="gene ID" value="S2091_0445"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005545">
        <property type="entry name" value="YCII"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03795">
        <property type="entry name" value="YCII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YCII" evidence="2">
        <location>
            <begin position="4"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC95250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="84" mass="9396" checksum="E459A01F48AB514C" modified="2018-07-18" version="1">MQRYLVMTIRTPQFQTSVIDAHYAFLDRLRQQGKLELAGPFSDKSGGAYLIKAANLDEARAVAFSDPVHTTNSSDVTVYEWNAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5J9</accession>
    <name>A0A2S9H5J9_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 11">UDP-N-acetylmuramate--L-alanine ligase</fullName>
            <ecNumber evidence="4 11">6.3.2.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">UDP-N-acetylmuramoyl-L-alanine synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">murC</name>
        <name evidence="15" type="ORF">S2091_0398</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Cell wall formation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>ATP + L-alanine + UDP-N-acetyl-alpha-D-muramate = ADP + H(+) + phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanine</text>
            <dbReference type="Rhea" id="RHEA:23372"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="ChEBI" id="CHEBI:70757"/>
            <dbReference type="ChEBI" id="CHEBI:83898"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.8"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 11">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the MurCDEF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.8" evidence="4 11"/>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95203">
        <property type="protein sequence ID" value="PRC95203"/>
        <property type="gene ID" value="S2091_0398"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008763">
        <property type="term" value="F:UDP-N-acetylmuramate-L-alanine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00046">
        <property type="entry name" value="MurC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036565">
        <property type="entry name" value="Mur-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004101">
        <property type="entry name" value="Mur_ligase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036615">
        <property type="entry name" value="Mur_ligase_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013221">
        <property type="entry name" value="Mur_ligase_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000713">
        <property type="entry name" value="Mur_ligase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005758">
        <property type="entry name" value="UDP-N-AcMur_Ala_ligase_MurC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01225">
        <property type="entry name" value="Mur_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02875">
        <property type="entry name" value="Mur_ligase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08245">
        <property type="entry name" value="Mur_ligase_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53244">
        <property type="entry name" value="SSF53244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53623">
        <property type="entry name" value="SSF53623"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01082">
        <property type="entry name" value="murC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 11" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="6 11" id="KW-0132">Cell division</keyword>
    <keyword evidence="7 11" id="KW-0133">Cell shape</keyword>
    <keyword evidence="10 11" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="5 11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11 15" id="KW-0436">Ligase</keyword>
    <keyword evidence="11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8 11" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mur_ligase" evidence="12">
        <location>
            <begin position="7"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="domain" description="Mur_ligase_M" evidence="14">
        <location>
            <begin position="110"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="domain" description="Mur_ligase_C" evidence="13">
        <location>
            <begin position="312"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="112"/>
            <end position="118"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF08245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="PRC95203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="487" mass="51480" checksum="056D1209E21C720F" modified="2018-07-18" version="1">MKHKVKHLHFVGIGGSGMSGIAEVLMNLGYAVSGSDLASNAASQRLAKLGAKIMLGHDAKNIIGADAVVTSTAVKSDNAEVLAARAAHVPIVPRAMMLAELMRLKRGIAIAGTHGKTTTTSLVASVLAQGGLDPTFVIGGLLNSAGANAKLGSGDFIVAEADESDASFLNLSPVISVITNIDADHMETYGHDFAKLKQAFIEFTQRLPFYGVAVLCLDDANVREIMPFISKPISTYGFHAEADVRAVNAVAVAGKMQFTVIQKDYPDMQISLNQPGMHNVQNACAAIAIARELSVSNEDIQTALNDFNGVGRRFTRYGEIALPAQAGMPVGRFALVDDYGHHPVEMAATLSAARGAYPGRRLVLAFQPHRYTRTRDLFEDFVKVMSSADVVVLAEVYAAGEPPIVAADGRSLSRALRVLGQVDPVFVENITDFASTLLGILKDGDVVITMGAGSINGVPAQLVNSQDQIAIQIEANSAATKIEQASE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5N5</accession>
    <name>A0A2S9H5N5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">CbiX</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0446</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95251">
        <property type="protein sequence ID" value="PRC95251"/>
        <property type="gene ID" value="S2091_0446"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002762">
        <property type="entry name" value="CbiX-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01903">
        <property type="entry name" value="CbiX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC95251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="132" mass="14496" checksum="6C4322F57A61A740" modified="2018-07-18" version="1">MSAPQNQHQALILFAHGARDPRWAEPLARLQQLIAASVSSSVHIHQAFLELMSPTLPELVAQLAAQHCQAITVVPIFLGQGGHVRRDLPQLMTQLEAQYPQIQFNLATAIGENERVLMAIAEVCVANLFKSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5S3</accession>
    <name>A0A2S9H5S3_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Leucyl/phenylalanyl-tRNA--protein transferase</fullName>
            <ecNumber evidence="4">2.3.2.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">L/F-transferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Leucyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Phenyalanyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">aat</name>
        <name evidence="5" type="ORF">S2091_0486</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>L-leucyl-tRNA(Leu) + N-terminal L-arginyl-[protein] = H(+) + N-terminal L-leucyl-L-arginyl-[protein] + tRNA(Leu)</text>
            <dbReference type="Rhea" id="RHEA:50416"/>
            <dbReference type="Rhea" id="RHEA-COMP:9613"/>
            <dbReference type="Rhea" id="RHEA-COMP:9622"/>
            <dbReference type="Rhea" id="RHEA-COMP:12672"/>
            <dbReference type="Rhea" id="RHEA-COMP:12673"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:64719"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78494"/>
            <dbReference type="ChEBI" id="CHEBI:133044"/>
            <dbReference type="EC" id="2.3.2.6"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>L-leucyl-tRNA(Leu) + N-terminal L-lysyl-[protein] = H(+) + N-terminal L-leucyl-L-lysyl-[protein] + tRNA(Leu)</text>
            <dbReference type="Rhea" id="RHEA:12340"/>
            <dbReference type="Rhea" id="RHEA-COMP:9613"/>
            <dbReference type="Rhea" id="RHEA-COMP:9622"/>
            <dbReference type="Rhea" id="RHEA-COMP:12670"/>
            <dbReference type="Rhea" id="RHEA-COMP:12671"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:65249"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78494"/>
            <dbReference type="ChEBI" id="CHEBI:133043"/>
            <dbReference type="EC" id="2.3.2.6"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>an N-terminal L-alpha-aminoacyl-[protein] + L-phenylalanyl-tRNA(Phe) = an N-terminal L-phenylalanyl-L-alpha-aminoacyl-[protein] + tRNA(Phe)</text>
            <dbReference type="Rhea" id="RHEA:43632"/>
            <dbReference type="Rhea" id="RHEA-COMP:9668"/>
            <dbReference type="Rhea" id="RHEA-COMP:9699"/>
            <dbReference type="Rhea" id="RHEA-COMP:10636"/>
            <dbReference type="Rhea" id="RHEA-COMP:10637"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78531"/>
            <dbReference type="ChEBI" id="CHEBI:78597"/>
            <dbReference type="ChEBI" id="CHEBI:83561"/>
            <dbReference type="EC" id="2.3.2.6"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the L/F-transferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.6" evidence="4"/>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95291">
        <property type="protein sequence ID" value="PRC95291"/>
        <property type="gene ID" value="S2091_0486"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008914">
        <property type="term" value="F:leucyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030163">
        <property type="term" value="P:protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3550">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00688">
        <property type="entry name" value="Leu_Phe_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004616">
        <property type="entry name" value="Leu/Phe-tRNA_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042203">
        <property type="entry name" value="Leu/Phe-tRNA_Trfase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042221">
        <property type="entry name" value="Leu/Phe-tRNA_Trfase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30098">
        <property type="entry name" value="PTHR30098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03588">
        <property type="entry name" value="Leu_Phe_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00667">
        <property type="entry name" value="aat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="1 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4 5" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC95291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="238" mass="26822" checksum="50FFD92AC8F7510F" modified="2018-07-18" version="1">MIPWLEADTPFPSVETALTEQQGAAGLLAAGADLSAQRLLDAYRQGIFPWFSEGQPILWWSTDPRMVLYTEHFKLSKSLKKTLRKLQNNPLVEFKFDSAFESVMRACAAPRRDGTGTWISEQMISAYTELHRMGYAHSSEVWINGELVGGAYGLCIGRMFYGESMFSRVSDASKMALAQLVFFLKSQQVQMIDCQQETEHLASLGAAPIARQEFTNWIQQAVLQPSIREWKLSEKIGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSF5</accession>
    <name>A0A2S9GSF5_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="11 12">ATP synthase subunit a</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">ATP synthase F0 sector subunit a</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">F-ATPase subunit 6</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">atpB</name>
        <name evidence="13" type="ORF">S2091_4648</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11 12">Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11 12">Cell membrane</location>
            <topology evidence="11 12">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11 12">Belongs to the ATPase A chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000041">
        <property type="protein sequence ID" value="PRC90640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90640">
        <property type="protein sequence ID" value="PRC90640"/>
        <property type="gene ID" value="S2091_4648"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045263">
        <property type="term" value="C:proton-transporting ATP synthase complex, coupling factor F(o)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01393">
        <property type="entry name" value="ATP_synth_a_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045082">
        <property type="entry name" value="ATP_syn_F0_a_bact/chloroplast"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000568">
        <property type="entry name" value="ATP_synth_F0_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023011">
        <property type="entry name" value="ATP_synth_F0_asu_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035908">
        <property type="entry name" value="F0_ATP_A_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42823">
        <property type="entry name" value="PTHR42823"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00119">
        <property type="entry name" value="ATP-synt_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81336">
        <property type="entry name" value="SSF81336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01131">
        <property type="entry name" value="ATP_synt_6_or_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00449">
        <property type="entry name" value="ATPASE_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 11" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="11" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 11 12" id="KW-0138">CF(0)</keyword>
    <keyword evidence="6 11 12" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="8 11 12" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11 12" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="40"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="94"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="144"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="175"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="216"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="242"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PRC90640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="273" mass="30002" checksum="6FE720BC2DA6D747" modified="2018-07-18" version="1">MSAPELAPTASEYIVHHLGHFSTKHQGSPFDMSILNMDTIFWSVFAGILGCGILYIAARRATSGVPGRFQAAIEMLVEMVEEQSKGIIHGDRTFIAPLALTVFVWVALMNSLDFLPVDLFARLFHYVGLEDVIGHHRVVPTADLNGTFGIALGVLVLILYYNVKIKGFGGFIHEIFSAPFGIWLAPFNLLLNLIEFAARTVSLAMRLFGNMFAGELIFLLIALLGATMTTFGIAGQILAGTVWAIFHILIVFLQAFIFMMLTLVYLGQAHEGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSK6</accession>
    <name>A0A2S9GSK6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4578</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000038">
        <property type="protein sequence ID" value="PRC90685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90685">
        <property type="protein sequence ID" value="PRC90685"/>
        <property type="gene ID" value="S2091_4578"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC90685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="40" mass="4420" checksum="84D21E93C163656D" modified="2018-07-18" version="1">MNIEKLNPDAPEVHVLITESNHYMAALYPAESNHIEGVDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSS2</accession>
    <name>A0A2S9GSS2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fe2+ transport system protein B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_4517</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000036">
        <property type="protein sequence ID" value="PRC90769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90769">
        <property type="protein sequence ID" value="PRC90769"/>
        <property type="gene ID" value="S2091_4517"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015093">
        <property type="term" value="F:ferrous iron transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01879">
        <property type="entry name" value="FeoB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011640">
        <property type="entry name" value="Fe2_transport_prot_B_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030389">
        <property type="entry name" value="G_FEOB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011642">
        <property type="entry name" value="Gate_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07664">
        <property type="entry name" value="FeoB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02421">
        <property type="entry name" value="FeoB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07670">
        <property type="entry name" value="Gate"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51711">
        <property type="entry name" value="G_FEOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="226"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="282"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="326"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="360"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="392"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="460"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="489"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="522"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="559"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="594"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="domain" description="FeoB-type G" evidence="2">
        <location>
            <begin position="8"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51711"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC90769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="619" mass="67691" checksum="E81E9323C18A621E" modified="2018-07-18" version="1">MNTVPSFSPLVALVGNPNCGKTALFNRLTGARQKVANFAGVTVERKIGRYVSGSGRTWQILDLPGTYSINASTPDEQITQAVITGQHQSEAMPDALVCVVDATNLRRGLRIALELKQLNLPMVLAVNMMDVADKRKIQIDLNALSAALAMPVVETVAVRAQGEASLLAALEKLPLRLEKNPPATLEPTSALELQKQVNQLLKDCVNNSAPASVWTEKIDRIILHPILGTALFLFLMFLVFQAVFSWAEWPMEIIKASVEGLGDLLHENMSEGVLRDLLTQGIIGGSGAVLVFLPQIVILFFFILVLEDSGYLPRAAFLLDRLMGSVGLSGRAFIPLLSSFACAIPGIMSTRTIQNPRDRLITIMIAPLMTCSARLPVYALIIAAFIPNKPILGILSLQGLVLFILYLAGILSAMLVAWVMKPRNKSTHALMLELPDYRWPNLRNLGLGLWERIRIFTTRVGTIILALMVLLWFLSSFPGAPDNATHPAIYYSIAGMLGRGLEVIFAPIGFNWQICIALVPGMAAREVAVAALGTVYALSQHGDNLAQTLQPLIAQSWSLPTALSLLAWFVFAPQCIATLSVVKRETNSWRYPLIMVSYLFGLAYLASFLTYRIALFFLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSV7</accession>
    <name>A0A2S9GSV7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4467</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000035">
        <property type="protein sequence ID" value="PRC90804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90804">
        <property type="protein sequence ID" value="PRC90804"/>
        <property type="gene ID" value="S2091_4467"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC90804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="221" mass="24452" checksum="6A93BD125239C1E7" modified="2018-07-18" version="1">MLKFIFICLLIANALLFALGRGYFASPIFEAHQPQRLLQQQNGDHLKLISAEMATAPVIPDVVEPTKSETFACLEWGSFLTTDLNQVEAKLKAIPFGNRQARQNVQDVATHIVFIPPLANKEAADKKALELTHLGVHDFFIISDQSAMRWGISLGVFKSEDAAKQLMATLVAKGVHSAKIGARTVATNKFNYVFKNVSGSERSDLDNLKTDFPEQDLHVCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSX4</accession>
    <name>A0A2S9GSX4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4476</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000035">
        <property type="protein sequence ID" value="PRC90813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90813">
        <property type="protein sequence ID" value="PRC90813"/>
        <property type="gene ID" value="S2091_4476"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015634380" evidence="1">
        <location>
            <begin position="23"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="141" mass="14933" checksum="2F6E6D8CBCD288AE" modified="2018-07-18" version="1">MSYFVKALFLFIIVLGMQSCYAQFAVVVGAKSEVAAMSADQVASLFLGKTDKFPNGSTALLLDQSSGSAIRNAFYDKVTGKNEAQIKAGWSRLVFSGKGTPPKEISGSQEVKKLVSANLNAVGYIEKSAVDASVKVLLSVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GT46</accession>
    <name>A0A2S9GT46_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major Facilitator Superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_4387</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000033">
        <property type="protein sequence ID" value="PRC90894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90894">
        <property type="protein sequence ID" value="PRC90894"/>
        <property type="gene ID" value="S2091_4387"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="28"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="66"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="98"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="123"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="155"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="191"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="257"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="290"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="322"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="346"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="380"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="414"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="32"/>
            <end position="437"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC90894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="437" mass="47896" checksum="5DA1E38D756D3B61" modified="2018-07-18" version="1">MLNQSDYPNANPSLTTSAQFDARLYRKIALRIIPFLFVCYVISFLDRINIGFAQLQMKTDLGFSDAMYGIGAAVFYIGYVLFEVPSNLLLEKIGARKTFVRIMLLWGLASVGMMFVVTPNHFYSLRFLLGVFEAGFFPGIVLYLTYWFPPARRAAVLAIFFAGVAVAGVLGGLVSGWIMQSMGGVMGMFGWQWMFLIEGSPALILAGIAYFYLDDKPQDAAWLNDAEKQRIAADLENENTLNIVTPTILSLLSTMRIYMFAFVYFSLTCASLTLSFWMPAMIRDFGVTDVVEISLYSVIPNALAIIGIITISRHSDHKNERVGHFVCCALGGAASLLLLTTHPGNFVLTMGLLSIATTLIFSALPIFWAIPTSYLSKKMAASGVALISSIGITSGIVSPYVIGQIKMATGGMDLAIYLLSGLLAGSCFVLVWVTRRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GT91</accession>
    <name>A0A2S9GT91_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Exosortase A system-associated hydrolase 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4340</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000032">
        <property type="protein sequence ID" value="PRC90939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90939">
        <property type="protein sequence ID" value="PRC90939"/>
        <property type="gene ID" value="S2091_4340"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017532">
        <property type="entry name" value="Hydrolase-2_PEP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022742">
        <property type="entry name" value="Hydrolase_4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12146">
        <property type="entry name" value="Hydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03101">
        <property type="entry name" value="hydr2_PEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hydrolase_4" evidence="1">
        <location>
            <begin position="37"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="282" mass="31339" checksum="5DFA33B4673B90B0" modified="2018-07-18" version="1">MSASPPPIQAFFLPTPIGQRFCLYHAPTLNKIDADLGSIVHVHAFAEEMNKCRRMAAMQARALAGLGYGVLQIDLYGCGDSSGDFADARWDIWKSDIVAGLNWLQQKHSKSLNLWGDRLGALLAMDVVRERREQINKLMLWQPVFSGEQFMTQFFRLLLANEMVSGKEQSVSGTKQIRAMLEAGETIEIAGYEIAADLAKQIDSLNAQDWLLPAGQLHWLEISNNAQNELAPARQLIADTWRQLGNSLQVHRLSGSAFWLAQETIIAPEWLNASCAIFAGAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTL8</accession>
    <name>A0A2S9GTL8_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_4252</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="PUGF01000030">
        <property type="protein sequence ID" value="PRC91064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91064">
        <property type="protein sequence ID" value="PRC91064"/>
        <property type="gene ID" value="S2091_4252"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013656">
        <property type="entry name" value="PAS_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013767">
        <property type="entry name" value="PAS_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00989">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08448">
        <property type="entry name" value="PAS_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PAC" evidence="8">
        <location>
            <begin position="117"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="7">
        <location>
            <begin position="177"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="8">
        <location>
            <begin position="259"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="7">
        <location>
            <begin position="319"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="8">
        <location>
            <begin position="390"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="5">
        <location>
            <begin position="460"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="6">
        <location>
            <begin position="741"/>
            <end position="864"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="4">
        <location>
            <position position="790"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC91064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="864" mass="93724" checksum="1A067AB301507826" modified="2018-07-18" version="1">MPKTGYGEGAGGPDGVMESKRKKILLKTGALQDAIFNSANFSSIATDEKGVIQIFNVGAERMLGYAAVDVVNQITPANISDPQELIARATALSLELDTPITPGFEALVFKASRGIEDIYELTYICKDGSRLPAIVSVTALRDAQENIIGYLLIGTDNTARKQAEEALLKAGALQTAIFNSANFSSIATDAKGVIQLFNVGAERMLGYAAAEVMNKITPADISDSQEVIMRAEALSLEVGTTIAPGFEALVFKAARGIEDIYELTYIRKDGSRFPAVVSVTALRDDQGAIIGYLLIGTDNTARKQVEAAKALTDQRLRDQQFYTRSLIESNIDALMTTDPQGIISDVNQQMMSLTGRTRDELIGAPCKNFFTDPVRADAAIRRVLTENKVSNYELTVRAQNGEETVVSYNAATFHDRERKLQGVFAAARDVTERKRFERALQEKNIELEHASGMKSEFLATMSHELRTPLNAIIGFSEALKDGLMGQMSATQQEYIGDIFTSGQHLLSLINDILDLSKVEAGMMALELEEVDLNNLLSNSLSIVREKAAAQHINLELETSDDLGVPHLDMRKTKQIVYNMLSNAVKFSANRGRVTLSARRVSRNTVGTLPGIWPVHSFPLADNEFNEFLEICVTDNGIGISKENMAKLFQAFSQIDSSLARKFEGTGLGLAMVKQLTELQGGAVAVASAEGNGARFAVWLPLRTSAQAAHTLPLVQKPISSNQLKASLTNLGVLSGEGHIRTVLVVDNDPKAVDMIAAFLPPPAYSVVRAYGGIEAIALAQRLRPDLVLLDLMMPEVSGFDVVLALRRNADTACIPILALTSKQITVQDRAALNSNPDKAIRIIEKAGFNRVGFIAEVTRALSPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTM7</accession>
    <name>A0A2S9GTM7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4234</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000030">
        <property type="protein sequence ID" value="PRC91046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91046">
        <property type="protein sequence ID" value="PRC91046"/>
        <property type="gene ID" value="S2091_4234"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010281">
        <property type="entry name" value="DUF885"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33361">
        <property type="entry name" value="PTHR33361"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05960">
        <property type="entry name" value="DUF885"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015510328" evidence="1">
        <location>
            <begin position="26"/>
            <end position="596"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="596" mass="66632" checksum="D6E86F3109F5D7C3" modified="2018-07-18" version="1">MIKQSFKVVSALLITFALSPMQSYAGTDSAATASVKSVFEEYWQDQLIDNPERATLLGDNRYSDRLHDLSPKATAKRKSDRLSFEKRLNGIDTQGLNAEDQISLSILRYQTHKNIVLDAIFGDLPFSADDLPFAITQMNGLQLGIPQLLRATSLKTTKDVEMLIKRLDALPVYIDQLTYVLRAGVKSGWMPAAITLKKVPSQFDPLLTTALENNPMFQPFIKLPNGISVADQDKLRKEAKEVILQHALPALGKLQTFLATEYLPAASEHIAASQLPGKLAFYQAMLVSSNTTLKTPEEIHQIGLSEVDKIEKAMLDVMKETGFKGTPAEFNLFMNTDPQFFFSNPEAMLASYRDIAKRIDARLPEQFETLPRLPYGIRAMMPSEGDGPEHYTTGALDGSRAGYFEANVNNLKRRANWSMEDLVLHEAVPGHHLQIARAGELTGFPTFRRAYFNSGYGEGWALYAESLGYDLGMYTSPYTRYGYLSSQIFRACRLVVDTGIHAFGMTREEAIDYLITHAAVTHDFAVAEVDRYIVWPGQATGYKLGQLEIIALRNKAEKTLGAKFDIRKFNNQVVDHGGLPLEILNNVINQWIVTQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTN5</accession>
    <name>A0A2S9GTN5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Binding-protein-dependent transport system inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_4173</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000029">
        <property type="protein sequence ID" value="PRC91077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91077">
        <property type="protein sequence ID" value="PRC91077"/>
        <property type="gene ID" value="S2091_4173"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="24"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="136"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="167"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="196"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="246"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="272"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="302"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="132"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC91077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="335" mass="36735" checksum="6891EAC8C24294BA" modified="2018-07-18" version="1">MPSTTQTSPGLWLLAWRRLQADRVAMLALTIVVAYLLLLLASATDIVASDWNKEIAVNYAPPTFIGTQKTMTGIEKTEEALAENPLDPLKEFIKELKVKSAAKTTEVAKRTSLPFGADKWGHDIIKKTIKGAETSIIVGLVAALLATFLGTLLGAFSGYFGGWIDDIFSWFYSIFTSIPYLLLILSVAAVLQQKGIGTIVLILALTGWTGTYRLIRAEYMKHKEREYVLAADAIGASHWRKMFAHIFPNVSHVALVQVSILVVSFIKSEVILSFLGFGVPVGMVSWGSMLNEAQNELILGKWWQLVAASVAMAVLVTAFSLFTDALRDALDPKLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUE2</accession>
    <name>A0A2S9GUE2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4001</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000025">
        <property type="protein sequence ID" value="PRC91330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91330">
        <property type="protein sequence ID" value="PRC91330"/>
        <property type="gene ID" value="S2091_4001"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="43" mass="4730" checksum="0696D6BF664FB467" modified="2018-07-18" version="1">MEVKDGLSANKTINEAYKSLRLQSSAYNSISFLVTEFLCAGVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUE5</accession>
    <name>A0A2S9GUE5_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PINc domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000024">
        <property type="protein sequence ID" value="PRC91355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91355">
        <property type="protein sequence ID" value="PRC91355"/>
        <property type="gene ID" value="S2091_3900"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09872">
        <property type="entry name" value="PIN_Sll0205-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002716">
        <property type="entry name" value="PIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041705">
        <property type="entry name" value="PIN_Sll0205"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01850">
        <property type="entry name" value="PIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="SSF88723"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PINc" evidence="1">
        <location>
            <begin position="2"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="131" mass="14599" checksum="C62B653639A31C86" modified="2018-07-18" version="1">MIVLDTHTLIWWVTGDPLLSKKAKAAINKEMVDGEIIVSSISAWEIAMLVERGRLFLSMDVASWLATVAKIDALHFMPVDVEVAMNSVKLPGDFHKDPADRMIVATARKLAATLVTKDEKIRAYAHVKTIW</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUG2</accession>
    <name>A0A2S9GUG2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3967</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000025">
        <property type="protein sequence ID" value="PRC91296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91296">
        <property type="protein sequence ID" value="PRC91296"/>
        <property type="gene ID" value="S2091_3967"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022134">
        <property type="entry name" value="DUF3667"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12412">
        <property type="entry name" value="DUF3667"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="99"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="240"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="278"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="325"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="352" mass="39778" checksum="3AF27B5C1BD201C8" modified="2018-07-18" version="1">MNAVSKVTNVLRFKKAGPKHHSAAHANTQCGNCSTKINGNFCHVCGQSAHVHHSLLHLIEEMVHGLWHFDAKGWRTIPMLFAFPGELTRRYIDGQRVRFISPLALFLFTVFFMFFMFSLTGSHNQDKEDSVVKFASTSIEQGLGKDLELATTNVDKAQANLLAAQKNGGDVSGSQHALDEAIEKQKVRQKDVGQTNEFTDHLVLGGMDLKEQQWVKKTIKHAIDNPEIVAYKMKNNAYKFALLLVPISLPFLWLMFFWRKGITMFDHAVFSFYSLSFMALWVSMMNALIAFHVTSAALIVLAFLPPIHMYRQLKSTYQLSHLSTLWRTVFLSFIACILLTIFMLFVAAVSAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUV9</accession>
    <name>A0A2S9GUV9_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">DNA repair protein RadA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">radA</name>
        <name evidence="9" type="ORF">S2091_3793</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.</text>
    </comment>
    <comment type="function">
        <text evidence="7">DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.</text>
    </comment>
    <comment type="function">
        <text evidence="6">Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.</text>
    </comment>
    <comment type="domain">
        <text evidence="6">The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6 7">Belongs to the RecA family. RadA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000022">
        <property type="protein sequence ID" value="PRC91515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91515">
        <property type="protein sequence ID" value="PRC91515"/>
        <property type="gene ID" value="S2091_3793"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000725">
        <property type="term" value="P:recombinational repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01121">
        <property type="entry name" value="Sms"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01498">
        <property type="entry name" value="RadA_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004504">
        <property type="entry name" value="DNA_repair_RadA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008269">
        <property type="entry name" value="Lon_proteolytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020588">
        <property type="entry name" value="RecA_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041166">
        <property type="entry name" value="Rubredoxin_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05362">
        <property type="entry name" value="Lon_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18073">
        <property type="entry name" value="Rubredoxin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00416">
        <property type="entry name" value="sms"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50162">
        <property type="entry name" value="RECA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6 7" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6 7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 6 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0346">Stress response</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RECA_2" evidence="8">
        <location>
            <begin position="68"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Lon-protease-like" evidence="6">
        <location>
            <begin position="352"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="RadA KNRFG motif" evidence="6">
        <location>
            <begin position="253"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="97"/>
            <end position="104"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00025580"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC91515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="457" mass="48849" checksum="06DF8051C9055CB8" modified="2018-07-18" version="1">MAKIKTNYSCTECGGVANKWAGQCPACGQWNTLVESLVETGTNRYSQAPQSLAQTAPVLQLSEIDALEVPRFSTGIDEFDRVLGGGLVSGGVVLIGGDPGIGKSTLLLQALAEMAKHKRVLYVSGEESGAQIALRSKRLGVENSELKLQAEIQLEKILSTLIQHKPQVVVIDSIQTMYSDALSSAPGSVAQVRECAAQLTRAAKLSDVTIIMVGHVTKEGALAGPRVLEHIVDTVLYFEGDTHSSFRLVRAIKNRFGAVNELGVFAMTERGLKGVSNPSALFLSQHDTPVPGACVMVTQEGSRPLLVEIQALVDASHAPNARRLSVGLEQNRLAMLLAVLHRHAGIAAFDQDVFINAVGGVKIVEPAADLAVLMAIHSSMRNRPLPRGLVVFGEVGLAGEIRPAPRGQERLREAAKLGFTIALIPKANAPKQQIDGLQIVAVDRIDQALSKLRELEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GV36</accession>
    <name>A0A2S9GV36_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">GGDEF: diguanylate cyclase (GGDEF) domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3686</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000021">
        <property type="protein sequence ID" value="PRC91570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91570">
        <property type="protein sequence ID" value="PRC91570"/>
        <property type="gene ID" value="S2091_3686"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="16"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="309"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="2">
        <location>
            <begin position="385"/>
            <end position="522"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="536" mass="58789" checksum="70D058A9770EBEF9" modified="2018-07-18" version="1">MTIKKPSGLSTISDSIFSFCVRIAVPLVLIAIVIAFQYKELQVDRAQHIEHAHLNAHDLGSTLATSIAGSFENIDLTLQAASDHIQLWRSVKEVDANAVKLALLKLQSRIPSMILLRAADANGHVVFYSRGDKSAMFNVSDRDYFQQLKNNVNAGMVISQPHMGRISNKWVLVCARRLNLPNGDFGGVVLASVELEGYINQLSGGIIKLSGDDVFLLRDEQSNALIRYAHGKQDMQIEGTKVSSTNLSELDRVGATTGSYVSKSAIDQIERVYYYQRIEGRPLNLVVGISVKDALAEWHVEVKKAWTETGMLILVILLATGLIYLARIRQQKAFSDLQSIQVVLEKTNQKLAKLSTTDGLTGLANRRKFDEIGPHEWQRALRKRESLAVAMVDVDFFKIYNDEYGHQAGDQCLIAIAKTLAAGLRDGSDFIARYGGEEFIILLPGQDAQGAFDVLERLRCDIEALALPHAGSDCASVITLSAGYAAMVPEARSTLAELIEKADQNLYSAKRNGKNRVLGASGWVSNASDANLIFGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GV37</accession>
    <name>A0A2S9GV37_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 14">Crossover junction endodeoxyribonuclease RuvC</fullName>
            <ecNumber evidence="11 14">3.1.21.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13 14">Holliday junction nuclease RuvC</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12 14">Holliday junction resolvase RuvC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">ruvC</name>
        <name evidence="15" type="ORF">S2091_3690</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9 14">Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 14">
            <text>Endonucleolytic cleavage at a junction such as a reciprocal single-stranded crossover between two homologous DNA duplexes (Holliday junction).</text>
            <dbReference type="EC" id="3.1.21.10"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="14">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="14">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 14">Belongs to the RuvC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.21.10" evidence="11 14"/>
    <dbReference type="EMBL" id="PUGF01000021">
        <property type="protein sequence ID" value="PRC91574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91574">
        <property type="protein sequence ID" value="PRC91574"/>
        <property type="gene ID" value="S2091_3690"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008821">
        <property type="term" value="F:crossover junction endodeoxyribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd16962">
        <property type="entry name" value="RuvC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00034">
        <property type="entry name" value="RuvC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020563">
        <property type="entry name" value="X-over_junc_endoDNase_Mg_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002176">
        <property type="entry name" value="X-over_junc_endoDNase_RuvC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30194">
        <property type="entry name" value="PTHR30194"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02075">
        <property type="entry name" value="RuvC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00696">
        <property type="entry name" value="RSOLVASERUVC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00228">
        <property type="entry name" value="ruvC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01321">
        <property type="entry name" value="RUVC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 14" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7 14" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="8 14" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 14" id="KW-0460">Magnesium</keyword>
    <keyword evidence="14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 14" id="KW-0540">Nuclease</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="14">
        <location>
            <position position="7"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="66"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="138"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="141"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009518"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00014685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00029354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00029488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00030265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00030973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="PRC91574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="180" mass="18968" checksum="5FF78A65A2E7CCAC" modified="2018-07-18" version="1">MKILGIDPGLRTTGFGLIEKQGQKIFYLASGTIKTADGTLPERLKTIFKSVAEIVATYQPDCAAIEIVFVNVNPQSTLLLGQARGAAICALVNADLEVSEYTALQVKQGVVGHGKAKKEQVQEMVQRLLQLPSLPGPDAADALGVAICHAHSLDTLAALSKLAPGIAKRGMRVRGGRLVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVH6</accession>
    <name>A0A2S9GVH6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative hydrolases or acyltransferases (Alpha/beta hydrolase superfamily)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3604</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000020">
        <property type="protein sequence ID" value="PRC91666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91666">
        <property type="protein sequence ID" value="PRC91666"/>
        <property type="gene ID" value="S2091_3604"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000639">
        <property type="entry name" value="Epox_hydrolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00412">
        <property type="entry name" value="EPOXHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="26"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="271" mass="29017" checksum="B68216267FE2EAF9" modified="2018-07-18" version="1">MIYQVQGNPVYCYTGGKAFQAELATLVFIHGAQNDHSVWALQSRYLAHHGYNVLAVDLPGHGRSAGNALTSIEDMATWLLALLDVAGVVGEAKASLIGHSMGSLIALETARCAPDRVTKLALLGNAYPMKVADALLTMARDDEAAAIDMVNSWSHCTSTQQSAIPGFNVQGNAQRLMQRMSAINPAQLFYTDFSACNNYQQGEAAAVAINSQQCPTLFVMAKQDRMTPVKASATLRSSILGSKVVEIANCGHSLMTEQPDAVLTALVQFLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVQ1</accession>
    <name>A0A2S9GVQ1_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Glyceraldehyde-3-phosphate dehydrogenase</fullName>
            <ecNumber evidence="8">1.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">S2091_3560</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.-" evidence="8"/>
    <dbReference type="EMBL" id="PUGF01000019">
        <property type="protein sequence ID" value="PRC91805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91805">
        <property type="protein sequence ID" value="PRC91805"/>
        <property type="gene ID" value="S2091_3560"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016620">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006006">
        <property type="term" value="P:glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020831">
        <property type="entry name" value="GlycerAld/Erythrose_P_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020830">
        <property type="entry name" value="GlycerAld_3-P_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020829">
        <property type="entry name" value="GlycerAld_3-P_DH_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020828">
        <property type="entry name" value="GlycerAld_3-P_DH_NAD(P)-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006424">
        <property type="entry name" value="Glyceraldehyde-3-P_DH_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43148">
        <property type="entry name" value="PTHR43148"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02800">
        <property type="entry name" value="Gp_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00044">
        <property type="entry name" value="Gp_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000149">
        <property type="entry name" value="GAP_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00078">
        <property type="entry name" value="G3PDHDRGNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00846">
        <property type="entry name" value="Gp_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01534">
        <property type="entry name" value="GAPDH-I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00071">
        <property type="entry name" value="GAPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gp_dh_N" evidence="9">
        <location>
            <begin position="3"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Glyceraldehyde 3-phosphate binding" evidence="4">
        <location>
            <begin position="154"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Glyceraldehyde 3-phosphate binding" evidence="4">
        <location>
            <begin position="213"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="3">
        <location>
            <position position="155"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="12"/>
            <end position="13"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="37"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="81"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="123"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="185"/>
        </location>
        <ligand>
            <name>D-glyceraldehyde 3-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="236"/>
        </location>
        <ligand>
            <name>D-glyceraldehyde 3-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="318"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="site" description="Activates thiol group during catalysis" evidence="6">
        <location>
            <position position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000149-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000149-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000149-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000149-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC91805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="337" mass="36075" checksum="28A6AEFDD3FE6BE9" modified="2018-07-18" version="1">MTIRVAINGYGRIGRNILRAHYEGGKKHDIQIVAINDLGAPASNAHLTQYDTAHGKFPGTVTVDGDYMIVNGDKIRVFAERNPANLPWGEVGVDVVLECTGFFTTKEKASAHLVGGAKKVIISAPGGKDVDATVVFGVNHEVLKSTDTVISNASCTTNCLAPLAKSLNDAVGIESGLMTTIHSYTNDQVLTDVMHEDLRRARSATQSMIPAKTGAAAAVGLVLPELNGKLDGYAIRVPTINVSIVDLTFISKRPTTVEEINQIMKTASESAALKGILDYNTAPLVSVDFNHNPASSTFDETLTKVSGNLVKVSSWYDNEWGFSNRMLDTTVALMNAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVW7</accession>
    <name>A0A2S9GVW7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Beta-lactamase class C and other penicillin binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3423</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000018">
        <property type="protein sequence ID" value="PRC91867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91867">
        <property type="protein sequence ID" value="PRC91867"/>
        <property type="gene ID" value="S2091_3423"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta-lactamase" evidence="1">
        <location>
            <begin position="163"/>
            <end position="434"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="457" mass="49547" checksum="9675CA6D0828616C" modified="2018-07-18" version="1">MISRWKLAASAVLFLFCAGLIWLAYAPPDLIRVGANYSAKIICSNVFLAGRDANEVLALDVQAPGHPLLKLMRVQVDREHGLVSANILGFIGDGLAVFRPGTGCAAVPDGDVALARKYQMKVAALPLPSANAAWPVGSKAEVNEKVENIISQEVLNGPGMRGIAVIHQGKLIAQRYGAGFDEHTPLIGWSMTKTVNAALIGIQVGEGKLRLNQDGFWRTATPSDGREKIKLADLLAMSSGLHFDEEYGDVSDVTRMLYLEPDMATFVHDQALEHPAGSVWNYSSGTSVLLAQIWQQVAGADALRFPQQRLFAPLGMTSALLEADARGNLVGASYLYATAQDWARFGQLLLQDGVWNGRHLLPEGYVKMMLSAVPASKGKYGQGQIWLEGPGPDTPEGKSPDTPFMLPKDTYWMQGHDGQTIAIIPSKQLVVVRLGLTPRKFMYMPQAMLAEIIKATD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVW9</accession>
    <name>A0A2S9GVW9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">FlxA-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3425</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000018">
        <property type="protein sequence ID" value="PRC91869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91869">
        <property type="protein sequence ID" value="PRC91869"/>
        <property type="gene ID" value="S2091_3425"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025577">
        <property type="entry name" value="FlxA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14282">
        <property type="entry name" value="FlxA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="117" mass="12666" checksum="9CB536D943F06139" modified="2018-07-18" version="1">MADLLTQVSSGIVLGTDSSGDIATDIQKLMKQIAQVEKSIKNLINDGSVAPNDKIKQLKLLQGTLTLLYQALTQLMELQTKQKENQTNIIEKIPAQTAAQKNNGSAIIPDTNIDTFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVY4</accession>
    <name>A0A2S9GVY4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HhH-GPD superfamily base excision DNA repair protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3441</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000018">
        <property type="protein sequence ID" value="PRC91885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91885">
        <property type="protein sequence ID" value="PRC91885"/>
        <property type="gene ID" value="S2091_3441"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00056">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011257">
        <property type="entry name" value="DNA_glycosylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003265">
        <property type="entry name" value="HhH-GPD_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00730">
        <property type="entry name" value="HhH-GPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00478">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48150">
        <property type="entry name" value="SSF48150"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ENDO3c" evidence="1">
        <location>
            <begin position="54"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="212" mass="24326" checksum="146A67F500D5CD4F" modified="2018-07-18" version="1">MIIQPHRELPAYWEQAKQELMKRDRIMRKLIPQFGDLHLAGRGEPFLTLCRSIIGQQISVAAADAVWGRFLAACTKCTPVNVLNAGSEQLLACGLSKRKTEYILDLAEHFKEKRVHVEKWAEMDDEDVISELIQIRGIGRWTAEMFLIFNLLRPNILPLDDLGLLKGISINYFSGEPVSRSDAREVAANWEPWRTVATWYLWRSLDSVAVEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GW04</accession>
    <name>A0A2S9GW04_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">23S rRNA (guanosine-2'-O-)-methyltransferase RlmB</fullName>
            <ecNumber evidence="6">2.1.1.185</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">23S rRNA (guanosine2251 2'-O)-methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">23S rRNA Gm2251 2'-O-methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rlmB</name>
        <name evidence="8" type="ORF">S2091_3458</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Specifically methylates the ribose of guanosine 2251 in 23S rRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>guanosine(2251) in 23S rRNA + S-adenosyl-L-methionine = 2'-O-methylguanosine(2251) in 23S rRNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:24140"/>
            <dbReference type="Rhea" id="RHEA-COMP:10239"/>
            <dbReference type="Rhea" id="RHEA-COMP:10241"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74269"/>
            <dbReference type="ChEBI" id="CHEBI:74445"/>
            <dbReference type="EC" id="2.1.1.185"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.185" evidence="6"/>
    <dbReference type="EMBL" id="PUGF01000018">
        <property type="protein sequence ID" value="PRC91902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91902">
        <property type="protein sequence ID" value="PRC91902"/>
        <property type="gene ID" value="S2091_3458"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070039">
        <property type="term" value="F:rRNA (guanosine-2'-O-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01887">
        <property type="entry name" value="23SrRNA_methyltr_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024915">
        <property type="entry name" value="23S_rRNA_MeTrfase_RlmB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029064">
        <property type="entry name" value="L30e-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004441">
        <property type="entry name" value="rRNA_MeTrfase_TrmH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001537">
        <property type="entry name" value="SpoU_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013123">
        <property type="entry name" value="SpoU_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46429">
        <property type="entry name" value="PTHR46429"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00588">
        <property type="entry name" value="SpoU_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08032">
        <property type="entry name" value="SpoU_sub_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00967">
        <property type="entry name" value="SpoU_sub_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55315">
        <property type="entry name" value="SSF55315"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="SSF75217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00186">
        <property type="entry name" value="rRNA_methyl_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 6 8" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="5 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 6 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SpoU_sub_bind" evidence="7">
        <location>
            <begin position="5"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="198"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="227"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC91902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="246" mass="26334" checksum="A1C2AC04F34666DF" modified="2018-07-18" version="1">MKSKFIFGFHAVTARLRHEAASVEEIYVDTGRQDRRMLELISAAKGAGVRVIPVDELRLANMVGTRRHQGVVAKAGEISLARNLDELLDAIEGPALILILDGITDPHNLGACLRVADGAGAHAVIAPKDRAVGLNATAAKVASGAADTMPYITVTNLARTMRELKERNIYVVGTSDDAEKSLYQADFTGGEGVALVMGSEGEGIRRLTRDTCDFLVSVPMFGSVESLNVSVASGICLYEARRQRLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GW27</accession>
    <name>A0A2S9GW27_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3264</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000017">
        <property type="protein sequence ID" value="PRC91922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91922">
        <property type="protein sequence ID" value="PRC91922"/>
        <property type="gene ID" value="S2091_3264"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="146" mass="15811" checksum="B7D1F50B893ADCD3" modified="2018-07-18" version="1">MLRLVVELPPSWVDLSSENADGPSTFIKEDPESTGALQISIQAEYHGGTIPNPIPEQLVSYAEGIVNKNAHVQIRGRSTGKCKMGTYGTVLASLLRHSWCQIWVLSNGNDFVLASHTSVDEPSEAEVNEASWVVKNISLQAIPVGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GW64</accession>
    <name>A0A2S9GW64_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ergothioneine biosynthesis protein EgtB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3305</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000017">
        <property type="protein sequence ID" value="PRC91963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91963">
        <property type="protein sequence ID" value="PRC91963"/>
        <property type="gene ID" value="S2091_3305"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052699">
        <property type="term" value="P:ergothioneine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1580.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024775">
        <property type="entry name" value="DinB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034660">
        <property type="entry name" value="DinB/YfiT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017806">
        <property type="entry name" value="EgtB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005532">
        <property type="entry name" value="SUMF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042095">
        <property type="entry name" value="SUMF_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12867">
        <property type="entry name" value="DinB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03781">
        <property type="entry name" value="FGE-sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109854">
        <property type="entry name" value="SSF109854"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="SSF56436"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03440">
        <property type="entry name" value="egtB_TIGR03440"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DinB_2" evidence="2">
        <location>
            <begin position="12"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="domain" description="FGE-sulfatase" evidence="1">
        <location>
            <begin position="198"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="399" mass="46273" checksum="F90B0BE0FF308B96" modified="2018-07-18" version="1">MSATLTLIERWTKTREYSLRIAAYLSAEDAAAQSMPDASPIKWHLAHTTWFFETFILETFDPDFHAFHPAFKLLFNSYYNGIGEQYPRPQRGLLTRPDLKEVLEYRHAVDERIQLLYQHHSSIKCDELIELGIQHEQQHQELMLTDIKHLLSSNPLNPVMLAEDTGILDTVDAIPAAIDWHYFEPALQEIGHHEAGFCFDNETPRHRQFIEEFQLASRLVNNGEYLAFIEAGGYTNPTLWLADGWNWIIQQQIKHPLYWRHTNHWQEFTLHGLHELDPLQPVCHLSFFEASAYASWVGARLPTEAEWEYAAQKNAQLTQLFACCWQWTSSSYAPYPGYAIAEGAIGEYNGKFMVNQYVLRGSSAFTPKHHSRLTYRNFFPASARWQRTGIRLARSIGKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GW81</accession>
    <name>A0A2S9GW81_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Electron transfer flavoprotein domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3321</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000017">
        <property type="protein sequence ID" value="PRC91979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91979">
        <property type="protein sequence ID" value="PRC91979"/>
        <property type="gene ID" value="S2091_3321"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014730">
        <property type="entry name" value="ETF_a/b_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01012">
        <property type="entry name" value="ETF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0249">Electron transport</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ETF" evidence="2">
        <location>
            <begin position="37"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="276" mass="29724" checksum="211B02AE735BE0F7" modified="2018-07-18" version="1">MANELNMNMSETAPLKIAVLLSPAQHAVSGHPLRSSSDAAAFELACSLAPEQRLTILCAGMVSKESLNDYLGLGASAIEVLTVEQGADVVAALQARLQGFDIVLCGVRSDGQSGSGLLPYLLAEGLQMPLVADVLEAKFQTKGLQAQLQLRQFLPKGMRRRLEVSLPVLLTVHARAPQTRQYAYARARSGRISYVAGKHQSNGTNDTPSQAWNIEPALRRPRPLKAKIVQSGHSRMLGAIGGDTEVRASVVLKEGSAEQKAQALLAYLREHHLVDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWA9</accession>
    <name>A0A2S9GWA9_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Arsenate reductase</fullName>
            <ecNumber evidence="3">1.20.4.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_3351</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>[glutaredoxin]-dithiol + arsenate + glutathione + H(+) = arsenite + glutathionyl-S-S-[glutaredoxin] + H2O</text>
            <dbReference type="Rhea" id="RHEA:22016"/>
            <dbReference type="Rhea" id="RHEA-COMP:10729"/>
            <dbReference type="Rhea" id="RHEA-COMP:17668"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29242"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:48597"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:146199"/>
            <dbReference type="EC" id="1.20.4.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 2 3">Belongs to the ArsC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.20.4.1" evidence="3"/>
    <dbReference type="EMBL" id="PUGF01000017">
        <property type="protein sequence ID" value="PRC92009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92009">
        <property type="protein sequence ID" value="PRC92009"/>
        <property type="gene ID" value="S2091_3351"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008794">
        <property type="term" value="F:arsenate reductase (glutaredoxin) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03034">
        <property type="entry name" value="ArsC_ArsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006659">
        <property type="entry name" value="Arsenate_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006660">
        <property type="entry name" value="Arsenate_reductase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30041">
        <property type="entry name" value="PTHR30041"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03960">
        <property type="entry name" value="ArsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00014">
        <property type="entry name" value="arsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51353">
        <property type="entry name" value="ARSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU362029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC92009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="141" mass="15929" checksum="2ED663F66100132E" modified="2018-07-18" version="1">MTVTIYHNPQCGTSRNTLELIRNTGVEPEIIEYLINPPSRSKLVELIAAMNIPVRDLLRKKGTPYDELNLDDPNLTDATLIDFMLAHPILINRPIVETPLGTKLCRPSELVLDILPLPQLKEFTKEDGEKVINTEGRRVSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWF1</accession>
    <name>A0A2S9GWF1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3190</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000016">
        <property type="protein sequence ID" value="PRC92055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92055">
        <property type="protein sequence ID" value="PRC92055"/>
        <property type="gene ID" value="S2091_3190"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07377">
        <property type="entry name" value="WHTH_GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00392">
        <property type="entry name" value="GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50949">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="2">
        <location>
            <begin position="14"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="474" mass="52738" checksum="C9C591D9F07FE807" modified="2018-07-18" version="1">MNSPTQALVRDSTDTLVDQIVRIIENKIDDKLLRTGARMPSIRRYAETCEVSRFTVVEAYDRLVARGYLESRRGSGFFVRERAPLTATPQAPTNPQQLDVVWLVRNMFRQMPPHKMPGSGVLPHDWLDGELVANGLRAVSRLNQNLLLHYGTPQGFYPLRQQLQLRLAELEIAATPEQIVTTSGVTQALDLVAREFAHPGDTILVDDPAWFLMFGSFAVLGVKVIGIPRQQDGPDIAALCEMAALHKPKLYITNSVLHNPTSTSMSAAKAFQVLKAAELHDFIIVEDDIYSDLHPGNSIQAATRVASLDQLNRVIYLGGFSKLLAANLRVGFIATSHELASRLSDRKMLSTLTTTEIGERVVYKILSEGHYRKYIERVRSKLDPVRLSTAKQLENIGVKVDIFTPAGMFLWVDAGCDTNALAEAALEQGILLSPGSMFSPNQQPSTRMRINVAAMTDPLVWRFLKEEIKVRSSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWR0</accession>
    <name>A0A2S9GWR0_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_3054</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92138">
        <property type="protein sequence ID" value="PRC92138"/>
        <property type="gene ID" value="S2091_3054"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="151"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="5">
        <location>
            <begin position="235"/>
            <end position="447"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC92138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="450" mass="50086" checksum="A4B3B96E48A2A900" modified="2018-07-18" version="1">MFKPTLVRRVVTAIFIAFSVIWLVLTTYKYITERNTDDVRAGMSSFIQYEMQGFDTASTAPEAIQYAFSLEREFNRSRRSDGRHDVLMELSDQHGKRLFWVTDHPLKGILNQVVPTQLDGKDYLIFRGETALWTFQIAYPILTVGDAVRKFGSVIGTLMLIAFPFILLPIWYAVWRGLHPLRTLSALIAARHTDDLSPVDFDPYYGELKPVVSAINRLLNQLSKKIAREHAFVQDAAHELRTPLAVISAHVHVLAKADTFQEKLEAEQRVDNAIARASHLVQQLLELARVDGKPLENLAPLDASHLTRLTLAQAAPAAKARQIELSLDAPDKLPHPMEMHAFQSILHNLVDNAIRYIHPGGKIIVKLKRQANTLTLTVADDGPGIAEEDRSAVFERFYRGKAHDLPGSGLGLAIVQQAAARMGGEVLLSTGLVGRGCQFTVVIPTVTARI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWX9</accession>
    <name>A0A2S9GWX9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Glutaredoxin-like domain (DUF836)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3138</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92222">
        <property type="protein sequence ID" value="PRC92222"/>
        <property type="gene ID" value="S2091_3138"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008554">
        <property type="entry name" value="Glutaredoxin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05768">
        <property type="entry name" value="Glrx-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="75" mass="8349" checksum="25F565C4B71FD963" modified="2018-07-18" version="1">MRAALEKQLIDIPYQLTILDVDQDPDLLALYDELVPVLCARLSSDVTVSGAGQQLCHYFLDGEKVNALIESTRNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWY0</accession>
    <name>A0A2S9GWY0_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">7-methyl-GTP pyrophosphatase</fullName>
            <shortName evidence="3">m(7)GTP pyrophosphatase</shortName>
            <ecNumber evidence="3">3.6.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_3124</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>H2O + N(7)-methyl-GTP = diphosphate + H(+) + N(7)-methyl-GMP</text>
            <dbReference type="Rhea" id="RHEA:58744"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58285"/>
            <dbReference type="ChEBI" id="CHEBI:87133"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the Maf family. YceF subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.-" evidence="3"/>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92208">
        <property type="protein sequence ID" value="PRC92208"/>
        <property type="gene ID" value="S2091_3124"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047429">
        <property type="term" value="F:nucleoside-triphosphate diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009117">
        <property type="term" value="P:nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00555">
        <property type="entry name" value="Maf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00528">
        <property type="entry name" value="Maf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029001">
        <property type="entry name" value="ITPase-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003697">
        <property type="entry name" value="Maf-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43213">
        <property type="entry name" value="PTHR43213"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02545">
        <property type="entry name" value="Maf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006305">
        <property type="entry name" value="Maf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52972">
        <property type="entry name" value="SSF52972"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00172">
        <property type="entry name" value="maf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 3" id="KW-0546">Nucleotide metabolism</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="75"/>
        </location>
    </feature>
    <feature type="site" description="Important for substrate specificity" evidence="3">
        <location>
            <position position="18"/>
        </location>
    </feature>
    <feature type="site" description="Important for substrate specificity" evidence="3">
        <location>
            <position position="76"/>
        </location>
    </feature>
    <feature type="site" description="Important for substrate specificity" evidence="3">
        <location>
            <position position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC92208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="203" mass="22192" checksum="5286248C0FEEC503" modified="2018-07-18" version="1">MTVLCNENRIILASSSIYRKELLSRLNLPFEVMIPDIDEIAFPSETPQATALRLAEQKARAIAKIAPGAIIIGSDQVATLNNLHIGKPGNHQNALAQLQMMRGKQVIFHSALCVYQDCQPMPLVQVENVQTSVTFRDLSDAELDAYLRIEQPYDCAGSAKNEGLGIAILERIDSSDPTALTGLPLITLTSMLRKAGVSFFKPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GX05</accession>
    <name>A0A2S9GX05_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">HDIG: uncharacterized domain HDIG</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2909</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92250">
        <property type="protein sequence ID" value="PRC92250"/>
        <property type="gene ID" value="S2091_2909"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008081">
        <property type="term" value="F:phosphoric diester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021812">
        <property type="entry name" value="DUF3391"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037522">
        <property type="entry name" value="HD_GYP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006675">
        <property type="entry name" value="HDIG_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11871">
        <property type="entry name" value="DUF3391"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01966">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00277">
        <property type="entry name" value="HDIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51831">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51832">
        <property type="entry name" value="HD_GYP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HD-GYP" evidence="2">
        <location>
            <begin position="163"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="domain" description="HD" evidence="1">
        <location>
            <begin position="185"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="434" mass="48037" checksum="7ECB06663CDFB235" modified="2018-07-18" version="1">MQNLPRRDSYIMPDQLCVGLYVHLDLNWTKHPFSFSSFKIEKTDQIDTIRGLGLQRIRYTPNKSDCYPVEVANDPNVTAPVAAKNAADPVIYAEAVIEAPDGTIFKEKHQLIDRMAQQGEKILACEREFAAALRALKLMWQNMFANPAAVAEQAGSMVGKMAESTLMESEIAIHLMIDHKNGSDIYTHALNVAVLSMILAKEMGRSLEDIKLIGLGALFHDVGCTDAPRRIKEKSEPLTTMEAATMHQHCKQGVDICNRLQLPYEAVLIVWQHHERIDGSGYPAKLRDKQLSPLASIVAVADAYDEICNPINSAQARTPHESLSLIYAQQRTRFDGKALTALVHCLGVYPPGTIVLLSNGIIGMVVAVNTKRPLKPTVLVYDPATAKNEAILIDLEQEVDVSITKTISPHQLSPEIFEFLAPGKRASYYMRAVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GX35</accession>
    <name>A0A2S9GX35_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cold shock protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_2941</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92282">
        <property type="protein sequence ID" value="PRC92282"/>
        <property type="gene ID" value="S2091_2941"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04458">
        <property type="entry name" value="CSP_CDS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012156">
        <property type="entry name" value="Cold_shock_CspA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011129">
        <property type="entry name" value="CSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019844">
        <property type="entry name" value="CSD_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002059">
        <property type="entry name" value="CSP_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00313">
        <property type="entry name" value="CSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002599">
        <property type="entry name" value="Cold_shock_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00050">
        <property type="entry name" value="COLDSHOCK"/>
    </dbReference>
    <dbReference type="SMART" id="SM00357">
        <property type="entry name" value="CSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00352">
        <property type="entry name" value="CSD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51857">
        <property type="entry name" value="CSD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CSD" evidence="3">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC92282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="67" mass="7238" checksum="68FC5E37054A3F20" modified="2018-07-18" version="1">MATGIVKWFNDSKGFGFITPDEGGEDLFAHFSAIQSAGFKTLKENQRVSFEVTTGPKGKQASNIQGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GX80</accession>
    <name>A0A2S9GX80_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative phosphatase homologous to the C-terminal domain of histone macroH2A1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2969</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92310">
        <property type="protein sequence ID" value="PRC92310"/>
        <property type="gene ID" value="S2091_2969"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.220.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002589">
        <property type="entry name" value="Macro_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043472">
        <property type="entry name" value="Macro_dom-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01661">
        <property type="entry name" value="Macro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00506">
        <property type="entry name" value="A1pp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52949">
        <property type="entry name" value="SSF52949"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51154">
        <property type="entry name" value="MACRO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Macro" evidence="1">
        <location>
            <begin position="1"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="172" mass="18055" checksum="BE1A08D94C804277" modified="2018-07-18" version="1">MPAIIKAVHADITKMQVDAIVNAANSSLLGGGGVDGAIHRAAGVDLVHECRLLGGCKTGEAKLTKGYLLPAKYIIHTVGPVWRGGTNGESDLLRLCYSISIDIAAKQGISTLAFPSISTGIYGYPIELAAEVAVITVRAAVQQYSNIKEVMFCCFSGSDLAVYEKVLNEASV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXH9</accession>
    <name>A0A2S9GXH9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative ACR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3025</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0166 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92366">
        <property type="protein sequence ID" value="PRC92366"/>
        <property type="gene ID" value="S2091_3025"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003793">
        <property type="entry name" value="DUF190"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011322">
        <property type="entry name" value="N-reg_PII-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015867">
        <property type="entry name" value="N-reg_PII/ATP_PRibTrfase_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02641">
        <property type="entry name" value="DUF190"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54913">
        <property type="entry name" value="SSF54913"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF190" evidence="2">
        <location>
            <begin position="6"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="106" mass="12049" checksum="7BEB7BE8AA050EC6" modified="2018-07-18" version="1">MQGYQLEFFMEQNKRHGHQALYEWLLDLARSQGIAGATVFMGAMGFGHHSRMHSAHFFELADQPVLVTMVVEQSESVELFALIEKEQVHMFYVKMPVEFGSLGAQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXJ2</accession>
    <name>A0A2S9GXJ2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Bacterial regulatory helix-turn-helix protein, lysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2808</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92433">
        <property type="protein sequence ID" value="PRC92433"/>
        <property type="gene ID" value="S2091_2808"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="5"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="300" mass="33872" checksum="A26BED5A28B21A6F" modified="2018-07-18" version="1">MINNLTLHQLRCFDAVVTQGSFQAAANQLFRSQPTVFAAVKSLEAQVGVNLLDRSSYRVKVTDAGRSFHARTRVFLQEYGKLENHVTQLSMGVESELRVVIGDLCPLTETLNLLRRFFDNCPGTRLHLHFEAISGPWERLNDGDADLIFHHIDTSDPSLEYINLQNVKLIPVVAPNFLSFPITDAISPEQMRDYVQCVIRDSARHSAPRDYYVMEGTRSWTVSDQLMKKEVIVQGMGWGHMPDFLIEDELRSGSLLSIAGKYLRGGQVGLVAARNRNIPHGPVAELLWSYIEDHLHSTNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXJ3</accession>
    <name>A0A2S9GXJ3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2803</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92428">
        <property type="protein sequence ID" value="PRC92428"/>
        <property type="gene ID" value="S2091_2803"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015728489" evidence="1">
        <location>
            <begin position="34"/>
            <end position="445"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="445" mass="50778" checksum="0F7C4237C2AD8440" modified="2018-07-18" version="1">MQFFQTLPKTTQYLRCVASLLFLMLTSISITHAESMPDTPLQVSPKTDRLKDLNKSIKYAEDINASKTLDDRQKYFIVSQNFESVASDESMIGDVFGAMNQYGKYNKYLEERELKKSNSRSNLNSRETSVTEDIQHQIQEATVQDAIEVIVNEAKHRQIVILNEAHHVPMHRAFAMLLARELKKIGYDYLACEAFTNLGSTPPLAKGYVSEDSGIYTRESMYADFLREAIQSHWKFISYEPTERAREYYMAKNLVDRIFKQNPKAKVFIYVGYAHGNKLPKSEDENDRSMMAAQLQKMTGINPLTIDQTTLFQQYVNKIQIAAYNEAVKSHQIEKPSVLITPQNTYLKLGHNFLSGEAYDIQVIYPTYENNPETGRASWLESMAGLNPENIPSKLIPKKGKRLIYAYSSKEPADAVPVDVVLVEAGKPIPKLMLPKGNFRYAFED</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GY11</accession>
    <name>A0A2S9GY11_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2658</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92603">
        <property type="protein sequence ID" value="PRC92603"/>
        <property type="gene ID" value="S2091_2658"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015573186" evidence="1">
        <location>
            <begin position="19"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="192" mass="20210" checksum="12A3F5367EE189FE" modified="2018-07-18" version="1">MKKLFALTPLLLSLFGCASTDSNSESTAVAGPTTTTAQARIGKAVVSPLTDLNLMPTNIPAVITQALNNPYQLPVNINCEALSEQVQALNAALGPDLDTFSREDKRTNIEKGSAMASDSAVGAIESTISGAVPFRSWLRKLSGAEKKSKELNEAIAAGIVRRSYLKGMGEALKCLPPAAPLNHETVTAQKSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GY65</accession>
    <name>A0A2S9GY65_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2703</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92648">
        <property type="protein sequence ID" value="PRC92648"/>
        <property type="gene ID" value="S2091_2703"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="70" mass="7656" checksum="665B035FD00C72C9" modified="2018-07-18" version="1">MTTLNENIPLADASDFLGLITERIRDAQGHHIYKCPNVPAEGMQVLDNFLAGWIKTYCACVDAACSEAMP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GY90</accession>
    <name>A0A2S9GY90_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2681</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92626">
        <property type="protein sequence ID" value="PRC92626"/>
        <property type="gene ID" value="S2091_2681"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1440.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036583">
        <property type="entry name" value="23S_rRNA_IVS_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="281" mass="31070" checksum="5CE3EE9C0A125E85" modified="2018-07-18" version="1">MNTVRPTKDEQQQFRISSFKGIDVGLGQADPVASISAKLEAQYPNHLILVQAGKFLHGYDKSAHALSVLKQYKVQLVGTTDAPHIRVGFPSSNFKKRLWSIVNDFQIPYVVALGTKASGHDIFVSDNFQGKSSVLSAISNDVVSQVIYDLQQRGEINKVTTKQILSNPDSSGFKLKSQAQDLDLHLTQDIIKMPRDIRVTFGENIRVCMARIMRGIFAYGLEVQKSALLNKISADIDLLKHYLAQAARLNNLKFAFEHRVGLAVELGRLLGGVIRAAKVPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYA9</accession>
    <name>A0A2S9GYA9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nucleoside-diphosphate-sugar epimerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2442</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92712">
        <property type="protein sequence ID" value="PRC92712"/>
        <property type="gene ID" value="S2091_2442"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="1">
        <location>
            <begin position="5"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="314" mass="33844" checksum="BF00FCA722C2234C" modified="2018-07-18" version="1">MNKHILLTGASGFVGGPLAQHLIAQGAQMTCVVRTPFQLSGAQMVTVDGIDDSTDWTASLKGIDTVIHCAARVHIMNDTSPDPLADFRRINVAGTLNLARQALAAGVNRFIYLSSIKVNGEHTDLGKAFNELDKPDPQDSYGVSKFEAEQALLELSSITGLEVVIIRPPLVYGPGVKANFLNMLKLVRSGIPLPFGAINNKRSFVYVENLISLITLCIDHPNAANQVFLVSDGCDLSTTELLRQFAGGLGVKQWLLPVPESWLTIAAMLLGKKAVAQRLCGSLQVDTSKARQLLGWEPPMSVEQGMKLTAKSLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYD3</accession>
    <name>A0A2S9GYD3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2465</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92735">
        <property type="protein sequence ID" value="PRC92735"/>
        <property type="gene ID" value="S2091_2465"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="84"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="96"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="113" mass="12532" checksum="CA2560499256A01A" modified="2018-07-18" version="1">MQILEYIDAIIRDRLSCCPAVLKISDLEPIFGDEVPTIRARIRRGSFPVTVRQEDGGRQYVLLADVIRFLATGERQPQVIPGMRTTATSAPKAGRRGRPTKAEQVAGVRRAKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYP1</accession>
    <name>A0A2S9GYP1_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Sulfate adenylyltransferase subunit 2</fullName>
            <ecNumber evidence="2">2.7.7.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">ATP-sulfurylase small subunit</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Sulfate adenylate transferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_2561</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PAPS reductase family. CysD subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.4" evidence="2"/>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92831">
        <property type="protein sequence ID" value="PRC92831"/>
        <property type="gene ID" value="S2091_2561"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004781">
        <property type="term" value="F:sulfate adenylyltransferase (ATP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019419">
        <property type="term" value="P:sulfate reduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01713">
        <property type="entry name" value="PAPS_reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002500">
        <property type="entry name" value="PAPS_reduct"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011784">
        <property type="entry name" value="SO4_adenylTrfase_ssu"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01507">
        <property type="entry name" value="PAPS_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002936">
        <property type="entry name" value="CysDAde_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02039">
        <property type="entry name" value="CysD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PAPS_reduct" evidence="7">
        <location>
            <begin position="36"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="286"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="290"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00030256"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00031812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC92831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="309" mass="35025" checksum="9F8C4D2F16FE61BB" modified="2018-07-18" version="1">MNAPQQFIDAASNRHLDWLESEAIHIMREVAAECSNPVLLFSGGKDSVVMLRLAEKAFRPGSFPFPLMHIDTGHNFDEVITFRDQRAAELGERLIVRSVEDSIKRGTVRLRNPATDSRNAAQAVTLLEAIEEFKFDACIGGARRDEEKARAKERIFSFRDEFGQWNPKAQRPELWDLYNTCVHSGQNIRVFPISNWTELDVWQYIEREKLALPPIYFAHERQVIPRNGLLVPLTDLTPAKEGEQVVTQVVRFRTVGDISCTCPVASDAATVAEIIAETAITQITERGATRMDDQTSEASMEKRKKEGYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYR9</accession>
    <name>A0A2S9GYR9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">ADP-ribose pyrophosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_2289</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the Nudix hydrolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92872">
        <property type="protein sequence ID" value="PRC92872"/>
        <property type="gene ID" value="S2091_2289"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020476">
        <property type="entry name" value="Nudix_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029401">
        <property type="entry name" value="Nudix_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14803">
        <property type="entry name" value="Nudix_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00502">
        <property type="entry name" value="NUDIXFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="3">
        <location>
            <begin position="37"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC92872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="186" mass="21235" checksum="207E22CB8DEE3979" modified="2018-07-18" version="1">MKFCSECAHPVSLKIPPEDNRLRFVCDHCNTIHYQNPKMVVGSIPVWEQSGETKVLLCRRAIEPRYGYWTLPAGFMENGETTSQAAMRETLEESGANIELHELFSLLNVPHVDQVHLFYRATLLDLNYSAGTESLEVALFSESEVPWDEIAFPTIFHTLKFFFSAPHANTPLSLHCHDILKPRTFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYW9</accession>
    <name>A0A2S9GYW9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2566</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92836">
        <property type="protein sequence ID" value="PRC92836"/>
        <property type="gene ID" value="S2091_2566"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08413">
        <property type="entry name" value="PBP2_CysB_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037423">
        <property type="entry name" value="CysB_PBP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="313" mass="34957" checksum="852D8FC7F8E00A24" modified="2018-07-18" version="1">MNLHQLRFVREAVRQNFNLTEAAKALFTSQPGVSKAIIELEEELGVDIFTRHGKRIRGLTEPGRSVLKSVELIMQEIEGLKQIGREFAAQDSGSLTIATTHTQARYALPPVVQAFMQKYPKVRLSLLQGNPKQVAEMVQRDQADLAIATESIAGIDGLITMPCYQWEHVVVVPLDHPLLKLKVISLEEIANYPLITYDSAFAGRNKIDHAFALRQIKPDILLEAIDADVIKTYVELGMGVGIIAGMAFDAERDKNLRSIPVGNLFGMNISRIALKQGAYLRSYVYTFIELLAPTLNRKLIDQVLQGTKDNYEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZ14</accession>
    <name>A0A2S9GZ14_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2367</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92950">
        <property type="protein sequence ID" value="PRC92950"/>
        <property type="gene ID" value="S2091_2367"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00885">
        <property type="entry name" value="cinA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.980.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036425">
        <property type="entry name" value="MoaB/Mog-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001453">
        <property type="entry name" value="MoaB/Mog_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00994">
        <property type="entry name" value="MoCF_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00852">
        <property type="entry name" value="MoCF_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53218">
        <property type="entry name" value="SSF53218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MoCF_biosynth" evidence="1">
        <location>
            <begin position="4"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="261" mass="29009" checksum="5E4022FFF9D53F22" modified="2018-07-18" version="1">MAIGLIIIGDEILSGKRADKHFSKVVELLSARGLQLGWTEIIGDDPERITATLQRTMATSDIVFCCGGIGATPDDHTRQCAAAALGVDLELHPEAKTLIQQRITQTLQEAGKPVDLNTPDLLHRLKMGEFPKGSSIIPNSYNLIPGFFKASHYFVPGFPVMAEPMLTWVLDTHYSHLFHQHERAEKSVLIFEIAESTLTPLMEQLEIDFPLIKVFSLPSVGNHQIRRHIELGVKGQPTQVEQAFAVLEQELELRNAEYVPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZ82</accession>
    <name>A0A2S9GZ82_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 4">30S ribosomal protein S1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_2425</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the bacterial ribosomal protein bS1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC93008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93008">
        <property type="protein sequence ID" value="PRC93008"/>
        <property type="gene ID" value="S2091_2425"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035104">
        <property type="entry name" value="Ribosomal_protein_S1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000110">
        <property type="entry name" value="Ribosomal_S1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022967">
        <property type="entry name" value="S1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10724:SF7">
        <property type="entry name" value="PTHR10724:SF7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00575">
        <property type="entry name" value="S1"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002111">
        <property type="entry name" value="RpsA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00681">
        <property type="entry name" value="RIBOSOMALS1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00717">
        <property type="entry name" value="rpsA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="S1 motif" evidence="5">
        <location>
            <begin position="28"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="domain" description="S1 motif" evidence="5">
        <location>
            <begin position="112"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="domain" description="S1 motif" evidence="5">
        <location>
            <begin position="199"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="domain" description="S1 motif" evidence="5">
        <location>
            <begin position="284"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="domain" description="S1 motif" evidence="5">
        <location>
            <begin position="371"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="domain" description="S1 motif" evidence="5">
        <location>
            <begin position="458"/>
            <end position="527"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR002111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC93008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="567" mass="62084" checksum="46595AEADCF32985" modified="2018-07-18" version="1">MSQDYATGTDSFAALFEESLSRQDMRSGEVISAEVVRIDHNFVIVNAGLKSEAFIPLEEFKNDQGELEVVVGDFVSVAIDSLENGFGDTILSRDKAKRLASWLALEKALESGEIVIGTVNGKVKGGLTVLTNGIRAFLPGSLVDTRPVKDTTPYEGKTMEFKVIKLDRKRNNVVLSRRAVVEASMGEERAKLMETLREGTVVTGVVKNITDYGAFVDLGGIDGLLHITDLAWRRVRHPSEVLTVGQEVTAKVLKFDQEKNRVSLGVKQLGDDPWTGLSRRYPQHTRLFGKVTNLTDYGAFVEVEQGIEGLVHVSEMDWTNKNVAPNKVVQLGDEVEVMVLEIDEERRRISLGMKQCKANPWDDFAVTHKKGDKVRGAIKSITDFGVFIGLSGNIDGLVHLSDLSWTETGEEAVRRFKKGDELEAIVLAIDVERERVSLGVKQLEGDPFNNYCAMNDKGAVVVGTVKSVEPKGAVIQLSEEVEGYLRASEISRDRVEDAGTHLKVGDSVEAMVLNIDRKARSIQLSIKAKDNVDTADAMQKMTATDSSAASGTTSLGALLKAKLDSKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZ89</accession>
    <name>A0A2S9GZ89_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Prolyl oligopeptidase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2130</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93044">
        <property type="protein sequence ID" value="PRC93044"/>
        <property type="gene ID" value="S2091_2130"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015592439" evidence="1">
        <location>
            <begin position="23"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S9" evidence="2">
        <location>
            <begin position="450"/>
            <end position="661"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="664" mass="74651" checksum="BA7F68DF9333B1C2" modified="2018-07-18" version="1">MNKHPLVTFLCALILIPSCHLALSADSLPSVESFFKDPEIRQAILSPNGHSIAILSKLPDGRQVIAVRDTSDLQKVTVPVTATDDKITSFNWVNENRISFTLMSTRLEFIGNLDLFAVNLDGSNRTHLISGNWKHKLQNTGSNIIEKTLTADYSYFGSTHDGSDDIIVSKITYNHFEVLSHYLFRLDTKTRSLTALHKGKQPGNVYYWELDANDVPRIALSKLEGQCITSYWAPDSESFTEIAHADCYNDKRFTPLFFEASESVYGRASYKGHDALFKYDLKKMQMASEPFLSIDGFDFIGWPETDLVAKKVLGIHYDGDAKATVWLDPHFKEIQKKVDDILTQTSNTVRCGSDCLNSPAVLVMATSDRQPKQYFLYTTATGAMIRIGSAYPNINPDQMGTRDFYHYQARDGRSIPVYVTLPPGNVTAPMPTVVLVHGGPNVRGSSWEWEQDAQFLASRGYVVIQPEFRGSTGFGFDHFKAGWKQWGLTMQDDLADAAKWAAQKGWADSKRTAIMGASYGGYATLMGLIKNPEIFRCGVEWAGVTDINMMFDRAESDASQENLNYSMKTLIGDQSVDAEMFKENSPLNHADKLTQPLLIAHGVQDHRVPLVQATEFRDAVKKTNKNVEWIVYTDEGHGWIHEENNIDFWKHVEVFLDKNLKSVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZ97</accession>
    <name>A0A2S9GZ97_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 14">Inosine-5'-monophosphate dehydrogenase</fullName>
            <shortName evidence="7">IMP dehydrogenase</shortName>
            <shortName evidence="7">IMPD</shortName>
            <shortName evidence="7">IMPDH</shortName>
            <ecNumber evidence="7 14">1.1.1.205</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">guaB</name>
        <name evidence="16" type="ORF">S2091_2145</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7 14">
            <text>H2O + IMP + NAD(+) = H(+) + NADH + XMP</text>
            <dbReference type="Rhea" id="RHEA:11708"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57464"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <dbReference type="EC" id="1.1.1.205"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
    </comment>
    <comment type="activity regulation">
        <text evidence="7">Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.</text>
    </comment>
    <comment type="pathway">
        <text evidence="7 14">Purine metabolism; XMP biosynthesis via de novo pathway; XMP from IMP: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7 13">Belongs to the IMPDH/GMPR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.205" evidence="7 14"/>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93059">
        <property type="protein sequence ID" value="PRC93059"/>
        <property type="gene ID" value="S2091_2145"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00601">
        <property type="reaction ID" value="UER00295"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003938">
        <property type="term" value="F:IMP dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006177">
        <property type="term" value="P:GMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00381">
        <property type="entry name" value="IMPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01964">
        <property type="entry name" value="IMPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005990">
        <property type="entry name" value="IMP_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015875">
        <property type="entry name" value="IMP_DH/GMP_Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001093">
        <property type="entry name" value="IMP_DH_GMPRt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11911">
        <property type="entry name" value="PTHR11911"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00478">
        <property type="entry name" value="IMPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000130">
        <property type="entry name" value="IMPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01302">
        <property type="entry name" value="IMP_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00487">
        <property type="entry name" value="IMP_DH_GMP_RED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 12" id="KW-0129">CBS domain</keyword>
    <keyword evidence="3 7 14" id="KW-0332">GMP biosynthesis</keyword>
    <keyword evidence="2 7 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 10 14" id="KW-0520">NAD</keyword>
    <keyword evidence="5 7 13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4 7 11" id="KW-0630">Potassium</keyword>
    <keyword evidence="7 14" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBS" evidence="15">
        <location>
            <begin position="92"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="15">
        <location>
            <begin position="151"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="IMP binding" evidence="7 9">
        <location>
            <begin position="336"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="IMP binding" evidence="7 9">
        <location>
            <begin position="359"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="region of interest" description="IMP binding" evidence="7 9">
        <location>
            <begin position="383"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="active site" description="Thioimidate intermediate" evidence="7 8">
        <location>
            <position position="303"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7 8">
        <location>
            <position position="399"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="246"/>
            <end position="248"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="246"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 10">
        <location>
            <begin position="296"/>
            <end position="298"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 11">
        <location>
            <position position="298"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 11">
        <location>
            <position position="300"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 9">
        <location>
            <position position="301"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 11">
        <location>
            <position position="303"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 9">
        <location>
            <position position="414"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="468"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
            <note>ligand shared between two tetrameric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="469"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
            <note>ligand shared between two tetrameric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="470"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
            <note>ligand shared between two tetrameric partners</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000130-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000130-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000130-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000130-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU003927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU003928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="PRC93059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="486" mass="51934" checksum="B85E5AB7BB9E224E" modified="2018-07-18" version="1">MRLLQKALTFDDVLLVPAYSDILPKETSLATRLTRNITLNIPLLSAAMDTVTEARLAIAMAQEGGIGIIHKNFTAKEQASEVAKVKRFESGVLRDPITIPPDMKIRDVIALSQQHGISGFPVVEGKVVVGIITNRDLRFERELDAKVRDKMTPREKLVYVDENADVVEAKRLMNKHRLERVLVVNAGFELHGLITVKDIQKSTEHPFASKDTHGKLRVGAAVGVGPDNDERIDLLVKAGVDVLVVDTAHGHSKGVLDRIRWIKTNYPQVDVIGGNIATAAAALAMVEHGADGVKVGIGPGSICTTRIVAGVGVPQISAISNVANALKGTGVPCIADGGVRYSGDVSKALAAGASTVMMGSMFAGTEEAPGEVILFQGRSYKSYRGMGSLGAMAAGSADRYFQEADASTEKMVPEGIEGRVAYKGSVLAILFQLVGGVKQSMGYCGCATIEDLHNKAEFVEITSAGMRESHVHDVQITKEAPNYRAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZD1</accession>
    <name>A0A2S9GZD1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2149</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93063">
        <property type="protein sequence ID" value="PRC93063"/>
        <property type="gene ID" value="S2091_2149"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010260">
        <property type="entry name" value="AlpA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05930">
        <property type="entry name" value="Phage_AlpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="76" mass="8629" checksum="4E5DB62A1DBD6E74" modified="2018-07-18" version="1">MNTTTLINRKKLLAMIPLSDRAIFDMEKRGEFPRRIALTSRNVAWDLGEIQAWIVERKSSGDQARRPGLTQMVASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZK7</accession>
    <name>A0A2S9GZK7_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Amidophosphoribosyltransferase</fullName>
            <shortName evidence="5">ATase</shortName>
            <ecNumber evidence="5">2.4.2.14</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Glutamine phosphoribosylpyrophosphate amidotransferase</fullName>
            <shortName evidence="5">GPATase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">purF</name>
        <name evidence="10" type="ORF">S2091_2250</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>5-phospho-beta-D-ribosylamine + diphosphate + L-glutamate = 5-phospho-alpha-D-ribose 1-diphosphate + H2O + L-glutamine</text>
            <dbReference type="Rhea" id="RHEA:14905"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:58681"/>
            <dbReference type="EC" id="2.4.2.14"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5 8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="5 8">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 5 6">Purine metabolism; IMP biosynthesis via de novo pathway; N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-alpha-D-ribose 1-diphosphate: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 5 6">In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.14" evidence="5"/>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93164">
        <property type="protein sequence ID" value="PRC93164"/>
        <property type="gene ID" value="S2091_2250"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00124"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004044">
        <property type="term" value="F:amidophosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009113">
        <property type="term" value="P:purine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00715">
        <property type="entry name" value="GPATase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01931">
        <property type="entry name" value="PurF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRibTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005854">
        <property type="entry name" value="PurF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035584">
        <property type="entry name" value="PurF_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00156">
        <property type="entry name" value="Pribosyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000485">
        <property type="entry name" value="Amd_phspho_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01134">
        <property type="entry name" value="purF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="5 6 10" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5 8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 5 6" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="9">
        <location>
            <begin position="2"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="5 7">
        <location>
            <position position="2"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5 8">
        <location>
            <position position="304"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 8">
        <location>
            <position position="366"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 8">
        <location>
            <position position="367"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR000485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000485-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000485-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC93164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="505" mass="55590" checksum="F465AC0CDC6E922B" modified="2018-07-18" version="1">MCGIVGVVSNSMVNQVIYDALLLLQHRGQDAAGIATNHSSSFAMHKANGLVRDVFRTRNMRSLPGNVGIGHVRYPTAGSTSEEEAQPFYVNAPFGITLAHNGNLTNAEQLKIELFKNDRRHINTDSDSEVLLNVLAHEIQQATSSYSLDPATLFGAIARLHNRVRGAYAVVAQIAGFGLLAFRDPYGIRPLCLGVLETDKGDEYMIASESVALEGLGFRFVRDVEPGEAIFIDEDHKLYSQQCAENPSLNPCAFEYVYLARPDSIIDGASVYATRLKMGEYLAEQVRHHMASGAIDVVMPIPDTSRPSAMQLALKLNLDYREGFIKNRYIGRTFIMPGNVSRRKSVRQKLNAIGSEFKGKSVLLVDDSIVRGTTSREIVQMARESGATRVIFASAAPPVKFPNVYGIDMPTRQELIAYGRSNEEICREITADALVYQEVSAMRRAIADVNPRLTSLEASCFDGEYITGDITRDYLDRLEAARNSPNSMTEDGVPSQLNLNLAKGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZM0</accession>
    <name>A0A2S9GZM0_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">3-isopropylmalate dehydratase large subunit</fullName>
            <ecNumber evidence="12">4.2.1.33</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Alpha-IPM isomerase</fullName>
            <shortName evidence="12">IPMI</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">Isopropylmalate isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">leuC</name>
        <name evidence="14" type="ORF">S2091_2236</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 12">Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>(2R,3S)-3-isopropylmalate = (2S)-2-isopropylmalate</text>
            <dbReference type="Rhea" id="RHEA:32287"/>
            <dbReference type="ChEBI" id="CHEBI:1178"/>
            <dbReference type="ChEBI" id="CHEBI:35121"/>
            <dbReference type="EC" id="4.2.1.33"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="12">Binds 1 [4Fe-4S] cluster per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 12">Amino-acid biosynthesis; L-leucine biosynthesis; L-leucine from 3-methyl-2-oxobutanoate: step 2/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12">Heterodimer of LeuC and LeuD.</text>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.33" evidence="12"/>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93150">
        <property type="protein sequence ID" value="PRC93150"/>
        <property type="gene ID" value="S2091_2236"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00048">
        <property type="reaction ID" value="UER00071"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003861">
        <property type="term" value="F:3-isopropylmalate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009098">
        <property type="term" value="P:leucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01583">
        <property type="entry name" value="IPMI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.499.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01026">
        <property type="entry name" value="LeuC_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004430">
        <property type="entry name" value="3-IsopropMal_deHydase_lsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015931">
        <property type="entry name" value="Acnase/IPM_dHydase_lsu_aba_1/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001030">
        <property type="entry name" value="Acoase/IPM_deHydtase_lsu_aba"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018136">
        <property type="entry name" value="Aconitase_4Fe-4S_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036008">
        <property type="entry name" value="Aconitase_4Fe-4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033941">
        <property type="entry name" value="IPMI_cat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00330">
        <property type="entry name" value="Aconitase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00415">
        <property type="entry name" value="ACONITASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53732">
        <property type="entry name" value="SSF53732"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00170">
        <property type="entry name" value="leuC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00450">
        <property type="entry name" value="ACONITASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01244">
        <property type="entry name" value="ACONITASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 12" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="6 12" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="11 12" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="8 12" id="KW-0408">Iron</keyword>
    <keyword evidence="9 12" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4 12" id="KW-0432">Leucine biosynthesis</keyword>
    <keyword evidence="10 12" id="KW-0456">Lyase</keyword>
    <keyword evidence="7 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aconitase" evidence="13">
        <location>
            <begin position="30"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="370"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="431"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="434"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="PRC93150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="491" mass="53038" checksum="35D29773F5BA2A51" modified="2018-07-18" version="1">MIAARNYGIIKRSNKYVNQVARIMLKTLYDKLWESHAVHAEPDGTTILYIDRHLLHEVTSPQAFDGLRLTGRAPWRVSANLVVADHNVPTTNRINGIADPTSRLQVETLDANTKQYGLTYFGMNDKRQGIVHVIGPEQGATLPGMTVVCGDSHTSTHGAFGCLAHGIGTSEVEHVLATQTLITQKSKAMLVQVDGALPLGVTAKDVVLAIIGKIGTAGGTGYAIEFAGSAIRSLSMEGRMTVCNMAIEAGARAGMIAVDDTTIDYVKGRPYSPVGPHWEQAVSYWRTLHTDAGAPFDLVIHLNAAEIKPQVTWGTSPEMVLSIDGRIPDPDQEKDATKRDAIEKALAYMALKPNTAITDIRIDKVFIGSCTNSRIEDLRAAASVVRGKYRASNVKLAMVVPGSGLVKEQAEREGLDRIFKDAGFEWREPGCSMCLAMNADRLEPGERCASTSNRNFEGRQGQGGRTHLVSPAMAAAAGIAGHFVDVRTLRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZQ4</accession>
    <name>A0A2S9GZQ4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">CBS-domain-containing membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_2269</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93183">
        <property type="protein sequence ID" value="PRC93183"/>
        <property type="gene ID" value="S2091_2269"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007065">
        <property type="entry name" value="HPP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04982">
        <property type="entry name" value="HPP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0129">CBS domain</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="24"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="51"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="77"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="143"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="3">
        <location>
            <begin position="245"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="3">
        <location>
            <begin position="329"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC93183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="389" mass="42818" checksum="2BCBD9D5EB6F2912" modified="2018-07-18" version="1">MNKTIHWLHGFIPKPTAINNLERLRACSGALFGILLTGLVARWLYGATAPLPLLVAPMGASAVLLFALPSSPLAQPWALIGGNLVSAALGVTCAQWINDPMLAASLAVAASIGAMMVLRCVHPPSGAVALTAVLGGPLIHAEGYRFVLAPIGINSLLLLAVALIFNNLTKHVYPHRVIEHGNTHRTADRQSNERLGFTSTDLDYVLTQYNQILDVSRDDLESLLIQTEMHAYRRRFGEITCADIMSRDVISVEFSTDLQHAWELLHRHNIKALPVIDPARRVIGIVTLVDFMQHAGLDRYQNFATKMRQFLRHVGRAHSEQPEVIGQIMTPVVHTAFDSMHITELVDLFSHKGLRHIPIINAEHHLVGMVTNSDLVAGLYRGRLGDMDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZS2</accession>
    <name>A0A2S9GZS2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="10">TonB-siderophor: TonB-dependent siderophore receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">S2091_1973</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93235">
        <property type="protein sequence ID" value="PRC93235"/>
        <property type="gene ID" value="S2091_1973"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015344">
        <property type="term" value="F:siderophore uptake transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0038023">
        <property type="term" value="F:signaling receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039423">
        <property type="entry name" value="TonB-dep_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010105">
        <property type="entry name" value="TonB_sidphr_rcpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32552">
        <property type="entry name" value="PTHR32552"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01783">
        <property type="entry name" value="TonB-siderophor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="3 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 10" id="KW-0675">Receptor</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="2 6" id="KW-0798">TonB box</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015565761" evidence="7">
        <location>
            <begin position="26"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="domain" description="Plug" evidence="9">
        <location>
            <begin position="78"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="8">
        <location>
            <begin position="281"/>
            <end position="741"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC93235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="743" mass="80342" checksum="C847F4714D31F90B" modified="2018-07-18" version="1">MSIKKTKPALLVALALQQLSSPVFAQTSAPATTIARDTSSNQLADGQPLPEIIVKGQRANSDYAPAVTHVGAKTEQALRDVPQTVNVVNKDLMDAQGATSLADALRNVPGITIGGAEGGQIGNNINLRGFTARTDIYMDGFRDRGQYYRDLFDLEQVEVLQGPSSMLFGRGSTGGVINQETKQAKLGNFATVSGTVGSDGRARTTLDDNTQLSDTSALRVNVFAQNLETTRDVMSNKDFGVAPTLRLGIGQPTEITISALLQHNNDMPDYGVESLNGHPVTASSSTFYGLASDQTNQDIAMLNGVVKHTFNDTFVLRNQTQFNRYTTDAQESAAHALSTTNTAAGVITPPAFGNYNPAKLWVELQSHDRNIVDTSVDNQTDLIAKFVTGTIKHEMIVGAEFGHDTYSNQTLSRTGAGMPAGYVGFVSLMNPSDATPATVTTTNGNLAQSTANTVGIYVNDTISLNEHWKVVTGVRWDRFDAQINNSISLPAHATQDASFTSLREGLIYQPTEEQSYYASYGTSFDPLLEQMTLTNGQQSLPPTNTRSYELGGKWDLLNDKLMVSFAAFNEKQNNVYSVSNGEYQASGNWLIKGATLGAVGHITDQLQISSGYMHLDPKVIDTVDGTAGSTPGNTPKNTFNVWTTYDINKTWQVGGGVFYMSDRFVADSGITSTLPQGNVDRVSVPSYTRWDATVAYHQPKYDIRLNLLNLTNKQYYDALIQSDGGRAVPGIGRTALLTGTYHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZS8</accession>
    <name>A0A2S9GZS8_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">HTH-type transcriptional regulator MetR</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_1972</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93234">
        <property type="protein sequence ID" value="PRC93234"/>
        <property type="gene ID" value="S2091_1972"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009086">
        <property type="term" value="P:methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08441">
        <property type="entry name" value="PBP2_MetR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037406">
        <property type="entry name" value="MetR_PBP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="7">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC93234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="295" mass="33384" checksum="814DB617BAB9A74E" modified="2018-07-18" version="1">MLERIHLTVIREVDRQGSLTAAADVLCLTQSALSHTIKKIEAQLGTPIWTREGRSLRLTQAGHYLLVLANRLLPQLEHAEQIMQQYALGQRGTLRIGMECHPCYQWLLKVVAPYLTSWPDVDVDVKQKFQFGGIKALLGYEIDLLVTPDPLYQPGLLFEPVFDYEQVLVVSQTHHLAALTFVTPQQLAEETLITYPVAIERLDIYQQFFLPANCTPKQHKTIETTDIMLQMVASGRGVAALPRWLVAEYADKMGIRPVRLGQDGIAKQIFLGVRETDGDINYLKAFVELARQHKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZZ2</accession>
    <name>A0A2S9GZZ2_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Cell shape-determining protein MreB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">mreB</name>
        <name evidence="3" type="ORF">S2091_2008</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Forms polymers.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="2">Membrane-associated.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the FtsA/MreB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93270">
        <property type="protein sequence ID" value="PRC93270"/>
        <property type="gene ID" value="S2091_2008"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000902">
        <property type="term" value="P:cell morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd10225">
        <property type="entry name" value="MreB_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02207">
        <property type="entry name" value="MreB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004753">
        <property type="entry name" value="MreB"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01652">
        <property type="entry name" value="SHAPEPROTEIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00904">
        <property type="entry name" value="mreB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0133">Cell shape</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="19"/>
            <end position="21"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="169"/>
            <end position="171"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="217"/>
            <end position="220"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="297"/>
            <end position="300"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="347" mass="37109" checksum="EA1BCC864A664E69" modified="2018-07-18" version="1">MFGFFRSYFSNDLAIDLGTANTLIYVRGQGIVLDEPSVVAIRQEGGPNGKKTIQAVGKEAKQMLGKVPGNIEAIRPMKDGVIADFTVTEQMLKQFIRMVHDTKFFKPSPRIIICVPCGSTQVERRAIRESALGAGASQVYLIEEPMAAAIGAGLPVSEATGSMVVDIGGGTTEVGIISLGGMVYKGSIRVGGDKFDEAIVNYIRRNYGMLIGEQTAEAIKKTIGSAFPGSEVKEMEVKGRNLSEGIPRSFTISSNEILEALTDPLNNIVSAVKNALEQTPPELGADIAEKGMMLTGGGALLRDLDRLLMEETGLPVIVAEDPLTCVVRGSGMALDRIEKLGSMFSYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H024</accession>
    <name>A0A2S9H024_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Adenosylmethionine-8-amino-7-oxononanoate aminotransferase</fullName>
            <ecNumber evidence="4">2.6.1.62</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">7,8-diamino-pelargonic acid aminotransferase</fullName>
            <shortName evidence="4">DAPA AT</shortName>
            <shortName evidence="4">DAPA aminotransferase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">7,8-diaminononanoate synthase</fullName>
            <shortName evidence="4">DANS</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Diaminopelargonic acid synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">bioA</name>
        <name evidence="6" type="ORF">S2091_2072</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>(8S)-8-amino-7-oxononanoate + S-adenosyl-L-methionine = (7R,8S)-7,8-diammoniononanoate + S-adenosyl-4-methylsulfanyl-2-oxobutanoate</text>
            <dbReference type="Rhea" id="RHEA:16861"/>
            <dbReference type="ChEBI" id="CHEBI:16490"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:149468"/>
            <dbReference type="ChEBI" id="CHEBI:149469"/>
            <dbReference type="EC" id="2.6.1.62"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 4">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Cofactor biosynthesis; biotin biosynthesis; 7,8-diaminononanoate from 8-amino-7-oxononanoate (SAM route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.62" evidence="4"/>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93334">
        <property type="protein sequence ID" value="PRC93334"/>
        <property type="gene ID" value="S2091_2072"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00078">
        <property type="reaction ID" value="UER00160"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004015">
        <property type="term" value="F:adenosylmethionine-8-amino-7-oxononanoate transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009102">
        <property type="term" value="P:biotin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00610">
        <property type="entry name" value="OAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00834">
        <property type="entry name" value="BioA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005815">
        <property type="entry name" value="BioA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000521">
        <property type="entry name" value="Transaminase_4ab_Lys_Orn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00508">
        <property type="entry name" value="bioA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00600">
        <property type="entry name" value="AA_TRANSFER_CLASS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="4" id="KW-0093">Biotin biosynthesis</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 4 5" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Pyridoxal phosphate binding" evidence="4">
        <location>
            <begin position="89"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Pyridoxal phosphate binding" evidence="4">
        <location>
            <begin position="292"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="29"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="122"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="228"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="257"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="291"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="377"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM" evidence="4">
        <location>
            <position position="5"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="4">
        <location>
            <position position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC93334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="413" mass="45347" checksum="A5878C576E2CCF35" modified="2018-07-18" version="1">MPLVPISHGRGAWLFDADGNRYLDGISSWWVNLFGHANPRINAALKDQLDKLEHVMLAGFTHEPVIRLSEQLSEKTGHALGHCFFASDGASAVEIALKMSFHSWSNLGLGDKREFVCLKGSYHGETIGALAVTDVALFRDAYGPLIGSAHVVMSPDARQAIDGETAQDVARRAIAEVEKLFEQRSTKIAAMIVEPLVQCATGFAMHDPLYLQLLRALCDKYQVHLIADEIAVGCGRTGTFFACEQAAIWPDFMCLSKGISGGYLPLSLVMTTDKVYQAFYHQDVKRGFLHSHSYTGNPLACRAALATLEIFEQDNVLENNVERAAKITAALAPLALHAKVKNFRQRGMIWAFDAVDVSAGFSSRFFKAALTQELLLRPIGNTVYLMPPYILNDEECALLGQRTLSVFEQVAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H049</accession>
    <name>A0A2S9H049_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Hydroxymethylglutaryl-CoA lyase</fullName>
            <ecNumber evidence="4">4.1.3.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_2066</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(3S)-hydroxy-3-methylglutaryl-CoA = acetoacetate + acetyl-CoA</text>
            <dbReference type="Rhea" id="RHEA:24404"/>
            <dbReference type="ChEBI" id="CHEBI:13705"/>
            <dbReference type="ChEBI" id="CHEBI:43074"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="EC" id="4.1.3.4"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Metabolic intermediate metabolism; (S)-3-hydroxy-3-methylglutaryl-CoA degradation; acetoacetate from (S)-3-hydroxy-3-methylglutaryl-CoA: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the HMG-CoA lyase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.3.4" evidence="4"/>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93328">
        <property type="protein sequence ID" value="PRC93328"/>
        <property type="gene ID" value="S2091_2066"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00896">
        <property type="reaction ID" value="UER00863"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004419">
        <property type="term" value="F:hydroxymethylglutaryl-CoA lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000138">
        <property type="entry name" value="HMG_CoA_lyase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043594">
        <property type="entry name" value="HMGL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000891">
        <property type="entry name" value="PYR_CT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42738">
        <property type="entry name" value="PTHR42738"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00682">
        <property type="entry name" value="HMGL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01062">
        <property type="entry name" value="HMG_COA_LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50991">
        <property type="entry name" value="PYR_CT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyruvate carboxyltransferase" evidence="6">
        <location>
            <begin position="14"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC93328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="309" mass="32446" checksum="42DA49E3F0B07D4E" modified="2018-07-18" version="1">MNSYATSATLPSSVKIVEVGPRDGLQNEATTISAEVKIELVNRLSAAGFINIESASFVSPKWVPQMATSTEVMAGIERKAGVIYSVLTPNMKGFEAAIAAGADEVVIFGSASEAFSQKNINCSIAESIERFREVAVAAKANNKRLRGSLSCSFGCPYQGAVSPEAVADVVQRLRDLGCDEIDIADTIGVGTARQVQTVMQRVMREFPVSGLSGHFHDTYGQALANIYASLEVGISIFHSSVAGLGGCPYAKGATGNVATEDVLFLMQGLGIHTGIDLDKTVDAGQFISQHLGRKAVSRAGNALAAKRVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0E2</accession>
    <name>A0A2S9H0E2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1841</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93454">
        <property type="protein sequence ID" value="PRC93454"/>
        <property type="gene ID" value="S2091_1841"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045538">
        <property type="entry name" value="CIS_TMP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19268">
        <property type="entry name" value="CIS_TMP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1450"/>
            <end position="1469"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="2520" mass="284973" checksum="4AFB9B2DE033C636" modified="2018-07-18" version="1">MRTHHSIHELIFDLSFASAQADGSAWSEWIKYSLLPVIDEVLDQHATTAKLAPQRTKRIKKIELDLGTVFEDETGTEIARRIHAQLSAALDYQLQEHTAAELSGEHKAQALHDLHYFLKTGAISWEKSNKTRFAHKKLLHDALNQQNHAQLLQEITESPRQLNRLVQQYDTGELFQIANRMLASWTKELSETVLDWISLELLAQGESERNHAEFWMYLLPILRHTNVDFTQIVHPWLKQKQTTVEVATTNYRRLLADKSGLSNATWLALSNALEHYEAQMRSTSASAFVVGAVNEYKSGSVDSQYNEAQPASNQSAQDELHRSYRRRLQAARIGRDSNQAIEESESEEAQQIFTIEERTHITQSLAQGDFAKLEPHWHRLLLLAPHFVRDQHGEAWSIWLKNFDHAHCLDLIAVLQPQCAWFILQTFQANIASYSRATLDQVITYAISVKPEQLQVNELTQFTLEHVTSGNINSKKTADQLTQARHALKTANIALLAPFWRQLISQHSDLIQQLLPHYLEVWLANFPIRYLQDLVILLQTEASTAWAPQRYYAEDSNATMPIQRGYRLLLQAPVQSLSREEFIQRITQEVREHPSDAATLAAINTSVLPEQSAQLVTDKINRDDIIGMATAQIRTALHGPLPLNAVDILQNSPTTAKVQESRHAGQATAAEYTHQLNSSANEIASTNEAFRSAEVLKKISSKQNIAKQYIKADEQTAHEEHSHPATSQNQVMPLTAEQVLLVLQTANLAQLNGIWEQAVKKQPKLLIDCYRQLSSRESKILSDVFTMEQNLTLARLLHPHIAELLNELINNAGFITETASRLALNSKHGHSSLSTEFVQNLVIDISLNTLQTQLSAPSLIQNLARVMLGSDDLFQEFCEQLVKNGTSHPMPLLSTTLTRNFLLRGTNQHVSSDLLPGTPTDPSSSDRIAQSIKDYINTLLKNTNVAALNAVWNTIILSHATTLVSNFKQLDRQERLRLVQSLSKEKLLQLAQILQAQLTALIAELFDHAAFIVAAIQSMQVTNNNTRKAITVVTFEQNVLDACFCLEQNNLVELQATQFFTRVMQNAMGADVNSTMAALGQLRWSGTSIFRAKLPLTEVILVELRRAHMPMSEFKEIQALNKYTSAPTSTTSLTANSGLNPLLSSYRSWQQGKLQLAQLDLNVDELYQYLHWWMAQYEESNQQNFKSLLQSIRSAEQTCVVPLLFLQQVLETLRQQESIDIDALIAQTRALAQHQSEDNFVGEGEQALNSDDVFIEPMFEETPYRDDIKHYVDGINGASTVETNDQLSLSSQFYYFAKYIADILANQRPIQELPGILKHNAAYLSHISNAQLHQLIIAWVQSRSDEGVPSVFLTSLERYALRAGSMHMSTHNFLSTVLQNLVYEIAIDFEQLLKAENRATTNQQTFATSSNTVIDAKPVSNVEETTLANLPLLQAESFAALLSYIVKSQGSDSQKEPSPDTLGTNASVREDATLRSEDDDLIWLNIRSAFESPTLQLWLCEWIDTCIPRPYFVEQKAALHLLALDKQSPSATIVLILKAILMSFPKSLLNSCIDILQKRFGISLNLLSQLQGHQLAAPAHQQRYEACVSFFKNIPWERLEETTLAIQPLFQAENFADLLSNMLVNSSVDNQKESPLGALRANANVRENATLQSEDDDLIWPGIRIAFENPTLQFWLCEWIDTYTPRLRLGEQKATQHLLAFNQQSPSATIVLILKAMLMSFPKNILSSCVDILQKRFGISSNLLSQLQNYQLSFPEHQQRYEACVSFFKNIPWERWEEKTSPASSSDTPVSLLPINLRNALPNRLADAMLTARLDGLDLIWHEITTYHSDLLAQSQLHYLGRAELRARIIENNIPSKLNDMLKALSPSLAEFVEELNKEWSSIQSILSPHRSFEEFKQHTLRESFDLIFKQQLRHASRMEQASALLRAILEQRQLHSDVFFHNKMNELLYKINPSIAPQWHASLRLNLHLNTIKELAAENERVGSSTSSQTIFDTASDTTSDTTLIDADTVREVLFEELLQHELHEVFSAFETAESPLSLDAVFSDVQVSALYTHYLSEKAPEVNREFWQVYADELCELDERQKKTIADTAIATDSSSTFSTSVDTHENCRQRVLRQFVQSQATSTISTAKTTPSAVSYIELGKLDSTAQENRLTYCILLLQRDALLTAHEIIYGRHAFSLLLQEAPRSLQQLSTTLQKTEAIKRLSQLLGSVDLARLFEILVPNLAKHVHFLCATIQDAQAVELYGESGALLERSWRAIYRSEFSTPRPPTLRQFSLRLLNELNQELQPGAKFIDAELSLQRIEHQRQHQQKIDRKKRQHSALAEQAMRGKEMIALPKNQSKKADEEPLMSAAEESNIFNAGMVIVAPYIQRLFTILELSKDGAFVDKQAAERAVHLLQYIVTGEERTPEYLLSLNKLLCGIPGGVPIVAGIKMTDQEKEVIEQMLLGVINNWSAIGKTSIAGLRETFLAREGRLSFQEVAWQLKIAPSTFDMLLDRLPWSFATIKFPWMVEALHVTWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0H5</accession>
    <name>A0A2S9H0H5_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Coproporphyrinogen-III oxidase</fullName>
            <ecNumber evidence="8">1.3.98.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">S2091_1872</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Involved in the heme biosynthesis. Catalyzes the anaerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen III to yield the vinyl groups in protoporphyrinogen IX.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>coproporphyrinogen III + 2 S-adenosyl-L-methionine = 2 5'-deoxyadenosine + 2 CO2 + 2 L-methionine + protoporphyrinogen IX</text>
            <dbReference type="Rhea" id="RHEA:15425"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:57307"/>
            <dbReference type="ChEBI" id="CHEBI:57309"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="EC" id="1.3.98.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8 10">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="8 10">Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 8">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; protoporphyrinogen-IX from coproporphyrinogen-III (AdoMet route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 8">Belongs to the anaerobic coproporphyrinogen-III oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.98.3" evidence="8"/>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93485">
        <property type="protein sequence ID" value="PRC93485"/>
        <property type="gene ID" value="S2091_1872"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00251">
        <property type="reaction ID" value="UER00323"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051989">
        <property type="term" value="F:coproporphyrinogen dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004109">
        <property type="term" value="F:coproporphyrinogen oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006782">
        <property type="term" value="P:protoporphyrinogen IX biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004558">
        <property type="entry name" value="Coprogen_oxidase_HemN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034505">
        <property type="entry name" value="Coproporphyrinogen-III_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010723">
        <property type="entry name" value="HemN_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023404">
        <property type="entry name" value="rSAM_horseshoe"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13932">
        <property type="entry name" value="PTHR13932"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06969">
        <property type="entry name" value="HemN_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000167">
        <property type="entry name" value="HemN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00538">
        <property type="entry name" value="hemN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 10" id="KW-0408">Iron</keyword>
    <keyword evidence="8 10" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="8 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6 8" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 9" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="11">
        <location>
            <begin position="54"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="63"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="69"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="73"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="75"/>
            <end position="77"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="76"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="120"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="121"/>
            <end position="122"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="155"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="182"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="194"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="219"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="253"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="339"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR000167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000167-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000167-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PRC93485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="468" mass="52952" checksum="E5530C231C88E595" modified="2018-07-18" version="1">MQVSESRGVEFDAQLIRKLNKSGPRYTSYPTADRFVDSFGYRDYLQAAAALRTRGSRNPLSLYLHIPFCDTVCYYCACNKIVTKNHEKAATYLSYLKREIEMQGQLFAGMNQVEQLHLGGGTPTYFSDSQMGELLAHLRRWFQFAPDDVGEYSIEVDPRTVTPERVHSLRRQGFNRISLGVQDFDPEVQKAVNRIQSESETLAIIDAARDANFRSISIDLIYGLPKQNVMSMAQTLAKVVSARPDRIAIYNYAHLPHVFKPQRRILDSELPSAESKLDMLALCIRHLTNAGYVYIGMDHFALPTDDLAVAQRQGRLHRNFQGYSTHADSDLVSCGISAISAVAATYSQNVKTLDAYYEHLDNNELPIARGIKLNMDDALRRVIIQMLMCNFELSISSIEAAYPITFATYFTSELAALQTFADDGLLAIDDEWLSVTPKGRLLVRNICMVFDRYLATKQEQPLRYSKTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0L4</accession>
    <name>A0A2S9H0L4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative PEP-CTERM system TPR-repeat lipoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1912</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93525">
        <property type="protein sequence ID" value="PRC93525"/>
        <property type="gene ID" value="S2091_1912"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014266">
        <property type="entry name" value="PEP-CTERM_TPR_lipo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="16"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02917">
        <property type="entry name" value="PEP_TPR_lipo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="33"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="373"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="478"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="648"/>
            <end position="681"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="932" mass="102716" checksum="D24E6B9FA9728484" modified="2018-07-18" version="1">MSLNRIVQTSAKVLPVALLLIFGLTACNKFRSAEKFIADAKSYEQKGDHKAAVIQLKNALQKDPNNSSARLLLGTIYIETGEAASAENELRKAASLGVKKDQVLPLLAKSLLLQSQFKKVLSETDQATNLNADPDMLTMRGNALLGLRQYSEAKDAYELALKAQADYPAALIGLSKQAYFEKDIAGANKYADLATSKNSKSIEAWIFKGDLLRMQSQPDLALLAYGEALKLQADNSTALIEKANVEISMKKFAEAQADILAAKKANPGNLVAIYTQALLDFSQGKNKEALESLQQVQKSAPKYMPAILLTGAVQFALGSTKQSEVYLQKYLEGNPGSVYAQKMLAASQLKNGQADKALETLDATLKDDSIQDNQLFAIAGDAATRTRNYTKANEYFEKAIALAPENANYHSALAVSKLSMGDNDRAISELETATTLNNKSSSSSKSGVLLVMTYMHLQDFDKALTTIKALEKDQPENPMLKNLTGGIYLNKNDKANARANFEKALALQPTYFPASFNLASMDIREKKFDEAKKRIMSMLSKDNKNLQVNLALAGLAQLQGNKEETKKWLEKAHEEHPESLQAAQILITYYLGTQDKQKALTMAKNLQTSNPENRGYLNLLAQTQEMADDKQGAVASFTMLAALRPNSPDEQFRVAVAYISIGKETEAIDALKKTLRLDPKFLKAQIAMAGIQTKHGDFELALQFAQQVQKQSPKGPEGYVMEGDILMAKKKPELAVKAYETAYNLSKHGPMLVKLHYALVQNGKDKEADAKVLQWLKDNPTDLSTRLYLAIYWLGSQKSKLPAIEQFQIILKNDPNNLVALNNLAWAYDQEKNPQALQYAEKSYQIAAGNPQILDTYGWILVEKGEVARGLPMLQQAAKIIPAESEVRYHLAFALAKSGEKDKARKELEQITAGKDFPNMKEAKSLLVQMSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0V1</accession>
    <name>A0A2S9H0V1_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Probable potassium transport system protein kup</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">kup</name>
        <name evidence="12" type="ORF">S2091_1616</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Transport of potassium into the cell.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cell membrane</location>
            <topology evidence="11">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the HAK/KUP transporter (TC 2.A.72) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93615">
        <property type="protein sequence ID" value="PRC93615"/>
        <property type="gene ID" value="S2091_1616"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015079">
        <property type="term" value="F:potassium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01522">
        <property type="entry name" value="Kup"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003855">
        <property type="entry name" value="K+_transporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023051">
        <property type="entry name" value="K+_uptake_low_affin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30540">
        <property type="entry name" value="PTHR30540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02705">
        <property type="entry name" value="K_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 11" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9 11" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 11" id="KW-0630">Potassium</keyword>
    <keyword evidence="5 11" id="KW-0633">Potassium transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="21"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="59"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="112"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="150"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="180"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="220"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="256"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="296"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="343"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="374"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="403"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="434"/>
            <end position="451"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01522"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PRC93615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="634" mass="68340" checksum="1D971130D461C882" modified="2018-07-18" version="1">MSQAAPLAPAKTPLLINKQQAGITALGLSALGVVFGDIGTSPLYTLKTVLALSGGTPSAPVILGLLSLLLWTLIIVTSVKYVSFAMRIDNNGEGGILALMALLGIKKRKRPLVVAAGLLGAALIYGDGAITPAISVLSALEGLNIVFPAAKPYVLPATVVILLALFAIQPMGTERIGKAFGPVMAVWFLCIALLGIWGIIQHPSVLVAINPMYGVKFLMSNGLTSFLVLGGVFLCVTGAEALYADMGHFGARPIRLAWTAIVFPSLLLNYAGQAALVLSGAETADNIFYRLCPAPLLIPMVLLAAVATVIASQSIITGAFSMTRQAIQLGWLPRLQIKQTSEFGYGQIYVGTINWTLMIVTVGMALFFKSSDNMAAAYGIAVSLTMLMTSVLLFIAMREIWRWSLWASGAVAGVFLIIDGGFFAANLVKLLDGGYVPLLLAALVYSVMQVWHRGVAAVSKAINENVIPAAQFMADIEAQQISRVAGTAVFLTRTAEGTPPVMRWHVKRNQVLQQKIIAVNVVVETVPWISDAERFTMTELAPNFWRISARYGFMDRPDIPKLLQQPAFSSCELDLKAATYYLGLETVVVNEDAGLFKRWQGTLFAVMMRNSMHVTDFYRLPCDQVVEIGRRILI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0W2</accession>
    <name>A0A2S9H0W2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="10">TonB-hemlactrns: TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">S2091_1625</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93624">
        <property type="protein sequence ID" value="PRC93624"/>
        <property type="gene ID" value="S2091_1625"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015232">
        <property type="term" value="F:heme transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039426">
        <property type="entry name" value="BtuB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011276">
        <property type="entry name" value="TonB_haem/Hb_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010949">
        <property type="entry name" value="TonB_Hb/transfer/lactofer_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30069">
        <property type="entry name" value="PTHR30069"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01785">
        <property type="entry name" value="TonB-hemin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01786">
        <property type="entry name" value="TonB-hemlactrns"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="3 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 10" id="KW-0675">Receptor</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0798">TonB box</keyword>
    <feature type="domain" description="Plug" evidence="9">
        <location>
            <begin position="46"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="8">
        <location>
            <begin position="290"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="225"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC93624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="737" mass="80878" checksum="56AA4BCED69044AE" modified="2018-07-18" version="1">MAFLHQSSVAVAVTLALQRLANAEQLADPIPLDEITVTATRSASDVNKVAATVTVLPSEKLDTGLVHDIKDLERLDLGISIRQAPTRFGASFGSTGRAGNEGINIRGLEGNQILLQVDGIRLPNAYSFGPQSTGRGDYLDMDSLKTVEILRGSSSSLYGSDGLAGAVSFITKDPEDYFDSADKNTYFSVKNAFNSLDNSWGLTGTAALRNDQLQALLLLSHKQGNETKNMGDRDAPNFTRDQPNPQDKKSDYALAKLVFNIDAQQRIKLTAESLRRDSDTNVLTARLAPPPPASDNTLIVPPLRPNTVLDLQAADNLQRDRFSLNYIYEENNNPWWQTVDLNAYHQSSENQQASFETRNTAANRIRDNSYSQDTTGISAQFNSKLGQQQQLIYGADWSRANISSLRDGTVPGNGETFPTKAFPDTTYSLFGAFLQDEIQVGNWNITPALRYDKYTLTPHTDGQYKISSAASNGNSFSPKLGVVYQAQPGLNLFAQYGHGFRAPTPEMVNNGFSNPAHGYVTISNPNLKPEASNNFELGLRGQTGTLRYSVSAFIGRYSDFIRQTIVSGAGTPTNPTVYQYVNMDKAQIHGMEARAKWEVNPKLNVLAGLAITRGSLEQNGISNPLDTVDPAKLNLGINYQFSDAWSSNATLTHVAAKSASQSEFGNRDFLPGSYQVFDLSTQYRFNKNLSVNAGIFNLFNHKYYQWSDVRGIAANSVFKDAYSAPGRNVSLNITYQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0X3</accession>
    <name>A0A2S9H0X3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ABC-type hemin transport system ATPase component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_1630</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93629">
        <property type="protein sequence ID" value="PRC93629"/>
        <property type="gene ID" value="S2091_1630"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-1278">Translocase</keyword>
    <feature type="domain" description="ABC transporter" evidence="7">
        <location>
            <begin position="2"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="34"/>
            <end position="41"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC93629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="264" mass="29128" checksum="42D2D9720B310C91" modified="2018-07-18" version="1">MLIADNIKVRIGTNTLLNKVSITIKPGELVAVLGPNGAGKSTLLKALSGERKPEHGSITLNQRPLQQWSSRELAYMRAVLPQESHLSFAFSVQDVVLFGRLPHCQGRMGGISRHDVSIAKLMMEKMGVSHMAQRDFTQLSGGEKSRVQLARVFAQIWEPWQDLPRYLMLDEPTAALDLPHQHYLLQAAKELCRDQAVGIVAILHDVNLAAQYADRIVYLKQGHALASGNVRSMLTADYIKSCFGIPNIVIDHPLTGVPVMLPAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H155</accession>
    <name>A0A2S9H155_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Toxin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_1681</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the RelE toxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93680">
        <property type="protein sequence ID" value="PRC93680"/>
        <property type="gene ID" value="S2091_1681"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2310.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028344">
        <property type="entry name" value="ParE1/4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007712">
        <property type="entry name" value="RelE/ParE_toxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035093">
        <property type="entry name" value="RelE/ParE_toxin_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05016">
        <property type="entry name" value="ParE_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029218">
        <property type="entry name" value="ParE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-1277">Toxin-antitoxin system</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="71"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR029218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC93680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="96" mass="11429" checksum="E49915166EB91723" modified="2018-07-18" version="1">MAEYRLSPAAEHDLEVIWTRTRQQWSIEQANRYIDLLTAAFTELAQSPKIAPTCEHIRPGYRRRNVERHIVYFRITSYGIAIIRILHERMDAPRHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1B3</accession>
    <name>A0A2S9H1B3_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Outer-membrane lipoprotein LolB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">S2091_1381</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">S20-91</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="4">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell outer membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the LolB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93772">
        <property type="protein sequence ID" value="PRC93772"/>
        <property type="gene ID" value="S2091_1381"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16326">
        <property type="entry name" value="LolB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029046">
        <property type="entry name" value="LolA/LolB/LppX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004565">
        <property type="entry name" value="OM_lipoprot_LolB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03550">
        <property type="entry name" value="LolB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89392">
        <property type="entry name" value="SSF89392"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00548">
        <property type="entry name" value="lolB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="10 12" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0564">Palmitate</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11" id="KW-0732">Signal</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015419578" description="Outer-membrane lipoprotein LolB" evidence="11">
        <location>
            <begin position="35"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00016202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PRC93772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="206" mass="22700" checksum="1175817F8A730128" modified="2018-07-18" version="1">MRTSILSSLRYTVLCFAICLSACSSLTPSSPTNASQLPTTREYHQQIEMSGRLSAQYEANNKPQAVHINFSWSQTPQQTLITLGSPTGQTLATILINAQGAQLTQADKAPRFASDANQLFIDMLGWPLPIAGLKDWLQGFITADHATPITEATSNNALVVDGWLLRYASWQTENNVERPKRLDLSRQTEPAGLVSLRIVVDEWNGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1V3</accession>
    <name>A0A2S9H1V3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1532</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93923">
        <property type="protein sequence ID" value="PRC93923"/>
        <property type="gene ID" value="S2091_1532"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="52"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="202" mass="22298" checksum="AF6466823604CE6B" modified="2018-07-18" version="1">MTKPTNSKKSIAAVDTEVGALFEQALAASLQHQSEIAVNILNELLHRDPYHARARHLLGAEYAQAGNIDNALLELFTALELNPAMPLARFQLGLLLLTCARVDDAVNVWMPLDQLGNEHVLNRFRVGMLQMVQGNFEHARQLLATAMAENTELPELNKEMAIVIETIFAAANRDSPLVDAAEEDPNAQHILVSSYLQSPVFH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H262</accession>
    <name>A0A2S9H262_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribonuclease P protein component</fullName>
            <shortName evidence="6">RNase P protein</shortName>
            <shortName evidence="6">RNaseP protein</shortName>
            <ecNumber evidence="6">3.1.26.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Protein C5</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rnpA</name>
        <name evidence="7" type="ORF">S2091_1206</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 6">RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor.</text>
            <dbReference type="EC" id="3.1.26.5"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="6">Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the RnpA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.26.5" evidence="6"/>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94033">
        <property type="protein sequence ID" value="PRC94033"/>
        <property type="gene ID" value="S2091_1206"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004526">
        <property type="term" value="F:ribonuclease P activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001682">
        <property type="term" value="P:tRNA 5'-leader removal"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00227">
        <property type="entry name" value="RNase_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000100">
        <property type="entry name" value="RNase_P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020539">
        <property type="entry name" value="RNase_P_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33992">
        <property type="entry name" value="PTHR33992"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00825">
        <property type="entry name" value="Ribonuclease_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00188">
        <property type="entry name" value="rnpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00648">
        <property type="entry name" value="RIBONUCLEASE_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="5 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 6" id="KW-0540">Nuclease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 6" id="KW-0819">tRNA processing</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC94033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="148" mass="16003" checksum="B4E369C082E39BBB" modified="2018-07-18" version="1">MTGNFERTRRIVKTDEFSSVFRLRPVFKTDHLVLYARPNSLSHARLGVVAAKRLAPRAVTRNAVKRAVREGFRQSELLSSLGLDCVVRLSKSVGSKKEPACTAAIQALLHAEVLSLFAIPSKLNRVLEAAAAAALVIAKPPATDASAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H281</accession>
    <name>A0A2S9H281_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative DNA alkylation repair enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1226</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94053">
        <property type="protein sequence ID" value="PRC94053"/>
        <property type="gene ID" value="S2091_1226"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014825">
        <property type="entry name" value="DNA_alkylation"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08713">
        <property type="entry name" value="DNA_alkylation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="SSF48371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="228" mass="26537" checksum="5AACB462D48FD872" modified="2018-07-18" version="1">MKAQAFTREVECRLLPLANSDRAEAMSAYLLGQFKFLGLPAPIRRAAVKDLIKSPFDDAQKLLEAARMLWAGEEREYRYTAIDLLRHQSHLIGLTDLPAIRDLLLCDPWWETVDGLSAVISTVLHTEHTNKAAIKSIMDEWIVHESFWVRRSAMLHQLGWRLDTDKSRLKRYALKLGHEKEFFIRKAIGWALRDYARWDPEFVREFVIKYGDRLSSLTLRESSKHLDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2C6</accession>
    <name>A0A2S9H2C6_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">50S ribosomal protein L29</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpmC</name>
        <name evidence="6" type="ORF">S2091_1307</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the universal ribosomal protein uL29 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94134">
        <property type="protein sequence ID" value="PRC94134"/>
        <property type="gene ID" value="S2091_1307"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.310">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00374">
        <property type="entry name" value="Ribosomal_L29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001854">
        <property type="entry name" value="Ribosomal_L29/L35"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036049">
        <property type="entry name" value="Ribosomal_L29/L35_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018254">
        <property type="entry name" value="Ribosomal_L29_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00831">
        <property type="entry name" value="Ribosomal_L29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46561">
        <property type="entry name" value="SSF46561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00012">
        <property type="entry name" value="L29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00579">
        <property type="entry name" value="RIBOSOMAL_L29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC94134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="63" mass="7333" checksum="944B7A7D50522100" modified="2018-07-18" version="1">MKVSELRGKDEVTLTKELNELLKAQFSLRMQLATQQLSNTSQLKKVRRDIARVKTVMNQKDDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2H7</accession>
    <name>A0A2S9H2H7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1357</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94184">
        <property type="protein sequence ID" value="PRC94184"/>
        <property type="gene ID" value="S2091_1357"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015779069" evidence="1">
        <location>
            <begin position="26"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="86" mass="9472" checksum="AFA50552DD75E8E8" modified="2018-07-18" version="1">MRDIHEIKSLISLILVALFSTHALADEPPKHNCKQPPVPGKFASDAALRAIERKTDIYKDCIINFADAQQEISKKTAEVAKANQAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2M4</accession>
    <name>A0A2S9H2M4_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">50S ribosomal protein L17</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rplQ</name>
        <name evidence="6" type="ORF">S2091_1289</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="3">Part of the 50S ribosomal subunit. Contacts protein L32.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the bacterial ribosomal protein bL17 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94116">
        <property type="protein sequence ID" value="PRC94116"/>
        <property type="gene ID" value="S2091_1289"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1030.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01368">
        <property type="entry name" value="Ribosomal_L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000456">
        <property type="entry name" value="Ribosomal_L17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036373">
        <property type="entry name" value="Ribosomal_L17_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14413">
        <property type="entry name" value="PTHR14413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01196">
        <property type="entry name" value="Ribosomal_L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64263">
        <property type="entry name" value="SSF64263"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00059">
        <property type="entry name" value="L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01167">
        <property type="entry name" value="RIBOSOMAL_L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1 3 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC94116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="131" mass="15159" checksum="CE620655E777FF95" modified="2018-07-18" version="1">MRHRHGLRKLNRTSSHRLAMLRNMTVSLLRHEAIKTTLPKAKELRRVIEPLLTMGKTDTLANKRLAFSRLRDREMVLKLFAELGPRYANRNGGYLRILKMGFRVGDNAPMAYVELMDRPEITDSEDVVTAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2N8</accession>
    <name>A0A2S9H2N8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0862</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the phD/YefM antitoxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94241">
        <property type="protein sequence ID" value="PRC94241"/>
        <property type="gene ID" value="S2091_0862"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036165">
        <property type="entry name" value="YefM-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143120">
        <property type="entry name" value="SSF143120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009981"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="85" mass="9260" checksum="DB007D0E14CD2FF0" modified="2018-07-18" version="1">MPHITANDLKTKGIAAIEAILQDHTEAIVSVRGHARFVVMELDHYNHLRECELEAALAESRADVTAGRFVDGSADAHVARLLADD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2Q4</accession>
    <name>A0A2S9H2Q4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Patatin-like phospholipase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_0858</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94237">
        <property type="protein sequence ID" value="PRC94237"/>
        <property type="gene ID" value="S2091_0858"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019867">
        <property type="term" value="C:outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000184">
        <property type="entry name" value="Bac_surfAg_D15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002641">
        <property type="entry name" value="PNPLA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01103">
        <property type="entry name" value="Omp85"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01734">
        <property type="entry name" value="Patatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="SSF52151"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51635">
        <property type="entry name" value="PNPLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="1 2" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015442935" evidence="3">
        <location>
            <begin position="22"/>
            <end position="762"/>
        </location>
    </feature>
    <feature type="domain" description="PNPLA" evidence="4">
        <location>
            <begin position="38"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXGXXG" evidence="2">
        <location>
            <begin position="42"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXSXG" evidence="2">
        <location>
            <begin position="69"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="DGA/G" evidence="2">
        <location>
            <begin position="217"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="2">
        <location>
            <position position="71"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC94237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="762" mass="82870" checksum="5D73AFC74838B769" modified="2018-07-18" version="1">MRYFIALFIVLLSLAYFPVVAQENTPDIPTKSNPKICVVLSGGGARGFAHIGVLKYLEEQHIPVHCIAGTSMGAVIGGLYASGMSANEIEQRLNEIKLGDVALDIVDRRKISQTLREDDINYPISGTFGLSKNGVTLPLGAVQANQFLELLHNWTAHLPPDIAFDQLPIPFRAVATDLETGEMVVFDKGPIHNAIRASMAAPGVFAPIEINGHLLSDGGLVRNLPVDIARSMGADVIIAVNIGTPLLPRQDLQSFFNISKQMVNILTEQNVNEQKKILLPTDVLIDPNLGDINFMDFPRAIEAVDIGYKAAQSMHDKLALLSVEPASYSAQLKARTIPDLHPITIAFVDVHSKGKIPPDDIRRQLNIPIGSIYNAEDINKRITPLINSRNFDSVVHSLVQRDGEYGVQIDATERSWGPNFVRVGLAMSTGFDGVSGFELQVGHRLPAITDSGLEWRNDLQFGYAYGIRSELRQPLIVREGMYVAPYINAQMKPLNLYSDNTRVAEYAMQTSQIGLDLGIPIGANASLGEIRTGFFASHTDLRPKLGGLVTEQSDGNTSITSLPWGKTDEFALHTRFTIDQLDTPVFPRDGYRLGGELIAGLNRTSSDSSTLDTHNDLRGFQQATVDSTWADSAEDHSINLSMQAGARYQSGSPIPGVGLSLGGFQRLTAYQPDQFIGNYLVYGNATYLFRAVNFGMAGEAAFVGTSLEVGNAGNFKSDFQLANLRKSLSVFVGANTFMGPVHFGIAIAPAGAFNLFLQLGRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2S0</accession>
    <name>A0A2S9H2S0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cystathionine beta-lyases/cystathionine gamma-synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_0889</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 3">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the trans-sulfuration enzymes family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94268">
        <property type="protein sequence ID" value="PRC94268"/>
        <property type="gene ID" value="S2091_0889"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019346">
        <property type="term" value="P:transsulfuration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00614">
        <property type="entry name" value="CGS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000277">
        <property type="entry name" value="Cys/Met-Metab_PyrdxlP-dep_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11808">
        <property type="entry name" value="PTHR11808"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01053">
        <property type="entry name" value="Cys_Met_Meta_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001434">
        <property type="entry name" value="CGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00868">
        <property type="entry name" value="CYS_MET_METAB_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="2 3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="2">
        <location>
            <position position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR001434-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU362118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC94268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="394" mass="42681" checksum="ED650268350EDC2E" modified="2018-07-18" version="1">MSSTDKTNNTQFATRVIHAGQSPDPSTGAIMPPIYATSTYVQESPGVHKGLDYGRSHNPTRWALERCVADLEGGSQAFAFASGLAAISTVLEVLETGSHIVAGDDMYGGTFRLFERVRRRSAGLRFSYADLTNPENLLAALQPDTKMVWVETPTNPMLKLADLSAIAAICRERGIISVADNTFASPFNQRPLELGIDVVVHSTTKYLNGHSDIIGGIAIVGKESHHAGLQEQLAFLQNSVGAIAGPFDCFLALRGVKTLALRVERHNQNALELAQWLEQHPKVAKVYYPGLKSHPQHALALRQMDGFGGIISVNLKTDLAGSRRFLERCEIFALAESLGGVESLIEHPAIMTHASVPPQQRAALGISDTLIRLSVGIEALEDLRQDLINAFDAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2V4</accession>
    <name>A0A2S9H2V4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0908</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94287">
        <property type="protein sequence ID" value="PRC94287"/>
        <property type="gene ID" value="S2091_0908"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="51"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="296" mass="33388" checksum="DADDCD87D3C0ECC9" modified="2018-07-18" version="1">MYTNNKTSAVSGQPWWAFPTETTTLRTQDFGGYTVAVRGPTLEEYIDGPNVFLVHGMVDSSDTWDALLPALSHCNIWRLDLPWSGRDGVSWPTLQPALKWLQAALALCPIKRGIFVGHSFGATVLLDWLATDPTARQMADGMLLFAPLYCDAQRPVSWPDFDLFARGVQYRFEKNLRIRMGCDVPSDATVCAIATQLSERFLPDAMLELFRIFLSSRHWEFKQLQLPVKLVIGEKENPITRHNINEMINSLPGAECHTLAGCGHYSIHEQPAMLRALLSEFLVRVRMPESSHALRM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2Y3</accession>
    <name>A0A2S9H2Y3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0963</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94342">
        <property type="protein sequence ID" value="PRC94342"/>
        <property type="gene ID" value="S2091_0963"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="68" mass="7787" checksum="4B3FD9FB0A42288A" modified="2018-07-18" version="1">MDASKWSHFVAKKELIEEALVMTHTLSYIKFRLILRDLQPLSCQLLKLTTTFSKLQQIDVIVKGSPLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2Y7</accession>
    <name>A0A2S9H2Y7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Glycosyl transferases group 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0970</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94349">
        <property type="protein sequence ID" value="PRC94349"/>
        <property type="gene ID" value="S2091_0970"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="395" mass="44396" checksum="016CE0CA102A9917" modified="2018-07-18" version="1">MTLSIHIVTGQFPPTAGGLELWTQELAANLAPRLASVTIYVTGDQREIAAPTANYEIVSIGRDRSVWERSIEKASWSEARKENERARLNFLLLRNAISDRVERKKESHHIIVSNFAMTVGQLAMLVADDLALPHVTTIVGTDFSRGFRNLRERISLREVCQSARLIVCKSTEQSNRLSSLTRTPIITIPTSVNVEELLHSPEKKTEVIRLIADSGLSYHKGSDVLINAFLTLLEANLPVTLKIYGKIEEHQKDYWESRLKDVQTRAGQAFSFMNYVSRDEIYTELLHSSIYCSATLGEGSSAARIQALCSGIPIVTTRCGEFAGDVTEVADHIRLARIADSEDYTRQLNSMALDMLAGHVSINHDFVWMWRKRFAPAREWASWVNAFEMATKDSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2Z9</accession>
    <name>A0A2S9H2Z9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">TonB dependent receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0961</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94340">
        <property type="protein sequence ID" value="PRC94340"/>
        <property type="gene ID" value="S2091_0961"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0675">Receptor</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TonB_dep_Rec" evidence="1">
        <location>
            <begin position="25"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="389" mass="42288" checksum="97F8BF2F95064B50" modified="2018-07-18" version="1">MPLTGGSLAYAVGFSVNKEALQDTPDFNQINDNVFGGIRQAAVNASRTSSGVFGELSIPFHKNVEAQVAARYDNISNVGNKTSPKVAIRYQPLPSLMLRASYAESFLAPTLKQMFGGQEAGAQTTEDKKLCSAFPIISDACDPFSYSRVSGSNLNLKPETGKTFNFGVVIEPISAVSIGVDYFRINKKNEIGKPSVFQALKNGHFGVVNGEAQIYMTNQNMASTDVEGFDIDLRYKTGSTPLGKITVRNTTTWYTKTNSQEIAGEEMGKYLGTFANPKYRNVITASLDNDEWNATASVRTVGGMIDFASSLDNIPPGTRFIPAHSELDVMGQYTGLKNLTFTGGVKNLMGKMPPYSDMGTLGQYGSGGFAQLYSPRGRYLYVGLNYKFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H315</accession>
    <name>A0A2S9H315_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0968</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94347">
        <property type="protein sequence ID" value="PRC94347"/>
        <property type="gene ID" value="S2091_0968"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="308" mass="35195" checksum="BC6F309437D957AF" modified="2018-07-18" version="1">MKPDCRIWAVTAYFNPCAYKSRRENYRLFRERLNIPLLAIELRCNDHFDLSDDDADIVVRVAEGSSLWQKERLLNVAVNHLPSDVEYIVFVDCDIIFERSDWADELQRVLEHFPVVQCYSELVDLPKDHNSSEKMPNSISGYSVAWLAQSGELDGPLKSDTARRRSSAGGAWAVRRDLIKKHNLYDVMVLGGADRLFAYACLGKFEEAITLARLGPRRAQHYLDWAKPLHQTVCGNIGVIEGRIYHLWHGTVSDRRYIERHEALENAGFDPDQHIALGTSGAWEWTSAAPASLRRLAQDHFQARNEDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H320</accession>
    <name>A0A2S9H320_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ABC-type antimicrobial peptide transport system ATPase component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_1000</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94379">
        <property type="protein sequence ID" value="PRC94379"/>
        <property type="gene ID" value="S2091_1000"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03255">
        <property type="entry name" value="ABC_MJ0796_LolCDE_FtsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017911">
        <property type="entry name" value="MacB_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-1278">Translocase</keyword>
    <feature type="domain" description="ABC transporter" evidence="7">
        <location>
            <begin position="4"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="40"/>
            <end position="47"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC94379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="222" mass="23767" checksum="B5A3C618E8A0B71D" modified="2018-07-18" version="1">MVALHVTELSKRYKRDAEAFTALDKVSFSIQPGELVALTGPSGSGKSTLLNIIAGYDQADGGSVVVNGFDVTRAKPTQMDALRTRTVGFIFQQFHLVPGLNAVENVELSLLNTGMSKAERRACATEALRRMGLAEHSSRRPAQLSGGQQQRVAVARALAAKPSVVLADEPTAALDRANAESLMDQLAALARESGMAALVSTHDQRCLDRVDRIIRLENGVLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H359</accession>
    <name>A0A2S9H359_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1032</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94411">
        <property type="protein sequence ID" value="PRC94411"/>
        <property type="gene ID" value="S2091_1032"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="44" mass="5022" checksum="AD7D633E59489C07" modified="2018-07-18" version="1">MQMSDISFGTTDWLQNDKVEHKGERATLKSSIRLSERQIKALAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3C9</accession>
    <name>A0A2S9H3C9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">RNA polymerase sigma-70 factor, TIGR02943 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_1088</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94467">
        <property type="protein sequence ID" value="PRC94467"/>
        <property type="gene ID" value="S2091_1088"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014289">
        <property type="entry name" value="RNA_pol_sigma-24-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02943">
        <property type="entry name" value="Sig70_famx1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="2">
        <location>
            <begin position="11"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="3">
        <location>
            <begin position="127"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC94467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="187" mass="21485" checksum="DDAD339A641F4589" modified="2018-07-18" version="1">MTTPTLFQQLEAMRPALLRFALLQLRNPELAEDSVQDALLAVLEKPDQFAGASSLRTYVIGILKFKIIDGLRVAGRTVQIETETDQSEDDVIDHLFQANGHTVDPPRAWGNPEAVLEQQDFFKVMEVCLEKLPAQNARVFMMREWLDLETEEICKELNLSASNLWVILYRARLRLRECLDINWFAHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3N6</accession>
    <name>A0A2S9H3N6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0598</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94595">
        <property type="protein sequence ID" value="PRC94595"/>
        <property type="gene ID" value="S2091_0598"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015473161" evidence="1">
        <location>
            <begin position="29"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="180" mass="19954" checksum="609B9E38E6649D99" modified="2018-07-18" version="1">MKFHRIFKQLCAALVIITSVTVPIFAQAGRGPSTAEEQARVVQLALASDKDPVGTMTSADGRWFEKWADEIPDYQFGPDSGAFWFENGAAKGELKRVIRFQHTVSTAAFQVQHHMFDPQKNPADFEAKTLAGVEGLLRAYESLLAKNPANRSEQLDHAMALRDKGELAAFVKALPPMPRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3P2</accession>
    <name>A0A2S9H3P2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0590</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94587">
        <property type="protein sequence ID" value="PRC94587"/>
        <property type="gene ID" value="S2091_0590"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="48" mass="5376" checksum="7BB62449AC90B26A" modified="2018-07-18" version="1">MRVNALEKMGGPEALQLQVMLCAQTFEFDNLRCSHNLTKSGHVLGNWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3V1</accession>
    <name>A0A2S9H3V1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glutathione-dependent formaldehyde-activating enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_0667</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Gfa family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94664">
        <property type="protein sequence ID" value="PRC94664"/>
        <property type="gene ID" value="S2091_0667"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016846">
        <property type="term" value="F:carbon-sulfur lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006913">
        <property type="entry name" value="CENP-V/GFA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011057">
        <property type="entry name" value="Mss4-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51316">
        <property type="entry name" value="SSF51316"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51891">
        <property type="entry name" value="CENP_V_GFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CENP-V/GFA" evidence="3">
        <location>
            <begin position="6"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC94664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="150" mass="16910" checksum="E5E07F22E3B96BA5" modified="2018-07-18" version="1">MITHNLNGQCYCGNIQLEVGLTSAPLAYEPRACDCDFCRKHGASYISDPQGFLRIHVNDEHNFGKYRQGSEVADFLLCRNCGVLVAVTFQSEGQLYATLNSKVIDGEAHFGMEKTASPKMLAENQKTERWKKLWFSNVSICIDKNKQKNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3V9</accession>
    <name>A0A2S9H3V9_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ABC_trans_aux domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0559</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94556">
        <property type="protein sequence ID" value="PRC94556"/>
        <property type="gene ID" value="S2091_0559"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005586">
        <property type="entry name" value="ABC_trans_aux"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03886">
        <property type="entry name" value="ABC_trans_aux"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015766710" description="ABC_trans_aux domain-containing protein" evidence="1">
        <location>
            <begin position="31"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="domain" description="ABC_trans_aux" evidence="2">
        <location>
            <begin position="44"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="206" mass="22531" checksum="5877B9745B566851" modified="2018-07-18" version="1">MKTNSYLLSSSRLLKYAAIPLLPLFLQACASAPTTLSYYDFGAPTASTPLTCTLPAIHLPDITSPNSLDSNAMLYRLTYINDQQALTYANNRWSMSPAQLLTERIKAHLTDSGATLIDNGVNNANGMQLRLELVDFSQYFSDTTHSYSQLKLRASLIRKGTLLAQTTLQQQANANAPDAQAGAQAMRIATGALMNDVNIWLCKQPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3Z8</accession>
    <name>A0A2S9H3Z8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0701</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94698">
        <property type="protein sequence ID" value="PRC94698"/>
        <property type="gene ID" value="S2091_0701"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="10"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="303" mass="33467" checksum="1A94FF42B7572861" modified="2018-07-18" version="1">MQKRLTTEEPSWELYRSFLAVARLGSLSAAARSLDTTQPTIGRHIEALEMQLKTALFSRSPVGLVPNAIALELIPHAETMAAAAEALIRRASGEAGKEHGTVRITASTIVGGEVLPGLLAPFHRQYPEITLELVLTNEPEDMLRRDADIAIRMFRPTQGALIARRVGPVAVGLYVHRSYAEVIGLPKRIDQLDGHTLIGYDRNPFAIHSAQQLGIQLSRDQFNFRCDNELAQLSALRAGIGIGACQKPIAARDQNLLPVLPKVVALELDMWLVMHEDMRNCRRIMLLFNYLKDGLATYCKGTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H422</accession>
    <name>A0A2S9H422_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Gloeo Verruco repeat</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0732</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94729">
        <property type="protein sequence ID" value="PRC94729"/>
        <property type="gene ID" value="S2091_0732"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022519">
        <property type="entry name" value="Gloeo/Verruco_rpt"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03803">
        <property type="entry name" value="Gloeo_Verruco"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="441" mass="45284" checksum="2B953DC122B4693F" modified="2018-07-18" version="1">MHANVAELATGTQLTLRNSAEEAINATNECKYSVTQPVATTPGIDRHVCTHHTPVVTLLYSFGTNGGQLDGSGPQAGLVQANDGNFYGTTFSGGTNQNATWGAAGTVFKITTDGKESIIYNFGASATDGALPMGTLVVGHDGNLYGTTMVGGAPCFSDGGCGTVFKMTPGGRETQLFSIVSWSQGFEFPAGLTIGTKGNFYGVTTAGGPQWVNYGCCGMVFNINTSGVQIPLYGFGDNGIVNDGNAPEASVIVASDGNLYGTTEFGGAYGPTYGIGVQGSGTVFRITPDGTESIIYSFGAGGITDGARPLAQLVQGPDGNLYGTTIAGGTYNQGTVFRISLNGTMTILYSFGTTTDDGTQPSAGLTFGPDRNMYGTTSSGGVNGGGTVYRMTLSGQEEVVDSFDGNTLPVANLVRGRDGSMYGTTSRGGSYGQGMVYKLTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H488</accession>
    <name>A0A2S9H488_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Deoxyguanosinetriphosphate triphosphohydrolase-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0790</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the dGTPase family. Type 2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94787">
        <property type="protein sequence ID" value="PRC94787"/>
        <property type="gene ID" value="S2091_0790"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016793">
        <property type="term" value="F:triphosphoric monoester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01212">
        <property type="entry name" value="dGTPase_type2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006261">
        <property type="entry name" value="dNTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023023">
        <property type="entry name" value="dNTPase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026875">
        <property type="entry name" value="PHydrolase_assoc_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01966">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13286">
        <property type="entry name" value="HD_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01353">
        <property type="entry name" value="dGTP_triPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51831">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HD" evidence="2">
        <location>
            <begin position="68"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="378" mass="43363" checksum="CD14F339F8B70748" modified="2018-07-18" version="1">MDKIQSPLAHYAAHDTLPARRIFDELPATARSEFGRDRDRIIHSSAFRRLEYKTQVFVNHEGDLFRTRLTHSIEVAQIARAIARNLRLNEDLVEAISLAHDLGHTPFGHAGQDALNSCMQPYGGFEHNLQSLRVVDVLEERYGSFDGLNLTFETREGILKHCSLKNAQQLGEIGQRFIERKQPSLEAQLTNLADEIAYNNHDVDDGLRSGLMQESQLMEVALYAHNRALVEKAFPGLTGRRAIAETIRRMINALILDLITTSEQRILAQQPRNINDVRNAPPLIAFSDQMQAQATELKQFLHVQLYRHYQVQRMTSKARRCVSELFNLFMNEPVLLPPDYLVHDNEAKQARKIADYIAGMTDRYAMREHRRLFVIDDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4A5</accession>
    <name>A0A2S9H4A5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Oxidoreductase molybdopterin binding domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_0010</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mo-molybdopterin</name>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94815">
        <property type="protein sequence ID" value="PRC94815"/>
        <property type="gene ID" value="S2091_0010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030151">
        <property type="term" value="F:molybdenum ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005066">
        <property type="entry name" value="MoCF_OxRdtse_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008335">
        <property type="entry name" value="Mopterin_OxRdtase_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000572">
        <property type="entry name" value="OxRdtase_Mopterin-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036374">
        <property type="entry name" value="OxRdtase_Mopterin-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03404">
        <property type="entry name" value="Mo-co_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00174">
        <property type="entry name" value="Oxidored_molyb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00407">
        <property type="entry name" value="EUMOPTERIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56524">
        <property type="entry name" value="SSF56524"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="SSF81296"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0500">Molybdenum</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015497658" evidence="4">
        <location>
            <begin position="42"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="domain" description="Oxidored_molyb" evidence="5">
        <location>
            <begin position="103"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="domain" description="Mo-co_dimer" evidence="6">
        <location>
            <begin position="300"/>
            <end position="408"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC94815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="417" mass="45368" checksum="300B6B41E091F996" modified="2018-07-18" version="1">MNKNLVNNNAIDASARRQFLRRASASGIGAMLAGSAWPALASNPTVQLPFENGTRELVAFPQKRPLILLTSRPPQLETPFEVFNDSVITPNDAFFVRYHWSGIPTSIDPTTYRLKVGGKVAAPLELSLTELKQLADPVSLTAVNQCSGNSRGFFEPRANGGQLANGAMGNAVWTGIPLKKLLEKAGVQAGAVQVSFNGLDAPLFPDSPDFLKALNIDHALDGEVMLAWAMNGEDLPMLNGYPLRLIVPGYYGTYWVKHLSEIEVLDKPFEGFWMNPAYRIPDNPCACVTPGTAPTKTVPISRLNVRSFITSLTNGAQVSVGQPIVVRGMAFDSGYGITEVAFSSDGGASWQTTKLGTDLGRYSFREWTVQFTPKQIGQHELKVRAVNRIGQSQPMTALWNPAGYMRNVVETTRVNAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4E2</accession>
    <name>A0A2S9H4E2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0044</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94849">
        <property type="protein sequence ID" value="PRC94849"/>
        <property type="gene ID" value="S2091_0044"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008641">
        <property type="term" value="F:ubiquitin-like modifier activating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045886">
        <property type="entry name" value="ThiF/MoeB/HesA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000594">
        <property type="entry name" value="ThiF_NAD_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035985">
        <property type="entry name" value="Ubiquitin-activating_enz"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43267">
        <property type="entry name" value="PTHR43267"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00899">
        <property type="entry name" value="ThiF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69572">
        <property type="entry name" value="SSF69572"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ThiF" evidence="1">
        <location>
            <begin position="15"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="263" mass="28096" checksum="80F96DD0BCC6AA00" modified="2018-07-18" version="1">MEEMDFERRFGGIARLYGADGLAKFKAAHVCVVGVGGVGSWVVEALARSAIGKITLIDLDNVAESNINRQIQALTSTLGQAKVTALAERIAQINPSCQVIQVEDFITPENLPEMIKAPQFDYVVDAIDSVKAKTALLAFCRAEAIPVVTIGGAGGQIDPSRIEIRDLCRTEQEPLLSLVRKRLRQNYGFPRGTKNKFGIDAVFSMEPLKFPDASCAVDDVVDAAATEDGITGLNCAGFGSAMVVTASFGMQATAFVLRKLAGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4I4</accession>
    <name>A0A2S9H4I4_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">30S ribosomal protein S20</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">rpsT</name>
        <name evidence="10" type="ORF">S2091_0087</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 8">Binds directly to 16S ribosomal RNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the bacterial ribosomal protein bS20 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94892">
        <property type="protein sequence ID" value="PRC94892"/>
        <property type="gene ID" value="S2091_0087"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00500">
        <property type="entry name" value="Ribosomal_S20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002583">
        <property type="entry name" value="Ribosomal_S20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036510">
        <property type="entry name" value="Ribosomal_S20_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33398">
        <property type="entry name" value="PTHR33398"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01649">
        <property type="entry name" value="Ribosomal_S20p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46992">
        <property type="entry name" value="SSF46992"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00029">
        <property type="entry name" value="S20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="6 8 10" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5 8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 8" id="KW-0699">rRNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015666"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC94892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="87" mass="9332" checksum="1E1F56F28033BD6A" modified="2018-07-18" version="1">MANTAQARKRARQAVKQNAHNSSQRSTLRTAIKAVRKAILAGDKAVATSIFQASVSTIDSIADKKIIHKNKAARHKSRLAAALKALS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4S4</accession>
    <name>A0A2S9H4S4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Tetratricopeptide repeat</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_0174</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94979">
        <property type="protein sequence ID" value="PRC94979"/>
        <property type="gene ID" value="S2091_0174"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015677173" evidence="3">
        <location>
            <begin position="25"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="132"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="220"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="223"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC94979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="271" mass="28305" checksum="CE14638402CA3F53" modified="2018-07-18" version="1">MNTKSVFQATFLSLAILCSAPSFAAEEPSMQQVYDTAKAGRVDEAQTMMQKVLQDHPSSAKAHFVEAELLAKQGRIASAQAELSNADRLAPGLPFAKPEAVENLRRLIANPQRSSMPRQAVNDYAAPANTGMPWGLILVGLGLIGFIIFAVRFMSNRNPPVVYSQNGATGYGSGVPMQPYGAPGQMMGGGGIGSGIVGGLVTGAALGAGMVAGEELMHHFTDGDNRNNSQPQPTDRNDYVPQNDMGGNDFGIADNSSWDSGGGDSGGGGDW</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4T6</accession>
    <name>A0A2S9H4T6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Electron transfer flavoprotein beta subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_0195</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ETF beta-subunit/FixA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95000">
        <property type="protein sequence ID" value="PRC95000"/>
        <property type="gene ID" value="S2091_0195"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01714">
        <property type="entry name" value="ETF_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000049">
        <property type="entry name" value="ET-Flavoprotein_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014730">
        <property type="entry name" value="ETF_a/b_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012255">
        <property type="entry name" value="ETF_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033948">
        <property type="entry name" value="ETF_beta_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21294">
        <property type="entry name" value="PTHR21294"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01012">
        <property type="entry name" value="ETF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000090">
        <property type="entry name" value="Beta-ETF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00893">
        <property type="entry name" value="ETF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01065">
        <property type="entry name" value="ETF_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0249">Electron transport</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ETF" evidence="3">
        <location>
            <begin position="23"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC95000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="249" mass="26645" checksum="3392BECE8B762D9A" modified="2018-07-18" version="1">MKILVPVKRVVDYNVKVRVKSDQSGMDIANVKMSMNPFDEIAIEEAVRLKEAGVATEIIAISCGVAQCQETLRTAMAIGADCGILVESDAELQPLAVAKLLKAIADKEQPSLIILGKQAIDDDCNQTGQMLAALLGWPQATFASKVVVADGKVSVTREVDGGLETLSLTLPAIITTDLRLNEPRYVTLPNIMKAKKKQLDNVKPADLGVDVAPRVKTLKVVEPAQRSAGIIVPDVATLVAKLKNEAKVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4U2</accession>
    <name>A0A2S9H4U2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein involved in an early stage of isoprenoid biosynthesis</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0091</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94896">
        <property type="protein sequence ID" value="PRC94896"/>
        <property type="gene ID" value="S2091_0091"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026041">
        <property type="entry name" value="ElbB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10224:SF12">
        <property type="entry name" value="PTHR10224:SF12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006320">
        <property type="entry name" value="Elb2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="222" mass="23411" checksum="A56CDB3847E93226" modified="2018-07-18" version="1">MKVAIVLSGCGVFDGAEIHESVLTMLALSCAGVPYQCMAPNINQAHVINHLTGQVTEGENRNVLVESARIARGEIIDIKNADSHDYAAVFFPGGFGAAKNLSDFAFKGSACQIQPDVLHFAKAMAAAKKPACYICISPTMIPRIYGQDAKLTIGNDQATAQAIEAMGGEHIDCPVQEFVVDAERKLVSTPAYMLAQNIAEAAAGIEAAVEATLAMIATEART</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H519</accession>
    <name>A0A2S9H519_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">RibE: riboflavin synthase, alpha subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_0252</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95057">
        <property type="protein sequence ID" value="PRC95057"/>
        <property type="gene ID" value="S2091_0252"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00402">
        <property type="entry name" value="Riboflavin_synthase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023366">
        <property type="entry name" value="ATP_synth_asu-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001783">
        <property type="entry name" value="Lumazine-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026017">
        <property type="entry name" value="Lumazine-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21098">
        <property type="entry name" value="PTHR21098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00677">
        <property type="entry name" value="Lum_binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000498">
        <property type="entry name" value="Riboflavin_syn_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="SSF63380"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00187">
        <property type="entry name" value="ribE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51177">
        <property type="entry name" value="LUMAZINE_BIND"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Lumazine-binding" evidence="3">
        <location>
            <begin position="1"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="repeat" description="Lumazine-binding" evidence="2">
        <location>
            <begin position="1"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="repeat" description="Lumazine-binding" evidence="2">
        <location>
            <begin position="100"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="domain" description="Lumazine-binding" evidence="3">
        <location>
            <begin position="100"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC95057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="205" mass="21700" checksum="D5D9507C7779579E" modified="2018-07-18" version="1">MFTGIVAAVGTINTVTPLSTQTDSGLRLSIDAGALAMSDVILGDSIAINGACMTVVSKTEQQFCIDISRESLNLTSGLDQPGPVNLEKALTLADRIGGHLVSGHVDGLGTVTTFKQVNESFELVIAAPKNLAKYLAYKGSIVVNGVSLTVNRVQDLAECCEFSINLIPHTLQVTTLKHLQVGAKVNLEIDLIARYVERMMSVDAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H521</accession>
    <name>A0A2S9H521_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Heavy metal efflux pump, CzcA family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_0274</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95079">
        <property type="protein sequence ID" value="PRC95079"/>
        <property type="gene ID" value="S2091_0274"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2090.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027463">
        <property type="entry name" value="AcrB_DN_DC_subdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001036">
        <property type="entry name" value="Acrflvin-R"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004763">
        <property type="entry name" value="CzcA/CusA/SilA/NccA/HelA/CnrA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32063">
        <property type="entry name" value="PTHR32063"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00873">
        <property type="entry name" value="ACR_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00702">
        <property type="entry name" value="ACRIFLAVINRP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82714">
        <property type="entry name" value="SSF82714"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00914">
        <property type="entry name" value="2A0601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="340"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="363"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="389"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="446"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="478"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="533"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="867"/>
            <end position="886"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="893"/>
            <end position="917"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="923"/>
            <end position="944"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="965"/>
            <end position="984"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="996"/>
            <end position="1019"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC95079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="1039" mass="112847" checksum="47A2F499937B6E94" modified="2018-07-18" version="1">MLNKIIELSLRYKVLVLLAFMLVILLGGKAWRDLPVDAFPDVTPIQVNIYTESPGLAAEDVEKLLTTPVETAMAGLAGVEAIRSVSLFGLSYVSVNFHDNVDIYFARRLVGEKLLEAKAQIPDGYGEPTMGPNSSGLGQVFWYTIESQDQKMSNMDLRTLQDWNVRLKLRTAAGVDDVTSWGGDEKQYQVLINPNQLIKYGISLKTVMETLTANNRQVGGQYLNIGQEQYLVRGLGLVANAKDIGNVVLATREGSPIYVRDVAEVKEGAALRSGAITKDGKEVVMGIALQRMGENAKSVVETVKEKIKLAEQTLPNGVVIKPVYDRTVLVDKAVKTAENALIEGSILVAIILFLFLGEIRSAIVVIVVLPLAMLISFMLMQHFGLSANLMSLAGLAVGIGMMVDGAVVMVENSFRLLSHSVDKATGKAVNKTQLILAAGREVMNPIAFAILIIIVVFLPLFSLTGLEGKMFKPMALSITFAMIGSLLLTMTLVPVLSALILKAKEEKDTFLVRHAKRLYLPILDWSLENKKKVVTGAVIGLFASLALLPLLGKEFMPTLQEGAILFRITSIPSTSLEESIRISEVMETTLNQFPQTEASIAMIGRAEKGETADVNAMELLVNLKPVTTWPKKISVPDLAKEMQAKLEQAVPNAVIAATQPIESRIEELISGVRATLALKLVGEDLNTLDKVSAELKEVLEKVPGVADLSLEANKGKPQLVIQVNREAAARYGINADEILEIVQAGIGGKAVSTVIEGTKRFDIQVWLAAEFRQSAAAISAIPIRTESGALVPLSAVASVELDEGYSFIRREQLQRYAVIQMDVEGRDVDGFVKEAEAKIKQQVKLPEGYVIEWGGAFENQQRAMSKLMLIIPLTIGLIFVLLYTAFNSLSYATLIIANVPFASIGGILGLLLTGQYLSVPSAIGFITVFGVAMLNGIVLITFLNDQLKLGLSVREAVRQGTVMRLRPVLMTASIAIFGLVPMLLSSGVGAETQRPLATVVVGGLFSSTLLTLLLLPLLYEWIENRKKKEQEEDTQPATD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H591</accession>
    <name>A0A2S9H591_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">5'-nucleotidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0333</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95138">
        <property type="protein sequence ID" value="PRC95138"/>
        <property type="gene ID" value="S2091_0333"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008253">
        <property type="term" value="F:5'-nucleotidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009117">
        <property type="term" value="P:nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010394">
        <property type="entry name" value="5-nucleotidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31367">
        <property type="entry name" value="PTHR31367"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06189">
        <property type="entry name" value="5-nucleotidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC95138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="298" mass="32969" checksum="C8F103C7412A6AD1" modified="2018-07-18" version="1">MPVSLENLLVIGVSSRALFDLETEEDIFQQQGLANYRQHQLEHENTILKPGAGFALVRALLKLNALTPDKRLVEVVIMSRNSSETSLRIFNSIKHYDLDITRAALTGGSMLAPYLKAFNISLFLSKHEEDVRAAASSGVAAALLYQKPDKITQELDQIRIAFDGDAVIFSDASERIYQEHGVEAFEQHERENARNPLVAGPFAPVLKALAFIQTHFKAPDGQSSPIRTALVTARASPAHERVIRTLRAWDVLIDETFFMGGVEKSAVLAAFQPHMFFDDQHGHCQLAAPLVQTGRVLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5D4</accession>
    <name>A0A2S9H5D4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CheR methyltransferase, SAM binding domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0372</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95177">
        <property type="protein sequence ID" value="PRC95177"/>
        <property type="gene ID" value="S2091_0372"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022642">
        <property type="entry name" value="CheR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000780">
        <property type="entry name" value="CheR_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01739">
        <property type="entry name" value="CheR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00996">
        <property type="entry name" value="CHERMTFRASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00138">
        <property type="entry name" value="MeTrc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50123">
        <property type="entry name" value="CHER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="CheR-type methyltransferase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC95177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="504" mass="56580" checksum="3B542C6B5A934542" modified="2018-07-18" version="1">MMLLPSAQEISRFRTKIVELMGLNFDESKFDILAKVLHSRMLANGMEHTPYIDSLDTRSSEEIRLLARELTVTETYFLRNIDQFNAFAEVALPERLAVHDGNRNIEVLSAGCASGEEPYSLAITVREHCSYAADRISITAFDLNPAMLQKAAQARYSNWSLRDLSDELKKRWFKVGGDAFNLNDAIRKSVVFESRNLTQDGADFWSPARFDVVFCRNVLMYFSNDQAQAAVDRIARAMAPGGYLFLGHAETLRGISNDFHLRHSHDTFYYQRKEHIVSSHVRLPQLQPRVRWKPAASLSADTSWIEAIQRASDRIQALTPAVEVAMFDNAIYVGDRPMPDLHRVLESLHSERYDRSLDQIGNLPVQHAHDPDVLLLKAVSLIHSGALAEAEVVCEELLKCDEFNAGAHYVLALCREGAGDLDGAVEHDQTATYLDPKFAMPRLHLGLVSRRQGEHDSARKDLGLALLLLQHEDASRVLLFGGGFKREALLALCRAELAALGENK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5K9</accession>
    <name>A0A2S9H5K9_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Aminopeptidase N</fullName>
            <ecNumber evidence="4">3.4.11.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">S2091_0433</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Release of an N-terminal amino acid, Xaa-|-Yaa- from a peptide, amide or arylamide. Xaa is preferably Ala, but may be most amino acids including Pro (slow action). When a terminal hydrophobic residue is followed by a prolyl residue, the two may be released as an intact Xaa-Pro dipeptide.</text>
            <dbReference type="EC" id="3.4.11.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the peptidase M1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.2" evidence="4"/>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95238">
        <property type="protein sequence ID" value="PRC95238"/>
        <property type="gene ID" value="S2091_0433"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.50.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1730">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1840">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045357">
        <property type="entry name" value="Aminopeptidase_N-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042097">
        <property type="entry name" value="Aminopeptidase_N-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038438">
        <property type="entry name" value="PepN_Ig-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001930">
        <property type="entry name" value="Peptidase_M1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014782">
        <property type="entry name" value="Peptidase_M1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012779">
        <property type="entry name" value="Peptidase_M1_pepN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024601">
        <property type="entry name" value="Peptidase_M1_pepN_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037144">
        <property type="entry name" value="Peptidase_M1_pepN_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035414">
        <property type="entry name" value="Peptidase_M1_pepN_Ig-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027268">
        <property type="entry name" value="Peptidase_M4/M1_CTD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46322">
        <property type="entry name" value="PTHR46322"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11940">
        <property type="entry name" value="DUF3458"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17432">
        <property type="entry name" value="DUF3458_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01433">
        <property type="entry name" value="Peptidase_M1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17900">
        <property type="entry name" value="Peptidase_M1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00756">
        <property type="entry name" value="ALADIPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63737">
        <property type="entry name" value="SSF63737"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02414">
        <property type="entry name" value="pepN_proteo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="15" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="6" id="KW-0645">Protease</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase_M1_N" evidence="14">
        <location>
            <begin position="65"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M1" evidence="11">
        <location>
            <begin position="266"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="domain" description="DUF3458" evidence="12">
        <location>
            <begin position="488"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="domain" description="DUF3458_C" evidence="13">
        <location>
            <begin position="597"/>
            <end position="933"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012564"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00015611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF11940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF17432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF17900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="PRC95238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="934" mass="105160" checksum="1DCC3CF1A888CD57" modified="2018-07-18" version="1">MLLIFALIDGILYVNPTTLVEYWLAPKITTIPMRTDTNTDSNLTIYRKDYTAPSFWVDTVEMGFDLDPKSTVVSTRTTLKRNTESTEKDLILFGESLKLVQIRMNGQKLARTAYEIDKHSLRIFNPPNEIILDIETQISPIKNTSLSGLYVSNDNFFTQCEAEGFRKITYFQDRPDVMAKFTVMLRADKKKYPVLLSNGNLIEKGKLSDGRHFAKWEDPFKKPSYLFALVAGKLVCQEEKIKLQSGRKALLQVWVEKGNLDKTQHAMDSLQNSIFWDEQRFGLELDLERFMIVAVSDFNMGAMENKGLNIFNTKYVLANSKVATDADYAGIESVVGHEYFHNWTGNRVTCRDWFQLSLKEGLTVFRDQEFSADMIGTNSGRAVNRIADVRVLRQAQFPEDAGPMSHPVRPESYVEINNFYSVTVYEKGAEVVRMYYTLLGHEGFRKGMDLYFKRHDGQAVTCDDFRAAMADSSGRDLTQFERWYSQSGTPRLKVATKYDAAKQTFEMTFTQSCPATAGQDKKQPFHIPVAVGLLNAAGQDMPLHCQEQANPTDSTTLVLEITKAKQVFHFTNVTEQPTPSILRNFSAPVELEMDYSDDQLAHLLAHDSDAFNRWEAGQRLAMRRLLKLTAAVQVQQPLELDTMFIEALRKTLNDSTLDAAFREQVLTLPSTTNVAEQMDVIDPQAIKAARDFMRSEITRHLKADLLTAYENNLTPGKYSPDASSTGMRALKNLALAYLQEWPKSSTFELADSQCANAKNMTDRIGALAAMVNAEILTGGTHKDATKSANKAVAHALKQFYNDFKQEALVIDKWFMLQGSAGSTDVAKMRKLLKHPAFTLSNPNRARSLIFAFCNANPSQFHAADGSGYALWADLVIELNAINPQVAARLARSLDRWRKYTPALQEFMQAALQKVAASKNLSKDVLEIVTKALAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSB8</accession>
    <name>A0A2S9GSB8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4673</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000043">
        <property type="protein sequence ID" value="PRC90622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90622">
        <property type="protein sequence ID" value="PRC90622"/>
        <property type="gene ID" value="S2091_4673"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="75"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="94" mass="11249" checksum="65DD1513805C8CE6" modified="2018-07-18" version="1">MKILTSKNKQLFLLILIIGALCRVLYIYFTLNWLTALWLSICLIWVVWIIFAFFYNKDMYGAFHWNNGENQVPRAMLAITMLGIYFLLLFNDFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSC2</accession>
    <name>A0A2S9GSC2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">RHS repeat-associated core domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4679</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000044">
        <property type="protein sequence ID" value="PRC90611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90611">
        <property type="protein sequence ID" value="PRC90611"/>
        <property type="gene ID" value="S2091_4679"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029118">
        <property type="entry name" value="Ntox16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001826">
        <property type="entry name" value="RHS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022385">
        <property type="entry name" value="Rhs_assc_core"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15523">
        <property type="entry name" value="Ntox16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00394">
        <property type="entry name" value="RHSPROTEIN"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03696">
        <property type="entry name" value="Rhs_assc_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ntox16" evidence="1">
        <location>
            <begin position="125"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF15523"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="207" mass="22642" checksum="1CBEA16D4A1DE9E0" modified="2018-07-18" version="1">MYGESASGGSLDAETNLHYNKFRDFDPTTGRYIESDLIGLAGGLSTYSYTGSNPLTRSDSDGLDWNCSVSGFFVICTHTTPLDPVEPLPPPPQPHLPAWLNQALSPTYDKAGLKVCPTAQTMPPPGDCHPQDQQRMQDTVNNSCKRPRSCKPGMDGVELEIMKENSRECAMARDEINKICFKGGDQGHRDAAIDAWQGVARCEGMMQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSE1</accession>
    <name>A0A2S9GSE1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">RHS repeat-associated core domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4683</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000044">
        <property type="protein sequence ID" value="PRC90615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90615">
        <property type="protein sequence ID" value="PRC90615"/>
        <property type="gene ID" value="S2091_4683"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001826">
        <property type="entry name" value="RHS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022385">
        <property type="entry name" value="Rhs_assc_core"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00394">
        <property type="entry name" value="RHSPROTEIN"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03696">
        <property type="entry name" value="Rhs_assc_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC90615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="183" mass="20648" checksum="E840999115AF1461" modified="2018-07-18" version="1">MYGESASGSSLDAETNLHYNAYRDYDPTTGRYVESDPIGLTGGISTYGYVSGNPLASSDPQGLAPGYRICVMFMCPPELPGLPSWNNTDNLTPEQQAEKDADYLVYKEFQKYGRPPKQNDPNCDELKAQRDFWKQLATMRVDFTDVWYRGIYDFGHLLQVMIAQGKVNKIERQMKAMGCPCDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSF3</accession>
    <name>A0A2S9GSF3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Sporulation related domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_4662</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000042">
        <property type="protein sequence ID" value="PRC90626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90626">
        <property type="protein sequence ID" value="PRC90626"/>
        <property type="gene ID" value="S2091_4662"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042834">
        <property type="term" value="F:peptidoglycan binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1070">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007730">
        <property type="entry name" value="SPOR-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036680">
        <property type="entry name" value="SPOR-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05036">
        <property type="entry name" value="SPOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110997">
        <property type="entry name" value="SSF110997"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51724">
        <property type="entry name" value="SPOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="16"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="domain" description="SPOR" evidence="2">
        <location>
            <begin position="140"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC90626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="220" mass="23285" checksum="4AA595385EEC687C" modified="2018-07-18" version="1">MKSIVKSSMTKQHGGTLLGLIIGLVVGLAIAVVVALMITKTSTPFTNKLGMNKSADAPTVQLTDPNKPLYGNAAKAALANKPAENSVATVATPPEAVRPPDVVKLDTKPDAKIDTKADPKTTVDAKVTKPIDSTVAKNSADEKSAYYLQVGAFRDASDAESARAKLALIGVESHVSEKTAEGDNLYRVRIGPFDQLDTMNRMRSKLSENSIDVAVIKTPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSL2</accession>
    <name>A0A2S9GSL2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glutathione S-transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_4600</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GST superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000038">
        <property type="protein sequence ID" value="PRC90707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90707">
        <property type="protein sequence ID" value="PRC90707"/>
        <property type="gene ID" value="S2091_4600"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00043">
        <property type="entry name" value="GST_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02798">
        <property type="entry name" value="GST_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="SSF47616"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GST N-terminal" evidence="2">
        <location>
            <begin position="18"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="3">
        <location>
            <begin position="108"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC90707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="234" mass="26097" checksum="0D97B3149673D831" modified="2018-07-18" version="1">MTTLSNFPITQKWPAAHPEYIQLYSLPTPNGVKVSIMLEETGLAYEPHLVSFDTNDQMSAAFLSLNPNNKIPAILDPNGPGGKPLALFESGAILLYLAEKSGMFMPKDGADRYETIQWLMFQMGGIGPMFGQLGFFHKFAGKDYEDKRPRDRFTAESIRLLNVLNQRLNGRNWIMGDTYTIADIAIFPWVRNLIGFYGAGDLVGIDNFPHVMRVLDAFVARPAVIRGLAIPART</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSM2</accession>
    <name>A0A2S9GSM2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="8">2A51: chromate transporter, chromate ion transporter (CHR) family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_4589</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000038">
        <property type="protein sequence ID" value="PRC90696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90696">
        <property type="protein sequence ID" value="PRC90696"/>
        <property type="gene ID" value="S2091_4589"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015109">
        <property type="term" value="F:chromate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014047">
        <property type="entry name" value="Chr_Tranpt_l_chain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003370">
        <property type="entry name" value="Chromate_transpt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02417">
        <property type="entry name" value="Chromate_transp"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004810">
        <property type="entry name" value="ChrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00937">
        <property type="entry name" value="2A51"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="82"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="115"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="166"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="198"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="232"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="265"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="294"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="332"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="357"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC90696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="396" mass="42074" checksum="90E4383E12C4923C" modified="2018-07-18" version="1">MSSMPLERCWTIFLLFLRLGLTSFGGPVAHLGYFREEFVTRRRWLSESSYTDLVALCQFLPGPSSSQVGMAIGLLRGGATGALAAWAGFTLPSALMLCLFGMGLSTWGGAVPVGVLHGLKVVAVAVVAQAVWGMARQLCTGATRIAITLAAAGLVLFWPMPLGQVSVIVAAAVLGIVLFKPAQAVLHEPLPITISRRLALLLLGIFFALLIGLPICLEMWPNHLLAMVNAFYRAGALVFGGGHVVLPLLQSAVVSNGWVSNDTFLSGYGMTQAVPGPLFTFSAFLGASMNQSPNGWLCAALCLIAIFTPSFLLIFGVLPFWEQLRRSVHTQAALAGVNAAVVGLLLAALYHPVWTGAIMKLADLALLLAAFFALMFWRLPPWLVVLGCGVGGWLLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSP8</accession>
    <name>A0A2S9GSP8_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Efflux pump membrane transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_4544</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 4">Cell inner membrane</location>
            <topology evidence="2 4">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000037">
        <property type="protein sequence ID" value="PRC90718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90718">
        <property type="protein sequence ID" value="PRC90718"/>
        <property type="gene ID" value="S2091_4544"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015562">
        <property type="term" value="F:efflux transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042908">
        <property type="term" value="P:xenobiotic transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2090.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027463">
        <property type="entry name" value="AcrB_DN_DC_subdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001036">
        <property type="entry name" value="Acrflvin-R"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004764">
        <property type="entry name" value="HAE1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32063">
        <property type="entry name" value="PTHR32063"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00873">
        <property type="entry name" value="ACR_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00702">
        <property type="entry name" value="ACRIFLAVINRP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82714">
        <property type="entry name" value="SSF82714"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00915">
        <property type="entry name" value="2A0602"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="341"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="368"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="396"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="439"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="471"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="549"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="879"/>
            <end position="897"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="904"/>
            <end position="923"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="935"/>
            <end position="956"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="976"/>
            <end position="997"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="1009"/>
            <end position="1035"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU364070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC90718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="1060" mass="114823" checksum="ACE2A588A4F14353" modified="2018-07-18" version="1">MNFSRFFVDKPIFAAVLSIIIFVAGLIAIFQLPISEYPNVVPPSVVVRAQYPGANPKIIAETVAAPLEEQINGVENMLYMTSQNTSDGALALTVTFKVGTNVEQAETEVQNRVQRALPRLPDEVRQIGVTTVKSSPNLTMVVHLISPNGRYDDLYLRNYAVLNIKDQLARISGMGEINLFGSGDYAMRIWLDPQKVAARALTANDVVNAIREQNVQVAAGVIGSSPSKDAEFQLTVNTQGRLKTVEEFGGIIVRTGSDGSTTLLKDVARVELGSNSYDLRSLLNNKSAVAIGIFEAPNANDLQLSADVRAKMDELKKDFPEGVDYKVVYDPTQFVRESIKAVIHTLLEAIALVVLVVILFLQTWRASIIPLLAVPVSIVGTFAVMLGFGFSINTLSLFGLVLAIGIVVDDAIVVVENVERNIANGLTPRDATIQAMKEVSGPIIAIALVLCAVFVPIAFLSGLSGQFYRQFALTIAISTVISAFSSLTLAPALAAALLKPHDAPKDGLTRLMDTLFGRFFGWFNRFFGRASNRYESGVKGILGRKSAAVGVYVLLAVAAGFMFKLVPAGFVPAQDKQYLVGFAQLPDAASLERTTSVIRRMSDVAMQIPGVESSVAFPGLSINGFTNAPNAGIVFTTLKPFDERTKPEESGAAIAAEINKRMGSIQDAFIMVFPPPPVNGLGTIGGFKMMIEDRGNLGYDELYKATQAMQAKAWQTPELAGVFSSFQINVPQLFADVDRTKAKQLGVPLSTIYQTLQINLGSLYVNDFNQFGRTYQVRVQADAPYRSHAEDIAQLKVRNDKGEMIPLSSLMRVKDSYGPDRVQHYNGYVTADLNGGPAPGVSSGQAQVALEKIAHEVLPKGITYEWTELTYQDILSGNTMIYVFPLCVLLVFLVLAAQYESWTLPLAVILIVPMSILCALIGVKLTHGDNNVFTQIALFVLVGLASKNAILIVEFARELEGHGRTVVEAALEACRLRLRPILMTSIAFIMGVVPLVFSHGAGSEMRHAMGVAVFAGMLGVTFFGLFLTPVFYVLLRTLALRLSSKVEVAAVATTKLEGIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSV2</accession>
    <name>A0A2S9GSV2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4460</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000035">
        <property type="protein sequence ID" value="PRC90797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90797">
        <property type="protein sequence ID" value="PRC90797"/>
        <property type="gene ID" value="S2091_4460"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC90797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="166" mass="19446" checksum="C8321B421CBA7C3F" modified="2018-07-18" version="1">MPTKIEHRRHGRRRFCVTLDNRYEFYSWPEDINVKCPNCGSPILFNAVVPDQYVKDEKSGGYLLVPQSVATKIRGRGACTKCSRQFDRISWPEDAHFKFESGGGIVWAWNKEFLQVLRARVIGDRVTERQLCMKNGLFHYFLTRLPKYIVVKRHRAGILRKLDELT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSX7</accession>
    <name>A0A2S9GSX7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4480</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000035">
        <property type="protein sequence ID" value="PRC90817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90817">
        <property type="protein sequence ID" value="PRC90817"/>
        <property type="gene ID" value="S2091_4480"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015431188" evidence="1">
        <location>
            <begin position="27"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="92" mass="9519" checksum="F8DB329D17388F78" modified="2018-07-18" version="1">MTIFRLVRIAASASLLTLSIAGCVVAGGYGGNVGVGVDYYEPVGGVYGAWGPGYQVGPYRDRGHFWGGGAGHHAYHSAAPGRSVPSIPFHSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GT24</accession>
    <name>A0A2S9GT24_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4450</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000034">
        <property type="protein sequence ID" value="PRC90869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90869">
        <property type="protein sequence ID" value="PRC90869"/>
        <property type="gene ID" value="S2091_4450"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032637">
        <property type="entry name" value="Phage_holin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16931">
        <property type="entry name" value="Phage_holin_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="81"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="119" mass="12238" checksum="4E7B067CA0A78EF3" modified="2018-07-18" version="1">MAEPHTSSFIIAATAAGIGLSTLFPGIDGNALIGAFAGSSLVAISSKNLSLLKRLAYMLISLVAGYLAAPEVVAQTPLRESGVAAFLASAAAIALTFHLLDLIKKIQLPSSFEKGKPRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTC0</accession>
    <name>A0A2S9GTC0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transglycosylase SLT domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_4347</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the transglycosylase Slt family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000032">
        <property type="protein sequence ID" value="PRC90946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90946">
        <property type="protein sequence ID" value="PRC90946"/>
        <property type="gene ID" value="S2091_4347"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008933">
        <property type="term" value="F:lytic transglycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000270">
        <property type="term" value="P:peptidoglycan metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023346">
        <property type="entry name" value="Lysozyme-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000189">
        <property type="entry name" value="Transglyc_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008258">
        <property type="entry name" value="Transglycosylase_SLT_dom_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01464">
        <property type="entry name" value="SLT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53955">
        <property type="entry name" value="SSF53955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00922">
        <property type="entry name" value="TRANSGLYCOSYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015642161" evidence="2">
        <location>
            <begin position="25"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="domain" description="SLT" evidence="3">
        <location>
            <begin position="166"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC90946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="296" mass="32683" checksum="2DEBC31A7340212D" modified="2018-07-18" version="1">MASLKYVCLLVYCSTFAIGSSAFAGHVELLLSTDDNIPTEAMVLTKLARQYENAEGIPRDYAFALELYCQAAKLGYADAQYALGWMYANGRGVARDDDVAALLFHTAAQQGHVQAKTMTHYVRSGTIKLPACKSEEISKVVEQQAVLLEKQFPRGQVFDLVEKLSPLYRIDPNLVLAIISVESGFNAHAVSPKNAQGLMQLLPETAQRFGVKDSFNIEQNLKGGIAYLQWLLAYFKGNVVLVAAAYNAGEKAVEKYRGVPPYPETVDYVKRITGLYPKPSHPFQRHIVEASAVVMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTD9</accession>
    <name>A0A2S9GTD9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Phage tail sheath protein FI</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_4276</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the myoviridae tail sheath protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000031">
        <property type="protein sequence ID" value="PRC90980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90980">
        <property type="protein sequence ID" value="PRC90980"/>
        <property type="gene ID" value="S2091_4276"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035089">
        <property type="entry name" value="Phage_sheath_subtilisin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020287">
        <property type="entry name" value="Tail_sheath_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04984">
        <property type="entry name" value="Phage_sheath_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17482">
        <property type="entry name" value="Phage_sheath_1C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phage_sheath_1" evidence="2">
        <location>
            <begin position="108"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="domain" description="Phage_sheath_1C" evidence="3">
        <location>
            <begin position="280"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC90980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="390" mass="42767" checksum="4132FF8C092BEE1D" modified="2018-07-18" version="1">MAADYHHGVRVIEINEGTRPIRTISTAVIGLVATASDADATVFPLNTPVLLTNVIAAAGKAGTKGTLRRTLDAIGMQTKPFTIVVRVAEGADEDETTSNVIGGSDEDGKYTGIKALLAAQSKLGIKPRILGAPGLDNKAVTNALVAVAQQLRGFVYASAYECATKEEAVLYRKDFGQRELMLIWPDFVNWNTATNSETTIPAVAYALGLRAKIDEEIGWHKTLSNMPINGPTGLSRDVFWDLQDPATDAGYLNSKEVTTLINNGGFRFWGSRTAEVPEFFFFENYTRTAQVLADTIAEAHFTYVDKPLHPSLVKDLIESINAKFRDLKAQGYIIDGSAWYDEQFNSKDTLKSGKLAIDYDYTPVPPLENLVFQQRITDRYLADFASRVNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTF7</accession>
    <name>A0A2S9GTF7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Serine/threonine protein phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000031">
        <property type="protein sequence ID" value="PRC91004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91004">
        <property type="protein sequence ID" value="PRC91004"/>
        <property type="gene ID" value="S2091_4300"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006470">
        <property type="term" value="P:protein dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00143">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015655">
        <property type="entry name" value="PP2C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832">
        <property type="entry name" value="PTHR13832"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00331">
        <property type="entry name" value="PP2C_SIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="SSF81606"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="1">
        <location>
            <begin position="6"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="265" mass="29340" checksum="59BADE1730B72055" modified="2018-07-18" version="1">MPNSDSIDYASQTDTGLKRVHNEDAIAVCPESAMTILADGMGGYNAGEVASEIAITVIKDYVNEKLHRFLSHLIPYQPDDLQLIVEQAIELANNTILQAALTEPQYFGMGTTLVMSVCYRDILVVAHVGDSRAYRYRQGQLTQITHDHSVVQEQIDAGMISVETAQYSDIKNLVTRAVGVSYPVETEVNLHQVEIGDVYLLCSDGLSDMLSAQKIQETLQQDNVNIQDMCAELIRLANEEGGRDNISVILFKINSIKNFGLKQLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTM2</accession>
    <name>A0A2S9GTM2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4257</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000030">
        <property type="protein sequence ID" value="PRC91069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91069">
        <property type="protein sequence ID" value="PRC91069"/>
        <property type="gene ID" value="S2091_4257"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.620.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012348">
        <property type="entry name" value="RNR-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="SSF47240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="277" mass="32798" checksum="163276503D987EF1" modified="2018-07-18" version="1">MMNLPNSYQRRSWHLDDIDFNAIDIASVRDDNFLFLTLASASFVEILSEMYAANLIEHFQGDSELTNWLSEYWQRDEVQHGQALRTYVQTVWPDFEWDNAYNAFFMHYSTLCTVEQLEPSKALELLARCVIETGTSSFYRALQQYVREPVLRHLIGHIRADEISHYVYFRKYFTAYNAIERHGVGASIATIWRRLSEIRGEDVYIAFKHVHGDRYSNQPYLEADWRRYNQTVKRLARNYYPYLMTVKMLMKPIPMFESIKKMLQWPLVGLAMLISLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTN6</accession>
    <name>A0A2S9GTN6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_4259</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000030">
        <property type="protein sequence ID" value="PRC91071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91071">
        <property type="protein sequence ID" value="PRC91071"/>
        <property type="gene ID" value="S2091_4259"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004638">
        <property type="entry name" value="EmrB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00711">
        <property type="entry name" value="efflux_EmrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="60"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="87"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="147"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="174"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="208"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="241"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="279"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="312"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="344"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="376"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="490"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="22"/>
            <end position="519"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC91071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="526" mass="56579" checksum="63D996EB71CFBE0D" modified="2018-07-18" version="1">MSTAASATAHANWKPAGNPWLIAVAVTLAAFMEVLDTTIVNVALPHIAGTMSVSYDQATWALTAYLVANGIVLPMSAFLARTIGRKRYFLICIIAFTACSFACGISTNLYELILFRVLQGFFGGGLQPVQQSIILDTFPASQRGRAFAVTAVAIVVAPVFGPTLGGWITDNLSWRWVFLINVPVGVLTAFAVMRLVEDPPWEKIPKKINFDYIGIGLIALGLGSLQVMLDRGEDADWFSSTFIRIFATLALIGLSTAVAWLLYTKKPVVDLRTLKDKNFTLGCLTIAAFASILYASAILIPQLTQLHLGYTALLSGLVLSPGALAIIILIPIINHFMPYVQMRYILSVGFFLLGCAMLYSHGLVPDIDFNTLVMMRITQSVAIGFLFVPASTLTYLTLPKYLQGDGAALFTMFRNIAGSIGISLSTAAITARTQVHQAILAAHTGPLEANYAVSIAHITSALKGSMSAIGDLTQTAAGVMYQNLLQQASILAYMDVFAACAILSWCFIPFTFFFSPAKGKSGEGAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTP6</accession>
    <name>A0A2S9GTP6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Superfamily II DNA and RNA helicase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">S2091_4177</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the DEAD box helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000029">
        <property type="protein sequence ID" value="PRC91081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91081">
        <property type="protein sequence ID" value="PRC91081"/>
        <property type="gene ID" value="S2091_4177"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 6 11" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Q_MOTIF" evidence="10">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="8">
        <location>
            <begin position="32"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="9">
        <location>
            <begin position="261"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="70"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="404"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="5">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="82"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="423"/>
            <end position="448"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC91081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="491" mass="53214" checksum="EE93B2360F789B55" modified="2018-07-18" version="1">MTFEQIGLHASLLKALTEAGYTKPTPVQQQAVPAAIAGRDLLVSSQTGSGKTAAFMLPALHKFASNEQINDTAAGEKTPNQERQSARSRGDRPRFQAAKPKMLVLTPTRELALQVTTATDKYGSFLRKIRAVSILGGMPYPKQMQLLAKNPEILVATPGRLIDHMESGKIDFSELEILVLDEADRMLDMGFIDDIEKIVDATPATRQTMLFSATLDGVVGNMARRITNNPMIIQIAGSTAKHENISQRVHFVDDMSHKNRLLDHLLRDETLDQAVIFTATKRDADTIADRLNIAGFAAAALHGDMHQGARNRTLDGLRRGQVRVLVATDVAARGIDVPAITHVFNYDLPKFPEDYVHRIGRTGRAGRNGVAISLVNHAESMNVKRIERFTKQLIPVEVVEGFEAKRSASPRSSAKPGGWKPGDGRSNSNSRNGNGGGNTGSGYAGNKPAQRTFSKPAAPSRDGGGGFNKEAGGYKGGNRSSDTTRRSFGDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTV8</accession>
    <name>A0A2S9GTV8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HDOD domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4145</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000028">
        <property type="protein sequence ID" value="PRC91144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91144">
        <property type="protein sequence ID" value="PRC91144"/>
        <property type="gene ID" value="S2091_4145"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013976">
        <property type="entry name" value="HDOD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08668">
        <property type="entry name" value="HDOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51833">
        <property type="entry name" value="HDOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HDOD" evidence="1">
        <location>
            <begin position="21"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="278" mass="30082" checksum="B1AEACBF552F2669" modified="2018-07-18" version="1">MDRLEAFRSIAAQASRGEISFSANINATLKIKQLLDDPDAHLASATKLVLADPLFSARAVAVANSVAYNRTDTKITNVTTAVMRLGFATLRSLAMSLIVRQMNDGFSNPVIRKKSAELWEHTARVAALAQVIARRMTKVDPDAALFAGIVHEVGGFYLLSRAEEFPGLLDGELEGWMEYGEKIIGRGVLKALEIPETICEAIEQVWVGVGAQPPVTLGDVLTLANDLAGTFSPLQSPTELAIRDTDSQFDFRIGDETLTSIIEDAAEQIESLRVALLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GU66</accession>
    <name>A0A2S9GU66_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Iron-binding protein IscA</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Iron-sulfur cluster assembly protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_4026</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the HesB/IscA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000026">
        <property type="protein sequence ID" value="PRC91241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91241">
        <property type="protein sequence ID" value="PRC91241"/>
        <property type="gene ID" value="S2091_4026"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.300.12">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000361">
        <property type="entry name" value="FeS_biogenesis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016092">
        <property type="entry name" value="FeS_cluster_insertion"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017870">
        <property type="entry name" value="FeS_cluster_insertion_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035903">
        <property type="entry name" value="HesB-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011302">
        <property type="entry name" value="IscA_proteobacteria"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01521">
        <property type="entry name" value="Fe-S_biosyn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89360">
        <property type="entry name" value="SSF89360"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02011">
        <property type="entry name" value="IscA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00049">
        <property type="entry name" value="TIGR00049"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01152">
        <property type="entry name" value="HESB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe-S_biosyn" evidence="5">
        <location>
            <begin position="1"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00014591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00032050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01521"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC91241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="107" mass="12003" checksum="E461FD3124F795AC" modified="2018-07-18" version="1">MAITLTEKAARHVTRYMERRGKGIGLRFGVRTTGCSGMAYKLEYVDEIGSEDQVFESFGVKVFVDPKSLTYIDGTELDFAREGLNEGFKFNNPNVKDECGCGESFRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GU69</accession>
    <name>A0A2S9GU69_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Response regulator of the LytR/AlgR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_4039</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000026">
        <property type="protein sequence ID" value="PRC91254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91254">
        <property type="protein sequence ID" value="PRC91254"/>
        <property type="gene ID" value="S2091_4039"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007492">
        <property type="entry name" value="LytTR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04397">
        <property type="entry name" value="LytTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00850">
        <property type="entry name" value="LytTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50930">
        <property type="entry name" value="HTH_LYTTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="4"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="HTH LytTR-type" evidence="3">
        <location>
            <begin position="166"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC91254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="278" mass="31585" checksum="DA9B8D2765D76AC8" modified="2018-07-18" version="1">MIPKIFILDDEAPARQRMRTLLSDIFEQCPTNVVGEAEHAQAALDAIAVCKPDIVLLDVQMPGISGIEFARHMLQNTQMQAAPIVIFVSAHDAYALQAFEVHAFDYLLKPVRAQRLQEAILRAVRLRNKISETSIEDSLDTSKNQHSTQLENLDLPTALPAKRQYFSVMERGRILLVSVKDVLYIKAEQKYLTLHTASQQHLIEESLQAIELEMPSVYVRIHRNTLIARAALVGVERGMELDEQTGKMTEAWQVILRDCKERLPISRRLWPTIKALVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GU81</accession>
    <name>A0A2S9GU81_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3966</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000025">
        <property type="protein sequence ID" value="PRC91295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91295">
        <property type="protein sequence ID" value="PRC91295"/>
        <property type="gene ID" value="S2091_3966"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="84" mass="9283" checksum="A0A71DFFB19C023A" modified="2018-07-18" version="1">MKKSLLVAAAVLTIVVGGAIAKEVKDWHDIHDAHEHTMQAIHEMERARAANHYDMAGHGAKAEELLRQAEHEIHESIEAAKGEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUP3</accession>
    <name>A0A2S9GUP3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3833</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000023">
        <property type="protein sequence ID" value="PRC91418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91418">
        <property type="protein sequence ID" value="PRC91418"/>
        <property type="gene ID" value="S2091_3833"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="22"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="77" mass="9320" checksum="0F800D4E0B6C81CA" modified="2018-07-18" version="1">MDFTFIDIPHRRNIDFDESTFIPFYCCYLFGISYSPIYNTIISISFVRWRTYNNLYITYCSSVKTELIPLLYQFKSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUX0</accession>
    <name>A0A2S9GUX0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3861</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000023">
        <property type="protein sequence ID" value="PRC91446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91446">
        <property type="protein sequence ID" value="PRC91446"/>
        <property type="gene ID" value="S2091_3861"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031917">
        <property type="entry name" value="Pilus_assem_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032636">
        <property type="entry name" value="Pilus_assem_E-set-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15976">
        <property type="entry name" value="CooC_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16967">
        <property type="entry name" value="TcfC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TcfC" evidence="2">
        <location>
            <begin position="341"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="domain" description="CooC_C" evidence="1">
        <location>
            <begin position="797"/>
            <end position="887"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF15976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="922" mass="99211" checksum="F444471728068884" modified="2018-07-18" version="1">MLLMCSLWEKVLNALSLSCFEKKKLLVAPFSEQFGRHFCLLSTFLFVQAFPVFAAELDENSTSASEVTPTNSPAVLANFTDKALGKDAFPPEFFALLQAGVEVPFLLKTPQGAEEVGKATLRHTGDFLTIDHLSVGNSKVTAEYQALIEQQYGKPIHYQQCSRTALDGAATDKQNKNHLHSDTSDKNAGSDPAAAIGLCFDVMTFELIGDLPQEAYSQEARLRITALPDSTEKNLSGILNYNGSMVRLSGQNPDGYFRAKSVTSYGVNNFTLDGDVRANQPGDLYEARFSHDYQGVNVSAGYLSLWAMSDLGRISYANSGKFIGVIAGNKGRSEKTDTSLSKNPIYVFMPASGQVSIYRDGKLLNVQQVALGNQEVDTSALPGGNYLARVDVIVNGQVVSSKEEMVYKMSSSIGAGNQYQFFAGNYQNTYDGTSTHLVGASGQYNLPWVDLSASVYSYGSLMVIEPGFQKNFSHGSISGQFGVTSDGSHNGTLSSSLSLGSGSVWGMLDYARKGKPESAMTDRNFASLGGTFDLQNTFNLSKSSQITGSVSLDRQNNNRISRLDFSQSIYRNHWVEARLNAGKYWQTHQQDFDNNYTEIGLGNSMPSSAGNLQQSYYVGVNFTFSFGTGGIDYSRSLNSEMIGVNAAWTPKNIDGLDHLGTNVSRTRSLDDPNADISSNINVRANGRNSIFAWDAVVGSNSLNKGVDVTGGMSGSAGWNKGGFGMTNSQADAGILVKVDDEARGQLDLMVNGGSNLLENSTSFVPAPAFSTASMAVRSSAKSPENYDIQNSEQDFVLYPGNVGLLSPKLKRLVTVFGVLTENGQPKPGVVLSNHIGTATTDEDGGFSVDVDSVNPSVSYEVAKNQSCQIDFDLSAAKGAMWVNEVFCPSMKPNGKQLYEAAKPDMQTAIPAAESVVGSVFSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUZ3</accession>
    <name>A0A2S9GUZ3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">YqjK-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3663</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000021">
        <property type="protein sequence ID" value="PRC91547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91547">
        <property type="protein sequence ID" value="PRC91547"/>
        <property type="gene ID" value="S2091_3663"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025612">
        <property type="entry name" value="YqjK"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13997">
        <property type="entry name" value="YqjK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="95" mass="10506" checksum="328FDD71EE7BE0B9" modified="2018-07-18" version="1">MSRTKQLAMRRSILVAECALQRTTLAAQSHALGRITGWISASNGLVERLKNMPGWVSALLAGMLVLMPGRAVSLARNGLMIWQIWRNLKSNMDSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GV47</accession>
    <name>A0A2S9GV47_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Holliday junction ATP-dependent DNA helicase RuvA</fullName>
            <ecNumber evidence="8">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">ruvA</name>
        <name evidence="10" type="ORF">S2091_3696</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>ATP + H2O = ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="8">Forms a complex with RuvB.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the RuvA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="8"/>
    <dbReference type="EMBL" id="PUGF01000021">
        <property type="protein sequence ID" value="PRC91580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91580">
        <property type="protein sequence ID" value="PRC91580"/>
        <property type="gene ID" value="S2091_3696"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009379">
        <property type="term" value="C:Holliday junction helicase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009378">
        <property type="term" value="F:four-way junction helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009432">
        <property type="term" value="P:SOS response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd14332">
        <property type="entry name" value="UBA_RuvA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00031">
        <property type="entry name" value="DNA_helic_RuvA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013849">
        <property type="entry name" value="DNA_helicase_Holl-junc_RuvA_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003583">
        <property type="entry name" value="Hlx-hairpin-Hlx_DNA-bd_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000085">
        <property type="entry name" value="RuvA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010994">
        <property type="entry name" value="RuvA_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011114">
        <property type="entry name" value="RuvA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036267">
        <property type="entry name" value="RuvA_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07499">
        <property type="entry name" value="RuvA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01330">
        <property type="entry name" value="RuvA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00278">
        <property type="entry name" value="HhH1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46929">
        <property type="entry name" value="SSF46929"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47781">
        <property type="entry name" value="SSF47781"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00084">
        <property type="entry name" value="ruvA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6 8" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="8" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 8 10" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 8" id="KW-0742">SOS response</keyword>
    <feature type="domain" description="HhH1" evidence="9">
        <location>
            <begin position="73"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="domain" description="HhH1" evidence="9">
        <location>
            <begin position="108"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC91580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="192" mass="20303" checksum="742DA420DBC90D33" modified="2018-07-18" version="1">MIGRIAGVLLEKNPPQILLDCNGVGYEIDVPMSTFYNLPSLGEKVVLHTHLAIREDAHVLFGFSNHEERATFKQLIKISGVGARTALSILSGMSVADLAQAITLQEAGRLIKVPGIGKKTAERLLLELKGKLGANIAHGVGEVAAPDASSDILNALIALGYSDKEALMALKLLPKDCGVSDGIKLALKSLSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GV84</accession>
    <name>A0A2S9GV84_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Pseudouridine synthase</fullName>
            <ecNumber evidence="3">5.4.99.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_3580</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Responsible for synthesis of pseudouridine from uracil.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>a uridine in RNA = a pseudouridine in RNA</text>
            <dbReference type="Rhea" id="RHEA:48348"/>
            <dbReference type="Rhea" id="RHEA-COMP:12068"/>
            <dbReference type="Rhea" id="RHEA-COMP:12069"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the pseudouridine synthase RluA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.-" evidence="3"/>
    <dbReference type="EMBL" id="PUGF01000020">
        <property type="protein sequence ID" value="PRC91642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91642">
        <property type="protein sequence ID" value="PRC91642"/>
        <property type="gene ID" value="S2091_3580"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120159">
        <property type="term" value="F:rRNA pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000455">
        <property type="term" value="P:enzyme-directed rRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd02869">
        <property type="entry name" value="PseudoU_synth_RluA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006225">
        <property type="entry name" value="PsdUridine_synth_RluC/D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006224">
        <property type="entry name" value="PsdUridine_synth_RluC/D_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006145">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00849">
        <property type="entry name" value="PseudoU_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01479">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00363">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00005">
        <property type="entry name" value="rluA_subfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01129">
        <property type="entry name" value="PSI_RLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S4" evidence="4">
        <location>
            <begin position="57"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR606225-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU362028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC91642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="351" mass="38240" checksum="4C567FAB66E088DD" modified="2018-07-18" version="1">MGLTVIATIPSNLHGSEIHPDELTGDLADEFAEESEASYAFNATPIIFKLDEDVCGDRLDKVIARLIPQFSRSRLQQWIVSGHVTVDGVAGRGKMTVLGGEEVIVYPQPAPEDNAYSPENMALDIVFEDKSMLVINKPAGLVVHPAAGNWSGTLLNGLLHHFPAISGVPRAGIVHRLDKDTSGLMVVAKTLEAQTDLVRQLQARTVKREYLALVWGRPNLSGTIDSPMARHPRDRIKMAVSDSPSAKPAVTHFQRIAIGVLDGKPVSLVECQLETGRTHQIRVHMAHLGFPLVGDVLYGKQHLASYFNRQALQARRLGLLHPKNQKECSWQVGLADDIAALLVSAGIEYAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVI9</accession>
    <name>A0A2S9GVI9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3614</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000020">
        <property type="protein sequence ID" value="PRC91676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91676">
        <property type="protein sequence ID" value="PRC91676"/>
        <property type="gene ID" value="S2091_3614"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015585531" evidence="2">
        <location>
            <begin position="20"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="51"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="71" mass="8035" checksum="474746756C2780D3" modified="2018-07-18" version="1">MRHILIFSLLLTLVCGLSACGKTDNKAVEEKPAFDIAPQRAQLQKAKDLEKKMQEDAENQRKVIELQTNPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWE7</accession>
    <name>A0A2S9GWE7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3184</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AHA1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000016">
        <property type="protein sequence ID" value="PRC92049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92049">
        <property type="protein sequence ID" value="PRC92049"/>
        <property type="gene ID" value="S2091_3184"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013538">
        <property type="entry name" value="Activator_of_Hsp90_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08327">
        <property type="entry name" value="AHSA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="135" mass="15467" checksum="A3E7F6C44A209E74" modified="2018-07-18" version="1">MMQTDETKTLIVEREMPHPLEKIWRALTQGPLIEEWLMKNDFQPIVGHRFDLRADWGVVHCHVLAVEPNKALSYAWEALGLKSVVTWTLTPTSTGTHLRMEQSGFRPDQQQAYEGAKYGWQKFFAALDRVVGGLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWU4</accession>
    <name>A0A2S9GWU4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Chromate transport protein ChrA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_3109</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92193">
        <property type="protein sequence ID" value="PRC92193"/>
        <property type="gene ID" value="S2091_3109"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015109">
        <property type="term" value="F:chromate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003370">
        <property type="entry name" value="Chromate_transpt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02417">
        <property type="entry name" value="Chromate_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="18"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="84"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="119"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="147"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="172"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC92193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="191" mass="20259" checksum="5B183C2C0EE0BF83" modified="2018-07-18" version="1">MLDPLPHQHPAPQSIADLFYSFTLIALQGFGGVLAIIQRELVDKKGWLTREEFIEEWAVAQIMPGPNVVNLSLMVGARYFGLRGALAALAGMLCVPLIIVVILGVLYAEFATHPGVSGAIRGMSAVAAGLIIATGLKLFAGLKSNPLGKTLCITLGLMCFGCIALLRWPLLHVLLGLGPIACIAAYRALKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GX01</accession>
    <name>A0A2S9GX01_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acetyltransferase (GNAT) domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3147</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92231">
        <property type="protein sequence ID" value="PRC92231"/>
        <property type="gene ID" value="S2091_3147"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004343">
        <property type="term" value="F:glucosamine 6-phosphate N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006048">
        <property type="term" value="P:UDP-N-acetylglucosamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039143">
        <property type="entry name" value="GNPNAT1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13355">
        <property type="entry name" value="PTHR13355"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13673">
        <property type="entry name" value="Acetyltransf_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="2"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="138" mass="14757" checksum="DC7965D8F4EA25BA" modified="2018-07-18" version="1">MNNTEAYTAERLTPSVATYCHLRSAAGLSAKTEEAARKGLKGTLFAVQLLFQGEPIGMGRVIGDGGCFYQVVDIAVLPEHQGKGLGKQIMHEIMVYLEAHAPKSAYVSLIADGKARDLYAQFGFAPTAPKSIGMAIKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXE6</accession>
    <name>A0A2S9GXE6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2767</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92392">
        <property type="protein sequence ID" value="PRC92392"/>
        <property type="gene ID" value="S2091_2767"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="85" mass="9320" checksum="4FCD0DF51D7B09A2" modified="2018-07-18" version="1">MKYATILFVATTTLSGCSLISGLSNSCMENKTDGSKICTMIDSNQNITTRSIERDHRLFISTCSNGNCTEFKEVDGKTVDSINQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GY44</accession>
    <name>A0A2S9GY44_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Formylglycine-generating sulfatase enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2683</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92628">
        <property type="protein sequence ID" value="PRC92628"/>
        <property type="gene ID" value="S2091_2683"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042095">
        <property type="entry name" value="SUMF_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="SSF56436"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="237" mass="25674" checksum="43F3CF0CD7522FC4" modified="2018-07-18" version="1">MDAALEQEAEVVNEYVTVPETTLPNGTVVPAFKVGKYITGRENDALAITATAAPWVEINFADAQSEAEKAGLKLITETQYLAIAHNIAQQAINWTSGIVGEGSIFQGIRDYSVDEAQPGTYESEDADERRWHELSTGERVFDFAGNCYTWIFDDVQGDENGIVAKAFAADSPSITTAPAPSYTKGMGWYPSAGCDLSSYALVRGGCWSSGDYAGVFLLNRDSPDYGNDDVGFRCTFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GY46</accession>
    <name>A0A2S9GY46_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HTH cro/C1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2697</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92642">
        <property type="protein sequence ID" value="PRC92642"/>
        <property type="gene ID" value="S2091_2697"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="2">
        <location>
            <begin position="7"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="163"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="183" mass="19895" checksum="6F25572F41544323" modified="2018-07-18" version="1">MSIGTRIKELRTLKKISQAALGKRVGISAPAISDLESGKSVSSTKLPMIASVLGVNALWLETGRGKPNLEHVEPIEVRTKFHPDIEAVIQLMESTDGRGRNKILNAAQDALELHQAHNIAIKRSNEQLTASKDKTDQLNREAELLAKFRQSTDAGKSLILTISDEAPKETEVPMAPSKKLNAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GY57</accession>
    <name>A0A2S9GY57_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2704</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92649">
        <property type="protein sequence ID" value="PRC92649"/>
        <property type="gene ID" value="S2091_2704"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="122" mass="13900" checksum="6B89EE4990294F31" modified="2018-07-18" version="1">MSAFIVFGMNEDQKNLAVARAKKAISGLVKRTEKTMKRELTEEEYSILLNEELPIYILKAFKPVSAPLSAPQFCRDYIAAAKVCKFDCEMKIMMRGTITKIVKRKRGGAVEVSRMGWVEYRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GY75</accession>
    <name>A0A2S9GY75_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HeH/LEM domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2724</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92669">
        <property type="protein sequence ID" value="PRC92669"/>
        <property type="gene ID" value="S2091_2724"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.720.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025856">
        <property type="entry name" value="HeH/LEM_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036361">
        <property type="entry name" value="SAP_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12949">
        <property type="entry name" value="HeH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HeH" evidence="1">
        <location>
            <begin position="46"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="79" mass="8263" checksum="14C6A7315B91F740" modified="2018-07-18" version="1">MSDACETVKIVSPITDENPLGFIVINKCDLTDADNLFGESVATAVLTFPQLKDALTAKGVTIPNGAKKADLQALLDANS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GY83</accession>
    <name>A0A2S9GY83_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2715</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92660">
        <property type="protein sequence ID" value="PRC92660"/>
        <property type="gene ID" value="S2091_2715"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="166" mass="18621" checksum="B8F1B3767214E598" modified="2018-07-18" version="1">MSIGQMYAKSVQSSNLKDDAYHHDTDKLAAMALSKRLGSELFRVKYANDATSYPRLLEEWICIVRNKAIHRKWPVHVRASYIAKAALDYWLNPVCQVCTGRGFDSKINKSGEYEHDCKPCGGSGRKSVSGEANLLQFIIDMVEALDDMERISGGLAIKRLADAFDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYP9</accession>
    <name>A0A2S9GYP9_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Putative glutamate--cysteine ligase 2</fullName>
            <ecNumber evidence="2">6.3.2.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Gamma-glutamylcysteine synthetase 2</fullName>
            <shortName evidence="2">GCS 2</shortName>
            <shortName evidence="2">Gamma-GCS 2</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2516</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 2">
            <text>ATP + L-cysteine + L-glutamate = ADP + gamma-L-glutamyl-L-cysteine + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13285"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58173"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.2"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.2" evidence="2"/>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92786">
        <property type="protein sequence ID" value="PRC92786"/>
        <property type="gene ID" value="S2091_2516"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004357">
        <property type="term" value="F:glutamate-cysteine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042398">
        <property type="term" value="P:cellular modified amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01609">
        <property type="entry name" value="Glu_cys_ligase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006336">
        <property type="entry name" value="GCS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014746">
        <property type="entry name" value="Gln_synth/guanido_kin_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011793">
        <property type="entry name" value="YbdK"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04107">
        <property type="entry name" value="GCS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55931">
        <property type="entry name" value="SSF55931"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02050">
        <property type="entry name" value="gshA_cyan_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 3" id="KW-0436">Ligase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00029283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="371" mass="42087" checksum="8018CBAD85DBD4CB" modified="2018-07-18" version="1">MALGPFSESRSLTMGIELELQLVNLHDYDLVGSAEDLLRDVARQKLDMDVKPEMTLSMIEMATGICENYTDALHQLTDIRDVLVASADRLNIGICGGGTHSFQHWGDRKIFDKPRFQYLSELYGYLAKQFTIFGQHVHIGCPGPDVALYLLHGLSRFIPHFIAMSASSPFVQSDDTGFQSARLNSVFAFPLSGRAPFVETWAEFEVYFEKMTATGVVKGMKDFYWDIRPKPEYGTIEVRVMDTPLTVLRAAQIAAYIQSVARYLMIERPFRLAEDDYLVYTFNRFQACRFGYAGTYVDPCTHEHRTIAEDILETFKHIEQHAIELRADEACRALMADVVAGQNDAAVLRAAWQTTHSLPEVVQAQCERWRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYT8</accession>
    <name>A0A2S9GYT8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HDIG: uncharacterized domain HDIG</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2288</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92871">
        <property type="protein sequence ID" value="PRC92871"/>
        <property type="gene ID" value="S2091_2288"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008081">
        <property type="term" value="F:phosphoric diester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021812">
        <property type="entry name" value="DUF3391"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037522">
        <property type="entry name" value="HD_GYP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006675">
        <property type="entry name" value="HDIG_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11871">
        <property type="entry name" value="DUF3391"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00277">
        <property type="entry name" value="HDIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51832">
        <property type="entry name" value="HD_GYP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HD-GYP" evidence="1">
        <location>
            <begin position="137"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="411" mass="46244" checksum="EE546341D89B2B5F" modified="2018-07-18" version="1">MLKKITIQQLRQGMYIQEFCISWIAHPFWKQSFLVDTEARYHSVKSSNVTELIINTDKGVDVLAEREPKLAPVKHSLEIAKPTPELIHKQAVSMDMELEHASRVVARSKQAVMSMFHEVRMGNAANMESMQPLVEEITDSINRNAGALIGLARLKNKDEYTYMHSIAVCALMIALAKQLNLSSDEIKEAGMAGLLHDIGKMTVPTKILNKPGKLTESEFEMVKQHPLAGYQLLLRAKAISPVALDVCLHHHERFDGTGYPYRYAGDKISLMARMSAVCDVYDAVTSNRPYKKGWCPSESIHKMAEWSGKHFDDQIFQAFVRSIGIYPAGTLVMLETGRMGVVVEQNDVSLLLPMVRVFFSSKSMTYIVPVLLDLSQPGKQDKIVSRELVSKWGFKNIDAYWLGEAGIKQEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYY9</accession>
    <name>A0A2S9GYY9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Tetrapyrrole (Corrin/Porphyrin) Methylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2330</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92913">
        <property type="protein sequence ID" value="PRC92913"/>
        <property type="gene ID" value="S2091_2330"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1010.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000878">
        <property type="entry name" value="4pyrrol_Mease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035996">
        <property type="entry name" value="4pyrrol_Methylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014777">
        <property type="entry name" value="4pyrrole_Mease_sub1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00590">
        <property type="entry name" value="TP_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53790">
        <property type="entry name" value="SSF53790"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TP_methylase" evidence="1">
        <location>
            <begin position="8"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="270" mass="29992" checksum="9BE23F1311F9604E" modified="2018-07-18" version="1">MIQKQAGKLVCVGTGMRMAGQLTPLSKSYIESFDIVFAAVPNIFTREWLKGVAKEFVCILDHYEDTKIDGKTRRDTYRRMADTILHEVRAGKRVCAAFYGHPGIFACISHMAIADARAEGFAAHMEPGISALDCLVADLGIDPGSTGMQSMEATQFMIFQRVVDPTALFVIWQIGICGDLTLKRFDTEPAHLQIIVDKLARSYSLDHEVILYEAATHALEQTRAEKIRLGDLPQASLKQHTTLVIPAAEKLQYDANVIAQLQDLERLRVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZ57</accession>
    <name>A0A2S9GZ57_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">PLD-like domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2407</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92990">
        <property type="protein sequence ID" value="PRC92990"/>
        <property type="gene ID" value="S2091_2407"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019637">
        <property type="term" value="P:organophosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025202">
        <property type="entry name" value="PLD-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001736">
        <property type="entry name" value="PLipase_D/transphosphatidylase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13091">
        <property type="entry name" value="PLDc_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50035">
        <property type="entry name" value="PLD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015779947" evidence="1">
        <location>
            <begin position="27"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="domain" description="PLD phosphodiesterase" evidence="2">
        <location>
            <begin position="118"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="domain" description="PLD phosphodiesterase" evidence="2">
        <location>
            <begin position="265"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="330" mass="35413" checksum="611C20469426B038" modified="2018-07-18" version="1">MINRNSFKNSALTLMLSSFVLLSANAVEATTSVTRTLVTEPSQGLTSIYDLINSAKKTIDMTMYELTDTTAENLLVQAASNGVTVRVILDQDNEKSNNQAAYTLLAAHGVQVHWANTAYTYTHKKTITVDGTTAAIMTLNLSSQYYSTSRDFAVIENDANDIKAIEAVFNADFANKAITPALGDDLVWSPTNSQSVLLALINGAKYNLKVENEEMDDTAIAAALASAAKRGVQVEVTMTANSDYATELNQLKTAGVKIATYAATAPLYIHAKVIIADFGYTAAKAYMGSENFSNTSLNKNRELGLTLTDSDILSSLNATLTSDFKGGTAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZ71</accession>
    <name>A0A2S9GZ71_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 6">Phosphate-binding protein PstS</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_2110</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 6">Part of the ABC transporter complex PstSACB involved in phosphate import.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 6">The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the PstS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93024">
        <property type="protein sequence ID" value="PRC93024"/>
        <property type="gene ID" value="S2091_2110"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042301">
        <property type="term" value="F:phosphate ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035435">
        <property type="term" value="P:phosphate ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005673">
        <property type="entry name" value="ABC_phos-bd_PstS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024370">
        <property type="entry name" value="PBP_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12849">
        <property type="entry name" value="PBP_like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002756">
        <property type="entry name" value="PstS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00975">
        <property type="entry name" value="3a0107s03"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0592">Phosphate transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015547249" description="Phosphate-binding protein PstS" evidence="7">
        <location>
            <begin position="28"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="domain" description="PBP_domain" evidence="8">
        <location>
            <begin position="29"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR002756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC93024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="349" mass="37112" checksum="345CBF8C2C73F3B2" modified="2018-07-18" version="1">MSISKLIKSLIIVVGASSVFAASAVHAEDMTGAGATFPYPIYAKWADAYKKATGNGLNYQSVGSGAGIKQIKNKTVDFGASDMPLKAEELDAAGLIQFPAIMGGLVPVVNLDGIAAGKMKLTGDVIAGIYLGKITKWNAPEIVALNPDIKLPATDITVVHRSDGSGSTFLWTDYLSKVNAEFKSTIGSGTAVKWPVGLGGKGNEGVAASVLNIKGTIGYVEYAYVKKNKMIYAQLKNRDGNFVEPGDDSFKAAAAGAEWSKVPGYNIVLTNQTGKASWPITGASFILMYKQQADSTKGREVLKFFDWAFKNGEAMAAELDYVAMPSAVTKLVQETWKAELKDTAGKQIW</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZ85</accession>
    <name>A0A2S9GZ85_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Lipoprotein-releasing system ATP-binding protein LolD</fullName>
            <ecNumber evidence="7">7.6.2.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">lolD</name>
        <name evidence="9" type="ORF">S2091_2106</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">The complex is composed of two ATP-binding proteins (LolD) and two transmembrane proteins (LolC and LolE).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell inner membrane</location>
            <topology evidence="7">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.6.2.-" evidence="7"/>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93020">
        <property type="protein sequence ID" value="PRC93020"/>
        <property type="gene ID" value="S2091_2106"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044873">
        <property type="term" value="P:lipoprotein localization to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042953">
        <property type="term" value="P:lipoprotein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03255">
        <property type="entry name" value="ABC_MJ0796_LolCDE_FtsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015854">
        <property type="entry name" value="ABC_transpr_LolD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011924">
        <property type="entry name" value="LolD_lipo_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017911">
        <property type="entry name" value="MacB_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24220:SF654">
        <property type="entry name" value="PTHR24220:SF654"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02211">
        <property type="entry name" value="LolD_lipo_ex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="1 7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-1278">Translocase</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="8">
        <location>
            <begin position="13"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="49"/>
            <end position="56"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU367068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC93020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="233" mass="25261" checksum="F2A8EF0F5558A9B0" modified="2018-07-18" version="1">MSELQKMNLDIVLECSGVGKTYGDGEFAVPVLQGVNLQVKRGERVAIVGASGTGKSTLLHVLGGLDNASTGWVKLQGNDFSKMTELQRGNLRNSSLGFVYQFHHLLPEFSALDNVAMPLMIRRMPHAQAQSQAQRMLEQVGLGHRVSHVPGELSGGERQRVALARALVTKPACVLADEPTGNLDRQNAQHIFDAMLDLAHSSGTAFVIVTHDLELASRCDRILSLTQDGLDLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZ87</accession>
    <name>A0A2S9GZ87_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Response regulator receiver domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2135</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93049">
        <property type="protein sequence ID" value="PRC93049"/>
        <property type="gene ID" value="S2091_2135"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="10"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="129" mass="14488" checksum="A483DEF44419182E" modified="2018-07-18" version="1">MTTETSDLFSLLIVDDSRVSRMMIRAFVLDKNPTWQITEASSGDEAMKLVEQHRFDFCTMDINMPGTLGTVATEQILLKYPHMRIAVFSANIQECLRTHAAKLGARFVAKPVTEKSVEQAITFFKNADG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZA4</accession>
    <name>A0A2S9GZA4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">TPR repeat</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2123</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93037">
        <property type="protein sequence ID" value="PRC93037"/>
        <property type="gene ID" value="S2091_2123"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015736614" evidence="2">
        <location>
            <begin position="20"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="335"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="387" mass="44038" checksum="8B0FA469E0EAA9EA" modified="2018-07-18" version="1">MKIVYLVFIAWLLTGCASQLTKTPPVNDLFHDEMFVAASIPINAADALAISQPMRDFAQAKLSHRQGHLNMEDRRRALIEALYNGGELHLEYDSILTRTAAESFDAKSGNCLSLVLMTAAMAKELHLPIRYQTVIGVTDWSRSDSFFVAVGHVNLLMDEIPKESNMKTVATQAMLIDFLPPEQANVLVTREIEEKTVLAMYLNNRAVESLIQGKNDDAYWWAREALLQDREFFNAYVTLGVIYRTAHHPEIAELILERAAINEPDNTTILTNQILVLKDLGRVQEAKEKAARLLELDPHPLMSYYFQAQSEMSAGHFESARRLYEKEIARDPDHHEYELGLALVYFNLHDNENAMKHLKRAIELSPSKKMRGLYEEKLQRLKALGVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZB5</accession>
    <name>A0A2S9GZB5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phage portal protein, HK97 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2165</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93079">
        <property type="protein sequence ID" value="PRC93079"/>
        <property type="gene ID" value="S2091_2165"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006944">
        <property type="entry name" value="Phage/GTA_portal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006427">
        <property type="entry name" value="Portal_HK97"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04860">
        <property type="entry name" value="Phage_portal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01537">
        <property type="entry name" value="portal_HK97"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="392"/>
            <end position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="418" mass="46634" checksum="3BB441B3D291573F" modified="2018-07-18" version="1">MKLLNLFRAKTTPEAQSRPQASVGQLFDGLDDPDLLAFMRNGGGTASGAYVTASKALQNMALLRCVTLISESIGMLPLNLIERGDEKKYATTHPLYRLLKSRPNQWQTAYEFKSLMQLRLLLHGNAYARIIRSRDQIIQLIPIDPALVTPKLDDQWNMQYHYQRKNGETLILPASEIFHLRDLSDDGIVGLSRVKLAREAIGIALQAEKAAARLFKNGVMAGGALSSPDKLSDEAYTKLQASVEAKAGADNAGRWMILEEGLKAEQFANTAADAQHIENRNHQIEEIARAMGVPRPLLMMDDTSWGSGIEQLGIFFVQYSLQHWFTVWEQATERSLLTPEECGKYFIKFNERALLRGTLKDQADFFTKALGSGGQQPFMTANQVRELLDMSKDKSKHADELGTPLIKDKNVTTNPAKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZC0</accession>
    <name>A0A2S9GZC0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Chemotaxis protein CheC inhibitor of MCP methylation</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2134</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93048">
        <property type="protein sequence ID" value="PRC93048"/>
        <property type="gene ID" value="S2091_2134"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007597">
        <property type="entry name" value="CheC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028976">
        <property type="entry name" value="CheC-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04509">
        <property type="entry name" value="CheC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103039">
        <property type="entry name" value="SSF103039"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0145">Chemotaxis</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CheC" evidence="2">
        <location>
            <begin position="8"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04509"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="203" mass="22483" checksum="D4CCAF463A65F251" modified="2018-07-18" version="1">MDKLTDLQLDALSEVFNIGAGRAAASLSEIVNEEVKLSVPAVEICKSADLNAKALSLEQTQFGVVKQQFSGTFQAEASLLLTEENALEILRDMLGSQISIEELAEFEQEAMCELGNIILNACLSAMADMLDIQLESSLPTYNIYSSDEVISDIIETQDHGYVMILHIDLEIERRQINGRLIFLFSSSSLSMLRSKIDNFLQNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZD6</accession>
    <name>A0A2S9GZD6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2177</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93091">
        <property type="protein sequence ID" value="PRC93091"/>
        <property type="gene ID" value="S2091_2177"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="90"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="109" mass="12897" checksum="A0506DAC2EDA46E8" modified="2018-07-18" version="1">MCETTMKKFQLLTLFAEALFFCYFVWGALTTTHDKVLFLFNMGFLLIFLSGLYGDIFYYKDRFVRLKMSIPEIYKDAKTGKRSMTMVEHALLFLGFSFLAMSAYFKFFM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZH7</accession>
    <name>A0A2S9GZH7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="10">TonB-siderophor: TonB-dependent siderophore receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">S2091_2220</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93134">
        <property type="protein sequence ID" value="PRC93134"/>
        <property type="gene ID" value="S2091_2220"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015344">
        <property type="term" value="F:siderophore uptake transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0038023">
        <property type="term" value="F:signaling receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039423">
        <property type="entry name" value="TonB-dep_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010105">
        <property type="entry name" value="TonB_sidphr_rcpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32552">
        <property type="entry name" value="PTHR32552"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01783">
        <property type="entry name" value="TonB-siderophor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="3 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 10" id="KW-0675">Receptor</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="2 6" id="KW-0798">TonB box</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015493111" evidence="7">
        <location>
            <begin position="43"/>
            <end position="726"/>
        </location>
    </feature>
    <feature type="domain" description="Plug" evidence="9">
        <location>
            <begin position="89"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="8">
        <location>
            <begin position="292"/>
            <end position="725"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC93134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="726" mass="79551" checksum="4D7350D510592416" modified="2018-07-18" version="1">MPSIANSIHTPAYFLPPHLTLRPIALALTLALSVTAPAIAFAQQINSTDTETKLPEVLVLSNSEQQPTEKTDDYTVSKSNTATKLDLSLRETPQSVSVTTSTKMNDFKLDNINQVLAGTTGVTVEKVETDRTYYTARGFDIINFQYDGVGVPLVFGNQNGDLDTAIYDRVEVVRGANGLMSSTGNPSATVNFVRKRPTYDFQASGDVSYGSWDTRRIDADVSGALNSEKTVAARFVVAQQDGNSYLDRYKPSKSVLYGVIEANLSDNTLLTVGHNYQKNDSEGAMWGALPMYYSNGAPTNYGVNTNTSANWSYWDSEEQRTFAELNHHFSNDWQWKTTLSYNRLSTDGKLFYVYGTPVQSTGLGLYSYPSMYDSENKQTLLDSYGTGKYTLGGRQHDLTFGASWSRSTLDDISHYGQGVGTPLTATGAFDGSYPEPSFNASTAGSTYTDKRQSAYAATRLNLADDWKLLIGANYTDAQSTGIAYGISHQTSASATTPYTGLVYDLNKSVSAYASYTEIFNPQYQTNASGATLAPVTGKSYELGLKSDLIDRKLNASAALFRVEQQNAAEQAGYIGTTAYYRGINANSEGVEMELSGELAKGWQANLGYTAMTIKDQDGNPARTYVPKTLLRMATTYQVPQLEKLKIGASFNWQGKTSYVQSAPTNTTTQQGYGLLNLMMRYDISKQLSVSANINNVTNQKYISSLYWSQAYYGAPINGSISLNWKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZK8</accession>
    <name>A0A2S9GZK8_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Dihydrofolate synthase/folylpolyglutamate synthase</fullName>
            <ecNumber evidence="6">6.3.2.12</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Folylpoly-gamma-glutamate synthetase-dihydrofolate synthetase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Folylpolyglutamate synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">S2091_2247</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu). Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10-formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>(6R)-5,10-methylenetetrahydrofolyl-(gamma-L-Glu)(n) + ATP + L-glutamate = (6R)-5,10-methylenetetrahydrofolyl-(gamma-L-Glu)(n+1) + ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:51912"/>
            <dbReference type="Rhea" id="RHEA-COMP:13257"/>
            <dbReference type="Rhea" id="RHEA-COMP:13258"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:136572"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.17"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>10-formyltetrahydrofolyl-(gamma-L-Glu)(n) + ATP + L-glutamate = 10-formyltetrahydrofolyl-(gamma-L-Glu)(n+1) + ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:51904"/>
            <dbReference type="Rhea" id="RHEA-COMP:13088"/>
            <dbReference type="Rhea" id="RHEA-COMP:14300"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:134413"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.17"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>7,8-dihydropteroate + ATP + L-glutamate = 7,8-dihydrofolate + ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:23584"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17839"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57451"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.12"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5">Cofactor biosynthesis; tetrahydrofolate biosynthesis; 7,8-dihydrofolate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate and 4-aminobenzoate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the folylpolyglutamate synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.12" evidence="6"/>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93161">
        <property type="protein sequence ID" value="PRC93161"/>
        <property type="gene ID" value="S2091_2247"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00077">
        <property type="reaction ID" value="UER00157"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008841">
        <property type="term" value="F:dihydrofolate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004326">
        <property type="term" value="F:tetrahydrofolylpolyglutamate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046656">
        <property type="term" value="P:folic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046654">
        <property type="term" value="P:tetrahydrofolate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001645">
        <property type="entry name" value="Folylpolyglutamate_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018109">
        <property type="entry name" value="Folylpolyglutamate_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036565">
        <property type="entry name" value="Mur-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036615">
        <property type="entry name" value="Mur_ligase_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013221">
        <property type="entry name" value="Mur_ligase_cen"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11136">
        <property type="entry name" value="PTHR11136"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08245">
        <property type="entry name" value="Mur_ligase_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001563">
        <property type="entry name" value="Folylpolyglu_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53244">
        <property type="entry name" value="SSF53244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53623">
        <property type="entry name" value="SSF53623"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01499">
        <property type="entry name" value="folC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01011">
        <property type="entry name" value="FOLYLPOLYGLU_SYNT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0289">Folate biosynthesis</keyword>
    <keyword evidence="13" id="KW-0436">Ligase</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mur_ligase_M" evidence="14">
        <location>
            <begin position="52"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00000809"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00002714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00013023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00019357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00030048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00032510"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRNR" id="PIRNR001563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF08245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="PRC93161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="432" mass="47081" checksum="387F3CAA2177B0A6" modified="2018-07-18" version="1">MTNINTTSLSTLADWLAHLETAHPTVIELGLQRVGSVRDRLGIQFECPVIIVGGTNGKGSTCAMLESILMQGGYKVGLYTSPHLIHFNERARINGVSVADAEFVSAFEQVEEAKQDTSLSYFEFTMLACVKIFADAKLDVVILEVGLGGRLDAVNIFDADVAIITSVDIDHVEYLGDTREAIGFEKAGIFRAGRTAICSDPAAPLSLIEHANKIGADLWLFNRDFNYSGDKQQWNFAGRQHRRHSLAYPSLRGANQLLNASAALAALEALRTRLPLGAQEVRSGLVMVDLPGRFQVLPGVPAVVLDVAHNPHAAATLHQNLDNMGFHAYTYAVFGAMQDKDIAGVISQLKNQIDHWCLTDLPLPRGATAEHIQSLLTEQNVVNDKDHSIQCFENPASAYTYAVSKAGENDRIVVFGSFLTVAGVIQQRNEQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZK9</accession>
    <name>A0A2S9GZK9_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6">Carbamoyl-phosphate synthase small chain</fullName>
            <ecNumber evidence="6">6.3.5.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5 6">Carbamoyl-phosphate synthetase glutamine chain</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">carA</name>
        <name evidence="8" type="ORF">S2091_2226</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>2 ATP + H2O + hydrogencarbonate + L-glutamine = 2 ADP + carbamoyl phosphate + 2 H(+) + L-glutamate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:18633"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58228"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.5.5"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 6">Amino-acid biosynthesis; L-arginine biosynthesis; carbamoyl phosphate from bicarbonate: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="6">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 1/3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the CarA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.5" evidence="6"/>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93140">
        <property type="protein sequence ID" value="PRC93140"/>
        <property type="gene ID" value="S2091_2226"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00068">
        <property type="reaction ID" value="UER00171"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00070">
        <property type="reaction ID" value="UER00115"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004088">
        <property type="term" value="F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006207">
        <property type="term" value="P:'de novo' pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044205">
        <property type="term" value="P:'de novo' UMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006526">
        <property type="term" value="P:arginine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01744">
        <property type="entry name" value="GATase1_CPSase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01209">
        <property type="entry name" value="CPSase_S_chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006274">
        <property type="entry name" value="CarbamoylP_synth_ssu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002474">
        <property type="entry name" value="CarbamoylP_synth_ssu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036480">
        <property type="entry name" value="CarbP_synth_ssu_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035686">
        <property type="entry name" value="CPSase_GATase1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00988">
        <property type="entry name" value="CPSase_sm_chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01097">
        <property type="entry name" value="CPSase_sm_chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52021">
        <property type="entry name" value="SSF52021"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01368">
        <property type="entry name" value="CPSaseIIsmall"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 6" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="6" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CPSase_sm_chain" evidence="7">
        <location>
            <begin position="18"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="CPSase" evidence="6">
        <location>
            <begin position="1"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="6">
        <location>
            <position position="279"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="363"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00030197"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM01097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC93140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="392" mass="42166" checksum="F0F135F4D96F127E" modified="2018-07-18" version="1">MLPLSQSLPQSLCSGLDSPAILALSDGTLFHGYSIGATGSTIGEVVFNTAMTGYQEILTDPSYCQQIVTLTYPHIGNTGINSEDNESDKCQVAGLIIKDLPLLVSNFRSEQNLAAYLKAQNIVAIAGIDTRKLTRILREKGAQCGAILVGDDAQKAVQLAQSFAGLAGMDLAKVVSTKKTYEWRETEWVLGEGYGTQITPKFHVVAFDFGVKRNILRMLAERGCRVTVMPAETTAAEVLALNPDGVFLSNGPGDPEPCTYAIDAAKELIERGIPTFGICLGHQIMGIASGAKTLKMKFGHHGANHPVQDLVTKEVFITSQNHGFAVDEATLPANCKVTHVSLFDGSLQGFERTDKPAFCFQGHPEASPGPHEIAPLFDRFIALMNSEKNKNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZN7</accession>
    <name>A0A2S9GZN7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Redoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1932</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93194">
        <property type="protein sequence ID" value="PRC93194"/>
        <property type="gene ID" value="S2091_1932"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013740">
        <property type="entry name" value="Redoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08534">
        <property type="entry name" value="Redoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015448933" evidence="1">
        <location>
            <begin position="28"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="2">
        <location>
            <begin position="22"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="163" mass="18338" checksum="6F14646926C33028" modified="2018-07-18" version="1">MNRLVHLRSFVLVLITLAVLSACSKQAAPNVSFTDLKGTKISLEQLKGKVVMVNFWATSCTTCVAEMPEMIKTYEKYHAQGLEYVAIAMAYDPPNYVLNFTETRQLPFTVTLDFDGKLAQSFGDIKLTPTTFLIDKQGNIIKKYVGKPEFSQLHELIEAQLRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZS6</accession>
    <name>A0A2S9GZS6_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">3-dmu-9_3-mt domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1955</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93217">
        <property type="protein sequence ID" value="PRC93217"/>
        <property type="gene ID" value="S2091_1955"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028973">
        <property type="entry name" value="PhnB-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06983">
        <property type="entry name" value="3-dmu-9_3-mt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="3-dmu-9_3-mt" evidence="1">
        <location>
            <begin position="4"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="131" mass="14844" checksum="352E633DBE19C4ED" modified="2018-07-18" version="1">MQLSNYLFFTDSCEQALEFYTQCGLGHVVHTLQYGKDGMPVPIESLRGKIMHAKFEGPGVMFYASDNHDAEPMRGSAHMLTMDDRKQTENLFGYMAKNGVITTPLGMQPWGNFYGKLTDQFGVQWMFDCPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H042</accession>
    <name>A0A2S9H042_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2058</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93320">
        <property type="protein sequence ID" value="PRC93320"/>
        <property type="gene ID" value="S2091_2058"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021951">
        <property type="entry name" value="DUF3567"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12091">
        <property type="entry name" value="DUF3567"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="85" mass="9713" checksum="CAA77B4BB52D1B5A" modified="2018-07-18" version="1">MNLIYNSEQYSVVEFGADDDNEALRYGGYEITDKAVKREFFMGGMQAVTFRKDVSDLIASDPSLEEVDDFLGQYDPYMLQIVTVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0F6</accession>
    <name>A0A2S9H0F6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1817</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93430">
        <property type="protein sequence ID" value="PRC93430"/>
        <property type="gene ID" value="S2091_1817"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="304" mass="34484" checksum="39306C6430A28444" modified="2018-07-18" version="1">MNSHIEHSEINRINRSLDWLSTTLHQQLDDAANAWFVSQLAQLHNEANEAKLFKALGLAARYVGKSSLLFNEQEAAKLRRGFDPTYWSVDQAVRVAFLLTSFVHQPDEFSARLNRIADSAEINELIALYRGFALYPASAELEPRAREAIRSSMRPIFEAMAHRNPYPADIFDQAAWNQMIVKCFFMDSALWPIQGLEQRANPELARILVDLAHERWAAGRAINPELWRCVAPHADSTGLAALDRVMSSGSEPERIAVYWSLCDATSPQTKELQVLHQRCIQQDLSEKALAFQWNTLNPAQLETL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0G1</accession>
    <name>A0A2S9H0G1_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF4157 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1844</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93457">
        <property type="protein sequence ID" value="PRC93457"/>
        <property type="gene ID" value="S2091_1844"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025295">
        <property type="entry name" value="DUF4157"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13699">
        <property type="entry name" value="DUF4157"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4157" evidence="2">
        <location>
            <begin position="124"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="105"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="1052" mass="114358" checksum="6417BF9A702C0256" modified="2018-07-18" version="1">MSTATPLQPVKTETQQQHSSLSPQSTQLAPQADSKFIDNRPQTTALTIANTNINNSAQAKQLRAFSQIAQTAPRAKQFKAMSAMMNTPALKRVEEEETLQAKSMLENPAQRSEQGAPKPNNTGLPDNLKSGIESLSGMNIDHVKVHYNSPQPAQLNAHAYAQGSEIHVAPGQEQHLPHEAWHVVQQAQGRVKPTMQMKGGVPVNDDAGLEKEADVMGSKALQFKENHPAPGPVFQNQAAATGISSIQYVRKNQTDLIALTVGAFDAHRKAEQMDWANEAGFSKNDRETIWDILDWGTGGLAAFTLSDIITKAKKGTPEFNFLNIYCQSINGAVDGKPTIQLESLLDIDDAIKQGKWLSTLQATIGNDSHLKSTIPLDAFIQLIETETIATAFINYYTTCNPILETPTGDEVKAFVTLVKVEGAKISDYKTDLPDIRNLHKFEKASLDKLKADKGNKTKPLTLVLLSLFDHNGAFIRHAHVNKVIQNTNTNAYAIEGADEGKLTNLKDAGLAQIALTHGKDGKITQIMVAGHGSSKSIEVGGEKTVSGKSVKTGADVTIPDYKTKFDLEFDTKKGSFWTDFFAQAFDNMEAKDGLSPKILLRACLTGSNEIDLEKLKIVLVTEKGLDLTSADPTTDINQTKIRLAIKEQYEKHGSLVSVLGDKAKGKGITILGAQASISARETESVVPATGELGVIPATGIPLAQQDPHVAGTKINYVRSGKEPTGVIKAVIESWAIDKDDCFLKMAERVTDPVGTDDEFTIQLIFKTISAQYTKNILEANKFVNTAGNLHGIAEGRAECRASTLANDAMTQTHQSDFYPALLTKFKNQFAKLVIYEDWMQKDTSKRADFVDQLSNPAFTRTNVEKYLEAKLLDAHFSSIFTGSLGNERGRILLGLFGFIKNGQADCKTYLLTQKDVDGKLLATLTDELNGYNEDLLRGSLGLPVEAAPKIGGGGGILGAAPKAQKNIDVVSAFYVSPMRPTNYESNTVGSVRIRSGPAHNSPELESFFKNRTFIVVGEVKRIADDTSVGRYMVKQDAGTVGYVSKDAVKVKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0R5</accession>
    <name>A0A2S9H0R5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1843</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93456">
        <property type="protein sequence ID" value="PRC93456"/>
        <property type="gene ID" value="S2091_1843"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015716897" evidence="2">
        <location>
            <begin position="34"/>
            <end position="1119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="884"/>
            <end position="905"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="917"/>
            <end position="939"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="951"/>
            <end position="971"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="1119" mass="126220" checksum="65FD3B7C46CA75A9" modified="2018-07-18" version="1">MKRLFRYQRKITPLAFIQLFAGTLLVASNLCSAQVKIATVTSGATASQAASIDLDKKPTKPTATSTKKTVNITGYNQNIRQENFKGLSKTVVLTMQKQLESIYQSFPDWQRDYELKHEPLNDGIVGPITLSWLQRFAFSFKINSVGDYANEIVKNVDRIAQFGDRHRADLTILLSPEFEAWDSAEIDKLQTQDFQIRRQGSDKELIDLVNRFRGNRKTPPPASKPFVDESAYFNYSLNQNDLDLLGNKDQIVQILGPFKDKEFNSTEALRVAVKQAMGGREYFLNQIWPLIEKNAADFDGYLINDAALKKLKETSDFPAAVIDELRLQGTTYFKTKELFDAFLNEKFNDDTTTLSEGERQSIIEAAHVFDNVHLTEQSLSTIQNELKGNIQNTGAPAVVVRLLRQIKDVSYPEVSLFRSAAISKIEMGIGACKMNSSGSNPYVASLRIADEDFDLLEKELGALHAQTFNGKDTLEHLAELKKLRSQATQCDKATLQESHLWVEQIYQAYLALEIESIAKKRIPDEIATIHLKGGECGCALDEFSGVVYGFYPYWNNSKSTQTINFSVLNRVAYYGLSVDNVGDLQLGTTPLDVHDGLAEENQFLRIAHQYNSKVDWLIQKNDWNGDWKKYSRENKHAVFQALITNITQLLRTKLSDTASRLKPYTSLGISSRPTRGDGITLYFPNYPTDPDSALLFNDFYLTLRKELALDNIGVNILISQDVINDSGGNQQGAFNLTNMISLRKKTAQQDNSTDHTAVKEYLLILLDESSRNAKKQFRQDLDNVPGLNGIERVQFLRSIIPVLQFDNHNWQQLEDDIVYASDNFGGIGLWAPNFDNIAIPVTDLSQSCFHSQQIAVCLLKNYRPANLAERIPSGIERFTCVNRWGLQLTLTLFLFAAIVIVVLFIKYCEVQVFVKRYFLWILGCTLLPPISIFVLLLNYDPYLASLSKGNVPFIIAMGASAFIVIFGYLYLRSQRTVPQRQRAIPQRQGLGFPIITWIIENDERGFRWIIRNRGTGYAIIKRIEILLDGQAVADAKTALEAVLNSNKHLLWKSLPLIGKKMLPNEEVIGLAISDPASAIAFDKKLREHKLQVHITYCSANNDQWVSDGKEVSVVAAASY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0R7</accession>
    <name>A0A2S9H0R7_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NAD_binding_9 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1541</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93540">
        <property type="protein sequence ID" value="PRC93540"/>
        <property type="gene ID" value="S2091_1541"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038732">
        <property type="entry name" value="HpyO_NAD-binding"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13454">
        <property type="entry name" value="NAD_binding_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="domain" description="NAD_binding_9" evidence="2">
        <location>
            <begin position="10"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="467" mass="52881" checksum="4C8DD846C5F024BA" modified="2018-07-18" version="1">MTPNKITTIAIIGAGFSGVATALHLLKFELIKPIKVMLIDTIESFGKGLAYVTEDDNLVLNVPIGNMSLFSDQPNDFLDFCQKIDASLNSGSFVFRRIYGEYLQARLQQAKTDYPQNFIKLKDFVTGISQSNNCFILDLKSGSQVQADKVVMAFGHFQSKPLAEILPKNAINPAIDNNILLDSSWDICALDRLRTDQNVLILGAGHTAIDTLFRLVSKGVQRKIYLVSRHGYMPNGHRKAGEFIKLPILTKEIEIKVKEELKINPTIRTLFSTLRQLTKNHMAQQGNWRDVITSLRQITPEIWRGLSVKERRRFLTHIVHLWDVLRHRIAPVAMRRLDLLIASGKVEVIAGRIKQLNPDGNSINAVISLRRTNQNQEVKIGSVINCTGPNYDINRVINPLVRQLTELRILQQDELKLGFKVDEQYRCSHIQHLYYIGPMLKASHWEAIAVPELRTHALNLANILVES</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0T9</accession>
    <name>A0A2S9H0T9_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Glycerol-3-phosphate acyltransferase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Acyl-PO4 G3P acyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Acyl-phosphate--glycerol-3-phosphate acyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">G3P acyltransferase</fullName>
            <shortName evidence="10">GPAT</shortName>
            <ecNumber evidence="10">2.3.1.275</ecNumber>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Lysophosphatidic acid synthase</fullName>
            <shortName evidence="10">LPA synthase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">plsY</name>
        <name evidence="11" type="ORF">S2091_1606</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>an acyl phosphate + sn-glycerol 3-phosphate = a 1-acyl-sn-glycero-3-phosphate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:34075"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57597"/>
            <dbReference type="ChEBI" id="CHEBI:57970"/>
            <dbReference type="ChEBI" id="CHEBI:59918"/>
            <dbReference type="EC" id="2.3.1.275"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="10">Lipid metabolism; phospholipid metabolism.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Probably interacts with PlsX.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cell membrane</location>
            <topology evidence="10">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the PlsY family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.275" evidence="10"/>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93605">
        <property type="protein sequence ID" value="PRC93605"/>
        <property type="gene ID" value="S2091_1606"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00085"/>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043772">
        <property type="term" value="F:acyl-phosphate glycerol-3-phosphate acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01043">
        <property type="entry name" value="PlsY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003811">
        <property type="entry name" value="G3P_acylTferase_PlsY"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30309">
        <property type="entry name" value="PTHR30309"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02660">
        <property type="entry name" value="G3P_acyltransf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01207">
        <property type="entry name" value="G3P_acyltransf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00023">
        <property type="entry name" value="TIGR00023"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="1 10" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="2 10" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="6 10" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 10" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="9 10" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10 11" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="85"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="115"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="156"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC93605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="205" mass="21804" checksum="345F9F55943F7E73" modified="2018-07-18" version="1">MLNSVLAPLGFVIISYLIGSISFAVIVSKVFGLSDPRTYGSKNPGATNVLRSGNKAAAVLTLIGDAFKGWLAVWLAQALNLPEHVIALVALAVFLGHLWPVFFKFEGGKGVATAAGVLLGLNVWLGLGTLATWVVVAFCFRYSSLAALMAALFAPFYSALIFGTASPVFWAVCVMSALLIYRHQQNIRNLIAGKESRLGSKKTAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0V8</accession>
    <name>A0A2S9H0V8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="10">TonB-dependent Receptor Plug Domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">S2091_1599</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93598">
        <property type="protein sequence ID" value="PRC93598"/>
        <property type="gene ID" value="S2091_1599"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039426">
        <property type="entry name" value="BtuB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30069">
        <property type="entry name" value="PTHR30069"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="3 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 10" id="KW-0675">Receptor</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="2 6" id="KW-0798">TonB box</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015487048" evidence="7">
        <location>
            <begin position="24"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="domain" description="Plug" evidence="9">
        <location>
            <begin position="45"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="8">
        <location>
            <begin position="251"/>
            <end position="705"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC93598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="734" mass="80209" checksum="A82022A6FFCF8620" modified="2018-07-18" version="1">MKIRYPALLALTNFVMLYGATYASDDLVNIVNVEAAHYDQRHQETASIIVVNHDDLLRFGDTSLADALKRIPGISIGGAGSGLNGERAGEIRLHGLGGGYTQIMLNGVVAPNGFTLESLSPELIERVEIMPTASAELGAQGIAGTINIILRKSVAHPRREFKLELGEQDGARSSQLMPTLSGEVAGTLNNVDYVVVGTLSRTRLTTSTEIDTSAADGYPAAIDTLHRLTQEQKDSRTDNLNLTPRFTFHLSDDDSLTSQSYINAKHATVAQTDQDTTLLGTTSQYPASDRQFDLESTVLRSDLNWTHTFDEDTRFTLKAGASDSFRHSDFRFFGTDGSADGSGLHLVQAGINEYGITLAGNLNFSLTPTHAITLGWDGAQTRRSESRMEQDYVPATLQNPPAATQNDRYDGTITRGALFVQDDWDISAAWSLSAGLRWEKMRTAVISNALLSAPESSNEFSSIVSPLIQTLYKFSPDDQLRIGLTRTYKEPTMVELIPRLYTVDNNNSPTNPDTQGNPALRPELAWGLDAGVEHEIGKNGLIGASMFVRRIDDVIAEQLFQEGINWVLQPVNAGRANVHGITLEAKFTLNSLLEVAPPVELRANLTRNWSNVESLPGPNNRLDQQTPLSANLGLDYHLPGNEFTLGTNFNLTSGGPAQTTAQLASYSAPVRSLDAFALWAIDSQSRIRFSADNLLHQNQINAFNYADNGSSERTISTMRTATTLRLTWEVKFGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0X7</accession>
    <name>A0A2S9H0X7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glutathione S-transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1632</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93631">
        <property type="protein sequence ID" value="PRC93631"/>
        <property type="gene ID" value="S2091_1632"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034343">
        <property type="entry name" value="YibF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42673:SF12">
        <property type="entry name" value="PTHR42673:SF12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13417">
        <property type="entry name" value="GST_N_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="SSF47616"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GST N-terminal" evidence="1">
        <location>
            <begin position="1"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="2">
        <location>
            <begin position="83"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="202" mass="22414" checksum="3ABA9890E3603089" modified="2018-07-18" version="1">MKLIGSTASPFVRKVRIVLAEKKLECDLILENVWAPDTTIQSSNPIGKVPCLIMEDNSSMFDSHVIVEYLDTLTPVSKLIPSHGRERAGVKCWEALADGVLDAAILVRLELTQRAPELQSNDWIARQMSKVHAGLKAMSTGLGDAPFCGGVHYNLADVCVGCALGWLSFRFPELDWRTDYPNLAKLFDKLSERPSFKETIPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0Y9</accession>
    <name>A0A2S9H0Y9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative polysaccharide export protein, PEP-CTERM sytem-associated</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1913</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93526">
        <property type="protein sequence ID" value="PRC93526"/>
        <property type="gene ID" value="S2091_1913"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015159">
        <property type="term" value="F:polysaccharide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017477">
        <property type="entry name" value="PEP-CTERM_polysacc_export"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003715">
        <property type="entry name" value="Poly_export"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02563">
        <property type="entry name" value="Poly_export"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03027">
        <property type="entry name" value="pepcterm_export"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015758749" evidence="2">
        <location>
            <begin position="29"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="210" mass="22405" checksum="03B4584624649C19" modified="2018-07-18" version="1">MNTLRLNTLNWLACLSLAVCIICLGGCATNVNPPGSTDVQASNNDYLIGAGDTVNVIVWRNPEVSMVVPVRPDGKITTPLVEDIVANGKTPSQLARDIEKALAKFIQQPVVTVIVTMFSGPYAEQIRVIGQAAKPQALAYRQGMSLMDVLIAVGGMTDFAAGNKASIVRTVDGKQQKLSVRLNDLLKDGDISANMPVLPGDILVIPQSFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H102</accession>
    <name>A0A2S9H102_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1638</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93637">
        <property type="protein sequence ID" value="PRC93637"/>
        <property type="gene ID" value="S2091_1638"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="28"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="58"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="99"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="148"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="179"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="318" mass="37278" checksum="D4784B26E5B9731D" modified="2018-07-18" version="1">MFRIDRFSQVQQLAPVRTYLTFITHKKWIEVFGICILLLIFLRILVKIFPMLNPIDDLRFYFLGLLVSPKIFVEIYQGLLRSIKGAQENLPFLRVLVQFFPPALVSSFRFHYSLCYGFLCWLSRKKYEPDLPDGASIPFMNKSDYQTAFIMLLLMLLVEVPISSFAFGFSIKDPIERHWAHVLMITISIYTLILVLGDRWKLKNQHHQLDRNFLYLRCADRFFADIPVEQIKNIAIFKEELEKWKLAKRKLNFSFEIVSPCSLVDKPNLIIELVESSTLHVKRKSLKMSAPKYILLFVDEPSQTQSLIANSLTHHVEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H115</accession>
    <name>A0A2S9H115_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Gram-negative porin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_1659</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93658">
        <property type="protein sequence ID" value="PRC93658"/>
        <property type="gene ID" value="S2091_1659"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046930">
        <property type="term" value="C:pore complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015288">
        <property type="term" value="F:porin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006811">
        <property type="term" value="P:ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00342">
        <property type="entry name" value="gram_neg_porins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033900">
        <property type="entry name" value="Gram_neg_porin_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023614">
        <property type="entry name" value="Porin_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13609">
        <property type="entry name" value="Porin_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0406">Ion transport</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0626">Porin</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1134">Transmembrane beta strand</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015534791" evidence="4">
        <location>
            <begin position="22"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="domain" description="Porin_4" evidence="5">
        <location>
            <begin position="11"/>
            <end position="438"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF13609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC93658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="461" mass="47917" checksum="252EAFC4B74344E8" modified="2018-07-18" version="1">MNKKIIGLSIAMLFAANGAYAQSSNGSSVELYGVLDAAIGTVNHSLSGDANFPGTVNPISATKIPQTSATGVVTPGVNNSTSGMFNGGISDSRWGIRGSEDLGGGLKAIFTLESGFNLPTGNINNAAASLANNRNGTTGTVSAPSSLNGQLFNRQAFVGLSDAAWGTITLGRNYAPIYDMAVAYDPVQNAQLFSPLGFSGTYGGGGGVTENTRQDNSIKYKNTIGDFRIGAMYKVGGVAGESSAESGYAFFGGYSAAGFSIDAAYQAYTDALKETNSATANDINVTNYDTTSYFVAAKYAFGDATVRAGYESFTLKAPSNGLAALGATTINGYAIGNIPTAAANTADFNAANQTTDILFAGGDYNFTSAFNLAVGFYDIQSKSSSDFTGLSATGAPNKVNGFATQPSGNIYEYSLLADYHFTKRTDVYAGVLYSQYKGDAYSSLIYNTSNYIYAVGLRTKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H198</accession>
    <name>A0A2S9H198_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Pro-kumamolisin, activation domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">S2091_1738</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93737">
        <property type="protein sequence ID" value="PRC93737"/>
        <property type="gene ID" value="S2091_1738"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04056">
        <property type="entry name" value="Peptidases_S53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11377">
        <property type="entry name" value="Pro-peptidase_S53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015366">
        <property type="entry name" value="S53_propep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030400">
        <property type="entry name" value="Sedolisin_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09286">
        <property type="entry name" value="Pro-kuma_activ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00944">
        <property type="entry name" value="Pro-kuma_activ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="SSF52743"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51695">
        <property type="entry name" value="SEDOLISIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0106">Calcium</keyword>
    <keyword evidence="4 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 7" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0720">Serine protease</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015652731" evidence="9">
        <location>
            <begin position="37"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S53" evidence="10">
        <location>
            <begin position="235"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="397"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="7">
        <location>
            <position position="306"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="7">
        <location>
            <position position="310"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="7">
        <location>
            <position position="530"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC93737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="629" mass="64459" checksum="A129E46D9687D4D5" modified="2018-07-18" version="1">MNSKASAVKAGDLVLPRISTLAIALSLACGVMGAQAASDTSSWVGTKTEAFLPRVHTVDSTGAAVTADAIAVELAQGEKKSITVSLQLRNQDQLESFLTALHTPGNASYHKFLTPEQFAAQYSPTQAQVDAVVAHLSSAGFKNISVSSNRTLVSADGTVATVKQAFNTSLKSFNHQGRHVFANDKPAQVPAELGNIIGSVMGLQNAAIHHVMHSGVHDAAKKSSTAAASTGTEVAHIPTQYPGIYGDVTTPIASNATVGTIAEGSMTYTLQDFAAFLKANPTLPQGYVPTVVNVGTASGDESGEVEWALDSQVIYGTGVPKKLIFYVASSMEDAPLTATYNAAVTANVVSVVNVSLGECEADAKSSGSQAADDAVFKQAVAQGITFSIASGDAGPYNCDTDSQGNPGVAKTTTQKKTYDVSEPASSPYVVAVGGTALFTTSSGGYSGQAVWNEGTASTGDGSAVRIWSTGGGFSKDELAPSWQTASIVGSGHTYRGLPDLVFDAASASGTNIYINEAANGTAYGTVGGTSMASPIFVGIWARMESAHGNNLGFPNSAFYKAIPANAGLVFPVTSATVDGDSVDYNGWSTTYPGMKAAASGWSAATGFGSLNIDALNAYITANPTVFPPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1A0</accession>
    <name>A0A2S9H1A0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">1-acyl-sn-glycerol-3-phosphate acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1370</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93761">
        <property type="protein sequence ID" value="PRC93761"/>
        <property type="gene ID" value="S2091_1370"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002123">
        <property type="entry name" value="Plipid/glycerol_acylTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01553">
        <property type="entry name" value="Acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00563">
        <property type="entry name" value="PlsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="domain" description="PlsC" evidence="2">
        <location>
            <begin position="75"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="245" mass="27889" checksum="F95D491F81E57AB2" modified="2018-07-18" version="1">MHRFTLFLRSLVFTVLVALLTIVWAFVCMLVAPLPYNQRYWVTARWNVTVIWMGKVICGMRYQVIGEENLPDAPVILLSKHQSAWETIFYLMYMPRPLVFVFKKELHYIPFFGWGLALLRMIPIDRSKGKDAFAHVVIQGRKRLANGQWIIMFPEGTRIPVGQKGFYKGGGARLAVETNALVVPLAMNSGDCWPKNSFVKKPGLITVSIGKPISPEGKTSVELMQEVEAWVEAEMRVISPQNYQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1B2</accession>
    <name>A0A2S9H1B2_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">50S ribosomal protein L25</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">General stress protein CTC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rplY</name>
        <name evidence="6" type="synonym">ctc</name>
        <name evidence="8" type="ORF">S2091_1384</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93775">
        <property type="protein sequence ID" value="PRC93775"/>
        <property type="gene ID" value="S2091_1384"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008097">
        <property type="term" value="F:5S rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00495">
        <property type="entry name" value="Ribosomal_L25_TL5_CTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.120.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.240.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01336">
        <property type="entry name" value="Ribosomal_L25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01334">
        <property type="entry name" value="Ribosomal_L25_CTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020056">
        <property type="entry name" value="Rbsml_L25/Gln-tRNA_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029751">
        <property type="entry name" value="Ribosomal_L25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011035">
        <property type="entry name" value="Ribosomal_L25/Gln-tRNA_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020057">
        <property type="entry name" value="Ribosomal_L25_b-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037121">
        <property type="entry name" value="Ribosomal_L25_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001021">
        <property type="entry name" value="Ribosomal_L25_long"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020055">
        <property type="entry name" value="Ribosomal_L25_short"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01386">
        <property type="entry name" value="Ribosomal_L25p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14693">
        <property type="entry name" value="Ribosomal_TL5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50715">
        <property type="entry name" value="SSF50715"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00731">
        <property type="entry name" value="bL25_bact_ctc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 6 8" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 6" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_TL5_C" evidence="7">
        <location>
            <begin position="98"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF14693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC93775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="199" mass="21402" checksum="1CBF1264BC2DEF23" modified="2018-07-18" version="1">MKVIAFKRTLQGTGASRRLRKAGQTPGIVYGGTAAPVSITLDHNALYHALKKEVFHSSILDLEIDGTVEKVLLRDFQVHAYKQLVLHADFQRVDANHKIHVKVPLHFTNADVSPAVKLHAAVISHVMVELEISCLPGQLPEFIIADLANLDAGQSLHVKDIVLPEGVTAIIHGENQTVAIAVIPAGATAAEAEAVAEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1F0</accession>
    <name>A0A2S9H1F0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nuclease-related domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1420</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93811">
        <property type="protein sequence ID" value="PRC93811"/>
        <property type="gene ID" value="S2091_1420"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011528">
        <property type="entry name" value="NERD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08378">
        <property type="entry name" value="NERD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NERD" evidence="1">
        <location>
            <begin position="17"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="334" mass="38276" checksum="92EA5F2DED746410" modified="2018-07-18" version="1">MATLLPAIGSCLSRMTSGEKRFATLLEEKLEDDYLCWYDVSIGERTQHPDFIVFHPGRGLLVLEVKDWKLETIHSMDKQQATILTDRGLKHVLSPLEQARQYMFAVTNKLERDPQLVWPSGSLKGKPFFPYGHGVVLTNISRKQFDDAELGNVLPSHLVICKDEMTKSVECEEFQQRFWSMFPIKFKMQLSLPQIDRVRWHMFPEIRISAQQELFDEVDGQKVTEIPDILRVMDLQQEQLARSMGDGHRIIHGVAGSGKTLILGYRAEVLANVCQRPILILCYNKTLATKLASVMETKGLQDKVHVVNFHAWCSRQLDAYHVGKPPRNTDLNVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1R1</accession>
    <name>A0A2S9H1R1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Flagellar biosynthesis/type III secretory pathway protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1521</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93912">
        <property type="protein sequence ID" value="PRC93912"/>
        <property type="gene ID" value="S2091_1521"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018035">
        <property type="entry name" value="Flagellar_FliH/T3SS_HrpE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02108">
        <property type="entry name" value="FliH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0966">Cell projection</keyword>
    <keyword evidence="3" id="KW-0969">Cilium</keyword>
    <keyword evidence="3" id="KW-0282">Flagellum</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="FliH" evidence="2">
        <location>
            <begin position="100"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="238" mass="26284" checksum="6D31E6C82E9ED44D" modified="2018-07-18" version="1">MILRVPVIASEKRVLRGSFHKAYGVNSSLPNELSTGQQENAPQSLREAPDSAALIAQEEQLAERLREADETGKRAYEEGYEAGLRNGETDGREVYTSGLRQLEELTQNMNDTVQRSLDESEDMMVSIVFESVCKIIGDTLTTREGVVAVVEEALARIRGKSSVIIRVNPLDLELIEESAAFGVASEADWRADEGVAMGGCMIESEYGTLDARIDTQLNQLKRVLLSARHKPVDTQRDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1U1</accession>
    <name>A0A2S9H1U1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1115</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC93942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93942">
        <property type="protein sequence ID" value="PRC93942"/>
        <property type="gene ID" value="S2091_1115"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01743">
        <property type="entry name" value="GATase1_Anthranilate_Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006221">
        <property type="entry name" value="TrpG/PapA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00566">
        <property type="entry name" value="trpG_papA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GATase" evidence="1">
        <location>
            <begin position="4"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="191" mass="20790" checksum="312CC8E92B129C13" modified="2018-07-18" version="1">MLLMIDNYDSFTYNLVQYFGELGVEVRTYRNDEITLDEVAALAPTHICISPGPCTPHEAGISVGALQRFAGQIPMLGVCLGHQSIAAAFGGKVIRAKQVMHGKTSLIAHTGVGVFQDLPTPYTVTRYHSLAIERASLPNCLEVTAWTDDGEIMGVRHTDFNIQGVQFHPESILSEHGHALLKNFITVASAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1V2</accession>
    <name>A0A2S9H1V2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1539</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93930">
        <property type="protein sequence ID" value="PRC93930"/>
        <property type="gene ID" value="S2091_1539"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="125" mass="13587" checksum="8982DF2D8CB70FB9" modified="2018-07-18" version="1">MLNFQHVGHAVAGKIAHYRLGVRAPIACLIKSTSGAIPRTHHRTTVGGDPACHNIGTAIAIGIRQLVRRTCLPCAEYRIGTLGIDTTLRIRIPDARHCQTLRVLPNLHQIRAAIAIHISGEELLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H207</accession>
    <name>A0A2S9H207_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">UDP-N-acetylglucosamine 1-carboxyvinyltransferase</fullName>
            <ecNumber evidence="7">2.5.1.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Enoylpyruvate transferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">UDP-N-acetylglucosamine enolpyruvyl transferase</fullName>
            <shortName evidence="7">EPT</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">murA</name>
        <name evidence="9" type="ORF">S2091_1182</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>phosphoenolpyruvate + UDP-N-acetyl-alpha-D-glucosamine = phosphate + UDP-N-acetyl-3-O-(1-carboxyvinyl)-alpha-D-glucosamine</text>
            <dbReference type="Rhea" id="RHEA:18681"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:68483"/>
            <dbReference type="EC" id="2.5.1.7"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the EPSP synthase family. MurA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.7" evidence="7"/>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94009">
        <property type="protein sequence ID" value="PRC94009"/>
        <property type="gene ID" value="S2091_1182"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008760">
        <property type="term" value="F:UDP-N-acetylglucosamine 1-carboxyvinyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019277">
        <property type="term" value="P:UDP-N-acetylgalactosamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01555">
        <property type="entry name" value="UdpNAET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.65.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00111">
        <property type="entry name" value="MurA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001986">
        <property type="entry name" value="Enolpyruvate_Tfrase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036968">
        <property type="entry name" value="Enolpyruvate_Tfrase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013792">
        <property type="entry name" value="RNA3'P_cycl/enolpyr_Trfase_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005750">
        <property type="entry name" value="UDP_GlcNAc_COvinyl_MurA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00275">
        <property type="entry name" value="EPSP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55205">
        <property type="entry name" value="SSF55205"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01072">
        <property type="entry name" value="murA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1 7" id="KW-0132">Cell division</keyword>
    <keyword evidence="3 7" id="KW-0133">Cell shape</keyword>
    <keyword evidence="6 7" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 7" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="7" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="EPSP_synthase" evidence="8">
        <location>
            <begin position="7"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="region of interest" description="Phosphoenolpyruvate binding" evidence="7">
        <location>
            <begin position="22"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="UDP-N-acetylglucosamine binding" evidence="7">
        <location>
            <begin position="121"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="7">
        <location>
            <position position="116"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="92"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="304"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="326"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="2-(S-cysteinyl)pyruvic acid O-phosphothioketal" evidence="7">
        <location>
            <position position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC94009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="416" mass="44183" checksum="69C37D81B1F32AE3" modified="2018-07-18" version="1">MDKLLITGGTRLTGDVVISGAKNATLPILCAGLLTSDDLHLTNLPLLKDVSTMEKLLSQMGLRMNVSGNSVTLNGSNIHNLEAPYDMVKTMRASILALGPLLARFGEARVSLPGGCAIGARPVDQHIKGLQAMGAEITIEAGYIHAKAKKLKGTRIVTDMITVTGTENLLMAATLAEGETILENSACEPEVVDLANLLVAMGAQISGIGTSRMVIQGVSSLHGAQHHIISDRVEAATFLCAVAATGGDVTLQNTRVDILDVALDKLREAGAILITEADTIRIQMSSRPKAVSFRTTEYPGFPTDMQAQFMAMNCIAEGTSQVTETIFENRFMHVQELNRLGASIETEGHTAIVRGVDKLVGAPVMATDLRASASLVIAALAAEGETLIDRIYHLDRGYDQMEVKLSALGANIKRVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H271</accession>
    <name>A0A2S9H271_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Multidrug resistance efflux pump</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_1258</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94085">
        <property type="protein sequence ID" value="PRC94085"/>
        <property type="gene ID" value="S2091_1258"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043602">
        <property type="entry name" value="CusB_dom_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00529">
        <property type="entry name" value="CusB_dom_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="25"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="domain" description="CusB_dom_1" evidence="3">
        <location>
            <begin position="36"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="domain" description="HlyD_D23" evidence="4">
        <location>
            <begin position="61"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC94085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="393" mass="41753" checksum="CEF267838E5B4100" modified="2018-07-18" version="1">MTDKTTPQASQEIVATPSSTRRKRLLVVFGAIAVAASAFAAWRFFSDDSLRSTDNAYVGGQVVQVMPQIAGTVTRIMADNTDRIAAGASLIQLDSTDAQVELAAAEAKLAQAVRTVRGLYANDARYGADILAQQAELDKARADLAERKAVASIGAVTGEDLRHAANAVLKAEAIYTAAQQARAQALAQIDGSTFASHPDIQAAAQRVRAALIALSRSRIVAPVSGMVAQRVVQLGRRVGPGDRLMSIVPLDRLWVDANFKEVQLKGICPGQSAKVTADVYGKALIYHGRVEDIEAATGAAVALLPAQNATGNWIKIVQRVPVRISLDPAELLRNPLRIGMSTEVEINTSSCDAQWAAARKPKDDNAAGLYDVQAGIAETRVKEIIAENMGSHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H279</accession>
    <name>A0A2S9H279_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1257</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94084">
        <property type="protein sequence ID" value="PRC94084"/>
        <property type="gene ID" value="S2091_1257"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015562">
        <property type="term" value="F:efflux transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003423">
        <property type="entry name" value="OMP_efflux"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010131">
        <property type="entry name" value="RND_efflux_OM_lipoprot_NodT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02321">
        <property type="entry name" value="OEP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01845">
        <property type="entry name" value="outer_NodT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0564">Palmitate</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1134">Transmembrane beta strand</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU362097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="479" mass="51186" checksum="2998728D59961256" modified="2018-07-18" version="1">MKGQLATRAGAYVLTAELALILCGCATGNNISPTLKTPDIEHIAVGQRITQAAANNVGDTGSVTWWKFYQDPQLAHLLEIAMQEAPSIQTAAAHLHRAEAVLDLNKPSITGGAQIAGDRFPDHYTYPAPYAGSGGSDGSLTVNVRYHLDFWGKRREAQAAAGEQLKASQAEVADATLLLETAVMDAYIDLDLFYKTRDLAASALGNRLEIISMLAARQKAGLATDIDAIHANEAVTVTRGEIARLDSEITQRKSRIAALLGQDPGFAEQIERPSLVNISDPAPLSAIPSVLLGYRPDVALRRAEVDAAAHEIGVAKAAFYPDVDLTAFAGLMSLDVGYLLRAGSTALNAGPVLTLPIFDGGRLRSTLKGRTAEYDAAVANYRATLSTALQQVADGIALLESEQLRRNEAKTAEAHWRHVAELQDVRVRHGFSTAMDLLTAKTELLLRQRQLSEAEARIASAQIALIRALGGAWAPSSNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2G9</accession>
    <name>A0A2S9H2G9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glutathione S-transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1354</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94181">
        <property type="protein sequence ID" value="PRC94181"/>
        <property type="gene ID" value="S2091_1354"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00043">
        <property type="entry name" value="GST_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13409">
        <property type="entry name" value="GST_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="SSF47616"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GST N-terminal" evidence="1">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="2">
        <location>
            <begin position="87"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="203" mass="22158" checksum="1EA72F68C5840E0A" modified="2018-07-18" version="1">MKLYFAPGACSLSPHIVLREAGLEHTLEKVDLRSKQTATGVDFRTINPKGYVPTLQLNDGSILTEGPVIVQYLADLVPEKHLVPKAGSMERYRVMETLNYIGTELHKGFSPLFNPATSDAGKEVAINALLPRISLIAKQLGNSDYIAGSQFTVADAYLFVVLSWSAHVKLSLADWPTIQAYLARVAERPAVHAAMVAEGLIKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2H9</accession>
    <name>A0A2S9H2H9_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="9 10">tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase</fullName>
            <ecNumber evidence="9 10">2.8.4.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">(Dimethylallyl)adenosine tRNA methylthiotransferase MiaB</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">tRNA-i(6)A37 methylthiotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">miaB</name>
        <name evidence="14" type="ORF">S2091_0812</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 10">Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>[sulfur carrier]-SH + AH2 + N(6)-dimethylallyladenosine(37) in tRNA + 2 S-adenosyl-L-methionine = 2-methylsulfanyl-N(6)-dimethylallyladenosine(37) in tRNA + 5'-deoxyadenosine + [sulfur carrier]-H + A + 2 H(+) + L-methionine + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:37067"/>
            <dbReference type="Rhea" id="RHEA-COMP:10375"/>
            <dbReference type="Rhea" id="RHEA-COMP:10376"/>
            <dbReference type="Rhea" id="RHEA-COMP:14737"/>
            <dbReference type="Rhea" id="RHEA-COMP:14739"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:29917"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:64428"/>
            <dbReference type="ChEBI" id="CHEBI:74415"/>
            <dbReference type="ChEBI" id="CHEBI:74417"/>
            <dbReference type="EC" id="2.8.4.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="10">Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the methylthiotransferase family. MiaB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.8.4.3" evidence="9 10"/>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94191">
        <property type="protein sequence ID" value="PRC94191"/>
        <property type="gene ID" value="S2091_0812"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035596">
        <property type="term" value="F:methylthiotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01864">
        <property type="entry name" value="tRNA_metthiotr_MiaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005839">
        <property type="entry name" value="Methylthiotransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020612">
        <property type="entry name" value="Methylthiotransferase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013848">
        <property type="entry name" value="Methylthiotransferase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038135">
        <property type="entry name" value="Methylthiotransferase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006463">
        <property type="entry name" value="MiaB_methiolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023404">
        <property type="entry name" value="rSAM_horseshoe"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002792">
        <property type="entry name" value="TRAM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01938">
        <property type="entry name" value="TRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00919">
        <property type="entry name" value="UPF0004"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00273">
        <property type="entry name" value="(dimethylallyl)adenosine_tRNA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01061">
        <property type="entry name" value="methylthiotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00089">
        <property type="entry name" value="TIGR00089"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51449">
        <property type="entry name" value="MTTASE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01278">
        <property type="entry name" value="MTTASE_RADICAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50926">
        <property type="entry name" value="TRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 10" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="3 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 10" id="KW-0408">Iron</keyword>
    <keyword evidence="8 10" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="6 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 10 14" id="KW-0808">Transferase</keyword>
    <keyword evidence="10" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="MTTase N-terminal" evidence="12">
        <location>
            <begin position="3"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="Radical SAM core" evidence="13">
        <location>
            <begin position="143"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="domain" description="TRAM" evidence="11">
        <location>
            <begin position="378"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="12"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="49"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="83"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="157"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="161"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="164"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00033765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="PRC94191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="444" mass="49445" checksum="D4FD525378AF5A91" modified="2018-07-18" version="1">MQKKVFIKTFGCQMNQYDSDKMADVLNLSDGMIKTDNVEDADVVLLNTCSVREKAEEKVFSDLGRLRELKLKRPGLIIGVGGCVASQEGAAIVKRAPYVDVVFGPQTLHRLPQMLDQQRVSGKSQIDISFPEIEKFDHMPPAKVDGPTAFVSIMEGCSKYCSYCVVPYTRGEEVSRRFEDVLAEVAGLAAQGVKEISYLGQNVNAFRGVMADGEIADFALLLEYTAEIPGVERIRFITSHPKEFTQRLIDAYAKIPKIVDHLYLPAQHGSDRILSAMKRGYTVLEYKSVLRRLRAVRPNMSISSDFIVGFPGETDADFEAMMKLIDDIGFDNSFSFIYSPRPGTPAANLEDDTPHEVKLARLHRLQAVINDNVKRYSTEMIGSVQTVLVECPTVKDVNELQGRTENNRVVNFAGPAELIGQLVDVKITQSYNFSLRGELITEAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2J9</accession>
    <name>A0A2S9H2J9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putative threonine efflux protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_0836</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94215">
        <property type="protein sequence ID" value="PRC94215"/>
        <property type="gene ID" value="S2091_0836"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001123">
        <property type="entry name" value="LeuE-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30086">
        <property type="entry name" value="PTHR30086"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01810">
        <property type="entry name" value="LysE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006324">
        <property type="entry name" value="LeuE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="38"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="62"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="128"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="152"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="186"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC94215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="209" mass="22141" checksum="CA8AF5509EE9493A" modified="2018-07-18" version="1">MNGFFTYILIASLTIASPGPGIVLSISNSLKYGLKGAFPGIVGVAGGMFLVALASATSMGALLASSVTGFAIAKSIGAAYLIYLGIKLLRSSSIKLKGDSGEVPLHRPSTGARFKEGIILTVSNPKPIMFFIALFPQFINVASPYVTQFLFLSSTFCVLVFLIHSIYAMFAYAIKARIMSAGGFTIINRIGGTCFLLFAGLIFYTTKFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2T4</accession>
    <name>A0A2S9H2T4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Pyridoxal-phosphate dependent enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_0888</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cysteine synthase/cystathionine beta-synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94267">
        <property type="protein sequence ID" value="PRC94267"/>
        <property type="gene ID" value="S2091_0888"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016765">
        <property type="term" value="F:transferase activity, transferring alkyl or aryl (other than methyl) groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006535">
        <property type="term" value="P:cysteine biosynthetic process from serine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04608">
        <property type="entry name" value="CBS_pair_CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046353">
        <property type="entry name" value="CBS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001216">
        <property type="entry name" value="P-phosphate_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="PLP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="Trypto_synt_PLP_dependent"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="SSF53686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00901">
        <property type="entry name" value="CYS_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0129">CBS domain</keyword>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBS" evidence="6">
        <location>
            <begin position="337"/>
            <end position="401"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC94267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="458" mass="50248" checksum="EF1F5D2B4C320D89" modified="2018-07-18" version="1">MKNTTQPAVLEQIGNTPLIQVTRLDTGLCQLFLKLESQNPGGSIKDRIGLAMIEAAESDGRLKPGGTVVEATAGNTGLGLALVARAKGYRVVLVVPDKMSTEKVLHLKAMGAEVYLTRSDVGKGHPEYYQDYAARLAGEIPNSFFADQFNNPANPKAHETTTAPEIWEQTQHNVDAIVCGVGSSGTITGLTRFFRKHQPELEFVLADPQGSILAEYVETGHVSDTSGSWLVEGIGEDFIPPIADLSGVKKAYTISDQESFDTVRELLRAEGILAGSSTGTLLAAALRYCREQTEPKRVVTFVCDTGTRYLSKIYNDYWMIDRGLITRTTYGDLRDLISRRFDEGGVISVSKSDTLITTFNRMRNAEISQLPVIEAGKVVGVIDESDLLLKIADDAVRFHSTVDTTMTHKVETLTPDSSLEELRSILDRGLVAIIADQGHFYGLITRIDFLNYLRRKLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2W0</accession>
    <name>A0A2S9H2W0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0921</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94300">
        <property type="protein sequence ID" value="PRC94300"/>
        <property type="gene ID" value="S2091_0921"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="239" mass="26456" checksum="3F097345C8FF5F6E" modified="2018-07-18" version="1">MTMKKYNKPHVTAILIFSTVLCGCASKLPDRTLKPELIYTSGSPEPTQIILQQTQHVEVVSTIEGLRNSVASSDYKYSLTTAEGKTVALPFLDATNDSSGAGHIDFVFYNTASSNWIASSVVLSTHMEHVRGLFEWKSVDDLFVAVHVKTFTKDALVSKKTIEVCNISEAKNPVIQYDKLRPALRYCGKSGTTVYFPFTDTLTIENANNCCPGPAEQEHFGKRRSLNTFFEEAIITTSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H344</accession>
    <name>A0A2S9H344_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">2-hydroxychromene-2-carboxylate isomerase</fullName>
            <ecNumber evidence="1">5.99.1.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_1025</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>2-hydroxychromene-2-carboxylate = (3E)-4-(2-hydroxyphenyl)-2-oxobut-3-enoate</text>
            <dbReference type="Rhea" id="RHEA:27401"/>
            <dbReference type="ChEBI" id="CHEBI:59350"/>
            <dbReference type="ChEBI" id="CHEBI:59353"/>
            <dbReference type="EC" id="5.99.1.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the GST superfamily. NadH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.99.1.4" evidence="1"/>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94404">
        <property type="protein sequence ID" value="PRC94404"/>
        <property type="gene ID" value="S2091_1025"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018845">
        <property type="term" value="F:2-hydroxychromene-2-carboxylate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901170">
        <property type="term" value="P:naphthalene catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03022">
        <property type="entry name" value="DsbA_HCCA_Iso"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001853">
        <property type="entry name" value="DSBA-like_thioredoxin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014440">
        <property type="entry name" value="HCCAis_GSTk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044087">
        <property type="entry name" value="NahD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01323">
        <property type="entry name" value="DSBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006386">
        <property type="entry name" value="HCCAis_GSTk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DSBA" evidence="3">
        <location>
            <begin position="18"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="2">
        <location>
            <position position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR006386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR006386-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC94404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="217" mass="24803" checksum="4030695A3DC403CC" modified="2018-07-18" version="1">MNPETSMETATPYAPVALEFWYEFGSNYSYLSVMRVKELAEQYGVPIVWKPFLLGPIFKSFGWESSPFVLQKEKGAYVWQDMARECVKYNLPWKCPTSFPRSALLPMRVALLGADKPWIVDYNKRMMQVNFVEDLDIDNEEIVSKVLTELGLPASQLIAEAQSEDNKRRLRAQTETARQRGIFGAPTFFVDGTLFWGNDRLQDALIFAAGLKILPLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H370</accession>
    <name>A0A2S9H370_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SIR2-like domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1042</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94421">
        <property type="protein sequence ID" value="PRC94421"/>
        <property type="gene ID" value="S2091_1042"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039444">
        <property type="entry name" value="SIR2-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13289">
        <property type="entry name" value="SIR2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="SSF52467"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SIR2_2" evidence="1">
        <location>
            <begin position="137"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="353" mass="37793" checksum="39B5457C623806F8" modified="2018-07-18" version="1">MDTITASAQDALKKELQAIFSDGLVTIVGSGLSCAEGLPGMGALATELASKVPSAIPDADKSTWTAIEACLTSDGLEGALLKHAPTDNIESVVIKITAAFVLLKEQEVMTACMNGTRKLKIANLFPHISAANPKIAHIITTNYDRLIEFAAESEGWGVDSMMVGRYWGKHDPDLSDKLMVKSLSNGNKGTVRLLYRNHVKLFKPHGSLDWFMAGDTPMTCSMAFPSDPLIITPGAGKYKKGYGQPFDAHRERGNAAIDSASSILCIGYGFNDDHLQTHLSPKLKGGTKALLLTRDLSTTARAIVVQSSNCIALVSCADAASPGTIVVRGTTETLIPNMQWWDVENFVKGVLTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3B5</accession>
    <name>A0A2S9H3B5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="10">ABC-type antimicrobial peptide transport system permease component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">S2091_1093</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94472">
        <property type="protein sequence ID" value="PRC94472"/>
        <property type="gene ID" value="S2091_1093"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025857">
        <property type="entry name" value="MacB_PCD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12704">
        <property type="entry name" value="MacB_PCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="283"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="328"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="372"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="domain" description="MacB_PCD" evidence="9">
        <location>
            <begin position="22"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="8">
        <location>
            <begin position="313"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF12704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC94472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="409" mass="44163" checksum="6A6CF02705A8270D" modified="2018-07-18" version="1">MVSFLESIRSALLSIRAHALRSFLTALGIIIGVASVIAVVSIIQGFSATIGDQFKGLGSNSLTVYAYTPFELQLQGVVNRLSLNDYSQVLQHIEGVSNVSPSFMPFGNSGTTVKNSSTSTFTRVQAITTNYQDANQIYPELGRFITSDDNQSRRKVCVIGSKLRENLKLPNDPLGSYIEIGGEWFKVIGVTESRGEMFGISQDDYALIPFSVGQTIAGNAAKISVVITFTVDQMEQLDEIQDRVTALLRQLHRLKPGQANDFKVQTAQQLTDTFSKIIDTMTLVLGGIVSVSLLVGGIGIMNIMLVSVTERTREIGICKALGAQRHHILMQFLIEAVLLSILGGLIGLGLGYLLGIGAAKMIPNFPAASVPWWAVLLSFGFSSVVGIVFGIMPAAKAANLDPIEALRYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3F4</accession>
    <name>A0A2S9H3F4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="9">ABC-type sugar transport systems ATPase component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_0511</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94508">
        <property type="protein sequence ID" value="PRC94508"/>
        <property type="gene ID" value="S2091_0511"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008643">
        <property type="term" value="P:carbohydrate transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03301">
        <property type="entry name" value="ABC_MalK_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015855">
        <property type="entry name" value="ABC_transpr_MalK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008995">
        <property type="entry name" value="Mo/tungstate-bd_C_term_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040582">
        <property type="entry name" value="OB_MalK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17912">
        <property type="entry name" value="OB_MalK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50331">
        <property type="entry name" value="SSF50331"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="5" id="KW-1278">Translocase</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="8">
        <location>
            <begin position="4"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="37"/>
            <end position="44"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC94508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="370" mass="39865" checksum="6B3BDEEC685AD61C" modified="2018-07-18" version="1">MSQVKLTNIVKHFDDGTEVIHGINLDIRDGEFVVFVGPSGCGKSTLLRMIAGLESITGGELTIGGKLANDIAPAKRGLAMVFQSYALYPHMSVYENMAFGLKLAGMKAAEVETAVQQAAGILQIAHLLKRKPKDLSGGQRQRVAIGRAIVRKPEVFLFDEPLSNLDASLRVQMRLEISRLHQKLKTTMIYVTHDQVEAMTLGERIVVFNGGYIEQVGSPLELYDHPANLFVAGFLGAPKMNFLPAQVVSNSATEVVLKLSDGALVHAAAQGDALAVGEQVSLGIRAEHIVLKAAATAETNQVNVKVVLVENLGDSSIAYARIEGMEEMIAIKQSSETATLKSCDVGSLYLPANRCHVFDSSGRACKRILN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3G6</accession>
    <name>A0A2S9H3G6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1027</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94406">
        <property type="protein sequence ID" value="PRC94406"/>
        <property type="gene ID" value="S2091_1027"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="12"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="301" mass="32791" checksum="2A2C58BFC694F657" modified="2018-07-18" version="1">MPVSLLSLASMMEPLRGFVAVGRRMSITAAASDLCLTQSAMSRQVQALEERLGIKLLVRGHRSISFTAEGERLFRSADSALQQLQDTVGTIIPDHVCRPVTLSASIGVAGLWILPRLGHFQQLHPEIDVRVAANNRIQNLTSEGIDLAIRYGSRSDMEEGATLLFRETVAPVSHPSLALDQLTSVNDLAGQVLLEFDDPGRPWLHWNDWLASAGLGGVKPKGLLRFNQYDQVVQSAMAGQGVALGRVELIQPMLNDGRLRLVPTSHSGPRTDHSYWLIQANAAPRPEVAALTAWILSEASQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3H8</accession>
    <name>A0A2S9H3H8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Bacterial regulatory helix-turn-helix protein, lysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0523</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94520">
        <property type="protein sequence ID" value="PRC94520"/>
        <property type="gene ID" value="S2091_0523"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="312" mass="34352" checksum="5B8EAFCDCCB13E6C" modified="2018-07-18" version="1">MEINELRSFLVVARTANIRNAADELHQSPSALSKSIRRLEAALNTPLFDRVGKRLRLNLQGEQLRERAMQLVALADLTQAEFRGARQHLHCRIVGPALLQWRYGPTLSDLLQSSFPGSGVTFAAQFEDAAMAALTRGEADFALVTGVAVATTLPAGLEAIALGRMTMQLAAGLSHPLLQQATKQTTKHAANTATASWTVTTEQVLQHDFACPDRSLFCGVARGARSDGWRDDMLPRKIRFWLEDLQLLMTLVRSNQALAYLPDFAIQEPGLIRLKVVDCSYECVEECYLLWRPATASGWQNKVIAGLPSALN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3L6</accession>
    <name>A0A2S9H3L6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Mce related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0560</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94557">
        <property type="protein sequence ID" value="PRC94557"/>
        <property type="gene ID" value="S2091_0560"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003399">
        <property type="entry name" value="Mce/MlaD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02470">
        <property type="entry name" value="MlaD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="domain" description="MlaD" evidence="2">
        <location>
            <begin position="45"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="312" mass="33829" checksum="F8EF3D40BE557385" modified="2018-07-18" version="1">MENRSHALWAGFFTIAMLCAAIFAGIWLNRDKTQRIDYQIITSRAISGLNPQASVRYKGLAVGRVDNIDFDTKVAGQIIINISVDPDTPITQSTFATLGYQGVTGIAFVQLDDDGSNSVKLNVAAGTVPRIPLQPGLLEKLERSSSVILANAELVSARLAEFFTPENQKTMLGAFSNTAQATARWTKVADDLSPSLQLIPDLVHQTNQTLLSVQELSQNATQLSQQMTGVAKQLQDPDGPLNHTLSTLSDLSTNLQSETLPKITILTSETSNSMRTFNKTMEELKERPQILIFGKPTASAGPGEAGFVEPKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3Q3</accession>
    <name>A0A2S9H3Q3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative enzyme of the cupin superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94597">
        <property type="protein sequence ID" value="PRC94597"/>
        <property type="gene ID" value="S2091_0600"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008579">
        <property type="entry name" value="UGlyAH_Cupin_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05899">
        <property type="entry name" value="Cupin_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cupin_3" evidence="2">
        <location>
            <begin position="45"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="8"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="120" mass="13732" checksum="83516DEBA8437300" modified="2018-07-18" version="1">MSKIILFKEQTTQAEQDHPREERRQQGNPLRTTWNHFTNDTGEVFSGVWGSEVGSWRIEFGEREDEFFFVTEGRCRIIDEAGNTSEAGPGDALVIPAGFKGVFEVLEPMKKHYVIVERKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3W3</accession>
    <name>A0A2S9H3W3_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Aconitate hydratase</fullName>
            <ecNumber evidence="3">4.2.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">S2091_0675</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>citrate = D-threo-isocitrate</text>
            <dbReference type="Rhea" id="RHEA:10336"/>
            <dbReference type="ChEBI" id="CHEBI:15562"/>
            <dbReference type="ChEBI" id="CHEBI:16947"/>
            <dbReference type="EC" id="4.2.1.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the aconitase/IPM isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.3" evidence="3"/>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94672">
        <property type="protein sequence ID" value="PRC94672"/>
        <property type="gene ID" value="S2091_0675"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003994">
        <property type="term" value="F:aconitate hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047780">
        <property type="term" value="F:citrate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019679">
        <property type="term" value="P:propionate metabolic process, methylcitrate cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.19.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.499.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012708">
        <property type="entry name" value="2Me_IsoCit_deHydtase_FeS-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015931">
        <property type="entry name" value="Acnase/IPM_dHydase_lsu_aba_1/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001030">
        <property type="entry name" value="Acoase/IPM_deHydtase_lsu_aba"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015928">
        <property type="entry name" value="Aconitase/3IPM_dehydase_swvl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006249">
        <property type="entry name" value="Aconitase/IRP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036008">
        <property type="entry name" value="Aconitase_4Fe-4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000573">
        <property type="entry name" value="AconitaseA/IPMdHydase_ssu_swvl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11670">
        <property type="entry name" value="PTHR11670"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11670:SF43">
        <property type="entry name" value="PTHR11670:SF43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00330">
        <property type="entry name" value="Aconitase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00694">
        <property type="entry name" value="Aconitase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00415">
        <property type="entry name" value="ACONITASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53732">
        <property type="entry name" value="SSF53732"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02333">
        <property type="entry name" value="2met_isocit_dHY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aconitase" evidence="8">
        <location>
            <begin position="70"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="domain" description="Aconitase_C" evidence="9">
        <location>
            <begin position="657"/>
            <end position="787"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC94672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="864" mass="94137" checksum="54CE87D3FF62CF28" modified="2018-07-18" version="1">MNTANRKPLPGTKLDFFDTRAAVDAITPGAYDKLPYTSRVLAENLVRRCDPATLTDSLKQFIERRRDLDFPWFPARVVCHDILGQTALVDLAGLRDAIAAQGGDPALVNPVVPTQLVVDHSLAVECGGFDPDAFAKNRVIEDRRNEDRFDFINWTKKAFKNVDVIPPGNGILHQINLERMSPVVQVQDGVAFPDTLVGTDSHTPMVDALGVIAIGVGGLEAESVMLGRASWMRLPDIIGVELTGKPQPGITATDTVLALTEFLRKQKVVSSYLEFYGEGAANLTLGDRATIANMAPEFGATAAMFYIDEQTIKYLKLTGRDDELVKLVELYAKETGLWADSLKNAEYERVLKFDLSSVVRTIAGPSNPHNRVPTSELAARGISGVVENEAGLMPDGAVIIAAITSCTNTNNPRNMIAAGLIARNANARGLTRKPWVKSSLAPGSKTVTLYLEEAGLMPELEQLGFGVVAYACTSCNGMSGALDPVIQQEVVERDLYATAVLSGNRNFDGRIHPYAKQAFLASPPLVVAYAIAGTIRFDIEKDILGIDAAGHPVTLKDIWPSDEEIDAIVASSVKPEQFRKVYIPMFAKHADDGIKVSPLYDWRPQTTYIRRPPYWEGALAGVRSMTGMRPLAVLGDNITTDHLSPSNAIMLDSAAGEYLAKMGLPEEDFNSYATHRGDHLTAQRATFANPTLKNEMVLENGKVKAGSLARLEPEGKVTRMWEAIETYMERKQPLIIIAGADYGQGSSRDWAAKGVRLAGVEAIAAEGFERIHRTNLVGMGVLPLEFKPGVNRLTLGLDGTETYDVIGERTPRTTLTLVINRKNGERLEVPMICRLDTAEEVSIYEAGGVLQRFAQDFLESSKAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3W6</accession>
    <name>A0A2S9H3W6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Transcriptional regulator/sugar kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0654</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94651">
        <property type="protein sequence ID" value="PRC94651"/>
        <property type="gene ID" value="S2091_0654"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000600">
        <property type="entry name" value="ROK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18964">
        <property type="entry name" value="PTHR18964"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00480">
        <property type="entry name" value="ROK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="293" mass="30936" checksum="A86C661387B7E074" modified="2018-07-18" version="1">MNFNCGGAVQKVVVFDIGGSNSRIALFDGDDIVWRDQAATPGQQGPDAMVARMVELYLPTLNQRLLNLDVNIGVAITGQIVDGCVTAHNAAVLPGWQSYPLQKVLSEKLQRSVRIVNDARAAAWGEYLYGTGRGVDEFLFLTVSTGVGAGLVLNRRLHIARNGFDAEIGEMKTADGATLEEHASGTALGRLALEHGYAGAKSLCDAADLGDSRATELVENGIREIAKKLADLAVMLGIQRVAVGGSVGLRAGYIERLRSEVAKYPPIYQVELVAAALGHDAGLVGVAALARSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3Y9</accession>
    <name>A0A2S9H3Y9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_0589</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94586">
        <property type="protein sequence ID" value="PRC94586"/>
        <property type="gene ID" value="S2091_0589"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043231">
        <property type="term" value="C:intracellular membrane-bounded organelle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.5.90">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010693">
        <property type="entry name" value="Divergent_4Fe-4S_mono-cluster"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018967">
        <property type="entry name" value="FeS-contain_CDGSH-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042216">
        <property type="entry name" value="MitoNEET_CISD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06902">
        <property type="entry name" value="Fer4_19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09360">
        <property type="entry name" value="zf-CDGSH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00704">
        <property type="entry name" value="ZnF_CDGSH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ZnF_CDGSH" evidence="3">
        <location>
            <begin position="96"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="domain" description="ZnF_CDGSH" evidence="3">
        <location>
            <begin position="178"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC94586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="222" mass="24221" checksum="8179789F0DFACB68" modified="2018-07-18" version="1">MSIEIVQGREATIQFDAQRCVHSRNCVLSHPDVFVPNIQGEWIHPDAQPLEELIRLAQNCPSGAIRVMRNAQEETTSEVHLVEVAPLVNTVRVRENGPLALEAEFQIEGESQETPRATLCRCGLSKNKPYCDGAHQVAGFFATGEPVIVPYQGLAARNGLINIEPLPDGPLHIVGNLEIVSGTGRTCNTTIETYLCRCGHSANKPYCDGAHITAGFKTVEKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3Z0</accession>
    <name>A0A2S9H3Z0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0690</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94687">
        <property type="protein sequence ID" value="PRC94687"/>
        <property type="gene ID" value="S2091_0690"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="81"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="119"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="148"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="182" mass="20321" checksum="00E576E2B4FCB9BF" modified="2018-07-18" version="1">MSIISRNLLTVAFVVVAYTLSYMLNDWLFKQIEFTQGVAWVYLPAGLRLICTLLFAEAGVLGILFGSLLTSSMYALFPGDPITTIGYSLISALAPYFAYRYTLQEMRLERSLSNLTTTNLLICILLYGLCNPLLQLAWFIMRGVSSHYLPSLIVMSIGDLTGSLIVVYAFKTLLSFVPLPHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H458</accession>
    <name>A0A2S9H458_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Dehydrogenases with different specificities (Related to short-chain alcohol dehydrogenases)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0761</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94758">
        <property type="protein sequence ID" value="PRC94758"/>
        <property type="gene ID" value="S2091_0761"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="262" mass="27943" checksum="0004CB3CD313E163" modified="2018-07-18" version="1">MTTQNLSPTKAPVALITGAAVRIGRSIALTLAQRGWDIAVHFNNSEQPARELVAEITALGRRAIYLQCDLTDEAGVKKLVQRVVNGLGSIQCVVNNASAFEVDTAANFSHAMLDHHMHINLAAPVLLAQALFDATPDGQQTCVVNLLDQKLFNLNPDFLSYTLSKAALQCATTTLAQALAPKVRVVGVAPGTTLASIHQDQRNFEKTHQHAALGQSSTPQDIADAVHYLASARAVTGTILAVDGGQHLIPLARDVMYVVNTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H468</accession>
    <name>A0A2S9H468_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="9">ResB-like family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_0771</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94768">
        <property type="protein sequence ID" value="PRC94768"/>
        <property type="gene ID" value="S2091_0771"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017004">
        <property type="term" value="P:cytochrome complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023494">
        <property type="entry name" value="Cyt_c_bgen_Ccs1/CcsB/ResB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007816">
        <property type="entry name" value="ResB-like_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31566">
        <property type="entry name" value="PTHR31566"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05140">
        <property type="entry name" value="ResB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0201">Cytochrome c-type biogenesis</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="41"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="92"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="186"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="646"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="domain" description="ResB" evidence="8">
        <location>
            <begin position="39"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF05140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC94768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="715" mass="80087" checksum="6E7284C16C8423A0" modified="2018-07-18" version="1">MTTETPANTSSMTEPPSEQNQSRSKVNQFAEFVELISSMRFAISLLSLIAITSIIGTVLKQNEPMPNYVNQFGPFWFEVFRHLSLYSLYSSWWFLLIMTFLVLSTSLCLIRNTPKMLKDMRSWRDNVREQSLTNFAHKIAWNSALPRPALVAQVVKQLAQRGYKIKLVEKDNATLITAKQGAANKLGYIFAHSAIVIILIGGLLDSDLSIRFEQWFMGKVPFDGNGLISQIDGKHRLSLNNPTFRGNTMIPEGKTSDAAIIPQANGVFIQDLPFSIYLKKFIIEFYSTGMPKLFASEVEVQDHATGKTFPATIKVNEPLIYKGIAVYQSSFEDGGSKLRLAAYPMAGNHAESFEVKGEVGGTTPLATDDQYTIEWSGFRPFNVENMAANGQDLRAVDTKKSFNQQLATSLDQHSGSAAKGINTKDLKNVGASVQYKLRDKNGQAREFNNYMQSVKMDDSWVFLAGVRESPSEPFRYLRIPADDDDTVQDWMRLRAALLNPALRTKAAAEYANHALPNDAAGMKLRAQLQSSAEKSLAIFAGDGKVAGFMAVSQFLEKIPAEEQEKAANVFMKILNGSLWDLWQVARQQDGLPVVDINEKHAHFLQLASNALSDAFFYNAPVYLQLKSYDEVKASVLQVTRSPGKNIVYLGCVLLVLGIFSMFYIRERRVWVWIKDQQEGSEQSAHALLAMSSQRKTMDFEKEFVQLKTELLNSSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H497</accession>
    <name>A0A2S9H497_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Methyl-accepting chemotaxis protein (MCP) signaling domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">S2091_0802</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94799">
        <property type="protein sequence ID" value="PRC94799"/>
        <property type="gene ID" value="S2091_0802"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004888">
        <property type="term" value="F:transmembrane signaling receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004090">
        <property type="entry name" value="Chemotax_Me-accpt_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004089">
        <property type="entry name" value="MCPsignal_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033480">
        <property type="entry name" value="sCache_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00015">
        <property type="entry name" value="MCPsignal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17200">
        <property type="entry name" value="sCache_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00260">
        <property type="entry name" value="CHEMTRNSDUCR"/>
    </dbReference>
    <dbReference type="SMART" id="SM01049">
        <property type="entry name" value="Cache_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00283">
        <property type="entry name" value="MA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50111">
        <property type="entry name" value="CHEMOTAXIS_TRANSDUC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0807">Transducer</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="15"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="195"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="domain" description="Methyl-accepting transducer" evidence="9">
        <location>
            <begin position="274"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="247"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC94799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="519" mass="56552" checksum="80354EEAED9DA1D7" modified="2018-07-18" version="1">MHKLMDSFQIRTRLLLINALILIGVALITMVSLYSLRSSMIEERSAKIVSVIDSATSVLGHFNRLQQEGKLTEAQAKQQALEVLRTIRYEKTNYVFIYDVDGIKVLQPPAPETEGKPFKDVKDSHGKLFVQEMLDDAQNRGHGFVSYQFPKPGQAADFPKLSYVNYFADWKWTIGTGVYMDDVDKKFYSSARANVGMGIAMLIIISFITVMISRGILRQLGGEPNYAVEVVTQVAQGNLTIRANLHLTDKTSLLAQLQRMIEELRQLLLQVRNASESIDSAATEIAQGNLDLSGRTESQSASLEETASSMNQLTSTVRQNSESARQASDLAHTASKVAIHGGSVVKNVVVTMESIKNSSSKIVDIISVIDSIAFQTNILALNAAVEAARAGEQGRGFAVVASEVRALAHRSAAAAKEIKELIQHSVENIQSGATLVDDAGKAMDEIVNSVKSVTEIMTEIAQASKEQTQGIEQVNSAISEMEGVTQQNAALVEEAAAAAQSMRDQSRSLVDSVNTFRLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4D2</accession>
    <name>A0A2S9H4D2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Calcineurin-like phosphoesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0039</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94844">
        <property type="protein sequence ID" value="PRC94844"/>
        <property type="gene ID" value="S2091_0039"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003993">
        <property type="term" value="F:acid phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP_ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039331">
        <property type="entry name" value="PPA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22953">
        <property type="entry name" value="PTHR22953"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015431198" evidence="1">
        <location>
            <begin position="31"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="domain" description="Metallophos" evidence="2">
        <location>
            <begin position="64"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="315" mass="34898" checksum="C148F0E04D962DDA" modified="2018-07-18" version="1">MILLAHYLGTRMYKSLLPLALLASTLIAHANTAPTTPSTESRDATITVYAAGDIADCRTKKSTARSIATATLINAGIADDPQAIVLTMGDHTYPVGVQAEFETCYQPSWGKFKDRTYPSPGNHEYYSPNGIGYYQYFGEAAGSQRQSYYSVNKGAWHIISLNSNLNKEDLQTQLDWLAQDLKKNRSACTLAYWHHPVYSSGLHGNNKHMKPVWEMLMAAKADVILSGHDHHYERFALQNSQGDEDIQTGIREFIVGTGGAKLAPVFWKKSNSEIVNTNTNGVLKLLLKKQGYEWQFLPIEGSSFTDQGSTACHSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4F9</accession>
    <name>A0A2S9H4F9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Peptidase family S41</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0016</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94821">
        <property type="protein sequence ID" value="PRC94821"/>
        <property type="gene ID" value="S2091_0016"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005151">
        <property type="entry name" value="Tail-specific_protease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03572">
        <property type="entry name" value="Peptidase_S41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015672956" evidence="1">
        <location>
            <begin position="36"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="domain" description="TSPc" evidence="2">
        <location>
            <begin position="293"/>
            <end position="460"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="526" mass="58434" checksum="4279A028787B672D" modified="2018-07-18" version="1">MNSQHYLQRPNHFISRIACLLIASACYMVSASVSADTVANASLKTPPGSAEEWAVAAKIDLNAAYEETLNNHPGVYDPHNPDFINKLELAKKNGLAIASQVHDAAGYAAAISAFNTGLHDGHAGAFSTLDDKQMPVPRWPGFFSVWRGDGLYIYASEHADLHVGAKIVSCDGVQIKDVILNNVFAFEGRSDEVGHWWVRAGKVFVDRGNPFVTLPQQCQFSFDGQLFKRDIKWEATDSNFEQWRKRAYNGDELPVGLTEPRAKLFWVAMPTFDPNEAERIAYLKLSAEVLEKREHMLNADAIVIDLRHNQGGSSMWSKHFAEALWGEARVNRKMDAYSRDYQVWWRASQDNTDYMLGLVDQFKQQEILDSAAWASENGNAMKAALLRGDKYYIARDEAGKNIVTDPNVDLPTDPVPLSKPVYVIVPGQCASACLDALDVFTRFAGTKLIGAPSSADSTYMEVRVKTLPSGFADVLIPNKMYVNRPRVSGQGYLPEITVDDLEWSTANLLKVVEKDLALKYRDSTGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4L4</accession>
    <name>A0A2S9H4L4_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">UPF0434 protein S2091_0102</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0102</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0434 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94907">
        <property type="protein sequence ID" value="PRC94907"/>
        <property type="gene ID" value="S2091_0102"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01187">
        <property type="entry name" value="UPF0434"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005651">
        <property type="entry name" value="Trm112-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03966">
        <property type="entry name" value="Trm112p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="66" mass="7467" checksum="664ACE02B12C874F" modified="2018-07-18" version="1">MDSRLLDILVCPLCKGPLVYDKAAQELICKGDRLAYPVRDDIPVMWVDQARDFNSPKADMPNTQSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4P1</accession>
    <name>A0A2S9H4P1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Chalcone-flavanone isomerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0108</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94913">
        <property type="protein sequence ID" value="PRC94913"/>
        <property type="gene ID" value="S2091_0108"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016872">
        <property type="term" value="F:intramolecular lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016087">
        <property type="entry name" value="Chalcone_isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016088">
        <property type="entry name" value="Chalcone_isomerase_3-sand"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036298">
        <property type="entry name" value="Chalcone_isomerase_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16036">
        <property type="entry name" value="Chalcone_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54626">
        <property type="entry name" value="SSF54626"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015596989" evidence="1">
        <location>
            <begin position="23"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="domain" description="Chalcone_isomerase" evidence="2">
        <location>
            <begin position="24"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="196" mass="21496" checksum="7146A5065F363BE5" modified="2018-07-18" version="1">MKLPIKELLFCLAFALASTAQAIDIAGAKIDDTIQASNTKLKLNGAGIRYKVIFKVYVAALYLTETQNTVEGIISVPGPKQINLTMLRDVSSDTLGQAFMAGVQKNTEKAERAKLTTQFIQFGQLFSTVPELKKGDMIAMEWVPNVGTNMFINGRKVGETFPDMAFFNAILRIWLGENPVDSALKKQLLGGSSEHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4P9</accession>
    <name>A0A2S9H4P9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Branched-chain amino acid ABC-type transport system permease component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_0133</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94938">
        <property type="protein sequence ID" value="PRC94938"/>
        <property type="gene ID" value="S2091_0133"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001851">
        <property type="entry name" value="ABC_transp_permease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02653">
        <property type="entry name" value="BPD_transp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="65"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="98"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="135"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="196"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="230"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC94938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="296" mass="30492" checksum="F60BCF60D4DFBA0D" modified="2018-07-18" version="1">MDIFLQLVLSGVALGMIYAVIAFGYQLTFATSGTLNFGQGEALMLGALVGLSLVGTIHGGPYLSYVLMIPVVMVFGALQGMLVEWIGVRPAIKIKSEFGWIMSTIALAIIFKNVAENIWGKDDLTFPSPLSSAPITVLGANVQPMQIAVVIGALAIMAAVEVFNRKSIYGKAVVATANDRDAAALMGINTRMVITFSYALSSATAAFAGVLVAPLTLTGATMGASLGLKAFAVAIIGGLTSGVGAIVGGLILGIAETTTGYYISTGYKEVPGLLLLLLVLAIKPSGLFGKAAIKKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4W8</accession>
    <name>A0A2S9H4W8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glutathione S-transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_0225</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GST superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95030">
        <property type="protein sequence ID" value="PRC95030"/>
        <property type="gene ID" value="S2091_0225"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00043">
        <property type="entry name" value="GST_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02798">
        <property type="entry name" value="GST_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="SSF47616"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GST N-terminal" evidence="2">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="3">
        <location>
            <begin position="87"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC95030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="208" mass="23242" checksum="CCFAE3C8DA897CA9" modified="2018-07-18" version="1">MITVHHLNNSRSQRILWLLEELGLEYQIIHYQRDPITRLAPPELKAVHPLGKSPVISDGDLVVAESAAIIEYLVQSYGNGKLTPKPATPAYFRYLEWLHFAEGSAMLPFLLALYTSRLGDAAAALQPRISGEINNHLSHMNSALEGQAYLMGDEFTAADIQNSFVAEIAQARGLLEHYPHLASYTQRFQERPAYQRALKQGGEYKLGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5F1</accession>
    <name>A0A2S9H5F1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0409</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95214">
        <property type="protein sequence ID" value="PRC95214"/>
        <property type="gene ID" value="S2091_0409"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC95214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="32" mass="3358" checksum="A4CED8976A29D8C8" modified="2018-07-18" version="1">MVIGFLSGLLSGKNMKDGVLLRSLLGADILLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5I7</accession>
    <name>A0A2S9H5I7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0388</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95193">
        <property type="protein sequence ID" value="PRC95193"/>
        <property type="gene ID" value="S2091_0388"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC95193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="73" mass="8453" checksum="74C929FA2CC51B6D" modified="2018-07-18" version="1">MLNPKFNKPEIIANGKFQFQIVDTPKSVKTRTSISFAGYDPQFNRTLVELNIKTLNLYSEGHYSIYIKYVASY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSD1</accession>
    <name>A0A2S9GSD1_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_4687</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="PUGF01000045">
        <property type="protein sequence ID" value="PRC90598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90598">
        <property type="protein sequence ID" value="PRC90598"/>
        <property type="gene ID" value="S2091_4687"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013767">
        <property type="entry name" value="PAS_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00989">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PAS" evidence="5">
        <location>
            <begin position="13"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="5">
        <location>
            <begin position="286"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="4">
        <location>
            <begin position="414"/>
            <end position="633"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC90598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="645" mass="72220" checksum="DDDBF01D873EC5A3" modified="2018-07-18" version="1">MPTDSNPAPGKLNAGLLKKMIDHSREAVMVVDAATLTLLNVNLNACQMLGFLPEELLGNALSFVECSLLDLFFWEELAQEPLFEGTRIAETEWMRSDGTSFQIEKRIASYAEGDQHFWIIYAEDLTRRKAIEHQQLHLVSQLQSSLESTAEGILAVNLFGHVVNLNRRFALMWNLPEELLLERKENYMWEHIIASLSDGSGLTASLKKAHMEPHIESEDVLALRDGRYFICVSKPEFVRDSLIGRVFSVRDITTMKKIETDLLAARDIAEQASLDKSRMLDALIVSESRMRRLVNSNLIGIMQGDLKGKITEANEVLLRLFGVAREEFNRIGLNWLKLTTPENHKTYEHALNELRMHGQAPPFEVELISKTGAQLPAMVGLAQLEGSHTEWVGFVLDLTKQRESDRIKSDFISMVSHELRTPLTSIHGSLGLVESGVCGEIPLNAMNLVKIALKNSKRLGVLVNDLLDMEKLANGKMVLNSERFNLVALTRQAMEANLGYAQTFNVAFRFDEHPDHAWAMGDTNRLMQVFANLLSNAIKFSKDGDCVEIKVLEGAGVFRVEIKDRGPGIPVAFLDRIFKKFAQADDGDTRRQGGTGLGLNITQNLVEKMGGEIGFESEVGVGSVFWFTVVAGVQRRDDRVRDNEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSE2</accession>
    <name>A0A2S9GSE2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Peptidase M16 inactive domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_4667</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the peptidase M16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000042">
        <property type="protein sequence ID" value="PRC90631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90631">
        <property type="protein sequence ID" value="PRC90631"/>
        <property type="gene ID" value="S2091_4667"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011249">
        <property type="entry name" value="Metalloenz_LuxS/M16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011765">
        <property type="entry name" value="Pept_M16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001431">
        <property type="entry name" value="Pept_M16_Zn_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007863">
        <property type="entry name" value="Peptidase_M16_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00675">
        <property type="entry name" value="Peptidase_M16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05193">
        <property type="entry name" value="Peptidase_M16_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63411">
        <property type="entry name" value="SSF63411"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00143">
        <property type="entry name" value="INSULINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015500071" evidence="4">
        <location>
            <begin position="26"/>
            <end position="910"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M16" evidence="5">
        <location>
            <begin position="52"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M16_C" evidence="6">
        <location>
            <begin position="205"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M16_C" evidence="6">
        <location>
            <begin position="652"/>
            <end position="833"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF05193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC90631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="910" mass="101325" checksum="FB4F24242D2D825A" modified="2018-07-18" version="1">MPVQIKRVGFVVLMCFSLLQPSAWAGALPKDITQHASVEGITEYRLANGLKVLLMPDASKPTVTVNITYLVGSRQENYGETGMAHLLEHMMFKGTPKIPKIDIDFNQRGMHSNASTSLDRTNYFEQFEASDDNLHWAIKMEADRMIHSNIAKKDLDSEMTVVRNEFEMGENSPINVLIKRLQSIAFDWHNYGNSTIGNRSDIENVKIENLQAFYHLYYQPDNAVLLVAGKFDVNKTLTWISSEFGAIPKPKRSLPVFWTVEPTQDGERNFVVRRKGDTQIVMVAYKIPAALHPDNDALSFAGDILSDNPSGRLHKALVETGKAVDVFSTSIGSYAPGLQVIGAVVKKDDAIEPVRDALVAAIESFASTPPTPEEMERMKRNYRNQAEKTLTDPETIGLELSEVLALGDWRYFFQNRDQVEQVTSEQVAAAAARYFKRDNRIVGMFIPEDQPQRAEIPAAPSIQEVMQGFKPKLDLQTAEVFDPSPANIDKRTVHSNIGGLNVAMLTKKNKGETVSVALALHWGDEKSLFEKKMISSLTNAMLTRGNSKYSREQLNDEFSKLKITGDIYHFDTTRENLAAALALVAQVLKEPSFPENEFEQLKKQILSSLEGQRSEPNALAKQALDQHFNHYPKGDWRSSVTIAEAIERVNAITLDELKVFHKNFYGASKGELSLVGDIDVAATSKVIEQAFGNWTSLATYKRIDDAYTEIAPLKININTPDKENGLYLAKMNLNLNDQDEQYPALLVANYLFGGGAELNSRVMERIRQKDGLSYGGGSSLRVGSLDNASSFQLHAIAAPQNLAKVAVAMQEELNRVLKDGFSAEEVARAKSGLKQQAVQSRSQDASLVEDWNSYQYLQRSFAWTQAFEDKVNVLTAEQVNAAFKKMIDPSKLTVVIAGDESKMSSDKAAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSH4</accession>
    <name>A0A2S9GSH4_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">ATP synthase subunit beta</fullName>
            <ecNumber evidence="12">7.1.2.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">ATP synthase F1 sector subunit beta</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">F-ATPase subunit beta</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">atpD</name>
        <name evidence="14" type="ORF">S2091_4654</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>ATP + 4 H(+)(in) + H2O = ADP + 5 H(+)(out) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:57720"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="7.1.2.2"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Cell membrane</location>
            <topology evidence="12">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 12">Belongs to the ATPase alpha/beta chains family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.1.2.2" evidence="12"/>
    <dbReference type="EMBL" id="PUGF01000041">
        <property type="protein sequence ID" value="PRC90646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90646">
        <property type="protein sequence ID" value="PRC90646"/>
        <property type="gene ID" value="S2091_4654"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045261">
        <property type="term" value="C:proton-transporting ATP synthase complex, catalytic core F(1)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1140.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01347">
        <property type="entry name" value="ATP_synth_beta_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005722">
        <property type="entry name" value="ATP_synth_F1_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020003">
        <property type="entry name" value="ATPase_a/bsu_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004100">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036121">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000194">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_nucl-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024034">
        <property type="entry name" value="ATPase_F1/V1_b/a_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00006">
        <property type="entry name" value="ATP-synt_ab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02874">
        <property type="entry name" value="ATP-synt_ab_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50615">
        <property type="entry name" value="SSF50615"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01039">
        <property type="entry name" value="atpD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00152">
        <property type="entry name" value="ATPASE_ALPHA_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 12" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="6 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 12" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10 12" id="KW-0139">CF(1)</keyword>
    <keyword evidence="5 12" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="8 12" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 12" id="KW-1278">Translocase</keyword>
    <keyword evidence="2 12" id="KW-0813">Transport</keyword>
    <feature type="domain" description="AAA" evidence="13">
        <location>
            <begin position="140"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="148"/>
            <end position="155"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="PRC90646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="461" mass="49828" checksum="5E89D844699E9106" modified="2018-07-18" version="1">MADGKIVQCIGAVVDVEFPRNAMPKIYDALKMEGSELTLEVQQQLGDGIVRTIALGTSDGLRRGMIIQNTGKPIMVPTGTATLGRIMDVLGNPIDEAGPVVSDTHAAIHRKAPAYDELSPSQDLLETGIKVIDLVCPFAKGGKVGLFGGAGVGKTVNMMELINNIAKEHAGLSVFAGVGERTREGNDFYHEMKDSNVLDKVAMVYGQMNEPPGNRLRVALTGLTIAEGFRDEGKDVLFFVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGKLQERITSTKTGSITSIQAVYVPADDLTDPSPATTFAHLDSTVVLSRDIASLGIYPAVDPLDSTSRQLDPQVVGQEHYETARAVQGILQRYKELRDIIAILGMDELAPEDKLLVARARKMQRFLSQPFHVAEVFTGSPGKYVSLKDTIKGFKMIASGELDHLPEQAFYMVGTIDEAIEKAKKMAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GT37</accession>
    <name>A0A2S9GT37_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">P2 phage tail completion protein R (GpR)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4454</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000034">
        <property type="protein sequence ID" value="PRC90873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90873">
        <property type="protein sequence ID" value="PRC90873"/>
        <property type="gene ID" value="S2091_4454"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009678">
        <property type="entry name" value="Phage_tail_completion_R"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06891">
        <property type="entry name" value="P2_Phage_GpR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC90873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="159" mass="17810" checksum="D6C6F017B7DFB9D6" modified="2018-07-18" version="1">MYKPPNLRQHLTNAIPDLKQNPDKLLIFADQGHTVASGTGSLSFEYQYRLNIIITDFSGDPDAIMVPLLAWITVHQIELLANPDLRKKGIGFEVDFNNHETIDISIALNLTERTIVKQQDGGKLQITHPPEPQTTPAFDDAFWTLYAGDSLLAEWVTPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GT68</accession>
    <name>A0A2S9GT68_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">16S rRNA uridine pseudouridylate synthase and related pseudouridylate synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4396</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000033">
        <property type="protein sequence ID" value="PRC90903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90903">
        <property type="protein sequence ID" value="PRC90903"/>
        <property type="gene ID" value="S2091_4396"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140098">
        <property type="term" value="F:catalytic activity, acting on RNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009982">
        <property type="term" value="F:pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034470">
        <property type="term" value="P:ncRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001522">
        <property type="term" value="P:pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01479">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S4" evidence="1">
        <location>
            <begin position="6"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="237" mass="26323" checksum="5A68C0DFA0E99CB0" modified="2018-07-18" version="1">MSNSIRLAKRLAEQIPCSRQAAEQYIAGGWVTVDGLVIEEPGFRVLEQQLVELMPKASLATLADVTILWHKPAGVVTETLVQQLSLETMAAGDRSGHRFLKRHTTNLTLTNALETEASGLVVFSQDWNVNRKLVDDASKLEQEFLVEVSGDIANGGLALLNHGLSFNGRALAPIKVSWQNETRLRFAVKGVQMHQITHMCQQVGLTVVSLKRLRIGRIPLSSLPVGQWRYLLGYERF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTL1</accession>
    <name>A0A2S9GTL1_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Glucose-6-phosphate 1-dehydrogenase</fullName>
            <shortName evidence="5">G6PD</shortName>
            <ecNumber evidence="5">1.1.1.49</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">zwf</name>
        <name evidence="9" type="ORF">S2091_4238</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>D-glucose 6-phosphate + NADP(+) = 6-phospho-D-glucono-1,5-lactone + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:15841"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:57955"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:61548"/>
            <dbReference type="EC" id="1.1.1.49"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5">Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 1/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the glucose-6-phosphate dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.49" evidence="5"/>
    <dbReference type="EMBL" id="PUGF01000030">
        <property type="protein sequence ID" value="PRC91050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91050">
        <property type="protein sequence ID" value="PRC91050"/>
        <property type="gene ID" value="S2091_4238"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00115">
        <property type="reaction ID" value="UER00408"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004345">
        <property type="term" value="F:glucose-6-phosphate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006006">
        <property type="term" value="P:glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006098">
        <property type="term" value="P:pentose-phosphate shunt"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00966">
        <property type="entry name" value="G6PD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001282">
        <property type="entry name" value="G6P_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019796">
        <property type="entry name" value="G6P_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022675">
        <property type="entry name" value="G6P_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022674">
        <property type="entry name" value="G6P_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23429">
        <property type="entry name" value="PTHR23429"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02781">
        <property type="entry name" value="G6PD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00479">
        <property type="entry name" value="G6PD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000110">
        <property type="entry name" value="G6PD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00079">
        <property type="entry name" value="G6PDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00871">
        <property type="entry name" value="zwf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00069">
        <property type="entry name" value="G6P_DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="1 5" id="KW-0313">Glucose metabolism</keyword>
    <keyword evidence="2 5" id="KW-0521">NADP</keyword>
    <keyword evidence="3 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="G6PD_N" evidence="7">
        <location>
            <begin position="15"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="domain" description="G6PD_C" evidence="8">
        <location>
            <begin position="186"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="236"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="50"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="144"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="174"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 6">
        <location>
            <position position="178"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="212"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="231"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="322"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022526"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC91050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="465" mass="51347" checksum="D56D2800F0017E3D" modified="2018-07-18" version="1">MSKTNTGKGHADALVIFGVTGDLARKMIFPALYAMVKRGVLTVPVIGVASSPWTISKLHKQVIDSLKQAGKIDDQPALNRLLELLSYVSGDYNDPNTFQALKQILGKSRRPAHYLAIPPALFSTVIKGLAASGLAHGARVIVEKPFGRDLASARELNRIALSAFPEAAIFRIDHYLGKEAIMNILYFRFANSFLEPIWNRNYVKSVQITLGESFGVKGRGAFYESAGCLRDVVQNHLFQIVALLAMEPPAFQGFGAVQNEKAKVFQAMRPLRPDDIVRGQYSGYKKEAGVAKNSKVETFCAARLHIDSWRWQGVPWYLRAGKYLATTAAEVVIELKPPPQMLFDDAISAHGRSNYLRFRLSPNSAIALAARVKRPGKEFVGEQQELFLLDEQHGAETPYERLLSDAMTGDAALFTREDAVEAAWSVVEGVLDTHSPLHTYQPGSWGPKQANTLIAADGHWYDPIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTN9</accession>
    <name>A0A2S9GTN9_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">Ribonuclease H</fullName>
            <shortName evidence="5">RNase H</shortName>
            <ecNumber evidence="4 5">3.1.26.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rnhA</name>
        <name evidence="7" type="ORF">S2091_4180</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>Endonucleolytic cleavage to 5'-phosphomonoester.</text>
            <dbReference type="EC" id="3.1.26.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="5">Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 5">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the RNase H family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.26.4" evidence="4 5"/>
    <dbReference type="EMBL" id="PUGF01000029">
        <property type="protein sequence ID" value="PRC91084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91084">
        <property type="protein sequence ID" value="PRC91084"/>
        <property type="gene ID" value="S2091_4180"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004523">
        <property type="term" value="F:RNA-DNA hybrid ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006401">
        <property type="term" value="P:RNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd09278">
        <property type="entry name" value="RNase_HI_prokaryote_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00042">
        <property type="entry name" value="RNase_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002156">
        <property type="entry name" value="RNaseH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022892">
        <property type="entry name" value="RNaseHI"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00075">
        <property type="entry name" value="RNase_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50879">
        <property type="entry name" value="RNASE_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0540">Nuclease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNase H type-1" evidence="6">
        <location>
            <begin position="1"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="9"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="47"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="69"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="133"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC91084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="144" mass="15746" checksum="DBBA7A114680C393" modified="2018-07-18" version="1">MDQINIYTDGACKGNPGPGGWGALLVVGANEKELFGGEANTTNNRMELMAVIQALSALKRPCHVTIHTDSQYVLKGITEWIEGWKAKGWKTASKAPVKNVDLWQTLDAATTQHQIEWRWVKGHSGHAGNERADQLANRGVEAVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTW5</accession>
    <name>A0A2S9GTW5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="8">MMPL family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_4151</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000028">
        <property type="protein sequence ID" value="PRC91150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91150">
        <property type="protein sequence ID" value="PRC91150"/>
        <property type="gene ID" value="S2091_4151"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004869">
        <property type="entry name" value="MMPL_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03176">
        <property type="entry name" value="MMPL"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="45"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="261"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="286"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="317"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="359"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="392"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="446"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="649"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="674"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="701"/>
            <end position="722"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="742"/>
            <end position="763"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="775"/>
            <end position="799"/>
        </location>
    </feature>
    <feature type="domain" description="MMPL" evidence="7">
        <location>
            <begin position="194"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="domain" description="MMPL" evidence="7">
        <location>
            <begin position="499"/>
            <end position="798"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC91150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="812" mass="89194" checksum="37F421E37635F3CD" modified="2018-07-18" version="1">MTINLTLLEVVNGENKTLTQTQAQIKPQPQLHPKLGLVERFIEPILFNFRLPVLIFFLLASILFAYEAAQLRPDASFQKMVPIFHPYIANYLKYENELRPLGNVVRIAVENKNGDIYSKEYLDTLKKITDEVFYVPGVDRGNLKSLWTPNVNWMEVTEAGMTGGQIIPQGFDGTPEKIEQVRTNIVRSGRIGSLVAADGHSTIVLVPLLETDPDTGAKLNYGQFSERLETLIRQKYETKDIKIHITGFAKVVGDLIHGAKAIGVFFAIAFVLTILLLLAYSRCWRSTSVTILCCSLAVIWQLGIVRMLGFGLDPYSILVPFLTFAIGVSHAVQNINTMAAARLTGSSNVDTAKLTFRQLFIPGSVALLCDAVGFSTLLVIKIGVIQELAISASIGVAVIILTKMFLLPILMSYVGVSDACLRHQAKKQGSQHRAAHFLSRFAEPRFAWVAVLGAALLLGVAWNISRDLKIGDLDAGAPELRPDSQYNRDNAYISAHYSTSPDVFVVMVKTPANECGSYPVAEVVDRFQWEMEQVAGVESTTSLFSGMKKVIAATNGGDLRWQALSRNRFVSNAAHRMLPSELYSNDCSMLPVLIFLTDHKADTLTRIAKAAENFAAANNDATVQFLLAAGNSGIEAATNKVIKQAEPQMLMLVYGIVALLVLWEFRSWRVTLCIMLPLYITSVLCEAIMAKLGLGVKVATLPVIALGIGIGVDYGIYIYNRIQHFLDQGLLLKAAYFETLKSTGAAVALTGVTLSLGVLTWVWSDIKFQADMGLLLTFMFLWNMVGAIVMIPALAALLVPQRPGLISLKRIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTX5</accession>
    <name>A0A2S9GTX5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4161</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000028">
        <property type="protein sequence ID" value="PRC91160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91160">
        <property type="protein sequence ID" value="PRC91160"/>
        <property type="gene ID" value="S2091_4161"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="91"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="130"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="165"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="205" mass="22772" checksum="2B620542DFF7745D" modified="2018-07-18" version="1">MAIRDLHRISALMIAAYAALHVTNHIVGIGGAVSHINFMEAIRPIYRQPVIEAVLLFCVMFQVGSGLFLAIRGWKQRHGLIPWVQAASGMYLAFFLVVHVSAVLLGRAVLKLDTNFYFAAAGFYETPYKFFFAPYYFFAIFALFTHLGCAAYWQVQARPTLVRALTVLIPAGCGLVISLFIVLSLAGVLHPVEIPAEYKATYELK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GU93</accession>
    <name>A0A2S9GU93_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD</fullName>
            <ecNumber evidence="6">2.1.1.190</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">23S rRNA(m5U1939)-methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rlmD</name>
        <name evidence="9" type="ORF">S2091_4065</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>S-adenosyl-L-methionine + uridine(1939) in 23S rRNA = 5-methyluridine(1939) in 23S rRNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42908"/>
            <dbReference type="Rhea" id="RHEA-COMP:10278"/>
            <dbReference type="Rhea" id="RHEA-COMP:10279"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74447"/>
            <dbReference type="EC" id="2.1.1.190"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.190" evidence="6"/>
    <dbReference type="EMBL" id="PUGF01000026">
        <property type="protein sequence ID" value="PRC91280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91280">
        <property type="protein sequence ID" value="PRC91280"/>
        <property type="gene ID" value="S2091_4065"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070041">
        <property type="term" value="F:rRNA (uridine-C5-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01010">
        <property type="entry name" value="23SrRNA_methyltr_RlmD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001566">
        <property type="entry name" value="23S_rRNA_MeTrfase_RlmD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030391">
        <property type="entry name" value="MeTrfase_TrmA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002792">
        <property type="entry name" value="TRAM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010280">
        <property type="entry name" value="U5_MeTrfase_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11061">
        <property type="entry name" value="PTHR11061"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05958">
        <property type="entry name" value="tRNA_U5-meth_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51687">
        <property type="entry name" value="SAM_MT_RNA_M5U"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50926">
        <property type="entry name" value="TRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01231">
        <property type="entry name" value="TRMA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 6 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="5 6 7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 6 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TRAM" evidence="8">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="6 7">
        <location>
            <position position="402"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="74"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="80"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="83"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="162"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="270"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="299"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="304"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="320"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="348"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="369"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC91280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="445" mass="49746" checksum="7ED0512D882DE01A" modified="2018-07-18" version="1">MSDTKMKITALDMDARGIGHLQNEDGTDGKVVFVDGALPGEVVSVQTYRKKAHWENALMTELHQESSQRVKPKCSYFGLCGGCSMQHLTADAQVAIKQRVLEDSLWHISKVKADTMLRPIYGPTWGYRYRARLSVRNVLKKGIVLVGFHEKKSRYVANTETCEILPPHVSAMLMPLRELIAQLSIVNDLPQIELAVGEDVTAMVLRIMKPMSAADEVLLKAFADKYKVQWWLQTKGLETVEIYYPVTPQLHYLLPEFGVKMPFKPTDFTQVNHHINRVMVVRALRLLDVQPHERIADLFCGLGNFTLPLATQAREVVGIEGSTVLTERALENAVANGLSDKTSFSTRNLFEITAEDLLVLGKFDRYLVDPPRDGAMALCEALIQLAKIDPEFMPRRIVYVSCSPGTLARDAGLLVKAGYVTSYAGVVNMFPHTSHVESMAVFDLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUA9</accession>
    <name>A0A2S9GUA9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">GGDEF: diguanylate cyclase (GGDEF) domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_3970</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000025">
        <property type="protein sequence ID" value="PRC91299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91299">
        <property type="protein sequence ID" value="PRC91299"/>
        <property type="gene ID" value="S2091_3970"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01948">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001633">
        <property type="entry name" value="EAL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035919">
        <property type="entry name" value="EAL_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013656">
        <property type="entry name" value="PAS_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00563">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08448">
        <property type="entry name" value="PAS_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00052">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141868">
        <property type="entry name" value="SSF141868"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50883">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="46"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="72"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="104"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="144"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="3">
        <location>
            <begin position="383"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="2">
        <location>
            <begin position="429"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="2">
        <location>
            <begin position="545"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="3">
        <location>
            <begin position="618"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="5">
        <location>
            <begin position="702"/>
            <end position="840"/>
        </location>
    </feature>
    <feature type="domain" description="EAL" evidence="4">
        <location>
            <begin position="849"/>
            <end position="1103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC91299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="1106" mass="123730" checksum="4B6230C9BE95CE81" modified="2018-07-18" version="1">MQLPDHRFSTHRLTLFALYAGALLSFAALLPELISYATNTTPQDSNYTTFALGSITLLLFAMAYLYRSGHNFAINIAIIAMALSIPFVFDPHAFLYSSVPQGIWLPFIFALAVSQFRVALITLAISFTCAFVSYPSAFRSPRAIVESVIIFLLLMIGKLVVHRLMKAAIDAQNQINASKIEVNDNENTANFILDCILNGFEYGQLVYENGEPVDFIYIKVNETFETLTGLKNVIGKKLSEVMPGNTKNNDERLAVYGRVAATGMPVRVETYFPQLEKWMQLSVSSPKAEHFVAIYDVIAEPSMMGKKVTISTEQQQAFIQDAPVSIAMVDLDMNYIAYSQKWLKENGRGYKDLTGRNHYEINPDMPPEWKKLHQQAFAGVAINNVEFMWQQNDGTQRWLYCSAQPWKYESGEIGGLIIFREDITGRKIAESDLRSVLEESGDAIWISNSKGNFIYANPTAARLTGHSEIELSQLRLTDMIHEEREDELLEYLALTQNAKFTRREWLINHKNGSTVSVELTTGHLPGGRMIAFGRDLTEKMKTETERFKLFQAVEQSPGCIMITNLNADIEYVNAAFLKRTGYSRKEIIGKNPRLIKSGKTPPQTFVELWKTIKQGETWQGEIANVSKNGQEFIQFTTISPIRQSNGSICNYIAISEDITGRKKGEERIFELAYFDQLTGLPNRTLLLDRLNQVIAISYRSGVYGALLFIDLDHFKNINDTLGHQKGDLVLKQVAECLMQRIREGDTVARFGGDEFVVLLAGLGTDDDIAANKAKTAALKLLDALNQTYQLGDVVHHSTASIGVAMFNGQLSTTDELLKQADLAMYKSKKAGRNTIRFFDPSLESAMKQQATLEEDLRIALQDKQFILHYQGQFTSESKLTGAEVLVRWKHPEQGMMSPALFIPFAEESGLILPIGNWVLETACNQLAAWGKLPNMRKLVLAVNVSALQFRQPDFIETVLAIIERSGANPHRLKLELTESMLVENVDDIIQKMLTLKAHGLGFSLDDFGTGYSSLSFLKRLPLDQLKIDQSFIRDVHSDPNGAAIAKTIVSLGKSLGLNVIAEGVETSEQREFLANAGCFAYQGYLFSRPLAIQDFEELAMGALIEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUD0</accession>
    <name>A0A2S9GUD0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3985</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000025">
        <property type="protein sequence ID" value="PRC91314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91314">
        <property type="protein sequence ID" value="PRC91314"/>
        <property type="gene ID" value="S2091_3985"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="86" mass="9939" checksum="386664656C94E6BB" modified="2018-07-18" version="1">MKIIRFQRSFQSCSRSSPLLIEALSSLPIRYNARYPVRQHHAALLITTFLSPFGLKIAAIQASRHNFIEKDSYVKLPPRISRRQPC</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUJ9</accession>
    <name>A0A2S9GUJ9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3926</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000024">
        <property type="protein sequence ID" value="PRC91381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91381">
        <property type="protein sequence ID" value="PRC91381"/>
        <property type="gene ID" value="S2091_3926"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="98" mass="10820" checksum="742FF91FE8B149FF" modified="2018-07-18" version="1">MRWLVWLVLGLLVYLAVRSRAKTLQENFRNSARAEFDAQAGASAQPAAKPSSPIENMVACSYCQLYLPASEAISANDHYFCCEEHAQYYSNASSKPAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUK3</accession>
    <name>A0A2S9GUK3_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">GTPase Obg</fullName>
            <ecNumber evidence="5">3.6.5.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">GTP-binding protein Obg</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">obg</name>
        <name evidence="8" type="ORF">S2091_3935</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="5">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.-" evidence="5"/>
    <dbReference type="EMBL" id="PUGF01000024">
        <property type="protein sequence ID" value="PRC91390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91390">
        <property type="protein sequence ID" value="PRC91390"/>
        <property type="gene ID" value="S2091_3935"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01898">
        <property type="entry name" value="Obg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.210.12">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01454">
        <property type="entry name" value="GTPase_Obg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031167">
        <property type="entry name" value="G_OBG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014100">
        <property type="entry name" value="GTP-bd_Obg/CgtA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006074">
        <property type="entry name" value="GTP1-OBG_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006169">
        <property type="entry name" value="GTP1_OBG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036726">
        <property type="entry name" value="GTP1_OBG_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045086">
        <property type="entry name" value="OBG_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11702">
        <property type="entry name" value="PTHR11702"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01018">
        <property type="entry name" value="GTP1_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002401">
        <property type="entry name" value="GTP_bd_Obg/CgtA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82051">
        <property type="entry name" value="SSF82051"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02729">
        <property type="entry name" value="Obg_CgtA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51710">
        <property type="entry name" value="G_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00905">
        <property type="entry name" value="GTP1_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51883">
        <property type="entry name" value="OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Obg" evidence="7">
        <location>
            <begin position="1"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="domain" description="OBG-type G" evidence="6">
        <location>
            <begin position="160"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="166"/>
            <end position="173"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="173"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="191"/>
            <end position="195"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="193"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="213"/>
            <end position="216"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="283"/>
            <end position="286"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="314"/>
            <end position="316"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC91390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="368" mass="40745" checksum="9A6B32817874C49B" modified="2018-07-18" version="1">MKFIDEARIEIVGGDGGNGIASFCREKFRPFGGPDGGDGGKGGSIFAVADRNINTLVDFRFSKLHMAKRGENGRGADCYGKGADDVFLRMPVGTLIFDRNTEELIADLTEHGQEVLLAKGGDGGWGNIHFKTSTNRAPRQHGNGKEGERRELRLELKVLADVGLLGMPNAGKSTFITAVSNARPKIADYPFTTLHPNLGVVRVSHEKSFVIADIPGLIEGAAEGAGLGHQFLRHLQRTGLLLHIIDFSPFDDVDPVKEAKALAQELRKYDESLFDKPRWLVLNKLDMVPEDERKKRVKDFVKKLNWKGPVFEISALNREGCEDLVMAIYSHLAEKRTQEIRAEETTMEEAAHGILSIEPDDPRFKIMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUM8</accession>
    <name>A0A2S9GUM8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="10">TonB dependent receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">S2091_3901</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000024">
        <property type="protein sequence ID" value="PRC91356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91356">
        <property type="protein sequence ID" value="PRC91356"/>
        <property type="gene ID" value="S2091_3901"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039426">
        <property type="entry name" value="BtuB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30069">
        <property type="entry name" value="PTHR30069"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="3 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 10" id="KW-0675">Receptor</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="2 6" id="KW-0798">TonB box</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015680599" evidence="7">
        <location>
            <begin position="22"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="domain" description="Plug" evidence="9">
        <location>
            <begin position="46"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="8">
        <location>
            <begin position="184"/>
            <end position="713"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC91356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="737" mass="80504" checksum="2DBCC052E4362548" modified="2018-07-18" version="1">MKFPLKPFVIFLAAAPFSAIAQEVVLDAIVVTGQKIDVQSFSGTDVDAASLASQRPVSSDTASLLQDVPGISLYGAGGISSLPAIHGMADDRVRIQVDGMGLVSACPNHMNSPLSYIDPTNVDIIKVYTGITPVSAGGDSIGGTIQVNSAAPEFARSGEGTLLKGQLGAFYRSNGDGYGTNLSTTLANEYLNLTYNGSTAQSNNYRAAQDFKAAGPAAADRGWLAGNEVGSSAYKSENHELGLALRHENNLLEFKASMQDVPYELFPNQRMDMTENNNKQFSLRYTGQFQWGDLETRIYEQTTRHKMQFGEDKQLQYGTALGMPMESSGKNRGALIQGNILLSARDTIKLGSEIQNFRLNDWWPASMDTVGGMGPGTFQNINNGQRDRAAFFAEWDASWSPQWFSQLGLRSEMVKMNAGAIQGYNDRPMYADDAAAFNALDHQRTDHNLDLTALARYTASPTQTLELGYAQKTRSPNLYERYTWSAMTMAAVMNNFAGDGNGYVGNINLKPEVAHTVSATWDWHDADKEQWNLKVTPYYTYVTDYVDAQRCPLSFSSNCTVANQTATTGFVNLQYVNQTAQLYGMDVSSQMNLGEYAGYGSFVVNGVLNYTRGSNLTTGDNLYNIMPLNTKLAVVQSVGNWSNTAEWQLVAAKNRVSEVRNENQTGGYALFNLRSSYTWGNARFDIGIDNVFNRFYGLPLGGAYIGQGKTMSANGIPWGVPVPGMGRSISTAFNLKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUN2</accession>
    <name>A0A2S9GUN2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3823</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000023">
        <property type="protein sequence ID" value="PRC91408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91408">
        <property type="protein sequence ID" value="PRC91408"/>
        <property type="gene ID" value="S2091_3823"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="67" mass="7185" checksum="CA592E0C52AADF92" modified="2018-07-18" version="1">MSNTNNPSDLHMQAAVDHEEAAKHHQKASESHHHNKLDDAKGSAKSAMDCSDKAKKSSDNACASSIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUV1</accession>
    <name>A0A2S9GUV1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">tRNA threonylcarbamoyl adenosine modification protein YeaZ</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3785</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000022">
        <property type="protein sequence ID" value="PRC91507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91507">
        <property type="protein sequence ID" value="PRC91507"/>
        <property type="gene ID" value="S2091_3785"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002949">
        <property type="term" value="P:tRNA threonylcarbamoyladenosine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000905">
        <property type="entry name" value="Gcp-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022496">
        <property type="entry name" value="T6A_TsaB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11735">
        <property type="entry name" value="PTHR11735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11735:SF11">
        <property type="entry name" value="PTHR11735:SF11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00814">
        <property type="entry name" value="TsaD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03725">
        <property type="entry name" value="T6A_YeaZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TsaD" evidence="1">
        <location>
            <begin position="33"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="241" mass="25238" checksum="919E1F90BA02E14A" modified="2018-07-18" version="1">MFKILSIETSSELASAALLFGQKIIQRQTNGVTNHSQSILPMVQSLLQEAGITLSECDAIAFGSGPGSFTGVRTACGVVQGLAFGANLPVIPVVTLLALAEDCRNKTGANHVLAALDARMGEVYWAQYRYDEAQQAWATLVEPTLSAPALLVPNDVDGLALVGNGFAAYPDKFTLPVALLAAAQSAVPQAEAVARLGKIEFAAGRCYPAEQAQPLYLRNKIALTIAERAALTAANLNNGAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUW6</accession>
    <name>A0A2S9GUW6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Methyl-accepting chemotaxis protein (MCP) signaling domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_3779</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyl-accepting chemotaxis (MCP) protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000022">
        <property type="protein sequence ID" value="PRC91501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91501">
        <property type="protein sequence ID" value="PRC91501"/>
        <property type="gene ID" value="S2091_3779"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004888">
        <property type="term" value="F:transmembrane signaling receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004090">
        <property type="entry name" value="Chemotax_Me-accpt_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004089">
        <property type="entry name" value="MCPsignal_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00015">
        <property type="entry name" value="MCPsignal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00260">
        <property type="entry name" value="CHEMTRNSDUCR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00283">
        <property type="entry name" value="MA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50111">
        <property type="entry name" value="CHEMOTAXIS_TRANSDUC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0807">Transducer</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="199"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="6">
        <location>
            <begin position="220"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="domain" description="Methyl-accepting transducer" evidence="5">
        <location>
            <begin position="277"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="528"/>
            <end position="553"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00029447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC91501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="553" mass="59926" checksum="0CC8D19D67A85E7A" modified="2018-07-18" version="1">MKAADFKIGIRLGFLAGFLMFTMFGTGLAGWYTFAQMRAIDIETMNKASLLQESIDTARTAQVEFKKQVQEWKDTLLRGNDPASFDKYSKAFLKQSDLTQTNLHKLKDQFVKLGLDTKQVDETLSMHAELGVKYSTALKQYDIKNPDSSHVVDALVKGMDRPPTKKIDDIVAYVFDQSKQMMAARSTESEGRYQSGVRLQLIVILLAGSVGCVTTVLLIRSIVVPLRLAVEVAERVAEGDLTSHIEVTSKDETGQLMQALLKMNDNLLHIVNDVRISADTIAHATHEIATANMDLSGRTETQAGALEETASSMEELTSTIKQNSQNSQQANKLAQTASEIAIRGGVRMSQVVTTIGSINESSRKIVDIISVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAAEVRNLAQRSASAAKEIKELISDSVEKVEAGSKLVNQAGSTMNEVQESIQRVTDIVAEISLASREQAQGIEQIQQAISAMDDVTQQNAALVEEAAAAAASLSEQANSLTTVVSVFKLENESKNNAQSRSTFNLQQGVPRIGSKSPSGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUX7</accession>
    <name>A0A2S9GUX7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">AhpC/TSA family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3813</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000022">
        <property type="protein sequence ID" value="PRC91535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91535">
        <property type="protein sequence ID" value="PRC91535"/>
        <property type="gene ID" value="S2091_3813"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016209">
        <property type="term" value="F:antioxidant activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000866">
        <property type="entry name" value="AhpC/TSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
        <property type="entry name" value="AhpC-TSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015777048" evidence="1">
        <location>
            <begin position="25"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="2">
        <location>
            <begin position="24"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="170" mass="19579" checksum="2EE765BE49164592" modified="2018-07-18" version="1">MDRRKWLQMALAGGLASLNTSLFAQDEKNIPKFTLQGVDANGKKLELSDFMGKTVLVSFFTAGCNVCTRDLKLMREFYVSNSKRKFVLLAVNIDQNKADFDEYNQLIAQVIPQEQRFPMVWRNAPSHKDNFGTIVHQPTHFVINPKNEFIFKREGSFEPEDWDNLWSSLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GV03</accession>
    <name>A0A2S9GV03_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">EamA-like transporter family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3665</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000021">
        <property type="protein sequence ID" value="PRC91549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91549">
        <property type="protein sequence ID" value="PRC91549"/>
        <property type="gene ID" value="S2091_3665"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="63"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="94"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="117"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="144"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="176"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="201"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="235"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="261"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="4"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="292" mass="32138" checksum="47903549C562CCD4" modified="2018-07-18" version="1">MQSLWILVSSLLFALMGVCVKLASAFYTTSEIVMYRGIFGVFFLFLISRINHTSLKTRMPLRHFGRGLVGVIALWLWFYTIGKLPLAMANTLNYMSPIWIAAMLFAYNWWRGKSGFSWGLPSAIMLSFVGVILLLQPSMQPEQLPIAFISLGSGMLAALAYLQVRAMGLLGEPETRVVFYFSLTSAAAGAFAGLIDHDWHSHQLIGIVLLLLVGLLASTAQLAMTRAYRLGNPLLTANLSYSGIIFSSVLGVLIWHDKLSVLSWFGIAVIVVSGILATYIHTKLTSKLGLIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GV57</accession>
    <name>A0A2S9GV57_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3707</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000021">
        <property type="protein sequence ID" value="PRC91591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91591">
        <property type="protein sequence ID" value="PRC91591"/>
        <property type="gene ID" value="S2091_3707"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1220.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013321">
        <property type="entry name" value="Arc_rbn_hlx_hlx"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="70" mass="7839" checksum="5D1CAF6C510686E4" modified="2018-07-18" version="1">MAKVHRLRARAAEHVGSAEAEHRANLDVALRYPGKRSLAQVLSQMPNVGKDEDFVRPIELMRQGLADVFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GV81</accession>
    <name>A0A2S9GV81_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3745</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000021">
        <property type="protein sequence ID" value="PRC91629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91629">
        <property type="protein sequence ID" value="PRC91629"/>
        <property type="gene ID" value="S2091_3745"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-binding" evidence="1">
        <location>
            <begin position="30"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding_C" evidence="2">
        <location>
            <begin position="473"/>
            <end position="547"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="560" mass="61139" checksum="96E0775101FA34CD" modified="2018-07-18" version="1">MDKFWLKSYPQGVPAEVDFSKYHSLAQLMEESLKKFASRPAFVCMDKSITYAELDAMSLKIAAWLQSKGIKKGARIAIMMPNILQYPVVMLGVIRAGYTVVNVNPLYTPRELEHQLKDSGAEAIFILENFATTLEQVIAHTPVKHVVVACMGDLLGTVKGTIVNLVVRHVKKMVPAFSLPGSISFNSVLSSAARLSQNPVEFSMDDLAFLQYTGGTTGVSKGAMLTQRNIVANVIQADAWFQPALSKQPDSHQLTMVCALPLYHIFALTVCGLVGMRLGALNILIPNPRDMPGFIKELGKYKVDMFPAVNTLYNGLMNNSEFAKLDFSNLKLSMGGGMAMQKAVTERWKKITGSTICEGYGLSETSPIASAHPLDGTGVAGSIGLPLPSTELKILDDNGDEVPLGQPGEIGIRGPQVMAGYWNNPAETAKVMTADGFFKTGDIGVMDETGCTKIVDRKKDMILVSGFNVYPNEIEGVVAMHPGVLEVACVGVPDEHSGEAVKLYIVKKDPALTVQDILEYCKHELTGYKKPRHIEFRTELPKTNVGKILRRELRDEKKAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVD3</accession>
    <name>A0A2S9GVD3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">NADH:ubiquinone oxidoreductase NADH-binding (51 kD) subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_3596</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the complex I 51 kDa subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000020">
        <property type="protein sequence ID" value="PRC91658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91658">
        <property type="protein sequence ID" value="PRC91658"/>
        <property type="gene ID" value="S2091_3596"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008137">
        <property type="term" value="F:NADH dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1440.230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11540">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001949">
        <property type="entry name" value="NADH-UbQ_OxRdtase_51kDa_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011538">
        <property type="entry name" value="Nuo51_FMN-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037225">
        <property type="entry name" value="Nuo51_FMN-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019575">
        <property type="entry name" value="Nuop51_4Fe4S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037207">
        <property type="entry name" value="Nuop51_4Fe4S-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01512">
        <property type="entry name" value="Complex1_51K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10589">
        <property type="entry name" value="NADH_4Fe-4S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00928">
        <property type="entry name" value="NADH_4Fe-4S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140490">
        <property type="entry name" value="SSF140490"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142019">
        <property type="entry name" value="SSF142019"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00645">
        <property type="entry name" value="COMPLEX1_51K_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0830">Ubiquinone</keyword>
    <feature type="domain" description="NADH_4Fe-4S" evidence="6">
        <location>
            <begin position="428"/>
            <end position="473"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007523"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC91658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="516" mass="55233" checksum="177F6866114BCB55" modified="2018-07-18" version="1">MNKALIIYVPCDSSAIALGSNEVAAAIVHEAQARGIEIQLVRNGSRGMFWLEPLVEVGTDQGRIAYGPIEVEDVAGLFDAGFEKGAAHPLQLGLTEEISYLKKQERLTFMRVGITDPVSLDDYLAHEGYAGLKRAAAMSAQNIVQEVLDSGLRGRGGAAFPTGIKWKTVLNTEATDKYVVCNADEGDSGTFSDRMVMEDDPFMLIEGMTIAGLAVGAKQGYIYVRSEYPHAIAALNKAISSAYQHGYLGKDICGYGQTFELEVRKGAGSYVCGEETALLESLEGRRGIVRAKPPLPAIQGLFGQPTVINNVISLAAVPLILARGADFYKNVGMGRSRGTLPMQLAGNIKQGGLVEKAFGVTLRELLFDFGAGTASGRPIRAVQVGGPLGAYLPESKFDTPIDYEAFAAIGATVGHGGIVVFDDTVDMAKQARYAMEFCAVESCGKCTPCRIGSTRGVEAVDKIIANQDRPQQIHLLRDLCDVMVNGSLCAMGSMTPNPVLSALNYFPDDFNRKLNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVG1</accession>
    <name>A0A2S9GVG1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">NADH-quinone oxidoreductase, E subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_3632</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>2Fe-2S cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49601"/>
        </cofactor>
        <text evidence="6">Binds 1 [2Fe-2S] cluster.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the complex I 24 kDa subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000020">
        <property type="protein sequence ID" value="PRC91694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91694">
        <property type="protein sequence ID" value="PRC91694"/>
        <property type="gene ID" value="S2091_3632"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03064">
        <property type="entry name" value="TRX_Fd_NuoE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1590">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002023">
        <property type="entry name" value="NuoE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042128">
        <property type="entry name" value="NuoE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041921">
        <property type="entry name" value="NuoE_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000216">
        <property type="entry name" value="NADH_DH_24kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01958">
        <property type="entry name" value="nuoE_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01099">
        <property type="entry name" value="COMPLEX1_24K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="4 6" id="KW-0408">Iron</keyword>
    <keyword evidence="5 6" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="6">
        <location>
            <position position="83"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="88"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="124"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="128"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000216-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC91694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="173" mass="19147" checksum="D70C291ADE17E756" modified="2018-07-18" version="1">MLLSEQTYKKIDREIAKFPDDQRQSAVMAALAIAQDQTSWLPPEVLQEVADYLRMPAVAVQEVATFYNMYNTKPVGQFKITVCTNLPCALSGGEKAAHHLKHKLGIDYRETTADHKFTLMEGECMGACGDAPVMLVNNKRMCSFMSDQKIDALVDELKNTSPADASGNEGSRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVR7</accession>
    <name>A0A2S9GVR7_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 6">Signal peptidase I</fullName>
            <ecNumber evidence="3 6">3.4.21.89</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_3555</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>Cleavage of hydrophobic, N-terminal signal or leader sequences from secreted and periplasmic proteins.</text>
            <dbReference type="EC" id="3.4.21.89"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Membrane</location>
            <topology evidence="6">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the peptidase S26 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.89" evidence="3 6"/>
    <dbReference type="EMBL" id="PUGF01000019">
        <property type="protein sequence ID" value="PRC91800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91800">
        <property type="protein sequence ID" value="PRC91800"/>
        <property type="gene ID" value="S2091_3555"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006465">
        <property type="term" value="P:signal peptide processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06530">
        <property type="entry name" value="S26_SPase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036286">
        <property type="entry name" value="LexA/Signal_pep-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000223">
        <property type="entry name" value="Pept_S26A_signal_pept_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019758">
        <property type="entry name" value="Pept_S26A_signal_pept_1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019757">
        <property type="entry name" value="Pept_S26A_signal_pept_1_Lys-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019533">
        <property type="entry name" value="Peptidase_S26"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43390">
        <property type="entry name" value="PTHR43390"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10502">
        <property type="entry name" value="Peptidase_S26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00727">
        <property type="entry name" value="LEADERPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51306">
        <property type="entry name" value="SSF51306"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02227">
        <property type="entry name" value="sigpep_I_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00760">
        <property type="entry name" value="SPASE_I_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00761">
        <property type="entry name" value="SPASE_I_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_S26" evidence="7">
        <location>
            <begin position="15"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="38"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00019232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR600223-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF10502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC91800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="223" mass="24979" checksum="7AFC19A6A0479654" modified="2018-07-18" version="1">MLNFKKLVLNNKGFIAFMLGMLLFRSAVADWYVVPTSSMYPTLLIGDRVVADRLAYDVKLPFSDVILKHNADPVRGDIVTFSSPADGVRLVKRLVAVPGDVVEMRDDKLIINGQPLSYQAVATKVELTPEYVGQQLVFNENLLGKNHQIIQMPERQAIRSFGPVVVPEGQYLMLGDNRDNSADSRYIGFVKRELITGQVKRVLFSLDSGDYYLPRMNRIASGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVX5</accession>
    <name>A0A2S9GVX5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3433</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000018">
        <property type="protein sequence ID" value="PRC91877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91877">
        <property type="protein sequence ID" value="PRC91877"/>
        <property type="gene ID" value="S2091_3433"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015698140" evidence="1">
        <location>
            <begin position="20"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="141" mass="14884" checksum="9913D34F58392747" modified="2018-07-18" version="1">MKNFTQTIFFCVALFSAQAALSQVAVVVGAKSDVAALTADQVSSLYLGKTDKFPNGNTAMPLDQATGSAVRNNFYDKVTGKSEAQVKSAWSRLVFSGKGTPPKEVASSAEIKKLVTNNPNTIGYIEKSAVDSSVKVVLTSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVZ0</accession>
    <name>A0A2S9GVZ0_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Flagellar basal body protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_3382</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 4">Bacterial flagellum basal body</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the flagella basal body rod proteins family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000018">
        <property type="protein sequence ID" value="PRC91826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91826">
        <property type="protein sequence ID" value="PRC91826"/>
        <property type="gene ID" value="S2091_3382"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009425">
        <property type="term" value="C:bacterial-type flagellum basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001444">
        <property type="entry name" value="Flag_bb_rod_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020013">
        <property type="entry name" value="Flagellar_FlgE/F/G"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010930">
        <property type="entry name" value="Flg_bb/hook_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037925">
        <property type="entry name" value="FlgE/F/G-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00460">
        <property type="entry name" value="Flg_bb_rod"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06429">
        <property type="entry name" value="Flg_bbr_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117143">
        <property type="entry name" value="SSF117143"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03506">
        <property type="entry name" value="FlgEFG_subfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0975">Bacterial flagellum</keyword>
    <keyword evidence="7" id="KW-0966">Cell projection</keyword>
    <keyword evidence="7" id="KW-0969">Cilium</keyword>
    <keyword evidence="7" id="KW-0282">Flagellum</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flg_bb_rod" evidence="5">
        <location>
            <begin position="5"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="domain" description="Flg_bbr_C" evidence="6">
        <location>
            <begin position="171"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU362116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF06429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC91826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="246" mass="26171" checksum="9FC2D2B2CFB7DD3B" modified="2018-07-18" version="1">MDKLIYTAMTSGKHTMAQMDTVSHNLANISTDGFRAQLDSFRAVPVLSTDLPVQTFVVDATVATNFDQGVTHTTDRTLDVSVQGHGWLVVEDANGKEAYTRAGSLKTDQNGVLQTQRGLNVLSDSGAITLPPDETITISKDGTISSIPIGNKVANGTIVGQLKLVNPPENTLVRGDDGLFRAKDGTVADADINVTVLSGSIENSNVNPVESLVNMITLARMFDMHIQLLTDAQTDDAKASTIMALS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GW56</accession>
    <name>A0A2S9GW56_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fimbrial protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3294</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000017">
        <property type="protein sequence ID" value="PRC91952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91952">
        <property type="protein sequence ID" value="PRC91952"/>
        <property type="gene ID" value="S2091_3294"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009289">
        <property type="term" value="C:pilus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007155">
        <property type="term" value="P:cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1090">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000259">
        <property type="entry name" value="Adhesion_dom_fimbrial"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036937">
        <property type="entry name" value="Adhesion_dom_fimbrial_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008966">
        <property type="entry name" value="Adhesion_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00419">
        <property type="entry name" value="Fimbrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49401">
        <property type="entry name" value="SSF49401"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015715164" evidence="1">
        <location>
            <begin position="25"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="domain" description="Fimbrial" evidence="2">
        <location>
            <begin position="204"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="349" mass="36867" checksum="C32E659771139CFB" modified="2018-07-18" version="1">MIKFTTVLNFILCVLAFSASNALATNVCKLTQSTFQMPFSLSVAQDAPVGTQIGPDIETGPLQLYTCTGNYSSQSLGLKPIGGVLHGMINGRRVFKTGIAGIGYALGLRSIGNCDGSSAYLDGVEFTSERLGPLNRLFCTYPGLMPVQPMRGQFLLAFYKIGATNGGSLASYVVGASVIRNNQSYWENPNSSTESKLTIKGLAVTTVSCSLSDIVVPMGDTNTQQMFNGVGSRLNPVPFTIHLNNCRAGPNTSVKYQFDPLMPAFDAKNGILALNAGGARRLAATGIGIEIRAAGGTEAVQAFGVPHVFGKITTGENYTIPLNARYIQTAAKITGGIANSAMTFTLIYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GW80</accession>
    <name>A0A2S9GW80_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">SoxA: sarcosine oxidase, alpha subunit family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_3312</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GcvT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000017">
        <property type="protein sequence ID" value="PRC91970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91970">
        <property type="protein sequence ID" value="PRC91970"/>
        <property type="gene ID" value="S2091_3312"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008115">
        <property type="term" value="F:sarcosine oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046653">
        <property type="term" value="P:tetrahydrofolate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.440">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042204">
        <property type="entry name" value="2Fe-2S-bd_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041854">
        <property type="entry name" value="BFD-like_2Fe2S-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028896">
        <property type="entry name" value="GCST/YgfZ/DmdA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013977">
        <property type="entry name" value="GCV_T_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006222">
        <property type="entry name" value="GCV_T_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029043">
        <property type="entry name" value="GcvT/YgfZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006277">
        <property type="entry name" value="Sarcosine_oxidase_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041117">
        <property type="entry name" value="SoxA_A3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027266">
        <property type="entry name" value="TrmE/GcvT_dom1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43757">
        <property type="entry name" value="PTHR43757"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01571">
        <property type="entry name" value="GCV_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08669">
        <property type="entry name" value="GCV_T_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17806">
        <property type="entry name" value="SO_alpha_A3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037980">
        <property type="entry name" value="SoxA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101790">
        <property type="entry name" value="SSF101790"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01372">
        <property type="entry name" value="soxA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyr_redox_2" evidence="4">
        <location>
            <begin position="170"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="domain" description="SO_alpha_A3" evidence="6">
        <location>
            <begin position="526"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="domain" description="GCV_T" evidence="3">
        <location>
            <begin position="625"/>
            <end position="890"/>
        </location>
    </feature>
    <feature type="domain" description="GCV_T_C" evidence="5">
        <location>
            <begin position="916"/>
            <end position="1001"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF08669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF17806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC91970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="1009" mass="109222" checksum="83B5E65F739F8291" modified="2018-07-18" version="1">MNSHRINKPNSRINREQALSFTFDGKSYQGFAGDTLASALLANGVRMIGRSFKYGRPRGIVGHGAEEPNALIQLEKGAVTTPNVKATQVELYEGLNAFSTTGWPSLNFDVKSVMGRAARFMPAGFYYKTFMAPPKMWPLYEDVIRRAAGFGSAPVDPDPEYYDHLHHHPDVLVVGGGACGIWSALIAARAGLRVMLVDEQAEMGGWLLSDGDAIIDSYPTHTWLRSCIAELDQMSNVTRLPRTTAFALHDANLVQAVELIQDHLSLNARNAELPRQRLHKIRANQVILATGALERPLVFGNNDLPGVMTASAGQTYLNRYSVRAGKKVLVMTSNDWAYGAACDLAQAGAEVTLADTRVNGALPARSKAAQQAGVTILNGHGIAHAVGGRAVMGAHLIKLDPVMNQAIGSGAEVACDLLLSSGGLSPNVHLFCHNGSRPSWSEEKLAFVAPEQGRKGISCVGSVVGEFSLQDAIAQTTQVVTALCSSLGKTVSVAQPKVEGSKMPVNAAPARRIFRVPDGKREGHGKKAFVDYQNDVAASDIELAVRENYRSIEHVKRYTGLGFGTDQGKLSNVNGFAIAADALGKSIAEVGTTTYRPAYTPVAFGALAGAMVGDTFDPSRYSAIHEAHVKRDAKFEVVGQWMRPWYFPKGSEDLHAAVNRECLAARNGVGMMDASTLGKIDIRGPDAREFLNRVYSNAWSQLAPGKCRYGLMLDENGMVMDDGVTACLDDQHFMMTTTTGGAARVMSWLERWLQTEWPDLKVYLTSVTDHWSTSAVVGPKSRAVLEKLCTDIDLSADAFKFMDCRIGTVAGVPARVFRISFSGELAYEVNVDASYGHYMWEALMKAGEEFEITPYGTETMHVLRAEKGFIIVGQDTDGSVSPIDLGMAWAVSMKKSFAFLGKRSLARTDTARTDRKQLVGLMTEDPNVVLTEGAQIVESAQVGPMEHMIGRVTSSYHSAFLGRSIAMALVEGGSAKDGQVLYCWDGGKITKAKIVSPVFIDPEGKRQHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWD8</accession>
    <name>A0A2S9GWD8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3182</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000016">
        <property type="protein sequence ID" value="PRC92047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92047">
        <property type="protein sequence ID" value="PRC92047"/>
        <property type="gene ID" value="S2091_3182"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="115" mass="12710" checksum="B3F8E1D7DA5572C4" modified="2018-07-18" version="1">MATTVNFTGSVDRDLLKRVKIIAAKTDTSINALFNAELRYLVETFEAAEAGNNQNFRTLLDFSLGRIDDVAVMTQLGITGAEDLFLLMAQSHLPMPRLPEEVTQSMANDLHTLLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWG9</accession>
    <name>A0A2S9GWG9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3195</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000016">
        <property type="protein sequence ID" value="PRC92060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92060">
        <property type="protein sequence ID" value="PRC92060"/>
        <property type="gene ID" value="S2091_3195"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021847">
        <property type="entry name" value="DUF3443"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11925">
        <property type="entry name" value="DUF3443"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015534971" evidence="1">
        <location>
            <begin position="28"/>
            <end position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="430" mass="43690" checksum="625415E23B341AC1" modified="2018-07-18" version="1">MNRSISIKSNRLISIALPLLLALLMSACGGGGSSSSSSSSSSSSGSTTPTPAQNTVAVSVDSNVFGALNEPFVSVTLCSPTAPTTCMTIDHILVDTGSTGLRVFAQPANAAALSTLNLTQQTVAGNPVVECLTFVQGYTWGPIKSANIQIGGETAKNVAIQVMADPGFTDTSACSGSNSSSTNINTPALFAANGVLGVGLALQDCGPACISASNVENVYFSCSTTGTNCVNIGLPVANQVQNPTSLFATDNNGVILTLNTVPAAGAVSATGTLTFGIDTQADNVSANSNLLLLNNIGNFTTVFEGQTYLNSYIDSGSNGLFFNAPASNPITECTGNTQYFYCPASTLSLTASLSGVAGSTAAATVNFAVANTNTLVNNNDAAYINLGGTAADTPQGLTFDWGLPFFYGKSVYVVIEGSTTKKGTGPYFGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWH0</accession>
    <name>A0A2S9GWH0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3199</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000016">
        <property type="protein sequence ID" value="PRC92064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92064">
        <property type="protein sequence ID" value="PRC92064"/>
        <property type="gene ID" value="S2091_3199"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="SSF54001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="16"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="380" mass="43758" checksum="16DCD785E56B124E" modified="2018-07-18" version="1">MKFFWISLLALLRPIYFFYSFCCLFLPIFILYGAGSIFYPSYLPLPVSVIKLGIQVMLGGFVVVMLVIPILVQLRKSKDDSDPFQSAFMSWFATLRWYWNTTPGPMAKVGLPSGYLVENPMSYRLTAQDMREILSRIQPGDILLRAYDGYMDGDFIRLSSLCSKNGYHPGWFTHVAMYAGPLNENDRANVPAHFRNNKKYFQEGPQMIIHSMAMGVHTEDILTWFRCDYLVVLRLKPDLTMTHKVELPQPRHRKHSASELTSQKIKDELRKGAPINHDEVIQNAKLSALEKIGEPYDFECVETNKFDRFSCAELIYYCFRSAHDALGLFPQLHALYPLGKLNRHWSIMGRSTVTPDDFYGLAKAQHLDVIWIDEISKKNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GX84</accession>
    <name>A0A2S9GX84_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Oxidoreductase molybdopterin binding domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2991</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92332">
        <property type="protein sequence ID" value="PRC92332"/>
        <property type="gene ID" value="S2091_2991"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000572">
        <property type="entry name" value="OxRdtase_Mopterin-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036374">
        <property type="entry name" value="OxRdtase_Mopterin-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00174">
        <property type="entry name" value="Oxidored_molyb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56524">
        <property type="entry name" value="SSF56524"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Oxidored_molyb" evidence="1">
        <location>
            <begin position="26"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="212" mass="24553" checksum="9ADF46F8BD424FC3" modified="2018-07-18" version="1">MHKKTTPNIEKKPSSLRYFQEGPSDINLKNWKLKISGEVSNELSISYDDILKLPKSYFHRRSVCVCLWSIKRHWEGVLLSDVLALAGVDKNDDKLFMKQISHPTDKGVYDSTVHLSSALKRNAILAYEVDGEILKSEQGFPLRFLDFGLFLYKCVKSVSEIKITRENKLGYWEDYAGYDLDGTIQPKRYYAVDLHKKFYFDGNGEVFDHDIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXA5</accession>
    <name>A0A2S9GXA5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="10">RarD: protein RarD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">S2091_2999</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the EamA transporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92340">
        <property type="protein sequence ID" value="PRC92340"/>
        <property type="gene ID" value="S2091_2999"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004626">
        <property type="entry name" value="RarD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22911:SF114">
        <property type="entry name" value="PTHR22911:SF114"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00688">
        <property type="entry name" value="rarD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="32"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="61"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="93"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="117"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="140"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="168"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="206"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="236"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="260"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="9">
        <location>
            <begin position="2"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC92340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="294" mass="32256" checksum="66F4DBB780BF37F9" modified="2018-07-18" version="1">MAACSYSVWGLFPLYFKSISNVAPMEILAHRILWAMPFLLLIIACRTQWAWIPNVIKRPKVLGGFIASALLLSCNWFIYIWAVNNGHVIDSSLGYFINPIVNVLLGFILLKERLRPIQWLAVGIAGCGVSWLALQSGHMPWISLALAISFGIYGLLRKTAALGALEGLSLETIILFPCALAYVTYLSSQGASTFTTTLAIDSTTTWLLLAAGPITAIPLLLFAAGARLIPMSTLGLLQYIAPSIQLLLGVWLFHEPFNGARLAGFVIIWSALILYSAEGLWRAYQQNKQRMAAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXD7</accession>
    <name>A0A2S9GXD7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">RHS repeat-associated core domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3043</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92384">
        <property type="protein sequence ID" value="PRC92384"/>
        <property type="gene ID" value="S2091_3043"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022385">
        <property type="entry name" value="Rhs_assc_core"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03696">
        <property type="entry name" value="Rhs_assc_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="181" mass="19784" checksum="F18AF372964D8D26" modified="2018-07-18" version="1">MYGKSASGSSLDAETNLNQNYFRDYDPTTGRYNESDPLGFGGGQLSTFAYVGANPLAWTDSQGLANSGLMIDVPGTNYIVRIDPPHVPGQQRHAHIYDDNKNLITAISEDGTGSHGQCPKKLPKNKKLLKYLLGKGIAISFAGDLLFLYDLVTDVGRSVDPYNPYYYSDPNDVPTPDYVPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXF7</accession>
    <name>A0A2S9GXF7_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7 10">Phosphoglycerate kinase</fullName>
            <ecNumber evidence="2 7 10">2.7.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">pgk</name>
        <name evidence="11" type="ORF">S2091_2777</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7 10">
            <text>(2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP</text>
            <dbReference type="Rhea" id="RHEA:14801"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57604"/>
            <dbReference type="ChEBI" id="CHEBI:58272"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.2.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 2/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7 10">Belongs to the phosphoglycerate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.2.3" evidence="2 7 10"/>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92402">
        <property type="protein sequence ID" value="PRC92402"/>
        <property type="gene ID" value="S2091_2777"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00185"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004618">
        <property type="term" value="F:phosphoglycerate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1260">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00145">
        <property type="entry name" value="Phosphoglyc_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001576">
        <property type="entry name" value="Phosphoglycerate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015911">
        <property type="entry name" value="Phosphoglycerate_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015824">
        <property type="entry name" value="Phosphoglycerate_kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036043">
        <property type="entry name" value="Phosphoglycerate_kinase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11406">
        <property type="entry name" value="PTHR11406"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00162">
        <property type="entry name" value="PGK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000724">
        <property type="entry name" value="Pgk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00477">
        <property type="entry name" value="PHGLYCKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53748">
        <property type="entry name" value="SSF53748"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00111">
        <property type="entry name" value="PGLYCERATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="5 7 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7 10" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="7 8">
        <location>
            <begin position="25"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="7 8">
        <location>
            <begin position="64"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7 8">
        <location>
            <position position="41"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 8">
        <location>
            <position position="118"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 8">
        <location>
            <position position="151"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 9">
        <location>
            <position position="202"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 9">
        <location>
            <position position="324"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 9">
        <location>
            <begin position="350"/>
            <end position="353"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000724-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000724-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC92402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="397" mass="41365" checksum="531755104E1FCB4D" modified="2018-07-18" version="1">MQFIRFSDLVAQGSLAGKRVFIRADLNVPQDDQGNITEDTRIRASVPAIQQALQAGAAVMVTSHLGRPTEGTLRAEDSLAPVAHRLSELLGQPVTLLQNWLDGVQVQPGQVVLLENCRVNIGEKKNNLELAKKMAALCDVYVNDAFGTAHRAEATTHGIAQFAPVACAGPLLTAELDALGRALGQPARPLVAIVAGSKVSSKLTILKSLADKVDNLIVGGGIANTFMLAAGLNIGKSLAEADLLDEARAIMEIMSKRGATVPIPVDVVCAKEFSPNAVATVKLVADVEADDMILDIGPQTAAQLATQISTAGTIVWNGPVGVFEFDQFGHGTKTLALAIANGAGFSVAGGGDTLAAIAKYEIADKIGYISTGGGAFLEFLEGKTLPAVEVLMQRAAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXG2</accession>
    <name>A0A2S9GXG2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major Facilitator Superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_2789</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92414">
        <property type="protein sequence ID" value="PRC92414"/>
        <property type="gene ID" value="S2091_2789"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="22"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="60"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="91"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="116"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="152"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="185"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="250"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="283"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="316"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="341"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="373"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="407"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="26"/>
            <end position="431"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC92414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="433" mass="47370" checksum="9CA6634C27C37582" modified="2018-07-18" version="1">MNQNRVNSADIAGFEAATYAKVTWRLMPILFLCYVAAYLDRVNVGFAKLQMLSDLNFSETVYGLGAGVFFIGYFLFEIPSNIILHKVGARIWIARIMITWGLISGAMIFVNSATMFYLMRFLLGVAEAGFFPGVILYLTYWYPAERRGKITAMFMTAVAISGVVGGPVSGWVMHSMPGIYGLTGWQWMFIIEALPSLVLGVVVIFYLQNHIVDAKWLSADEKQLLAKNVQTEAATKQEMSFKQVMTHPKIWHMAFIYFSFIMGLYGISFWLPTIIKATGVKDTLDIGLLTAIPYAAAAVGMVLIGRSADKNRERRWHVVIPALLGCAGLLLSTIYGHNTLLAMAALTLATIGILTTLPLFWSLPTAFLGGAAAAAGIALINSLGNLAGFVSPYLVGWLKDLTHSTDSGMYLLAASLVIGAVLTLMVPKEMVNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXK6</accession>
    <name>A0A2S9GXK6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Thiamine pyrophosphate-requiring enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_2827</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the TPP enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92452">
        <property type="protein sequence ID" value="PRC92452"/>
        <property type="gene ID" value="S2091_2827"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044281">
        <property type="term" value="P:small molecule metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012000">
        <property type="entry name" value="Thiamin_PyroP_enz_cen_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012001">
        <property type="entry name" value="Thiamin_PyroP_enz_TPP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011766">
        <property type="entry name" value="TPP_enzyme-bd_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02775">
        <property type="entry name" value="TPP_enzyme_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00205">
        <property type="entry name" value="TPP_enzyme_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02776">
        <property type="entry name" value="TPP_enzyme_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="SSF52467"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0786">Thiamine pyrophosphate</keyword>
    <feature type="domain" description="TPP_enzyme_N" evidence="5">
        <location>
            <begin position="4"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="domain" description="TPP_enzyme_M" evidence="3">
        <location>
            <begin position="191"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="domain" description="TPP_enzyme_C" evidence="4">
        <location>
            <begin position="381"/>
            <end position="528"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU362132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC92452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="564" mass="60681" checksum="414E8AF1D227CF17" modified="2018-07-18" version="1">MQKTVAELLVATLHEIGVRQIFGVVGDALNPLTDAIRRHGGMQWIGVRHEEGAALAAAGQAKLTGKLAVCCGTTGPGANHLIAGLYEAHKDHAPVLAISGGVPATQRGNDYLQENTPDLLFRDVTVYTQTLANPDQASHVFHQAIAHAYGMRGVSHLNIPPEVFAAKTGAKMASLATLRESPEMAADPKDVTEAVRLIGHSANIAIFAGAGCRSAIPQVLQLAERLQSPIMHTFRAKDMVAYNHPHWIGGVGLIGGAPGVDALQDAELVLMLGSDYPYTEFLPENGKVIQIDLRPEVLGRRTGVQLGIVGAIKPTITQLLEQLPQRKDGDFLQKVTAARKKWDQMLDKKALLRESLEHINPQALVRGISRFAQSDATFIVDTGIVTLWCGNWLQQSGQQRILASFNNAAVGTSLGQANGVQALNRDKQVIVAVGDGGFTMLLGEFMTSVEHHLPVKVIVFNNKEWGLVHLEMEVAGLPAHKGSKFPNIDFAAFAKACGVSGFTVQNSGDLESGLNQLFAVTGPAVLNVFIDPAELPSMPHIHIDQVWRFGLARVKEAILSIRDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXN2</accession>
    <name>A0A2S9GXN2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DJ-1/PfpI family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2843</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92468">
        <property type="protein sequence ID" value="PRC92468"/>
        <property type="gene ID" value="S2091_2843"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032633">
        <property type="entry name" value="ThiJ-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17124">
        <property type="entry name" value="ThiJ_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="298" mass="33858" checksum="4281001E16ECD969" modified="2018-07-18" version="1">MEKRHIIIPLPQHDFDPTEVAVTWRILRDAGCEIDFATVDGKRGYADPLMISGQGLDPWGWIPLLNKIRLVGLFLRADHFGREAYRELEADARFLKPKRFEELAVADYDALVLPGGHAQGMKPYLENARLQNFVADFFDTCDATGQHKPIAAICHGVLLAARSISKKTNKSALYGKKTTALTWKLESSAWNLTKYLARFWDPNYYRTYLESGNEAVGYWSVEQEIKRALAKEGDFLDVPKGTQHHFLKTSGLVRDRLNNSQAAWVVRDGTYVSGRWPGDVHTFAQQFVAVLNEYYQCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXP5</accession>
    <name>A0A2S9GXP5_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RTX toxin-activating lysine-acyltransferase</fullName>
            <ecNumber evidence="2">2.3.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2856</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Involved in fatty acylation of protoxin at internal lysine residues, thereby converting it to the active toxin.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the RTX toxin acyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="2"/>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92481">
        <property type="protein sequence ID" value="PRC92481"/>
        <property type="gene ID" value="S2091_2856"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019835">
        <property type="term" value="P:cytolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009404">
        <property type="term" value="P:toxin metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003996">
        <property type="entry name" value="RTX_toxin-activating_protC_bac"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02794">
        <property type="entry name" value="HlyC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2" id="KW-0204">Cytolysis</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU368102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="157" mass="17922" checksum="A6C836799282065D" modified="2018-07-18" version="1">MAVGFDAPSDSLKNRSELFGYALILMRASPAHRDQPLSKLYKIIEAAISHKTIKFYFNEDGNVVACVIWALLAEDVEHRVIQTGEFSLHESEWNEGNSLWIIELLAPFGNMNYVYRALRDSLFLTHQTVRYIRKVGQEVLIKEAVRRPLIVTNSDGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXR1</accession>
    <name>A0A2S9GXR1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2889</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92514">
        <property type="protein sequence ID" value="PRC92514"/>
        <property type="gene ID" value="S2091_2889"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="105" mass="12050" checksum="376C09DDE8156A1C" modified="2018-07-18" version="1">MITVLISFNLAPGTTRTDALHIYRNSAKKWASNVDLIEKYYYFDEQTLLGGGVYIWKSIEAARQWHGPDYVAMVESVYGNAPRIQILDTLIHIEPTTRRIVEYGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXR2</accession>
    <name>A0A2S9GXR2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major Facilitator Superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_2890</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92515">
        <property type="protein sequence ID" value="PRC92515"/>
        <property type="gene ID" value="S2091_2890"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="28"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="62"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="94"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="119"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="153"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="184"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="214"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="246"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="286"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="313"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="347"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="372"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="444"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="28"/>
            <end position="468"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC92515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="486" mass="50887" checksum="01DF390D7CD9D6E2" modified="2018-07-18" version="1">METDTNSQLAVASPQTKTDNNGAAQRRVLMATAISYVVVLLDTSIVNVALDRISVSLGTQIAGLQWVMNAYILAFASLLLSGGTLGDRWGARNIYLAGLVVFTLASAVCGLAPDLPSLIVARILQGAGAAMLVPCSLKLINHAFPIPVQHARAVGIWIGCGGVAMAAGPLIGGVLIHWFDWRSIFFVNVPIGLIGIGMTWRIAPDARLLTLRRFDPVGQITAIVALAALIAALIEGHALGWNSPLILAGLAVTVVAGTIFIWVEARSSDPMLPLSFFKNGIFTGSTCVSMASAFVFYGLLFVCSLYFQRSRGNSPLVAGFAFLPMTAMVAAGSIVSSRVVTICGTHWSMCGAFGCYAAGALGMLWVDQISPYWLAVAPMVAIGLASGFISPAATAPAMGTVDKNRSGVAAAVLNSARQTGAALGVAIFGSLIAALHPFEVGMHAALWTAAAVSLIAALTWWFILEQSPLRQTRQEGSCAAQEKRRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXX0</accession>
    <name>A0A2S9GXX0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Collagen triple helix repeat (20 copies)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2881</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92506">
        <property type="protein sequence ID" value="PRC92506"/>
        <property type="gene ID" value="S2091_2881"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008160">
        <property type="entry name" value="Collagen"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01391">
        <property type="entry name" value="Collagen"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0176">Collagen</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015773007" evidence="2">
        <location>
            <begin position="19"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="83"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="114" mass="10423" checksum="DA0EED50754D0432" modified="2018-07-18" version="1">MKHSNLLAALITTAALCACEKPIVTPAPAPAHATSPTTIVIAGPAGATGATGASGADGSNGATGNTGNDGANGKDGANGTNGAAGATGATGNDGNKGDTGKTGGDTVVIVPAQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GY02</accession>
    <name>A0A2S9GY02_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Isocitrate lyase</fullName>
            <ecNumber evidence="1">4.1.3.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Isocitrase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Isocitratase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_2659</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>D-threo-isocitrate = glyoxylate + succinate</text>
            <dbReference type="Rhea" id="RHEA:13245"/>
            <dbReference type="ChEBI" id="CHEBI:15562"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
            <dbReference type="EC" id="4.1.3.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="8">Can also use Mn(2+) ion.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.3.1" evidence="1"/>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92604">
        <property type="protein sequence ID" value="PRC92604"/>
        <property type="gene ID" value="S2091_2659"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004451">
        <property type="term" value="F:isocitrate lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019752">
        <property type="term" value="P:carboxylic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00377">
        <property type="entry name" value="ICL_PEPM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039556">
        <property type="entry name" value="ICL/PEPM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006254">
        <property type="entry name" value="Isocitrate_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018523">
        <property type="entry name" value="Isocitrate_lyase_ph_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_Kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21631">
        <property type="entry name" value="PTHR21631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00463">
        <property type="entry name" value="ICL"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001362">
        <property type="entry name" value="Isocit_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="SSF51621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01346">
        <property type="entry name" value="isocit_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00161">
        <property type="entry name" value="ISOCITRATE_LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="89"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="189"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="310"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="188"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="150"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="225"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="344"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00017446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00031022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00031921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR001362-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR001362-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR001362-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC92604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="432" mass="47242" checksum="EDDD33D6A65E8879" modified="2018-07-18" version="1">MLTREQQIAELQKDWDTNPRWIGIKRNYTAADVVRLRGSIAVEHTLAKNGAVKLWNLVNNEPFVNALGALTGNQAMQQVKAGLKAIYLSGWQVAGDANVAGEMYPDQSLYPANSVPLVVKRINNTLTRADQIQWSEGTGDIDYFAPIIADAEAGFGGVLNAYELMKSMIDAGAAGVHFEDQLASVKKCGHMGGKVLVPTREAVEKLNAARLAADVMGVPTVLLARTDAEAADLITSDVDNNDKPFLTGERTVEGFYKTKPGLAQAISRGLAYAEYADMIWCETGKPDLEFAKEFADAIHAKFPGKLLSYNCSPSFNWKKNLDDVTIAKFQKELGAMGYKFQFITLAGFHALNYGMFNLAHGYARRQMSAFVELQEAEFAAAEKGFTAVKHQREVGTGYFDAVTQVIQQGVSSTTALHGSTENEQFFDNKKVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GY15</accession>
    <name>A0A2S9GY15_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2656</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92601">
        <property type="protein sequence ID" value="PRC92601"/>
        <property type="gene ID" value="S2091_2656"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025516">
        <property type="entry name" value="DUF4404"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14357">
        <property type="entry name" value="DUF4404"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="89" mass="9820" checksum="CF4CA0CB92D16432" modified="2018-07-18" version="1">MSTEQLKESLKKLHENLNGTDQVDAELSALLTVLSQDIHQLLSKERPEEDSLSNLGDRTLALSAKFAAQNPHLELGLRELGDILARMGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GY73</accession>
    <name>A0A2S9GY73_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2718</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92663">
        <property type="protein sequence ID" value="PRC92663"/>
        <property type="gene ID" value="S2091_2718"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="150"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="182" mass="19799" checksum="1C2F372DA9ABAB66" modified="2018-07-18" version="1">MQKTCGAKTRSGGKCQKAPLIGKTRCKLHGGLSTGNPNAKGNQSATKHGIYSDLIHADDLSVVDDVKSASGKIEDELLIARLQLRRALKAQANADALLDGMEVFETIEREGAELVSAKSEIKKKLRDYPQIIDRILARIESLEKTRVELAKTNGGKDDADSITRDDTVILKPDEPIPEKPVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYC7</accession>
    <name>A0A2S9GYC7_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 6">dTDP-4-dehydrorhamnose reductase</fullName>
            <ecNumber evidence="4 6">1.1.1.133</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_2438</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>dTDP-beta-L-rhamnose + NADP(+) = dTDP-4-dehydro-beta-L-rhamnose + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:21796"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57510"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:62830"/>
            <dbReference type="EC" id="1.1.1.133"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="6">Binds 1 Mg(2+) ion per monomer.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 6">Carbohydrate biosynthesis; dTDP-L-rhamnose biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 6">Belongs to the dTDP-4-dehydrorhamnose reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.133" evidence="4 6"/>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92708">
        <property type="protein sequence ID" value="PRC92708"/>
        <property type="gene ID" value="S2091_2438"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00124"/>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008831">
        <property type="term" value="F:dTDP-4-dehydrorhamnose reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019305">
        <property type="term" value="P:dTDP-rhamnose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005913">
        <property type="entry name" value="dTDP_dehydrorham_reduct"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029903">
        <property type="entry name" value="RmlD-like-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10491">
        <property type="entry name" value="PTHR10491"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04321">
        <property type="entry name" value="RmlD_sub_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0521">NADP</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RmlD_sub_bind" evidence="7">
        <location>
            <begin position="3"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU364082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC92708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="285" mass="31175" checksum="4036062CB8909CBA" modified="2018-07-18" version="1">MNKVLVLGISGMLGNAVFRLLSSNSDLMVHGTSRTSAVVKYFSDGVKEKIICGVDVESSDGLVKLFASVKPDVVINCIGLVKQLAEAKDVLSAIPINTLLPHRLAHLCAVAQARLVHISTDCVFDGQRGNYVEQDKSDAEDLYGKSKFLGEVDYPHAITLRTSIIGHELNGAHSLVNWFLKQEGGIKGYTRAIFSGLPTVELARVINDFVLPNPQLSGLYHVSAEPISKYDLLKLISAEYGKQIDIAADDQLVLDRSLDSSRFKTATGYVPPTWSELVARMREFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYC8</accession>
    <name>A0A2S9GYC8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Phage integrase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_2454</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92724">
        <property type="protein sequence ID" value="PRC92724"/>
        <property type="gene ID" value="S2091_2454"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044068">
        <property type="entry name" value="CB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002104">
        <property type="entry name" value="Integrase_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010998">
        <property type="entry name" value="Integrase_recombinase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00589">
        <property type="entry name" value="Phage_integrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51900">
        <property type="entry name" value="CB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51898">
        <property type="entry name" value="TYR_RECOMBINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0229">DNA integration</keyword>
    <keyword evidence="3" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="2 4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core-binding (CB)" evidence="6">
        <location>
            <begin position="59"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="domain" description="Tyr recombinase" evidence="5">
        <location>
            <begin position="166"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC92724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="340" mass="39154" checksum="4D20B056C65E7EC2" modified="2018-07-18" version="1">MPTIRKRGEYQWEVQVRRKGYPPQSKTFTSRADAELWGATVESEIGRGVFIDRSDAERHTVGDAIDRFKSEFAPFHYKARDDKKEAWRFQCEHLKRDLGKYSLAALDPKMVAHYRDKRLATVGESTVRKELFMLSKILKFVEMECGITLPRGNPVGKIRKPSERKHRDRRLTDDEWLRLNLECKRSQNKFLCPAMEFALETGMRQGELLALSWQDLDRKRSIVLLKDTKNGEERAVPLSPDALKVLDNLIVSIRGKIFPLQRVTLFGAFKAACVRAEVKDFKWHDLRHEGLSRLAERGDLNVLEIAAVSGHKTLSMLKRYTHLQAEKLAVKLAATASRSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYF6</accession>
    <name>A0A2S9GYF6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2460</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92730">
        <property type="protein sequence ID" value="PRC92730"/>
        <property type="gene ID" value="S2091_2460"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="195"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="237" mass="26991" checksum="80078450972E3AC8" modified="2018-07-18" version="1">MKSLALSKILSKVNPVHWTRKILLTLLTSVALWVIGISISAIPNWEPTRFAIDSNSNVFRSPEFSVDLNDLYKIGIEFNLSNGDKVDCFLEDGIESENCHLNHHLNAEWILYSDGYEINHGFSRDKVKLGGNTMGQGGWSGRNLEFRNIGEFRGARNNKYILEVRFLDNIAEIMPTKPKVVVAMNYWSRIGYMDLAGIFELLSFIMFAVTIFLIINRVWHNRGELKKVDSIAGKQAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYP6</accession>
    <name>A0A2S9GYP6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative esterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2574</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92844">
        <property type="protein sequence ID" value="PRC92844"/>
        <property type="gene ID" value="S2091_2574"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000801">
        <property type="entry name" value="Esterase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00756">
        <property type="entry name" value="Esterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015758746" evidence="1">
        <location>
            <begin position="27"/>
            <end position="538"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="538" mass="58882" checksum="155A05BF8EA080B7" modified="2018-07-18" version="1">MRPHSFGSRFIAAALAGLLSCSLVSAAESIQAAAPASATNKTEHVMIRVQTAATVGEPLSGRLLIFLKPGTGAKEVDSDIFNISATQIAAKDVSDVAPGASVLLDADDIAFPAGFSHLPAGKYQAQAVLDVDRSYNYGGRNKKHWISDVVTINWTPGGAFPAMTLVRHPEEDPRRIAERKAILAKVKPDVVREEHFTSPLLSRFWGSPKQLNAWVILPPGYDNKVNKSYPTVYWTHGFGGNFDYSLNSGLKIRERMDSGQIPPMIWVMLDESIPQGTHEFADSVNNGPWGAALTTEFIPYLEQHYRMDAVANSRFLNGHSSGGWATLQLQVNYPKTFGGTWSTSPDPSDFHDFTGPNLYAPNANIYHRADGSDYPIMRMDGKVIATLSQFSRMEEVIGPYGGQIASFDWVFSPKGEDGKPLPMFNRQTGVVDPKVVAYWHDHYDLANIVQKNWATSGADLQGRIHLYVGTADTFYLDGAAHRMQAVLDGLNAGAQFTFLPGRSHFDVYAVGDDKSGLTNQIAKEMYAVARPGVSWGKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYW4</accession>
    <name>A0A2S9GYW4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2342</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92925">
        <property type="protein sequence ID" value="PRC92925"/>
        <property type="gene ID" value="S2091_2342"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015431193" evidence="1">
        <location>
            <begin position="33"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="244" mass="27443" checksum="FFAFC0047511075F" modified="2018-07-18" version="1">MTKLNACKILLKFSWILLFAACSSTSMPNKNASPPATRILDLESAQTLVKSERFDSASQLGAMRPTANQEIESIKFELLDPTGEHLNNSVMHFAKLPNNLEFAYHSFPATKDMAELNQSFIHVFGLASVLNWSSRFPEHELPSPDQVQLISGKLFSISSKFTIEQRLSEKDIFTTECVPQDLFPASKINALLTGNATVFVCKTPIINNVTSYWYIENSARYVISEIWDDGELQSKFKIVDLTLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZ16</accession>
    <name>A0A2S9GZ16_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF4124 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_2370</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92953">
        <property type="protein sequence ID" value="PRC92953"/>
        <property type="gene ID" value="S2091_2370"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025392">
        <property type="entry name" value="DUF4124"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13511">
        <property type="entry name" value="DUF4124"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015599727" description="DUF4124 domain-containing protein" evidence="3">
        <location>
            <begin position="20"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4124" evidence="4">
        <location>
            <begin position="17"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="58"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="86"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="67"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC92953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="153" mass="16982" checksum="412FE71ACC386828" modified="2018-07-18" version="1">MKQLLISALILISVNWAHADSDIFVCVDANGVKTFGNVGEGKGCKKVDLPGLNTFPAPTAKKVGKAPGDFPKIDDSTQKKRDAERRQILSDELKAEQKKLADLNAQYNNGEPERQGGERNYAKYQERTENLKEDVNRAQQNVDALQREINGLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZ47</accession>
    <name>A0A2S9GZ47_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Prephenate dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2421</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC93004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93004">
        <property type="protein sequence ID" value="PRC93004"/>
        <property type="gene ID" value="S2091_2421"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008977">
        <property type="term" value="F:prephenate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004665">
        <property type="term" value="F:prephenate dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006571">
        <property type="term" value="P:tyrosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003099">
        <property type="entry name" value="Prephen_DH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02153">
        <property type="entry name" value="PDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51176">
        <property type="entry name" value="PDH_ADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="domain" description="Prephenate/arogenate dehydrogenase" evidence="2">
        <location>
            <begin position="11"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="307" mass="32887" checksum="99A3057D8E546B85" modified="2018-07-18" version="1">MLAHTNTQQLTKVVIFGVGLIGGSFALALKKQAAVKQIVGVERNQNALERALGLGIIDVAGADLAAALDGADLVLIAAPVAQTEAILRAIYPHLQAQTIVTDAGSTKADVVEAARRALEDKISQFVPAHPIAGRESNGPDAAIANLYQGKKLVITALPENSPSALNLVANTWQRCGAVPYYLNPAEHDQVFAAVSHLPHLLAYALVDQITEQPQAELRFQYAASGFRDFTRIAGSSPEMWRDISLANRAALLVELTHYQAQLQRISNALQHSDGEQLLAIFSNAQAARQRWSQSIESAEPPPKEGGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZ50</accession>
    <name>A0A2S9GZ50_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">DNA gyrase subunit A</fullName>
            <ecNumber evidence="8">5.6.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">gyrA</name>
        <name evidence="11" type="ORF">S2091_2418</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>ATP-dependent breakage, passage and rejoining of double-stranded DNA.</text>
            <dbReference type="EC" id="5.6.2.2"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="8">Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="8">Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the topoisomerase GyrA/ParC subunit family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the type II topoisomerase GyrA/ParC subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.2" evidence="8"/>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC93001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93001">
        <property type="protein sequence ID" value="PRC93001"/>
        <property type="gene ID" value="S2091_2418"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034335">
        <property type="term" value="F:DNA negative supercoiling activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006265">
        <property type="term" value="P:DNA topological change"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006261">
        <property type="term" value="P:DNA-templated DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00187">
        <property type="entry name" value="TOP4c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.268.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.199.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01897">
        <property type="entry name" value="GyrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005743">
        <property type="entry name" value="GyrA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006691">
        <property type="entry name" value="GyrA/parC_rep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035516">
        <property type="entry name" value="Gyrase/topoIV_suA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013760">
        <property type="entry name" value="Topo_IIA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013758">
        <property type="entry name" value="Topo_IIA_A/C_ab"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013757">
        <property type="entry name" value="Topo_IIA_A_a_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002205">
        <property type="entry name" value="Topo_IIA_dom_A"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03989">
        <property type="entry name" value="DNA_gyraseA_C"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00521">
        <property type="entry name" value="DNA_topoisoIV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00434">
        <property type="entry name" value="TOP4c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101904">
        <property type="entry name" value="SSF101904"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56719">
        <property type="entry name" value="SSF56719"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7 8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0799">Topoisomerase</keyword>
    <feature type="domain" description="TOP4c" evidence="10">
        <location>
            <begin position="11"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="867"/>
            <end position="897"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GyrA-box" evidence="8">
        <location>
            <begin position="571"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="881"/>
            <end position="897"/>
        </location>
    </feature>
    <feature type="active site" description="O-(5'-phospho-DNA)-tyrosine intermediate" evidence="8">
        <location>
            <position position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC93001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="897" mass="99648" checksum="F017FB28D8CC1CDC" modified="2018-07-18" version="1">MDQFAKETLPISLEEEMRKSYLDYAMSVIVGRALPDVRDGLKPVHRRVLFAMHEMNNVYNRPFVKCARVVGEVMGKYHPHGDASIYDTLVRMAQHFSLRYTLVDGQGNFGSVDGDNAAAMRYTECRLSKIANEILADIDKETVDFVPNYDGKEKEPSVLPTRIPNLLINGASGIAVGMATNIPPHNITEVITGALHLLSNPQCTIDELIEIIPAPDFPTAGIIYGVSGVRDGYRTGRGRVVMRAKTHYEEYGKEGRTALIVDELPYQVNKKSLLERIAELVRDKKLDGISDIRDESDKSGMRVVIELKRNEVPEVVLNNLYKQTQLQDTFGMNMVALVNGQPKLLNLKQMLDCFLSHRREVVTRRTVFELKKARERGHMLEGLAVALANIDDFIAIIKAAPTPPMAKSELMSRAWDSSMVREMLTRTSADNVGGIDAFRPANLPKHYGIQTDGLYKLSDDQAQEILQMRLQRLTGLEQDKIVNEYKEMMIQIADLLDILSKPSRVTTIITDELTAAMNEYGVGNKDVRRSEIVHNATELETEDLITPQDMVVTLSHTGYMKSQPVSEYRAQKRGGRGKQAMATKDDDWIEQLFTANTHDYILCFSNRGRLYWLKVWEVPQGSRNSRGKPIVNMFPLHDGEKITVILPISGDNRTFPEDRYIFMSTSLGVVKKSALSDFSNPRKAGIIAVDLDEGDVLIGAALTDGKHDVMLFSDSGKAVRFDEGDVRPMGRTARGVRGMNLEEGQQVIALLVAENEQQSVLTATENGFGKRTPIGEYTRHGRGTKGMIAIQTSERNGKVVAATLVDTTDEILLITTGGVLIRTRVAEIREMGRATQGVTLIAVEDGTKLSGLQRIVETDVEEVIYENGENPDAVADVSTDASTDDGKDEAAPEDTAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZ77</accession>
    <name>A0A2S9GZ77_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Acyl-coenzyme A dehydrogenase</fullName>
            <ecNumber evidence="6">1.3.8.7</ecNumber>
            <ecNumber evidence="7">1.3.8.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">S2091_2427</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>a long-chain 2,3-saturated fatty acyl-CoA + H(+) + oxidized [electron-transfer flavoprotein] = a long-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein]</text>
            <dbReference type="Rhea" id="RHEA:17721"/>
            <dbReference type="Rhea" id="RHEA-COMP:10685"/>
            <dbReference type="Rhea" id="RHEA-COMP:10686"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58307"/>
            <dbReference type="ChEBI" id="CHEBI:83721"/>
            <dbReference type="ChEBI" id="CHEBI:83727"/>
            <dbReference type="EC" id="1.3.8.8"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a medium-chain 2,3-saturated fatty acyl-CoA + H(+) + oxidized [electron-transfer flavoprotein] = a medium-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein]</text>
            <dbReference type="Rhea" id="RHEA:14477"/>
            <dbReference type="Rhea" id="RHEA-COMP:10685"/>
            <dbReference type="Rhea" id="RHEA-COMP:10686"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58307"/>
            <dbReference type="ChEBI" id="CHEBI:83723"/>
            <dbReference type="ChEBI" id="CHEBI:83726"/>
            <dbReference type="EC" id="1.3.8.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Lipid metabolism; fatty acid beta-oxidation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.8.7" evidence="6"/>
    <dbReference type="EC" id="1.3.8.8" evidence="7"/>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC93010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93010">
        <property type="protein sequence ID" value="PRC93010"/>
        <property type="gene ID" value="S2091_2427"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00659"/>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004466">
        <property type="term" value="F:long-chain-acyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033539">
        <property type="term" value="P:fatty acid beta-oxidation using acyl-CoA dehydrogenase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015396">
        <property type="entry name" value="DUF1974"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09317">
        <property type="entry name" value="DUF1974"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="SSF47203"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="SSF56645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0274">FAD</keyword>
    <keyword evidence="9" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="42"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_N" evidence="14">
        <location>
            <begin position="130"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_M" evidence="13">
        <location>
            <begin position="240"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_1" evidence="12">
        <location>
            <begin position="363"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1974" evidence="15">
        <location>
            <begin position="517"/>
            <end position="807"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00012040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00020144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF09317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="PRC93010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="830" mass="91015" checksum="8697E13209BA053E" modified="2018-07-18" version="1">MALWILVAILATLGLIYAEIAGRYRVAAILLWIGVGYFSATIGFETGVVLLLCIALPAVIIAAPALRRSLISPSILDLFKRILPAMSDTERDALEAGSIWWDAELFSGNPNWSKLLSFPAPSLTSIEQSFLDHEVNELCGLIKDWDTTQVWQDLPPEAWKYIKENGFLGMIIPRKYGGKEFSAYMHSQVIMKLSTHCSALAVSVMVPNSLGPAELLLHYGTTTQKDYYLPRLASGLEIPCFALTNPYAGSDAASIPDVGVVCRVEIKGTLVLGLRVSWSKRYITLAPIATLLGLAFRTLDPDHLLGDSTDLGITCALVPTSHQGVVIGRRHWPLNAVFQNGPTSGTDVFIPMDWVIGGLPQIGKGWRMLMECLAAGRAISLPSSNVGMAKLAVRGTSAYAAIRRQFNTAIGQFEGVQEALARMGGNLYLMDAARQLSVVGLDLGEKPAVISAIVKYHVTERARMVVNDGMDILGGKGICMGPNNFLARAYQQVPIAITVEGANILTRCLIIFGQGAIRSHPFVLKEMHATHEPNRRKAIDDFDRAFFGHVGFFLNNLVRSIVIGLSAGYAASVPKSAAPELHRYYRAVSHLSSAFALLTDLSMFVLGKSLKRRERISGRLGDILSQMYLISAVLKRFEDDGRPEEDAPYVHWSIQDALQRAQQALIGVLDNFPNRLSALLMRIVIFPLGLPHRAPLDALGTKVAVAMQAPGESRDRLLADSFIQGEYGDIISNCEMAFRLLPKFEAIEKRLKTAIHAGALTPIPQNLAVMHDWVLHASLVGTINIEERRLMLDFTRFTNIAVQVNDFPQDFNIVNDAEKRHGLESSALTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZA2</accession>
    <name>A0A2S9GZA2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Sortase and related acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2373</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92956">
        <property type="protein sequence ID" value="PRC92956"/>
        <property type="gene ID" value="S2091_2373"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="8"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="169" mass="18845" checksum="9E97DB2949977E1F" modified="2018-07-18" version="1">MSPNASDILVRSVTIADAGALCVIYNHYVLHSTISFEEEPISEDEMAQRIVGVTVSFPWLVAELNGRILGYAYASKWRVRHAYRFAVESSIYLGSDVAAKGIGSLLYLELINALKEQNVHTVIAGIALPNLASISLHKKFGFEPVAQFKEVGFKKNAWIDVMYWQLLLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZD8</accession>
    <name>A0A2S9GZD8_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HTH cro/C1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2156</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93070">
        <property type="protein sequence ID" value="PRC93070"/>
        <property type="gene ID" value="S2091_2156"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="20"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="122" mass="13572" checksum="0EE1B32E45F1C9AD" modified="2018-07-18" version="1">MKTYGDRLTESLRIAQKERQELADGIGVSVQAIGQVLAGKTKALTAENSAYAAKFLNVDAFWLATGHGSSTTKVNEATWPFKIRLEAFLALPLDERQRIEDYLEFSVNKWHATQDVKSLKAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZL5</accession>
    <name>A0A2S9GZL5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative signal transduction protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2265</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93179">
        <property type="protein sequence ID" value="PRC93179"/>
        <property type="gene ID" value="S2091_2265"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013976">
        <property type="entry name" value="HDOD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08668">
        <property type="entry name" value="HDOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51833">
        <property type="entry name" value="HDOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HDOD" evidence="1">
        <location>
            <begin position="21"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="278" mass="29745" checksum="67FE43B2F95C1236" modified="2018-07-18" version="1">MDRLEAFRSIAAQASRGEITLSTNINATLKVKQMLDDPDAHLAGATKLVLADPLFSARTVSIANSAAYNRSGTKINNVTTAVMRLGFGTLRSLAASLIVRQMNNGLTNPIIKQKSAELWEHTACVAALAQVIARRMTRVDPDAALFAGIVHEVGGFYLLSRAEEFPGLLDGELEGWVEYGEKIIGRGVLKALDIPETICEAIEQVWNGVGAQPPVTLGDVLILANDLATTLSPLQPASEVAIHDADTKVDFNVGDETLSSILDDATEQIESLREALLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZX2</accession>
    <name>A0A2S9GZX2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1988</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93250">
        <property type="protein sequence ID" value="PRC93250"/>
        <property type="gene ID" value="S2091_1988"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015562">
        <property type="term" value="F:efflux transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003423">
        <property type="entry name" value="OMP_efflux"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010131">
        <property type="entry name" value="RND_efflux_OM_lipoprot_NodT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02321">
        <property type="entry name" value="OEP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01845">
        <property type="entry name" value="outer_NodT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0564">Palmitate</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1134">Transmembrane beta strand</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015373278" evidence="2">
        <location>
            <begin position="20"/>
            <end position="480"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU362097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="480" mass="52109" checksum="DD63AD64809C3692" modified="2018-07-18" version="1">MKPLRYGMMLYALACAACSLEPVYQTPVMPVPVAYKGATELWQRAQPSDTLSRGDWWLRYDDPTLNQLISRLDAANIDLTIAVAHFEEANAYAEQAHAGLFPTITAGAYTTRNRQSDTRALRSSTQPDDYGDNALGMTLGYELDLWGRVRSLAKAGQAGAQAAAADMESIRLSLRAELADDYLALRILDNKAKLLADEVESYSNAVTLTQNRFLGEIDSALNVSRAKAQLATTQERLSENSAERALYEHAIATLIGESASTYSIAPVVMELHLPDIPLELPATILQRRPDIAAAERRLAEANAQIGVTKAAFYPTINLAATGGYESTYQPGLLSAPNLFWSIGPNALLTLFDAGRRTAVVAQAQAAFDAAGGQYRLTVLRAFQEVEDNLSLLNELYKESVALNDAVLETNHSLNLAMNLYRAGAVSYLDVVSAQTLAQQAEFDALNVQKRRLQASIGLIRALGGGWSSSQKNDSQNSASK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZY3</accession>
    <name>A0A2S9GZY3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cro/C1-type HTH DNA-binding domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2032</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93294">
        <property type="protein sequence ID" value="PRC93294"/>
        <property type="gene ID" value="S2091_2032"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13443">
        <property type="entry name" value="HTH_26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="27"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00530"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="272" mass="31704" checksum="EEF8644C6EE0A3F4" modified="2018-07-18" version="1">MTMPVVSSFATLQTFDAMSKAITIIDALKRELKNRDITYADLAERIRMSEASVKRMFSQKNFTLQRLDEILLAAEIDFHDLTSHEHESKLILELSYEQEQEIISDPKKFLVAVSALNLLTLEQIVDIYAMTEAEVVGYLLRLDKIGFLELQPNNRIKLLVARTFKWISNGPIQHYFKAQAYADYLNSDFDGQHEIMRLVNVMLSRPSIDQLLTRLKQVAREFSEQHQTDAKLPLTDKHRISFMLAARPWLPDEFKKLVRKEWLEKNSKEMAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZY4</accession>
    <name>A0A2S9GZY4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Polyphosphate kinase 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_2015</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93277">
        <property type="protein sequence ID" value="PRC93277"/>
        <property type="gene ID" value="S2091_2015"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008976">
        <property type="term" value="F:polyphosphate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016898">
        <property type="entry name" value="Polyphosphate_phosphotransfera"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022488">
        <property type="entry name" value="PPK2-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022486">
        <property type="entry name" value="PPK2_PA0141"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03976">
        <property type="entry name" value="PPK2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028756">
        <property type="entry name" value="PPK2_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03707">
        <property type="entry name" value="PPK2_P_aer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PPK2" evidence="4">
        <location>
            <begin position="53"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC93277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="306" mass="36365" checksum="91BFD6F71D8819AC" modified="2018-07-18" version="1">MRLNNEELLSRIHSELADSNDEELELELVDDRSLESFTDEGAPEPTAADKENRRLYFRELFRLQAELVKLQDWVVHTGHKVVILFEGRDAAGKGGVIKRITQRLNPRVCRVAALPAPNDREQTQWYFQRYVSHLPAAGEIVLFDRSWYNRAGVERVMNFCTDDQYEEFFRTVPEFERMLVRSGIQVIKYWFSISDEEQHARFLGRIYDPLKQWKLSPMDLESRRRWEEYTKAKEIMLERTNIAEAPWWLVQANDKKKARLNCIHHLLAQMPYEEITHQAITLPQRERHEDYERLPMSSDIIVPEVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H040</accession>
    <name>A0A2S9H040_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">P pilus assembly protein pilin FimA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2090</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93352">
        <property type="protein sequence ID" value="PRC93352"/>
        <property type="gene ID" value="S2091_2090"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009289">
        <property type="term" value="C:pilus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007155">
        <property type="term" value="P:cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1090">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036937">
        <property type="entry name" value="Adhesion_dom_fimbrial_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008966">
        <property type="entry name" value="Adhesion_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039458">
        <property type="entry name" value="FimA-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16970">
        <property type="entry name" value="FimA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49401">
        <property type="entry name" value="SSF49401"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015400132" evidence="1">
        <location>
            <begin position="25"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="177" mass="17506" checksum="F9A130901213C974" modified="2018-07-18" version="1">MKVKILLSAVIATLGFAGLNAAQASDGTVNFTGTVVATTCTVAPASVTQTVALPQVSVTALTGAGTTAGATAFNIGLAACTAGSKARIQFEAGPNVDPVTGNLKITSAAPATNVQIQLVNQAGGAINMATNVNQVTANDATLTAGVNTFYYTAQYISSATAVAGSANTSVTWSIAYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H045</accession>
    <name>A0A2S9H045_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Response regulator receiver domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2097</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93359">
        <property type="protein sequence ID" value="PRC93359"/>
        <property type="gene ID" value="S2091_2097"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="3"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="176" mass="20092" checksum="C0AA119A9D85F613" modified="2018-07-18" version="1">MKRIMLVDDEENVLHSLQRALRKIGNEQQLLFELHTSPIDAIKRLGEAQFNLVISDYHMPAMSGVDFLKLAKAIQPETIRLMLSASADFKTLLDAINEAEVFRYIEKPWNVSDLEEVVRLALLQYGNALAERLLLNESKLQKNEITPQEFEAKKLEMEEPGITKVKWGTDGSVLLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0A2</accession>
    <name>A0A2S9H0A2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transglycosylase SLT domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_1770</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the transglycosylase Slt family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93383">
        <property type="protein sequence ID" value="PRC93383"/>
        <property type="gene ID" value="S2091_1770"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008933">
        <property type="term" value="F:lytic transglycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000270">
        <property type="term" value="P:peptidoglycan metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00118">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.350.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036779">
        <property type="entry name" value="LysM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023346">
        <property type="entry name" value="Lysozyme-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000189">
        <property type="entry name" value="Transglyc_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008258">
        <property type="entry name" value="Transglycosylase_SLT_dom_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01476">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01464">
        <property type="entry name" value="SLT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00257">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53955">
        <property type="entry name" value="SSF53955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54106">
        <property type="entry name" value="SSF54106"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51782">
        <property type="entry name" value="LYSM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00922">
        <property type="entry name" value="TRANSGLYCOSYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015658774" evidence="2">
        <location>
            <begin position="24"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="3">
        <location>
            <begin position="339"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="3">
        <location>
            <begin position="414"/>
            <end position="457"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC93383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="502" mass="56092" checksum="0DBE2DFC44AA9771" modified="2018-07-18" version="1">MPPFRLKPLFLTTLMSLSGLSYAEPVLVASNTVTKEISIPEAIPAATNLHSLAFKPDDSPEIQEADLWNRIRQGYGIPNLDNSLVTSQLNWYSARTDYILRTTERASRYLYHVVEELEKRGMPTELALLPFIESAFNPQAMSTAKASGMWQFIPSTGRDFNLKQNMFKDERRGVLDSTDAALNYLQKLYDMFGDWQLALAAYNWGEGSVQRAIKKQQAAGLPIDFDSMSYLMPKETQNYVPKLQAVKNIISNPEFFNIALPKVDNQPYFASVDKTRDIDVRVAAQLAELTVAEFKQLNPQFNRPVITGNADTKILLPADNVEIYKYNLSKWEGPLSSWTAYTVGKNERIESIARRVGAQASVLKDVNQVPSNMMVKAGSTLLIPKSSQSADNDISQRVVDNASLTMTHDNTRKINVTASKKDSLTALAKRYKVSTAQIKEWNNLKSDTLKTGQKLQIEVAAAPSRRKNTRVAAISTPKKAIAVNKQTKKITVAQNKTHKQPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0H0</accession>
    <name>A0A2S9H0H0_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DsbD_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1871</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93484">
        <property type="protein sequence ID" value="PRC93484"/>
        <property type="gene ID" value="S2091_1871"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039447">
        <property type="entry name" value="UreH-like_TM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13386">
        <property type="entry name" value="DsbD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="72"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="101"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="154"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="186"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="218"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="domain" description="DsbD_2" evidence="2">
        <location>
            <begin position="9"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="261" mass="27568" checksum="906ADEA6E5B8456D" modified="2018-07-18" version="1">MNGLSLLPVFMIGLLGSVHCVGMCGGIVSAISVVSKSVLRIPVPVMIVADRRVGAGVLDVLVRTMSYNLGRIGSYAVAGAIAGGVAQSVRMLAGFTRIQMGGYWLVSLMLMALGLYLMGLLPRFAYLEFAGRGIWRRIQPLTKKLLPFDSPLKLFAAGVVWGWLPCGMVYSMLLTAMLSGSALSGAAVMLVFGVGTMPTLMTMGLLGAKLKTWMQRTPVRVAGGLIVLSFGLLGVIRAAHGMPMSWLDAFCVTPIAAEGGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0J0</accession>
    <name>A0A2S9H0J0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cupin domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1891</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93504">
        <property type="protein sequence ID" value="PRC93504"/>
        <property type="gene ID" value="S2091_1891"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013096">
        <property type="entry name" value="Cupin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07883">
        <property type="entry name" value="Cupin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cupin_2" evidence="1">
        <location>
            <begin position="55"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="126" mass="14047" checksum="C6BD5C0D0A3E6612" modified="2018-07-18" version="1">MSLNPQLTYVHLAENGAATQLPGGEEFWNMPEAEMERYGSGWLVSEFEFSVDWPTWEMHPNADEFVYLLSGSVEVHLEQQDGLRKVTLNGSGAVVVPRGIWHTVKVIAPSRMLHVTRGAGTQLRPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0L3</accession>
    <name>A0A2S9H0L3_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Mannose-1-phosphate guanylyltransferase</fullName>
            <ecNumber evidence="3">2.7.7.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_1906</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>alpha-D-mannose 1-phosphate + GTP + H(+) = diphosphate + GDP-alpha-D-mannose</text>
            <dbReference type="Rhea" id="RHEA:15229"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:57527"/>
            <dbReference type="ChEBI" id="CHEBI:58409"/>
            <dbReference type="EC" id="2.7.7.13"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the mannose-6-phosphate isomerase type 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.13" evidence="3"/>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93519">
        <property type="protein sequence ID" value="PRC93519"/>
        <property type="gene ID" value="S2091_1906"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004475">
        <property type="term" value="F:mannose-1-phosphate guanylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000271">
        <property type="term" value="P:polysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006375">
        <property type="entry name" value="Man1P_GuaTrfase/Man6P_Isoase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001538">
        <property type="entry name" value="Man6P_isomerase-2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005835">
        <property type="entry name" value="NTP_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01050">
        <property type="entry name" value="MannoseP_isomer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00483">
        <property type="entry name" value="NTP_transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01479">
        <property type="entry name" value="GMP_PMI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5 9" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NTP_transferase" evidence="7">
        <location>
            <begin position="6"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="domain" description="MannoseP_isomer" evidence="8">
        <location>
            <begin position="325"/>
            <end position="475"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC93519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="481" mass="52783" checksum="4D7ACE50E4CCCEF7" modified="2018-07-18" version="1">MNTVTPVILCGGSGTRLWPLSRAGFPKQFLVLSGTNSLFQQAISRINSIACTDILLADTLVVTNEEHRFLALEQLREMKSIKATLLLEPVGRNTAPALTFAALHAMANGSDPILAVIPADQTITDDGAYIKALQQCVRIAAEGAIAILGITPDRPETGFGYINFEGELGRNGEYTVTQFTEKPDLKTAQQFLESGDYTWNSGIFVLKASTWLAAIKHFRPDIETATQQAWLGKSEDFAFIRPGKAAFEQIPSASIDYAVMEKCPGSEVAIHMVPLSAGWNDLGAWSAVWMVGEQDANGNVVHGDVLHSDTSNSLIYSSKRLVSAVGVNNLVIVETADAVLVADRAQSQQVKKIVDALEKQNRLEHNTHRKVNRPWGWYDSIVEGERFKVKQIQVKPGAKISLQKHHHRAEHWVVVRGTAEITCGDKVTLLTENQSTYIPLGEVHRLSNPGSIPLEIIEVQSGSYLGEDDIVRYEDNYGRVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0S1</accession>
    <name>A0A2S9H0S1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1559</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93558">
        <property type="protein sequence ID" value="PRC93558"/>
        <property type="gene ID" value="S2091_1559"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003346">
        <property type="entry name" value="Transposase_20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002525">
        <property type="entry name" value="Transposase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01548">
        <property type="entry name" value="DEDD_Tnp_IS110"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02371">
        <property type="entry name" value="Transposase_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DEDD_Tnp_IS110" evidence="2">
        <location>
            <begin position="7"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="180"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="342" mass="38283" checksum="77F42EF07D060A84" modified="2018-07-18" version="1">MKITTFGIDLAKNVFQVHGVNDQGKAVLRKALRRDQVLEFFIKLSPCLVGMEACASAHYWARKLQSQGHTVKLMAPQYVKPYVKTNKNDAADAEAICEAVGRPNMRFVPIKNVEQQSVLSLHRARQGFVKSRTAQANQIRDLLSEYCIVIRQGICNVTKRLPHILEECANELPGVFCQLIQRLGDHLKELDRQVGELEVQIKIWHKQNEASKKLEEIPGVGPITATAIVASIGDAKCFKDGRQLAAWLGLVPRQHSSGGKQMLLGISKRGDSYLRTLLIHGARSVLRAAERKVHHAGSWLANLMERRNFNVAVVALANKNARIIWALLAHERKYQINFASGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0T7</accession>
    <name>A0A2S9H0T7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ogt: methylated-DNA-[protein]-cysteine S-methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1592</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93591">
        <property type="protein sequence ID" value="PRC93591"/>
        <property type="gene ID" value="S2091_1592"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003908">
        <property type="term" value="F:methylated-DNA-[protein]-cysteine S-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06445">
        <property type="entry name" value="ATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014048">
        <property type="entry name" value="MethylDNA_cys_MeTrfase_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036217">
        <property type="entry name" value="MethylDNA_cys_MeTrfase_DNAb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036631">
        <property type="entry name" value="MGMT_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01035">
        <property type="entry name" value="DNA_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46767">
        <property type="entry name" value="SSF46767"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53155">
        <property type="entry name" value="SSF53155"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00589">
        <property type="entry name" value="ogt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DNA_binding_1" evidence="1">
        <location>
            <begin position="76"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="162" mass="17731" checksum="74B98D5BAB57DC6E" modified="2018-07-18" version="1">MNKDTWFCAVIPAPFGAVGIRTEAGLLRELEYLPASHALQEPATALTQEVTHQIQCYFENPAFQFTVPLAPIGTEHQRKVWQAISQIPLGQVINYGQIAKQIASAPRAVGQACGANWYPIIIPCHRVTAAKGLGGFAHHSEVAGFHLTVKRWLLAHEGVHGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0W8</accession>
    <name>A0A2S9H0W8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Response regulator of the LytR/AlgR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_1893</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93506">
        <property type="protein sequence ID" value="PRC93506"/>
        <property type="gene ID" value="S2091_1893"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007492">
        <property type="entry name" value="LytTR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04397">
        <property type="entry name" value="LytTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00850">
        <property type="entry name" value="LytTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50930">
        <property type="entry name" value="HTH_LYTTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="4"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="HTH LytTR-type" evidence="3">
        <location>
            <begin position="147"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC93506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="249" mass="28673" checksum="E9F861F29910D641" modified="2018-07-18" version="1">MTINALIVDDEPLARQRIRQMIADEPGFNVAGEAGNGLEALTQIESLHPDLVFLDIQMPELDGFGVIEAIGVERMPPTLFVTAYDAHALRAFEFHAMDYLLKPFDRERFSQALKWVREHPQALCRDQGGFKSLMETMDTVRSRTDRFLVKSGERWVVLQTKHIRWIVAEENYVRIQLDGTSHLIRQTMSGILARLDPLCFKRIHRSSIVNLDFVQELHPWTGGDLVVVMQDGTRLTLSRTYRHQFTELK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0X5</accession>
    <name>A0A2S9H0X5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Sigma70-ECF: RNA polymerase sigma factor, sigma-70 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_1601</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93600">
        <property type="protein sequence ID" value="PRC93600"/>
        <property type="gene ID" value="S2091_1601"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="2">
        <location>
            <begin position="24"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="3">
        <location>
            <begin position="126"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC93600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="191" mass="21955" checksum="1EAD41ABDE864649" modified="2018-07-18" version="1">METTLNPNQSMATQDKHISDTVLREQARLGNFIRQRVADQSEAEDILQDVFYELVEAYRLPEPIEQVGAWLFRVARNRIIDRFRKKREQPLPETEADSGDEYWLEQVLPASDAGPEAAYARAVLLEELHDALDELPLEQREVFIAHELEGLSFKELAALSGVGVNTLLARKRYAVLHLRTHLQAIYNEFNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1E8</accession>
    <name>A0A2S9H1E8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="8">SoxR: redox-sensitive transcriptional activator SoxR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_1424</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93815">
        <property type="protein sequence ID" value="PRC93815"/>
        <property type="gene ID" value="S2091_1424"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01110">
        <property type="entry name" value="HTH_SoxR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000551">
        <property type="entry name" value="MerR-type_HTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010211">
        <property type="entry name" value="Redox-sen_tscrpt-act_SoxR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015358">
        <property type="entry name" value="Tscrpt_reg_MerR_DNA-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30204:SF0">
        <property type="entry name" value="PTHR30204:SF0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00376">
        <property type="entry name" value="MerR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09278">
        <property type="entry name" value="MerR-DNA-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00422">
        <property type="entry name" value="HTH_MERR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01950">
        <property type="entry name" value="SoxR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00552">
        <property type="entry name" value="HTH_MERR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50937">
        <property type="entry name" value="HTH_MERR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH merR-type" evidence="7">
        <location>
            <begin position="24"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC93815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="187" mass="20831" checksum="56040CF6C9464464" modified="2018-07-18" version="1">MEVKKKAEMSTEMSTERAAEITTLISIGELARRSGVASSALRFYEERGLIQSIRPVALESGKPRSSRRMYAKDVLRRVSFIRVAQIVGLSLDEIQQALATLPQQRTPGKQDWERLSRSWQPLIQERIDTLTKLRDQLSSCIGCGCLSLKSCALYNPGDLAGLRGSGARYLMGDSSKTVLAENRIKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1H0</accession>
    <name>A0A2S9H1H0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1440</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93831">
        <property type="protein sequence ID" value="PRC93831"/>
        <property type="gene ID" value="S2091_1440"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016980">
        <property type="entry name" value="S-AdoMet-dep_MeTrfase_Alr7345"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF031679">
        <property type="entry name" value="Mtase_Alr7345_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015516371" evidence="1">
        <location>
            <begin position="29"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="274" mass="30280" checksum="C2F24D14084A0C15" modified="2018-07-18" version="1">MKRFPSMRLLPTLLTALLCLGFSQTVLADEALQTAIDGAHRSDVNKSRDAARHPKEVLQFFGITPTMTVVELMPGAGWYTEILAPYLKPQGQLIEALQDPVSESEYGRNSYAKFQKKLNDNPAVFDKVKTAIFEPPVKLNFAPNNSVDMVLTFRNIHNWAISGDENMKQLFKHVYSSLKTGGVFGVVDHRLPAGKVQDANASTGYVSEAYVIKLAESVGFKLVAKSEINANPKDTADHKGGVWALPPTYANKDADRQSYADIGESDRMTLKFVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1M3</accession>
    <name>A0A2S9H1M3_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 2">Peptidyl-tRNA hydrolase</fullName>
            <shortName evidence="1">PTH</shortName>
            <ecNumber evidence="1 2">3.1.1.29</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">pth</name>
        <name evidence="4" type="ORF">S2091_1375</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 2">
            <text>an N-acyl-L-alpha-aminoacyl-tRNA + H2O = a tRNA + an N-acyl-L-amino acid + H(+)</text>
            <dbReference type="Rhea" id="RHEA:54448"/>
            <dbReference type="Rhea" id="RHEA-COMP:10123"/>
            <dbReference type="Rhea" id="RHEA-COMP:13883"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:59874"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:138191"/>
            <dbReference type="EC" id="3.1.1.29"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the PTH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.29" evidence="1 2"/>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93766">
        <property type="protein sequence ID" value="PRC93766"/>
        <property type="gene ID" value="S2091_1375"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004045">
        <property type="term" value="F:aminoacyl-tRNA hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00462">
        <property type="entry name" value="PTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1470">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00083">
        <property type="entry name" value="Pept_tRNA_hydro_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001328">
        <property type="entry name" value="Pept_tRNA_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018171">
        <property type="entry name" value="Pept_tRNA_hydro_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036416">
        <property type="entry name" value="Pept_tRNA_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17224">
        <property type="entry name" value="PTHR17224"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01195">
        <property type="entry name" value="Pept_tRNA_hydro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53178">
        <property type="entry name" value="SSF53178"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00447">
        <property type="entry name" value="pth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01195">
        <property type="entry name" value="PEPT_TRNA_HYDROL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01196">
        <property type="entry name" value="PEPT_TRNA_HYDROL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC93766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="194" mass="21469" checksum="EF8CD43EFA15CFD2" modified="2018-07-18" version="1">MSIRLIVGLGNPGPEYQLTRHNAGFWLVDNLANSLPHCALQRDTRMNALMAKTNIAGQETWLLEPQTYMNRSGQSVGALARFYKIAPDEILVVHDELDIDPGVAKLKKGGSSGGHNGLKDITAALGTQDYWRLRIGIGHPRSLNSQQAVVDFVLHRPRKEEQILIDETIEKSLQIIPLLVAGKFDAATMQLHTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H232</accession>
    <name>A0A2S9H232_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cytotoxic translational repressor of toxin-antitoxin stability system</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1218</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94045">
        <property type="protein sequence ID" value="PRC94045"/>
        <property type="gene ID" value="S2091_1218"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2310.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007712">
        <property type="entry name" value="RelE/ParE_toxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035093">
        <property type="entry name" value="RelE/ParE_toxin_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05016">
        <property type="entry name" value="ParE_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143011">
        <property type="entry name" value="SSF143011"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-1277">Toxin-antitoxin system</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="84" mass="9766" checksum="F584447FD8DFB8A0" modified="2018-07-18" version="1">MNSVNYTPKAAKQLRKLQAQDSKKVRGECDKLAAMPNCINVKSLTNHEYQYRLRVGGYRVFFNFDGVIHIVSIQEVKKRDENTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H260</accession>
    <name>A0A2S9H260_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Sensor protein</fullName>
            <ecNumber evidence="5">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_1248</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Member of a two-component regulatory system.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="5"/>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94075">
        <property type="protein sequence ID" value="PRC94075"/>
        <property type="gene ID" value="S2091_1248"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006290">
        <property type="entry name" value="CztS_silS_copS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01386">
        <property type="entry name" value="cztS_silS_copS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5 8" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0902">Two-component regulatory system</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="173"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="7">
        <location>
            <begin position="202"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="6">
        <location>
            <begin position="254"/>
            <end position="467"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU364088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC94075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="471" mass="52498" checksum="58E9541560F9FB48" modified="2018-07-18" version="1">MKNQRHSLLTRLALLFAALSFVLLATIGYTLYAALVAQLVKRDDAALVTRVDQIRTLLRDEDILNLIKEKPELFANMLGNREALLILKFPGQQPLIEVNPGHIAVPEIPPMPVGTVLDLSSVRHSVENGTPFIVVSTTVQIIDQHRNVHDLQITSGRLLTERTHMLMTYRQQIVEVALIAALLTAALAYWIAYHSLIPIRWLAAQTGAIGIGNLSTRIDSSMAPRELLPLIEGFNAMLNRLETSFAQLSQVSADMAHDLRTPIGNLMGQTEVALSQKRSTEYYEKLLGSNFEELQRVSKMTDNMLFLARAEHADHAIERKQLDVANELERMVDYFEGLADERNLKLEWHGAGLVWADANLLRRALANLLSNAVRYADEGTTISLLVKQEPAGTSMIVENSGPTIEAHHIARLFDRFYRADASRRGSSDASGLGLSIVRSIMLLHQGTWDVTSSAGISCFTLFFPKQSNQYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H276</accession>
    <name>A0A2S9H276_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">UPF0060 membrane protein S2091_1264</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_1264</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the UPF0060 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94091">
        <property type="protein sequence ID" value="PRC94091"/>
        <property type="gene ID" value="S2091_1264"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00010">
        <property type="entry name" value="UPF0060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003844">
        <property type="entry name" value="UPF0060"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36116">
        <property type="entry name" value="PTHR36116"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02694">
        <property type="entry name" value="UPF0060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="7"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="63"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="86"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC94091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="110" mass="11902" checksum="302BFA08F9FADE76" modified="2018-07-18" version="1">MLQLIKLTALFAITALAEIIGCYLPWLVLKQGKPIWLLLPAALSLALFAWLLTLHPSAAGRTYAAYGGMYIAIALLWLRFVDGITLSRWDMVGAGMALAGMAVIVMQPKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2I6</accession>
    <name>A0A2S9H2I6_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Endoribonuclease YbeY</fullName>
            <ecNumber evidence="7">3.1.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ybeY</name>
        <name evidence="8" type="ORF">S2091_0810</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="7">Binds 1 zinc ion.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the endoribonuclease YbeY family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="7"/>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94189">
        <property type="protein sequence ID" value="PRC94189"/>
        <property type="gene ID" value="S2091_0810"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004521">
        <property type="term" value="F:endoribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00009">
        <property type="entry name" value="Endoribonucl_YbeY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023091">
        <property type="entry name" value="MetalPrtase_cat_dom_sf_prd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002036">
        <property type="entry name" value="YbeY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020549">
        <property type="entry name" value="YbeY_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02130">
        <property type="entry name" value="YbeY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00043">
        <property type="entry name" value="TIGR00043"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01306">
        <property type="entry name" value="UPF0054"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 7" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="5 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 7" id="KW-0540">Nuclease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="7" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="6 7" id="KW-0862">Zinc</keyword>
    <feature type="binding site" evidence="7">
        <location>
            <position position="113"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="117"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="123"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC94189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="154" mass="17202" checksum="AE9C601EB2819E91" modified="2018-07-18" version="1">MAEKFKLKLTLQFPDKRLQKQLTKALLKSAVQAALFAPAELTLRFVDAVEGKTLNREYRGKDYATNVLTFAYTEDMDAETTQADIILCTDVLQQEASAQHKSITDHALHLIVHGVLHAQGYDHEDEEEAVEMEGLEAEILATLGVDNPYAGEDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2R3</accession>
    <name>A0A2S9H2R3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">MarR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0871</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94250">
        <property type="protein sequence ID" value="PRC94250"/>
        <property type="gene ID" value="S2091_0871"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01047">
        <property type="entry name" value="MarR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00347">
        <property type="entry name" value="HTH_MARR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50995">
        <property type="entry name" value="HTH_MARR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="1">
        <location>
            <begin position="15"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="151" mass="17145" checksum="CC961950D95A701B" modified="2018-07-18" version="1">METKSHKINQVPQLDGQLCFALYSTSLAMSKLYRKLLRKMGITYSQYLVLMVLWQRDELTVSDIGAHLYLDSATLTPLLKRMEALELITRERAANDERQVIISLTKTGNAMRKQAAELPNSVLCAIECMPEQAIDLKMRLEALRASLMKNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2S2</accession>
    <name>A0A2S9H2S2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Biopolymer transport protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_0881</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the ExbD/TolR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94260">
        <property type="protein sequence ID" value="PRC94260"/>
        <property type="gene ID" value="S2091_0881"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003400">
        <property type="entry name" value="ExbD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30558">
        <property type="entry name" value="PTHR30558"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02472">
        <property type="entry name" value="ExbD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC94260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="136" mass="14508" checksum="80D40F064C4BBD02" modified="2018-07-18" version="1">MAFSTGNNSAEVLSEINITPLVDVMLVLLVTFIITAPLLNNAVHINLPKTATTAPPNDIKPVTVSIDGSNHVFIDKREVNLTALEFELHELVAHNPDLSLSLQADEGVPYRSVAKVITNIQRAGISKLSVLTATGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2U8</accession>
    <name>A0A2S9H2U8_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF4124 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0925</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94304">
        <property type="protein sequence ID" value="PRC94304"/>
        <property type="gene ID" value="S2091_0925"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025392">
        <property type="entry name" value="DUF4124"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13511">
        <property type="entry name" value="DUF4124"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015672955" description="DUF4124 domain-containing protein" evidence="1">
        <location>
            <begin position="23"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4124" evidence="2">
        <location>
            <begin position="12"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="123" mass="12922" checksum="5067D35AFC898222" modified="2018-07-18" version="1">MQLKLSVQFAILFISLPLQVQAGVFKCTLPDGSTSFQDTPCPANAGQSTVTLHSASVDSAATPKNTSLPSKEEKAEVAKLFASCAHAMDHWNAVKAAKATRSGTANSDAELKAAEKRVADECN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2Z6</accession>
    <name>A0A2S9H2Z6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Taurine catabolism dioxygenase TauD, TfdA family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0972</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94351">
        <property type="protein sequence ID" value="PRC94351"/>
        <property type="gene ID" value="S2091_0972"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042098">
        <property type="entry name" value="TauD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003819">
        <property type="entry name" value="TauD/TfdA-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02668">
        <property type="entry name" value="TauD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TauD" evidence="2">
        <location>
            <begin position="22"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="322" mass="36528" checksum="893CCA0D00436506" modified="2018-07-18" version="1">MPSTSRAGSTVSPLIEPSNSREATLDYLLNYINSDRQKFRLELEQSGTLLFRNFQINTVEQFDRFTQTVLSSRVRYRGGDARRTLTTDYVYTSNDTSGEKYISVHNEMGYSRAHPEILIFYCKKADMIGGETLLTDGRKIAERLSPAAALAFALTEVTYIQNLPAQSNGAPEWPKTWAQTFESNNPDEVSRLLDKRGARFWWTPEMSLHIEETLPSVVAGAYTGVNALFCQADRWHASQHDDGTRQEILAINGSDRYHHCIFANGKEMNPDHLRELGKIKKELAIGHQWQSGDVLLIDNSMTLHGRTPYRGLRELFVAMGKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H341</accession>
    <name>A0A2S9H341_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Fido domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_1020</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94399">
        <property type="protein sequence ID" value="PRC94399"/>
        <property type="gene ID" value="S2091_1020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003812">
        <property type="entry name" value="Fido"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036597">
        <property type="entry name" value="Fido-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040198">
        <property type="entry name" value="Fido_containing"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13504">
        <property type="entry name" value="PTHR13504"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02661">
        <property type="entry name" value="Fic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140931">
        <property type="entry name" value="SSF140931"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51459">
        <property type="entry name" value="FIDO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fido" evidence="3">
        <location>
            <begin position="19"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="111"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="115"/>
            <end position="122"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="153"/>
            <end position="154"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR640198-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR640198-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC94399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="273" mass="30878" checksum="E25891F1FE6A2842" modified="2018-07-18" version="1">MDGIVEMVLDATTNYAKPLTQDRLFAWHAALFPTGYSNLSTIRTGCWRDDATGPMQVVSGAIGRQKIHFEAPPADKLNHEMNLFLDWFNQRPVIDPVLKAGLAHCWLVTLHPFDDGNGRIARAVGDMALARSEQLPQRFYSLSAQIHRERRDYYDLLERIQKGSLDVTAWLSWFLGCLQRAIDGAEITLSTVLEKSNFWRRWAGTPLNERQIKIINRMLDGFDGKLTSSKWAAIAKCSPDTALRDATELIQRGLMHKSDSGGRSTSYELILEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H383</accession>
    <name>A0A2S9H383_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Tyrosine recombinase XerC</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">xerC</name>
        <name evidence="13" type="ORF">S2091_1066</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the 'phage' integrase family. XerC subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94445">
        <property type="protein sequence ID" value="PRC94445"/>
        <property type="gene ID" value="S2091_1066"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009037">
        <property type="term" value="F:tyrosine-based site-specific recombinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01808">
        <property type="entry name" value="Recomb_XerC_XerD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044068">
        <property type="entry name" value="CB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002104">
        <property type="entry name" value="Integrase_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010998">
        <property type="entry name" value="Integrase_recombinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004107">
        <property type="entry name" value="Integrase_SAM-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023009">
        <property type="entry name" value="Tyrosine_recombinase_XerC/XerD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02899">
        <property type="entry name" value="Phage_int_SAM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00589">
        <property type="entry name" value="Phage_integrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51900">
        <property type="entry name" value="CB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51898">
        <property type="entry name" value="TYR_RECOMBINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3 9" id="KW-0132">Cell division</keyword>
    <keyword evidence="4 9" id="KW-0159">Chromosome partition</keyword>
    <keyword evidence="2 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 9" id="KW-0229">DNA integration</keyword>
    <keyword evidence="7 9" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="6 9 10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core-binding (CB)" evidence="12">
        <location>
            <begin position="9"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="domain" description="Tyr recombinase" evidence="11">
        <location>
            <begin position="113"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="153"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="188"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="257"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="260"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="283"/>
        </location>
    </feature>
    <feature type="active site" description="O-(3'-phospho-DNA)-tyrosine intermediate" evidence="9">
        <location>
            <position position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PRC94445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="314" mass="34835" checksum="6923E054B28E0E6E" modified="2018-07-18" version="1">MNTATETTPVLHPDCVSFLAYLRDIRHYSPHTISSYRTDLISLSALFASTPPHQVSTLQIRKLTSQLHSKQLQARSIARHLSCWRSFFSWLSNHTDTEINPVIGIKAPKRSKSLPKALSVDEAVHLVEHALGTSASQAADHAMFELLYSSGLRVSELVNLDIGYCKEAAYTSSGWIDLAEQMVHVTGKGNKVREVPIGSSAITALQHWLGQRPSLLKLEPHALFLTSRGTRMSARLVQLRIKAHAQQLEIKSNVHPHVLRHSFASHVLQSSGDLRAVQELLGHSSLASTQVYTALDFQHLSQVYDAAHPRAKTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3B8</accession>
    <name>A0A2S9H3B8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1081</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94460">
        <property type="protein sequence ID" value="PRC94460"/>
        <property type="gene ID" value="S2091_1081"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008641">
        <property type="term" value="F:ubiquitin-like modifier activating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045886">
        <property type="entry name" value="ThiF/MoeB/HesA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000594">
        <property type="entry name" value="ThiF_NAD_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035985">
        <property type="entry name" value="Ubiquitin-activating_enz"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953">
        <property type="entry name" value="PTHR10953"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00899">
        <property type="entry name" value="ThiF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69572">
        <property type="entry name" value="SSF69572"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ThiF" evidence="1">
        <location>
            <begin position="9"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="253" mass="27117" checksum="E02DEB96C52743A5" modified="2018-07-18" version="1">MNDQQLLRYSRHILLDEIGIEGQSRLLASKALIIGAGGLGSPAAFYLASAGVGSITLIDHDQVDLTNLQRQILHTEERVGLNKVDSAKLTLAQLNPHIQIHALCEKADAARLCELVQQADVVLDCSDNFATRHAVNAACVAHKKPLVSGAAISFDGQCSVFDVRQADAPCYACIFPAELHFEEVACSTMGVFAPLVGIIGTVQAAEALKLLMHVGTSLAGKLLLLDARSMEWQQIKAKRNPHCAVCGPVHQNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3C3</accession>
    <name>A0A2S9H3C3_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Phosphoenolpyruvate carboxykinase [GTP]</fullName>
            <shortName evidence="9">PEP carboxykinase</shortName>
            <shortName evidence="9">PEPCK</shortName>
            <ecNumber evidence="9">4.1.1.32</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">GTP-dependent phosphoenolpyruvate carboxykinase</fullName>
            <shortName evidence="9">GTP-PEPCK</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">pckG</name>
        <name evidence="12" type="ORF">S2091_0488</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>GTP + oxaloacetate = CO2 + GDP + phosphoenolpyruvate</text>
            <dbReference type="Rhea" id="RHEA:10388"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="EC" id="4.1.1.32"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="9">Binds 1 Mn(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="9">Carbohydrate biosynthesis; gluconeogenesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.32" evidence="9"/>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94485">
        <property type="protein sequence ID" value="PRC94485"/>
        <property type="gene ID" value="S2091_0488"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00138"/>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004613">
        <property type="term" value="F:phosphoenolpyruvate carboxykinase (GTP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00819">
        <property type="entry name" value="PEPCK_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.449.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.228.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00452">
        <property type="entry name" value="PEPCK_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018091">
        <property type="entry name" value="PEP_carboxykin_GTP_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013035">
        <property type="entry name" value="PEP_carboxykinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008209">
        <property type="entry name" value="PEP_carboxykinase_GTP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035077">
        <property type="entry name" value="PEP_carboxykinase_GTP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035078">
        <property type="entry name" value="PEP_carboxykinase_GTP_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008210">
        <property type="entry name" value="PEP_carboxykinase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11561">
        <property type="entry name" value="PTHR11561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00821">
        <property type="entry name" value="PEPCK_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17297">
        <property type="entry name" value="PEPCK_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001348">
        <property type="entry name" value="PEP_carboxykinase_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF68923">
        <property type="entry name" value="SSF68923"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00505">
        <property type="entry name" value="PEPCK_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 9" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="2 9" id="KW-0312">Gluconeogenesis</keyword>
    <keyword evidence="6 9" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="12" id="KW-0418">Kinase</keyword>
    <keyword evidence="8 9" id="KW-0456">Lyase</keyword>
    <keyword evidence="7 9" id="KW-0464">Manganese</keyword>
    <keyword evidence="3 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PEPCK_N" evidence="11">
        <location>
            <begin position="24"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="domain" description="PEPCK_GTP" evidence="10">
        <location>
            <begin position="247"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="9">
        <location>
            <begin position="222"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="9">
        <location>
            <begin position="394"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="275"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="83"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="231"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="251"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="273"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="274"/>
            <end position="279"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="300"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="396"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="427"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="524"/>
            <end position="527"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF17297"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PRC94485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="616" mass="67393" checksum="8CAE890E4251B167" modified="2018-07-18" version="1">MTQATSTIALNVPSYVKQQKLISWVAEVAALTKPAKVVWCDGSQEESDALCAEMVAAGTMKKLNEEKRPNSYLACSDPSDVARVEDRTFICSAKKEDAGPTNNWMEPAEMRATLNGLFDGCMQGRTMYVVPFSMGPIGSPIAHIGVELSDSPYVAVNMRVMTRMGKAVFDVLSTDGAFVPCVHSVGAPLAAGQQDVSWPCNPNKYIVHYPETREIWSFGSGYGGNALLGKKCFALRIASNMGRDQGWLAEHMLILGVESPAGKKHYVAAAFPSACGKTNFAMLIPPASLNGWKVTTIGDDIAWIKPGADGRLYAINPEAGYFGVAPGTNTLTNYNCMASLNANTIFTNVALTDDGDVWWEGLSKQAPAHLIDWQGKDWTPEIAKETGRKAAHPNARFTVPATQNPVIDSAWDDPAGVPISAFIFGGRRSTTVPLVTEARNWVEGVYMAATMGSETTAAAVGQQGVVRRDPFAMLPFTGYNMSDYFQHWLDIGKKIAASPAEIPKIYCVNWFRTNAEGKFVWPGYSDNMRVLKWMVERVEGEAAGDENIFGITPKFADLSWDGLEFTQQQFDTITSIDKSAWDAELKLHAELFEKLEYHLPSELKTTKAQLEKRLSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3W0</accession>
    <name>A0A2S9H3W0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC-type sugar transport system permease component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_0660</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94657">
        <property type="protein sequence ID" value="PRC94657"/>
        <property type="gene ID" value="S2091_0660"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008643">
        <property type="term" value="P:carbohydrate transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="9"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="73"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="108"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="148"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="188"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="217"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="251"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="70"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC94657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="282" mass="31471" checksum="6045F88A0B490A91" modified="2018-07-18" version="1">MNKRKTNALLLNSLTWAVVVLSLLPIFWMVLSSLRNYSDIADGDQLDAGLPLQWQNYIDMWVNVDFFNFFKNSLIVCSITTLLATLSATCAAYALARFRFRGSNTVSVGITVTQVIPGMLFFLPLYMLYRQVGESWGIPMLDTYHGLIFLYVALFTPASIWIMRGFFISIPRELEDAAIIDGCSRFGAFVRIVLPISAPGIIATATFIFLLAWDELFFAWTLTSSSSVQTIPVGIRLFIGQYQHRYDLMMAAATVSTVPVLIAFFACQRFFIKGLAAGAVKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3X5</accession>
    <name>A0A2S9H3X5_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">2-methylisocitrate lyase</fullName>
            <shortName evidence="3">2-MIC</shortName>
            <shortName evidence="3">MICL</shortName>
            <ecNumber evidence="3">4.1.3.30</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">(2R,3S)-2-methylisocitrate lyase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">prpB</name>
        <name evidence="5" type="ORF">S2091_0673</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.</text>
    </comment>
    <comment type="function">
        <text evidence="3">Involved in the catabolism of short chain fatty acids (SCFA) via the 2-methylcitrate cycle (propionate degradation route). Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate via an alpha-carboxy-carbanion intermediate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3 4">
            <text>(2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate = pyruvate + succinate</text>
            <dbReference type="Rhea" id="RHEA:16809"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:57429"/>
            <dbReference type="EC" id="4.1.3.30"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 4">Organic acid metabolism; propanoate degradation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homotetramer; dimer of dimers.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 3 4">Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.3.30" evidence="3"/>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94670">
        <property type="protein sequence ID" value="PRC94670"/>
        <property type="gene ID" value="S2091_0673"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00946"/>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046421">
        <property type="term" value="F:methylisocitrate lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019629">
        <property type="term" value="P:propionate catabolic process, 2-methylcitrate cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00377">
        <property type="entry name" value="ICL_PEPM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01939">
        <property type="entry name" value="PrpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039556">
        <property type="entry name" value="ICL/PEPM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018523">
        <property type="entry name" value="Isocitrate_lyase_ph_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012695">
        <property type="entry name" value="PrpB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_Kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="SSF51621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02317">
        <property type="entry name" value="prpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00161">
        <property type="entry name" value="ISOCITRATE_LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 5" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="3">
        <location>
            <begin position="45"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="3">
        <location>
            <begin position="123"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="3">
        <location>
            <begin position="210"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="85"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="87"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="158"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="188"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="241"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="270"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC94670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="296" mass="32169" checksum="82D57CB9DEE960AA" modified="2018-07-18" version="1">MSHYSAGAAFRRAVKEEAPLQVVGAINANHALLAKRAGFKAIYLSGGGVAAGSLGLPDLGISNLDDVLTDVRRITDVCDLPLLVDIDTGFGASAFNVARTVKSMIKFGAAAVHMEDQVGAKRCGHRPGKEIVSTQEMVDRIKAAVDARTDPEFVIMARTDALAVEGFDAALERAHAYVEAGADMVFPEAITELAMYQRFASKLQVPILANITEFGSTPLFTVDELKSVDVGLVLYPLSAFRAMNKAAENVYNAIRHDGTQKNVVDTMQTRMELYERINYHTFEQKLDALFAQQKSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H408</accession>
    <name>A0A2S9H408_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0710</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94707">
        <property type="protein sequence ID" value="PRC94707"/>
        <property type="gene ID" value="S2091_0710"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="29" mass="3360" checksum="C0147BBB588CB102" modified="2018-07-18" version="1">MLNILIIVCGFIGVALSLIVKIFYFFKRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H477</accession>
    <name>A0A2S9H477_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0787</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94784">
        <property type="protein sequence ID" value="PRC94784"/>
        <property type="gene ID" value="S2091_0787"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="31"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="50" mass="4891" checksum="8A164E7E47542D03" modified="2018-07-18" version="1">MINFKKKLAPRSLIYLSSAVLLVILSACGGGHGGGGAPVGPGSTMAGTSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4A4</accession>
    <name>A0A2S9H4A4_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">N-succinylarginine dihydrolase</fullName>
            <ecNumber evidence="2">3.5.3.23</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">astB</name>
        <name evidence="3" type="ORF">S2091_0004</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>2 H(+) + 2 H2O + N(2)-succinyl-L-arginine = CO2 + N(2)-succinyl-L-ornithine + 2 NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:19533"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:58241"/>
            <dbReference type="ChEBI" id="CHEBI:58514"/>
            <dbReference type="EC" id="3.5.3.23"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid degradation; L-arginine degradation via AST pathway; L-glutamate and succinate from L-arginine: step 2/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the succinylarginine dihydrolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.3.23" evidence="2"/>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94809">
        <property type="protein sequence ID" value="PRC94809"/>
        <property type="gene ID" value="S2091_0004"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00185">
        <property type="reaction ID" value="UER00280"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009015">
        <property type="term" value="F:N-succinylarginine dihydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019544">
        <property type="term" value="P:arginine catabolic process to glutamate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019545">
        <property type="term" value="P:arginine catabolic process to succinate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.75.10.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01172">
        <property type="entry name" value="AstB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037031">
        <property type="entry name" value="AstB_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007079">
        <property type="entry name" value="SuccinylArg_d-Hdrlase_AstB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04996">
        <property type="entry name" value="AstB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03241">
        <property type="entry name" value="arg_catab_astB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0056">Arginine metabolism</keyword>
    <keyword evidence="2 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="20"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="138"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="175"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="251"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="2">
        <location>
            <position position="372"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="111"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="215"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="253"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="366"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022503"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="446" mass="48297" checksum="D0C12807ACACE5E0" modified="2018-07-18" version="1">MQKTREYNFDGLVGPTHNYAGLSFGNVASSSNIKSASNPKEAALQGLAKMHALAQRGFAQALLPPQDRPNFKLLRQLGFTGTNAQMIEAAARTSPVLLACAYSASSMWTANAATVSPSADTADGRTHFTVANLNNKLHRSIEHSQTERALRAIFHDEKHFAVHQALPATPAFGDEGAANHTRLCAEHGAAGVELFVYGRSEFDASIVGPKKFPARQTLEASQAVARLHGLQDARTVFVQQNPHTIDQGVFHNDVIAVGSGNVLFYHQEAFVDEAASIEKCRIAMQQVGAELNPIRVATAQVVVADAVSSYLFNSQLLAKPNGKMALLVPQECSENAAVAAYLKDLVSSTGAIDELLSFELRQSMRNGGGPACLRLRVALTEQQANAMHQGVIFTEALYKRLVTWVESHYRDTLFPDDMADPALAIEVQTALNELSGILNLPNLYEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4C9</accession>
    <name>A0A2S9H4C9_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Lipopolysaccharide export system protein LptA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">lptA</name>
        <name evidence="6" type="ORF">S2091_0796</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Component of the lipopolysaccharide transport and assembly complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the LptA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94793">
        <property type="protein sequence ID" value="PRC94793"/>
        <property type="gene ID" value="S2091_0796"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001530">
        <property type="term" value="F:lipopolysaccharide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043165">
        <property type="term" value="P:Gram-negative-bacterium-type cell outer membrane assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015920">
        <property type="term" value="P:lipopolysaccharide transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01914">
        <property type="entry name" value="LPS_assembly_LptA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014340">
        <property type="entry name" value="LptA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005653">
        <property type="entry name" value="OstA-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03968">
        <property type="entry name" value="LptD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03002">
        <property type="entry name" value="outer_YhbN_LptA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0574">Periplasm</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="1 3" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015790525" description="Lipopolysaccharide export system protein LptA" evidence="3">
        <location>
            <begin position="22"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="domain" description="OstA-like_N" evidence="5">
        <location>
            <begin position="31"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="179"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="181"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC94793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="212" mass="23035" checksum="4DA24F87BDD70E0A" modified="2018-07-18" version="1" precursor="true">MIKHLSLSFLLLSLAISTAHAEKADSQQPLHISAESQTYDGNKKVTVYTGSVHMVKGTLIINAARLEVVEDANGGKIGTLFSGPGKLVNYRQKRDGGPDLWAEGEADKVVYDDTLELIKLFNQAKLVLLDGKKRTHESSGIYISYDSRTDFMSVNNTLQGISAPGAGFTNAVIYPVEDKPKAAPVKVEPKVETKVDSKTEPKPATKPEVTHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4D0</accession>
    <name>A0A2S9H4D0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0040</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94845">
        <property type="protein sequence ID" value="PRC94845"/>
        <property type="gene ID" value="S2091_0040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08417">
        <property type="entry name" value="PBP2_Nitroaromatics_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037402">
        <property type="entry name" value="YidZ_PBP2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="19"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="332" mass="37380" checksum="A3BA21F53038AE29" modified="2018-07-18" version="1">MILKLHGCPNKKTVLLSAFNLNLLRSLDVLIETRNLTTAAKVLGLTQSTLSRQLVQLREQTGDPLLIREGQRFLLTQKAEALRGPLKNILANMETLLDTPHFDPAQCARQFSICGSDYIADHMLPELVRNLASQAPQLRIVLRMWEPGHYRLLADEGVDLVPTIADMIPDNLYGRSLGEDKAVCVMRTNHPLAKNSKLSLQDYVDSPHISIAGGSDKNSLVDQALGRQGLKRDIRLNVPFYAAALKLLIDNDLLLTIPVHIAIALARNSAIVWQPLPFDVAPYRYWLLWHARNHHDPAHQWFRNQVVEVLNHSMYGVTKFNAISDDLIQPPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4H5</accession>
    <name>A0A2S9H4H5_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Deoxyuridine 5'-triphosphate nucleotidohydrolase</fullName>
            <shortName evidence="4">dUTPase</shortName>
            <ecNumber evidence="4">3.6.1.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">dUTP pyrophosphatase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">dut</name>
        <name evidence="6" type="ORF">S2091_0062</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 4">
            <text>dUTP + H2O = diphosphate + dUMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10248"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61555"/>
            <dbReference type="ChEBI" id="CHEBI:246422"/>
            <dbReference type="EC" id="3.6.1.23"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Pyrimidine metabolism; dUMP biosynthesis; dUMP from dCTP (dUTP route): step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the dUTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.23" evidence="4"/>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94867">
        <property type="protein sequence ID" value="PRC94867"/>
        <property type="gene ID" value="S2091_0062"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00610">
        <property type="reaction ID" value="UER00666"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004170">
        <property type="term" value="F:dUTP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006226">
        <property type="term" value="P:dUMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046081">
        <property type="term" value="P:dUTP catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07557">
        <property type="entry name" value="trimeric_dUTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00116">
        <property type="entry name" value="dUTPase_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008181">
        <property type="entry name" value="dUTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029054">
        <property type="entry name" value="dUTPase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036157">
        <property type="entry name" value="dUTPase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033704">
        <property type="entry name" value="dUTPase_trimeric"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11241">
        <property type="entry name" value="PTHR11241"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00692">
        <property type="entry name" value="dUTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51283">
        <property type="entry name" value="SSF51283"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00576">
        <property type="entry name" value="dut"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 4" id="KW-0546">Nucleotide metabolism</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="dUTPase" evidence="5">
        <location>
            <begin position="15"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="4">
        <location>
            <begin position="68"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="4">
        <location>
            <begin position="85"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="81"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC94867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="149" mass="15875" checksum="CB775AB8A9EB6300" modified="2018-07-18" version="1">MKKIAVKIIDQRMQDQLPAYATAGSAGLDLRACIDAPITIQAGQTVLIPTGLAIHLADPGYAAMILPRSGMGHKNGIVLGNLVGLIDSDYQGQLMVSTWNRGNSEFTLQPMERLAQLIIVPVLQVGFEVVEEFADSTRGEGGFGSTGKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4I5</accession>
    <name>A0A2S9H4I5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="13">ABC-type bacteriocin/lantibiotic exporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">S2091_0072</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94877">
        <property type="protein sequence ID" value="PRC94877"/>
        <property type="gene ID" value="S2091_0072"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008234">
        <property type="term" value="F:cysteine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02419">
        <property type="entry name" value="Peptidase_C39C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033838">
        <property type="entry name" value="CvaB_peptidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005074">
        <property type="entry name" value="Peptidase_C39"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="PTHR24221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03412">
        <property type="entry name" value="Peptidase_C39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="SSF90123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50990">
        <property type="entry name" value="PEPTIDASE_C39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-1278">Translocase</keyword>
    <keyword evidence="2 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="155"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="192"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="270"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="297"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="377"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase C39" evidence="12">
        <location>
            <begin position="6"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="11">
        <location>
            <begin position="159"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="471"/>
            <end position="704"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="505"/>
            <end position="512"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PRC94877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="717" mass="79054" checksum="5FC6C7EB19EE34AD" modified="2018-07-18" version="1">MKLILQTEASECGLACLAMVANHYGYHSDLADLRRQFSVSLKGATLAQIMRHAAGMELSARPLRLELDELSKLTLPCILHWNLNHFVVLKKVTKKGIAILDPTVGELRVGMKEVSRHFTGVALELAPSPSFKPKEESKKIAVRDLTGKVVGLRRALLQVLVLALALEIFAICAPLFNQFVIDEVIVSGDRELLTVLVAGFALLMVTQTLIGLARSWFLMRWSMDIGFQWASRVFAHLTQLPVAFFEKRHLGDVVSRFGSINSIQETLTSLFVESALDGLMAILALGMMLIYSPKLTLLVVIASALYGLLRWAFYMPFREASQERLVLSAKENTHFLETLRAISPLKLFGREAERRARWQNLKLDVMNRDIKTQKLSIIFKVSNTAIFGAQGLALFYIGAGLVMQNALTVGMLMAFSSYATTFSGRISSLIDLMVDLKMIGLHAERLADIVLEPVESQAGMETDTSRLQASITLRDVKFRYADGEPWVLNGINLTIPAGQSVALVGESGCGKTTLCKIIVGLLKPTEGEVLIDQIPIQQLGLPAYRKLVGTVMQDDVLLAGSIQDNISFFDAQIQTARVQECARQAAIHDEIVVMPMGYQTLVGDMGSSLSGGQKQRVLLARALYKQPIILALDEATSHLDIANEQRVNQALSQLQLTRIMVAHRPETIAAAQRVVEIVMGQVREVHTQDITLLPIRVATYSDAAYQASNYRVTISAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4M0</accession>
    <name>A0A2S9H4M0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_0129</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94934">
        <property type="protein sequence ID" value="PRC94934"/>
        <property type="gene ID" value="S2091_0129"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004638">
        <property type="entry name" value="EmrB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00711">
        <property type="entry name" value="efflux_EmrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="56"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="85"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="111"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="144"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="173"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="205"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="230"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="268"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="305"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="338"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="362"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="407"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="433"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="20"/>
            <end position="461"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC94934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="464" mass="49277" checksum="ACAE5081039CF1B3" modified="2018-07-18" version="1">MSNTTSLNASEGINPQVWKVAAVVIVGPFMTQMDSTVVNVSLSAIRMELHSSIATAQWIIGGYLLALALMLPLSGWLVDRIGAKRLYLGCFSVFTLASLLCGSARTMEELIGARLIQGIAGGLLAPMTQMMIARVAGKHMARVLGYLVVPIMIAPIIGPVLAGAILKYTSWPWLFYINLPIGVLGLLLASLLLPSDETSIQKRPFDLLGFLLISPGLACLLYGLQHASDSDGKLILLLGSVLTMAFIWHAKRKGSAALIDLELFHNRIFSTAAMTQFLSNGMFYARQFLIPLYLITGCALSPSKAGSMIAAMGLGMMCSFPLMGWLTGRFGCRAVSTGGALLALLGMLPFVWMIQYEFSSTLTVVSLFVAGAGHGMINIPSVSAAYASVSRDKLAVANTALNIAQRLGGPVATTVLAIVMSLAASIYPASGPHSFMTAFVLVIALHLLALVSASRLPISMHTPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H514</accession>
    <name>A0A2S9H514_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glutamate-1-semialdehyde 2,1-aminomutase</fullName>
            <shortName evidence="7">GSA</shortName>
            <ecNumber evidence="7">5.4.3.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Glutamate-1-semialdehyde aminotransferase</fullName>
            <shortName evidence="7">GSA-AT</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">hemL</name>
        <name evidence="9" type="ORF">S2091_0269</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>(S)-4-amino-5-oxopentanoate = 5-aminolevulinate</text>
            <dbReference type="Rhea" id="RHEA:14265"/>
            <dbReference type="ChEBI" id="CHEBI:57501"/>
            <dbReference type="ChEBI" id="CHEBI:356416"/>
            <dbReference type="EC" id="5.4.3.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; 5-aminolevulinate from L-glutamyl-tRNA(Glu): step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.3.8" evidence="7"/>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95074">
        <property type="protein sequence ID" value="PRC95074"/>
        <property type="gene ID" value="S2091_0269"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00251">
        <property type="reaction ID" value="UER00317"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042286">
        <property type="term" value="F:glutamate-1-semialdehyde 2,1-aminomutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006782">
        <property type="term" value="P:protoporphyrinogen IX biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00610">
        <property type="entry name" value="OAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00375">
        <property type="entry name" value="HemL_aminotrans_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004639">
        <property type="entry name" value="4pyrrol_synth_GluAld_NH2Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00713">
        <property type="entry name" value="hemL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00600">
        <property type="entry name" value="AA_TRANSFER_CLASS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6 7" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="4 7 8" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="7">
        <location>
            <position position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008981"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC95074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="428" mass="45392" checksum="1A5991C7692391A7" modified="2018-07-18" version="1">MRNTELFERAQLTTPGGVNSPVRAFRSVGGTPRFITRAEGAYFWDAEQKRYIDYIGSWGPAIVGHAHPEVVKAVQAAAALGLSFGAPTEGEVLMAEEICKLVPSIEQVRLVSSGTEATMSALRLARGATGRDKIIKFEGCYHGHADALLVKAGSGLLTLGNPSSSGVPADFTKHTLVLDYNNTQQLEDTFKAIGDQIACVIVEPVAGNMNLIKATPEFLQTMRRLCTEHGTVLIFDEVMCGFRVALGGAQALYNIKPDLTALGKVIGGGLPVAAFGGRADLMAHMAPLGGVYQAGTLSGNPVAVAAGLTTLKLIQADGFYENLSAQTNKLAQGLSAAAQQAGVTFCADSIGGMFGMYFAKQVPATYAAMMETDKEKFNRFFHLMLDNGVYLAPSAYEAGFVSAQHDDAIIQATLDVAKQAFAQLKLSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H592</accession>
    <name>A0A2S9H592_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Gram-negative porin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_0288</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95093">
        <property type="protein sequence ID" value="PRC95093"/>
        <property type="gene ID" value="S2091_0288"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046930">
        <property type="term" value="C:pore complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015288">
        <property type="term" value="F:porin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006811">
        <property type="term" value="P:ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00342">
        <property type="entry name" value="gram_neg_porins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033900">
        <property type="entry name" value="Gram_neg_porin_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023614">
        <property type="entry name" value="Porin_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002299">
        <property type="entry name" value="Porin_Neis"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13609">
        <property type="entry name" value="Porin_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00184">
        <property type="entry name" value="NEISSPPORIN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0406">Ion transport</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0626">Porin</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1134">Transmembrane beta strand</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015605195" evidence="5">
        <location>
            <begin position="20"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="domain" description="Porin_4" evidence="6">
        <location>
            <begin position="7"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF13609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC95093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="364" mass="38331" checksum="D9F8C514A27952F7" modified="2018-07-18" version="1">MKKSLLAVALLGAFGVASAQSSVTVYGTMDAGVGYTNGANAAGTQTTLESGQQSYSRIGFKGTEDLGGGLKALFVLEQGVQLDTGSSGYNTTGSNTSTSTTSGNTGTFSSQAYVGLGGNFGTVKLGRQFSPLYETYASIDPFQNGFSANINNFFGNSSSTTSVAAGGNVASYQRMSNAVTYSTPDNLYGFKGTVAYGFGEQAGDTSAQSQVGASLSYINGPLTVAYAYHQANNDTVVGSVATPGETFKTNFIGAAYDFNVVKVHAAFDQNQQADQTLKTQDYMLGVTVPFGAHSVFADYTHKDNKLVQNADADQYAIGYTYTLSKRTNLYTSYSYVKNKEDSYINTDVAGNSVSTFQVGMRHSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5L6</accession>
    <name>A0A2S9H5L6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0462</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95267">
        <property type="protein sequence ID" value="PRC95267"/>
        <property type="gene ID" value="S2091_0462"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002397">
        <property type="entry name" value="Cyt_P450_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00359">
        <property type="entry name" value="BP450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="SSF48264"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0349">Heme</keyword>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC95267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="393" mass="43107" checksum="C69C803A0FC1DD74" modified="2018-07-18" version="1">MNSINSIAALNTATNPYPDYCALLSGPELVFNEQLQCWVASRAAVVDEVFNNPYCLVRPSAEQVPKTLVGSSAGDIFARLIRMNEGNAHACPKLATLKALNTLDGLRISICTNEMIALLAAKYALSDGAYLAAWMFDLPIYVVAKLLGFNDVELPRVAEWARDFVCGISPLGNAEQLNSASVAARALLLRFRVLIECAPVQEKSLLSHLLQEAQLAGWDNCDAILANLIGFLSQTYEATAGLIGNGFIALFNRPELQLLISRDISQMDHLVQEVCRFDPPVQNTRRFVAQATIVANQHLQAGDSILVLLAAASRDEQVNARPDEFILERTNRRLFVFGHGRHACPGQNLSCTIASAALSGLLPLLVDIKQLNWTYRPSFNVRVPEFTVITKRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5M5</accession>
    <name>A0A2S9H5M5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="9">ABC-type spermidine/putrescine transport systems ATPase component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_0479</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95284">
        <property type="protein sequence ID" value="PRC95284"/>
        <property type="gene ID" value="S2091_0479"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015408">
        <property type="term" value="F:ABC-type ferric iron transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03259">
        <property type="entry name" value="ABC_Carb_Solutes_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015853">
        <property type="entry name" value="ABC_transpr_FbpC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008995">
        <property type="entry name" value="Mo/tungstate-bd_C_term_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013611">
        <property type="entry name" value="Transp-assoc_OB_typ2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08402">
        <property type="entry name" value="TOBE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50331">
        <property type="entry name" value="SSF50331"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-1278">Translocase</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="8">
        <location>
            <begin position="5"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="37"/>
            <end position="44"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC95284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="354" mass="39384" checksum="40700EC207E91FBD" modified="2018-07-18" version="1">MMPLLELQQVAHSYSSKTTFSELSFKLMKGQIACLLGPSGCGKTTALRCIAGFEEISSGAILINNQLVSRAGFNQPAEQRQIGMIFQDYALFPHLNVARNISFGLFKFGAAQRQQRVDELLEIVGLSGYAKAYPHQLSGGQQQRVALARALAPRPALLLLDEPFSNLDVELRERLCIEIRTILKRQNSTAILVTHDQHEAFAMADEIGVMHQGSMQQWDSADQLYHQPSNRFVANFIGEGGFIDGQVINEHQIEIELGLVRNQRGHPRGSSIELLLRPDDIVQSERSNLRAKVVGKAFRGADCLYTLELPSGQRVLSRIPSHYPHAIDDYIGIELEIKPDVEHVITFQKSGISS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GS90</accession>
    <name>A0A2S9GS90_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Site-specific recombinase XerD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_4696</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000046">
        <property type="protein sequence ID" value="PRC90589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90589">
        <property type="protein sequence ID" value="PRC90589"/>
        <property type="gene ID" value="S2091_4696"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044068">
        <property type="entry name" value="CB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002104">
        <property type="entry name" value="Integrase_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010998">
        <property type="entry name" value="Integrase_recombinase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00589">
        <property type="entry name" value="Phage_integrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51900">
        <property type="entry name" value="CB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51898">
        <property type="entry name" value="TYR_RECOMBINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0229">DNA integration</keyword>
    <keyword evidence="3" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="2 4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core-binding (CB)" evidence="6">
        <location>
            <begin position="21"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="domain" description="Tyr recombinase" evidence="5">
        <location>
            <begin position="134"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC90589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="336" mass="38230" checksum="CA62257AA7096E35" modified="2018-07-18" version="1">MALRKKHHGGATSRGWDLPNIPLATALQAFLAWSETGGVSPFTLRQRQRGVRRFIVWAQERGLTSPHEITLPILERYQRHLYHYRKTDGMPLSIASQHTELVPLKAYFKWLARGKQIQYNPAAELEMPKIPRKIPRYVLTVQEVETVLNQTDTQTPMGLRDRAMMEVLYSSGIRRSELAKLDMTDIDTNRGSLLVREGKGKRDRLVPLGARACAWVTRYLLEVRPELCDTAICQSLFLTDYGTQFEVDWLGEHLKRYIQSAGIVAPGACHLFRHACATHMLENGADIRFIQVLLGHASLTSTQIYTSVSIQKLKQIHDATHPARIERLNTTPDSNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSC6</accession>
    <name>A0A2S9GSC6_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">Recombination-associated protein RdgC</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rdgC</name>
        <name evidence="6" type="ORF">S2091_4660</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 5">May be involved in recombination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 5">Cytoplasm</location>
            <location evidence="2 5">Nucleoid</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 5">Belongs to the RdgC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000042">
        <property type="protein sequence ID" value="PRC90624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90624">
        <property type="protein sequence ID" value="PRC90624"/>
        <property type="gene ID" value="S2091_4660"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009295">
        <property type="term" value="C:nucleoid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00194">
        <property type="entry name" value="RdgC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007476">
        <property type="entry name" value="RdgC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38103">
        <property type="entry name" value="PTHR38103"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04381">
        <property type="entry name" value="RdgC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC90624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="311" mass="34841" checksum="86499D5C64B71282" modified="2018-07-18" version="1">MPCRIEDFLIGLIMWFKNLQIYRLPAPWKFDIEQLTAQLATQAFQPCSNSEMQSQGWIAPRQNGDLVHSVNRQLLLQLSTERKLLPNSVINQVTKARALEVEEQQGFKPGRKLLKELKEQVTEELMPRAFSIQRATAVWIDPVNGWLVIDASSPSRSDEVLKLLLKCIDQLPLESLRVNLSPLGAMTDWLAGNEAPAGFTIDQDTELRSSAESKATVRYVRHTLDPKEIASHIAGGKQCTKLALTWADKVSFVLTENLAIKRVQALDVLTEKSDSHHEDEKLDGDFALMCGELNQLFGDLVLALGGETKPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSG6</accession>
    <name>A0A2S9GSG6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4640</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000040">
        <property type="protein sequence ID" value="PRC90657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90657">
        <property type="protein sequence ID" value="PRC90657"/>
        <property type="gene ID" value="S2091_4640"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC90657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="182" mass="20109" checksum="C4F8B4AD722634E3" modified="2018-07-18" version="1">MMNLELDWAAPIVPGQSMMGLHLGMSYSDVLTALQFYRVDVSEGNNDFLVRIKNSPLLLVEMLSDGIILRDTISKSPNATSFDKLFVMGFKEGVLVHLMTSLIYGASFDYYKGLIFGKVGIGSPVANIRKFCEVEFDSGDELFYPIDDAFVGFSIGGSCSSLEEDPDQLVSYIRIYVSALNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSK9</accession>
    <name>A0A2S9GSK9_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ribosomal protein S12 methylthiotransferase RimO</fullName>
            <shortName evidence="8">S12 MTTase</shortName>
            <shortName evidence="8">S12 methylthiotransferase</shortName>
            <ecNumber evidence="8">2.8.4.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Ribosome maturation factor RimO</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">rimO</name>
        <name evidence="12" type="ORF">S2091_4628</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>[sulfur carrier]-SH + AH2 + L-aspartate(89)-[ribosomal protein uS12]-hydrogen + 2 S-adenosyl-L-methionine = 3-methylsulfanyl-L-aspartate(89)-[ribosomal protein uS12]-hydrogen + 5'-deoxyadenosine + [sulfur carrier]-H + A + 2 H(+) + L-methionine + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:37087"/>
            <dbReference type="Rhea" id="RHEA-COMP:10460"/>
            <dbReference type="Rhea" id="RHEA-COMP:10461"/>
            <dbReference type="Rhea" id="RHEA-COMP:14737"/>
            <dbReference type="Rhea" id="RHEA-COMP:14739"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:29917"/>
            <dbReference type="ChEBI" id="CHEBI:29961"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:64428"/>
            <dbReference type="ChEBI" id="CHEBI:73599"/>
            <dbReference type="EC" id="2.8.4.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="8">Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the methylthiotransferase family. RimO subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.8.4.4" evidence="8"/>
    <dbReference type="EMBL" id="PUGF01000039">
        <property type="protein sequence ID" value="PRC90678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90678">
        <property type="protein sequence ID" value="PRC90678"/>
        <property type="gene ID" value="S2091_4628"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0103039">
        <property type="term" value="F:protein methylthiotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018339">
        <property type="term" value="P:peptidyl-L-beta-methylthioaspartic acid biosynthetic process from peptidyl-aspartic acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01865">
        <property type="entry name" value="MTTase_RimO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005839">
        <property type="entry name" value="Methylthiotransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020612">
        <property type="entry name" value="Methylthiotransferase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013848">
        <property type="entry name" value="Methylthiotransferase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038135">
        <property type="entry name" value="Methylthiotransferase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005840">
        <property type="entry name" value="Ribosomal_S12_MeSTrfase_RimO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041582">
        <property type="entry name" value="RimO_TRAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023404">
        <property type="entry name" value="rSAM_horseshoe"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002792">
        <property type="entry name" value="TRAM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43837">
        <property type="entry name" value="PTHR43837"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18693">
        <property type="entry name" value="TRAM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00919">
        <property type="entry name" value="UPF0004"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01061">
        <property type="entry name" value="methylthiotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00274">
        <property type="entry name" value="ribosomal_protein_S12_methylth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00089">
        <property type="entry name" value="TIGR00089"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01125">
        <property type="entry name" value="TIGR01125"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51449">
        <property type="entry name" value="MTTASE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01278">
        <property type="entry name" value="MTTASE_RADICAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50926">
        <property type="entry name" value="TRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 8" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="2 8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8" id="KW-0408">Iron</keyword>
    <keyword evidence="7 8" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="12" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4 8" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 8 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="MTTase N-terminal" evidence="10">
        <location>
            <begin position="8"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="domain" description="Radical SAM core" evidence="11">
        <location>
            <begin position="140"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="domain" description="TRAM" evidence="9">
        <location>
            <begin position="384"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="17"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="53"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="82"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="154"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="158"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="161"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PRC90678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="453" mass="50169" checksum="6FC29151DABE57A3" modified="2018-07-18" version="1">MQDSPISPKIGFVSLGCPKALVDSEQILTQLRAEGYETAKSYDGADLVIVNTCGFIDAAVQESLDAIGEALHENGKVIVTGCLGAKKDAQGLDMIRTIHPKVLEVTGPHALTEVMAAVHKHLPKPHDPFLDLVPAQGVKLTPKHYAYLKISEGCNHRCSFCIIPSMRGDLVSRPIAELMLEAENLFKAGVKELLVISQDTSAYGVDVKFRMGFWNGKPVKTHMTQLVEALGELAKQYGAWVRLHYVYPYPHVDQIIPHMQEGLILPYLDVPLQHAHPDVLKRMKRPASGEKNLDRIQAWRKMCPDLTIRSTLIAGFPGETEAEFSYLLDFLKEAEIDRLGCFAYSPVDGATANLLANPVPEEVREERRGRVMELQEQISKKRLQAKVGTTMRVLLDEVTRQGGVGRSSADAPEIDGVVYVKAPYEPHKKLIVGEFIDVKVTTSDAHDLWAEPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSR7</accession>
    <name>A0A2S9GSR7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative membrane-bound metal-dependent hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4499</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000036">
        <property type="protein sequence ID" value="PRC90751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90751">
        <property type="protein sequence ID" value="PRC90751"/>
        <property type="gene ID" value="S2091_4499"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007404">
        <property type="entry name" value="YdjM-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04307">
        <property type="entry name" value="YdjM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="119"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="148" mass="16821" checksum="011D859FF2F9417F" modified="2018-07-18" version="1">MFPDIDVLAFRFNVAYADEFGHRGASHSLAFALLAACLLMLFSSRLKSTPLKTFLFVAISTASHGILDTFTNGGKGVALLWPFSTERFFSYWQVIEVSPLSLRRIFSDRGLQVIQSEFIWVWLPAIVLCVVLIVVRSKLRIKYFVRAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSS0</accession>
    <name>A0A2S9GSS0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Antidote-toxin recognition MazE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4515</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000036">
        <property type="protein sequence ID" value="PRC90767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90767">
        <property type="protein sequence ID" value="PRC90767"/>
        <property type="gene ID" value="S2091_4515"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007159">
        <property type="entry name" value="SpoVT-AbrB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037914">
        <property type="entry name" value="SpoVT-AbrB_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04014">
        <property type="entry name" value="MazE_antitoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89447">
        <property type="entry name" value="SSF89447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SpoVT-AbrB" evidence="1">
        <location>
            <begin position="10"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="98" mass="10886" checksum="E623C7E3A07E1527" modified="2018-07-18" version="1">MIETRIAKLFKNGSSQAVRLPLEFRFEGSEVYITRDDATGDVVLSTRPGAKTWSEFFELLHAINVPVDFMADRPLNVLPQTGGIFDDEIASHDKDGSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GT07</accession>
    <name>A0A2S9GT07_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="13">FtsK/SpoIIIE family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">S2091_4431</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Translocation stops specifically at Xer-dif sites, where FtsK interacts with the Xer recombinase, allowing activation of chromosome unlinking by recombination. FtsK orienting polar sequences (KOPS) guide the direction of DNA translocation. FtsK can remove proteins from DNA as it translocates, but translocation stops specifically at XerCD-dif site, thereby preventing removal of XerC and XerD from dif.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homohexamer. Forms a ring that surrounds DNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FtsK/SpoIIIE/SftA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000034">
        <property type="protein sequence ID" value="PRC90850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90850">
        <property type="protein sequence ID" value="PRC90850"/>
        <property type="gene ID" value="S2091_4431"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025199">
        <property type="entry name" value="FtsK_4TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041027">
        <property type="entry name" value="FtsK_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002543">
        <property type="entry name" value="FtsK_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018541">
        <property type="entry name" value="Ftsk_gamma"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13491">
        <property type="entry name" value="FtsK_4TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17854">
        <property type="entry name" value="FtsK_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09397">
        <property type="entry name" value="FtsK_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01580">
        <property type="entry name" value="FtsK_SpoIIIE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00843">
        <property type="entry name" value="Ftsk_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50901">
        <property type="entry name" value="FTSK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="31"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="78"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="163"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="domain" description="FtsK" evidence="12">
        <location>
            <begin position="414"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="431"/>
            <end position="438"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00024784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PRC90850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="773" mass="84610" checksum="B5E2CECA23C71A54" modified="2018-07-18" version="1">MSKAAYTRDPDKDKPSTKPGRMVMLLSEARWLVLVAVTAFLAMILLSYSPNDPAWSQSNQVDHIANWGGHFGAWCADLLLYVFGKSAWWWFLLLGINVARSYSQLGNMENWEPEHRYLGWLRGTGFALLFSGSMGMEYLRMYSYHFHLPRAPGGVLGEVIGNAAYSVLGFTGATLFFLVLIALGISVLFQISWLTVAEKIGTGLELSLDWIVKKYTARQDRMVGQVAATQREVVVVQERAKHVEAVPVRIEPQVVAVVRSTRVEKEKQAALFSELSDNSLPPLALLDEAKAVQETVSIETLEFTSRLIEKKLSDFGVNVKVVAAYPGPVITRYEIEPATGVKGSQIVGLARDLARSLSIISIRVVETIPGKMYMGLELPNPKRQIVRLTEILGSQLYNDSASSLTIALGKDIAGHPVVADLAKMPHLLIAGTTGSGKSVGINATLLSLLYKSDPKSVRMILIDPKMLEMSVYEGIPHLLAPVVTDMRQAGHALNWAVNEMERRYRLMSKLGVRNLAGYNSKIIEAAKREEHISNPFSLTPDAPEPLEELPTIVIIIDELADLMMVVGKKVEELIARIAQKARAAGLHLILATQRPSVDVITGLIKANIPTRIAFQVSSKIDSRTILDQMGAEALLGMGDMLYMPPGTGFPVRVHGAFVSDEEVHRVVEFLKSQGAPNYVEGILEGGVAEDGASLSIDGATGVAGGNESDELYDSAVAIVLKNRRASISLVQRNLRIGYNRAARLLEQMEQSGIVSTMQSNGNREILVPTPPQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GT40</accession>
    <name>A0A2S9GT40_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Dioxygenases related to 2-nitropropane dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4456</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000034">
        <property type="protein sequence ID" value="PRC90875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90875">
        <property type="protein sequence ID" value="PRC90875"/>
        <property type="gene ID" value="S2091_4456"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018580">
        <property type="term" value="F:nitronate monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04730">
        <property type="entry name" value="NPD_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004136">
        <property type="entry name" value="NMO"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03060">
        <property type="entry name" value="NMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NMO" evidence="1">
        <location>
            <begin position="84"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="306" mass="32917" checksum="F12D197E2218EC23" modified="2018-07-18" version="1">MSIPQILKDGLQLPVIAAPMFLVSGTRLVIETCKQGIIGTLPALNARPSSQLDDWLFEIQTALADIQAAKFGVMLPIHKSNKRLEEDLDIVIRHKVPLVITAAGHRPDVIEAVHSYGGVVFHDAIHMKHAMKAVEAGVDGIIPICAGGGGNAGILNPFTFVTQLRAEFDGTIVLGGAMGHGRHIRAAQVLGADIAYMGTRFIATEEANANPKFKQMILDAESTDVIYTNKVTGIGASFLRESLEKAGLDWREGAVIPPVTVENEEEMIAWRDIWSAGHGVGLIQDVPTVAHLAQRLKDEYSAALAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GT52</accession>
    <name>A0A2S9GT52_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Histidine utilization repressor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_4392</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000033">
        <property type="protein sequence ID" value="PRC90899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90899">
        <property type="protein sequence ID" value="PRC90899"/>
        <property type="gene ID" value="S2091_4392"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006547">
        <property type="term" value="P:histidine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006744">
        <property type="term" value="P:ubiquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07377">
        <property type="entry name" value="WHTH_GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1410.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028978">
        <property type="entry name" value="Chorismate_lyase_/UTRA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010248">
        <property type="entry name" value="His_ut_repres"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011663">
        <property type="entry name" value="UTRA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00392">
        <property type="entry name" value="GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07702">
        <property type="entry name" value="UTRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00035">
        <property type="entry name" value="HTHGNTR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00866">
        <property type="entry name" value="UTRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64288">
        <property type="entry name" value="SSF64288"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02018">
        <property type="entry name" value="his_ut_repres"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50949">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0831">Ubiquinone biosynthesis</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="3">
        <location>
            <begin position="17"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC90899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="245" mass="27420" checksum="E94DEAB4F81F2BAF" modified="2018-07-18" version="1">MTIQTAQVSRLISNSTIPAFQQIKDYIRDEIQQGAWKEGDAIPSEAVLAKQFVVSRMTVNRAVRELSNEQLLIRIQGSGTFVAQQKYQATLVAIKSIAEEVRARGHVHSSALHLLEKGKPSAQLLQQFNVETGHVLFHSVIVHFENDIPIQVEDRWVNSSLAPAYLQQNFSNITPNEYLMAAAPLQEVHYRIEAVVAPAKIAEMLAIPSTLPCLVLHRETISRSQIASIATMWHPGNRYQFAGQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTA2</accession>
    <name>A0A2S9GTA2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">PEP-CTERM protein-sorting domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_4350</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000032">
        <property type="protein sequence ID" value="PRC90949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90949">
        <property type="protein sequence ID" value="PRC90949"/>
        <property type="gene ID" value="S2091_4350"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013424">
        <property type="entry name" value="PEP_exosort_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07589">
        <property type="entry name" value="PEP-CTERM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02595">
        <property type="entry name" value="PEP_exosort"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5016258945" evidence="2">
        <location>
            <begin position="23"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="261"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="domain" description="PEP-CTERM" evidence="3">
        <location>
            <begin position="257"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC90949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="282" mass="28281" checksum="7718A5956A29412E" modified="2018-07-18" version="1">MNIKKISTAVALAFAVCTVASAGPVILESGNLKFTVANYDSAAVGYGNTAGLVCTTAATCATAGGAVPGGVAGESSWGIFSISSISEISTGTTIWSAGAGQYLTGMFGGLQDYEVQVTNSITGPSTTILDSGGWLNMYMNSTNYTPADGPGGRTGQYAYTGITGGTLMLSADFSPGILGGIPAATYTSTYQDASIGGTGEGYMDVTGGAWASQLATDSLTDPNGGNHDLYLGTQFAANATATADGWTVISASQVFGAAPEPASLALFGLGLAGLAFLRRRRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTB9</accession>
    <name>A0A2S9GTB9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Exosortase A system-associated hydrolase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4339</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000032">
        <property type="protein sequence ID" value="PRC90938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90938">
        <property type="protein sequence ID" value="PRC90938"/>
        <property type="gene ID" value="S2091_4339"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017531">
        <property type="entry name" value="Hydrolase-1_PEP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022742">
        <property type="entry name" value="Hydrolase_4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12146">
        <property type="entry name" value="Hydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03100">
        <property type="entry name" value="hydr1_PEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hydrolase_4" evidence="1">
        <location>
            <begin position="47"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="276" mass="30839" checksum="7BAA680833BE6373" modified="2018-07-18" version="1">MHYEEMALSFTCQSQQLVGVLSQPEQAGQSGVLIIVGGPQYRAGSHRQFTLLARQLAARGIPVMRFDYRGMGDSTGEPINFDNIDADLSAALDYFCAIAPSIQSIVLWGLCDGATAAALYAQHDPRISGIVMLNPWIRTEQGLAKAYLKHYYPKRLLQADFWKKVFGGKFNVLHAATSLFQQLKPAHQKETAQLELPERMLAGLQNFNGRVLLILSGQDLTAKEFTEVSSTSPQWKKFLKQPQVCQHELAAADHTFSRRAWRDQVAGWTAAWLMEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTH3</accession>
    <name>A0A2S9GTH3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_4309</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000031">
        <property type="protein sequence ID" value="PRC91013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91013">
        <property type="protein sequence ID" value="PRC91013"/>
        <property type="gene ID" value="S2091_4309"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002549">
        <property type="entry name" value="AI-2E-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21716">
        <property type="entry name" value="PTHR21716"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01594">
        <property type="entry name" value="AI-2E_transport"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="65"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="158"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="218"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="245"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="278"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="310"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC91013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="359" mass="39116" checksum="44A8A8CCAAD2F62B" modified="2018-07-18" version="1">MTITKEQFQTAIWVLLGIALVLLLFMLGPVLMPFVTGAILAYILNPLVDRLCRCTIGKRSLARSMAVLIAMVALIASILALALIVLPVVQNEIPLLQEQIPRFLDQMDAMFAPKLLDYGIHVKLDSAGIKQMLSEQLAGSGQKVTSGILESLKVGGTAVIGLVANVLLIPMVLYYLLLDWHAILNRMHLFIPRRWVNKTTDLVQETDDLLAQYLRGQLLVMFILAVYYSSALALAGFSVALPVGILTGLLVFIPYIGFGFGLCLALIGAVLQLDPLHGLLMVAIIYGIGQVVEGFYLTPRLVGERIGLPPLAVIFALLAFGQLFGFIGILLALPASAITSVALKHLRALYYRSRFYTAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTX1</accession>
    <name>A0A2S9GTX1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4152</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000028">
        <property type="protein sequence ID" value="PRC91151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91151">
        <property type="protein sequence ID" value="PRC91151"/>
        <property type="gene ID" value="S2091_4152"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="74"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="98"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="136" mass="15995" checksum="8341C33A7780ACDF" modified="2018-07-18" version="1">MNEVSLFRLYVLRALYLFVVIGLGMLVVPQIFTHTKPWEFFHGVTTCMLVAFWLLCILGLRYPLQLLPILMWELIWKTVWLILIPLPLWLSGTLDDSLIPNVINVSCVVLVYIAMPWSYVYNHYVKNQSNPWRNVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GU19</accession>
    <name>A0A2S9GU19_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">MGT: glycosyltransferase, MGT family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4157</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000028">
        <property type="protein sequence ID" value="PRC91156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91156">
        <property type="protein sequence ID" value="PRC91156"/>
        <property type="gene ID" value="S2091_4157"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016758">
        <property type="term" value="F:hexosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008194">
        <property type="term" value="F:UDP-glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03784">
        <property type="entry name" value="GT1_Gtf-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002213">
        <property type="entry name" value="UDP_glucos_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006326">
        <property type="entry name" value="UDPGT_MGT-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00201">
        <property type="entry name" value="UDPGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01426">
        <property type="entry name" value="MGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="425" mass="48288" checksum="B528DC29DA63233F" modified="2018-07-18" version="1">MTEKTIALFPEASYGAALNCLGIAQELLKQGARPVFICHPGFHGVFAEYGFPEYRLFTEQESDDAGNIDWTKFVQQHREAFRTSAFEQIDSYIAPTWEAVVASVIRIEVPLRQLLSRLKPAAIVVDNVIAFPAVINSGIPWVRVVSCAETEITDPDIPPYLSGCASKDRADWEQFSEHYASAIAPIHERYMTFLRSCDLAPFQNDEFMETSPWLNLLLAPKILRHQRQNPLMPDKFIFLEGCVRTEVPWHAPRFASHNDKPLVYTSFGSLGAMDIELFERMIQVFATLPYRFIINVGSWREHYQTTPDNVYLDSWFPQPSVVRETQLFIHHGGNNSFCEALYFGVPSLIMPYCWDGHDNAQRAQETGVGKHLPRYEWSDEQLRATITALIDDQAMHKRLQLNAKHMQASNGAQVAAAAILHAIKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUB0</accession>
    <name>A0A2S9GUB0_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Cyanophycin synthetase</fullName>
            <ecNumber evidence="7">6.3.2.29</ecNumber>
            <ecNumber evidence="6">6.3.2.30</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Cyanophycin synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">S2091_4031</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the ATP-dependent polymerization of arginine and aspartate to multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[L-4-(L-arginin-2-N-yl)aspartate](n) + ATP + L-aspartate = [L-4-(L-arginin-2-N-yl)aspartate](n)-L-aspartate + ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13277"/>
            <dbReference type="Rhea" id="RHEA-COMP:13728"/>
            <dbReference type="Rhea" id="RHEA-COMP:13733"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:137986"/>
            <dbReference type="ChEBI" id="CHEBI:137990"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.29"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>[L-4-(L-arginin-2-N-yl)aspartate](n)-L-aspartate + ATP + L-arginine = [L-4-(L-arginin-2-N-yl)aspartate](n+1) + ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:23888"/>
            <dbReference type="Rhea" id="RHEA-COMP:13732"/>
            <dbReference type="Rhea" id="RHEA-COMP:13733"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32682"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:137986"/>
            <dbReference type="ChEBI" id="CHEBI:137990"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.30"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">In the C-terminal section; belongs to the MurCDEF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.29" evidence="7"/>
    <dbReference type="EC" id="6.3.2.30" evidence="6"/>
    <dbReference type="EMBL" id="PUGF01000026">
        <property type="protein sequence ID" value="PRC91246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91246">
        <property type="protein sequence ID" value="PRC91246"/>
        <property type="gene ID" value="S2091_4031"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071161">
        <property type="term" value="F:cyanophycin synthetase activity (L-arginine-adding)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071160">
        <property type="term" value="F:cyanophycin synthetase activity (L-aspartate-adding)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004326">
        <property type="term" value="F:tetrahydrofolylpolyglutamate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009059">
        <property type="term" value="P:macromolecule biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005479">
        <property type="entry name" value="CbamoylP_synth_lsu-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011810">
        <property type="entry name" value="Cya_phycin_syn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044019">
        <property type="entry name" value="Cyanophycin_syn_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018109">
        <property type="entry name" value="Folylpolyglutamate_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036565">
        <property type="entry name" value="Mur-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004101">
        <property type="entry name" value="Mur_ligase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036615">
        <property type="entry name" value="Mur_ligase_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013221">
        <property type="entry name" value="Mur_ligase_cen"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02786">
        <property type="entry name" value="CPSase_L_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18921">
        <property type="entry name" value="Cyanophycin_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02875">
        <property type="entry name" value="Mur_ligase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08245">
        <property type="entry name" value="Mur_ligase_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53244">
        <property type="entry name" value="SSF53244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53623">
        <property type="entry name" value="SSF53623"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02068">
        <property type="entry name" value="cya_phycin_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01011">
        <property type="entry name" value="FOLYLPOLYGLU_SYNT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-grasp" evidence="11">
        <location>
            <begin position="209"/>
            <end position="462"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00003184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00013005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00031353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PRC91246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="856" mass="91630" checksum="F3F7D3A79427EF23" modified="2018-07-18" version="1">MEVSRIRALRGPNLWSHHTAIEAIVTCSPDELNIINLPDFETRLRARFPDLSSLQPTGYHDAIPIAHVYEHVALGLQASAGCPVTFSRTTQTMEPGVFQVVVEYTEEAVGRLAFELADKLCIAALQDSFFDLDSALSDLRELDEDVRLGPSTGSIVHAAVARNIPYRRLTDGSLVMFGWGSKQRRIQAAEMDCTSAIAEAIAQDKELTKKLLNAAGVPVPLGRTVVDTDDGWKVACEIGLPVVVKPKDGNQGKGVTVNITTREQLDAAFLAASEFRDDILVERYLPGSDFRLLVIGNKLIAAARRDPPQVVGDGVKTVKQLVDHVNLDPKRGSGHATSLTKIRIDDIALASLSSQGFNAESIPPKGRRVNLRNNANLSTGGSATDVTDDVHPEVAARAVAAAQMVGLDICGVDLVCDSVLKPIEEQHGGIVEVNAAPGLRMHISPSFGKGRQVGEAIVATMFEEGNDGRIPVVAVTGTNGKTTTVRLIAHLLTASGLRTGMTNTDGVYIEGQRIDSGDCSGPRSARNVLLHPDVDAAVFETARGGVLREGLAFDRCQVAVITNIGTGDHLGLNYITSLEDLAVLKRVIVQNVADNGVAVLNAADPIVASMANNCLGKVTFFAADSHEAIMATHRAQGNRVVYVEDGMLVAAEGEFKHKIALSNVPITHGGNIAFQVENVMASVAAAWGVGISWQSIEVGLKTFANDTDNAPGRFNLFNYRGATLIADYGHNPDAIVALVNAVETMPAKRRSVVISGAGDRRDQDIRQQTEILGAAFDDVILYQDQCQRGRADGEVVALLRAGLKNAKRTKQISEIQGEFIAIDTALANLTEGDLCLILVDQVEEALAHISQRIQQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUF0</accession>
    <name>A0A2S9GUF0_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 8">3-dehydroquinate dehydratase</fullName>
            <shortName evidence="8">3-dehydroquinase</shortName>
            <ecNumber evidence="6 8">4.2.1.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Type II DHQase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">aroQ</name>
        <name evidence="12" type="ORF">S2091_3907</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 8">Catalyzes a trans-dehydration via an enolate intermediate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>3-dehydroquinate = 3-dehydroshikimate + H2O</text>
            <dbReference type="Rhea" id="RHEA:21096"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16630"/>
            <dbReference type="ChEBI" id="CHEBI:32364"/>
            <dbReference type="EC" id="4.2.1.10"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 8">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 3/7.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5 8">Homododecamer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 8">Belongs to the type-II 3-dehydroquinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.10" evidence="6 8"/>
    <dbReference type="EMBL" id="PUGF01000024">
        <property type="protein sequence ID" value="PRC91362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91362">
        <property type="protein sequence ID" value="PRC91362"/>
        <property type="gene ID" value="S2091_3907"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00053">
        <property type="reaction ID" value="UER00086"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003855">
        <property type="term" value="F:3-dehydroquinate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:cellular amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009423">
        <property type="term" value="P:chorismate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00466">
        <property type="entry name" value="DHQase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.9100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00169">
        <property type="entry name" value="AroQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001874">
        <property type="entry name" value="DHquinase_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018509">
        <property type="entry name" value="DHquinase_II_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036441">
        <property type="entry name" value="DHquinase_II_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21272">
        <property type="entry name" value="PTHR21272"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01220">
        <property type="entry name" value="DHquinase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001399">
        <property type="entry name" value="DHquinase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52304">
        <property type="entry name" value="SSF52304"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01088">
        <property type="entry name" value="aroQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01029">
        <property type="entry name" value="DEHYDROQUINASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="7 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="8 10">
        <location>
            <begin position="103"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8 9">
        <location>
            <position position="24"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="8 9">
        <location>
            <position position="102"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8 10">
        <location>
            <position position="76"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 10">
        <location>
            <position position="82"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 10">
        <location>
            <position position="89"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 10">
        <location>
            <position position="113"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="8 11">
        <location>
            <position position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR001399-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR001399-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR001399-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PRC91362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="145" mass="15557" checksum="B09BE2C7621544DB" modified="2018-07-18" version="1">MAKNLLLLNGPNLNLLGTREPQVYGITTLQELEQAATAQALAAGAQLSCLQSNHEGVLIDRIHAAKQQNVDAIIINPGGLTHTSVALRDALAGVAIPFIEVHISNVHQREAFRHHSFLSEIAQGVICGLGVDGYRLAIDFALQKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUM0</accession>
    <name>A0A2S9GUM0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">BON domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3842</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000023">
        <property type="protein sequence ID" value="PRC91427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91427">
        <property type="protein sequence ID" value="PRC91427"/>
        <property type="gene ID" value="S2091_3842"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007055">
        <property type="entry name" value="BON_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04972">
        <property type="entry name" value="BON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50914">
        <property type="entry name" value="BON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015667004" evidence="1">
        <location>
            <begin position="25"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="domain" description="BON" evidence="2">
        <location>
            <begin position="37"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="107" mass="11663" checksum="514171C673DEA4B7" modified="2018-07-18" version="1">MKPKFGTMCVLVGSLLTITAVAYADDVDQHHPMTFIKDSAITSLIKTKLAAEHLSTLKNIKVDTDDKGVVWLSGYAPSQMLVDKSESIARNTDGVRAVKNNIVVKMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUN9</accession>
    <name>A0A2S9GUN9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Polyphosphate:nucleotide phosphotransferase, PPK2 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_3844</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000023">
        <property type="protein sequence ID" value="PRC91429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91429">
        <property type="protein sequence ID" value="PRC91429"/>
        <property type="gene ID" value="S2091_3844"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008976">
        <property type="term" value="F:polyphosphate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006797">
        <property type="term" value="P:polyphosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016898">
        <property type="entry name" value="Polyphosphate_phosphotransfera"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022300">
        <property type="entry name" value="PPK2-rel_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022488">
        <property type="entry name" value="PPK2-related"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03976">
        <property type="entry name" value="PPK2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028756">
        <property type="entry name" value="PPK2_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03709">
        <property type="entry name" value="PPK2_rel_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PPK2" evidence="4">
        <location>
            <begin position="31"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC91429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="289" mass="33953" checksum="B3C539CCD9D591FB" modified="2018-07-18" version="1">MKINSKDFRVSEGDKVSLQKWPTKVDAVYQTKKQYQQLLHEHVAQLSALQQLLYASNQHAILLIFQAMDAAGKDGAIRHVMSGVNPQGCQVFSYKHPSAEELQHDFLWRTTRDLPERGRIGIFNRSYYEEVLIVRVHPELLHSEGLPDKQSDDQSIWHNRYLSITNLEKHLHSNGTRIIKFFLHLSKGEQKRRFLERIDEPEKNWKFSLADITERKFWKQYMTAYEECLSATSTKNSPWYVVPADDKENARLIVSRIVLDTLEELKMTYPETTPERKKELLSIRKQIEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUV0</accession>
    <name>A0A2S9GUV0_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Flagellar secretion chaperone FliS</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_3768</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Cytoplasm</location>
            <location evidence="1 6">Cytosol</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the FliS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000022">
        <property type="protein sequence ID" value="PRC91490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91490">
        <property type="protein sequence ID" value="PRC91490"/>
        <property type="gene ID" value="S2091_3768"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044780">
        <property type="term" value="P:bacterial-type flagellum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16098">
        <property type="entry name" value="FliS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003713">
        <property type="entry name" value="FliS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036584">
        <property type="entry name" value="FliS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34773">
        <property type="entry name" value="PTHR34773"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02561">
        <property type="entry name" value="FliS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039090">
        <property type="entry name" value="Flis"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101116">
        <property type="entry name" value="SSF101116"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00208">
        <property type="entry name" value="fliS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-1005">Bacterial flagellum biogenesis</keyword>
    <keyword evidence="7" id="KW-0966">Cell projection</keyword>
    <keyword evidence="5" id="KW-0143">Chaperone</keyword>
    <keyword evidence="7" id="KW-0969">Cilium</keyword>
    <keyword evidence="3 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0282">Flagellum</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR039090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC91490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="156" mass="17030" checksum="FC09BAD2DC867E6B" modified="2018-07-18" version="1">MFGYSPRNAANAYSKVSMETGVIAADPHKLIMLLFDGAIMAIYNAIQQIEAGKIPEKGRSITHAISIVESGLRASLNKDVGGELAKNLDALYSYMAKQLFMANLKNDTKRLLEVKTLLNDLRGAWEQIAPVKAKQAEYVGTPKDALAPRKSSHIVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GV11</accession>
    <name>A0A2S9GV11_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fusaric acid resistance protein family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3675</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000021">
        <property type="protein sequence ID" value="PRC91559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91559">
        <property type="protein sequence ID" value="PRC91559"/>
        <property type="gene ID" value="S2091_3675"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006726">
        <property type="entry name" value="PHBA_efflux_AaeB/fusaric-R"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04632">
        <property type="entry name" value="FUSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="71"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="97"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="123"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="151"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="381"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="406"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="433"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="459"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="488"/>
            <end position="508"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="709" mass="77737" checksum="F3D04CDEB6E003EC" modified="2018-07-18" version="1">MIFSPFTASYWRDLFRNEFVPFPGRSTAVLRYVLISALVIVISMTLQVPSLALSLIMVFFTAQENTVLTRLSGIVLAVGATLAVILSMLLLKMTMDYPVLRIFGAALIGFCGMYFMRISKLGTIGYLVALFVINLQSLVDVSNDPEVVTRALLWVWVAIAYPIVLTITVNYLMLPAKPAQLLAGELHRQLNVVLSQLNAGKVLPAPAPLGLDLIERGVLTLHRHLVFATMGDNHYLLNKSRYLIRINTVDRLHTAAVKLSRLSPCNSSDSSFNQPDLLAALLARCAELQHQFSHETAVSIAAIPISEEKNDDPRIAILHEMAHALNTLAEAEQAPILSATPDKEPQIAADALSNPVYAQFALKTMLATFFCYAFYTAVQWPGIQTSMLTCLIMALPSLGASSHKGLLRVVGCAMGSVAALLATVYVVPHLDGIVGLLMLTLPVIAVGAWIAAGSARISYIGAQLVFAYALALFGQFEPSTNLPEIRDRMIGILLGIGVSITVYSALWPESEQGELKKMLARLLRSIATVARLDQSTQNDITQLRTLDQARLKSWSLLAQNREIQARVALEPGWQYAHDSVTVKMQTWLAQVQEALFAVNWLQTQLAHSERSLSADIDIWSELNSFKASAALQLENMSDMFNEEGTTQPSLQQSFAKFKQEYALISAHEAALSQASNVLSAVHATYESIIQLGNTLPLSQPMQPEQPVRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GV13</accession>
    <name>A0A2S9GV13_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Putative Fis-like DNA-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_3688</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the transcriptional regulatory Fis family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000021">
        <property type="protein sequence ID" value="PRC91572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91572">
        <property type="protein sequence ID" value="PRC91572"/>
        <property type="gene ID" value="S2091_3688"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005412">
        <property type="entry name" value="Fis_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002197">
        <property type="entry name" value="HTH_Fis"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02954">
        <property type="entry name" value="HTH_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002097">
        <property type="entry name" value="DNA-binding_Fis"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01590">
        <property type="entry name" value="HTHFIS"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH_8" evidence="3">
        <location>
            <begin position="37"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00029540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC91572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="77" mass="8767" checksum="3895BE48CACFCAD1" modified="2018-07-18" version="1">MSKDNIQDAVSKNLEKYFRDLGEQPASNIYDMVVLAVEKPMLEMVMTRAESNQSQAADMLGINRNTLRKKLQQHGLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GV30</accession>
    <name>A0A2S9GV30_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein conserved in bacteria containing a divergent form of TPR repeat</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3794</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000022">
        <property type="protein sequence ID" value="PRC91516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91516">
        <property type="protein sequence ID" value="PRC91516"/>
        <property type="gene ID" value="S2091_3794"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014562">
        <property type="entry name" value="UCP030959_TPR_rpt-cont"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF030959">
        <property type="entry name" value="UCP030959"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="30"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="253" mass="28507" checksum="371274A8B5615AAF" modified="2018-07-18" version="1">MPFLGLGLHIFVAIFFAIHAIRSGRELYWLLILFMFPLFGSVVYFFAIFLPSLKSNTHVQLGLRKVTTAAVNSIDPGRELRDAKAAYEFTPTAQNQWRYADALLAADQVADAVQQFEICLQGPFAKDLEIQFAAANAQLRFQQPEKALNLLLAIRESSITFRTEAVTLLLAKIYAMQGNKVAAKQEFEQVVTQFGSVEARAEYAIWAAQNGDMNTAQHLRAELNDLKKHWNKNSRAQYQPLLVKLESVLQGQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GV59</accession>
    <name>A0A2S9GV59_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HDOD domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3704</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000021">
        <property type="protein sequence ID" value="PRC91588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91588">
        <property type="protein sequence ID" value="PRC91588"/>
        <property type="gene ID" value="S2091_3704"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013976">
        <property type="entry name" value="HDOD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08668">
        <property type="entry name" value="HDOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51833">
        <property type="entry name" value="HDOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HDOD" evidence="1">
        <location>
            <begin position="122"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="375" mass="41734" checksum="0C463EC160765736" modified="2018-07-18" version="1">MGNLISRLFKIFKSGYVPKDSQFAPIQTNSPLVLKEDPSVVSSTTVDNTVNTLASEENKKADSVIEYDGDYKDLPDFVDRCYFDWMAGKASENSSTDESFERKIIEYLDVLAESEFAGANLIPRVPSVMVQLLKRTHEENVTGSELSRIIAKDVVLVAAILNEVNSSFYNMNDKVTELSQAILLLGHNRLRMVLAKISFTPVFNDQLGTYSKLTSSKLWEESQQRAIACYLLAKHQNIDPFMAFLAGLMQDVGIIVALRIFDRSSNNSDFPTATEFRAAFQKKSLILSARIGQIWTLPEIVTKAIDAQLMESTELAALPMGVVLKKADFISKTCILINTGQLNVDMEQVKDILIESEMDCLLSMQGGQISLANIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GV78</accession>
    <name>A0A2S9GV78_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="12">ABC-type transport system involved in Fe-S cluster assembly permease and ATPase component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">S2091_3743</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000021">
        <property type="protein sequence ID" value="PRC91627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91627">
        <property type="protein sequence ID" value="PRC91627"/>
        <property type="gene ID" value="S2091_3743"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="PTHR24221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="SSF90123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-1278">Translocase</keyword>
    <keyword evidence="2 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="26"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="59"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="140"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="172"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="265"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="11">
        <location>
            <begin position="28"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="354"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="387"/>
            <end position="394"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PRC91627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="605" mass="67176" checksum="329E8DD036A0AC30" modified="2018-07-18" version="1">MPSSTRNDWATIKTLLPYLWAYKWRVCIALVCLVTAKMSLVAVPIVLKKLIDSLNPLTPGHATTTALALPLGILLAYGLLRLSTSLFTELREFVFARVTQRAVRTIALQVFRHLHGLSLRFHLNRQTGGMTRDIERGTRAVSSLVSFALFSIFPTLIEIGMVLGYLVLHYDIWISIITFCALILYITFTISVTEWRTHFRRTMNELDSKANTKAIDSIINYETVKYFGNEEMEAQRYDHGLQNYENAAVKSQTSLSLLNVGQSMIIALAVSLILWRATVGVIAGQMTLGDLVLVNSFMLQLYVPLNFLGVLYREIKQSLADMEKLFSLLDQHREIADADSATPLQVGNHAGPEIRFNQVDFSYESNRQILHQVSFVMPAGVTTAVVGASGSGKSTLARLLFRFYDIQHGSIRIAGQEIRDITQASLRASIGIVPQDTVLFNDTIEYNIAYGKPGASHAEIVAAAQAAYIHDFIQSLPDGYATMVGERGLKLSGGEKQRVAIARTVLKNPAILIFDEATSALDSKSEQAIQTQLKEIAKGRTSLVIAHRLSTIADAAQIIVMEHGRIVESGTHAELLEKDHVYAQMWARQQAHPELELWSESAETV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GV93</accession>
    <name>A0A2S9GV93_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Poly(R)-hydroxyalkanoic acid synthase, class I</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_3577</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000020">
        <property type="protein sequence ID" value="PRC91639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91639">
        <property type="protein sequence ID" value="PRC91639"/>
        <property type="gene ID" value="S2091_3577"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042619">
        <property type="term" value="P:poly-hydroxybutyrate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010963">
        <property type="entry name" value="PHA_synth_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010941">
        <property type="entry name" value="PhaC_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07167">
        <property type="entry name" value="PhaC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01838">
        <property type="entry name" value="PHA_synth_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PhaC_N" evidence="5">
        <location>
            <begin position="114"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC91639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="604" mass="66650" checksum="772E7FA7501007D5" modified="2018-07-18" version="1">MKSFDPEALVAAMLTQLNTQPQWQAWTAAYHTMPNMSPFFNPPAAISSTPAPVFPSTFMPATAMPDMSKQVSTLLKDLGGNLDPQVVNQLQQEYFEKISTLWQDMLQSKAAVLDDRRFKSPEWHNSSLHAYSAASYLLNARYLTALAEAVQAPKRAKQKILFAVGQIVDAMSPANFLATNPEAQGKLIASHGESLTKGMSNMLADMQKGRISQTDETAFEVGHNVATTEGQVVFENHLFQLIQYKPLSGTVHQRPLLMVPPCINKYYILDLQPENSLVRYALEQGHSVFLVSWVNPDAELGTITWDDYVEAGVIEAIHVVQAISGQDKINTFGFCVGGTLLSTSLAVLAARGEQAAASVTLLTTLLDFEDAGILEVFVDEMQVEMRETSIGQGGLMSGRDLGSAFSSLRPNDLVWNYVQANYLKGEEPTAFDLLYWNGDGTNLPGPMFCWYLRNTYLENNLKQANRLIVAGEKVDLGKIDAPVFVYGSREDHIVPWTAAFASLSLLNPKKPSKNRFVLGASGHIAGVINPPAKMKRNYWSNNKSTKNSQEWMDGAQLHAGSWWPEWSEFLAEHAGKKIKATAKMGNAKHKVIEPAPGRYVKVSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVA4</accession>
    <name>A0A2S9GVA4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3578</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000020">
        <property type="protein sequence ID" value="PRC91640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91640">
        <property type="protein sequence ID" value="PRC91640"/>
        <property type="gene ID" value="S2091_3578"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="22"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="52"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="80" mass="9227" checksum="367C5BF599DA0579" modified="2018-07-18" version="1">MHIIALGWIYVVLMMAITESSIIAGIMTFTFYCAIPLGLVWYLTSRKKPKIDKSQEQHNSDLKRQQHDSSKPCEKLETKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVB4</accession>
    <name>A0A2S9GVB4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycine/D-amino acid oxidases (Deaminating)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3592</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000020">
        <property type="protein sequence ID" value="PRC91654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91654">
        <property type="protein sequence ID" value="PRC91654"/>
        <property type="gene ID" value="S2091_3592"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DAO" evidence="1">
        <location>
            <begin position="2"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="416" mass="45717" checksum="EDD696285CCB9AB6" modified="2018-07-18" version="1">MRVAVIGAGVVGVTTAYFLAQNGHQVSVIEQRGNVSEEASLGHAGLLGAAHLTPFAAPGMPKQILSHFFKTDGAINLRPSVNVTHWRWLRSWLRECSLEGLLANKEKMQRLGRYSQQLLSELSHSHNLDFQQRSGILQLFRNVKEQKKIIAGLALLSDADLPFQQLDTAACHQLEPALNKDTSLAGGLYLPQDGNGNCVLFTKQLKLVAQQLGVEFEFLTKCEQIIPNKNGATLHLKKAEQTGQQQFDAVVLASGASSTPFLKNIGINLRIAQFQSYSNTANIKNLDDSPRLSIIDESEQIAITRMDKRIRIAGTLHLGKRKNTADERAWQKLRNVGTDWFPDAANYHTGQNWSGHHLMLSDSTPVLGRSAVKNIFVNCAHAEYGWAMATGSGKILADLISGKSPEIDLDGLTVLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVG6</accession>
    <name>A0A2S9GVG6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Bcct: transporter, betaine/carnitine/choline transporter (BCCT) family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_3651</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000020">
        <property type="protein sequence ID" value="PRC91713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91713">
        <property type="protein sequence ID" value="PRC91713"/>
        <property type="gene ID" value="S2091_3651"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071705">
        <property type="term" value="P:nitrogen compound transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018093">
        <property type="entry name" value="BCCT_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000060">
        <property type="entry name" value="BCCT_transptr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30047">
        <property type="entry name" value="PTHR30047"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02028">
        <property type="entry name" value="BCCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00842">
        <property type="entry name" value="bcct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01303">
        <property type="entry name" value="BCCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="54"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="93"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="143"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="194"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="235"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="265"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="318"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="350"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="405"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="452"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="477"/>
            <end position="497"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC91713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="511" mass="56380" checksum="208B567F9659C2C9" modified="2018-07-18" version="1">MTEPLSIPTKDRLNSTVFIGSAACIIALTIWSIIDTQHVAAIMRLVLGWITEGFGWYYFLVATLCIVFVIFIASSKFGNIKLGPDNSKPEYNLFTWGAMLFAAGIGIDLMFFSVAEPVTHLLAPPEGEANTIAAARQAMSWTLFHYGITGWSMYALMGMALGYFSYRYDLPLSIRSALYPILGKRIHGALGHGVDIAAVLGTIFGIATSLGIGVVQLNYGLKFMFDVPEGIVPQAWLILLSVVMATISVVLGVDKGIRRLSELNVILAIFLIIFVLISGKTVFLLNGLVLNIGDYLHSFTSMTLNTFAFDRPVDWLNAWTLFFWAWWVAWAPFVGLFLARISRGRTLRQFIAGTLIIPFVFTLIWISVFGNSALDIVLSGNQEFGKIAMETPERAFYSLLAEYPWIGFSSILATVTGLLFYVTSADSGALVLGNFTSYLKTANSDAPKWLRIFWSFAIGILTLSMLMVGGVPTLQNATIIMGLPLSFVMLFIMIGLYKALRIEAINEENKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVM6</accession>
    <name>A0A2S9GVM6_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">CDP-diacylglycerol--serine O-phosphatidyltransferase</fullName>
            <ecNumber evidence="4">2.7.8.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Phosphatidylserine synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_3644</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a CDP-1,2-diacyl-sn-glycerol + L-serine = a 1,2-diacyl-sn-glycero-3-phospho-L-serine + CMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16913"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:57262"/>
            <dbReference type="ChEBI" id="CHEBI:58332"/>
            <dbReference type="ChEBI" id="CHEBI:60377"/>
            <dbReference type="EC" id="2.7.8.8"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the CDP-alcohol phosphatidyltransferase class-I family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.8" evidence="4"/>
    <dbReference type="EMBL" id="PUGF01000020">
        <property type="protein sequence ID" value="PRC91706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91706">
        <property type="protein sequence ID" value="PRC91706"/>
        <property type="gene ID" value="S2091_3644"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003882">
        <property type="term" value="F:CDP-diacylglycerol-serine O-phosphatidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004533">
        <property type="entry name" value="CDP-diaglyc--ser_O-PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000462">
        <property type="entry name" value="CDP-OH_P_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043130">
        <property type="entry name" value="CDP-OH_PTrfase_TM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01066">
        <property type="entry name" value="CDP-OH_P_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00473">
        <property type="entry name" value="pssA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00379">
        <property type="entry name" value="CDP_ALCOHOL_P_TRANSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="42"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="131"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="161"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="193"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="224"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="248"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00032361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC91706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="285" mass="31654" checksum="442F38AD8959309D" modified="2018-07-18" version="1">MAFQRRKSKATLKNFFKIVKKNQNAATPAGAEVVRKKPRRGIYLLPNAFTTAALFCGFYAIVMGMDGFFEKATIAIFIAMVLDSLDGRVARLTNTQSEFGAQYDSLSDMVSFGAAPALVAYEWGLRGLGQWGWLAAFVYCACAALRLARFNTNIAVVDKRYFQGIPSPAAAALVAGFIWAMTDLNIAGPDMRWVIWSITVLAGLTMVSNVPFYSFKDVNLKKSVPFAVPLVLVLVYVLVVSYPPMVLFGVFVLYCLSGYAIFLWRWRKGRPVSILQTELEVHDDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVN5</accession>
    <name>A0A2S9GVN5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3654</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000020">
        <property type="protein sequence ID" value="PRC91716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91716">
        <property type="protein sequence ID" value="PRC91716"/>
        <property type="gene ID" value="S2091_3654"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008517">
        <property type="entry name" value="DUF799"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05643">
        <property type="entry name" value="DUF799"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015473158" evidence="1">
        <location>
            <begin position="25"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="221" mass="23015" checksum="DE60991D0EB51379" modified="2018-07-18" version="1">MLKKTLKLVACLMLIALATGCANHQVTPTDYTAFKQSRPASILILPPLNESPDVAATYSMLSQMTYPLSEAGYYVLPVTLVDETFKQNGLSTPADIHAVAPAKLKEIFGADAALYVTVTQYGASYTVLNSVVIVTAKAKLVDLKTGTTLWQGAATASNNEGGNNGGGGLIGALVAAAVKQVINNVSDAGHPVAGAASMRLLSAGRANGILYGPRSERYQTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVP8</accession>
    <name>A0A2S9GVP8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Dipeptidyl aminopeptidase/acylaminoacyl-peptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3554</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000019">
        <property type="protein sequence ID" value="PRC91799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91799">
        <property type="protein sequence ID" value="PRC91799"/>
        <property type="gene ID" value="S2091_3554"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_S9" evidence="2">
        <location>
            <begin position="470"/>
            <end position="669"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="669" mass="71485" checksum="FA8F110D2A6B2A1E" modified="2018-07-18" version="1">MPINHFSNVQSMKIIHLPSLKLAIVLGAAIGSVNAAVLTPSSASTSLPLHHYLSVHMSPNQQLIASIEGDSSLSGGAPTIRDLIIRSADGKNISTVKLPCGRVKQCWPESPAWTPDSGKISFALRTPGSHARSLYQVNADGSNLKKLLAFNGTISDLLYSPTGQLAMLATENATKELGAVEAGAPITGDMDAAPPEQRIAVLNKNELQWASPATMFVYEYDWIPDGSGFVGTAAQGDGDKNWWIAQLYTFRAEQAQLLYSPANHQQQLANPVVSRDGKSVAFIAGIMSDFGSTGGDIYTIPVAGGTALNVTPKLPSSATSIAWSCNGNLLANVLAGDQTQLVDFGNGITTNGGTVLWHGQESLHGEQTKHTDTCTSGITAQVHESFTQAPEIAVGEIGKWHNITHANERNISSYSVQSLSWKSDNFTVQGWLILPDNLASGKKLPMITIVHGGPAAAVRPGFIETGLTRSLLDKGYALFLPNPRGSFGQGEQFAASNVRDFGYGDLRDVMAGVDAAIAAAPIDPQRLGIMGHSYGGFMTMWAVTQTNRFKAAVAGAGISNWQSYYGENGIDEWLIPYFGASVYDDPEVYAKSSPINFIRQVRTPTLSLVGAADLECPAPQTQEFGHALKALGIPSSTIIYPGEGHAFREPATLVDREKRTLAWFAQYLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GW12</accession>
    <name>A0A2S9GW12_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin)</fullName>
            <ecNumber evidence="6">1.17.7.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ispG</name>
        <name evidence="7" type="ORF">S2091_3471</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>(2E)-4-hydroxy-3-methylbut-2-enyl diphosphate + 2 H(+) + H2O + oxidized [flavodoxin] = 2-C-methyl-D-erythritol 2,4-cyclic diphosphate + reduced [flavodoxin]</text>
            <dbReference type="Rhea" id="RHEA:43604"/>
            <dbReference type="Rhea" id="RHEA-COMP:10622"/>
            <dbReference type="Rhea" id="RHEA-COMP:10623"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57618"/>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
            <dbReference type="ChEBI" id="CHEBI:58483"/>
            <dbReference type="ChEBI" id="CHEBI:128753"/>
            <dbReference type="EC" id="1.17.7.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="6">Binds 1 [4Fe-4S] cluster.</text>
    </comment>
    <comment type="pathway">
        <text evidence="6">Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via DXP pathway; isopentenyl diphosphate from 1-deoxy-D-xylulose 5-phosphate: step 5/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the IspG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.17.7.3" evidence="6"/>
    <dbReference type="EMBL" id="PUGF01000018">
        <property type="protein sequence ID" value="PRC91915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91915">
        <property type="protein sequence ID" value="PRC91915"/>
        <property type="gene ID" value="S2091_3471"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00056">
        <property type="reaction ID" value="UER00096"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046429">
        <property type="term" value="F:4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019288">
        <property type="term" value="P:isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016114">
        <property type="term" value="P:terpenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.413.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00159">
        <property type="entry name" value="IspG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011005">
        <property type="entry name" value="Dihydropteroate_synth-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016425">
        <property type="entry name" value="IspG_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004588">
        <property type="entry name" value="IspG_bac-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045854">
        <property type="entry name" value="NO2/SO3_Rdtase_4Fe4S_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30454">
        <property type="entry name" value="PTHR30454"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04551">
        <property type="entry name" value="GcpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004640">
        <property type="entry name" value="IspG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00612">
        <property type="entry name" value="ispG_gcpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="3 6" id="KW-0408">Iron</keyword>
    <keyword evidence="4 6" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5 6" id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="6">
        <location>
            <position position="313"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="316"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="359"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="366"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC91915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="419" mass="45029" checksum="45096F09C3EC4AA6" modified="2018-07-18" version="1">MIQNNESSPILSGAIKRRTSRSVIIAHGDRQVIVGGDAPIVIQSMTNTDTVDAIGTAIQIKELARAGSELVRITVNTQEAAAAVASIREQLDRMGVDVPLVGDFHYNGHTLLKEFPDCAQALSKYRINPGNVGQGAKRDSQFAQMIEIAARYNKPVRIGVNWGSLDQGLLARIMDENAQRNSPWSAQSVMYEALIVSALENAQRAEQVGLAGDKIILSCKVSGVQDLIAVYRELARRCDYPLHLGLTEAGMGSKGIVASTAALSVLLQEGIGDTIRISLTPEPGGDRCKEVIVGQEILQTMGLRKFTPMVIACPGCGRTTSTVFQELADDIQTYLREQMPVWKTQFAGVEAMNVAVMGCIVNGPGESKHANIGISLPGTGESPAAPVFVDGVKTVTLRGENIAKEFQQIVLTYVQSHYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GW97</accession>
    <name>A0A2S9GW97_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Betaine aldehyde dehydrogenase</fullName>
            <shortName evidence="4">BADH</shortName>
            <ecNumber evidence="4">1.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">betB</name>
        <name evidence="9" type="ORF">S2091_3334</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the irreversible oxidation of betaine aldehyde to the corresponding acid.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>betaine aldehyde + H2O + NAD(+) = glycine betaine + 2 H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:15305"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15710"/>
            <dbReference type="ChEBI" id="CHEBI:17750"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.2.1.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
        <text evidence="4">Binds 2 potassium ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Amine and polyamine biosynthesis; betaine biosynthesis via choline pathway; betaine from betaine aldehyde: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Dimer of dimers.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 7">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.8" evidence="4"/>
    <dbReference type="EMBL" id="PUGF01000017">
        <property type="protein sequence ID" value="PRC91992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91992">
        <property type="protein sequence ID" value="PRC91992"/>
        <property type="gene ID" value="S2091_3334"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00529">
        <property type="reaction ID" value="UER00386"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008802">
        <property type="term" value="F:betaine-aldehyde dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019285">
        <property type="term" value="P:glycine betaine biosynthetic process from choline"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00804">
        <property type="entry name" value="BADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011264">
        <property type="entry name" value="BADH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01804">
        <property type="entry name" value="BADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
        <property type="entry name" value="ALDEHYDE_DEHYDR_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 4" id="KW-0520">NAD</keyword>
    <keyword evidence="4" id="KW-0521">NADP</keyword>
    <keyword evidence="3 4" id="KW-0558">Oxidation</keyword>
    <keyword evidence="1 4 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-0630">Potassium</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldedh" evidence="8">
        <location>
            <begin position="26"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="4">
        <location>
            <position position="170"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="260"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="260"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="294"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4">
        <location>
            <position position="294"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="4">
        <location>
            <position position="472"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="35"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="101"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="158"/>
            <end position="160"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="184"/>
            <end position="187"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="238"/>
            <end position="241"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="254"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="262"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="4">
        <location>
            <position position="294"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="395"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="465"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="468"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="site" description="Seems to be a necessary countercharge to the potassium cations" evidence="4">
        <location>
            <position position="256"/>
        </location>
    </feature>
    <feature type="modified residue" description="Cysteine sulfenic acid (-SOH)" evidence="4">
        <location>
            <position position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC91992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="498" mass="53423" checksum="77CEAE7B1F742FD3" modified="2018-07-18" version="1">MSNANLNAFSNAGVQQLYIAGRRVDATSGKTFKVINPANGAVLAEVQRASKADVDAAVASAQAGQRIWAAMTAMQRSRILRNAVAILRARNDELAELETLNTGKALSETRAVDIVTGADVLEYYAGLVPAIEGQQIPLRDTSFVYTRREPLGVVAGIGAWNYPIQIALWKSAPALAAGNAMLFKPSEVTPLTTLKLAEIYTEAGLPDGVFNVLTGGGREVGTWLTEHPSIEKISFTGGTSTGKQVMASASSSTLKEVTMELGGKSPLIVFPDANLDRAADVAMMANFYSSGQVCTNGTRVFVHNSMKAAFEQKIVDRVRRIRVGDPLDLQTNFGPLVSFSHMDSVLKYIEIGKAEGARLLAGGGRVTTGSLAQGAYVEPTVFTDCTDNMTIVREEIFGPVMAILGFDDEDEVIRRANDTEYGLAAGVMTENLSRAHRVIHRLEAGICWINTWGESPAEMPVGGYKQSGVGRENGLMTLAQYTRVKSVQVELGAYTSVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWC0</accession>
    <name>A0A2S9GWC0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_3352</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the MIP/aquaporin (TC 1.A.8) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000017">
        <property type="protein sequence ID" value="PRC92010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92010">
        <property type="protein sequence ID" value="PRC92010"/>
        <property type="gene ID" value="S2091_3352"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015267">
        <property type="term" value="F:channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1080.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023271">
        <property type="entry name" value="Aquaporin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000425">
        <property type="entry name" value="MIP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00230">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00783">
        <property type="entry name" value="MINTRINSICP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81338">
        <property type="entry name" value="SSF81338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="34"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="85"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="123"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="154"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="195"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC92010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="238" mass="24683" checksum="F1A0285A47481E19" modified="2018-07-18" version="1">MNLTRRLVAEGLGTALLLAVVVGSGIMAERLSGANVAVALLANALATGAGLVALILMFGPISGAHFNPVVTLSEAWQKNIPMTEVAPYIAIQIIGAFAGVAAADGMFNLPLLFASEHIRTGPAQWWSEFVATFGLIAVIIGCSRSRPGVTPFAVAAYITAAYWFTSSTSFANPAVTLARAATNTFAGIRPSDTPGFILAQLLGAFAATLLFGWIYSTTPKNSTNGGTITSSDLTKKQC</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWQ3</accession>
    <name>A0A2S9GWQ3_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Zinc metalloprotease</fullName>
            <ecNumber evidence="9">3.4.24.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">S2091_3069</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the peptidase M50B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="9"/>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92153">
        <property type="protein sequence ID" value="PRC92153"/>
        <property type="gene ID" value="S2091_3069"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041489">
        <property type="entry name" value="PDZ_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004387">
        <property type="entry name" value="Pept_M50_Zn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008915">
        <property type="entry name" value="Peptidase_M50"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42837">
        <property type="entry name" value="PTHR42837"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17820">
        <property type="entry name" value="PDZ_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02163">
        <property type="entry name" value="Peptidase_M50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="SSF50156"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00054">
        <property type="entry name" value="TIGR00054"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 11" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="11" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6 9" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="101"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="375"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="426"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="domain" description="PDZ" evidence="10">
        <location>
            <begin position="194"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU362031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC92153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="449" mass="49331" checksum="2DB6DB99C5100389" modified="2018-07-18" version="1">MSFIHTALAFLFALCTLIVFHELGHYWVARLCNVKVLRFSLGMGKVLFSRRFGPDQTEWVISALPLGGYVKMLDSREQELGEIAPADLAREFTRQSVWKRIAIVAAGPLANFILAIFLFSILYMVGMPEPIAKLRHPAPSTQAYQAGIRGDELVTAVNSKPIQFWSELRWELLQQAVDKQAATLTLVSDGSTRQVTLSLDGLSPQDLETDFLSALGLSLALSKAQLGQVVPDGPAMRAGLQKDDIVTEIDGKVIFDSLDLIETVRASPNKLLQLKVSRSGAILEFTATPEAVTVNGQLIGKLNVEVRSTPEVLDHQESLFAAIQKASQRTWSTSVLTLKMIGKMVLGEVSLKNITGPLTIADYAGQTAKIGWISYVNFLAFISISLGVMNLLPIPVLDGGHLLYYSLEVLTGRPVSTRFWEMAQRAGLAILMILMFVAFFNDIVRLLPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWS8</accession>
    <name>A0A2S9GWS8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glutathione S-transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3090</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92174">
        <property type="protein sequence ID" value="PRC92174"/>
        <property type="gene ID" value="S2091_3090"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02798">
        <property type="entry name" value="GST_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="SSF47616"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GST N-terminal" evidence="1">
        <location>
            <begin position="12"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="2">
        <location>
            <begin position="94"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="221" mass="24529" checksum="E2FE26B3E5800684" modified="2018-07-18" version="1">MTLPMIPTITAFERSPDGGKGLARDMRVRWALEEVGQPYEVRLVSFTEMKASAHRTLHPFVQIPTYEEGDLALFESGAIVFHIAERNAGLLPDDANARARAITWMFAALNTMEPPIIDLGIARLMEGDKPWFEQRLPVVEDRIRIRLGELSVRLGDADWLDGAFSAGDLLMVSVLLRLSRSGILDEYPNLSAYVARGKARPAYQRAFDAQLAVFTGKPSSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWW3</accession>
    <name>A0A2S9GWW3_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">Malonyl CoA-acyl carrier protein transacylase</fullName>
            <ecNumber evidence="2 5">2.3.1.39</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_3129</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>holo-[ACP] + malonyl-CoA = CoA + malonyl-[ACP]</text>
            <dbReference type="Rhea" id="RHEA:41792"/>
            <dbReference type="Rhea" id="RHEA-COMP:9623"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57384"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78449"/>
            <dbReference type="EC" id="2.3.1.39"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the fabD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.39" evidence="2 5"/>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92213">
        <property type="protein sequence ID" value="PRC92213"/>
        <property type="gene ID" value="S2091_3129"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004314">
        <property type="term" value="F:[acyl-carrier-protein] S-malonyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014043">
        <property type="entry name" value="Acyl_transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024925">
        <property type="entry name" value="Malonyl_CoA-ACP_transAc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004410">
        <property type="entry name" value="Malonyl_CoA-ACP_transAc_FabD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016036">
        <property type="entry name" value="Malonyl_transacylase_ACP-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00698">
        <property type="entry name" value="Acyl_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000446">
        <property type="entry name" value="Mct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00827">
        <property type="entry name" value="PKS_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="SSF52151"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55048">
        <property type="entry name" value="SSF55048"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00128">
        <property type="entry name" value="fabD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PKS_AT" evidence="7">
        <location>
            <begin position="7"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="91"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR000446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000446-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC92213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="310" mass="33027" checksum="551096EFBBE3EAAD" modified="2018-07-18" version="1">MNKFAFVFPGQGSQAIGMLNGFADHPIVKQTVAEAADVLNFDLAKLIAEGPKEELDLTVNTQPVMLTAAVACYRAWLEAGGAKPAFVAGHSLGEYSALVAAGVLAFKDAVPLVRFRAQAMQEAVPFGVGGMAAILGLSDEDVRLVCLESAQGEIVEPVNFNAPAQVVIAGHKAAVERACEAAKARGAKRALVLAVSAPFHSSLLKPASDRLREYLQQVPFAEPQIQLINNVDVTILRDAADIKDALVRQAANPVRWVETIQKMAEQEITHIVECGPGKVLTGLVKRINSDLVGEALFDDASLNKILTLSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GX00</accession>
    <name>A0A2S9GX00_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Phosfate/sulfate permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_3163</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92247">
        <property type="protein sequence ID" value="PRC92247"/>
        <property type="gene ID" value="S2091_3163"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005315">
        <property type="term" value="F:inorganic phosphate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006817">
        <property type="term" value="P:phosphate ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001204">
        <property type="entry name" value="Phos_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11101">
        <property type="entry name" value="PTHR11101"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01384">
        <property type="entry name" value="PHO4"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="49"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="84"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="111"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="139"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="222"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="256"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="310"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC92247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="336" mass="35731" checksum="434CE27F6C9A8D00" modified="2018-07-18" version="1">MHTLQLSIYVLVLLVGIALIFDFMNGFHDAANAIATVVSTGVLKPQTAVAMAAFFNVVAFFVFPTHVASMIGKGMIDPTVIDQYVIFGALIGAVSWNFLTWYFGIPSSSSHALIGGLVGAAVAKGGVVTLVAKGLWMTVLFIVLSPLLGFIFGSLMMLLVSWLFVRSTPKKVDKWFRRLQLGSAAMYSLGHGGNDAQKTMGIIWMLLIATGYSQSTDLNPPVWVAMSCYAAIGFGTLFGGWRIVKTMGQKITKLKPVGGFCAETGGAITLFMATALGVPVSTTHTITGAIVGVGAAHRISAVRWGVAGNIVWAWIFTIPASAFVAAVAWWVGKLFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GX54</accession>
    <name>A0A2S9GX54_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2947</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92288">
        <property type="protein sequence ID" value="PRC92288"/>
        <property type="gene ID" value="S2091_2947"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="84" mass="9536" checksum="52926A368142E40F" modified="2018-07-18" version="1">MRMTDTTSAALTFVIPRNWRLFLVVFLVKMWRLKACPHLIVPPGRTRKRFLAELLVFIFGITLLSVKDSSNFNVIVGGSELATL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GX60</accession>
    <name>A0A2S9GX60_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2966</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92307">
        <property type="protein sequence ID" value="PRC92307"/>
        <property type="gene ID" value="S2091_2966"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="83" mass="9297" checksum="CE59D491EB2326FD" modified="2018-07-18" version="1">MVVVSMGSEDVAFIFEENSSDFQQIAVQGQVTYRINDFKKIASLLNFLINPIHSFGHHVAYICPLRFELGSDNIKSNSCLAMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GX65</accession>
    <name>A0A2S9GX65_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2915</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92256">
        <property type="protein sequence ID" value="PRC92256"/>
        <property type="gene ID" value="S2091_2915"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="119" mass="12973" checksum="FDFA4AF4DB18A02B" modified="2018-07-18" version="1">MNKDLSIDEFDALEQISRLSKNVKPTACVNRNAKRLCGIKLASYRKDGQLELTEQGNAALFAKQCIDGLRAVQSNPQAQLSADVAAFLGKKSYISSSPEGTQISQRGLECLADIDAQRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GX75</accession>
    <name>A0A2S9GX75_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Putative metalloendopeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">S2091_2983</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92324">
        <property type="protein sequence ID" value="PRC92324"/>
        <property type="gene ID" value="S2091_2983"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08662">
        <property type="entry name" value="M13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1380.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000718">
        <property type="entry name" value="Peptidase_M13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018497">
        <property type="entry name" value="Peptidase_M13_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042089">
        <property type="entry name" value="Peptidase_M13_dom_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008753">
        <property type="entry name" value="Peptidase_M13_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11733">
        <property type="entry name" value="PTHR11733"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01431">
        <property type="entry name" value="Peptidase_M13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05649">
        <property type="entry name" value="Peptidase_M13_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00786">
        <property type="entry name" value="NEPRILYSIN"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51885">
        <property type="entry name" value="NEPRILYSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015542929" evidence="8">
        <location>
            <begin position="26"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M13_N" evidence="10">
        <location>
            <begin position="46"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M13" evidence="9">
        <location>
            <begin position="477"/>
            <end position="669"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF05649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC92324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="682" mass="75698" checksum="258DA03695779E5F" modified="2018-07-18" version="1">MFKKTPLQIGFAAALLCFAAPSFSAASGFVNGLVIEPQTMDRSADPCTDFFEFSNGQWLKDNPIPEDRSRYSAYDEVTERNLSALKKIAENAAKNPDKATPAQRIVGAYFHSGMDEAGIEAAGAKPLAEGLAQIAAIQTRTQLMDAIAQQHQIGAAPLFNFYIDQDAKNTLRYIPQLAQGGLGLPDRDYYLKSDAKTLEIRSKYSAHLEKMFSLLGDTPEVAKHNAAIVLSMETRLARASMSKIELRDPQASYHLMTLAGLAKIDHGTDWTNYFNQIGLKAPGEINVAQPKFFAEAGHMLKNVKIADWQTYLRWNLVNASANDLSTAFVNANFDFYGRTLAGTKELQPRWKRVLTNIDKNVGDALGELYVAQFFSPAAKAGVLEMVNNIKVAMHESIDNLAWMSATTKLQAIKKLDAINVKIGYPDKWRDYSALVIDADSYANDNMRANQFEFKRMIAKLGKPIDRNEWGMTAPTVNAYYNPTMNEIVFPAGILQPPLYHLDADLASNYGNTGATIGHEMTHAFDDEGRQFNADGNLKSWWTKQDEKNFIQRASAIEKQFDEFNPIDNLHINGKLTAGENIADLGGMKIALQALRTALKGKPQVELIDGLTPEQRYFVANAQSFRGLTRPEQLRLQLATDPHAPEYARVLGPIANMPEFTAAFNCPADKSPLRPSNKLVNIW</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXB2</accession>
    <name>A0A2S9GXB2_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Heme chaperone HemW</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_3012</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92353">
        <property type="protein sequence ID" value="PRC92353"/>
        <property type="gene ID" value="S2091_3012"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004109">
        <property type="term" value="F:coproporphyrinogen oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006779">
        <property type="term" value="P:porphyrin-containing compound biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034505">
        <property type="entry name" value="Coproporphyrinogen-III_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010723">
        <property type="entry name" value="HemN_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004559">
        <property type="entry name" value="HemW-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13932">
        <property type="entry name" value="PTHR13932"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06969">
        <property type="entry name" value="HemN_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00562">
        <property type="entry name" value="HemN-like__clustered_with_heat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00539">
        <property type="entry name" value="hemN_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="2" id="KW-0143">Chaperone</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2" id="KW-0349">Heme</keyword>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="3">
        <location>
            <begin position="38"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU364116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC92353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="417" mass="46893" checksum="4F3D252DD101178A" modified="2018-07-18" version="1">MIIPIKPVSGLPSTKKNTPAELNANVAQKFMQPGSLSLAALPPLALYIHIPWCVKKCPYCDFNSHEAKNGFPEDEYLSALRLDLERALPAIWGRKIYTIFIGGGTPSLLSAAGLDRLLSDVRTLLPLDGAVEITMEANPGTFEAEKFRSYRASGVNRLSIGIQSFNSQHLQALGRIHDGDEARRAIEIAQTHFDNFNLDLMYALPKQTLSEARLDVQTAIASGAPHLSLYHLTLEPNTLFAKYPPALPDDDASAEMQDEITEIMTAAEYQHYEVSAYAKEKHQARHNLNYWQFGDYLGIGAGAHSKLSFPHRVVREMRYKNPKAYMQAVSEGREIQESNEITRDDMAFEFMLNTLRLTDGFPVNLFAERTGLSLTTIEHSLHNAEKKGLIYRDHQQIRATELGMRFLNDLQQMFLKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXD0</accession>
    <name>A0A2S9GXD0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3036</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92377">
        <property type="protein sequence ID" value="PRC92377"/>
        <property type="gene ID" value="S2091_3036"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032874">
        <property type="entry name" value="DDE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13610">
        <property type="entry name" value="DDE_Tnp_IS240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_Tnp_IS240" evidence="1">
        <location>
            <begin position="75"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="237" mass="28372" checksum="2E1D3F2F82E31D9E" modified="2018-07-18" version="1">MNSTKPLYFRRRFPSEIISHCVWLYFRFSLSYRDIEEMMAKRGVIVSYETIRDWSHKFGGIYAKRLRARSTRPNDHWHLDEVYLSINGKAHYLWHAVDQDGEILDILVQPRRNKYAAKKFFRKLLKKLHYIPRVIITDKLRSYAAAKAEIMPEVKHVQDKGANIRAENSHQPTRERERRMRGFKSARHAQRFLASYSVIGSFFCPGRHVLAAKNYREIMRQRFIQWNEIVSFGFTFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXD6</accession>
    <name>A0A2S9GXD6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2760</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92385">
        <property type="protein sequence ID" value="PRC92385"/>
        <property type="gene ID" value="S2091_2760"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="117" mass="13193" checksum="11731DDBBBE7C855" modified="2018-07-18" version="1">MSSKLLIYIGENEKFDVARTTEVISSIVGTSDAKLENFIGAIFECNYTFQDRTTIVRISEELKTVTVEGLGVESLNFALEFQRMMSCALHAIDMEYSFDVDLRNFQSIEDLMSAIDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXD9</accession>
    <name>A0A2S9GXD9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3038</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92379">
        <property type="protein sequence ID" value="PRC92379"/>
        <property type="gene ID" value="S2091_3038"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="117" mass="13367" checksum="32D5C5D9AA19F90C" modified="2018-07-18" version="1">MKGCEMKLNWTWFMSVDFRGDWIMTKGWAHLQIDVNKISGFMFFDEKYNEADIYARFSGYFDDDNFAVVTVSSAQEGTPEFEVSGPIFSFKNENILASSFILTDGTTVLGFTNHAEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXK5</accession>
    <name>A0A2S9GXK5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Rhodanese-related sulfurtransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2815</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92440">
        <property type="protein sequence ID" value="PRC92440"/>
        <property type="gene ID" value="S2091_2815"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="SSF52821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Rhodanese" evidence="1">
        <location>
            <begin position="19"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="109" mass="12157" checksum="205A0AB73BEB3B48" modified="2018-07-18" version="1">MDVISISAPELANWLADANRQPPVLLDVRELSELQHCQIPASLHIPMHSVPPRMNELDSAAAIVCICHHGARSMQVARFLKQHDFEHVINLTGGIHAWAVQVDTTMETY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GY87</accession>
    <name>A0A2S9GY87_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative chitinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2742</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92687">
        <property type="protein sequence ID" value="PRC92687"/>
        <property type="gene ID" value="S2091_2742"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004568">
        <property type="term" value="F:chitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016998">
        <property type="term" value="P:cell wall macromolecule catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006032">
        <property type="term" value="P:chitin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000726">
        <property type="entry name" value="Glyco_hydro_19_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023346">
        <property type="entry name" value="Lysozyme-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00182">
        <property type="entry name" value="Glyco_hydro_19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53955">
        <property type="entry name" value="SSF53955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyco_hydro_19_cat" evidence="1">
        <location>
            <begin position="74"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="171" mass="18819" checksum="A71C50AD9A56B60F" modified="2018-07-18" version="1">MDISQLQKIMPLARQRANTFLDPLIAAMSEFEINTPMRQAAFLAQVAHESGQLLYVLELASGEAYEGRKDLGNTQSGDGPRFKGRGLIQITGRTNYAAMSEALKLDCVNHPELLELPTNACRSAGWFWKNHGLNVLADSQSFITITRRINGGTNGLADRQALYAIAKKVLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GY97</accession>
    <name>A0A2S9GY97_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2733</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92678">
        <property type="protein sequence ID" value="PRC92678"/>
        <property type="gene ID" value="S2091_2733"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015716895" evidence="1">
        <location>
            <begin position="20"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="115" mass="13078" checksum="9EF7EB11191634DE" modified="2018-07-18" version="1">MKKIIVAIGLLLAATYALADCPALEYQEMKDMNTPDLTGEYCKTTANQDRYLKSSKSNSELLVLSEGKERNDYFELFKKDKESAEQCQSQSERIKRVLIAKNTSEEDLKTACQKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYD0</accession>
    <name>A0A2S9GYD0_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6438 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2462</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92732">
        <property type="protein sequence ID" value="PRC92732"/>
        <property type="gene ID" value="S2091_2462"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045497">
        <property type="entry name" value="DUF6438"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20033">
        <property type="entry name" value="DUF6438"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015665080" description="DUF6438 domain-containing protein" evidence="1">
        <location>
            <begin position="34"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6438" evidence="2">
        <location>
            <begin position="340"/>
            <end position="415"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="460" mass="51524" checksum="E8B54BA68C3FAAE0" modified="2018-07-18" version="1">MPEFKKTLTAKWLKLSKITAMLVIMLLPFSAHADSPTITSIKSFGESTRIIDGTARDNLIDWGDTQLKSSSEIQIKSIGFSVYPHFNFVGGTLRWQLAGTFRPDTKISKVSIDLVSADQMVYHLVADISPEVNPTGWFLSTPDSLIGPKSLPWLFKTGAAKLHFVFTFKVAGKSDLKFDEPAILPNRTRLWILEQGDIEFSSAQKTDSAKPFSVPACDGKKLAAYRPSDEEVALHRNGMAPFSEYTFDTRPPGSWNFHLATMVDEKGNVVCYVSTIAAGEDTVLDDNRKQLITSIARNGYKPFLMGGKPVPAMVAEQVLEQERPERHIPLPDVPLNRIQITLDRAGCMNSCPSYRVEIFGTGLVIFRNRAGSNASKIHRYHIPLSEVKKLVSEMKATEIWSLRSKFRDQSFDGPTYRLKIDFGGEIHTIESYEGERDGMPGYVTDFENMIDRIGLSFKRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYH2</accession>
    <name>A0A2S9GYH2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycine zipper 2TM domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2491</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92761">
        <property type="protein sequence ID" value="PRC92761"/>
        <property type="gene ID" value="S2091_2491"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019867">
        <property type="term" value="C:outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008816">
        <property type="entry name" value="Gly_zipper_2TM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05433">
        <property type="entry name" value="Rick_17kDa_Anti"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rick_17kDa_Anti" evidence="2">
        <location>
            <begin position="144"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="50"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="233" mass="23309" checksum="21D4C6860A284FD6" modified="2018-07-18" version="1">MDVDNKASKLHPLAIAAAAAVILVSLTGVAAMTGVLPNFSKSATPEATTTAAAETATSAPVTDSASASTAAETPASTTKTAAKKPTAKPTYTSGSNAPIYADNQVSQANANPEPIAPPAPPPCPNCGVVETTRTIQQQAPASGIGAGVGALLGGVLGHQVGGGNGRTLATVAGAIGGGLAGNAVEKNTHTTTTYEVIVRMEDGTKQRFILSTQRWRSGDLVRVDNGNLSSRDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYY0</accession>
    <name>A0A2S9GYY0_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DNA topoisomerase 4 subunit A</fullName>
            <ecNumber evidence="5">5.6.2.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Topoisomerase IV subunit A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">parC</name>
        <name evidence="8" type="ORF">S2091_2320</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>ATP-dependent breakage, passage and rejoining of double-stranded DNA.</text>
            <dbReference type="EC" id="5.6.2.2"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="5">Heterotetramer composed of ParC and ParE.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.2" evidence="5"/>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92903">
        <property type="protein sequence ID" value="PRC92903"/>
        <property type="gene ID" value="S2091_2320"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019897">
        <property type="term" value="C:extrinsic component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003918">
        <property type="term" value="F:DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006265">
        <property type="term" value="P:DNA topological change"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00187">
        <property type="entry name" value="TOP4c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.268.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.199.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00936">
        <property type="entry name" value="ParC_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006691">
        <property type="entry name" value="GyrA/parC_rep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035516">
        <property type="entry name" value="Gyrase/topoIV_suA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013760">
        <property type="entry name" value="Topo_IIA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013758">
        <property type="entry name" value="Topo_IIA_A/C_ab"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013757">
        <property type="entry name" value="Topo_IIA_A_a_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002205">
        <property type="entry name" value="Topo_IIA_dom_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005742">
        <property type="entry name" value="TopoIV_A_Gneg"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03989">
        <property type="entry name" value="DNA_gyraseA_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00521">
        <property type="entry name" value="DNA_topoisoIV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00434">
        <property type="entry name" value="TOP4c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101904">
        <property type="entry name" value="SSF101904"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56719">
        <property type="entry name" value="SSF56719"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3 5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4 5 8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0799">Topoisomerase</keyword>
    <feature type="domain" description="TOP4c" evidence="7">
        <location>
            <begin position="33"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="active site" description="O-(5'-phospho-DNA)-tyrosine intermediate" evidence="5">
        <location>
            <position position="144"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="5">
        <location>
            <position position="64"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="5">
        <location>
            <position position="100"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="5">
        <location>
            <position position="102"/>
        </location>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="5">
        <location>
            <position position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC92903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="783" mass="84689" checksum="47B20A709822955C" modified="2018-07-18" version="1">MPVQTDLFSDDSSKNVPPTPPVPPSPPSDDESITLANFAERAYLDYAISVVKGRALPDVCDGQKPVQRRILYAMNELGLSATAKPRKSALVVGEVLGKLHPHGDQSVYDALVRMTQDFSLRYPLIDGQGNFGSRDGDGAAAMRYTEARLTPIAGLLMDEIDSGTVDFQPNYDGSSNEPRLLPARLPMVLLNGASGIAVGLATEIPSHNLTEIAQAAIALIKNPALTHSELMEIVPGPDFPGGGQIISPTAAISDIYLGGRGSLKVRACWKIEELARGQWQVVINELPPGTSSQKILEEIEECTNPKIKLGKKTLTPEQQNLKQLMLGVLDTIRDESGRDAPVRLVFEPKSKNQSSAELMQILLAHTSLETNSSMNLVMIGGDGRPRQKGLLEIISEWVAFRFVTVTRRSEFKLKKVEDRIHILEGRIAVLLNIDAVIRIIRESDLPKPALIEAFNLSDRQAEDILEIRLRQLARLEAIKIEQELAALRTEQAGLQDLLENPASMKRKIIKEIEVDQKQFGDARRTLIEVAQKAVIEQKVIDEPVTVVISQKGWLRARTGHGHDAAQFTFKAGDTLQSTFECRSVENLLAFDSNGRVYSVAVSALPGARGDGVPITSLIDLASGARILHYFAGDAATILLLAGTGGMGFTASVADMTGRMKAGKAFINFDAGDELLTPSVVKPDSSAIACLSEKGRLLVFGLTECKHLASGGKGVILMDLEAGEKLLAVQTISQKGVTVSGIGRAAKPQEVSLSATNLAPHINKRARKGRVLESKLKPVSLKAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZ28</accession>
    <name>A0A2S9GZ28_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Bacterial extracellular solute-binding protein, family 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2406</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92989">
        <property type="protein sequence ID" value="PRC92989"/>
        <property type="gene ID" value="S2091_2406"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001638">
        <property type="entry name" value="Solute-binding_3/MltF_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00497">
        <property type="entry name" value="SBP_bac_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00062">
        <property type="entry name" value="PBPb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="PBPb" evidence="2">
        <location>
            <begin position="29"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="252" mass="28778" checksum="7F041FE3F44382A5" modified="2018-07-18" version="1">MNRSVFLSRYCIVGWLMVLLYSFPLKATELQVVTDDMPPLNYVEQGVVTGFATEVLQATLHAAGLQASFTVFPWARAYQTALTQPNTLIFPTTRTPERESLFAWVGPIIPREIFVYKLRERNDIRMDKLSDAANYHVGLIRAYASSKDFLSASGVAENKIDYAPTEESNMKKLFLKRIDLIISDELSAAFWAKSLNRKNEELEQVLLFDSRYSYYFALNKQSDPKMLAKLRAALAEVQSSGQVKKLRDKYLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZ99</accession>
    <name>A0A2S9GZ99_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Phosphate regulon sensor protein PhoR</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_2116</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Member of the two-component regulatory system PhoR/PhoB involved in the phosphate regulon genes expression. PhoR may function as a membrane-associated protein kinase that phosphorylates PhoB in response to environmental signals.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93030">
        <property type="protein sequence ID" value="PRC93030"/>
        <property type="gene ID" value="S2091_2116"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004721">
        <property type="term" value="F:phosphoprotein phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006817">
        <property type="term" value="P:phosphate ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021766">
        <property type="entry name" value="PhoR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014310">
        <property type="entry name" value="Sig_transdc_His_kinase_PhoR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13188">
        <property type="entry name" value="PAS_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11808">
        <property type="entry name" value="PhoR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02966">
        <property type="entry name" value="phoR_proteo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0592">Phosphate transport</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="7"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="8">
        <location>
            <begin position="212"/>
            <end position="427"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00025207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC93030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="430" mass="48674" checksum="8503E7CD5789AE88" modified="2018-07-18" version="1">MNPLIVFWVPAILRTLIVVCGALVVGYFWGILWCAIAVGSGLAVLIGLQLHYLYRLSIWLDKPDSSKLPDGWGAWTEIFSRLYRMRREDEKNQAELSEWLARFRQAMTLLPDGVVIMDDVLFLEWCNPVAEQHLGLSLSKDKNMRVTNLIRSPEFMDYVILGRFDKPLTVTHRDRKLILHIIKFENRRQILVTHDITESERIDMMRRDFIANASHELRTPLTVINGFLEINAMQPDLDSKIRAGHIKLMTEQGQRMQGLVEDMLTLTRLESVDFPVRPERVNMTQLLESVVSEMHGLSVGKHELIFINEGPDVMGSFDELRSAFGNLVSNAVRYTPVGGTITISWTNSDAGPKFMVKDSGIGISSEHISRLTERFYRVDKSRSRETQGTGLGLAIVKHVALRHKAQLTIESTSGVGSAFSIQFPMPVSIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZB1</accession>
    <name>A0A2S9GZB1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Bacteriophage CII protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2158</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93072">
        <property type="protein sequence ID" value="PRC93072"/>
        <property type="gene ID" value="S2091_2158"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007933">
        <property type="entry name" value="Transcrpt_activ_CII"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05269">
        <property type="entry name" value="Phage_CII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="100" mass="10884" checksum="1EDDBEACD6304FA3" modified="2018-07-18" version="1">MNPLSAEDVERSRKNHAIILSRLASVGQSTVANGIGVHESTISKMKDGDLERFAKIAAVLGLKVVPVEMKCYPADKMDAILILARSNLNEISCVEQLSFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZK0</accession>
    <name>A0A2S9GZK0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PepSY-associated TM helix</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2219</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93133">
        <property type="protein sequence ID" value="PRC93133"/>
        <property type="gene ID" value="S2091_2219"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005625">
        <property type="entry name" value="PepSY-ass_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34219">
        <property type="entry name" value="PTHR34219"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03929">
        <property type="entry name" value="PepSY_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="161"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="216"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="368"/>
            <end position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="404" mass="45033" checksum="40D4FDA9B9ACEE4B" modified="2018-07-18" version="1">MSIRPLFVILHRWFGLAAALFLFIAGATGAFISWDHELDAWLNPQLFKAHSAKQLPGMEALPGLALANQVEAQDKRLRVTYVLTESDAAHTSMMMVEGRTDPATKRPFALGFNQIAVDPVTAEIQGKRMWGALSLDRENLLPFLYKLHYTMFLPDVGGIELGIWLMGIIGVIWAFDCFIALWLSFPNWRSWRKSFVFRWQQGGHKLNFDVHRSGGVWLWILLLILAVTSVSMNLERPLIRPIIQFFSPLTPDIFDSRKPLAPEHTVEASFSREQVVELAADEGRRRGWSLPVGGIFYSSEFGVYGVGFFNAGNDHGDIGLGNTWLYFDADNGQLAGSKIPGTGSAGDLFLQAQFPLHSGRILGLTGRILISIMGIAVALLSATGVIIWARKRRARLLSARQRVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZW6</accession>
    <name>A0A2S9GZW6_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C</fullName>
            <shortName evidence="1">Asp/Glu-ADT subunit C</shortName>
            <ecNumber evidence="1">6.3.5.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">gatC</name>
        <name evidence="2" type="ORF">S2091_2009</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O + L-aspartyl-tRNA(Asn) + L-glutamine = ADP + 2 H(+) + L-asparaginyl-tRNA(Asn) + L-glutamate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:14513"/>
            <dbReference type="Rhea" id="RHEA-COMP:9674"/>
            <dbReference type="Rhea" id="RHEA-COMP:9677"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:78515"/>
            <dbReference type="ChEBI" id="CHEBI:78516"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O + L-glutamine + L-glutamyl-tRNA(Gln) = ADP + H(+) + L-glutamate + L-glutaminyl-tRNA(Gln) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:17521"/>
            <dbReference type="Rhea" id="RHEA-COMP:9681"/>
            <dbReference type="Rhea" id="RHEA-COMP:9684"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:78520"/>
            <dbReference type="ChEBI" id="CHEBI:78521"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Heterotrimer of A, B and C subunits.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the GatC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.-" evidence="1"/>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93271">
        <property type="protein sequence ID" value="PRC93271"/>
        <property type="gene ID" value="S2091_2009"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050566">
        <property type="term" value="F:asparaginyl-tRNA synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050567">
        <property type="term" value="F:glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006450">
        <property type="term" value="P:regulation of translational fidelity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00122">
        <property type="entry name" value="GatC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003837">
        <property type="entry name" value="Asp/Glu-ADT_csu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036113">
        <property type="entry name" value="Asp/Glu-ADT_sf_sub_c"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15004">
        <property type="entry name" value="PTHR15004"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02686">
        <property type="entry name" value="Glu-tRNAGln"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141000">
        <property type="entry name" value="SSF141000"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00135">
        <property type="entry name" value="gatC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0436">Ligase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="100" mass="11188" checksum="01D079398D43E497" modified="2018-07-18" version="1">MSLKETDVTRIAHLAHLELNAEQTSKTLEQLNGIFALVEKMQTIDTAGIEPLSHPFALVVDHLALRLREDLVTETNHREAYQQSAPATQDGLYLVPKVIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZW9</accession>
    <name>A0A2S9GZW9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2023</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93285">
        <property type="protein sequence ID" value="PRC93285"/>
        <property type="gene ID" value="S2091_2023"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="182" mass="20225" checksum="D2573A517CD70137" modified="2018-07-18" version="1">MNADLKNFREWYVYTLNGMYPRRESGIAVFILSLPLLERYLRQKNGLTPSDGLSDACMTDLYNLFGALANVQVARKFWNVYRNGFLHEATLSLKTSGGKDLPVGVLSHDIQDAITVEANGSFLVHPVLFSQCVIQVIEKNFAVFSGAGTSLPTVNRYKLIPEPPSGPHFYEGTSAAWVPKKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0E6</accession>
    <name>A0A2S9H0E6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_1807</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93420">
        <property type="protein sequence ID" value="PRC93420"/>
        <property type="gene ID" value="S2091_1807"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002372">
        <property type="entry name" value="PQQ_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_supfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13360">
        <property type="entry name" value="PQQ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="SSF50998"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="1" id="KW-0564">Palmitate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015450795" evidence="3">
        <location>
            <begin position="27"/>
            <end position="611"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC93420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="611" mass="65294" checksum="CC6D533B599C2209" modified="2018-07-18" version="1">MQFRTILKRGAVGAAFVLCGLATAQAQSNGDWPLYSHDYSNTNSNPDEVLISRQTAPKLQRAWSTFNDSQWRPTPPPTGFVLEGALGLKFPASVVGVIAPPLIRNGTIYYIDVLGTMFARDAKTGTITDPARHWTTTLVDPDYLLQAQPIGPEMYYAAPVISDGIIWIHSSLNGRIHAIRQIGGAELDFDPTTPGIQPLALVPDQQLASNLGEPVIVTVPSTTGARKLFVTEVNVILNDALIQGGQAGFVVAMDITDPAHPFEAWRTSTIDINPATGKRYGAGVSAGSGFAVDHKLHLIYGGTGQNTVTPYPGYPDATHAPAGYIDRSDSLYAIDYRTGKFVWVSQFHKGDVFDINNPVSAGPERTDGPRDADVLSPPVMFTARTADGQMHDLVGAGSKGGLYRVVDRATGATIWQKQISKPTGLGGIQAGSAYANGIIYVAGFEGIDDGFSDANFDTPTSKYKNAFFATFSPAFWADVEDVRDDRLAITGMQTKVYALDAGTGNPVWKVAGTGDYLLLKVGATMRHLSLANGLLYITTSSGQLFVVSTLDGSQLYTDQTQDLNALFNLGLGKPHHASMNGGTLISNGMVFVPYGAQNNPSGGMIAYRLGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0F8</accession>
    <name>A0A2S9H0F8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2084</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93346">
        <property type="protein sequence ID" value="PRC93346"/>
        <property type="gene ID" value="S2091_2084"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000551">
        <property type="entry name" value="MerR-type_HTH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13411">
        <property type="entry name" value="MerR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00422">
        <property type="entry name" value="HTH_MERR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50937">
        <property type="entry name" value="HTH_MERR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH merR-type" evidence="2">
        <location>
            <begin position="10"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="91"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="161" mass="18438" checksum="65C0DF340B90BFDF" modified="2018-07-18" version="1">MLPLTKPAITYTITELSREFDITPRAIRFYEDQGLLSPQREGPGGRNRVYTARERTHLKLTLRGKRLGLSLSDIKSLVDMYSSPKDTEPQLQRFIAVLAQHRAALEQQQEDIDVLLTEISAHEEECQRILKAELKTESKSETKLENKPEINIKPKAIVIRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0G0</accession>
    <name>A0A2S9H0G0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Poly(3-hydroxyalkanoate) synthetase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_1861</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93474">
        <property type="protein sequence ID" value="PRC93474"/>
        <property type="gene ID" value="S2091_1861"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042619">
        <property type="term" value="P:poly-hydroxybutyrate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010941">
        <property type="entry name" value="PhaC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022211">
        <property type="entry name" value="PHBC_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07167">
        <property type="entry name" value="PhaC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12551">
        <property type="entry name" value="PHBC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PHBC_N" evidence="4">
        <location>
            <begin position="36"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="domain" description="PhaC_N" evidence="3">
        <location>
            <begin position="118"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF12551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC93474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="602" mass="67601" checksum="B0FD1F96795630B0" modified="2018-07-18" version="1">MDELILEKSAPITFKSSPIRIPDVQHINTSEPVDSANQLDLITNAWIGRFTGNISPAALINAYNDWLTHLRLSPSKKAELTNKALKKFWRWTTYACDPAQMLPSFNNESQHCITPLPQDKRFIDKAWENWPFNVMTQGFLLNQQWWHNATTNVRGVSQHHEDVVTFTTRQILDMWAPSNFLLTNPVVLKQTMREGGANLLRGAQNAFADWQRSSGAGSDSTSAFKVGENLAVTPGKVIYRNRLIELIQYSPSTESVHAVPVLIVPAWIMKYYILDLSAQNSLVNYLVEQGHTVFMISWKNPDASDRDLSMDDYHNLGVMEAIDTVSRVTGAEQINSVGYCLGGTLLSIAAAAMARDGDTRLASITLFAAQVDFTEPGEMSLFIDESQISFLEAVMWEQGYLDSTQMAGAFQLLRSNDLIWSHRLNQYLLGMKETESDLMAWNADATRMPYRMHTEYLRHLFLHNDLAEGRYRVNSKVVNLTDIHVPIFAVGTTTDHVAPWHSVFKIQRLTEAELTFLLTSGGHNAGVVSPPGHPHRSYQVATRAQGDAVVDADTWQTTLPVHEGSWWPTWEAWLASRSGQSIKPPAINNPICDAPGVYIMQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0X6</accession>
    <name>A0A2S9H0X6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Hemin uptake protein hemP</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1619</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93618">
        <property type="protein sequence ID" value="PRC93618"/>
        <property type="gene ID" value="S2091_1619"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019600">
        <property type="entry name" value="Hemin_uptake_protein_HemP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10636">
        <property type="entry name" value="hemP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="64" mass="7526" checksum="CB8962A3E65DE8F4" modified="2018-07-18" version="1">MIPLKQPVPASQQETKDAKKTEKVETLRILSKDIMRNLRELEIDHEGRIYRLRITQLNKLILTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H149</accession>
    <name>A0A2S9H149_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ABC-type branched-chain amino acid transport systems periplasmic component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1715</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93714">
        <property type="protein sequence ID" value="PRC93714"/>
        <property type="gene ID" value="S2091_1715"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028081">
        <property type="entry name" value="Leu-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13458">
        <property type="entry name" value="Peripla_BP_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peripla_BP_6" evidence="1">
        <location>
            <begin position="57"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="425" mass="46341" checksum="C0910FB4AAEA6DD6" modified="2018-07-18" version="1">MKNHQLIFSLPIAVARPPFLTPSGVATMINRRDFLKFSALAAPGLLPASNIFAQTNTIRFGCPVPMSGPFAANGKFSEMGMKFAIQQAGKVIGKELSYTAIDTEGKPATAVRKVKDSIEKGTRFFIGGALSSESLAMGKEAARANSVFVTAAGADEITGNECNRATLRWSVPTFGAIEQTVRPLLDQFPNAKRWYTITPQYVFGDGLLATAKNIFKEKGIEHVGNSSHSLAEKEFSGYLTNAMAAKPDVLLLLNFGSQSSDMLRQAVSFGLKNKMKILMAWASGLEQFETLGANICEGVYFGVQYWHGVDAPFNKQFVSNVNNHLKIDPNYSFAAIYMGTKIVLDAITKANSTDPKAVIAAIEGMKYEGITGTEEIRASDHQVIKNYYLLKGKAKSAMRNKNDYVDIISFGKSFLPLDKTMCKMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H156</accession>
    <name>A0A2S9H156_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Penicillinase repressor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1597</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the BlaI transcriptional regulatory family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93596">
        <property type="protein sequence ID" value="PRC93596"/>
        <property type="gene ID" value="S2091_1597"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005650">
        <property type="entry name" value="BlaI_family"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34134">
        <property type="entry name" value="PTHR34134"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03965">
        <property type="entry name" value="Penicillinase_R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="124" mass="14310" checksum="EAF4E367EF983D6E" modified="2018-07-18" version="1">MSIPSITELSLLKALWKQQPLSAREIHESVVEELNWSFSSTRKTLERMLEKQMVSQQTLHGVLVYQPSLDKVNTLAAFAHDFGRRVMEMDAPLPVNMFTGSKLVDQRELAELEQLLRDWPTDQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H157</accession>
    <name>A0A2S9H157_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1699</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93698">
        <property type="protein sequence ID" value="PRC93698"/>
        <property type="gene ID" value="S2091_1699"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021344">
        <property type="entry name" value="DUF2970"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11174">
        <property type="entry name" value="DUF2970"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="72" mass="7848" checksum="DF7FE20275AABA2D" modified="2018-07-18" version="1">MSDLKDASQRKLSFFATIKAVCWSFVGLRKKSSYEQDAAKLNPIYVVIAGISVAAIFIATLILIVKSVVANQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H187</accession>
    <name>A0A2S9H187_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Flavoprotein, TIGR03862 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1729</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93728">
        <property type="protein sequence ID" value="PRC93728"/>
        <property type="gene ID" value="S2091_1729"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004792">
        <property type="entry name" value="BaiN-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022460">
        <property type="entry name" value="Flavoprotein_PP4765"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023166">
        <property type="entry name" value="HI0933-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42887">
        <property type="entry name" value="PTHR42887"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03862">
        <property type="entry name" value="flavo_PP4765"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00275">
        <property type="entry name" value="TIGR00275"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="413" mass="44771" checksum="D58B20A92EBAC781" modified="2018-07-18" version="1">MNLKNSVPNIVVIGGGPAGLMAAETLAQGGAQVDLFDAMPSVGRKFLLAGKGGLNLTHAEDLSDFMRRYGSRQVAINSWINEFNPQNLRQWAKNLGVETFVGTSGRVFPADMKAAPLLRSWLHRMRTKGVRFHMRHRWTGWKDNALSFSTPDGEVLHKADAIVLALGGASWPQLGSNGAWLPLLAEKGVDIAPLEPSNCGFEVTWSEHFKTNFAGEPLSPIAITHTNATGTSSRRLGQFVVTEHGVEGSLIYALSGLFREQIKAQGSAQIYLDLLPDLPLHRAVQHCEHPRGSRSVAGHLQSRLNLRGVKTALLREFCTPETLQDPVLLANAIKALPITLLAPRPIAEVISTAGGVKLEAMNRNLMLNEMPGVFCAGEMLDWEAPTGGYLLTACFASGKVAGKAALDWYAKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1E7</accession>
    <name>A0A2S9H1E7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative toxin-antitoxin system antitoxin component, TIGR02293 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1397</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93788">
        <property type="protein sequence ID" value="PRC93788"/>
        <property type="gene ID" value="S2091_1397"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011979">
        <property type="entry name" value="Antitox_Xre"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024467">
        <property type="entry name" value="Xre/MbcA/ParS-like_toxin-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09722">
        <property type="entry name" value="DUF2384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02293">
        <property type="entry name" value="TAS_TIGR02293"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF2384" evidence="2">
        <location>
            <begin position="113"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="163" mass="17907" checksum="9BB1AD28AFF36B8B" modified="2018-07-18" version="1">MQNKLTHKSATHAATKAISPRARSPEIKQPATIYAVPTLRASAEQIARTRLGIPASDIIEVAKMIGMPRDKFYACVGLPKSTIEKNISQQSPLSTAHGDRLYRVNRVFSRTLEVLEDEEAAKLWVQQSNRSLGGESPLSLLDTEAGYELVMDTLGRIEYGVVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1F6</accession>
    <name>A0A2S9H1F6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1697</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93696">
        <property type="protein sequence ID" value="PRC93696"/>
        <property type="gene ID" value="S2091_1697"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021313">
        <property type="entry name" value="DUF2909"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11137">
        <property type="entry name" value="DUF2909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="73" mass="8077" checksum="94809FC356182751" modified="2018-07-18" version="1">MRNAPLNNMKIFVAIAFILIIASLGSALIYLMKDKGQSMRTVKALAFRVGFSVALFILILIAYHFGYIQPTGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1K6</accession>
    <name>A0A2S9H1K6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1457</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93848">
        <property type="protein sequence ID" value="PRC93848"/>
        <property type="gene ID" value="S2091_1457"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="70" mass="7942" checksum="21B53B73C7E6429D" modified="2018-07-18" version="1">MTSIVVANKVIKYRVPNVFLANKGDFKKCEDKLMREENPENVFNYVSLFLPRLLESKQAGGNAIINSPKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1M2</accession>
    <name>A0A2S9H1M2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">LcrE: type III secretion regulator YopN/LcrE/InvE/MxiC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1466</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93857">
        <property type="protein sequence ID" value="PRC93857"/>
        <property type="gene ID" value="S2091_1466"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009986">
        <property type="term" value="C:cell surface"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019867">
        <property type="term" value="C:outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050709">
        <property type="term" value="P:negative regulation of protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030254">
        <property type="term" value="P:protein secretion by the type III secretion system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010812">
        <property type="entry name" value="HrpJ-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003520">
        <property type="entry name" value="Invas_InvE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013401">
        <property type="entry name" value="T3SS_LcrE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07201">
        <property type="entry name" value="HrpJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01344">
        <property type="entry name" value="INVEPROTEIN"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02568">
        <property type="entry name" value="LcrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HrpJ" evidence="1">
        <location>
            <begin position="56"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="380" mass="42190" checksum="CC52FA07A44C1FBA" modified="2018-07-18" version="1">MATSITGGSAIVAARVLADIRQKESVKVADDGMAQSADVDDGTPAALQQKLVDMADDMASVATQFRNRRDLENKGAASSDGFERVLDDEAAPKAQKLVEVLAVQNLTMDTLLAQARSLFPDDSDLYLVLKELLKRRQLSALQRKRLEGLLDTVSREADPKKLKGGINCALKARLFGATLSLKASLLRQTYRRFLESDRMPLEDYEDWIASYGYKVRHIVLEFVEESLGTDIRAEDPSCNHLEFSYLLAHMRKLQVLRGADREFVLSLLEKKLTPLYGEEEADWLLLLCSLVRRETPAASLLPQALDATLLSSYTQRSTWLNAVRSAWKRLPPELFELPGGASGGCPEAAAAVCAEVLAVFDQLIDYNYAAELQEQRRLPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1N0</accession>
    <name>A0A2S9H1N0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_1491</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93882">
        <property type="protein sequence ID" value="PRC93882"/>
        <property type="gene ID" value="S2091_1491"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="7"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="148"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC93882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="219" mass="24198" checksum="0C2E780A530532F9" modified="2018-07-18" version="1">MQPYKIRVIIADDHPVIVTGIKNAISVSTIDIMDSARNSTQIIQLLDKGIADVLVTDYAMPGGEFGDGLPLFEFILRRYPNIKIVVITMMDNPGVLRTLIGLGVRCIISKSDDCSHLIPAIHIAKSGGRYFSPTINAILQTLDKFPVGDNKTVNLSKRESEVLRLYLSGMKINDIAQQLHRSKQTVSTQKSNAMKKIGVSSDAYLFKYALEVDRMLSSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1R3</accession>
    <name>A0A2S9H1R3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1492</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93883">
        <property type="protein sequence ID" value="PRC93883"/>
        <property type="gene ID" value="S2091_1492"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="976" mass="109919" checksum="9234747EF3EF3E8F" modified="2018-07-18" version="1">MPVSASHHRAATEIYQNQVHSGASRQIKATGQPGPENMPDEISRFASQIRDVRNSPEFPRTINARQASANMVLQVISLLSQVRPAENISSAIDGSLFPVVGMNLSPLGCGSVPVLGESMLLPFNRTLSTPTGGASYFAEAAPATTPAGVVEWNEKNHIYIVKDESTKGLMIKSLKDFLVTTGQLTEDGGEQFEFFLKQRAVNSALVMAPEQGQQEGVPRTKRESIDDKNRRIGEHIETHCAFETELLDNGGNIKGEVLLLMAQRAENPFRMIYDSNKNIKNPSPEQRGVAIGLNFAADILTIGIKPFISALIANNIRKQHYQQNGDEICATRQDHISFAEVATAIDVGGLSFPSRNKGFSKKPMELMNSAPLPERAAYYSRNRHTGVQRELLMEVKTTAGNSDGGGKIFLKSKGNGEFVTWLPHAARPELLERRVIVDESTMNWRYADKFDAMPLNVEMIEGKNFIILHQQKHELHVNRNQHYEVVVHKEAGVKEYIPVYMEPLSKSWHLKVHNEHPVFRTKQQKIIDRIKVAPEADKSYRAIDNLRPDYYGNGKVFEVRYKDRGISESQSLYEVAEMNGVLAPVRTNTVKGHGVTYEVYDVKNINQKGHPIEWSGDRWLFERPTSVHVAGQLKKAITPELYAKDVDARKLSAPDHQGLRWDANDQAYLKVKNNYVEVNTFISHPNNINRKYIKRQDGSNLYIRFKGDKFHPESLAERISNIKTNGFGGRRFMPEDFLIQAKGGIDNAETRAWATELLSQYNLPPNSLYNDLEFAIHYLEWQQIPEWAARYKVPGLNRINVLDSSGNQKTLRYFHDAPLGSGVEGDVYPDGSDGYLIKIYHSENELSAVSDASEAFSRYYGKGSSELFHNSENVIMRMKKVPGEPLSKVGTLPSDAIQKFDEMLSTLAQKNIYHPDLKPDNILWDKDAKKFNPIDFGVDSNDYSRSLSTDELFDNMQNAAVNCITLIRNNVDVRIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1R7</accession>
    <name>A0A2S9H1R7_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">Flagellar basal-body rod protein FlgC</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_1517</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="4 5">The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Bacterial flagellum basal body</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the flagella basal body rod proteins family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93908">
        <property type="protein sequence ID" value="PRC93908"/>
        <property type="gene ID" value="S2091_1517"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030694">
        <property type="term" value="C:bacterial-type flagellum basal body, rod"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071973">
        <property type="term" value="P:bacterial-type flagellum-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010930">
        <property type="entry name" value="Flg_bb/hook_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006299">
        <property type="entry name" value="FlgC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06429">
        <property type="entry name" value="Flg_bbr_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01395">
        <property type="entry name" value="FlgC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0975">Bacterial flagellum</keyword>
    <keyword evidence="7" id="KW-0966">Cell projection</keyword>
    <keyword evidence="7" id="KW-0969">Cilium</keyword>
    <keyword evidence="7" id="KW-0282">Flagellum</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flg_bbr_C" evidence="6">
        <location>
            <begin position="90"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00025933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF06429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC93908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="144" mass="15173" checksum="0C39D1CF00C4FC62" modified="2018-07-18" version="1">MDYRNAFAISASGMSVEKLRLDVTAANLANIHSGKRVDGTLFQPMQVISTEAGENFSTQFEQLAGAQLHGAQVVGVTTTPTAPHMVYQPGNPDADDKGFVTEPGVNQVTEMVNMASALRAYEANVVAMNAAKTMALKALELGGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H221</accession>
    <name>A0A2S9H221_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Basal-body rod modification protein FlgD</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_1525</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Required for flagellar hook formation. May act as a scaffolding protein.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the FlgD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93916">
        <property type="protein sequence ID" value="PRC93916"/>
        <property type="gene ID" value="S2091_1525"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044781">
        <property type="term" value="P:bacterial-type flagellum organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005648">
        <property type="entry name" value="FlgD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03963">
        <property type="entry name" value="FlgD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1005">Bacterial flagellum biogenesis</keyword>
    <keyword evidence="5" id="KW-0966">Cell projection</keyword>
    <keyword evidence="5" id="KW-0969">Cilium</keyword>
    <keyword evidence="5" id="KW-0282">Flagellum</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00024746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC93916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="137" mass="13974" checksum="15B7718470046277" modified="2018-07-18" version="1">MALDPVTNSTGNANLQAAGISQQDFLKILLTQLTEQDPLKPMDNTQFVAQLAQFSQLEQTQQLADTATTSLATQTASQAIALLGKTVTVSSTSSSGSSTSGSVTSISFSGNAPTLTVTPTSGQALTGVALSQITATH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H289</accession>
    <name>A0A2S9H289_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Nucleotidyltransferase domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_1267</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94094">
        <property type="protein sequence ID" value="PRC94094"/>
        <property type="gene ID" value="S2091_1267"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041633">
        <property type="entry name" value="Polbeta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18765">
        <property type="entry name" value="Polbeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Polbeta" evidence="4">
        <location>
            <begin position="105"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF18765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC94094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="210" mass="23053" checksum="C37C7C4BD861D0B3" modified="2018-07-18" version="1">MGIYTDALFSKTQQRVLALIFGQSQRSFYANEIIGLTASGSGAVQRELARLEEAALVTVRRIGNQKHYQANPDTPIFEELRAIVIKTFGVADVLCSALAPLLPLIDLAFIYGSIAKGSETANSDIDLMVVGKLPSNLQLLETLLPSNVQLGRVVNPTLYTPDEFAQRIHDGKSFIMRVLEQPKIFIKGSEHDIIRLGGTNESGSHRETED</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2D7</accession>
    <name>A0A2S9H2D7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1199</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FrmR/RcnR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94026">
        <property type="protein sequence ID" value="PRC94026"/>
        <property type="gene ID" value="S2091_1199"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003735">
        <property type="entry name" value="Metal_Tscrpt_repr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038390">
        <property type="entry name" value="Metal_Tscrpt_repr_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02583">
        <property type="entry name" value="Trns_repr_metal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005260"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="103" mass="10979" checksum="4DCC5194BF9AD862" modified="2018-07-18" version="1">MSDTPLKVVVGTALNPAQKKDLMHRLARIEGQLRGIQKLIANAAVQSDCDGVAQQMAAARKALDRSFVTLLTSAMVTHTAGAQNVEDATLRAQHLAALLDKFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2V7</accession>
    <name>A0A2S9H2V7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">AMP-binding enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0894</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94273">
        <property type="protein sequence ID" value="PRC94273"/>
        <property type="gene ID" value="S2091_0894"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-binding" evidence="1">
        <location>
            <begin position="53"/>
            <end position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="583" mass="64070" checksum="3457E785E5F64A82" modified="2018-07-18" version="1">MDIAVRSEAWAKLYNDPELGAGNFLFKAFDAYTDTESIFLHLEKPYISPSGASHTSFSLNTLCEVVAQLAAWYVQKDVKQGNYVCLYLGDGIASFLHFLALNSLACVPVLINGNLRPDIAALYADLNRFSVFVHDRETATRWQLDAVFGATRRLDAGFKEGVVVPLADLCKDLWPAPRHADDTIMICHSSGTTGVPKAVLFGHAQFFNGKRERLQSFVEDPSDKLATAMPTTHAAGISYLMTAVLLQLPTLSLNTQTGPMVATLLASFQPTIVTAFPQTYASFAEAGLPDAYFKSIRRFYNTGDSAHEAHIAQLLRLAPDARFTDMFGASELGMSQFFKVSTVGSTTSVRSVGKPAAYAHCAILAPDGKELPDGTPGYFGVHSPTVTPGYYGQPHLTAMTTLNGYWLTSDVGLRMADGEFIHLDRAVDVVDSFIIGKPAYTLLLEEHLLKLRDIFDVTVVGIPRGPTREEALLILVRPNAAANAISAEQILRHTLQCYPFQGMASLPEYCVCIGILEPDFVLPLGSTGKVLKRVIRDNFWAWQREFDEQQRDKLGELLWNQDADLSLLPSLPARSLLEYVMTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2W1</accession>
    <name>A0A2S9H2W1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alpha/beta hydrolase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0929</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94308">
        <property type="protein sequence ID" value="PRC94308"/>
        <property type="gene ID" value="S2091_0929"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022742">
        <property type="entry name" value="Hydrolase_4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12146">
        <property type="entry name" value="Hydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015535740" evidence="1">
        <location>
            <begin position="31"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="domain" description="Hydrolase_4" evidence="2">
        <location>
            <begin position="219"/>
            <end position="444"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="488" mass="52018" checksum="AC945D012134BB57" modified="2018-07-18" version="1">MLKKKMNVAVASIKILAGAAFAFLASAAVAGSSDIKIEPKADTHSIAQEIEGNWGGTLAGTLRLILHVKKSPSGEYTAVMESVDQGNAMIPVDKLEVTADHLILSATTVHGSFDAKWDDKAKAWAGTWTQGQGMPLTLSRTNGDIPRPRRPQEHAIETAPLPYGQQAVTFDGGNANVKLAGTFSTPKGEGPFPAVVLIAGSGPNTRDEGVAGHKVFLVLSDYLTKRGIAVLRYDKRGVDQSTGDYKSATTAEFTSDAEAAFTYLRSRADVDVRHIGLIGHSEGGEIVPAVAANDAKVSFIVLLAGPAIRGDKLLAEQIYLIDKASGVPEDHGTISRKINEEIFTAIAEAANESEAKLKAEAIFDKAVEDHKIFGDVAQTKAAGFSQLSTPWMRYFLSYDPVPALRQVKVPVLALNGSLDLQVPPKDDLAAMRDALSNNKDVTVMELANLNHLFQAASTGSPTEYAVIEETINPIALNVIGDWVSAHTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2Y9</accession>
    <name>A0A2S9H2Y9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0959</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94338">
        <property type="protein sequence ID" value="PRC94338"/>
        <property type="gene ID" value="S2091_0959"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="687" mass="74922" checksum="E9563BE01FF315A9" modified="2018-07-18" version="1">MNQFCIKSFSSQANQKTSTLCTYLTLVLCLFLAGCYSNPVKDTIDHAIQTESRCNAIQEAIPVGPKEQTGKLFDALSVRLVGTCLNACDKKTDENLSLDASEYTKENLEAEFKKQIGAVSANNQSNAEKFDVSVENINVAFGQLVRDFEQLKNANGAVKKQLTGLREVAINGDTTLNNCKKRSDCMMNLAEVLQTDVVQFADLQKSVSTLQESLKKVSPDLVALNNQLTKFKFDYQAPGMDTLIEEYTKLSTTINGLDARLENGKETLERLSSKDFEGAASDLMAFKVYNKVAARMLTVIDGMLSQADHAIDKVDERFFGAINLAVYLEQDKLQKQFDHIFNDVINKGFPTNTAKLAFASAACEKMGLGTADAAQNRSMFTPFLYETLINVQIDLAKDGPLTGDARESALKEAKEKDKSGDTYVNTILSEASDAYVSDIKNNKAPAMVDQVALCSAIEEALTLSNGKDVNTLSVVRQACGQAIVSAIVNKTSNLADSQQAIKAAAAQAASQLDADSAIFKSTLDKVLAAIPKPDVKPDPVCDRIVASVNGTHCTNLNGQLIIEFDASFALGATYDNAIEMNLFKLANVLNLWRYNYSSVHVEGYASHAPPVCSKNLPDQKTRLKCENEKNEAIAKNRAIWAQLILGRRLISKPANISAHGTVDSLSFDAAIDRHIRITLENSSTSQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H302</accession>
    <name>A0A2S9H302_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="10">TonB dependent receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">S2091_0958</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94337">
        <property type="protein sequence ID" value="PRC94337"/>
        <property type="gene ID" value="S2091_0958"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="3 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 10" id="KW-0675">Receptor</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="2 6" id="KW-0798">TonB box</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015411160" evidence="7">
        <location>
            <begin position="32"/>
            <end position="843"/>
        </location>
    </feature>
    <feature type="domain" description="Plug" evidence="9">
        <location>
            <begin position="59"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="8">
        <location>
            <begin position="359"/>
            <end position="841"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC94337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="843" mass="90840" checksum="7C32A54EB61965AB" modified="2018-07-18" version="1">MKQATHAHSKRALISSSIVLGLGLLADPVMALDETIEEDGKKVQRVAITGSAIKRLDAETAAPVDVYTKKDIERTGATTVAELIKSLATIDIYDQGELSGNSPAGSGTATVKMRGLSSRNVLVLLNGRRLPTNAMADGSGAGSAVDVNTIPVSVLERVEILKDGGSAIYGADAVAGVMNFITKKNYEGFEVKTGYGQAAVGDAQEKTASVVYGFGDYDENRFNVLATVDILRRSPVYTANRDITRSADWRRMGGLDGRSGFHPSGNIVGGGQVKPCPPEDVKGSSCRFDYNKSLLTAINGADRVNGMLIGSFKVNSTTRAFTEFIYSENKDHFLSQPAPGNFKMNGKTVAGRFMQIGPRTTDRKGSLAQFTVGLEGSNFDIDWDVAIGRGQTKVSNSDSNYMDKGLFYKAIDNGWIDPTSTTNSEAEINKFRIRPYREATSKLTFINAKASAPIMPLAGGSLAYAVGFSVNKEALEDTPDFNQINDNVFGGIRQAAVNASRTSSGVFGELSIPFHKNVEAQVAARYDNISNVGSKTSPKVAIRYQPLPSLMLRASYAGSFLAPTLKQMFGGQEAGAETTENKIICAVFSPISGACEPFSYSRVSGSNLNLKPETGKTFNFGVVIEPISAVSIGVDYFRINKKNEIGKPSVFQALKNGHFGVVNGEAQIYMTNQNMASTDVEGFDIDLRYKTGSTPLGKITVRNTTTWYTKTNSQEIAGEDMGKYLGTFANPKYRNVITASLDNDEWNATASVRTVGGMIDFASSLDNIPPGTRFIPAHSELDVMGQYTGLKNLTFTGGVKNLMDKMPPYSDMGTLGQYGSGGFAQLYSPRGRYLYVGLNYKFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H306</accession>
    <name>A0A2S9H306_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Pro-kumamolisin, activation domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_0982</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
        <text evidence="6">Binds 1 Ca(2+) ion per subunit.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94361">
        <property type="protein sequence ID" value="PRC94361"/>
        <property type="gene ID" value="S2091_0982"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04056">
        <property type="entry name" value="Peptidases_S53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11377">
        <property type="entry name" value="Pro-peptidase_S53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007280">
        <property type="entry name" value="Peptidase_C_arc/bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015366">
        <property type="entry name" value="S53_propep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030400">
        <property type="entry name" value="Sedolisin_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04151">
        <property type="entry name" value="PPC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09286">
        <property type="entry name" value="Pro-kuma_activ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00944">
        <property type="entry name" value="Pro-kuma_activ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="SSF52743"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51695">
        <property type="entry name" value="SEDOLISIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0106">Calcium</keyword>
    <keyword evidence="3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1 6" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0720">Serine protease</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015398886" evidence="7">
        <location>
            <begin position="27"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S53" evidence="8">
        <location>
            <begin position="200"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="6">
        <location>
            <position position="269"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="6">
        <location>
            <position position="273"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="6">
        <location>
            <position position="473"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="514"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="515"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="528"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="530"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC94361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="659" mass="67955" checksum="A8C4C626613185B8" modified="2018-07-18" version="1">MKFRSNFKMLPLAAMVLASMGVAAHAEPWAPTATKSSQLVPSAVHVAAMQVGAPTHIVVALKVRNKAQLDELTANILAGRTTQTLSSAEFMSRHAPSAAQVQSVVAYLTRSGFRNIKVEPNNMLVSADGTAASVKTAFNTEMHVYNVNGRTAHANTGDVFIPQSLSDTILAVHGLQDVQMAHTMLVKAKPNSVHTLTAVGHNPTDFPLIYNASSLPSATNATIGIITSGNMSPTLADLKTFATNSGYPQPNVSVVTLGSASSSTSGEDEWNMDTQDSLAAAGGTIKQMILYTASTLSDADLTTAYNRVVSDNTAKAINVSLGECESDAQSAGTMASNDLIFQSAVAQGQTFSISSGDSGAYECGGSSTAQSYPASSPYVIAVGGSSVNTTGTTTWASETVWACTSASSCQQSANGGAGGGPSLDETAPSWQISAGVLKGATKRGVPDIALDADPNTGAMVLINGQQTQIGGTSLAAPLFAGFWARVQSMNANALAFPAAKMYQLAAANPTMFHDIVSGSNGGYSAAAGWDYASGYGSLNMANFASVMGGTPPPPPGNVLSSGVPVTGLAEATEGSGLYYSIVVPAGKSSLVIKTTGTVGDDDIYVGKNYKPTLNNFDKYSDNYGDNDSVTYRNPAAGTYYVFVEAYQAFSGVTLTATFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3B6</accession>
    <name>A0A2S9H3B6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1089</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94468">
        <property type="protein sequence ID" value="PRC94468"/>
        <property type="gene ID" value="S2091_1089"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="33" mass="3461" checksum="09DF13EA84CDEAF7" modified="2018-07-18" version="1">MHGATDKAHLAAEVGAGDTDHHVQVQAGFFDKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3F2</accession>
    <name>A0A2S9H3F2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative N-acetylglucosamine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0504</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94501">
        <property type="protein sequence ID" value="PRC94501"/>
        <property type="gene ID" value="S2091_0504"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002731">
        <property type="entry name" value="ATPase_BadF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01869">
        <property type="entry name" value="BcrAD_BadFG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="BcrAD_BadFG" evidence="1">
        <location>
            <begin position="9"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="291" mass="29695" checksum="75FD8B6245B8D483" modified="2018-07-18" version="1">MTNKITYLIGVDGGGTGTRVAVADCNGIELARGSAGPSGLINGADFAWNSILSAITAAFLSVDKAVPAFSQMAIGLGLAGVHNKQWAALFAEKNPGFARLELATDAYTTVLGAHQGCPGGMVAIGTGSVGEALLADGSRCEVGGWGFPCGDEAGGAWLGLRAVNHVQQVVDGRAQGSAFSDAVIKHCGGNRDGLFAWLAAANQGSYAQLAPLVIVHANQEDNPVVEQIMQEAGLEIVKIALALDKTNTLPIALCGGLAKSLEKYLPASLLNRIVPPHGDSAAGALLLIKKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3M7</accession>
    <name>A0A2S9H3M7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glutamine synthetase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0573</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glutamine synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94570">
        <property type="protein sequence ID" value="PRC94570"/>
        <property type="gene ID" value="S2091_0573"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004356">
        <property type="term" value="F:glutamate-ammonia ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006542">
        <property type="term" value="P:glutamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036651">
        <property type="entry name" value="Gln_synt_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014746">
        <property type="entry name" value="Gln_synth/guanido_kin_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008146">
        <property type="entry name" value="Gln_synth_cat_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00120">
        <property type="entry name" value="Gln-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01230">
        <property type="entry name" value="Gln-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54368">
        <property type="entry name" value="SSF54368"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55931">
        <property type="entry name" value="SSF55931"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gln-synt_C" evidence="2">
        <location>
            <begin position="88"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="424" mass="46488" checksum="0C490CED5D7001D1" modified="2018-07-18" version="1">MFADISGYPRGKLMPAGSFAAEAELRIAEAITMQAITGEYSYDPIFPDADPDVRMVPDYSTVRLVPWSGVPRAMAIHDCMQLNGDPCGFAPRVILKQVLERYKAKGLTPVVAPEIEFYLTAPNIDPNLALESPMARGGRPESGQSAYSMNMLNELAPFWDEFRAALDTLGVVTDTWIHESGQSQYEINLMHGDPVEVADQAFLFKYAAKEIAIKHGMNAVFMAKPISGQPGNSMHVHQSIVDAEGKNIFSNADGTESLRFRQFIGGLQTYIPDMMLIYAPFINSYRRFVEGSQAPVNLQWGIDNRTAGLRIPISGPAARRVENRIAGADANPYLVIAASLAAGLAGIEEGLTPSEPIVGNGYDHGHDLARGFQASHAQMVNSTSSRRLLGDDFVTGFVSVKGLEYQHFQNEISAWERRYLVPQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3P4</accession>
    <name>A0A2S9H3P4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NADPH:quinone reductase and related Zn-dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0584</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94581">
        <property type="protein sequence ID" value="PRC94581"/>
        <property type="gene ID" value="S2091_0584"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PKS_ER" evidence="1">
        <location>
            <begin position="10"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="328" mass="34246" checksum="221CC9D947C9353B" modified="2018-07-18" version="1">MKAYVIEQSGGPEVLQLRDIPSIPPSADEVRIRVRAFGLNRAEVYRRAGKMGPIVGQVVPGIEAVGEIIEDVSGIFRVGQRVATVMGGLQFSRNGSYADEVTVLRSNVINLDGTTLSWEELAALPESYLTVWGALGRLIDAVPGQTVLIRGATSSVGQAGVTYAKARGQHVIATTRSAENAARLTAIGADVVIIDTGEIAEQVKAAAPEGVDVVLEVVGAATVRDSLKALKPFGAAVVIGLLGGAPSLDSLHLMNDLPNATSLAFFGSGLLGTSALPLAGAPLKWIADNVASGVIPSLRVQTFDFGDVRRAHSLIESDRALGKLVVRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3W7</accession>
    <name>A0A2S9H3W7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Response regulator containing CheY-like receiver AAA-type ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_0626</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94623">
        <property type="protein sequence ID" value="PRC94623"/>
        <property type="gene ID" value="S2091_0626"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002197">
        <property type="entry name" value="HTH_Fis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002078">
        <property type="entry name" value="Sigma_54_int"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025943">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025944">
        <property type="entry name" value="Sigma_54_int_dom_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02954">
        <property type="entry name" value="HTH_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00158">
        <property type="entry name" value="Sigma54_activat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01590">
        <property type="entry name" value="HTHFIS"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00676">
        <property type="entry name" value="SIGMA54_INTERACT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00688">
        <property type="entry name" value="SIGMA54_INTERACT_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50045">
        <property type="entry name" value="SIGMA54_INTERACT_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Response regulatory" evidence="8">
        <location>
            <begin position="3"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma-54 factor interaction" evidence="7">
        <location>
            <begin position="154"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="6">
        <location>
            <position position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC94623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="447" mass="49127" checksum="50316655A1C2A686" modified="2018-07-18" version="1">MANILIIDDNHSVAIALEVLLSLHDISTVKASSPEQGLAILQHTPVDLVIQDMNFTADTTSGEEGVQLFQQIRQRYPDLPVILLTAWTHLGAAVELIKAGAADYLAKPWDDLRLITTVQNLLELGESNRVLQHKITRERKQKRTLEQSFDLRNFVWQDSATERLLSMACQVARADVPILITGPNGAGKERIAEIIQANSSVKSGPFVVLNCGAIPAELIEAELFGADAGAYTGANKSREGKFEAADGGTLFLDEIGNLPLAGQMKLLRVLETGRFERLGSNKERQVKVRVISATNADLHAMMKAGNFREDLFYRLNLIELRLPSLAERPDDILPLAELFLESGKTLHPLAQSALQHYHWPGNVRELKNKITRACLLCASNEITVQDLGLPLAPSVSNNVSEIELDRATLEAALKNTQGVVSQAATQLGLSRQALYRRMDRLGISRNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H403</accession>
    <name>A0A2S9H403_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 4">Beta-lactamase</fullName>
            <ecNumber evidence="2 4">3.5.2.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_0703</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>a beta-lactam + H2O = a substituted beta-amino acid</text>
            <dbReference type="Rhea" id="RHEA:20401"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:35627"/>
            <dbReference type="ChEBI" id="CHEBI:140347"/>
            <dbReference type="EC" id="3.5.2.6"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the class-C beta-lactamase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.2.6" evidence="2 4"/>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94700">
        <property type="protein sequence ID" value="PRC94700"/>
        <property type="gene ID" value="S2091_0703"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030288">
        <property type="term" value="C:outer membrane-bounded periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008800">
        <property type="term" value="F:beta-lactamase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017001">
        <property type="term" value="P:antibiotic catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046677">
        <property type="term" value="P:response to antibiotic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001586">
        <property type="entry name" value="Beta-lactam_class-C_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00336">
        <property type="entry name" value="BETA_LACTAMASE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0046">Antibiotic resistance</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015511852" description="Beta-lactamase" evidence="5">
        <location>
            <begin position="26"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-lactamase" evidence="6">
        <location>
            <begin position="38"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC94700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="394" mass="43047" checksum="395972244B4587B7" modified="2018-07-18" version="1">MRQNTVNTVKKLSVLACFIAGTSFAAVNTDQPKLQDTVDDAIKPLLQKYNIAGMAIAISFNGENYFYNYGVASKDTKQPVTNATLFEIGSLSKTFTATLASYAQANGQLNLSDPVSKYLPNLRGSSFDKISLLNLGTHTAGNFPLQVPDSVQSYDQLMDYYKHFQSSYKPGTYRTYSNPGVGLLGIVTAKSMNMPFDDAMEKILFPALGMKNSYINVPAEQMGNYAQGYNKADKPVRVNPDILASEAYGVKTNTVDLIRFINANMQQVQLDEKLQNAIVATHTGYFKAGEIIQDLIWEQYPDTAKLKQMVAGNSPTMINEDTAATKLSPPLAPQSNVFLNKTGSTGGFGAYALYVPAKKIGIVILANKSYPNDARVTAAYEILKKLDVQIPANK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4A3</accession>
    <name>A0A2S9H4A3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Succinylglutamate desuccinylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_0002</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94807">
        <property type="protein sequence ID" value="PRC94807"/>
        <property type="gene ID" value="S2091_0002"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007036">
        <property type="entry name" value="Aste_AspA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04952">
        <property type="entry name" value="AstE_AspA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC94807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="325" mass="35172" checksum="83EB242E39242021" modified="2018-07-18" version="1">MQSDFCTNFARGDFSALASSFELAGFNVQQPLAGVVQICEDGETASARMRLLISVGVHGDETAPIEMMALLLEELAKTPQQLAVDLMVMVGNIDAIAQAKRFIDVDLNRLFTPQRTQFNNAQEAQRADQLMHAATQFFDGHQNKWHLDLHTAIRASFYPTFAIVPGKHNPAFVSWLGSAGIAAAVLNPQASVTFSSYTCKHLGAVSCTAELGRIGEMGKNDLSQFVATQAALAALLRSGLSATENTDTAPLVFRVAQELIKRSEAFQLTFDGNTQNFTEFAPNALIATDGELTYVVGAEPEYVLFPNPSVRVGLRAGLMVVRAVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4H2</accession>
    <name>A0A2S9H4H2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0077</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94882">
        <property type="protein sequence ID" value="PRC94882"/>
        <property type="gene ID" value="S2091_0077"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="99" mass="9389" checksum="620E46C08AD24E6E" modified="2018-07-18" version="1">MRELSFVDVEKVNGGIGPGGAVLGALTGAATASAGQHNAGGIVAGAVLGGVAGFFGGIALSGQAGLAGAAMFGGMSVGVAWIGSRFQAGGYRPLAPMLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4I9</accession>
    <name>A0A2S9H4I9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0073</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94878">
        <property type="protein sequence ID" value="PRC94878"/>
        <property type="gene ID" value="S2091_0073"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="58"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="82" mass="10107" checksum="756D995AB5A911F6" modified="2018-07-18" version="1">MYLFLYSTLSTIFTLFVPIFLIHHHAKYRYYKWMFPIMMIYFPLLECLNPNEKEMVDRFWDGAFKAALVLPLTAFFIWKKRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4K4</accession>
    <name>A0A2S9H4K4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Biopolymer transport protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_0104</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the ExbD/TolR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94909">
        <property type="protein sequence ID" value="PRC94909"/>
        <property type="gene ID" value="S2091_0104"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003400">
        <property type="entry name" value="ExbD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30558">
        <property type="entry name" value="PTHR30558"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02472">
        <property type="entry name" value="ExbD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC94909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="146" mass="15955" checksum="FA0E9F4B30B739C8" modified="2018-07-18" version="1">MNFRKGSKRRAEPEINLIPFIDVLLVILIFLMVTTTYSRFTELQINLPTADANVAQQRPNEIQIGVDSRGNYKINQKPISKIDVADLAENLKKAASELAVGTGQTEPIVVINADGSASHQSVIDILEAARLAGLSKITFAAQSHEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4N4</accession>
    <name>A0A2S9H4N4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="11">GGDEF: diguanylate cyclase (GGDEF) domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">S2091_0096</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94901">
        <property type="protein sequence ID" value="PRC94901"/>
        <property type="gene ID" value="S2091_0096"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01948">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001633">
        <property type="entry name" value="EAL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035919">
        <property type="entry name" value="EAL_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007895">
        <property type="entry name" value="MASE1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00563">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05231">
        <property type="entry name" value="MASE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00052">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141868">
        <property type="entry name" value="SSF141868"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50883">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="32"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="59"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="82"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="111"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="151"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="184"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="223"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="260"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="7">
        <location>
            <begin position="304"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="8">
        <location>
            <begin position="394"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="10">
        <location>
            <begin position="608"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="domain" description="EAL" evidence="9">
        <location>
            <begin position="755"/>
            <end position="1009"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC94901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="1009" mass="112675" checksum="5C56E41DC7091269" modified="2018-07-18" version="1">MLRERTMLLKIIFLSLVYFMAGWLGLQIPYAGTHITLVWLPTGIAVASLLLWGRSVWPGIFLGAVLVNFSIGSTWLLASGIAVGNTLAPLLTVALLRRSEFHAVFDRKKDVGTFILAACLGMLVSASSGVLQLNLGGLLPVHAMGSAWLSWWMGDVIGVLLAAPVLLTLNQHNINRLAQERKELLLWFFIALPIGWLTFIHNFQGIGQTLPLAFLTLPLFAWAALRFGVTGSGLAVLGFSILAAWGTATQHGNFFLPDAHVSLFLLWSYMTSAALTGLLITALQAERIVVEDTLLKNEKQLNELTQSRQAILDGTNFSVISTDPFGVIQIFNQSAERMLGYLSEEMVGKKSPTIFHDHDEMLKRASELTIELGIYVEPNFDAFVAKARILRVPDEHEWTYIRKDGFRFPVLLSVTALVNKLDEVIGYLGVGIDRSEYHQQRNRIRDSDELFRVLYESSSEAHMLTTRDKGFIGANSAAIKLFGCHDLEQFLKLSPATTSPEFQHDGRRSDEKAQEMMSLSLDGGSHTFEWLHQRVDGTIFFAEVLLTRINIGGENILHATVRDITLRKAADEEISKLAFYDALTGLPNRRLLMDRLKQAMANSKRSGREGALMFIDLDHFKNLNDTLGHDIGDVLLQQVAKRLSLCVREIDTVARLGGDEFVVMLNNLSENFNKAAEQVEKIGGKILSTLNQPYLLNGHSHRNTSSIGVTLFSNCKGIISELLKQADLAMYQAKASGRNNFQFFDSKIQDVVNAHVALEIELRHGLSSDEFVLHFQPQVDRENRVIGVEVLIRWQHATRGLILPAEFIPLAENIGLIIPLGLWALETACAQLAVWEKQPERSHLTIAVNVSTIQFCAVNFVEQVIAVIDRTGADPHKLKLEITESILLDNVENIIKKMLTLQSYGISFALDDFGTGYSSLSYLKRLPVSQLKIDRSFVRDVLTDPNDAIFARTIITLGQCLGLVVMAEGVETEEQRQFLFEHDCNAFQGYFFSRPLPLIDFEQFLDQNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4R4</accession>
    <name>A0A2S9H4R4_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_0153</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94958">
        <property type="protein sequence ID" value="PRC94958"/>
        <property type="gene ID" value="S2091_0153"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004673">
        <property type="term" value="F:protein histidine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Histidine kinase" evidence="3">
        <location>
            <begin position="198"/>
            <end position="427"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC94958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="427" mass="46438" checksum="9745CB0E2DB5FD98" modified="2018-07-18" version="1">MAFKFGIPTRFRITVYVITLMGLAAFAAQNSHAPRLIVTCGLLALLITEMLRRALHTLERQSQRPAQEIAVAIPLHQQTLAANLLTLEAHLEHAPIALFCGSQSAGNELVTPLNTYARRLIAPGRVSNLPSFYAKLAASDNGQRNIINFDTERGQERALVSINNIHIHGAAQRLIAILPIESELETVAFNAWQQLVHVLTHEIMNSLTPVASLSRTAHDLLAEMREKIGATIAEKTHAELIDAQEIGNDLSTALDAISRRSDSLVGFVSNYRSLTNVPTAAPERVRIQQLFSRLAALVDPAWQAGGGKATFTVEPTSLELMIDSGQLEQALINLLRNAAEATADVKNRAVTVNARLTRGSRLRIEISDNGPGVPESLIPHIFTPFFTTKTKGSGIGLAMVRQLVHGNGGTVRYVKAANQGARFILTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4U7</accession>
    <name>A0A2S9H4U7_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peptide chain release factor 3</fullName>
            <shortName evidence="5">RF-3</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">prfC</name>
        <name evidence="8" type="ORF">S2091_0182</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94987">
        <property type="protein sequence ID" value="PRC94987"/>
        <property type="gene ID" value="S2091_0182"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016149">
        <property type="term" value="F:translation release factor activity, codon specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006449">
        <property type="term" value="P:regulation of translational termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04169">
        <property type="entry name" value="RF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3280">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00072">
        <property type="entry name" value="Rel_fac_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004548">
        <property type="entry name" value="PrfC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032090">
        <property type="entry name" value="RF3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038467">
        <property type="entry name" value="RF3_dom_3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041732">
        <property type="entry name" value="RF3_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43556">
        <property type="entry name" value="PTHR43556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16658">
        <property type="entry name" value="RF3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="SSF54980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00503">
        <property type="entry name" value="prfC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="7">
        <location>
            <begin position="30"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="39"/>
            <end position="46"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="107"/>
            <end position="111"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="161"/>
            <end position="164"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC94987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="553" mass="61188" checksum="E290C7A293572322" modified="2018-07-18" version="1">MSDQIPPTSPISPNTAGSTSATALVNKEVARRRTFGIISHPDAGKTTLTEKLLMFSGAIQLAGTVKGRKSGRHATSDWMDIEKQRGISVASSVMQFDYKGHVVNLLDTPGHQDFSEDTYRVLTAVDSALMVIDAAKGVEEQTLKLLNVCRMRNTPIITFVNKMDRETRDPLELLDELESVLKIQCAPVTWPIGMGKNFRGVYHILRDEIMLFTAGNDRADQEFEVLKGIDNPRLAAMFPLEIEQLKMEVELVHGASHPFDLNAFLAGTQTPVFFGSAINNFGVREILNALIEWAPAPRSRDATVRSVEPTEAPFSGFVFKIQANMDPAHRDRIAFLRVCSGHFERGMKLKHLRLNREVKVSSVVTFMASSREQVEEAFAGDIIGLPNHGNMQIGDSFSEGELLQFTGIPYFAPDFFRSVRIRNPLKIKQLHKGLQQLGEEGAVQVFKPINNSDLVLGAVGVLQFEVVASRLLNEYGVDAVFEGTSISSARWVSCDDKKIMNDFQNSSAGHNLAHDAAGNLAYLATSGVNLKLTQERWPQVVFHATREHAAKLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H500</accession>
    <name>A0A2S9H500_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nitroreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0260</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95065">
        <property type="protein sequence ID" value="PRC95065"/>
        <property type="gene ID" value="S2091_0260"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.109.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029479">
        <property type="entry name" value="Nitroreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000415">
        <property type="entry name" value="Nitroreductase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00881">
        <property type="entry name" value="Nitroreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55469">
        <property type="entry name" value="SSF55469"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nitroreductase" evidence="1">
        <location>
            <begin position="14"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC95065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="226" mass="25847" checksum="2BDA2D082488768D" modified="2018-07-18" version="1">MIETEEQKIVDEVIASRRSIRAFLPTPVARDEIQKIIEIAARAPSGSNTQPWKVYVLIGEVKQQLSDEILQAHNNPHSAYKEEYHYYPVQWLSPYLERRRKIGWDLYSLLGLGRENKAGMHAQHGRNFIFFDAPVGIIFTIDRVMQQGSWLDYGMFLQNIMLAAKARGLDTCPQAAFTQYHQIIHKTLNLSDQEMVVCGMSLGYADTTKIENTLVTERGTSIVKFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H503</accession>
    <name>A0A2S9H503_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Efflux transporter, RND family, MFP subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_0151</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94956">
        <property type="protein sequence ID" value="PRC94956"/>
        <property type="gene ID" value="S2091_0151"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006143">
        <property type="entry name" value="RND_pump_MFP"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01730">
        <property type="entry name" value="RND_mfp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="27"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="149"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC94956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="428" mass="47077" checksum="51E63955E2F7971B" modified="2018-07-18" version="1">MNHPKTPYAVSGSAMDTVVRKSYRKQIIALSVGAVCVVALAISLWRWMPHGLQVEASELRMAVVERGIFLDEMVVRANATPLNSVILDAVESGRVEEVFVRDGTVVTQGTPLFRLSNPQRQIELLARQSDQATQISNISNLRAALAVSITDHERRLSDLQFNFQQAEKKNIRNKQLADKGFISGVALEESEDQLEQQRHVLSQEQSRSNEEMEIKRGGIAQMEQANARLASGLTLLNATIDALTVRAPTSGRLTDFHLQVGEAVAPNQHIGRIDDPVRYKLSAAVDEYYLNRVTANRQGKAQLNDQVFPVEVSRVYPQIDKGQFKIDMVFKAEQPAQLNPGQSLDTQIVLGDPKPALLLPTGAFINDSGGAWVFVVSPNGTTAERRMVKIGRRSNSQIEVVAGLAAGEKVIVSSYTGFGQATRLQLNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H529</accession>
    <name>A0A2S9H529_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Galactose oxidase, central domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0284</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95089">
        <property type="protein sequence ID" value="PRC95089"/>
        <property type="gene ID" value="S2091_0284"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="SSF117281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="178"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC95089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="485" mass="50446" checksum="F01E48D21ACCFCE1" modified="2018-07-18" version="1">MSAIKVNRVLIAAAVAVFLLVGCKGKGSSSSSSIPASLTNWTWEAGTNVANSIGSAGAQGVPSALNQPAGRSGSMNWQDTKGQFWVFGGSGVNNSIYNDMWVLSPSTLQWTWMAGSTSGTTTGTATTTNAPGSRNSAATWMDASGNFWMFGGYGTDSNGLTGYLCDMWMFNPTTNTWTSEGGSPTGGGSASPAPSFGTINVPATSNLPNPRSNAAYWTETNPTTGAITFWMFGGQGYLNNTSGVQNDLWTFNPSTKEWTWVGGSSTLLNVAGIYGTAGTPAATNQPGSRQSATTWTQTTAGVTTLWMFGGTGIDGSTISLNGQLNDLWSFNTSTGVWTWVNNGTNPTNVANSIGVYGTNDVAAPTNVPGGRSGATGWTDTSGNRWLFGGYGINSSGTLTILNDLWEFQINSTGGGQWVWINGSYNGSATGYYGSPGVLSSSNMPGSRYAASGWTDSAGNFWLFGGTGFDAAGVNGRLSDMWKFVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5C2</accession>
    <name>A0A2S9H5C2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">TonB-Xanth-Caul: TonB-dependent receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_0385</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95190">
        <property type="protein sequence ID" value="PRC95190"/>
        <property type="gene ID" value="S2091_0385"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010104">
        <property type="entry name" value="TonB_rcpt_bac"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01782">
        <property type="entry name" value="TonB-Xanth-Caul"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0675">Receptor</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015560790" evidence="2">
        <location>
            <begin position="41"/>
            <end position="911"/>
        </location>
    </feature>
    <feature type="domain" description="Plug" evidence="3">
        <location>
            <begin position="72"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC95190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="911" mass="98256" checksum="0B6A169A3A66B26F" modified="2018-07-18" version="1">MKIFTTKRSQVSGLNSVIFKISPIAAGCAILLSTAGSVYAQQADKDQQADASANTVVVTGIRSGIENAISVKRDSTSIVEAISAEDIGQLPDQSIAESIARLPGVAAQRVAGRAQTISIRGLSPDFASTTLNGREQATTGDNRAAEFDQYPAELFGGVVIYKTPDAALIDQGLSGTIDMQTFDPLAFPGRTVSMNVRGEKNSLGPIANSSDKGNRFSINYIDQFADRTIGIQIGVAHLQSPRNDHETGLYEPWSVNQLPGTPANTSEMNGIKSLATSGTTKRDGLVSTLEWKPNKDFTSKVDLFYSKFSEITTANQWEENLSWGGGNNPSPVFTSANASNGVLNGGTLSGVYPLVRGEYNDREDNIKSLGWGNTMKFDGWKLLADLNYSKAVRNENYHEMNTQLITATGGPVLDTSNVNWATGGFPTMNGGLNYSNPNTLYLNNTIYGEGSGHAPHTDDTVKGFKLVATINAPKSIGDWVSDFNVGADYTDHIKNHSNLQGNQNLIAPNGVVISPGLLYSPVNLGFSGTGTIPSFNVPGIMAQYFQPFNPDPNAPQNVAAEWSVTEKIATTFVKANLDHQLSSSINLRGNIGLQVQGTKQSSTGEVGFNNEVTPTTVGKSYTDVLPQMNLVFELPDNEVIRFAAGKQVMRPRLDDLNSGFNFSVATSTQIPSGNGGNPQLNPWRANSVDLAFEKYFGKKAYVSAAMYYKKLTSYIYDESNLYNFSQWTPGTIAITNTGFYSSQYNGQGGSIEGLELTSSLPLDMLTPSLKGFGLQASTGLNNSAITVKSSTFDVGSAIPLPGMSKHVASLTAYYEMSGFSARIGARYRSEFVGDIENFSGNRNLRFIAPETIVDAQIEYTFQEGTYKDLGLFLQLGNLTNAAYKTYQGTPNQPLEYEKYGSTLLAGLNYKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5L7</accession>
    <name>A0A2S9H5L7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Short-chain alcohol dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0475</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95280">
        <property type="protein sequence ID" value="PRC95280"/>
        <property type="gene ID" value="S2091_0475"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC95280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="248" mass="25991" checksum="262BBE6202CE2A9A" modified="2018-07-18" version="1">MIVLITGASSGFGEAMARRFVQGGHRVIAAARRSDKLAALAAELGAALLPITLDVTQTDTIPAALAALPAEWQAIDVLINNAGLALGTAPAQQASLLDWDTMISTNNRGLVHMTHAVLPGMVARRSGLVMNLGSVAGSYAYPGGNVYGASKAFVDHFTLNLRADLAGTGVRATNIAPGLCGGTEFSQVRYKWDEAAAAKVYQGTQPLTAQDIAETAYWIATLPSHININNIELMPVCQSFAGMAITRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5M7</accession>
    <name>A0A2S9H5M7_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Aspartate/glutamate leucyltransferase</fullName>
            <ecNumber evidence="4">2.3.2.29</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">bpt</name>
        <name evidence="7" type="ORF">S2091_0485</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>L-leucyl-tRNA(Leu) + N-terminal L-aspartyl-[protein] = H(+) + N-terminal L-leucyl-L-aspartyl-[protein] + tRNA(Leu)</text>
            <dbReference type="Rhea" id="RHEA:50420"/>
            <dbReference type="Rhea" id="RHEA-COMP:9613"/>
            <dbReference type="Rhea" id="RHEA-COMP:9622"/>
            <dbReference type="Rhea" id="RHEA-COMP:12669"/>
            <dbReference type="Rhea" id="RHEA-COMP:12674"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:64720"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78494"/>
            <dbReference type="ChEBI" id="CHEBI:133042"/>
            <dbReference type="EC" id="2.3.2.29"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>L-leucyl-tRNA(Leu) + N-terminal L-glutamyl-[protein] = H(+) + N-terminal L-leucyl-L-glutamyl-[protein] + tRNA(Leu)</text>
            <dbReference type="Rhea" id="RHEA:50412"/>
            <dbReference type="Rhea" id="RHEA-COMP:9613"/>
            <dbReference type="Rhea" id="RHEA-COMP:9622"/>
            <dbReference type="Rhea" id="RHEA-COMP:12664"/>
            <dbReference type="Rhea" id="RHEA-COMP:12668"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:64721"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78494"/>
            <dbReference type="ChEBI" id="CHEBI:133041"/>
            <dbReference type="EC" id="2.3.2.29"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the R-transferase family. Bpt subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.29" evidence="4"/>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95290">
        <property type="protein sequence ID" value="PRC95290"/>
        <property type="gene ID" value="S2091_0485"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004057">
        <property type="term" value="F:arginyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008914">
        <property type="term" value="F:leucyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071596">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process via the N-end rule pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00689">
        <property type="entry name" value="Bpt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017138">
        <property type="entry name" value="Asp_Glu_LeuTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030700">
        <property type="entry name" value="N-end_Aminoacyl_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007472">
        <property type="entry name" value="N-end_Aminoacyl_Trfase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007471">
        <property type="entry name" value="N-end_Aminoacyl_Trfase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21367">
        <property type="entry name" value="PTHR21367"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04377">
        <property type="entry name" value="ATE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04376">
        <property type="entry name" value="ATE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037208">
        <property type="entry name" value="ATE_pro_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="1 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ATE_N" evidence="5">
        <location>
            <begin position="21"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="domain" description="ATE_C" evidence="6">
        <location>
            <begin position="110"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04377"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC95290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="241" mass="27768" checksum="20F3FAEF57D8EC9B" modified="2018-07-18" version="1">MTKLNDLPLNTIQFYATAPYTCSYLDDRLARSQVATPAHFINADVYSALVKSGFRRSGEFTYRPYCDECHACVPVRVCVAEFTPNRSQRRAFALHAGLVTTVCDLSYVAEHYDLYQRYQQARHAGGGMDQDSRDQYVQFLLQSRVDTRLVEFRDADNVLKMVSLIDILDDGFSSVYTFYEPDISASYGTYNVLWQIEQVKSVGLPYLYLGYWISETGKMAYKSNFRPFEAYINDEWKLHSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GS89</accession>
    <name>A0A2S9GS89_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">ORF6N domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_4699</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000046">
        <property type="protein sequence ID" value="PRC90592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90592">
        <property type="protein sequence ID" value="PRC90592"/>
        <property type="gene ID" value="S2091_4699"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018873">
        <property type="entry name" value="KilA-N_DNA-bd_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10543">
        <property type="entry name" value="ORF6N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ORF6N" evidence="3">
        <location>
            <begin position="19"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="180"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="123"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF10543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC90592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="201" mass="22690" checksum="9EEC825AD72D70C7" modified="2018-07-18" version="1">MSASKIIPAPVPLTQIEGRILIIRGQKVIIDADLAQLYGVPTKRLNEQVKRNKERFPADFMFALTQEEKAEVVANCDHLAKLKFSATLPFVFTEHGAIQAANVLASPQAIEMGVYVVRAFVRLREMIVAHKELALRLDDLENKAELMALKHDTFEHNTRVQLKQVFEAIRELMTPPEPIKKRPIGFITPEDTQTKPKAAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSH2</accession>
    <name>A0A2S9GSH2_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Lipoyl synthase</fullName>
            <ecNumber evidence="6">2.8.1.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Lip-syn</fullName>
            <shortName evidence="6">LS</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Lipoate synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Lipoic acid synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Sulfur insertion protein LipA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">lipA</name>
        <name evidence="8" type="ORF">S2091_4611</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>[[Fe-S] cluster scaffold protein carrying a second [4Fe-4S](2+) cluster] + 4 H(+) + N(6)-octanoyl-L-lysyl-[protein] + 2 oxidized [2Fe-2S]-[ferredoxin] + 2 S-adenosyl-L-methionine = (R)-N(6)-dihydrolipoyl-L-lysyl-[protein] + 2 5'-deoxyadenosine + [[Fe-S] cluster scaffold protein] + 4 Fe(3+) + 2 hydrogen sulfide + 2 L-methionine + 2 reduced [2Fe-2S]-[ferredoxin]</text>
            <dbReference type="Rhea" id="RHEA:16585"/>
            <dbReference type="Rhea" id="RHEA-COMP:9928"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="Rhea" id="RHEA-COMP:10475"/>
            <dbReference type="Rhea" id="RHEA-COMP:14568"/>
            <dbReference type="Rhea" id="RHEA-COMP:14569"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="ChEBI" id="CHEBI:29919"/>
            <dbReference type="ChEBI" id="CHEBI:33722"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:78809"/>
            <dbReference type="ChEBI" id="CHEBI:83100"/>
            <dbReference type="EC" id="2.8.1.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="6">Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="pathway">
        <text evidence="6">Protein modification; protein lipoylation via endogenous pathway; protein N(6)-(lipoyl)lysine from octanoyl-[acyl-carrier-protein]: step 2/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the radical SAM superfamily. Lipoyl synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.8" evidence="6"/>
    <dbReference type="EMBL" id="PUGF01000039">
        <property type="protein sequence ID" value="PRC90661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90661">
        <property type="protein sequence ID" value="PRC90661"/>
        <property type="gene ID" value="S2091_4611"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00538">
        <property type="reaction ID" value="UER00593"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016992">
        <property type="term" value="F:lipoate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102552">
        <property type="term" value="F:lipoyl synthase activity (acting on glycine-cleavage complex H protein"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102553">
        <property type="term" value="F:lipoyl synthase activity (acting on pyruvate dehydrogenase E2 protein)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009249">
        <property type="term" value="P:protein lipoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00206">
        <property type="entry name" value="Lipoyl_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031691">
        <property type="entry name" value="LIAS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003698">
        <property type="entry name" value="Lipoyl_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10949">
        <property type="entry name" value="PTHR10949"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16881">
        <property type="entry name" value="LIAS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005963">
        <property type="entry name" value="Lipoyl_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00271">
        <property type="entry name" value="lipoyl_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00510">
        <property type="entry name" value="lipA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6" id="KW-0408">Iron</keyword>
    <keyword evidence="5 6" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Radical SAM core" evidence="7">
        <location>
            <begin position="98"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="86"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="91"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="97"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="112"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="116"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="119"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="326"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC90661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="337" mass="37198" checksum="89BC37C91210F7BF" modified="2018-07-18" version="1">MAVEMNLETTEVTNAATNEAPKPAKTVAGVKLRGAEKMARIPIKIIPTEPSQYLRKPSWIRAEFTGTEEVARIKSILRENKLHTVCEEARCPNLGECFKSGTATFMIMGDICTRRCPFCDVGHGRPNPLDTEEPANLAKTVSAMGLRYVVITSVDRDDLRDGGATHFAECIRAIRLATPATKIEVLTPDFRGRVDVALNILNNDVPDVFNHNLETVPRLYKEARPGADYQNSLTLLQRFGQENPTVPTKSGLMLGLGETIPEVQQVLQDMRAHGVAMLTLGQYLQPSPHHLAVQRYVTPAEFEELRIYALSIGFDQVASGPMVRSSYHADLQAIGAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GST2</accession>
    <name>A0A2S9GST2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Flagellar hook-length control protein FliK</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_4530</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Controls the length of the flagellar hook.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FliK family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000036">
        <property type="protein sequence ID" value="PRC90782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90782">
        <property type="protein sequence ID" value="PRC90782"/>
        <property type="gene ID" value="S2091_4530"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009424">
        <property type="term" value="C:bacterial-type flagellum hook"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044780">
        <property type="term" value="P:bacterial-type flagellum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001635">
        <property type="entry name" value="Flag_hook_Flik"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021136">
        <property type="entry name" value="Flagellar_hook_control-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038610">
        <property type="entry name" value="FliK-like_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02120">
        <property type="entry name" value="Flg_hook"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01007">
        <property type="entry name" value="FLGHOOKFLIK"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1005">Bacterial flagellum biogenesis</keyword>
    <keyword evidence="6" id="KW-0966">Cell projection</keyword>
    <keyword evidence="6" id="KW-0969">Cilium</keyword>
    <keyword evidence="6" id="KW-0282">Flagellum</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flg_hook" evidence="5">
        <location>
            <begin position="340"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="117"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="187"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="236"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="120"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC90782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="467" mass="46007" checksum="2EAFB1DA04CEF1D2" modified="2018-07-18" version="1">MHATIPTAPSSPITVQNSGTASAANKSASGDSFNQVLSNEMNAQAPAKAPATSSSASPASNASSSAPATGKKNSTATTAPSTPTQPANQSSSATDTQANAAAALTAAAVAAAAAAASASVVPTNPINSTTATSDATSTASTASTANAAILASSAAAIPTSFTPVAPPPASNTKAPVASNLINATTTKTAGTPIPAQTAPTANQTKVTGSLSQNLSPQPGLFSSSLKAAQFAQTAPAVNSNAATSATAPSATETTEPAPTVTVPTVANSSASAAALTNAAINTSLQVQTLKTANQGLNATQLSAIAPVLTLPTTTNAMDATSSNAIAPPVGTPNWEQAVGQKISWMAVGGQQSASLTLNPPDLGPLQVVLSVNNQHVSATFISHQPEVRAALESAIPKLREMMGQSGIQLGECNVSSQTKQQQEFAQRQSNSTNSINSTNSSVSTVGLTQLNQSDGGRGGIGLVDTFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSV1</accession>
    <name>A0A2S9GSV1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Pyridoxal-dependent decarboxylase conserved domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_4465</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 3 4">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the group II decarboxylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000035">
        <property type="protein sequence ID" value="PRC90802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90802">
        <property type="protein sequence ID" value="PRC90802"/>
        <property type="gene ID" value="S2091_4465"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016830">
        <property type="term" value="F:carbon-carbon lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019752">
        <property type="term" value="P:carboxylic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002129">
        <property type="entry name" value="PyrdxlP-dep_de-COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00282">
        <property type="entry name" value="Pyridoxal_deC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0456">Lyase</keyword>
    <keyword evidence="3 4" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="3">
        <location>
            <position position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR602129-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC90802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="196" mass="21608" checksum="88B096490F14313C" modified="2018-07-18" version="1">MLKGVEHADSWSTDGHKWLNVPYDSGFAFVAHPEAHRNAMSYEASYISHNDLVREQKDWNAEWSRRGRGVATYAALRQLGRQGVAALIDSSCEAAHALVTGIAALPGAQLMWEPQINQGLVRFLDLSPEATESDHDRWTDAVTSAVVASGEALFSNTTWRGKRCMRVSVCNWQTSAKDVARAVAAVERVLRAKSVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSY4</accession>
    <name>A0A2S9GSY4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">KWG Leptospira</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4486</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000035">
        <property type="protein sequence ID" value="PRC90823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90823">
        <property type="protein sequence ID" value="PRC90823"/>
        <property type="gene ID" value="S2091_4486"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032774">
        <property type="entry name" value="WG_beta_rep"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14903">
        <property type="entry name" value="WG_beta_rep"/>
        <property type="match status" value="9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015636917" evidence="1">
        <location>
            <begin position="21"/>
            <end position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="398" mass="43562" checksum="50F6B39E55A8F3D8" modified="2018-07-18" version="1">MKKISFLFIGIFLTISIAQSQNIKAQSKTVALQYKPLTNDTYDNATDFYEGLAAVKINNKWGFIDSSGKMVIEPQFNPGQAQFNSYFSEGLAAINFTAAKTSVTNANDPPNTQWGFADKNGKVVIQPKFSGNYYAPPRFSNGLAVIGASFIGTTIATFGLRTKYGYINKAGAFAIPAKFDEASDFSEDLASVRIGDKYGFIDTSGRVVIEPTYDSPSYFKDGIAIVEVNNVSFMIDKKNKKIVDKGFPGLSAFSDGLARFEENGKVGFIDKKGDVKIKPTLDFGLEKSKQMMYFSEGLCQIELGKNPATDSPSWIAGKFGYINKEGKMVINPQFDHVGPFKNGIAVASMYGKYGYINKSGEFVIPPIFANAGYFVDGVARVSGGSSFGDYKYRFIKLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSZ9</accession>
    <name>A0A2S9GSZ9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glyoxalase-like domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4481</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000035">
        <property type="protein sequence ID" value="PRC90818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90818">
        <property type="protein sequence ID" value="PRC90818"/>
        <property type="gene ID" value="S2091_4481"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041581">
        <property type="entry name" value="Glyoxalase_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18029">
        <property type="entry name" value="Glyoxalase_6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="71"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="199"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="327" mass="35420" checksum="65FDE09667004164" modified="2018-07-18" version="1">MYAQDNSIPTDAIPANKDRQRRVSTCRKLGFFKHNILAAFIGAAIAMPALSADLSFPALVTPASQEHHVGKIVFVELVTPNLVASKQFYGGLFGWTFRDIHTGGREYVEASMDGRPVAGLIYKAIGENEHKQPAWLSFIAVSDVDAAKRMAVEHGAKVLFEPHNIPNRGREAVFADPQGAVFAILASSSGDPADVIAAPGEWIWSSLITVDPGADAAFYQTLFNYEVFDLPAAQGFQHLMLASDDYARASINSLPADKAITPPHWLNYVRVDDTVKMAAKVVALGGKILVAPRIDRHGGKVAVVADTSGAPFGLIEWPNTERKEVMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GT67</accession>
    <name>A0A2S9GT67_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">Kynureninase</fullName>
            <ecNumber evidence="4 5">3.7.1.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">L-kynurenine hydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">kynU</name>
        <name evidence="7" type="ORF">S2091_4403</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4 5">Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>3-hydroxy-L-kynurenine + H2O = 3-hydroxyanthranilate + H(+) + L-alanine</text>
            <dbReference type="Rhea" id="RHEA:25143"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:36559"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="ChEBI" id="CHEBI:58125"/>
            <dbReference type="EC" id="3.7.1.3"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4 5">
            <text>H2O + L-kynurenine = anthranilate + H(+) + L-alanine</text>
            <dbReference type="Rhea" id="RHEA:16813"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16567"/>
            <dbReference type="ChEBI" id="CHEBI:57959"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="EC" id="3.7.1.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4 5">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4 5">Amino-acid degradation; L-kynurenine degradation; L-alanine and anthranilate from L-kynurenine: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4 5">Cofactor biosynthesis; NAD(+) biosynthesis; quinolinate from L-kynurenine: step 2/3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 5">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 5">Belongs to the kynureninase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.7.1.3" evidence="4 5"/>
    <dbReference type="EMBL" id="PUGF01000033">
        <property type="protein sequence ID" value="PRC90910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90910">
        <property type="protein sequence ID" value="PRC90910"/>
        <property type="gene ID" value="S2091_4403"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00253">
        <property type="reaction ID" value="UER00329"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00334">
        <property type="reaction ID" value="UER00455"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061981">
        <property type="term" value="F:3-hydroxykynureninase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030429">
        <property type="term" value="F:kynureninase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034354">
        <property type="term" value="P:'de novo' NAD biosynthetic process from tryptophan"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043420">
        <property type="term" value="P:anthranilate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097053">
        <property type="term" value="P:L-kynurenine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019805">
        <property type="term" value="P:quinolinate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006569">
        <property type="term" value="P:tryptophan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01970">
        <property type="entry name" value="Kynureninase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010111">
        <property type="entry name" value="Kynureninase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14084">
        <property type="entry name" value="PTHR14084"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038800">
        <property type="entry name" value="KYNU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01814">
        <property type="entry name" value="kynureninase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 4 5" id="KW-0662">Pyridine nucleotide biosynthesis</keyword>
    <keyword evidence="3 4 5" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminotran_5" evidence="6">
        <location>
            <begin position="79"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="region of interest" description="Pyridoxal phosphate binding" evidence="4">
        <location>
            <begin position="129"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="97"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="98"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="172"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="201"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="204"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="226"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="256"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="282"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="4">
        <location>
            <position position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR038800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC90910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="414" mass="45669" checksum="7F33A930C5F85096" modified="2018-07-18" version="1">MITKSHCQTLDQNDALAPLRNEFDLPKNVTYLDGNSLGAQPKAALTRAQQVITQEWGQDLIRSWNSAGWFDMPSRLGDMLAPLIGANPAEVVVTDSTSVNLFKALAAALHLQAELHPHKKIIVSERSNFPTDLYMVQGLTQWLDRGYRLELVDSPEQLNSAINEHVAVALLTHVNYRTGEMLDMTSLTTHIHAQGALAIWDLCHSAGAVPVELNAANADFAIGCTYKYLNGGPGSPAFIWVAERHLAKFTHPLSGWWGHTAPFAMQPEFTPTASIRRALCGTQPMISLALVETGLAVFKKTSMTALREKSLALTDLFIQLVEQRCANHPLGLVTPRSHSKRGSHVSFTHPHAYPIIQALIERGIIGDYREPAVLRFGFTPLYTGFVDVWNAVEALRDILDTQAYQINATRHAVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GT77</accession>
    <name>A0A2S9GT77_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cytochrome c biogenesis protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_4325</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000032">
        <property type="protein sequence ID" value="PRC90924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90924">
        <property type="protein sequence ID" value="PRC90924"/>
        <property type="gene ID" value="S2091_4325"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017004">
        <property type="term" value="P:cytochrome complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003834">
        <property type="entry name" value="Cyt_c_assmbl_TM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02683">
        <property type="entry name" value="DsbD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="74"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="126"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="160"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="202"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="domain" description="DsbD" evidence="2">
        <location>
            <begin position="13"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC90924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="242" mass="25041" checksum="3FBDF301DBA679B6" modified="2018-07-18" version="1">MSIGLASLGLAGGAGILSTLSPCVLPILPILLAGAQSSHRFGPLALTAGLATAFTAMGVLLATVGASIGLNPEHFRNTAAVVLIILSIVLLSERLQQQFARLTQGLGNAGQTWTQRIPHEGWLGQLALGLTLGLVWSPCVGPTLGAAITLASQGENPLQMTLVMLLFSLGACLPLLALSLMSRRVIQRIKGNLIGAGKIGKNALGLLLLTLGILVLGGLDKQLEAFLLTNSPEWLTTFTTSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GT86</accession>
    <name>A0A2S9GT86_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Saccharopine dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_4331</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000032">
        <property type="protein sequence ID" value="PRC90930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90930">
        <property type="protein sequence ID" value="PRC90930"/>
        <property type="gene ID" value="S2091_4331"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032095">
        <property type="entry name" value="Sacchrp_dh-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005097">
        <property type="entry name" value="Sacchrp_dh_NADP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16653">
        <property type="entry name" value="Sacchrp_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03435">
        <property type="entry name" value="Sacchrp_dh_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sacchrp_dh_NADP" evidence="1">
        <location>
            <begin position="3"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="domain" description="Sacchrp_dh_C" evidence="2">
        <location>
            <begin position="134"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC90930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="396" mass="43348" checksum="5C6F462B56D066FC" modified="2018-07-18" version="1">MKIVILGGAGLMGAGIVRDLLSERAIIDIRCVRICDSSLERMNKLKAELNDPRIDLRQLDVTNPAEIAAALDGMQLCINSVPTLAGHQMAIFEAALAARVSYIDLGGLGTYTVKQLAEHARFAAAGVTAVIGVGADPGMSNVICRAVANELDTIDSINLYWAAELVGAENPVLCPPYSVSTVLAEYAHPSTQFLDGKHVQCAPQQGREFMTLPEPWGHCEFMYSPHSEQLTVPLAEGIKEKGIREFTWKLHLPHREHEAWVGLVKAGFNDFEEPLLVDGVAIKPVDFLSALINRNIAKNAEHIPAQDSHEIHLAIGRGRKNGKACTVRCEVIVKPNPMYASYVDACTSMNASIAAQLILSTPQRAGVFAPESYFDIPSYFRELERRHFSIRLVVEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTA5</accession>
    <name>A0A2S9GTA5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NAD-dependent aldehyde dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_4332</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000032">
        <property type="protein sequence ID" value="PRC90931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90931">
        <property type="protein sequence ID" value="PRC90931"/>
        <property type="gene ID" value="S2091_4332"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016620">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldedh" evidence="2">
        <location>
            <begin position="35"/>
            <end position="487"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC90931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="516" mass="55503" checksum="944033F0BC7D6A32" modified="2018-07-18" version="1">MNLTMKQAMNSLFSIETPSYFINPRFIPAQGLVNTVRDPANGNTVGVFAESRPEEIDAVLTSATAAQRDWKQLDAKSRAKTLHALANAIETADLRYCAELMTREMGKPYPEAIGELANCAPIFRYYAELARDDAGKVAGTTQTGSFQYARYEPLGVSVHIMPFNFPILLMCWTVAASLASGNGCIIKPAPATTLCTLEFMRCFTNLPANFPNGLVNCLPGGAAVAEALIASERTHAVAFTGSVAAAKAVAAAAATLMKPAVIEAGGSDPMIISSHAPIDIAAAGATTAAFHMSGQVCTSTERIYVVDSVFDAFVAAFVNCTLKLRIGHGLQRSEIGPLVSEAARNKVMRLVDAAVAQGAVIVTGGRIPPSQERGWFYEPTILINVTHDMDIMREECFGPVASICRVADFNEAITLANDSAFGLGASIFTTSLEEAMEAAERIEAGMVWINNPLIDNDALPFGGWKLSGLGRELSRQGLDAFRRSKMVILNHKPALQDWWYPYPDSWFHDAGGRTHN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTQ2</accession>
    <name>A0A2S9GTQ2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Chloride channel protein EriC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_4200</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000029">
        <property type="protein sequence ID" value="PRC91104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91104">
        <property type="protein sequence ID" value="PRC91104"/>
        <property type="gene ID" value="S2091_4200"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005247">
        <property type="term" value="F:voltage-gated chloride channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014743">
        <property type="entry name" value="Cl-channel_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001807">
        <property type="entry name" value="Cl-channel_volt-gated"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00654">
        <property type="entry name" value="Voltage_CLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00762">
        <property type="entry name" value="CLCHANNEL"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81340">
        <property type="entry name" value="SSF81340"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="54"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="158"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="195"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="231"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="273"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="314"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="438"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="451"/>
            <end position="477"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC91104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="477" mass="50408" checksum="2B8966802176C66E" modified="2018-07-18" version="1">MIPEHSERLSARLLEIWHRGSAWIVGPVLVGLMAVGLALGSDQMSTFNMHLNKLHPYAPLLFMPLGFALLAYLGKRFVPGSQGSGIPQTIAATDAEENVNIGYLLSWRIAIGKALLTLGGIGLGASIGREGPTIQIGAAVMNSFHGRGPFQSVESRRILILAGGAAGIAAAFNTPLAGIMFAIEELSKKHVFNANSSTLVTIIGSGLISLSILGSYTYFGTTESFLDWNGSLGAILLCGIVGGAAGGLFSRLFILSTFHMPSRFAAFVKQRPILFAAVCGLIVAIIGVSCNGLIFGTGYQPTRLSLEDTASLPWYFGMAKLLATLLSSISGIAGGVFAPSLSVGAGIGDNVAALFPLMADHSAIVLLVMAAYLSGVTRAPVTSFVICMEMTNSHQMLLPLMAASVVASRISKFISPTPLYHKLAENFTEVPVQAAKQQKTRANAQTQFADRASRADEKFSSTIKKQPDIEVGRSKFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTT6</accession>
    <name>A0A2S9GTT6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cation/multidrug efflux pump</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4215</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000029">
        <property type="protein sequence ID" value="PRC91119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91119">
        <property type="protein sequence ID" value="PRC91119"/>
        <property type="gene ID" value="S2091_4215"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2090.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027463">
        <property type="entry name" value="AcrB_DN_DC_subdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001036">
        <property type="entry name" value="Acrflvin-R"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32063">
        <property type="entry name" value="PTHR32063"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00873">
        <property type="entry name" value="ACR_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00702">
        <property type="entry name" value="ACRIFLAVINRP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82714">
        <property type="entry name" value="SSF82714"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="325"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="360"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="386"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="431"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="458"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="537"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="884"/>
            <end position="906"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="913"/>
            <end position="931"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="937"/>
            <end position="958"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="988"/>
            <end position="1007"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1019"/>
            <end position="1042"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="1075" mass="115781" checksum="7EB85480501CCDBC" modified="2018-07-18" version="1">MWIVNIALRRPYTFIVMALLILLSTPLVLTKMATDIFPDINIPVISIIWNYGGLSAQEMGQRITATSERSLTTTVNDIEHIESQSLSGISVIKIFFQPNANIQTAIAQVVAIEQAQLRSLPPGITPPLIIKYSASSIPVIQLGLSSNSMTEQALSDTALNFLRPQLITVPGAAIPYPYGGKMRLVSVDLDTQAMLSKGLTSTDVVNAISAQNLTLPSGTVKMGSSEYNVTMNGSPDTIEGLNNVPVLAKNGTSTNLSEVARVRDGFSPQTNIVRQNGERGVLVSVLKNGNASTLDVVSNLRTLLPTAMQSLPKELKIKTLLDQSVFVRAAISGVIHEAVIAACLTAAMILLFLGNWRSTCIIAVSIPLSILSSLLALSAMGETINIMTLGGLALAVGILVDDATVTIENIERHLHLGSDLHTAILDGAGEIAIPALVSTLCICIVFVPMFFLTGVARYLFVPLAEAVVFAMLASYVLSRTLVPTMVMLMMKNHNQVDASAKPSLLQRVYRKFDAGFEKFRGGYVIILSKLLTHRKEFGSLFLGFCVLSLGLVFFLGRDFFPSVDSGQIRLHMRAPTGTRIEETARIADEVEKVIREIIPASELETVLDNLGLPYSGINLSYSNSGTIGTMDGEIQISLNEHHQPSVSYVDKLRSELPKRFPSVEFFFQPADIVTQILNFGLPAALDVQISGSNLANNYQLASKLMKQVKQIPGAVDVHIQQKLNLPTLAMTMDRNQIKQLGLNPVDLAQNLLVSLSGSSQTAPAFWLNPGNGVVYNIAVQTPQYQISDMDALLRTPVKSGTNTNPNTAPQLLSNLVQVAPAEQMADVSHYNITPVIDLYVSVQGRDLGGVSDQVEKLVEQMRPDLPRGTHMVIRGQVETMKSSFFGLGIGLLMAIVLVYLLIVVNFQSWVDPFIIITALPAALAGIVWMLFLTGTTLSVPALTGAIMTMGVATANSILMVSFARQRMLDGAPPLSAALEAGATRIRPVLMTALAMIIGMIPMAIGFGEGAEQNAPLGRAVIGGLLFATVSTLFFVPVVFAGIHRYLEHRKEARNHSLNLSPSLSAANAGNEEGNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTU1</accession>
    <name>A0A2S9GTU1_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Hydroxyacylglutathione hydrolase</fullName>
            <ecNumber evidence="5">3.1.2.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Glyoxalase II</fullName>
            <shortName evidence="5">Glx II</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">gloB</name>
        <name evidence="7" type="ORF">S2091_4182</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>an S-(2-hydroxyacyl)glutathione + H2O = a 2-hydroxy carboxylate + glutathione + H(+)</text>
            <dbReference type="Rhea" id="RHEA:21864"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:58896"/>
            <dbReference type="ChEBI" id="CHEBI:71261"/>
            <dbReference type="EC" id="3.1.2.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="5">Binds 2 Zn(2+) ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Secondary metabolite metabolism; methylglyoxal degradation; (R)-lactate from methylglyoxal: step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.2.6" evidence="5"/>
    <dbReference type="EMBL" id="PUGF01000029">
        <property type="protein sequence ID" value="PRC91086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91086">
        <property type="protein sequence ID" value="PRC91086"/>
        <property type="gene ID" value="S2091_4182"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00619">
        <property type="reaction ID" value="UER00676"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004416">
        <property type="term" value="F:hydroxyacylglutathione hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019243">
        <property type="term" value="P:methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07723">
        <property type="entry name" value="hydroxyacylglutathione_hydrolase_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01374">
        <property type="entry name" value="Glyoxalase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035680">
        <property type="entry name" value="Clx_II_MBL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032282">
        <property type="entry name" value="HAGH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017782">
        <property type="entry name" value="Hydroxyacylglutathione_Hdrlase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16123">
        <property type="entry name" value="HAGH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005457">
        <property type="entry name" value="Glx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03413">
        <property type="entry name" value="GSH_gloB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Lactamase_B" evidence="6">
        <location>
            <begin position="14"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="55"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="57"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="59"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="60"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="117"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="136"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="174"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC91086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="263" mass="28914" checksum="841328F626942CC4" modified="2018-07-18" version="1">MTNIHIQQIPAFDDNYFWLIHNDQNAIIVDPGDAAPVLAYLNQHQLTLSAILITHHHADHIGGVDELLSHAAVPVYGPLADQQSGRISTITQGCQQGETLFLKELNLHFDVLEVPGHTSTHIAYYCAALSSLFCGDTLFAGGCGRLFEGTPAQMVASLRKISALPANTNVYCAHEYTLSNLRFALAVEPNNAALQNRFKLANVARENGLSTVPSQLNLELQTNPFLRSSSPEIIHTLQNKQKLSDVTDEVTVFAAVREWKNTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GU56</accession>
    <name>A0A2S9GU56_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Efflux pump membrane transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_4047</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 4">Cell inner membrane</location>
            <topology evidence="2 4">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000026">
        <property type="protein sequence ID" value="PRC91262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91262">
        <property type="protein sequence ID" value="PRC91262"/>
        <property type="gene ID" value="S2091_4047"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015562">
        <property type="term" value="F:efflux transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042908">
        <property type="term" value="P:xenobiotic transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2090.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027463">
        <property type="entry name" value="AcrB_DN_DC_subdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001036">
        <property type="entry name" value="Acrflvin-R"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004764">
        <property type="entry name" value="HAE1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32063">
        <property type="entry name" value="PTHR32063"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00873">
        <property type="entry name" value="ACR_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00702">
        <property type="entry name" value="ACRIFLAVINRP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82714">
        <property type="entry name" value="SSF82714"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00915">
        <property type="entry name" value="2A0602"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="341"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="368"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="394"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="436"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="472"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="536"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="866"/>
            <end position="887"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="894"/>
            <end position="916"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="922"/>
            <end position="947"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="968"/>
            <end position="991"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="1003"/>
            <end position="1025"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU364070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC91262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="1047" mass="113051" checksum="5789BE5D2039E91A" modified="2018-07-18" version="1">MFSRFFIHRPIFASVIAIIITLAGLAAMRVLPIEQYPQIVPAVVSVSAIYPGATPETIAQSVASPLEQQVNGVENMLYMQSSSSSTGQLNLSVYFAVGTDPDQATIDVNNRVQAAMKTMPEEVQRQGITVRKKSTSVLSVISLNSPSDQYDRNYLSNYALLNVLDELKRIPGMGDVNIMGGTEYAMRLWLRPDRMAQLSLTPSDIVTAVREQNAQFAAGKIGAQPSDAAINFTYTVSAKGRLSTVEEFENIIVRSMPDGSKIRVQDVARVEMGGNDYDVVAMRNGKPAVGIVTYLQPNANALEVSSAVANKMAELKKRFPSGLDYAIPFDTTDFVKVSVEAVVHTLLEAIVLVFVVVYLFLQNFRATLIPCIAVPVSLIGTFAGMLMLGFSINLLTLFGMVLAIGIVVDDAIVVLENVERIMSEKKCSAKEASIQAMQEVSGPVIAIVLVLCAVFLPVAFMGGMTGVMYKQFAVTIAISVIISGIVALTLTPAMCALMLKPGHQKPARFFIWFNTFFDKLTNNYVGGARFLQRRSGLALGMVAALLLVTGLLYSKVPGSLVPAEDMGKLTASISLPDASSLTRTISAANEYDQQLLADPNIDSVTTFTGFDILSGSKLSNRATSFISLKDWSQRQGEGQDSFSLASHYIALGRTIQSGIVNVFNSAPIMGMSATGGLESFLQDRNDQGSQKLSEATQKLLDAAKKRPEFSNVTSTFRANVPQKYLDLDREKAKALGVNINEVFATMQATFGQLYVNDFNKFGRTYKVQVQSEADFRARPEDIANIYVRSEQGIMIPLASLVTVQSSFGPELVDRFNIFNAAKIMAQPAPGVSSGQAIAALEEVVQQALGSDYSLAWSGSAYQEKQAGGTAVVAFGFGILMVFLILAAQYERWSLPLAVITAVPFALFGALLAAYVFKMSNDVYFQIGMVTLIGLAAKNAILIVEFAIMKHEEGMTLLDASLEAARLRFRPIIMTSLAFILGCVPLVTSSGAGAASRHSLGTPVIGGMLAATFIAIFFIPLFFRLIMQASGRGKAKVQTLETGAQDHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUF5</accession>
    <name>A0A2S9GUF5_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ribosomal protein L11 methyltransferase</fullName>
            <shortName evidence="2">L11 Mtase</shortName>
            <ecNumber evidence="2">2.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">prmA</name>
        <name evidence="3" type="ORF">S2091_3910</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Methylates ribosomal protein L11.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>L-lysyl-[protein] + 3 S-adenosyl-L-methionine = 3 H(+) + N(6),N(6),N(6)-trimethyl-L-lysyl-[protein] + 3 S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:54192"/>
            <dbReference type="Rhea" id="RHEA-COMP:9752"/>
            <dbReference type="Rhea" id="RHEA-COMP:13826"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:61961"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the methyltransferase superfamily. PrmA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="2"/>
    <dbReference type="EMBL" id="PUGF01000024">
        <property type="protein sequence ID" value="PRC91365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91365">
        <property type="protein sequence ID" value="PRC91365"/>
        <property type="gene ID" value="S2091_3910"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008276">
        <property type="term" value="F:protein methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00735">
        <property type="entry name" value="Methyltr_PrmA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004498">
        <property type="entry name" value="Ribosomal_PrmA_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000401">
        <property type="entry name" value="RPL11_MTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00406">
        <property type="entry name" value="prmA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="2" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 3" id="KW-0808">Transferase</keyword>
    <feature type="binding site" evidence="2">
        <location>
            <position position="151"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="172"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="194"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="233"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00735"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="297" mass="31986" checksum="E4075FEF252ECC10" modified="2018-07-18" version="1">MSWIEIVVEVARAQAENFSDALMELGALSVSVEDADEGTDAEQPLFGEPGMEPKEAAWERSRVIALTPTDFNHAELVELAAAHCKMPVPEHSLRSVADQDWVRLTQSQFEPMLIGKGIWVVPSWHSAPDPTAIVLELDPGLAFGTGSHPTTRLCMEWLEENPPLDKTVLDYGCGSGILAIVAKKLGAGQVEGIDIDPQAVVSAEFNAVRNHCEIDFSLPNKVTTSTYDVVVANILSNPLKLMAPMLSAKVAAGGALVLSGVLARQADEVTAAYAPFIALSVWQERDGWVALHGRRPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUF8</accession>
    <name>A0A2S9GUF8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3917</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000024">
        <property type="protein sequence ID" value="PRC91372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91372">
        <property type="protein sequence ID" value="PRC91372"/>
        <property type="gene ID" value="S2091_3917"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="410" mass="46640" checksum="8867451178AD7FFD" modified="2018-07-18" version="1">MLNNYLLNNDEHKGEHKMKKIASLLTLMLPLLLLFSAFAQAIDLDGSGSFTATGFYNLTGAEVVNGSAQGSSTPWMYQQWHCPCSIQNWEYAGVYEKSKGFRLDQESLFGLQLRKEFTPTLSVTGQFVMRAQNPNNGSSPSVDWLYASWSPAPDSPFTFQVGRLRIPLYYYSDYLYIGYSYPWVRPPPDVYGWPIYEYDGGNASYHIQLGKSAWTMNASVWTGNFKQTYDAYDTLIYDTNPTTESWKKMWGSYVSMTNGTFDVRAMAMEYRDTTTINNPGAPATTVVSNQFTRIEGLSANMDYQNWVVRGEIDRYQQQSTALGINNVYKYNLLGVGYKVGDFTPMLTHSQYTTVAQPIEAQKTNSIVVRWDFRPNTALKVQYDVNIDESQYPYKFFGNSHLLSVSLQGIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUS9</accession>
    <name>A0A2S9GUS9_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Flagellin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_3765</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Secreted</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Bacterial flagellum</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the bacterial flagellin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000022">
        <property type="protein sequence ID" value="PRC91487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91487">
        <property type="protein sequence ID" value="PRC91487"/>
        <property type="gene ID" value="S2091_3765"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009288">
        <property type="term" value="C:bacterial-type flagellum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001492">
        <property type="entry name" value="Flagellin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046358">
        <property type="entry name" value="Flagellin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042187">
        <property type="entry name" value="Flagellin_C_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010810">
        <property type="entry name" value="Flagellin_hook_IN_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001029">
        <property type="entry name" value="Flagellin_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42792">
        <property type="entry name" value="PTHR42792"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00700">
        <property type="entry name" value="Flagellin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07196">
        <property type="entry name" value="Flagellin_IN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00669">
        <property type="entry name" value="Flagellin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00207">
        <property type="entry name" value="FLAGELLIN"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0975">Bacterial flagellum</keyword>
    <keyword evidence="6" id="KW-0966">Cell projection</keyword>
    <keyword evidence="6" id="KW-0969">Cilium</keyword>
    <keyword evidence="6" id="KW-0282">Flagellum</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <feature type="domain" description="Flagellin_N" evidence="4">
        <location>
            <begin position="5"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="domain" description="Flagellin_C" evidence="5">
        <location>
            <begin position="423"/>
            <end position="508"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU362073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC91487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="509" mass="50328" checksum="72BA552B8C405C4B" modified="2018-07-18" version="1">MLDAINTNIIALQTEDNLNKSQMSLSTSIQRLSSGLRINSATDDPAGLAIASRMSSQLSGLDQAAQNASTGISMLQTADGGLATTNSLLQSMRSLAVEAANGTNSTTDLASLQVQITQLQAELQQVSTTTQYNGINLIDGSLSNLQFQVGANAGQTISFGIGNAQQTALGNNVVSLTGGAGVAAGDAITEAGVVSSSVSAVNNVQLQTLTVQGNGTTQTISVAISSSAQSIATSINNLTSSTGITANATTTATLAFVTAGTQTFNIDGVGINASYSVSSGYSAAVNAINLQTGNTGVTASLTAAGITLSNTNGADIAVTNTGTNNLTLAGTVNTGTQAAPVFTAGAAVTLSSAASTTTTAVVGGNITFASQGGFAITTSVGTAATGGLFSVVTANGSTLNTVGSINLTTVSGNGTPTGANSALDIIDAAIAQINTSRASLGSLENRFTAAGSNLQTASLNLSSSLSTEQDTNFAAETTNLSRGQILQQAGTAMLAQANSLPNGVLALLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUT6</accession>
    <name>A0A2S9GUT6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ThrC: threonine synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_3752</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 4">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the threonine synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000022">
        <property type="protein sequence ID" value="PRC91474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91474">
        <property type="protein sequence ID" value="PRC91474"/>
        <property type="gene ID" value="S2091_3752"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1380.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="PLP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029144">
        <property type="entry name" value="Thr_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037158">
        <property type="entry name" value="Thr_synth_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004450">
        <property type="entry name" value="Thr_synthase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="Trypto_synt_PLP_dependent"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14821">
        <property type="entry name" value="Thr_synth_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="SSF53686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00260">
        <property type="entry name" value="thrC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thr_synth_N" evidence="6">
        <location>
            <begin position="2"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="domain" description="PALP" evidence="5">
        <location>
            <begin position="95"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="4">
        <location>
            <position position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR604450-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF14821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC91474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="480" mass="52496" checksum="6706CF42CC0AF45B" modified="2018-07-18" version="1">MHYVSTRGIAAQDTFSTILLGGLAEDGGLYLPEHYPQISDAELNQWRTFSYAELACAVLAKFAPDIPLADLRALTQKTYTAATYCNTSGDASKITPLQELEPGLYLQALSNGPTLAFKDMAMQLLGNLFEYTLDKQHAELNIFGATSGDTGSAAEYAMRGKRGIRVFMLSPHKKMSAFQTAQMFSLTDENIFNIAVEGVFDDCQDLVKAVSNDLAFKNRQKIGTVNSINWARVVAQVVYYFRGYLSATTNNSQQVSFTVPSGNFGNVCAGHIARMMGLPIAKLVVATNENDVLDEFFKTGKYQVRKSEQTYHTSSPSMDISKASNFERFVFDLIGRDSARLLALFSKVEKTGGFDLSGAPGSDGDEFKRIAEFGFSSGKSVHTDRLATIRSVREKYGITVDTHTADGIKVALEQRDNNVAMIVLETALPAKFNETIREALGVDAPRPAGFENIESLPQHFVVMVADAAQMKAYIAGKTGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUZ8</accession>
    <name>A0A2S9GUZ8_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">Cobyric acid synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">cobQ</name>
        <name evidence="11" type="ORF">S2091_3812</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 7">Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 7">Cofactor biosynthesis; adenosylcobalamin biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the CobB/CobQ family. CobQ subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000022">
        <property type="protein sequence ID" value="PRC91534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91534">
        <property type="protein sequence ID" value="PRC91534"/>
        <property type="gene ID" value="S2091_3812"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00148"/>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015420">
        <property type="term" value="F:ABC-type vitamin B12 transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009236">
        <property type="term" value="P:cobalamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01750">
        <property type="entry name" value="GATase1_CobQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.109.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00028">
        <property type="entry name" value="CobQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012825">
        <property type="entry name" value="BluB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002586">
        <property type="entry name" value="CobQ/CobB/MinD/ParA_Nub-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033949">
        <property type="entry name" value="CobQ_GATase1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004459">
        <property type="entry name" value="CobQ_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011698">
        <property type="entry name" value="GATase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029479">
        <property type="entry name" value="Nitroreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000415">
        <property type="entry name" value="Nitroreductase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21343:SF1">
        <property type="entry name" value="PTHR21343:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01656">
        <property type="entry name" value="CbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07685">
        <property type="entry name" value="GATase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00881">
        <property type="entry name" value="Nitroreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55469">
        <property type="entry name" value="SSF55469"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02476">
        <property type="entry name" value="BluB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00313">
        <property type="entry name" value="cobQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0169">Cobalamin biosynthesis</keyword>
    <keyword evidence="5 7" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CbiA" evidence="9">
        <location>
            <begin position="8"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="domain" description="GATase_3" evidence="10">
        <location>
            <begin position="252"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="domain" description="Nitroreductase" evidence="8">
        <location>
            <begin position="506"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="7">
        <location>
            <position position="331"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="428"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00025166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF07685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC91534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="706" mass="77280" checksum="986AE1D7F96330EA" modified="2018-07-18" version="1">MTSPFKTLMVQGTTSDAGKTTVVAALCRLLARQGIKVVPFKPQNMALNSAVTEDGGEIGRAQALQAQAAGIAPHSDMNPVLLKPSSDTGAQIIIHGKVKTEMNAQDYHQYKTVAMQAVLESYQRLGERFDCIVVEGAGSPAEINLRDRDIANMGFAEAVDCPVILVADIDRGGVFAHIVGTLSCLSESEQRRIVGFVINRFRGDIKLLEPGLDWLEKQTGKPVLAVLPYLHGLFLDAEDAIQANQVTTGEFRIVVPVFPRISNHTDFDALRAHPNVDLKFIGPGQAIPPADLIILPGSKNTRADLEWLHQQGWDVALHKHLRYGGKVIGICGGFQMLGNSVSDNLGIEGIAGVSPGLNLLDMVTEIGREKRLGNVAGQCAFAAAQVSGYEIHMGTSAGTALDAPAFYIDGRPEGAISQDNQILGTYLHGLFDHPEACSALLRWAGLDSETVVDLSALRNHSLDRIADATQPLFDALVAMNNQPVLQKTPDSEQFSAPEIAGVYRAIRERRDMRHFHSQPIEAEQLLRFIQAAHQGPSVGYMQPWRFIRITDIELRKQIHQHVNDERLLTAQALGERTNEFMRLKVEGILACAELLVVGLADKREDYVFGRRTMPEMDLASASCAIQNFWLAARAEGIGVGWVSMFDPAQIRTLCAMPEGSQPIALLCVGHVEKFYPAPMLEVEGWDTRRLLSDIVFENAWESSKLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GV18</accession>
    <name>A0A2S9GV18_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Sulfurtransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_3664</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000021">
        <property type="protein sequence ID" value="PRC91548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91548">
        <property type="protein sequence ID" value="PRC91548"/>
        <property type="gene ID" value="S2091_3664"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004792">
        <property type="term" value="F:thiosulfate sulfurtransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001307">
        <property type="entry name" value="Thiosulphate_STrfase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045078">
        <property type="entry name" value="TST/MPST-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11364">
        <property type="entry name" value="PTHR11364"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="SSF52821"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00683">
        <property type="entry name" value="RHODANESE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Rhodanese" evidence="3">
        <location>
            <begin position="22"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodanese" evidence="3">
        <location>
            <begin position="175"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC91548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="290" mass="31396" checksum="1D3E02F47A7DE979" modified="2018-07-18" version="1">MGSNLATFTTLISVNELAQHSKQPNWIILDCRNDLANPDAGPAAFAQGHIPTAQFVHLDQDLSDHKRNANGVFFGRHPLPERAAFIAKLRAWGISNDTQVLAYDAHGGMYAARLWWMLRWVGHAAVAVLDGGLPAWVEANQPLDTQIFEAAPGAISEQTALVSLVSVNDVVVNIETRHKTVVDARSPDRYRGENETIDPVGGHIPGAKNRFFKDNLQVNGRFKSAQELRAELGAVIKEPHNAIMQCGSGVTACHNLLALEIAGMPGAALYAGSWSEWCSDPARPIALGTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GV58</accession>
    <name>A0A2S9GV58_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Valine--tRNA ligase</fullName>
            <ecNumber evidence="8">6.1.1.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Valyl-tRNA synthetase</fullName>
            <shortName evidence="8">ValRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">valS</name>
        <name evidence="13" type="ORF">S2091_3706</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>ATP + L-valine + tRNA(Val) = AMP + diphosphate + L-valyl-tRNA(Val)</text>
            <dbReference type="Rhea" id="RHEA:10704"/>
            <dbReference type="Rhea" id="RHEA-COMP:9672"/>
            <dbReference type="Rhea" id="RHEA-COMP:9708"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57762"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78537"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.9"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="8">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="8">The C-terminal coiled-coil domain is crucial for aminoacylation activity.</text>
    </comment>
    <comment type="domain">
        <text evidence="8">ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.9" evidence="8"/>
    <dbReference type="EMBL" id="PUGF01000021">
        <property type="protein sequence ID" value="PRC91590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91590">
        <property type="protein sequence ID" value="PRC91590"/>
        <property type="gene ID" value="S2091_3706"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA editing activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004832">
        <property type="term" value="F:valine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006438">
        <property type="term" value="P:valyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07962">
        <property type="entry name" value="Anticodon_Ia_Val"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.740.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02004">
        <property type="entry name" value="Val_tRNA_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002300">
        <property type="entry name" value="aa-tRNA-synth_Ia"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033705">
        <property type="entry name" value="Anticodon_Ia_Val"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013155">
        <property type="entry name" value="M/V/L/I-tRNA-synth_anticd-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010978">
        <property type="entry name" value="tRNA-bd_arm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037118">
        <property type="entry name" value="Val-tRNA_synth_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019499">
        <property type="entry name" value="Val-tRNA_synth_tRNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009008">
        <property type="entry name" value="Val/Leu/Ile-tRNA-synth_edit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002303">
        <property type="entry name" value="Valyl-tRNA_ligase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11946">
        <property type="entry name" value="PTHR11946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08264">
        <property type="entry name" value="Anticodon_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00133">
        <property type="entry name" value="tRNA-synt_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10458">
        <property type="entry name" value="Val_tRNA-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00986">
        <property type="entry name" value="TRNASYNTHVAL"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46589">
        <property type="entry name" value="SSF46589"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="SSF47323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50677">
        <property type="entry name" value="SSF50677"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00422">
        <property type="entry name" value="valS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 8 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2 8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 8 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 8 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 8 9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="tRNA-synt_1" evidence="10">
        <location>
            <begin position="18"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="domain" description="Anticodon_1" evidence="11">
        <location>
            <begin position="667"/>
            <end position="819"/>
        </location>
    </feature>
    <feature type="domain" description="Val_tRNA-synt_C" evidence="12">
        <location>
            <begin position="878"/>
            <end position="942"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="883"/>
            <end position="938"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'HIGH' region" evidence="8">
        <location>
            <begin position="44"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'KMSKS' region" evidence="8">
        <location>
            <begin position="539"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="542"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF08264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF10458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PRC91590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="945" mass="106122" checksum="51CD4E17D09654C0" modified="2018-07-18" version="1">MELAKSFEPAEIEKIWRNEWEQRGYFAASMDPNAPSFCIQLPPPNVTGTLHMGHAFNQTIMDGLTRYYRMRGHNTSWVPGTDHAGIATQIVVERQLDAQKISRHDLGREKFVEKVWEWKEQSGSTITGQMRRMGASADWAREYFTMDAPRSKVVADVFVRLFEQGLIYRGKRLVNWDPVLGTAVSDLEVVSEEEDGSMWYIHYPFADGSGQVTVATTRPETLLGDVAVAVDPTDERFTHLVGKMLKLPLTDREIPIIADEYVDKAFGTGCVKITPAHDFNDYAVGQRHHLPLISILTLDAKIVDEAPEAYRGLDRFVARKKMVADLDAQGLLESVKPHKLMVPRGDRTNVVIEPMLTDQWFMAMSKPAPEGTHFPGKSIAEVALEKVANGEVKFVPENWSTTYNQWLGNIQDWCISRQLWWGHQIPAWYGDDGQIFVAHSEAEAKSKAAQAGYNGALKRDEDVLDTWFSSALVPFSTMGWPEQTPDLAAFLPSSVLVTGFDIIFFWVARMVMMTAHFTGKVPFHTVYVHGLVRDSSGQKMSKSKGNTLDPIDLIDGISVDALVGKRTTGLMNPKDAEKISKATRKEFADGIQAYGTDALRFTMASYASLGRNINFDLGRCEGYRNFCNKLWNATRFVLMNTEGKDCGFDSHVDGVCKPEYLDFSPADRWIVSALQRTEQDIAKGFADYRFDNIAASIYQFVWDEYCDWYLEVAKVQMQHGSEAQQRATRRTLLRVLETILRLAHPIIPFITESLWQTVAPLTGHKMNPAGDSIMLQAYPEANLDKLDEAAEGWMTALKTLTDSCRNLRGEMQLSPAQRVPLLMQAVSSEEKLRLQAFAPYLQALAKLSEVQVLDALPESPAPVSIVGETKLMLKVEIDVAAERERLNKEITRLDTEITKAQAKLDNEGFVARAPAQVVAQEKERVANFSATLNKLREQFAKLPVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVB3</accession>
    <name>A0A2S9GVB3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="10">4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">S2091_3591</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000020">
        <property type="protein sequence ID" value="PRC91653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91653">
        <property type="protein sequence ID" value="PRC91653"/>
        <property type="gene ID" value="S2091_3591"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038731">
        <property type="entry name" value="RgtA/B/C-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13231">
        <property type="entry name" value="PMT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="25"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="101"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="133"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="155"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="185"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="225"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="251"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="287"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="318"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="343"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="372"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="410"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="437"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="domain" description="PMT_2" evidence="9">
        <location>
            <begin position="81"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF13231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC91653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="570" mass="64737" checksum="8A7BBCB790A64867" modified="2018-07-18" version="1">MRQKQTTMQNAGLRITQRGMQNPDWLIWLLAFICVWAGLGAYGVLNNNEGLYAQIPREMLNSGDIKYWIIPHLNGLPYMEKPPLLYWLTALAFTLFGQADWVVRLVPSLSGLACVGLMLNFGQRIYRPQVGRLAALMFISGLGVMIISRTLLFDMLLTAFLTAALLFAYLYKLEGHKRDLRIAHVSLAFAVLTKGFVALLLFGSVTLVWIILVHGSSAWKQFSKWFDLVSICLFFAITVPWFVAASLIEPIFLWFFFVNEHVLRFLGLRIPHDFYSGSWWYYLPRMVIYLFPWSLLLPIALLSTWTRLSRVEIQEFTILRKTLVFGWLVPLLFFSISSAKANYYVIVSMPFAALNLALLLEQSDFLKGKRSTILGVVVALLTGAAAITLQAAPNLVSSELVILGLPWHDYAVIALWSATGLSLLAALLAWRVPNVGLVSYIVLPLFSMGILLVTANAMDESISDRSMAAFIQQTVPNRTVYLYRNFEQNSSLPFYLKKPLNVIDSVSSDLYWGNQLRPENTIMLSREQFKLLKEPVVVIVPNAYLDEFAHKKMHTKFIKNKQFSHATVFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVV2</accession>
    <name>A0A2S9GVV2_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Flagellar biosynthesis protein FlhF</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Flagella-associated GTP-binding protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">S2091_3408</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the GTP-binding SRP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000018">
        <property type="protein sequence ID" value="PRC91852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91852">
        <property type="protein sequence ID" value="PRC91852"/>
        <property type="gene ID" value="S2091_3408"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044781">
        <property type="term" value="P:bacterial-type flagellum organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006614">
        <property type="term" value="P:SRP-dependent cotranslational protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020006">
        <property type="entry name" value="FlhF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000897">
        <property type="entry name" value="SRP54_GTPase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43134:SF3">
        <property type="entry name" value="PTHR43134:SF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00448">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00962">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03499">
        <property type="entry name" value="FlhF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1005">Bacterial flagellum biogenesis</keyword>
    <keyword evidence="7" id="KW-1006">Bacterial flagellum protein export</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="13" id="KW-0966">Cell projection</keyword>
    <keyword evidence="13" id="KW-0969">Cilium</keyword>
    <keyword evidence="13" id="KW-0282">Flagellum</keyword>
    <keyword evidence="6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="domain" description="AAA" evidence="11">
        <location>
            <begin position="211"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="domain" description="SRP54" evidence="12">
        <location>
            <begin position="212"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="84"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00014919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00025337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00030866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PRC91852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="439" mass="48414" checksum="3037D337FC23AD4D" modified="2018-07-18" version="1">MNVKRFSAATSREALHKLRDAMGPDAVIISNRNVNGQVEILALDEGEMADLHETANEFEFIPPRKQEAATNPIIQSQTKFAIKKKQNEQSLQMRDNPIEVTQPSSLSNSLPSANAPDMSGALELMSELRSMRGMMETQLAEINWGNTQRKEPHKAQLLREMLSTGFSASLSRYLIENMPKTSDLKQGLIWIKAILSKNLNTISCDSDMLEQGGVFALVGPTGVGKTTTTAKLAARCVMRHGASKLALITTDGYRIGGYEQLRIYGKILGVMVHAVKDEADLRIALSELKNKHTVLIDTVGMSQRDRLVAEQVAMLSGANVNKLLCLNATSTGETLTEVIRSYQGAGLYGCIITKMDEAANIGAVLDAIIRQKLTMFYLANGQRVPEDLHIANKHYLVEHAFKLKREQAAFQFQDDELPMLMATASAAMHDRQLREVSLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVW2</accession>
    <name>A0A2S9GVW2_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Cytokinin riboside 5'-monophosphate phosphoribohydrolase</fullName>
            <ecNumber evidence="2">3.2.2.n1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3418</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>AMP + H2O = adenine + D-ribose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:20129"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16708"/>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="3.2.2.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the LOG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.2.n1" evidence="2"/>
    <dbReference type="EMBL" id="PUGF01000018">
        <property type="protein sequence ID" value="PRC91862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91862">
        <property type="protein sequence ID" value="PRC91862"/>
        <property type="gene ID" value="S2091_3418"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008714">
        <property type="term" value="F:AMP nucleosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009691">
        <property type="term" value="P:cytokinin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005269">
        <property type="entry name" value="LOG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031100">
        <property type="entry name" value="LOG_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03641">
        <property type="entry name" value="Lysine_decarbox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00730">
        <property type="entry name" value="TIGR00730"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0203">Cytokinin biosynthesis</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU363015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="181" mass="19523" checksum="71BDD67FBDA8F754" modified="2018-07-18" version="1">MKSICVYCGSATGISPSYADAARSLAGVLVGHNLNLIYGGGNIGLMGIIADEVMRLGGEVTGVIPKALVDKEVAHMALTRLYIVNDMHERKAMMASLCDGFIALPGGIGTLEELFEMLTWLQLEFHQKPVGLLNVGGFYDGLISFLDHTVLQGFLKPTHHALLLKSSDAEDLILQLKAHFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GW53</accession>
    <name>A0A2S9GW53_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3282</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000017">
        <property type="protein sequence ID" value="PRC91940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91940">
        <property type="protein sequence ID" value="PRC91940"/>
        <property type="gene ID" value="S2091_3282"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="332"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="332"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="367"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="404"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="428"/>
            <end position="459"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="459" mass="48653" checksum="7617191D20F5B1F9" modified="2018-07-18" version="1">MKKIAITLAILLAGCSAKEQSDTATQPAVNQSDSQSSTQAMPDTTQVSAQQSGVSSQEYAPPAPQSVVSVYVEPPLVQPSPIRVDWAPPPMLVDTPPPQPSDDEIWTGGYWVWEGNWVWAHGSWAPPPRPGYHWNNPYYDHRDNSVIFVNGFWAAPGISFVAPSLNANIAIGVITLGVIAGSRPNGPEGVFIPAPPGSYYGLIVPAPIGTSPAVVSGLPPIIRSGMHITNNNQTNTTNITNVTVIAPANSTANGQAVNTSIPAQPHLAAAQTPVVNAAAPEPVSTKAIPTYVAGHPPMTLPSAQVVRPIVPSALIHPHTNVAPAAEITSARQVSTVSAHSQPVVPNSKHTKPNNQIEHPSPIAPPTTRPTTSESEHNNQNHVRPNETPPTQVRSPVVETKPSPVKRAEPPPTNEVSPIPPQPVEPSKAEPQKVDENLHKKLAPKNSKEEGKPADKKEHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GW63</accession>
    <name>A0A2S9GW63_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_3296</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="PUGF01000017">
        <property type="protein sequence ID" value="PRC91954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91954">
        <property type="protein sequence ID" value="PRC91954"/>
        <property type="gene ID" value="S2091_3296"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004673">
        <property type="term" value="F:protein histidine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011495">
        <property type="entry name" value="Sig_transdc_His_kin_sub2_dim/P"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07568">
        <property type="entry name" value="HisKA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="161"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="8">
        <location>
            <begin position="186"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="7">
        <location>
            <begin position="281"/>
            <end position="475"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC91954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="483" mass="53662" checksum="9F148A9A002198C6" modified="2018-07-18" version="1">MRISPTLKLSAVISIASVTLLAATIIILQVMDTRHTEATLNLNAAVRKISLIRGFLPELSSPSYQRAARQWQAQFSELTPILMSIPPLDKQTQSLRARILENHAAVGALFGMLSNAKQDLARKEDLQIIQEQLDVRTSSMVSDILAMNDVAAAYINTQKEWMHGLLAVSVTLLAGVILGLLHIFQRRIVAPIIKLEEATERFSKGTFDQAITISGSDEITALAASFDYMRITLRDRLAELDTSNANIRTEITERKLAAELLEQSFVRIQSALQEKDLLLGEIHHRVKNNLQVVQSLLNLQSSQINDATVKSMLMDSQNRIQSMALIHQTLYQSHDFASVDFGEFLNALVPTLVSSYCVDVRNVELKIDAGSVFLPINSAIPCGLLINELITNALKHAFPDNRQGEIAVSLTRHDKNKILLVISDTGVGIPSELDVDNVETLGLRLVALLSQQLEGTLTINRRDPTRFSLEWESQESDNKSDLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWB2</accession>
    <name>A0A2S9GWB2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ABC-type multidrug transport system ATPase component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_3346</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000017">
        <property type="protein sequence ID" value="PRC92004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92004">
        <property type="protein sequence ID" value="PRC92004"/>
        <property type="gene ID" value="S2091_3346"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-1278">Translocase</keyword>
    <feature type="domain" description="ABC transporter" evidence="7">
        <location>
            <begin position="5"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="37"/>
            <end position="44"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC92004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="285" mass="31471" checksum="CFDBF1D5AF18EA59" modified="2018-07-18" version="1">MTPIISAKGVSKRYGNQVAVDNISFDIPSGRIVGLIGPNGSGKTTTLKALLGLIPFDGALSVLGLDPRTQRDELMKQVCFIADVAILPSWLRVSDAIDFVAGIHPQFNRAKAESYIAHTKLQPSMKVKAMSKGMVVQLHLALVMAIDVKLLVLDEPTLGLDILYRKQFYQNLLEDYFDEQKTIIITTHQVEEVEHILSDLMFIRDGKIILSATMDEVSQRYVEVMIEPERLSAAKELGPIDQRTVFGKSVMLFDGVAHEQLAALGETRIPNIADLFVATMKGSYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWN6</accession>
    <name>A0A2S9GWN6_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Acetyltransferase component of pyruvate dehydrogenase complex</fullName>
            <ecNumber evidence="7">2.3.1.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">S2091_3255</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>(R)-N(6)-dihydrolipoyl-L-lysyl-[protein] + acetyl-CoA = (R)-N(6)-(S(8)-acetyldihydrolipoyl)-L-lysyl-[protein] + CoA</text>
            <dbReference type="Rhea" id="RHEA:17017"/>
            <dbReference type="Rhea" id="RHEA-COMP:10475"/>
            <dbReference type="Rhea" id="RHEA-COMP:10478"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:83100"/>
            <dbReference type="ChEBI" id="CHEBI:83111"/>
            <dbReference type="EC" id="2.3.1.12"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>(R)-lipoate</name>
            <dbReference type="ChEBI" id="CHEBI:83088"/>
        </cofactor>
        <text evidence="7">Binds 1 lipoyl cofactor covalently.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 7">Forms a 24-polypeptide structural core with octahedral symmetry.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the 2-oxoacid dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.12" evidence="7"/>
    <dbReference type="EMBL" id="PUGF01000016">
        <property type="protein sequence ID" value="PRC92120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92120">
        <property type="protein sequence ID" value="PRC92120"/>
        <property type="gene ID" value="S2091_3255"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045254">
        <property type="term" value="C:pyruvate dehydrogenase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004742">
        <property type="term" value="F:dihydrolipoyllysine-residue acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.320.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003016">
        <property type="entry name" value="2-oxoA_DH_lipoyl-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001078">
        <property type="entry name" value="2-oxoacid_DH_actylTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006256">
        <property type="entry name" value="AcTrfase_Pyrv_DH_cplx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036625">
        <property type="entry name" value="E3-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004167">
        <property type="entry name" value="PSBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43178:SF2">
        <property type="entry name" value="PTHR43178:SF2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00198">
        <property type="entry name" value="2-oxoacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02817">
        <property type="entry name" value="E3_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47005">
        <property type="entry name" value="SSF47005"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="SSF51230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01348">
        <property type="entry name" value="PDHac_trf_long"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00189">
        <property type="entry name" value="LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51826">
        <property type="entry name" value="PSBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5 7" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="4 7" id="KW-0450">Lipoyl</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="9">
        <location>
            <begin position="3"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="domain" description="Peripheral subunit-binding (PSBD)" evidence="10">
        <location>
            <begin position="133"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="107"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00025211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC92120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="435" mass="45667" checksum="1C608A2F2983528D" modified="2018-07-18" version="1">MSTIEIKVPDIGDFKEVEIIELMVKVGDTIKVDQSLLTVESDKASMEIPSSHAGVVKEIKVKMGDKVAKDSLVLMLEVSETAAVPAATPVPTSSPAAVAAPAPVAAQAPAPAPAPTPAPIAEAAPQSSGNKAHASPSIRKFARELGVDLSRVAGTGPKSRILTSDVQNFVKGVMQAPVAASAPAAGSGTGMNLLPWPSLDFSKFGATETVALSRIKKLSGPNLHRNWVMIPHVTQFDEADITDLEEFRKSSNTAMAKSGVKLTMLAFVIKASVAALKKFSAFNSSLDAKGENLILKQYYNIGFAADTPNGLMVPVIKNADQKSLSQIAVEMGELSAQARDGKLKPADMQGATFTISSLGGIGGTAFTPIINAPEVAILGLSKSSIKPVWDGAKFEPRLMLPLSLSYDHRVIDGAMAARFTAYLAEVVADLRKTLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWR1</accession>
    <name>A0A2S9GWR1_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Isoprenyl transferase</fullName>
            <ecNumber evidence="2">2.5.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3066</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="2">Binds 2 magnesium ions per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPP synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.-" evidence="2"/>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92150">
        <property type="protein sequence ID" value="PRC92150"/>
        <property type="gene ID" value="S2091_3066"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004659">
        <property type="term" value="F:prenyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00475">
        <property type="entry name" value="Cis_IPPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01139">
        <property type="entry name" value="ISPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001441">
        <property type="entry name" value="UPP_synth-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018520">
        <property type="entry name" value="UPP_synth-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036424">
        <property type="entry name" value="UPP_synth-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10291">
        <property type="entry name" value="PTHR10291"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01255">
        <property type="entry name" value="Prenyltransf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64005">
        <property type="entry name" value="SSF64005"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00055">
        <property type="entry name" value="uppS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01066">
        <property type="entry name" value="UPP_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2 3" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="26"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="70"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="195"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="25"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="73"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="25"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="30"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="38"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="42"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="74"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="76"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="189"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="208"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="252" mass="28827" checksum="61CCBF6C3AB09CE3" modified="2018-07-18" version="1">MPELSSTQTIPKVGAVPKHVAIIMDGNGRWATQRFMPRVAGHSKGVDAVRTMVEACIEQGIDYLTLFAFSSENWRRPEEEVSILMRLFMTALEREVNRLHANDICLKVVGDLSRFSEALQEKIRDAESKTANNKRLTVTICANYGGRWDIVQAMNKLLAAQPEITQIEEHHLAPYLSMAYAPEPDLFIRTGGEKRVSNFLLWQLAYTELYFTDTYWPDFGRTELTAAIQSYQHRERRFGRTSEQLLESKKAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXA9</accession>
    <name>A0A2S9GXA9_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_3016</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92357">
        <property type="protein sequence ID" value="PRC92357"/>
        <property type="gene ID" value="S2091_3016"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="4">
        <location>
            <begin position="18"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC92357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="337" mass="38026" checksum="151C1516208BC8B3" modified="2018-07-18" version="1">MAAQNNAPLPDGLEVAGYRIVKKIASGGFSIVYLASDEEGTPVAIKEYLPSSLVLRQLGELAPAISPENLPIYRIGLKCFFEEGRALARISHPNVVSVLNFFRANDTVYMVMAYESGCSLQEHILRRRDKPERPIVTERFIRKMFSQVLNGLREVHTNKLLHLDLKPANIYLRLDGTPILLDFGAARQTLRTDLPKLYPMYTPGFAAPELYEKNANLGPWTDIYSIGAAMFACMAGAPPQPSDQRKVSDKMERHYRKLDESYSAELIEVVRWCLRLDPLERPPSVFALQKALMLKIEEKKEPSLLEKVKLFYAKLMDGINKPKNDELDSKTITGNSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXC7</accession>
    <name>A0A2S9GXC7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Peptidase family M28</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_3034</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Golgi apparatus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Lysosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92375">
        <property type="protein sequence ID" value="PRC92375"/>
        <property type="gene ID" value="S2091_3034"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005764">
        <property type="term" value="C:lysosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070573">
        <property type="term" value="F:metallodipeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039866">
        <property type="entry name" value="CPQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007484">
        <property type="entry name" value="Peptidase_M28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12053">
        <property type="entry name" value="PTHR12053"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04389">
        <property type="entry name" value="Peptidase_M28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015636920" evidence="7">
        <location>
            <begin position="31"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M28" evidence="8">
        <location>
            <begin position="281"/>
            <end position="469"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC92375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="491" mass="52632" checksum="7459426F012DABC2" modified="2018-07-18" version="1">MKMIKQKTLVKLIVVVACSFSAVIVNVAHADTVAVTKANGVDFATLARIRDAAMSSDYSYDRLAELTDQIGPRLSGSLGAEAAVALIADDMRRIGMQVNLQPVKVPHWVRGAETAELVEYPNRPAGISQKVVLTALGGSSATPASGLTLPILVVHSMEELHAHAADVKGRIVLFDVAYDQNLANNGHAGNAYGEAGMYRFIGPATASKLGAAAALVRSVGGADFRIPHTGMTGWGKDATPIPAAAVTAEDAMLMTRLAAKGEIKMHLTLTPQTLPDADSHNVIADLPGSDKSDEVVIVSGHMDSWDLATGATDDGAGLVVAMGVADVFKRLGLHPRRTVRMIGWMNEENGTRGGKAYFNANKDKLNKHFAVIESDSGAGRPMGLIFSTVAEDQKLIEPLKSIFRTIGTPILERREYAGGEDVSQLTDSGVPSFEPMLDTRNYFSYHHTPADTLDKVEPENLRRQVAMLAMLTWYLAEMPEQLQQLAPSKPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXF9</accession>
    <name>A0A2S9GXF9_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 7">Threonylcarbamoyl-AMP synthase</fullName>
            <shortName evidence="7">TC-AMP synthase</shortName>
            <ecNumber evidence="4 7">2.7.7.87</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6 7">L-threonylcarbamoyladenylate synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">S2091_2782</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>ATP + hydrogencarbonate + L-threonine = diphosphate + H2O + L-threonylcarbamoyladenylate</text>
            <dbReference type="Rhea" id="RHEA:36407"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
            <dbReference type="ChEBI" id="CHEBI:73682"/>
            <dbReference type="EC" id="2.7.7.87"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the SUA5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.87" evidence="4 7"/>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92407">
        <property type="protein sequence ID" value="PRC92407"/>
        <property type="gene ID" value="S2091_2782"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003725">
        <property type="term" value="F:double-stranded RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061710">
        <property type="term" value="F:L-threonylcarbamoyladenylate synthase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11030">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017945">
        <property type="entry name" value="DHBP_synth_RibB-like_a/b_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038385">
        <property type="entry name" value="Sua5/YwlC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005145">
        <property type="entry name" value="Sua5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010923">
        <property type="entry name" value="T(6)A37_SUA5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006070">
        <property type="entry name" value="YrdC-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03481">
        <property type="entry name" value="SUA5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01300">
        <property type="entry name" value="Sua5_yciO_yrdC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004930">
        <property type="entry name" value="Tln_factor_SUA5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55821">
        <property type="entry name" value="SSF55821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00057">
        <property type="entry name" value="TIGR00057"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51163">
        <property type="entry name" value="YRDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="YrdC-like" evidence="9">
        <location>
            <begin position="4"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="26"/>
        </location>
        <ligand>
            <name>L-threonine</name>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="49"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="58"/>
        </location>
        <ligand>
            <name>L-threonine</name>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="112"/>
        </location>
        <ligand>
            <name>L-threonine</name>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="135"/>
        </location>
        <ligand>
            <name>L-threonine</name>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="137"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="145"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="181"/>
        </location>
        <ligand>
            <name>L-threonine</name>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="198"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="237"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00015492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029774"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR004930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR004930-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC92407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="351" mass="37124" checksum="3161C325975F3987" modified="2018-07-18" version="1">MPSPSQITQAAEILAAGGLVAFPTETVYGLGADAENPSAVAAIYAAKGRPANHPVIVHLSPEADLSYWVKEIPEEAKKLIAAFWPGPLTLILKRADHIPDAVSGGQDSIGVRCPSHPVAQALLRAFKNGQGGIAAPSANKFGRVSPTTAQHVRDEFATELQTGGLVKAVLEGEQSEVGIESTILDLTRLGTHGPVLLRPGHICIDQLAAVLGAMPVSPDVASDVSTPRASGTLEAHYAPHTPVVIVTSEQLISTLQQLHNVNKKVALLHYSTQNQGNLCTELSAEINLPNHPAKYAHELYASLRQLDAASADVIVVQALPDTTEWHGVRDRLRRAAHDSLGVLANLLAKQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXJ0</accession>
    <name>A0A2S9GXJ0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Tetratricopeptide repeat</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2804</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92429">
        <property type="protein sequence ID" value="PRC92429"/>
        <property type="gene ID" value="S2091_2804"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015547248" evidence="2">
        <location>
            <begin position="22"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="195"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="422" mass="46362" checksum="2833D8C3CA15DA4E" modified="2018-07-18" version="1">MKIKCLILSVCGFCFFNTGWAQDVPTSDPASAVAQSDSAEDNLQLQLVNEGAKLVASGKSAEAISNYFDKVIATYEAKYGNSKIKIYSARSSTESLAYMLEAANNKVSAKVVSSVWSMAFFLKSYALIEIHRPADSYPFLDKALEMSPKNSHFLSELGNRYQNQKNWTKALETYQLAEEAAKGFSPENSKKIDLGQAWRGLAFVYVEQNRLDEAEAIYLKCLELSSADSAAARELKYVRGLKAKHAGLQNLVPYTHMPTGIVFPVKVENYQLSQIQNLELSQPGQGIKISYVNPDNFNAEISVFNSGLTPMPTSATDPAIQNLRNKEVDSLLNQAKSVGGPGAVLPRKTISLAGSWPTANGKIDLLSDAFIVYPQGRATNDNLYIWIAKGFIWKVRVTKVAGTLTSETPVNFLKYVMELSAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXP6</accession>
    <name>A0A2S9GXP6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2870</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92495">
        <property type="protein sequence ID" value="PRC92495"/>
        <property type="gene ID" value="S2091_2870"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0110165">
        <property type="term" value="C:cellular anatomical entity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006146">
        <property type="entry name" value="5'-Nucleotdase_CS"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00785">
        <property type="entry name" value="5_NUCLEOTIDASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015715166" evidence="1">
        <location>
            <begin position="21"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="51" mass="5382" checksum="11F249172417556B" modified="2018-07-18" version="1">MKLPCLTVISALVLSSCSTVTPVTSTTATGTNTRLALLETTDIHANLRSYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXT4</accession>
    <name>A0A2S9GXT4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">HxlR-like helix-turn-helix</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2893</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92518">
        <property type="protein sequence ID" value="PRC92518"/>
        <property type="gene ID" value="S2091_2893"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002577">
        <property type="entry name" value="HTH_HxlR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01638">
        <property type="entry name" value="HxlR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51118">
        <property type="entry name" value="HTH_HXLR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH hxlR-type" evidence="2">
        <location>
            <begin position="11"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="165"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="184" mass="20439" checksum="CFB0C983705E57F7" modified="2018-07-18" version="1">MRSKGFDGMVCSIAGVLAAIGDRWGLLILRDLFFGISRYDDFRLSSGVTNATLSNRLKHLEANGLIERQLYQSNPPRYEYLLTQKGRDVAPVLAMLAELGDRWDVSGATEPPLMFVNRKSGAPVRWMPIDQNTDEQLSTSDVMFKEGPGADDLVRWRLSYAESSDVVGDKLAAQSRAASKPTKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXV9</accession>
    <name>A0A2S9GXV9_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ribosome biogenesis GTPase A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_2604</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92549">
        <property type="protein sequence ID" value="PRC92549"/>
        <property type="gene ID" value="S2091_2604"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023179">
        <property type="entry name" value="GTP-bd_ortho_bundle_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019991">
        <property type="entry name" value="GTP-bd_ribosome_bgen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016478">
        <property type="entry name" value="GTPase_MTG1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006230">
        <property type="entry name" value="MG442"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03596">
        <property type="entry name" value="GTPase_YlqF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1 2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="G" evidence="3">
        <location>
            <begin position="110"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="51"/>
            <end position="54"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="117"/>
            <end position="122"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="161"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR006230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR006230-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC92549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="308" mass="33684" checksum="2733F15CD33D00A0" modified="2018-07-18" version="1">MNAARKKAAETMENTDLVIEVLDARIPQASCNPMVEQLRNFRQRPCLKILNKSDLADPDSTAAWLAFYNAQKGVKAVALSCKKPADVAKITGYCLALAPHRAVPTKPLRMMIMGIPNVGKSTMMNALLKKRVAPVGDEPAVTKVQQRLYLGKNMILTDTPGMLWPKIAHPTDGLMLAASHAVGVNALIEEEVATFLAELVLQRYPQFLVARYGMNTDGIDAVSVIEGVAKKRGYRLKGGEWDFEKAAHTLLLDYRSGALGRVSLETPQSREILLANYVPPVLLGQGKVTDTEVGEQGRDTIFTDSGRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GY06</accession>
    <name>A0A2S9GY06_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Elongation factor 4</fullName>
            <shortName evidence="6">EF-4</shortName>
            <ecNumber evidence="6">3.6.5.n1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Ribosomal back-translocase LepA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">lepA</name>
        <name evidence="8" type="ORF">S2091_2660</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>GTP + H2O = GDP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="EC" id="3.6.5.n1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Peripheral membrane protein</topology>
            <orientation evidence="6">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.n1" evidence="6"/>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92605">
        <property type="protein sequence ID" value="PRC92605"/>
        <property type="gene ID" value="S2091_2660"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045727">
        <property type="term" value="P:positive regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03709">
        <property type="entry name" value="lepA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2570">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00071">
        <property type="entry name" value="LepA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006297">
        <property type="entry name" value="EF-4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000640">
        <property type="entry name" value="EFG_V-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038363">
        <property type="entry name" value="LepA_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013842">
        <property type="entry name" value="LepA_CTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035654">
        <property type="entry name" value="LepA_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43512">
        <property type="entry name" value="PTHR43512"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00679">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06421">
        <property type="entry name" value="LepA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00838">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="SSF54980"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01393">
        <property type="entry name" value="lepA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="7">
        <location>
            <begin position="2"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="14"/>
            <end position="19"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="131"/>
            <end position="134"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC92605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="597" mass="65701" checksum="C2F7BC072BEC42BB" modified="2018-07-18" version="1">MNNIRNFSIIAHIDHGKSTLADRIIQLCGGLSDREMEAQVLDSMDIERERGITIKAQTAALNYKARDGQIYNLNLIDTPGHVDFSYEVSRSLSACEGALLVVDASQGVEAQTVANCYTAIELGVEVVPVLNKIDLPSADPENACNEIEEVIGIDASDAVHCSAKTGLGVIDVIESLIAKVPPPKGDVDAPLQALIVDSWFDNYVGVVMLVRVMNGTLRPKDKILLMANGSQHLVESVGVFTPKSINRDSLRAGQVGFIIAGIKELKAAKVGDTVTLLSKPAAQPLPGFKEVQPQVFAGLFPVEANQYEALRDSLEKLKLNDAALQYEPEVSQALGFGFRCGFLGLLHMEIVQERLEREFDMDLITTAPTVIYEVVQGDGSILLVDNPSKMPDPSRIEEVREPIVTVNLYMPQEYVGAVITLCTGKRGVQLDMNYHGRQVKLTYEIPMAEIVLDFFDRLKSTSRGYASMDYEFKEYRAADVVKVDMLINGEKVDALAIIVHRANSNYRGRAVAAKMRELIPRQMFDVAIQAAIGANIISRENVKALRKNVLAKCYGGDISRKRKLLEKQKAGKKRMKQVGSVEIPQEAFLAILQVEDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GY22</accession>
    <name>A0A2S9GY22_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HNH endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2679</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92624">
        <property type="protein sequence ID" value="PRC92624"/>
        <property type="gene ID" value="S2091_2679"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00085">
        <property type="entry name" value="HNHc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002711">
        <property type="entry name" value="HNH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003615">
        <property type="entry name" value="HNH_nuc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01844">
        <property type="entry name" value="HNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HNH" evidence="1">
        <location>
            <begin position="102"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="165" mass="18410" checksum="79A8A22BAC8A2648" modified="2018-07-18" version="1">MTTWSKNQITLKLDQFRNWLSANGAELLQPTNEYELVRFRAGDKTGIIYWNTKGGSSFVQPALEAWEAFKGAHSWRAAPATTRRKKSSVTLQAVRARDGSHCFYCLSPVLVEDESEEHLVSITHGGPNHISNIFLAHKLCNARAGNLSAPEKIALHVAQYMNVKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GY30</accession>
    <name>A0A2S9GY30_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC-type sugar transport systems permease component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_2621</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92566">
        <property type="protein sequence ID" value="PRC92566"/>
        <property type="gene ID" value="S2091_2621"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008643">
        <property type="term" value="P:carbohydrate transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="73"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="106"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="156"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="214"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="265"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="69"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC92566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="295" mass="33034" checksum="8C4C08E425A24221" modified="2018-07-18" version="1">MASRSASTFSPWLLILPSFALALFIVSYPFFNIVYQSLHEVSRFGVVRDFTGLTNFVTIFSDPVFIETLYRTLIWTLCVVGGTILVAVPTALILSQDFYGRGIARAISMLPWSISLTMTAIIWRWAFNTEFGMVNLGLLQLGLIHEPVQWLADPSLAFPVEILVGILVSVPFTVTIFLGGLSSVPQDIYEAARIEGASSWQQFRKITMPLLRPFINIALVLNVIYVFNSFPIIWVMTQGGPDNSTHILVTYLYELAFRLGRPGEAAAVSLVMLIILFAFTGLYMHIQGREEDQHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYD8</accession>
    <name>A0A2S9GYD8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2464</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92734">
        <property type="protein sequence ID" value="PRC92734"/>
        <property type="gene ID" value="S2091_2464"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="68"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="151" mass="17428" checksum="77E55855DDF58EA9" modified="2018-07-18" version="1">MLDYLKRTYESCLRIDSEGRQGGWATLFRFSKYFAALRRTMFRSAIVLLSVMFAYWGLLKIDLIPQHYSAILCQSALLAGFMWVAFAGMTQSFHDECSRYTKRVEKDVCEQVERLFGSFIFCYVVKLPSDDESFKSRCLPAPFIPPRVASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYE3</accession>
    <name>A0A2S9GYE3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2461</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92731">
        <property type="protein sequence ID" value="PRC92731"/>
        <property type="gene ID" value="S2091_2461"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="135" mass="15047" checksum="F5287FD148989E16" modified="2018-07-18" version="1">MSCIFRVSGDGLDVDALILRNKLAANRIWRRGEPRLLKGRIHSNAGANYIASQADLDQFEIQIQETIVFLEKNLSEILAIACFPGVDDARLDFGVVYQENFVESTYLSPKLLKLIAQAGIGVEISRYASRTDDQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYE5</accession>
    <name>A0A2S9GYE5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2475</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92745">
        <property type="protein sequence ID" value="PRC92745"/>
        <property type="gene ID" value="S2091_2475"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="86" mass="10103" checksum="9F0D7351153F9451" modified="2018-07-18" version="1">MITKETTPVQWAMFMYELEDAKEHLSNLISDINNDPEYDESALRVDLGHIYSHLNRAWYQHKTELDTANQVEFEKASQFPCDLKPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYG3</accession>
    <name>A0A2S9GYG3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acetyltransferase (GNAT) family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2481</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92751">
        <property type="protein sequence ID" value="PRC92751"/>
        <property type="gene ID" value="S2091_2481"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13673">
        <property type="entry name" value="Acetyltransf_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="11"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="183" mass="19916" checksum="74FB3E0F2D8FA791" modified="2018-07-18" version="1">MLSVRGGVSMAIIRQVNQGSVQLLSGLVGLLQDVVHHGASVGFLAPLEQAEANRYWQGVLADLGRGLVLWVAEQDGIVVGAIQLALCGRANGMHRADVQKLFVHSLSRGIGISSQLLYALEAFAKQQRRSLLVLDTEAGSLAEKIYQHWNWQRVGEIPGYAASPDGKLISTCYYYKQVALEDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYN6</accession>
    <name>A0A2S9GYN6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Sulfite reductase beta subunit (Hemoprotein)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_2564</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92834">
        <property type="protein sequence ID" value="PRC92834"/>
        <property type="gene ID" value="S2091_2564"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.413.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005117">
        <property type="entry name" value="NiRdtase/SiRdtase_haem-b_fer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036136">
        <property type="entry name" value="Nit/Sulf_reduc_fer-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006067">
        <property type="entry name" value="NO2/SO3_Rdtase_4Fe4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045169">
        <property type="entry name" value="NO2/SO3_Rdtase_4Fe4S_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045854">
        <property type="entry name" value="NO2/SO3_Rdtase_4Fe4S_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11493">
        <property type="entry name" value="PTHR11493"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01077">
        <property type="entry name" value="NIR_SIR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03460">
        <property type="entry name" value="NIR_SIR_ferr"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55124">
        <property type="entry name" value="SSF55124"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56014">
        <property type="entry name" value="SSF56014"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NIR_SIR_ferr" evidence="5">
        <location>
            <begin position="50"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="domain" description="NIR_SIR" evidence="4">
        <location>
            <begin position="119"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="domain" description="NIR_SIR_ferr" evidence="5">
        <location>
            <begin position="345"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="domain" description="NIR_SIR" evidence="4">
        <location>
            <begin position="453"/>
            <end position="547"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC92834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="564" mass="63913" checksum="FE03B4FD964A9851" modified="2018-07-18" version="1">MYRYDQHDHQIIKERIAQYRDQVRRRLADELTEEEFLPLRLQNGLYMQRHAYMLRIAVPYGMLSSAQLRKFAYIAKTYDRGYGHFTTRQNIQFNWIELEQTPEILEHLASVEMHAIQTSGNCMRNITSDEFAGVAADEIIDTRPYAEILRQWTTFHPEFAYLPRKFKIAINGSKEDRAAIAVHDIGLTVVYNEAGEVGFQVMVGGGMGRTPILGSIIREFLPWQHVITYLEAILRIYNEYGRRDNKYKARIKILVKALGAEEFARQVEEQWADPKDGPATITETEFKRIASYFTHPAYVTLPEQNAEFSAHLAENKAFSNWVRRNVKPHKVAGYRNVVLSLKKPGVPPGDATTEQMDFIADLADQYSFGELRITHEQNLVLADVQLSELFSLWEAAKAHGLATPNIGLLTDLICCPGGDFCSLANAKSIPIALDITDRFSQLDYLHDIGELDLNISGCINACGHHHVGNIGVLGVDKDGSEWYQVSIGGTQGINAAIGKIIGPSFAAAQMPEVIERLIKVYLRERFEDEKFIDTVQRLGITPFKEFVYATPIHSTVLHGEDEYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYP4</accession>
    <name>A0A2S9GYP4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2577</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92847">
        <property type="protein sequence ID" value="PRC92847"/>
        <property type="gene ID" value="S2091_2577"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="27"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="81" mass="9348" checksum="53C6BA163CFD18ED" modified="2018-07-18" version="1">MTLGMFVTAFAFYCMFTAIPKYRNSKYFRIMLLAIIIVFTLAISLSPKEIDLIYRLMLGFGYGLMIVIFGIYVAKQRNKKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYS6</accession>
    <name>A0A2S9GYS6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Prepilin-type N-terminal cleavage/methylation domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2278</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92861">
        <property type="protein sequence ID" value="PRC92861"/>
        <property type="gene ID" value="S2091_2278"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="164"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="232" mass="25374" checksum="5466DA629F9F760A" modified="2018-07-18" version="1">MRCKMKSQGFTLIELLVAISILAIVAVLGWRGLDSIVRSREVLTAELEQTRGLQLTFAQLQSDCAQNVNPFNYPNLPEGRSSWIEPQRLILIRNVFSDDQAPAMQVVTYRLQNSTITRFESISTRDLTVLTQLLAQARNPPDQQVEIVMQKKVQSVEFTGYPDSSVAANSTTSTAGNTNSTNSPGNPAPGNQPVNNGVQNVNQANATTGLQVSLQLQNNDKNMLKIFILGGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYX4</accession>
    <name>A0A2S9GYX4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2352</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92935">
        <property type="protein sequence ID" value="PRC92935"/>
        <property type="gene ID" value="S2091_2352"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014993">
        <property type="entry name" value="DUF1841"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08897">
        <property type="entry name" value="DUF1841"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="142" mass="16216" checksum="6CC9CF05D8E82C45" modified="2018-07-18" version="1">MFNPTQDDVRRFFCETYRKSLAREILTPLESIASDWIMQHPEYESELADLNAALEADYSVDQGKPNPFLHLSMHLSIAEQISINQPVGIKAAYLNLAHRLQSEHEAHHVMMECLGAMIWESQRNGMPFDGAAYVEAVQQKLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYX8</accession>
    <name>A0A2S9GYX8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Lactate dehydrogenase and related dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_2359</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92942">
        <property type="protein sequence ID" value="PRC92942"/>
        <property type="gene ID" value="S2091_2359"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006139">
        <property type="entry name" value="D-isomer_2_OHA_DH_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029752">
        <property type="entry name" value="D-isomer_DH_CS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006140">
        <property type="entry name" value="D-isomer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00389">
        <property type="entry name" value="2-Hacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02826">
        <property type="entry name" value="2-Hacid_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00065">
        <property type="entry name" value="D_2_HYDROXYACID_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2-Hacid_dh" evidence="3">
        <location>
            <begin position="15"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="domain" description="2-Hacid_dh_C" evidence="4">
        <location>
            <begin position="111"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC92942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="324" mass="35579" checksum="57C230F6990B0A4F" modified="2018-07-18" version="1">MSKPAVLLTCIAFPEIIEQLSVHFELETNQQDATFTEQELIAQLQNKQAVFTAGNARFTEHVLQHAPQLKLICAMTVGYDNIDVAACAKRGIVVTNAPDVLNQTTADFAWALLLATARRVTESEHWLRAGHWQKWSLDGFLGADVHGKTLGILGMGRIGQAIARRSMGFDMQVLYHNRSRLTPAQEAHSNNASYVSKQELLKSVDHLILMLPYSAATHHCMGAEEFSQMRSSATLINVARGGVVDDAALILALRNQQIAAAGLDVYENEPRLNPEFLGLPNVVLTPHIASATEPTRRAMQQCAVNNLIAYFERGEVINLVASVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYY5</accession>
    <name>A0A2S9GYY5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2337</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92920">
        <property type="protein sequence ID" value="PRC92920"/>
        <property type="gene ID" value="S2091_2337"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="56"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="84"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="134"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="180" mass="19697" checksum="4B77264BA6AB29E6" modified="2018-07-18" version="1">MKKNEAKKIALEMLGTGESKKSVFEKLTGEGMSGRFIANIIASYANPGLCEKYKGLIKAVIVIAYVQVLVGLVAGFVYGGQYGAIGGLVGAILGAAWTLLFAWGFTQNKAWAYNVTILLSVIQVPKQISNFEKAPIYIGTMISISCALIFFYFYVRTKIFPDYAGLFSIKKLNGAYEFKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZE7</accession>
    <name>A0A2S9GZE7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phage terminase-like protein large subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2164</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93078">
        <property type="protein sequence ID" value="PRC93078"/>
        <property type="gene ID" value="S2091_2164"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005021">
        <property type="entry name" value="Terminase_largesu_Lambdalike"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41287">
        <property type="entry name" value="PTHR41287"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03354">
        <property type="entry name" value="Terminase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="575" mass="63933" checksum="39897B7DF57E9CC4" modified="2018-07-18" version="1">MEKIKPPRISDRATDYAKKVVSGKILAGQHIRAACKRHIDDIKTGAARGLKWDKALAARAIGYFENVLCLNGGEYEGLPFILLDWQAFIVGSLFGWIGDDGYRRFRVAYVETAKGSGKSPLAAGVGLYGMTSDGESRAEVYAAATKKDQAQILFRDAVAMVDQSPHLNRRIERSGSKGKEWNLAHQASASFFRPISSDEGQSGPRPHIALLDEIHEHRNAHAVEMMRAGTKSRRQALIFMITNSGTDKRTVCWDYHDYGAKVSAGQLKDDSFFAYICSIDEGDNPFKDEKCWYKANPSLKDGIPGLKYLREQVTQARGMPSKESLVRRLNFCEWTEAISPWISSESWFICEQNPLIPLEQFYGRSGVAGLDLSSTTDLTALVVALDPTEDDPVTRIIPYFWLPGDGLHDKADKDRVPYLAWRDAGHLEALPGKAIDKLAVLNRISLLTAMFNLREIACDRWRLEDFQQMVDREGVALPPLTPFGQGFKDMAPAIDEFESMLLDQRLMHNGNPVMTWNAANAVLMTDPAGNRKLAKERATGRIDGMVAAVMAIGCAMRGLAVKPPSVYETRGIRML</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZF5</accession>
    <name>A0A2S9GZF5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_2205</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S66 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93119">
        <property type="protein sequence ID" value="PRC93119"/>
        <property type="gene ID" value="S2091_2205"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10740">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027461">
        <property type="entry name" value="Carboxypeptidase_A_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027478">
        <property type="entry name" value="LdcA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040449">
        <property type="entry name" value="Peptidase_S66_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040921">
        <property type="entry name" value="Peptidase_S66C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003507">
        <property type="entry name" value="S66_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30237">
        <property type="entry name" value="PTHR30237"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02016">
        <property type="entry name" value="Peptidase_S66"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17676">
        <property type="entry name" value="Peptidase_S66C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028757">
        <property type="entry name" value="LD-carboxypeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141986">
        <property type="entry name" value="SSF141986"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_S66" evidence="4">
        <location>
            <begin position="4"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S66C" evidence="5">
        <location>
            <begin position="165"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="3">
        <location>
            <position position="101"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="3">
        <location>
            <position position="196"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="3">
        <location>
            <position position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR028757-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF17676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC93119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="303" mass="33544" checksum="21092047493B8BA1" modified="2018-07-18" version="1">MPTIAIIGPSAYAPNPDYVPRAIARLQERGWKIKNLVDPNSKYQRFSADDATRLAQLYSAAEDPEVDVVLALRGGYGLSRLLDDIDFQRLANSGKLFVGFSDFTAFHLGMLAKTGAISFAGPMLYDDFGQEQLYESSFQYFKDCLTTANYHLNVVVEGNPTVHAQGKFWGGNLAMLAHLVGSSFMPKIEGGILFVEDVNENPYRVERMLLQLHHAGILANQKALVLGHFTNYCASEYDNGYDFNAMLDFIRSKISIPIITGLPFGHCPNKATFPIGAQISLTSDVNGFTLQFEKYPHLSLQNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZP5</accession>
    <name>A0A2S9GZP5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HutF: formiminoglutamate deiminase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1939</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93201">
        <property type="protein sequence ID" value="PRC93201"/>
        <property type="gene ID" value="S2091_1939"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010252">
        <property type="entry name" value="HutF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43608">
        <property type="entry name" value="PTHR43608"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="SSF51338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02022">
        <property type="entry name" value="hutF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydro-rel" evidence="1">
        <location>
            <begin position="50"/>
            <end position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="456" mass="50763" checksum="157F469E12392D5E" modified="2018-07-18" version="1">MSINTTLFARNVWLADGWAENVRLHWNASGDLTQIEHNASAALHEVIEQFVLPGMVNLHSHAFQRAMAGMTEIAGEGPDSFWTWRDLMYRFALAINPEQIQAIAAQLYSECLRHGYTSVCEFHYLHRAPDGAFYANMAETAQRVMAAAQATGIGMTMLPVLYSYADFNQQPLRHEQRRFATNPEQILQLVELLEPLRNGQTEVGVAPHSLRAASTQQISELVQALPPQRPIHIHIAEQQKEVDSCVAFSGKRPVELLFDTQTVNERWCLVHATHLSDGEVTQIANSRAVAGICTSTEGNLGDGFFLLPDYIAQQGRFGIGSDSHVSQSPIEELRWLEYGQRLRAQRRNMSSVAGQRRIGDFLWQASLEGGAQASGRKVGSLAAGMRADLLVLDANHPNLSGIAASELLNNWIFSGNDNLVRDVLVGGQWRVKKGQHLHQDAIQGRFKQTMRELRAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZV8</accession>
    <name>A0A2S9GZV8_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase</fullName>
            <ecNumber evidence="10">2.1.1.14</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Cobalamin-independent methionine synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Methionine synthase, vitamin-B12 independent isozyme</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">metE</name>
        <name evidence="13" type="ORF">S2091_1971</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 10">Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>5-methyltetrahydropteroyltri-L-glutamate + L-homocysteine = L-methionine + tetrahydropteroyltri-L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:21196"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:58140"/>
            <dbReference type="ChEBI" id="CHEBI:58199"/>
            <dbReference type="ChEBI" id="CHEBI:58207"/>
            <dbReference type="EC" id="2.1.1.14"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="10">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 10">Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-methionine from L-homocysteine (MetE route): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the vitamin-B12 independent methionine synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.14" evidence="10"/>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93233">
        <property type="protein sequence ID" value="PRC93233"/>
        <property type="gene ID" value="S2091_1971"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00051">
        <property type="reaction ID" value="UER00082"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003871">
        <property type="term" value="F:5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009086">
        <property type="term" value="P:methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03311">
        <property type="entry name" value="CIMS_C_terminal_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.210">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00172">
        <property type="entry name" value="Meth_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013215">
        <property type="entry name" value="Cbl-indep_Met_Synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006276">
        <property type="entry name" value="Cobalamin-indep_Met_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002629">
        <property type="entry name" value="Met_Synth_C/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038071">
        <property type="entry name" value="UROD/MetE-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08267">
        <property type="entry name" value="Meth_synt_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01717">
        <property type="entry name" value="Meth_synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000382">
        <property type="entry name" value="MeTrfase_B12_ind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51726">
        <property type="entry name" value="SSF51726"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01371">
        <property type="entry name" value="met_syn_B12ind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 10" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="4 10 13" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0677">Repeat</keyword>
    <keyword evidence="6 10 13" id="KW-0808">Transferase</keyword>
    <keyword evidence="8 10" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Meth_synt_1" evidence="12">
        <location>
            <begin position="4"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="domain" description="Meth_synt_2" evidence="11">
        <location>
            <begin position="431"/>
            <end position="752"/>
        </location>
    </feature>
    <feature type="region of interest" description="5-methyltetrahydropteroyltri-L-glutamate binding" evidence="10">
        <location>
            <begin position="16"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="region of interest" description="L-homocysteine binding" evidence="10">
        <location>
            <begin position="435"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="region of interest" description="L-methionine binding" evidence="10">
        <location>
            <begin position="435"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="region of interest" description="5-methyltetrahydropteroyltri-L-glutamate binding" evidence="10">
        <location>
            <begin position="519"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="10">
        <location>
            <position position="698"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="116"/>
        </location>
        <ligand>
            <name>5-methyltetrahydropteroyltri-L-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:58207"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="488"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="565"/>
        </location>
        <ligand>
            <name>5-methyltetrahydropteroyltri-L-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:58207"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="603"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="609"/>
        </location>
        <ligand>
            <name>5-methyltetrahydropteroyltri-L-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:58207"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="645"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="647"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="669"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="730"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF08267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PRC93233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="758" mass="85440" checksum="AEE93C8F2127E529" modified="2018-07-18" version="1">MVTTHNLGFPRIGAKRELKFALENYWKGDVTLDQLAETGAQLRQRHWQNQSALDLVPVGDFSFYDQVLDMSFLLGNIPDRVRHLDGNTLDNYFRVARGRSAQDSSCSCVHAGEMTKWFDTNYHYIVPELSAETEFSLDASRLLAQLAQARQLKVSAKPVIIGPLTYLWLGKTRDASDKLALLPRLLPAYITLLNQLAEQGCEWVQIDEPILVTELDASWQQAFIAAYDALQAGSAKLLLATYFGQLKDNLPLLCKLPVQGIHIDAINGQDEIGQLIQQLPADTVLSLGVINGRNIWKTDLHATLEWLEPVHRLLQTRLWIAPSCSLLHVPVDLSSEQKLDSRIQYWLAFALQKLDELQILAKALNNGRVSVQEELIANHVAIERRRTSSLVHNPAVKAAIAKIDATLGKRNSAYEQRAIKQSALLKLPDYPTTTIGSFPQTTEIRQARNQFRLGNLDEVAYKALMQNEIARCVREQEALGLDVFVHGEAERNDMVEYFGEQLEGYAFSQFGWVQSYGSRCVKPPILFGDISRPKAMTVEWIKYAQSLTDKPMKGMLTGPVTILNWSFVRDDQPRSVSCYQLALAIREEVLDLEQAGVRVIQIDEAALREGLPLRRSQWSEYLQWAVESFRITANGVQDETQIHTHMCYSEFNDIIASIANMDADVITIETSRSAMELLDAFDDFNYPNQIGPGVYDIHSPNIPNQEHIVQLMRKAAERIPAQRLWVNPDCGLKTRAWEEVIPALKNMVAAARVLRAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZZ3</accession>
    <name>A0A2S9GZZ3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphocarrier, HPr family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2025</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93287">
        <property type="protein sequence ID" value="PRC93287"/>
        <property type="gene ID" value="S2091_2025"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00367">
        <property type="entry name" value="PTS-HPr_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1340.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000032">
        <property type="entry name" value="HPr-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035895">
        <property type="entry name" value="HPr-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001020">
        <property type="entry name" value="PTS_HPr_His_P_site"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00381">
        <property type="entry name" value="PTS-HPr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00107">
        <property type="entry name" value="PHOSPHOCPHPR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55594">
        <property type="entry name" value="SSF55594"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01003">
        <property type="entry name" value="PTS_HPr_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51350">
        <property type="entry name" value="PTS_HPR_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00369">
        <property type="entry name" value="PTS_HPR_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HPr" evidence="1">
        <location>
            <begin position="1"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="89" mass="9647" checksum="A2B184579EFC998D" modified="2018-07-18" version="1">MVQVELEIVNKLGLHARASAKFTQLASKYASEVWVMRNNKRVNGKSIMGVMMLAAGKGSRITLETTGTDEQECSTAIATLIAEKFGEGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H043</accession>
    <name>A0A2S9H043_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2075</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93337">
        <property type="protein sequence ID" value="PRC93337"/>
        <property type="gene ID" value="S2091_2075"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="130" mass="14898" checksum="B9DA227C85135128" modified="2018-07-18" version="1">MAKSKQEPLCPCGLGPTYESCCGRYISGAELAPDAEALMRSRYTAYTLENEVYLQKSWHPSTRLKEVMREQDSCKWISLKVLSHHQEQLTATVEFIAKYKINGRAEQLHETSRFVCEGGQWLYKDGVFSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H072</accession>
    <name>A0A2S9H072_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Thiamine-monophosphate kinase</fullName>
            <shortName evidence="2">TMP kinase</shortName>
            <shortName evidence="2">Thiamine-phosphate kinase</shortName>
            <ecNumber evidence="2">2.7.4.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">thiL</name>
        <name evidence="5" type="ORF">S2091_1754</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + thiamine phosphate = ADP + thiamine diphosphate</text>
            <dbReference type="Rhea" id="RHEA:15913"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:37575"/>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.16"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; thiamine diphosphate biosynthesis; thiamine diphosphate from thiamine phosphate: step 1/1.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="2">Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the thiamine-monophosphate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.16" evidence="2"/>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93367">
        <property type="protein sequence ID" value="PRC93367"/>
        <property type="gene ID" value="S2091_1754"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00060">
        <property type="reaction ID" value="UER00142"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009030">
        <property type="term" value="F:thiamine-phosphate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009228">
        <property type="term" value="P:thiamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009229">
        <property type="term" value="P:thiamine diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02194">
        <property type="entry name" value="ThiL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.650.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02128">
        <property type="entry name" value="TMP_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010918">
        <property type="entry name" value="PurM-like_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036676">
        <property type="entry name" value="PurM-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016188">
        <property type="entry name" value="PurM-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036921">
        <property type="entry name" value="PurM-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006283">
        <property type="entry name" value="ThiL"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30270">
        <property type="entry name" value="PTHR30270"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00586">
        <property type="entry name" value="AIRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02769">
        <property type="entry name" value="AIRS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005303">
        <property type="entry name" value="Thiam_monoph_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55326">
        <property type="entry name" value="SSF55326"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56042">
        <property type="entry name" value="SSF56042"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01379">
        <property type="entry name" value="thiL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 5" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0784">Thiamine biosynthesis</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AIRS" evidence="3">
        <location>
            <begin position="27"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="domain" description="AIRS_C" evidence="4">
        <location>
            <begin position="148"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="28"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="43"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>4</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="44"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="45"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="52"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="73"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="119"/>
            <end position="120"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="120"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="144"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="209"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="211"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="212"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>5</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="259"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="315"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC93367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="320" mass="34348" checksum="A01CD2BB39E20F88" modified="2018-07-18" version="1">MSEFELIQHYFTERQSSPSYIPLGIGDDCALMSARVGMQLAISSDMLVAGRHFFADANPRMLGHKSLAVNLSDLAAMGAEPRAFTLALALPEVQPDWLRDFSEGMFFLAEQHHCQLIGGDTTKGPLNICITVFGEVPIGQALRRDAAQAGDDIWVSGALGDARLALAGYLKQQALSEADHQQAALRLHQPSPRITLGLALRGIAHAAIDVSDGLIGDLGHILKRSQLGATLWCDSLPFGPILAQQNTALCREYALAGGDDYELCFTAPSAQRSAVLAAAKQADTVVTRIGYIEAEAGLRIVDANNQPLSLSHQSFDHFSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0N9</accession>
    <name>A0A2S9H0N9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Polysaccharide chain length determinant protein, PEP-CTERM locus subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_1915</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93528">
        <property type="protein sequence ID" value="PRC93528"/>
        <property type="gene ID" value="S2091_1915"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032807">
        <property type="entry name" value="GNVR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014345">
        <property type="entry name" value="PEP-CTERM_polysacc_chain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13807">
        <property type="entry name" value="GNVR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03007">
        <property type="entry name" value="pepcterm_ChnLen"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="423"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="483"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="domain" description="GNVR" evidence="3">
        <location>
            <begin position="361"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="168"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC93528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="508" mass="56869" checksum="C1C1C5D57162F6BF" modified="2018-07-18" version="1">MGDQVKQLQSLFRGGWKYRWYAVSIAWLISVIGFVVIYKLPDNYQSSARVFVDTQSILKPLLSGMTSVPNVEQQVSIMSRTLLSRPNIERVMRMVDLDLTTNNGKDREKLIDTLVSSIKISSTTQNDIYSITYNDESPKVAKDVVQSLLTIFVEGSLGDERQDSEKAILFIDNQIKIYEEKLAAAENALKEFKLKNIGLLPRQGTDSGSKLMDITENLNQSRLELAEAEQGRDAIKKQIASIELPPKTDETPVAVPNPEIDDRIQSVTKNLDSLRLQFTEEHPDIISSKRLLAQLQARKQEEAKMKKPEAANLSANPLFQQLKVSLAAAEAKVASMHARVEEYSSRSARLKALTVAGPEVESQLAQLNRDYLINKENYEKLVASRESAKISSDLSATTQMMTFRVIDPPTAPLSPVGPNRLKLFSIIFVAALILGVLGSVLMSKIRPTFLTQFDLVEATGLTILGSVSMNWTELEKVRRKRSMYAFVLSFFVLLVFYSAMMTTIYIST</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0R4</accession>
    <name>A0A2S9H0R4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphatidylserine/phosphatidylglycerophosphate/ cardiolipin synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1575</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93574">
        <property type="protein sequence ID" value="PRC93574"/>
        <property type="gene ID" value="S2091_1575"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019637">
        <property type="term" value="P:organophosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025202">
        <property type="entry name" value="PLD-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001736">
        <property type="entry name" value="PLipase_D/transphosphatidylase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13091">
        <property type="entry name" value="PLDc_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00155">
        <property type="entry name" value="PLDc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50035">
        <property type="entry name" value="PLD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PLD phosphodiesterase" evidence="1">
        <location>
            <begin position="107"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="PLD phosphodiesterase" evidence="1">
        <location>
            <begin position="292"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="389" mass="43928" checksum="00992A54FBE50099" modified="2018-07-18" version="1">MGLQRNVIFTEQNQLTLLNSGGEFFPALISAIDSAQVEIYLETYLFSEDITGKLVHDALCRAAQRHVSVYVIVDWLGTGNTRSAELGRSFTACGVQFRRFNPWFRRGFARTHRKLFVADQRLAIIGGININHDLFAEGEHKRTLPFPRWDFATSVSGPLVAEIHQLMSDQWKKVGKLDWLKRLELLTAKKAATAQPRAPIVAGLAPRDNFLYRRTIQKAYLYALGNARHQAIIATPYFAPGRKFRNALISAARRGVQVTLLIGCGDFRLQDAVAHSYYPKLLKHGVQIVEYRKSQLHAKVAVVDNEWATIGSCNCDGLSLFINQEANILIKDHEFSSQLSAAILQGVADGVKINLADYENISWQRKFWYGCSFFIYSSIIRLIAVEDFM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0S3</accession>
    <name>A0A2S9H0S3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative membrane-associated protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_1583</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the DedA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93582">
        <property type="protein sequence ID" value="PRC93582"/>
        <property type="gene ID" value="S2091_1583"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032818">
        <property type="entry name" value="DedA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032816">
        <property type="entry name" value="SNARE_assoc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30353">
        <property type="entry name" value="PTHR30353"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09335">
        <property type="entry name" value="SNARE_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="21"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="68"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="154"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="187"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU367016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC93582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="214" mass="23624" checksum="5BDAF11E847C10B1" modified="2018-07-18" version="1">MDFMQFFNMILHVDKTLGLFIAQYGTLIYVILFAIVFCETGLIVLPFLPGDSLLFIAGTFCATGAIDPWLLCVLLITAAILGNTVNYWVGSAIGHKVYERDYAWLDKDALKKTHSFYEKHGGKTIVLARFIPIVRTFAPFVAGVSDMTHKNFQIFNVIGAVIWVVLLVMAGFFLGDIPILRDHLNTVVLIGVGAAVVPLLLGAAWKLFKNLTAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0X2</accession>
    <name>A0A2S9H0X2_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">YceI domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1635</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93634">
        <property type="protein sequence ID" value="PRC93634"/>
        <property type="gene ID" value="S2091_1635"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007372">
        <property type="entry name" value="Lipid/polyisoprenoid-bd_YceI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036761">
        <property type="entry name" value="TTHA0802/YceI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04264">
        <property type="entry name" value="YceI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00867">
        <property type="entry name" value="YceI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101874">
        <property type="entry name" value="SSF101874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015599731" description="YceI domain-containing protein" evidence="1">
        <location>
            <begin position="26"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="domain" description="YceI" evidence="2">
        <location>
            <begin position="29"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="190" mass="20340" checksum="1757842E27F45619" modified="2018-07-18" version="1">MTNSFKKIAATSIVAALLVSSLAYASLAALKFDAKNSNVSITIKQMNVPISAKFTKLNAVIDYNPSAPDTAKAGVEIEIASFDLGDPDYNKEVLKKEWFNAAQFPKASFVSTSMKSAANGTLTATGKLTIKGKTVDVSFPVSIKKEGSNQVFDGVLPIKRLTFNIGEGDWKDTSMVADEVVIKFHVVAAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H176</accession>
    <name>A0A2S9H176_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1701</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93700">
        <property type="protein sequence ID" value="PRC93700"/>
        <property type="gene ID" value="S2091_1701"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="42" mass="4779" checksum="A58078A8FCF9F540" modified="2018-07-18" version="1">MPLIAIAMRSQKSKNLQTALILATVVAVFFVGIFVKQIWFRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H188</accession>
    <name>A0A2S9H188_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1728</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93727">
        <property type="protein sequence ID" value="PRC93727"/>
        <property type="gene ID" value="S2091_1728"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="87" mass="10362" checksum="E759F13D38C6BFC4" modified="2018-07-18" version="1">MDLRPNIKILLIVFSVEFNQCRTVIFLQKLKKIFATMLFEFSNRILSQICFVLMKKRCFLLLILSKCFKNNGQLLFDAIKNMQLVHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1C4</accession>
    <name>A0A2S9H1C4_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Metallophos domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1751</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93750">
        <property type="protein sequence ID" value="PRC93750"/>
        <property type="gene ID" value="S2091_1751"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP_ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043461">
        <property type="entry name" value="LpxH-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34990">
        <property type="entry name" value="PTHR34990"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallophos" evidence="1">
        <location>
            <begin position="17"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="269" mass="31248" checksum="3C65A9F5E37038D4" modified="2018-07-18" version="1">MNNKGSVSEEEQFDFKLRTIFISDIHLGTKGCQAEVLLDFLKRCNAETYYLVGDIVDGWRLKRSWYWPRSHNDVVQKLLRKARKGSRIIYVPGNHDEFLRHYFDLSFGDVEIKNNPIHETADGKRLLVIHGDQYDNVMLYSRWLAFLGDNAYEMLLRLNQPINKVRRWFGLSHWSLSQYLKLKVKNAVNFISCFEGVVAADAAHQNVDGVVCGHIHHAEIRDINGLTYCNDGDWVESCTALVEHMDGKLEILHWLDHYNQRLSELRVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1Q4</accession>
    <name>A0A2S9H1Q4_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NADPH-dependent 7-cyano-7-deazaguanine reductase</fullName>
            <ecNumber evidence="2">1.7.1.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">7-cyano-7-carbaguanine reductase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="2">NADPH-dependent nitrile oxidoreductase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="2">PreQ(0) reductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">queF</name>
        <name evidence="4" type="ORF">S2091_1405</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>7-aminomethyl-7-carbaguanine + 2 NADP(+) = 7-cyano-7-deazaguanine + 3 H(+) + 2 NADPH</text>
            <dbReference type="Rhea" id="RHEA:13409"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:45075"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:58703"/>
            <dbReference type="EC" id="1.7.1.13"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">tRNA modification; tRNA-queuosine biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.7.1.13" evidence="2"/>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93796">
        <property type="protein sequence ID" value="PRC93796"/>
        <property type="gene ID" value="S2091_1405"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00392"/>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046857">
        <property type="term" value="F:oxidoreductase activity, acting on other nitrogenous compounds as donors, with NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033739">
        <property type="term" value="F:preQ1 synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008616">
        <property type="term" value="P:queuosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1130.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00817">
        <property type="entry name" value="QueF_type2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043133">
        <property type="entry name" value="GTP-CH-I_C/QueF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029500">
        <property type="entry name" value="QueF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029139">
        <property type="entry name" value="QueF_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016428">
        <property type="entry name" value="QueF_type2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14489">
        <property type="entry name" value="QueF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14819">
        <property type="entry name" value="QueF_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004750">
        <property type="entry name" value="Nitrile_oxidored_YqcD_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03138">
        <property type="entry name" value="QueF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-0671">Queuosine biosynthesis</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="QueF_N" evidence="3">
        <location>
            <begin position="17"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="83"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="223"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="active site" description="Thioimide intermediate" evidence="2">
        <location>
            <position position="184"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="2">
        <location>
            <position position="191"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="85"/>
            <end position="86"/>
        </location>
        <ligand>
            <name>NADPH</name>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="252"/>
            <end position="253"/>
        </location>
        <ligand>
            <name>NADPH</name>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF14819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC93796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="278" mass="31142" checksum="671223EE401FF219" modified="2018-07-18" version="1">MQSNTPENSTLGKTAAYVTQYDASLLFPIPRAQKRAEIGLTSTLPFFGLDIWNAYEISWLNLRGKPQIVIATFMVPADSPNIIESKSFKLYLNSFNQTRLADTDALLALLKQDISAGFGASVQIKLTLPAEFSHQRFAELDGLLLDRLDIEVENYHPDVTLLSCDLNASPVEETLVSHLLKSNCLVTGQPDWGSVQIHYVGAPIDQAGLLKYLIGFRNHNEFHEQCVERIFTDILSGCKPQKLAVYARYTRRGGLDINPWRSNFSSNQLPSNLRNARQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1R0</accession>
    <name>A0A2S9H1R0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1506</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93897">
        <property type="protein sequence ID" value="PRC93897"/>
        <property type="gene ID" value="S2091_1506"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032874">
        <property type="entry name" value="DDE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13610">
        <property type="entry name" value="DDE_Tnp_IS240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_Tnp_IS240" evidence="2">
        <location>
            <begin position="75"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="157"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="169"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="237" mass="28228" checksum="BD2C2CD1EE5853F4" modified="2018-07-18" version="1">MNPSKPLYFRHRFPSEIISHCVWLYFRFSLSYRDIEEMMAERGVVVTYETIRNWSKKFGGIYAKRMRSRSKKPNDQWHLDEVYLSINGKTHYLWRAVDQDGEVLDVLGQPRRNKRAAKKFFLKLLKRLQYVPRLIITDKLGSYAAAKAEIMPQIKHTQNKGANNRAENSHQPTRERERQMRRFKSPGHAQRFLATYGVIASFFRPGRHLLSAKNYREIMHRRFTEWSEIVDSGYITQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1U3</accession>
    <name>A0A2S9H1U3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="12">ATPase FliI/YscN family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">S2091_1522</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93913">
        <property type="protein sequence ID" value="PRC93913"/>
        <property type="gene ID" value="S2091_1522"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045261">
        <property type="term" value="C:proton-transporting ATP synthase complex, catalytic core F(1)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030257">
        <property type="term" value="C:type III protein secretion system complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030254">
        <property type="term" value="P:protein secretion by the type III secretion system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020003">
        <property type="entry name" value="ATPase_a/bsu_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004100">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000194">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_nucl-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005714">
        <property type="entry name" value="ATPase_T3SS_FliI/YscN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040627">
        <property type="entry name" value="T3SS_ATPase_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00006">
        <property type="entry name" value="ATP-synt_ab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02874">
        <property type="entry name" value="ATP-synt_ab_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18269">
        <property type="entry name" value="T3SS_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01026">
        <property type="entry name" value="fliI_yscN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00152">
        <property type="entry name" value="ATPASE_ALPHA_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9" id="KW-0139">CF(1)</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-1278">Translocase</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="AAA" evidence="11">
        <location>
            <begin position="158"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PRC93913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="451" mass="48837" checksum="70111283C003291C" modified="2018-07-18" version="1">MEHSLQHYRDAIHKAEFVRRIGHVRRLAGLSIESSGPDVQVGEICEIALRTGKRVLRAEAVGLKDDRVVLMPYGSVHGIGAGSTVIATGQMPQVAVGTELLGRVIDAFGDPLDNKRAPRTTGFRPLKSVPLNPMSRPRVDTILETGVRSIDTMLTIGRGQRVGIFSGSGVGKSTLLGMIARHVQADVNVIALIGERGREVKDFIEKHLGEEGLKRSVVVVATSDQPALARARAAYAATAIAEYFRDAGQHVVLTMDSVTRFAMAKREIGLAVGEPPTARGYTPSVFAELPELCERCGTAESGGTITALYTVLVEGDDFNEPISDMLRATLDGHIVLARRLAQQGHFPAIDVLQSASRLVTDLTTDEELNLIHTMFEGLAAYDQNRQMIAMGAYRSGSSPEIDRAIRLNPTLTRFLRQPESESASRSEALVELRKIAQLAEQIEVTGDSNAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1Z1</accession>
    <name>A0A2S9H1Z1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Gloeo Verruco repeat</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1151</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC93978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93978">
        <property type="protein sequence ID" value="PRC93978"/>
        <property type="gene ID" value="S2091_1151"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022519">
        <property type="entry name" value="Gloeo/Verruco_rpt"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03803">
        <property type="entry name" value="Gloeo_Verruco"/>
        <property type="match status" value="9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015418043" evidence="1">
        <location>
            <begin position="27"/>
            <end position="856"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="856" mass="86326" checksum="716A33DB42C68CE3" modified="2018-07-18" version="1">MKKNSFVTHFQILLLTLLLSSCGGGASSQSQTSTMFTISGTVTGLNPGSQITILNNGADAQTVTSNSGFAFDVAVVRNGSYAVTVGTLTAGQLCHVTNDTGVNVVANVTDVSIVCEAAADTILHNFSGQTPVGPHPSFSLTLGNDGDFYGVTTLGGTSNNGTIYKVTSAGVETVLYSFAGGTLDGTAPSASLTLGNDGNFYGVTKSGGTSNNGTVFKITPAGVESVLYSFSFSAYPYSLTLGNDGNFYGVTTNGGTSNNSGTVFKITPSGVETVLYSFAGGTLDGAVPCASLTLGNDGNFYGVTESGGTSNNGTVFKITPAGVESVLYSFSFSAYPYSLTLGNDGNFYGATAYGGNSNNGGTVFKITPSGVETVLYSFAGGTSDGTNPQTSLTLGSDGNFYGVTSNGGTSNNGTVYKITPAGVETVLYSFAVGTSDSSDPYGSLTLGNDGNFYGVTGGTASVPTQGVPWSYPNFGTIYKITPSGVNTLLYSFTGTAEDGFFPYSSLTIGNNGNFYGVTVEGGNYGYGTAYKITPAGVETVLYSFTGGTSDGIAPCGSLTLGNDGNFYGATSIGGTNGFGTAFKITPAGIETVLYSFSGGTSDGANPQGSLTLGSDGNFYGVTSNGGTNKIGTIYKITPAGIETVLYSFAGGTSDGANPQTSLTLGNDGNFYGVASNGGTSNNGTVYKITPAGIETVLYSFAGGTSDGANPLASLTLGSDDNFYGVTSNGGTSNNGTVYKITPAGIETVLYSFTGGTSDGANPQASLTLGSDGNFYGVTSNGGTSKKGTIYKITPAGVETVLYSFAGGTSDGANPQASLTLGSDGHFYGVTTQGGIFSNIHPIGNTMPAQNGTVFRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H230</accession>
    <name>A0A2S9H230_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ABC-type transport system involved in resistance to organic solvents ATPase component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_1191</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94018">
        <property type="protein sequence ID" value="PRC94018"/>
        <property type="gene ID" value="S2091_1191"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030296">
        <property type="entry name" value="MlaF/Mkl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43023:SF6">
        <property type="entry name" value="PTHR43023:SF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-1278">Translocase</keyword>
    <feature type="domain" description="ABC transporter" evidence="7">
        <location>
            <begin position="15"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="47"/>
            <end position="54"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC94018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="277" mass="29951" checksum="25561A7CB3E5E7D2" modified="2018-07-18" version="1">MSNCKIKPPSVTNLVEIQNLHFAYGDRPILTDLNMQFPRNKVVAVMGGSGSGKTTILRLIGGLIAPNAGQIRLLGEPIAQQNSPALYKQRRNMGMLFQHGALFTDLSVFENVAFPLREHTNMPESLLHDLVLLKLNAVGLRNAAQLKPSEISGGMARRVALARAVALDPQLIMYDEPFAGLDPISMGVTANLIRQLNDALGSTSILVSHDVHESFGIADYVYFLSQGSIVAQGTPAEMLASEHPYVQQFVNARADGPVPFHYPGNTLAQDLGIGARS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H263</accession>
    <name>A0A2S9H263_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1223</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94050">
        <property type="protein sequence ID" value="PRC94050"/>
        <property type="gene ID" value="S2091_1223"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002818">
        <property type="entry name" value="DJ-1/PfpI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01965">
        <property type="entry name" value="DJ-1_PfpI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="1">
        <location>
            <begin position="246"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="353" mass="38595" checksum="4FA536D219CA759C" modified="2018-07-18" version="1">MIILNRNAKKDIDMTKAADRSPKLKLAPRRIVLIAYDDMNLLDLCGPLQVFATANRYLASEKVTGYETIVVSIEGGLITTSAGLQFMTVPVSFLKGLSIDTLIAPGGCAGEEYYAPPALIAWVAKRASSVRRLCSVCTGAFLLAAAGQLTGKRAATHWAWVGRLKRLHTDIDIDADKIFVRDGKVWTSAGVTAGIDLTLALIEEDFGHKIAIDTARQLVMFVKRSGGQSQFSVTLATQTTESGDFGELHAWIAANLHEPLTVERLAERASMAPRTFARTYVKKLGRTPAKTVEMMRLEVACRALEETDLPLKNIAAAAGYGDEQTLRRVFHRQLGVGPAQYRSRFSGHQDVNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2A4</accession>
    <name>A0A2S9H2A4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Siderophore-interacting protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1260</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94087">
        <property type="protein sequence ID" value="PRC94087"/>
        <property type="gene ID" value="S2091_1260"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013113">
        <property type="entry name" value="FAD-bd_9_SIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007037">
        <property type="entry name" value="SIP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039374">
        <property type="entry name" value="SIP_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30157">
        <property type="entry name" value="PTHR30157"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08021">
        <property type="entry name" value="FAD_binding_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04954">
        <property type="entry name" value="SIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="SSF63380"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding FR-type" evidence="1">
        <location>
            <begin position="8"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="242" mass="26730" checksum="962EBD4BB68DC70B" modified="2018-07-18" version="1">MKFKSTTRILIPVEVIQIRDVTPAMRRITVAGDGLHTLVVDKPTQWMKVFFPTNNAMPPTGRAYTIRRFNAADGRMDLDFVLHGDNGPASYWVARAKPGEILSLAGPRSGYDINPSAHRHILIGDATALPAMASIVAVLPPNVQVEMFVEVSDKWEEQVLDSAAQLKTHWLHAGKQPPGTTGQLEQAIKRASFDASDCQYWVGGESSMVRAVLSHLVVERLIPRAMIHSAGYWKLGATDHRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2B4</accession>
    <name>A0A2S9H2B4_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Peptidase S53 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1270</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
        <text evidence="1">Binds 1 Ca(2+) ion per subunit.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94097">
        <property type="protein sequence ID" value="PRC94097"/>
        <property type="gene ID" value="S2091_1270"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04056">
        <property type="entry name" value="Peptidases_S53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015919">
        <property type="entry name" value="Cadherin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030400">
        <property type="entry name" value="Sedolisin_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49313">
        <property type="entry name" value="SSF49313"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="SSF52743"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51695">
        <property type="entry name" value="SEDOLISIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0106">Calcium</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="Peptidase S53" evidence="2">
        <location>
            <begin position="149"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="1">
        <location>
            <position position="260"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="1">
        <location>
            <position position="264"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="1">
        <location>
            <position position="438"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="487"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="488"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="504"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="506"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="873" mass="86824" checksum="5FDB1E1C67B916CE" modified="2018-07-18" version="1">MKIFPELNLVPRGLLLAVSTATFLSACGGGSDTNSRPVSAVDMASGVTTLQLQPSALPTAAAQQVATPGFHVAPVILNAPDTTDAVDNAASARKSPRIQLVPDEFKNVSTRRLTLQALQTIRQTHEIKEENVSVAGMVNPLASTAAVVTYTPAQIRAAYGFPTLPAAGATLTAAQAASLGAGQTIYLIDAMSDPNVAAELAAFNQAFGLPACATTPIASTASLPLSAASKNACQFSVVYSTTSGTMTSTAPAYNSGWATEIALDVQWSHATSPLARIVLIEVPDASLNSLLAGINLANAMGPGAVSMSFGSPEGSWTASVDSSFTVANMSYFAATGDSGAGVIWPSVSTHVMAVGGTSLTYSGSGTRSETGWADTGGGTSAYTAVPSYQNSSVPGMGAQTYRTVADVSFNANPNTGQYLAVISPGSSTVSWLSAGGTSLATPQWAGLVTIANAERALVSKTALGASQTILYDQISNVPASYASAFLDVTQGSDGSCAACIAKVGYDQLTGLGTPNATSLLNILSGTSTAIAAPVVTPASISGTVGTALSFTVSVTAPDAVTYSLSGAPSGMAISSVGAVTWATPVAGTYAVTVSAKDSKTGLSGSGLYTVTIANPTAPVVNGGSISGKVGTALSFTVAVTSPDPLTYTLAQQPSGMTISSAGLVTWATPVAGSYAVTVSVKDTKTGLTGKGVYSIVIAAKAPPTVASANINGTVGVALSFGVTATAPDAVTYTLGSGAPSGMVISSSGEVSWAKPVAGTYAVAVTAKDSVTGLSGTGVYTVTISVKGPVVTAPAMTGQVGKVLTGSIIISDPTATALSVSISGVPMGMTFSVTGLTITATWANPVAGTYSMKVVVTDSAGLSTTVTVPVTVTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2N4</accession>
    <name>A0A2S9H2N4_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Septum site-determining protein MinD</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Cell division inhibitor MinD</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">S2091_0849</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Interacts with MinC and FtsZ.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the ParA family. MinD subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94228">
        <property type="protein sequence ID" value="PRC94228"/>
        <property type="gene ID" value="S2091_0849"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025669">
        <property type="entry name" value="AAA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010223">
        <property type="entry name" value="MinD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025501">
        <property type="entry name" value="MinD_FleN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13614">
        <property type="entry name" value="AAA_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003092">
        <property type="entry name" value="MinD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01968">
        <property type="entry name" value="minD_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_31" evidence="10">
        <location>
            <begin position="3"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010257"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011626"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00025436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00032845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF13614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC94228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="271" mass="29609" checksum="2A8E7B2B2D5BD785" modified="2018-07-18" version="1">MARIIVITSGKGGVGKTTSSASFATGLAMRGHKTAVIDFDVGLRNLDLIMGCERRVVYDLINVVSGEATLRQALIKDKHCDNLFILPASQTRDKDALTEAGVEKVLNDLIHMDFEFIICDSPAGIEHGAIMALTFADEAIVVTNPEVSSVRDSDRILGIIQAKSRRAQNGGEPVKEHLLITRYSPKRVEQGEMLSHVDVQEILRIPLIGIIPESEAVLHASNQGNPAIHIKGSDVSLAYEDVVGRFLGEELPLRFMDYEKPGLLKRIFGAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2T3</accession>
    <name>A0A2S9H2T3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0913</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94292">
        <property type="protein sequence ID" value="PRC94292"/>
        <property type="gene ID" value="S2091_0913"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="341" mass="37408" checksum="39E2B4985A2F13DF" modified="2018-07-18" version="1">MINNWSLTTMFNVNALRKPGTIPAFILFLVLALHGFSVHAELVFRSVEQVDGQQRWSPIKKYSNPSDILYTRGGATAHAEEVRVILSGEVTHRDVESAEIMAKLIKSGKQKIANNTIWFSSNGGDIDAGMELGRQLRALGIDTIVGKNDRCMSACVFAFMGGERRSVAGQLGIHRPFFPFTQDASSRLDQFRHLESTLKNFVEELDFPSSLYEAIMLVPPESVQVVSPADLKRFYLEGISPSSEDRLDAASARRLNLTMFAYLQRKARAPTCAFLDAGQGRCEGRVQETAITAANESAAESAADSLASMSKSELIEAGRTDGSMVQATADAQVVQPFRTNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H345</accession>
    <name>A0A2S9H345_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1026</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94405">
        <property type="protein sequence ID" value="PRC94405"/>
        <property type="gene ID" value="S2091_1026"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044053">
        <property type="entry name" value="AsaB-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34598">
        <property type="entry name" value="PTHR34598"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="292" mass="32993" checksum="7DD293B4FFBA4B6C" modified="2018-07-18" version="1">MNTHLYPHNTVVAAATAITSVDAVLGYMQPTEARPYNYAYEPPAGIAWENYAHDNREVRILDARHATAQSSIHHEGFELLDASSELRDFYDRDTIIRRYYPEVAALACSATGAKQAFVFDHLVRKREADRSKLGFGRSNKGIPATANGRVHNDYSEESGRKRLALVLGVKTAELNRNRYSIVNVWRSINGPVLDTPLAVCNARSIDVADLVCAEVRYPQRVGEIYLLRHSPRHCWSYFSQMNNHEALIFKQYDSQVSGVARFTPHAAFDHPYTPPDAPLRESIEARCLVIYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H353</accession>
    <name>A0A2S9H353_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_0917</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94296">
        <property type="protein sequence ID" value="PRC94296"/>
        <property type="gene ID" value="S2091_0917"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000551">
        <property type="entry name" value="MerR-type_HTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015358">
        <property type="entry name" value="Tscrpt_reg_MerR_DNA-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00376">
        <property type="entry name" value="MerR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09278">
        <property type="entry name" value="MerR-DNA-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00040">
        <property type="entry name" value="HTHMERR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00422">
        <property type="entry name" value="HTH_MERR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00552">
        <property type="entry name" value="HTH_MERR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50937">
        <property type="entry name" value="HTH_MERR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH merR-type" evidence="4">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC94296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="144" mass="15556" checksum="BEB0562F8AC4EAA8" modified="2018-07-18" version="1">MGLDISEVAKRSGISCSALRFYEEKGLITSIGRKGLRRLFAADVLERLALIGLGRAAGFSLEEIESMFVADGQPTINRAALNAKAEEIDSTIQKLSAMRDGLRHAAACSAPNHFECPTFRRLMRAAAVGVIDAPKKKAPRSKLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H399</accession>
    <name>A0A2S9H399_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Fe2OG dioxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_1034</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the iron/ascorbate-dependent oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94413">
        <property type="protein sequence ID" value="PRC94413"/>
        <property type="gene ID" value="S2091_1034"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018655">
        <property type="entry name" value="DUF2086"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09859">
        <property type="entry name" value="Oxygenase-NA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="3">
        <location>
            <begin position="126"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC94413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="239" mass="26953" checksum="82FE95516C40177E" modified="2018-07-18" version="1">MSTNSHKSMPALHLQDWASIEKSLDAGGNAVLPDLLTSAQCEELVVMYSQEERYRSRVVMARHGFGLGEYKYFAYPLPDMLAKLRDELYPHLAIVANRWNQLMGNGMRYPANLHTFIERCHAAGQTRPTPLILKYGEGDYNCLHQDLYGEHVFPLQIAILLARPGEDFTGGEFVMTERGSSQLRADVVPLKQGDGVIFTVYQRPTQGRRSMRKVAMRHGVSKIRSGSRHAVGLIFHDAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3E7</accession>
    <name>A0A2S9H3E7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1007</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94386">
        <property type="protein sequence ID" value="PRC94386"/>
        <property type="gene ID" value="S2091_1007"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="283" mass="30891" checksum="96F551A854004DB6" modified="2018-07-18" version="1">MALNFLDMCSLPVYTAPYHACAEIDVKRFSNWRDLPMNALLTEGMNQFAVRFARTVLPKVMGSRLRVLPVGIRNLQQLDELGTGPFLVEGDVSQFGPTARVRITVRKMGAEATPVLMQAEVAAAVAGVVAVADGTPAHANSVPPLNWQVNDDPLFRLTSPFSQIDRYGFQVNPGCPLLEEHFPGFAVAPGSLVLSFVWEQTARRLGVRGKQLQIDDARFVRPVIPGVDYTCSLRDLAADGKPGRFRFVLSSANGDVHSQGIFHFEGMQDGLAVPQDEQTEVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3I0</accession>
    <name>A0A2S9H3I0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative transcription regulator containing HTH domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0542</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94539">
        <property type="protein sequence ID" value="PRC94539"/>
        <property type="gene ID" value="S2091_0542"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="122" mass="13806" checksum="97D1429F7ED12327" modified="2018-07-18" version="1">MDIKPIHTEDQYQSALREASKFFNAQPEPGSVDGDRFELLLMVIESYEAKHYPIAPPDPIDAIEFRIEQAGLTVKDLVPMIGQLNRVYEIMARKRILTLPMIRRLHAGLGIPAESLIAEPHT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3M3</accession>
    <name>A0A2S9H3M3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Pilus assembly protein, PilP</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0582</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94579">
        <property type="protein sequence ID" value="PRC94579"/>
        <property type="gene ID" value="S2091_0582"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007446">
        <property type="entry name" value="PilP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04351">
        <property type="entry name" value="PilP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="497" mass="53924" checksum="1EE67D0D97F811DE" modified="2018-07-18" version="1">MSVSTKTLYTRGALLKITWKKFYMFFIMTTCVTAFAQGNVIESISVIQPDSSSKTVLKIKLKNTIKNPPRVDMSTQSITLDFDATSSEMNSKSRDVAGADAVRSLSVSHSGDTSRVVFNLAPQRYCTLRREIDGIKITSISGVKSKDMSRPMNCAIRLEGDTVALTVDNFPSDESSWSPFGPPTAFEIRAKNIDARTLILVAAAQANLNVVVGDELKNKRLDISETSIEANQLITRAAHDQHLTTRLVNNILMIGSECRLAQNPSFPVLASDRDLVSMNFGNTSAFRVAHDIFPPMLNTIVDATAIDKVAPLTIRVRNATAKDQLIAVATVEGWLAHPLDSGGIRFVLNENLGKCGHHVTDQSSTGSVVANNASAPISGADGAPSFKAASSDSKSVSPERYRACSGTFPPSISCSPLEQYEIEELKPLGYTQSNSSSSRMIFIESVDGGIYWAKEGSYVGRNFGIIKNIGDTGVNIVERIQEVDGTWKDRPATLNFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3R5</accession>
    <name>A0A2S9H3R5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Major Facilitator Superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_0604</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94601">
        <property type="protein sequence ID" value="PRC94601"/>
        <property type="gene ID" value="S2091_0604"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004752">
        <property type="entry name" value="AmpG_permease/AT-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12778">
        <property type="entry name" value="PTHR12778"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="28"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="57"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="95"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="120"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="156"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="185"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="235"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="272"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="305"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="330"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="368"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="395"/>
            <end position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC94601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="428" mass="47177" checksum="52EEF3E57E0130C9" modified="2018-07-18" version="1">MQKVPSATNSLPPVEPTGWHQYLNQNMLICVALGFTSGLPLFILINLLTAWLKTEGVDLKAIGLFALVGFPYTWKFIWSPVMDRFSLPFLGRRRGWMFVTQLCLMAVIMAMGQLSPKTDLMLIVWLCGALAFLSASQDIVIDAYRREILSDNQQALGISLSVNAYKFSTLVPGSLALILSDHFNWDSVFIFTGLFMLPGIITTLLIKEPRLYGAPPKNIREAVVLPFQEFIQRKGVANALLILSFIFLYKLGDSMATALQTPFFMELGFTRTQIGVVAKSAGLWAGLAGGLFGAIWLMKIGINRGLWIFGVIQAVAILGFAMLTKMGLSVWMLGAVMVADTFAIGLGTAAFTAYIATTTDPRYTATQYALFSSLAVVPRTFFNAITGYIVLQTGWFGFFIICFLLTIPGMLLLPKIAPWNAKKNTQTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3S9</accession>
    <name>A0A2S9H3S9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0631</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94628">
        <property type="protein sequence ID" value="PRC94628"/>
        <property type="gene ID" value="S2091_0631"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015665083" evidence="1">
        <location>
            <begin position="25"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="203" mass="22928" checksum="4B1314A071DBFFC2" modified="2018-07-18" version="1">MKPRFTLFPLWLISSLFISFNANGGEGGGQTTSTPKAAMSIGAHDFDFFMGDWVIENRKLIKRLEGSDQWETFQARQHVQQLPGGIGNFDEFVAKTWKPDYVGMSLRVFNPETKLWSIYWLTNQNGGIDSKSGALMPPVVGKFENGVGIFEGADEFNGKPILVRYTWSQITNNSARWEQAFSPDAGKSWETNWIMQMTRASNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3X0</accession>
    <name>A0A2S9H3X0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0670</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94667">
        <property type="protein sequence ID" value="PRC94667"/>
        <property type="gene ID" value="S2091_0670"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="80"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="132"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="158"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="186" mass="20055" checksum="EFE5E157B6CFD618" modified="2018-07-18" version="1">MRLSLSEVQQEEMCHAYYDGAPGILVSGLVWIATALVCYLFGINQAVWTLLVGGSLIYPISAIVTKAVGRPAKTSKANALNQLAMASTIWLILCCAMAYGLFLFMPTLFFPAMMVTIGSRYLIFASIYGRSIFWVMGVSLIVAGNFVFFAAIPPVVAAGLGGLIEVLFAVFVFLKVSKPVHVACNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3Z7</accession>
    <name>A0A2S9H3Z7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Amidases related to nicotinamidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0684</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94681">
        <property type="protein sequence ID" value="PRC94681"/>
        <property type="gene ID" value="S2091_0684"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.850">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000868">
        <property type="entry name" value="Isochorismatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036380">
        <property type="entry name" value="Isochorismatase-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00857">
        <property type="entry name" value="Isochorismatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52499">
        <property type="entry name" value="SSF52499"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Isochorismatase" evidence="1">
        <location>
            <begin position="8"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="186" mass="20549" checksum="7C1C5454338A0FA0" modified="2018-07-18" version="1">MNQLPLDTVLVVIDVQQAFNDPSWGQRNNPAAEANIAALLAAWRKSQRPIIHIHHRSPRPESLFYPEHPGFKVKPEAEPQLDEPVLYKQVNSSFIGTDLEQRLRARGATTLVIVGITTDHCVSTTTRMAGNFGFVTYLVSDATATFDRVGPSGKYFSAEQMHETALASLHQEFATVVECASLLDCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H411</accession>
    <name>A0A2S9H411_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Malonate transporter, MadM subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0727</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94724">
        <property type="protein sequence ID" value="PRC94724"/>
        <property type="gene ID" value="S2091_0727"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044668">
        <property type="term" value="F:sodium:malonate symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004691">
        <property type="entry name" value="Mal/Na_symporter_MadM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018402">
        <property type="entry name" value="Mal/Na_symporter_MadM_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03818">
        <property type="entry name" value="MadM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00808">
        <property type="entry name" value="malonate_madM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="72"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="106"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="164"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="198"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="223"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="domain" description="MadM" evidence="2">
        <location>
            <begin position="5"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="254" mass="25797" checksum="FC6C9A39E84AE4C8" modified="2018-07-18" version="1">MLSTLEKAITSNGLVAAFALVGFIILISGFISRKLTFGRMHGSAIAILIGLALAYWGGIYSGGQKGLADVSLFAGIGLMGGAMMRDFAIVATAFEVRPDEARKAGLIGIVSLLLGTLVPFVVGAALAYYFGYRDAVSMTTIGAGAVTYIVGPVTGAAIGASSDVMALSIATGVVKAIMVMIGTPIVAKFLGLRTPRSAMVFGGLAGTVSGVSAGLAATDRRLVPYGALVATFHTGLGCFLGPSVLYFVTKAIMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H436</accession>
    <name>A0A2S9H436_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0741</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94738">
        <property type="protein sequence ID" value="PRC94738"/>
        <property type="gene ID" value="S2091_0741"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015716904" evidence="1">
        <location>
            <begin position="20"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="222" mass="24033" checksum="911A1CA4E6D50F91" modified="2018-07-18" version="1">MFKSILLCFGLLIVAAAHASSDDGKQGKDESAVIPPVQNIRSITPIFSQLLLAPYPSGFVTIFENVSDTQYIRESVPEGENENQWSQMITLNGAKDLATKAGVTSQMLVERIAGGFQRACPTSFLAIRVSDDKIGGNEAFAAIVSCGTSPTTDGKQSETALIAVIKGDKDFYTVQWAERATASKRPLTLDASKWVERYKTLTQVKLCHIVPGEQAPYPSCVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4A7</accession>
    <name>A0A2S9H4A7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0015</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94820">
        <property type="protein sequence ID" value="PRC94820"/>
        <property type="gene ID" value="S2091_0015"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="216" mass="24061" checksum="255BDCD357F8175B" modified="2018-07-18" version="1">MAHSKTTSILRKFFFGSVASTSEPLKIESVEINRPEGKRHYLKALPSRASSNKRPLVILLHGAGASAAQILGLKFPPSPLSMWLEIAEREQLVIVAPDGRKNNKLICWNDSCSEIAGNPKTDDTGFINAIIDKVIVEDTRMIWGGEAHALQVELIRIENGGHSEPSVMKRYPRWLTFLVGAQNADIEAAEEAWEFFKDKRSELLINQIAGNFHTID</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4F2</accession>
    <name>A0A2S9H4F2_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Lipoprotein signal peptidase</fullName>
            <ecNumber evidence="6">3.4.23.36</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Prolipoprotein signal peptidase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Signal peptidase II</fullName>
            <shortName evidence="6">SPase II</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">lspA</name>
        <name evidence="10" type="ORF">S2091_0060</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 7">This protein specifically catalyzes the removal of signal peptides from prolipoproteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>Release of signal peptides from bacterial membrane prolipoproteins. Hydrolyzes -Xaa-Yaa-Zaa-|-(S,diacylglyceryl)Cys-, in which Xaa is hydrophobic (preferably Leu), and Yaa (Ala or Ser) and Zaa (Gly or Ala) have small, neutral side chains.</text>
            <dbReference type="EC" id="3.4.23.36"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="6">Protein modification; lipoprotein biosynthesis (signal peptide cleavage).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 8">Belongs to the peptidase A8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.23.36" evidence="6"/>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94865">
        <property type="protein sequence ID" value="PRC94865"/>
        <property type="gene ID" value="S2091_0060"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00665"/>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00161">
        <property type="entry name" value="LspA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001872">
        <property type="entry name" value="Peptidase_A8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33695">
        <property type="entry name" value="PTHR33695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01252">
        <property type="entry name" value="Peptidase_A8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00781">
        <property type="entry name" value="LIPOSIGPTASE"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00077">
        <property type="entry name" value="lspA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00855">
        <property type="entry name" value="SPASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6 7" id="KW-0064">Aspartyl protease</keyword>
    <keyword evidence="2 6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 6 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 7" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="49"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="87"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="111"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="148"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="138"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC94865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="177" mass="19351" checksum="36385893B5EA3C1E" modified="2018-07-18" version="1">MATKKRASGSINTSTKSSSTPSHGLAPWLGLAAIVILLDQLSKITIAKLFAYGESLAVTNFFNLTLVYNKGAAFSFLASESGWQRHLFTVIGISAALYIIYLLKNHNGQRLFCWALALILGGALGNVIDRVMYGHVIDFLDFYYANSHFPAFNLADSAICLGAGLFILDELRRVKNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4N5</accession>
    <name>A0A2S9H4N5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="10">FtsX-like permease family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">S2091_0145</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94950">
        <property type="protein sequence ID" value="PRC94950"/>
        <property type="gene ID" value="S2091_0145"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025857">
        <property type="entry name" value="MacB_PCD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12704">
        <property type="entry name" value="MacB_PCD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="21"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="295"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="341"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="388"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="433"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="681"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="724"/>
            <end position="747"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="767"/>
            <end position="786"/>
        </location>
    </feature>
    <feature type="domain" description="MacB_PCD" evidence="9">
        <location>
            <begin position="20"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="8">
        <location>
            <begin position="326"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="domain" description="MacB_PCD" evidence="9">
        <location>
            <begin position="444"/>
            <end position="647"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF12704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC94950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="803" mass="87371" checksum="9F782033C4197809" modified="2018-07-18" version="1">MNLRDFRIGWRLLINEPVYSVMVVFGLTLGFAACFLLLGFVRYSFNYDAQVPDREHVYSVKQRINLISAPPIWTDGIQFPFSAIAKKSGLVIMTSFVHQIDALIVAENHTEIRSQKIELSAVEPDFPQLFGIQALEGDLQAALTKPDAIALTLSTAQKIFGETQILHKIVKIDEKSYQVAALLPDPPSNTMEPYLALVGTNTAAWPEADRASYVNNWDDGVGKLYLKLRVGATPAALENVLQDAVDRFGQLSKMGPDALRKRGGIKLQDMRIVSLADSYFDQDLNRHGAWGNKNVVIGLAVVAILILLLAAINYVNLAIVRTLRRQREIGLRKVLGASVHHIIGNFMAEALLVSVVATTLGILLAWLLLPLFSELMARKLDALFTSQNLMLCALFGLIVGLVTGIYPAWIALRVRAAESVAGRGNLETASGLWIRRVLTVMQFSVAMGFAGLTLAILWQTNYSRKSNPGFDPTQLVVIRMSIDLNDPIGVAFRDQLEHLPGVTGVAASLNPPANSSHKSANSVKSKTGQEVVLSSQDISPNFFDVVGVKPRAGRLFDPRLDQAANNHVILNWQAAQALGFASPEAAIGQMVSWGGDMTKQIIGIAPDIRHQSNRETAQAVVYLLSSRMTVLTVRSTGDFASLEKAVATIWTHSFPTDDMVMRRAQDVVAENYADDLRLAKLLAAASVLAIAIAAFGIYVLSAYSVQRRTREIVLRKLYGANGGAIAGLLAREFGILVAISALIGLPIAAVASEKYLAEFVERAPMGVWPLVGALALACVVAFFGILRHALLAIRMSPVVALRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4X3</accession>
    <name>A0A2S9H4X3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_0229</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95034">
        <property type="protein sequence ID" value="PRC95034"/>
        <property type="gene ID" value="S2091_0229"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032834">
        <property type="entry name" value="NatK_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010559">
        <property type="entry name" value="Sig_transdc_His_kin_internal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14501">
        <property type="entry name" value="HATPase_c_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06580">
        <property type="entry name" value="His_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="73"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="118"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="domain" description="His_kinase" evidence="2">
        <location>
            <begin position="160"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="domain" description="HATPase_c_5" evidence="3">
        <location>
            <begin position="260"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06580"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF14501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC95034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="350" mass="38441" checksum="DA312188E85BC041" modified="2018-07-18" version="1">MHPILSDLRKLISYLVAWLLVGMLIAKFLALTGLASWSTALLFSLPVVVIYGFVASSAYYVCRSLPMTGRRLIPTVVLFCGASLFSGGIWLTLCLGWNNLATSLDWWSITFTPNSVSLLFSAGCGCYLISLLLHDGLIALDNIRNAELSAAKSRVLAREAELHMLRAQINPHFLFNSLNSISALTSIDTVAARAMTIALAQFFRQSLALSEQTTIALAKEIALCDSFLEVEKIRFGSKLQSEFNIEDQAQIALLPPMLLQPLIENAIKHGIRDLSDGGVIRLTGLVRDNWLHISIENPCDETPSSTIGNGLGLKNIKQRLMNVYGNQASIQWNKTDTSFSVEITLPLQLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H541</accession>
    <name>A0A2S9H541_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Prepilin-type N-terminal cleavage/methylation domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0256</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95061">
        <property type="protein sequence ID" value="PRC95061"/>
        <property type="gene ID" value="S2091_0256"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC95061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="140" mass="14515" checksum="6C4C40B3D694E59A" modified="2018-07-18" version="1">MKASQQGFTLIELMIVIAIIGILAAVAVPQYQNYMNKAKFTEVISATAPHKLGVVLCIADLGINTGCDSGKNGIPNEITSATTGHVGSLKVKDGLITATAATKLGQTEPPTYILESKVEEDGVAAWVVKGTCASAVPKLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H546</accession>
    <name>A0A2S9H546_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0305</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95110">
        <property type="protein sequence ID" value="PRC95110"/>
        <property type="gene ID" value="S2091_0305"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="6"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC95110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="311" mass="35064" checksum="90AA008D268CC385" modified="2018-07-18" version="1">MFERLPPTQTLRAFEAAARLENFTRAGEELNITHSAISHQIRALEQSTGRKLFQRQGRQMVLTGAGKLLSEQVRLALEDLDRALRLTRQESKRQTQTLRLATPPSFAGVWLVPRLYEFHAQHPQLEISLRTTHELNELDFDEADIAVWYGRKTSSELEYELLLDEVTFPVCSPEFLAKHPHLTPATLAASPNTLPPLPLLRYAHHSGWEVWFKAAGIRGREPQSGPLYDDPIHLLEAAAAHQGIALARSCLVGSYLANGRLVRLFDETSPYNINAPARGAYFAVWPRNANKTEAIALLRSWLHSILDKPDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H550</accession>
    <name>A0A2S9H550_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Neisseria PilC beta-propeller domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_0248</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PilY1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95053">
        <property type="protein sequence ID" value="PRC95053"/>
        <property type="gene ID" value="S2091_0248"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009289">
        <property type="term" value="C:pilus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008707">
        <property type="entry name" value="PilC_beta_prop_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_supfam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05567">
        <property type="entry name" value="Neisseria_PilC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="SSF50998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0281">Fimbrium</keyword>
    <keyword evidence="2" id="KW-1029">Fimbrium biogenesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015587311" evidence="4">
        <location>
            <begin position="21"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="domain" description="Neisseria_PilC" evidence="5">
        <location>
            <begin position="176"/>
            <end position="505"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF05567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC95053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="695" mass="74707" checksum="89C4A91131EE1AB2" modified="2018-07-18" version="1">MKFKNLLSSIALLTPLFTSAATPEVDLAKIPLCGIGTISGVTPSSPKITDNPFAYQSGFDASTWSGKLRKLTIKLDDDGGVVITTPNDPVWDAGTLLNTQITRSIFTINSANKTMVSFEFHNLAPDVQALFNLTPDTTAVDNLGVQRVSYLRGVREKEHATTKLDKPLFRVRNSVLGDIINSSPVYVAAPARNIIGSGYQAFYDQNKSRSRVVYVGANDGMLHAFHADTGTELFAYIPSPLLKKLPLLTDPNYAHVAFMDGNITVSEAQLSGTWKTVLAAGMGAGHKGVFALDVTNPGDFKAGLGELFEFTDDDDSDIGYITSAPLIAKIRTSKNNNGSFNYKNYLVTASGYNANTTDGYGDGYLFLLSLDKDKNTAWQEKVNYYKIKAPNTNEFIANALAAPGLALHSDGSAIYAYAGDLKGNLWRFDFTGGAGSKKEATAVFTAKDHFGKPQSITAQPVIAFAPGGGYLILFGTGKYVENADTTPANFTPNSFYAVRDSTDNKDITTGGRNDLAKRTLAVASINGVSGYTITGDDFSYGTASGTKKGWYVDFLKAEDTGELSITPALLVSGKLFFNTLIPGANICEPGFGATYTLDILTGKASQAERITGLKSQIGLLSIPVLIFTDNLTDDRDALGRRNNTTNYSVLNFGTGGVEGSSEVSETGNFTAKAGRLSWREIQNWQELQEAILNKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5A9</accession>
    <name>A0A2S9H5A9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">CHASE3 domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_0370</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95175">
        <property type="protein sequence ID" value="PRC95175"/>
        <property type="gene ID" value="S2091_0370"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004888">
        <property type="term" value="F:transmembrane signaling receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007891">
        <property type="entry name" value="CHASE3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004090">
        <property type="entry name" value="Chemotax_Me-accpt_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004089">
        <property type="entry name" value="MCPsignal_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05227">
        <property type="entry name" value="CHASE3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00015">
        <property type="entry name" value="MCPsignal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00260">
        <property type="entry name" value="CHEMTRNSDUCR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00283">
        <property type="entry name" value="MA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50111">
        <property type="entry name" value="CHEMOTAXIS_TRANSDUC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0807">Transducer</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="186"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="domain" description="Methyl-accepting transducer" evidence="4">
        <location>
            <begin position="217"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="152"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC95175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="489" mass="52464" checksum="B1BA8952AAA2E18B" modified="2018-07-18" version="1">MNRNWTFGRKVAFGFTVSSIFLIIVGIVGYWSTYALIDTSYSVTHTHKVIEQISTYLSNMKDAETGQRGYLLTGDLAYLEPYTTAVAAAPKLLNELRSLTVDSSNQQRLVDQMESLTASKFDELGRTIMLKKAGRSDDVLKLVLTNEGKIYMDNLRKVSEQLSQEERNLLEKRAAEAESTVNTAKVTILVGTLICLVFVVITAFMITRSLATQLGAAVGHVQSSSTELQAAATQQASGAKEQASAMNEISTTISELGVTSRQIAESAQRVAQIAEQTAGAARAGEGTVDKGQDAISGVRRQIDQVVNHMLDLGRKSQEIGAVLDIVSELAEQTNILAINATIEATGAGEAGKRFSVVAEEIRKLADRVANSTKGIRTQVEDVRSAVNTTVMATESGAKAVDAGARQFTEVAVAFKQIASLVGTTTEAAREIELSTKQQATAAEQVRIAVTDVAQATQETETSSSQTLQTATQLAGLALDLRRLIQPQAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5D5</accession>
    <name>A0A2S9H5D5_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">Cell division protein FtsZ</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ftsZ</name>
        <name evidence="9" type="ORF">S2091_0394</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4 5">Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="4">Assembles at midcell at the inner surface of the cytoplasmic membrane.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4 5">Belongs to the FtsZ family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95199">
        <property type="protein sequence ID" value="PRC95199"/>
        <property type="gene ID" value="S2091_0394"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032153">
        <property type="term" value="C:cell division site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000917">
        <property type="term" value="P:division septum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043093">
        <property type="term" value="P:FtsZ-dependent cytokinesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051258">
        <property type="term" value="P:protein polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02201">
        <property type="entry name" value="FtsZ_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1440">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00909">
        <property type="entry name" value="FtsZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000158">
        <property type="entry name" value="Cell_div_FtsZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020805">
        <property type="entry name" value="Cell_div_FtsZ_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045061">
        <property type="entry name" value="FtsZ/CetZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024757">
        <property type="entry name" value="FtsZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008280">
        <property type="entry name" value="Tub_FtsZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037103">
        <property type="entry name" value="Tubulin/FtsZ-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018316">
        <property type="entry name" value="Tubulin/FtsZ_2-layer-sand-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036525">
        <property type="entry name" value="Tubulin/FtsZ_GTPase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003008">
        <property type="entry name" value="Tubulin_FtsZ_GTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30314">
        <property type="entry name" value="PTHR30314"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12327">
        <property type="entry name" value="FtsZ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00091">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00423">
        <property type="entry name" value="CELLDVISFTSZ"/>
    </dbReference>
    <dbReference type="SMART" id="SM00864">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00865">
        <property type="entry name" value="Tubulin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52490">
        <property type="entry name" value="SSF52490"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55307">
        <property type="entry name" value="SSF55307"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00065">
        <property type="entry name" value="ftsZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01135">
        <property type="entry name" value="FTSZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4 5 9" id="KW-0132">Cell division</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 4 5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2 4 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0717">Septation</keyword>
    <feature type="domain" description="Tubulin" evidence="7">
        <location>
            <begin position="14"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="domain" description="Tubulin_C" evidence="8">
        <location>
            <begin position="204"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="355"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="22"/>
            <end position="26"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="106"/>
            <end position="108"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="137"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="184"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC95199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="407" mass="42464" checksum="7AB8A852E2829107" modified="2018-07-18" version="1">MEFEMIDNATQGTIIKVVGVGGAGGNAVQHMINKGVSGVEFIAANTDAQALAHSNAHNVIQIGETGLGAGMKPEVGRQLAEESKARIEDALRGAHMVFIAAGMGGGTGTGAAPIVAKIAKEQGALTVAVVSKPFSYEGQKCMDIADAGLEALSEHVDSLIIILNEKLEEIYEDGTMLEWMQHADDVLNNAVAGIAEIINVPGHINVDFNDVKTIMSEQGKAMMGTATASGIDRARIAAEQAVASPLLDGIDLSGARGVLVNVTASRSLKGKEIREVMAAVRAFAAPDASIAQGIAYDDNMGDNIRVTVVATGLGRSKKSIQLVQQAPMLRTGTNNEPVMSGNINVGHVAHGAQGGTTQTTSGSMHGFDSPKGPAVWRRESASETVRALEKNGMETYDIPAFLRKQAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5E9</accession>
    <name>A0A2S9H5E9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Thiamine pyrophosphate-requiring enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_0410</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the TPP enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95215">
        <property type="protein sequence ID" value="PRC95215"/>
        <property type="gene ID" value="S2091_0410"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044281">
        <property type="term" value="P:small molecule metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012000">
        <property type="entry name" value="Thiamin_PyroP_enz_cen_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012001">
        <property type="entry name" value="Thiamin_PyroP_enz_TPP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045229">
        <property type="entry name" value="TPP_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011766">
        <property type="entry name" value="TPP_enzyme-bd_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18968">
        <property type="entry name" value="PTHR18968"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02775">
        <property type="entry name" value="TPP_enzyme_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00205">
        <property type="entry name" value="TPP_enzyme_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02776">
        <property type="entry name" value="TPP_enzyme_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="SSF52467"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0786">Thiamine pyrophosphate</keyword>
    <feature type="domain" description="TPP_enzyme_N" evidence="5">
        <location>
            <begin position="17"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="domain" description="TPP_enzyme_M" evidence="3">
        <location>
            <begin position="215"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="domain" description="TPP_enzyme_C" evidence="4">
        <location>
            <begin position="412"/>
            <end position="561"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU362132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC95215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="586" mass="63674" checksum="51FC4A199036A653" modified="2018-07-18" version="1">MSSPTNALNSTSSASRSGGQLIVDALQIHGVDTIFGVPGESYLPVLDALHEHKNNESNIKNPIRFIINRQEGGSAFMAEAYGKLTGKPGICFVTRGPGATNASIGVHTAYQDSTPMILFIGQVGNDFVEREAFQEIDYRRMYGQMAKWVAQIDRADRVHEYVARAFQVATSGRPGPVVLALPEDMLSQLVEVDKIPQVRHYQTVQAAPSNAQMNELSSRLAAAKRPIVILGGGGWNKAACDNLQRFAEQQKLPISCAFRFQDLFDNQHPNYAGDVGIGINPKLAERIKQADLVIAIGPRLGEMTTSGYSILEAPVPKQSLIHIHADALELGRVYQADMLINSGMPQIAEALAALPTLDSSAWQASVETARADYIANQAPSPIFQNNTHPLNLWQVVQEMSAQVPADTIITNGAGNHTTWAHRYYRYGAMRTQLAPTSGAMGYSVPSGIAAKITHPERTVITFAGDGEFMMNGQELATAVQYRAGVVIILFNNGMFGTIRMHQEREFPNRVVGTELHNPDFAALARAYGGSGEVVTHTEEFGPALQRALAFSRENSLPALIELRYDGNLITPGATLEAIRQVALGNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5H9</accession>
    <name>A0A2S9H5H9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ABC-type multidrug transport system ATPase component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_0439</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95244">
        <property type="protein sequence ID" value="PRC95244"/>
        <property type="gene ID" value="S2091_0439"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-1278">Translocase</keyword>
    <feature type="domain" description="ABC transporter" evidence="7">
        <location>
            <begin position="6"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="38"/>
            <end position="45"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC95244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="306" mass="34080" checksum="AD7A3D158DD8B580" modified="2018-07-18" version="1">MAALAIEATGLQKRFGDVHAVRGLDLQVKSGEVFGLLGPNGAGKTTSLEMLEGLVQPDAGEIRILGLDWRKQGAAIRNRIGVQFQSTQLDDKVKVREALEMFGCYYAKSRKPADLLRLLQLEDKAEVYQSKLSGGQRQRLALGLALVNEPELVFLDEPTTGLDPQARQGLWDLVRQLKSEGRTVLLTTHYMDEAEALCDRIGIMDHGQILQLGTPRELIASLNQPSYAEIEFQGSVPNVQPFAERLGMHVEVKAQHWAVPLTDPKRDLQQLLSCVEALDLPMQQLHVRRASLEDVFLQRTGRSLRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5I4</accession>
    <name>A0A2S9H5I4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">GGDEF: diguanylate cyclase (GGDEF) domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_0437</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95242">
        <property type="protein sequence ID" value="PRC95242"/>
        <property type="gene ID" value="S2091_0437"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01948">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029150">
        <property type="entry name" value="dCache_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001633">
        <property type="entry name" value="EAL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035919">
        <property type="entry name" value="EAL_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029151">
        <property type="entry name" value="Sensor-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14827">
        <property type="entry name" value="dCache_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00563">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00052">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103190">
        <property type="entry name" value="SSF103190"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141868">
        <property type="entry name" value="SSF141868"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50883">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="278"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="4">
        <location>
            <begin position="300"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="5">
        <location>
            <begin position="420"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="domain" description="EAL" evidence="3">
        <location>
            <begin position="560"/>
            <end position="813"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="387"/>
            <end position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC95242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="825" mass="91390" checksum="705A02D6F85D2D3D" modified="2018-07-18" version="1">MHFRTLESRIVTLFLALILVGQAVSFCVIRNGIIDNEQAAIRDQLALGVPLFNRLLEQKAQTLTSSARAVSKDYGFRQAIASNDKETIESVLTNAGQRINASLTLFMGLDRQIKATTTKQQPGSLEQSILLLIDQAEEKDGAVGMSIFENRPYQVLVVPVRAPVTIGWIAMAFPLDLKLASDMRDLSSLDVSFMVSDKDGGWQADVSTLSQADASSVASLLQGLSGKVAALMPLRIAKSDYSVRILPLVQSVAGGQGAIVVLQRSIDEAIAPYRQLQVSLIMITGLVTFVAFILSFFAARRIASPLRDLTAIAKRLGDGDYQTQIEIKGDDEIRKLSMAFESMRGGIAKHESQIRRLAYWDTLTNLPNRAQFTVMLDEAIKNSAQLVNEPANQQTNHEENKRTNRRTNRHIHKQTNQQTKTGHILMMDLDRFKNVNDVLGHHFGDELLRQVAHRLTKTVGIHYPVARLGGDEFAVLLPMTDVSEAKEIAARVLKSLELPISLEDQTVDLGAGLGIAGFPLHGTDAESLMSRAEVAMYAAKINSNEAVLYDPALDKASQQNLSLLSELRRALECNEFKMFVQPKLRIDTGEFIGLEALVRWEHPEKGMIYPDQFIPFSEQTGFIRALTRWMLEQSAMLCRDLTAYGINAKISVNLSTRDLLDQNLPAKFSAMLARYAVSASSFCLEITESSIMDDPVRALLTLDGLHAMGVDLSIDDFGTGYSSLAYLKRLPVDELKIDQSFVMNMESDIEDAKIVRSTIDLGHNMGLRVVAEGIESEAVWWLLAKMGCDQGQGYFMSRPMPAAQLIGWIAQWVPPRMKRDTVSSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5P4</accession>
    <name>A0A2S9H5P4_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 6">Phosphate-binding protein PstS</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">S2091_0456</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 6">Part of the ABC transporter complex PstSACB involved in phosphate import.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 6">The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the PstS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95261">
        <property type="protein sequence ID" value="PRC95261"/>
        <property type="gene ID" value="S2091_0456"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042301">
        <property type="term" value="F:phosphate ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035435">
        <property type="term" value="P:phosphate ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005673">
        <property type="entry name" value="ABC_phos-bd_PstS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024370">
        <property type="entry name" value="PBP_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12849">
        <property type="entry name" value="PBP_like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002756">
        <property type="entry name" value="PstS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00975">
        <property type="entry name" value="3a0107s03"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0592">Phosphate transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015492445" description="Phosphate-binding protein PstS" evidence="8">
        <location>
            <begin position="23"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="domain" description="PBP_domain" evidence="9">
        <location>
            <begin position="23"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="region of interest" description="Phosphate binding" evidence="7">
        <location>
            <begin position="30"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Phosphate binding" evidence="7">
        <location>
            <begin position="160"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="59"/>
        </location>
        <ligand>
            <name>phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="77"/>
        </location>
        <ligand>
            <name>phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR002756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR002756-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF12849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC95261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="348" mass="37977" checksum="49FD2589E67FA246" modified="2018-07-18" version="1">MFSLKKIILGLLVISIQHVSLADPINGAGSSAAQPLYTKWATAYAQKTGLDVAYEAIGSSAGIKKIKGKLIDFGASDVALTADDLQQSQMIQFPSAISGVVPVVNLIGIKPGELKLNGETLAGIFSHQITKWNDAAIAALNPGLTLPKAAIIVVTRVDGSGTTYNFSDYLSRVSPDWKTRFGCNFLIKWPTETQQVKGSSGIVALIKQTPNTISYIDYNYVVQEKLSYVQLQNADGNFVTPKPANFESALNHSTWKTQANFNEMLTDKAGPTSWPITMGTFIIMPKVTQNNSKTIAALKFFSWGFMQGDHYVNSLDFVHLPDSIQAKIFKQMTSITDTFGNHLNWSPM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5Q3</accession>
    <name>A0A2S9H5Q3_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Cell division coordinator CpoB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">cpoB</name>
        <name evidence="5" type="ORF">S2091_0466</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the CpoB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95271">
        <property type="protein sequence ID" value="PRC95271"/>
        <property type="gene ID" value="S2091_0466"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030288">
        <property type="term" value="C:outer membrane-bounded periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043093">
        <property type="term" value="P:FtsZ-dependent cytokinesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070206">
        <property type="term" value="P:protein trimerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02066">
        <property type="entry name" value="CpoB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039565">
        <property type="entry name" value="BamD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034706">
        <property type="entry name" value="CpoB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014162">
        <property type="entry name" value="CpoB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032519">
        <property type="entry name" value="YbgF_tri"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16331">
        <property type="entry name" value="TolA_bind_tri"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13525">
        <property type="entry name" value="YfiO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02795">
        <property type="entry name" value="tol_pal_ybgF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1" id="KW-0132">Cell division</keyword>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0574">Periplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0802">TPR repeat</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015788977" description="Cell division coordinator CpoB" evidence="1">
        <location>
            <begin position="24"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="domain" description="TolA_bind_tri" evidence="4">
        <location>
            <begin position="56"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="domain" description="YfiO" evidence="3">
        <location>
            <begin position="128"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="166"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="62"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF16331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC95271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="250" mass="27985" checksum="D1DE2656B36EFCFE" modified="2018-07-18" version="1" precursor="true">MKRFFLSLLTVLSIGILTTPAHAGLFDDDEARKAILDLRTKLDTVSSKLDDQITNKADKTVVLDQLNQLDSLRQEIAKLRGQVEVLSNDVSDSQRRQKDFYVDLDNRLRKLEPQKLLVDGKEAQIDPNEQKSYDTALAVFQSGDYSGAANALNSFIQMYTRSAYVPNAQYSLGIAYYAQKDYRNAIATFQSLVKASPDFSRAPDAMLTIATCYSEQKDKTAARKVLQNLRTQYPDSAAAKTAIDRLNALK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSC3</accession>
    <name>A0A2S9GSC3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4681</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000044">
        <property type="protein sequence ID" value="PRC90613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90613">
        <property type="protein sequence ID" value="PRC90613"/>
        <property type="gene ID" value="S2091_4681"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC90613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="136" mass="15151" checksum="07945A98FEF9506C" modified="2018-07-18" version="1">MIGGAEIGTAILPGVGTVVGGAVGFGVGWWLADKAYDAINSDPLQSTKQARKESHDAYKAFQRQGYERDPNDPCQELRNKIAFHEQMIAARTAHDMSFPNPGWPDGKRHADVNDFDSENVTRWKKELEDCEKSCKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSH7</accession>
    <name>A0A2S9GSH7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_4656</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000041">
        <property type="protein sequence ID" value="PRC90648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90648">
        <property type="protein sequence ID" value="PRC90648"/>
        <property type="gene ID" value="S2091_4656"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="14"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC90648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="305" mass="33896" checksum="05A6C49FCD5EA40F" modified="2018-07-18" version="1">MFISFGKPFTMPSLNYKHLHYFWSVAKHGSIIEASRHLHITPQTISAQLNLFEETHGEKLFLKSGRNLELSESGRMVLNYANEIFSLGQELEEVLQLHPSSRSLFLRVGISDAVPKTIAHKLLEPALQLSQPLRINCQEGKIGDLLAELAAHKLDVVISDAPMPAMLNVRAYNHFLLQSDISFFASPTLIAQHPQPFPFCLHEAPLLLQGEDTAVRLKLLQWLNAAGVNPIIAGEFDDAALMMAFGKAGVGFFSAPSSIAELVEQQYQVNRVGNCPEVLDHFYAISIERKISHPAVLAIQQGNRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSH8</accession>
    <name>A0A2S9GSH8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Acetyl-CoA acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_4624</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the thiolase-like superfamily. Thiolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000039">
        <property type="protein sequence ID" value="PRC90674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90674">
        <property type="protein sequence ID" value="PRC90674"/>
        <property type="gene ID" value="S2091_4624"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002155">
        <property type="entry name" value="Thiolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020615">
        <property type="entry name" value="Thiolase_acyl_enz_int_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020617">
        <property type="entry name" value="Thiolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020613">
        <property type="entry name" value="Thiolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020616">
        <property type="entry name" value="Thiolase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02803">
        <property type="entry name" value="Thiolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00108">
        <property type="entry name" value="Thiolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000429">
        <property type="entry name" value="Ac-CoA_Ac_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00098">
        <property type="entry name" value="THIOLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00737">
        <property type="entry name" value="THIOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thiolase_N" evidence="4">
        <location>
            <begin position="5"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="domain" description="Thiolase_C" evidence="5">
        <location>
            <begin position="271"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC90674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="394" mass="41502" checksum="C1C7C676D653633B" modified="2018-07-18" version="1">MNTKVIVAGVGMIPFTKPGTNAPYDEMGSEAARMALADAGLSYEDMQQAYVGYVYGDSTSGQKSLYKVGMTGIPVINVNNNCSTGSTALFLARQAIASGVVDCVLVLGFEQMSPGALNSVFQDRPSPFDPFDRVTAELVGMPQLPLALRYFGGAGLSHMQKFGTPIDSFAKIRAKASRHAVNNPLAVFKQVVTAEDVLNSTMIWPGVMTKLMACPPTCGAAAAVLVSEKYAKAKGLNAGVYIAAQAMTTDKPSTFESGDMMRLVGYEMSKEAAQKVYEESGIGPDELDVVELHDCFAHNELITYEALGLCPEGGATKFINDGDNTYGGKVVTNPSGGLLSKGHPLGATGLAQCFELTHQLRGTAGARQVDNAKVGLQHNLGLGGACVVTMYRAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSK7</accession>
    <name>A0A2S9GSK7_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Tryptophan--tRNA ligase</fullName>
            <ecNumber evidence="2">6.1.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_4583</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.2" evidence="2"/>
    <dbReference type="EMBL" id="PUGF01000038">
        <property type="protein sequence ID" value="PRC90690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90690">
        <property type="protein sequence ID" value="PRC90690"/>
        <property type="gene ID" value="S2091_4583"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004830">
        <property type="term" value="F:tryptophan-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006436">
        <property type="term" value="P:tryptophanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00806">
        <property type="entry name" value="TrpRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002305">
        <property type="entry name" value="aa-tRNA-synth_Ic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002306">
        <property type="entry name" value="Trp-tRNA-ligase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00579">
        <property type="entry name" value="tRNA-synt_1b"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01039">
        <property type="entry name" value="TRNASYNTHTRP"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00233">
        <property type="entry name" value="trpS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 8 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC90690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="400" mass="45382" checksum="19B86657D4D1D98D" modified="2018-07-18" version="1">MYPERVVSGMRPTGAMHLGHYHGALKNWIKMQAELPCLFFVADWHALTTHYDDPSSLEKSTWDMLIDWLAAGVDPSQATLFIQSKVPEHAELHLLLSMATPLGWLERVPTYKDQQEKLQDRDLSTYGFLGYPLLQAADVLIYRASQVPVGDDQVPHVEMMREIARRFNHIYGKEKGFEKNAVEAVKKLGSKRAKLYTELRAEFQEQGLVASLDQAHALLNEAQNLSMIDRERLFGYLEGSRKLILVEPQVKLTTSSRLPGLDGQKMSKSYGNAIALREDKDSLTLKIRTMVTDPARVRRTDIGNPEKCPVWQLHQVYSDEDTKEWVQKGCRSAGIGCLDCKQPVIEAIIKEQEPMHERAQQYLDEPSLVRAIAADGCDKARKLAQETMRDVREAMGISYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSN0</accession>
    <name>A0A2S9GSN0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glutathione S-transferase, C-terminal domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4558</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000037">
        <property type="protein sequence ID" value="PRC90732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90732">
        <property type="protein sequence ID" value="PRC90732"/>
        <property type="gene ID" value="S2091_4558"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14497">
        <property type="entry name" value="GST_C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="SSF47616"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GST C-terminal" evidence="1">
        <location>
            <begin position="92"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="242" mass="27686" checksum="4D4045036175EA5D" modified="2018-07-18" version="1">MRFELYYWPTIQGRGEYIRLALEQAGAKYIDVARRAESSGMGVQAMVDLMNNNEAPYPPFAPPFLKAGELIIAQTANILLFLGPQLGLVGVDESSRIWAHQLQLTVSDFVTEVHDTHHPIAGGLYYKDQKPEAKRCAADFIETRLPKFLGYFEHVIECNPFGDQFMIGAELSYVDLSIFQIIEGLRYAFPNAMKKTEFSYPLLLDLHHRVALQPRIARYLKSTRRVPFSKQGIFRHYNELDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSU9</accession>
    <name>A0A2S9GSU9_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Flagellar FliJ protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">S2091_4529</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the FliJ family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000036">
        <property type="protein sequence ID" value="PRC90781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90781">
        <property type="protein sequence ID" value="PRC90781"/>
        <property type="gene ID" value="S2091_4529"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009288">
        <property type="term" value="C:bacterial-type flagellum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003774">
        <property type="term" value="F:cytoskeletal motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044781">
        <property type="term" value="P:bacterial-type flagellum organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071973">
        <property type="term" value="P:bacterial-type flagellum-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018006">
        <property type="entry name" value="Flag_FliJ_proteobac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012823">
        <property type="entry name" value="Flagell_FliJ"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02050">
        <property type="entry name" value="FliJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF019404">
        <property type="entry name" value="FliJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01004">
        <property type="entry name" value="FLGFLIJ"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02473">
        <property type="entry name" value="flagell_FliJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1005">Bacterial flagellum biogenesis</keyword>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="12" id="KW-0966">Cell projection</keyword>
    <keyword evidence="7" id="KW-0145">Chemotaxis</keyword>
    <keyword evidence="12" id="KW-0969">Cilium</keyword>
    <keyword evidence="12" id="KW-0282">Flagellum</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="119"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PRC90781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="146" mass="17149" checksum="14FA0F9DD80C6BF1" modified="2018-07-18" version="1">MAQSSPLTTLIELAERMTDEAAAKLGLAIRSCDELEQKLNLLKKYRDDYSLKMQAELKVGRNMQHIRNFQLFLGKIDDAIKGQQLLVISAQQRVLVARQNWQDQERKRMSYSTLEVRAEKVQQKKEARRDQRQNDEHGTRQAFFKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSW9</accession>
    <name>A0A2S9GSW9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Outer membrane protein family (DUF1597)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_4464</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000035">
        <property type="protein sequence ID" value="PRC90801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90801">
        <property type="protein sequence ID" value="PRC90801"/>
        <property type="gene ID" value="S2091_4464"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011486">
        <property type="entry name" value="BBP2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07642">
        <property type="entry name" value="BBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015705264" evidence="2">
        <location>
            <begin position="30"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="77"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC90801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="553" mass="60817" checksum="6D1F825C8B953FB3" modified="2018-07-18" version="1">MSSCNSRVNGRLLMALAFAGVVGTPIAYAGDTGSSEAAVKPSAACDPYKDFSCLDSYLGTGVWERMANYYSLEHGHDGAPVDPKAPPSRRDDQTPAAQTAPPMPFTEWPYGGTSPLGASTPNATDSPLMVGLANTSFGKWMADNNIQTYGWIDVGANLSTSKVHGGNAPAAYDYNPNALDLNQIVEYFERVPDMVQKDHNDWGFRVSAIYGSDYRYTTSYGLGSYQLLNKNAANGWDLPMLYADWYTPFVGNGLNIRVGRYISVPDIEAQLAPNNYMYSHSMTYTFDNYTNEGILASLQANKNLILQAGITIGTEATFNHAWQTEPNTNPNALYPNSTFKVDPGARPAGTLCARYNSDDGKSNVNACANGINNGEWGYNNLQWYGVTAYHAFNDHWHLSWELYEEHQKDVPNLNNAYVQTNIVNTGTGTPFSPNVMPFNAPGMAFCSNANVLTCTAYSIGSTAYLNYSPDPLNNFSIRPEIYKDEQGQRTGVATTYKNLAIGWQHWLSPQIELRPEIAYYHADLPAFNGNSNRGISPDKKSETILSGDIIFHW</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GT15</accession>
    <name>A0A2S9GT15_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4440</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000034">
        <property type="protein sequence ID" value="PRC90859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90859">
        <property type="protein sequence ID" value="PRC90859"/>
        <property type="gene ID" value="S2091_4440"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="161" mass="17969" checksum="4D96F3D86824805F" modified="2018-07-18" version="1">MVKISSDDVTGTTKAFVFVPLALLVLIIVATSIDVFRNGGSPIIPFALSLILILIIWSFRKFTWSLADEVYDDGDKLLVKRRKDEQEILLSDIENLFDRSFSRPPKITLDLLVDGVFGSSISFVPINSGSPLEFRNGIATDLSLRINKAKADYYKNIGEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GT32</accession>
    <name>A0A2S9GT32_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4370</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000033">
        <property type="protein sequence ID" value="PRC90877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90877">
        <property type="protein sequence ID" value="PRC90877"/>
        <property type="gene ID" value="S2091_4370"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="25"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="56"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="93"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="124"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="167" mass="19082" checksum="87615AC08454DD50" modified="2018-07-18" version="1">MNETSLNSKPSNIISEQVPKKPKSVLLVQILASVFLLAFLMGIVRMSIRMINHESLAQFGMSVIVRFGVQLAIIFILVVLLISLHKRSKIGRILGLVFIGATMLPEIMPMIFINPSAISERYEFVYFATILVFLLPLAYWMYSFFFSVNSRQYFKLCPAEREINIEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GT54</accession>
    <name>A0A2S9GT54_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5 7">Histidine ammonia-lyase</fullName>
            <shortName evidence="5">Histidase</shortName>
            <ecNumber evidence="3 5 7">4.3.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">hutH</name>
        <name evidence="9" type="ORF">S2091_4390</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>L-histidine = NH4(+) + trans-urocanate</text>
            <dbReference type="Rhea" id="RHEA:21232"/>
            <dbReference type="ChEBI" id="CHEBI:17771"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:57595"/>
            <dbReference type="EC" id="4.3.1.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 5 7">Amino-acid degradation; L-histidine degradation into L-glutamate; N-formimidoyl-L-glutamate from L-histidine: step 1/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5 8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="5">Contains an active site 4-methylidene-imidazol-5-one (MIO), which is formed autocatalytically by cyclization and dehydration of residues Ala-Ser-Gly.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the PAL/histidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.3.1.3" evidence="3 5 7"/>
    <dbReference type="EMBL" id="PUGF01000033">
        <property type="protein sequence ID" value="PRC90897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90897">
        <property type="protein sequence ID" value="PRC90897"/>
        <property type="gene ID" value="S2091_4390"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00379">
        <property type="reaction ID" value="UER00549"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004397">
        <property type="term" value="F:histidine ammonia-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019556">
        <property type="term" value="P:histidine catabolic process to glutamate and formamide"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019557">
        <property type="term" value="P:histidine catabolic process to glutamate and formate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00332">
        <property type="entry name" value="PAL-HAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.275.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00229">
        <property type="entry name" value="His_ammonia_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001106">
        <property type="entry name" value="Aromatic_Lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024083">
        <property type="entry name" value="Fumarase/histidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005921">
        <property type="entry name" value="HutH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008948">
        <property type="entry name" value="L-Aspartase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022313">
        <property type="entry name" value="Phe/His_NH3-lyase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10362">
        <property type="entry name" value="PTHR10362"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00221">
        <property type="entry name" value="Lyase_aromatic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48557">
        <property type="entry name" value="SSF48557"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01225">
        <property type="entry name" value="hutH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00488">
        <property type="entry name" value="PAL_HISTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5 7" id="KW-0369">Histidine metabolism</keyword>
    <keyword evidence="5 6 9" id="KW-0456">Lyase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="modified residue" description="2,3-didehydroalanine (Ser)" evidence="5">
        <location>
            <position position="145"/>
        </location>
    </feature>
    <feature type="cross-link" description="5-imidazolinone (Ala-Gly)" evidence="5">
        <location>
            <begin position="144"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC90897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="513" mass="53778" checksum="CAE8CCA4EB931CD8" modified="2018-07-18" version="1">MMSTFTIQPGQFSLADLRQVWQTRSSLALAPQAYVAIDASAAAIANIVARGDAAYGINTGFGKLAKTRIPDDQLELLQRNLILSHSVGTGELIADNVVRLILLMKIGSLSRGVSGIRRSVIDAMIALFNAGITPCIPVKGSVGASGDLSPLSHMTLALLGEGDVRVAGEIMPAMDALKQAGITPVVLAAKEGLALINGTQVSTALALNGLFLAERLLEAATVAGAMSIDAAKGSDAPFDARIHAVRGQPGQIASAKLYRELLEGSAIRKSHLVDDERVQDPYCLRCQPQVMGACLDLINNVARTLLIEANAVTDNPLVFVETEEVISGGNFHAEPVAFAADTLALAIAEIGSISERRIALLIDASNSGLPPFLVPSSGLNSGFMIAHVTAAALASENKSLAHPASVDSLPTSANQEDHVSMATFAGRRLHEMAHNTAVIVGIELLAAAQGIDFHAPLATAPKLAEVHQRLRTQVSFYGQDRLFAPDIEAAKQMVLAGALSVNCQEVFAGLYLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTB1</accession>
    <name>A0A2S9GTB1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">NAD-dependent aldehyde dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_4329</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000032">
        <property type="protein sequence ID" value="PRC90928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90928">
        <property type="protein sequence ID" value="PRC90928"/>
        <property type="gene ID" value="S2091_4329"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016620">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
        <property type="entry name" value="ALDEHYDE_DEHYDR_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldedh" evidence="5">
        <location>
            <begin position="12"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="253"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC90928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="494" mass="53542" checksum="E2579CA1DBC0257C" modified="2018-07-18" version="1">MNQEQLFINGTWQPARRGRHIDVINPATDTVFATIAAADSDDVADAVHAAKTAFDSGPWPRMSGSARAQVLHKISAAILDQLDKLAELEVRDNGKPLPEARWDISDAAACFTFYADMAEQEERREPELPALPDARFNSQVVRDPVGVVGAIIPWNYPLLMAAWKVAPALAAGCTVVLKPSELTSLTALALADITQQAGLPAGVLNIITGFGSVAGQALISHPAIDKLAFTGSRAIGSVVMQAAAQDIKRVSLELGGKSPLIVFGDSDIDKALEWILFGIFWNQGQVCSATSRVLIERTLYPQLLARLTSEAKRIVIGNGMHEKVQLGPLISREHHQKVCAAIDRALADGATLITGGSTPPANNHSGYFLAPTILADMGTNSWIWNEEVFGPVLCVMPFDTEEEAVTIANNSRYGLAAAVMSTDLARCDRVAQKLRAGIVWINCSQPTFVEAPWGGFKQSGIGRELGRWGFENYLETKQITRFDSSQPWGWYLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTC2</accession>
    <name>A0A2S9GTC2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Mu-like prophage protein Com</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4268</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000031">
        <property type="protein sequence ID" value="PRC90972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90972">
        <property type="protein sequence ID" value="PRC90972"/>
        <property type="gene ID" value="S2091_4268"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019294">
        <property type="entry name" value="Translation_reg_Com"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10122">
        <property type="entry name" value="Mu-like_Com"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="36"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="71" mass="7674" checksum="998B69D216E20F8D" modified="2018-07-18" version="1">MLDIRCGSCSRKLGEGEYITLSIKCPRCGTLNHLRATRSEPASPRASELKTLSHARKSHHSLAGRQTPSGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTR5</accession>
    <name>A0A2S9GTR5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcription elongation factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_4210</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000029">
        <property type="protein sequence ID" value="PRC91114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91114">
        <property type="protein sequence ID" value="PRC91114"/>
        <property type="gene ID" value="S2091_4210"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070063">
        <property type="term" value="F:RNA polymerase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032784">
        <property type="term" value="P:regulation of DNA-templated transcription, elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036953">
        <property type="entry name" value="GreA/GreB_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029462">
        <property type="entry name" value="Rnk_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001437">
        <property type="entry name" value="Tscrpt_elong_fac_GreA/B_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023459">
        <property type="entry name" value="Tscrpt_elong_fac_GreA/B_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30437">
        <property type="entry name" value="PTHR30437"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01272">
        <property type="entry name" value="GreA_GreB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14760">
        <property type="entry name" value="Rnk_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="3" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rnk_N" evidence="2">
        <location>
            <begin position="5"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="domain" description="GreA_GreB" evidence="1">
        <location>
            <begin position="51"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="136" mass="15124" checksum="8B6FAD7B61922271" modified="2018-07-18" version="1">MEVKPPIVVSSFDLERIEQLLESNTHRNLPGIDALLVELNRADIVSPEEIPDNVITMNSKARFIDDATAIEYDLTLVYPHQANLPDTVSIFAPVGSALLGMSVKQTIAWQVPSGRTMKLRILSIIYQPEAQGDFHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTR8</accession>
    <name>A0A2S9GTR8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4201</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000029">
        <property type="protein sequence ID" value="PRC91105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91105">
        <property type="protein sequence ID" value="PRC91105"/>
        <property type="gene ID" value="S2091_4201"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01047">
        <property type="entry name" value="MarR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00598">
        <property type="entry name" value="HTHMARR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00347">
        <property type="entry name" value="HTH_MARR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50995">
        <property type="entry name" value="HTH_MARR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="1">
        <location>
            <begin position="28"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="178" mass="19503" checksum="B73087CDE293C936" modified="2018-07-18" version="1">MNKKNSNIQEPSSISATNAPEISDSAARLEILRKLRIIIRAAAKHSSWIDKQCGVNGAQLWIMQELHEAGALRIGELTLKLAVHQTTTSNLVDGLEKRGYVQKMRDPNDQRAVTVTLTAQGSQMLLAAPKPARGLLPEALMQLDRSSLNVLDQGLLGLLESIDILDEELGMLPLPFTM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTU0</accession>
    <name>A0A2S9GTU0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Serine proteases of the peptidase family S9A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_4146</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000028">
        <property type="protein sequence ID" value="PRC91145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91145">
        <property type="protein sequence ID" value="PRC91145"/>
        <property type="gene ID" value="S2091_4146"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023302">
        <property type="entry name" value="Pept_S9A_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002470">
        <property type="entry name" value="Peptidase_S9A"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02897">
        <property type="entry name" value="Peptidase_S9_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00862">
        <property type="entry name" value="PROLIGOPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015461027" evidence="1">
        <location>
            <begin position="24"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S9_N" evidence="3">
        <location>
            <begin position="32"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S9" evidence="2">
        <location>
            <begin position="506"/>
            <end position="708"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC91145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="708" mass="78278" checksum="5500830DC01CF812" modified="2018-07-18" version="1">MKKQIIHRFFYILLSVISVTSSASPSVAPSSNDPYLWLEDIDSVRSLKWVTQQNDITKDRLSSLPGYTDLYNDALKILTSTSRIPQVEQHGAYFYNLWQDQLHPRGLFRRTTLAELSKPDTQWELLIDIDALSKSEGKLWAFGDAIFLAPENKRCLISLSPGGGDASEIREFDVEAKQFVSDGFTLPAAKSHVSWRDADTLYVATDFGPGSLTKSGYPRIVKVWQRGTALANAPTLYEGDENSMTASAGVVKIHGEKQIDVLTENLTFWNSKVSLIVDGKLQPLALPATASIHGGYHGRLVIWLKEVWVVNGRTYPAGAVVLVDPHASLEKPGAIELVVAPDAHSNVIGVVTTPNGLLVSTLDDVRGRLNRYTLGTAGWEHVKVPFPDNGSLEVKSVDDDTGDAIVQFQTFLTPPSLYFVAADGKSINLLKQQAASFDGSNFEVTQHWTKSLDGTQIPYFVVASKNIKMDGKNPVWMFSYGGFENSLTPSYSGSYEDLHGAYGKLWLERGGVFVLANIRGGGEFGPTWHTSALKENHVKAFEDFEAVAADLSRSKLSSPVHIGIEGRSNGGLLVSATMLRHPELYGAVVCGNPLIDMQRYNKLLAGASWVGEYGDPDVPEQWGYISKYSPYQNLKSGMKLPHVMFYSTTRDDRVHPGHARKMAAKMEAMNYQIEYFENVEGGHHGPVVTEQLATRIARTYSFLWQHLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTX3</accession>
    <name>A0A2S9GTX3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="9">TonB-dependent Receptor Plug Domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_4159</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000028">
        <property type="protein sequence ID" value="PRC91158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91158">
        <property type="protein sequence ID" value="PRC91158"/>
        <property type="gene ID" value="S2091_4159"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039423">
        <property type="entry name" value="TonB-dep_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32552">
        <property type="entry name" value="PTHR32552"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="3 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0675">Receptor</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="2 5" id="KW-0798">TonB box</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015560781" evidence="6">
        <location>
            <begin position="26"/>
            <end position="813"/>
        </location>
    </feature>
    <feature type="domain" description="Plug" evidence="8">
        <location>
            <begin position="78"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="7">
        <location>
            <begin position="308"/>
            <end position="809"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC91158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="813" mass="86975" checksum="A9759C9FBF5E35AA" modified="2018-07-18" version="1">MRHHSGRSVSIIAASLSLAFSTAGAQQTPAMPAMAVTAATAPEPVVTEVPSADQHATKDTGQIKTVVITAQKRTEDASKVPLSISVISGDDLVAQHIVDFADITRSIPNVSFSGGGGSGNAGNGPGLSSIEMRGISSTSGSATVGVYLDDVSMTVGNIYSMGQAEPKFFDLDRVEVLRGPQGTLYGSSSMGGTVKFLSNQPNLKEQEATIYSEVSSTKGGGTNYTANGVFNAVLTPNELAFRIGVEDIHKSGFINQVSQTTGALVAPNINWEADQVVRMAMKWAPTKDLTITPSVFYQQVQSGDIDVSYTQTQNGTPLPMNQTSKLVREPGVDRLLVPSLTVNYGTDYGDLTFVSSYFQRKFNRTQDATAVDSVLLGSLISIPSLAAKVSVLPAAVWFNNDIRQSSEELRFASKPYDPSVSPITWVAGVYIADMHTNITDNEPIFGVNAAFAAAGASTTDPTVLANPVSAGFPNDNSYFGQLHYHDTQQAIFGEANYYFMPNLHATFGLRYLEAKEEFEREGGLYFNNDGTNDGNSHTFANTSGSKATPKIALTWEVDHTDTLYALAGEGFRLGGANLQIPQTLCGLSTPNPASYASDTLWSYEVGDKSRFLDNHLSVNSSLFYVDWKNMQQQIFLGCGYDYNTNVGSATSYGAEVEVKARPISSLLIDFSAGITHATLSDNGGENAGVPGAVAGALIPGVPKFNAALTGQYNFNISDDNFGFARAGVHWTGTSNGGFPTLTNGSIDPDYRRPAYATADFSTGISWEKWELSFFVKNLANNEKIIQHPIVQTNTSEAYRIDPRIIGISVSGKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTZ4</accession>
    <name>A0A2S9GTZ4_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Histidine kinase</fullName>
            <ecNumber evidence="3">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_4078</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="3"/>
    <dbReference type="EMBL" id="PUGF01000027">
        <property type="protein sequence ID" value="PRC91183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91183">
        <property type="protein sequence ID" value="PRC91183"/>
        <property type="gene ID" value="S2091_4078"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038318">
        <property type="entry name" value="KdpD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025201">
        <property type="entry name" value="KdpD_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003852">
        <property type="entry name" value="Sig_transdc_His_kinase_KdpD_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006016">
        <property type="entry name" value="UspA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13493">
        <property type="entry name" value="DUF4118"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13492">
        <property type="entry name" value="GAF_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02702">
        <property type="entry name" value="KdpD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00582">
        <property type="entry name" value="Usp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0407">Ion channel</keyword>
    <keyword evidence="9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="427"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="456"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="485"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="8">
        <location>
            <begin position="680"/>
            <end position="892"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC91183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="899" mass="99896" checksum="D45E58E6E18FD078" modified="2018-07-18" version="1">MIDSRPDPDELLDKIQREDAKQQRGHFKLFFGSCAGVGKTFSMLSAAKAQQLLGVDVIVGVVETHGRRETIAMTEGLDILPLQKINYNDKLRDEFDLDGALKRKPTLILMDELAHSNIPGTRHQKRWQDVEELLAAGINVYSTVNVQHLESLNDIVGQITGIRVWETIPDRVFDMADEITLVDLPPDELLRRLKDGKVYIPHQAERASKNFFRKGNLIALRELALRRTADQVDTQMRDYRADQSIHHVWQAKERLLVCIGPHDSSNKLVRSAARLAASLRADLIAVYIETTALQKLSDKRRDAIHKTLKLAQELGAETSTLSGEKLAPVLLSYARSRNVTKLVIGKSMRPTWSRVLRTSLADELASRTTDVDVYVVGHDIEPEPISGGSHTHYDTLTGAAGSNDVQPWGYLWAAAICIAVTGITEGLLNVFDLANVIMLYLLAAVLIAIRFGRGPSIFASFLSVATFDFFFVPPRYSFSVSDTQYLFTFVIMLAVSLIISNLTANLRYQARIASYRERRTNALNTMSKALSSALMVEQIIEISNEHLVGIFQAKIAILLPDSHEKIRQPLANTSSVPEHLDLGVAQWVYDHQQRAGLGTNTLPANALLYVPLQAPMRTRGVIAIAPLQPRQIFQPEQQQLLDTFAAQIALALERVHYVEVAQDALINIEAERLRNSLLSAISHDLRTPLTAIIGLSSTLVEQSQLSEKIRSELIHGINEEAQHMNSLIINLLDMAKLQSGKVVLNKQWQPIDEVIGSALRISSQLTAKHQIKLEIDKNCPILSFDAVLIERVLCNLIENAVKYGHDQILIKAKVKDDEFILSVIDNGRGLPAGMEEKIFEKFTRGEKESATHGVGLGLAICKAIIETHNGKIWATNAPMQGANISFSLPLGDAPKIENE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GU92</accession>
    <name>A0A2S9GU92_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Peptide methionine sulfoxide reductase MsrB</fullName>
            <ecNumber evidence="3">1.8.4.12</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Peptide-methionine (R)-S-oxide reductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">msrB</name>
        <name evidence="5" type="ORF">S2091_3976</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 3">
            <text>[thioredoxin]-disulfide + H2O + L-methionyl-[protein] = [thioredoxin]-dithiol + L-methionyl-(R)-S-oxide-[protein]</text>
            <dbReference type="Rhea" id="RHEA:24164"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="Rhea" id="RHEA-COMP:12313"/>
            <dbReference type="Rhea" id="RHEA-COMP:12314"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16044"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:45764"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="EC" id="1.8.4.12"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="3">Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the MsrB Met sulfoxide reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.8.4.12" evidence="3"/>
    <dbReference type="EMBL" id="PUGF01000025">
        <property type="protein sequence ID" value="PRC91305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91305">
        <property type="protein sequence ID" value="PRC91305"/>
        <property type="gene ID" value="S2091_3976"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033743">
        <property type="term" value="F:peptide-methionine (R)-S-oxide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030091">
        <property type="term" value="P:protein repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01400">
        <property type="entry name" value="MsrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028427">
        <property type="entry name" value="Met_Sox_Rdtase_MsrB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002579">
        <property type="entry name" value="Met_Sox_Rdtase_MsrB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011057">
        <property type="entry name" value="Mss4-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10173">
        <property type="entry name" value="PTHR10173"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01641">
        <property type="entry name" value="SelR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51316">
        <property type="entry name" value="SSF51316"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00357">
        <property type="entry name" value="TIGR00357"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51790">
        <property type="entry name" value="MSRB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="MsrB" evidence="4">
        <location>
            <begin position="8"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="3">
        <location>
            <position position="119"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="47"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="50"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="96"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="99"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01400"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC91305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="131" mass="14718" checksum="0B47E00C83676A68" modified="2018-07-18" version="1">MKKVIKSEAEWRAELSPIEFQVSRQADTERAFTGKFWDHHVPGIYTCVCCQTPLFSSDAKFDSGCGWPSYFTALNPDHVREIVDKSHGMTRTEIVCNICDAHLGHVFPDGPPPTGLRYCINSASLRFDPTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUC8</accession>
    <name>A0A2S9GUC8_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_3990</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="PUGF01000025">
        <property type="protein sequence ID" value="PRC91319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91319">
        <property type="protein sequence ID" value="PRC91319"/>
        <property type="gene ID" value="S2091_3990"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032408">
        <property type="entry name" value="RisS_PPD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038421">
        <property type="entry name" value="RisS_PPD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16524">
        <property type="entry name" value="RisS_PPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="161"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="8">
        <location>
            <begin position="181"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="7">
        <location>
            <begin position="241"/>
            <end position="445"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC91319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="445" mass="50599" checksum="3747C241002AD69B" modified="2018-07-18" version="1">MHFFREQFVWLKSGLFWRTFFFLTFAIFISLVTWFSSFQLNEEKPRAQQIASQLLSVITITRAALIHSAPEKRQELLFDLASDDGVRIYSLEDSDIIEPAPAGIFMPALQEIVRGKLGAGTIFSRRVNGIDGFWVSFQIDEDDYWIVLDRERFNDVSNLRWISWSALILLMSILAAMIITRLINQPLSRLSQAARAITEGHFLKPLPETGIAEIRDTNKSFNQMAQELARIETDRTLILAGISHDLRTPLARLQLEVELAHLPEQARLGMQSDIVQMDAIIGQFLDFAKPMDATCFSNLDLSHLLETVVRSVQRLPDIKIKYFIAPNMSIGGNGIEISRLINNLIENARRYGKTPGKNYAEIMLVCKPQERNKIMRIVLQFSDNGVGIPEEDTERLLRPFTRVDSARSQANGAGLGLAIVQRIVQQHRASMRLINRKGLLIEVCF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUD7</accession>
    <name>A0A2S9GUD7_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Probable chorismate pyruvate-lyase</fullName>
            <shortName evidence="4">CL</shortName>
            <shortName evidence="4">CPL</shortName>
            <ecNumber evidence="4">4.1.3.40</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ubiC</name>
        <name evidence="5" type="ORF">S2091_3892</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>chorismate = 4-hydroxybenzoate + pyruvate</text>
            <dbReference type="Rhea" id="RHEA:16505"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:17879"/>
            <dbReference type="ChEBI" id="CHEBI:29748"/>
            <dbReference type="EC" id="4.1.3.40"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Cofactor biosynthesis; ubiquinone biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the UbiC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.3.40" evidence="4"/>
    <dbReference type="EMBL" id="PUGF01000024">
        <property type="protein sequence ID" value="PRC91347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91347">
        <property type="protein sequence ID" value="PRC91347"/>
        <property type="gene ID" value="S2091_3892"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00232"/>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008813">
        <property type="term" value="F:chorismate lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042866">
        <property type="term" value="P:pyruvate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006744">
        <property type="term" value="P:ubiquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1410.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01632">
        <property type="entry name" value="UbiC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007440">
        <property type="entry name" value="Chorismate--pyruvate_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028978">
        <property type="entry name" value="Chorismate_lyase_/UTRA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38683">
        <property type="entry name" value="PTHR38683"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04345">
        <property type="entry name" value="Chor_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64288">
        <property type="entry name" value="SSF64288"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4 5" id="KW-0456">Lyase</keyword>
    <keyword evidence="3 4" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0831">Ubiquinone biosynthesis</keyword>
    <feature type="binding site" evidence="4">
        <location>
            <position position="77"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="115"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="175"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC91347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="189" mass="21429" checksum="F64E70CF4F317598" modified="2018-07-18" version="1">MLAKQAARKAQWHHHVNHVQAPKAMRHWLTDAGSLTAKLITHSSKFRVQRVYQQHDFCWADEYTEIGLSKASKVHAREVLLRCDDAPAIYAHTVLPLSSTASQWPLFKALGEKSLGSTLFGDPQVVRGALQFARLQPNHPAMRRAQLLTNKKFDQPLFARRSLFFRRGGVMLVTELFLPAIADLTTHIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUI6</accession>
    <name>A0A2S9GUI6_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_3925</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="PUGF01000024">
        <property type="protein sequence ID" value="PRC91380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91380">
        <property type="protein sequence ID" value="PRC91380"/>
        <property type="gene ID" value="S2091_3925"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="51"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="89"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="119"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="152"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="5">
        <location>
            <begin position="348"/>
            <end position="566"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC91380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="566" mass="62766" checksum="1DB34546C20BEF0A" modified="2018-07-18" version="1">MKQRRSAQNPNETLWRSLKTLSITRVLIALILLILLGLNNSKYIWSIDPHLYRDICLIYIFGGLGFVALQTQLKQYFLWQLSAQVTFDVLVISVLYFFAGGINSSLVILYLFPLASCAILAPLIWALFLASVVALYLLLGSSFQVLQTGSEIAVSSSGLYGAAFLAIVYAVNRLANRLIRQEELAREHGKNLRIQQEINKLVVADMGDGIIVVDSTSRVYASNPATKQMLGITIIPGVSKLSEMPSLLPIADAFYSWRKQVPDIDPVWADTIAFAAVDLHDDSTISDSVMVKGVRRDVVTHLKLRFVNVNAEFGASDERCIIFLQDAFEIENQAQQLKLASMGRLTASIAHEVRNPLSSISYAAALLGESDISPEQGLRLVKIVNDNVVRLNQLIEDILRLSRKAQINVEPFLLKPAVQEILQEFQETHGLAPEVIHLSAPDAMMIRFDPLHLREVLVNLLTNAIRYASGAVSSIQLFVVADLADQLELHVRDDGPGITAEVRAHLFEPFYTTSSRGTGLGLYMARELCLNNGALLDYEYRVTELGVNNANTKANGRFVITFVKPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUJ7</accession>
    <name>A0A2S9GUJ7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Response regulator receiver domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3822</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000023">
        <property type="protein sequence ID" value="PRC91407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91407">
        <property type="protein sequence ID" value="PRC91407"/>
        <property type="gene ID" value="S2091_3822"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="73" mass="8338" checksum="7BF7E3FBDFFC8ECE" modified="2018-07-18" version="1">MNLPDLNGYEVFRILHEDPTTSHIPIMALSSNAFIHDIQKGFNIGFFRYLTKPFEINVLMDAIDTGISMSHIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUL2</accession>
    <name>A0A2S9GUL2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="9">ABC-type transport system involved in resistance to organic solvents ATPase component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_3837</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000023">
        <property type="protein sequence ID" value="PRC91422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91422">
        <property type="protein sequence ID" value="PRC91422"/>
        <property type="gene ID" value="S2091_3837"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-1278">Translocase</keyword>
    <feature type="domain" description="ABC transporter" evidence="8">
        <location>
            <begin position="10"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="248"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="258"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="42"/>
            <end position="49"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC91422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="284" mass="30778" checksum="8E33BF0578805434" modified="2018-07-18" version="1">MNNLPNQTVVEISNVCTRFGDHIVHSGVDLEVRKAEIFALIGGSGSGKSTLLREMIMLQRPDSGSIQVLGEPLEHLGEQQATDLRKRWGVMFQHGGLFGSLTVQQNIGLPMREHTNLDDALIDEIADWKLTMTGLKSAVGAQYPSELSGGMLKRASLARALVLDPELLFLDEPTTGLDPESASEIDELVCKLRNQSGLTIVMITHDLDLLWQVSDRVAVLANGKVQAMGSMQELSTNDNPAIKVFFDGPRGRAAQDQEQRLPHTSTNAAKATNATSGSSPSKPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUL8</accession>
    <name>A0A2S9GUL8_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Arginine biosynthesis bifunctional protein ArgJ</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="7">Glutamate N-acetyltransferase</fullName>
                <ecNumber evidence="7">2.3.1.35</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="7">Ornithine acetyltransferase</fullName>
                <shortName evidence="7">OATase</shortName>
            </alternativeName>
            <alternativeName>
                <fullName evidence="7">Ornithine transacetylase</fullName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="7">Amino-acid acetyltransferase</fullName>
                <ecNumber evidence="7">2.3.1.1</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="7">N-acetylglutamate synthase</fullName>
                <shortName evidence="7">AGSase</shortName>
            </alternativeName>
        </domain>
        <component>
            <recommendedName>
                <fullName evidence="7">Arginine biosynthesis bifunctional protein ArgJ alpha chain</fullName>
            </recommendedName>
        </component>
        <component>
            <recommendedName>
                <fullName evidence="7">Arginine biosynthesis bifunctional protein ArgJ beta chain</fullName>
            </recommendedName>
        </component>
    </protein>
    <gene>
        <name evidence="7" type="primary">argJ</name>
        <name evidence="8" type="ORF">S2091_3949</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>L-glutamate + N(2)-acetyl-L-ornithine = L-ornithine + N-acetyl-L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:15349"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:44337"/>
            <dbReference type="ChEBI" id="CHEBI:46911"/>
            <dbReference type="ChEBI" id="CHEBI:57805"/>
            <dbReference type="EC" id="2.3.1.35"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>acetyl-CoA + L-glutamate = CoA + H(+) + N-acetyl-L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:24292"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:44337"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="EC" id="2.3.1.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Amino-acid biosynthesis; L-arginine biosynthesis; L-ornithine and N-acetyl-L-glutamate from L-glutamate and N(2)-acetyl-L-ornithine (cyclic): step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="7">Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 1/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 7">Heterotetramer of two alpha and two beta chains.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="7">Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the ArgJ family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.35" evidence="7"/>
    <dbReference type="EC" id="2.3.1.1" evidence="7"/>
    <dbReference type="EMBL" id="PUGF01000024">
        <property type="protein sequence ID" value="PRC91404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91404">
        <property type="protein sequence ID" value="PRC91404"/>
        <property type="gene ID" value="S2091_3949"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00068">
        <property type="reaction ID" value="UER00106"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004042">
        <property type="term" value="F:acetyl-CoA:L-glutamate N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004358">
        <property type="term" value="F:glutamate N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0103045">
        <property type="term" value="F:methione N-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006526">
        <property type="term" value="P:arginine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02152">
        <property type="entry name" value="OAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.340">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01106">
        <property type="entry name" value="ArgJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002813">
        <property type="entry name" value="Arg_biosynth_ArgJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016117">
        <property type="entry name" value="ArgJ-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042195">
        <property type="entry name" value="ArgJ_beta_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23100">
        <property type="entry name" value="PTHR23100"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01960">
        <property type="entry name" value="ArgJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56266">
        <property type="entry name" value="SSF56266"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00120">
        <property type="entry name" value="ArgJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="5 7" id="KW-0068">Autocatalytic cleavage</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7 8" id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_5023394981" description="Arginine biosynthesis bifunctional protein ArgJ alpha chain" evidence="7">
        <location>
            <begin position="1"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023394980" description="Arginine biosynthesis bifunctional protein ArgJ beta chain" evidence="7">
        <location>
            <begin position="198"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="7">
        <location>
            <position position="198"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="161"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="187"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="198"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="284"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="408"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="413"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole" evidence="7">
        <location>
            <position position="124"/>
        </location>
    </feature>
    <feature type="site" description="Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole" evidence="7">
        <location>
            <position position="125"/>
        </location>
    </feature>
    <feature type="site" description="Cleavage; by autolysis" evidence="7">
        <location>
            <begin position="197"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006774"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC91404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="413" mass="43668" checksum="11E075593FC02C5C" modified="2018-07-18" version="1">MAVNSPLPIASQLHPVAGIQLGFAQAGIRKADRKDLLVMKLAPTATVAGVLTANRFCAAPVQVCKAHLSGASMVSGAPIRALVINTGNANAGTGVTGLVAANATCSALAELLECEPSQVLPFSTGVILEPLPVERLIAGLPAAIDNLKEDNWYSAAEAIMTTDTQPKAASRQVKIGEHTITLTGISKGAGMIMPNMATMLGFLAMDVKVAQPVLEQLVKQAANRSFNCISIDGDTSTNDAFMLIATGVSDLEITDTDSPEYAALMAAVVSLSQQLAQMIVRDGEGATKFMTVTVEQGRDVEECRQIAYSIANSPLVKTAFFASDPNLGRLLMAIGKAGVHDLDVGQVDLYLDDVLVVKHGGRNPDYQESDGQRVMKQSEIVTRVLLARGTARATVWTCDLSHEYVTINADYRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GV12</accession>
    <name>A0A2S9GV12_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Ring hydroxylating alpha subunit (Catalytic domain)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_3666</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000021">
        <property type="protein sequence ID" value="PRC91550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91550">
        <property type="protein sequence ID" value="PRC91550"/>
        <property type="gene ID" value="S2091_3666"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.102.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017941">
        <property type="entry name" value="Rieske_2Fe-2S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036922">
        <property type="entry name" value="Rieske_2Fe-2S_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015879">
        <property type="entry name" value="Ring_hydroxy_dOase_asu_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001663">
        <property type="entry name" value="Rng_hydr_dOase-A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43756">
        <property type="entry name" value="PTHR43756"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00355">
        <property type="entry name" value="Rieske"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00848">
        <property type="entry name" value="Ring_hydroxyl_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00090">
        <property type="entry name" value="RNGDIOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50022">
        <property type="entry name" value="SSF50022"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51296">
        <property type="entry name" value="RIESKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rieske" evidence="6">
        <location>
            <begin position="40"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC91550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="379" mass="43448" checksum="AFBEFAB00B8E5545" modified="2018-07-18" version="1">MSDLATFAKLVRSTAQLPVSVYFDESLLQREIKQLFQQGPRYIGHELMVPNVGDFATLASENEGRMLVRSERGIELLSNVCRHRQALMFGGSGGKGNQTTRGNATNIVCPLHRWTYDLKGELLGAPHFDESPCLNLANTKLQSWNGLLFEQNGYNVMEKLSQLSVTKDLDFSGYMLDHVEVHDCDYNWKTFIEVYLEDYHVEPFHPGLGSFVACDDLRWEFGADYSVQTVGVNSGLLKSGSKTYQAWQEQVLKFRNGVVPPYGAIWLTLYPNIMVEWYPHVLVVSTLWPQGVGKTRNVVEFYYPEEIVLFEREFIEAERAAYMETCIEDDEIGFRMDAGRRILFERGENQVGPYQSPMEDGMQHFHEWFRANMAIDENS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GV26</accession>
    <name>A0A2S9GV26_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative secreted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3693</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000021">
        <property type="protein sequence ID" value="PRC91577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91577">
        <property type="protein sequence ID" value="PRC91577"/>
        <property type="gene ID" value="S2091_3693"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010634">
        <property type="entry name" value="DUF1223"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36057">
        <property type="entry name" value="PTHR36057"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06764">
        <property type="entry name" value="DUF1223"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015580839" evidence="1">
        <location>
            <begin position="21"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="253" mass="28040" checksum="E6939570BAD3F2D8" modified="2018-07-18" version="1">MKHLLFIVAVQFAWLTSSPAAEVCSKSSPSYTIALLELYTSEGCSSCPPADKTVKQLYQTPGLTADNVIPLALHVDYWDYIGWKDPYAQPLHTERQNYLSALSGSRTIYTPEFFIGGLEFRNWRSDLLRAVKTINRQPALASIDIKLEKNVTNKLTLQIDTKTSQASELHYVLVEQGLSSSVSAGENKGETLQHDAVARDWGTVIKLTPELQNTSLVHLNIPINSKQKNLSVVAFVQNPQGKILQALSLPLCN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GV35</accession>
    <name>A0A2S9GV35_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PIN domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3703</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000021">
        <property type="protein sequence ID" value="PRC91587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91587">
        <property type="protein sequence ID" value="PRC91587"/>
        <property type="gene ID" value="S2091_3703"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002716">
        <property type="entry name" value="PIN_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10130">
        <property type="entry name" value="PIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="SSF88723"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PINc" evidence="1">
        <location>
            <begin position="7"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF10130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="140" mass="15959" checksum="96B4DC4FBFC579FF" modified="2018-07-18" version="1">MNSKTIVLDANILIRAVLGKRARELIFKYAATIKFFAPEIAYADARKYLPALLEKRGIQSTTAMQLLNNLTVIIQPIELDLYIELKQQALERIAIRDADDWPILACAMRFDCPVWTEDVDCFGAGIATWTTDRVELYFSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVG4</accession>
    <name>A0A2S9GVG4_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 4">Triosephosphate isomerase</fullName>
            <shortName evidence="3">TIM</shortName>
            <shortName evidence="3">TPI</shortName>
            <ecNumber evidence="3 4">5.3.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Triose-phosphate isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">tpiA</name>
        <name evidence="5" type="ORF">S2091_3638</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3 4">
            <text>D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate</text>
            <dbReference type="Rhea" id="RHEA:18585"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="5.3.1.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 4">Carbohydrate biosynthesis; gluconeogenesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 4">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate from glycerone phosphate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 4">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the triosephosphate isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.1" evidence="3 4"/>
    <dbReference type="EMBL" id="PUGF01000020">
        <property type="protein sequence ID" value="PRC91700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91700">
        <property type="protein sequence ID" value="PRC91700"/>
        <property type="gene ID" value="S2091_3638"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00189"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00138"/>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004807">
        <property type="term" value="F:triose-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00311">
        <property type="entry name" value="TIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00147_B">
        <property type="entry name" value="TIM_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035990">
        <property type="entry name" value="TIM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022896">
        <property type="entry name" value="TrioseP_Isoase_bac/euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000652">
        <property type="entry name" value="Triosephosphate_isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020861">
        <property type="entry name" value="Triosephosphate_isomerase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21139">
        <property type="entry name" value="PTHR21139"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00121">
        <property type="entry name" value="TIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51351">
        <property type="entry name" value="SSF51351"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00419">
        <property type="entry name" value="tim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00171">
        <property type="entry name" value="TIM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51440">
        <property type="entry name" value="TIM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 3 4" id="KW-0312">Gluconeogenesis</keyword>
    <keyword evidence="3 4" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="2 3 4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="3">
        <location>
            <begin position="11"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="3">
        <location>
            <begin position="239"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="active site" description="Electrophile" evidence="3">
        <location>
            <position position="101"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="173"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="179"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="218"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC91700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="257" mass="26866" checksum="3FDB6F6138E98122" modified="2018-07-18" version="1">MKQRRPLIAGNWKMNGSLVTNAVLLSELQSGIKNLSASAADCDVAVCVPAPYLAQVQVALQTSSIAWGAQDVSAQAGGAYTGEMSVSMLKDFSCAYAIVGHSERRVYHAESDALVAEKTLRLLEAGITPIVCVGETLQERKAGLTEATVARQLNAVLSVLDAAALAKIVVAYEPVWAIGTGITATPEMAQQVHAFLRSQLALMNAELAEQVQILYGGSMKPDNAVALLAMKDIDGGLIGGAALKSIDFLGIIAAAIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVI5</accession>
    <name>A0A2S9GVI5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HpnD: squalene synthase HpnD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3658</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000020">
        <property type="protein sequence ID" value="PRC91720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91720">
        <property type="protein sequence ID" value="PRC91720"/>
        <property type="gene ID" value="S2091_3658"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004311">
        <property type="term" value="F:farnesyltranstransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016767">
        <property type="term" value="F:geranylgeranyl-diphosphate geranylgeranyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016117">
        <property type="term" value="P:carotenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00683">
        <property type="entry name" value="Trans_IPPS_HH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017828">
        <property type="entry name" value="SQ_synth_HpnD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002060">
        <property type="entry name" value="Squ/phyt_synthse"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019845">
        <property type="entry name" value="Squalene/phytoene_synthase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044843">
        <property type="entry name" value="Trans_IPPS_bact-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033904">
        <property type="entry name" value="Trans_IPPS_HH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00494">
        <property type="entry name" value="SQS_PSY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01212">
        <property type="entry name" value="Phytoene_synthase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="SSF48576"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03465">
        <property type="entry name" value="HpnD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01044">
        <property type="entry name" value="SQUALEN_PHYTOEN_SYN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01045">
        <property type="entry name" value="SQUALEN_PHYTOEN_SYN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="277" mass="31515" checksum="2F54DA42C613F08E" modified="2018-07-18" version="1">MSPDEYCQQKAAQSGSSFYYSFLFLPKPRRLAITALYAFCREVDDAVDETSDATVAQNKLLWWRSEINAMLAGKPTHPVTRALQPHLATYQLEGKHLLAIIDGMEMDLSQTRYLDYIGLQRYCWHVAGVVGILSASIFGVTNPKTLEFAEKLGLAFQLTNIIRDVGDDARKGRIYLPVNELQQFGVTAADILNAKHSDQFVALMQFQYERAQACYEQAFALLPQEDRRAQRTSLIMAAIYRTLLVEVKDDGFHVLNQRISLTPIRKLWLAWITYVRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVM9</accession>
    <name>A0A2S9GVM9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CadR-PbrR: Cd(II)/Pb(II)-responsive transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3516</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000019">
        <property type="protein sequence ID" value="PRC91761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91761">
        <property type="protein sequence ID" value="PRC91761"/>
        <property type="gene ID" value="S2091_3516"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045893">
        <property type="term" value="P:positive regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04784">
        <property type="entry name" value="HTH_CadR-PbrR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011791">
        <property type="entry name" value="CadR-PbrR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000551">
        <property type="entry name" value="MerR-type_HTH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13411">
        <property type="entry name" value="MerR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00040">
        <property type="entry name" value="HTHMERR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00422">
        <property type="entry name" value="HTH_MERR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02047">
        <property type="entry name" value="CadR-PbrR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50937">
        <property type="entry name" value="HTH_MERR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH merR-type" evidence="1">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="141" mass="15762" checksum="68270683119E4673" modified="2018-07-18" version="1">MRIGELGQATGVEVETIRYYEKAGLLAEPLRLANGYRSYNKAHLERLSFIRHCRALDMPLAEITRLVEFMTHPSNDCGDINSLIDQQINRVRARLASMQALENQLTTLRARCDATHFGLECGILHELVAAAHGEACACHSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVR0</accession>
    <name>A0A2S9GVR0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Sel1 repeat</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3570</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000019">
        <property type="protein sequence ID" value="PRC91815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91815">
        <property type="protein sequence ID" value="PRC91815"/>
        <property type="gene ID" value="S2091_3570"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015730156" evidence="1">
        <location>
            <begin position="23"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="233" mass="26023" checksum="A25B33F8E0EA4319" modified="2018-07-18" version="1">MKKFLTYIFWVCLVINSNTASADWFVSSETKALILKADLGDINAQIKVAVAYDLGKGAPKDIDNAKKYYKMAAEQGNAEAQNSLGSVLQSEKHFADAMPWYEKASAQGHAQATNNLAYLYDLGLGVSQDRHKGFELYSRAAELGWAESMWNIANMYMAGQLGEPDMVMGCVWTIRANRFASADAPKLKNYLAHVVDQFQHRLSEIQFNTCKTQGEDWEPSLAKAEQNRQPRAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVZ3</accession>
    <name>A0A2S9GVZ3_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_3436</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="PUGF01000018">
        <property type="protein sequence ID" value="PRC91880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91880">
        <property type="protein sequence ID" value="PRC91880"/>
        <property type="gene ID" value="S2091_3436"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="8">
        <location>
            <begin position="183"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="7">
        <location>
            <begin position="282"/>
            <end position="513"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC91880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="514" mass="56787" checksum="652585B67DA7F9CD" modified="2018-07-18" version="1">MHRIYLRLIAIFVVIVTVVLTISGTYSQYKLSERLEMRDSQLRLSVLARLQISLPPALWNLDKSKVDSLLESEMIAPEVEEIRVYDADGSNLFSGKIRNAVGKIVNVNTNIPMEDSKVSASLAYTTPDTNNRNSENKAAIGHIEVKFSRAPINAVLSAELKHKILEILALDLILVVALSFSLRMVFVPLTQLRDSLNDLATHETEEVEELPENRRDEFGEVAGGFNRIQRKLKSTIENTRQAEDVARRASVSAEQALQNLRTAQNSLVQAERLASLGGLVAGVAHEINTPLGITLTGASTLQEATELIQTAMNTGNIKKSEMVRYLETAIESSRLILGNTHRAAELIQSFKQIAVDQTNEIKRPFNVKEYIEEVLMCLAPKLKKTKIQVSVNCATEIELNTYSGAFAQILTNLIMNALTHAYEVDDIGHIDINVQMLNSVLELSFCDDGKGIPAEYLGKIFDPFFTTKLGKGGSGLGLNIVYNLIAKQLDGSIIVESVLGKGTRFIIRIPCSRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GW31</accession>
    <name>A0A2S9GW31_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Integral membrane protein interacts with FtsH</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_3476</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the BI1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000018">
        <property type="protein sequence ID" value="PRC91920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91920">
        <property type="protein sequence ID" value="PRC91920"/>
        <property type="gene ID" value="S2091_3476"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006214">
        <property type="entry name" value="Bax_inhibitor_1-related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23291">
        <property type="entry name" value="PTHR23291"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01027">
        <property type="entry name" value="Bax1-I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="27"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="57"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="81"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="114"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="146"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="169"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="207"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC91920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="230" mass="25082" checksum="839F595FE00C9BD3" modified="2018-07-18" version="1">MSQNLEQSIVYGNDGALIRHRVLRNTYWLLALSMIPTVLGAWIGVEMNFSLFPGRPGISFMVFMAIAFGFMFAIEKTKESALGVAVLLGFTFFMGLMLSRLISYTLGYTNGASLIMTAFGGTATILAVMASIATTSKRDFSGLGKWLFVGLMVIIVAGIANIYLQLPALYLTVSVVAIGIFSAYILYDVQQIINGGETNYISATLRIYLDVYNIFVNLLSLLGIFGGNRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GW62</accession>
    <name>A0A2S9GW62_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3283</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000017">
        <property type="protein sequence ID" value="PRC91941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91941">
        <property type="protein sequence ID" value="PRC91941"/>
        <property type="gene ID" value="S2091_3283"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="72" mass="8229" checksum="D8EC9BB39B52EE09" modified="2018-07-18" version="1">MQIGMSLDKAVANQLSLIDLRLDSSFNLLATFYKVCGVAHLVAQYIIYLFSLKLMFAYAHTNELTMRYHPIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GW70</accession>
    <name>A0A2S9GW70_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Nitrogen regulatory protein PII</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_3302</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the P(II) protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000017">
        <property type="protein sequence ID" value="PRC91960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91960">
        <property type="protein sequence ID" value="PRC91960"/>
        <property type="gene ID" value="S2091_3302"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030234">
        <property type="term" value="F:enzyme regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006808">
        <property type="term" value="P:regulation of nitrogen utilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002187">
        <property type="entry name" value="N-reg_PII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011322">
        <property type="entry name" value="N-reg_PII-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015867">
        <property type="entry name" value="N-reg_PII/ATP_PRibTrfase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017918">
        <property type="entry name" value="N-reg_PII_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002332">
        <property type="entry name" value="N-reg_PII_urydylation_site"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30115">
        <property type="entry name" value="PTHR30115"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00543">
        <property type="entry name" value="P-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039144">
        <property type="entry name" value="GlnB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00340">
        <property type="entry name" value="PIIGLNB"/>
    </dbReference>
    <dbReference type="SMART" id="SM00938">
        <property type="entry name" value="P-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54913">
        <property type="entry name" value="SSF54913"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00638">
        <property type="entry name" value="PII_GLNB_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51343">
        <property type="entry name" value="PII_GLNB_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00496">
        <property type="entry name" value="PII_GLNB_UMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="modified residue" description="O-UMP-tyrosine" evidence="2">
        <location>
            <position position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR039144-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR602187-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC91960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="112" mass="12203" checksum="1C4A72E56C5C7C79" modified="2018-07-18" version="1">MKLITAIIKPFKLDEVREALSAIGVQGITATEVKGFGRQKGHTELYRGAEYVVDFLPKTKIEAAVNDDIVDRAIEAIETAGRTGKIGDGKIFVFDLLQVVRIRTGETGNDAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GW90</accession>
    <name>A0A2S9GW90_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Growth inhibitor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3337</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000017">
        <property type="protein sequence ID" value="PRC91995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91995">
        <property type="protein sequence ID" value="PRC91995"/>
        <property type="gene ID" value="S2091_3337"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003477">
        <property type="entry name" value="PemK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011067">
        <property type="entry name" value="Plasmid_toxin/cell-grow_inhib"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33988">
        <property type="entry name" value="PTHR33988"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02452">
        <property type="entry name" value="PemK_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="116" mass="12479" checksum="7B61AC331238672A" modified="2018-07-18" version="1">MVKRVKFGRGDIVLVNLEPAQGREQKGEHRPALVFSTSVFNAMGVVLIAPITQGGDFARHAGFAVSLSGSGTKTQGVALVNQVRMLDLEERGAKKIETAPDFVVEDALARFQTIVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWB8</accession>
    <name>A0A2S9GWB8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Peptidase family M48</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">S2091_3367</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="7 8">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="7 8">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the peptidase M48 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000017">
        <property type="protein sequence ID" value="PRC92025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92025">
        <property type="protein sequence ID" value="PRC92025"/>
        <property type="gene ID" value="S2091_3367"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071586">
        <property type="term" value="P:CAAX-box protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07343">
        <property type="entry name" value="M48A_Zmpste24p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027057">
        <property type="entry name" value="CAXX_Prtase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001915">
        <property type="entry name" value="Peptidase_M48"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032456">
        <property type="entry name" value="Peptidase_M48_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01435">
        <property type="entry name" value="Peptidase_M48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16491">
        <property type="entry name" value="Peptidase_M48_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 8" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1 8" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 7 8" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="70"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="101"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="143"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="179"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="293"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="335"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M48_N" evidence="11">
        <location>
            <begin position="28"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M48" evidence="10">
        <location>
            <begin position="209"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="280"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="6">
        <location>
            <position position="368"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="279"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="283"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="364"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR627057-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR627057-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF16491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PRC92025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="432" mass="48688" checksum="A4CF3E7CDB382B7D" modified="2018-07-18" version="1">MDSFAFSVLFIVFLSLTLGCRFWLASRQIRFVQQHRATVPAQFAEKITLASHQKAADYTIAKAKLGIIDLFLGALILLALTLFGGLQWLSTHLIPLLGTGMSYQIGLLVSFAFITSLIDLPMDYYRQFVLEEKFGFNKMTVRLFFTDMIKNSVIGAAIGLPLCWVVLKLMGSAGDLWWLYAWLVWSGFQLLMMVLYPSVIAPLFNKFKPLEDESLKARIEGLMQRTGFASKGLFIMDGSKRSAHGNAYFSGFGASKRIVFFDTLIERLAPQEIEAVLAHELGHFKKKHIVQRIVLIFILSLGFLALLGFLKEQVWFYTGLGVDPLLIGTNNSNDAMALLLFMLTLPLFTFFFSPISAITSRKHEFEADDFAAYHTKADDLISALVKMYDDNASTLTPDPMYSTFYDSHPSAAVRINHLNNHYQLNNAKEHHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWS5</accession>
    <name>A0A2S9GWS5_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Phosphatidate cytidylyltransferase</fullName>
            <ecNumber evidence="7">2.7.7.41</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_3067</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>a 1,2-diacyl-sn-glycero-3-phosphate + CTP + H(+) = a CDP-1,2-diacyl-sn-glycerol + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:16229"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <dbReference type="ChEBI" id="CHEBI:58332"/>
            <dbReference type="ChEBI" id="CHEBI:58608"/>
            <dbReference type="EC" id="2.7.7.41"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Phospholipid metabolism; CDP-diacylglycerol biosynthesis; CDP-diacylglycerol from sn-glycerol 3-phosphate: step 3/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the CDS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.41" evidence="7"/>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92151">
        <property type="protein sequence ID" value="PRC92151"/>
        <property type="gene ID" value="S2091_3067"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00557">
        <property type="reaction ID" value="UER00614"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004605">
        <property type="term" value="F:phosphatidate cytidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016024">
        <property type="term" value="P:CDP-diacylglycerol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000374">
        <property type="entry name" value="PC_trans"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01315">
        <property type="entry name" value="CDS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 7 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="6"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="51"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="76"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="108"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="133"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="206"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003938"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC92151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="278" mass="30226" checksum="95FED81520B72ED8" modified="2018-07-18" version="1">MLKTRILTAAVLLAVLLPVLFFGAPLAINILCALFFCAACWESLRLFGHRLLIPATIVWTGIFIWLAFMGNTAQFFPVWALGIAAWIAKFIPSLKFGLPPQASASNRIFSTLYLISILACFLAILIFQRHSTSYLLSVLVIVWVADIGAYFSGKAFGKRKLAPTISPGKSWEGAIGGWVCVVALGAISTQIPFFSDSFSVTLQHHWGWLGLCLVLSLLTALSVVGDLVESQLKRRAQIKDSSNLLPGHGGVLDRIDALISVLPMAILIEILVEITSKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWU0</accession>
    <name>A0A2S9GWU0_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Malate dehydrogenase</fullName>
            <ecNumber evidence="3">1.1.1.37</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">mdh</name>
        <name evidence="9" type="ORF">S2091_3096</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the reversible oxidation of malate to oxaloacetate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>(S)-malate + NAD(+) = H(+) + NADH + oxaloacetate</text>
            <dbReference type="Rhea" id="RHEA:21432"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15589"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.37"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the LDH/MDH superfamily. MDH type 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.37" evidence="3"/>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92180">
        <property type="protein sequence ID" value="PRC92180"/>
        <property type="gene ID" value="S2091_3096"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030060">
        <property type="term" value="F:L-malate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006108">
        <property type="term" value="P:malate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01517">
        <property type="entry name" value="Malate_dehydrog_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001557">
        <property type="entry name" value="L-lactate/malate_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022383">
        <property type="entry name" value="Lactate/malate_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001236">
        <property type="entry name" value="Lactate/malate_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015955">
        <property type="entry name" value="Lactate_DH/Glyco_Ohase_4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010945">
        <property type="entry name" value="Malate_DH_type2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23382">
        <property type="entry name" value="PTHR23382"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02866">
        <property type="entry name" value="Ldh_1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00056">
        <property type="entry name" value="Ldh_1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000102">
        <property type="entry name" value="Lac_mal_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56327">
        <property type="entry name" value="SSF56327"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01759">
        <property type="entry name" value="MalateDH-SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0520">NAD</keyword>
    <keyword evidence="2 3 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="Ldh_1_N" evidence="7">
        <location>
            <begin position="6"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="domain" description="Ldh_1_C" evidence="8">
        <location>
            <begin position="160"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3 4">
        <location>
            <position position="190"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="12"/>
            <end position="18"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="95"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3 5">
        <location>
            <position position="101"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="108"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="115"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="132"/>
            <end position="134"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3 5">
        <location>
            <position position="134"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3 5">
        <location>
            <position position="165"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000102-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000102-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC92180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="329" mass="35388" checksum="D2DCF507DFB8F97B" modified="2018-07-18" version="1">MTKSPMRVSVSGAAGQIGYALLFRIANGDMLGKDQPVILQLLEIADEKAQKALQGVMMEINDCAFPLLAGMTAHSDPMTAFKDIDFALLVGARPRGPGMERKDLLEANAQIFTVQGKALDAVAKRTVKVLVVGNPANTNAYIAMKSAPGLPSKNFTAMLRLDHNRALSQVAAKVNKSVTEIEKMCVWGNHSPTMYADYRFATTDGKSVKEMINDDVWNKDVFLPTVGKRGAAIIEARGLSSAASAANAAIDHVRDWALGTNGKWTTMGIPSDGSYGIPEGTMFGFPVTTANGEYQIVQGLAIDAFSQERINLTLKELSEEREGVKHLVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWX1</accession>
    <name>A0A2S9GWX1_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">3-oxoacyl-[acyl-carrier-protein] synthase 3</fullName>
            <ecNumber evidence="8">2.3.1.180</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">3-oxoacyl-[acyl-carrier-protein] synthase III</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Beta-ketoacyl-ACP synthase III</fullName>
            <shortName evidence="8">KAS III</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">fabH</name>
        <name evidence="11" type="ORF">S2091_3128</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>acetyl-CoA + H(+) + malonyl-[ACP] = 3-oxobutanoyl-[ACP] + CO2 + CoA</text>
            <dbReference type="Rhea" id="RHEA:12080"/>
            <dbReference type="Rhea" id="RHEA-COMP:9623"/>
            <dbReference type="Rhea" id="RHEA-COMP:9625"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:78449"/>
            <dbReference type="ChEBI" id="CHEBI:78450"/>
            <dbReference type="EC" id="2.3.1.180"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="8">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="8">The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the thiolase-like superfamily. FabH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.180" evidence="8"/>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92212">
        <property type="protein sequence ID" value="PRC92212"/>
        <property type="gene ID" value="S2091_3128"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00094"/>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033818">
        <property type="term" value="F:beta-ketoacyl-acyl-carrier-protein synthase III activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01815">
        <property type="entry name" value="FabH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013751">
        <property type="entry name" value="ACP_syn_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013747">
        <property type="entry name" value="ACP_syn_III_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004655">
        <property type="entry name" value="FabH_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08545">
        <property type="entry name" value="ACP_syn_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08541">
        <property type="entry name" value="ACP_syn_III_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00747">
        <property type="entry name" value="fabH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="4 8" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="2 8" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="5 8" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ACP_syn_III" evidence="10">
        <location>
            <begin position="115"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="domain" description="ACP_syn_III_C" evidence="9">
        <location>
            <begin position="238"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="region of interest" description="ACP-binding" evidence="8">
        <location>
            <begin position="255"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="121"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="254"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF08545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC92212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="327" mass="34313" checksum="8B4D466C641E2E86" modified="2018-07-18" version="1">MKIFSKITGTGSYLPPKRVTNHDLTKQLAEQGVETSDEWIFTRSGISARHFAESDVSASDLAVHAALRAIEMSGLDKNQIDLIILATSTPDHLGGFPSTACIVQKKLGIAGCAAFDVQAVCSGFIYAVSVADAMIKAGNNKNVLVIGAEVFSRILDFNDRGTCVLFGDGAGAVVMSASNEPGVLATKLHADGNYSHILSVPGKAAGGVVEGSAFVYMDGPAVFKLAVSVLEKVAREVLEIANMTSADLDWLVPHQANIRIMQSTAKKLHLPLDKVIVTVDQHGNTSAASIPLALDCGVRDGRIKPGQTVLIEGVGGGFTWGAAVVKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWZ4</accession>
    <name>A0A2S9GWZ4_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6">30S ribosomal protein S18</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rpsR</name>
        <name evidence="8" type="ORF">S2091_3159</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 6">Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6 7">Belongs to the bacterial ribosomal protein bS18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92243">
        <property type="protein sequence ID" value="PRC92243"/>
        <property type="gene ID" value="S2091_3159"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00270">
        <property type="entry name" value="Ribosomal_S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001648">
        <property type="entry name" value="Ribosomal_S18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018275">
        <property type="entry name" value="Ribosomal_S18_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036870">
        <property type="entry name" value="Ribosomal_S18_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13479">
        <property type="entry name" value="PTHR13479"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01084">
        <property type="entry name" value="Ribosomal_S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00974">
        <property type="entry name" value="RIBOSOMALS18"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46911">
        <property type="entry name" value="SSF46911"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00165">
        <property type="entry name" value="S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00057">
        <property type="entry name" value="RIBOSOMAL_S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 6 7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC92243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="94" mass="11072" checksum="A2EB61EE2E869896" modified="2018-07-18" version="1">MAFGKKFDKSKLKQKRQQQNPLFKRKKFCRFTAAHVEQVDYKDVDTLKDFVQENGKIMPARLTGTKALYQRQVDTAIKRARYLALLPYTDLHHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GX11</accession>
    <name>A0A2S9GX11_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6">30S ribosomal protein S6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rpsF</name>
        <name evidence="8" type="ORF">S2091_3157</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 6">Binds together with S18 to 16S ribosomal RNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the bacterial ribosomal protein bS6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92241">
        <property type="protein sequence ID" value="PRC92241"/>
        <property type="gene ID" value="S2091_3157"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00473">
        <property type="entry name" value="bS6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00360">
        <property type="entry name" value="Ribosomal_S6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000529">
        <property type="entry name" value="Ribosomal_S6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020814">
        <property type="entry name" value="Ribosomal_S6_plastid/chlpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035980">
        <property type="entry name" value="Ribosomal_S6_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014717">
        <property type="entry name" value="Transl_elong_EF1B/ribosomal_S6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21011">
        <property type="entry name" value="PTHR21011"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01250">
        <property type="entry name" value="Ribosomal_S6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54995">
        <property type="entry name" value="SSF54995"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00166">
        <property type="entry name" value="S6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 6 8" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6" id="KW-0699">rRNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="96"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC92241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="122" mass="13955" checksum="979CF27730A027A6" modified="2018-07-18" version="1">MRHYEIVFIVHPDQSEQVPAMIERYKASVIARNGQVHRVEDWGRRQLAYMIQKLAKAHYVCMNIECDSDTLVELETSFKFNDAVLRHLTVKVKKAETAPSPMMKAVQKEDAAKTQRAEAPAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GX30</accession>
    <name>A0A2S9GX30_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative nucleic acid-binding protein contains PIN domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2933</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92274">
        <property type="protein sequence ID" value="PRC92274"/>
        <property type="gene ID" value="S2091_2933"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002716">
        <property type="entry name" value="PIN_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01850">
        <property type="entry name" value="PIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="SSF88723"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PINc" evidence="1">
        <location>
            <begin position="2"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="121" mass="13863" checksum="22B0B7B8CD8A999D" modified="2018-07-18" version="1">MILADTSIWIDLFRGTNQLQHLLFRNEICIHPFIIGELACGSLPDRKNTLHLLHELPFVPVAKHHEVLFFIETHKLAARGIGYVDMHLLASTALDGCKLLSRDKRLHSIAQELNLAYYQDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GX67</accession>
    <name>A0A2S9GX67_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2960</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92301">
        <property type="protein sequence ID" value="PRC92301"/>
        <property type="gene ID" value="S2091_2960"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000944">
        <property type="entry name" value="Tscrpt_reg_Rrf2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33221">
        <property type="entry name" value="PTHR33221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02082">
        <property type="entry name" value="Rrf2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51197">
        <property type="entry name" value="HTH_RRF2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="156" mass="16893" checksum="23369B9DC701946F" modified="2018-07-18" version="1">MPTSTRFAVAIHILSNIAMHPGQAVRSEDIARSVNTNPTVVRRILSTLADVGLTHAQMGQGGGNLLAKPANKITLLDIYQAVEEPQFFALHRSKPNPACYIGHNITPVLEEEFDRITKALEHSLAKTTLADIVKNVETCAGFPFVPKSHGDATKSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXC8</accession>
    <name>A0A2S9GXC8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3028</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92369">
        <property type="protein sequence ID" value="PRC92369"/>
        <property type="gene ID" value="S2091_3028"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="40" mass="4610" checksum="D1AAC9783F51D32F" modified="2018-07-18" version="1">MSVNKLLKTHPMKMASSKLKQYSINRLIVDRAASDKHLVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXK1</accession>
    <name>A0A2S9GXK1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_2830</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92455">
        <property type="protein sequence ID" value="PRC92455"/>
        <property type="gene ID" value="S2091_2830"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002549">
        <property type="entry name" value="AI-2E-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21716">
        <property type="entry name" value="PTHR21716"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01594">
        <property type="entry name" value="AI-2E_transport"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="38"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="63"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="96"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="186"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="250"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="289"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="315"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="350"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="9"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC92455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="395" mass="43442" checksum="40AB49501A44086A" modified="2018-07-18" version="1">MERLASISPPNDASETENTQAEEVHNKNFSPRTLRIHLLKHGWALTTVGIVAFVFALSFSQKFLIPLIFSIFIAYTLNPLVCALERLKLPRIVATSMLIGGIMLATGMHVNLLIAEFDSILVQLPAVTHRLSVELTNGRYGQATLIEKVQDAATELERATTEAAGNKVELRRLAPTDQSVIKLREWLFLGSMSLLGFLGQATMVLFLVFFLLLSGDMFKRKLVKLAGPTLHKKKITVLILNHINTSIQRYMFMLLVTNSLVGILSWIAFKIIGVDNAGAWALTSSFLHVIPYFGTVLIAVVTGLAAFMQFNSLSTAFMVAGVSLGITTFVGVFVTTWMTGRIAKMNPAGVFIALLFWGWLWGAWGLLLGIPIIVLVKVVSEHIEGMEAITELLGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXS6</accession>
    <name>A0A2S9GXS6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2897</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92522">
        <property type="protein sequence ID" value="PRC92522"/>
        <property type="gene ID" value="S2091_2897"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015665109" evidence="1">
        <location>
            <begin position="24"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="85" mass="9076" checksum="993B9B64564BDCE7" modified="2018-07-18" version="1">MKKIGIPIVFSALLLSLSGPSWSSDVTGESASAETAGHITGVGGVFFKAKDPKALATWYRDVLGLQLAVGEVLRCAMMRPSIRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXY3</accession>
    <name>A0A2S9GXY3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2639</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the N-Me-Phe pilin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92584">
        <property type="protein sequence ID" value="PRC92584"/>
        <property type="gene ID" value="S2091_2639"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009289">
        <property type="term" value="C:pilus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007155">
        <property type="term" value="P:cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010595">
        <property type="entry name" value="DUF1161"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001082">
        <property type="entry name" value="Pilin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06649">
        <property type="entry name" value="DUF1161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00114">
        <property type="entry name" value="Pilin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="267" mass="29873" checksum="0BD8FD82A1F47941" modified="2018-07-18" version="1">MTPHNRKPKNFFDSDMTYSIPRFSSNWMNARFFTLWIAALLGMSAVAYAEPTTNMEEQLSKFKRISYGLMEFSRYKVAVTEFFLVNAKFPSSNKQIGMPAAEKFRSDMIDSVNIESEGVIAINFLDFPTIPHAWIHLVPAVTETGQMHWHCVSNIPDIGRTAPDCDYDQNPLQTAVNSEADASIKATPALMSNLVIKSAIPEELNASASILSCAALQHTIEEKLLAKGIKNFKLNIVEKSHSSTAMNVGRCDGGKRKIIYLKNFRVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GY19</accession>
    <name>A0A2S9GY19_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Orotidine 5'-phosphate decarboxylase</fullName>
            <ecNumber evidence="7">4.1.1.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">OMP decarboxylase</fullName>
            <shortName evidence="7">OMPDCase</shortName>
            <shortName evidence="7">OMPdecase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">pyrF</name>
        <name evidence="9" type="ORF">S2091_2611</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>H(+) + orotidine 5'-phosphate = CO2 + UMP</text>
            <dbReference type="Rhea" id="RHEA:11596"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57538"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="EC" id="4.1.1.23"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; UMP from orotate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the OMP decarboxylase family. Type 2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.23" evidence="7"/>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92556">
        <property type="protein sequence ID" value="PRC92556"/>
        <property type="gene ID" value="S2091_2611"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00070">
        <property type="reaction ID" value="UER00120"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004590">
        <property type="term" value="F:orotidine-5'-phosphate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006207">
        <property type="term" value="P:'de novo' pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044205">
        <property type="term" value="P:'de novo' UMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01215">
        <property type="entry name" value="OMPdecase_type2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018089">
        <property type="entry name" value="OMPdecase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011995">
        <property type="entry name" value="OMPdecase_type-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001754">
        <property type="entry name" value="OMPdeCOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43375">
        <property type="entry name" value="PTHR43375"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00215">
        <property type="entry name" value="OMPdecase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00934">
        <property type="entry name" value="OMPdecase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="SSF51366"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02127">
        <property type="entry name" value="pyrF_sub2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00156">
        <property type="entry name" value="OMPDECASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="6 7" id="KW-0456">Lyase</keyword>
    <keyword evidence="5 7" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OMPdecase" evidence="8">
        <location>
            <begin position="19"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="7">
        <location>
            <position position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC92556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="273" mass="29773" checksum="FFA7F88BEBB9E0E5" modified="2018-07-18" version="1">MTTSYISKLTQAWQTNNSLLCVGLDPDLAKLPAQFQTQPDGIFEFCGAIIDATADLACSFKPQIAYFSALRAEPQLEAICAYLRENYPHLPIILDAKRGDIGATAEQYAREAFERYGADAVTVNPYMGFDSVAPYLEWQDKGCIVLCRTSNAGGSDLQFLQVNGRPLYQHVADLVANKWNRNGQCSLVVGATFPEEIKQVRHIVGEMPLLVPGIGAQGGDIAATVAAGKTATGGMMINSSRAILFAKTLDGEDFKQAARRVAQQTRDEINLYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GY31</accession>
    <name>A0A2S9GY31_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7">DNA repair protein RecO</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6 7">Recombination protein O</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">recO</name>
        <name evidence="10" type="ORF">S2091_2665</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Involved in DNA repair and RecF pathway recombination.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the RecO family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92610">
        <property type="protein sequence ID" value="PRC92610"/>
        <property type="gene ID" value="S2091_2665"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1440.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00201">
        <property type="entry name" value="RecO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037278">
        <property type="entry name" value="ARFGAP/RecO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022572">
        <property type="entry name" value="DNA_rep/recomb_RecO_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003717">
        <property type="entry name" value="RecO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042242">
        <property type="entry name" value="RecO_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33991">
        <property type="entry name" value="PTHR33991"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02565">
        <property type="entry name" value="RecO_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11967">
        <property type="entry name" value="RecO_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57863">
        <property type="entry name" value="SSF57863"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00613">
        <property type="entry name" value="reco"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="4 7" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="5 7" id="KW-0234">DNA repair</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA_rep/recomb_RecO_N" evidence="9">
        <location>
            <begin position="40"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00033409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF11967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC92610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="271" mass="30432" checksum="490D05DE04323BAD" modified="2018-07-18" version="1">MTDAVDTHLPDSFETLESAPPPMRTRLRSTPIPLRPLRVLTQPGFVLHSYPYKETSLIVDVFSRQYGRVALLAKGAKRPHSQLRGALQTFQPLTLSWSGKSELQTLTAAEWVGGMLPLEKNALLCGFYLNEIIIKLMQRDDPQPLLFDEYVTTINQLAHAEPAPIVLRKFELNLLKTAGVVSDLSFCTKQRSRVEPDILYIVDPEAGTRPAQERDGGTKVHGKTLLDMQAADYTDINTQLQSKFLMRSLLAHHLHGAPINTRQILMDLQNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GY56</accession>
    <name>A0A2S9GY56_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2712</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92657">
        <property type="protein sequence ID" value="PRC92657"/>
        <property type="gene ID" value="S2091_2712"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="114" mass="13062" checksum="CF72E02E3C42D136" modified="2018-07-18" version="1">MIKPKRIFDHETVLAFIQENAGTKYTGAVLARIFKVDPSEMRAMLQKMHSENLVESISGHCKYFFISKATVENLIFPTHRAHAFKPYVQPKNMGERCKELYPSGHSFIAMGRES</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GY99</accession>
    <name>A0A2S9GY99_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyl transferase family 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2435</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92705">
        <property type="protein sequence ID" value="PRC92705"/>
        <property type="gene ID" value="S2091_2435"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="2">
        <location>
            <begin position="5"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="396" mass="44384" checksum="6C8D539BA50713A6" modified="2018-07-18" version="1">MPILSIVVATHNRSNYAIFAAKSVLSIESELIELIIHDTSTDGRLVIDIEEITKDSRLHYHYCNVRLSMTENHNRALSLATGEYVCLIGDDDTVTSEILDAVQWAIENNVDAISPRVVANYAWPDFLSKTFGSGHSSRIYIDSFSSDISQMQSASGLNNSLRAACQGTDGLPKIYHGIVKRSVMEKVKEKTGNYFHGVSPDVSGALGIASMIDSFVLIDYPLTIPGAAGNSNTGRSAMNAHRGRLEDDPHIKPYKDLIWPPLIPRFFSVETVWSQAAYETLSRLYDGKLNEFNYIHLYSICLVNHPDYFNEIFNAIVVYKNQFKLNIIIVLLKIFFNAMSISIRKIIRLSKRALKPTAAGGRFFIPDVKNIFEASQILKNYLNSKSMSFKNRGKNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYC3</accession>
    <name>A0A2S9GYC3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyl transferase 4-like domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2441</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92711">
        <property type="protein sequence ID" value="PRC92711"/>
        <property type="gene ID" value="S2091_2441"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13579">
        <property type="entry name" value="Glyco_trans_4_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="105"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="2">
        <location>
            <begin position="16"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13579"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="422" mass="47536" checksum="99E4E35C554A630F" modified="2018-07-18" version="1">MRILIVTQYFWPENFRINDLASDFANKGHEVTVLTGSPNYPEGDLYPEFAADPGRFSKYQSVKILRIAHVLRGQSKVRLMLNYLTFFINASLTGAWKLRRSEFDVIFVFAVSPITMAIPAIVLGRLKHIPIFLWVQDLWPETLSAVGVVRSPFLLKMVGKMVSWIYAKCDHILIQSRAFTASVQQYCDQAHLPGKVLYFPNWAEQVFSQTSYHKQDVLKRDDELFTILFAGNIGDAQDFPAILNAAELLKSNERIRWVIVGDGRARDWVADEVVRRGLQSCVHLVGRFSLETMPSFFQVADALLVALKSDDIFSHTVPGKVQSYLAAGKAILGMIDGEARLVIDESGGGRSCASGASAELAQLVMEMSATSKEDLAQMGERGRQYYQRHFDRETLLKKLEMYFQAAKAGQIPLDNTVLYPHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYI7</accession>
    <name>A0A2S9GYI7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative HD phosphohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2503</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92773">
        <property type="protein sequence ID" value="PRC92773"/>
        <property type="gene ID" value="S2091_2503"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01966">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51831">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HD" evidence="1">
        <location>
            <begin position="27"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="186" mass="21045" checksum="EAA6F32A5EACE829" modified="2018-07-18" version="1">MTLSVQHITELFSNADTHLYGGEAITHQQHALQTAWMAEQANEDDALIIACLLHDLGHMLFGQGDEYLACGIDDRHEQKIVPFLSLLFPAEVLEPIRWHVDAKRYLCYADPYYQAALSEASKMSMELQGGVMNEADALCFFNRRYAQAALALRRYDDAAKVPNLVVPEFTHYFPRLLALTEKKSAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYM6</accession>
    <name>A0A2S9GYM6_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Probable transcriptional regulatory protein S2091_2554</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_2554</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the TACO1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92824">
        <property type="protein sequence ID" value="PRC92824"/>
        <property type="gene ID" value="S2091_2554"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.980">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00693">
        <property type="entry name" value="Transcrip_reg_TACO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017856">
        <property type="entry name" value="Integrase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002876">
        <property type="entry name" value="Transcrip_reg_TACO1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026564">
        <property type="entry name" value="Transcrip_reg_TACO1-like_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029072">
        <property type="entry name" value="YebC-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12532">
        <property type="entry name" value="PTHR12532"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01709">
        <property type="entry name" value="Transcrip_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75625">
        <property type="entry name" value="SSF75625"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01033">
        <property type="entry name" value="TIGR01033"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 4" id="KW-0805">Transcription regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC92824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="241" mass="26175" checksum="B9FEEE74B1ECC8D1" modified="2018-07-18" version="1">MAGHSKWANIKHKKAATDAKRGKVWTRIIKEITVAARMGGGDVGTNPRLRLAIEKAADSNMPKETVVRATQRGSGNLEGANYEEIRYEGYGINGAAIIVDCLTDNKVRTVAEVRHAFSKYGGNMGTEGSVAFMFKHCGQFFFAPGTNEDALMEAALNAGAEDIISDDEGGFEVVCPPYDFAAIKQSLEAAGFKADMAEIIMKPDTETLFEGENAIKMQKLLDALENLDDVQDVYTNAILEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYY7</accession>
    <name>A0A2S9GYY7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2325</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92908">
        <property type="protein sequence ID" value="PRC92908"/>
        <property type="gene ID" value="S2091_2325"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010718">
        <property type="entry name" value="DUF1294"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06961">
        <property type="entry name" value="DUF1294"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="103"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="138" mass="15303" checksum="C75FEA68C4AD5878" modified="2018-07-18" version="1">MHFNTGKKQRKANNGIFIGIVSVIFIFYLLGSFFTGHVQLIALCIYAAVSIISFIAYYADKNAAERGTWRIQENTLHMMALLGGWPGAYAAQRITRHKTIKEPFQSIFVVSVILNILGFILYSSPTASSAILGLMGRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZ65</accession>
    <name>A0A2S9GZ65_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">OmpA family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_2417</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC93000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93000">
        <property type="protein sequence ID" value="PRC93000"/>
        <property type="gene ID" value="S2091_2417"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07185">
        <property type="entry name" value="OmpA_C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006664">
        <property type="entry name" value="OMP_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006665">
        <property type="entry name" value="OmpA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036737">
        <property type="entry name" value="OmpA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00691">
        <property type="entry name" value="OmpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01021">
        <property type="entry name" value="OMPADOMAIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103088">
        <property type="entry name" value="SSF103088"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51123">
        <property type="entry name" value="OMPA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015654629" evidence="3">
        <location>
            <begin position="23"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="domain" description="OmpA-like" evidence="4">
        <location>
            <begin position="104"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC93000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="225" mass="23327" checksum="64B94EC01C587BF6" modified="2018-07-18" version="1">MNTLAKLVFAASAAVMAISASAQTTVTDTKAPTPYSAYVQDAQGNIVRDAFGLCIHTGYWTPADAIVVGCDGVEAPKPAPVVVAPPAPVAAPAPVVVAPPAPVPTTEKVTFAADALFDFDKSVLKPEGKAKLTELAANLKNVNLEAIVTTGHTDSVGKAEYNQKLSVRRAEAVKAYLVSSGVAADRIYTSGKGATQPVADNKTADGRAKNRRVEIEVVGTRTINK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZ72</accession>
    <name>A0A2S9GZ72_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Phosphoglycolate phosphatase, bacterial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_2415</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92998">
        <property type="protein sequence ID" value="PRC92998"/>
        <property type="gene ID" value="S2091_2415"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041492">
        <property type="entry name" value="HAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006346">
        <property type="entry name" value="PGPase/MupP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13419">
        <property type="entry name" value="HAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00413">
        <property type="entry name" value="HADHALOGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01549">
        <property type="entry name" value="HAD-SF-IA-v1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01509">
        <property type="entry name" value="HAD-SF-IA-v3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01449">
        <property type="entry name" value="PGP_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC92998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="219" mass="23654" checksum="DEC3F98CA0383E3D" modified="2018-07-18" version="1">MKSLGTIRAVLFDLDGTLADTAPDLAAAVNLMRTQRKLEPAPYAQLRPHASAGARGLLGAGFGVTPHDAEFDAMRIEFLNNYEAAICQHSSLFDGIAELLQTIIAHGIPWGIVTNKAARFTQPLVPLLGLQHASCVISGDTTAHSKPHPEPLLEAARQLQLAPQDCCYLGDDLRDIQAAQAAGMRSIAAAWGYCGQTEPEQWQADLLLYEPSELLKFII</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZG3</accession>
    <name>A0A2S9GZG3_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HicB-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2183</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93097">
        <property type="protein sequence ID" value="PRC93097"/>
        <property type="gene ID" value="S2091_2183"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1220.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013321">
        <property type="entry name" value="Arc_rbn_hlx_hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031807">
        <property type="entry name" value="HicB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010985">
        <property type="entry name" value="Ribbon_hlx_hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035069">
        <property type="entry name" value="TTHA1013/TTHA0281-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15919">
        <property type="entry name" value="HicB_lk_antitox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143100">
        <property type="entry name" value="SSF143100"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47598">
        <property type="entry name" value="SSF47598"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HicB-like" evidence="1">
        <location>
            <begin position="3"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF15919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="128" mass="13966" checksum="2B649F1E294DEAD9" modified="2018-07-18" version="1">MLYPIYVHLGDDTHAHSATFPDFPGCFSAADELNDLPAAVQEAVEAHFSDGEEVPAPSDVTTLAANPDYQGGLWMLFDIDLSKVSTKSMRLNITLPENLVHEIDAFAKAHHMTRSGFLAQAANKAMQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZR7</accession>
    <name>A0A2S9GZR7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Putative permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_1962</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the UPF0718 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93224">
        <property type="protein sequence ID" value="PRC93224"/>
        <property type="gene ID" value="S2091_1962"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005524">
        <property type="entry name" value="DUF318"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03773">
        <property type="entry name" value="ArsP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="75"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="114"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="147"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="173"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="230"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="263"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="289"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="327"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC93224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="350" mass="36711" checksum="561FD65B6F96C6D1" modified="2018-07-18" version="1">MNSTRPSSSALSWITFILIAVGGLFYVKWSPYYHRAFVAASNHAIGQSILMGTAASPPPPSLDAALNYAFAYGKAIWQAMVLGLLLGSGVQALLPPHWVTKALGGTGFGSVAAGGLLSIPGMMCTCCAAPVVAGLRARQASPGAAIAFWLGNTVLNPATLIFMGFVLGWNWSALRLALGLLMVFGLGYFANRIMTKEEIQSAETKFAPTDEAPLIGNVFTRWMKILAQMAIRLIPEYIILILLLGAARAFLFPHIGPEIGNHLGWILAFACAGALFVIPTAGEVPIIQAMLALGLGVGPAGALLMTLPPISIPSLAMLARSFKPRLLLIVTVTVVAFGVLAGLLAIGLGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZY1</accession>
    <name>A0A2S9GZY1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2033</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93295">
        <property type="protein sequence ID" value="PRC93295"/>
        <property type="gene ID" value="S2091_2033"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015596985" evidence="1">
        <location>
            <begin position="24"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="141" mass="13636" checksum="C3771EA506985BA1" modified="2018-07-18" version="1">MKLVKQGMLAALLCLSLSLNAQAADCISCAPSQGSAGLSAGSGLVLVGSMSVVAASGMIVVESVVVGADGIVIVVKGISNGVSATIKLSGQAAQGISLAAGTVINTSAMATGYLLVASGTVLAFIPNEIGQALIHHSKVGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZY8</accession>
    <name>A0A2S9GZY8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2029</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93291">
        <property type="protein sequence ID" value="PRC93291"/>
        <property type="gene ID" value="S2091_2029"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="108" mass="12112" checksum="AEB042C28B16180A" modified="2018-07-18" version="1">MTEPLFFQHHVFFCVNQRDDGRASCADCGALASQKYAKQRIKELNLSGPGKIRINQAGCLDRCDAGPVLVVYPEGTWYTFVDNHDIDEIIDSHLVHGKIVQRLLIDPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H002</accession>
    <name>A0A2S9H002_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Peptidase family S41</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2018</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93280">
        <property type="protein sequence ID" value="PRC93280"/>
        <property type="gene ID" value="S2091_2018"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005151">
        <property type="entry name" value="Tail-specific_protease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03572">
        <property type="entry name" value="Peptidase_S41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TSPc" evidence="1">
        <location>
            <begin position="5"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="102" mass="11356" checksum="D11D82F1B443466B" modified="2018-07-18" version="1">MRRGAWRGHVYVLVDNKTTSSVEMFASQMKDSGIAKIVGSQSGGTGCGFMAEGKPLELPNSKLRFWIPNCARLRSDMVINSTIFLKHSLGYQSIFKSYTAYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H055</accession>
    <name>A0A2S9H055_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">8-amino-7-oxononanoate synthase</fullName>
            <shortName evidence="6">AONS</shortName>
            <ecNumber evidence="6">2.3.1.47</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">7-keto-8-amino-pelargonic acid synthase</fullName>
            <shortName evidence="6">7-KAP synthase</shortName>
            <shortName evidence="6">KAPA synthase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">8-amino-7-ketopelargonate synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">bioF</name>
        <name evidence="9" type="ORF">S2091_2071</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>6-carboxyhexanoyl-[ACP] + H(+) + L-alanine = (8S)-8-amino-7-oxononanoate + CO2 + holo-[ACP]</text>
            <dbReference type="Rhea" id="RHEA:42288"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="Rhea" id="RHEA-COMP:9955"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78846"/>
            <dbReference type="ChEBI" id="CHEBI:149468"/>
            <dbReference type="EC" id="2.3.1.47"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 6 7">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 6">Cofactor biosynthesis; biotin biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 6">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.47" evidence="6"/>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93333">
        <property type="protein sequence ID" value="PRC93333"/>
        <property type="gene ID" value="S2091_2071"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00078"/>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008710">
        <property type="term" value="F:8-amino-7-oxononanoate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009102">
        <property type="term" value="P:biotin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01693">
        <property type="entry name" value="BioF_aminotrans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004723">
        <property type="entry name" value="AONS_Archaea/Proteobacteria"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022834">
        <property type="entry name" value="AONS_Proteobacteria"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00858">
        <property type="entry name" value="bioF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0093">Biotin biosynthesis</keyword>
    <keyword evidence="6 7" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="8">
        <location>
            <begin position="39"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Pyridoxal phosphate binding" evidence="6">
        <location>
            <begin position="110"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="19"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="138"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="184"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="212"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="239"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="360"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="6 7">
        <location>
            <position position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR604723-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC93333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="396" mass="42142" checksum="5D4B5922BC085C8F" modified="2018-07-18" version="1">MIEQIEQRLAELDKQDLLRHRRVTATPCAAVMNVDGRTMLAFCSNDYLGLAAHPQIQHALQEGVTLYGAGSGASHLISGHSKAHAQLEERLAAMQSPYLEQARALYLSTGYMANLAVLSGLAATDPGQAEIFSENLNHASLIDGAKLARCKVQVYPHADLIALENLLQQSGASTKIVVTDSVFSMDGVIAPLPEILALCERYNAWLVIDDAHGFGVLGDGAGILSHFNLRSKNIVYMGTLGKAAGVSGAFIAAHGSVIEWLVQKARPYIYTTAAPPALAHALLTSLDIICGAEGAQRRTHLQGLIKQFKTAIGSEVGGMSLLASDTQIQPLIVGENHLAMQLAARLYERGIWVPAIRPPTVPVGTARLRVTLSAAHSSAQVATLLSELDGLQKKAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H079</accession>
    <name>A0A2S9H079_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="12">TonB family C-terminal domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">S2091_1776</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
            <orientation evidence="1">Periplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TonB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93389">
        <property type="protein sequence ID" value="PRC93389"/>
        <property type="gene ID" value="S2091_1776"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006260">
        <property type="entry name" value="TonB/TolA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037682">
        <property type="entry name" value="TonB_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03544">
        <property type="entry name" value="TonB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01352">
        <property type="entry name" value="tonB_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="14"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_C" evidence="11">
        <location>
            <begin position="139"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="54"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF03544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PRC93389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="218" mass="23218" checksum="83752B3B33D53DCF" modified="2018-07-18" version="1">MDFSEHGQDPTKKLVGISVVVLIHVIVIYALLNGLGKQIIAVIKDIPIETKVIEEVKPPPPPPDAPPPPPKLAAPPPPFIPPPEVQVAQQPVVNTISAVSNVQPPRQDFTKAVAAPPVVAKASGPSVVAAVVDFSTCDKPDYPRNSVRNEEHGTVRIAFLIGLDGRVADSKIEKSSGFRALDAAAKNGLSLCKFKPGTVDGKPQQTWTAVDYVWTLPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H090</accession>
    <name>A0A2S9H090_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">D-galactonate dehydratase</fullName>
            <shortName evidence="1">GalD</shortName>
            <ecNumber evidence="1">4.2.1.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">dgoD</name>
        <name evidence="3" type="ORF">S2091_1789</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the dehydration of D-galactonate to 2-keto-3-deoxy-D-galactonate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>D-galactonate = 2-dehydro-3-deoxy-D-galactonate + H2O</text>
            <dbReference type="Rhea" id="RHEA:18649"/>
            <dbReference type="ChEBI" id="CHEBI:12931"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:57989"/>
            <dbReference type="EC" id="4.2.1.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="1">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Carbohydrate acid metabolism; D-galactonate degradation; D-glyceraldehyde 3-phosphate and pyruvate from D-galactonate: step 1/3.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="1">Reaction proceeds via an anti dehydration.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the mandelate racemase/muconate lactonizing enzyme family. GalD subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.6" evidence="1"/>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93402">
        <property type="protein sequence ID" value="PRC93402"/>
        <property type="gene ID" value="S2091_1789"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00081">
        <property type="reaction ID" value="UER00518"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008869">
        <property type="term" value="F:galactonate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009063">
        <property type="term" value="P:cellular amino acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034194">
        <property type="term" value="P:D-galactonate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03325">
        <property type="entry name" value="D-galactonate_dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01289">
        <property type="entry name" value="Galacton_dehydrat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036849">
        <property type="entry name" value="Enolase-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029017">
        <property type="entry name" value="Enolase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029065">
        <property type="entry name" value="Enolase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023592">
        <property type="entry name" value="Galactonate_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018110">
        <property type="entry name" value="Mandel_Rmase/mucon_lact_enz_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013342">
        <property type="entry name" value="Mandelate_racemase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034593">
        <property type="entry name" value="Mandelate_racemase_DgoD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013341">
        <property type="entry name" value="Mandelate_racemase_N_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48080">
        <property type="entry name" value="PTHR48080"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13378">
        <property type="entry name" value="MR_MLE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02746">
        <property type="entry name" value="MR_MLE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00003">
        <property type="entry name" value="D-galactonate_dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00922">
        <property type="entry name" value="MR_MLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51604">
        <property type="entry name" value="SSF51604"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54826">
        <property type="entry name" value="SSF54826"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00908">
        <property type="entry name" value="MR_MLE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00909">
        <property type="entry name" value="MR_MLE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0456">Lyase</keyword>
    <keyword evidence="1" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MR_MLE" evidence="2">
        <location>
            <begin position="190"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="1">
        <location>
            <position position="250"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="1">
        <location>
            <position position="350"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="248"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="274"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="300"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="site" description="Increases basicity of active site His" evidence="1">
        <location>
            <position position="323"/>
        </location>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="1">
        <location>
            <position position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="447" mass="49723" checksum="4CD8107763059EDF" modified="2018-07-18" version="1">MVIINLFNVDIFRQRLRSGMVTDADAEFGTVHVFHFHMGIHELFIFAVQLIRLHSCWSLEHLTASMKITKLTTYRIAPRWMLLKIDTDAGIVGWGEPIIEGRARTVEMAVQEMQPYLIGQDPARINDLWHAMYRGGFYRGGSILMSAIAGIDQALWDIKGKVHGVPVYQLLGGLVRDRMKTYSWVGGDRPSDVIAGITSLRNAGFDTFKLNGTEELGMIDSAMAIDAAVERIAEIRAAFGSTIEFGIDFHGRVSAPMAKVLLRELEPYRPLFVEEPVLAEQAEYYPRLANSTSIPLAAGERMYSRFDFKNVFHQGGLSIVQPDLSHAGGITECCKIAAMAEAYEIALAPHCPLGPIALAACLQVDFVSHNAVLQEQSIGIHYNQGAELLDYVINREDFKITNGYIAPFPKPGLGVEIDEERVIAASLNPPDWRNPLWRHADGSVAEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0D6</accession>
    <name>A0A2S9H0D6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1832</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93445">
        <property type="protein sequence ID" value="PRC93445"/>
        <property type="gene ID" value="S2091_1832"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045459">
        <property type="entry name" value="DUF5908"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19265">
        <property type="entry name" value="DUF5908"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="54" mass="6380" checksum="868AB85A051C382C" modified="2018-07-18" version="1">MAIEIKELIIKTTIVNRPINKDDSSHIDKDSVKDEILSECKKMVQTLLRERRER</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0D8</accession>
    <name>A0A2S9H0D8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1828</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93441">
        <property type="protein sequence ID" value="PRC93441"/>
        <property type="gene ID" value="S2091_1828"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="266" mass="30364" checksum="95127C963B8AFE0D" modified="2018-07-18" version="1">MGRYIPLLSIQIQHEFFEGCSESNNLVLRFLPSETSSEIIQRENLLLRQCANGIEVWQEENNTQSTVPSTVELNLTFLVSSSDPHFNFYTDWHLAKPINFINQTPVDSSNVVHLTAQTVEEQDFGLSSFEKKKNPTLFTVQLQHQISTEVTHYLVELKARAMHWKYYFFGALAKKKLQIVDLDEKKAEGCRFTPSENVVTSTSVAFISEIALPMRSMPTQRFQLREEGAAGRVLMRRLPSASINKIGKERDPNGQSLVVAEIYIHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0M0</accession>
    <name>A0A2S9H0M0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Stp1: sugar transferase, PEP-CTERM/EpsH1 system associated</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1921</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93534">
        <property type="protein sequence ID" value="PRC93534"/>
        <property type="gene ID" value="S2091_1921"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017521">
        <property type="entry name" value="Sugar_tfrase_PEP-CTERM_Stp1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03087">
        <property type="entry name" value="stp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="416" mass="47161" checksum="1A5323BC8F0B1E0E" modified="2018-07-18" version="1">MTKPAKENLLLLVHRIPFPPNKGDKIRSFHLLKHLLLNYQVHLGCFIDDDNDRQYVNTVKEMCGESYFGALHPLKAKVRSLGALLSNRPLSLDYYRDKQMQEWVDATLSKHQIQRVVVFSSAMAQFIEHVTQARRVIDFVDVDSDKWLQYAGKKIWPMSWLYQREGTQLLNYERRVARECDVSLFVSETEANLFKRLAPESSAKIDFFNNGVDTDYFSPELTHANPYNAGQQVIVFTGAMDYWPNIDAVQWFAQEVLPLIRERNPTACFYIVGTRPSDAVKNLTRQPGVHVTGSVPDVRPYLAHARVVVAPLRIARGIQNKVLEAMAMAKTVLVSAQALEGIEAELGRDLLMAQNAAQFAGYACLVLDGKQEELGSAARAKVLARYNWTANLSRVDALLDPDRSESSNINSQEQRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0Q4</accession>
    <name>A0A2S9H0Q4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1560</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93559">
        <property type="protein sequence ID" value="PRC93559"/>
        <property type="gene ID" value="S2091_1560"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="83"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="112"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="133"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="175"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="204"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="271"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="300"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="325"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="350"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="517" mass="58949" checksum="F7300276CC7E7D0B" modified="2018-07-18" version="1">MYLTTNNKHALFLTLALATFIVSTIFIWQGNKGFSLWDEGFLWYGAQRTMLGEVPIRDFLAYDPGRYYWSATLMSIFGNNGIISLRVTVAIFQTFGLFIGLFLISISTKKQNLIYLLLSCAVLFIWMLPRHKLFDISLSIFIIGILTFLIENPTNKRFFITGFCIGLIAFFGRNHGLYAVLGMIGVMLWLNIKKNQNINFLKNFLVWITGVIIGFSPMILMIVFVPGFALAFLDSIRFLFEIKATNLPLPIPWPWLIQFNTLPFNESIRGFLVGIIFIGVLVFGVLSIAWVFLGKIKNKQIPSAFVATSFLALPYAQFAYSRADVSHLAQGIFPFLIGGLVLLSSQPSKIKWSITIMFCIGSVWILLAYQPDWQCIENKQCVEIKISNNKLEVDPSTANDVALLRKLVNQYAPNNESFIAAPFWPGAYALLDRKSPMWEIYALFPRSQAFEQTEIERIKKTNPRFAIVLDIPLDGHNELRFKNTHPLIHQYIVDNFDLIPNSLNQTYQIYKSKEGSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H125</accession>
    <name>A0A2S9H125_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1669</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93668">
        <property type="protein sequence ID" value="PRC93668"/>
        <property type="gene ID" value="S2091_1669"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="23"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="61"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="239" mass="26541" checksum="7903D005AA28DEDC" modified="2018-07-18" version="1">MKNNSSRYKTISTIKVVEDKNTWLRFAMIVLVLLGLFAAFSFFTYQLGGTISGTAPAKEQLSELKQRVEKLDSEREQLSSTANSADSELNIERATQKQLATQVQALTAENNKLKEDLAFFENLIPAAKGQEGIRIGAFKADASNRLQVQYRILVMQGGKSVPDFVGELQFTATVLQGGKTVTLTFPEAKEGDAGKLKLSFKYYQRMEGTLTLPEGAIIKTLQARILDKGQLRTYQSINF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H154</accession>
    <name>A0A2S9H154_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Efflux transporter, RND family, MFP subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_1710</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93709">
        <property type="protein sequence ID" value="PRC93709"/>
        <property type="gene ID" value="S2091_1710"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006143">
        <property type="entry name" value="RND_pump_MFP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01730">
        <property type="entry name" value="RND_mfp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="14"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="domain" description="HlyD_D23" evidence="4">
        <location>
            <begin position="82"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="132"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC93709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="389" mass="41305" checksum="9CA02353C1CDE977" modified="2018-07-18" version="1">MQIKHSASTTPKKTLAITVIVILAIAASFYFGISRSNENKKTVEADVPMFTVQADKLLVPPESPLRKRLVVAAVSSASPVHSIDIPGVVEADPANTVNILPPLSGRLIELKVKLGDAVKAGQVVAIISSSDLAQAYSDADKARDALDLAQRALQRGEGVNSAGANAAKDLEQIKSNHNQAQAEFNRAEQRLKTLGVANDSNRDSKNRVLTISTPISGTVTVLNNGAGSYINDATASIMTVANLDHVWVTANVPESLVSTLHKGQNAEITLAAYAGETWQGKISTISAILEPDTHRNKARIIFSNTDGRLKPNMYANVKLATAQAGKLMIPTSALLMNNDSITVFVETTPWTFVRRTVSIGSEDGDQVSVLSGLAAGERVIVRGGVLIND</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1C6</accession>
    <name>A0A2S9H1C6_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5 7">30S ribosomal protein S9</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpsI</name>
        <name evidence="8" type="ORF">S2091_1667</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the universal ribosomal protein uS9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93666">
        <property type="protein sequence ID" value="PRC93666"/>
        <property type="gene ID" value="S2091_1667"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00532_B">
        <property type="entry name" value="Ribosomal_S9_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000754">
        <property type="entry name" value="Ribosomal_S9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023035">
        <property type="entry name" value="Ribosomal_S9_bac/plastid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020574">
        <property type="entry name" value="Ribosomal_S9_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21569">
        <property type="entry name" value="PTHR21569"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00380">
        <property type="entry name" value="Ribosomal_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00360">
        <property type="entry name" value="RIBOSOMAL_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016789"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC93666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="130" mass="14417" checksum="4F4886F5728CA104" modified="2018-07-18" version="1">MIGNFNYGTGRRKSAVARVFLKSGSGKIVVNGKPANEYFSRETGLMVIRQPLELTNHLETFDIMINVHGGGESGQAGAVRHGITRALIDYEATLKPELSKAGFVTRDAREVERKKVGLRKARRAKQFSKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1H5</accession>
    <name>A0A2S9H1H5_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">HPr kinase/phosphorylase</fullName>
            <shortName evidence="10">HPrK/P</shortName>
            <ecNumber evidence="10">2.7.11.-</ecNumber>
            <ecNumber evidence="10">2.7.4.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">HPr(Ser) kinase/phosphorylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">hprK</name>
        <name evidence="13" type="ORF">S2091_1402</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>[HPr protein]-L-serine + ATP = [HPr protein]-O-phospho-L-serine + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46600"/>
            <dbReference type="Rhea" id="RHEA-COMP:11602"/>
            <dbReference type="Rhea" id="RHEA-COMP:11603"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 10">
            <text>[HPr protein]-O-phospho-L-serine + H(+) + phosphate = [HPr protein]-L-serine + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:46604"/>
            <dbReference type="Rhea" id="RHEA-COMP:11602"/>
            <dbReference type="Rhea" id="RHEA-COMP:11603"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="10">Homohexamer.</text>
    </comment>
    <comment type="domain">
        <text evidence="10">The Walker A ATP-binding motif also binds Pi and PPi.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="10">Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the HPrK/P family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.-" evidence="10"/>
    <dbReference type="EC" id="2.7.4.-" evidence="10"/>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93793">
        <property type="protein sequence ID" value="PRC93793"/>
        <property type="gene ID" value="S2091_1402"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004712">
        <property type="term" value="F:protein serine/threonine/tyrosine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006109">
        <property type="term" value="P:regulation of carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01918">
        <property type="entry name" value="HprK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1390.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01249">
        <property type="entry name" value="HPr_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003755">
        <property type="entry name" value="HPr(Ser)_kin/Pase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011104">
        <property type="entry name" value="Hpr_kin/Pase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011126">
        <property type="entry name" value="Hpr_kin/Pase_Hpr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028979">
        <property type="entry name" value="Ser_kin/Pase_Hpr-like_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30305:SF1">
        <property type="entry name" value="PTHR30305:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07475">
        <property type="entry name" value="Hpr_kinase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02603">
        <property type="entry name" value="Hpr_kinase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75138">
        <property type="entry name" value="SSF75138"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00679">
        <property type="entry name" value="hpr-ser"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 10 13" id="KW-0418">Kinase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 10" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="6 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="5 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Hpr_kinase_N" evidence="11">
        <location>
            <begin position="43"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="domain" description="Hpr_kinase_C" evidence="12">
        <location>
            <begin position="135"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Important for the catalytic mechanism of both phosphorylation and dephosphorylation" evidence="10">
        <location>
            <begin position="206"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Important for the catalytic mechanism of dephosphorylation" evidence="10">
        <location>
            <begin position="270"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="active site" evidence="10">
        <location>
            <position position="143"/>
        </location>
    </feature>
    <feature type="active site" evidence="10">
        <location>
            <position position="164"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; for phosphorylation activity. Proton donor; for dephosphorylation activity" evidence="10">
        <location>
            <position position="182"/>
        </location>
    </feature>
    <feature type="active site" evidence="10">
        <location>
            <position position="249"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="158"/>
            <end position="165"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="165"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="207"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF07475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PRC93793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="314" mass="34551" checksum="D8D3041CD408C681" modified="2018-07-18" version="1">MPNPSTLSIQNIYEDNRDLLKLGWFAGCSGGDKLIFGDATSAADQVGHLNLIHPGRIQVMGHQEKAYYERISSNTRAHLFRDLVAGGTPAIIISQGLETPVDLMAVCDENNIPLFSTPLPSAQVIDFLRVFLSKRLAQQITMHGVFMDVLGVGVLITGDSGLGKSELGLELISRSHGLVADDAVEFSRIAPNMIEGRCPPLLQNLLEVRGLGLLDIRTIFGETAVRRKMRLKLIVHLVRRSALEENFERLPIDAQTEDVLGLAVRKVTIPVAAGRNIAVLLEAAVRNTILQLRGIDTLQEFMERQRKAMSDDED</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1K1</accession>
    <name>A0A2S9H1K1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1470</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93861">
        <property type="protein sequence ID" value="PRC93861"/>
        <property type="gene ID" value="S2091_1470"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="27"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="160" mass="19319" checksum="6F4E5618FB50247D" modified="2018-07-18" version="1">MLARSWRRWLLLLRKYQALLHHSQQRLQVGERRLTHVRQRLAAMEQECDRLQGEIGVQEQLAHAVGLDGAALGRQQLFDWLRKSAADRRRSQALRLELRRQQELCNECTYQVSEQHAHCLRLEQRRERYRTLLDGERKKVRLRQLEIEECEIEERVSWSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1P0</accession>
    <name>A0A2S9H1P0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1501</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93892">
        <property type="protein sequence ID" value="PRC93892"/>
        <property type="gene ID" value="S2091_1501"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032874">
        <property type="entry name" value="DDE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13610">
        <property type="entry name" value="DDE_Tnp_IS240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_Tnp_IS240" evidence="2">
        <location>
            <begin position="103"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="186"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="265" mass="31472" checksum="B68CE012F18D2681" modified="2018-07-18" version="1">MILIRQEIRWERGTVRLTKVSLVGLLCGMNPSKPLYFRHRFPSEIISHCVWLYFRFSLSYRDIEEMMAERGVVVTYGTIRNWSKKFDGIYAKRMRSRSKKANDQWHLDEVYLSINGKTHYLWRAVDQDGEVLDILVQPRRNKRAAKKFFQKLLKRLQYVPRLIITDKLGSYATAKAEIMPQIKHIQSKGANNRAENSHQPTRERERRMRRFKSPGHAQRFLATYGVIASFFRPGRHLLSAKNYCEIMHRRFTEWSEIVDSGYITQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1P7</accession>
    <name>A0A2S9H1P7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1497</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93888">
        <property type="protein sequence ID" value="PRC93888"/>
        <property type="gene ID" value="S2091_1497"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="82" mass="9196" checksum="C5B797DBD94C5207" modified="2018-07-18" version="1">MIKNDLFSKASVGFLLFSVPLTWKNSENTRYTDNMSCDFLGCLAVLRIFGKYIYSDVRSECSADCKQLMIGDFDGGGWLAYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2D2</accession>
    <name>A0A2S9H2D2_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 11">DNA-directed RNA polymerase subunit alpha</fullName>
            <shortName evidence="11">RNAP subunit alpha</shortName>
            <ecNumber evidence="2 11">2.7.7.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10 11">RNA polymerase subunit alpha</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9 11">Transcriptase subunit alpha</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">rpoA</name>
        <name evidence="13" type="ORF">S2091_1290</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 11">
            <text>a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="11">Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.</text>
    </comment>
    <comment type="domain">
        <text evidence="11">The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 11">Belongs to the RNA polymerase alpha chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="2 11"/>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94117">
        <property type="protein sequence ID" value="PRC94117"/>
        <property type="gene ID" value="S2091_1290"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed 5'-3' RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.120.12">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00059">
        <property type="entry name" value="RNApol_bact_RpoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011262">
        <property type="entry name" value="DNA-dir_RNA_pol_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011263">
        <property type="entry name" value="DNA-dir_RNA_pol_RpoA/D/Rpb3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011773">
        <property type="entry name" value="DNA-dir_RpoA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036603">
        <property type="entry name" value="RBP11-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011260">
        <property type="entry name" value="RNAP_asu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036643">
        <property type="entry name" value="RNApol_insert_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32108">
        <property type="entry name" value="PTHR32108"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01000">
        <property type="entry name" value="RNA_pol_A_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03118">
        <property type="entry name" value="RNA_pol_A_CTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01193">
        <property type="entry name" value="RNA_pol_L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00662">
        <property type="entry name" value="RPOLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55257">
        <property type="entry name" value="SSF55257"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56553">
        <property type="entry name" value="SSF56553"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02027">
        <property type="entry name" value="rpoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 11 13" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="6 11" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 11" id="KW-0804">Transcription</keyword>
    <keyword evidence="5 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RPOLD" evidence="12">
        <location>
            <begin position="20"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Alpha N-terminal domain (alpha-NTD)" evidence="11">
        <location>
            <begin position="1"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Alpha C-terminal domain (alpha-CTD)" evidence="11">
        <location>
            <begin position="246"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00024550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00032524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00033070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PRC94117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="325" mass="35707" checksum="8DD77A07B5A9F85A" modified="2018-07-18" version="1">MQNSLLKPRIIDVEMLAAGHAKVVMEPFERGYGHTLGNALRRVLLSSMVGYAPTEVTIAGVVHEYSTLDGVQEDVVDILLNLKGIVFKLHNRDEVTLTLKKDGEGAVLASDIDLPHDVELINPDHVIANLTAGGKLDMQIKVEKGRGYVPGNVRRLSEDANRTIGRIILDASFSPVRRVSYSVESARVEQRTDLDKLIINIETNGVITPEEAIRQSARVLVDQLNVFAALEGTEAAAEAPSRAPMVDPILLRPVDDLELTVRSANCLKAENIYYIGDLIQRTENELLKTPNLGRKSLNEIKEVLASRGLSLGMKLENWPPAGLEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2G2</accession>
    <name>A0A2S9H2G2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Amidohydrolases: amidohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1348</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94175">
        <property type="protein sequence ID" value="PRC94175"/>
        <property type="gene ID" value="S2091_1348"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017439">
        <property type="entry name" value="Amidohydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11014">
        <property type="entry name" value="PTHR11014"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005962">
        <property type="entry name" value="Pept_M20D_amidohydro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="SSF55031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01891">
        <property type="entry name" value="amidohydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="M20_dimer" evidence="2">
        <location>
            <begin position="185"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="395" mass="42930" checksum="8525CD6B0758C4FD" modified="2018-07-18" version="1">MNLIDPIVQFSAEIQQIRRDIHAHPELCYQEQRTADVVADKLTEWGIPVLRGMGVTGVVGIIKRGTSERAVGLRADMDALPMQELNTFAHTSKHAGKMHACGHDGHTAMLLGAAHYLAQHGTFDGTVYVIFQPAEEGGAGAKRMIEDGLFVQCPMEAVFGMHNWPGIPLGHFGVKDGPMMASSNEFEVTINGKGAHAAQPHKGIDPIMVAVQIAQSWQTIVSRNVSPVDSAVLSITQIHSGSATNVIPDQATLIGTVRTFKESVLDQVETNMQRIAEHTAKGFEAQVEFNFKRNYPALLNHPKETAIAADVLRSIVGNSAVNTQIEPTMGAEDFAYMLQAKPGCYVFIGNGDGDHREHGHGLGPCNLHNASYDFNDQLLPIGATYWVRLAEHFLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2I0</accession>
    <name>A0A2S9H2I0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transglycosylase SLT domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0816</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94195">
        <property type="protein sequence ID" value="PRC94195"/>
        <property type="gene ID" value="S2091_0816"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023346">
        <property type="entry name" value="Lysozyme-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008939">
        <property type="entry name" value="Lytic_TGlycosylase_superhlx_U"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008258">
        <property type="entry name" value="Transglycosylase_SLT_dom_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01464">
        <property type="entry name" value="SLT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48435">
        <property type="entry name" value="SSF48435"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53955">
        <property type="entry name" value="SSF53955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="SLT" evidence="2">
        <location>
            <begin position="514"/>
            <end position="621"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="683" mass="75423" checksum="52827BBDAEBFF121" modified="2018-07-18" version="1">MLSSESLNNLLMLKSLLFLKLLHTETPHAFLPLAHMPKLNICTKILVSSLTMLIISTSFAALGAELSGDDQRFLALRDAASKEDGARAVTLASQLSSYPLASYVDYYQLKARLRSANESEITDFLTRYNGSAIADRLRNDWLILLGRQSNWAMFDVQYPQFVLNDDTQLKCYALLSKLKQGQNVANDARNLLTSAKVYGEGCYPLFSNLVQSEQFSSADMWAQIRWAAEANSTAVAIQLATLVNLDKTAKALDKTGSKLEAEFSRPLAKTADAHETALILLGRLAKADPDKAVAALAKINRSLTDSERAVAWAQIALPSSQKLLPEAADYWKKGDDAALSLDGYQWRVRTALRNTDWSRVKTGIEAMPPSLLSESAWTYWLGRAYMAENKPALAQPLFQSIVNQTNFYGQLALEESGLQITIPATTPVLPADLAALSSNAGLQQSLQFFGMNLRFEGTREWNWQLRKMSERQLLAAAEFARQNDLLDRMVSTSDRTKTIVDFNQRFPTPHKDVISKTSDELGLDMAWVYGLIRQESRFILAAKSSAGASGLMQVMPGTARYVAKKRKIDNFDATKVNDIDTNIVLGTHYLSIVLANLNGSQVLASAGYNAGPNRSRAWRASLPKTVEGAIFAETIPYPETRDYVKNVLSNATYYAALFQQTPQSLKARLGSISPAPDDLTPSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2L3</accession>
    <name>A0A2S9H2L3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acetyltransferase (GNAT) family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0845</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94224">
        <property type="protein sequence ID" value="PRC94224"/>
        <property type="gene ID" value="S2091_0845"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032962">
        <property type="entry name" value="HPA2/HPA3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10545:SF42">
        <property type="entry name" value="PTHR10545:SF42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="11"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="156" mass="17747" checksum="FD29F0D51ED2A66D" modified="2018-07-18" version="1">MISENKILSPITIRPIEPSDFVAWKPLWDGYNAFYGRQNETALPAEVTEVIWQRFFDPIEPVFALVAELDGKLVGLSHYLYHRSTTKIEMVCYLQDLFTDPSVRGRGVGRSLIQGVTETARSAGINRVYWHTHESNSAARLLYDQVAKHTGFIVYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2P3</accession>
    <name>A0A2S9H2P3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0870</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94249">
        <property type="protein sequence ID" value="PRC94249"/>
        <property type="gene ID" value="S2091_0870"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="153" mass="17227" checksum="13B08F70CFA35CF5" modified="2018-07-18" version="1">MNTAHQNWFAGLKSLSQSDFPKKCACCGRVYQSEEDYFQETKAIRNAHTGLKVAQDDDDGLLVELFRNCVCGSTLLAFFSDRRDQSDAGNIRRKLFDEVLDYIVQTGVAPITARTELLRVIHGEQSDMLELWHAKILAAEKNGGLMTLIKSQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2Q7</accession>
    <name>A0A2S9H2Q7_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">30S ribosomal protein S7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rpsG</name>
        <name evidence="11" type="ORF">S2091_1319</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7 8">Belongs to the universal ribosomal protein uS7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94146">
        <property type="protein sequence ID" value="PRC94146"/>
        <property type="gene ID" value="S2091_1319"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.455.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00480_B">
        <property type="entry name" value="Ribosomal_S7_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000235">
        <property type="entry name" value="Ribosomal_S5/S7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005717">
        <property type="entry name" value="Ribosomal_S7_bac/org-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020606">
        <property type="entry name" value="Ribosomal_S7_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023798">
        <property type="entry name" value="Ribosomal_S7_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036823">
        <property type="entry name" value="Ribosomal_S7_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11205">
        <property type="entry name" value="PTHR11205"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00177">
        <property type="entry name" value="Ribosomal_S7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002122">
        <property type="entry name" value="RPS7p_RPS7a_RPS5e_RPS7o"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47973">
        <property type="entry name" value="SSF47973"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01029">
        <property type="entry name" value="rpsG_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00052">
        <property type="entry name" value="RIBOSOMAL_S7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7 8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 7 8" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4 7 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 7 9" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="2 7" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_S7" evidence="10">
        <location>
            <begin position="1"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003620"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC94146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="156" mass="17483" checksum="CC5ADB1BD729C7FE" modified="2018-07-18" version="1">MPRRREVPKRDILPDPKFGNVEVAKFVNVLMLSGKKSVAEGIIYGAFDHIQTKSGKDPLEVFAAAIGNCKPLVEVKSRRVGGANYQVPVEVRPVRRLALSMRWLREAANKRSEKSMPQRLGGELLEAAEGRGGAMKKRDEVHRMAEANKAFSHFRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2U4</accession>
    <name>A0A2S9H2U4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phenylacetate-CoA oxygenase, PaaJ subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0898</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94277">
        <property type="protein sequence ID" value="PRC94277"/>
        <property type="gene ID" value="S2091_0898"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034904">
        <property type="entry name" value="FSCA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002744">
        <property type="entry name" value="MIP18-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011883">
        <property type="entry name" value="PA_CoA_Oase4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01883">
        <property type="entry name" value="FeS_assembly_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117916">
        <property type="entry name" value="SSF117916"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02159">
        <property type="entry name" value="PA_CoA_Oxy4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FeS_assembly_P" evidence="1">
        <location>
            <begin position="9"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="168" mass="18580" checksum="09AC236B9E08F0A8" modified="2018-07-18" version="1">MVNQQASTERIWEWLSGIPDPEMPFLSIVDLGIVRDVHWEEEQLRIVVTPTYSGCPAKSHIDASIRNTLLDRGIEHLALETRLSPAWSTDWLGDVAKAKLLAAGIAPPMASEVPMRKLEYRAWSIATPSCPLCGSASTTVRGEFGSTLCKSLYVCGDCANPFEHFKCF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2V1</accession>
    <name>A0A2S9H2V1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Bacterial regulatory protein, tetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0919</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94298">
        <property type="protein sequence ID" value="PRC94298"/>
        <property type="gene ID" value="S2091_0919"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041669">
        <property type="entry name" value="TetR_C_15"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17918">
        <property type="entry name" value="TetR_C_15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="11"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="34"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="197" mass="21680" checksum="1A18FD5E76F0DC49" modified="2018-07-18" version="1">MRKAPSQQRSQIMVDTIIEAATRVLALRGWARFKTSEVADVAGVSIGSLYQYFPNKLGLAEEIRQRHLDAVLAALTVSGNGRQISTLDQWVTRLIDGVIAVHSVNQALHRILLEEVPFAGQWNYEEFKSEYQGRYRDLITASSGKHSSARDDVAGRVLAAAVEGVVHAAARHGELDSPALKAELGQMVRAYLRDRSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H316</accession>
    <name>A0A2S9H316_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7">Acyl-homoserine-lactone synthase</fullName>
            <ecNumber evidence="2 7">2.3.1.184</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Autoinducer synthesis protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_0995</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>a fatty acyl-[ACP] + S-adenosyl-L-methionine = an N-acyl-L-homoserine lactone + H(+) + holo-[ACP] + S-methyl-5'-thioadenosine</text>
            <dbReference type="Rhea" id="RHEA:10096"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="Rhea" id="RHEA-COMP:14125"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17509"/>
            <dbReference type="ChEBI" id="CHEBI:55474"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:138651"/>
            <dbReference type="EC" id="2.3.1.184"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="6 7">Belongs to the autoinducer synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.184" evidence="2 7"/>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94374">
        <property type="protein sequence ID" value="PRC94374"/>
        <property type="gene ID" value="S2091_0995"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061579">
        <property type="term" value="F:N-acyl homoserine lactone synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009372">
        <property type="term" value="P:quorum sensing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018311">
        <property type="entry name" value="Autoind_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001690">
        <property type="entry name" value="Autoind_synthase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39322">
        <property type="entry name" value="PTHR39322"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00765">
        <property type="entry name" value="Autoind_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01549">
        <property type="entry name" value="AUTOINDCRSYN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00949">
        <property type="entry name" value="AUTOINDUCER_SYNTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51187">
        <property type="entry name" value="AUTOINDUCER_SYNTH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 7" id="KW-0071">Autoinducer synthesis</keyword>
    <keyword evidence="3 6 7" id="KW-0673">Quorum sensing</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 7" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022654"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC94374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="194" mass="21993" checksum="E0DDBFC8B77A7326" modified="2018-07-18" version="1">MGSTIQINQRNEFNRNDLRDMHVLRAKVFKDRMGWEVPVLAGMEIDGYDALEPHYMVIRDDDNKVCGTWRMMPTEGPYMLKDTFPELLHGATAPEQERIWELSRFAIETDGDSKFGFAERAIAAMRGIVEFADKQGIDKYVTVTTTAIERLLRHTGVETSRMGPPLQVGVERAVALEIHLGEKTRTALFGNAVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H324</accession>
    <name>A0A2S9H324_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1005</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94384">
        <property type="protein sequence ID" value="PRC94384"/>
        <property type="gene ID" value="S2091_1005"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="30"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="80"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="129"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="152"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="198" mass="21949" checksum="E67256F2689C8E99" modified="2018-07-18" version="1">MELTRKIAIGILPWAAFNLLLHFTPPRYLVLVWLLLIASQLILGWRALREGNPVAIVALALFLGLFANGYTGILPWANDYASTLCYAALAVTALATVLLRAPFTASQGRRYVPQEFWQHPNFIRINQHLSLAWAVTFALNGVLMTLSHSWPLSSQLACYVSLAAAIVFSDRYPASARQRAAQLAEQAMRNRVQFPVAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3C7</accession>
    <name>A0A2S9H3C7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0987</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94366">
        <property type="protein sequence ID" value="PRC94366"/>
        <property type="gene ID" value="S2091_0987"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="95" mass="10774" checksum="D74E5851E52C5E74" modified="2018-07-18" version="1">MHTQQRPPRNTHLAIDTIDAYTQARDIVSDLSAIFEVLDHLALTDFSNKRITPILFRAGFGHATEQLKFIEEKISDSYKTLDELKTDSSHTSATK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3J1</accession>
    <name>A0A2S9H3J1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Addiction module antitoxin, RelB/DinJ family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0534</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RelB/DinJ antitoxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94531">
        <property type="protein sequence ID" value="PRC94531"/>
        <property type="gene ID" value="S2091_0534"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000987">
        <property type="term" value="F:cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015643">
        <property type="term" value="F:toxic substance binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044010">
        <property type="term" value="P:single-species biofilm formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1220.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013321">
        <property type="entry name" value="Arc_rbn_hlx_hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026262">
        <property type="entry name" value="DinJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007337">
        <property type="entry name" value="RelB/DinJ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38781">
        <property type="entry name" value="PTHR38781"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04221">
        <property type="entry name" value="RelB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003108">
        <property type="entry name" value="DinJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02384">
        <property type="entry name" value="RelB_DinJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="88" mass="9533" checksum="DA55AF4775CD8DC1" modified="2018-07-18" version="1">MPTTAGASVVRARIDTATKERAADALEAMGLTISDAIRMLMLRIADEQKLPFDVKVPSAALRQAITEPDSGQSFETVDSFMNYLNADD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3P9</accession>
    <name>A0A2S9H3P9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative signal transduction protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0617</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94614">
        <property type="protein sequence ID" value="PRC94614"/>
        <property type="gene ID" value="S2091_0617"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013976">
        <property type="entry name" value="HDOD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08668">
        <property type="entry name" value="HDOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51833">
        <property type="entry name" value="HDOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HDOD" evidence="1">
        <location>
            <begin position="24"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="288" mass="31815" checksum="94DFAE2BFE1DE334" modified="2018-07-18" version="1">MKTPPASAAPTEQSIEKMLNTIRIPPRPSLLSEVQQELACADPSPQKLAHIIAQDVAMAGALLKLANSAYIGLKLKAKSVEQAVNRLGIEQCSLLLTGIVMRETFHIEGVSLTEFWDNSTRRAQAMSYLAKKMTLCRSDIAHTFGLFCNIGVPLLLAKYPNYYAVLETADPDQHQQLAVFEEQHFNTSHAALGALMARTWGLPDEVVEAILLHHHYAVLHDHSSDSTVRNLIALALLVDYGIHRYYSQQQFPEWEAGGAEVCAYLGMSQSEADDISDEVNALFDVDLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H457</accession>
    <name>A0A2S9H457_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fatty acid hydroxylase superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0767</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94764">
        <property type="protein sequence ID" value="PRC94764"/>
        <property type="gene ID" value="S2091_0767"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008610">
        <property type="term" value="P:lipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006694">
        <property type="entry name" value="Fatty_acid_hydroxylase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04116">
        <property type="entry name" value="FA_hydroxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="5"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="77"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="135"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="302"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="326"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="359"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="383"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="domain" description="Fatty acid hydroxylase" evidence="2">
        <location>
            <begin position="81"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="417" mass="47840" checksum="94DC783EB303E9C0" modified="2018-07-18" version="1">MQEQVITIASPIFILLIIIEMFIAFRRGKSNFHFSDTINSMSLGMLSQITSAFLKLFLIGIYAWVAHNFALFKLPNAWWVWVAGLLVYDFLYYWLHRSGHEIAVLWAAHVVHHQSERYNLTTALRQTSSGPLLAWIFYLPLAILGVPIEMFIAISLIDLLYQFWVHTELIGKLGWFDRVFVSPSNHRVHHATNDIYLDKNYGGILILWDRLFGTFIEEMDEHKVVYGTRSPLRSWNPVKANIEVYQAIIRDAKRASNWTDKIRIWFKHPGWQPTDVAQQFPHAPFILHRPNFEPVLPTSWKCYCGAQFLLILSITTHFLAVDRTISFANCALYGFWLGAGLLILGGLTERRSNYLWLESIRLILTAGFVLFTGNWFGEFALPALGQGAVLFVTMSSLLSLVVLFKGANLNSNLQQKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4E6</accession>
    <name>A0A2S9H4E6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_0050</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94855">
        <property type="protein sequence ID" value="PRC94855"/>
        <property type="gene ID" value="S2091_0050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007844">
        <property type="entry name" value="AsmA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032712">
        <property type="entry name" value="AsmA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011836">
        <property type="entry name" value="CHP02099"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025263">
        <property type="entry name" value="DUF3971"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38690">
        <property type="entry name" value="PTHR38690"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05170">
        <property type="entry name" value="AsmA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13502">
        <property type="entry name" value="AsmA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13116">
        <property type="entry name" value="DUF3971"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02099">
        <property type="entry name" value="TIGR02099"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="36"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="domain" description="AsmA" evidence="2">
        <location>
            <begin position="43"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="domain" description="DUF3971" evidence="3">
        <location>
            <begin position="594"/>
            <end position="888"/>
        </location>
    </feature>
    <feature type="domain" description="AsmA_2" evidence="4">
        <location>
            <begin position="1130"/>
            <end position="1383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC94855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="1389" mass="152479" checksum="50EAB12D6490286C" modified="2018-07-18" version="1">MTSDQRITEITPHPYADRWHLFQRAYTRLNLISHHILGACVKLLVLLYLLFCVVFLVLRYALLPNIGNYKTEIEHLLGSSLGRTVSIAQISASWQGLHPHLQLQQVAIHDEQGQNALMLPSVNATISWMSVFVADVRLYNLEINQPELELKRSADGKIYIAGWWLDPAKKSDARGLNWLLSQREIVINNGILHWTDEQRGAPVLALSNVNLVMKNHWQHHQFSFTANPPANLSGPLDIRADFTHHAFSENISDYLQWKGQVYADFSKTDLAAWKSYFDYPFDLQQGVGAVRAWFTFDRAKIVDFTADLKLTDVKTWLRKDLQTLDLLSVSGRISVQELSAPKSLSSVGTSLMSPFAASVSEYIRDNGHQIALTNFSFETRSGFRLPPTTFIEKYIPANKSSAEQLQFSAKFLDLKVLANLIEHFPMPKEYAAMLQNFEPAGQLSNFSVKLQGKFPALEHYQISGEFANLAMKPQAARQALNDSLAFPAIPGFTNLTGQIDADEKKGSIQLVSTNLQLQLPDYFSEPEMLFDRFDMQANWLFQKDNQLQLSLAKLDFTQQAMQAHFSGTHIIPINPNKTKPLGVLDLTGSISHFDVQKINNYLPLATQPDLHKWLTTGLLQGTVDDVSVRIRGDLSEFPFVKKGLLDQNIFNVSGKIVDGKINYLPGVLGKDGTHPFWPILSKIQGKIVFDRESMEINAESGETDEIPVSKVKARIANLIGSNPVLEIDGNAVGPVQNMLHYLSVSPVLEWIGNFTQDTKATGNAKLKLRLDLPLMHIMDAKVAGDVQLMANDIGLLRDMPLLSQVTGRIDFNERGLSLNSLKGGFLGGAVTVVGGTQKDGVIRVKAEGVVAADGVRKAYPQPQLKHLLTRIDGNAPYTAIIQVKNKQTEIWVDSTLQGMALHLPVPVNKTAADNLPLHFELIATPLGANSGAVLQDEIKLSLGGMVNAHYVRQQASETSPWKVISGGVGVNVPAPTPDTGLSAHLELASLNVDELQALMPDKATGSTANKSADSALPEFDLSPYLEPNVLAAQAVELTLLGKKLDHVILGASRVNGIWQANIDSKQISGYVTWDNADHGLGHVTARLGSLIIPEAAANDVVDLLQNKNVHTDIPGLDVIAENVELFGKKLGRLELQAKNVSNPNDVNANEWQIDKLSLISPDAELSAQGKWTNSDHNHQIKSQTDLNYELTLTNAGKLLDRLGYAHVISGGKGKLTGEVSWSGSPYSMDIPSLSGKIKLDLQAGQFLKVEPGAAKLLAVLNLQALPRRLLLDFRDVFSDGFAFDGITGDADIEKGVAKTDNFKMRSVSATVLLSGTANIAGETQDLHVVVVPEVNAGAASVVYGLAVNPVIGLGTFLAQLFLREPLMKAFTFEYQITGPWKEPSVVKLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4G0</accession>
    <name>A0A2S9H4G0_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Antitoxin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0070</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Antitoxin component of a type II toxin-antitoxin (TA) system.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the phD/YefM antitoxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94875">
        <property type="protein sequence ID" value="PRC94875"/>
        <property type="gene ID" value="S2091_0070"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006442">
        <property type="entry name" value="Antitoxin_Phd/YefM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036165">
        <property type="entry name" value="YefM-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02604">
        <property type="entry name" value="PhdYeFM_antitox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143120">
        <property type="entry name" value="SSF143120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009981"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU362080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="90" mass="10412" checksum="B72FBED53F183A22" modified="2018-07-18" version="1">MKFSEQIKPISYLKSHAAEIIRDFDNNKNPLIITQNGEAKMVVMDIRSYEQQQETMALLKILALGNQQIEQGKFQDSASFFAEMEQEDQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4N3</accession>
    <name>A0A2S9H4N3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Branched-chain amino acid transport system / permease component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">S2091_0134</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94939">
        <property type="protein sequence ID" value="PRC94939"/>
        <property type="gene ID" value="S2091_0134"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015658">
        <property type="term" value="F:branched-chain amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06581">
        <property type="entry name" value="TM_PBP1_LivM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001851">
        <property type="entry name" value="ABC_transp_permease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032823">
        <property type="entry name" value="BCA_ABC_TP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043428">
        <property type="entry name" value="LivM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12399">
        <property type="entry name" value="BCA_ABC_TP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02653">
        <property type="entry name" value="BPD_transp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-1278">Translocase</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="23"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="52"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="77"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="104"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="152"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="201"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="227"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="252"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="276"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="302"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="325"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="385"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="417"/>
            <end position="424"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PRC94939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="643" mass="68523" checksum="EC79BD6DB79CB5AC" modified="2018-07-18" version="1">MLALSVLGVAALALFPTLIPNPYYIHLAETILIYAILLFGLDIVVGYTGQVSLGHAGLFGIGSYATGVLVFKLAAPFWIGIPASIAAAALFGAILALPALRVTGPYLAMVTLAFGTIIEILINEMDFLTNGPMGIKIAKPVIFGVKLGEVGYYYLVAALMLLSLVVVHRILKSNLGRAFEALRDSPIASDCMGVSVYRYKVYAFVISAGFAGLAGSLYAYSEEYISPNTYNFELTILFLLAVIMGGRKTRSGALLGALIVVMLPSLLADIDLFRQIAVTAAVLGVAGGAYMLIKKRSTVRGVIVPLVATIGMAGFSYHLENIIDWRLTIFGLMTLFVVYYLQDGIVGFLHGLIGKRATQEPLATASATAASFARAQGGTNGDTLLRVDQVLMAFGGLKALNQVSLNVLQGSVHGLIGPNGSGKSTMMNILTGIYRPTSGKVEFAGAMISGRTTSEIALGGVARTFQNVELFGEMTATENVLVGLHHTFKSNILDIMLQTPRYRREERAARARAASILEFVGLADLASEEARNLPYGKQRLLEIGRALGLSPRLLLLDEPAAGLTAPDIRDLIAIIRKIREYGITIILIEHHMDVVMTLSDVVTVLDFGQKIAEGAPAVVQGDPKVIEAYLGGLSDAVTPSTAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4S2</accession>
    <name>A0A2S9H4S2_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_0162</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94967">
        <property type="protein sequence ID" value="PRC94967"/>
        <property type="gene ID" value="S2091_0162"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="27"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="223"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="8">
        <location>
            <begin position="242"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="7">
        <location>
            <begin position="304"/>
            <end position="502"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC94967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="502" mass="55836" checksum="ECE3DAF5481127EA" modified="2018-07-18" version="1">MPKNAIVTKPEMKLPRRWLLRLLPTSLLGRLTIVLMMGVLLTQFVGNAFWAAQVRKESEIEVAASSQHLAQSAASSIRYFLSLPTNYRPLIIQQFREMGGTRFFVNINSAPIDIHDIGQYALAELAKKKIKAELLEKIPQLAGANNLKLGFSWPAELVVSEDGAGINDLPDNWIQHILITKPNPAPILVIQAELEPGNWLYLATLMPNPYFLNSNNPFSTDRVVLLGLSLAAVFLLSMLVVRWITRPLEALSVAATAFGNGNGEAMPHLPETGSREFVNTARAFSVMRERIQRYIEDRERLFVSISHDLRTPIMRLKLRAELLDDDLLRSEFNEDLDELDMMVKGALQCVKDNDIYENPTEVKLDALLNRMVRGAQLAGHKVEFSESGICVVAKPLALKRAIGNLLDNALHYGNHVEISVLQNDVQVEITLRDHGPGVPEEALIYLFDPYVRLEHGQLKNNSGMGLGLGIAQAIVLAHNGTLILRNHPEGGLCATIVLPVQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H538</accession>
    <name>A0A2S9H538_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Gamma-glutamyl phosphate reductase</fullName>
            <shortName evidence="7">GPR</shortName>
            <ecNumber evidence="7">1.2.1.41</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Glutamate-5-semialdehyde dehydrogenase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Glutamyl-gamma-semialdehyde dehydrogenase</fullName>
            <shortName evidence="7">GSA dehydrogenase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">proA</name>
        <name evidence="9" type="ORF">S2091_0294</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>L-glutamate 5-semialdehyde + NADP(+) + phosphate = H(+) + L-glutamyl 5-phosphate + NADPH</text>
            <dbReference type="Rhea" id="RHEA:19541"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58066"/>
            <dbReference type="ChEBI" id="CHEBI:58274"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.2.1.41"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Amino-acid biosynthesis; L-proline biosynthesis; L-glutamate 5-semialdehyde from L-glutamate: step 2/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the gamma-glutamyl phosphate reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.41" evidence="7"/>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95099">
        <property type="protein sequence ID" value="PRC95099"/>
        <property type="gene ID" value="S2091_0294"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00098">
        <property type="reaction ID" value="UER00360"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004350">
        <property type="term" value="F:glutamate-5-semialdehyde dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055129">
        <property type="term" value="P:L-proline biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd07079">
        <property type="entry name" value="ALDH_F18-19_ProA-GPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00412">
        <property type="entry name" value="ProA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012134">
        <property type="entry name" value="Glu-5-SA_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000965">
        <property type="entry name" value="GPR_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000151">
        <property type="entry name" value="GPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00407">
        <property type="entry name" value="proA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 7" id="KW-0521">NADP</keyword>
    <keyword evidence="6 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4 7" id="KW-0641">Proline biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldedh" evidence="8">
        <location>
            <begin position="9"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="domain" description="Aldedh" evidence="8">
        <location>
            <begin position="312"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00412"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC95099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="421" mass="45344" checksum="E4723160FC96C5ED" modified="2018-07-18" version="1">MDIANYMQQIGQQAKSASRLMARASSAQKNQALRLIAAAILREAVAIRAANHIDMEAARATGLAPAMLDRLSLSEQAINNMAEGLLQIAALPDPIGEITDLKFRPSGIQVGQMRVSLGVIGIIYEARPNVTVDAAGLCIKSGNATILRGGSEAIHCNQALAKLVQEGLLGAGLPVQAVQVIETTDRAAVGQLITMPEFVDVIVPRGGKGLIERLIKESTVPMIKHLDGICHVYIDDKADLVKAANIAFNAKCHRYGTCNTMETLLVARPIAAQILPKLATLYARKQVELRCDAEAFALLADYPYLVAAQEADWSTEYLAPILSIKIVSDLDEAITHINHYSSQHTDTLVSEDYSRALRFMREVDSASVIVNASTRFADGFEFGLGAEIGISTDKLHARGPVGLHGLTSVKYVVFGHGEVRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H571</accession>
    <name>A0A2S9H571_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Winged helix DNA-binding domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0211</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95016">
        <property type="protein sequence ID" value="PRC95016"/>
        <property type="gene ID" value="S2091_0211"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027395">
        <property type="entry name" value="WH_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13601">
        <property type="entry name" value="HTH_34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH_34" evidence="1">
        <location>
            <begin position="13"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC95016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="96" mass="11026" checksum="BBB9C9B71CE0B13E" modified="2018-07-18" version="1">MPGLDEIIHQSMRLRIMTSLNVLKKEEWIEFVRLKSLVEASDGNLGAHLDTLARANYVEIDKQFVGKKPQTRIRATTQGRNAFKHHVTALRNLLDM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5A6</accession>
    <name>A0A2S9H5A6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0365</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95170">
        <property type="protein sequence ID" value="PRC95170"/>
        <property type="gene ID" value="S2091_0365"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC95170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="33" mass="3706" checksum="D4A04121098E4000" modified="2018-07-18" version="1">MQITLLAIAKDANVRGSQILALFYQMRLNQLGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5F0</accession>
    <name>A0A2S9H5F0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alpha amylase, catalytic domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0383</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95188">
        <property type="protein sequence ID" value="PRC95188"/>
        <property type="gene ID" value="S2091_0383"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015171">
        <property type="entry name" value="Cyc-maltodext_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019492">
        <property type="entry name" value="Cyclo-malto-dextrinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="Glyco_hydro_13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10438">
        <property type="entry name" value="Cyc-maltodext_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09087">
        <property type="entry name" value="Cyc-maltodext_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00642">
        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="SSF81296"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015597747" evidence="1">
        <location>
            <begin position="24"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="domain" description="Aamy" evidence="2">
        <location>
            <begin position="133"/>
            <end position="531"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC95188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="619" mass="69809" checksum="43087AEF30D0F2E4" modified="2018-07-18" version="1">MMKKIVFNFTMLITLVMSAGAFASTNNIERIEPGSWWVGMKSDRLQLMVHGDNIAAYTVDVTYPGVRIDSVATVKNRNYVFINLIIQPDAVAGSVDLLFKNGGKLITYPYPLLARVKNSANRKGFSNSDVILNLVPDRFANGDPRNDNVVGFTDRLNRSSNEAGRHGGDIQGIIDHLDYIAAMGYTAIWPTPLIENNQKNYSYHGYAATDTYKIDARFGTNEDFKRMVALAKQKGIGVIQDIVLNHIGSEHWWMKDMPMQDWLSFDGKFVATKHAHSTVSDPYASKEDQKNFTAGWFTENMPDMNQQNPFVATYQIQNSIWWVEYAGLSGIRVDTYGYSDTAFLSEWSHRLTDEYPNLNIVGEEWSLNPAIVSYWQKGKIHANGYVSYLPSLMDFPLNNALRNALVEDESMESGLSNLYKELANDSQYPNPSNLVLFEGNHDVSRLYSVLNDDVDLVKMALAYVLTAPRIPQLYYGTEILMKSKKERDDGAARQDFPGGWAGDKVNAFNGVGLTDEQKNLQNYLKKLLNWRKTQSAIHSGKLLHYTPDQGTYTYFRFDQHKIIMVVLNKNKISTELATKRFSEILGTHTNAVDVLSGKNITIEKSVTVPARSALILEVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5H0</accession>
    <name>A0A2S9H5H0_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase</fullName>
            <ecNumber evidence="6 7">6.3.2.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">D-alanyl-D-alanine-adding enzyme</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">murF</name>
        <name evidence="11" type="ORF">S2091_0403</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 7">Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>ATP + D-alanyl-D-alanine + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptanedioate = ADP + H(+) + phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine</text>
            <dbReference type="Rhea" id="RHEA:28374"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57822"/>
            <dbReference type="ChEBI" id="CHEBI:61386"/>
            <dbReference type="ChEBI" id="CHEBI:83905"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.10"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="6 7">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6 7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the MurCDEF family. MurF subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.10" evidence="6 7"/>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95208">
        <property type="protein sequence ID" value="PRC95208"/>
        <property type="gene ID" value="S2091_0403"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047480">
        <property type="term" value="F:UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008766">
        <property type="term" value="F:UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02019">
        <property type="entry name" value="MurF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036565">
        <property type="entry name" value="Mur-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004101">
        <property type="entry name" value="Mur_ligase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036615">
        <property type="entry name" value="Mur_ligase_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013221">
        <property type="entry name" value="Mur_ligase_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000713">
        <property type="entry name" value="Mur_ligase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035911">
        <property type="entry name" value="MurE/MurF_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005863">
        <property type="entry name" value="UDP-N-AcMur_synth"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01225">
        <property type="entry name" value="Mur_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02875">
        <property type="entry name" value="Mur_ligase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08245">
        <property type="entry name" value="Mur_ligase_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53244">
        <property type="entry name" value="SSF53244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53623">
        <property type="entry name" value="SSF53623"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63418">
        <property type="entry name" value="SSF63418"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01143">
        <property type="entry name" value="murF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 6 7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1 6 7" id="KW-0132">Cell division</keyword>
    <keyword evidence="2 6 7" id="KW-0133">Cell shape</keyword>
    <keyword evidence="5 6 7" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 11" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3 6 7" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mur_ligase" evidence="8">
        <location>
            <begin position="27"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="domain" description="Mur_ligase_M" evidence="10">
        <location>
            <begin position="108"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="domain" description="Mur_ligase_C" evidence="9">
        <location>
            <begin position="322"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="110"/>
            <end position="116"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF08245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC95208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="459" mass="48613" checksum="4D1B21B002502DA7" modified="2018-07-18" version="1">MRANLAQLKNSVTCLSQLIESLDVSFDGVVTDSRKITPGCLFVALRGEHFDAHDFLNDVIKLGAAAVVAERLPANFSLPALVVPDTRLALGEIAHYWRSQFALPVIAVTGSNGKTTVKEMISAILTAAFGGQFALATQGNLNNDIGVPQTIFRINDQHRAAVIELGMNHPGEIAQLAAIAQPTVGLVNNAQREHQEFMQSVEAVAQENGAVILSLPVDGVAVFPANDEYSDLWRSYAGSRKVISFGLAGQHGTSSPEISATHQATDFGSTLQVQIGSAPVEIELAAAGLHSVHNALAAIASCHAIGCSNDAIVAGLQSFKPVSGRLQKKQAHNSAVVIDDTYNANPDSVRAAIDVLAQATGQKILVLGDMGEVGVDGPAYHDEIGMYAKQQGIDVLYTLGTLACHSSATFGNAAQHFEKIEALLENLDTSLTSSSTVLIKGSRFMKMERVVVHLLNAQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GS81</accession>
    <name>A0A2S9GS81_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4737</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000059">
        <property type="protein sequence ID" value="PRC90555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90555">
        <property type="protein sequence ID" value="PRC90555"/>
        <property type="gene ID" value="S2091_4737"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003346">
        <property type="entry name" value="Transposase_20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002525">
        <property type="entry name" value="Transposase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01548">
        <property type="entry name" value="DEDD_Tnp_IS110"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02371">
        <property type="entry name" value="Transposase_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DEDD_Tnp_IS110" evidence="1">
        <location>
            <begin position="8"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="348" mass="38340" checksum="031F240672558B0B" modified="2018-07-18" version="1">MDTTVKMIGLDIAKNVFVAVGQNDHGKVVMKYKLAREAVLPTFANIPATTIGIEACAGSHYWARKLISLGHKVKLIAAQHTRAYVTGNKNDTNDAAAIAEACSRAATKTVPINTEAQQDLQMLHRTRQALMQERTATICRMRAFANEYGQVFPLGVAKFLSGFTKWLNDDKNGLSGSAMSTFRELKTQLDDKDTRIEVYDARLNQAAKEDARAAKIMEIPGVGKVVATAVLAAVADAHHFGNGRDFSANLGLVPREHSSGGKQRLYGITKRGDAYLRALLIHGARSALRWAGEKPDKMLRWATKLKERRGHNVAVTALANKMARIIWALLAYDREYVPVWSKSMIRPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSD0</accession>
    <name>A0A2S9GSD0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4694</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000045">
        <property type="protein sequence ID" value="PRC90605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90605">
        <property type="protein sequence ID" value="PRC90605"/>
        <property type="gene ID" value="S2091_4694"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC90605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="277" mass="31227" checksum="ED21ED294BBD4DC0" modified="2018-07-18" version="1">MRYMTTNKQLHPLLLILITLTCFLSSDVFGQTVNNPDLHKLPQVGFDWAVHPEIKPIAKVREYEEDPIVFDSPIAERLWKEIIQHTIVDVSSDFAKELMTGGSFISLKDNCYLVTYDAVYHICPNKKVFEQFSPSNPPGNTLTSDFFDLPNGNKWALISTNKLSRGIISFSFFAVVITKNKNEEENVKATLLAHGVENSDDPQSDAPCGTVEDRKGHSEFNNSATSYISHSITKDVAGYASQISFTVFQQNCKTLKSTKLRENYIFSGSDFIKIRKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSK1</accession>
    <name>A0A2S9GSK1_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Transport permease protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_4595</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell inner membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the ABC-2 integral membrane protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000038">
        <property type="protein sequence ID" value="PRC90702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90702">
        <property type="protein sequence ID" value="PRC90702"/>
        <property type="gene ID" value="S2091_4595"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000412">
        <property type="entry name" value="ABC_2_transport"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00164">
        <property type="entry name" value="ABC2TRNSPORT"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51012">
        <property type="entry name" value="ABC_TM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="170"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="224"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="251"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="281"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="342"/>
            <end position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC90702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="366" mass="40391" checksum="94BFB334B206BB1E" modified="2018-07-18" version="1">MWYAIITLIKKELQALFSSPQSRRMLIMPVLLQLLVFPFAATLEVKNSTLAIYNQDGGAASIELIQRLSAAEAFPKLIMINSETQLQQVIDRQQALLAIRLPQDFSRQIATGQAAKIQAIIDGRRSNSAQIAFSYAQLILQQFVLEQQPQAVPVQLTVQNLYNPNLEYRWFVLPSLVAIITTIGCLMVTALSLAREREEGTFDQLLVSPLTPAYIMVGKAVPGVLVALLQGSIIALAAVFVYRIPFTGSVWLLYLTMLCYGLSLAGFGLLISAMCANQQQAFLGTFGFMSPAVILSGYMAPVENMPPFLQVVSAMNPLSHAIIAIKGIFLKGYTFSQTWPQLWPLLLIASITLTLAYLIFIRRSGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSM5</accession>
    <name>A0A2S9GSM5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">SnoaL-like domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_4604</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000038">
        <property type="protein sequence ID" value="PRC90711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90711">
        <property type="protein sequence ID" value="PRC90711"/>
        <property type="gene ID" value="S2091_4604"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037401">
        <property type="entry name" value="SnoaL-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13474">
        <property type="entry name" value="SnoaL_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015504697" evidence="1">
        <location>
            <begin position="24"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="domain" description="SnoaL-like" evidence="2">
        <location>
            <begin position="36"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC90711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="169" mass="19666" checksum="8EE6D435AC781264" modified="2018-07-18" version="1">MNNLIFKFFLVLSIMLVAYSANAQTPDADAAFRQQVNAFLDEWHDDAAHANYRYFDKIAKEGVYIGTDKSERWVRDDFKAWAKPYFDKHKAWTFHAIKRNVAFSDDKSFIWFDEQLNTQMGICQASGVIRNTKDGLKIEHYQLSLTVPNPLVPQIQKEISDFDARQAHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GT09</accession>
    <name>A0A2S9GT09_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Serine/threonine protein phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4491</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000035">
        <property type="protein sequence ID" value="PRC90828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90828">
        <property type="protein sequence ID" value="PRC90828"/>
        <property type="gene ID" value="S2091_4491"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006470">
        <property type="term" value="P:protein dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00143">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015655">
        <property type="entry name" value="PP2C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832">
        <property type="entry name" value="PTHR13832"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00331">
        <property type="entry name" value="PP2C_SIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="SSF81606"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="1">
        <location>
            <begin position="81"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="326" mass="35120" checksum="743CD9800C17C1A5" modified="2018-07-18" version="1">MNCSFCNELAEPQFLFCEACGKPLVADVVVGDDLPAVENDNAAVGCIRCGCGSSRFDSDGYCEACGHRSSPLDAIDVLESGVQAASASHRGRHHSDNQDSVLMQELPNGFAIALADGVSTSCHARAAADIAVQTALKTLQDCGSLPTAERMRLATQRAHEAVCTLPHDNLQLAEPQATLVLALVEGMQVWYSWVGDSRLYMIDQAEVIQLTMDDSWLNAQVNTGVPIAAALKDINAHCITQCLGMRDDEVDIHIATQRLSPDAILLLCSDGLWNYCDEPKALRKLLNEGNVTDSLARRCVKLIDYANAAGGQDNITVAMYRHRCAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GT76</accession>
    <name>A0A2S9GT76_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4413</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000033">
        <property type="protein sequence ID" value="PRC90920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90920">
        <property type="protein sequence ID" value="PRC90920"/>
        <property type="gene ID" value="S2091_4413"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="413"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="417"/>
            <end position="454"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="460" mass="46949" checksum="8471E9E016D1129C" modified="2018-07-18" version="1">MDISPIDSTVIPTIKLDALADLDANAAPVAPLIASPQPDNVASIVIFSPLSQLLAATVKFQTQQANQTQQVSAGATTSTGTSLDFKQLSEITTLFVDAFNNFQTSIASSVANPFDSVFNNALLTGIQTENTQSGSSSIQSFIDSLAEVGINFQAGTDFMSPSQFQIDWTTLASAYNANPAQTSALLSNAFQALGAIEENLLLSQQGLNLPGNEINPVLYDGVSASQIDTSAVAAELNSLINAEGPNVYDSAQLLLASEQLIEALDANLIASQTAAAKTSAAVTAATVATNTVEDNLNIATTASNAELASIEVTPPLVVVTNPANSPAANALVSNSDVSVANANSAVINSVNANASTSVSNTQATLEAVVIDPLIAVAVAAYRVGEAISAIPSDKPLNPAPESIQDIDQIPKVAPVTSNLHGGSNEGGHNQAAHNAAPDQSAGISSESASVPVKTKVDVSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTB4</accession>
    <name>A0A2S9GTB4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4342</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000032">
        <property type="protein sequence ID" value="PRC90941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90941">
        <property type="protein sequence ID" value="PRC90941"/>
        <property type="gene ID" value="S2091_4342"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC90941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="70" mass="8291" checksum="10A74359E53ECA80" modified="2018-07-18" version="1">MSADHKLNNFTKKRKKYRQSLTDKKYGKYIQPNTSAHYIYSAFSVKQIFPRFTISGKYLHHNQQILPLGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTG0</accession>
    <name>A0A2S9GTG0_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 12">Phosphoribosylformylglycinamidine cyclo-ligase</fullName>
            <ecNumber evidence="3 12">6.3.3.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10 12">AIR synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11 12">AIRS</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9 12">Phosphoribosyl-aminoimidazole synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">purM</name>
        <name evidence="15" type="ORF">S2091_4308</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8 12">
            <text>2-formamido-N(1)-(5-O-phospho-beta-D-ribosyl)acetamidine + ATP = 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole + ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:23032"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:137981"/>
            <dbReference type="ChEBI" id="CHEBI:147287"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.3.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 12">Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole from N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide: step 2/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the AIR synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.3.1" evidence="3 12"/>
    <dbReference type="EMBL" id="PUGF01000031">
        <property type="protein sequence ID" value="PRC91012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91012">
        <property type="protein sequence ID" value="PRC91012"/>
        <property type="gene ID" value="S2091_4308"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00129"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004641">
        <property type="term" value="F:phosphoribosylformylglycinamidine cyclo-ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02196">
        <property type="entry name" value="PurM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.650.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00741">
        <property type="entry name" value="AIRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010918">
        <property type="entry name" value="PurM-like_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036676">
        <property type="entry name" value="PurM-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016188">
        <property type="entry name" value="PurM-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036921">
        <property type="entry name" value="PurM-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004733">
        <property type="entry name" value="PurM_cligase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10520">
        <property type="entry name" value="PTHR10520"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00586">
        <property type="entry name" value="AIRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02769">
        <property type="entry name" value="AIRS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55326">
        <property type="entry name" value="SSF55326"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56042">
        <property type="entry name" value="SSF56042"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00878">
        <property type="entry name" value="purM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 12 15" id="KW-0436">Ligase</keyword>
    <keyword evidence="6 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AIRS" evidence="13">
        <location>
            <begin position="62"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="domain" description="AIRS_C" evidence="14">
        <location>
            <begin position="179"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00031908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00032931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00033093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="PRC91012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="347" mass="36624" checksum="0136007CC4163333" modified="2018-07-18" version="1">MTSSSKVSLSYRDAGVDIDAGDALIDVIKPYAKRTMREGVLAGIGGFGALFEVSKKYKEPVLVAGTDGVGTKLKLAFHLNRHDTVGIDLVAMSVNDILVQGAEPLFFLDYFACGKLNVAAAADVIKGVALGCEQAGCALIGGETAEMPSMYPDGEYDLAGFAVGAVEKSKIIDGSKITPSDVVLGLASSGAHSNGYSLVRKIIEVAQPDLDGDFHGKKLADVLMAPTRIYVKPLLALIESLEVKGMAHITGGGLVENVPRVLGKHLTAILDHSKWVMPPLFTWLQEHGNVADAEMHRVFNCGIGMVVIVSKENAAAALAQLTAAGEQVWQIGEIRARAGDEAQTQVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTP8</accession>
    <name>A0A2S9GTP8_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 8">Ferrochelatase</fullName>
            <ecNumber evidence="7 8">4.99.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Heme synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Protoheme ferro-lyase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">hemH</name>
        <name evidence="9" type="ORF">S2091_4190</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7 8">Catalyzes the ferrous insertion into protoporphyrin IX.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7 8">
            <text>2 H(+) + heme b = Fe(2+) + protoporphyrin IX</text>
            <dbReference type="Rhea" id="RHEA:22584"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:57306"/>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
            <dbReference type="EC" id="4.99.1.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>Fe-coproporphyrin III + 2 H(+) = coproporphyrin III + Fe(2+)</text>
            <dbReference type="Rhea" id="RHEA:49572"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:68438"/>
            <dbReference type="ChEBI" id="CHEBI:131725"/>
            <dbReference type="EC" id="4.99.1.9"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="6">
            <dbReference type="Rhea" id="RHEA:49574"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="7 8">Porphyrin-containing compound metabolism; protoheme biosynthesis; protoheme from protoporphyrin-IX: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7 8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7 8">Belongs to the ferrochelatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.99.1.1" evidence="7 8"/>
    <dbReference type="EMBL" id="PUGF01000029">
        <property type="protein sequence ID" value="PRC91094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91094">
        <property type="protein sequence ID" value="PRC91094"/>
        <property type="gene ID" value="S2091_4190"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00252">
        <property type="reaction ID" value="UER00325"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004325">
        <property type="term" value="F:ferrochelatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006783">
        <property type="term" value="P:heme biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00419">
        <property type="entry name" value="Ferrochelatase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03411">
        <property type="entry name" value="Ferrochelatase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00323">
        <property type="entry name" value="Ferrochelatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001015">
        <property type="entry name" value="Ferrochelatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019772">
        <property type="entry name" value="Ferrochelatase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033644">
        <property type="entry name" value="Ferrochelatase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033659">
        <property type="entry name" value="Ferrochelatase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11108">
        <property type="entry name" value="PTHR11108"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00762">
        <property type="entry name" value="Ferrochelatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00109">
        <property type="entry name" value="hemH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00534">
        <property type="entry name" value="FERROCHELATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 7 8" id="KW-0350">Heme biosynthesis</keyword>
    <keyword evidence="2 7 8" id="KW-0408">Iron</keyword>
    <keyword evidence="4 7 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 7 8" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="7">
        <location>
            <position position="208"/>
        </location>
        <ligand>
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="289"/>
        </location>
        <ligand>
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC91094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="365" mass="41065" checksum="BED1132F3B21BE08" modified="2018-07-18" version="1">MSKNSSSFQHGKASKTAVVLVNLGTPEAPTAKALRPYLKEFLSDTRVVEIPRLIWWFILNCIILPFRSKQSAAKYAAIWTAEGSPLKVHTLKQATLLRGYLGERGHQVDVVAAMRYGQPAVSDVLNQLQKNGCERVLILPAYPQYSGTTTASIFDAVSTHYKKIRNIPELRFIKHYHDHDGYILALKNSIFKHWEQNKRAGHLVMSFHGVPKRTLLLGDPYHCECHKTARLLAQSLGLKEDEYSVTFQSRFGKAEWLQPYTLPSIEALAKSGTRRVDVICPGFTSDCLETLEEINIEVRAAFMLAGGKEFHYIPCLNEDALWLRALAEITEPHLHAWPTSFEALRDVQQQAAASVVWAKKIGATQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTW0</accession>
    <name>A0A2S9GTW0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transposase DDE domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_4163</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000028">
        <property type="protein sequence ID" value="PRC91162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91162">
        <property type="protein sequence ID" value="PRC91162"/>
        <property type="gene ID" value="S2091_4163"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025399">
        <property type="entry name" value="DUF4372"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002559">
        <property type="entry name" value="Transposase_11"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01609">
        <property type="entry name" value="DDE_Tnp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14294">
        <property type="entry name" value="DUF4372"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4372" evidence="2">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="domain" description="DDE_Tnp_1" evidence="1">
        <location>
            <begin position="101"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="377" mass="43891" checksum="C44DFFF87316580D" modified="2018-07-18" version="1">MPRGSFDAIVEKHKANKYTKQFGYWQHAVAMIYAQLSGASSLRELQAGFNGHAAHHYHLGACAIKKSTLADANSRRKDAVFIDVVQLLMQKASRSVRQQTKEWLCLLDSTPIMLKGREFDRWTDESKTHRTQGLKLHVLYDTQTEVPTWQSITAPNVNDVSKAWDVPLQKGVTYVFDKGYCDDGWWREIDLAGAQFVTRFKNNAGIGIEEELPIAEADKGIVISDQLVRFKHRRTRGQRKSYYERTLRRITIVREDKATPLVLATNDLTRSAKEIAQNYKERWGIELFFKWIKQHLKIKSFYGRTENAVRIQLLTALIGYLLVALHKQTHQIKATLWECLCLLRATLFQRKELDEHRERKRRQREQKMNQYQIGLFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GU01</accession>
    <name>A0A2S9GU01_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 7">6,7-dimethyl-8-ribityllumazine synthase</fullName>
            <shortName evidence="7">DMRL synthase</shortName>
            <shortName evidence="7">LS</shortName>
            <shortName evidence="7">Lumazine synthase</shortName>
            <ecNumber evidence="4 7">2.5.1.78</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ribH</name>
        <name evidence="9" type="ORF">S2091_4110</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>(2S)-2-hydroxy-3-oxobutyl phosphate + 5-amino-6-(D-ribitylamino)uracil = 6,7-dimethyl-8-(1-D-ribityl)lumazine + H(+) + 2 H2O + phosphate</text>
            <dbReference type="Rhea" id="RHEA:26152"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15934"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58201"/>
            <dbReference type="ChEBI" id="CHEBI:58830"/>
            <dbReference type="EC" id="2.5.1.78"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Cofactor biosynthesis; riboflavin biosynthesis; riboflavin from 2-hydroxy-3-oxobutyl phosphate and 5-amino-6-(D-ribitylamino)uracil: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the DMRL synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.78" evidence="4 7"/>
    <dbReference type="EMBL" id="PUGF01000027">
        <property type="protein sequence ID" value="PRC91215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91215">
        <property type="protein sequence ID" value="PRC91215"/>
        <property type="gene ID" value="S2091_4110"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00275">
        <property type="reaction ID" value="UER00404"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009349">
        <property type="term" value="C:riboflavin synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000906">
        <property type="term" value="F:6,7-dimethyl-8-ribityllumazine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd09209">
        <property type="entry name" value="Lumazine_synthase-I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.960">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00178">
        <property type="entry name" value="Lumazine_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034964">
        <property type="entry name" value="LS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002180">
        <property type="entry name" value="LS/RS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036467">
        <property type="entry name" value="LS/RS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21058">
        <property type="entry name" value="PTHR21058"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00885">
        <property type="entry name" value="DMRL_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52121">
        <property type="entry name" value="SSF52121"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00114">
        <property type="entry name" value="lumazine-synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0686">Riboflavin biosynthesis</keyword>
    <keyword evidence="6 7" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="5-amino-6-(D-ribitylamino)uracil binding" evidence="7">
        <location>
            <begin position="51"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="5-amino-6-(D-ribitylamino)uracil binding" evidence="7">
        <location>
            <begin position="75"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="1-deoxy-L-glycero-tetrulose 4-phosphate binding" evidence="7">
        <location>
            <begin position="80"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="130"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="7">
        <location>
            <position position="83"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="17"/>
        </location>
        <ligand>
            <name>5-amino-6-(D-ribitylamino)uracil</name>
            <dbReference type="ChEBI" id="CHEBI:15934"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="108"/>
        </location>
        <ligand>
            <name>5-amino-6-(D-ribitylamino)uracil</name>
            <dbReference type="ChEBI" id="CHEBI:15934"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="122"/>
        </location>
        <ligand>
            <name>(2S)-2-hydroxy-3-oxobutyl phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58830"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007424"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC91215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="158" mass="16635" checksum="ED02BEAC8034FB0A" modified="2018-07-18" version="1">MNLDGAGVRVGIVQARFNPEIGDALFTACVAELQALGVIGEDILHVTVPGALEIPLALQKLADTQQFDALIALGAIIRGETYHFELVSNESGAGITRIGLDFGLPIANAVLTTENDAQAVARMHEKGRDAARVAVEMANLTLALEELAENAKDANFDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GU55</accession>
    <name>A0A2S9GU55_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 5">Thymidylate synthase</fullName>
            <shortName evidence="5">TS</shortName>
            <shortName evidence="5">TSase</shortName>
            <ecNumber evidence="1 5">2.1.1.45</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">thyA</name>
        <name evidence="8" type="ORF">S2091_4016</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + dUMP = 7,8-dihydrofolate + dTMP</text>
            <dbReference type="Rhea" id="RHEA:12104"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:57451"/>
            <dbReference type="ChEBI" id="CHEBI:63528"/>
            <dbReference type="ChEBI" id="CHEBI:246422"/>
            <dbReference type="EC" id="2.1.1.45"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5">Pyrimidine metabolism; dTTP biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.45" evidence="1 5"/>
    <dbReference type="EMBL" id="PUGF01000026">
        <property type="protein sequence ID" value="PRC91231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91231">
        <property type="protein sequence ID" value="PRC91231"/>
        <property type="gene ID" value="S2091_4016"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00575"/>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004799">
        <property type="term" value="F:thymidylate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006231">
        <property type="term" value="P:dTMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006235">
        <property type="term" value="P:dTTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00351">
        <property type="entry name" value="TS_Pyrimidine_HMase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.572.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00008">
        <property type="entry name" value="Thymidy_synth_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045097">
        <property type="entry name" value="Thymidate_synth/dCMP_Mease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023451">
        <property type="entry name" value="Thymidate_synth/dCMP_Mease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036926">
        <property type="entry name" value="Thymidate_synth/dCMP_Mease_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000398">
        <property type="entry name" value="Thymidylate_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020940">
        <property type="entry name" value="Thymidylate_synthase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11548">
        <property type="entry name" value="PTHR11548"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00303">
        <property type="entry name" value="Thymidylat_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00108">
        <property type="entry name" value="THYMDSNTHASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55831">
        <property type="entry name" value="SSF55831"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03284">
        <property type="entry name" value="thym_sym"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00091">
        <property type="entry name" value="THYMIDYLATE_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4 5" id="KW-0545">Nucleotide biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thymidylat_synt" evidence="7">
        <location>
            <begin position="2"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="146"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="5">
        <location>
            <position position="146"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="21"/>
        </location>
        <ligand>
            <name>dUMP</name>
            <dbReference type="ChEBI" id="CHEBI:246422"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="51"/>
        </location>
        <ligand>
            <name>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate</name>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="126"/>
            <end position="127"/>
        </location>
        <ligand>
            <name>dUMP</name>
            <dbReference type="ChEBI" id="CHEBI:246422"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="166"/>
            <end position="169"/>
        </location>
        <ligand>
            <name>dUMP</name>
            <dbReference type="ChEBI" id="CHEBI:246422"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="169"/>
        </location>
        <ligand>
            <name>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate</name>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="177"/>
        </location>
        <ligand>
            <name>dUMP</name>
            <dbReference type="ChEBI" id="CHEBI:246422"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="207"/>
            <end position="209"/>
        </location>
        <ligand>
            <name>dUMP</name>
            <dbReference type="ChEBI" id="CHEBI:246422"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="263"/>
        </location>
        <ligand>
            <name>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate</name>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC91231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="264" mass="30229" checksum="E30A486ABA4FCDE5" modified="2018-07-18" version="1">MQQYLDLMRHVQQHGTEKTDRTGTGTRSVFGHQMRFDLAQGFPLVTTKKLHLKSIIHELIWFLNGSTNIAYLKENGVSIWDDWADEQGNLGPVYGYQWRSWPTPNGEHIDQISQVMEQIKHNPDSRRMIVSAWNVADIPNMKLPPCHAFFQFYVADGKLSCQLYQRSADIFLGVPFNIASYALLTHMMAQQAGLEVGDFIWSGGDCHLYSNHLEQVELQLSRTPLALPQLNIKRVPPSIFDYTFDDFEILNYQSHPHIKAAVAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUF6</accession>
    <name>A0A2S9GUF6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4009</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000025">
        <property type="protein sequence ID" value="PRC91338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91338">
        <property type="protein sequence ID" value="PRC91338"/>
        <property type="gene ID" value="S2091_4009"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1220.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013321">
        <property type="entry name" value="Arc_rbn_hlx_hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002145">
        <property type="entry name" value="CopG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010985">
        <property type="entry name" value="Ribbon_hlx_hlx"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01402">
        <property type="entry name" value="RHH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47598">
        <property type="entry name" value="SSF47598"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RHH_1" evidence="1">
        <location>
            <begin position="9"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01402"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="89" mass="10015" checksum="F10BC7114EDE631E" modified="2018-07-18" version="1">MAQAETKVLTAHVPLPLADKIDQMASRLERSRGWIIKQALTAWVDQEEERNRLTRQAMSDVDDGHVIDHQAVLAWADSLSTDYPLPVPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUL9</accession>
    <name>A0A2S9GUL9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative ATPase (AAA+ superfamily)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3948</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000024">
        <property type="protein sequence ID" value="PRC91403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91403">
        <property type="protein sequence ID" value="PRC91403"/>
        <property type="gene ID" value="S2091_3948"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008533">
        <property type="entry name" value="DUF815"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05673">
        <property type="entry name" value="DUF815"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="2">
        <location>
            <begin position="84"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="189"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="288" mass="32586" checksum="12B07E42519B2E20" modified="2018-07-18" version="1">MEQLEHFLRRAENLISRVEALLPPAIQAPDWELASAFSWRKRSGRGYLQAVRHVAPIQLDDLHQIQIQKQQIEQNTRQFIAGRPANNVLLTGARGTGKSSLIKACLNQFSEQGLRLIEVDKDDLVDLAEIVELVALRPEKFIIFCDDLSFEEGERGYKALKVALDGSISAQSDNVLIYATSNRRHLLPERHSDNSSYHRSEDGDLHPGETVEEKISLSERFGLWVSFYPFKQEDYLDIVAHWLSKLGCSADQIEAARPDALRWALQRGSRSGRVANQFARAFVGEHGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUU3</accession>
    <name>A0A2S9GUU3_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">UPF0056 membrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_3780</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the UPF0056 (MarC) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000022">
        <property type="protein sequence ID" value="PRC91502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91502">
        <property type="protein sequence ID" value="PRC91502"/>
        <property type="gene ID" value="S2091_3780"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002771">
        <property type="entry name" value="Multi_antbiot-R_MarC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33508">
        <property type="entry name" value="PTHR33508"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01914">
        <property type="entry name" value="MarC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00427">
        <property type="entry name" value="TIGR00427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="41"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="71"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="111"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="136"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="175"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC91502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="199" mass="21774" checksum="47F76DF3F8EE8A5D" modified="2018-07-18" version="1">MSQNFFQSFILLILVTDPFGGVPLFVSALSSVPPERRWKVVVRECGIAFLILLLFMFFGRHFLNALQLSDVALRIGGGVILFLIALRMVFPQPGGIFGDIDHSHEPFIVPLAIPALAGPSALATVLLFSSNSNLDVATHVAALVCVAIVWLIVLLSAERMQRLLGERTMTAFERLMGLILTAMSVEMLLAGIHDFIKTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUZ0</accession>
    <name>A0A2S9GUZ0_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Cobalamin biosynthesis protein CobD</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">cobD</name>
        <name evidence="11" type="ORF">S2091_3808</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 10">Cofactor biosynthesis; adenosylcobalamin biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 10">Cell membrane</location>
            <topology evidence="2 10">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the CobD/CbiB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000022">
        <property type="protein sequence ID" value="PRC91530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91530">
        <property type="protein sequence ID" value="PRC91530"/>
        <property type="gene ID" value="S2091_3808"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00148"/>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015420">
        <property type="term" value="F:ABC-type vitamin B12 transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048472">
        <property type="term" value="F:threonine-phosphate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009236">
        <property type="term" value="P:cobalamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00024">
        <property type="entry name" value="CobD_CbiB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031347">
        <property type="entry name" value="AmpE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004485">
        <property type="entry name" value="Cobalamin_biosynth_CobD/CbiB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34308">
        <property type="entry name" value="PTHR34308"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17113">
        <property type="entry name" value="AmpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03186">
        <property type="entry name" value="CobD_Cbib"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00380">
        <property type="entry name" value="cobD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 10" id="KW-0169">Cobalamin biosynthesis</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="53"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="81"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="153"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="289"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC91530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="323" mass="35580" checksum="DF3A167C30318EF3" modified="2018-07-18" version="1">MLIGLSMPAIAWMLLAGVILDLVYGELPRWHPLVGFGRWATWVEQRLNRQRHLILRGLLAWIIVVLPLVGLVFLISKQDDFAWLGHIILLYFCIGLRSLRDHNLPILMALKNQDLEQARQLTSRIVSRDTANATAADLAKASTESMLENGNDAVFGTLFWFVLAGGAGALLFRLANTLDAMWGYRNARFNYFGRVAARVDDVMNWIPARLTALSYVLLAPTYLDKRCAWHCWRSQAPNWPSPNAGPVMASGAGALGLALGGTADYGGITEQRPSLGEGRAAQGEDILRAWHLVLTTTVLWLAIALAAGAVFFVYGGMDGQFYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUZ5</accession>
    <name>A0A2S9GUZ5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Periplasmic binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3811</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000022">
        <property type="protein sequence ID" value="PRC91533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91533">
        <property type="protein sequence ID" value="PRC91533"/>
        <property type="gene ID" value="S2091_3811"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002491">
        <property type="entry name" value="ABC_transptr_periplasmic_BD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01497">
        <property type="entry name" value="Peripla_BP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50983">
        <property type="entry name" value="FE_B12_PBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe/B12 periplasmic-binding" evidence="2">
        <location>
            <begin position="6"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="112"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="266" mass="29299" checksum="951A9370C733BF5C" modified="2018-07-18" version="1">MSHYHRIACLCTESVETLYALGAEDCIAGISGFTVRPPRAREEKPKISGFSSSKLERILAVNPDLVIGFCNLQADICRDLAHAGVEVHLFNQRTVAGILHMIGVLAALVQRQEAGQQLIADLQMQIDQARAQAAQWTRRPVIYFEEWNDPLMSGIGWASEVITIAGGVDAFPELALHASAKQRIIADPDEVVRRAPDIIIGSWCGKKFQAESLCARPGWAEIPAVKNKMIFEIKSPDILSPGPSVIYQGLRQISSFVERWQGLELA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVA2</accession>
    <name>A0A2S9GVA2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Acyl-CoA hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_3744</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the acyl coenzyme A hydrolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000021">
        <property type="protein sequence ID" value="PRC91628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91628">
        <property type="protein sequence ID" value="PRC91628"/>
        <property type="gene ID" value="S2091_3744"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016790">
        <property type="term" value="F:thiolester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040170">
        <property type="entry name" value="Cytosol_ACT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033120">
        <property type="entry name" value="HOTDOG_ACOT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006683">
        <property type="entry name" value="Thioestr_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11049">
        <property type="entry name" value="PTHR11049"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03061">
        <property type="entry name" value="4HBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51770">
        <property type="entry name" value="HOTDOG_ACOT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HotDog ACOT-type" evidence="4">
        <location>
            <begin position="14"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC91628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="139" mass="15205" checksum="FBF21FE0AB55A909" modified="2018-07-18" version="1">MNTSNNPSTQTPLPSRMPQLRVMPMPADANIHGDVFGGWIMAQVDIAGAIPAARRSNGRVATIAVNSFLFKQPVFVGDLLSFYADVVKVGRTSITISVEVYAERNRLEADTVKVTEAMLTYVATDDDRKPRIIPDLVTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVA9</accession>
    <name>A0A2S9GVA9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3712</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000021">
        <property type="protein sequence ID" value="PRC91596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91596">
        <property type="protein sequence ID" value="PRC91596"/>
        <property type="gene ID" value="S2091_3712"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="227"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="256" mass="28987" checksum="E97B918D9350CF1D" modified="2018-07-18" version="1">MSLPALIQAQNLIKAGDIVGAESALATLAETEGDQALVVALDQFPAKDLLAIIREYDCSKESLVNLLVTPAQFAQAVVLEKRYADLSHEQLRGMINSVIFREDADPSEFLYAISEVDGGYDALADYLAERTERIEFFYRYATFDLFEYSDEVKTQAIDDDLLNLTRESEPQSSPLDMSNVEDHDWMEVTTILRYQHPDIFREVLLKLRARLKKENAQHDAFMENMGELPEGVLDNDKPMPSTERPDFEGLQEESAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVC8</accession>
    <name>A0A2S9GVC8_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Sulfur carrier protein FdhD</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">fdhD</name>
        <name evidence="4" type="ORF">S2091_3599</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the FdhD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000020">
        <property type="protein sequence ID" value="PRC91661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91661">
        <property type="protein sequence ID" value="PRC91661"/>
        <property type="gene ID" value="S2091_3599"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097163">
        <property type="term" value="F:sulfur carrier activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016783">
        <property type="term" value="F:sulfurtransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006777">
        <property type="term" value="P:Mo-molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00187">
        <property type="entry name" value="FdhD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003786">
        <property type="entry name" value="FdhD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30592">
        <property type="entry name" value="PTHR30592"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02634">
        <property type="entry name" value="FdhD-NarQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015626">
        <property type="entry name" value="FdhD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="SSF53927"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00129">
        <property type="entry name" value="fdhD_narQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 3" id="KW-0501">Molybdenum cofactor biosynthesis</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Cysteine persulfide intermediate" evidence="3">
        <location>
            <position position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC91661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="288" mass="31151" checksum="AF57FE6373A67355" modified="2018-07-18" version="1">MQNENPDTSLDNNKDGGYGEVPIQRYKDNAFTSSTDFVATEVPVAMVFNGISHAVMLATPLNLTDFAIGFSFSEGIISHRSEVYEIEEIAHPDLGLEIHLTIANACFMRLKERRRSLVGRTGCGICGLESLSAFEAGNLAVGSAVPRLPENNFIITQQALFSAFNSLKQSQAINLITGSMHAAAWVNAQGEVMMVREDLGRHNALDKLIGAIISQPESRQQGCVLMTSRASYELVQKAARAGMPLLAAISAPTSLAINLAQQSGMTLIGFVRNEGLVAYAHPERIRLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVE5</accession>
    <name>A0A2S9GVE5_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Polyribonucleotide nucleotidyltransferase</fullName>
            <ecNumber evidence="8">2.7.7.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Polynucleotide phosphorylase</fullName>
            <shortName evidence="8">PNPase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">pnp</name>
        <name evidence="10" type="ORF">S2091_3640</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>phosphate + RNA(n+1) = a ribonucleoside 5'-diphosphate + RNA(n)</text>
            <dbReference type="Rhea" id="RHEA:22096"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57930"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the polyribonucleotide nucleotidyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.8" evidence="8"/>
    <dbReference type="EMBL" id="PUGF01000020">
        <property type="protein sequence ID" value="PRC91702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91702">
        <property type="protein sequence ID" value="PRC91702"/>
        <property type="gene ID" value="S2091_3640"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004654">
        <property type="term" value="F:polyribonucleotide nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006402">
        <property type="term" value="P:mRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.70">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01595">
        <property type="entry name" value="PNPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001247">
        <property type="entry name" value="ExoRNase_PH_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015847">
        <property type="entry name" value="ExoRNase_PH_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036345">
        <property type="entry name" value="ExoRNase_PH_dom2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004088">
        <property type="entry name" value="KH_dom_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012162">
        <property type="entry name" value="PNPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027408">
        <property type="entry name" value="PNPase/RNase_PH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015848">
        <property type="entry name" value="PNPase_PH_RNA-bd_bac/org-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036456">
        <property type="entry name" value="PNPase_PH_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022967">
        <property type="entry name" value="S1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11252">
        <property type="entry name" value="PTHR11252"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00013">
        <property type="entry name" value="KH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03726">
        <property type="entry name" value="PNPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01138">
        <property type="entry name" value="RNase_PH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03725">
        <property type="entry name" value="RNase_PH_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00575">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005499">
        <property type="entry name" value="PNPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46915">
        <property type="entry name" value="SSF46915"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="SSF54791"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55666">
        <property type="entry name" value="SSF55666"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03591">
        <property type="entry name" value="polynuc_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 8" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 8 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="S1 motif" evidence="9">
        <location>
            <begin position="620"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="484"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="490"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01595"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC91702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="712" mass="76344" checksum="220D1FB41B04D157" modified="2018-07-18" version="1">MFNKITKTFQYGQHQVTLETGEIARQATGAVLVSIEDTVVLATVVARKDAKPGQDFFPLTVDYLEKTYAAGRIPGGFFKREGRPSEKETLTSRLIDRPIRPLFPEGYLNEVQVVIHVLSVNPEIDPDIAAMIGASAALCVSGIPFNGPLGAARVGYIDGQYVLNPSPTQLKTSMMDLVVAGTESAVLMVESDAKQLSEEIMLGGVVFGHTEMRVVIDAIHDLVEQGGKPEVEWAPAPKNEALIASVGAVAEPLLRAAYQIKEKQARTEKLKSATAAVNAALVGQDVDSVELGNIMFDLESKIVRSQILDGEPRIDGRDTRTVRPISIRTGVLPRTHGTALFTRGETQALVIATLGTSRDEQKIDALMGEYSDRFMLHYNMPPFATGETGRVGTPKRREIGHGRLAKRALEAVLPDVADFSYSVRLVSEITESNGSSSMASVCGGCLALMDAGVPVKAHVAGIAMGLIKDGNKFAVLTDILGDEDHLGDMDFKVAGTANGITALQMDIKIQGITKEIMQVALAQAKEGRLHILEKMQTAVPHGNVELSDFAPRLITIKINPEKIRDVIGKGGAVIRALTEETGTQIDISDEGVVTIASVDAAAGQEARRRIQEITAEVEVGKVYEGTVLKLLDFGAIVQVLPGKDGLLHISQIANERVNAVADYLKEGQVVRVKVLETDDRGRLKLSMKAAASESEVSVAPAAVVAEAGQVEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVE7</accession>
    <name>A0A2S9GVE7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Outer membrane protein W</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3619</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000020">
        <property type="protein sequence ID" value="PRC91681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91681">
        <property type="protein sequence ID" value="PRC91681"/>
        <property type="gene ID" value="S2091_3619"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011250">
        <property type="entry name" value="OMP/PagP_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005618">
        <property type="entry name" value="OMPW"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36920">
        <property type="entry name" value="PTHR36920"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03922">
        <property type="entry name" value="OmpW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56925">
        <property type="entry name" value="SSF56925"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015460834" evidence="2">
        <location>
            <begin position="22"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="247" mass="25711" checksum="E815C42C24B80EE2" modified="2018-07-18" version="1">MQFQITSAAKFAALAILAASAAPSFAQSAGDTVVSAGWAHIAPQDSSTPLVITSPNIPGVAGPKVGSGASVDPTNTLEVSIDRFLTDNWVASLDIGVPPTYKLIGTGTFAPIGQIGTAKQWAPALLGKYYFGTAQTAFRPILGLGIAHVSYSDVSLSNSFQTYGQQQGFDSSAVSTAKLGSSWVPVFNAGASYAIDKDWYASFTVSYVKLKTTADLTINPTLVGSVQGNTTLTLNPIVLYAAIGYRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVM5</accession>
    <name>A0A2S9GVM5_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">UPF0229 protein S2091_3532</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3532</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0229 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000019">
        <property type="protein sequence ID" value="PRC91777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91777">
        <property type="protein sequence ID" value="PRC91777"/>
        <property type="gene ID" value="S2091_3532"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01232">
        <property type="entry name" value="UPF0229"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006698">
        <property type="entry name" value="UPF0229"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30510">
        <property type="entry name" value="PTHR30510"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04285">
        <property type="entry name" value="DUF444"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="SSF53300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="82"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="424" mass="48716" checksum="52B217EA859C939A" modified="2018-07-18" version="1">MVHLIDRRIQGKNKSAVNRERFLRRYKDQIKEAVTRAVKGRSITNVESGEKISIPVRDVNEPSFGHDHGGVWETVRPGNKEYLKGDQFKRPKGGAGSGKGQAGNSEETSEDDFVFEVSREEFMNYFFEDLELPNMVKTQLTASTDFKQLRAGYKMSGTTTNLHVLRSLRGALSRRIAVGGKSSRRIKLAEQELRALLDEGVSVDDDRVLLLRHEITHLRTRLLAIPFLDTFDLRYSNRIKVPKPSSQAVMFCILDVSGSMDEAKKDTAKRFFILLYLFLTRSYEKIELVFIRHHTTAMEVDEQEFFNSRESGGTVVSSAINLLNTILRDRYPTGEWNAYVAQASDGDNWDNDSITCRQLLMDTTLPLVQYYAYVEITDGEPQNLWREYEQIASYHSHFAMRKIEDPSDIYPVFRDLFKKQNAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVP7</accession>
    <name>A0A2S9GVP7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">GGDEF: diguanylate cyclase (GGDEF) domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3535</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000019">
        <property type="protein sequence ID" value="PRC91780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91780">
        <property type="protein sequence ID" value="PRC91780"/>
        <property type="gene ID" value="S2091_3535"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="41"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="67"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="93"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="2">
        <location>
            <begin position="156"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="289" mass="31806" checksum="F910035DEDECC836" modified="2018-07-18" version="1">MKKIFSSYLKRIASPGFISEGFAITASYLAILILFPFDINTSSQVSLHVLYVFPLTLIALHCSRSNLVIGAAALSITLQAIALWMPSEVSFTIKIYLFLMIVLSNSTFVLVARFARTNIIEAERLSTIDPLTKLSNRRALEIAIDAEIVRQRRYGGYFSVVLIDLDGFKGLNDSLGHHAGDRALIMLADILRDHTRQSDTISRIGGDEFVILMPNTQAADCEALCQTLCHKITHSMAEVSFLITASIGYTTIEQAPEISKDVIAIADRAMYTAKSSGKGRVVRGYSSSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVS3</accession>
    <name>A0A2S9GVS3_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peptidoglycan hydrolase FlgJ</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Muramidase FlgJ</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">S2091_3378</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">In the C-terminal section; belongs to the glycosyl hydrolase 73 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">In the N-terminal section; belongs to the FlgJ family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000018">
        <property type="protein sequence ID" value="PRC91822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91822">
        <property type="protein sequence ID" value="PRC91822"/>
        <property type="gene ID" value="S2091_3378"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004040">
        <property type="term" value="F:amidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016798">
        <property type="term" value="F:hydrolase activity, acting on glycosyl bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044780">
        <property type="term" value="P:bacterial-type flagellum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008152">
        <property type="term" value="P:metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019301">
        <property type="entry name" value="Flagellar_prot_FlgJ_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013377">
        <property type="entry name" value="FlaJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002901">
        <property type="entry name" value="MGlyc_endo_b_GlcNAc-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01832">
        <property type="entry name" value="Glucosaminidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10135">
        <property type="entry name" value="Rod-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00047">
        <property type="entry name" value="LYZ2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02541">
        <property type="entry name" value="flagell_FlgJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0966">Cell projection</keyword>
    <keyword evidence="11" id="KW-0969">Cilium</keyword>
    <keyword evidence="11" id="KW-0282">Flagellum</keyword>
    <keyword evidence="7" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0574">Periplasm</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LYZ2" evidence="10">
        <location>
            <begin position="141"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="111"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00030835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC91822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="297" mass="31844" checksum="6E1A529752DB890C" modified="2018-07-18" version="1">MTTPIDGTEKLAVDANSLNDLRRATNQNSPAGVKAAAKQFEALFVGMMLKSMRKAMPQDGPFDTEQSKMFTSMLDEQLSQKIAARGLGLAAVLEKQMLNNAALQYTSKHSTSVANPVPTSEADPTSITQHAQSLKAASPGLSNSQAQVQAFQHKLSGYAQQASQATGIPANFMLGQAALESGWGKHEIATTNGQPSHNLFGIKAGKNWTGKVVTAVTTEYCNGVATQKVEKFRCYNNYGEAFNDYANLLQGNQRYKNVLANAKDAYGFAQGLQKAGYASDPEYANKLMSVIAKTSST</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GW21</accession>
    <name>A0A2S9GW21_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">ATP synthase subunit b</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">ATP synthase F(0) sector subunit b</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">ATPase subunit I</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">F-type ATPase subunit b</fullName>
            <shortName evidence="13">F-ATPase subunit b</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">atpF</name>
        <name evidence="15" type="ORF">S2091_3267</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.</text>
    </comment>
    <comment type="function">
        <text evidence="11 13">F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="13">F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="13">Cell membrane</location>
            <topology evidence="13">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the ATPase B chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000017">
        <property type="protein sequence ID" value="PRC91925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91925">
        <property type="protein sequence ID" value="PRC91925"/>
        <property type="gene ID" value="S2091_3267"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045263">
        <property type="term" value="C:proton-transporting ATP synthase complex, coupling factor F(o)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01398">
        <property type="entry name" value="ATP_synth_b_bprime"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017707">
        <property type="entry name" value="Alt_ATP_synth_F0_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002146">
        <property type="entry name" value="ATP_synth_b/b'su_bac/chlpt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00430">
        <property type="entry name" value="ATP-synt_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03321">
        <property type="entry name" value="alt_F1F0_F0_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 13" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="13" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 13" id="KW-0138">CF(0)</keyword>
    <keyword evidence="6 13" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="8 13" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 13" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="260"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00025198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00025614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01398"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="PRC91925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="311" mass="34636" checksum="66F82FBC062B29BC" modified="2018-07-18" version="1">MLIDWFTVVAQTINFLILVWLMKRYLYQPILNAIDAREAKITAALKDAESKQTAATQQRNEFQKKNDTFEQGRSALLQAAQDDAKTERKKMLDQTRKDVDVLRTKLEATLQGEHDALKREVTIGVQEEVFSIARRVLSDLGSASVETQIIKVFIDRLRTLDEHAKTELTKALKNSTEPALVRSAFALSEGQQKAIQLALKETFAMEAPVKFDIAPRLVCGVELSINGQKLAWSIDDYLTSLDKRINDIVTPAVKAETNVDAKTGAETEAKTEDAPTIIPMTEAQIQANETADPTEPFKDEPDTVTTDSASK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWC7</accession>
    <name>A0A2S9GWC7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative ester cyclase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3340</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000017">
        <property type="protein sequence ID" value="PRC91998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91998">
        <property type="protein sequence ID" value="PRC91998"/>
        <property type="gene ID" value="S2091_3340"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030638">
        <property type="term" value="P:polyketide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009959">
        <property type="entry name" value="Cyclase_SnoaL-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38436">
        <property type="entry name" value="PTHR38436"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07366">
        <property type="entry name" value="SnoaL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="150" mass="16608" checksum="FA879E0A671CF022" modified="2018-07-18" version="1">MYTMSQPSQLDANTALVTKFMQDVWNRQDAAAVPNFVTTDYIDHAYTPRDASGHAAMVGAFSAAFSDAQHVIEQLTAQDDYVVIRVRVTARHTGNFRDAAPSGNLIDVVQYRTFRLLDNKIAEHWALFDTATLFRQIGASPSPANACVKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWD1</accession>
    <name>A0A2S9GWD1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">PhnA: putative alkylphosphonate utilization operon protein PhnA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_3172</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the YjdM family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000016">
        <property type="protein sequence ID" value="PRC92037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92037">
        <property type="protein sequence ID" value="PRC92037"/>
        <property type="gene ID" value="S2091_3172"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004624">
        <property type="entry name" value="YjdM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013988">
        <property type="entry name" value="YjdM_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013987">
        <property type="entry name" value="YjdM_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30305:SF3">
        <property type="entry name" value="PTHR30305:SF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03831">
        <property type="entry name" value="YjdM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08274">
        <property type="entry name" value="YjdM_Zn_Ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00686">
        <property type="entry name" value="phnA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YjdM_Zn_Ribbon" evidence="3">
        <location>
            <begin position="3"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="domain" description="YjdM" evidence="2">
        <location>
            <begin position="48"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC92037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="114" mass="12304" checksum="490B62EF5A365594" modified="2018-07-18" version="1">MSTLPPCPQCNSEFTYEDGGQYVCPECAHEWSAQAAAATADEGKRVYRDSAGNELQDGDTVSVIKDLKLKGSGGVVKMGTKVKNIRLVDSDHDIDCKIDGFGAMSLKTEFVKKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWH7</accession>
    <name>A0A2S9GWH7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">/NonD: hydrolase CocE/NonD family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3222</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000016">
        <property type="protein sequence ID" value="PRC92087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92087">
        <property type="protein sequence ID" value="PRC92087"/>
        <property type="gene ID" value="S2091_3222"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008239">
        <property type="term" value="F:dipeptidyl-peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005674">
        <property type="entry name" value="CocE/Ser_esterase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000383">
        <property type="entry name" value="Xaa-Pro-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013736">
        <property type="entry name" value="Xaa-Pro_dipept_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02129">
        <property type="entry name" value="Peptidase_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08530">
        <property type="entry name" value="PepX_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00939">
        <property type="entry name" value="PepX_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="SSF49785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00976">
        <property type="entry name" value="NonD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015461794" evidence="1">
        <location>
            <begin position="24"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="domain" description="PepX_C" evidence="2">
        <location>
            <begin position="372"/>
            <end position="638"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="645" mass="71728" checksum="170595A5D5F8C204" modified="2018-07-18" version="1">MTHFLLRSAISLALMTLANAAYADTAPTPFLTPDIPQSFVAPKLGYNYEKRVVMIPMRDGVKLYTVIVVPKGAKNAPILLTRTPYNAAKKAAREDSPNMLAAMPPSDDVFVAGGYIRVFQDVRGKHGSEGDYVMTRPLRGVLNSSTVDHSTDAYDTIDYLVKNIPESNGKVGMIGSSYEGFTVVMALIHPHPALKVAAPESPMVDGWMGDDWFHHGAFRQTNFDYIAGQTTARGEGKSIARQGSDDYENFRRAGSAGAYATAAGLNQLPFWLKLSEHPGYDQYWQEQALDKIMARQPLTVPTMWLQGLWDQEDMWGAIHSYFATEPKDTANDKNFLVMGPWRHSGVNFDGSTLGPLKFDGDTALQFRRDVLRPFFDQYLKDGAPKANTPPVFIYNTGENHWDRLKAWPLSCEVNCEFKSKPIYLTAGGTLSFTAPTETHGAAAFDEYISDPAKPVPYLARPVRFADSNAWKQWLVTDQRAFTDRTDVLSYSTEPLTAPVKISGTPMVNLVASTSGTDSDWVVKLIDVFPDSVADQPSMGGYELAVGMDIFRGRYRESFTNPKAITPNKPLTYKFILPSANHTFLPGHRIMVQVQSSWFPLYDRNPQTFVPNIFFANPSDYVKATQRIYHAQNSASYISLPVAPVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWL5</accession>
    <name>A0A2S9GWL5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_3247</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000016">
        <property type="protein sequence ID" value="PRC92112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92112">
        <property type="protein sequence ID" value="PRC92112"/>
        <property type="gene ID" value="S2091_3247"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000485">
        <property type="entry name" value="AsnC-type_HTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019888">
        <property type="entry name" value="Tscrpt_reg_AsnC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019887">
        <property type="entry name" value="Tscrpt_reg_AsnC/Lrp_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01037">
        <property type="entry name" value="AsnC_trans_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00033">
        <property type="entry name" value="HTHASNC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00344">
        <property type="entry name" value="HTH_ASNC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50956">
        <property type="entry name" value="HTH_ASNC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH asnC-type" evidence="4">
        <location>
            <begin position="7"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC92112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="169" mass="19307" checksum="DA57DDADB3405005" modified="2018-07-18" version="1">MSKQHVLDKVDRKILNLLQKDNQIATRVLAEKVHISQPTCLRRIRDMRQAGVISADVSMVDPFALGYGMLAFLEVSLSNQSEESMTAFEQRMAKEGQVMQCYFVSGEYDYFVVVHVIDMDAYYQFVRKVISGSGNVKHFHSRFPMKCAKFSTRIGFDEKAAEVVVRKAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWQ4</accession>
    <name>A0A2S9GWQ4_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ribosome-recycling factor</fullName>
            <shortName evidence="3">RRF</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Ribosome-releasing factor</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">frr</name>
        <name evidence="5" type="ORF">S2091_3065</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the RRF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92149">
        <property type="protein sequence ID" value="PRC92149"/>
        <property type="gene ID" value="S2091_3065"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006415">
        <property type="term" value="P:translational termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00520">
        <property type="entry name" value="RRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00040">
        <property type="entry name" value="RRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002661">
        <property type="entry name" value="Ribosome_recyc_fac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023584">
        <property type="entry name" value="Ribosome_recyc_fac_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036191">
        <property type="entry name" value="RRF_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20982">
        <property type="entry name" value="PTHR20982"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01765">
        <property type="entry name" value="RRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55194">
        <property type="entry name" value="SSF55194"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00496">
        <property type="entry name" value="frr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 3" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RRF" evidence="4">
        <location>
            <begin position="22"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC92149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="186" mass="21173" checksum="738F2D948CF1226E" modified="2018-07-18" version="1">MAVVDVRKNTELRMQKSLEALRADLAKVRTGRAHTGILDHVQVDYYGNPTQLTQVANVTLIDARTIGVQPWEKKMVAVVEKAIRDSDLGLNPSTQGDMIRVPTPPLTEERRKEFVKLVKTEGEDAKIAVRNIRRDANEAFKKMLKDKECSEDDERRAQDDVQKLTDKFVLDVDKMVSEKEKELLTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GX81</accession>
    <name>A0A2S9GX81_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glycosyl hydrolase family 3 N terminal domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_2982</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92323">
        <property type="protein sequence ID" value="PRC92323"/>
        <property type="gene ID" value="S2091_2982"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001764">
        <property type="entry name" value="Glyco_hydro_3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036962">
        <property type="entry name" value="Glyco_hydro_3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00933">
        <property type="entry name" value="Glyco_hydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="1 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyco_hydro_3" evidence="3">
        <location>
            <begin position="5"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC92323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="512" mass="54996" checksum="EBBB742DDEE95C68" modified="2018-07-18" version="1">MNQELRKKIGQLFMVGFDALEVNPHITRQIQEQKVGGIILFRRNVQSPEQVAALCRNLQEINAAVSDIPLLISIDQEGGMVMRVEQGVTPIPAAMAFQAAGSVQECEQLSRISGDEMRQIGINMILAPVLDVNNNPLNPVIGVRAYGEDPDTVIKYGMAAMRGLQSAGVITTAKHFPGHGDTSTDSHYSMSLVPHGRERLDAMELPPFNAAIAQGVHAIMTAHVVFPAIESEPDLPATLSKAVLTDLLRGELKFNGVIISDCLEMAAISDGVGVTQGALATLQAGADIALISHLEARQQVAIDAVVEAALSGTISMERIDDAYQRVQQLKQITAVSEWRNAPIKPVGLMQPEALALAKKVQKAALRVQGDFRPLNLQLPVTLITLEVRLRSEVDEAVVARNKEARSSMLPALLEAGVNVREFALSSEAKDADVAAAIAFAEGAQQIVLQTYNAMLVLGQQQLLAALPHDKMWLVAGRLPYDLDLAPNAQGRLAAYGCRPAALTPVVEKLIGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GX91</accession>
    <name>A0A2S9GX91_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">LysE type translocator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_2992</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92333">
        <property type="protein sequence ID" value="PRC92333"/>
        <property type="gene ID" value="S2091_2992"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001123">
        <property type="entry name" value="LeuE-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30086">
        <property type="entry name" value="PTHR30086"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01810">
        <property type="entry name" value="LysE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015466626" evidence="6">
        <location>
            <begin position="18"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="44"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="76"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="118"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="143"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="184"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC92333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="206" mass="21802" checksum="210089C858AC7095" modified="2018-07-18" version="1">MNEFLTVVLSMSSFAFATSASPGPVNIVAAMSGAEFGIKRSYGFVLGATIGFVAILLGVGIGIGHTLASNKTISNSLAIAGSIYMLYLSYQLATSKPSKSELTTIPAPRFISGAVAQWLNPKAWIVSISAISIYVANSSNYTLYLSIFGAIFFIVCFLSILGWVIMGSKASALLNGNYSVFNKIMAGLLVLSVTYFLVQFVIFGKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXG1</accession>
    <name>A0A2S9GXG1_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 11">Pyruvate kinase</fullName>
            <ecNumber evidence="3 11">2.7.1.40</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">S2091_2778</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>ATP + pyruvate = ADP + H(+) + phosphoenolpyruvate</text>
            <dbReference type="Rhea" id="RHEA:18157"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.40"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 11">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 5/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the pyruvate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.40" evidence="3 11"/>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92403">
        <property type="protein sequence ID" value="PRC92403"/>
        <property type="gene ID" value="S2091_2778"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00188"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030955">
        <property type="term" value="F:potassium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004743">
        <property type="term" value="F:pyruvate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.33.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1380.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001697">
        <property type="entry name" value="Pyr_Knase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_Kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011037">
        <property type="entry name" value="Pyrv_Knase-like_insert_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015793">
        <property type="entry name" value="Pyrv_Knase_brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015795">
        <property type="entry name" value="Pyrv_Knase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036918">
        <property type="entry name" value="Pyrv_Knase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015806">
        <property type="entry name" value="Pyrv_Knase_insert_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11817">
        <property type="entry name" value="PTHR11817"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00224">
        <property type="entry name" value="PK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02887">
        <property type="entry name" value="PK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01050">
        <property type="entry name" value="PYRUVTKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50800">
        <property type="entry name" value="SSF50800"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="SSF51621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52935">
        <property type="entry name" value="SSF52935"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01064">
        <property type="entry name" value="pyruv_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 11" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="6 11 14" id="KW-0418">Kinase</keyword>
    <keyword evidence="8 11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10 14" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PK" evidence="12">
        <location>
            <begin position="3"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="domain" description="PK_C" evidence="13">
        <location>
            <begin position="360"/>
            <end position="472"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="PRC92403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="476" mass="51850" checksum="EF01DD3DB4CE03CF" modified="2018-07-18" version="1">MYRGTKIVATVGPASNTVEILTRMLQAGVNVVRLNFSHGKAQDHIDRAAMVREAALSCGREVAIMADLQGPKIRIGKFENGKIELQNGEKFILDAECTLGNQGRVGLDYKALPRDVKPNDLLLLNDGLIVLVVDKIVGAEIFTTVKIGGELSNNKGINRQGGGLTAPALTSKDMEDIKTAMSFQADYLAVSFPKNATDMEMARQLANIAGEPYNHKPMMIAKIERAEAIPLLQEILNASDGIMVARGDLAVEVGNATVPALQKRMIKMARASNKLTITATQMMESMIFNAVPTRAEVSDVANAVLDGTDAVMLSAETASGKYPVETVEMMAAVCFEAEKSYECELDADFLNARFTRIDQSIAYGALFTAYHLRVKAIVALTESGSTTLWMSRHNIDIPLIALTPSRTTQRKIALYRNVRTYELPYHCDKDTMLNNVEQILLDNNVVQKGDTIVVTWGEPMGQVGGTNALRIVRVGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXH0</accession>
    <name>A0A2S9GXH0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2790</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92415">
        <property type="protein sequence ID" value="PRC92415"/>
        <property type="gene ID" value="S2091_2790"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015749095" evidence="2">
        <location>
            <begin position="20"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="121"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="144" mass="16787" checksum="D4F3FA27ACEA6A06" modified="2018-07-18" version="1">MNRFLISLALLASPLLANAGPNVGVSVNIGQPGFYGQIELGNVPPPPVMYGTPMIIQPAPVGVVVQPLYLRVPSSHYRNWRHYCGRYNACGRPVYFVQDNWYRNTYAPQYRHEHEGRGYEHRDYDHHDHDRHDDRHEDRHDDRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXI0</accession>
    <name>A0A2S9GXI0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Putative metalloendopeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">S2091_2786</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92411">
        <property type="protein sequence ID" value="PRC92411"/>
        <property type="gene ID" value="S2091_2786"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08662">
        <property type="entry name" value="M13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1380.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000718">
        <property type="entry name" value="Peptidase_M13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018497">
        <property type="entry name" value="Peptidase_M13_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042089">
        <property type="entry name" value="Peptidase_M13_dom_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008753">
        <property type="entry name" value="Peptidase_M13_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11733">
        <property type="entry name" value="PTHR11733"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01431">
        <property type="entry name" value="Peptidase_M13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05649">
        <property type="entry name" value="Peptidase_M13_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00786">
        <property type="entry name" value="NEPRILYSIN"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51885">
        <property type="entry name" value="NEPRILYSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015616585" evidence="8">
        <location>
            <begin position="25"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M13_N" evidence="10">
        <location>
            <begin position="58"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M13" evidence="9">
        <location>
            <begin position="490"/>
            <end position="691"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF05649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC92411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="694" mass="77138" checksum="A44F75CD3640205B" modified="2018-07-18" version="1">MQRTLLSIAVLAAISVGGANLSYAQTPAPISATLNKTSNIAAINSGIDLQWLDTSVRPQNDFFQYMSGKWLATVEIPADRARFGSFDQLRDLSEERSHSIIDELVAEPHKKIGSNEQKIADLYSSYMDEAHADKLDIKPLHATFARIDGLTKKEQLPALISELSKLGVSLPVQSNVGQDARDSSKYAVYVGQGGLGLPDRDYYLKDDDAKLKGFRDAYVKHVEKMLAMSGQKDADKSAAEILALETALAKIQWSKVENRNPVKTYNKVEIAKLAELLPNFDWNAYFVGTGVGNKVAYVIVRQPDFISGLTKIINDTPVAVWKTYYKWKVLDAYASLLSKRFVDQDFAFTSVTLRGIPENLPRWKRGVARVEDNLSEALGQLYVQKYFPPENKARMEKLVSNLTLAYKQSIETLDWMSPETKKEALIKLSKFTAKIGYPDQWRDYSKLEIKKDDLVGNVMRGRAFEHQRQLSKLGKPVDTKEWSMSPQTVNAYYNSRRNEIVFPAAILQPPFFNPAADDAVNYGGIGAVIGHEISHGFDDSGSQSDGDGNLRDWWTKEDKANFGKLTAAMTAQYSAYSPLPGYNVNGALTLGENIADNSGLSIAYKAYQISLGGKPAPVIDGYTGEQRLYMGWGQVWRGKAREAETIRLINTDPHSPAAVRGNATLTNQPGFYSAFGVKEGDAMYVAPEKRITIW</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXI1</accession>
    <name>A0A2S9GXI1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_2793</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92418">
        <property type="protein sequence ID" value="PRC92418"/>
        <property type="gene ID" value="S2091_2793"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006603">
        <property type="entry name" value="PQ-loop_rpt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04193">
        <property type="entry name" value="PQ-loop"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="40"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="65"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC92418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="87" mass="9660" checksum="5A5008501E6B0331" modified="2018-07-18" version="1">MTHLNYADLVGYLAASLTTTAFIPQAWLTWKNKHADGVSLGMYVIFTVGIALWLCYGILIQVWPIIISNAITLLLAGFILAMKIIYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXP4</accession>
    <name>A0A2S9GXP4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2872</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92497">
        <property type="protein sequence ID" value="PRC92497"/>
        <property type="gene ID" value="S2091_2872"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="88" mass="10005" checksum="56100809D770D027" modified="2018-07-18" version="1">MLNMKICEICGSILEECGTCLFNVPEDKAPCLADYEAMARGEMSHAEHQIVVGRWALHNTELQSQKTLIKMREFADSAWGKKVKIFKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXX3</accession>
    <name>A0A2S9GXX3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">AhpC/TSA family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_2629</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92574">
        <property type="protein sequence ID" value="PRC92574"/>
        <property type="gene ID" value="S2091_2629"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016209">
        <property type="term" value="F:antioxidant activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000866">
        <property type="entry name" value="AhpC/TSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
        <property type="entry name" value="AhpC-TSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015418988" evidence="2">
        <location>
            <begin position="31"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="3">
        <location>
            <begin position="133"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC92574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="276" mass="30644" checksum="2216B3074480FABA" modified="2018-07-18" version="1">MRHHFTFTLLKLLNVAAALFFVLASVNTHAMSDTPPANPIPPAASKDSIDTTTTPANAENKIREKLMLKKIQTITYQDKKGNALTADEFLKRIDAGESYQAVKKFMTDGPSSAVLSLVDKDLAPKPFKTKYNIKIGDKFPSFHLKQLDGSFVDNQHLMGRYTLFNFFFSECAPCIKEIPDLNSLALKNQSMNFVAMTFDSNSDAQQFVVDTNFKWKIVPDSTKFIDKVGVNTFPAFVLIDPRGVVVGIASVVDFDGADKNLSNWVNHLAVNLTAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXZ4</accession>
    <name>A0A2S9GXZ4_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Phosphoserine phosphatase</fullName>
            <ecNumber evidence="6">3.1.3.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">O-phosphoserine phosphohydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">S2091_2652</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>H2O + O-phospho-D-serine = D-serine + phosphate</text>
            <dbReference type="Rhea" id="RHEA:24873"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:35247"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58680"/>
            <dbReference type="EC" id="3.1.3.3"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H2O + O-phospho-L-serine = L-serine + phosphate</text>
            <dbReference type="Rhea" id="RHEA:21208"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57524"/>
            <dbReference type="EC" id="3.1.3.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Amino-acid biosynthesis; L-serine biosynthesis; L-serine from 3-phospho-D-glycerate: step 3/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the HAD-like hydrolase superfamily. SerB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.3" evidence="6"/>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92597">
        <property type="protein sequence ID" value="PRC92597"/>
        <property type="gene ID" value="S2091_2652"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00135">
        <property type="reaction ID" value="UER00198"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036424">
        <property type="term" value="F:L-phosphoserine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006564">
        <property type="term" value="P:L-serine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004469">
        <property type="entry name" value="PSP"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00029">
        <property type="entry name" value="phosphoserine_phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00338">
        <property type="entry name" value="serB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0718">Serine biosynthesis</keyword>
    <feature type="active site" description="Nucleophile" evidence="14">
        <location>
            <position position="82"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="14">
        <location>
            <position position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001197"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00009184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00015196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00031693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR604469-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="PRC92597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="282" mass="30710" checksum="66DA40771366D8D7" modified="2018-07-18" version="1">MILILQSLSADIATLHRIGALAEPQQTFEFAPHALRCVGLSFTEHVSVIQEKIATLAFQEQVDVHWINSNHQLADFKLLAMDMDSTLITIECIDEIADMQGLKPQVAAITEAAMRGEIAFAESLTQRVALLKGLPATALQQVYDERLQLSPGAEKMLQAVQAAGLKTLLVSGGFTFFTDRVKSKLNLDYSHSNQLEILDGKLTGRVIGGIVDAEEKRRTVERICAELRILPSQAIVMGDGANDLAMMEIAGLSVAFRAKPVVRAKADIALNFVGLDGILNFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXZ5</accession>
    <name>A0A2S9GXZ5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2636</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92581">
        <property type="protein sequence ID" value="PRC92581"/>
        <property type="gene ID" value="S2091_2636"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021267">
        <property type="entry name" value="DUF2844"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11005">
        <property type="entry name" value="DUF2844"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015456099" evidence="1">
        <location>
            <begin position="20"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="156" mass="16921" checksum="245B2517DC8905DE" modified="2018-07-18" version="1">MLKAWAGLMIAAVSLSAHATLGENASTVSTDQAALHATLTTQVSANYTDYMLTLPDGIVVHEFVNSASKVFEITWSGKRHRPDMQQLLGQYFTRFTDTSHKTRPTTRQAHQVTTELVIHSSAIHGYFSGTAHVPALLPETMTGPVNPVSTSQDVAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GY93</accession>
    <name>A0A2S9GY93_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2747</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92692">
        <property type="protein sequence ID" value="PRC92692"/>
        <property type="gene ID" value="S2091_2747"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="170" mass="18583" checksum="B23D545A6E9B4DC0" modified="2018-07-18" version="1">MSKKKIPTHHSYTRLNRSISGFAYLALLISVALIGIAAVATVQIGSIMQRRAAEEELLAIGSQFQSAFVSYANATPTGQSSAPASLQDLLKDPRYPTIRRHLRKIYIDPLTGKQEWGTVAAIDGSGIIGIYSLSKDGPIKIGNFEPAFQLFEGKTSYREWLFTAPLLIGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GY96</accession>
    <name>A0A2S9GY96_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2752</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92697">
        <property type="protein sequence ID" value="PRC92697"/>
        <property type="gene ID" value="S2091_2752"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="206" mass="23142" checksum="71DF68D0F52E2084" modified="2018-07-18" version="1">MKLTSISQFALKLRLGCRQLGWSNALAILLCLSGSIAWLWAVPYLKQQRMISQTKLQQTQVTVNQLPKATSAVELTQSEQRLRAFYSALGETHYVEQQVASLIGLATKNGLILNQAEYKLAQNKNGHFHTYTVTMPVKGQYSMIRGFCDQVLLSIPFAALDELNFKRASISNQIIETRIRFTLYLDDVSEPENNSLASSVKQGELQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYB2</accession>
    <name>A0A2S9GYB2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Type II secretory pathway component PulF</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_2756</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GSP F family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92701">
        <property type="protein sequence ID" value="PRC92701"/>
        <property type="gene ID" value="S2091_2756"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.81.30">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003004">
        <property type="entry name" value="GspF/PilC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018076">
        <property type="entry name" value="T2SS_GspF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042094">
        <property type="entry name" value="T2SS_GspF_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30012">
        <property type="entry name" value="PTHR30012"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00482">
        <property type="entry name" value="T2SSF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00812">
        <property type="entry name" value="BCTERIALGSPF"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="158"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="219"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="367"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="domain" description="T2SSF" evidence="8">
        <location>
            <begin position="62"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="domain" description="T2SSF" evidence="8">
        <location>
            <begin position="267"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC92701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="395" mass="43379" checksum="D37935381B12EB6A" modified="2018-07-18" version="1">MQFDVRALSSDHVLTLVTIDAIDEVDARRQIEARGLYASDISPARGLRQGKSTKGQLSLVLFSQELLALLNAGLSIVESLEALLEKEANLGTRHILTRLLTGLREGKRFSGVLAEQPNLFTPLYIGIIKAAEGTSDLPRSLTRFIDYQQRINTVRSKVVSAAIYPLILLFVGGGVAFFLIGYVVPRFAEVYRGAGRNLPWMSQLLLDWGQFAATRTTTLLISTALILTALVFLVRYFLKTGGVARLAYRIPGLGERIRIYELARLYLTLGMLLEGGIPIVTAMGTVQGIVSSEMQRHLQQATHSIQSGIPLSNAFEANQLTTSISLRMLRVGERSGELGSMLTQSAAFYDGEISRWIDRFARMFEPILMAIIGIVVGGIVVLLYMPIFDLAGSLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYT1</accession>
    <name>A0A2S9GYT1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">NAD-dependent aldehyde dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_2299</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92882">
        <property type="protein sequence ID" value="PRC92882"/>
        <property type="gene ID" value="S2091_2299"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016620">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
        <property type="entry name" value="ALDEHYDE_DEHYDR_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldedh" evidence="5">
        <location>
            <begin position="31"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="263"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC92882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="493" mass="53085" checksum="8ADCF25BB6E48A25" modified="2018-07-18" version="1">MPLSKQSIFDLARTGQLWAGNIIPNHLTSTARLENFTPIDNSYIGTIEAGTKADMDAAVVAARSAFESGEWSQRPPSERKIVMQNWVTLLEKHAEELAALDCIDAGKPITECLNADLPATISTFAWYAEAIDKCYGRIAPTGPEATGLIVKEAIGVVGAVLPWNFPAQMFAWKVAPALAAGNSVIVKPAELTSLSAYRMVQLAHEAGIPAGALILVTGLGEVVGAALGLHHDVDVVSFTGSTEVGRLFLKYSADSNLKEIILECGGKSPQIVFEDAPLDEIVNDVLAAAFWNMGENCSCGSRLIVHSSIKQKLISKLTQGLESWQVGLPTDPATKIGPMIEKAHFEKVKHFLDTAQAEGAKLVHGGRVHSKIGGGWYIEPTIYDEVTPAMRLFQEEIFGPILAVTSFDTEQQALQLANDSQYGLAASLYTMDIKRAARMARGIRAGTVSINGFSEGDITTPFGGYKQSGFGGRDKGLEAFDQYLQTKTIWTVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYU0</accession>
    <name>A0A2S9GYU0_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 9">2-oxoisovalerate dehydrogenase subunit alpha</fullName>
            <ecNumber evidence="4 9">1.2.4.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7 9">Branched-chain alpha-keto acid dehydrogenase E1 component alpha chain</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">S2091_2306</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 9">The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 9">
            <text>(R)-N(6)-lipoyl-L-lysyl-[dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] + 3-methyl-2-oxobutanoate + H(+) = (R)-N(6)-(S(8)-2-methylpropanoyldihydrolipoyl)-L-lysyl-[dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] + CO2</text>
            <dbReference type="Rhea" id="RHEA:13457"/>
            <dbReference type="Rhea" id="RHEA-COMP:10488"/>
            <dbReference type="Rhea" id="RHEA-COMP:10489"/>
            <dbReference type="ChEBI" id="CHEBI:11851"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:83142"/>
            <dbReference type="EC" id="1.2.4.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the BCKDHA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.4.4" evidence="4 9"/>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92889">
        <property type="protein sequence ID" value="PRC92889"/>
        <property type="gene ID" value="S2091_2306"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003863">
        <property type="term" value="F:3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009083">
        <property type="term" value="P:branched-chain amino acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034616">
        <property type="entry name" value="BCKDH_E1-a"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001017">
        <property type="entry name" value="DH_E1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022593">
        <property type="entry name" value="Oxoisoval_DH_suAlpha_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43380:SF1">
        <property type="entry name" value="PTHR43380:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00676">
        <property type="entry name" value="E1_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12573">
        <property type="entry name" value="OxoDH_E1alpha_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0786">Thiamine pyrophosphate</keyword>
    <feature type="domain" description="OxoDH_E1alpha_N" evidence="12">
        <location>
            <begin position="6"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="domain" description="E1_dh" evidence="11">
        <location>
            <begin position="81"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="351"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00031050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00033712"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF12573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PRC92889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="410" mass="44978" checksum="5C67E10B77D5500F" modified="2018-07-18" version="1">MTQRNPLHLHVPEPTGRPGQVTDFSYLHLSPAGAIRRPPIDVLAVDTSDLTFALIRVLDEAGNAVGPWAPDLDPQTVRAGMRAMMKTRIFDARMLIAQRQKKMSFYMQSLGEEAIGTAHAMALQDGDMCFPTYRQQSLLLVRDVSMVDMICQLFSNERDPLKGRQLPVMYSVREAGFFSISGNLATQFIQAVGWGMASAIKGDTKIASAWIGDGATAEADFDTGLTFAHVYRAPVILNVVNNQWAISTFQAIAGGENTTFAARGVGCGIASLRVDGNDFLAVYAASKWAADRARSNLGPTLIEWVTYRAGPHSTSDDPSKYRPADDWACFPLGDPIERLKKHLIGIGAWSEQEHEATQKELEAEIIAAQKEAEQYGTLSNGYAPSAAAMFDDVYKDLPEHLRLQRQQLGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYW3</accession>
    <name>A0A2S9GYW3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2329</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92912">
        <property type="protein sequence ID" value="PRC92912"/>
        <property type="gene ID" value="S2091_2329"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="106" mass="11506" checksum="3B4D3A490138E598" modified="2018-07-18" version="1">MIPKLLDYLNYLDQDANACDAHEQAPVEAMSDFGLSHIEQQAMLSGDKAQVAQLLGMDPRDESPVIVISQFIDKDVQNISAHYANLLVADKALYQAKSGGRNSASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZ19</accession>
    <name>A0A2S9GZ19_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2396</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92979">
        <property type="protein sequence ID" value="PRC92979"/>
        <property type="gene ID" value="S2091_2396"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="212" mass="22982" checksum="6CF63E97C4BAC13B" modified="2018-07-18" version="1">MLEFNNANTLRISPTCVDDDIVGVACLNFSRSYLAIAVLTGFALTGCGGNQNDPPKENTLSQHVVSTSEIPALIRRVDQLSTALRKQPNTTSVGLHSVAGTYQGETSDGRLCSLMVDEDHPGFQFQVEREKIGIHWEPLAYAANGAVIHNLEDSSAPGQPGVQLTRFTNAPIPMTEVLILRIGTGTPALPQMIYLRTQGSTTKTVKCIFERK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZ43</accession>
    <name>A0A2S9GZ43_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Plasmid stabilization system protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2412</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92995">
        <property type="protein sequence ID" value="PRC92995"/>
        <property type="gene ID" value="S2091_2412"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2310.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007712">
        <property type="entry name" value="RelE/ParE_toxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035093">
        <property type="entry name" value="RelE/ParE_toxin_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05016">
        <property type="entry name" value="ParE_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-1277">Toxin-antitoxin system</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="104" mass="12041" checksum="A40502D772712B37" modified="2018-07-18" version="1">MKDYGYKVDLTEEALEQLIELFLFKCGQSDLLAAIEARDAIEEAIEQISRSPYIYPIADNDPTERKLVIPFVRKTGYIALFSIESESQIYLTNIRHQLQDDVLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZ64</accession>
    <name>A0A2S9GZ64_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2410</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92993">
        <property type="protein sequence ID" value="PRC92993"/>
        <property type="gene ID" value="S2091_2410"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="53" mass="6103" checksum="7E33C1142567F1F7" modified="2018-07-18" version="1">MKQTRLIELMVMVVAMLILSGCVWGGYGGYHEDEHHDRDRGEHRDGDHGDQNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZA1</accession>
    <name>A0A2S9GZA1_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Phosphate-specific transport system accessory protein PhoU</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_2114</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Plays a role in the regulation of phosphate uptake.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the PhoU family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93028">
        <property type="protein sequence ID" value="PRC93028"/>
        <property type="gene ID" value="S2091_2114"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030643">
        <property type="term" value="P:cellular phosphate ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045936">
        <property type="term" value="P:negative regulation of phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006817">
        <property type="term" value="P:phosphate ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.220">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028366">
        <property type="entry name" value="P_transport_PhoU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038078">
        <property type="entry name" value="PhoU-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026022">
        <property type="entry name" value="PhoU_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42930">
        <property type="entry name" value="PTHR42930"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01895">
        <property type="entry name" value="PhoU"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003107">
        <property type="entry name" value="PhoU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02135">
        <property type="entry name" value="phoU_full"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 3" id="KW-0592">Phosphate transport</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="PhoU" evidence="4">
        <location>
            <begin position="23"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="domain" description="PhoU" evidence="4">
        <location>
            <begin position="129"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR003107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC93028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="232" mass="25625" checksum="85924542306BD993" modified="2018-07-18" version="1">MTGEHSSRQYDTDLETLRSKVLLMGGLVENQFHDAIASFRVGNVELAASVIKADAGVNQLEVDLDDACRHLILKRQPAANDLRTVMATVKVITDLERIGDEASKIARIAQGKDTQRGALIFNDYEAVRGLASQVGNMLHDALDALARLDEKQAVKLIAKDAIIDQDFRAVMRNLITYMMEDPRTISAALDALWIAKAIERIGDHAKNIAEHVIFIVEGKDIRHTDYAATHLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZH6</accession>
    <name>A0A2S9GZH6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2194</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93108">
        <property type="protein sequence ID" value="PRC93108"/>
        <property type="gene ID" value="S2091_2194"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="268"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="271"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="489" mass="53473" checksum="666B767F48678FD0" modified="2018-07-18" version="1">MSSNKQIAVKDLVIDLANFRTVIQTNEQNAVHAMISISPAFFWGLMESLLDDGYLPTENIIVLERSDGTKVVKEGNRRIAALKIALKVIDTADLDLPPKIVKRIAGLSSNWIVDNTAVPCTVYGETDSAVVDKIITLTHGKGIKAGRDTWSAVARARHSRDMNGSIEAGLDLLEKFFIHSTNHTQEQRDRWAGDYSLTVLDEAIKKIASRLGSTSSLDLAKQYPKIEHKKALDDIIRAIGLETLGFSKIRGSEDFATLFGIPLPPSQDVSSVLGGDESNNMQDDGNSGASPDTNNVDVDSANTTTHPAESEGDDKSKDAQLVVKKPSNSKVIATPLEDEKSVKRALKSLKIMGQNRAKVATLRIEAGKLKLKDNPIAFCFLLRSMFEISAKAYCDDHSQSGLSVKKSDGSDKFLMDVLRDIINHLTQNKKDKTMLKMLHGPATELGRTDGILSITSLNQLVHHPTFAINSSQIPTTFAAVFPLLIEMNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZR9</accession>
    <name>A0A2S9GZR9_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">7-carboxy-7-deazaguanine synthase</fullName>
            <shortName evidence="5">CDG synthase</shortName>
            <ecNumber evidence="5">4.3.99.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Queuosine biosynthesis protein QueE</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">queE</name>
        <name evidence="6" type="ORF">S2091_2202</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>6-carboxy-5,6,7,8-tetrahydropterin + H(+) = 7-carboxy-7-deazaguanine + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:27974"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:61032"/>
            <dbReference type="ChEBI" id="CHEBI:61036"/>
            <dbReference type="EC" id="4.3.99.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </cofactor>
        <text evidence="5">Binds 1 S-adenosyl-L-methionine per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="5">Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Purine metabolism; 7-cyano-7-deazaguanine biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.3.99.3" evidence="5"/>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93116">
        <property type="protein sequence ID" value="PRC93116"/>
        <property type="gene ID" value="S2091_2202"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00391"/>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016840">
        <property type="term" value="F:carbon-nitrogen lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904047">
        <property type="term" value="F:S-adenosyl-L-methionine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008616">
        <property type="term" value="P:queuosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00917">
        <property type="entry name" value="QueE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024924">
        <property type="entry name" value="7-CO-7-deazaguanine_synth-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030977">
        <property type="entry name" value="QueE_Cx14CxxC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000370">
        <property type="entry name" value="QueE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00376">
        <property type="entry name" value="7-carboxy-7-deazaguanine_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04508">
        <property type="entry name" value="queE_Cx14CxxC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="3 5" id="KW-0408">Iron</keyword>
    <keyword evidence="4 5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0671">Queuosine biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="46"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="5">
        <location>
            <begin position="82"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="5">
        <location>
            <begin position="168"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="5">
        <location>
            <begin position="208"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="61"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="65"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="80"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="83"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="85"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="125"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="127"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="245"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC93116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="245" mass="27119" checksum="1624C49F0480FFF2" modified="2018-07-18" version="1">MKHKNAHASILVRSTGSFPLSAKLLFIRFFASSALTYSVKEIFYTLQGEGNHAGRPAVFCRFAGCNLWSGREVDRAKAICQFCDTDFVGTDGELGGKFKQAEELADVINGLWPAAYPANKYVVFTGGEPLMQLDAVLINAIHAAGFEIAIETNGTIAVPEGIDWVCVSPKMGAELIVFKGDELKVVIPQTGQDMQKYEQLDFKHFFVQAMDGPLQAENLRKAVNYCKLHPHWKLSLQTHKLLQIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H044</accession>
    <name>A0A2S9H044_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Primosomal protein N'</fullName>
            <ecNumber evidence="9">3.6.4.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">ATP-dependent helicase PriA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">priA</name>
        <name evidence="11" type="ORF">S2091_2092</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the primosome.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the helicase family. PriA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.-" evidence="9"/>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93354">
        <property type="protein sequence ID" value="PRC93354"/>
        <property type="gene ID" value="S2091_2092"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990077">
        <property type="term" value="C:primosome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006269">
        <property type="term" value="P:DNA replication, synthesis of RNA primer"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006268">
        <property type="term" value="P:DNA unwinding involved in DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1440.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00983">
        <property type="entry name" value="PriA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005259">
        <property type="entry name" value="PriA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041222">
        <property type="entry name" value="PriA_3primeBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042115">
        <property type="entry name" value="PriA_3primeBD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041236">
        <property type="entry name" value="PriA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040498">
        <property type="entry name" value="PriA_CRR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17764">
        <property type="entry name" value="PriA_3primeBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18074">
        <property type="entry name" value="PriA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18319">
        <property type="entry name" value="PriA_CRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00595">
        <property type="entry name" value="priA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 9" id="KW-0235">DNA replication</keyword>
    <keyword evidence="8 9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6 9" id="KW-0347">Helicase</keyword>
    <keyword evidence="5 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1 9" id="KW-0639">Primosome</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <keyword evidence="9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="10">
        <location>
            <begin position="148"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C4-type" evidence="9">
        <location>
            <begin position="377"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C4-type" evidence="9">
        <location>
            <begin position="404"/>
            <end position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC93354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="671" mass="74675" checksum="70352CED56C24422" modified="2018-07-18" version="1">MQSEKILQIVLDTPLERVFDYLWTGEETPQVGQFALLTFGRREMVGLIVAMKQNSDIPRDKLKSVLTVRQQLSPVSSEWIALCSFAADYYQRPLGEVALPAIPKNCRTSKTTALDKALKKLSLSLEVKGEPSESPQLNAAQQNAVQHIVDAKGYAPSLLYGVTGSGKTEVYLQAAAQVLARDASAQILILVPEINLTPQLQGHFQARFPELTVAVLHSGMAEGERTLHWLAAHTGKARLILGTRLAILASLPALKLIIIDEEHDPSYKQQEGLRYSARDLAIWRARQLNIPVVLGSATPSLETWQHTISGRYVKLSLPDRAVAAAVLPKMRLIDIAKDRPQEGLTASLISALKQRLDKGEQSLLYLNRRGYAPVIACDACGWMSNCTRCSAFLVLHKQEHKLRCHHCSFELRIPKSCPTCGNSDIQPLGRGTQRIEENLQKFFPDAKIRRIDADSTRLKGSAQAAFETVHRGEVDILIGTQMVAKGHDFKNLTLVGVINPDNALFSQDYRAGERLFAQLMQVSGRAGRAAQKEGGSVSEVLVQTRYPQHPLYHALKTHDYPRFAKECLAERQQAGLPPFIFQALLRAEAKELQIAIAFLRQAAELNVPEGIIMHDPIPMSLMKMANSERAQLLIESHSRPALQAFLKEWLLQLRTLKPRITWSLEVDPVDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H070</accession>
    <name>A0A2S9H070_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Peptidoglycan glycosyltransferase MrdB</fullName>
            <shortName evidence="6">PGT</shortName>
            <ecNumber evidence="6">2.4.1.129</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Cell elongation protein RodA</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Cell wall polymerase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Peptidoglycan polymerase</fullName>
            <shortName evidence="6">PG polymerase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">mrdB</name>
        <name evidence="6" type="synonym">rodA</name>
        <name evidence="7" type="ORF">S2091_2004</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Peptidoglycan polymerase that is essential for cell wall elongation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>[GlcNAc-(1-&gt;4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n)-di-trans,octa-cis-undecaprenyl diphosphate + beta-D-GlcNAc-(1-&gt;4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate = [GlcNAc-(1-&gt;4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n+1)-di-trans-octa-cis-undecaprenyl diphosphate + di-trans,octa-cis-undecaprenyl diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23708"/>
            <dbReference type="Rhea" id="RHEA-COMP:9602"/>
            <dbReference type="Rhea" id="RHEA-COMP:9603"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58405"/>
            <dbReference type="ChEBI" id="CHEBI:60033"/>
            <dbReference type="ChEBI" id="CHEBI:78435"/>
            <dbReference type="EC" id="2.4.1.129"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="6">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell inner membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the SEDS family. MrdB/RodA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.129" evidence="6"/>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93266">
        <property type="protein sequence ID" value="PRC93266"/>
        <property type="gene ID" value="S2091_2004"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008955">
        <property type="term" value="F:peptidoglycan glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02079">
        <property type="entry name" value="PGT_RodA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018365">
        <property type="entry name" value="Cell_cycle_FtsW-rel_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001182">
        <property type="entry name" value="FtsW/RodA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011923">
        <property type="entry name" value="RodA/MrdB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30474">
        <property type="entry name" value="PTHR30474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30474:SF1">
        <property type="entry name" value="PTHR30474:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01098">
        <property type="entry name" value="FTSW_RODA_SPOVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02210">
        <property type="entry name" value="rodA_shape"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00428">
        <property type="entry name" value="FTSW_RODA_SPOVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3 6" id="KW-0133">Cell shape</keyword>
    <keyword evidence="6" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="6" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="52"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="76"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="136"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="168"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="263"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="301"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="340"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC93266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="368" mass="40388" checksum="3306A1239D3003A1" modified="2018-07-18" version="1">MRRHHSPWQTIKPYVTVFDGPLAIIIFLIMSVGIVTLYSAGIDFPGRVQDQLRNILVAFIVMWIAANVPPQTLMRFAVPLYTVGVSLLIAVAIFGIVKKGSRRWINIGMVVQPSELMKIAMPLMLAWFFQKREGAVGWREFIVAALLLILPIAFIVKQPDLGTAMLVLAAGMAVIFLAGLSWRVIIGVIVLALASMPLVWHSMHDYQRERVLTLIDPTTDPLGKGFHIIQSTIAVGSGGITGKGWLKGTQAHLEFIPERTTDFIFAVFSEEFGLIGCCVLLVLYLLLFTRGLMIAANAPTFFTRLLAGSITTIFFTYAFVNMGMVSGILPVVGVPLPMMSYGGTALATLGWGAGILMSIQRHRKLIQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H082</accession>
    <name>A0A2S9H082_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2101</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93363">
        <property type="protein sequence ID" value="PRC93363"/>
        <property type="gene ID" value="S2091_2101"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="48"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="111" mass="12604" checksum="C52A5AF89F48C6E7" modified="2018-07-18" version="1">MNKLIPLDDAVAGMVLSTNLMGSHNEKLLPGGTVLTDSMISSLRRHQVEEVEVEIEEEFDAEAEAENAQNEKLKLEKKLARLDKLFKLTEHEKLNQQLKNYIIQFLTVGEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H089</accession>
    <name>A0A2S9H089_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="10">TonB dependent receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">S2091_1778</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93391">
        <property type="protein sequence ID" value="PRC93391"/>
        <property type="gene ID" value="S2091_1778"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039423">
        <property type="entry name" value="TonB-dep_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32552">
        <property type="entry name" value="PTHR32552"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="3 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0675">Receptor</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="2 5" id="KW-0798">TonB box</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015512809" evidence="7">
        <location>
            <begin position="30"/>
            <end position="814"/>
        </location>
    </feature>
    <feature type="domain" description="Plug" evidence="9">
        <location>
            <begin position="82"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="8">
        <location>
            <begin position="346"/>
            <end position="811"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="39"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC93391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="814" mass="86335" checksum="9A5B9BF57813B938" modified="2018-07-18" version="1">MANRQFNFICAAAVASTFASTFICAPTWAQEVAQTTAAPAASAPASTETPDSTATPAPTSVKNSNQIQTVIITANKRKEDASKVPLSISVIGGDELAAQHIEDFASATRSIPNISFSGGGGGGNAGNGPGLSNVEMRGISSEAGSATVGIYLDDVSMTVGNLYSMGSAEPKFFDLDHIEVLRGPQGTLYGASSMGGTVKFISNQPNLKIQETNISADVSSTAGGGTNNTETGVFNAVLIPNELALRIGVESAHKSGFINQVNPTTAAVIANGINWEDDRVARIAMKWMPTKDLSITPSVFYQQVNTGDIDVSYLTLLNGTPIPKNETAKLVREPGKDTMVVPSLTINYSMDVGDITSVTSYFKRNFNRTQDGTTVNSVYLGSQVQNDPALASVVGALPSAVFLNNEVTQFSQEVRIASKPYDQSVSPFTWVAGAYVSNMNTNITDNEPVYGINAAFNAAGMNPSNPADLAGTVTAGFPNDNSYFAHRAYHDTQQAVFGEANYYFIPTVHATAGLRFLEAKETFSRAAGLYFANDGTNDGNAYNVQDSSGSKATPKFAITWEVDKTDTLYATAAEGFRVGGSNFPLPMGYCGMTTPNPLSFGADTLWSYEVGDKSRFLDNTLSVNADLFYIDWKNLQQQITLANCGYAYNTNVGSATSYGGEIEVKYKPISSVVLDLAGGYTHATLSDDAGLNAGVVGAVKGADVPGVPKFNLALTGQYNFAINDDVMGFVRTAAHWTGTSNGTLAPSNPDYQRPAYANVDASTGVSFEKWDVSLYVRNIANSQKIIQRPQVQGTADEAYRMSPRTIGVTLTGKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0D5</accession>
    <name>A0A2S9H0D5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1797</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93410">
        <property type="protein sequence ID" value="PRC93410"/>
        <property type="gene ID" value="S2091_1797"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="14"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="333" mass="36426" checksum="333C0860AE82BE37" modified="2018-07-18" version="1">MSDTRVDRFVRSHLKTRHLVLLVELGRNGSILHAAQAANLTQPAASKLLSELEHALSVPLFDRLPRGVVPTCYGEVLIRRAGAALAEMDAAHQEIMELLSGLSGRVAIGTVMTPSISLLPQTVRLLKLRFPRVQVSICVDSSKTLVARLRKGELDMVIGRILDSESANELNFEPLSDEPHSLIVRADHPLAKTSDLHLEKLIEEGWIMPPAGSILRDRLTALFLARGLDQPGITVETTALPMITNLLIGSDMIAALPEELVRPYLDIGLLTVLPYDLGLRMDCYGIVTRRKYKLSPGAQAMLTILREVAANLQNQLKLDGMSTFSAAVEAGQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0L5</accession>
    <name>A0A2S9H0L5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">NDP-sugDHase: nucleotide sugar dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_1909</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93522">
        <property type="protein sequence ID" value="PRC93522"/>
        <property type="gene ID" value="S2091_1909"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016628">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000271">
        <property type="term" value="P:polysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017476">
        <property type="entry name" value="UDP-Glc/GDP-Man"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014027">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036220">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014026">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001732">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028359">
        <property type="entry name" value="UDP_ManNAc/GlcNAc_DH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00984">
        <property type="entry name" value="UDPG_MGDP_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03720">
        <property type="entry name" value="UDPG_MGDP_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03721">
        <property type="entry name" value="UDPG_MGDP_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF500136">
        <property type="entry name" value="UDP_ManNAc_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000124">
        <property type="entry name" value="UDPglc_GDPman_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00984">
        <property type="entry name" value="UDPG_MGDP_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52413">
        <property type="entry name" value="SSF52413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03026">
        <property type="entry name" value="NDP-sugDHase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0520">NAD</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UDPG_MGDP_dh_C" evidence="4">
        <location>
            <begin position="330"/>
            <end position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR000124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC93522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="443" mass="48942" checksum="DA3C77CAC3BF330E" modified="2018-07-18" version="1">MHLIYSFDLTAKVDIQMNTTVGVVGLGYVGLPLAVEFGKKIKTVGFDLSEKKVSNFHKFIDANGELSIEEMRAAEYLTTSTDPSTLSCADFIVIAVPTPVDFAHNPDFTPLRGASETVGRNMKRGAIVVYESTVYPGATEEICIPILERFSGMKWKQDFHVGFSPERINPGDKEHALPNIIKVVSGDDADTLDKIATLYETIIKAGVYRASNIKVAEAAKVIENTQRDLNIALMNELSIIFDMIGIDTLEVLQAAGTKWNFLNFRPGLVGGHCIGVDPYYLTHKADMLGYHPQVILAGRRINDGMAKFIAEKVVKEIIKANHHVKGCIVNVMGLTFKENCPDLRNSKVADMIYELQTYGVEVHVHDPIADAGEAQHEYGLKLDSWAELPKATVTIAAVSHHELLQRPLSDYQSKSLPNACFVDIKSQYDRSALTAAGFTIWRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0M1</accession>
    <name>A0A2S9H0M1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1890</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93503">
        <property type="protein sequence ID" value="PRC93503"/>
        <property type="gene ID" value="S2091_1890"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015615401" evidence="1">
        <location>
            <begin position="29"/>
            <end position="450"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="450" mass="50472" checksum="B0DCCBB5E903FC86" modified="2018-07-18" version="1">MKLFSFKPNLLVGVLCAVSCLICQNTIAAVNLNATIKTQNIKNKPDSKTPADTQESLDVTLDSGYMSMRSANEIKIFDFKTRRRFTLDDATKTYMDYSIYDTVGFRDLEFQNRENLNKRLAAAKIDVDTHRTIDNEHLFAVQSQTQRHVEEKDVGDDLEFSIEGRELARWSKAGVKVSAEDSSRFVNFLRYKLGGHPQILKRLAASGVIPNKIVLTFNEFWGTTTCTIVVNSAHQIDDVAYDLSAFSRRQAAKSSDKLDQILGQDRGITAAKLEHAKNGILTQQASDIRDGKLLDAMLAVFEFSLTTGQQIPPFTPDQLAKIRLDSSVQNLTHALGASTKEAMPDAITTLVNLRLNAPNKAYILKIFEANDRLKLGDSDAAKALFAEVLQTNPYIAGVYKDLGDLFYMRFDTAHAWQCWDIGRQIAPEFTNLKAVSQYEDLLTTQHSEYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0U7</accession>
    <name>A0A2S9H0U7_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Epoxyqueuosine reductase</fullName>
            <ecNumber evidence="7">1.17.99.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Queuosine biosynthesis protein QueG</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">queG</name>
        <name evidence="9" type="ORF">S2091_1588</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>AH2 + epoxyqueuosine(34) in tRNA = A + H2O + queuosine(34) in tRNA</text>
            <dbReference type="Rhea" id="RHEA:32159"/>
            <dbReference type="Rhea" id="RHEA-COMP:10345"/>
            <dbReference type="Rhea" id="RHEA-COMP:10346"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:82831"/>
            <dbReference type="ChEBI" id="CHEBI:82834"/>
            <dbReference type="EC" id="1.17.99.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="7">Binds 2 [4Fe-4S] clusters per monomer.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>cob(II)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:16304"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="7">tRNA modification; tRNA-queuosine biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the QueG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.17.99.6" evidence="7"/>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93587">
        <property type="protein sequence ID" value="PRC93587"/>
        <property type="gene ID" value="S2091_1588"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00392"/>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031419">
        <property type="term" value="F:cobalamin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052693">
        <property type="term" value="F:epoxyqueuosine reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008616">
        <property type="term" value="P:queuosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00916">
        <property type="entry name" value="QueG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004453">
        <property type="entry name" value="QueG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013542">
        <property type="entry name" value="QueG_DUF1730"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30002">
        <property type="entry name" value="PTHR30002"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08331">
        <property type="entry name" value="DUF1730"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00276">
        <property type="entry name" value="TIGR00276"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="7" id="KW-0846">Cobalamin</keyword>
    <keyword evidence="7" id="KW-0170">Cobalt</keyword>
    <keyword evidence="1 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 7" id="KW-0408">Iron</keyword>
    <keyword evidence="6 7" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4 7" id="KW-0671">Queuosine biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="8">
        <location>
            <begin position="186"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Cob(II)alamin binding" evidence="7">
        <location>
            <begin position="251"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="7">
        <location>
            <position position="144"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="61"/>
        </location>
        <ligand>
            <name>cob(II)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:16304"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="144"/>
        </location>
        <ligand>
            <name>cob(II)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:16304"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="168"/>
        </location>
        <ligand>
            <name>cob(II)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:16304"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="179"/>
        </location>
        <ligand>
            <name>cob(II)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:16304"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="198"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="201"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="204"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="208"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="224"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="226"/>
        </location>
        <ligand>
            <name>cob(II)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:16304"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="233"/>
        </location>
        <ligand>
            <name>tRNA</name>
            <dbReference type="ChEBI" id="CHEBI:17843"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="251"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="254"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="258"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC93587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="366" mass="40884" checksum="BAC021CAF38FEE3C" modified="2018-07-18" version="1">MINDNYPFLALSIKAWGQELGFSDVRISDVDLSQHEAGLSAWLAAGYHGEMEYMAAHGMKRARPAELVPGALRAIMVRMDYLPPESPPNWRNVEHQRAQQAGQAIISLYARGRDYHKVLRGRLQELANRIEVEVGEFGYRVFTDSAPVMEVALAEKAGLGWRGKHTLLLNRQAGSLFFIGEIITDLPLPVDPPVTPHCGQCTACITSCPTQAILAPYKLDARRCISYLTIELKTSIPIELRPLIGNRVYGCDDCQLCCPWNKFAQVSEQADFAVRNGLDNASLIDLFSWSEADFMKKLEGSPIRRIGYISWLRNLAVGLGNAKRELSMHQMDTSELDSALQKQISHPSEIVREHVLWALQQTAIVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0V7</accession>
    <name>A0A2S9H0V7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Amidohydrolases: amidohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1883</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93496">
        <property type="protein sequence ID" value="PRC93496"/>
        <property type="gene ID" value="S2091_1883"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017439">
        <property type="entry name" value="Amidohydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11014">
        <property type="entry name" value="PTHR11014"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005962">
        <property type="entry name" value="Pept_M20D_amidohydro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="SSF55031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01891">
        <property type="entry name" value="amidohydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="M20_dimer" evidence="2">
        <location>
            <begin position="236"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="459" mass="48821" checksum="5D409DEABC2A8AE6" modified="2018-07-18" version="1">MHHLKSGINLAVAIVLTITLSTSYGDDDKAFSPLNQIMDHQLNSDIAELVNTYKDIHSHPELSHHEQRTSEILASELRKAGYKVTERVGKYPDGSQAFGVVAILENGPGPRLLLRADMDALPIIEETGVSYASHVKSTNAAGQEVGVMHACGHDVHVTTMIGTARALAANRSSWHGTLMLIGQPSEETLDGAKAMLADHLYERFGTPDMVIMLHDTNTLAAGTVSVSSGNTAAAVTSIDVTMRGVGGHGARPHATIDPVVMAGEFIVQLQTIVSRQQDPLDPAVVTIGDIRGGTKRNIIPDEVKMELTTRAYSDKAMKIIIDGVKRTAQGVALSAGVPEDRQPIVTVLKEESGPALFNDPALSNRVKSELAIALGASNVSVEPPIMGSEDFGNFGLPDRQIPVVMFRLGAMDPAKFAAAQKAGKPLPGPHTSHFEPTPELTLRTGVTAMTSVAVSLLQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H162</accession>
    <name>A0A2S9H162_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Microcystinase C</fullName>
            <shortName evidence="1">MlrC</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_1720</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in peptidolytic degradation of cyclic heptapeptide hepatotoxin microcystin (MC).</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="1">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M81 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93719">
        <property type="protein sequence ID" value="PRC93719"/>
        <property type="gene ID" value="S2091_1720"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009197">
        <property type="entry name" value="MlrC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010799">
        <property type="entry name" value="MlrC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015995">
        <property type="entry name" value="MlrC_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07364">
        <property type="entry name" value="DUF1485"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07171">
        <property type="entry name" value="MlrC_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF012702">
        <property type="entry name" value="UCP012702"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF1485" evidence="3">
        <location>
            <begin position="2"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="domain" description="MlrC_C" evidence="2">
        <location>
            <begin position="299"/>
            <end position="480"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR012702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC93719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="491" mass="53920" checksum="17A6E2E657819EE2" modified="2018-07-18" version="1">MRLLLAMFKHETNTFSPVPTKFERFFPGYPNALSGTKAINELRDTGCSLAGFIKVAEQHGAEIEVAVAATAWPSGPVDNEAYERISALILEQVKQGGFDGILLDLHGAMVSHSCEDGEGRLLQRLREIDSTTPVGVTLDMHANMYDELIKNATVVNGYHTYPHIDMFEAGVRTADIIIRTIKGEIKPVMAWGMKPMLPHVLMQGTHMEPNKSLQEQCIAMEQSKVLASSLFVGFPQADIANAGLSVVICTNDDAQLARQKCDTLLDDAWKVREQFLYHSEPLIDSIVRAKLCIEYPVVLLDHCDNCASGGTLDSTVVLAEIIRQDLNNVVFYAIKDPLAARQAAHSGVGTKLTLLLGGKTPMPALRDSSHPISVEATVKTISDGIFYNRGPMLQGMMNNTGLTVVVDTGRVVIVIISEDIEPHDINCLLSLGIDPLKKSYIALKSRVHWRAGFGEMARHVIECAGLGVTTSDYSQLVYRHVRRPIYPLDAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H165</accession>
    <name>A0A2S9H165_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">tRNA N6-adenosine threonylcarbamoyltransferase</fullName>
            <ecNumber evidence="6">2.3.1.234</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">N6-L-threonylcarbamoyladenine synthase</fullName>
            <shortName evidence="6">t(6)A synthase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">tRNA threonylcarbamoyladenosine biosynthesis protein TsaD</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">tsaD</name>
        <name evidence="8" type="ORF">S2091_1607</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>adenosine(37) in tRNA + L-threonylcarbamoyladenylate = AMP + H(+) + N(6)-L-threonylcarbamoyladenosine(37) in tRNA</text>
            <dbReference type="Rhea" id="RHEA:37059"/>
            <dbReference type="Rhea" id="RHEA-COMP:10162"/>
            <dbReference type="Rhea" id="RHEA-COMP:10163"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:73682"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74418"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.3.1.234"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="6">Binds 1 Fe(2+) ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the KAE1 / TsaD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.234" evidence="6"/>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93606">
        <property type="protein sequence ID" value="PRC93606"/>
        <property type="gene ID" value="S2091_1607"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061711">
        <property type="term" value="F:N(6)-L-threonylcarbamoyladenine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002949">
        <property type="term" value="P:tRNA threonylcarbamoyladenosine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01445">
        <property type="entry name" value="TsaD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000905">
        <property type="entry name" value="Gcp-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017861">
        <property type="entry name" value="KAE1/TsaD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017860">
        <property type="entry name" value="Peptidase_M22_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022450">
        <property type="entry name" value="TsaD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11735">
        <property type="entry name" value="PTHR11735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11735:SF6">
        <property type="entry name" value="PTHR11735:SF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00814">
        <property type="entry name" value="TsaD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00789">
        <property type="entry name" value="OSIALOPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00329">
        <property type="entry name" value="gcp_kae1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03723">
        <property type="entry name" value="T6A_TsaD_YgjD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01016">
        <property type="entry name" value="GLYCOPROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="4 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 6" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="TsaD" evidence="7">
        <location>
            <begin position="24"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="6">
        <location>
            <begin position="134"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="111"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="115"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="167"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="180"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="274"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="302"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC93606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="340" mass="36141" checksum="7E25987CF6F94FAF" modified="2018-07-18" version="1">MIVLGVESSCDETGLALVDTETGLLSHALYSQITMHQEYGGVVPELASRDHIRRALPLLEQVLREANLDKSAIDAIAYTQGPGLAGALLVGASVACGLGLALGRPMLGIHHLEGHLLSPLLSSKPPQFPFISLLVSGGHTQLMRVEGVGKYTLLGETLDDAAGEAFDKSAKLLGLSYPGGPAISRLAESGDPSVYNLPRPMLHSKDLNFSFSGLKTAVLTVVKNHVGELTEQDKANVARGFVDALVDVIVAKCSTAMRHSALKRLVIAGGVGANTQLRAGLNAAAAKKRFEVYYPELEFCTDNGAMIAFAGAMRLKADPSQAQFDYAFNVRPKWPLDQLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1F5</accession>
    <name>A0A2S9H1F5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1389</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93780">
        <property type="protein sequence ID" value="PRC93780"/>
        <property type="gene ID" value="S2091_1389"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="66" mass="7346" checksum="094E5560B4C49B9F" modified="2018-07-18" version="1">MTHLTKDRSNWCPQHHSALRLNAAMLLIPTSGHHTGGHTMRSLSQKVQAVDNRLCAELVKDGMNND</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1G5</accession>
    <name>A0A2S9H1G5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">P pilus assembly protein pilin FimA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1392</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93783">
        <property type="protein sequence ID" value="PRC93783"/>
        <property type="gene ID" value="S2091_1392"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009289">
        <property type="term" value="C:pilus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007155">
        <property type="term" value="P:cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1090">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000259">
        <property type="entry name" value="Adhesion_dom_fimbrial"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036937">
        <property type="entry name" value="Adhesion_dom_fimbrial_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008966">
        <property type="entry name" value="Adhesion_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00419">
        <property type="entry name" value="Fimbrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49401">
        <property type="entry name" value="SSF49401"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015473939" evidence="1">
        <location>
            <begin position="20"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="domain" description="Fimbrial" evidence="2">
        <location>
            <begin position="25"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="177" mass="17790" checksum="46C8F267E0452B08" modified="2018-07-18" version="1">MNLKYTAFLLAIAPAFAFAQGANTITFQGEINASTCSVAINGVSANPTVLIPTISTAALNEKGKFGPTTTFAIGVTGCTAPTTADQAINTTFVGNNVTSGGNLLNTGKAKGVSLQLLDGTGTTGYNLTGGYTATGLVLPKGETTATHNFGVRYIAEGTDAVAPGSVIGSVQYSVAYP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1I5</accession>
    <name>A0A2S9H1I5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative addiction module killer protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1412</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93803">
        <property type="protein sequence ID" value="PRC93803"/>
        <property type="gene ID" value="S2091_1412"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014056">
        <property type="entry name" value="Addiction_killer_pred"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009241">
        <property type="entry name" value="HigB-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41791">
        <property type="entry name" value="PTHR41791"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05973">
        <property type="entry name" value="Gp49"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028744">
        <property type="entry name" value="Addict_mod_HI1419"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02683">
        <property type="entry name" value="upstrm_HI1419"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="97" mass="10823" checksum="3BD03E1010A6ECB2" modified="2018-07-18" version="1">MFSIKPLPEFTNWLNDLSDTTVRGVVVARIKRLERGLMGDVESVGDGVSELRIHIGAGWRVYFTQRGTQIIVLLVGGSKRTQKRDIKRAKSLAALLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1Q6</accession>
    <name>A0A2S9H1Q6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Tetratricopeptide repeat</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1534</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93925">
        <property type="protein sequence ID" value="PRC93925"/>
        <property type="gene ID" value="S2091_1534"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="388" mass="42909" checksum="BB34B8911103D71B" modified="2018-07-18" version="1">MNSTPNTANPSSALTRMLGYLEQDPQNEPLTFDTIDLCLAENNLDLTDRLLLNAAKNWPEALGVLNRKAIVALRRNTPHVAIIELEKIMASGKADAAIRYNLAYANYLIGNYARTCEVIKPALDDADRIPGLDSIYVLSLHQRGEIDTAIAYAEKRLKTKPTDTELQGVLALLYLDAEKDIDTCRQYTYAALRSNPNHPMALVTASALSMMDEKPAAAVEFAQKIISRNPSDGRAWSSIGVAQMYLLDLPAAQTALKNAVQHMSNHIGTWHGLAWTQLLQNDIDGAEASYNQAIELDRTFGESQAGLAIIAQLRGDKIKAKRLMDRAKRLAPSAMTLHYLKLLQLEESGDHSTAQSYLQDVLKRTPSFMGDSVLDMVRRMGRSNIKTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1Y8</accession>
    <name>A0A2S9H1Y8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Cytochrome c1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_1162</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC93989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93989">
        <property type="protein sequence ID" value="PRC93989"/>
        <property type="gene ID" value="S2091_1162"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002326">
        <property type="entry name" value="Cyt_c1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10266">
        <property type="entry name" value="PTHR10266"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02167">
        <property type="entry name" value="Cytochrom_C1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 6" id="KW-0349">Heme</keyword>
    <keyword evidence="5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015573195" evidence="7">
        <location>
            <begin position="21"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="8">
        <location>
            <begin position="37"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC93989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="253" mass="28565" checksum="6A19868BCA111F04" modified="2018-07-18" version="1">MKFVKTFIATLVLLPALALASEGYPLDKAPDRANNMAALQNGAKLFVNYCLNCHSAVSMRYSRLKDLGLTDDQIKNNLLLAGDKVGDLMTTHLSVKDAKAWFGAAPPDLSVIARSKSSEAGSGPDWLYTYLRTYYKDESRPTGWNNMVFPNVGMPHVLWELQGVRSAEFEEVEDEHDHAKKTIEFKKFTMLTPGKLTPLEYDNEVADLVGYLNWMGEPAQSTRKRLGVWVLMWLSLLSLLAWRLNASYWKEVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H240</accession>
    <name>A0A2S9H240_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Putative mRNA interferase YoeB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_1201</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the YoeB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94028">
        <property type="protein sequence ID" value="PRC94028"/>
        <property type="gene ID" value="S2091_1201"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006401">
        <property type="term" value="P:RNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2310.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035093">
        <property type="entry name" value="RelE/ParE_toxin_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009614">
        <property type="entry name" value="YoeB_toxin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38039">
        <property type="entry name" value="PTHR38039"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06769">
        <property type="entry name" value="YoeB_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143011">
        <property type="entry name" value="SSF143011"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02116">
        <property type="entry name" value="toxin_Txe_YoeB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00030388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC94028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="88" mass="10414" checksum="1FCD324A575D256A" modified="2018-07-18" version="1">MKRHLCFTPTAWDDYSYWQSQDRKMLKRINVLINGMLRDPFEGIGKPESLLGNLSGFWSRRIDDVHRLVYAVEDSQIIIIACRGHYDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H243</accession>
    <name>A0A2S9H243_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1227</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94054">
        <property type="protein sequence ID" value="PRC94054"/>
        <property type="gene ID" value="S2091_1227"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="46" mass="4920" checksum="2F8ED1A7CF46DB20" modified="2018-07-18" version="1">MIDHIGIRTANADKLILFYTNVLATLGIEKKAENPGGACFVTTAKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H283</accession>
    <name>A0A2S9H283_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1243</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94070">
        <property type="protein sequence ID" value="PRC94070"/>
        <property type="gene ID" value="S2091_1243"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015035">
        <property type="term" value="F:protein-disulfide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007263">
        <property type="entry name" value="DCC1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04134">
        <property type="entry name" value="DCC1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="136" mass="15601" checksum="FA013F087D70C70B" modified="2018-07-18" version="1">MKNTNPMTEDVWLVYDGECPVCKTYCKYIRIRDAVGKLHLVDARNSGELMDEITRAGLDIDQGMVLKFKGAIYYGPDAIHMLTLLSSPSGIFNRINYYVFRTNFGAKFFYPICKAFRTALLKLLGIKYIENLKQAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2B5</accession>
    <name>A0A2S9H2B5_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="9 10">Protein translocase subunit SecY</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">secY</name>
        <name evidence="13" type="ORF">S2091_1295</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9 10">The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 11">Membrane</location>
            <topology evidence="1 11">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9 12">Belongs to the SecY/SEC61-alpha family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94122">
        <property type="protein sequence ID" value="PRC94122"/>
        <property type="gene ID" value="S2091_1295"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0065002">
        <property type="term" value="P:intracellular protein transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006605">
        <property type="term" value="P:protein targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043952">
        <property type="term" value="P:protein transport by the Sec complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3370.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01465">
        <property type="entry name" value="SecY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026593">
        <property type="entry name" value="SecY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002208">
        <property type="entry name" value="SecY/SEC61-alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030659">
        <property type="entry name" value="SecY_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023201">
        <property type="entry name" value="SecY_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10906">
        <property type="entry name" value="PTHR10906"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00344">
        <property type="entry name" value="SecY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004557">
        <property type="entry name" value="SecY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103491">
        <property type="entry name" value="SSF103491"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00967">
        <property type="entry name" value="3a0501s007"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00755">
        <property type="entry name" value="SECY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00756">
        <property type="entry name" value="SECY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9 11" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9 11" id="KW-0811">Translocation</keyword>
    <keyword evidence="4 9 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9 11" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="116"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="148"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="180"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="212"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="268"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="316"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="371"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="397"/>
            <end position="416"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000537"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU004349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PRC94122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="443" mass="48079" checksum="8FF4C80008D3DCE6" modified="2018-07-18" version="1">MATTPQLAKGAASGFPWGRLWFLLSALVVYRIGTHIPVPGIDPAQLTQLFNQNSGGILGMFNMFSGGALSRFSVLALGIMPYISASIIMQLMSIVSPQLEALKKEGESGRRKITQYTRYGTLFLAAFQAFGIAVALEHQANLVIDPGMAFRLTTAVTLVTGTMFLMWLGEQITERGLGNGISIIIFAGIASGLPNAVAGLFELVRTGSMNPFSAMLICLIAAGVTYLVVFIERGQRKILVNYAKRQVGNKIYGGQSSHLPLKLNMAGVIPPIFASSIILFPATITGWFVSTGDNSPFMRFLKDLALSMGPGEPIHALLYAVAIVFFCFFYTALVFNSKETADNLKKSGAFVPGIRPGDQTARYIDKILMRLTLAGAVYITLVCLLPEFLVAKWKVPFSFGGTSLLIIVVVTMDFMAQVQNYVMSQQYDSLLRKANFKGGISSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2G3</accession>
    <name>A0A2S9H2G3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">GGDEF: diguanylate cyclase (GGDEF) domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_1342</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94169">
        <property type="protein sequence ID" value="PRC94169"/>
        <property type="gene ID" value="S2091_1342"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="46"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="2">
        <location>
            <begin position="69"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="3">
        <location>
            <begin position="149"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC94169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="282" mass="31745" checksum="840625A135EF20A4" modified="2018-07-18" version="1">MNNSSLRIQLHITIIFLILFVSSAIVGIMVLAIPRADFIGGISRNLFQSIALVVVFIILTLIIGLSVIEHMLRDIRHITQVAKKMGQGEPLPRPHNYRKDEIGHLVKTFIEMENKLRFDCLTHIYNRDFLIAQIEFLERHAAQHPSKKVSFTLLFLDLDKFKTINDSYGHAAGDQLLIVIAARLKAAVRETDTVARFGGDEFVVLLNGASNNIDIETTVDKIHALVEQPIALSNTIVSVRVSIGWATFPLDASNYPKLVEIADKRMFSSKKSRNDVHLRLVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2K7</accession>
    <name>A0A2S9H2K7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0835</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94214">
        <property type="protein sequence ID" value="PRC94214"/>
        <property type="gene ID" value="S2091_0835"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="305" mass="35096" checksum="1976B2D6FCD54AE1" modified="2018-07-18" version="1">MKMINKDFIVSEQDIASFQDRGFLLLKKFFNEDMIAYLQRRTSEQIAAPTDKYQSGFNRLAFDMFEGDQQIDDLLQDPTYRKTVLALTKRNLLFTQSIGFELKKNTSAGFPWHIGTQSFGYHRAEDFGCTIWTPLAPIDTSKQRSGMAYTPKNIISGEFMYNNVDPAVFDCLEKRANSGQKVEMAEFMELRDGPLNAVAMKTLLDYFCVEDDFELGDALIFDKYVIHRSVMLEVGPLELRAAFVMRFVCETSQYDYKRAHSLEIPRKYFGYAGPTKFHLEVCESDGDLIKNSPLFPDREKRLIAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2P7</accession>
    <name>A0A2S9H2P7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Peroxiredoxin, Ohr subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0872</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the OsmC/Ohr family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94251">
        <property type="protein sequence ID" value="PRC94251"/>
        <property type="gene ID" value="S2091_0872"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019953">
        <property type="entry name" value="OHR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003718">
        <property type="entry name" value="OsmC/Ohr_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036102">
        <property type="entry name" value="OsmC/Ohrsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33797">
        <property type="entry name" value="PTHR33797"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02566">
        <property type="entry name" value="OsmC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82784">
        <property type="entry name" value="SSF82784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03561">
        <property type="entry name" value="organ_hyd_perox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="141" mass="14487" checksum="523C3EF22658FF68" modified="2018-07-18" version="1">MKIATILYRAYAKATGGRDGRAVSSDAVLDIKLVTPKELGGAGGAGTNPEQLFAAGYSACFLGAMKFVAARDKIAIPPDVAVDGSVGIGAIATGFGIEVELRISLPGLDRAVAEDLIAKAHIVCPYSNATRNNIDVTLVLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2X7</accession>
    <name>A0A2S9H2X7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Growth inhibitor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0941</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94320">
        <property type="protein sequence ID" value="PRC94320"/>
        <property type="gene ID" value="S2091_0941"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003477">
        <property type="entry name" value="PemK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011067">
        <property type="entry name" value="Plasmid_toxin/cell-grow_inhib"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33988">
        <property type="entry name" value="PTHR33988"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02452">
        <property type="entry name" value="PemK_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="120" mass="13739" checksum="256D567A3F54015A" modified="2018-07-18" version="1">MVSKIWIPERRDIIWIDFNPQVGQETKDMHPLLVLSPKEFNDRTRIVIGLPMTTAKSNETNPFAVKFVGEKGKVSYVLAHQPKSFDWRLKGGKPHPWKQASEEVLIQAGEMLNQIIAICE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3B0</accession>
    <name>A0A2S9H3B0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1082</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94461">
        <property type="protein sequence ID" value="PRC94461"/>
        <property type="gene ID" value="S2091_1082"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="73" mass="8188" checksum="BE7B1AB496D77F02" modified="2018-07-18" version="1">MAKKKTEEIDAETMAVIEWCIEVEGHLVAAGATQAQAQDHIEEHVEWFTDLFYDGLTPEQAAKEALNDPEENT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3J8</accession>
    <name>A0A2S9H3J8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ABC-type transport system involved in resistance to organic solvents permease component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0562</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94559">
        <property type="protein sequence ID" value="PRC94559"/>
        <property type="gene ID" value="S2091_0562"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030802">
        <property type="entry name" value="Permease_MalE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30188">
        <property type="entry name" value="PTHR30188"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02405">
        <property type="entry name" value="MlaE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="122"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="164"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="196"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="278"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="309"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="352"/>
            <end position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="373" mass="40594" checksum="5839F47441FEEF9A" modified="2018-07-18" version="1">MIKPETPQLIESASATIAVTGCWQVHAFMEGQLMKKLTASLTKLGHQTQLKWDLSQVSALDHIGAQMLWNCWGKTRPAQLILLPTQEAFFSRLELANQLKIPKPPKSRLTSVMQLGTLMLDFISHLFAFIVLLGQLVLDLLTVLRRPNRAPWKEISANIFHMGFRALGITALVGILIGVVLSYLSAQQLRTFGGDIYLVNILGMSIIRELGPMLAAILVAGRSGSSITAQLGVMRVTEELDAMLVMGIPHGLRLIFPKVIALAIAMPLIVIWTDAMALIGGMLSANFILGMSPRFFIQKLPEVVPISNYYIGLGKGVAFGAAIALVACHFGLRIKPNTESLGQGTTTSVVSAITMVIILDAVFAIIFSRVGYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3K0</accession>
    <name>A0A2S9H3K0_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Putrescine-binding periplasmic protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0565</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Required for the activity of the bacterial periplasmic transport system of putrescine.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial solute-binding protein PotD/PotF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94562">
        <property type="protein sequence ID" value="PRC94562"/>
        <property type="gene ID" value="S2091_0565"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019808">
        <property type="term" value="F:polyamine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015846">
        <property type="term" value="P:polyamine transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006059">
        <property type="entry name" value="SBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001188">
        <property type="entry name" value="Sperm_putr-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13416">
        <property type="entry name" value="SBP_bac_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF019574">
        <property type="entry name" value="Periplasmic_polyamine_BP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00909">
        <property type="entry name" value="SPERMDNBNDNG"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0574">Periplasm</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR019574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="391" mass="43271" checksum="789ED171DF6CE741" modified="2018-07-18" version="1">MKIEKLSRCLCVKPVQRIKQRASQTLCAMLGLSFISVALLGSTSALAQEEKVLNIYNWSDYIADDTIKNFEKETGIKVRYDVFDTNEILHAKLVARKTGYDIVVPSDTFAQLQIQGGLLKTLDKSKLPNLVNMDPVVQTALAKLDPNNDHLVTWLWGYTTVGINTKKVKAALGDMPMPVNAWDLIFDPKYASKLSSCGISFMDSGNEVLPAALLYVKKNAHSQVASDYQEAGRMLATVRPYVRVFSSSSYINDLANGALCVAMGYSGDINIARQRAIQSKNGNEIQALVPSTSAVLFFDAMAIPVDAPHPNNALIWMNYIMRPEVHASLTNKVFYANPNSASLKFVKKDVVDNKTVFLSEEDKKRMTAPEPVSAAIRKIMSRTFTQFKTGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3Q4</accession>
    <name>A0A2S9H3Q4_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Spermidine/putrescine import ATP-binding protein PotA</fullName>
            <ecNumber evidence="8">7.6.2.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">potA</name>
        <name evidence="10" type="ORF">S2091_0566</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.6.2.11" evidence="8"/>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94563">
        <property type="protein sequence ID" value="PRC94563"/>
        <property type="gene ID" value="S2091_0566"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015417">
        <property type="term" value="F:ABC-type polyamine transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008995">
        <property type="entry name" value="Mo/tungstate-bd_C_term_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005893">
        <property type="entry name" value="Sp_pt_ABC_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013611">
        <property type="entry name" value="Transp-assoc_OB_typ2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08402">
        <property type="entry name" value="TOBE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50331">
        <property type="entry name" value="SSF50331"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01187">
        <property type="entry name" value="potA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 7 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-1278">Translocase</keyword>
    <keyword evidence="1 8" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="9">
        <location>
            <begin position="25"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="57"/>
            <end position="64"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU364083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC94563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="380" mass="41671" checksum="FC8BE23AAC0409A9" modified="2018-07-18" version="1">MASGDTLKSSFGVAAESNGMGKPFLFINNLIKDFGDNRVVNNVSLTINKGDIFALLGSSGCGKSTLLRMLAGFETPTSGEIILDGKNIVGDAPYHRPINMMFQSYALFPHLTVWDNIAFGLRREGMAKEEIADRVEKMLALVQLESFGKRKPYQLSGGQQQRVALARSLAKRPQLLLLDEPLAALDKKLRERTQLELVNIIEQVGVTCVMVTHDQEEAMAMACRIAVMSEGVILQTGEPNHVYETPNCRFVADFIGSVNMFTGELEVDEPDHVVISTPECKHYVGHGITGTLGMSVSVAVRPEKISVSVEAPDQQYNCVHGEVVELAYLGSYTVYHIKLASGMTIKASVSNSVRHGAFHPKWGDKLFAYWTDDAMVVLTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3R7</accession>
    <name>A0A2S9H3R7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CAAX protease self-immunity</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0576</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94573">
        <property type="protein sequence ID" value="PRC94573"/>
        <property type="gene ID" value="S2091_0576"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071586">
        <property type="term" value="P:CAAX-box protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003675">
        <property type="entry name" value="Rce1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02517">
        <property type="entry name" value="Rce1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="67"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="102"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="154"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="175" mass="19285" checksum="FB91782120ABB4D9" modified="2018-07-18" version="1">MNAATNIFNMKMDALMPERPFLSAIFFGLWLSLVTLSVSLIFAAIAEYFPGLSIDSSYTSGLEKLNYIDLFVICVLVGPLLETLVLQLFLIEVVRKFTASKYSAIVLSAAAFGLGHYYHGGLSKSIPTFMTGLIFAYGYSQVRTKGIFTSYTVTGVAHVMHNFIALFVLAPIFDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H410</accession>
    <name>A0A2S9H410_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_0609</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94606">
        <property type="protein sequence ID" value="PRC94606"/>
        <property type="gene ID" value="S2091_0609"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Histidine kinase" evidence="4">
        <location>
            <begin position="438"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="358"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC94606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="670" mass="75246" checksum="06F0F352DCA25B06" modified="2018-07-18" version="1">MTENLASNELSPLATAEILLKIDNIISEAEPKRSIDPATALELTGQAILLARLHALELSPELARALFLRCKILTEFSNYGEALKAGTEALNIAELHHDVRLVKSLLLSIANTYGYQGIYDEALNYMHRAINLHDAQSTEDEDLIWLGRSLNNMGYNYVMMGKSETGLPHLHRSLDILRKTDDKELLSRVLDSLSNAYLNLNDLATALPLALEAHQIAIENKHLSVMAISSAHAAKIYIKMHEIKLAEPFLHQALKLSTTNRFLLIKAQVLHLYAELEKQRHAPQASVTYLQKALVIAKKIDGNHHVADLLGELADHYKQHGEFAQALHYTEQQHEVREHYFSQQSGWRLKSLEIAQEVAQIKRENELIRQKNSALQNEIKNKQLTHYSEQLEAEVKLRTTELEKTNQHLKSALLNIEHNQLELAHAERMAAMGSMVVGVAHELNTPIGNCVLVASTLEDQTHQFLGLMHSDMMRRSDLANYLDKSEHSIRLLTKSLNNAVRLVNNFKQIAITRENQDRRSFFLHQLIKEIGDACNDHFLENPFEIEWEIPNDLTLVSYPNSVVQIFVLLIENAGLHAFEGRTNGVLNIAARLKEEDVLIEVNDNGVGMSAEVMTHIFDPFFTTKLGKGGNGLGLSIIFNLVKNILGGEIHVSSKVGLGSCFSISIPRVSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H421</accession>
    <name>A0A2S9H421_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0737</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94734">
        <property type="protein sequence ID" value="PRC94734"/>
        <property type="gene ID" value="S2091_0737"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="41" mass="4702" checksum="B924E80EDB6A5687" modified="2018-07-18" version="1">MNEDKKAARRVAIEHAKANNFPSGFESTKYGLSIYEQSERK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H453</accession>
    <name>A0A2S9H453_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HDOD domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0765</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94762">
        <property type="protein sequence ID" value="PRC94762"/>
        <property type="gene ID" value="S2091_0765"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013976">
        <property type="entry name" value="HDOD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08668">
        <property type="entry name" value="HDOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51833">
        <property type="entry name" value="HDOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HDOD" evidence="1">
        <location>
            <begin position="31"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="526" mass="58106" checksum="1ABACE6D160A012D" modified="2018-07-18" version="1">MNKNTVPVLNDQQVRQRRDQLLFQISTDQRLPSLGIAISTVIKIASTGEESVNKLANFILADVGLTKDILNLANSVSYRKSQGTSVTTISKAIFILGFDVVKTSALGMLMLECFNEQDQSLYYELTHSLCSSIIARECVSRSMYQDAEEASISALFKNMGQVLISAQAPDLYREIMQPVKDGTDTLHHSAVQHLGCSLAHFGSMVLQQWNMPDSIVQAIGALPFGEIKKSRHRSEWVKQVAAFSSDAAEVVMRNTQFMPGSTKEINFENEKYTKELMQRYGAALELDPKILPSWLDRAVKETEQLVLKLGMRTVTANASTKGGAATNTETVLPDDLLMSSATEVEDKPNYPSGKPHNARDLLLAGVMEMTQTISTGKFQLNDLVLQLLEILHGSLGFQFVTASLKDVKSERYVARISLGQDWHNKQKNFNFSSKGAGDLFHLALKNNADLMIGDTSSTKIHDLRPEWHLTHFPDVKSLMILPLIVNGKAIGLIYADRNCVAPEGVPPDETSLVKTMKGQLLAAMSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4A9</accession>
    <name>A0A2S9H4A9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Methyl-accepting chemotaxis protein (MCP) signaling domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">S2091_0801</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94798">
        <property type="protein sequence ID" value="PRC94798"/>
        <property type="gene ID" value="S2091_0801"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004888">
        <property type="term" value="F:transmembrane signaling receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004090">
        <property type="entry name" value="Chemotax_Me-accpt_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004089">
        <property type="entry name" value="MCPsignal_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033480">
        <property type="entry name" value="sCache_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00015">
        <property type="entry name" value="MCPsignal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17200">
        <property type="entry name" value="sCache_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00260">
        <property type="entry name" value="CHEMTRNSDUCR"/>
    </dbReference>
    <dbReference type="SMART" id="SM01049">
        <property type="entry name" value="Cache_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00283">
        <property type="entry name" value="MA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50111">
        <property type="entry name" value="CHEMOTAXIS_TRANSDUC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0807">Transducer</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="15"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="195"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="domain" description="Methyl-accepting transducer" evidence="9">
        <location>
            <begin position="274"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="296"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC94798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="519" mass="56303" checksum="192793B1E153EFC9" modified="2018-07-18" version="1">MHKLMNSFQIRTRLLLINALILIGVALMTMVSLYSLRASMMEERSAKIVSVIDSATSVVNHFHQLQQEGKLTEAQAKEQALGVLRAVKYEGSNYVFIYDTDGMKLAPMPAPEMAGKSFKDLKDSTGKYFIQEMLDDAQSKGFGFVAYQFPKAGQTEELPKLSYISYFTDWKWMLGTGVYIDDVNHKFYASARTNVGMGIAMLIVISFITVMISRGILGQLGGEPNYAVEVVTQVAQGNLTMRANLHPTDKTSLLAQLQRMIEELRQLLLLVRNASESIDSAATEIAQGNLDLSGRTESQSASLEETASSMNQLTSTVRQNSESARQASDLAHTASKVAIHGGSVVRNVVVTMESIKNSSSKIVDIISVIDSIAFQTNILALNAAVEAARAGEQGRGFAVVASEVRALAHRSAAAAKEIKELIQQSVENIQSGATLVDDAGKAMDEIVNSVKSVTEIMTEIAQASKEQTQGIEQVNSAIAEMEGVTQQNAALVEEAAAAAQSMRDQSRSLVESVNTFRLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4B5</accession>
    <name>A0A2S9H4B5_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Glutamate dehydrogenase</fullName>
            <ecNumber evidence="2">1.4.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_0003</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H2O + L-glutamate + NAD(+) = 2-oxoglutarate + H(+) + NADH + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:15133"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.4.1.2"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.4.1.2" evidence="2"/>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94808">
        <property type="protein sequence ID" value="PRC94808"/>
        <property type="gene ID" value="S2091_0003"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004352">
        <property type="term" value="F:glutamate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019551">
        <property type="term" value="P:glutamate catabolic process to 2-oxoglutarate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminiacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028971">
        <property type="entry name" value="NAD-GDH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007780">
        <property type="entry name" value="NAD_Glu_DH_bac"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43403">
        <property type="entry name" value="PTHR43403"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05088">
        <property type="entry name" value="Bac_GDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036761">
        <property type="entry name" value="GDH_Mll4104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="SSF53223"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC94808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="1578" mass="173455" checksum="A506E9B3E2C35422" modified="2018-07-18" version="1">MRQAQELRKQTLTLVQANNAQNNPSVSALLETWLSSLEEDDLAGILPASLASMLWEGFTSAASWTPAQGCQINAMAYQDGRGGRATALLILNPDMPYLVDSIVMALRSQRVVSRAVLNSVLAVQRDAAGKVLQVEKAKATKDSKAGLESIVVCLLTEQIKEPEITSLLGHLKMSVGDAADVRHDAPALSAKMLQLADEVEACANDGKEAGAFLRWADNIGFETFGYVSYQVQPETRELVRDVSSALGVLKNRSHPIYGNCLKSIPGDFDTLFGREHTLSVVKADVQATLYRDQQLDFIGVRNINAQGVLLGEHCLVGLFSRAATATALADLPFARVRIAKVLQMAGVRPEGFRAEKFLEILESLPRVEVLEAQPEWLAEVSSAAVALFKQPRAKVFARRDVYGRHLNVLVYMPRELYSANLAETLADTLQEVVGASSVRVETLLADGPLARLYLIAKAARPDLDLENDIQLPLLGVLEGWHTTFNNLVDSVEEASLRVGLRKLCSELPADYIAVTSPVTAYHDLSGIMHNAGSDRIKVRVETTQPVSIRLQSLRTVPALSNMLPAMHNAGVVIEREQTYQIAEDADSNSGNIYVTCLSLDEASAEKLMQPGVAKVAQELFESLLNNEAEDGRMNALVIEAGMRSMEVQVIRAYASYWRQAGCRFSIRYMADCLKKQAHYVRQLTDAFLLRFDPTLDQQQREAGTAALHAIIEKLTDINHADSEDILRTLAELMLATLRTSYFQSKQLNDIILFKFDTTKLSWLPQPRPFREIFVFSRRFEGVHLRGGPVARGGLRWSDRMEDYRTEVLGLVKAQMVKNAVIVPAGAKGGFVCKMVPKDTNGISSREMVAREGEAVYRLFIAGLLDLTDNRQQGKMIHPEQTVCYDDADPYLVVAADKGTATFSDIANGIAVERGFWLGDAFASGGSNGYDHKKLGITAKGAWEAVKRHFYELGHDLNTTPITMTGVGDMSGDVFGNGLLLSRQIKLVAAFDHRHIFIDPTPDVKASFEERQRMFALPRSSWEDYNKMLISAGGGVYPRDARSITLSLQAQQALHTEAKTVTPEQLLHIILMANVDLFYNGGIGTYIKASTESHAQVKDRANDAIRVDGNVMRCKVVAEGGNLGATQAGRIEFALKGGRIFTDAIDNSAGVDCSDHEVNVKIWLDSEVNAGMIDEAERNSMLNKITLDIEDLVLRDNTQQTRLLVREEQAQHIEKMQDAYANLVRHLEAEGVLSRELEQLPTELELARRKEAGIGLTAPELAVVVANVKNRYKGILSGLPLTGNSWAKSMLTPYFPAALVATRNGLDHPLANPILGTVLANEAVNRCGPIMLVELAEKYQVAESEVILAWSQAWAALNLAPLFDTLDAHALLEPRDVSKALDERCRLLQRSLIEGVLSVPKNAASGNLAELTALFSQQNSVAPLLSKFVTEAKPFPRACQTVEALIDMADFLFSALGTPRTEGLDLAVFLQIGLQLRQQSGIAQLEPMLMQSNVTPLRTHALNALRRAQQRLLELVLLKMPKIQDRLETEQLICHINAVLTQVGIQVKTVQNEQPSLETAVLEVWALSEAATATSMDCV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4D9</accession>
    <name>A0A2S9H4D9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0806</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94803">
        <property type="protein sequence ID" value="PRC94803"/>
        <property type="gene ID" value="S2091_0806"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="97" mass="11303" checksum="B94259055CAF8FA5" modified="2018-07-18" version="1">MTRQNQTNSNRHTQVNYPISIKSIKLHKSRNGYEFNEDDPYWILNKNITVNVCNVRDKLDEEFKQGFTLTLVNYAKFLSAAHTANIGQRMNELLVSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4G2</accession>
    <name>A0A2S9H4G2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Carbohydrate binding domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_0064</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94869">
        <property type="protein sequence ID" value="PRC94869"/>
        <property type="gene ID" value="S2091_0064"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003610">
        <property type="entry name" value="CBM_fam5/12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036573">
        <property type="entry name" value="CBM_sf_5/12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="SMART" id="SM00495">
        <property type="entry name" value="ChtBD3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51055">
        <property type="entry name" value="SSF51055"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015624535" evidence="3">
        <location>
            <begin position="20"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-3" evidence="4">
        <location>
            <begin position="54"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-3" evidence="4">
        <location>
            <begin position="139"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="106"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="190"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="111"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="195"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC94869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="527" mass="53535" checksum="A0B20667A35FE69D" modified="2018-07-18" version="1">MEWNNKGALALVLSSGILAACGGGSSPSSQNTSATAHEATSHAATIKVTTPGCSPAWIDGSTYAAGAIVSYSGSNYTALVAQTDYSGAGWNPSVLSLWSSNGVCVSGTTPTPTPTPTPTPTPTPTPNPTPTPTPTGTCDSAWVATTAYNSGNQVSYSGVNYQANWWTQGNTPSSNSGAAGSGMPWTVLGSCGGTTPPTPPTPPTPPTPPTPPTPPTKPLPSGLILSPYKDVTINMNWNTNVMATAVTGAAQPVLSVIPAKLQTLTLAFATGECGAETWGGIAGSALASANVQAMVAAGKTYILSTGGAAGSFTCSTDAGFATFISRYNSANLIGIDFDIEAGQSQADINNLIQRVKVAQISYPKLRFSFTIATLAAVNGQDLGSMGITVMNSIKSAGLTNYLINLMVMDYGSASATNCVLGSNGLCDMGLSANTAATNLNANWGVPFKQIELTPMIGGNDATDEVFTLANAATVSAFALQNGLAGVHFWSLDRDVDCAPGYASSVCNSYGQAGVFGFTNAFINALGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4K1</accession>
    <name>A0A2S9H4K1_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Chaperone protein DnaJ</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">dnaJ</name>
        <name evidence="13" type="ORF">S2091_0109</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="8">Binds 2 Zn(2+) ions per monomer.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="8">The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the DnaJ family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94914">
        <property type="protein sequence ID" value="PRC94914"/>
        <property type="gene ID" value="S2091_0109"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031072">
        <property type="term" value="F:heat shock protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009408">
        <property type="term" value="P:response to heat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10719">
        <property type="entry name" value="DnaJ_zf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01152">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012724">
        <property type="entry name" value="DnaJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002939">
        <property type="entry name" value="DnaJ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008971">
        <property type="entry name" value="HSP40/DnaJ_pept-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001305">
        <property type="entry name" value="HSP_DnaJ_Cys-rich_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036410">
        <property type="entry name" value="HSP_DnaJ_Cys-rich_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01556">
        <property type="entry name" value="DnaJ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00684">
        <property type="entry name" value="DnaJ_CXXCXGXG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="SSF46565"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49493">
        <property type="entry name" value="SSF49493"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57938">
        <property type="entry name" value="SSF57938"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02349">
        <property type="entry name" value="DnaJ_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51188">
        <property type="entry name" value="ZF_CR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0143">Chaperone</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 8" id="KW-0235">DNA replication</keyword>
    <keyword evidence="2 8 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0677">Repeat</keyword>
    <keyword evidence="6 8" id="KW-0346">Stress response</keyword>
    <keyword evidence="5 8 9" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 8 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="J" evidence="11">
        <location>
            <begin position="5"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="domain" description="CR-type" evidence="12">
        <location>
            <begin position="137"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="repeat" description="CXXCXGXG motif" evidence="8">
        <location>
            <begin position="150"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="repeat" description="CXXCXGXG motif" evidence="8">
        <location>
            <begin position="167"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="repeat" description="CXXCXGXG motif" evidence="8">
        <location>
            <begin position="189"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="repeat" description="CXXCXGXG motif" evidence="8">
        <location>
            <begin position="203"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="CR-type" evidence="9">
        <location>
            <begin position="137"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="25"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="356"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="357"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="150"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="153"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="167"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="170"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="189"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="192"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="203"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="206"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PRC94914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="378" mass="40760" checksum="057889CA6B1C4DCE" modified="2018-07-18" version="1">MAKRDFYEILGVAKNASEDEIKKSYRKMAMKHHPDRNPDSKQSEEKFKEAKEAYEMLSDPKKREAYDRYGHAGVDPNMGGGGGGGGPGGFADAFGDIFGDIFGGGRGGGGRSAGPQVYRGADLRYNLEISLEQAANGFDTTIRVPSWDECDPCHGTGAKPGTSPITCTTCGGHGQVRMQQGLFSIQQTCPKCHGMGKIIPEPCTSCLGVGRIKRNKTLEVKIPSGIDDGMRIRSSGNGEPGMNGGPPGDLYVEIHTKPHAVFQREGDDLHCEMPISFAKATLGGEIEVPTLSGKASFTIPEGTQTGKTFRLRSKGIKGVRSGFPGDLFCHVVIETPVKLTDKQKDLLRDFELLTSEGGSKHSPQSKSWMEKVKSFLSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4L9</accession>
    <name>A0A2S9H4L9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0076</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94881">
        <property type="protein sequence ID" value="PRC94881"/>
        <property type="gene ID" value="S2091_0076"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="61"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="88" mass="10084" checksum="B6F481005D82F027" modified="2018-07-18" version="1">MLDTGQHLAILSISAALGAVYVIPTFRKSNYFILICFFIFSYFMVLGYLNPIIQDLFDRLRSGFITGVIVILLGLISSWIKNKWPNFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4Q4</accession>
    <name>A0A2S9H4Q4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Thioesterase-like superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0157</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94962">
        <property type="protein sequence ID" value="PRC94962"/>
        <property type="gene ID" value="S2091_0157"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="185" mass="21136" checksum="6B162C7A44149D98" modified="2018-07-18" version="1">MNLWFRLIWMLLTVRWRKPATIFDTTSLSMRVLPNDLDFNGHVNNGRYFTIADIGRMDFVLRTGAMRIAIEQRALPIVGDAMAKFRKDLKPFERYELQTRLLGWDEKWIFMEHCFVCRGRVAAVIAMRGLFRAKQGSLPPSAFLAELGITTASPPLPDWVRAWSQSCDSLGGVLREAEATADKVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4R1</accession>
    <name>A0A2S9H4R1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Bacterial extracellular solute-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0167</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94972">
        <property type="protein sequence ID" value="PRC94972"/>
        <property type="gene ID" value="S2091_0167"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006059">
        <property type="entry name" value="SBP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01547">
        <property type="entry name" value="SBP_bac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015534975" evidence="1">
        <location>
            <begin position="22"/>
            <end position="417"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="417" mass="44189" checksum="D1421678A4217E09" modified="2018-07-18" version="1">MKLTKLAQAVLVTTTLFAATAAVQATEVEVLHYWTSGGEAKSAAELKKMMEAKGITWKDFAVAGGGGENAMTALKARVIAGSAPTAAQIKGPSIQEWGNEGVLANIDAAAIDGKWDANLPKVVSNIMKYQGHYVAAPVNVHRVNWLWINPDVLSKSGAKVPTNFDEFFAAADKMKKAGFIAVAHGGQPWQDATVFESVALGVGGAEFYKKALVQLDPATLTGPTMIKTFDTLAKIKTYIDKDSAGRDWNLATAMVINGKAGMQFMGDWAKGEFTAAGKQPGKDFLCVAAPGTEKDFSFNIDSLAMFKMTDPAKQKAQLVLATAVMSPEFQEVFNLNKGSIPARAGVSRAKFDSCAIKSMNDMEASSKSNELVPSFAHGMAIDSAKAGAIQDVIAKFMNSTMTSQAAVQALAKAAKTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4Y2</accession>
    <name>A0A2S9H4Y2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0131</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94936">
        <property type="protein sequence ID" value="PRC94936"/>
        <property type="gene ID" value="S2091_0131"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="260" mass="27804" checksum="18EAE4ED5EF92C32" modified="2018-07-18" version="1">MQNLVSGLVSELVSELTRLYLPTSSLSAEALAQHLLGHKTLAINLATEDGLTGAVVITFDKVGDSDDAQHWSRLCTVANALQSEFGFPAPAVSISGANGYGLWLSFEVPVPVAQAQKFLELLSKAYFPDMELGAVSAPVELPPCLHQSTGKWAAFIHPGMGASFADESGLEMAPPIAGQLAFLTGLHSISEVQFLSALKALQQLHGAAAMDKMDNIEKIPPSAHVATSDNLLLRDATLEDIVNFLHSKNIEPTFRHLIPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5B5</accession>
    <name>A0A2S9H5B5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Acyl carrier protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0353</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95158">
        <property type="protein sequence ID" value="PRC95158"/>
        <property type="gene ID" value="S2091_0353"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="2">
        <location>
            <begin position="7"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="1">
        <location>
            <position position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC95158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="90" mass="10173" checksum="2E89C66A2FF5B6E2" modified="2018-07-18" version="1">MIMISEMSKDELYVWVVDLLAQMFELDKSSLTPQSNLYADLDIDSIDAVDLAVKLKQLTGKRLAPEVFKEIRTIEDVVNSLSELTPEQLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5G4</accession>
    <name>A0A2S9H5G4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein conserved in bacteria (DUF2063)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0425</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95230">
        <property type="protein sequence ID" value="PRC95230"/>
        <property type="gene ID" value="S2091_0425"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.690">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018640">
        <property type="entry name" value="DUF2063"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044922">
        <property type="entry name" value="DUF2063_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09836">
        <property type="entry name" value="DUF2063"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF2063" evidence="1">
        <location>
            <begin position="14"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC95230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="263" mass="28828" checksum="3D2977EB4EA61005" modified="2018-07-18" version="1">MRAANLVTPQLTTLQHDFASALINLNSLDPALASFKGDPDLNRERFGLYRGNLIAIWQQTCVNAYPVLQQLVGAEFFGDLARAYGLNHASQSGNLAEFGAALSSFIATLENCRAYPYLSDVAALEWQVHRSYYLEQRSPATLAQLAGFAPELLGDLQFTLQPSCVLLESPWAVVDIWQAHQGTNTPFPEQLASATYCLIWREHHQTNISAISAASYAALQALNAGQPLGQAFESALAIDPEFALPTELADWFGKQLFSNISHN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5G7</accession>
    <name>A0A2S9H5G7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0376</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95181">
        <property type="protein sequence ID" value="PRC95181"/>
        <property type="gene ID" value="S2091_0376"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022550">
        <property type="entry name" value="NTP_transf_8"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12281">
        <property type="entry name" value="NTP_transf_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC95181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="348" mass="38049" checksum="42F72C5489CE60B9" modified="2018-07-18" version="1">MKQLYSAFQATYHTEFENLFQWAQTQEIIYIGTPGRIEERLRGTDTFFYHRFYDASGNQSEKYIGGPSGTPEGELALKNVQDRISSADMVVQSVRELRKLGFAVIEDKAGATLAALHNHGLFSGGLTLIGSHAYGAILNKLGVKAPSYLTEDIDTVRSNPLSLATTPQMSLLDILQTSGLPFIKAKTGLRSGDKSETYKLPGREKLLVDLLVNGSDIGAPILVPEFEAYAQAVPHLDYLVDGRLESVILSKNYAVPVYTPNPARFAIHKLFSSLSRINQPAKSGKDILQAATVICAMEDKYPGDIEDALNAFPDSGKGLMLKGAEKALPIVQSHSEQYGDVLRRLIDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSA8</accession>
    <name>A0A2S9GSA8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4704</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000046">
        <property type="protein sequence ID" value="PRC90597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90597">
        <property type="protein sequence ID" value="PRC90597"/>
        <property type="gene ID" value="S2091_4704"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="123" mass="13680" checksum="DDD81DA3E4ABDFC0" modified="2018-07-18" version="1">MSDPSGLDPKSEPVPGTNYDYRIDSKNLQPNQQPHAHIYDSKGNEIVVINKDGTGSHGSCPDKLPKNKKLIKFLLSKGFLLTFAGDLIFLEDLVNSVGRSVDPYNPYYYYDPKDVPKPGIVNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSJ2</accession>
    <name>A0A2S9GSJ2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4631</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000039">
        <property type="protein sequence ID" value="PRC90681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90681">
        <property type="protein sequence ID" value="PRC90681"/>
        <property type="gene ID" value="S2091_4631"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007236">
        <property type="entry name" value="SlyX"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04102">
        <property type="entry name" value="SlyX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="6"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="68" mass="7950" checksum="28D99304B24FF371" modified="2018-07-18" version="1">MIENRLENIEIKLTRQEDLLDTLNQQVYLQQKKIDELELLCTALIQRFKEVSSNSGQAGLAHDRPPHY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSL3</accession>
    <name>A0A2S9GSL3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ABC-2 family transporter protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_4594</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000038">
        <property type="protein sequence ID" value="PRC90701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90701">
        <property type="protein sequence ID" value="PRC90701"/>
        <property type="gene ID" value="S2091_4594"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032688">
        <property type="entry name" value="ABC2_membrane_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000412">
        <property type="entry name" value="ABC_2_transport"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12679">
        <property type="entry name" value="ABC2_membrane_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51012">
        <property type="entry name" value="ABC_TM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="27"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="185"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="235"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="264"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="293"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="349"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC90701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="382" mass="41862" checksum="903E666B43F6EC89" modified="2018-07-18" version="1">MSTISRRRLIALCRKESYQIVRDPSSILIAFVLPVILLFIFGYGINLDTNRVRIGLVVEDSGVEAQRFADVLTGSPYLEVHTGHSRSAMQDQLQNGSVRGMVVLGSDFSAKVQQAQTHQTQDQAQIQLLTDGAEPNTANFLSSYLQGSLQIWLTQRASDRGLPDLAITSLEPRYWFNPTTVSRNYLVPGSISVIMTVIGALLTSLVVAREWERGTMEALLSTSVTRSELLLSKIIPYYMLGMIAMSLCVLVATVLMGVPLRGSYWMLFIVSSLFLGSSLGLGLLLSTVTRNQFVAAQGALVAAFLPATMLSGFVFEIASMPLPVRAISYLIPARYFVSALQTIFQAGDIWPVLLLNTGFLLLSALFWLGLTALKTARRLDGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSN4</accession>
    <name>A0A2S9GSN4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Heavy-metal-associated domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_4553</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000037">
        <property type="protein sequence ID" value="PRC90727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90727">
        <property type="protein sequence ID" value="PRC90727"/>
        <property type="gene ID" value="S2091_4553"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00371">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006121">
        <property type="entry name" value="HMA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036163">
        <property type="entry name" value="HMA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00403">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55008">
        <property type="entry name" value="SSF55008"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50846">
        <property type="entry name" value="HMA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015603197" evidence="1">
        <location>
            <begin position="22"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="domain" description="HMA" evidence="2">
        <location>
            <begin position="25"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC90727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="110" mass="11990" checksum="4B7D0CFC0FF3213F" modified="2018-07-18" version="1">MKKIIGTVILATIVMANTAQAAVQTIKAEVNGMVCAFCAQGIDKKLRELPQIKAVYVNLKHKIVAVELKEDQTLSESTVKDVVKNAGYDVVNIQTVDQTAQQIKESFGKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSR2</accession>
    <name>A0A2S9GSR2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glutathione S-transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_4576</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000037">
        <property type="protein sequence ID" value="PRC90750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90750">
        <property type="protein sequence ID" value="PRC90750"/>
        <property type="gene ID" value="S2091_4576"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13417">
        <property type="entry name" value="GST_N_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="SSF47616"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GST N-terminal" evidence="1">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="2">
        <location>
            <begin position="87"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC90750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="219" mass="25054" checksum="D9B7C91C6EF25139" modified="2018-07-18" version="1">MTLALYGHPFSSYTQKVLIALYENNIPHEFRSLGPDTPQHSAEWLRRWPLRKFPLLVDGERNVAETSIIIEYLHLSYPGPVRLLPADPMAALEVRFLDRFYDLHVMSPVQHAVDGALTGDPVKRQEGLTLSMEKLERAYAWLEGQLAERTWAAGSDFTLADCAAAPSLFYADWTHRISEAFPLLRAYRARLLTRPSFARAVDEARQFRHYFPLGAPDRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSU3</accession>
    <name>A0A2S9GSU3_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 10">Flagellar biosynthetic protein FliR</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">S2091_4537</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 10">Role in flagellar biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cell membrane</location>
            <topology evidence="10">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Bacterial flagellum basal body</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the FliR/MopE/SpaR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000036">
        <property type="protein sequence ID" value="PRC90789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90789">
        <property type="protein sequence ID" value="PRC90789"/>
        <property type="gene ID" value="S2091_4537"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009425">
        <property type="term" value="C:bacterial-type flagellum basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044780">
        <property type="term" value="P:bacterial-type flagellum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006605">
        <property type="term" value="P:protein targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006303">
        <property type="entry name" value="FliR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002010">
        <property type="entry name" value="T3SS_IM_R"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30065">
        <property type="entry name" value="PTHR30065"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01311">
        <property type="entry name" value="Bac_export_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00953">
        <property type="entry name" value="TYPE3IMRPROT"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01400">
        <property type="entry name" value="fliR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0975">Bacterial flagellum</keyword>
    <keyword evidence="5 10" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="11" id="KW-0966">Cell projection</keyword>
    <keyword evidence="11" id="KW-0969">Cilium</keyword>
    <keyword evidence="11" id="KW-0282">Flagellum</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="12"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="44"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="73"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="99"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="129"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="170"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="215"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU362071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC90789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="256" mass="27337" checksum="2464BF8827CD6F1D" modified="2018-07-18" version="1">MLSISSDQLIIWVNSFIWPLTRILGLIAIAPIFGNAAIPVPMKISFGVVLALLVAPTLHNLPLIDPISLPGMLILIEQFVIGVAMGFTIQVVFGSVDLAGNLIGMSMGLGFASFFDPQTRGNTPAISQFLTLVTTMLFLSLNLHLALLSTLVESFTKLPIGVDLTLQPGIWLHIVSAASVIFSSGVQLALPIIAALLVTNIALGILTRAAPQLNIFGIGFPITMTVGFLMLFIIIPYLALPLQKILEFGIQLAALR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSW3</accession>
    <name>A0A2S9GSW3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Tetratricopeptide repeat</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4458</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000035">
        <property type="protein sequence ID" value="PRC90795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90795">
        <property type="protein sequence ID" value="PRC90795"/>
        <property type="gene ID" value="S2091_4458"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC90795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="217" mass="24818" checksum="B83E5F6FC2659266" modified="2018-07-18" version="1">MKKIILAIILCLSGITWSYGNNNLIDMTNKENIDLFNQHYKLGSEYLNGNVKLGDYDGKEIREKNRVDNLKKAIHEFDQCLEIKPDHWQSIFFKALAFQALGNHTASLSLMEQGIKLQPQNYVLYKEASLEAIHNHDISKALNYSKMATEVRKDDPQLLGNYAMNLLISGQDKESQQTIKYALSVAPDDRFNQKLQNIIKNVVSGKRSRPTVENVFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSY3</accession>
    <name>A0A2S9GSY3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative periplasmic or secreted lipoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4478</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000035">
        <property type="protein sequence ID" value="PRC90815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90815">
        <property type="protein sequence ID" value="PRC90815"/>
        <property type="gene ID" value="S2091_4478"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007055">
        <property type="entry name" value="BON_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014004">
        <property type="entry name" value="Transpt-assoc_nodulatn_dom_bac"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04972">
        <property type="entry name" value="BON"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00749">
        <property type="entry name" value="BON"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50914">
        <property type="entry name" value="BON"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BON" evidence="1">
        <location>
            <begin position="46"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="domain" description="BON" evidence="1">
        <location>
            <begin position="124"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="192" mass="20077" checksum="5A5E77A593EBBE80" modified="2018-07-18" version="1">MTNYPNCTVYVNAIIASVFLATLSGCNNSQVASDSAPHITIGNQIDDSVVVAKVRSALLANDEIKSLDIKVTVNKGVVMLSGFVDNQSQIDRGSAVASAVEGVKSIDNKLSIKEGKQTIGNKVDDSVITAGVKAALLNDSTMKSLDVSVTTRKGEVQLSGFVDNDIQLARAVVVAGDVDGVTSVVNHMNVKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSZ0</accession>
    <name>A0A2S9GSZ0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Gkycosyl transferase family 4 group</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_4423</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000034">
        <property type="protein sequence ID" value="PRC90842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90842">
        <property type="protein sequence ID" value="PRC90842"/>
        <property type="gene ID" value="S2091_4423"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022623">
        <property type="entry name" value="Glyco_trans_4_3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12000">
        <property type="entry name" value="Glyco_trans_4_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4_3" evidence="2">
        <location>
            <begin position="26"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="211"/>
            <end position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC90842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="409" mass="46243" checksum="9CEE988682FB504C" modified="2018-07-18" version="1">MKILFIHQNFPGQYLHLARHLGAMPGNDVVFITQRTDADLPGVRKVLYKPQREVTRGVHHYLRETEAGVLNAQNVARVALSLKEAGFVPDVILGHNGWGEIWYLKEVFPTTPLIGYFEFFYRQHGADVGFEPGPAAIFDVGPRIRTKNIGNLLALDAADYGQCPTQWQKSLYPKEYQSKLHIVHEGVDTQLLVPDQAARFTIPNTDITLTTDDEVVTYVSRNLEPYRGFPSFMRSLPTILAQRPNAQVLVVGSDEVSYGPKLAGDKNFRQLLLEELGNSIDLKRVHFLGKVPYSSFMKVLQVSTVHVYLTYPFVLSWSMLEAMSIGCVIVGSRTQPVEEVIRDGENGVLVDIFSPEEITSRVVDVLTDRKAFEQIRQRARQTIVENYDLRSICLPAQLRLMKMAAQRML</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GT53</accession>
    <name>A0A2S9GT53_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">KWG Leptospira</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4369</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000033">
        <property type="protein sequence ID" value="PRC90876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90876">
        <property type="protein sequence ID" value="PRC90876"/>
        <property type="gene ID" value="S2091_4369"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032774">
        <property type="entry name" value="WG_beta_rep"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14903">
        <property type="entry name" value="WG_beta_rep"/>
        <property type="match status" value="9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC90876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="466" mass="51258" checksum="E02A35C9C0D6F4EF" modified="2018-07-18" version="1">MKSKSFFAILIFLTFITISSVNAISPRLPKLGKFGLVNEKGDLVVKPIYDQIGEFSKNGLAVVHLNGRAGFINTKGEVVISIKFEDAGDFAINDLAAVKVGNYWGYIDSSGAYAIEPKFEIKFYHSEFLRHVQFSSQGLAAAVKGDEWGYIDKHGQWVIQPQFHDVTVFFDDGLALVESNWKWGFIDQKGTIVIPIKFDKAYRFSLNGLAPIKIEDKWGYINKSGEIVIPTDFSTAYGFGTEIPGNYARACIKESCGFIDQLGKFIPYLNMDKYILAGYSNGFIQIQDRENLKHGFMNLMGEIVIEPIYGSTGGFSKDGLAPVSLNGLWGYLNTKGEFAISAQFIYAGSFSSNGIAPAQLDGKFGYINKMGAPIISPQFDNAGEFNEFGLAKVEIKGIENQTIYSNTTLPEHSCNAEKTDFCSTYCSARCPATKKAVCTKGIVHIPDPNIDAGIGYCVKEPSCTCE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GT60</accession>
    <name>A0A2S9GT60_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Kynurenine formamidase</fullName>
            <shortName evidence="7">KFA</shortName>
            <shortName evidence="7">KFase</shortName>
            <ecNumber evidence="7">3.5.1.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Arylformamidase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">N-formylkynurenine formamidase</fullName>
            <shortName evidence="7">FKF</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">kynB</name>
        <name evidence="8" type="ORF">S2091_4402</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 7">Catalyzes the hydrolysis of N-formyl-L-kynurenine to L-kynurenine, the second step in the kynurenine pathway of tryptophan degradation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>H2O + N-formyl-L-kynurenine = formate + H(+) + L-kynurenine</text>
            <dbReference type="Rhea" id="RHEA:13009"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:57959"/>
            <dbReference type="ChEBI" id="CHEBI:58629"/>
            <dbReference type="EC" id="3.5.1.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="7">Binds 2 zinc ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="7">Amino-acid degradation; L-tryptophan degradation via kynurenine pathway; L-kynurenine from L-tryptophan: step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the Cyclase 1 superfamily. KynB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.9" evidence="7"/>
    <dbReference type="EMBL" id="PUGF01000033">
        <property type="protein sequence ID" value="PRC90909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90909">
        <property type="protein sequence ID" value="PRC90909"/>
        <property type="gene ID" value="S2091_4402"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00333">
        <property type="reaction ID" value="UER00454"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004061">
        <property type="term" value="F:arylformamidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004328">
        <property type="term" value="F:formamidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019441">
        <property type="term" value="P:tryptophan catabolic process to kynurenine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01969">
        <property type="entry name" value="KynB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007325">
        <property type="entry name" value="KFase/CYL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037175">
        <property type="entry name" value="KFase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017484">
        <property type="entry name" value="Kynurenine_formamidase_bac"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31118">
        <property type="entry name" value="PTHR31118"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04199">
        <property type="entry name" value="Cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102198">
        <property type="entry name" value="SSF102198"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03035">
        <property type="entry name" value="trp_arylform"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7" id="KW-0823">Tryptophan catabolism</keyword>
    <keyword evidence="5 7" id="KW-0862">Zinc</keyword>
    <feature type="active site" description="Proton donor/acceptor" evidence="7">
        <location>
            <position position="59"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="19"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="49"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="53"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="55"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="159"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC90909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="209" mass="22598" checksum="0F38D76CBF75ACA3" modified="2018-07-18" version="1">MSKKMWDISPTLHPGLPVWPGDTPYQSETTWEIANGCPVKVSKISMSSHTGAHCDAPSHYGVNAKAIDEVALDAYIGACRVIDLQGTRVVQPEQLTAHLNQIPARVLLRTYTTTPQQWDDQFPCISAAAIHLLAEHGVQLIGIDSPSLDPQDSKTLDAHHAVEKHGMAILEGIVLDEISAGDYELIALPLKFAGLDASPVRAILRSLIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTE6</accession>
    <name>A0A2S9GTE6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Phage tail tape measure protein, TP901 family, core region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_4279</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000031">
        <property type="protein sequence ID" value="PRC90983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90983">
        <property type="protein sequence ID" value="PRC90983"/>
        <property type="gene ID" value="S2091_4279"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010090">
        <property type="entry name" value="Phage_tape_meas"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10145">
        <property type="entry name" value="PhageMin_Tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01760">
        <property type="entry name" value="tape_meas_TP901"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="542"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="576"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="696"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="722"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="domain" description="PhageMin_Tail" evidence="3">
        <location>
            <begin position="246"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="68"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF10145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC90983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="917" mass="97509" checksum="3557FFF7451B1852" modified="2018-07-18" version="1">MADLKLQVILSALDRITAPLKAIRGAAAPTSDAIKATSDRLKDLNAQQDKISQFRELKKGLNTTSIELRAAKQRVSELGTQLTTLKSQSSPAAGAVKKLSSEYKKAQASVEKLTTTYRTNLETNKTVRNALLATGISTKKLGEAQTWLKNSIAYTNAELTSQKKKLADVATQQTRVAAMRAKYAKTKDMAGKAAMVGATSAAIGGGVLMGARQMLTPGIEFNEAMSRVQALSRVDKKSDDFKAMRQQARDLGANTSYTATEAAQGQGYLAMAGFKPADILQSMPGVLSMAKAGGSDLARAADISSDILTSFGLQADQMTRVGDVLTMTFTTANTDLEMLGDTMKYVGPIARAAGMSLEQASAMAGLLGNAGIKSSQAGTTLRSMLLRLAAPTSAAGKALKELSVSSQDLKGNVRDIPSILRDVAKATEKMGSGQRLGFLKRIFGEEPAAGMAELIDKQGADGIGRYVAIVENSKGVAAKTAQVMADNLSGDLKTLSSSWENLGITMSDAIDVPMRKVTDRITDILRVTDKWMKDNPKLAETLLMITLAVGAVLLVLGTLTIALAAIVVPMAAVSTAFGVLGITAGIALAPLLLIIAGIAVFAGLAYLVYQYWEPLKAWFTGFWEGLSDGLAPLGELFSRAFGAMGTVLEPLKPLWDWFVEKFNEAGKWLSELISPLQSTQAELDATTGSGYLFGKWIAGLILLMADVGISIITGMFKSLLTVNAFILNWSPLGIVYKAIAGILRLFGVDMPEQFSEFGSNMIASFIKGIRAQFPMLDALISKFENILPTGKLAIDSKPLSSEQVQQSQQMMDALKLKRPIAPVSNFSEVGGMANHLTQAGAGIRANLTAMPALSFDTRPPVATRPPGSSVMMQGDTNHFTINPAPGMDEAAIAKAVTKALEKQSHQKAARLRSRLAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTI6</accession>
    <name>A0A2S9GTI6_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Succinate--CoA ligase [ADP-forming] subunit beta</fullName>
            <ecNumber evidence="6">6.2.1.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Succinyl-CoA synthetase subunit beta</fullName>
            <shortName evidence="6">SCS-beta</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">sucC</name>
        <name evidence="9" type="ORF">S2091_4302</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>ATP + CoA + succinate = ADP + phosphate + succinyl-CoA</text>
            <dbReference type="Rhea" id="RHEA:17661"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57292"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.2.1.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="6">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="6">Carbohydrate metabolism; tricarboxylic acid cycle; succinate from succinyl-CoA (ligase route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Heterotetramer of two alpha and two beta subunits.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the succinate/malate CoA ligase beta subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.2.1.5" evidence="6"/>
    <dbReference type="EMBL" id="PUGF01000031">
        <property type="protein sequence ID" value="PRC91006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91006">
        <property type="protein sequence ID" value="PRC91006"/>
        <property type="gene ID" value="S2091_4302"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00223">
        <property type="reaction ID" value="UER00999"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004775">
        <property type="term" value="F:succinate-CoA ligase (ADP-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.261">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00558">
        <property type="entry name" value="Succ_CoA_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013650">
        <property type="entry name" value="ATP-grasp_succ-CoA_synth-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005811">
        <property type="entry name" value="CoA_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017866">
        <property type="entry name" value="Succ-CoA_synthase_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005809">
        <property type="entry name" value="Succ_CoA_synthase_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016102">
        <property type="entry name" value="Succinyl-CoA_synth-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11815">
        <property type="entry name" value="PTHR11815"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08442">
        <property type="entry name" value="ATP-grasp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00549">
        <property type="entry name" value="Ligase_CoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001554">
        <property type="entry name" value="SucCS_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52210">
        <property type="entry name" value="SSF52210"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01016">
        <property type="entry name" value="sucCoAbeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01217">
        <property type="entry name" value="SUCCINYL_COA_LIG_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 6 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 6 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 6" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="ATP-grasp" evidence="8">
        <location>
            <begin position="9"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding; shared with subunit alpha" evidence="6">
        <location>
            <begin position="321"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="46"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="53"/>
            <end position="55"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="99"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="102"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="107"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="199"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="213"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="264"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared with subunit alpha</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC91006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="391" mass="41525" checksum="712166D5D0148283" modified="2018-07-18" version="1">MKIHEYQGKEILRKFGVTVPRGIPCMSVEEAVKAAETLGGPVWVVKAQIHAGGRGKGGGVKVAKTLEQVKEYADAIMGMQLITHQTSPEGQKVRRLLVEEGADIKQELYISLVTDRISQRVVLMASSEGGMDIEEVAASHPEKIHQIAIDPTAGLQDAEADDICRKIGVPEASVVDARTQLKGLYAAFMETDASLAEINPLIVTGSGKIIALDAKFNFDSNALFRQPEIVAYRDLDEEDPAEIEASKFDLAYISLDGNIGCLVNGAGLAMATMDTIKLFGGEPANFLDVGGGATAEKVTEAFKIMLKNPGLKAILVNIFGGIMRCDVIAEGVITASKAVSLTVPLVVRMKGTNEEIGKKMLADSGLPIISADTMEEAAQKVVAAAAAFSAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTK0</accession>
    <name>A0A2S9GTK0_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Probable phosphoketolase</fullName>
            <ecNumber evidence="5">4.1.2.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_4240</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the XFP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.-" evidence="5"/>
    <dbReference type="EMBL" id="PUGF01000030">
        <property type="protein sequence ID" value="PRC91052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91052">
        <property type="protein sequence ID" value="PRC91052"/>
        <property type="gene ID" value="S2091_4240"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016832">
        <property type="term" value="F:aldehyde-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01403">
        <property type="entry name" value="Phosphoketolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023962">
        <property type="entry name" value="Phosphoketolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005593">
        <property type="entry name" value="Xul5P/Fru6P_PKetolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018969">
        <property type="entry name" value="Xul5P/Fru6P_PKetolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019790">
        <property type="entry name" value="Xul5P/Fru6P_PKetolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018970">
        <property type="entry name" value="Xul5P/Fru6P_PKetolase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019789">
        <property type="entry name" value="Xul5P/Fru6P_PKetolase_ThDP_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31273">
        <property type="entry name" value="PTHR31273"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03894">
        <property type="entry name" value="XFP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09363">
        <property type="entry name" value="XFP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09364">
        <property type="entry name" value="XFP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017245">
        <property type="entry name" value="Phosphoketolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS60002">
        <property type="entry name" value="PHOSPHOKETOLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS60003">
        <property type="entry name" value="PHOSPHOKETOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0456">Lyase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0786">Thiamine pyrophosphate</keyword>
    <feature type="domain" description="XFP_N" evidence="7">
        <location>
            <begin position="17"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="domain" description="XFP_C" evidence="6">
        <location>
            <begin position="594"/>
            <end position="795"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF09363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF09364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC91052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="804" mass="90439" checksum="3D3E094CC7488DD4" modified="2018-07-18" version="1">MTDQHSESTAPPRDALSPLQLKKMNAYWRAANYLSVGQIYLLDNPLLKKPLTLEHIKPRLLGHWGTTPGLNFIYVHLNRIIKLHDLNVINVTGPGHGGPGLVANTYLEGSYSELYPNILQNESGLKKLFTQFSFPGGIPSHVAPGTPGSINEGGELGYSLSHAYGAAFDNPDLLVACVVGDGEAETGAMATSWHSNKFLNPVRDGAVLPILHLNGYKIAGPTVLARISHEELEQLFRGYGYTPYFVEGDDPEKMHQLMAATLDIVIAEIQRIQDDARLNGFSVRPRWPMIILNSPKGWTGPKIVDGKPVEGTFRAHQVPVAELRNNPEHVAILEQWLKSYHAEELFDKNGRLLPELAELAPRGKRRMGANPHSNGGLLLRDLILPDFREYAIKVPKPGVVDAEATRIQGQFLRDVMKLNTVENNFRLFSPDETASNRWNAVFDVTDRCSTARIIAIDDHVANDGRVMEMLSEHQCEGWLEGYLLTGRHGFFSCYEAFIHIVDSMFNQHAKWLKMAHQIPWRRPIASLNYLLSSHVWRQDHNGFSHQDPGFIDHVVNKKSEVVRVYLPPDANTLLSVTDHCLRSRDYINVIIAGKQPEPQWLDMASAVKHCANGIGIWDWASNDEGIEPDVVMASCGDVPTLESLAAVKILREHFPDLKIRFINVVDLMALQPQIEHPHGLSDQDFDVLFTKDKPIIFAFHGYPTLIHRLTYRRTNHHQLHVRGYKENGTTTTPFDMVVLNDLDRFHLAIDVIDRVPSLGAKAAHAKQFLRGKLLDHKAYIEQYGEDMPEIQNWKWDSGKSGINL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTQ6</accession>
    <name>A0A2S9GTQ6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="9">ATPase component of various ABC-type transport system</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_4174</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000029">
        <property type="protein sequence ID" value="PRC91078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91078">
        <property type="protein sequence ID" value="PRC91078"/>
        <property type="gene ID" value="S2091_4174"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015833">
        <property type="term" value="P:peptide transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013563">
        <property type="entry name" value="Oligopep_ABC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08352">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-1278">Translocase</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="8">
        <location>
            <begin position="14"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="8">
        <location>
            <begin position="311"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="51"/>
            <end position="58"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="352"/>
            <end position="359"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC91078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="569" mass="63316" checksum="BC8EF2AED6DB8C2C" modified="2018-07-18" version="1">MNNKTVANADDMLLNVENLRISFKVNKHESVAAIKGISFTVPQNCTVALVGESGSGKSVSSLAIMGLLPSDSAQIDPNSRITFEGKNLLDLSLAERRKLCGKEFAMIFQEPMTSLNPVFTVGFQIAEVLRLHLNMNAKQAHARTLALLDEVGIPDPKTKIDAYPNQLSGGQQQRVMIAMAIACEPKLLIADEPTTALDVTIQKQIIELIESLRTKHKMSVLFITHDLALVGEIADYVVVMRHGEVREMGAVQQIFEAPKDAYTKALLHCRPSLTTRPWRLPVIDDYMQTAPSDKIHTERPRGLNGSEEIVLEVTNLAKSFFFREGFFGRKEFKAVEDVSFKLARGKTLGVVGESGSGKTTLGLTLLRLHQASGGQAIFDGKDILAMSNNEFMHYKRRIQIIFQNPYASLNPRFTVGQILMEPMHIHRIGSNDAERATMAYQLLDKVSLPAAAFHRYPHEFSGGQRQRIAIARCLTMRPEVLVCDESVSALDVSVQAQVLNLLQDLQEEFGMSYIFISHDLAVVKYIADQVMVMHQGRVVELANSDELYLNPKQEYTRSLLSAIPRGLQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTR1</accession>
    <name>A0A2S9GTR1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4184</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000029">
        <property type="protein sequence ID" value="PRC91088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91088">
        <property type="protein sequence ID" value="PRC91088"/>
        <property type="gene ID" value="S2091_4184"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025449">
        <property type="entry name" value="DUF4194"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13835">
        <property type="entry name" value="DUF4194"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="214" mass="23975" checksum="0D4ED9F530017541" modified="2018-07-18" version="1">MSEPMLEQTPACSNLSSLIIVLLKGVLYQENDVNLWADLLNLQAQVRDYIAVIGLELALDEAEGYAFLRAHSELKDDPASKLPRLVVRRQLSFSVSLLLALLRKKLAEFDASGGQDGNGMRLVLNRNDIIELIRVFLPSASNDAKLTDQIETHINKIVELGFLRKLKASNPSMPAAFEVRRIIKAFVDAQWLAEFDAQLDAYQIHLTATQEEDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GU22</accession>
    <name>A0A2S9GU22_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative protease with the C-terminal PDZ domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_4096</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000027">
        <property type="protein sequence ID" value="PRC91201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91201">
        <property type="protein sequence ID" value="PRC91201"/>
        <property type="gene ID" value="S2091_4096"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027268">
        <property type="entry name" value="Peptidase_M4/M1_CTD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024191">
        <property type="entry name" value="Peptidase_M61"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007963">
        <property type="entry name" value="Peptidase_M61_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040756">
        <property type="entry name" value="Peptidase_M61_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05299">
        <property type="entry name" value="Peptidase_M61"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17899">
        <property type="entry name" value="Peptidase_M61_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016493">
        <property type="entry name" value="Glycyl_aminpptds"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="SSF50156"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015618533" evidence="1">
        <location>
            <begin position="35"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M61_N" evidence="3">
        <location>
            <begin position="51"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M61" evidence="2">
        <location>
            <begin position="318"/>
            <end position="434"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC91201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="643" mass="72578" checksum="56DFC3CACA004DBE" modified="2018-07-18" version="1">MPFSSEHKAISGKLPNAKLIATLLAATAFHVAVAQEIPPPVDKVYPGTIQLDVDVTNLDQKIFKVHERIPVTAGKLTLFYPQWLPGNHAPTGPISQLAGLMLTANGQPVEWKRDTLNMFAFHLTVPANVKFIDADYQFLSPVEGNQGRITATQEIVGVQWNAVVLYPAGYYARGISFKPSVTLPADWKFGTALELAQQVGTQAQFKQTNLDDLIDSPLFAGKYFKRFDLDPGAKVPVFLNVVADRPENLVTKPEQIDAHRALVQQAYKLYGSQHYVHYDFLLSLSDEFTGIGLEHHQSSENGVKPNYFTEWSKTWGTRGLLPHEFTHSWDGKFRRPADLWTPNFNVPMQNSLLWVYEGQTEYWGDVLAARSGLVSVEQTRDTLANIAASYDQRVGRTWRALQDTTNMPIISRRSPLAWVSWQRPEDYYREGQLVWLDVDTKIREMSGEQKSLNDFAHTFFGVENGRHSALTYTFDDVVSTLNAIQPYDWATFLRTRLDGHAKEGPKDGLTRAGWKLAYTEERSEATKSEEEERHVTDYAYSLGFTVGKEGRLDYVAWDGVAFKHGMTIGATLLAVNGRSYKAELLKEVITAAKTSKQPIELLLKKDDRYHTVSIDYHDGLKYPHLVRIEGTPDRLTTILQPLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUG6</accession>
    <name>A0A2S9GUG6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SPFH domain / Band 7 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3904</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000024">
        <property type="protein sequence ID" value="PRC91359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91359">
        <property type="protein sequence ID" value="PRC91359"/>
        <property type="gene ID" value="S2091_3904"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001107">
        <property type="entry name" value="Band_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036013">
        <property type="entry name" value="Band_7/SPFH_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01145">
        <property type="entry name" value="Band_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117892">
        <property type="entry name" value="SSF117892"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PHB" evidence="1">
        <location>
            <begin position="67"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="424" mass="45911" checksum="0862779C7FE1EE20" modified="2018-07-18" version="1">MLNRIKPLVHAVSTTLISAASSGAAGIKSGSRAVISLASGKFSSLVILGVVGAIGYGVYNHPPVSYIKRGQIGVRINQLTGSSELIHEGMVVIVPGVVELRQYSLLDQLYRPVKSSKSDGEAPFQSIEGLSLGVDLTIRYALDSSRLAGMSKSLPQDINGEIVEPLVQGVIYKAFTRYTVREIFSSKRQEIQQQIEAELKPKLAADGILLRSVMMGKIDLPQDYKNGMEKLLSAELETEKMKYTLDLKDKQVKQTALEAEADKVRRETAAEAAGNEQIIAAKAQEEAMTHVLPFKQKQIEQRQYEAEAEKVARIKTSEGTAQARVIEATGEADSRRKLADAEAYRQDLVGKVASAQLERDGELLTKHPLLIQKTMADKLSDKISVIIAAPPANGGFIGSALLGMGNKTEQAQAPAVETSNQEGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUI9</accession>
    <name>A0A2S9GUI9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">YGGT family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3919</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the YggT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000024">
        <property type="protein sequence ID" value="PRC91374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91374">
        <property type="protein sequence ID" value="PRC91374"/>
        <property type="gene ID" value="S2091_3919"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003425">
        <property type="entry name" value="CCB3/YggT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33219">
        <property type="entry name" value="PTHR33219"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02325">
        <property type="entry name" value="YGGT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="105"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="156"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="184" mass="20604" checksum="F6321328336A84EE" modified="2018-07-18" version="1">MLYNLFSLVLDTVAGLFAGVLLLRFWMQIVRVRPPQQIAQFTFQLTDWLVKPLRRVIPGVGGFDWASVLGAYAIALLATAIKVWMVMGYLPASLFLLALFSVLQWIIYGWTALLVFEVIFSWINPHAPLAPFVQALNAPLLRPIRQVLPLLGGLDISPMVLFLLLQFAGKMLAYLFVMSGMIPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUJ2</accession>
    <name>A0A2S9GUJ2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3918</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000024">
        <property type="protein sequence ID" value="PRC91373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91373">
        <property type="protein sequence ID" value="PRC91373"/>
        <property type="gene ID" value="S2091_3918"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="136" mass="15035" checksum="A903A1A53C7880DB" modified="2018-07-18" version="1">MKKILIGMLASLLAYSVCYSVYADFVVVVNAKNPTISISKEQIAQYFLGSTNTFSPIDLAEGSPIRVEFYKTITDKDPSQVRAIWSKLVFTGKAKPPKQFNTSEEVKKQIGSDINAIGYMEKSAVDSSVKIIYPVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUR5</accession>
    <name>A0A2S9GUR5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3869</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000023">
        <property type="protein sequence ID" value="PRC91454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91454">
        <property type="protein sequence ID" value="PRC91454"/>
        <property type="gene ID" value="S2091_3869"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015411837" evidence="1">
        <location>
            <begin position="24"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="83" mass="8902" checksum="02A459A2CFB9A8E5" modified="2018-07-18" version="1">MKLKFISLLFAVLALMITPVTNAQVRIGVGIGVNTCGYPALYQACPYYAPPVGVYVGGGYWGVHRGNGPRGHDRGHSDGRGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GV86</accession>
    <name>A0A2S9GV86_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3736</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000021">
        <property type="protein sequence ID" value="PRC91620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91620">
        <property type="protein sequence ID" value="PRC91620"/>
        <property type="gene ID" value="S2091_3736"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021390">
        <property type="entry name" value="DUF3025"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11227">
        <property type="entry name" value="DUF3025"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="273" mass="30501" checksum="905E9187BCE9376C" modified="2018-07-18" version="1">MESCLSLVFNIDEGVDWCAPWLDSVRAVSGEIVAAQQWRDALNLQAKKLSLRNHAGLPINFTAQQDLPAGVSYEAHIGATGLVPTRDNLHDFFNALVWLAFPRIKVQLNALQAAQIASLGVGKSRGAARDAATLFDENAALLAVTDTLEGRAIVQALRTHQWSQLFVEQRQQFMKHAHVFLFGHAIMEKLVRPYKAITAHTLVCWVSPNFHELSAVEQRAELDQQIAAQLQQQELLPTAFSPLPVLGVPGWWPDQTAEFYADPHVFRPERQRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVD7</accession>
    <name>A0A2S9GVD7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3608</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000020">
        <property type="protein sequence ID" value="PRC91670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91670">
        <property type="protein sequence ID" value="PRC91670"/>
        <property type="gene ID" value="S2091_3608"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="78"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="108"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="146"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="182" mass="21242" checksum="CBAE607C0B95C0E5" modified="2018-07-18" version="1">MKLVNKIKHVCAKKMAQIDGRQLVILFLYVFVLGFFFAKVEIQIEGPDGGWAANLPTWRIEQHWLLTLFWGGRAMTGYHAWVFTFIGLIFHLPIFLIGKWSWRIEARVVASVMLFWVIEDFLWFVLNPAFGLARFDPINVTWHRHWWGGAPIDYWFAIAIGMVMLAYSFSDKTEKPGFEEAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVD8</accession>
    <name>A0A2S9GVD8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Monogalactosyldiacylglycerol (MGDG) synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_3609</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyltransferase 28 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000020">
        <property type="protein sequence ID" value="PRC91671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91671">
        <property type="protein sequence ID" value="PRC91671"/>
        <property type="gene ID" value="S2091_3609"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016758">
        <property type="term" value="F:hexosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009247">
        <property type="term" value="P:glycolipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009695">
        <property type="entry name" value="Diacylglyc_glucosyltr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007235">
        <property type="entry name" value="Glyco_trans_28_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04101">
        <property type="entry name" value="Glyco_tran_28_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06925">
        <property type="entry name" value="MGDG_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="MGDG_synth" evidence="6">
        <location>
            <begin position="17"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_tran_28_C" evidence="5">
        <location>
            <begin position="225"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF06925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC91671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="378" mass="42440" checksum="7D9935F6F9AF8DAF" modified="2018-07-18" version="1">MPQPRVLMISVSAGSGHVRAAEALLETSSQFSQPQFSHIHAQHIDVMSYVSRSFRGVYSDFYRHLINHAPALWAYLYKKTDDAQRSDISSMLRRSIEQLCTKKLIKKIAEFKPDHIICTHFLPAELLAREIKHGRLTCPVWVQVTDFDLHSLWVQPHMRGYFAANHEVAFKMRERGIANDVVHVTGIPVSPVFLADKKKHDCRMELCLKPELTTALILSGGARIGTVTEIAERLLRNNDTLQVIAVAGNNPLRLAELQQLAIQYTDRLVIFGFSKCIENLMAASDVVITKPGGLTSSECLIMGLPMLLVDPIPGQEERNGDYLMEQGAAVKAHDIVGLDFKIRQFIVEPERLVTMRQKMLAIAKPNAAHAVLTHVLER</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVF1</accession>
    <name>A0A2S9GVF1_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 9">2-isopropylmalate synthase</fullName>
            <ecNumber evidence="5 9">2.3.3.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Alpha-IPM synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Alpha-isopropylmalate synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">leuA</name>
        <name evidence="11" type="ORF">S2091_3643</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 9">Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>3-methyl-2-oxobutanoate + acetyl-CoA + H2O = (2S)-2-isopropylmalate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:21524"/>
            <dbReference type="ChEBI" id="CHEBI:1178"/>
            <dbReference type="ChEBI" id="CHEBI:11851"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="EC" id="2.3.3.13"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 9">Amino-acid biosynthesis; L-leucine biosynthesis; L-leucine from 3-methyl-2-oxobutanoate: step 1/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 9">Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.3.13" evidence="5 9"/>
    <dbReference type="EMBL" id="PUGF01000020">
        <property type="protein sequence ID" value="PRC91705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91705">
        <property type="protein sequence ID" value="PRC91705"/>
        <property type="gene ID" value="S2091_3643"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00048">
        <property type="reaction ID" value="UER00070"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003852">
        <property type="term" value="F:2-isopropylmalate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009098">
        <property type="term" value="P:leucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01025">
        <property type="entry name" value="LeuA_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013709">
        <property type="entry name" value="2-isopropylmalate_synth_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002034">
        <property type="entry name" value="AIPM/Hcit_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036230">
        <property type="entry name" value="LeuA_allosteric_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005671">
        <property type="entry name" value="LeuA_bact_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000891">
        <property type="entry name" value="PYR_CT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00682">
        <property type="entry name" value="HMGL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08502">
        <property type="entry name" value="LeuA_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00917">
        <property type="entry name" value="LeuA_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110921">
        <property type="entry name" value="SSF110921"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00973">
        <property type="entry name" value="leuA_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00815">
        <property type="entry name" value="AIPM_HOMOCIT_SYNTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00816">
        <property type="entry name" value="AIPM_HOMOCIT_SYNTH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50991">
        <property type="entry name" value="PYR_CT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="8 9" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="6 9" id="KW-0432">Leucine biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pyruvate carboxyltransferase" evidence="10">
        <location>
            <begin position="5"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC91705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="512" mass="55732" checksum="A3294C3297D823C0" modified="2018-07-18" version="1">MAEKLIIFDTTLRDGEQSPGASMTRDEKIRIAKQLERMRVDVIEAGFAAASQGDFESIQAISSVIKESIVCSLSRANDRDISRAAEALVGAEHKRIHTFIATSALHMEKKLRMSPEQVLEQAKMSVRFARKFTDDVEFSAEDGSRSDIDFLCRVIEVAINEGATTINIPDTVGYGVPEMYGVLLKTLRERVPNSDKAIWSVHCHNDLGMAVANSLAGVMIGGARQVECTINGLGERAGNTALEELVMAVRTRKDYFDFELGIDATLLVPTSKLVSQITGFNVQPNKAVVGANAFAHASGIHQDGILKARDTYEIMRAEDVGWAANKIVLGKLSGRNAFKQRLDELGISLDSEAEVNAAFNRFKELADRKSEIFDEDIMSLVSDEQQSHIQEHYRYVSLAQRSETGEQPYAKVVFSIEGKEAICEGHGNGPVDATLAAIESVTQSGAELLLFSVNAITTGTQSQGEVTMRLSKAGRIVNGVGADPDIVVASAKAYISALNKLHSKVEKVNPQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVH8</accession>
    <name>A0A2S9GVH8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Lipopolysaccharide transport periplasmic protein LptA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_3478</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000019">
        <property type="protein sequence ID" value="PRC91723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91723">
        <property type="protein sequence ID" value="PRC91723"/>
        <property type="gene ID" value="S2091_3478"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001530">
        <property type="term" value="F:lipopolysaccharide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015920">
        <property type="term" value="P:lipopolysaccharide transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014340">
        <property type="entry name" value="LptA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005653">
        <property type="entry name" value="OstA-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03968">
        <property type="entry name" value="LptD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03002">
        <property type="entry name" value="outer_YhbN_LptA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0574">Periplasm</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015593365" evidence="4">
        <location>
            <begin position="23"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="domain" description="OstA-like_N" evidence="5">
        <location>
            <begin position="32"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="183"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="188"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC91723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="211" mass="23063" checksum="940CD21518FA3F89" modified="2018-07-18" version="1">MNKWPFHLVFLTLSLVLIMAHAEKADSQQDLHIRAESQTYDGNKKVTVHIGNVHVTKGTLVIDAARMEVVQDANGGNVGTLFSGPEKLVHYRQKRDGGPDLWVEGEADKAVYDDTLGQIKLYNKAHLILLDGKNKTHESSGIYISYDSRTDFMSMNNTLDGVSVPGAGFTDVVIYPLVKKEADLKSPTSKSGDSSGNKPATKSPPNSTELH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVI3</accession>
    <name>A0A2S9GVI3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional activator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3487</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000019">
        <property type="protein sequence ID" value="PRC91732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91732">
        <property type="protein sequence ID" value="PRC91732"/>
        <property type="gene ID" value="S2091_3487"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025979">
        <property type="entry name" value="ChrR-like_cupin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12973">
        <property type="entry name" value="Cupin_7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cupin_7" evidence="1">
        <location>
            <begin position="19"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="domain" description="Cupin_7" evidence="1">
        <location>
            <begin position="127"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="226" mass="24734" checksum="792C1FA6253F9756" modified="2018-07-18" version="1">MKLNSNFLQRVVVEVSGLNWVDSPVTGIQRQSIERDGEEVARATSIVRYAPGSAFENHKHELGEEILLLDGVFSDESGSFGSGTYIKNPPGSSHTPSSTTGCTLFVKLRHLDLADSHRTVIDSHKATWFPGLVPGLSVLPLSEFGAQHTALVRWAPGTQFNSHRHYGGEEIYVLEGVFEDEFGRYPAGTWMRSPHLSAHRPFSNEGCTILVKTGHLPVAEPSEALA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVJ1</accession>
    <name>A0A2S9GVJ1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative small protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3656</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000020">
        <property type="protein sequence ID" value="PRC91718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91718">
        <property type="protein sequence ID" value="PRC91718"/>
        <property type="gene ID" value="S2091_3656"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007423">
        <property type="entry name" value="Sel_put"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38453">
        <property type="entry name" value="PTHR38453"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04328">
        <property type="entry name" value="Sel_put"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="64" mass="7490" checksum="2799EEA080DAB80F" modified="2018-07-18" version="1">MFEDLGKVGRYLGQAARLMVGVPDYEVYVEHMRVNHPDKHCMTYEEFFRERQEARYGNGAGKCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVN3</accession>
    <name>A0A2S9GVN3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3538</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000019">
        <property type="protein sequence ID" value="PRC91783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91783">
        <property type="protein sequence ID" value="PRC91783"/>
        <property type="gene ID" value="S2091_3538"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="95" mass="10720" checksum="F33C1EF30A396D7E" modified="2018-07-18" version="1">MALNNYHFLCATEPNLSGSLINLQSYLRLRGNIIDCDELDKLDIYKDIDQNAQAPGSSFTVAKALIDNKVGLYQEEYLGVVKEIVLDMHIKLECE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVS0</accession>
    <name>A0A2S9GVS0_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">Flagellar basal-body rod protein FlgG</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6 7">Distal rod protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">S2091_3381</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="5 7">The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Bacterial flagellum basal body</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the flagella basal body rod proteins family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000018">
        <property type="protein sequence ID" value="PRC91825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91825">
        <property type="protein sequence ID" value="PRC91825"/>
        <property type="gene ID" value="S2091_3381"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009426">
        <property type="term" value="C:bacterial-type flagellum basal body, distal rod"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071973">
        <property type="term" value="P:bacterial-type flagellum-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001444">
        <property type="entry name" value="Flag_bb_rod_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019776">
        <property type="entry name" value="Flagellar_basal_body_rod_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020013">
        <property type="entry name" value="Flagellar_FlgE/F/G"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010930">
        <property type="entry name" value="Flg_bb/hook_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037925">
        <property type="entry name" value="FlgE/F/G-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012834">
        <property type="entry name" value="FlgG_G_neg"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00460">
        <property type="entry name" value="Flg_bb_rod"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06429">
        <property type="entry name" value="Flg_bbr_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117143">
        <property type="entry name" value="SSF117143"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03506">
        <property type="entry name" value="FlgEFG_subfam"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02488">
        <property type="entry name" value="flgG_G_neg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00588">
        <property type="entry name" value="FLAGELLA_BB_ROD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0975">Bacterial flagellum</keyword>
    <keyword evidence="10" id="KW-0966">Cell projection</keyword>
    <keyword evidence="10" id="KW-0969">Cilium</keyword>
    <keyword evidence="10" id="KW-0282">Flagellum</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flg_bb_rod" evidence="8">
        <location>
            <begin position="8"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="domain" description="Flg_bbr_C" evidence="9">
        <location>
            <begin position="182"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00025933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00032912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF06429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC91825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="263" mass="27883" checksum="2024517E3F8CBA23" modified="2018-07-18" version="1">MIRSLWIAKTGMDAQQTSMDVIANNLANVSTTGFKGTRVIFEDLLYQTIRQPGAQSTQQTQLPSGLQVGLGVRPIATERIFTQGNPQMTGNAQDVAINGNGFFQVLMPDGSTAYTRDGSFQLDNQGQLVTASGYPIQPALTIPATATSLTIGSDGVVTITQPNSQLPVQIGALQLATFVNPAGLDSIGENLYLETGSSGNANTTVPGLNGSGTLMQNYVEGSNVNVATELVNMIQTQRSYEMNSQAITTSNQMLQRLVTMAQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVU6</accession>
    <name>A0A2S9GVU6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3398</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000018">
        <property type="protein sequence ID" value="PRC91842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91842">
        <property type="protein sequence ID" value="PRC91842"/>
        <property type="gene ID" value="S2091_3398"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="112" mass="11990" checksum="F87AD95CBCEBDE53" modified="2018-07-18" version="1">MIYYIAYFFGGAFLANSIPHLTNGMSGRPFPTPFATPPGQGESSSTLDVIWGALNIIIGYCLLFQISDFNVRSLLDLSAAGSGSLAIALYLSRRFGNVYGGIKTGTRKVNDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVX6</accession>
    <name>A0A2S9GVX6_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptide chain release factor 2</fullName>
            <shortName evidence="4">RF-2</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">prfB</name>
        <name evidence="6" type="ORF">S2091_3429</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="4">Methylated by PrmC. Methylation increases the termination efficiency of RF2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the prokaryotic/mitochondrial release factor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000018">
        <property type="protein sequence ID" value="PRC91873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91873">
        <property type="protein sequence ID" value="PRC91873"/>
        <property type="gene ID" value="S2091_3429"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016149">
        <property type="term" value="F:translation release factor activity, codon specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00094">
        <property type="entry name" value="Rel_fac_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005139">
        <property type="entry name" value="PCRF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000352">
        <property type="entry name" value="Pep_chain_release_fac_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045853">
        <property type="entry name" value="Pep_chain_release_fac_I_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004374">
        <property type="entry name" value="PrfB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03462">
        <property type="entry name" value="PCRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00472">
        <property type="entry name" value="RF-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00937">
        <property type="entry name" value="PCRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75620">
        <property type="entry name" value="SSF75620"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00020">
        <property type="entry name" value="prfB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00745">
        <property type="entry name" value="RF_PROK_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4" id="KW-0488">Methylation</keyword>
    <keyword evidence="3 4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RF_PROK_I" evidence="5">
        <location>
            <begin position="229"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="modified residue" description="N5-methylglutamine" evidence="4">
        <location>
            <position position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS00745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC91873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="349" mass="39372" checksum="C8CAC4F5DEABFBAA" modified="2018-07-18" version="1">MKLNFGGIFDYDVKSEKLEQVNAEMEDPAIWNDPKKAQDLGREKKSLEAIVHTLTKIDADLRDAVDLFTMAREEQDEDTMEAIEGDADVLRLLVEGMEFRRMFNNPMDPNNCFIDIQSGAGGTEAQDWASMILRQYLRYCERKGFKVEILEQSDGEVAGIKTATLKVEGDYAYGFLRTETGVHRLVRKSPFDSANGRHTSFCSLFVYPEVDDSIDIDVNPADVRVDTYRASGAGGQHINKTDSAVRLTHGPSGIVVQCQNDRSQHRNRAEAWDMLKAKLYELELRNRMSEQQKLEDSKTDVGWGHQIRSYVLDQSRIKDLRTSFETGNTKAVLDGDLDGFIAASLKQGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GW37</accession>
    <name>A0A2S9GW37_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DnaJ domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3274</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000017">
        <property type="protein sequence ID" value="PRC91932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91932">
        <property type="protein sequence ID" value="PRC91932"/>
        <property type="gene ID" value="S2091_3274"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002939">
        <property type="entry name" value="DnaJ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008971">
        <property type="entry name" value="HSP40/DnaJ_pept-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01556">
        <property type="entry name" value="DnaJ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="SSF46565"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49493">
        <property type="entry name" value="SSF49493"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="2">
        <location>
            <begin position="5"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="319" mass="34949" checksum="0070BC6770E3CE42" modified="2018-07-18" version="1">MKYKDYYQILGVERSASTDDIKKAYRKLAHKYHPDVSKDPEGEEKFKEIAEAYATLKNTEKREEYDAMGPRTAGDNFTPPPEWQNRYGTTGSNFDDVDISDLLNAFRSSGFADVKNHGRASHAMPGENYTVTVPISLEKIATGGETDVRVEVPEQDENGLPHRVSRTFRVNIPKAASDGQRLRLVGKGGPGRNGGKPGDLYVALTIAPHAIFRVSGRDLFFDLLLTPSEAVLGTTVEIPTLNGRLELTIKPGTSSGQRLRLAKRGLPSAHGDAGDLYAVSRIVVPKQASDQEKALYRQLAAISGGTVHSVRESLEKEAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GW73</accession>
    <name>A0A2S9GW73_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">V4R domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3317</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000017">
        <property type="protein sequence ID" value="PRC91975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91975">
        <property type="protein sequence ID" value="PRC91975"/>
        <property type="gene ID" value="S2091_3317"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045987">
        <property type="entry name" value="DUF5943"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024096">
        <property type="entry name" value="NO_sig/Golgi_transp_ligand-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004096">
        <property type="entry name" value="V4R"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19367">
        <property type="entry name" value="DUF5943"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02830">
        <property type="entry name" value="V4R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00989">
        <property type="entry name" value="V4R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111126">
        <property type="entry name" value="SSF111126"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="V4R" evidence="1">
        <location>
            <begin position="104"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="172" mass="19339" checksum="2A742CE97F26DE18" modified="2018-07-18" version="1">MKPQLPIEVNEETGVWSTDGLPMLYVPRHFFVNNHVAIEAALGRERYAQQLYGAGYKSAYFWCEKEAATHDMSGLAVFEHYLKRLSQRGWGLFVFDSVNVETGHARISLHHSSFVLAQPDAHDKLCYMFAGWFSGAMDWVAQTTGRSYATTSSETQCAAEGHAHCVFTVEPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GW91</accession>
    <name>A0A2S9GW91_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CENP-V/GFA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_3324</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Gfa family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000017">
        <property type="protein sequence ID" value="PRC91982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91982">
        <property type="protein sequence ID" value="PRC91982"/>
        <property type="gene ID" value="S2091_3324"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016846">
        <property type="term" value="F:carbon-sulfur lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006913">
        <property type="entry name" value="CENP-V/GFA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011057">
        <property type="entry name" value="Mss4-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04828">
        <property type="entry name" value="GFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51316">
        <property type="entry name" value="SSF51316"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51891">
        <property type="entry name" value="CENP_V_GFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CENP-V/GFA" evidence="3">
        <location>
            <begin position="5"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC91982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="136" mass="14775" checksum="8DDE1367480D6FE6" modified="2018-07-18" version="1">MSNLSTGSCLCGAVHFEYSGEPVFSGNCHCRDCQRSSGSAFTPALFVPEENVSISGAVKYYESKADSGNAISRGFCPNCGSQLFARLEIMPKMLGLRAGTLDDPSNFHPKVNFFTSSASHWDHMNPDLPTYPKSPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWD4</accession>
    <name>A0A2S9GWD4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Type II secretory pathway ATPase PulE/Tfp pilus assembly pathway</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3167</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GSP E family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000016">
        <property type="protein sequence ID" value="PRC92032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92032">
        <property type="protein sequence ID" value="PRC92032"/>
        <property type="gene ID" value="S2091_3167"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001482">
        <property type="entry name" value="T2SS/T4SS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037257">
        <property type="entry name" value="T2SS_E_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007831">
        <property type="entry name" value="T2SS_GspE_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00437">
        <property type="entry name" value="T2SSE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05157">
        <property type="entry name" value="T2SSE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160246">
        <property type="entry name" value="SSF160246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00662">
        <property type="entry name" value="T2SP_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="T2SP_E" evidence="2">
        <location>
            <begin position="404"/>
            <end position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS00662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="589" mass="66057" checksum="ED400EC684F1125C" modified="2018-07-18" version="1">MTKHLDLQHILNWLIHDGILTKETARAQYPLAQAILKNAPMSMHPLTALAQCKLTAITSPGTHLNLDWLTEWLAKRVKLPFYRIDPLKVDFTKVADVMSAVYAARFNILPVEITATSVTIATCEPGNTEWHDEIAKVTRRELKLVLANPLEISQYIAQFFALAKSIKNASKTKGQDVALRNNFEQLVELGNSNKQLDSNDQHIVNIVDWLWQYAFEQRASDIHLEPKRSMAAIRFRIDGVLHQVYQVPVTVMIAMTARIKLLGRMDVIEKRRPQDGRIKTRTNAGQEIELRLSTLPTAFGEKMVMRIFDPEVVVKTLPELGFPTEDALRWKQLTEKPHGIILVTGPTGSGKTTTLYTTLKALATSEVNVCSVEDPIEMVEPSFNQMQVQHGIDLSFADGVRALMRQDPDIIMVGEIRDLATAEMAIQAALTGHLVFSTLHTNDAPSAVMRLLELGVPYYLLEATLVGILAQRLVRTLCPVCKTQDADLPEPIWMTLSEHWNIPKPDKIYRPVGCPECRQTGYRGRTGLYELITVSQAFTKLIRPETDLNALRVQSIKDGMKPLRIAGAYKIIEGLTSCDEVLKVTSTLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWH6</accession>
    <name>A0A2S9GWH6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Mechanosensitive ion channel</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_3208</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MscS (TC 1.A.23) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000016">
        <property type="protein sequence ID" value="PRC92073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92073">
        <property type="protein sequence ID" value="PRC92073"/>
        <property type="gene ID" value="S2091_3208"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006685">
        <property type="entry name" value="MscS_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011066">
        <property type="entry name" value="MscS_channel_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011014">
        <property type="entry name" value="MscS_channel_TM-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023408">
        <property type="entry name" value="MscS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00924">
        <property type="entry name" value="MS_channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="SSF50182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82689">
        <property type="entry name" value="SSF82689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82861">
        <property type="entry name" value="SSF82861"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="59"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="86"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="125"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="170"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="212"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC92073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="437" mass="48443" checksum="A0C4DAA1852AC874" modified="2018-07-18" version="1">MLINLLSDFWTDLHETRVWWQIAVVTLCVLASYFISRLLRKRFPIDVSYSPAETLAAQAFSRILFPAILWGFLYLGKLVLLKWQHVYLLSLLIPIFGSLALIRFGNYLSRRIFARSTNIGNVHLLIEKIFSWGVWIVAILYYTGSLQDVLNFMDATTISVGRNKLSFMEILQAVISVVVTVLLALWASAALDKQLMKVNSIHTSSRLVLSRLGRSLLIVFAILISLSLVGIDLTVLSVFGGALGVGLGLGLQRIASNYVSGFIILLDRSLAIDDLITVDKYTGKVSKINTRYTVLKGLDGVESVIPNEMLVSSPVQNFSLTDRAVWMSTDLTVAYNTDIEALLPMLVAAASSVERVSKTASPSANLINFGLNGLELRIGFWINDPENGKMGVSSQVNRAIWKLLQEQKVEVPYPQTEIRVLDRGQSSPGNTCAEELN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWH9</accession>
    <name>A0A2S9GWH9_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">4-hydroxy-3-methylbut-2-enyl diphosphate reductase</fullName>
            <shortName evidence="5">HMBPP reductase</shortName>
            <ecNumber evidence="5">1.17.7.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ispH</name>
        <name evidence="6" type="ORF">S2091_3214</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>H2O + isopentenyl diphosphate + 2 oxidized [2Fe-2S]-[ferredoxin] = (2E)-4-hydroxy-3-methylbut-2-enyl diphosphate + 2 H(+) + 2 reduced [2Fe-2S]-[ferredoxin]</text>
            <dbReference type="Rhea" id="RHEA:24488"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:128753"/>
            <dbReference type="ChEBI" id="CHEBI:128769"/>
            <dbReference type="EC" id="1.17.7.4"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>dimethylallyl diphosphate + H2O + 2 oxidized [2Fe-2S]-[ferredoxin] = (2E)-4-hydroxy-3-methylbut-2-enyl diphosphate + 2 H(+) + 2 reduced [2Fe-2S]-[ferredoxin]</text>
            <dbReference type="Rhea" id="RHEA:24825"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:57623"/>
            <dbReference type="ChEBI" id="CHEBI:128753"/>
            <dbReference type="EC" id="1.17.7.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="5">Binds 1 [4Fe-4S] cluster per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Isoprenoid biosynthesis; dimethylallyl diphosphate biosynthesis; dimethylallyl diphosphate from (2E)-4-hydroxy-3-methylbutenyl diphosphate: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via DXP pathway; isopentenyl diphosphate from 1-deoxy-D-xylulose 5-phosphate: step 6/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the IspH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.17.7.4" evidence="5"/>
    <dbReference type="EMBL" id="PUGF01000016">
        <property type="protein sequence ID" value="PRC92079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92079">
        <property type="protein sequence ID" value="PRC92079"/>
        <property type="gene ID" value="S2091_3214"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00056">
        <property type="reaction ID" value="UER00097"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00059">
        <property type="reaction ID" value="UER00105"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051745">
        <property type="term" value="F:4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050992">
        <property type="term" value="P:dimethylallyl diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019288">
        <property type="term" value="P:isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016114">
        <property type="term" value="P:terpenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd13944">
        <property type="entry name" value="lytB_ispH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00191">
        <property type="entry name" value="IspH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003451">
        <property type="entry name" value="LytB/IspH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30426">
        <property type="entry name" value="PTHR30426"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02401">
        <property type="entry name" value="LYTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00216">
        <property type="entry name" value="ispH_lytB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="3 5" id="KW-0408">Iron</keyword>
    <keyword evidence="4 5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5" id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="224"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="5">
        <location>
            <position position="128"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="14"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="43"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="76"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="98"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="126"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="166"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="196"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="268"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC92079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="307" mass="33348" checksum="4CF89044012E2C12" modified="2018-07-18" version="1">MDKEILLAQPRGFCAGVDRAIEIVERALTQFGAPIYVRHEIVHNAYVVNDLRQKGAVFIEELSDVPSGNTVIFSAHGVSLDVRKEAEQRGLKIFDATCPLVTKVHVEVTKMRREGREIIMIGHQGHPEVEGTMGQADEGMYLVETLQDVAALTVTSPDMLAYVSQTTLSVDDTAEIIAALKQKFPLITEPKKTDICYATTNRQEAVKFMAPQVDAVIVVGSPNSSNSNRLREVAEKKGAAAYMVDNAKQIDPNWLINCTRIGVTAGASAPEVLVQEVIDALKALGAKSVRVLDGVQESVAFPLPKGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWW8</accession>
    <name>A0A2S9GWW8_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">UDP-3-O-acylglucosamine N-acyltransferase</fullName>
            <ecNumber evidence="5">2.3.1.191</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">lpxD</name>
        <name evidence="7" type="ORF">S2091_3072</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a (3R)-hydroxyacyl-[ACP] + a UDP-3-O-[(3R)-3-hydroxyacyl]-alpha-D-glucosamine = a UDP-2-N,3-O-bis[(3R)-3-hydroxyacyl]-alpha-D-glucosamine + H(+) + holo-[ACP]</text>
            <dbReference type="Rhea" id="RHEA:53836"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="Rhea" id="RHEA-COMP:9945"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78827"/>
            <dbReference type="ChEBI" id="CHEBI:137740"/>
            <dbReference type="ChEBI" id="CHEBI:137748"/>
            <dbReference type="EC" id="2.3.1.191"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5">Bacterial outer membrane biogenesis; LPS lipid A biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homotrimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the transferase hexapeptide repeat family. LpxD subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.191" evidence="5"/>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92156">
        <property type="protein sequence ID" value="PRC92156"/>
        <property type="gene ID" value="S2091_3072"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00973"/>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016410">
        <property type="term" value="F:N-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009245">
        <property type="term" value="P:lipid A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03352">
        <property type="entry name" value="LbH_LpxD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00523">
        <property type="entry name" value="LpxD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007691">
        <property type="entry name" value="LpxD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020573">
        <property type="entry name" value="UDP_GlcNAc_AcTrfase_non-rep"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43378">
        <property type="entry name" value="PTHR43378"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04613">
        <property type="entry name" value="LpxD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01853">
        <property type="entry name" value="lipid_A_lpxD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2 5" id="KW-0441">Lipid A biosynthesis</keyword>
    <keyword evidence="1 5" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="4 5" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 5 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="LpxD" evidence="6">
        <location>
            <begin position="22"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00523"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC92156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="356" mass="37490" checksum="0412498F45D744A5" modified="2018-07-18" version="1">MSGLHLSELIDRLGGQLICDTDLVVDSIAPLEHAHANSITFLSNPKLRNQAGNTLAAAIIIKAADAEFLRSQFKGALILVDNPYAYFAKTAQLFAELKRQPLVPGIHPSASVDPTARIAASAAIGPLVCIEENAVIGEHVQIDAGCFIGHGAQIGAHSHFHANVTWHHECRIGQRAIIYSGAVIGGEGFGFANEAGRWLKIPQTGGVAIGDDVEIGANTCIDRGALTDTIIEDGVKLDNQIQIGHNCHIGAHTAMAGCVGVAGSAKIGSHCTFGGAAMVLGHLTIADNVHISSGSMVSRSILEAGQYTGFYPLAKNADWEKSAAIVRNLDSLRDKVRAMEKTIQSLTSAQNGKKDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GX77</accession>
    <name>A0A2S9GX77_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Nicotinate phosphoribosyltransferase (NAPRTase) family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_2970</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NAPRTase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92311">
        <property type="protein sequence ID" value="PRC92311"/>
        <property type="gene ID" value="S2091_2970"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004514">
        <property type="term" value="F:nicotinate-nucleotide diphosphorylase (carboxylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009435">
        <property type="term" value="P:NAD biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01569">
        <property type="entry name" value="PBEF_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041529">
        <property type="entry name" value="DUF5598"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041525">
        <property type="entry name" value="N/Namide_PRibTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016471">
        <property type="entry name" value="Nicotinamide_PRibTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036068">
        <property type="entry name" value="Nicotinate_pribotase-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43816">
        <property type="entry name" value="PTHR43816"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18127">
        <property type="entry name" value="NAMPT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04095">
        <property type="entry name" value="NAPRTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005943">
        <property type="entry name" value="NMPRT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51690">
        <property type="entry name" value="SSF51690"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NAMPT_N" evidence="3">
        <location>
            <begin position="8"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="domain" description="NAPRTase" evidence="2">
        <location>
            <begin position="182"/>
            <end position="451"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF18127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC92311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="489" mass="54584" checksum="745D2268A692D363" modified="2018-07-18" version="1">MNLNPATAIDGYKVDHRRQYPDNTQVVFSNLTARTTRREYTSYLVFFGLQYFIKSFLIKNWEEDFFKQPKDEVIRRFSRRINNYLGPNNVGTQHIADLHDLGYLPIKIMALPEGSVYPLRVPCLVIFNTDERFFWLTNYLETILSTNVWGMCTSATTAHEYKKLLTAYALETDGSTDFVNWQGHDFSFRGMFGAEAAAMSGAAHLLSFTGTDTIPAIDFLEDYYGANSDLELVGGSVAATEHSVMCAGGMDNELETFRRLIQDIYPAGIVSIVSDSWDFWQVMTDFTVKLKEQIVARDGKVVFRPDTGCPVKMICGDADAEIGTPEYKGAIECLWEVFGGSETKQGYKILDPHVGLIYGDSITIERATAICAGLKAKGFASTNVVFGIGSYTYQHVTRDTDGFAVKATFAKISGENREIFKAPKTGDGTKNSAKGLVAVYKDDQGEFYLKDQVSWNNVNECEFVPVFENGKLLNEVTLAEVRARLAATI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GX88</accession>
    <name>A0A2S9GX88_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ATP dependent DNA ligase domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2980</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92321">
        <property type="protein sequence ID" value="PRC92321"/>
        <property type="gene ID" value="S2091_2980"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029319">
        <property type="entry name" value="DNA_ligase_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14743">
        <property type="entry name" value="DNA_ligase_OB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015729306" evidence="1">
        <location>
            <begin position="31"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="domain" description="DNA_ligase_OB_2" evidence="2">
        <location>
            <begin position="224"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="292" mass="32252" checksum="E7F67C1FF983F38C" modified="2018-07-18" version="1">MTLPALRRLTSLLVLCGALAPITLLSAANASEVNLSKPAILLAQNYHPSINLADYLVSEKLDGVRAIWDGKALRFRSGQVINAPAWFVAKLPAHALDGELWMGRRSFDRVSAATRRLVPLDAEWKAITYQVVELPGGAGTFSERLLMLKSSVAKMNAPWLQVPAQFTVVDDAALQLKLQKIVRAGGEGLMLHRADAVWQTGRSEVLLKLKMQLDAEAKVIAYLPGKGKYLGMMGALEVEMPDGKRFRLGTGFSDAQRRTPPEIGSMVTYRYRDLTPQGLPRFANFLRIREIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXG0</accession>
    <name>A0A2S9GXG0_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 4">N5-carboxyaminoimidazole ribonucleotide mutase</fullName>
            <shortName evidence="3 4">N5-CAIR mutase</shortName>
            <ecNumber evidence="3 4">5.4.99.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">5-(carboxyamino)imidazole ribonucleotide mutase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">purE</name>
        <name evidence="7" type="ORF">S2091_2780</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 4">Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3 4">
            <text>5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole + H(+) = 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate</text>
            <dbReference type="Rhea" id="RHEA:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58730"/>
            <dbReference type="ChEBI" id="CHEBI:77657"/>
            <dbReference type="EC" id="5.4.99.18"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 4">Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate from 5-amino-1-(5-phospho-D-ribosyl)imidazole (N5-CAIR route): step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the AIR carboxylase family. Class I subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.18" evidence="3 4"/>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92405">
        <property type="protein sequence ID" value="PRC92405"/>
        <property type="gene ID" value="S2091_2780"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00943"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034023">
        <property type="term" value="F:5-(carboxyamino)imidazole ribonucleotide mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01929">
        <property type="entry name" value="PurE_classI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033747">
        <property type="entry name" value="PurE_ClassI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000031">
        <property type="entry name" value="PurE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024694">
        <property type="entry name" value="PurE_prokaryotes"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00731">
        <property type="entry name" value="AIRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001338">
        <property type="entry name" value="AIR_carboxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01001">
        <property type="entry name" value="AIRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01162">
        <property type="entry name" value="purE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="1 3 4" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AIRC" evidence="6">
        <location>
            <begin position="2"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3 5">
        <location>
            <position position="10"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3 5">
        <location>
            <position position="13"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3 5">
        <location>
            <position position="40"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR001338"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR001338-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC92405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="162" mass="16853" checksum="E3D484FEF935E930" modified="2018-07-18" version="1">MATVGIVMGSTSDWDVMKEAAQICKDFGISYSARALSAHRTPVELEQWMEEMEASGCQAFIAGAGAAAHLAGVVAAKTILPTFGVPIPSKYLKGLDSLLAMVQMPKGIPVSTLAIGEAGAANAGLSVVAILALHDADMKAKLINFRATQAEKVRNSVLPELA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXH1</accession>
    <name>A0A2S9GXH1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2797</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92422">
        <property type="protein sequence ID" value="PRC92422"/>
        <property type="gene ID" value="S2091_2797"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="444" mass="48265" checksum="5A037A5502A7BDAA" modified="2018-07-18" version="1">MQNSTEHIDSHEPEDTSSSLQAYFKPEISFDDIEQVYQLKRAQPLLQAFTALFHGGFDSVLVRLLVLRELASDAQSSSFSRADINAKLAYLQADSLDTVLARLRSHQLLIWEAATSVYRVAPMARNVLSALDSLLSTQQSAEQGEDPADMGFLLTQVAGAQALGGVTVEQLQHLLGRLVDLTEEFRDAIASGSEYRLRASQSKWNNACDWVEKGTKIIYAITTDGNADAATQRAAQAIGRAQSALLNMQGMFSRALNQIERQRVHLGQSGLSTTDIKSWLMAQDDLAALADGAIDMPVTPLFATPAEMIDVAEAELFAERNQQSSELPSGTDTQFQVQDDAVLYTQLDAWLSSLNQLSVPSNSELPTGVDVQQILLPNSFAIASYRASLLPLIGDQDAGTSQGAAARLSSLPMQFVLTDKLIPIKDSEVAGLSDAQLIFQTQDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXL3</accession>
    <name>A0A2S9GXL3_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 11">Alkyl hydroperoxide reductase C</fullName>
            <ecNumber evidence="4 11">1.11.1.26</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8 11">Peroxiredoxin</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9 11">Thioredoxin peroxidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">S2091_2840</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>a hydroperoxide + H(+) + NADH = an alcohol + H2O + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:62628"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30879"/>
            <dbReference type="ChEBI" id="CHEBI:35924"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.11.1.26"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="11">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.26" evidence="4 11"/>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92465">
        <property type="protein sequence ID" value="PRC92465"/>
        <property type="gene ID" value="S2091_2840"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102039">
        <property type="term" value="F:alkylhydroperoxide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051920">
        <property type="term" value="F:peroxiredoxin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017559">
        <property type="entry name" value="AhpC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000866">
        <property type="entry name" value="AhpC/TSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024706">
        <property type="entry name" value="Peroxiredoxin_AhpC-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019479">
        <property type="entry name" value="Peroxiredoxin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10681:SF121">
        <property type="entry name" value="PTHR10681:SF121"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10417">
        <property type="entry name" value="1-cysPrx_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
        <property type="entry name" value="AhpC-TSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000239">
        <property type="entry name" value="AHPC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03137">
        <property type="entry name" value="AhpC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0049">Antioxidant</keyword>
    <keyword evidence="11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6 11" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="11" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="12">
        <location>
            <begin position="2"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="active site" description="Cysteine sulfenic acid (-SOH) intermediate" evidence="10">
        <location>
            <position position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000318"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00032077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00032824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000239-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU366004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PRC92465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="187" mass="20869" checksum="9AF2FDAD453FFB4D" modified="2018-07-18" version="1">MSLINTEIKPFNATAYHNGKFVPVSNETLKGKWSVFVFYPADFTFVCPTELGDLADHYAEFQKLGVEIYSVSTDTHFAHKAWHDTSDTIRKINYPMVADPTLALSRNFEVLIEEEGLALRGTFVVNPEGHIKVMEVHDNGIGRDAKELLRKVQAAQYVASHPNEVCPAKWTPGAHTLTPSLDLIGKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXY9</accession>
    <name>A0A2S9GXY9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2901</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92526">
        <property type="protein sequence ID" value="PRC92526"/>
        <property type="gene ID" value="S2091_2901"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="36"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="68"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="90" mass="10294" checksum="2923F8F3B9091E46" modified="2018-07-18" version="1">MSSQLPKPFEKPWFIVNCVALCIGIYAMIFHHATVIFGISMISFAAHAIYSGHFSLRNTDYSRREDSGAFWMSVFAYTCIGLFFCLIRKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GY28</accession>
    <name>A0A2S9GY28_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2674</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92619">
        <property type="protein sequence ID" value="PRC92619"/>
        <property type="gene ID" value="S2091_2674"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="71" mass="7718" checksum="A634BB8B461E2BD4" modified="2018-07-18" version="1">MRTTCEKGVIHADVVNESDDVEYIRADKVKELQLAAAKAALEAAANGMPWICHQDQIKAINPQAILDSLGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GY54</accession>
    <name>A0A2S9GY54_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2710</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92655">
        <property type="protein sequence ID" value="PRC92655"/>
        <property type="gene ID" value="S2091_2710"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="126"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="142"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="162"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="187"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="334" mass="37125" checksum="45BE58C73F2AE6C4" modified="2018-07-18" version="1">MSEMQNNNPAPYPPDTKAKGWRFELDLEQISQSDTWALASLEIRPWLLMLWSVSWQQTPCGSLTGDDEIIAARIGMKLTAFKKCRSVLLRGWVSANDGRLYHPVVTQRVLSMIDVKNKEKDRKAAYRAKMSGIVPRDNQGTDAGQDARRDADGRGSDPGEDATGTGTGTGTSFKSNKDSSSSNDLPENQKFDDEFHGKAPMPKPEEPAPDTSEATKFAVALRKQGVKVTAVHPTLQIWVDRGVTMLQANEAIQKARQYKPHPEQIEMNYLNTILCEALKPKAAKSAPMPEVQKWHESAAGIQAKAKEFGLTQESGEHFPYFRDRVAKAVREART</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GY60</accession>
    <name>A0A2S9GY60_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF4055 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2720</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92665">
        <property type="protein sequence ID" value="PRC92665"/>
        <property type="gene ID" value="S2091_2720"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025129">
        <property type="entry name" value="DUF4055"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13264">
        <property type="entry name" value="DUF4055"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4055" evidence="1">
        <location>
            <begin position="248"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="479" mass="52183" checksum="CBA1112FBB00E829" modified="2018-07-18" version="1">MLKVNEPSDAITAMQPDWAKVDALVGGTKAMRAAGKAYLPQWPSEKDASYEYRLKTSTLFNAFSHTVENMAGKPFSEPIAFDKVDETIQTWFDNIDLAGRNLHVFANEVLKSGLKYGLTHILVDYQRTEGVQTLADEKAMGARPYVIHIPPGAILGWMSDVVHGVEMLTQVRILENVTVPDGSFGTKLIQQVRVLEVGKWATFRKGTDGEWAKFDSGAVMQKAGVPLNFIPLVTYYGKRTGFMTADLPLGDLADLNIKHWQSTSDQDSILHTARVPILAVFGDDRDEDNSKPVVIGAGSIFNLPLGADAKFVEHTGAAIGAGRQSLQDLEAQMRLIGAELLIDATGDVSATQAALDTAQQQSKLSAMVQNLEDTLDQVTDIMSAWAGITNDGDITIFKDFAKASVTGQTEIMLTNATTLNLISPETWFSEMKRRGVIDPDALWADEQERLSLHAPMLPNIPPAVVPPVPAVIPPENVEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GY88</accession>
    <name>A0A2S9GY88_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2739</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92684">
        <property type="protein sequence ID" value="PRC92684"/>
        <property type="gene ID" value="S2091_2739"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="275" mass="29021" checksum="5062D613F02BA597" modified="2018-07-18" version="1">MTAMRVLSSNLADSSTTTASTTAGAYVAANLALDTKSLVWRATGLSATLSCVWGSTQNINCVILPFNNFTPAATIRVQGYSDSAGTILVVDTGTIPANPAPATILNGFTLLASQSAYAYGGGSYAMAYFALTGVQKIVVTLNDSANTAGYLEVSRLLAGAYWSPAYNADMGASLTLQDTSKNVRSEGGDLITALGTFNRKLGFTLSKMSPADRAALTIIFRSNGFRSPMFISMFPQNTDSQLEDDHQIYGKLTAMSAMTIPVYSAYSAPLEIEEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYA2</accession>
    <name>A0A2S9GYA2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Prepilin-type N-terminal cleavage/methylation domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2748</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92693">
        <property type="protein sequence ID" value="PRC92693"/>
        <property type="gene ID" value="S2091_2748"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015627">
        <property type="term" value="C:type II protein secretion system complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015628">
        <property type="term" value="P:protein secretion by the type II secretion system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000983">
        <property type="entry name" value="Bac_GSPG_pilin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00813">
        <property type="entry name" value="BCTERIALGSPG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="127" mass="14105" checksum="DAFD429AA6046297" modified="2018-07-18" version="1">MYAKNRQRGFTLIELLVVLAIIALLLTLAVPRYFQTIDASKETILISNLQATRDAIDKFYGDTGKYPDTLADLVNKKYLRSLPMDPITQSTATWILIAPDDQEKGNVYNIKSGAPGQTHLGQSFSSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYE9</accession>
    <name>A0A2S9GYE9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Sugar (And other) transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_2482</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92752">
        <property type="protein sequence ID" value="PRC92752"/>
        <property type="gene ID" value="S2091_2482"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="43"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="67"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="99"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="125"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="166"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="205"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="255"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="294"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="320"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="351"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="387"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="415"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="28"/>
            <end position="438"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC92752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="438" mass="47039" checksum="5AB5D02A2879EFDE" modified="2018-07-18" version="1">MSGIISNNAAINNKSQHEAHSDITPSEIAIGVIIGRASEYFDFFVYALASVLVFPSVFFPFEAKLEGALYAFVIFSFAFIARPFGTIIFMAIQQRFGRVAKLTIALFLLGISTAGIAFLPTYADLGAHAIVLLALFRIGQGIAIGGSWDGLPSLLALNAPAHRRGWYAMLGQLGAPVGFMLAGSLFAYLVSTLSNQDFLEWGWRYPFYVAFAINVVAVFARIQLVSSDAFTRLLEQRELEPANVIEMGRSQRRNILIGALAALASYALFHLVTVFPLSWISLYSTRSISDVLEVQVIGAGFMVIGIVASGIISDRFGRRTTLAAFAMLIAILSGFVPTLMDGSEFQQNAFILLGFGLLGLSYGQAAGAVTANFALKYRYTGAALTSDISWLVGAGFAPLVALGLAAHFGLAYVSLYLLSGAVCTLAALSLNRALEVRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYM1</accession>
    <name>A0A2S9GYM1_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ribosomal RNA large subunit methyltransferase H</fullName>
            <ecNumber evidence="4">2.1.1.177</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">23S rRNA (pseudouridine1915-N3)-methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">23S rRNA m3Psi1915 methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">rRNA (pseudouridine-N3-)-methyltransferase RlmH</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rlmH</name>
        <name evidence="5" type="ORF">S2091_2549</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>pseudouridine(1915) in 23S rRNA + S-adenosyl-L-methionine = H(+) + N(3)-methylpseudouridine(1915) in 23S rRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42752"/>
            <dbReference type="Rhea" id="RHEA-COMP:10221"/>
            <dbReference type="Rhea" id="RHEA-COMP:10222"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:74486"/>
            <dbReference type="EC" id="2.1.1.177"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the RNA methyltransferase RlmH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.177" evidence="4"/>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92819">
        <property type="protein sequence ID" value="PRC92819"/>
        <property type="gene ID" value="S2091_2549"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070038">
        <property type="term" value="F:rRNA (pseudouridine-N3-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd18081">
        <property type="entry name" value="RlmH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00658">
        <property type="entry name" value="23SrRNA_methyltr_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003742">
        <property type="entry name" value="RlmH-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33603">
        <property type="entry name" value="PTHR33603"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02590">
        <property type="entry name" value="SPOUT_MTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004505">
        <property type="entry name" value="MT_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="SSF75217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 4" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="4">
        <location>
            <begin position="123"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="73"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="104"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC92819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="156" mass="17611" checksum="E9D7DD8CA12F20EE" modified="2018-07-18" version="1">MQLIIAAVGHKMPTWIESGFREYSKRMPAECRIVLKEIKPVERSGSKTAQTVMALERAKIEAVIPKQTRIVALDEHGKDLTTMQLSQLLTEWQQEGGDTCFVIGGADGLDAEFKVRATLKIRISSLTLPHGMVRVILAEQLYRAWSITQNHPYHRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYN9</accession>
    <name>A0A2S9GYN9_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">2-aminoethylphosphonate--pyruvate transaminase</fullName>
            <ecNumber evidence="4">2.6.1.37</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">2-aminoethylphosphonate aminotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">AEP transaminase</fullName>
            <shortName evidence="4">AEPT</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">phnW</name>
        <name evidence="7" type="ORF">S2091_2506</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Involved in phosphonate degradation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>(2-aminoethyl)phosphonate + pyruvate = L-alanine + phosphonoacetaldehyde</text>
            <dbReference type="Rhea" id="RHEA:17021"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:57418"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="ChEBI" id="CHEBI:58383"/>
            <dbReference type="EC" id="2.6.1.37"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 4 5">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.37" evidence="4"/>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92776">
        <property type="protein sequence ID" value="PRC92776"/>
        <property type="gene ID" value="S2091_2506"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047304">
        <property type="term" value="F:2-aminoethylphosphonate-pyruvate transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019700">
        <property type="term" value="P:organic phosphonate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01376">
        <property type="entry name" value="PhnW_aminotrans_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012703">
        <property type="entry name" value="NH2EtPonate_pyrv_transaminase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024169">
        <property type="entry name" value="SP_NH2Trfase/AEP_transaminase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000524">
        <property type="entry name" value="SPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03301">
        <property type="entry name" value="PhnW-AepZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02326">
        <property type="entry name" value="transamin_PhnW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="2 4 5" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="3 4 7" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_5" evidence="6">
        <location>
            <begin position="30"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="4 5">
        <location>
            <position position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000524-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC92776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="369" mass="39552" checksum="F2D16319EA802626" modified="2018-07-18" version="1">MRDPLLLTPGPLTTSLATKTAMLHDWGSWDKDFNHLTAQVRQKLVELIDGQGTHTCVPLQGSGTFAVEAAIGTLMPRGGKLLCLVNGAYGKRIAQLTEVMGRRVTVKDFGESKAVDAEAVAVCLAQDDEITHVAVVYCETSTGILNPMEAISAAVAAAGKKLIIDAMSAFGALSISTAKLTFDAVIASSNKCLEGVPGMGFVLANIQSLEQAKGNSHSLSLDLHDQWQYMERTGQWRYTPPTHVLAALASALHQYDQEGGQAARLARYTENCQQLISGINGLGLRSFLAPEIQAPIIVTVHAPVHPNWQFNEFYQLTKDEGVVLYPGKLTDAETFRVGCIGAIGKAEIAMAIDAMARAFKQMGIETAAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYP5</accession>
    <name>A0A2S9GYP5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fumarylacetoacetate (FAA) hydrolase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2569</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92839">
        <property type="protein sequence ID" value="PRC92839"/>
        <property type="gene ID" value="S2091_2569"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.850.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041072">
        <property type="entry name" value="FAA_hydro_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011234">
        <property type="entry name" value="Fumarylacetoacetase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036663">
        <property type="entry name" value="Fumarylacetoacetase_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18288">
        <property type="entry name" value="FAA_hydro_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01557">
        <property type="entry name" value="FAA_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56529">
        <property type="entry name" value="SSF56529"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAA_hydro_N_2" evidence="2">
        <location>
            <begin position="1"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="domain" description="FAA_hydrolase" evidence="1">
        <location>
            <begin position="86"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="327" mass="35714" checksum="4475F030CF76C4CA" modified="2018-07-18" version="1">MKLATLKDGSRDGQLMVVSRDLKTAVIATNIAPSMQDLLDSWAFMAPQCDDLYVQLNQGRAANSFDFDPKNCMAPLPRAYQFADASAYVAYVELLSRARKLEMPAAFWSEPLMHQAASDDFIGACDDILLDNEAWGIDFESEIAVITGDVKMGSKPAQAAEQIRLLMLVNDVSLRELIPAEMEKGFGFFQSKPTTSFSPVAITPDELGEAWNAGKVHLPLRTSLNGKLVGQPNAGVDMTFNFPQLIAHLVKTRNARAGTIVASGAVFNKEGNKGHSSIYATRALEIIASDVATTPFMQFGDTIKIDMLDKNGKSLFGAIEQKLEQRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYX0</accession>
    <name>A0A2S9GYX0_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PINc domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2346</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92929">
        <property type="protein sequence ID" value="PRC92929"/>
        <property type="gene ID" value="S2091_2346"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09872">
        <property type="entry name" value="PIN_Sll0205-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002716">
        <property type="entry name" value="PIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041705">
        <property type="entry name" value="PIN_Sll0205"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01850">
        <property type="entry name" value="PIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="SSF88723"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PINc" evidence="1">
        <location>
            <begin position="4"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="128" mass="14189" checksum="81E9F659F67FB2B4" modified="2018-07-18" version="1">MKLLLDTQLLLWAAGEPERLSMEARSLIEITENELFFSAASLWEIAIKQSLGRDDFQVDARLLRRGLLDNGYSELPIGSEHAVAICSLPPIHKDPFDRMLVAQAMVEGIALLTSDSVVAQYPGPVRKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYY3</accession>
    <name>A0A2S9GYY3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Peptidase C39 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2576</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92846">
        <property type="protein sequence ID" value="PRC92846"/>
        <property type="gene ID" value="S2091_2576"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005074">
        <property type="entry name" value="Peptidase_C39"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03412">
        <property type="entry name" value="Peptidase_C39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase C39" evidence="1">
        <location>
            <begin position="11"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03412"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="139" mass="15836" checksum="533C1FAED258DA3A" modified="2018-07-18" version="1">MNTIDKGDLRASFEDMARILPQFGFRGVGYSASFEQLTKLKVPVIVYLKYRKNDHFSVLRGIDNDTVWLADSSTGNRYYSRSQFMAMWETRNAETLKGKILVILPTQVDVSAKSDFFTSSPKRPTALSTKLQSVRNFLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZ04</accession>
    <name>A0A2S9GZ04_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ferredoxin--NADP reductase</fullName>
            <shortName evidence="2">FNR</shortName>
            <shortName evidence="2">Fd-NADP(+) reductase</shortName>
            <ecNumber evidence="2">1.18.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2357</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>H(+) + NADP(+) + 2 reduced [2Fe-2S]-[ferredoxin] = NADPH + 2 oxidized [2Fe-2S]-[ferredoxin]</text>
            <dbReference type="Rhea" id="RHEA:20125"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.18.1.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="2">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ferredoxin--NADP reductase type 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.18.1.2" evidence="2"/>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92940">
        <property type="protein sequence ID" value="PRC92940"/>
        <property type="gene ID" value="S2091_2357"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004324">
        <property type="term" value="F:ferredoxin-NADP+ reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01685">
        <property type="entry name" value="FENR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022890">
        <property type="entry name" value="Fd--NADP_Rdtase_type_2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="1 2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="2">
        <location>
            <position position="44"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="52"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="57"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="97"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="132"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="298"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="339"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="356" mass="39119" checksum="0219C730B7E383CC" modified="2018-07-18" version="1">METKLANESLAPIIADAVIVGAGPVGLFQVFELGLLEIKAHVIDSLPMVGGQCVELYPDKPIYDIPAVPVCTGQELVDNLLKQIEPFSPTFHLGQEVTLVARREDGRFDLETSTGTRFITKTIFIAAGVGSFQPRTLKVDGIEAFDGSQLFYRVKDPLRFHGRNIVICGGGDSALDWALDLVGKAESVVLLHRRDDFRAAPASVTKMRDLCEQLEMQLIIGQITGIETKDDLLSEIKVTGQDGVTRRLPLDDLLVFYGLSPKLGPIADWSLEIERKQLKVMNTEKFETNIPGIFAVGDINTYPGKKKLILSGFHEAALAAFGAAPYIFPDKKIHMQYTTTSPKLHKILGVETPVFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZ06</accession>
    <name>A0A2S9GZ06_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Chemotaxis protein CheA</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">S2091_2386</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92969">
        <property type="protein sequence ID" value="PRC92969"/>
        <property type="gene ID" value="S2091_2386"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00088">
        <property type="entry name" value="HPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.560">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.400">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004105">
        <property type="entry name" value="CheA-like_dim"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037006">
        <property type="entry name" value="CheA-like_homodim_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036061">
        <property type="entry name" value="CheW-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002545">
        <property type="entry name" value="CheW-lke_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015162">
        <property type="entry name" value="CheY-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035891">
        <property type="entry name" value="CheY-binding_CheA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036641">
        <property type="entry name" value="HPT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008207">
        <property type="entry name" value="Sig_transdc_His_kin_Hpt_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01584">
        <property type="entry name" value="CheW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09078">
        <property type="entry name" value="CheY-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02895">
        <property type="entry name" value="H-kinase_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01627">
        <property type="entry name" value="Hpt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00260">
        <property type="entry name" value="CheW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01231">
        <property type="entry name" value="H-kinase_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00073">
        <property type="entry name" value="HPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47226">
        <property type="entry name" value="SSF47226"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50341">
        <property type="entry name" value="SSF50341"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55052">
        <property type="entry name" value="SSF55052"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50851">
        <property type="entry name" value="CHEW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50894">
        <property type="entry name" value="HPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0145">Chemotaxis</keyword>
    <keyword evidence="13" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0902">Two-component regulatory system</keyword>
    <feature type="domain" description="HPt" evidence="12">
        <location>
            <begin position="1"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="10">
        <location>
            <begin position="362"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="domain" description="CheW-like" evidence="11">
        <location>
            <begin position="572"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="280"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="285"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="modified residue" description="Phosphohistidine" evidence="8">
        <location>
            <position position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PRC92969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="706" mass="77455" checksum="0B0C042A12BB3D16" modified="2018-07-18" version="1">MSIDMSQFYQVFFDEAEELLAEMEKLLLAVNIAEPDSEDLNAIFRTAHSIKGGASTFGITDMSDVTHFLESLLDNIRKGEMAITSEHVDAFLVAKDILKMQLNGHKFGAEVDQEAVADVRMMLQSLAQHSVTKIAPPPKVEKAVPKNSKEQYKKCYRVEFPKVSETDLETLGEELSLLGDISKEALDDHRFAFVLNTNAVPDDIIAICSFILDPEDLFITEIAIANIPPREANEDELGYGFFDPIEKPGDEQPDEEKLGYGFFEPIDPAFALDRTPGELMKGLPAKSENKSDKAEHAQLNGSAEHHTATKKDGDKAAGNQESTTIRVGIEKVDQLINLIGELVITQAMLEQRTATLDPLEHERLLSSIGQLTRNTRDLQEAVMSIRMMPMDYVFSRFPRMVRDLASKLGKKVEFVTYGASTELDKGLIERIVDPLTHLVRNSIDHGIEMPQVRLAEGKYEAGKLSLSASHQGGNIVIEVSDDGGGLNRDRIIAKAREQGLVAPDNMPDADVWQLIFAPGFSTAEVVTDVSGRGVGMDVVKRNITNMGGVVDIRSAKGFGTTIVISLPLTLAILDGMSIRVGEEVYILPLGYVVESLQPVADDIKVISGKGTVVKVRNEYLPLIALHQLFEIKAKYTDPCQGILVILEVDGKQAALFIDELVGQQQVVVKNIESNYKKIPSVSGATILGDGCVALILDVSALLRTTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZ68</accession>
    <name>A0A2S9GZ68_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative hemolysin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2107</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93021">
        <property type="protein sequence ID" value="PRC93021"/>
        <property type="gene ID" value="S2091_2107"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="255" mass="28777" checksum="7BAB0A76E4D0E2B0" modified="2018-07-18" version="1">MRLLTSTSEQNSNFSKLSLSLASSPEEVREVQRLRYKVFIETMGLSTLENPEGLDKDEFDDYCDHLIVRDSKNLKIVGTYRVLGPHSARKIGRYYSESEFDLSRFAHIRDQIAEAGRACIHPDYRSGAVIMMLWAGLAAFMRREQCNYLVGCASISLADGGMNANALFNSLKPEEMAPIEYRVTPILPFPLSGEVDGSFQKNVPPLLKGYLRAGAWVCGEPAWDPDFHCADLFLLLPLENLDGRYSRHYLKDKAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZM1</accession>
    <name>A0A2S9GZM1_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">3-isopropylmalate dehydrogenase</fullName>
            <ecNumber evidence="13">1.1.1.85</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">3-IPM-DH</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Beta-IPM dehydrogenase</fullName>
            <shortName evidence="13">IMDH</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">leuB</name>
        <name evidence="16" type="ORF">S2091_2239</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13 14">Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 13 14">
            <text>(2R,3S)-3-isopropylmalate + NAD(+) = 4-methyl-2-oxopentanoate + CO2 + NADH</text>
            <dbReference type="Rhea" id="RHEA:32271"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:17865"/>
            <dbReference type="ChEBI" id="CHEBI:35121"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.85"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13 14">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="13 14">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="13 14">Binds 1 Mg(2+) or Mn(2+) ion per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 13 14">Amino-acid biosynthesis; L-leucine biosynthesis; L-leucine from 3-methyl-2-oxobutanoate: step 3/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5 13 14">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="13">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 13">Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.85" evidence="13"/>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93153">
        <property type="protein sequence ID" value="PRC93153"/>
        <property type="gene ID" value="S2091_2239"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00048">
        <property type="reaction ID" value="UER00072"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003862">
        <property type="term" value="F:3-isopropylmalate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009098">
        <property type="term" value="P:leucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01033">
        <property type="entry name" value="LeuB_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019818">
        <property type="entry name" value="IsoCit/isopropylmalate_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024084">
        <property type="entry name" value="IsoPropMal-DH-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004429">
        <property type="entry name" value="Isopropylmalate_DH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42979">
        <property type="entry name" value="PTHR42979"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00180">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01329">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00169">
        <property type="entry name" value="leuB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00470">
        <property type="entry name" value="IDH_IMDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 13" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="12 13 14" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="13" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 13 14" id="KW-0432">Leucine biosynthesis</keyword>
    <keyword evidence="9 13" id="KW-0460">Magnesium</keyword>
    <keyword evidence="13" id="KW-0464">Manganese</keyword>
    <keyword evidence="8 13 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11 13 14" id="KW-0520">NAD</keyword>
    <keyword evidence="10 13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Iso_dh" evidence="15">
        <location>
            <begin position="2"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="90"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="100"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="128"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="222"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="246"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="250"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="280"/>
            <end position="292"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="site" description="Important for catalysis" evidence="13">
        <location>
            <position position="135"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalysis" evidence="13">
        <location>
            <position position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU004445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM01329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="PRC93153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="356" mass="38385" checksum="21F0AC060AD983AF" modified="2018-07-18" version="1">MKIAILPGDGIGPEIVAQAVNVLNVLGESFEMETAPVGGAGYAAHGHPLPEATLTLAKQADAILLGAVGDWKYDTLERALRPEQAILGLRKHLNLFANLRPAILYPELAGASTLKPEIVSGLDILIIRELTGDVYFGQPRGVRIATDGAFIGEREGFDTMRYAETEIRRIAHVAFQAAQKRDKRLTSVDKANVLETFQFWKDIVTEVHQEYPDVALDHMYIDNASMQLIRAPKKFDVIVTGNMFGDILSDAAAMLTGSIGMLPSASLDANNKGLYEPSHGSAPDIAGKGIANPLATILSAAMMLRFTLAKPEQADRIETAVKKVLAQGLRTPDIYEPGTTKVGTEEMGNAVVRALT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZW2</accession>
    <name>A0A2S9GZW2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Site-specific recombinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_1978</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93240">
        <property type="protein sequence ID" value="PRC93240"/>
        <property type="gene ID" value="S2091_1978"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1080.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023271">
        <property type="entry name" value="Aquaporin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011385">
        <property type="entry name" value="Site-sp_rcmbase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10136">
        <property type="entry name" value="SpecificRecomb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015380">
        <property type="entry name" value="Site-sp_rcmb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="371"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="431"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="473"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="541"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="596"/>
            <end position="621"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC93240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="669" mass="75671" checksum="D363555BA315D7A2" modified="2018-07-18" version="1">MSIDFILEQIANTPTSSDTELIRDLVAAIRPKHADNIELATDRLHALSFKLTAQPKYAVALRNYLFELVSSRKITHLCTDTGITLSEGFWSAAWQRLLYKFLPPLVNNDYLRDVIGTIFHQVDDHVWINGVDEQVWLDLIDAIGFRIRGAHVKQKSNLNELMSAMQVLSYRISAIGLESELVRNYPSIERYESPFLRQNDEINDYIKEYRNWVVDHSAVHRDSQQIEVLLAQCEEIVIKIRRTAAQQGVSVSLTRLLLRVTESIARLRIMLALIEAPNKKQTLHIGFRLFKELVYFDNRKYSIRELIGTNTQLLTMQVTEHAGRSGEHYVASNRREWVEMLRSASGAGFIVGFMATMKILMSKLLLAPFGYAFLFSLNYSLGFMLVHIMHFTIATKQPAMTAALIAKSLDQSKHKLDDLCELVVQVIRTQFIAILGNVAIAIPTAYAIAWAWYSSTGHHLVDPDKARHLLDDINPFASLSLFHAAIAGVCLFLSGLISGYYDNKASYSHIPERLLQLSSMQWLFGMARWKRMTDYIGNNLGALAGNFFFGIMLGSIGQIGVFLGLPIDIRHITFSSANFAFALVGLEHQLTWQVWVISLVGIVLIGIVNLAVSFSLALFVAMRSRGVSFEQTGELIALLWKRFIKHGRDFFFPPKEMDLPESGSEHGKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0I3</accession>
    <name>A0A2S9H0I3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acetyltransferase (GNAT) domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1879</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93492">
        <property type="protein sequence ID" value="PRC93492"/>
        <property type="gene ID" value="S2091_1879"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13673">
        <property type="entry name" value="Acetyltransf_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="10"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="169" mass="18784" checksum="AD90FE98A94F20D6" modified="2018-07-18" version="1">MTDADNLIGLHIRQAQITEADDLTRLAMESKAHWNYTAEQLALWRSELTVPHEVIAAGRAYVGEIDHTLAAMMVLSPAAMTWKLNYFFVGPAWMNRGIGKTMFQFAIEMARKQGARAVSIDADPNAEPFYLLCGAIRSHTINAPIAEDSNRIRPQMLFAIPTKKAGLPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0J7</accession>
    <name>A0A2S9H0J7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1888</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93501">
        <property type="protein sequence ID" value="PRC93501"/>
        <property type="gene ID" value="S2091_1888"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="92" mass="10537" checksum="1E7A54C366DC1C08" modified="2018-07-18" version="1">MAIFSDAQQMHKMYPATFEAPSSDELSEVRVGSLVKICADDIERFWVKVTDVKGDRLQGTVDNNLLHSDAHQLKSDDVVSFELRHIYQVFHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H113</accession>
    <name>A0A2S9H113_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Integral membrane protein CcmA involved in cell shape determination</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1670</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93669">
        <property type="protein sequence ID" value="PRC93669"/>
        <property type="gene ID" value="S2091_1670"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007607">
        <property type="entry name" value="BacA/B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35024">
        <property type="entry name" value="PTHR35024"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04519">
        <property type="entry name" value="Bactofilin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="132" mass="14034" checksum="020029D7436B2F43" modified="2018-07-18" version="1">MFNRKNKSTIDSLIGLSTNIDGNLYFKGGLRIDGSVKGNVIAEDEHGSMLIISENAMICGEVRAAHIVVDGSILGPVFSSELLELLPKARITGDVHYKALEMNSGATVTGQLTHTQTSNSTESVLQLSSSQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H189</accession>
    <name>A0A2S9H189_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative phosphotransferase related to Ser/Thr protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1364</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93755">
        <property type="protein sequence ID" value="PRC93755"/>
        <property type="gene ID" value="S2091_1364"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="APH" evidence="1">
        <location>
            <begin position="41"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="351" mass="40185" checksum="47A7393456DB4608" modified="2018-07-18" version="1">MTSSKNKQITSPATTNSDPRLALLVDWIATLSEFPLLTTTMRPASTDASFRRYFRINDALGKSYILMDAPPPQEDVRPFIHIAQLFGDTGVTVPHILASHPEHGFLLLSDLGTVMYSHLLNQDTAQKLYMDAIDSLVQIQLHSQPEVLPEYDRAMQLKELMLFPEWYIGKHLGATLTPTQQASLDKVFEQILANTMAQPQVYVHRDYHSRNLMVMKEGNPGVLDFQGALYGPITYDIVSLLRDAYIEWDEEQVLDWAIRYWERARHAGLPISTDIDSFYRDFEFMGLQRHLKILGIFSRLAYRDGKDNYLADLPLVLSYVRKTAQRYNTLIPLLRILDELADTAPQVGYTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1D4</accession>
    <name>A0A2S9H1D4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative metal-dependent hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1369</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93760">
        <property type="protein sequence ID" value="PRC93760"/>
        <property type="gene ID" value="S2091_1369"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002725">
        <property type="entry name" value="YgjP-like_metallopeptidase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01863">
        <property type="entry name" value="DUF45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF45" evidence="1">
        <location>
            <begin position="66"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="281" mass="31957" checksum="2E49B8527C66AEEA" modified="2018-07-18" version="1">MAGSSFSPLSALAKFVQFDLFEPLARNLIEVAPQAELPKVLELHPHGVQLGTHYVPYQLIRSKRRSIGFLITDEGLRITAPRWVGLAEINAAILSKQRWVLTKLQEQQDRPKPQTEVETIWTDGATLPFLGQTATLRVQFGAATQFDSATGLITLNLPSDANPAQCKKHLLAWLTSQARRKFSERLPYFAEQLCVQYHSFTLTSANTRWGSCNSQGKIRLNWRLIHFSPHLIDYVIAHELAHLHEMNHSPRFWATVERVFPDYVAAREELKHLGMKALPQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1D9</accession>
    <name>A0A2S9H1D9_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE</fullName>
            <ecNumber evidence="6">2.1.1.163</ecNumber>
            <ecNumber evidence="6">2.1.1.201</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">2-methoxy-6-polyprenyl-1,4-benzoquinol methylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Demethylmenaquinone methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ubiE</name>
        <name evidence="7" type="ORF">S2091_1413</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>a 2-demethylmenaquinol + S-adenosyl-L-methionine = a menaquinol + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42640"/>
            <dbReference type="Rhea" id="RHEA-COMP:9539"/>
            <dbReference type="Rhea" id="RHEA-COMP:9563"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18151"/>
            <dbReference type="ChEBI" id="CHEBI:55437"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="EC" id="2.1.1.163"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>a 2-methoxy-6-all-trans-polyprenyl-1,4-benzoquinol + S-adenosyl-L-methionine = a 6-methoxy-3-methyl-2-all-trans-polyprenyl-1,4-benzoquinol + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:28286"/>
            <dbReference type="Rhea" id="RHEA-COMP:10858"/>
            <dbReference type="Rhea" id="RHEA-COMP:10859"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:84166"/>
            <dbReference type="ChEBI" id="CHEBI:84167"/>
            <dbReference type="EC" id="2.1.1.201"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="6">Cofactor biosynthesis; ubiquinone biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="6">Quinol/quinone metabolism; menaquinone biosynthesis; menaquinol from 1,4-dihydroxy-2-naphthoate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.163" evidence="6"/>
    <dbReference type="EC" id="2.1.1.201" evidence="6"/>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93804">
        <property type="protein sequence ID" value="PRC93804"/>
        <property type="gene ID" value="S2091_1413"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00079">
        <property type="reaction ID" value="UER00169"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00232"/>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043333">
        <property type="term" value="F:2-octaprenyl-6-methoxy-1,4-benzoquinone methylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043770">
        <property type="term" value="F:demethylmenaquinone methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102094">
        <property type="term" value="F:S-adenosylmethionine:2-demethylmenaquinol methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102955">
        <property type="term" value="F:S-adenosylmethionine:2-demethylmenaquinol-7 methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102027">
        <property type="term" value="F:S-adenosylmethionine:2-demethylquinol-8 methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009060">
        <property type="term" value="P:aerobic respiration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009234">
        <property type="term" value="P:menaquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006744">
        <property type="term" value="P:ubiquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01813">
        <property type="entry name" value="MenG_UbiE_methyltr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004033">
        <property type="entry name" value="UbiE/COQ5_MeTrFase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023576">
        <property type="entry name" value="UbiE/COQ5_MeTrFase_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01209">
        <property type="entry name" value="Ubie_methyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01934">
        <property type="entry name" value="MenG_MenH_UbiE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51608">
        <property type="entry name" value="SAM_MT_UBIE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01183">
        <property type="entry name" value="UBIE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01184">
        <property type="entry name" value="UBIE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0474">Menaquinone biosynthesis</keyword>
    <keyword evidence="2 6 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 6 7" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0830">Ubiquinone</keyword>
    <keyword evidence="4 6" id="KW-0831">Ubiquinone biosynthesis</keyword>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="6">
        <location>
            <begin position="117"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="70"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="91"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022428"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC93804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="244" mass="27044" checksum="0BF7ED5893C32FD3" modified="2018-07-18" version="1">MTNTTHFGYSTVEENEKVHKVAEVFHSVAAKYDVMNDLMSAGLHRAWKIFAIAQAGVRTGFKVLDIAGGTGDLSKEFAKQAGPTGEVWLTDINESMLRVGRDRLLNKGIITPTLLCDAEKIPFPDNYFDRVTVAFGLRNMTHKDAALAEMHRVLKPGGKLLVLEFSKVASALQKPYDVYSFSVLPWLGKMIANDADSYRYLAESIRMHPDQETLKTMMQEAGLECVNYFNLSAGVAALHTGIKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1M0</accession>
    <name>A0A2S9H1M0_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Penicillin-binding protein 1A</fullName>
            <ecNumber evidence="7">2.4.1.129</ecNumber>
            <ecNumber evidence="6">3.4.16.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="26" type="ORF">S2091_1459</name>
    </gene>
    <organism evidence="26 27">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="26 27" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="26 27">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="21">
            <text>[GlcNAc-(1-&gt;4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n)-di-trans,octa-cis-undecaprenyl diphosphate + beta-D-GlcNAc-(1-&gt;4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate = [GlcNAc-(1-&gt;4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n+1)-di-trans-octa-cis-undecaprenyl diphosphate + di-trans,octa-cis-undecaprenyl diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23708"/>
            <dbReference type="Rhea" id="RHEA-COMP:9602"/>
            <dbReference type="Rhea" id="RHEA-COMP:9603"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58405"/>
            <dbReference type="ChEBI" id="CHEBI:60033"/>
            <dbReference type="ChEBI" id="CHEBI:78435"/>
            <dbReference type="EC" id="2.4.1.129"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">In the C-terminal section; belongs to the transpeptidase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">In the N-terminal section; belongs to the glycosyltransferase 51 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="26">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.129" evidence="7"/>
    <dbReference type="EC" id="3.4.16.4" evidence="6"/>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93850">
        <property type="protein sequence ID" value="PRC93850"/>
        <property type="gene ID" value="S2091_1459"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008658">
        <property type="term" value="F:penicillin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008955">
        <property type="term" value="F:peptidoglycan glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009002">
        <property type="term" value="F:serine-type D-Ala-D-Ala carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046677">
        <property type="term" value="P:response to antibiotic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3810.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001264">
        <property type="entry name" value="Glyco_trans_51"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023346">
        <property type="entry name" value="Lysozyme-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036950">
        <property type="entry name" value="PBP_transglycosylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031376">
        <property type="entry name" value="PCB_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001460">
        <property type="entry name" value="PCN-bd_Tpept"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17092">
        <property type="entry name" value="PCB_OB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00912">
        <property type="entry name" value="Transgly"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00905">
        <property type="entry name" value="Transpeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53955">
        <property type="entry name" value="SSF53955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="18" id="KW-0046">Antibiotic resistance</keyword>
    <keyword evidence="9" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="14" id="KW-0133">Cell shape</keyword>
    <keyword evidence="20" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="11 26" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="13 26" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="22" id="KW-0472">Membrane</keyword>
    <keyword evidence="19" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="16" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="10" id="KW-0645">Protease</keyword>
    <keyword evidence="27" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="15" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="26" id="KW-0808">Transferase</keyword>
    <keyword evidence="12 22" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="17 22" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="22">
        <location>
            <begin position="18"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="domain" description="Transgly" evidence="24">
        <location>
            <begin position="69"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="domain" description="PCB_OB" evidence="25">
        <location>
            <begin position="328"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="domain" description="Transpeptidase" evidence="23">
        <location>
            <begin position="434"/>
            <end position="707"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00007739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00012555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00018638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00023251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00023988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="Pfam" id="PF00905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="24">
        <source>
            <dbReference type="Pfam" id="PF00912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="25">
        <source>
            <dbReference type="Pfam" id="PF17092"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="26">
        <source>
            <dbReference type="EMBL" id="PRC93850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="27">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="788" mass="86743" checksum="435B5F16B5865B48" modified="2018-07-18" version="1">MRPAAQQTTSELPFRLKFILGFSIGLILAASLAGGYWLRQAWRQLPAVDHLNQYSPALPLRIYSSEGILLAEYGEERRQFLPIEKIPLVMRQALLAIEDARFYEHGAVDFTGLLRATLANLGSGRQGQGASTISMQVARSFFLTREKTLQRKLNEILLSYKLEQRYSKDKLLELYMNQIYLGERSYGFAAASNIYFDKPLEQISVAEAAMLAGLPKAPSAYNPVANPQRAATRQHYILQRMLELGYIKPEAYQQAMEEKLILNPSRNSSVQEAAYAVEEARQLVMQLYQERAYTMGLDVTTTIQMAPQLAADKQLRSGLLDAQGRRGYRGPEAQLGTSAHKHANSTLNKLLLPYPDSGEILAALVTEVSPKQIKAVLRNGRVLQIGAIDPRIAGGWAKLPASGKRMISVGSVIRTYRDSSERWLLSQAPEMEGALISVDAKTGDILALAGGFDFFRNPFNHALQAYRQPGSSFKPFVYSAALEKGYFPGTMVDDTQRVLLPQDTGARSWRPRNFGDNYEGFITVRRGLMRSKNLVAVSLMQASGAAYVQEFATQFSFLPERNPVSLPLALGAGAVTPLQLAQSYAVFANGGYAQAPRLIKEIRDRSGQVLFADSARKNPGKKVVSARNAYIMDSMLQDVVKAGTGHGAKVLARGDTAGKTGTSNNAYDAWFAGYSSGVVSVVWLGYDQPKSLGNTTGGVAALPIWSRYMQVAVKDRNEYWQEEPAGLSVVDGDYVYSEYLMGSCVADSYPFIHSKLTCQAGGSSDLTLEKEALNAAQEREQILKLFSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1N5</accession>
    <name>A0A2S9H1N5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Growth inhibitor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1385</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93776">
        <property type="protein sequence ID" value="PRC93776"/>
        <property type="gene ID" value="S2091_1385"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003477">
        <property type="entry name" value="PemK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011067">
        <property type="entry name" value="Plasmid_toxin/cell-grow_inhib"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33988">
        <property type="entry name" value="PTHR33988"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02452">
        <property type="entry name" value="PemK_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF033490">
        <property type="entry name" value="MazF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="87" mass="9464" checksum="227B477B1226692A" modified="2018-07-18" version="1">MKRGEVWCVEFDPAVGSEIRKTRPAVIVSNDAANQHMARVQVVPISSNTDRIYPSETVITLAGQKNKVMADQIMTAANCVSRLCSAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1T0</accession>
    <name>A0A2S9H1T0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Enoyl-CoA hydratase/carnithine racemase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1105</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the enoyl-CoA hydratase/isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC93932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93932">
        <property type="protein sequence ID" value="PRC93932"/>
        <property type="gene ID" value="S2091_1105"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.12.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018376">
        <property type="entry name" value="Enoyl-CoA_hyd/isom_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014748">
        <property type="entry name" value="Enoyl-CoA_hydra_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00166">
        <property type="entry name" value="ENOYL_COA_HYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="258" mass="28456" checksum="2C7DDB47536B9463" modified="2018-07-18" version="1">MNYEAILVETKGKVGVITLNRPKALNALNDQLMDELGHALNEFDKNEQIGCIVLTGSEKAFAAGADITLMVNYTYMDAFNGNYVTRNWEHIRQIRKPVIAAVAGYALGGGCELAMMCDFIIAAENAKFGQPEIKLATIPGCGGTQRLPRAISKSKAMDMCLTARMMDAVEAERAGLVSRVVPLDKLMEETLAAATTIAGMSLPIVMMIKDSVNRAYETTLSEGVQYERRMFYSTFASEDQKEGMKSFLEKRLPNFRNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H280</accession>
    <name>A0A2S9H280_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1265</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94092">
        <property type="protein sequence ID" value="PRC94092"/>
        <property type="gene ID" value="S2091_1265"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="289" mass="32719" checksum="DEFFAF1C15CFDB0C" modified="2018-07-18" version="1">MLNTSTAAISRSIQKLEKELGVRLLNRTTRKIGCTDEGMALYRDTQAALLQMNRALTAAKQSRTDARGLLRITCARNFGRKFIAPLAISFRKSYPEIDIDLSLDDDVIDLIEHGADMAIRGGHREDSRLIYRSLAIMPFYVCATPKYLAREGTPIQSADIAHHKCVAFKVGVSSEPMRWEFDDSGKLYRMEVRGSFSVNDIESACQAALADEGLVQLPGYLAVEHIRAGRLRPVLLDQLSRHRSFSITYVNRRELQPLRDTLFADYIYQSLRDEKLFSLTAQELQNFIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H296</accession>
    <name>A0A2S9H296_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">3-hydroxyisobutyrate dehydrogenase</fullName>
            <shortName evidence="6">HIBADH</shortName>
            <ecNumber evidence="6">1.1.1.31</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_1250</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>3-hydroxy-2-methylpropanoate + NAD(+) = 2-methyl-3-oxopropanoate + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:17681"/>
            <dbReference type="ChEBI" id="CHEBI:11805"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57700"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.31"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="6">Amino-acid degradation; L-valine degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the HIBADH-related family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.31" evidence="6"/>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94077">
        <property type="protein sequence ID" value="PRC94077"/>
        <property type="gene ID" value="S2091_1250"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00362"/>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008442">
        <property type="term" value="F:3-hydroxyisobutyrate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006574">
        <property type="term" value="P:valine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002204">
        <property type="entry name" value="3-OH-isobutyrate_DH-rel_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006115">
        <property type="entry name" value="6PGDH_NADP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011548">
        <property type="entry name" value="HIBADH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015815">
        <property type="entry name" value="HIBADH-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029154">
        <property type="entry name" value="NADP-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14833">
        <property type="entry name" value="NAD_binding_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03446">
        <property type="entry name" value="NAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000103">
        <property type="entry name" value="HIBADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01692">
        <property type="entry name" value="HIBADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00895">
        <property type="entry name" value="3_HYDROXYISOBUT_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0101">Branched-chain amino acid catabolism</keyword>
    <keyword evidence="4 6" id="KW-0520">NAD</keyword>
    <keyword evidence="3 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD_binding_2" evidence="7">
        <location>
            <begin position="8"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="domain" description="NAD_binding_11" evidence="8">
        <location>
            <begin position="170"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000103-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU910714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF14833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC94077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="306" mass="30890" checksum="FA5CBF7AA0A50695" modified="2018-07-18" version="1">MSNIVMSNIAFIGLGNMGAPMAHNLVKAGHTVTVYDLSQAAVARLVEAGAHPASSASAALDNAEIVISMLPASAHVESLYLGENGILAQIPEGTLIIDCSTIAPQVARKVALAAAAKGLSMIDAPVSGGTAGAAAGTLTFIVGGSSAALELARPVLSAMGKNIFHAGDYGAGQTAKICNNMLLGVLMAGTSEALALGVANGLDPKVLSDIMSKSSGRNWALEVYNPYPGVMENVPASKHYAGGFGVDLMLKDLGLAAEAALTARASIPLGELARNLYSLHSQGGSGSLDFSSILKLIAPANLDKPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2F3</accession>
    <name>A0A2S9H2F3_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">50S ribosomal protein L23</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rplW</name>
        <name evidence="6" type="ORF">S2091_1313</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the universal ribosomal protein uL23 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94140">
        <property type="protein sequence ID" value="PRC94140"/>
        <property type="gene ID" value="S2091_1313"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01369_B">
        <property type="entry name" value="Ribosomal_L23_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012678">
        <property type="entry name" value="Ribosomal_L23/L15e_core_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013025">
        <property type="entry name" value="Ribosomal_L25/23"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11620">
        <property type="entry name" value="PTHR11620"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00276">
        <property type="entry name" value="Ribosomal_L23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54189">
        <property type="entry name" value="SSF54189"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC94140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="104" mass="11761" checksum="B37A12EA1498B890" modified="2018-07-18" version="1">MSTLVKFSEERLLKVLLAPVISEKATMVAEKNEQVVFRVSPDATKPEIKAAVEMLFKVQVESVQVANRQGKQKRSGRFTGRRNHTKRAFVCLKPGQEINFTEEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2L1</accession>
    <name>A0A2S9H2L1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0840</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94219">
        <property type="protein sequence ID" value="PRC94219"/>
        <property type="gene ID" value="S2091_0840"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015648443" evidence="1">
        <location>
            <begin position="26"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="365" mass="37900" checksum="6E901FB6568AA399" modified="2018-07-18" version="1">MKRRFNQITLSRFTLIFLITINLVACGGSSSPSSTSAGSTGTGSSGTGSTSSSSSSSLVYANLQQASLGVGASLNGAVPFPADNAWNTNISGAPVDPNSDALIASIGINTGLHPNFGSALWDGAPNGIPYVVVSSSQALVPVNFAAYPTESDPGPYPIPANAPIEGQLVSGAAFGGDRHVLVVDRDTNRLYETYNSYPNTNGSWTADSGAIFHLDSDNVRPTAALGWTSADAAGLPIFPGLARYDEVGAGLIAHALRFTVANSRQAYVPPANHWASSSTNPNLPPMGMRVRLKASYVIPSSFSKDSQVILQALKTYGLIVADNGSNWYITGAPDARWNDSALVSELGSVLGSNFEVVQMTGLVTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2N1</accession>
    <name>A0A2S9H2N1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0860</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94239">
        <property type="protein sequence ID" value="PRC94239"/>
        <property type="gene ID" value="S2091_0860"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010281">
        <property type="entry name" value="DUF885"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33361">
        <property type="entry name" value="PTHR33361"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05960">
        <property type="entry name" value="DUF885"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015404714" evidence="1">
        <location>
            <begin position="20"/>
            <end position="580"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="580" mass="65119" checksum="A60DCE6C4907EE0E" modified="2018-07-18" version="1">MKKIISSIAIALACTAAYANTPQLDTLFESDWQWTLSHSPETATTLGDNRYNHKLSNTSLAAARVYNKHQQDMLKEALKIKRDSLSGQELISYDQFVLEKQQAIRAAELYPYTVQPITQIDGLQITLPSLVSQTPFNNAFDYHNYLARLHAIPAYVDGIIEQLQENMKTGWVAPKVIIAPVPGQLHDLRLHLDESEFGTPFHHIPANVPRPEVFAARGKKELSEHVAPALLKLENFLITQYLPACRDSIAASSLPAGMPYYDFMVKNGTTTDLTAQQIHDIGLTEVARIKAEMQRVMDQVGFKGSFAEFTVFLNTDPRFFYTNSDDLLNGFRDIIAHVYQVLPTMFAHLPKAQAEVKPIPLLGSEQQPAAYYNPGPDDGSRSGYFAVNVSNLNTRAKWEMETLTLHEAIPGHHLQISIAKEATDLPKFRRNGWYNAFGEGWALYSEGLGYEMGFYKDPYSKFGNLNDELFRAARLVVDTGIHALGWSREQAITYLNENTANPPNDNQVEIDRYIAWPGQALGYKIGQLKINQLRAKATTALGDKFDLRAFHNAVIDNGPIPLSVLETQIDLWISQQQAKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2W8</accession>
    <name>A0A2S9H2W8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cupin domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0827</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94206">
        <property type="protein sequence ID" value="PRC94206"/>
        <property type="gene ID" value="S2091_0827"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013096">
        <property type="entry name" value="Cupin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07883">
        <property type="entry name" value="Cupin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cupin_2" evidence="1">
        <location>
            <begin position="36"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="123" mass="13736" checksum="BE967FCA2862F715" modified="2018-07-18" version="1">MNLTDWNTALDTCIYDSTVGIKIAKLAGDAFLSTYLTSIDPGKSVNAHYHKKGNEHYHIIQGSGEMTLVDVGSKALTKVDVYHHQSFVVQENTLHQLKNTGNTKLVLMFSCPESHLNEDRFLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2Y2</accession>
    <name>A0A2S9H2Y2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ankyrin repeats (3 copies)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0938</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94317">
        <property type="protein sequence ID" value="PRC94317"/>
        <property type="gene ID" value="S2091_0938"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.30">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009091">
        <property type="entry name" value="RCC1/BLIP-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000408">
        <property type="entry name" value="Reg_chr_condens"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13637">
        <property type="entry name" value="Ank_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00633">
        <property type="entry name" value="RCCNDNSATION"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="SSF48403"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50985">
        <property type="entry name" value="SSF50985"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00626">
        <property type="entry name" value="RCC1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50012">
        <property type="entry name" value="RCC1_3"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015710501" evidence="2">
        <location>
            <begin position="22"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="494"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="561"/>
            <end position="593"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="621" mass="66994" checksum="15DCF6040FAD5219" modified="2018-07-18" version="1">MATIKTSIFFLFFLCLVDAHSAEPQISAGRYHNLGLASDGTVYWWGNDQGTRNFIRIPIEPKSPMRVDGLPRIQSVAAGWQHSVAIAEDGSVYEWGFSPYNEYQVLMRQPLLGVCELERLLSGGHGKNPCAEEEIARATKIYVAKPIRIAGIPPAAIVAALDDTTIIVSRDGNVYCWSGVSAPQQIIGLEKIKAIGLGQFHGVALRDDGAVLTWGHENNGKLGHSSAPDESICFNPKPQVAFTQAAGIGAGVESTYAYRADGTVWGWGDPWSEQLGFKTTARKKTDPTTSAPRHIATVNEIVQLATGGSTVIARTAEGKLISWGVHYESVRDLPMGLRKNVMSLVTPQMSQIKALSTYDHTLTLTQDGFVCAWGGNTYGETRPDNKRRSIQGAVPVLLADGQTPLNLFNDKNALPTQLCGDEHWRGRIALWEADELEIKRSENREQALAAKVGFVTPNWFGRSAVISAVALHNRKALESLLATGECDLNIQDANGLTALHNALLKESDSGLATLLLDRGANPKLISVTGLSTLMLAAENQGPILFKRLISLGVPVDAKNADGSTALMYAVAGKNVENVRLLIAQGADVNSQNMSGDTALSIAQYEDQIEIVHLLQKAGAVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H314</accession>
    <name>A0A2S9H314_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Autoinducer binding domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0993</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94372">
        <property type="protein sequence ID" value="PRC94372"/>
        <property type="gene ID" value="S2091_0993"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005143">
        <property type="entry name" value="TF_LuxR_autoind-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036693">
        <property type="entry name" value="TF_LuxR_autoind-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03472">
        <property type="entry name" value="Autoind_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75516">
        <property type="entry name" value="SSF75516"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH luxR-type" evidence="2">
        <location>
            <begin position="183"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="254" mass="28114" checksum="A3A235CC7A6717D2" modified="2018-07-18" version="1">MDEVFGNSGVAPDFFTTYDALMNARDETDTITRLQTAAQGLGFDKVLFAVIPQPKVNIADIYLRSNYPDKWREHYDRNNLSAADPTVEYCFKSSSPFVWMPQSFKTTEQQALYEEAASFGLKVGVTLPIRGIAGEVGMLTCVRDENPGPAFLKELSQNLGGLSLLRDVAFDSLHQYVHASVAPAIDVPTLTSREMDCLQWMCAGKTAWEIGRILSISEAGVNFHICNLRTKFGVSRRNDVVIKAIRLGLITLPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H329</accession>
    <name>A0A2S9H329_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Histidine kinase</fullName>
            <ecNumber evidence="3">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">S2091_0964</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="3"/>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94343">
        <property type="protein sequence ID" value="PRC94343"/>
        <property type="gene ID" value="S2091_0964"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036641">
        <property type="entry name" value="HPT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013655">
        <property type="entry name" value="PAS_fold_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008207">
        <property type="entry name" value="Sig_transdc_His_kin_Hpt_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01627">
        <property type="entry name" value="Hpt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08447">
        <property type="entry name" value="PAS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13188">
        <property type="entry name" value="PAS_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47226">
        <property type="entry name" value="SSF47226"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50894">
        <property type="entry name" value="HPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 7" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PAC" evidence="10">
        <location>
            <begin position="396"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="10">
        <location>
            <begin position="528"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="8">
        <location>
            <begin position="723"/>
            <end position="944"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="9">
        <location>
            <begin position="959"/>
            <end position="1080"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="9">
        <location>
            <begin position="1105"/>
            <end position="1223"/>
        </location>
    </feature>
    <feature type="domain" description="HPt" evidence="11">
        <location>
            <begin position="1267"/>
            <end position="1365"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="7">
        <location>
            <position position="1012"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="7">
        <location>
            <position position="1156"/>
        </location>
    </feature>
    <feature type="modified residue" description="Phosphohistidine" evidence="6">
        <location>
            <position position="1306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PRC94343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="1452" mass="159753" checksum="6ABC3E33D5A831B0" modified="2018-07-18" version="1">MLMLVAFGAFLTYSHVTETDRINSSERERLHTLTNVVASDIQNNLTTVNHTLEGVIQDFLVGHPVQSSDALLLRLRALESAIPGIRALLVLDAHGLVVTASQPILLGKDLSFRDYFKRAQQQSDSATLYVSAPFQSLKKEPDLVMAVSRVVLSQDGQFTGMVVAALNQDFFSDSFTPVVYAPDVWGFVVHGDGEQLLNYPEKKGIGGTNLNRSGTFFSRHRQSGQVESVVTGTMYTTGERRMMVLQTIQPAALHMDKAIVIGISRELTAIAVPLQHQAAAYSVFFVAISLLCCLALYWMQTRRSRIETLRVEIEQERLDANDRIKLALRGANLALWSVHIPTNTRWFDENCFAIMGIASLSTNEDTDLFRQRIHPDDYAACFSEVGTCINGSKPLLEVTVRMQHSLGHWIWILTRGQAIERDANGRAVMLMGTFMDISVTKTAEQEVVRGRNELQVIFDNMTEGVFVFDNTNTLIRANDAARSIHGLFYQPRSIEEVWSGIDVYLPNGEILPKENWPTRRGFREDFVRNFELEIRRKDTGMAVFVNVNVTPVYGESKELSLLIVTFTNITEQRLTHALRESEARFRTLIEDAPLAIAILRGGHFVYTNPRYNILHGYAPTDDLKDQPWQTMISPESLDQLHEQETLINEDSPIEQMFEAHGLGNNGKLVPVFKTTTRVELVDGPATLIFAQDISAQKRAESLLLEARDAAETANRSKAEFLANMSHEIRSPLNAILGLAYLLEQAHLDLDAHNMVHKIRKSGRMLLGIINDILDVSKIDAGHMVIEQAPFKLGDVVDNIASSMGVILGDKDIQLIIQPPPAGILSLIGDALRLEQILNNLTSNAIKFTHEGRVELCISLQSQNEKHVVLRFCVKDTGVGIPLELQTAVFSAFTQADSSTTRRFGGTGLGLTICRQLVSLMGGEIGLTSTPGQGSEFWFTLPLQLITNADFSSPDMVRVDAMIADSCDIELKAITDIALGLGWQVSALASGEAVLAEIMERKDGELPDVVILDWNIPGMDGLETAHAIRACLADDECPVVIMATAFSLSSLASRPGAELVDAILNKPVTTSALYNATIEAQRRRAVSFGTSHTVAQTTTYGLAGIRLLVVDDSEINRDVAQRILQGEGAIVTLAVDGKDALDWLQAHPDDVDLVLMDVQMPVMDGIEATTRLRLMPQFNDLPIVALTAGAFQSQQEAARAAGMTHFISKPFDVPTTVTLIQRLRRTQNSVNSDTHNINDATPAERANIELPTDLPVIDIAKGLQIWPNLQTYRDYLRRFVKGYGNTINVINASLVNDDRPGAAALVHKLAGVAGSMAMPTTYRLAIEAERVLASEYDATLILGRLDDALKQVIVAIDRFAPAVVMEQLVPASTFTVGDMSSALCAQLDILLAALLKALDTDNPAPVRKILSTLVTLLPAQELSAIRENVHAFDFRAAETATIKLAQQIGITLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3H7</accession>
    <name>A0A2S9H3H7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0524</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94521">
        <property type="protein sequence ID" value="PRC94521"/>
        <property type="gene ID" value="S2091_0524"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="92" mass="10768" checksum="E48D2636F0899ECB" modified="2018-07-18" version="1">MKIKLQQLARQNGQHAAIKAKRVAIILTLPVRDAVSQRWLKMEALRVAKTVEYHLRQANLIGQLIERMDEKIRLQHQYPDRAFKINLPYAPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3R6</accession>
    <name>A0A2S9H3R6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Efflux transporter, RND family, MFP subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_0622</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94619">
        <property type="protein sequence ID" value="PRC94619"/>
        <property type="gene ID" value="S2091_0622"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039562">
        <property type="entry name" value="MFP_biotin_lipoyl_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006143">
        <property type="entry name" value="RND_pump_MFP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13533">
        <property type="entry name" value="Biotin_lipoyl_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01730">
        <property type="entry name" value="RND_mfp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="23"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="domain" description="Biotin_lipoyl_2" evidence="4">
        <location>
            <begin position="92"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="HlyD_D23" evidence="5">
        <location>
            <begin position="141"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="120"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC94619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="422" mass="45534" checksum="AE47B57AF70A475B" modified="2018-07-18" version="1">MIRDTSSQDSVITASQWQKHKRLGLWGAGTAVFIVAAVVMLTAWRSSSQSVNMSRLRIAAVSHGTLVRDASVNGKIIAAISPTLFSSAIGTVTLKVKAGDTVKKGDVLAELESPDITEALKREQSSYEQLEDEVARQKILANKQKLLAQRDADQAEIERISAERAYQRIENAGVIGVVSKNDFLKAQDALKSAEIRSKHAAAAAGLENEDVQLELKSKVSQLDRQKIALGYAQRRVDALQLRAPVDGFIGTLSVSNRTVVAANVPLMTLVDLSQLEVEVEIPETYVADLGLGMNAEISIGDSKVMGKLSSMSPEVANNQVLARIRFDGAQPTGLRQSQRVTARLLIEEKPNVMLVQRGPFLEQLGGRAVYVVNNGIAEKRSIKIGATSVTSVQILEGLKDGDQVVIAGSDAFENANRVSINN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3X9</accession>
    <name>A0A2S9H3X9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Branched-chain amino acid transport protein (AzlD)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0579</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94576">
        <property type="protein sequence ID" value="PRC94576"/>
        <property type="gene ID" value="S2091_0579"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008407">
        <property type="entry name" value="Brnchd-chn_aa_trnsp_AzlD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05437">
        <property type="entry name" value="AzlD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="79" mass="8827" checksum="2CA8FCED6C4667CE" modified="2018-07-18" version="1">MEVNYEIFLIIVGCGIVTLLPRVLPLMLLSKFKFPQWYKDWLSFIPVTIMAALVAQEVIPEDGNVSTAFPAIIASGISW</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H429</accession>
    <name>A0A2S9H429_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0714</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94711">
        <property type="protein sequence ID" value="PRC94711"/>
        <property type="gene ID" value="S2091_0714"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="13"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="304" mass="33955" checksum="6068AB96DB492F66" modified="2018-07-18" version="1">MKRNFNDLMLGSIELFCLAAELSSFTEAATAASVTPAAVSRSVSRLEVRLGIRLFVRTTRQIRLTDAGRIYFDQCRQALSQLIDAERAAGGQQVKPAGLLRISMPTPYAHCRVLPLLKQFRARYPDVLIDVHVSNRNIDFVDEGYDLAIRGRAPADSNLIARKLEDAELVLVAAPSYLKRAGTPKTIDDLQKHECIQFELPSTGKHISWRFLVKGKVVDVATSGGYSCSEDYLGIVTLARDGAGIVQTYRFIVENDIKQGYLVELLPEFGGMSLPFLLIYPHARHMSLRVRVFVDFLLEQLARN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H432</accession>
    <name>A0A2S9H432_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0733</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94730">
        <property type="protein sequence ID" value="PRC94730"/>
        <property type="gene ID" value="S2091_0733"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="75" mass="8534" checksum="3FDD7CB48E3FEFD8" modified="2018-07-18" version="1">MPALLELVVLVLLALLPAVLLPPHPDNASTHIPRPTNVFTTASRRFKFKLFPCFLMKNQSSTKIDYRLVNFNQEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H459</accession>
    <name>A0A2S9H459_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC-type sugar transport systems permease component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_0659</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94656">
        <property type="protein sequence ID" value="PRC94656"/>
        <property type="gene ID" value="S2091_0659"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008643">
        <property type="term" value="P:carbohydrate transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="82"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="115"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="167"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="211"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="269"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="78"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC94656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="307" mass="35293" checksum="550E77D1E58F5DF8" modified="2018-07-18" version="1">MRVKKLEIFPYLLLMPAILMMVVVNLTPIIQGFYMSLLKLNQYTLSQYLDAPFIGLENYRRVIFEEHSPIRAGLGFALRNTLLYTLMVSVLAIVIGLAVAVLLNRDFPGRSIARTLLLLPWIVPSYVVGTLWGFMWQRDVGIINVVLVDWLHLFSERPFWLLGSNSFWAIVIPTVWRAWPVMMLIFLAALQAIPEDQYEAATLDGISKWQQFIHITLPLLKPVIVIQFMFQIIDNIYSYNIVSMMFGNGAGHPGEWADLLMPLLTRQSFSYWLFGQGAAVSFIMMIIMLIFVAAWMRSFKRSMISDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H470</accession>
    <name>A0A2S9H470_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Bacterial Ig-like domain (Group 1)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0788</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the intimin/invasin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94785">
        <property type="protein sequence ID" value="PRC94785"/>
        <property type="gene ID" value="S2091_0788"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003344">
        <property type="entry name" value="Big_1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008964">
        <property type="entry name" value="Invasin/intimin_cell_adhesion"/>
    </dbReference>
    <dbReference type="SMART" id="SM00634">
        <property type="entry name" value="BID_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49373">
        <property type="entry name" value="SSF49373"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51127">
        <property type="entry name" value="BIG1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Big-1" evidence="2">
        <location>
            <begin position="65"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="domain" description="Big-1" evidence="2">
        <location>
            <begin position="168"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="domain" description="Big-1" evidence="2">
        <location>
            <begin position="283"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="domain" description="Big-1" evidence="2">
        <location>
            <begin position="508"/>
            <end position="608"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="878" mass="84787" checksum="E4992E66A948BD27" modified="2018-07-18" version="1">MKLNLTPIFTARYWTFLMSALLLIMISACGGGNGSAGTPLGGSGSGSGGTGGTTPTTNGVITLTLTNAGTASNTIPSNGSLTATANVVNAAGAAVANTLVTFTLSGTTTAVIAPVLTALTNSSGNAVILLQAGTTAGAGTLTASATVVGTTAITGSASFQNLNGTTPGANSVITLALTTAAGTSATTIPPGGSLSATATVTTGGVAVPNALVTFSVSSATGSLPITTALTNSAGIAVVSLQSGTVSGAGTLTASTAVSGNTAPITNSVNYTSGATGPTASPQIAISFASSTGCTANTITTSCPITASATVTDASGNPVANTLVSFSNSLSGVVLAPSAGIVITNSSGVATVTVSAAGLVTSGQAGSAGRVSATTTIAGVTVVAGQNYTLGNTAITLVGVTPASGTANVSAYGTTTIAVQVDSAGAIYTAQPVTVNFASSCAANGKASLPATATTVNGVAQVTYTDNGCGTTDTVTASVAGVAATVTITLKVAAPTAASINFVAVSPTSSSIVLPSTGGVGRTSTATLTFEVVDVNGNPINGAAVNFANLYANANPGAPVIATLNSTSSTTGSNGQVTTTVTAVSVGTLSITASLVSTPSIASTSNTVVVSTGQPTQASFSLSASVFNIEGWSYNGITSTLTTFIADANGNPVVNGTPVVATTNKGSVGNSSGVSAGCTTVNGQCSLTFTSQNPRVVARTAVGVATVQFSSTNNTTLPIAGSLQLYLSGSSPNIYYFNGTNWVLANNNGGVPQALSTNNCSQNVEFVITDENGNPMPATTSIIATTTQTGITIGTLLPGAVPNTPVGGGTQLTLPTTPATTVNGTTVVIPYNLSVSATTGSAPQCLDGGGTQSPFNFSVTTTTPQGVTTLTNFVLKYPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H472</accession>
    <name>A0A2S9H472_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Amino acid/peptide transporter (Peptide:H+ symporter)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_0773</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94770">
        <property type="protein sequence ID" value="PRC94770"/>
        <property type="gene ID" value="S2091_0773"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904680">
        <property type="term" value="F:peptide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015833">
        <property type="term" value="P:peptide transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005279">
        <property type="entry name" value="Dipep/tripep_permease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000109">
        <property type="entry name" value="POT_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11654">
        <property type="entry name" value="PTHR11654"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00854">
        <property type="entry name" value="PTR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00924">
        <property type="entry name" value="yjdL_sub1_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0571">Peptide transport</keyword>
    <keyword evidence="2" id="KW-0653">Protein transport</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="15"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="51"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="81"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="106"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="140"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="169"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="212"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="238"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="268"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="312"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="347"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="381"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="414"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="454"/>
            <end position="476"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC94770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="489" mass="53811" checksum="3591C5A6069ED6D8" modified="2018-07-18" version="1">MSSLKSKLSNIPQGAGALFFIQMFSTLGFAVLYSSLVLYASKHLHFSTAKAAAAMGIFGAFNYGLHLFGGYLGGRFLSNRNLFVGGMVLQVIGCACIAGGSTELFYWGLALFLTGSGLNVTCINMMLTQRFKPEDIRREGAFLWNYAGMNVGFFVGFTVAGYYQLTESYASLFIFATLGNFMAIVLASFNWKSLVDLNTPLLNATPTEYKKRFIAGIAILLGLVPVVWYLLQSEWTENLVKTICLLVAITLLYLTIIHKDKREKNNMWAYLILTLSSLVFWSLYQMAPNGLQLFAVNNVDLVVWGHIVAPQWIQNINTVTIVFGGPLMSALFVRLRAKGWNIDVPKQFSTSLILMGLGFLALPLGILFADDKGMVPFFWLFLSYVLQSIGELLISPVGYAMIGRMAPRQYQGIMMGSWMLITGVASLFAGDFSGMIPEPSAGTPLTTNADYSHLFSQLGWGTVAVGVVLVVLIPFLRKLIKDKEAPEVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4J5</accession>
    <name>A0A2S9H4J5_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ATP-dependent Clp protease adapter protein ClpS</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">clpS</name>
        <name evidence="3" type="ORF">S2091_0082</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Binds to the N-terminal domain of the chaperone ClpA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the ClpS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94887">
        <property type="protein sequence ID" value="PRC94887"/>
        <property type="gene ID" value="S2091_0082"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030163">
        <property type="term" value="P:protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00302">
        <property type="entry name" value="ClpS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022935">
        <property type="entry name" value="ClpS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003769">
        <property type="entry name" value="ClpS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014719">
        <property type="entry name" value="Ribosomal_L7/12_C/ClpS-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33473">
        <property type="entry name" value="PTHR33473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02617">
        <property type="entry name" value="ClpS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54736">
        <property type="entry name" value="SSF54736"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ClpS" evidence="2">
        <location>
            <begin position="19"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="102" mass="11614" checksum="FCDB9169FB6D694F" modified="2018-07-18" version="1">MANKHENSTVIERQTEKLKPPSMYQVVLLNDDYTPMEFVVIVIQEYFNKGRETAMQIMLKVHRDGKGVCGVFPKDIAATKVDLVMAYARQAGHPLQCVMEEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4Q1</accession>
    <name>A0A2S9H4Q1_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Aminopeptidase</fullName>
            <ecNumber evidence="8">3.4.11.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">S2091_0154</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Release of an N-terminal amino acid, Xaa-|-Yaa- from a peptide, amide or arylamide. Xaa is preferably Ala, but may be most amino acids including Pro (slow action). When a terminal hydrophobic residue is followed by a prolyl residue, the two may be released as an intact Xaa-Pro dipeptide.</text>
            <dbReference type="EC" id="3.4.11.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="8">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the peptidase M1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.-" evidence="8"/>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94959">
        <property type="protein sequence ID" value="PRC94959"/>
        <property type="gene ID" value="S2091_0154"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09601">
        <property type="entry name" value="M1_APN-Q_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1730">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045357">
        <property type="entry name" value="Aminopeptidase_N-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042097">
        <property type="entry name" value="Aminopeptidase_N-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024571">
        <property type="entry name" value="ERAP1-like_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034016">
        <property type="entry name" value="M1_APN-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001930">
        <property type="entry name" value="Peptidase_M1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014782">
        <property type="entry name" value="Peptidase_M1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027268">
        <property type="entry name" value="Peptidase_M4/M1_CTD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11838">
        <property type="entry name" value="ERAP1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01433">
        <property type="entry name" value="Peptidase_M1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17900">
        <property type="entry name" value="Peptidase_M1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00756">
        <property type="entry name" value="ALADIPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63737">
        <property type="entry name" value="SSF63737"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 13" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="5 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 8" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="3 8" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <keyword evidence="6 8" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015536664" description="Aminopeptidase" evidence="9">
        <location>
            <begin position="35"/>
            <end position="897"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M1_N" evidence="12">
        <location>
            <begin position="58"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M1" evidence="10">
        <location>
            <begin position="270"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="domain" description="ERAP1_C" evidence="11">
        <location>
            <begin position="564"/>
            <end position="870"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU364040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF11838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF17900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PRC94959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="897" mass="98121" checksum="1174836FF915CDF3" modified="2018-07-18" version="1">MLIIKKPSETGLIFTKLLLCSAVAATLPYQAAFAETSTSLVPYSFTTTPGRLPKNVIPTDYVISITPDAAQHQLTGTETVSLEFTEAVNKIQFNSLNQTLSKVLFDGKPVKSVESDDKAQLTTVILPTNAKVGKHQLTFAFTGKIETDPHGLFVQEYTAPDGTKDMMLSSKFEATDARRMFPCWDEPAFRATYQLNLTAPAAWTAIANMPVASRKVNGTLATTSFERSPKMPTYLVHVSAGNLGMLSGESEGTKLNIVAAKGQEQNGAEALANAKQILADYNAYFGYKFPLPKLDSIAVPGGFQGGMENWGAITYNDQALLLTPSSSKGQHQSVYSIQAHEMAHQWFGDLVTMGWWDELWLNESFASWRAAKETDLRHPDWHWWESQDASKEDAMSADANVHSHPILQHVTNELEATSAFDPSITYNKGQAVLRMIEAYLGPDVFRDGIRQYMKAHAFSNTTSADLWQALSKASGKNVAEIVGGWTTQAGFPLVSVQSNCDANGNRSITLNQQQFLASGNSAGTAHWNIPLQIRTGTSTTAKSVLLTKDGQTEAAGKCEEALSVNADTVGYYRTNYDAATLQANNRHFSTMSNGDRIALLDDQWALVKAGKQNLSGFFALASAMGTDQNLRSWQIITEALGDIEHAERGTPGYDAFVTYARSIIKPLANQLGWENKAGETPGIQRLRRTVLSDLGAWGDADVIAEARARFALFVKDRTAIPVDNQGFILAIVALNASGAEFEQLHALAKSAKNETEMRRYYPVMMLARDPAVASKASEIVLSDEIPKQADGMRLQLALTLSEHNPDLSWSIFTKNYERLIAPYLPEGTTMMASMTPDVFWNSIPLDQVETWIKANAPEEVAPLIARGMEAAHTKLAQKTLLNQATDAFLQSKAVASK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4T7</accession>
    <name>A0A2S9H4T7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">LssY C-terminus</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0172</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94977">
        <property type="protein sequence ID" value="PRC94977"/>
        <property type="gene ID" value="S2091_0172"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025902">
        <property type="entry name" value="LssY-like-C_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14067">
        <property type="entry name" value="LssY_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="domain" description="LssY_C" evidence="2">
        <location>
            <begin position="61"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="242" mass="26922" checksum="8C7807BE5DD289BC" modified="2018-07-18" version="1">MANELTPVHKRSLIRIAVITGVLVLAPAISYFSVAYEFVPMAWRFVERRHPALDSIGTRAFTSAGIPGDPLNVAFVGSEDALHKKMLGAGWYPADPITLRSSLRIARDSLLHKPYPDAPVSDLFVNGQKQSYAFEQAEGGNPSKRHHVRFWRTPDIDALDRPMWIGAATFDSGVGLSHTTGQITHHIAAEVDRERDKLITDLQHSGEIVLRWIEPFQKELEGRNGGGDKFKTDGRLVVFSEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4U0</accession>
    <name>A0A2S9H4U0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative nucleic acid-binding protein contains PIN domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0156</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94961">
        <property type="protein sequence ID" value="PRC94961"/>
        <property type="gene ID" value="S2091_0156"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002716">
        <property type="entry name" value="PIN_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01850">
        <property type="entry name" value="PIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="SSF88723"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PINc" evidence="1">
        <location>
            <begin position="1"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="133" mass="14356" checksum="AEFD3FCC7E62E289" modified="2018-07-18" version="1">MLDTNMASYIIKGNPPEARQRLAALPMKQIVVSVVTQGELLYGLARKGHTTAFGNLIREFLLRVEILPWDEECAIIYGDLRASCAASGVTLGALDMMIAAHAVATKATLVTHDKAFALVSDAVLTVEDWISQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4U8</accession>
    <name>A0A2S9H4U8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0183</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94988">
        <property type="protein sequence ID" value="PRC94988"/>
        <property type="gene ID" value="S2091_0183"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021969">
        <property type="entry name" value="DUF3579"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12112">
        <property type="entry name" value="DUF3579"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="115" mass="12881" checksum="DD05B76F214850A0" modified="2018-07-18" version="1">MVDSTSNNKPPKSEFFILGLTSDGKQFRPSDWSERLSGAMSCFRPDSGRQSHLHYSLFVQPILINGIRSVVVDHALREIEPLAYHFVLDFAKDNDLQIIDACLIPETPAQPAKPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4W4</accession>
    <name>A0A2S9H4W4_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 4">Protein GrpE</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">HSP-70 cofactor</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">grpE</name>
        <name evidence="8" type="ORF">S2091_0111</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 4">Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3 5">Belongs to the GrpE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94916">
        <property type="protein sequence ID" value="PRC94916"/>
        <property type="gene ID" value="S2091_0111"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000774">
        <property type="term" value="F:adenyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042803">
        <property type="term" value="F:protein homodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00446">
        <property type="entry name" value="GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.22.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.20.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01151">
        <property type="entry name" value="GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000740">
        <property type="entry name" value="GrpE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013805">
        <property type="entry name" value="GrpE_coiled_coil"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009012">
        <property type="entry name" value="GrpE_head"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21237">
        <property type="entry name" value="PTHR21237"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01025">
        <property type="entry name" value="GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00773">
        <property type="entry name" value="GRPEPROTEIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51064">
        <property type="entry name" value="SSF51064"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58014">
        <property type="entry name" value="SSF58014"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01071">
        <property type="entry name" value="GRPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4 8" id="KW-0346">Stress response</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="34"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000639"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC94916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="186" mass="20618" checksum="991E0A5CF2D1E3D8" modified="2018-07-18" version="1">MQDQVKQDTQQEAKQNETVNPVQGDAEPVMVAVDSDFEEKLLQTEAKLAELQDAFLRAKADGENIRRRAQDDISKAHKFAVESFAESLIPVKDSLEMALKIETVSVEALREGTEVTLRQLANAFEKNRLLEINPVPGEKLDPAKHQAVSMVPSEQDANTVVEVLQKGYTIADRLLRPALVTVAQAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4Z9</accession>
    <name>A0A2S9H4Z9_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 18">Diacylglycerol kinase</fullName>
            <ecNumber evidence="5 18">2.7.1.107</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">S2091_0257</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="18">Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="18">
            <text>a 1,2-diacyl-sn-glycerol + ATP = a 1,2-diacyl-sn-glycero-3-phosphate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10272"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17815"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58608"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.107"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 18">Cell inner membrane</location>
            <topology evidence="3 18">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 18">Belongs to the bacterial diacylglycerol kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.107" evidence="5 18"/>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95062">
        <property type="protein sequence ID" value="PRC95062"/>
        <property type="gene ID" value="S2091_0257"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004143">
        <property type="term" value="F:diacylglycerol kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006654">
        <property type="term" value="P:phosphatidic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd14264">
        <property type="entry name" value="DAGK_IM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.3610">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000829">
        <property type="entry name" value="DAGK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033718">
        <property type="entry name" value="DAGK_prok"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036945">
        <property type="entry name" value="DAGK_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34299">
        <property type="entry name" value="PTHR34299"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01219">
        <property type="entry name" value="DAGK_prokar"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01069">
        <property type="entry name" value="DAGK_PROKAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14 18" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 18" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="13 18 19" id="KW-0418">Kinase</keyword>
    <keyword evidence="18" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="15" id="KW-0460">Magnesium</keyword>
    <keyword evidence="17 18" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12 18" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 18" id="KW-0808">Transferase</keyword>
    <keyword evidence="10 18" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="16 18" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="42"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="67"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="107"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00017575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="RuleBase" id="RU363065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="PRC95062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="132" mass="14885" checksum="C5D26D0D7CA50744" modified="2018-07-18" version="1">MSEHDPQPISEFKSKSGLKRIFSAFFYSIDGFKSAWKQEHSFRQELVLVTIGIVVALFLPISAYQKLMLIVVLLFILIVELINSAIEAVVDRVSLERHTLSKNAKDFGSAAVFLAVFIAVATWSVVLYERFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H545</accession>
    <name>A0A2S9H545_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Histidine phosphatase superfamily (Branch 2)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0307</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95112">
        <property type="protein sequence ID" value="PRC95112"/>
        <property type="gene ID" value="S2091_0307"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07061">
        <property type="entry name" value="HP_HAP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033379">
        <property type="entry name" value="Acid_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000560">
        <property type="entry name" value="His_Pase_clade-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00328">
        <property type="entry name" value="His_Phos_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="SSF53254"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00616">
        <property type="entry name" value="HIS_ACID_PHOSPHAT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015702569" evidence="1">
        <location>
            <begin position="26"/>
            <end position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC95112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="420" mass="45449" checksum="81D43622C8EC11E0" modified="2018-07-18" version="1">MRFKSKFSSVALFTLLVTFIIPSYAQEAELTLERAVLVMRHGVRPPTKSAKAMAAWSDSSWPDDAAWGAAPGELTPHGAESIRKLGVDLRHFYASAGLLPEQGSISEKTLLWADGADQRTRATAHFLAQGLTTDQTNAPAVAWSANATDPLFDALSAGVCKLDPIAAQKAVLENGPIDTPKTNAALANLQKVMAPLACNKGPGMCLAEPSKLSTSATEVKLLGPLATGATVAEILLLEYENGLPLSQVGWGRVSRDDIASLLLIHEHASNLTRRTPYIALRRADSLVRFILAALSENSVSSTIPKIAEQNRLIVLAGHDTNLSNLAGVFNLNWHLPDQPDVTAPGTAIAFERWRDNKTGQALLRMRLFYQGMEQVRELQGEPLRQIPLMPAACQAKGKHCELADVVQEVMKTLPTDCQRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5A0</accession>
    <name>A0A2S9H5A0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0360</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95165">
        <property type="protein sequence ID" value="PRC95165"/>
        <property type="gene ID" value="S2091_0360"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="3"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC95165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="318" mass="35596" checksum="B68A08BEAD8F6069" modified="2018-07-18" version="1">MKLDPRQLTHLQAVIENGGFGRASEAIHLTQPALTRSIQALERSVGAKVINRQRGGLVLTEVGELLLEHACRLNKAERELQRHISMIQGLEMGELRIGVGMFAAAGLIGPAIGLLNQHHPNIKVRVTVAPYHEMPERVLNGDLDIIVMEKSLLTDRDQFEIETLSPHPMAMVCRDGHPLQSRKKVGLREMLSFPLAAPKMPPALAENFKHNLLKTVPDLAEQARDLATIECDSWRILLDVILHSDAVAMFPIFAIEQELRSGRLHSLPPFDIGIDFRLALAYRGRRDLTSSEARFIELLHQHDKQIFATIRQLMSDSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5A3</accession>
    <name>A0A2S9H5A3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0342</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95147">
        <property type="protein sequence ID" value="PRC95147"/>
        <property type="gene ID" value="S2091_0342"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021675">
        <property type="entry name" value="DUF3261"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11659">
        <property type="entry name" value="DUF3261"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015606168" evidence="1">
        <location>
            <begin position="24"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC95147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="186" mass="20955" checksum="321B088A40B6F505" modified="2018-07-18" version="1">MHIRMMRVWGLNCCLVLLLTACASQPPLPARLDLKLAPAELGESISLQQHLIVERNGRIDDLDAALEVDATQLQLVGIAFGQRVLSLNYDGKQVSSWRHVMLPKQVRAEDILEDIQLTLWPIESIRKALPSGWTIEDNGLRRTLMMGGEVVCIINYSAMPRWSGTVKLENLRYHYSLIIQSVSNNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5B4</accession>
    <name>A0A2S9H5B4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0375</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95180">
        <property type="protein sequence ID" value="PRC95180"/>
        <property type="gene ID" value="S2091_0375"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC95180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="101" mass="11647" checksum="9F0B41B80BE9E06E" modified="2018-07-18" version="1">MTSIDQQHTQQLRPLITHLAVDTIDAYTQARDIVRDFSAIFEVLDHLALTDFSNERIAPILFRAGFCHATERLKFIDERITDAYKTLDDLKTDSSHTFHAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5G2</accession>
    <name>A0A2S9H5G2_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Glutathione-dependent peroxiredoxin</fullName>
            <ecNumber evidence="3">1.11.1.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_0393</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>a hydroperoxide + 2 glutathione = an alcohol + glutathione disulfide + H2O</text>
            <dbReference type="Rhea" id="RHEA:62632"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30879"/>
            <dbReference type="ChEBI" id="CHEBI:35924"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:58297"/>
            <dbReference type="EC" id="1.11.1.27"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the peroxiredoxin family. Prx5 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.27" evidence="3"/>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95198">
        <property type="protein sequence ID" value="PRC95198"/>
        <property type="gene ID" value="S2091_0393"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03013">
        <property type="entry name" value="PRX5_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037944">
        <property type="entry name" value="PRX5-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013740">
        <property type="entry name" value="Redoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10430">
        <property type="entry name" value="PTHR10430"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08534">
        <property type="entry name" value="Redoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0049">Antioxidant</keyword>
    <keyword evidence="2 3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="1 3" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="3" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="4">
        <location>
            <begin position="7"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU366011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC95198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="172" mass="18104" checksum="9D36F3B1A4781740" modified="2018-07-18" version="1">MTTTAQIKIGDKLPNGSLAEYIEVASGACSIGPNTFNVADLTKGKTIAIFGLPGAYTPTCSAQHVPGYVALSAQLKAAGVDEIWCISVNDAFVMGAWGRDQKATDIVRMMGDGNADFSRALGLDADFSKHGMGVRSQRYSMLVVDGVVKQLNVEQGGKFEVSNAETLLAQLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5I5</accession>
    <name>A0A2S9H5I5_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Cell division protein FtsQ</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">ftsQ</name>
        <name evidence="10" type="ORF">S2091_0396</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Part of a complex composed of FtsB, FtsL and FtsQ.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell inner membrane</location>
            <topology evidence="8">Single-pass type II membrane protein</topology>
        </subcellularLocation>
        <text evidence="8">Localizes to the division septum.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the FtsQ/DivIB family. FtsQ subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95201">
        <property type="protein sequence ID" value="PRC95201"/>
        <property type="gene ID" value="S2091_0396"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032153">
        <property type="term" value="C:cell division site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090529">
        <property type="term" value="P:cell septum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043093">
        <property type="term" value="P:FtsZ-dependent cytokinesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11690">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00911">
        <property type="entry name" value="FtsQ_subfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005548">
        <property type="entry name" value="Cell_div_FtsQ/DivIB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026579">
        <property type="entry name" value="FtsQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045335">
        <property type="entry name" value="FtsQ_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034746">
        <property type="entry name" value="POTRA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013685">
        <property type="entry name" value="POTRA_FtsQ_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35851">
        <property type="entry name" value="PTHR35851"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03799">
        <property type="entry name" value="FtsQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08478">
        <property type="entry name" value="POTRA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51779">
        <property type="entry name" value="POTRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3 8 10" id="KW-0132">Cell division</keyword>
    <keyword evidence="2 8" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="1 8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="domain" description="POTRA" evidence="9">
        <location>
            <begin position="37"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC95201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="257" mass="29128" checksum="431E25E91E8292BF" modified="2018-07-18" version="1">MWQDIKLLNATANVLFGACALLLLLSGIWVVMHRPMFTLNVIQVEGQDNTVLKHVNSEIIRSTALPRIKGNFFTTNLDTVRSSFEQVPWVRKASVRREWPDKLIVTLEEHMPLGTWGEDGQLLSVKGEIFTANLAEAEEDTKLLEFSGPVGSEKDVLAHYLEFKEWFKAIELTPLAVAYSKRYAWLIKLDNGVAVQLGREENSAVLKERVSRLLHVYPELTNRLQGKIESVDLRYPNGFALKNLGQELSVVGKKKKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSA3</accession>
    <name>A0A2S9GSA3_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HTH cro/C1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_4698</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000046">
        <property type="protein sequence ID" value="PRC90591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90591">
        <property type="protein sequence ID" value="PRC90591"/>
        <property type="gene ID" value="S2091_4698"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="2">
        <location>
            <begin position="17"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="113"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="117"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC90591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="135" mass="15442" checksum="AF9820EE5A30D4E1" modified="2018-07-18" version="1">MTIANLFILPMSFPERLSSLRKQLNFTQQQMADKIGMHVSQLKRYESGASQPTIDVFRRIALALNVSADMLLFEPDERGPDERLKLQFEAVSKLDDKEREAVETMIAGVLHMHDAKRWTQTPTSTAQPKPQTTKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSG4</accession>
    <name>A0A2S9GSG4_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ribosomal RNA small subunit methyltransferase G</fullName>
            <ecNumber evidence="2">2.1.1.170</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">16S rRNA 7-methylguanosine methyltransferase</fullName>
            <shortName evidence="2">16S rRNA m7G methyltransferase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">rsmG</name>
        <name evidence="3" type="ORF">S2091_4644</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>guanosine(527) in 16S rRNA + S-adenosyl-L-methionine = N(7)-methylguanosine(527) in 16S rRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42732"/>
            <dbReference type="Rhea" id="RHEA-COMP:10209"/>
            <dbReference type="Rhea" id="RHEA-COMP:10210"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74269"/>
            <dbReference type="ChEBI" id="CHEBI:74480"/>
            <dbReference type="EC" id="2.1.1.170"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.170" evidence="2"/>
    <dbReference type="EMBL" id="PUGF01000041">
        <property type="protein sequence ID" value="PRC90636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90636">
        <property type="protein sequence ID" value="PRC90636"/>
        <property type="gene ID" value="S2091_4644"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070043">
        <property type="term" value="F:rRNA (guanine-N7-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00074">
        <property type="entry name" value="16SrRNA_methyltr_G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003682">
        <property type="entry name" value="rRNA_ssu_MeTfrase_G"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31760">
        <property type="entry name" value="PTHR31760"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02527">
        <property type="entry name" value="GidB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003078">
        <property type="entry name" value="GidB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00138">
        <property type="entry name" value="rsmG_gidB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="2" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 3" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="2">
        <location>
            <begin position="134"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="83"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="88"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="149"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC90636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="215" mass="23715" checksum="187B06CEEE0DE43F" modified="2018-07-18" version="1">MLGLQEQVECRKLLEEGVVALQLNLDVEQCNKLMSYLNLLSKWNAVYNLTSVRNPREMVKQHLLDSLSAVSVFNHATNILDVGSGGGLPGIVLAIVYPDIKVALIDTVNKKTAFLKQVKAELDLKNVTVHTGRVEQLTAVELFDVITSRAFSELANFVNWAGHLLAPEGSMIALKGHLPEHEIEVLPAGWQINKVQAVSVPGLDAQRHLLWLVRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSG9</accession>
    <name>A0A2S9GSG9_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">ATP synthase gamma chain</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">ATP synthase F1 sector gamma subunit</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">F-ATPase gamma subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">atpG</name>
        <name evidence="10" type="ORF">S2091_4653</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 9">Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell membrane</location>
            <topology evidence="9">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the ATPase gamma chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000041">
        <property type="protein sequence ID" value="PRC90645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90645">
        <property type="protein sequence ID" value="PRC90645"/>
        <property type="gene ID" value="S2091_4653"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045261">
        <property type="term" value="C:proton-transporting ATP synthase complex, catalytic core F(1)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042777">
        <property type="term" value="P:proton motive force-driven plasma membrane ATP synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd12151">
        <property type="entry name" value="F1-ATPase_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00815">
        <property type="entry name" value="ATP_synth_gamma_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035968">
        <property type="entry name" value="ATP_synth_F1_ATPase_gsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000131">
        <property type="entry name" value="ATP_synth_F1_gsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023632">
        <property type="entry name" value="ATP_synth_F1_gsu_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11693">
        <property type="entry name" value="PTHR11693"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00231">
        <property type="entry name" value="ATP-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00126">
        <property type="entry name" value="ATPASEGAMMA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52943">
        <property type="entry name" value="SSF52943"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01146">
        <property type="entry name" value="ATPsyn_F1gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00153">
        <property type="entry name" value="ATPASE_GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 9" id="KW-0139">CF(1)</keyword>
    <keyword evidence="4 9" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="5 9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC90645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="289" mass="31600" checksum="20FE1F34177BCB0F" modified="2018-07-18" version="1">MAVGKEIRGKIKSVENTKKITKAMEMVAASKMRKAQDRMRAARPYSEKIRVIAANLSQANPEYTHPFLITQNQSKTVGLIVVTTDKGLCGGLNTNVLRLVTNKLREVEGQGCKIETVAIGNKGLGFLNRIGAKVSAQVVQLGDTPHLDKLIGSVKVLLDAYQDGKLDAVYLCYTKFINTMKQEPKVEQLLPLTADKLEVKAGDHSWDYLYEPDAQTVIDELLVRYVEAQIYQGVAENMASEQSARMVAMKSASDNAGSVIGELKLIYNKTRQAAITKELSEIVAGAAAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSP3</accession>
    <name>A0A2S9GSP3_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF4236 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4556</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000037">
        <property type="protein sequence ID" value="PRC90730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90730">
        <property type="protein sequence ID" value="PRC90730"/>
        <property type="gene ID" value="S2091_4556"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025330">
        <property type="entry name" value="DUF4236"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14020">
        <property type="entry name" value="DUF4236"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4236" evidence="1">
        <location>
            <begin position="7"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="364" mass="40235" checksum="EC7845D3C7C0EE3F" modified="2018-07-18" version="1">MDFIVGFYIRKSVSVGPFRFNLSKSGIGVSTGIKGLRVGTGPRGNYITVGKSGLYYRATLNGPKITPGGTSNGANPISPTDQSKIIDQMVAIESGPLSSMQDETSFSLINELNTKEKRPNYWKWTLGAGLIGLWFLPPNTPQWLTVLSVLILIGCTSYIAIRDVVAKSVVLCYKLDPNNETAYQCLHDAFLHISECSKKWRINSKGAVRDSKYHAGAGTLVSRKDATFSKGLPPRVKCNLEVPIVKADSISIYFMPDRLLVYSDNEIGAVNYKDLVFNAAAKRFIEEDSVPKDAEVIDHTWKYVNKKGGPDKRFKDNKQIPVVLYEELHFSSSSGLNELFQISKHSIANKLTTALKNMDESIAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSQ0</accession>
    <name>A0A2S9GSQ0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4575</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000037">
        <property type="protein sequence ID" value="PRC90749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90749">
        <property type="protein sequence ID" value="PRC90749"/>
        <property type="gene ID" value="S2091_4575"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC90749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="42" mass="4761" checksum="FDE74AD914824F24" modified="2018-07-18" version="1">MNDGAILFPSSTWCWGALPERVRKKARVKAISTISIYIFEGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GT02</accession>
    <name>A0A2S9GT02_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4498</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000035">
        <property type="protein sequence ID" value="PRC90835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90835">
        <property type="protein sequence ID" value="PRC90835"/>
        <property type="gene ID" value="S2091_4498"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC90835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="257" mass="29064" checksum="DB160D1AA2985F9C" modified="2018-07-18" version="1">MKISIKNLLIAAFIILSLLMLGKYLHISLLEKNKLAFHRDESNYHSAPVIKLIRSKEDHVFYDADVGGVILHIPTNDPSKYFSTSGFIAFWYPDMTLSAWGDTEIRPDNVPDTKNRFRVFISSLAHNVESAPKGQVFIKPSELLEIASKRNNQIPKLNKTQFDELLSFTFEDSEKTKAIQKLSDENYSHFGADYIATENAPYEAYVSCGGPIDRGGCTGDVYIKKLGIQYHFIANFGAERISDLIRDTNLMIASWTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GT03</accession>
    <name>A0A2S9GT03_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF2807 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_4428</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000034">
        <property type="protein sequence ID" value="PRC90847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90847">
        <property type="protein sequence ID" value="PRC90847"/>
        <property type="gene ID" value="S2091_4428"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021255">
        <property type="entry name" value="DUF2807"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10988">
        <property type="entry name" value="DUF2807"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015573792" description="DUF2807 domain-containing protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="domain" description="DUF2807" evidence="2">
        <location>
            <begin position="26"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC90847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="206" mass="21667" checksum="891225DB24E42DEB" modified="2018-07-18" version="1">MRRLVILSLLFLCSFANADQTYQFPAFNAVKSEGVFDIVITAGSAQSVVATGSDAAIKKLSLSVVDGQLLITSPDEKHGSIFSTTTKVTITVPALRLFKGKGVSSVVLKNIDGDRIDIGYEGVGNLEASGKIKWLRLKANGVGDVDTKKLLAENADVDFDGVGSVEMYASNHLNVVAHGVGSVTYYGNPHSIDKSIDGIGGFSAGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GT05</accession>
    <name>A0A2S9GT05_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 7">Outer-membrane lipoprotein carrier protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">lolA</name>
        <name evidence="8" type="ORF">S2091_4430</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 7">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the LolA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000034">
        <property type="protein sequence ID" value="PRC90849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90849">
        <property type="protein sequence ID" value="PRC90849"/>
        <property type="gene ID" value="S2091_4430"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044874">
        <property type="term" value="P:lipoprotein localization to outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042953">
        <property type="term" value="P:lipoprotein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16325">
        <property type="entry name" value="LolA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00240">
        <property type="entry name" value="LolA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029046">
        <property type="entry name" value="LolA/LolB/LppX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004564">
        <property type="entry name" value="OM_lipoprot_carrier_LolA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018323">
        <property type="entry name" value="OM_lipoprot_carrier_LolA_Pbac"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35869">
        <property type="entry name" value="PTHR35869"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03548">
        <property type="entry name" value="LolA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89392">
        <property type="entry name" value="SSF89392"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00547">
        <property type="entry name" value="lolA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0143">Chaperone</keyword>
    <keyword evidence="8" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="6 7" id="KW-0574">Periplasm</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0732">Signal</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015794603" description="Outer-membrane lipoprotein carrier protein" evidence="7">
        <location>
            <begin position="30"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC90849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="220" mass="24224" checksum="028E46FB4BCDDCA7" modified="2018-07-18" version="1" precursor="true">MTTVITTVLKKFSISIAMSSVLLAGAAQAGGLDQFKAFVSSTHSAKGDFIQRQIKVVKGEVKLSNQSSGTFMFARPGKFIWLYQKPYDQLLQADGEKLYMYDKDLNQVTVKLLGTALSSSPAAILFGSNDLEKNFTLKDVGQKDGMDWLQATPKDKDSTFALISIGMQDGVPREMDLRDTFNQTTVILLQNLEKNPVLKPDQFKFTAPAGADVFNSDVKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GT33</accession>
    <name>A0A2S9GT33_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Replication-associated recombination protein A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_4429</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000034">
        <property type="protein sequence ID" value="PRC90848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90848">
        <property type="protein sequence ID" value="PRC90848"/>
        <property type="gene ID" value="S2091_4429"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032423">
        <property type="entry name" value="AAA_assoc_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008921">
        <property type="entry name" value="DNA_pol3_clamp-load_cplx_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021886">
        <property type="entry name" value="MgsA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16193">
        <property type="entry name" value="AAA_assoc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12002">
        <property type="entry name" value="MgsA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48019">
        <property type="entry name" value="SSF48019"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0347">Helicase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="4">
        <location>
            <begin position="46"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008959"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC90848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="436" mass="47716" checksum="5991764256BAEF1D" modified="2018-07-18" version="1">MDDLFKVAPTPPLAEALRPQNLDQVIGQSHLLGAGKPLRLAFESGRPHSMILWGPPGVGKTTLARLTANAFACEFIALSAVFSGVKDIRAAMEQAEQYLAQGKHTILFVDEIHRFNKAQQDALLPYAESGLVTFIGATTENPSFEVNSALLSRAQVYVLQSLTEDELKLLVTRAQSQVLAHLQFDPAAIDTLVGYADGDARRLLNLLEQTSSAAAGVGTTEITPEFIQNALTLNARRFDKGGDNFYDQISALHKSVRGSNPDAALYWLCRMLDGGADAKYLSRRIVRMAWEDIGIADPRAMQIANDAATTYERLGSPEGELALGQAVIYLAIAAKSNAGYNAFNQAMEFIKQDKSREVPVHLRNAPTKLMKELGYGHAYRYAHDEPEAYAAGETYLPDGIPDPHWYEPVPRGLEIKIADKLAHLRSLDAAAKKSKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTA0</accession>
    <name>A0A2S9GTA0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_4327</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000032">
        <property type="protein sequence ID" value="PRC90926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90926">
        <property type="protein sequence ID" value="PRC90926"/>
        <property type="gene ID" value="S2091_4327"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000485">
        <property type="entry name" value="AsnC-type_HTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019888">
        <property type="entry name" value="Tscrpt_reg_AsnC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019887">
        <property type="entry name" value="Tscrpt_reg_AsnC/Lrp_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01037">
        <property type="entry name" value="AsnC_trans_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13404">
        <property type="entry name" value="HTH_AsnC-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00033">
        <property type="entry name" value="HTHASNC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00344">
        <property type="entry name" value="HTH_ASNC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50956">
        <property type="entry name" value="HTH_ASNC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH asnC-type" evidence="4">
        <location>
            <begin position="2"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC90926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="149" mass="17132" checksum="A2379089315BEB50" modified="2018-07-18" version="1">MIDKIDREIIEFLRKDARISYKDLGEKVFLSANAVAERMRRLEQSLVIQGYQVKVNLQALELPLIAIIDVKLALGITALEFETRLQRVTGIIEAILLTGSFDYMLRVACHDQDDLVRLTEELRAKCGVQDSHTRLLLRSMNLENRLAHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTD0</accession>
    <name>A0A2S9GTD0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acetyltransferase (GNAT) domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4362</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000032">
        <property type="protein sequence ID" value="PRC90961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90961">
        <property type="protein sequence ID" value="PRC90961"/>
        <property type="gene ID" value="S2091_4362"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038740">
        <property type="entry name" value="BioF2-like_GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13480">
        <property type="entry name" value="Acetyltransf_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Acetyltransf_6" evidence="1">
        <location>
            <begin position="178"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="360" mass="40423" checksum="80B6E1F836CD9904" modified="2018-07-18" version="1">MLSSGLNSGLKDGLNSGLNSGLSSRVVTPADLTELEITAWNALSANIAHLSSPFLSFQYTSAVAESGVNVKVCVISQDGQLRGFLPYQFQNRTSEWLKSAEPVGRQMTDYFGLIASEDLRITPATLLSLANLNQITFSHLDESQLAYGLTGELPRPGLRIPCDKIFNGNEVDCPISQKHMREMTRREKHLKEDFGPLEFTFDLIENRTEHLHNLIRQKRAQYKRTNVPDVLAQAWKIDLLERLLFTKSSSCRGVLSHLQAGDQWVASHFGIMGNGVLQYWLPVYNPEMAKYGPGRLLLDNICKATTLHNIHTIDRGEGVTPSKKEILSDEHYFYRGVWHNNSLPTLVARGFQSVLWRLGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTH9</accession>
    <name>A0A2S9GTH9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4217</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000030">
        <property type="protein sequence ID" value="PRC91029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91029">
        <property type="protein sequence ID" value="PRC91029"/>
        <property type="gene ID" value="S2091_4217"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="111"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="134" mass="15776" checksum="4C45E610048117E4" modified="2018-07-18" version="1">MRFPNLRYGNNFELQYYCQGKSIKVIAKRLRRTERTISDWLNCKKKMPWWVCEVLRLQDKEHEEMMRQMFWATHKTRAKLGVVSTDAKIIPFIKKEKKELTEEEKLFTLNREPLSAPAPGGQAAASHIPKAKVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTK6</accession>
    <name>A0A2S9GTK6_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA helicase</fullName>
            <ecNumber evidence="3">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">S2091_4322</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O = ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the helicase family. RecQ subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="3"/>
    <dbReference type="EMBL" id="PUGF01000031">
        <property type="protein sequence ID" value="PRC91026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91026">
        <property type="protein sequence ID" value="PRC91026"/>
        <property type="gene ID" value="S2091_4322"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043138">
        <property type="term" value="F:3'-5' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009432">
        <property type="term" value="P:SOS response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004589">
        <property type="entry name" value="DNA_helicase_ATP-dep_RecQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006293">
        <property type="entry name" value="DNA_helicase_ATP-dep_RecQ_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010997">
        <property type="entry name" value="HRDC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002121">
        <property type="entry name" value="HRDC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044876">
        <property type="entry name" value="HRDC_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032284">
        <property type="entry name" value="RecQ_Zn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018982">
        <property type="entry name" value="RQC_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00570">
        <property type="entry name" value="HRDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16124">
        <property type="entry name" value="RecQ_Zn_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09382">
        <property type="entry name" value="RQC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00341">
        <property type="entry name" value="HRDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00956">
        <property type="entry name" value="RQC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47819">
        <property type="entry name" value="SSF47819"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01389">
        <property type="entry name" value="recQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00614">
        <property type="entry name" value="recQ_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50967">
        <property type="entry name" value="HRDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6 13" id="KW-0347">Helicase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="11">
        <location>
            <begin position="26"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="12">
        <location>
            <begin position="215"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="domain" description="HRDC" evidence="10">
        <location>
            <begin position="533"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="503"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="505"/>
            <end position="525"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PRC91026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="607" mass="67880" checksum="3706F26A9B418DB8" modified="2018-07-18" version="1">MKQAALALLQSVFGYPAFRGSQAEIIDHVVGGGDALVLMPTGGGKSLCYQLPAMLRNGVGIVVSPLIALMQDQVDALAEVGVRAAFINSTQTFQQALAIEQKMRKGELDLVYVAPERLLTQRCLELLEVCPISLFAIDEAHCVSQWGHDFRPEYIKLSVLHERFPNIPRIALTATADQATRAEIISRLQLENALQFVSSFDRPNIRYRIVEKASGRQQLLDFLQAEHVQDAGIVYCLSRKKVEETAEFLNQHGITALPYHAGLDLKIRTQNQARFLREESIVMVATIAFGMGIDKPDVRFVAHLDLPKSIEGYYQETGRAGRDGGAANAWMAYGLQDVVQQRRMIDESEADENYKRLQSSKLDAMLALCETIHCRRRHLLSYFDQNDSGANPQCGNCDVCINPPIAFDASVVTQQLLSAIYRVDQRFAAGHVIDVLRGMDSERIQQWRHNQLSTYGIGSERSEAEWRAILRQAIAQGYVSVDYESYNSLKLTETARAVLKGEQSVQMRRYEKPQKASKQKRSTSKGYNETDLSPEGQQVFEKLRSWRMETARLHNVPAYVIFHDSTLRDIAKANPSSLADLRGVSGVGEKKLATYGEQIVELVTALG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTP4</accession>
    <name>A0A2S9GTP4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Antibiotic biosynthesis monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4254</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000030">
        <property type="protein sequence ID" value="PRC91066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91066">
        <property type="protein sequence ID" value="PRC91066"/>
        <property type="gene ID" value="S2091_4254"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007138">
        <property type="entry name" value="ABM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03992">
        <property type="entry name" value="ABM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51725">
        <property type="entry name" value="ABM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABM" evidence="1">
        <location>
            <begin position="2"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="224" mass="25160" checksum="7D912BDD4868F199" modified="2018-07-18" version="1">MFAVIFVVHPKDGRKDEYLGLAKHLKPLLEGTDGFIDNERFESKRTEGDVLSLSTWRDEKAVVRWRTQGEHHQVQEKGRFDVFKDYHLRVGEVTADSHPPEGGTVDEKRFDETVIGEAKVCTITEVIPAKGASLGGLGKLLPAHLGLDLSSAGLVDHVVFQGITIPDKYLLLVDWKDAGAAHAWTPKSFAGVSMLRHRHVRVIRMYGMQDRREAPQYYSDAKTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTZ2</accession>
    <name>A0A2S9GTZ2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">HpnC: squalene synthase HpnC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000027">
        <property type="protein sequence ID" value="PRC91205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91205">
        <property type="protein sequence ID" value="PRC91205"/>
        <property type="gene ID" value="S2091_4100"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004311">
        <property type="term" value="F:farnesyltranstransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00683">
        <property type="entry name" value="Trans_IPPS_HH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017827">
        <property type="entry name" value="HSQ_synthase_HpnC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002060">
        <property type="entry name" value="Squ/phyt_synthse"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044843">
        <property type="entry name" value="Trans_IPPS_bact-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033904">
        <property type="entry name" value="Trans_IPPS_HH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31480:SF17">
        <property type="entry name" value="PTHR31480:SF17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00494">
        <property type="entry name" value="SQS_PSY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01212">
        <property type="entry name" value="Phytoene_synthase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="SSF48576"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03464">
        <property type="entry name" value="HpnC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="269" mass="30751" checksum="6D508FBB54955062" modified="2018-07-18" version="1">MAVNHYENFPVASFLLPARLRPAVRALYTFARSADDIADEGDANDEQRIAGLNSYAAQLAQIKRGDTPDDAQFQVLQQTIAQYQLPIQPLYQLLSAFKQDVVKKRYANYAELLDYCDRSANPVGNLILHLYGAATPQNLHDSDAICSALQLINFWQDVAIDWQKQRIYIPLDDMQRFGVSEQTIGEQICDPAWRALMQFEVQRTRELMLSGSQLACRLPGRIGLELRAVVQGGLRILEKIELKQENVFQDRPKLNKWDSLVIAWRVIWM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GU02</accession>
    <name>A0A2S9GU02_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Potassium-transporting ATPase ATP-binding subunit</fullName>
            <ecNumber evidence="12">7.2.2.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">ATP phosphohydrolase [potassium-transporting] B chain</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">Potassium-binding and translocating subunit B</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">Potassium-translocating ATPase B chain</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">kdpB</name>
        <name evidence="13" type="ORF">S2091_4076</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>ATP + H2O + K(+)(out) = ADP + H(+) + K(+)(in) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:16777"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="7.2.2.6"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="12">The system is composed of three essential subunits: KdpA, KdpB and KdpC.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Cell membrane</location>
            <topology evidence="12">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.2.2.6" evidence="12"/>
    <dbReference type="EMBL" id="PUGF01000027">
        <property type="protein sequence ID" value="PRC91181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91181">
        <property type="protein sequence ID" value="PRC91181"/>
        <property type="gene ID" value="S2091_4076"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008556">
        <property type="term" value="F:P-type potassium transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02078">
        <property type="entry name" value="P-type_ATPase_K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00285">
        <property type="entry name" value="KdpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006391">
        <property type="entry name" value="P-type_ATPase_bsu_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43743">
        <property type="entry name" value="PTHR43743"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="SSF81653"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="SSF81660"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="SSF81665"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01497">
        <property type="entry name" value="kdpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 12" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10 12" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 12" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7 12" id="KW-0630">Potassium</keyword>
    <keyword evidence="3 12" id="KW-0633">Potassium transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 12" id="KW-1278">Translocase</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1 12" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="35"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="62"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="220"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="257"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="591"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="632"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="672"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="active site" description="4-aspartylphosphate intermediate" evidence="12">
        <location>
            <position position="314"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="351"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="355"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="384"/>
            <end position="391"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="411"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="534"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="538"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PRC91181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="698" mass="73785" checksum="0135AA7DFBB768B8" modified="2018-07-18" version="1">MTHKINQSLLNPDILKVALVDAFRKLSPRTQIKNPVMFVVFIGSLLTTGLAFQAVFGKGEAPANFIIAIALWLWFTLLFANFAEALAEGRSKAQAESLRGAKQDVKAKKLQQPKYGSTQLLVNGSTLIKGDVVLVEAHDVIPADGEVIEGAASVDESAITGESAPVIRESGGDFSSVTGGTRVLSDWIVVRVSVNPGEAFLDRMIAMVEGAKRQKTPNEIALTILLVALTIIFLLATVTLLPFSLFSVTAAGAGSPITITVLVALLVCLIPTTIGGLLSSVGIAGMSRMMQANVIATSGRAVEAAGDVDVLLLDKTGTITLGNRQASTFHPATGVTAEQLADAAQLSSLADETPEGRSIVILAKQKYQLRERNIQALGATFIPFTAQTRMSGVDLDESHSGNASEKRHIRKGSVEAIRQYVTNLGHAFPKNVSDLVEQVAKKGSTPLVVVDGSKVMGVIELKDIVKGGIKERFAELRKMGIKTIMITGDNHLTAAAIAAEAGVDDFLAEATPEDKLKLIRSHQAEGKLVAMTGDGTNDAPALAQADVAVAMNTGTQAAKEAGNMVDLDSNPTKLIEIVEIGKQMLMTRGSLTTFSIANDVAKYFAIIPAAFASTYPQLNTLNVMHLTTPASAILSAVIFNALIIVCLIPLALKGLKYRALGAAILLRRNLLIYGLGGLIVPFIGIKFIDVVLTILGLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GU09</accession>
    <name>A0A2S9GU09_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4147</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000028">
        <property type="protein sequence ID" value="PRC91146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91146">
        <property type="protein sequence ID" value="PRC91146"/>
        <property type="gene ID" value="S2091_4147"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002686">
        <property type="entry name" value="Transposase_17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036515">
        <property type="entry name" value="Transposase_17_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01797">
        <property type="entry name" value="Y1_Tnp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01321">
        <property type="entry name" value="Y1_Tnp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143422">
        <property type="entry name" value="SSF143422"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Y1_Tnp" evidence="1">
        <location>
            <begin position="9"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="175" mass="20893" checksum="93A97C41EE6A1BE0" modified="2018-07-18" version="1">MRIYTRSRIPGATYFFTVNLAERQGNDLLVKHIDALREAFRVTKKTHPFVIEAMVVLPDHLHCLWRLPPDDSDYPKRWRLIKAHFSQMLACGEFISASRKKKGERGIWQRRYWEHVIRDERDLHNHLDYIHYNPVKHGHVLRAIDWPYSSFHIYVVRGHYPADWAAPSNLDRRLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GU50</accession>
    <name>A0A2S9GU50_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">2Fe-2S ferredoxin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_4023</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>2Fe-2S cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49601"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the adrenodoxin/putidaredoxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000026">
        <property type="protein sequence ID" value="PRC91238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91238">
        <property type="protein sequence ID" value="PRC91238"/>
        <property type="gene ID" value="S2091_4023"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140647">
        <property type="term" value="P:P450-containing electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00207">
        <property type="entry name" value="fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001055">
        <property type="entry name" value="Adrenodoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018298">
        <property type="entry name" value="Adrenodoxin_Fe-S_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011536">
        <property type="entry name" value="Fdx_isc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23426">
        <property type="entry name" value="PTHR23426"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00111">
        <property type="entry name" value="Fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00355">
        <property type="entry name" value="ADRENODOXIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="SSF54292"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02007">
        <property type="entry name" value="fdx_isc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00814">
        <property type="entry name" value="ADX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="4">
        <location>
            <begin position="2"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC91238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="112" mass="12290" checksum="532CBF107F40C284" modified="2018-07-18" version="1">MSQIIVLPHQQLCPEGAVLEAEEGASLCEVLIDNDIAIEHACEMSCACTTCHVIVREGFNSLNPSTDNEEDLLDAAWGLEATSRLSCQVKISSQNIVIEIPKYTINHARENH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUC2</accession>
    <name>A0A2S9GUC2_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Inner membrane-spanning protein YciB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">yciB</name>
        <name evidence="2" type="ORF">S2091_3975</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the YciB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000025">
        <property type="protein sequence ID" value="PRC91304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91304">
        <property type="protein sequence ID" value="PRC91304"/>
        <property type="gene ID" value="S2091_3975"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00189">
        <property type="entry name" value="YciB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006008">
        <property type="entry name" value="YciB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36917">
        <property type="entry name" value="PTHR36917"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04279">
        <property type="entry name" value="IspA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="78"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="109"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="151"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="183"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="212" mass="24216" checksum="9A3E3CCBC2D03EA5" modified="2018-07-18" version="1">MKILFDLFPVILFFVMFKWGEGHASAAQSFLQTYFGNLISGGVPSQALAPIILATAVTIVATVLQIAYLLVRRKKVDGMLWISFLIVSVFGGLTIYFHNETFIKWKPTMLYWSYAVALIVSQFALHKNLTRTFLSKLEDDLVIPETVWSKLNYVWIAFFIAMGGLNLLIAYNFSTDIWVNFKLFGSMGFMFVFLLLQIIFLSRYSKPSEESL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUL6</accession>
    <name>A0A2S9GUL6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Bacterioferritin (Cytochrome b1)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_3825</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Oligomer of 24 subunits, arranged as 12 dimers, that are packed together to form an approximately spherical molecule with a central cavity, in which large amounts of iron can be deposited.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterioferritin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000023">
        <property type="protein sequence ID" value="PRC91410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91410">
        <property type="protein sequence ID" value="PRC91410"/>
        <property type="gene ID" value="S2091_3825"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008199">
        <property type="term" value="F:ferric iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006879">
        <property type="term" value="P:cellular iron ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006826">
        <property type="term" value="P:iron ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002024">
        <property type="entry name" value="Bacterioferritin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014490">
        <property type="entry name" value="Dps-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012347">
        <property type="entry name" value="Ferritin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009040">
        <property type="entry name" value="Ferritin-like_diiron"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008331">
        <property type="entry name" value="Ferritin_DPS_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00210">
        <property type="entry name" value="Ferritin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018063">
        <property type="entry name" value="Ferrtn_UCP018063"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00601">
        <property type="entry name" value="BACFERRITIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="SSF47240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50905">
        <property type="entry name" value="FERRITIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0349">Heme</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ferritin-like diiron" evidence="5">
        <location>
            <begin position="34"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="51"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="87"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="134"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="166"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="169"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011713"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR018063-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC91410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="178" mass="19944" checksum="F33F8447CE709636" modified="2018-07-18" version="1">MIKAKNELKKSIDIDAIRSAAKHLDDGAVTVGYQADRKKIIAMLNNALATELVCVLRYKRHYYTAIGLQNGPIKAEFLQHAMEEQGHANLLAERIVQLNGKPDFNPATLVNRSHAEYDDSASIKDMIKANLIAERVAIEAYRQMIEQIGEKDPTTSHMLVGIMAKEEEHADDMRDLMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUP2</accession>
    <name>A0A2S9GUP2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3867</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000023">
        <property type="protein sequence ID" value="PRC91452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91452">
        <property type="protein sequence ID" value="PRC91452"/>
        <property type="gene ID" value="S2091_3867"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="67" mass="7019" checksum="AB0AAA09D6906BEB" modified="2018-07-18" version="1">MSNTNNASSLHKQAALDHETAAKHHQKASECHDQNKPSDAMDSAKSAMASCNTAKKSSDTACASSTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GV24</accession>
    <name>A0A2S9GV24_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fructose-26-bisphosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3685</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000021">
        <property type="protein sequence ID" value="PRC91569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91569">
        <property type="protein sequence ID" value="PRC91569"/>
        <property type="gene ID" value="S2091_3685"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001345">
        <property type="entry name" value="PG/BPGM_mutase_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="SSF53254"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00175">
        <property type="entry name" value="PG_MUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0312">Gluconeogenesis</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="220" mass="24762" checksum="7862EEB4ECC6C64A" modified="2018-07-18" version="1">MIELLLIRHGETAWNAERRLQGHLNIPLNDAGLQQAQALALALKNESLDAIICSDLQRAMQTAQAIAQYQNQQCIIEPAWRERCFGGFEGELISQIEQRFPAEYAAWRAYEIDMQFPANAQGEFNGESIRQFHTRIEQVLLELSQRFQHGKIVVVAHGGVLECAYRIAHQLALDAPRQVSMLNASINRFELSSDQDSVKLKMLQGGDVAHLELALDELNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GV48</accession>
    <name>A0A2S9GV48_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">3-hydroxybutyrate dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000021">
        <property type="protein sequence ID" value="PRC91584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91584">
        <property type="protein sequence ID" value="PRC91584"/>
        <property type="gene ID" value="S2091_3700"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003858">
        <property type="term" value="F:3-hydroxybutyrate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011294">
        <property type="entry name" value="3-OHbutyrate_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01963">
        <property type="entry name" value="PHB_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="260" mass="27095" checksum="F48D0A94CE304DEC" modified="2018-07-18" version="1">MLLKDKVAIITGAASGIGKEIAFEYAKQGAKVVIADLVLDAAQATAAEIVAAGGVAMAVAMNVIDEAQVDKGVADVVAAYGGVDVLISNAGIQIISPIVELSMDSWKKLLAIHLDGAFLTTRACMRAMIKTGRGGSIIYMGSVHSHEASPLKAPYVTAKHGLIGLSKVVAKEGAKDNIRANVICPGFVRTPLVDKQIPEQAKSLGISEADVIKNVMLKETVDGEFTTVQDVAQTAIFLAAFGSNALTGQSITVSHGWHMQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GV72</accession>
    <name>A0A2S9GV72_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, AbrB family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3714</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000021">
        <property type="protein sequence ID" value="PRC91598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91598">
        <property type="protein sequence ID" value="PRC91598"/>
        <property type="gene ID" value="S2091_3714"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007159">
        <property type="entry name" value="SpoVT-AbrB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037914">
        <property type="entry name" value="SpoVT-AbrB_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04014">
        <property type="entry name" value="MazE_antitoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00966">
        <property type="entry name" value="SpoVT_AbrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89447">
        <property type="entry name" value="SSF89447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01439">
        <property type="entry name" value="lp_hng_hel_AbrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51740">
        <property type="entry name" value="SPOVT_ABRB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SpoVT-AbrB" evidence="2">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51740"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="80" mass="8442" checksum="314A783E7A9AAFA1" modified="2018-07-18" version="1">MTTATMTTKGQITIPAPIRAALGLEAGSRIEFIEIQKGQFAIIPATSPVLALKGMLHMPEKPITIEAMNQAIAAQAAKAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GV90</accession>
    <name>A0A2S9GV90_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Endolytic murein transglycosylase</fullName>
            <ecNumber evidence="7">4.2.2.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Peptidoglycan polymerization terminase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">mltG</name>
        <name evidence="8" type="ORF">S2091_3583</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell inner membrane</location>
            <topology evidence="7">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the transglycosylase MltG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.2.-" evidence="7"/>
    <dbReference type="EMBL" id="PUGF01000020">
        <property type="protein sequence ID" value="PRC91645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91645">
        <property type="protein sequence ID" value="PRC91645"/>
        <property type="gene ID" value="S2091_3583"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008932">
        <property type="term" value="F:lytic endotransglycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd08010">
        <property type="entry name" value="MltG_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02065">
        <property type="entry name" value="MltG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003770">
        <property type="entry name" value="MLTG-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30518">
        <property type="entry name" value="PTHR30518"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02618">
        <property type="entry name" value="YceG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00247">
        <property type="entry name" value="TIGR00247"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="1 7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="5 7" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="27"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="7">
        <location>
            <position position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC91645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="351" mass="39300" checksum="015A1FFD9382407D" modified="2018-07-18" version="1">MRSNEHKFQIINLLQETRTIRVILKKLFSLFLLLALAAGAGFVYWATQPISGSAHEFTIKPGSSLRSSSQQIANAGVPIQPILFEVLARLNKQINSQDSTFKAGAFEAEAGITPLALLSKIVRGEFSQFSFALIEGWTFKQMRLAISQNPFLQHDTVEFSDAEILAKLNSEYDQPEGLFFPDTYLFPKGVSDMDVYKRAYSQLQQHLYTAWQQRDVAATPLKTPYEALILASIVEKETGMKSDRNMIAGVFVNRLRKGMLLQTDPTVIYGMGDQYQGKIRKRDLLQDTPYNTYTRTGLPPTPIALVGMESLMAALNPAHTDALYFVARGDGSSQFSSNLDDHNRAVNQFVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GV98</accession>
    <name>A0A2S9GV98_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3585</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000020">
        <property type="protein sequence ID" value="PRC91647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91647">
        <property type="protein sequence ID" value="PRC91647"/>
        <property type="gene ID" value="S2091_3585"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008551">
        <property type="entry name" value="TANGO2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17985">
        <property type="entry name" value="PTHR17985"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05742">
        <property type="entry name" value="TANGO2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="257" mass="28425" checksum="DD68D9818C317AF3" modified="2018-07-18" version="1">MCLIVFSWQVIGGYPLIAAANRDEYYSRETAPATWWADHPNIFAPRDLQAGGTWMGLTKLAGQDNSAGNKAGYKFAAITNVRDGSEVIQNAPSRGQLVSDYLIGADNVESYIQRISKHADHYNGFNLLVGEISETSQELCWFSNRNTSDARNGQLLTPGIYGLSNGTLDSPWPKVSKTKAELASLLCQHAPQEAFFEMLSNPIPAPDHRLPDTGVSLEMERLLSSTCIESENYGTRSSALLKICSNLEFQYLERVLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVA1</accession>
    <name>A0A2S9GVA1_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glycine dehydrogenase (decarboxylating)</fullName>
            <ecNumber evidence="7">1.4.4.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Glycine cleavage system P-protein</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Glycine decarboxylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Glycine dehydrogenase (aminomethyl-transferring)</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">gcvP</name>
        <name evidence="9" type="ORF">S2091_3587</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 7">The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>(R)-N(6)-lipoyl-L-lysyl-[glycine-cleavage complex H protein] + glycine + H(+) = (R)-N(6)-(S(8)-aminomethyldihydrolipoyl)-L-lysyl-[glycine-cleavage complex H protein] + CO2</text>
            <dbReference type="Rhea" id="RHEA:24304"/>
            <dbReference type="Rhea" id="RHEA-COMP:10494"/>
            <dbReference type="Rhea" id="RHEA-COMP:10495"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:83143"/>
            <dbReference type="EC" id="1.4.4.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 7 8">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="4 7">The glycine cleavage system is composed of four proteins: P, T, L and H.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the GcvP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.4.4.2" evidence="7"/>
    <dbReference type="EMBL" id="PUGF01000020">
        <property type="protein sequence ID" value="PRC91649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91649">
        <property type="protein sequence ID" value="PRC91649"/>
        <property type="gene ID" value="S2091_3587"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004375">
        <property type="term" value="F:glycine dehydrogenase (decarboxylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019464">
        <property type="term" value="P:glycine decarboxylation via glycine cleavage system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00613">
        <property type="entry name" value="GDC-P"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00711">
        <property type="entry name" value="GcvP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003437">
        <property type="entry name" value="GcvP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020581">
        <property type="entry name" value="GDC_P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11773">
        <property type="entry name" value="PTHR11773"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02347">
        <property type="entry name" value="GDC-P"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00461">
        <property type="entry name" value="gcvP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7 8" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="7 8">
        <location>
            <position position="709"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003788"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00033655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00711"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR603437-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC91649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="958" mass="104606" checksum="EB9DFD273825F88C" modified="2018-07-18" version="1">MVLQRAAQEHHEFNSEFISRHIGTSSTDIQFMLTTLGFATMDEFIRKVIPASILSEQALELGHANNEPEVLQLLREIAEQNQVLKSYIGMGYYNTHTPNVILRNLLENPAWYTAYTPYQPEISQGRLEALLNFQTMISDLTGMEIANASLLDEATAAAEAMTFCQRISKSKSSVFFVSEDCFPQTIAVIKTRAEPIGIQVVVGDHRTALKDLDFFGVLLQYPALSGEIYSYADTCKLAHDKQAMVVVAADLLALTLLTPPGEFGADVAIGTAQRFGVPLGFGGPHAAYFATKDTHKRQMPGRVVGVSIDSHGNPAYRLALQTREQHIRREKATSNVCTAQVLLANIASMFAVYHGPEGIKRIANRVHQLTATLVAGLKQLGYTVKNERYFDTIEVVTDTHTKVIHAVARGIEINLRQIDDARIGISIDETCTETDVQDIWAAFAASSQQVPDFKTVFAQTAECIPAELQRTSAYLTHPVFQRHRSETQMLRYLRMLSDKDLALDRTMIPLGSCTMKLNATAEMIPVTWPEFSNIHPFAPAEQTQGYARLITELEQMLVACTGYDAVSLQPNAGSQGEYAGLLAIRAYHHSRGDAHRNICLIPSSAHGTNPATAQMVGMQVVVVQCDEGGNVDVADLTAKAEQHAANLAALMITYPSTHGIFEAAIKEICAVIHTHGGQVYIDGANMNAMVGLCQPGKFGGDVSHLNLHKTFCIPHGGGGPGVGPIGVKSHLIPFLPGHHLLENQASPVCAAPWGSASILPISWTYIKLMGQEGLKQASQVAILNANYIAKRLSAHFPILYAGEGGIVAHECIVDLRPLKDETGVTVDDVAKRLMDFGFHAPTMSFPVPGTLMIEPTESEDRIELDRFCDAMIAIRAEIADVASGKISAEDSPLRHAPHTSMTLTAEWTHAYSREQAVFPIASLKNGSKYWPPVGRVDNVYGDRNVICSCPPLSDYETN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVD4</accession>
    <name>A0A2S9GVD4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">MCP-signal associated domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3612</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000020">
        <property type="protein sequence ID" value="PRC91674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91674">
        <property type="protein sequence ID" value="PRC91674"/>
        <property type="gene ID" value="S2091_3612"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025991">
        <property type="entry name" value="Chemoreceptor_zinc-bind_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13682">
        <property type="entry name" value="CZB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CZB" evidence="1">
        <location>
            <begin position="26"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="117" mass="12923" checksum="7CD2B4BB48B0F839" modified="2018-07-18" version="1">MDLRTAYESDKELKDQFIMAIEANAQVDATVIMKSDRCALGVWLHGEAERKFKFLSSYKPCMEAHEAFHAQAAKVARQINLGEHTSARSMLADGTPYAKACSSLGSALIMLKKDAKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVE4</accession>
    <name>A0A2S9GVE4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3622</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000020">
        <property type="protein sequence ID" value="PRC91684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91684">
        <property type="protein sequence ID" value="PRC91684"/>
        <property type="gene ID" value="S2091_3622"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016768">
        <property type="entry name" value="UCP019883"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10993">
        <property type="entry name" value="DUF2818"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF019883">
        <property type="entry name" value="UCP019883"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="75"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="101" mass="11572" checksum="84544A8A9D2C94FE" modified="2018-07-18" version="1">MQLSVAVWIVIVLALFGANLPFLNQRLFAVIPLRNAGSKKSFWLRLLELLVCYFLLGGLAYLFEVSIGNVFPQGWEFFAISACLFIVFAFPGFVYQYLRRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVI2</accession>
    <name>A0A2S9GVI2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alkylhydroperoxidase AhpD family core domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3490</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000019">
        <property type="protein sequence ID" value="PRC91735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91735">
        <property type="protein sequence ID" value="PRC91735"/>
        <property type="gene ID" value="S2091_3490"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051920">
        <property type="term" value="F:peroxiredoxin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029032">
        <property type="entry name" value="AhpD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004675">
        <property type="entry name" value="AhpD_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003779">
        <property type="entry name" value="CMD-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02627">
        <property type="entry name" value="CMD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69118">
        <property type="entry name" value="SSF69118"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00778">
        <property type="entry name" value="ahpD_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CMD" evidence="1">
        <location>
            <begin position="33"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="117" mass="12586" checksum="0BCC62B1755D4CB1" modified="2018-07-18" version="1">MVALWQAETKLGENIMHSMDNLEKLKTLGELSPKTTNAFWAFDRLALADGAIPKKYKELMAIAVALTTQCVYCIEVHRKAALEAGASPTELAEVIHVAAALRAGAAITHGTHLLSSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVL8</accession>
    <name>A0A2S9GVL8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="9">FtsX-like permease family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_3524</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000019">
        <property type="protein sequence ID" value="PRC91769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91769">
        <property type="protein sequence ID" value="PRC91769"/>
        <property type="gene ID" value="S2091_3524"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="252"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="306"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="348"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="429"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="672"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="720"/>
            <end position="745"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="773"/>
            <end position="793"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="8">
        <location>
            <begin position="288"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="8">
        <location>
            <begin position="705"/>
            <end position="798"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC91769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="807" mass="87686" checksum="E4C10B211B63B149" modified="2018-07-18" version="1">MTTFWRKAIADFWQERTRTALVVIAIALGVTGFTAVLSSYAILTRELNDDYLATNPASATLYTDKVDDTLLSTILENPQVGTAEPRRVVTGKIKSGPAEWRNLVLFVINDFNNLRVSTVQHEQGAWPPATGEILIERDAFQVAKTKIGEHVTIKMTSGQEHTLLVSGGVHDVGQAQARMDNLVYGYITLATLAELGEQPYLDQLKIVVANDGFNQAHIREVAAGIEKIIIKNGHSVLKIDVPVPGEHPHTQIMGMLLLVMAGFGVLVLLLSGVLVVNLLMALMAAQIRQIGVMKAIGGSRWQIAQIYFSQALFLGLASLLIAVPAGLWGGRELCRFLGVFLNFDINSFAVPLWIFLLIAAIGVVTPLLAAAHPILKACSVSVRTALSDVGVVHNQYRSSWFDQLLAHLSGERPTLLFALRNVFRRRTRLILTLITLSVAGVFFMAALNVRASMIDTLDHLFATRQFDLTVNFVGMAPDDAVTRAVSNTAGITRAETWINADAIFSAKGESDNATEQETHTSDENKFTVIALPEQTAMFKPNIIEGRNLLPGETDAIVVNHVLADKIPAIKVGAIIKLKIGSEKNGYQQNQWHVVGIAREPFSSAAGYIPKAYYAATKPNMSNSVNLVLTRTDEGAINAVKADLERNLEQQGIHARSNYTKGEGRSVIDEHIVMIYVFLIIMAGIVGGVGGLGLMTTMSLNVLERRREMGVLRTIGATPRTVWLIVASEGALIGLMSSVLAIAAAWPISKGIGDMLVGLMLRSVLDFRFDPSGIWIWLAVSVVLAVAASFMPAWQASRSSARDALACE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVQ2</accession>
    <name>A0A2S9GVQ2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative Ser protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3533</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000019">
        <property type="protein sequence ID" value="PRC91778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91778">
        <property type="protein sequence ID" value="PRC91778"/>
        <property type="gene ID" value="S2091_3533"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013153">
        <property type="entry name" value="Prk_AAA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010650">
        <property type="entry name" value="PrkA_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016230">
        <property type="entry name" value="Ser_kinase_PrkA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08298">
        <property type="entry name" value="AAA_PrkA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06798">
        <property type="entry name" value="PrkA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000549">
        <property type="entry name" value="Ser_prot_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00763">
        <property type="entry name" value="AAA_PrkA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AAA_PrkA" evidence="1">
        <location>
            <begin position="19"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="640" mass="73723" checksum="81BD84B279CDBE0B" modified="2018-07-18" version="1">MKIFDNYAARYERTREEEYSLQEYLELCKRDRLAFASAAERLLAAIGEPELVDTRHDPRRSRIFANKIIKIYPAFREFYGMEEVVEQVVSYFRHAAQGLEERKQILYLLGPVGGGKSSIAEKLKALMEKIPFYAIKGSPINESPLGLFNEEEDGVILEEDFGIPRRYLRTIPSPWAVKRLHEFNGDINQFRVVKRYPSVLKQVAISKTEPGDENNQDISSLVGKVDIRKLEDYAQDDPDAYSYSGGLCLANQGLMEFVEMFKAPIKVLHPLLTATQEGNYKGTEGFGAIPFEGVILAHSNESEWKAFKNNRNNEAFLDRIYIVKVPYCLRVSDEIKIYEKLVRSSSLTQAPCAPGTLKMMAQFSVLSRLKEPENSSIFSKMLVYDGENLKDTDPKAKSKQEYSDYAGVDEGMNGLSTRFAFKIISKVFNFDTTEVAANPVHLLYVLEQQIEREQFAPEVEQKYFSYVKEYLAQRYIEFIGKEIQTAYLESYSEYGQNIFDRYVSFADFWIQDQEFRDPDTGESFDREALNNDLEKIEKPAGISNPKDFRNEIVNFVLRARAQNAGKNPTWNSYEKLRTVIEKKMFSNTEELLPVISFNAKASVDDANKHQEFVERMVAKGYTAKQVRLLCEWYLRVRKTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVT0</accession>
    <name>A0A2S9GVT0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phytanoyl-CoA dioxygenase (PhyH)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3521</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000019">
        <property type="protein sequence ID" value="PRC91766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91766">
        <property type="protein sequence ID" value="PRC91766"/>
        <property type="gene ID" value="S2091_3521"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008775">
        <property type="entry name" value="Phytyl_CoA_dOase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05721">
        <property type="entry name" value="PhyH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="275" mass="31497" checksum="D5AEC28CC54FDB8D" modified="2018-07-18" version="1">MQNQPYEFIVQPEIIESFQRDGAVCIRRLFTPDEVALLESGIEENLRAPSTRSKIASKADDPGRFFEDFSNWQEIDAYQRFIVHSRVGSVAAQLMQSDTARLYHDHLLVKEPNTRQKTPWHQDQPYYNIEGRQNCSMWMPVDPVTREATLEFVGGSHLGPWLMPRTFLDNQAKWFPEGSLTALPDIDADRSAWNILGWALEPCDAVFFHMLTLHGANGVGSARRRRVFSVRFLGDDVRHAPRQWKTSPEFPGLAEALPAGAAMQHPLFPLLWPRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVX0</accession>
    <name>A0A2S9GVX0_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transketolase</fullName>
            <ecNumber evidence="4">2.2.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">S2091_3561</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the transketolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.2.1.1" evidence="4"/>
    <dbReference type="EMBL" id="PUGF01000019">
        <property type="protein sequence ID" value="PRC91806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91806">
        <property type="protein sequence ID" value="PRC91806"/>
        <property type="gene ID" value="S2091_3561"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004802">
        <property type="term" value="F:transketolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd02012">
        <property type="entry name" value="TPP_TK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005475">
        <property type="entry name" value="Transketolase-like_Pyr-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005478">
        <property type="entry name" value="Transketolase_bac-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033248">
        <property type="entry name" value="Transketolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033247">
        <property type="entry name" value="Transketolase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005474">
        <property type="entry name" value="Transketolase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43522">
        <property type="entry name" value="PTHR43522"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02779">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02780">
        <property type="entry name" value="Transketolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00456">
        <property type="entry name" value="Transketolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00861">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="SSF52922"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00232">
        <property type="entry name" value="tktlase_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00801">
        <property type="entry name" value="TRANSKETOLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0786">Thiamine pyrophosphate</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TRANSKETOLASE_1" evidence="9">
        <location>
            <begin position="16"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007131"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS00801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC91806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="665" mass="71347" checksum="A09AD317B95B3D83" modified="2018-07-18" version="1">MLPPLSVTTKMANAIRALAMDAVQQANSGHPGMPMGMAEIAVALWSQHYSHNPANPHWINRDRFVISNGHGSMLHYALLHLTGYDLPMSELKNFRQLHSKTPGHPEVHITPGIETTTGPLGQGISNAVGMALSEKLLAAEFNQAGMPVVDHYTYVLLGDGCLMEGISHEVCSLAGTLGLNKLIALYDDNGISIDGHVEGWFADDTPKRFEAYGWNVIPAVNGHDAAAVAAAITAAKASDKPTMICCKTIIGQGSPNMAGTHNVHGAALGDKEIAAVRVAIDWPYAPFEIPADVYSAWDAKTAGAKREQDWNTLFAGYSAAHPQQAAELVRRMNGELPGNFNAVADAYIKQCTEKQETIATRKASQNAIQALAPAMPEFLGGSADLTGSNLTNWKECVAVRHNQAGNHINYGVREFGMSAIMNGIALHGGYLPFGATFLTFSDYSRNAIRMAALMQIRTLFVFTHDSIGLGEDGPTHQSVEHVSSLRLIPNLDNWRPCDTVESAVAWKQAVARKNGPSTLIFSRQNLPFQARTDEQIANIARGAYVLQDPANAQVILIATGSEIELAVKSAAELATKGIVARVVSMPSTDVFDRQDAAYKASVLPKGLPRVAIEAGVTDFWYKYVGLEGAVVGIDTFGESAPAGVLFKHFGFTVENVVAKVNSVLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVY9</accession>
    <name>A0A2S9GVY9_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Peptidyl-prolyl cis-trans isomerase</fullName>
            <shortName evidence="2">PPIase</shortName>
            <ecNumber evidence="2">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_3445</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the cyclophilin-type PPIase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="2"/>
    <dbReference type="EMBL" id="PUGF01000018">
        <property type="protein sequence ID" value="PRC91889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91889">
        <property type="protein sequence ID" value="PRC91889"/>
        <property type="gene ID" value="S2091_3445"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000413">
        <property type="term" value="P:protein peptidyl-prolyl isomerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020892">
        <property type="entry name" value="Cyclophilin-type_PPIase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044665">
        <property type="entry name" value="E_coli_cyclophilin_A-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43246">
        <property type="entry name" value="PTHR43246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="SSF50891"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00170">
        <property type="entry name" value="CSA_PPIASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0697">Rotamase</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015373276" description="Peptidyl-prolyl cis-trans isomerase" evidence="2">
        <location>
            <begin position="27"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="4">
        <location>
            <begin position="40"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="232"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU363019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC91889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="263" mass="28410" checksum="1F9A3DCC4AE3D279" modified="2018-07-18" version="1">MQLRSYLRLPVVTLLSGLLLSTACLAAEPASSAPQVELKTNVGTIVLELYPDAAPKTVKNFLQYVKSGFYTGTIFHRVIDNFMIQGGGMGKDLKEKKMNAPIPLEAQMAIDHGLKNDIGTIAMAREEKPNTATSEFFINVANNDFLNPMTLPDGDPVQFTRHGKLQTLPRAQALLISAGYAPFGRVIQGMDVVNQIKVVQTDAVGENQNLPRKPIIVLSAKILKTHIKPKSIEEQTASSAVPAVTTPVPATEPATPQTAPQTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GW24</accession>
    <name>A0A2S9GW24_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ABC-2 family transporter protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3454</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000018">
        <property type="protein sequence ID" value="PRC91898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91898">
        <property type="protein sequence ID" value="PRC91898"/>
        <property type="gene ID" value="S2091_3454"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="182"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="225"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="264"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="298"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="356"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="384" mass="42412" checksum="F95A5CDCFBF069AC" modified="2018-07-18" version="1">MRLYWSSLSALLADKGALLLLVGAVVLYSFFYPLPYQNQVLQQVPVMIVDLDQTSLSRQIVRFAKTSSKLDVQEVVMDEGVAQQAMWQGDIQGYLILPKGMRESAVRGKKIVLPILGDGAYFLLNKTVLAGFAESVGTLSAGIEMKKLQAAGQHKLQADVSRNPVTLTMQALYNPTEGYGGYIVPAVAVVILQQTFLIGLMLFIGLLAERGSVLNQLGVTKISDVVSVLCAFATPVFLQGLYWFGWVFWWNDYPRLGTTEASSVSAVLLLLLVFSLTLAPLGLLLGMWFSNRERAMQVMLFTSIPMVFLAGFAWPAEALPEFLHWFRLLLPTTPGVQGFLKVNQFGASLTDIWPEFLHLGIMACVGWSAVLFAAWRSLRLSPQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GW45</accession>
    <name>A0A2S9GW45_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Dual-specificity RNA methyltransferase RlmN</fullName>
            <ecNumber evidence="13">2.1.1.192</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">23S rRNA (adenine(2503)-C(2))-methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">23S rRNA m2A2503 methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Ribosomal RNA large subunit methyltransferase N</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">tRNA (adenine(37)-C(2))-methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">tRNA m2A37 methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">rlmN</name>
        <name evidence="15" type="ORF">S2091_3474</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>adenosine(2503) in 23S rRNA + 2 reduced [2Fe-2S]-[ferredoxin] + 2 S-adenosyl-L-methionine = 2-methyladenosine(2503) in 23S rRNA + 5'-deoxyadenosine + L-methionine + 2 oxidized [2Fe-2S]-[ferredoxin] + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42916"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="Rhea" id="RHEA-COMP:10152"/>
            <dbReference type="Rhea" id="RHEA-COMP:10282"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74497"/>
            <dbReference type="EC" id="2.1.1.192"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>adenosine(37) in tRNA + 2 reduced [2Fe-2S]-[ferredoxin] + 2 S-adenosyl-L-methionine = 2-methyladenosine(37) in tRNA + 5'-deoxyadenosine + L-methionine + 2 oxidized [2Fe-2S]-[ferredoxin] + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:43332"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="Rhea" id="RHEA-COMP:10162"/>
            <dbReference type="Rhea" id="RHEA-COMP:10485"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74497"/>
            <dbReference type="EC" id="2.1.1.192"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="13">Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 13">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="13">Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the radical SAM superfamily. RlmN family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.192" evidence="13"/>
    <dbReference type="EMBL" id="PUGF01000018">
        <property type="protein sequence ID" value="PRC91918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91918">
        <property type="protein sequence ID" value="PRC91918"/>
        <property type="gene ID" value="S2091_3474"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070040">
        <property type="term" value="F:rRNA (adenine-C2-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002935">
        <property type="term" value="F:tRNA (adenine-C2-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070475">
        <property type="term" value="P:rRNA base methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01849">
        <property type="entry name" value="RNA_methyltr_RlmN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040072">
        <property type="entry name" value="Methyltransferase_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027492">
        <property type="entry name" value="RNA_MTrfase_RlmN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004383">
        <property type="entry name" value="rRNA_lsu_MTrfase_RlmN/Cfr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30544">
        <property type="entry name" value="PTHR30544"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006004">
        <property type="entry name" value="CHP00048"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00275">
        <property type="entry name" value="adenosine_C2_methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00048">
        <property type="entry name" value="rRNA_mod_RlmN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 13" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="4 13" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="12 13" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="10 13" id="KW-0408">Iron</keyword>
    <keyword evidence="11 13" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="9 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 13 15" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 13" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="8 13" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="7 13 15" id="KW-0808">Transferase</keyword>
    <keyword evidence="13" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Radical SAM core" evidence="14">
        <location>
            <begin position="99"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="13">
        <location>
            <begin position="172"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="13">
        <location>
            <begin position="226"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="13">
        <location>
            <position position="93"/>
        </location>
    </feature>
    <feature type="active site" description="S-methylcysteine intermediate" evidence="13">
        <location>
            <position position="346"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="113"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="117"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="120"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="204"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="303"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="PRC91918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="384" mass="42618" checksum="02C5D0F09BB16BAE" modified="2018-07-18" version="1">MTAITNLLDLDPAQLIAYCGELGEKPFRAKQLQRWIHQFGVSDFEAMTDLAKSLRDKLAGRACVSSPAVISDHTSTDGTRKWLLDVGQGNAIETVFIPEENRGTLCISTQAGCAVNCRFCSTGKQGFNRNLTVAEIIGQLWMAEFELRKTKGMIAGQKGERQITNVVMMGMGEPLLNFEPTVTALKLMLDDNAYGLSRRRVTLSTSGVVPMIDKLSQECPVALAVSLHASNDVLRDGLIPLNKKHPLSELMAACKRYLEFAPRDFVTFEYCMLEGVNDGDHHARELLELVRDVPCKFNLIPFNPFPESGLKRSNNLRIKAFAQILSDGGLVTTIRKTRGDDIDAACGQLAGEVQDRTRVQERMQKQAEYQKKFGSNFGRIVEIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GW88</accession>
    <name>A0A2S9GW88_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases large terminal subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_3331</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000017">
        <property type="protein sequence ID" value="PRC91989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91989">
        <property type="protein sequence ID" value="PRC91989"/>
        <property type="gene ID" value="S2091_3331"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.102.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017941">
        <property type="entry name" value="Rieske_2Fe-2S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036922">
        <property type="entry name" value="Rieske_2Fe-2S_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015879">
        <property type="entry name" value="Ring_hydroxy_dOase_asu_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001663">
        <property type="entry name" value="Rng_hydr_dOase-A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43756">
        <property type="entry name" value="PTHR43756"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00355">
        <property type="entry name" value="Rieske"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00848">
        <property type="entry name" value="Ring_hydroxyl_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00090">
        <property type="entry name" value="RNGDIOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50022">
        <property type="entry name" value="SSF50022"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51296">
        <property type="entry name" value="RIESKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="7" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rieske" evidence="6">
        <location>
            <begin position="44"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC91989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="414" mass="47282" checksum="EE0C1CFD491E3DF1" modified="2018-07-18" version="1">MSTPASPLRTLLDRRKSGYSLEAPFYTDPAIFEQDIKHIFGQHWIYVGPEVMVPEEGDFVTIEIGRTSVLIVRSDDMQVNAFHNVCRHRGSRLCTEHKGSVGNLVCPYHQWTYNLEGTLLFAEHMGESFNRSGHNLKPVHVRNIAGLIFICLAENPPKDIEDLAAAMTPYIAPHRISDCKIATQIDIIEDCNWKLTMENNRECYHCRGNHPELTISLYEYGFGYAPTPENCEGIDQYNQILEQRHQQWEAMGLPCRELDHLDDCITGFRTQRLPLDRAGQSQTMNAKVASSKLLADFQQADLGALSFWTQPNSWHHFMSDHIVTFTVLPISAEKTMVRTTWLVHKDAVEGRDYNLKDLTAVWVATNAQDRALVERSQQGIRSDAYEPGPYSPFTEMLVEKFCNWYTNRLSALAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWM1</accession>
    <name>A0A2S9GWM1_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RelA_SpoT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_3262</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000016">
        <property type="protein sequence ID" value="PRC92127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92127">
        <property type="protein sequence ID" value="PRC92127"/>
        <property type="gene ID" value="S2091_3262"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015969">
        <property type="term" value="P:guanosine tetraphosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05399">
        <property type="entry name" value="NT_Rel-Spo_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007685">
        <property type="entry name" value="RelA_SpoT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04607">
        <property type="entry name" value="RelA_SpoT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00954">
        <property type="entry name" value="RelA_SpoT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RelA_SpoT" evidence="4">
        <location>
            <begin position="67"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="234"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC92127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="420" mass="48241" checksum="514BBF75A2958F4A" modified="2018-07-18" version="1">MNSKITLGDFLLRNNILREEWLESKLNWDTLLNIGMHHETQISTLEDHAKILANAIQKFALVHSVKWRVKNTEHLLVKIIRKCAKNEPKYSAISVANYAEIVMDLIGIRVIHLFKSDFFNVDQSIRNHFSLSETAITYYREGDDKNYLENFKTPNFELKIHPVGYRSIHYVIKETVLKKLFFAEIQVRTIFEEGWSEIDHKIRYPNHTDNKYLQYFLAMFNRMAGSADEMGEFVKGLEAEFTRQKQEIDEASKAQNSTLEKVERMVEELQKHKEKNAKSNKQVENLQAEIKKLRGEQNLSIAISNNFYTGQISEVGKSIRTGINFDHGLHNAHNISKPLFEIAGRSESVITASRLISTGLPATVSTTTNKINFPWESTPLTTANPFVRTSGLLNPVITTATDLEHITNLTNSDKFGKKPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWM7</accession>
    <name>A0A2S9GWM7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3236</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000016">
        <property type="protein sequence ID" value="PRC92101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92101">
        <property type="protein sequence ID" value="PRC92101"/>
        <property type="gene ID" value="S2091_3236"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="427" mass="47173" checksum="89591EDD987CF2C2" modified="2018-07-18" version="1">MYTLKRPADVAKALDIGTLKDMWNAAIAYQNQGVYDTDAMYSIYQAMNPKLTIQDIGNVFSGVYADTYWNTTFLDASLLAKSLVQAIGLDRSLATTYANNAIAQWRGILSRKNISDTGSIPVVGNYTASLDIVCNQNTPIDPMALISNWNNEYWQQPSVGKNFIYSRCQNIAFNGAITKPQVQMFYSSGGFNQPPSSWIQCFTVKDNNPIGTVITQDGKTSPLNWGDRGCSEAFYFNPTSQDHVCVISATVSEFFASNNPKQIPPGNWNSATWITHNGAAAWHNVDPQRSVEDTLAFHNQDGTNENFTFYAQCRKVPVGSKITLRSEDPNAKFTTGTVNIDNPSQLVQLQVNLPAYHKGQLKVKLEGPDGRCLPVTAAVEVKMAWRLSHSHDYYADAVATFGNTNQHNANREIQLDMGTFTILGSGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWT7</accession>
    <name>A0A2S9GWT7_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Succinate dehydrogenase cytochrome b556 subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">S2091_3098</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
        <text evidence="9">The heme is bound between the two transmembrane subunits.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92182">
        <property type="protein sequence ID" value="PRC92182"/>
        <property type="gene ID" value="S2091_3098"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045281">
        <property type="term" value="C:succinate dehydrogenase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000104">
        <property type="term" value="F:succinate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1300.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034804">
        <property type="entry name" value="SQR/QFR_C/D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014314">
        <property type="entry name" value="Succ_DH_cytb556"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000701">
        <property type="entry name" value="SuccDH_FuR_B_TM-su"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01127">
        <property type="entry name" value="Sdh_cyt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000178">
        <property type="entry name" value="SDH_cyt_b560"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81343">
        <property type="entry name" value="SSF81343"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02970">
        <property type="entry name" value="succ_dehyd_cytB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 9" id="KW-0349">Heme</keyword>
    <keyword evidence="6 9" id="KW-0408">Iron</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="30"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="70"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="110"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="9">
        <location>
            <position position="86"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <note>ligand shared with second transmembrane subunit</note>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00020076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00025912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000178-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC92182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="133" mass="14933" checksum="DE691DF772C5D500" modified="2018-07-18" version="1">MPEAHRPQFRNIHVTQLAKYRLPLAGIVSILHRISGVLMFLLLPFILYLLDNSLTSEDTFAYLKGYIQFPLVKLIILVLSWAYLHHFCAGVRHVAMDMHVGLDKDTARKSAAGIFMVSIPLAALVALKLFGAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWW5</accession>
    <name>A0A2S9GWW5_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">50S ribosomal protein L32</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpmF</name>
        <name evidence="7" type="ORF">S2091_3126</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the bacterial ribosomal protein bL32 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92210">
        <property type="protein sequence ID" value="PRC92210"/>
        <property type="gene ID" value="S2091_3126"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00340">
        <property type="entry name" value="Ribosomal_L32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002677">
        <property type="entry name" value="Ribosomal_L32p"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044957">
        <property type="entry name" value="Ribosomal_L32p_bact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011332">
        <property type="entry name" value="Ribosomal_zn-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35534">
        <property type="entry name" value="PTHR35534"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01783">
        <property type="entry name" value="Ribosomal_L32p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57829">
        <property type="entry name" value="SSF57829"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01031">
        <property type="entry name" value="rpmF_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC92210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="60" mass="6925" checksum="EB1573EE7716E601" modified="2018-07-18" version="1">MAVQQNKKTPSKRGMHRSHDFLVAPQLSIEPTTGETHMRHHISPNGFYRGRKVLKTKNDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWY7</accession>
    <name>A0A2S9GWY7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_3146</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in DNA recombination.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RmuC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92230">
        <property type="protein sequence ID" value="PRC92230"/>
        <property type="gene ID" value="S2091_3146"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003798">
        <property type="entry name" value="DNA_recombination_RmuC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30563">
        <property type="entry name" value="PTHR30563"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02646">
        <property type="entry name" value="RmuC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="69"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC92230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="456" mass="51032" checksum="09C5B40C8631357F" modified="2018-07-18" version="1">MEASVFLIVGLGLGALFAWIVVNLKTRNQVAEMRQQGETEIAILKERLAGQSAVVAQAQQRAIDTQVKHSEQQQQLAGQQARIAELTTRLEAERLQTSEKLALLEAARSEFGQQFQLLANQILEEKSQKFTEQNKINLGGILLPLQEKINQFQTQVADTYDKDSKERLTLKNEIERLATLNGKISEDAINLTQALKGNNKTQGIWGEMVLETVLESSGLRRGEEYQVQNSFERDEGGLHRPDVIIHLPEGRHMIVDAKMSLVAYERYVSAANDDERAESLKLHLVSVRAHIKGLSEKNYQTLTGLKAPDFVMLFIAVEPAFMLAFSHDQSLFNDALAKNVLLVSPSTLLANLRTIAYIWRQEQQNRNAQEIAQQCAKLYDKFVGFVEDLEDIGKKLGQTQKSFDDAKSKLSSGRGNLIRQAEQVKKLGVKPTKNLPVQLLDEGDVDDDNEAVAQIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GX40</accession>
    <name>A0A2S9GX40_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Polysaccharide deacetylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2927</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92268">
        <property type="protein sequence ID" value="PRC92268"/>
        <property type="gene ID" value="S2091_2927"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002509">
        <property type="entry name" value="NODB_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01522">
        <property type="entry name" value="Polysacc_deac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="SSF88713"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51677">
        <property type="entry name" value="NODB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NodB homology" evidence="1">
        <location>
            <begin position="2"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="311" mass="34580" checksum="FCA98484DE02A7A2" modified="2018-07-18" version="1">MPTITLKIDVDTYRGSREGTPNLVRLLSQHKANATFLFSLGPDHTGWALRRAFKPGFFQKVSRTSVLEHYGLKTLMYGVLLPAPDIGLTCAAQLRAVAEAGFECGIHTWDHVLWQDNVRQRDAAWTKKQMQQSVDRFTSIFGVAPKTHGAAGWQMNPHAFAELDNLGMAYSSDGRAQLHEDGSLVEPHIGPYRLSIADKTLNCIQMPTTLPTLDELLGRTIDGKVIELHNIAEHILKLTKQPRDHVFTLHAELEGQKLAPIFEKLLIGWQAQGYQCSSMAEYASTIAPAQLPSRPLHWAELPGRSGELIMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GX51</accession>
    <name>A0A2S9GX51_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cytochrome c peroxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_2956</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92297">
        <property type="protein sequence ID" value="PRC92297"/>
        <property type="gene ID" value="S2091_2956"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004852">
        <property type="entry name" value="Di-haem_cyt_c_peroxidsae"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03150">
        <property type="entry name" value="CCP_MauG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0349">Heme</keyword>
    <keyword evidence="3 4" id="KW-0408">Iron</keyword>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015606160" evidence="5">
        <location>
            <begin position="23"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="6">
        <location>
            <begin position="70"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="6">
        <location>
            <begin position="254"/>
            <end position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC92297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="441" mass="48638" checksum="52112CBABBFFDFFF" modified="2018-07-18" version="1">MRNCFKSLFCLFLVMLLGACQKQSSPTAATQSAPSSVLPAPAYAQAPTAAYPKKNASWVRYPDQSVPLSPQAELGRKLFFDISLSASGQMSCATCHNPDHAYAPINDLAVQLGGPKLDRAGTRSVPSLRYISFTPLFTRHFYLPGPEGLEDEGPTGGFTHDGAIRTLHEQASIPLLSANEMANLDAASVAQKVQVAVYAKQFQQVYGEQVFSNVNKTLEQVGNALEAFQMEDASFHPYTSKFDAVVSGNATFTDAELRGYRVFKDPSKGNCAKCHIDTVGAGGSPAQFTDFEFEAIGVPRNPAIPANRSTSYFDMGICGPYRKDMSRETLFCGMFKTPTLRNVVTRKVFFHNGYFHDLDEVMHFYVERDRKPQKWYSKVHGKVQMFDDLPKQYQDNVDHVTAPFNRKKGAPAALNEAEIKDLIEFLTTLSDGYSAKPGAEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXQ6</accession>
    <name>A0A2S9GXQ6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alpha/beta hydrolase fold</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2877</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92502">
        <property type="protein sequence ID" value="PRC92502"/>
        <property type="gene ID" value="S2091_2877"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015640182" evidence="1">
        <location>
            <begin position="21"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="domain" description="Abhydrolase_3" evidence="2">
        <location>
            <begin position="156"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="326" mass="35932" checksum="7DD94F1B6EBEF968" modified="2018-07-18" version="1">MRILCLFLFAISTIFSSAHSFSDNADKFTQLQTQEPIHEPVQIQLWPDAVPDARPSTESETREIEKTKLVAGKQWSYISHVARPTMTIYSPKGANANAAVLVFPGGGYNVLAIDLEGTEVCDWLTGIGVTCIVLKYRVPHSGTQWNEKCQCQATPKIPAALEDAQRAVSLIRFHAAEWNIDPHKIGVLGFSAGGHLVAAVSTHFSKRTYHAIDSADQQSSRPDFAVALYPGHLSWIKNSLVLNPEIASYITAQTPTTFLLQNEDDHVDSVMDSLSYYVALRKAGVPVELHSYAEGGHAFGLRRTEFPATAWPTLVETWLTTIGVKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXS4</accession>
    <name>A0A2S9GXS4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Tautomerase enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2888</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92513">
        <property type="protein sequence ID" value="PRC92513"/>
        <property type="gene ID" value="S2091_2888"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006725">
        <property type="term" value="P:cellular aromatic compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.429.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004370">
        <property type="entry name" value="4-oxalocrotonate_tautomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014347">
        <property type="entry name" value="Tautomerase/MIF_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01361">
        <property type="entry name" value="Tautomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55331">
        <property type="entry name" value="SSF55331"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tautomerase" evidence="1">
        <location>
            <begin position="9"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="145" mass="16460" checksum="AE9C58E22DC67F7D" modified="2018-07-18" version="1">MPGIMLKISGRETHDQTVSFADELTSLACSVLNKEASQTMVIIQFVPHEQWFIGRRSLAELGKNSFRLEVTITDETNTKSQKAQFHRDAFELLSRMLGNVHPHSNVHIIDCRATAYGYGGITQEYRYQRAIYAEVKAVAERKVQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXT3</accession>
    <name>A0A2S9GXT3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Helix-hairpin-helix motif</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2592</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92537">
        <property type="protein sequence ID" value="PRC92537"/>
        <property type="gene ID" value="S2091_2592"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015522768" evidence="2">
        <location>
            <begin position="22"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="89"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="108" mass="11183" checksum="B129D5F90B6E1F8D" modified="2018-07-18" version="1">MFKKFLFAVFALVISMSIAIAAVDVNKADQAGLDGIKGIGPSTSKAILAERSKGEFKDWADFEKRVKGIGGKKSIKLSKAGLVVNGQSKADAPAKNATAAGSNSAVKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXU0</accession>
    <name>A0A2S9GXU0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">2Fe-2S iron-sulfur cluster binding domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2851</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92476">
        <property type="protein sequence ID" value="PRC92476"/>
        <property type="gene ID" value="S2091_2851"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.440">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042204">
        <property type="entry name" value="2Fe-2S-bd_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="SSF54292"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="86" mass="9384" checksum="DDECE33C35EDC080" modified="2018-07-18" version="1">MPHDATITVDGRVILADTQMSVASAIALTDRLLTRRSVTGEARFAVCGMGVCQECRVTINGVPHRLACQTRCLPDMVILTGREEQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXX1</accession>
    <name>A0A2S9GXX1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2618</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92563">
        <property type="protein sequence ID" value="PRC92563"/>
        <property type="gene ID" value="S2091_2618"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="393" mass="43771" checksum="4E77F1450AAE3648" modified="2018-07-18" version="1">MTSQPRPYRSLYTYAWDVIDQGIATFVEDALSLGITDVSLATSYHAGKFIRPHAQRGPRVIFPEDGVVYFDPQLSHYGEIKPQAHSDPAMRRVLPDLLADARLRVHGWTVLLHNSRIGSAFPHYCTQNVFGDAYVYSLCPMQPAVFDYAVALSADLAGQHAVQSLILETPGWLPYAHGYHHEFAQIEMTPNLDQALGLCFCSACKLAAKKQEINVEDLQLRLQNYISNYFNSDVNGGSEQIQTTDDLLSYVKMRQNRVTELVSKIREVIPATTQLAVIPTVQRPTANCWTEGSDLAALASVADYLEIPFYEPSAKQVLADAWDSLQRIGADNKVRGILRPGHPDLKPASEITAALEGLQQLGIRDIGFYNYGLLPRHQLNKLMQCLTNLKALS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GY05</accession>
    <name>A0A2S9GY05_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2662</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92607">
        <property type="protein sequence ID" value="PRC92607"/>
        <property type="gene ID" value="S2091_2662"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032314">
        <property type="entry name" value="DUF4845"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16137">
        <property type="entry name" value="DUF4845"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="121" mass="12790" checksum="1DC13CE55C3B8008" modified="2018-07-18" version="1">MVGLSNLHKQRGLSLSGLILALILVAIAAVLGMQVVPAVVEFQSIKKAATDARDRGTSAPEIEAAYNKIAVAGYITSVSGKDLTIVKEDGVYQVSFAYEKKLPLFGPASLLLEFSGSTDKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GY81</accession>
    <name>A0A2S9GY81_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF4376 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2737</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92682">
        <property type="protein sequence ID" value="PRC92682"/>
        <property type="gene ID" value="S2091_2737"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025484">
        <property type="entry name" value="DUF4376"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14301">
        <property type="entry name" value="DUF4376"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4376" evidence="1">
        <location>
            <begin position="96"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14301"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="208" mass="22393" checksum="16D2825CBABCFA4D" modified="2018-07-18" version="1">MNSYGIYNATSGVINRIISTDQNNIALNVQAGESAIILLNDETDDKFYVSNGIITAYTSTELQLIATLPIGCIWSMPSRAVVDTAVMADIQARACAAINVKRDAVIAAFDQFTYNGVVYDGDVLAQANIQMTIDVITAGIPLPANFEWRASDNSMHPMAAADVISMNAARLVAQATLVFATYSTSWTLKAQINSATTRQQVEAITWSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYJ3</accession>
    <name>A0A2S9GYJ3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2456</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92726">
        <property type="protein sequence ID" value="PRC92726"/>
        <property type="gene ID" value="S2091_2456"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="151" mass="16821" checksum="05537CBDB306FC53" modified="2018-07-18" version="1">MISRKTFILLFLSTLLLQGCSPNSFFINLFSDGSKLELVSIDHDSDSSLTQDSVVTANLKYEIPHFESNKYFVIAQFSTTNSSSTTDGNFPANRYPIIVTPSGSIQINFPLMYVLNSPNIKRPLTMYFFLNEKVGQNSGHVVAMVGPIELK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYL1</accession>
    <name>A0A2S9GYL1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyltransferase family 9 (Heptosyltransferase)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2542</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92812">
        <property type="protein sequence ID" value="PRC92812"/>
        <property type="gene ID" value="S2091_2542"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002201">
        <property type="entry name" value="Glyco_trans_9"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01075">
        <property type="entry name" value="Glyco_transf_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="372" mass="43149" checksum="11B4AD5A3F0D9525" modified="2018-07-18" version="1">MTTQLVPAELLQKTDKILFVAHLALGDFTYMQNCFRAFSEAYPHIKMHLWVDELRRTPDATQWDHLKKYSLYDWVNSCPMFDKIYSETYSPTLFKKSIQEARTENYPIVVSFAVHHRHRYVNLARKLSPRGFIVGQKKRVRFFDIRKHLIYRKLNAHIPAYQITKQHQAGDLNIAHISSIYAGWFNQLFNLTTTEAQRFPFVDIPAKWHDYAQQQFSDWGFNNGAKVVFLNGFSKSLDRSWPLERVFELATEMKKHAAWSNTNFIINVVPERMAEAKLLYANCQLGQVHLFSAEQNFFQLPAILSLCNLIISVETAVMHLANAVHVPVIALMRQTSPEWTPINAEITTIVKVSHRKAWIDEITVDQVVAALP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYL2</accession>
    <name>A0A2S9GYL2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">O-antigen ligase like membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_2545</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92815">
        <property type="protein sequence ID" value="PRC92815"/>
        <property type="gene ID" value="S2091_2545"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007016">
        <property type="entry name" value="O-antigen_ligase-related"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04932">
        <property type="entry name" value="Wzy_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="2 3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="7"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="29"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="61"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="88"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="120"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="147"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="174"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="197"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="223"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="328"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="360"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="384"/>
            <end position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC92815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="417" mass="47335" checksum="EE258309284A0839" modified="2018-07-18" version="1">MTNKPSYLYWPTLLTVITFFTVSLLVSKLVYLCFHLLILISIITFLVQRDARANFWSICKTYWAINLAMFGTLCALLINQLSTGSFDIYLYDLPSRLALFVVIFWTLLQVPLQKLKLIKWSWIAGVVLCTIQLFCMGKDVTGRPTMLVWYIELVMLLGIFSALSIGWNEPKNKLTIGIQIIAGACGLYSAYISQTRGIWLAIPVFTLLMFATLIKNWCSKRNFLFFGAIILVIGVAFCTTDIASKRIEDAKQDISLYSKQENPDTSIGVRFQIWQGAWIIFKEHPIFGVGRAHYSDAMHGLEERKIITPTAATFFHCHNEILYNMMTLGIFGLAGILLIYLVPAYYFARELRHSDRQIRASAAMGLSLCFGFMIFGLVDVMFMYKATDVFYSFAAAIFLAHIVKRKAELSLKSGLES</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYL3</accession>
    <name>A0A2S9GYL3_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA polymerase III subunit alpha</fullName>
            <ecNumber evidence="2">2.7.7.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">S2091_2539</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="2"/>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92809">
        <property type="protein sequence ID" value="PRC92809"/>
        <property type="gene ID" value="S2091_2539"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1600">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011708">
        <property type="entry name" value="DNA_pol3_alpha_NTPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041931">
        <property type="entry name" value="DNA_pol3_alpha_thumb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040982">
        <property type="entry name" value="DNA_pol3_finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029460">
        <property type="entry name" value="DNAPol_HHH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004365">
        <property type="entry name" value="NA-bd_OB_tRNA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004013">
        <property type="entry name" value="PHP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003141">
        <property type="entry name" value="Pol/His_phosphatase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016195">
        <property type="entry name" value="Pol/histidinol_Pase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004805">
        <property type="entry name" value="PolC_alpha"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32294">
        <property type="entry name" value="PTHR32294"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07733">
        <property type="entry name" value="DNA_pol3_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17657">
        <property type="entry name" value="DNA_pol3_finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14579">
        <property type="entry name" value="HHH_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02811">
        <property type="entry name" value="PHP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01336">
        <property type="entry name" value="tRNA_anti-codon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00481">
        <property type="entry name" value="POLIIIAc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89550">
        <property type="entry name" value="SSF89550"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00594">
        <property type="entry name" value="polc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0235">DNA replication</keyword>
    <keyword evidence="8" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="5" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="POLIIIAc" evidence="10">
        <location>
            <begin position="7"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC92809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="1151" mass="127686" checksum="1AA5A9DF6815D07C" modified="2018-07-18" version="1">MTTPQFIHLRLHSEYSIVDGLVRIDDAIQAAVKDQQPALAITDLSNLFGMVKFYKDARGKGLKPIAGCDIWITNDGQRDKPSRLLLLVKNHTGYLQLCELLSQAWISNQHLGRAEIRAEWLAALPPGGLIVLSGAHFGDIGIALENGNLDAARRCAQHWASVFPDHFYIEIQRANQPNMAAQVRQSVALAAELGLPVAATHPVQFIDASEFTAHEARTCIAEGEILANGRRVRRFNEDQYFKTQAEMQELFADLPGALANSVEIAKRCNLVLELGKPKLPLFPTPEGVTLDEFLVSEAQTGLQQRMLLLYPDPVEREKQQEKYASRLKFETDTIIKMGFPGYFLIVAEFILWAKNNGVPVGPGRGSGAGSLVAYSLKITDLDPLAYNLLFERFLNPDRVSMPDFDIDFCQEGRDRVIQHVKDLYGKEAVSQIATFGTMAAKGAIRDVGRVLDFGYNFCDGISKLIPFRPGKQVTIAEAIKEEPQLAERQENEDDVRRLLDLAQQVEGITRNIGMHAGGVLIAPGKLTDFCPLYTQGGDAGVVSQYDKDDVEAVGLVKFDFLGLTTLTILDWAVRYIKMLDPALAGFNLETLPLNDKASYTLLSKAKTVAVFQLESRGMQGMLKDARPDRFEDIIALVALYRPGPMDLIPDFCKRKHGERFDYPDPRTEGILSETYGIMVYQEQVMQMAQVVGGYSLGGADLLRRAMGKKKAEEMAEHRQIFRNGAAKDGLTEQKADEIFDLMEKFAGYGFNKSHAAAYALLAYHTAYLKAHHPAAFMAANLSLAMDDTDKIKILVEDAIDVCGLTLLPPDVNYSDYRFTPVGHPAGPSKPATQIRYGLGAVKGSGQNAIENIVAARKDGPFVDLFDFTKRVDKRQVNRRTIESLIRAGAFDGFSVDRGVLLASVGLAIECAEQAEAARHQVSLFDDDAAMSGSPDYVKAAVWSEKRKLSEEKLALGFYLSGHLFSIYAPEVRKFIRTPLSKLETSRDNRLMAGIISAMRTQMTQRGKILIVTLDDSTGTQDVTIYSELYDEFKHFFKEDEFLAVSGRVSEDRFSGGLRVTAEKVLDIAQARIQFAQGLRIEINNTMDVKQLQSTLDPHLNAQGCPILVQYQGEKASVELRFSDDWRVNPDDELQQKLVGLLSPEKVAIVYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYL7</accession>
    <name>A0A2S9GYL7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyltransferase family 9 (Heptosyltransferase)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2544</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92814">
        <property type="protein sequence ID" value="PRC92814"/>
        <property type="gene ID" value="S2091_2544"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002201">
        <property type="entry name" value="Glyco_trans_9"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01075">
        <property type="entry name" value="Glyco_transf_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="370" mass="42354" checksum="F19A0346243BB46D" modified="2018-07-18" version="1">MHLIPSETLAKAKKILFIAHLAIGDFTYLQNFFKAFAEAHPQLKVDLWIDEVRCTSDSSQWGFLKNYSLYDWTENCSFFHKVYRRTYSPALLQESIHEAQQENYPLVVSLATLRPHKYAKLAREVGGPNALIIGMKGKARWFAPWDNSAYAKLDASFAPFVRPSSGHHITEVYADWFKQLCGLQVTTQQRFPFVSIPTQWTDYAKQQLQEWGVTEEATNTGQQVVFINSYAKTKKRCWPLASVAELIVSMRALPAWRDSVFIVNAVPQEIDNARTVLASYHLTDTHLFSAEQNFFQLPAILQRCDLIISVETAVMHLANAVHVPVIALMRQKNPEWVPLDSNNSTVITTRRRREWVNAIPVEEIIKAITQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYP3</accession>
    <name>A0A2S9GYP3_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ribosomal silencing factor RsfS</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rsfS</name>
        <name evidence="6" type="ORF">S2091_2550</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Interacts with ribosomal protein L14 (rplN).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the Iojap/RsfS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92820">
        <property type="protein sequence ID" value="PRC92820"/>
        <property type="gene ID" value="S2091_2550"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042256">
        <property type="term" value="P:mature ribosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090071">
        <property type="term" value="P:negative regulation of ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017148">
        <property type="term" value="P:negative regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01477">
        <property type="entry name" value="Iojap_RsfS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004394">
        <property type="entry name" value="Iojap/RsfS/C7orf30"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21043">
        <property type="entry name" value="PTHR21043"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00090">
        <property type="entry name" value="rsfS_iojap_ybeB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0678">Repressor</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0810">Translation regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="137"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="149"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC92820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="228" mass="24776" checksum="DD34D50201397B9D" modified="2018-07-18" version="1">MDIKKLQTLVVDALEDVKAQDIKVYDTTHLTSLFDRICIASGTSNRQTKSLASSVRDKVKENGGDIVGIEGEDVGEWVLVDLGDMVVHIMQPVIRGYYRLEELWGDKEIKMGAAKRISKRTAEVVEEDAEPVKRVRSNINQATQTTLDDETKKPARKPRAAAVATDETKPKRASRAKVADADAAAAPKKPRVKKAIGTTIKVAASKTAVASAKQAAVKRTTAKRKAAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYX7</accession>
    <name>A0A2S9GYX7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2334</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92917">
        <property type="protein sequence ID" value="PRC92917"/>
        <property type="gene ID" value="S2091_2334"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010559">
        <property type="entry name" value="Sig_transdc_His_kin_internal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06580">
        <property type="entry name" value="His_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="80"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="112"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="175"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="2">
        <location>
            <begin position="326"/>
            <end position="422"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="426" mass="47330" checksum="755F983DC142164F" modified="2018-07-18" version="1">MDQQSTSIISADNPLPSKILGKYGGWGARAQQYPIFSQTWFKYRAMSYLLPMFLLALLLTFVCILMPIEDVTFSFTLSMALVWGSVAVALLLGRWLAVLISKRDWPEKRIGMGIVAAVILGIVIAVTLNRIGNFYEKKYFAEHQQDLNLKRKTDVSVGIQIDTHNNLKKNPTLAILNYLLVILFFSWLGGGLDVVAYFRQRRAMKDALVEQRLTLYKKERNEAELRLSVLASQIEPHFLFNTLSGVRSAILSDPQMGVAIIDNLVEYLRATIPQLRNDGSCAQVKLGAQLQAIRAYLGVIKFRIPRLSFDVYCDPVLAEQFIPPLMLISLVENAVKHGIELKKGPVYISVLAQKIGLKGKERLVLTVSDNGLGFSGITSGTGIGLANIRERLKQLYDDHASLSLEENDGGGVCACITIPANTDLIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZ01</accession>
    <name>A0A2S9GZ01_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glutamine synthetase</fullName>
            <ecNumber evidence="4">6.3.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_2369</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>ATP + L-glutamate + NH4(+) = ADP + H(+) + L-glutamine + phosphate</text>
            <dbReference type="Rhea" id="RHEA:16169"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.1.2"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the glutamine synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.1.2" evidence="4"/>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92952">
        <property type="protein sequence ID" value="PRC92952"/>
        <property type="gene ID" value="S2091_2369"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004356">
        <property type="term" value="F:glutamate-ammonia ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006542">
        <property type="term" value="P:glutamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008147">
        <property type="entry name" value="Gln_synt_b-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036651">
        <property type="entry name" value="Gln_synt_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014746">
        <property type="entry name" value="Gln_synth/guanido_kin_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008146">
        <property type="entry name" value="Gln_synth_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027303">
        <property type="entry name" value="Gln_synth_gly_rich_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004809">
        <property type="entry name" value="Gln_synth_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027302">
        <property type="entry name" value="Gln_synth_N_conserv_site"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00120">
        <property type="entry name" value="Gln-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03951">
        <property type="entry name" value="Gln-synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01230">
        <property type="entry name" value="Gln-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54368">
        <property type="entry name" value="SSF54368"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55931">
        <property type="entry name" value="SSF55931"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00653">
        <property type="entry name" value="GlnA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00180">
        <property type="entry name" value="GLNA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00181">
        <property type="entry name" value="GLNA_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gln-synt_C" evidence="5">
        <location>
            <begin position="104"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-AMP-tyrosine" evidence="2">
        <location>
            <position position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR604809-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC92952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="471" mass="52263" checksum="00533AA3B499896E" modified="2018-07-18" version="1">MAMTVAEVLKMAKDNEVKFVDFRFTDTRGKEQHVTVPVSQFDIDKFESGHAFDGSSIAGWKGIESSDMLLMPDPNTANIDPFMEETTLFMQCDVIEPSDGKGYDRDPRSIAKRAEAYLKSTGLGDTAYFGPEPEFFIFDGVRWKIDMSGCFVKIDSGEASWSTDAKIEGGNTGHRPTVKGGYFPVPPVDSFQDMRSEMCLILESLGIPVEVHHHEVAGAGQNEIGTKFSTLVERADWTQNLKYVVWNVAHTYGKTATFMPKPIVGDNGSGMHVHQSVWKDGKNLFAGDGYAGLSEFALYYIGGIIKHARALNAITNPGTNSYKRLVPGYEAPVKLAYSARNRSASIRIPYVANPKGRRVEARFPDPLANPYLCFAALLMAGLDGVQNKIHPGEAASKDLYHLPPEEDALIPTVCESLEQALGYLDKDREFLTRGGVFSDTMIDAYIELKKKEVERLNMTTHPVEFDMYYSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZ34</accession>
    <name>A0A2S9GZ34_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ubiquinone biosynthesis O-methyltransferase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">2-polyprenyl-6-hydroxyphenol methylase</fullName>
            <ecNumber evidence="1">2.1.1.222</ecNumber>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">3-demethylubiquinone 3-O-methyltransferase</fullName>
            <ecNumber evidence="1">2.1.1.64</ecNumber>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">ubiG</name>
        <name evidence="2" type="ORF">S2091_2416</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 3-(all-trans-polyprenyl)benzene-1,2-diol + S-adenosyl-L-methionine = a 2-methoxy-6-(all-trans-polyprenyl)phenol + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:31411"/>
            <dbReference type="Rhea" id="RHEA-COMP:9550"/>
            <dbReference type="Rhea" id="RHEA-COMP:9551"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:62729"/>
            <dbReference type="ChEBI" id="CHEBI:62731"/>
            <dbReference type="EC" id="2.1.1.222"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 3-demethylubiquinol + S-adenosyl-L-methionine = a ubiquinol + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:44380"/>
            <dbReference type="Rhea" id="RHEA-COMP:9566"/>
            <dbReference type="Rhea" id="RHEA-COMP:10914"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17976"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:84422"/>
            <dbReference type="EC" id="2.1.1.64"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; ubiquinone biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. UbiG/COQ3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.222" evidence="1"/>
    <dbReference type="EC" id="2.1.1.64" evidence="1"/>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92999">
        <property type="protein sequence ID" value="PRC92999"/>
        <property type="gene ID" value="S2091_2416"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00232"/>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102208">
        <property type="term" value="F:2-polyprenyl-6-hydroxyphenol methylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008425">
        <property type="term" value="F:2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008689">
        <property type="term" value="F:3-demethylubiquinone-9 3-O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006744">
        <property type="term" value="P:ubiquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00472">
        <property type="entry name" value="UbiG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010233">
        <property type="entry name" value="UbiG_MeTrfase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01983">
        <property type="entry name" value="UbiG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="1 2" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0830">Ubiquinone</keyword>
    <keyword evidence="1" id="KW-0831">Ubiquinone biosynthesis</keyword>
    <feature type="binding site" evidence="1">
        <location>
            <position position="35"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="54"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="75"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="119"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="231" mass="25282" checksum="71A8F8C8B05C93B7" modified="2018-07-18" version="1">MNADPLEIQKFSDVAHHWWDTSSEFRPLHEINPLRLEWIHARASLNGKKVIDVGCGGGILAESMAKKGASVTGIDLSEKALNVADLHSLESGLTIRYKHIAAEQMAAQEAGAYDVVTCMEMLEHVPDPSSIIAACAQLVKPGGLVFFSTLNRNPKSYLYAVLGAEYLLKLLPKGTHDYAKFITPAELAQAIRQAGLELLSLRGMSYNPLSKIYSLNSDTSVNYLAACRRPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZ52</accession>
    <name>A0A2S9GZ52_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PEP-CTERM protein-sorting domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2395</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92978">
        <property type="protein sequence ID" value="PRC92978"/>
        <property type="gene ID" value="S2091_2395"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013424">
        <property type="entry name" value="PEP_exosort_dom"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02595">
        <property type="entry name" value="PEP_exosort"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015454814" evidence="1">
        <location>
            <begin position="34"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="260" mass="26762" checksum="66D6D72D755ADF8F" modified="2018-07-18" version="1">MTSNTHLNLKKTLQSTASTCLLPLLFVCAQAHAGLIGYQGQTAFNAAITGMSTNTTDFESITAGTMYAPNTGPAGSGFTLVLTGPDAPQYAPTVSNQFWTTSGVNYLGLNNPDSALEVGDSMTFNFSSPVSGFGLFVIGSSDVGPGDISLTSGATTVSNGAVADITDGNGDYAYYIGLATNDLSTFSSVTISDLNGLSDRLLPIDMDDVTLASNQSGQGGSGGPTVPEPSSLALFLTGAVLLSLAIYRQRRLKPSTTRLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZ92</accession>
    <name>A0A2S9GZ92_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2104</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93018">
        <property type="protein sequence ID" value="PRC93018"/>
        <property type="gene ID" value="S2091_2104"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="329" mass="37246" checksum="EACC624F557D844D" modified="2018-07-18" version="1">MSHPEIIIPFSLPPAEHAKDLVKMLASECGTDGLAMLLSRHQTLKRTHFDDFSPELPHETWLTKTQQHSNLQQQASTLGVELTAGHWFILNPVHLHIARNHLVLTDYRQLALSEPDSILLYQKAQALCEEVGLELVYGNATSWFLRANDWADFATSTPDAACGHNIEIWSAKGQKELAWRKLQNEIQMEWFIHPLQEQRERRAEKVVNGLWLWGGTALKNGFKAEQIKPASPAHSVENFILTPQLTVLDQLSAAALANDWGTWAAGMIELERSWFKPLYTALKDRKLKQLHLHLSNSNTLLSVQTSGNALRKFWCVPTLKNLIDTSRAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZL7</accession>
    <name>A0A2S9GZL7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">RibD C-terminal domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2260</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93174">
        <property type="protein sequence ID" value="PRC93174"/>
        <property type="gene ID" value="S2091_2260"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008703">
        <property type="term" value="F:5-amino-6-(5-phosphoribosylamino)uracil reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.430.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024072">
        <property type="entry name" value="DHFR-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002734">
        <property type="entry name" value="RibDG_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01872">
        <property type="entry name" value="RibD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53597">
        <property type="entry name" value="SSF53597"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RibD_C" evidence="1">
        <location>
            <begin position="2"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="176" mass="19705" checksum="287C2D858FC7367D" modified="2018-07-18" version="1">MRKLTANLFISLDGVVEAPSTFMRPDLYGDIPEEYIAEQDTVLMGRKIYEEWSQFWPDSKIEPFASFINKHPKIVVSSTLRNLEWRNSTLLDGDLEGAVRKLKAQPGKTIGVHGISLIQSLLLAGLVDELHLTLVPAIAGRGRRLLDHQGAAIQLDLQNSRSTPRGLECLVYAVRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZN5</accession>
    <name>A0A2S9GZN5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phytanoyl-CoA dioxygenase (PhyH)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1937</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93199">
        <property type="protein sequence ID" value="PRC93199"/>
        <property type="gene ID" value="S2091_1937"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008775">
        <property type="entry name" value="Phytyl_CoA_dOase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05721">
        <property type="entry name" value="PhyH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="250" mass="27440" checksum="AADD7169E74D5035" modified="2018-07-18" version="1">MLTPHQLANFQQNGFLVLPQLADSAYCAEVLAFAQKQLADAVQPLELEADTGYLGAPESKAHAGGETVRRLLQVTLRGSLISDWATGPSLSEPLKQLLGNEIRLSQVHHNCIMTKQPRFSSVTGWHRDSRYWQFQRAELISAWLALRNETVENGCLLVIPSSHRVQVEAEGLDTAQFLRADYPANQALLAQAVAVPLNVGDVLLFSSNLFHAAGHNQTELTKFSMVFTYRALDNPPLAGSRSASLPEIAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZR1</accession>
    <name>A0A2S9GZR1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1928</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93190">
        <property type="protein sequence ID" value="PRC93190"/>
        <property type="gene ID" value="S2091_1928"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="493" mass="52240" checksum="F1B9B4C1EDE48684" modified="2018-07-18" version="1">MKNMKMANESWLKLIAAGSLLRQLPILMLIVITSIINSNAYATTSSIYVTNGAVLTYTETARAIKNVGCSDIPTLIMYTYGSFSYSGAQITNPTAVATFEFTGCQNSNLIDIPATLNLSNGCTILVNPSQGGVPSASLSCPNVSIHPKYVIVGVTYAPPGPSSYVQYTQSNLFGTTISDSQTYSAQTSLTTTASAGSLPGWISGKLQVSAGSSATQTRTSSNATTLSFTNLSSYKVMGPPSPPVSINTPINHNYDVIWLWLNPVAMYSVATNYVQFNGFAYNEADLAGVDIYPVLVGQLNGSIPMDPSLVQELSRSWASVQTFPAGDGPGLTLADFANILASDPFTNSAYSVSPSATTSGDKRFTLTGSTSVNGGAPAQSFIYAPGTVTETYSNTYVNSTLASSGVTNQTAQTYGVDFTVTATTQYGIYSLDLKTSNTQTWTYQQSKSLTNTSTQIDLLSLGTPCASCAYTGPTVFEVYQDNIFGTFMFNPVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H046</accession>
    <name>A0A2S9H046_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">UPF0250 protein S2091_2061</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2061</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0250 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93323">
        <property type="protein sequence ID" value="PRC93323"/>
        <property type="gene ID" value="S2091_2061"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00659">
        <property type="entry name" value="UPF0250"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007454">
        <property type="entry name" value="UPF0250"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027471">
        <property type="entry name" value="YbeD-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38036">
        <property type="entry name" value="PTHR38036"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04359">
        <property type="entry name" value="DUF493"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117991">
        <property type="entry name" value="SSF117991"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="87" mass="9805" checksum="594E37AAE9F7154A" modified="2018-07-18" version="1">MSEDSLIEYPSDFPIKIMGAMHESFAQTMFELVLLHDPDFDAAKMEMRPSAKGTYLAITVTVRATSREQLDNLYRALSGHPMVKVVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0F1</accession>
    <name>A0A2S9H0F1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Rhs element Vgr protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1834</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93447">
        <property type="protein sequence ID" value="PRC93447"/>
        <property type="gene ID" value="S2091_1834"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006531">
        <property type="entry name" value="Gp5/Vgr_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006533">
        <property type="entry name" value="T6SS_Vgr_RhsGE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037026">
        <property type="entry name" value="Vgr_OB-fold_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04717">
        <property type="entry name" value="Phage_base_V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01646">
        <property type="entry name" value="vgr_GE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phage_base_V" evidence="1">
        <location>
            <begin position="377"/>
            <end position="451"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="596" mass="63198" checksum="5BA86418C76F947A" modified="2018-07-18" version="1">MANSPQTDSSGVLSFNISCDGTALPDIVQIVSIETNHSTNRIPTATITVIDGDMPNGSFPIADAGNLKPGVEIVISAGYDSKTTVIFTGVVIKHSVKISGDNYARLIIECRDKALAMTVGRKNANYINKTDNQVISALIAKYGGLSSAIDATSVSYKELVQYYATDWDYMMARAEINGFLVTIDAGKISVKAPVASGSPVLSLTYGMDLLEFQADLDSRWQLSSVTSTSWDLTQLAIVQKTATPDPLTGQGDIDSKTLAGVLSVGDFGLQTAAPIESGALTAWSKAQQTRAALSRIQGRMLFQGSALAKPGVLLELNAVGKHFNGNVIATNVTQRLIDGNWTTEVEFGMPTYWFTEEHQINAPEAAGISAGIGGLHIGIVLKLDADPEGQCKIQVSMPLMNASTIGVWARFASFYGSSGFGAFIIPEIGDEVVLGFFNNDPSCPVILGSLYSSKHVPPYELTAENNFKALVTRSKLKIEFDDGKKIITVTTPANNKIVISDEDKSILLQDENSNKVELSPSGILLDSPKDITIKAAGKVAISAVQNVEITAQMDVKTTGLNINSTANVSLIAKGTASAELSAAGQTTIKGAMVMIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0P1</accession>
    <name>A0A2S9H0P1_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 7">dTDP-4-dehydrorhamnose 3,5-epimerase</fullName>
            <ecNumber evidence="3 7">5.1.3.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Thymidine diphospho-4-keto-rhamnose 3,5-epimerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_1553</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 7">Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>dTDP-4-dehydro-6-deoxy-alpha-D-glucose = dTDP-4-dehydro-beta-L-rhamnose</text>
            <dbReference type="Rhea" id="RHEA:16969"/>
            <dbReference type="ChEBI" id="CHEBI:57649"/>
            <dbReference type="ChEBI" id="CHEBI:62830"/>
            <dbReference type="EC" id="5.1.3.13"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Carbohydrate biosynthesis; dTDP-L-rhamnose biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.1.3.13" evidence="3 7"/>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93552">
        <property type="protein sequence ID" value="PRC93552"/>
        <property type="gene ID" value="S2091_1553"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00124"/>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008830">
        <property type="term" value="F:dTDP-4-dehydrorhamnose 3,5-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019305">
        <property type="term" value="P:dTDP-rhamnose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000888">
        <property type="entry name" value="dTDP_sugar_isom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21047">
        <property type="entry name" value="PTHR21047"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00908">
        <property type="entry name" value="dTDP_sugar_isom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01221">
        <property type="entry name" value="rmlC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="62"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="5">
        <location>
            <position position="131"/>
        </location>
    </feature>
    <feature type="site" description="Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose" evidence="6">
        <location>
            <position position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00019595"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR600888-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR600888-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU364069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC93552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="181" mass="20809" checksum="6900EE1CFCD159BE" modified="2018-07-18" version="1">MKAITTSIPDLLILEPRVFGDDRGFFFESFNQRKFNELVGREVDFVQDNHSCSVKNVLRGLHYQIQQPQGKLVRVVQGTVFDVAVDIRKNSPTFGKHVSVELSAENKRMFWIPEGFAHGFVVTSETAEFLYKTTDYWNPEFERSILWSDPEIAIKWPNLGIPALSSKDLDAKLFADAEYFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0S7</accession>
    <name>A0A2S9H0S7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="9">ABC transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_1551</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ABC transporter superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93550">
        <property type="protein sequence ID" value="PRC93550"/>
        <property type="gene ID" value="S2091_1551"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03220">
        <property type="entry name" value="ABC_KpsT_Wzt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10147">
        <property type="entry name" value="Wzt_C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015860">
        <property type="entry name" value="ABC_transpr_TagH-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029439">
        <property type="entry name" value="Wzt_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14524">
        <property type="entry name" value="Wzt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-1278">Translocase</keyword>
    <feature type="domain" description="ABC transporter" evidence="8">
        <location>
            <begin position="31"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="68"/>
            <end position="75"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC93550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="460" mass="50993" checksum="24AD097986025E17" modified="2018-07-18" version="1">MNEIAIQVENLSKCFQVYSSPRDRLKQFIFPRLRRLFGKSSKHYFDEFWALKEVSFQVKKGETVGIIGRNGSGKSTLLQMICGTLNPTGGTIQTYGRVAALLELGAGFNPEFTGRENVYLNATVLGLSKAEIDARFDDILAFADIGEFVEQPTKTYSSGMMVRLAFAVAINVDPEILIVDEALSVGDELFQRKCFSRIEAIRASGATILFVSHSGSTIVDLCDRAVLLDAGEKLAIGVPKQIVGRYQKMLYAPADKYDAIREQIRHADDYVISAIDNSKNEINDAIEERLSTKHITEIRENFDFNLKPSSTIEYESRGVNIGMPAILNISGEQVNNLVRGKVYRYAYNVKFSSSASSVRFGMMIKTTSGVELGGGISAHAVKTSIAFVDADSSYRVEFRFCCSLNPGVYFLNAGVLGDVNGNETYLHRVVDFAMFRVLPESEDLATGVVDFFCYPELELQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0Z3</accession>
    <name>A0A2S9H0Z3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Glycosyl hydrolases related to GH101 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1650</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93649">
        <property type="protein sequence ID" value="PRC93649"/>
        <property type="gene ID" value="S2091_1650"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021459">
        <property type="entry name" value="GH101-related"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11308">
        <property type="entry name" value="Glyco_hydro_129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="735" mass="81950" checksum="3F222EB352A65151" modified="2018-07-18" version="1">MPPPYFIRLATYFLLFILLLPLSGQALTLSSPDWLIEIDPATLSATAQLPDGQRLVISSAQNTDRVMSLKNSASEASWRLGDTGIQVNARLDGHKLIVRFSSSTTSVMQWPLIPSGARGLILPLAEGNYIPAQHSIWRDALAGDYNDIDTTEGLSLPVLGLDHGDQVLSVLFINPFHNRLHFTPEPNGIALVAEHRFTSPAPYEIQISLNDANWLAPALEYRKWLKAQGRFISLESKLAAAQDGEALIGASHAYLWGSRLLALTDVRDWRGLQTRLKKLPRLIGKFDDVGQQALRQLATSNEVWLQRVLIDNLNTALESRFAGNDVQTIRQRKNYAIQQFGEVLINPERWGEGASTKMIAALQQAGLSRLWLGLPQWEAGYAHPEAIAAARLAGYLIAPYDSYNTALPDNGNQDWSSSHLGQDAFERCGIMQDDGQRRSGFQGEGVYTNSACIRPILEQRVRDIQYESGYNSWFIDADASGMLFDDMDPAKPTSQAQDAESRQAGMAWISNNLGLVVGSENGHATVNRSIAFAHGLQTNGFGWRDPDMRNNSASPYFMGRWFPESQPQVFFRAAAIKPVYRALYFDPATRLPLFQAAFHDSIITTHHWLIDSLKFPETRQTTELLAQLYNVAPLLNLSLDTNAERLPYLKHLDDFFRPLHQRLAFQALTKFSWKNADGQVQETRFADGTRIVANFSSKLYDDGTLKVPGLSVLASMPDGTVSRFQSEMMNIKPTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H197</accession>
    <name>A0A2S9H197_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1739</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93738">
        <property type="protein sequence ID" value="PRC93738"/>
        <property type="gene ID" value="S2091_1739"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018931">
        <property type="entry name" value="DUF2520"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019665">
        <property type="entry name" value="OxRdtase/DH_put_Rossmann_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037108">
        <property type="entry name" value="TM1727-like_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10728">
        <property type="entry name" value="DUF2520"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10727">
        <property type="entry name" value="Rossmann-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rossmann-like" evidence="1">
        <location>
            <begin position="5"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="domain" description="DUF2520" evidence="2">
        <location>
            <begin position="134"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF10727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="270" mass="28962" checksum="E7925A1347D9D90B" modified="2018-07-18" version="1">MKPTLSIIGAGKVGRVLGQQFFKHHIFTLHDVLNRSLSSSLAACKFMGAGNAISEFSELRQADVYMLAVSDDQIKSCSQQLQQLGLINPDTLVFHCSGALCASELGMTNGAASLHPIRSFADPTTVAAQFTDTICSVEGNANAAQILTTALEKMGAQVVHLEPEGKALYHAAAVFASNYLVTLMDAALTTFQAAGIPLKMAQHMTEPLARETLENVFRLGAKNALTGPIARGDFLTVKRHHDALNSTNPDNAELYMALAESTKQMKDRDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1B9</accession>
    <name>A0A2S9H1B9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1393</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the BlaI transcriptional regulatory family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93784">
        <property type="protein sequence ID" value="PRC93784"/>
        <property type="gene ID" value="S2091_1393"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005650">
        <property type="entry name" value="BlaI_family"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34134">
        <property type="entry name" value="PTHR34134"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03965">
        <property type="entry name" value="Penicillinase_R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="127" mass="14407" checksum="D445F7A7C5D3E582" modified="2018-07-18" version="1">MTKNIPIPKPTTVEMNVLRLVWQLGPSTAKQVLQEAVKERPEITYATILRVLQIMHSKGLLIRDESQRSHIYAPAQPQDALQSNLVKDLIQKVFAGSGKALVMEALRTHVSKKERDEIEALLREDKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1G3</accession>
    <name>A0A2S9H1G3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Biopolymer transport protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_1433</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the ExbD/TolR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93824">
        <property type="protein sequence ID" value="PRC93824"/>
        <property type="gene ID" value="S2091_1433"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003400">
        <property type="entry name" value="ExbD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30558">
        <property type="entry name" value="PTHR30558"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02472">
        <property type="entry name" value="ExbD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC93824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="132" mass="14201" checksum="19D93C4C0DEE2CA2" modified="2018-07-18" version="1">MRYLETKKARIEIIPMIDIMLFLLVFFAMLTLRMIPASGHVTKLPTSSTAATIPPPKLLVEITADGSLLVETKVLNAEQLTTLLRQRGSSKTAVTIAGNETATLQQVMSVIDAIKLGGATEIGIATRHDAGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1M6</accession>
    <name>A0A2S9H1M6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Type III secretion low calcium response chaperone LcrH/SycD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1477</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LcrH/SycD chaperone family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93868">
        <property type="protein sequence ID" value="PRC93868"/>
        <property type="gene ID" value="S2091_1477"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005415">
        <property type="entry name" value="T3SS_Ca_resp_chp_LcrH/SycD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016379">
        <property type="entry name" value="T3SS_Ca_resp_chp_LcrH/SycD_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011716">
        <property type="entry name" value="TPR-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07720">
        <property type="entry name" value="TPR_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003165">
        <property type="entry name" value="Chaperone_SicA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01595">
        <property type="entry name" value="SYCDCHAPRONE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02552">
        <property type="entry name" value="LcrH_SycD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="187" mass="21026" checksum="EEAF5BE9CE67FC2E" modified="2018-07-18" version="1">MFVFLMRLQGVYLILALSVDDAKGICGMSHQDEETAEQDLEVILDAVNQGVTLKEIHGISDEQMDGLYSLAYDFYNQGRLDEAEKFFRFLCIYDFYCVDFLMGLAAVYQLKEMYQKAADIYAIAFAQGDADYRPMLYSGQCQLAMGKSGKAKQCFKVVVEQSDDDALKAKAQAYLTALQRSRTSGSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1Q9</accession>
    <name>A0A2S9H1Q9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1533</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93924">
        <property type="protein sequence ID" value="PRC93924"/>
        <property type="gene ID" value="S2091_1533"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="141" mass="15448" checksum="37C2ADB5E0BFBE0E" modified="2018-07-18" version="1">MAISPLSVQQIVAVIRQQMTDPIRTMSTSVPMSAPGVVRKGAGTRSQTTKVKQGGLSKMIGHRVNALQVTDPERGRKAFRIFLESVLINELGEDLINDPSFYQMVDDIQVQMESNPDIAKAMREATDQLLSGVDPLKNAPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1X6</accession>
    <name>A0A2S9H1X6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Methyltransferase domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1140</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC93967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93967">
        <property type="protein sequence ID" value="PRC93967"/>
        <property type="gene ID" value="S2091_1140"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="285" mass="31547" checksum="16CFB28E38372F04" modified="2018-07-18" version="1">MQKIFNKFFSRKQTTQLTPPISNELQKLAVPASGALEANPFEIGLKDAGHDGWYRVESGELYAGFLIDADDVVVDVGCGDGGSALFCANRGAHVIFADIDPDKVAATTHRLAGTPARCIQGVVSDANPLLLGDGVASKVISMEVLEHVDDTAQFLSELVRIGKPGAQYLITVPDPVAEQLQVGLAPDVYFQKPNHVRIIQRDEFEKMVTDAGLVIESHSYYGFYWSIWWMFFWVCKVDLSNPQHPLLNSWARTWEALSDQPMGDQLRKSMNALMPKTQVIVARKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H247</accession>
    <name>A0A2S9H247_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">STAS domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1186</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94013">
        <property type="protein sequence ID" value="PRC94013"/>
        <property type="gene ID" value="S2091_1186"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13466">
        <property type="entry name" value="STAS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SSF52091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="STAS" evidence="1">
        <location>
            <begin position="7"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="84" mass="9086" checksum="15A3E8696E1084F6" modified="2018-07-18" version="1">MSFTPTSVFTHENATQQLAAGLAAIDAGQSAFAFNQTNSIDSSAVACMLAWQRHAQQRGVKLEFQQLPINLTNLIALYGVAEFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H293</accession>
    <name>A0A2S9H293_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1272</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94099">
        <property type="protein sequence ID" value="PRC94099"/>
        <property type="gene ID" value="S2091_1272"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="27"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="108"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="146" mass="16015" checksum="BFDFA9DA09C35439" modified="2018-07-18" version="1">MLSEKNDENAVQKVIENEQLVNRLRRIGFGILIVGLLSAIAVFIFASTANNADGNVVAYENIGGVSYPVDASSSKGYQYNVERVGGKSTLLAVELDDWFASLWHGKKLSYTLAFLSICSALGCFLLARLFSLPPHEDEVDNQDWKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2E0</accession>
    <name>A0A2S9H2E0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_1324</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94151">
        <property type="protein sequence ID" value="PRC94151"/>
        <property type="gene ID" value="S2091_1324"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="3">
        <location>
            <begin position="2"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="4">
        <location>
            <begin position="124"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="2">
        <location>
            <begin position="124"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC94151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="224" mass="24983" checksum="195F85C3C5678C56" modified="2018-07-18" version="1">MKLLLVEDNRELSTWLTRLLQASGYTIEQAFSGEEAMLLLRTQCYDAILLDITLPKINGQTILKNLRSKNNEVPVLIISASAALGDMVENLNLGADDYLAKPFDIAELEARIRSLLRRASGKLNPIISCGNLRYDSNSKIFSSQSFDLNLTPREHAVLEALMRQAGKTVDKKQLANSLCTLNDSISPKALEIYILRLRKKIDHSGAQIITLRGLGYMLSYVQTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2J6</accession>
    <name>A0A2S9H2J6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="9">GGDEF: diguanylate cyclase (GGDEF) domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_0820</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94199">
        <property type="protein sequence ID" value="PRC94199"/>
        <property type="gene ID" value="S2091_0820"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033479">
        <property type="entry name" value="dCache_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02743">
        <property type="entry name" value="dCache_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="25"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="362"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="7">
        <location>
            <begin position="421"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="8">
        <location>
            <begin position="495"/>
            <end position="631"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC94199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="649" mass="72157" checksum="97C78A5FB7B5772C" modified="2018-07-18" version="1">MAPLLSLLIALNTHLKKYTYSLRQFLALPFLALFFLMVAVLVGMFFYNSVSMGRQMEQQLALVLNGRVNLYLGQIFSEPVTAVNTINRLYRSGKLRSGGVEDQARQIATVMSTLPELTVLNFGLEDGRHIGVNRSLNNGALHTSVVMSSAKPYRDVYSVTEDGQRDLFIFTDPNPFIPSMRPWYQSAVQHGKASWYPIYRYVASEIADVIGNFGIGYSMPVYDEKGKLFGVINSDIALGQISRYLRLLPLGEGGVAFIANDQNQLIGISNDTPLFRKQENVKEGATNLQLIHFNNNDSPLIRAAGDRLLQSGVGSSYLNLNGANYVEDVREFKTNSGLTLKVVVLLPETQFFPAIQSDIKSMLIFVLFALAIGVALVFIVAFRLSKPMVQITHWAEQLAQGNWELLRKTNNKGMRDYPIKEIRQLRKSFADMAASLHETVATLEQRVAERTAELELVNSNLSELSNTDGLTGIPNRRKFDAVLANEWSRATRTGQPLVLALIDIDWFKKYNDHYGHLAGDDCLRNVANILKAKIRRSSDLVARYGGEEFAIIAPAINKANAVEMANLICSTLAEACLPHAMSPFEVITASIGVALIVPTVEINPETLIQAADEALYHAKDSGRNQVICAEIEIAGEEQFFETEFKFEQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2Y6</accession>
    <name>A0A2S9H2Y6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0847</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94226">
        <property type="protein sequence ID" value="PRC94226"/>
        <property type="gene ID" value="S2091_0847"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="39" mass="4463" checksum="BF8C94301B56EA2F" modified="2018-07-18" version="1">MLLHYHPKTIKISNKFSRVVLPVVGVYWVSGEGYCRTAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H321</accession>
    <name>A0A2S9H321_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0954</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94333">
        <property type="protein sequence ID" value="PRC94333"/>
        <property type="gene ID" value="S2091_0954"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="91" mass="10385" checksum="101583C551ADE80D" modified="2018-07-18" version="1">MSSIKLFMPSGGEDGVIIAIRDDDVRVEFRGSPYSKWNVNESSPMYQLHSSLRRIDISQLHNGEIEVVTPWHPEWKIVSELFDTALQIGNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H379</accession>
    <name>A0A2S9H379_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1014</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94393">
        <property type="protein sequence ID" value="PRC94393"/>
        <property type="gene ID" value="S2091_1014"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="101" mass="11390" checksum="73C5A9CFDA02FA47" modified="2018-07-18" version="1">MTSTDQIHTQQRPPLITHLAVDTIDAYTQARDIVSDLSAIFEVLDHLALEGLCTDRISRILFQAGICHATERLKFIDERITDAYKTLDELKADSGNNFNTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H392</accession>
    <name>A0A2S9H392_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein conserved in bacteria (DUF2059)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_1048</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94427">
        <property type="protein sequence ID" value="PRC94427"/>
        <property type="gene ID" value="S2091_1048"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018637">
        <property type="entry name" value="DUF2059"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09832">
        <property type="entry name" value="DUF2059"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015742577" evidence="2">
        <location>
            <begin position="22"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="domain" description="DUF2059" evidence="3">
        <location>
            <begin position="95"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="165"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="165"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF09832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC94427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="192" mass="21334" checksum="F265FFF3736910DF" modified="2018-07-18" version="1">MKKLFGFIAALTLLASSQVFAQTTKPTQESLQKLFEITEVSSMIPKLQSQLEAAVNHLVQEAMKGKTITPDQQKALDAFRAKIIKIQNDEISWNAMEPRIAEIYGNTLSQADVDGMIAFYQSPAGISFSKKMPEIMQQTMNMMQKMMGPLMEKMGAAQAELAQDLKPEVKSDVKPEVNPDLKPELTQASPQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3F5</accession>
    <name>A0A2S9H3F5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0515</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94512">
        <property type="protein sequence ID" value="PRC94512"/>
        <property type="gene ID" value="S2091_0515"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="302" mass="34700" checksum="CE66DE42FF49D178" modified="2018-07-18" version="1">MSLIATQKKSIWTRHAIVLVMIFLISAMPVFAEQTSAPSTVLFYPRPEINDDSRGVFPLHVLQLALSKVTTKYTLTPTNSVMDQDRALLQMETPNGGMDVVWTMTSIDRESRFTPIRIPIDKGLIGWRLPIISQKDPEKLKPVFSVNDLKKFIACQGHDWPDTSILRANGLRVMVDPHYQNLFRLVAEAQADYFPRSTLEIWNELDAHKTEGLMLDPYLVINYHAAMYFFVNKSNQKLADDITKGFEKAIADRSFERLFQSEYGEKIRKANLSSRRLIHIENPFLPAATPINRKELWFIPPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3G8</accession>
    <name>A0A2S9H3G8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="10">TonB dependent receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">S2091_0513</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94510">
        <property type="protein sequence ID" value="PRC94510"/>
        <property type="gene ID" value="S2091_0513"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="3 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 10" id="KW-0675">Receptor</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="2 6" id="KW-0798">TonB box</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015717733" evidence="7">
        <location>
            <begin position="30"/>
            <end position="975"/>
        </location>
    </feature>
    <feature type="domain" description="Plug" evidence="9">
        <location>
            <begin position="58"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="8">
        <location>
            <begin position="363"/>
            <end position="973"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC94510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="975" mass="103964" checksum="CF901C462133E162" modified="2018-07-18" version="1">MNCEFKVIVTAVRVALTLLASTTLMTAHAQQVANTDTDADTNVKKVIITGSNIKTVDSETASPVQIIKREDITRQGVTNVSDLIANLSSSTNPNNPNSGLTDIAGNNTFAPGSSSASLRNLGEQSTLVLVNGRRIATYGFANFTDVFSNVDTIPIDAIDRVEVLKSGASAIYGSDAVAGVINIITRTNYQGVDVSADRTSSLQSHTFNTNKASITAGFGDLNEDGFNVMVNADFFKRDSVNWNGLINYTNQSLTASSADFGQFSGYSNPGNILDGANTQPRPGCAPNLITNGLCTWDRYSGTQVVPESDRQNYYASGTFNLGGGTQAFAEALLSKSKTYYSSRNDTFGSSPTPIIWANPTTGQPLTFNYLGLPATSPINPTGDAGAGLLYRFTDVPNINNIDGTQFRVLGGLRGSVGSYEWETAAGITQSKVTSAQQGGAFSSSGFISEIGDYNNFNPNVINPNVGAYTANDPNFFNQPNGYHLGGGNSPAVLNTLFPVFSNTGKTQAEFVDAKINGPLYTLPAGPVYFNLGGELRHESMNLGVSQNLQDGDIVGYGISTASASRNIESLYSELNVPVIKDMELSPALRLDKYPEISTHFSPKIGWRFKVADSLLLRATYEQGFRAPNLVESATSLKTAFAPGIADPLRCAQASALANDLGNAGNSAVISAKQQQVIQNECSNSIPEAVLNNPNLKPETSKSFSFGLVFEPVKGYSTSLDYWHIDRSNTIGLPSAQQVITNAASGVATPGSNVNRAPFNPNGDQTFSANDGLLGGQNDFTKYGVTAGPILNMSQSLENISEQSTSGVDIALKATQSIGTWGKLSGVLDGTYTISYYDTSISTASENLVGQYGFPHMVANFTAIWDFQSFSNSLRYNYTGGYDSQQGQSDTTWSIAGCASSGFSATQCRVASNRTTDYALSYTGIKNLALGLNIINIFQQKAAPDFRAFGQDGLFPPNTQDAMGRMLRLSLNYKFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3L9</accession>
    <name>A0A2S9H3L9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acetyltransferases including N-acetylases of ribosomal protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0564</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94561">
        <property type="protein sequence ID" value="PRC94561"/>
        <property type="gene ID" value="S2091_0564"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="9"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="181" mass="20560" checksum="6D215FE9D1A5622B" modified="2018-07-18" version="1">MTILTTKRLRLEPFADHHLDGLYALNSDPEVMRYITGKPQALEETKAGIAMIKERWLNTGFSWWSFIELATGEIIGAGCIQYLARDPANPHEIGWRLRQNKWGQGFASEAAQCMAAFAFDTLDVELLCAICDPENTKSTRVMRGLGMQYRGIEHWNDEDVAAYYLSRAEYELKKTVIPPIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3T1</accession>
    <name>A0A2S9H3T1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Bacterial extracellular solute-binding protein, family 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_0647</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94644">
        <property type="protein sequence ID" value="PRC94644"/>
        <property type="gene ID" value="S2091_0647"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001638">
        <property type="entry name" value="Solute-binding_3/MltF_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00497">
        <property type="entry name" value="SBP_bac_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015698695" evidence="2">
        <location>
            <begin position="21"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="domain" description="PBPb" evidence="3">
        <location>
            <begin position="27"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC94644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="69" mass="7525" checksum="809666B8BCB5CBE4" modified="2018-07-18" version="1">MKLIKATILFCLCAYLQLVAAQTRPLVIVAEDYAPATFMDKGNVTGFDVDIAKAVFDSLGISYEIKLVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3W2</accession>
    <name>A0A2S9H3W2_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">UPF0056 membrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_0678</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the UPF0056 (MarC) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94675">
        <property type="protein sequence ID" value="PRC94675"/>
        <property type="gene ID" value="S2091_0678"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002771">
        <property type="entry name" value="Multi_antbiot-R_MarC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33508">
        <property type="entry name" value="PTHR33508"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01914">
        <property type="entry name" value="MarC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00427">
        <property type="entry name" value="TIGR00427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="52"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="82"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="114"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="146"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="191"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC94675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="215" mass="22871" checksum="462EB564F54B68DE" modified="2018-07-18" version="1">MSGLLELLEVVSLGMMAILPLANPLTTVALLLGMSGNRSHAELHRLSRMTSIYVFMIMLVAFYGGQIVMTTFGISIPGLRVAGGLIVAYIGFRMLFPVPAPAAGTNQDELSADIAFIPLAMPSTAGPGTIAMIISGAATFKDLTNITPWVLTVAPVLVFIGVSLVLWISLRSAKTIMRFLGRSGIEAVSRLMGFLLICMGVQFVINGIVEITRSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3W5</accession>
    <name>A0A2S9H3W5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0663</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94660">
        <property type="protein sequence ID" value="PRC94660"/>
        <property type="gene ID" value="S2091_0663"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="5"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="303" mass="34055" checksum="7BDC137C159F8616" modified="2018-07-18" version="1">MTTSIDLRQFRYFLALCEELNFGRAAERLNISQPPLSRQIRQMEDQLGVELFHRNPTGVTLTAAGSAFLPEVRRTLQQAAKAIAAARAAGNVDGGQLRIGYTTVFDRSAIPDVSEQFHNLFPSWRLVTKGKHSIALIRDINNGNMDAAFIGMHTDAKGLNVETIREEPLMVALPANHKLAKKRKLGFDDLRNEPLFWFERRLNPGFYDYSQAFFERVNFKPTVIPEPPDHHILLGQIANGQGFALIPASLQNVKRQGVVFRDLKDEFKNLSMEIAIAYSAQNQSPVLRSFLELVRANASNPVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3W9</accession>
    <name>A0A2S9H3W9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NAD-dependent aldehyde dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_0569</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94566">
        <property type="protein sequence ID" value="PRC94566"/>
        <property type="gene ID" value="S2091_0569"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016620">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
        <property type="entry name" value="ALDEHYDE_DEHYDR_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldedh" evidence="3">
        <location>
            <begin position="32"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC94566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="495" mass="53564" checksum="450E5592C93402CF" modified="2018-07-18" version="1">MSTRLWHDRATSIQIDGRAFINGERVHAVSGATFENTSPVNGRKLCHVARCDSEDVNLAVLAARTAFEDRRWAGKSPAERKRVMLKFAELMRANRDELALLETLDMGKPIKYSLSVDVPSAARCIQWYAEAIDKIYDEIAPTNDATLALITREPVGVVAAIVPWNYPMLMASWKIAPALAMGNSVILKPSEKSPLSALRMAEIALEAGIPAGVFNVLPGFGHEAGSALALHNDVDCIGFTGSTRIGKKIMEYAGQSNLKRVWTELGGKSPNIVCADCPNLDEAVEAAIGSIYFNQGESCNAPSRLFIEESIKDKFIEKALAMLPAYVPGDPLDPATVMGAIVDNIQLNSVMGFIESGKAEGATLLAGGNQVRAESGGYYIEPTIFSNVTNSMKIAREEIFGPVLSIFTFTDLNDAIQAANATAYGLQAGVWTSDIRKAHHAARALRVGTVHVNQYDGDDITVPFGGYKQSGNGRDKSLHALDKYTELKTTWINLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H440</accession>
    <name>A0A2S9H440_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative addiction module killer protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0639</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94636">
        <property type="protein sequence ID" value="PRC94636"/>
        <property type="gene ID" value="S2091_0639"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014056">
        <property type="entry name" value="Addiction_killer_pred"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014057">
        <property type="entry name" value="HI1420"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41791">
        <property type="entry name" value="PTHR41791"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02684">
        <property type="entry name" value="dnstrm_HI1420"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02683">
        <property type="entry name" value="upstrm_HI1419"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="194" mass="21554" checksum="68BA714CFA81E62C" modified="2018-07-18" version="1">MIELKQTEIFRKWRLQLKDDKVRALIASRLDRLSFGHAGDAEPIGQGISELRIHYGLGFRIYFQKRGNTIIVLLCGGDKSSQAKDIKTAKKLAAEWSEKMTEKLTTYDPAEDLSSDEAMAIFMTEAFETNDASYIAHALGVVARAKGMAQIAVQTGLSREQLYRSFSENGNPTLKTTLAVMKALGLDLTAKVHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4E5</accession>
    <name>A0A2S9H4E5_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">N-acetylmuramic acid 6-phosphate etherase</fullName>
            <shortName evidence="2">MurNAc-6-P etherase</shortName>
            <ecNumber evidence="2">4.2.1.126</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">N-acetylmuramic acid 6-phosphate hydrolase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="2">N-acetylmuramic acid 6-phosphate lyase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">murQ</name>
        <name evidence="4" type="ORF">S2091_0033</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>H2O + N-acetyl-D-muramate 6-phosphate = (R)-lactate + N-acetyl-D-glucosamine 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:26410"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16004"/>
            <dbReference type="ChEBI" id="CHEBI:57513"/>
            <dbReference type="ChEBI" id="CHEBI:58722"/>
            <dbReference type="EC" id="4.2.1.126"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-sugar metabolism; 1,6-anhydro-N-acetylmuramate degradation.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-sugar metabolism; N-acetylmuramate degradation.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cell wall biogenesis; peptidoglycan recycling.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="2">A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.126" evidence="2"/>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94838">
        <property type="protein sequence ID" value="PRC94838"/>
        <property type="gene ID" value="S2091_0033"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00342"/>
    <dbReference type="UniPathway" id="UPA00343"/>
    <dbReference type="UniPathway" id="UPA00544"/>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097367">
        <property type="term" value="F:carbohydrate derivative binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016835">
        <property type="term" value="F:carbon-oxygen lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097175">
        <property type="term" value="P:1,6-anhydro-N-acetyl-beta-muramic acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046348">
        <property type="term" value="P:amino sugar catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097173">
        <property type="term" value="P:N-acetylmuramic acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009254">
        <property type="term" value="P:peptidoglycan turnover"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd05007">
        <property type="entry name" value="SIS_Etherase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00068">
        <property type="entry name" value="MurQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005488">
        <property type="entry name" value="Etherase_MurQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040190">
        <property type="entry name" value="MURQ/GCKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001347">
        <property type="entry name" value="SIS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046348">
        <property type="entry name" value="SIS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10088">
        <property type="entry name" value="PTHR10088"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10088:SF5">
        <property type="entry name" value="PTHR10088:SF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53697">
        <property type="entry name" value="SSF53697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51464">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="1 2" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SIS" evidence="3">
        <location>
            <begin position="51"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="2">
        <location>
            <position position="79"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC94838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="293" mass="30858" checksum="7B738996378194A3" modified="2018-07-18" version="1">MPTTESPNQQHSELDLYSVEKLIDVFVEDQLNAVYAVQASSAQIAQAVAASVPRMELGGRLIYVGAGTSGRLGVLDSVELQPTFSWPIERAVGLLAGGHSAMFVAVEGAEDDALQGALDIEANAVSELDVVLLLAASGSTPYVMGALHAAKEKGALTVGIVNNINTPLALLAEIGIVLETGSELISGSTRLKAGTAQKIALNSFSSALMIRLNKTYGNLMVDLKPNNAKLHLRAIHLTMLACDCDASTANNMLHECDFEIKVAIVALQKNESISAAKKRLAEANGNVRLALKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4I2</accession>
    <name>A0A2S9H4I2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0089</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94894">
        <property type="protein sequence ID" value="PRC94894"/>
        <property type="gene ID" value="S2091_0089"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015504702" evidence="1">
        <location>
            <begin position="37"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="144" mass="16136" checksum="92A9EC67729A23A0" modified="2018-07-18" version="1">MNNCLKNCIQSSLLRSFFSICSTLLFSFTLISTSYADDSTYRTELNRTDFSGTPNMEIVSSIVEFKPGDFVHKHFHHGVESAYVLQGAMIQEPGKKPRMLATGTPLLNQRDVMHGGFTIVGDTNLKIFTVHVVDKNKPLYDEGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4M9</accession>
    <name>A0A2S9H4M9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative NADP-dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0113</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94918">
        <property type="protein sequence ID" value="PRC94918"/>
        <property type="gene ID" value="S2091_0113"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016628">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041694">
        <property type="entry name" value="ADH_N_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045010">
        <property type="entry name" value="MDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43205">
        <property type="entry name" value="PTHR43205"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16884">
        <property type="entry name" value="ADH_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PKS_ER" evidence="1">
        <location>
            <begin position="15"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="336" mass="35946" checksum="07BA07AE1625682C" modified="2018-07-18" version="1">MNQNHQFKLTSRPVGAVKRSDFSYTQEPVRDPADGEVVIKNLYISLDPAMRGWMNESKNSYIPPVAIGEVMRALAVGRVVASKNPQFTVGDHVGGMLGMQEYAYSNGQGLNKVDPRMAPLPVFLGTLGMPGLTAYFGLLDVGKPKEGETVVVSGAAGAVGAVVGQIAKIKGCRVIGIAGGAEKCRYLVEELGFDAAIDYKKEDVKAALHQHCPQGIDVYFDNVGGEILDAVLTRLARNARIVICGAISQYNNTTAVQGPANYLSLIVARASMQGIMVADYYPRAMEALSAMGGWLASGKLKSREDIVDGLETFPDTFLKLFSGENNGKLVLKVAEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4W1</accession>
    <name>A0A2S9H4W1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Histidine phosphatase superfamily (Branch 1)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0217</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95022">
        <property type="protein sequence ID" value="PRC95022"/>
        <property type="gene ID" value="S2091_0217"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="SSF53254"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0312">Gluconeogenesis</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC95022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="236" mass="26583" checksum="5DF0D4EAB2A6F9D7" modified="2018-07-18" version="1">MDAIYLVRHGQASFGSANYDQLSELGVRQSLLLGQWMRQSQQSVETLVLGGMQRHHQSAEAFVEGFGSPEHLHPQHWLVEPGFNEFDHEQILHRSRPEFADSLQLMQFLASQDQPRSVFERMFSDALARWMNGENDVDYVESWSAFQTRVSCSLKALTTEKLITQNTIVFTSGGPISVACQQLLAVPDTHLMQLMVGMVNSGVSKLLHSDGQINLASMNTIAHLELHNDQSLITYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4Y7</accession>
    <name>A0A2S9H4Y7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Tfp pilus assembly protein PilX</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_0247</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95052">
        <property type="protein sequence ID" value="PRC95052"/>
        <property type="gene ID" value="S2091_0247"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025205">
        <property type="entry name" value="PilX/PilW_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025746">
        <property type="entry name" value="PilX_N_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13681">
        <property type="entry name" value="PilX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14341">
        <property type="entry name" value="PilX_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="24"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="domain" description="PilX_N" evidence="3">
        <location>
            <begin position="20"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="domain" description="PilX" evidence="2">
        <location>
            <begin position="106"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF14341"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC95052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="213" mass="22838" checksum="0DBF1F0FB31E3873" modified="2018-07-18" version="1">MLSPAHHHCKHSITSFHHQRGASLIVSLVMLLVLLMLGISLANIALMGEKAARNDRDRQIAMQAAEAALTDAEMDIENSSRSVIFSPDSSEGFTDLCGKGDSNIYQGLCTYNGDRKTAAWLTADIANTSGTAASVKYGRFTGKTMPSGAGPFPNKLPRYLIELMMDTAPGQEVKAAYIYRISAVGFGTNSSTQVVVQSFYRKADSVPAAASQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H531</accession>
    <name>A0A2S9H531_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Efflux transporter, RND family, MFP subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_0273</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95078">
        <property type="protein sequence ID" value="PRC95078"/>
        <property type="gene ID" value="S2091_0273"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043602">
        <property type="entry name" value="CusB_dom_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006143">
        <property type="entry name" value="RND_pump_MFP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00529">
        <property type="entry name" value="CusB_dom_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01730">
        <property type="entry name" value="RND_mfp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015478983" evidence="2">
        <location>
            <begin position="24"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="domain" description="HlyD_D23" evidence="4">
        <location>
            <begin position="69"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="domain" description="CusB_dom_1" evidence="3">
        <location>
            <begin position="304"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC95078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="388" mass="42071" checksum="AA3A3A9B7F159BF5" modified="2018-07-18" version="1">MHSIQWRNVAPLFLLITSLVLSACSTEDASNTKTTAVPAEAENDTALKLSEEEIKTAGIQVATLQEQQINEQILVTATIQPNQNKVAQIAPSVAGKVRTALVNLGDQVKQNQPLASIDSIEAGEAQSAYEQAKSEFTLAQSSFDRAKQLVADRIIPQKDYLRAQSDLEKARAGLQATSTKLQTIGIAPQNQRSNSSLFMVSAPFSGTVIVKNAVVGELAQPDKALFTIADLSKFWIETNLFEKDFSKVKVGAPATITSTAYPGELFKGKVTYIGNMVDKETHTANARIEVINLDDRLKLNMFVNAAIETSSTQKALLLPEQAIVLIQGQSTVFVQTEHGFEPRAVELGEKLHTQVVLKNGINSGEKIVTIGTYALKAKILKSQISAEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5L9</accession>
    <name>A0A2S9H5L9_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 14">Undecaprenyl-diphosphatase</fullName>
            <ecNumber evidence="4 14">3.6.1.27</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13 14">Bacitracin resistance protein</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12 14">Undecaprenyl pyrophosphate phosphatase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">uppP</name>
        <name evidence="15" type="ORF">S2091_0418</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 14">
            <text>di-trans,octa-cis-undecaprenyl diphosphate + H2O = di-trans,octa-cis-undecaprenyl phosphate + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:28094"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58405"/>
            <dbReference type="ChEBI" id="CHEBI:60392"/>
            <dbReference type="EC" id="3.6.1.27"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="14">Cell membrane</location>
            <topology evidence="14">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="14">Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the UppP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.27" evidence="4 14"/>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95223">
        <property type="protein sequence ID" value="PRC95223"/>
        <property type="gene ID" value="S2091_0418"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050380">
        <property type="term" value="F:undecaprenyl-diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016311">
        <property type="term" value="P:dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046677">
        <property type="term" value="P:response to antibiotic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01006">
        <property type="entry name" value="Undec_diphosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003824">
        <property type="entry name" value="UppP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30622">
        <property type="entry name" value="PTHR30622"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02673">
        <property type="entry name" value="BacA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 14" id="KW-0046">Antibiotic resistance</keyword>
    <keyword evidence="6 14" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="14" id="KW-0133">Cell shape</keyword>
    <keyword evidence="14" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="8 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="46"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="75"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="118"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="228"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="263"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010621"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00021581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00032707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00032932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="PRC95223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="281" mass="30455" checksum="ABCC534F45282275" modified="2018-07-18" version="1">MDLFQILILAVIQGAAELLPVSSSAHVIMAEKMMGLDPTSPEMTLLLVMLHTGTMFATIVYFWSSWKKTYFESIAAFRLNVLYLVAATGLTGIVGYGLQQIIKYVFVANPSEFEIEHLFGSAPLMATALASAGLLIIGSSRIKEKPEGQMSLRSALIIGAVQGLCLPFRGFSRSGATISTGLVVGVARRKAEEFSFALGVAITPAVVAREAYRVYQAQLAVPAAHTDWIMHLAMPSLLGLVFSFLAGLVALRWLSRWLEQGRWYFFGGYCLVAAVVVLVVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GS96</accession>
    <name>A0A2S9GS96_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Poly-beta-1,6-N-acetyl-D-glucosamine N-deacetylase PgaB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_4691</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000045">
        <property type="protein sequence ID" value="PRC90602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90602">
        <property type="protein sequence ID" value="PRC90602"/>
        <property type="gene ID" value="S2091_4691"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043708">
        <property type="term" value="P:cell adhesion involved in biofilm formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002509">
        <property type="entry name" value="NODB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023854">
        <property type="entry name" value="PGA_deacetylase_PgaB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032772">
        <property type="entry name" value="PGA_deacetylase_PgaB_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14883">
        <property type="entry name" value="GHL13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01522">
        <property type="entry name" value="Polysacc_deac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="SSF88713"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03938">
        <property type="entry name" value="deacetyl_PgaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51677">
        <property type="entry name" value="NODB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015727823" evidence="1">
        <location>
            <begin position="40"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="domain" description="NodB homology" evidence="2">
        <location>
            <begin position="127"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC90602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="695" mass="79106" checksum="4BDE43998B8375B7" modified="2018-07-18" version="1">MNWLFISHLMMVARTSLHTQRAACMMLVVALLSTGIASAQTVELSSAEQLLTAVPAANDPPQSFRVLCYHDIRDNLQETFKTQPEATAVDTIELIRHFSWLKENGYHPVSLQQIIDARAGHGTLPDKAILLTFDDGYKSVFTKVFPLLKLFNFPAVIAIVGDWIETPPNEQVLFGDKLLARDQFANWEDIRTMVASGLVEVASHTNNLHKGIMANPQGNSFPAAISRYYRPQNSSYESNDEYSERIQLDLQRNSELIEHQLHKMPRAMVWPYGRYNQETTQLAAKMGMPITMNLDSGPNTPDQPLARMRRTLINFNTGVAELIQMLHEPAGYTGRQVPIERVIHLDLDYIYDPNPVQQEINLSRVLDRIKRLHPTTVYLQAFADPDGDGVADEVYFPNRHLPMRADLFSRVAWQLSTRVGVKVYAWMPVMAFRLPESDPAASHIVQVMPDAPSTASQNRYHRLSIFDPLVRKTILEIYEDLGKSAIFDGVLFHDDATLSDYEDANPAALDYYREAWQLPDSIKEIRKSPELRLRWAANKTAYINAFTVTLADTLHRYQPNLHTARNLYAQPVLNPESEEWYAQSLPSFLATYDFVSLMAMPYMEGAADPERWLDQLLQKVHAVPGALDKTIFELQSRDWKTSQPIPSETLAAQMRWLHLNGVRNFGYYPDDFQANVPQEDIIKPVISVETNVPVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSE7</accession>
    <name>A0A2S9GSE7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4686</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000044">
        <property type="protein sequence ID" value="PRC90618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90618">
        <property type="protein sequence ID" value="PRC90618"/>
        <property type="gene ID" value="S2091_4686"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC90618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="119" mass="12540" checksum="F666F498321089BB" modified="2018-07-18" version="1">MGNGGTNTQYSYGSTSNQLTQVSGSQVNTIQSDANGSITNNVNNQFAYDARGRMVSAQTAIGAVQYQINALGQRVLKVTPNGTTVFNYDQGGKLIGESTGTKGADYIYLNDIPVAVAQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSG3</accession>
    <name>A0A2S9GSG3_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 20">Methionine synthase</fullName>
            <ecNumber evidence="6 20">2.1.1.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="19 20">5-methyltetrahydrofolate--homocysteine methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="30" type="ORF">S2091_4658</name>
    </gene>
    <organism evidence="30 31">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="30 31" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="30 31">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="18 20">Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 20">
            <text>(6S)-5-methyl-5,6,7,8-tetrahydrofolate + L-homocysteine = (6S)-5,6,7,8-tetrahydrofolate + L-methionine</text>
            <dbReference type="Rhea" id="RHEA:11172"/>
            <dbReference type="ChEBI" id="CHEBI:18608"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:58199"/>
            <dbReference type="EC" id="2.1.1.13"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 20 23">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3 20 22">
            <name>methylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:28115"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4 20">Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-methionine from L-homocysteine (MetH route): step 1/1.</text>
    </comment>
    <comment type="domain">
        <text evidence="20">Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the vitamin-B12 dependent methionine synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="30">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.13" evidence="6 20"/>
    <dbReference type="EMBL" id="PUGF01000041">
        <property type="protein sequence ID" value="PRC90650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90650">
        <property type="protein sequence ID" value="PRC90650"/>
        <property type="gene ID" value="S2091_4658"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00051">
        <property type="reaction ID" value="UER00081"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031419">
        <property type="term" value="F:cobalamin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008705">
        <property type="term" value="F:methionine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042558">
        <property type="term" value="P:pteridine-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02069">
        <property type="entry name" value="methionine_synthase_B12_BD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1240.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.196.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003759">
        <property type="entry name" value="Cbl-bd_cap"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006158">
        <property type="entry name" value="Cobalamin-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036724">
        <property type="entry name" value="Cobalamin-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011005">
        <property type="entry name" value="Dihydropteroate_synth-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003726">
        <property type="entry name" value="HCY_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036589">
        <property type="entry name" value="HCY_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033706">
        <property type="entry name" value="Met_synthase_B12-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011822">
        <property type="entry name" value="MetH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036594">
        <property type="entry name" value="Meth_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000489">
        <property type="entry name" value="Pterin-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004223">
        <property type="entry name" value="VitB12-dep_Met_synth_activ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037010">
        <property type="entry name" value="VitB12-dep_Met_synth_activ_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02310">
        <property type="entry name" value="B12-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02607">
        <property type="entry name" value="B12-binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02965">
        <property type="entry name" value="Met_synt_B12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00809">
        <property type="entry name" value="Pterin_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02574">
        <property type="entry name" value="S-methyl_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000381">
        <property type="entry name" value="MetH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01018">
        <property type="entry name" value="B12-binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47644">
        <property type="entry name" value="SSF47644"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51717">
        <property type="entry name" value="SSF51717"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52242">
        <property type="entry name" value="SSF52242"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56507">
        <property type="entry name" value="SSF56507"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82282">
        <property type="entry name" value="SSF82282"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02082">
        <property type="entry name" value="metH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50974">
        <property type="entry name" value="ADOMET_ACTIVATION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51332">
        <property type="entry name" value="B12_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51337">
        <property type="entry name" value="B12_BINDING_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50970">
        <property type="entry name" value="HCY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50972">
        <property type="entry name" value="PTERIN_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 20" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="10 20 22" id="KW-0846">Cobalamin</keyword>
    <keyword evidence="17 20 21" id="KW-0170">Cobalt</keyword>
    <keyword evidence="13 20 21" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16 20" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="8 20 24" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="31" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="14" id="KW-0677">Repeat</keyword>
    <keyword evidence="12 20 22" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="11 20 24" id="KW-0808">Transferase</keyword>
    <keyword evidence="15 20 21" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Hcy-binding" evidence="25">
        <location>
            <begin position="20"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="domain" description="Pterin-binding" evidence="26">
        <location>
            <begin position="376"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="domain" description="B12-binding N-terminal" evidence="29">
        <location>
            <begin position="667"/>
            <end position="761"/>
        </location>
    </feature>
    <feature type="domain" description="B12-binding" evidence="28">
        <location>
            <begin position="766"/>
            <end position="905"/>
        </location>
    </feature>
    <feature type="domain" description="AdoMet activation" evidence="27">
        <location>
            <begin position="920"/>
            <end position="1252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Methylcob(III)alamin binding" evidence="22">
        <location>
            <begin position="776"/>
            <end position="780"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="22">
        <location>
            <begin position="1219"/>
            <end position="1220"/>
        </location>
    </feature>
    <feature type="binding site" evidence="21 23">
        <location>
            <position position="265"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="21 23">
        <location>
            <position position="330"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="21 23">
        <location>
            <position position="331"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="22">
        <location>
            <position position="711"/>
        </location>
        <ligand>
            <name>methylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:28115"/>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="21">
        <location>
            <position position="779"/>
        </location>
        <ligand>
            <name>methylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:28115"/>
        </ligand>
        <ligandPart>
            <name>Co</name>
            <dbReference type="ChEBI" id="CHEBI:27638"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="22">
        <location>
            <position position="824"/>
        </location>
        <ligand>
            <name>methylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:28115"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="22">
        <location>
            <position position="828"/>
        </location>
        <ligand>
            <name>methylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:28115"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="22">
        <location>
            <position position="884"/>
        </location>
        <ligand>
            <name>methylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:28115"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="22">
        <location>
            <position position="971"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="22">
        <location>
            <position position="1165"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010398"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00013998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022628"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00025552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00031040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="PIRNR" id="PIRNR000381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="PIRSR" id="PIRSR000381-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="PIRSR" id="PIRSR000381-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="24">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="25">
        <source>
            <dbReference type="PROSITE" id="PS50970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="26">
        <source>
            <dbReference type="PROSITE" id="PS50972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="27">
        <source>
            <dbReference type="PROSITE" id="PS50974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="28">
        <source>
            <dbReference type="PROSITE" id="PS51332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="29">
        <source>
            <dbReference type="PROSITE" id="PS51337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="30">
        <source>
            <dbReference type="EMBL" id="PRC90650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="31">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="1252" mass="137440" checksum="35BC1D10523A38F4" modified="2018-07-18" version="1">MTIASATSPAIKPNDMCATEIQLREILARRILILDGAMGTMIQQYHLTEVDYRGDRFKDFTGPGRELFVKGNNELLTLTQPHIISEVHEKYLAAGADLIETNTFGATTVAQDDYHMAHLAYEMNVAAAKLARAACDKYSSPDKPRFVAGALGPTPKTASISPDVNDPAARNVTFDQLVTAYLDQTRGLVEGGSDVLLVETIFDTLNCKAALFAIETFFETSGKRLPVMISGTVTDASGRILSGQTVPAFWNSVRHIKPLTVGLNCALGATLMRPYAEELSNIADTFVCIYPNAGLPNPMSDTGFDETPDVTSSLVREFAESGFVNIAGGCCGTTPAHIQAIAEQIKNIAPRKIPEVPKVMRLSGLEPFVIDDQSLFVNVGERTNVTGSKAFARLILNEQYDEALAVARQQVENGAQIIDINMDEAMLDSVAAMTRFLNLIASEPDIARVPLMIDSSKWSVIEAGLKCVQGKAIVNSISMKEGETEFLRQATLCKRYGAAVIVMAFDEKGQADTFERKIEICQRAYSLLISQLDFAPEDIIFDPNIFAIATGIEEHNNYAVDFINATRWIKDNLPGAKISGGVSNVSFSFRGNDPAREAIHTVFLYHAIQAGLTMGIVNAGMVGVYSELSQALRECVEDVVLNRRPDATERMIDMASTLKAGDKKIEATLEWRSEPVAKRLSHAMVHGITQWIVEDTEEARQGFEFPIQVIEGPLMDGMNIVGDLFGQGKMFLPQVVKSARVMKQAVAHLLPFIEAEKKRTGDNKPKGKIVIATVKGDVHDIGKNIVSVVLQCNNFEVVNMGVMVPCSEILAVAKAENADIIGLSGLITPSLEEMAHVAKEMQRDPHFRMLKIPLLIGGATTSRAHTAVKIAPNYEGPVVYVPDASRSVSVAQSLLTVDQREQYVEDLAVDYERIRVLHANKKALPTVSLAVARKNKMVVPFDGVNAPVKPKFIGRRILKNVDLATVAHYIDWGPFFQTWDLAGPYPAILTDEVVGEAATKVFEEGQAMLKKIIEGRWLTANGVIMLLPANSVNDDDIEIYTDETRSQVALTYYGVRQQAEKPVIDGVQRPNQCLSDFIAPKASGVQDYIGMFAVTAGLGIEKHEQRFEKANDDYSSIMLKSLADRLAEALAEYLHERVRKDFWGYAAEEQLSNADLIKEGYSGIRPAPGYPACPEHTVKADVFKLMQCEEIDMHITESYAMIPGAAVSGFYFGHPQSKYFNVGKINQDQVVDMAARRGIAQEEIERWLAPNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSJ6</accession>
    <name>A0A2S9GSJ6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Acyl-CoA dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_4625</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000039">
        <property type="protein sequence ID" value="PRC90675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90675">
        <property type="protein sequence ID" value="PRC90675"/>
        <property type="gene ID" value="S2091_4625"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003995">
        <property type="term" value="F:acyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006089">
        <property type="entry name" value="Acyl-CoA_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="SSF47203"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="SSF56645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00072">
        <property type="entry name" value="ACYL_COA_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA_dh_N" evidence="7">
        <location>
            <begin position="9"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_M" evidence="6">
        <location>
            <begin position="123"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_1" evidence="5">
        <location>
            <begin position="232"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC90675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="380" mass="42164" checksum="9BE2C0CC80C1231A" modified="2018-07-18" version="1">MNTVSTWMTPELESFRDAVRRFVNLEIVPHQEKWKKQQHVDRSVWNKAGEMGMLLADISDEYGGSGGTFAHQCVVFEELATAGDSCFGIHVHAIVAHYLNNQGTEAQKKKYLPQLASGEMVAAIAMSEPSAGSDLKGIRSTAIKKGDDYVLNGSKTFISNGYLADLILVVCKTDPDAGSKGVSLLLLETKDCPGFKVGRILEKIGQKGQDTCELFFDNVRVPQENILGGVEGKGFAQLMTELPYERTILGVGGVAVIERALRLTIEYTRERKAFGQPLIEMQNTRFVLAEIKTEATIARTFIDRCIVDMIEGRMDAELASMAKYWISDLQCKVIDQCLQLFGGYGYMLEYPIAQMYVDARVQKIYGGANEIMKEIIARSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSK4</accession>
    <name>A0A2S9GSK4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4626</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000039">
        <property type="protein sequence ID" value="PRC90676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90676">
        <property type="protein sequence ID" value="PRC90676"/>
        <property type="gene ID" value="S2091_4626"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="87"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="115"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="142" mass="15147" checksum="FE9214CF3522D3C0" modified="2018-07-18" version="1">MNKVLLIAASLSAIAALLHIAIIINGANWYRFFGAGERMARAAERGDWYPALVTTGIALVLASWAGIALAGAGAVSLPSGLLPYLKAALVLITLIYLIRGLVVVPLYFMAQATPFVVWSSVICLVFAVFHIVGVIQVWPNLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSL1</accession>
    <name>A0A2S9GSL1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Conserved repeat domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_4602</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000038">
        <property type="protein sequence ID" value="PRC90709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90709">
        <property type="protein sequence ID" value="PRC90709"/>
        <property type="gene ID" value="S2091_4602"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00161">
        <property type="entry name" value="RICIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001434">
        <property type="entry name" value="DUF11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021862">
        <property type="entry name" value="DUF3472"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035992">
        <property type="entry name" value="Ricin_B-like_lectins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000772">
        <property type="entry name" value="Ricin_B_lectin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11958">
        <property type="entry name" value="DUF3472"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00652">
        <property type="entry name" value="Ricin_B_lectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50370">
        <property type="entry name" value="SSF50370"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01451">
        <property type="entry name" value="B_ant_repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50231">
        <property type="entry name" value="RICIN_B_LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ricin B-type lectin" evidence="2">
        <location>
            <begin position="488"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC90709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="647" mass="65264" checksum="9A026E0B2E7D45DD" modified="2018-07-18" version="1">MRSANYEKIITMILPKTTYKKTLRLSWSKKFITNVKLGLLIAGLGSLLMACGGGSGTASGASSSGAAGSTGGTGSTGGTVLAPVPAPAPTPTPTPTPPVAPTTPAVTSTYSAAWSLANSTAAVGSSTTATIVLSNTGTTAASNAQFTLHLPTGFTAANLVQGCGGTLSSAANSAAVTMTGAVVPAGGTCSFGFTLTIPTLALASNYSPVFSITAASGSSNASLAGQTLPTLTLTSNTPTATPTADGKTPGAYSWWYVPSTTTTMSEMDFFITPKVDPGPDSNVFWSNQSYALNGYTGMQSTMLVNGTGSGRQFLFSLWNAVAATPGSTGSTCTVSTTADDGSAGAQCKILYNWQVNHTYQFSVIAQGNSWFKSTVTDVTPGIANPVSFVIGSIQQSATLYPHMTSSIPTIPGSSDFVQWIEYFDWNNHRTTCMSVPSTDAVMSASVVDATTGKTIAFAPSSTDTGASGSCTNINDAISANSSEIKGGTGQTVQGLFKAGNTGVCLSSVSGVSDGTPAGSNSAILSACPTAASVSANGGSSAASSLWVYAADHSIQLHDNYCLTVSDGIGASGANVAIESCVPGAINQQWTITTDTSTTQQSIASVLSGFCLNPANTTTTSKQNIILDLAACSAATDTWTIPGSSFSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSQ6</accession>
    <name>A0A2S9GSQ6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4567</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000037">
        <property type="protein sequence ID" value="PRC90741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90741">
        <property type="protein sequence ID" value="PRC90741"/>
        <property type="gene ID" value="S2091_4567"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="185"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="290"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="314" mass="31353" checksum="BAE1CB9F34AA9F14" modified="2018-07-18" version="1">MMNINALQSPSSSYTPVTGSSSANSQRNSSPNNSDAAAASTVVLQSTQVTLSSSANLNFYNIPSSLGLELTPQNNAWSVPLQQTGSATSSGASLLGEFAENELASKLSSPSELAGATVTINSFNSQSTNTVGAAQEVSSGQGVDQSATVLEASNSITLQGSGEITLADGEVIPFTAELSTSASIVESSATQTSDGATTSSAPSTSSTSPAPSATSSSSPLNLSSSNQSPNLPDSTTAQPASNKTGAGAASEWSNMLQQYNFLLNLFDAVKAAVENLQVPQSQLLAVGAANNSSPVSTPASTTNTAASTGAIASH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSS1</accession>
    <name>A0A2S9GSS1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">3-methyladenine DNA glycosylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4508</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000036">
        <property type="protein sequence ID" value="PRC90760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90760">
        <property type="protein sequence ID" value="PRC90760"/>
        <property type="gene ID" value="S2091_4508"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008725">
        <property type="term" value="F:DNA-3-methyladenine glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005019">
        <property type="entry name" value="Adenine_glyco"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011257">
        <property type="entry name" value="DNA_glycosylase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03352">
        <property type="entry name" value="Adenine_glyco"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48150">
        <property type="entry name" value="SSF48150"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC90760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="192" mass="21774" checksum="12FD787DE8A72767" modified="2018-07-18" version="1">MTIKRCGWANPANPLYLAYHDHDWGVPCHDETTLFEMLNLEGAQAGLSWETILNKRENYRQAFDGWNAEKIAHYDATKVAELLANPGIVRNRLKVAATINNAQAYLRLRDEVGGLDPYLWGFVNGKTLVNHIDDYKQAPPKTELSERISKDLAKRGFKFIGPTIIYAYMQSIGMVDDHILSCFKRSGKSKKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GT48</accession>
    <name>A0A2S9GT48_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Helix-turn-helix domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_4383</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000033">
        <property type="protein sequence ID" value="PRC90890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90890">
        <property type="protein sequence ID" value="PRC90890"/>
        <property type="gene ID" value="S2091_4383"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="2">
        <location>
            <begin position="16"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC90890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="108" mass="12147" checksum="4C777DBFAEFC2268" modified="2018-07-18" version="1">MSNPTHPKNTIISRRLRQARQSRDLSQDRLGVMAGLEESSSSARMSRYESGIHEPTYQFVEAIAKVLGISPAFFYCADDRLAEIILIYSGLSETKRKALLQQATKITE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTD3</accession>
    <name>A0A2S9GTD3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4275</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000031">
        <property type="protein sequence ID" value="PRC90979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90979">
        <property type="protein sequence ID" value="PRC90979"/>
        <property type="gene ID" value="S2091_4275"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC90979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="101" mass="10899" checksum="E400778AD6667848" modified="2018-07-18" version="1">MEIKTVISCPLGSKCEEIRGDALHRCAWFIQLAGTNPNTGDAVDERGCAMSWVPILLIENSQQQRSTNAAVESFRNEVVNASNASQHLFAVAAGIPTLINT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTE1</accession>
    <name>A0A2S9GTE1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phage protein U</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4280</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000031">
        <property type="protein sequence ID" value="PRC90984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90984">
        <property type="protein sequence ID" value="PRC90984"/>
        <property type="gene ID" value="S2091_4280"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009734">
        <property type="entry name" value="Myoviridae_GpU"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06995">
        <property type="entry name" value="Phage_P2_GpU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC90984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="169" mass="17951" checksum="AE7C2D7D20AB2C3B" modified="2018-07-18" version="1">MMALGMFVFSLPTLAYQELQRQTEWKHPGTSRVGTRDAHQFTGKGDDTITLSGWIAPELTGSLYSLDALRMMADTGQSWILIQGNGRILGTFIITGLTENSSHLAATGAAGKVDFTISLKCIDDDLPGLMNSLGDPGSIKNMLGLDGLARGANDALTAGNRFGSAMVRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTE8</accession>
    <name>A0A2S9GTE8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4264</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000031">
        <property type="protein sequence ID" value="PRC90968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90968">
        <property type="protein sequence ID" value="PRC90968"/>
        <property type="gene ID" value="S2091_4264"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC90968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="187" mass="21468" checksum="5AC7A01F2D950EC6" modified="2018-07-18" version="1">MSSLSIFLRQVRSRSREHLQAMQLLAQARLAGQMVSVLRQELDSMVRVIYLLTRNLERRELLIEASVKGEKWLQENSRATVTDREMVDLSQSLQGWTQSVYKFGCAFIHLSGLHDYNDRDPLVQLPRQERHDILAHCRHYHGGSLTDDASFEDLVPFFPRVLEKIANNLESYLVALENGEVCSAAEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTN8</accession>
    <name>A0A2S9GTN8_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">Transaldolase</fullName>
            <ecNumber evidence="6 7">2.2.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">tal</name>
        <name evidence="9" type="ORF">S2091_4244</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 7">Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = beta-D-fructose 6-phosphate + D-erythrose 4-phosphate</text>
            <dbReference type="Rhea" id="RHEA:17053"/>
            <dbReference type="ChEBI" id="CHEBI:16897"/>
            <dbReference type="ChEBI" id="CHEBI:57483"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="2.2.1.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4 7">Carbohydrate degradation; pentose phosphate pathway; D-glyceraldehyde 3-phosphate and beta-D-fructose 6-phosphate from D-ribose 5-phosphate and D-xylulose 5-phosphate (non-oxidative stage): step 2/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 7">Belongs to the transaldolase family. Type 2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.2.1.2" evidence="6 7"/>
    <dbReference type="EMBL" id="PUGF01000030">
        <property type="protein sequence ID" value="PRC91056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91056">
        <property type="protein sequence ID" value="PRC91056"/>
        <property type="gene ID" value="S2091_4244"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00115">
        <property type="reaction ID" value="UER00414"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004801">
        <property type="term" value="F:transaldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006098">
        <property type="term" value="P:pentose-phosphate shunt"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00955">
        <property type="entry name" value="Transaldolase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00493">
        <property type="entry name" value="Transaldolase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001585">
        <property type="entry name" value="TAL/FSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004732">
        <property type="entry name" value="Transaldolase_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10683">
        <property type="entry name" value="PTHR10683"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00923">
        <property type="entry name" value="TAL_FSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036915">
        <property type="entry name" value="Trnald_Bac_Plnt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00876">
        <property type="entry name" value="tal_mycobact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0570">Pentose shunt</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0704">Schiff base</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="360"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with substrate" evidence="7">
        <location>
            <position position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003518"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00008426"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00013151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC91056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="393" mass="43300" checksum="8A5699E3F0703559" modified="2018-07-18" version="1">MNTTQQLHDLGQSVWLDNITRELLQNGTLQNYIDNYNVTGLTSNPTIYEQAIRHSHFYDEEIKEKATEGKTNSEIFFELAIEDLRQAADLFAPIHKATSGVDGWVSLEISPLLANDVNATISEAIRLHESAQRENLFIKIPGTPSGCIAIEEVIFAGVPVNVTLLFSCEQYMKAGSAYMRAIERRIAAGLNPKVASVASLFVSRWDVAVKDKVPADLHNKLGIAIAQRTYRAYQHLLDSPRWLDLAKAGAQTQRLLWASTGSKDSAISDTFYVQELASPNTINTLPEKTLLTFGDHGLIGHTMSVDGDNAEQEIALFMKAGIDIDLLAGQLQTEGTASFTKSWNELLAMINSKSVTLANGEAEKQQPTPTIPTEPTAPSRPTLRLKKYSKELT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTS2</accession>
    <name>A0A2S9GTS2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ABC-type dipeptide/oligopeptide/nickel transport system permease component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_4172</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000029">
        <property type="protein sequence ID" value="PRC91076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91076">
        <property type="protein sequence ID" value="PRC91076"/>
        <property type="gene ID" value="S2091_4172"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045621">
        <property type="entry name" value="BPD_transp_1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19300">
        <property type="entry name" value="BPD_transp_1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="101"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="132"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="175"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="241"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="279"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="95"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC91076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="312" mass="34745" checksum="92F95067B7290904" modified="2018-07-18" version="1">MSAYILRRLWQMLPTLLGVILLVFFLFNWVGGDPAYLLAGKMSNPVQIAEIRAQLGIDKPYYVQLGIFIQQIATFNFGVSWSTGETVSSIISTRMGPSLTVLIPLTILETAIAIALALSIAFIRGSLTDRMVMIACTVGMSVSILVYIIVGQYVFAYQLGLFPVQGWGNNFFENLFRYSALPILIALAVSVAPDLRLFRSFVLDEVNQDYVRTARAKGLSERRIVWVHVLRNASIPIITHVMANLPALLIGAFLIERFFGIPGIGREIILAVERSDFPVIKAITIYVAIVTMIFNLLTDLLYQAVDPRIKLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTS5</accession>
    <name>A0A2S9GTS5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="10">AlkA N-terminal domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">S2091_4211</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000029">
        <property type="protein sequence ID" value="PRC91115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91115">
        <property type="protein sequence ID" value="PRC91115"/>
        <property type="gene ID" value="S2091_4211"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00056">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1670.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035451">
        <property type="entry name" value="Ada-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004026">
        <property type="entry name" value="Ada_DNA_repair_Zn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010316">
        <property type="entry name" value="AlkA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037046">
        <property type="entry name" value="AlkA_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011257">
        <property type="entry name" value="DNA_glycosylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003265">
        <property type="entry name" value="HhH-GPD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023170">
        <property type="entry name" value="HhH_base_excis_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018062">
        <property type="entry name" value="HTH_AraC-typ_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02805">
        <property type="entry name" value="Ada_Zn_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06029">
        <property type="entry name" value="AlkA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00730">
        <property type="entry name" value="HhH-GPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01009">
        <property type="entry name" value="AlkA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00478">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48150">
        <property type="entry name" value="SSF48150"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57884">
        <property type="entry name" value="SSF57884"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00041">
        <property type="entry name" value="HTH_ARAC_FAMILY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0227">DNA damage</keyword>
    <keyword evidence="8" id="KW-0234">DNA repair</keyword>
    <keyword evidence="7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="9">
        <location>
            <begin position="100"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC91115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="513" mass="56103" checksum="254FD5BFF2924984" modified="2018-07-18" version="1">MKNLFTPSTPITASSLDHANCYRALCAKDSRFDGEFFVGVSTTGIYCRPVCRVKTPRPSSCTFYQNASSAEAAGFRPCLRCRPELAPYALQQNLAYAIWQRISAGALNNRGDGGNMQELAQQVGLSARQLQRLMQNHFGVSPIELAQTARLLFAKKLLQETSLAMTELAYAAGFGSVRRFNALFLNRYGMAPSAIRRSATSKASTDHITLRLAYRAPFAWDTMLDYLAGRIISGVEAIEEDVGVNKQQRYYVRSVNFWHGKEQLQGWLKVSNLSKEQQLEVQLSSNFSPVLMPLLAKVRQQFDLDANPTIVEAHLSSDPLLAAQIKRTPGLRVPGAFNRFELAIRAVLGQQISVAGATTLAARLIQQFGTPSTTPFSSITHHFPEPAALAALSQEQIAQLGMPKSRAATILAVAQFAADGGLELPLGSSLDKAVAHLKTVRGIGEWTAQYIALRVLRYPDAFPAGDLGLQKAAAVDTENSAGKISEAQLLNRAQSWTPWRGYAALLLWQSLSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTX4</accession>
    <name>A0A2S9GTX4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SMI1 / KNR4 family (SUKH-1)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4164</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000028">
        <property type="protein sequence ID" value="PRC91163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91163">
        <property type="protein sequence ID" value="PRC91163"/>
        <property type="gene ID" value="S2091_4164"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018958">
        <property type="entry name" value="Knr4/Smi1-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037883">
        <property type="entry name" value="Knr4/Smi1-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09346">
        <property type="entry name" value="SMI1_KNR4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160631">
        <property type="entry name" value="SSF160631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SMI1_KNR4" evidence="1">
        <location>
            <begin position="21"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="165" mass="18655" checksum="830551590A612A32" modified="2018-07-18" version="1">MHQVYSRFMGLFDRSHSMVCATDAEITEMENELDTMVPESYRAFVIQFGEAFTPSLLSLVTDNNIDLFDIQNIVLPRKAVVGTKAYWEAGMPTQNVGFANDCMGNMFCFHRIPRSSPRPLDAPVYLFDHDFGTVELVAPSMEKWLQTYVSASMTTCTRHVPAGRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTY3</accession>
    <name>A0A2S9GTY3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Bacterial SH3 domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4169</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000028">
        <property type="protein sequence ID" value="PRC91168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91168">
        <property type="protein sequence ID" value="PRC91168"/>
        <property type="gene ID" value="S2091_4169"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="463" mass="50851" checksum="CBA49E27E31D74DF" modified="2018-07-18" version="1">MQYATVTIGLGIAVGLSILPPSSLASEMQPGPMWVVGSYVNIRQAADDKAKVIEHLTANTPIHLVGEKGRYCEISWAQSRSGFVACQFLGAKPLQLSDVERSPANDNDEHFEASPLRAFWIEPSFSRLRAAGAYFEKKMLTEAAAKKEADQLKAWLEVPAVSPNVAKSITISRFSVPEFDAMKALAKAGMQPPPLLNSIYPDVASLQAKPDSATMPAEHLPLLAFLPALGASRFSAQAQVGAMQTTTDQLSALFQIPYQVEPLNKPYTVSPQYEDPYIFGSWDIGDVNLSLVRPVHDVGIYTNGHVKDLETSLNQWDGFYIDYEATQECGSFVIDAHLHDHASGDYIVSKLPIDGLLMFFRSPVAVNTSTARVEMQRHELSAFQKKARRELQKNMIHQVVQYTVTLAGDFAPDFTVFELRGYSDVPGAESGTTGPYEAIMRYYFVNIGGSWKLLDVDGLSGCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTZ8</accession>
    <name>A0A2S9GTZ8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4097</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000027">
        <property type="protein sequence ID" value="PRC91202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91202">
        <property type="protein sequence ID" value="PRC91202"/>
        <property type="gene ID" value="S2091_4097"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008523">
        <property type="entry name" value="DUF805"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34980">
        <property type="entry name" value="PTHR34980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05656">
        <property type="entry name" value="DUF805"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="26"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="77"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="111" mass="12694" checksum="6D546F0860F18704" modified="2018-07-18" version="1">MTFAESIRICFNKYADFNGRASRSEFWWFALFTFLVSAALNIINRSGTLSGLFSLATLIPSLAVGARRLHDTNRSGWLQLLWFIPIIGWIFLLIWDVQDSDKEANRFDTAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GU58</accession>
    <name>A0A2S9GU58_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Cysteine desulfurase IscS</fullName>
            <ecNumber evidence="10">2.8.1.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">iscS</name>
        <name evidence="14" type="ORF">S2091_4028</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>[sulfur carrier]-H + L-cysteine = [sulfur carrier]-SH + L-alanine</text>
            <dbReference type="Rhea" id="RHEA:43892"/>
            <dbReference type="Rhea" id="RHEA-COMP:14737"/>
            <dbReference type="Rhea" id="RHEA-COMP:14739"/>
            <dbReference type="ChEBI" id="CHEBI:29917"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="ChEBI" id="CHEBI:64428"/>
            <dbReference type="EC" id="2.8.1.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 10 11">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="10">Cofactor biosynthesis; iron-sulfur cluster biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.7" evidence="10"/>
    <dbReference type="EMBL" id="PUGF01000026">
        <property type="protein sequence ID" value="PRC91243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91243">
        <property type="protein sequence ID" value="PRC91243"/>
        <property type="gene ID" value="S2091_4028"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00266"/>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031071">
        <property type="term" value="F:cysteine desulfurase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044571">
        <property type="term" value="P:[2Fe-2S] cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00331">
        <property type="entry name" value="Cys_desulf_IscS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020578">
        <property type="entry name" value="Aminotrans_V_PyrdxlP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010240">
        <property type="entry name" value="Cys_deSase_IscS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016454">
        <property type="entry name" value="Cysteine_dSase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11601:SF34">
        <property type="entry name" value="PTHR11601:SF34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005572">
        <property type="entry name" value="NifS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02006">
        <property type="entry name" value="IscS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00595">
        <property type="entry name" value="AA_TRANSFER_CLASS_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="4" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 10" id="KW-0408">Iron</keyword>
    <keyword evidence="9 10" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="6 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 10" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_5" evidence="13">
        <location>
            <begin position="20"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="region of interest" description="Pyridoxal phosphate binding" evidence="10">
        <location>
            <begin position="216"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="269"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="active site" description="Cysteine persulfide intermediate" evidence="10">
        <location>
            <position position="341"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="168"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="196"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="256"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" description="via persulfide group" evidence="10">
        <location>
            <position position="341"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
            <note>ligand shared with IscU</note>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="10">
        <location>
            <position position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="PRC91243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="417" mass="46520" checksum="3093D715D16FDADC" modified="2018-07-18" version="1">MNNPIKNSLLETTTAPHFPIYMDYSATTPIDPRVADKMIPYLREQFGNPASRSHVYGWTAEQAVEEARANVAALIGADPREIVWTSGTTESNNLALKGAAQFYKTRGKHIITVKTEHKAVLDTVRELERQGFEATYLQPQENGLITVEQLAAAVRPDTILVSVMWVNNEIGVIQPIAEIGEFCRSKNIIFHCDAAQATGRVDIDMETVKVDLLSLTAHKTYGPKGIGALYVRRKPRIRIEAQMHGGGHERGMRSGTLPTHQIVGMGEAFRLAKEEMVEENRRIEALRDRLANGLKEIEEVYINGDMAHRIPHNLNVSFNYVEGESLIMAIKDIAVSSGSACTSASLEPSYVLRALGRSDELAHSSIRFTMGRFTTEQEIDFTIALMKEKVSKLRDLSPLWDMYKEGIDISSIQWAAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUA3</accession>
    <name>A0A2S9GUA3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_3952</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000025">
        <property type="protein sequence ID" value="PRC91281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91281">
        <property type="protein sequence ID" value="PRC91281"/>
        <property type="gene ID" value="S2091_3952"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004638">
        <property type="entry name" value="EmrB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00711">
        <property type="entry name" value="efflux_EmrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="28"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="71"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="97"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="124"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="158"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="185"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="250"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="292"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="319"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="351"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="381"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="497"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="7">
        <location>
            <begin position="33"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC91281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="532" mass="57058" checksum="62D2629E1E53C5CF" modified="2018-07-18" version="1">MSKTVNGNAAGSKPAPPRHIEHPPLTGATLLWGTLALALATFMIVLDSSIANVSIPAISGDLGVSPTQGTWVITSFAVANAISIPLTGWLTQRFGQVRLFVISILLFVLASWLCGFAPNIESLIAFRVLQGAVSGPIIPLSQALLLSSYPKAKAGMALALWAMTTLVAPVMGPLLGGWITDHISWSWIFYINIPVGFIASSITWSLYKERDSIIHKLPIDKVGLFLLIVWVGAMQIMMDKGKELDWFASNQIIALAVTAVVGFAFFIAWELTDDHPVVDLTLFARRNFWTGTIALSLAYGVFFGNVVLLPLWLQQYMGYTATQAGIVLAPVGVMAILLSPMVGKSIGKVDPRILATISFLVFALVLWMRSRFNTNADLTTILIPTVVQGVAMAFFFIPLVSLTLSGLTPDKIPAASGLSNFARITAGAFGTSIATTLWENRAAMHHAHLTEKLNLASIPMTQTVSGLQASGFSSEQAMAVINRSIDQQAYMMSANDIFFASSMIFFVLIGVVWLARPVKSSGGSAADASGAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUD9</accession>
    <name>A0A2S9GUD9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000025">
        <property type="protein sequence ID" value="PRC91329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91329">
        <property type="protein sequence ID" value="PRC91329"/>
        <property type="gene ID" value="S2091_4000"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.33.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035940">
        <property type="entry name" value="CAP_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015779943" evidence="1">
        <location>
            <begin position="18"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="367" mass="38847" checksum="00F7F2D9FE3BE927" modified="2018-07-18" version="1">MKKLALIGMLVTAFTLASCGGSNSPPTNLVIPGSPQNYLSTPTYVQGTDEYNAFMAINAFRFSVGLGYWQQNVYLDQAAQKHMAYSTANSAIISNPYQQDIEIVGNPSYFATTPSARAIALGYYVMQNTTAAPNGTPFAAVGELYALGPASSPTSTAILNSMVNTIYHRSGLMAQSTREIGLARDTSGPATALTHWWISHGRLDGGQSVASNYFAVYPNNQLTNVPLSMTMESPSVYPAYTTPAQFNANTSSPISVTTAIITNLNNAAFTVTVAGSSTPLAGKTWTMANDPNLNTSSYSAATAALTTPPAPVPTIAANEAFWVGNAPFLPNTTYNVTFTGSTYLMPYAITNNVSQTWQFTTGTSTGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUL5</accession>
    <name>A0A2S9GUL5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative esterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3891</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000024">
        <property type="protein sequence ID" value="PRC91346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91346">
        <property type="protein sequence ID" value="PRC91346"/>
        <property type="gene ID" value="S2091_3891"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008886">
        <property type="entry name" value="UPF0227/Esterase_YqiA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35602">
        <property type="entry name" value="PTHR35602"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05728">
        <property type="entry name" value="UPF0227"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="194" mass="21523" checksum="35131157112A00D4" modified="2018-07-18" version="1">MILYLHGFRSSPASFKAQMIRATLQETGRAEEYLCPQLPASPQSAIALCLQLCEQIDPSELTIIGSSLGGYYATYLAEKLSCRAVLLNPAVKPPRDLAAYIGVTTMYHSDDVFEFTQEYAQELSQFSINQITQPERYFLLAATGDEVLDWCEMVAHYLGAKQHIITGSDHGISEFADYLDQVMEFCDGAMDGAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUQ2</accession>
    <name>A0A2S9GUQ2_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">3-hydroxyacyl-CoA dehydrogenase</fullName>
            <ecNumber evidence="2">1.1.1.35</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">S2091_3877</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>a (3S)-3-hydroxyacyl-CoA + NAD(+) = a 3-oxoacyl-CoA + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:22432"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57318"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:90726"/>
            <dbReference type="EC" id="1.1.1.35"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Lipid metabolism; fatty acid beta-oxidation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.35" evidence="2"/>
    <dbReference type="EMBL" id="PUGF01000023">
        <property type="protein sequence ID" value="PRC91462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91462">
        <property type="protein sequence ID" value="PRC91462"/>
        <property type="gene ID" value="S2091_3877"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00659"/>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003857">
        <property type="term" value="F:3-hydroxyacyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070403">
        <property type="term" value="F:NAD+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006635">
        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006176">
        <property type="entry name" value="3-OHacyl-CoA_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006108">
        <property type="entry name" value="3HC_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00725">
        <property type="entry name" value="3HCDH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02737">
        <property type="entry name" value="3HCDH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="4" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="5" id="KW-0520">NAD</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="3HCDH_N" evidence="9">
        <location>
            <begin position="293"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="domain" description="3HCDH" evidence="8">
        <location>
            <begin position="473"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="domain" description="3HCDH" evidence="8">
        <location>
            <begin position="601"/>
            <end position="685"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC91462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="691" mass="74215" checksum="7318D4F5951ED76A" modified="2018-07-18" version="1">MTAEYQAHGAVAVITLTNPPVNGMNFQTRTAAVECINRALDDASIKAIVITGAGNAFSGGADIKEFNSPKALAEPSLHTLIDVVENSSKPVVAAIHHVCMGGGLELSLGCHYRVATPGTQIALPEVKLGLLPGAGGTQRLPRVVGLELALKMITSGAPELSEKLANTALFDEILTGDCVAGAIAFAEKIADLRPLPKVRNLNVTHPQLQEVLNAARAQAQRGFLKAPLHCVEAIAAAANLPFDEGIQFERQTFYKLVVSPESTALRHAFFAERAASKIPDVPADTPIRSIKSAAVVGAGTMGGGIAMNFANAGIPVVILETKPEALEKGLAIIAKNYQNTRDKGKLSPEKCAERIALISGTLDYNAIGQADIVVEAVFEEMNVKKSVFEKLDEVMRQGAILASNTSTLDLNKIASFTKRPQDVVGMHFFSPANVMKLLEIVRGKETSNEVLASAMALSKKLKKVGVVSGVCDGFIGNRMLEQYIRQAGFLLDEGCLPAQVDSAMEKMGFAMGPFRMSDLAGNDISYAIRKRRAIEKPDMLYSKTADQLCELGRFGQKTGAGWYDYQAGDRTAHPSDLVNQLINDHSKQIGIERRAITDQEITERLIYALVNEAAYILEEGIAHRASDIDMVYLSGYGFPLHLGGPMLYADTVGLAKVVAAIQHYAQGHCGKVWKVAPLLQELAAKEQKFNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUU1</accession>
    <name>A0A2S9GUU1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">N-acetylneuraminate synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3758</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000022">
        <property type="protein sequence ID" value="PRC91480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91480">
        <property type="protein sequence ID" value="PRC91480"/>
        <property type="gene ID" value="S2091_3758"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016051">
        <property type="term" value="P:carbohydrate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006190">
        <property type="entry name" value="AFP_Neu5c_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036732">
        <property type="entry name" value="AFP_Neu5c_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020007">
        <property type="entry name" value="N-AcNeuraminate_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013132">
        <property type="entry name" value="Neu5Ac_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013974">
        <property type="entry name" value="SAF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03102">
        <property type="entry name" value="NeuB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08666">
        <property type="entry name" value="SAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51269">
        <property type="entry name" value="SSF51269"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03569">
        <property type="entry name" value="NeuB_NnaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50844">
        <property type="entry name" value="AFP_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AFP-like" evidence="1">
        <location>
            <begin position="286"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="336" mass="36588" checksum="2B71BF6A019E3BDA" modified="2018-07-18" version="1">MTKLMTKVFIIAEAGVNHNGSLELAKKLIDVAAHAGADAVKFQTFKADKLVCRSAKKAEYQLQSSAADESQFDMLKKLELDEAAHHEIIRYCAEKNIQFLSTPFDHDSIDLLASLGMSTFKIPSGEITNLPYLRKVGKIAKDVILSTGMANLGEVEAALMHLCAAGLRKEKITVLHATTEYPCPINEVNLRAMQTMGAAFNVKVGYSDHTPGIEVAIAAVAMGASVIEKHFTLDRTMEGPDHKASLEPQELNAMVRGIRNVSLALGDGIKQASYSEAKNIPISRKSIVTASQIKIGDVFSANNLTVKRPGNGIDPMRWDEIIGQIAQRNYAPDEQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUV2</accession>
    <name>A0A2S9GUV2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">WbqC-like protein family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3756</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000022">
        <property type="protein sequence ID" value="PRC91478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91478">
        <property type="protein sequence ID" value="PRC91478"/>
        <property type="gene ID" value="S2091_3756"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014985">
        <property type="entry name" value="WbqC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08889">
        <property type="entry name" value="WbqC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="234" mass="26308" checksum="9EA0C93EECF43C4F" modified="2018-07-18" version="1">MICSIHQPCYFPWLGLLSKIAGSDTLILLDEVQLSDSAFQHRNQFLTLDGKVKYLTIPFVKQNYLNLPLKDIKIADPGWGVIHNNFLTNNYKKHPFFDQIYPEIAPLFSTPTTYLIEVILKSMDISMALLGIKTKIIMQHQLQYQHEAKKADLILQLLQATQATSYLSGTGAKIYQDDALFDSAGISISYNEFSHPIYPQKNTQQFISGLSCLDLLFNVGSVAASTMLARESSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUZ7</accession>
    <name>A0A2S9GUZ7_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Threonine-phosphate decarboxylase</fullName>
            <ecNumber evidence="5">4.1.1.81</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">L-threonine-O-3-phosphate decarboxylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">S2091_3809</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H(+) + O-phospho-L-threonine = (R)-1-aminopropan-2-yl phosphate + CO2</text>
            <dbReference type="Rhea" id="RHEA:11492"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:58563"/>
            <dbReference type="ChEBI" id="CHEBI:58675"/>
            <dbReference type="EC" id="4.1.1.81"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Cofactor biosynthesis; adenosylcobalamin biosynthesis.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.81" evidence="5"/>
    <dbReference type="EMBL" id="PUGF01000022">
        <property type="protein sequence ID" value="PRC91531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91531">
        <property type="protein sequence ID" value="PRC91531"/>
        <property type="gene ID" value="S2091_3809"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00148"/>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048472">
        <property type="term" value="F:threonine-phosphate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901605">
        <property type="term" value="P:alpha-amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009236">
        <property type="term" value="P:cobalamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005860">
        <property type="entry name" value="CobD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004838">
        <property type="entry name" value="NHTrfase_class1_PyrdxlP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01140">
        <property type="entry name" value="L_thr_O3P_dcar"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00105">
        <property type="entry name" value="AA_TRANSFER_CLASS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0169">Cobalamin biosynthesis</keyword>
    <keyword evidence="8" id="KW-0456">Lyase</keyword>
    <keyword evidence="7" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="10">
        <location>
            <begin position="51"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00003444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00029996"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC91531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="329" mass="35904" checksum="A558DA1350668A87" modified="2018-07-18" version="1">MLEHGGNLNDVIQRFGRARADWLDLSTGLNPHCYPAPELSADVWHRLPETSQELCAAASHYYGAPQMLAVAGTQAAIQALPRLRPPSKVVVAAPSYAEHAHHWGQYGHTLRQVPYTELAGVVCDCDVMVVCNPNNPTGALIEPELLLNWAEQLAARGGWLIVDEAFADTVPQNSVVAWSGQEGLIVLRSVGKFFGLAGLRLGFVAASLPLLRQMEELLGPWAISSAAQQIGCAALRDSAWQGATRLSLTASGKRLNALLLQCGIQANGSALFQWWPEPYAEQFWLHMAERGILVRLFSQAGRGIRLGLPPDEVGWRRLAGALEEWVIRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GV60</accession>
    <name>A0A2S9GV60_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3731</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000021">
        <property type="protein sequence ID" value="PRC91615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91615">
        <property type="protein sequence ID" value="PRC91615"/>
        <property type="gene ID" value="S2091_3731"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015692822" evidence="1">
        <location>
            <begin position="23"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="123" mass="12074" checksum="E247773ED2B1427B" modified="2018-07-18" version="1">MKSFVKTITLAASFLICASSFAQTPASAVNAATVKASAAASSAATSAGSTATNAASSATTATKAKVAAAGGAADKVWLNTKSNVYHCFGTKSYGTTKVGEYMSEADAKAKGGHADHGKACKAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVP5</accession>
    <name>A0A2S9GVP5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3481</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000019">
        <property type="protein sequence ID" value="PRC91726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91726">
        <property type="protein sequence ID" value="PRC91726"/>
        <property type="gene ID" value="S2091_3481"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="36"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="60"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="91" mass="10190" checksum="6EC99CAC2DB57260" modified="2018-07-18" version="1">MKELVCDVVIGFSGLLIFLNWGGMISAIYSKKCYSFAPPFMAGLASMIAMLVQPNMQIRALSWIPLVLDPSIALAMSCIAFNYFRRKHQNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVV4</accession>
    <name>A0A2S9GVV4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000018">
        <property type="protein sequence ID" value="PRC91844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91844">
        <property type="protein sequence ID" value="PRC91844"/>
        <property type="gene ID" value="S2091_3400"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="324" mass="36270" checksum="C701857F63148554" modified="2018-07-18" version="1">MKFFYFSISIICFGAILWLSGCATERNSMRPSTLSQSTQEKIPAASRSNAALAADQNFWDVFHNAKYDEIQPVLEQMTGAYLRDPTDPVTASHIGWLHIWRISERERMAMVTPSITDDAVLARKYFQEASSINPSDARFLGFLAASTLSEGTIHHNEPEISEGNVLMRKAIVAWPEFNLFTAGYMLSTKPVDTAEFKQGLEWQWENLSLCVGEKISRTDPDYSSSVTKITTVGPKRACWNSTVAPHNFEGFFLNMGDMLVKSGDWKVAQKIYTLAKSSPDYSSWKFAPLLEERISNAQSNITPFASNKGLMINSKVSCMACHQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GW52</accession>
    <name>A0A2S9GW52_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ABC-type nitrate/sulfonate/bicarbonate transport systems periplasmic component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3297</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000017">
        <property type="protein sequence ID" value="PRC91955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91955">
        <property type="protein sequence ID" value="PRC91955"/>
        <property type="gene ID" value="S2091_3297"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001638">
        <property type="entry name" value="Solute-binding_3/MltF_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015168">
        <property type="entry name" value="SsuA/THI5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09084">
        <property type="entry name" value="NMT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00062">
        <property type="entry name" value="PBPb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="PBPb" evidence="2">
        <location>
            <begin position="47"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="334" mass="36975" checksum="3BAA8CE81B6748D9" modified="2018-07-18" version="1">MFNKSLLLAAVVAVALITGIFIHYSHFWQPPPSPLPIVILRFQTPHSGLIHIAQAKGYFTDEGLTVTYKTMQVGPEAIARVLSGEADFATTAETPVAMALAEGKHPKFIATIFSSRWSSGIVARKDHGVLTPEDLKGKRIGFVFGTNTQYDLETFLAFHNIPLDSITMVPGLPTELVAELVSGKIDAASVWVPHMTNMQNQLGDNGVTFLRNEAYAQTINIIVRPDYAAHHRKEIDRFLRALYKAEIFTKEHSNEAYNIIASASGVDTSVLRGHGEPLTYELTLKQSLLIATENQVHWFFRRGLVPNGPFPDILDAFETEPLRAIKPTEVTISK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GW67</accession>
    <name>A0A2S9GW67_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RraB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3280</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000017">
        <property type="protein sequence ID" value="PRC91938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91938">
        <property type="protein sequence ID" value="PRC91938"/>
        <property type="gene ID" value="S2091_3280"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.970">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036701">
        <property type="entry name" value="RraB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009671">
        <property type="entry name" value="RraB_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06877">
        <property type="entry name" value="RraB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89946">
        <property type="entry name" value="SSF89946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RraB" evidence="1">
        <location>
            <begin position="37"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="137" mass="15880" checksum="D99711ADAE012BEC" modified="2018-07-18" version="1">MKKIFIRLIALFVLLSVFDLASAKDKIVITLEQLNKMFVSMRSDLGDKVDGDLLWGYFFTDSDPKKLQPLADRLSKNGYRVVNIYLTDDKNKYFLHIEKIEHHTPESLNKRNAEFYKLANEFQLESYDGMDVGPVGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GW72</accession>
    <name>A0A2S9GW72_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Dimethylhistidine N-methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_3306</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000017">
        <property type="protein sequence ID" value="PRC91964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91964">
        <property type="protein sequence ID" value="PRC91964"/>
        <property type="gene ID" value="S2091_3306"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035094">
        <property type="entry name" value="EgtD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019257">
        <property type="entry name" value="MeTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017804">
        <property type="entry name" value="MeTrfase_EgtD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10017">
        <property type="entry name" value="Methyltransf_33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018005">
        <property type="entry name" value="UCP018005"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03438">
        <property type="entry name" value="egtD_ergothio"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_33" evidence="3">
        <location>
            <begin position="26"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF10017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC91964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="325" mass="36662" checksum="EEFE36384B45F0E3" modified="2018-07-18" version="1">MDLATSVNVAIADRDHALDTKEFTIQELTTGLLSDHATISPKYFYDTVGSVLFETICVLPEYYPTRTEAGIFTRHLTDISQTIGPGGTLIDLGAGNCAKAARLFPFLHPDQYVPIDISVNHLTDSVRHLRQRFPHIEMTALGMDFSKNWTLPDEVRSDQRLFFYPGSSIGNFHPDIALTFLKKIRAACDADGGILIGIDLIKDSATLNAAYDDDLGVTAAFNLNALRHVNQLLGSDFDIRQWQHYAFFNAQQSRIEMHLEARMNLQVKWGNNHRHFIRGERIHTENSYKYSLPLFLELLSAAGFGKARHWSDDANWYAVIYAKAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GW84</accession>
    <name>A0A2S9GW84_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Zn-dependent dipeptidase microsomal dipeptidase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3316</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000017">
        <property type="protein sequence ID" value="PRC91974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91974">
        <property type="protein sequence ID" value="PRC91974"/>
        <property type="gene ID" value="S2091_3316"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070573">
        <property type="term" value="F:metallodipeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008257">
        <property type="entry name" value="Pept_M19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10443">
        <property type="entry name" value="PTHR10443"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01244">
        <property type="entry name" value="Peptidase_M19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51365">
        <property type="entry name" value="RENAL_DIPEPTIDASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="323" mass="35743" checksum="A2AD0D31ABEFF6CC" modified="2018-07-18" version="1">MSNLHDSATIIDGLIIAKWERSIFEDMRRGGLTAANCTVSVWEGFSDTVANIADMKKLMRENSELVSLVRSTKDIQDAKQNGKTGIILGFQNAHAFEDNLGYIEAFADMGVRVVQICYNTQNLIGTGCYERDGGLSGFGREAIAEMNRVGIMVDLSHVGGATSEEAILASAKPVCYSHCLPSGLKEHPRNKSDEQLRFIADHGGFIGVTMFPPFLKRGIEATVTDYVEAIDYVINLVGEDCVGVGTDFTQGYDKGFFDWITHDKGRYRQLTKFGTILNPLGIRTIGEFPNLTDAMEKAGWTESRIRKVMGDNWVRTFKEVWGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWG0</accession>
    <name>A0A2S9GWG0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3185</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000016">
        <property type="protein sequence ID" value="PRC92050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92050">
        <property type="protein sequence ID" value="PRC92050"/>
        <property type="gene ID" value="S2091_3185"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001845">
        <property type="entry name" value="HTH_ArsR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00778">
        <property type="entry name" value="HTHARSR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00418">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50987">
        <property type="entry name" value="HTH_ARSR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH arsR-type" evidence="1">
        <location>
            <begin position="1"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="107" mass="12155" checksum="77951C3D7B8F0ECE" modified="2018-07-18" version="1">MHAEPTAVLKILSDPTRRAIFERLSRDGEMTVHALTDPSGVSQPAISKHLAALNQAGLVRGRRAGRETYYSAEPKALAPLINWINFYSTFWDNQFDRLEDLLKRMDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWY5</accession>
    <name>A0A2S9GWY5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">HAD-SF-IIIA: HAD hydrolase, family IIIA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3150</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92234">
        <property type="protein sequence ID" value="PRC92234"/>
        <property type="gene ID" value="S2091_3150"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006549">
        <property type="entry name" value="HAD-SF_hydro_IIIA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041492">
        <property type="entry name" value="HAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13419">
        <property type="entry name" value="HAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01549">
        <property type="entry name" value="HAD-SF-IA-v1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01662">
        <property type="entry name" value="HAD-SF-IIIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="219" mass="24362" checksum="B2F240ECBC344521" modified="2018-07-18" version="1">MVKRKYDLIVFDWDGTLMDSTATIVKCIQAAARDLNLPIPSAESASYVIGLSLFDAMQAVMPDVDAKHYPRMVERYRYHYLTQDEELVLFDGVKEMLTELSQSGYFLAVATGKSRVGLNRALDASKLLSVFDATRCADETFSKPHPAMLLELTRELGQDIKRTVMIGDTTHDLLMAGNAGADAVAVNYGAHPTEVLQELNPMYMANTVPMLHAWLRENA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GX61</accession>
    <name>A0A2S9GX61_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NADH:flavin oxidoreductases Old Yellow Enzyme family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2962</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92303">
        <property type="protein sequence ID" value="PRC92303"/>
        <property type="gene ID" value="S2091_2962"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001155">
        <property type="entry name" value="OxRdtase_FMN_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045247">
        <property type="entry name" value="Oye-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22893">
        <property type="entry name" value="PTHR22893"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00724">
        <property type="entry name" value="Oxidored_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Oxidored_FMN" evidence="1">
        <location>
            <begin position="4"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="351" mass="37401" checksum="B9092C6B168B43DC" modified="2018-07-18" version="1">MSALFNPIRIGDLDLPNRIIMAPLTRARAVGKGRVPNELMAQYYAQRASAGLIISEATSVTPQGVGYADTPGLWSAEQVAGWKQVTSAVHAAGGRILAQLWHVGRVSDPIFLDDELPVAPSAIAVEGHVSLLRPERPYVTPRALEIDELPGIIAAFRQGAENAKAAGFDGVEIHGANGYLLDQFLQDGSNKRADIYGGSIENRARLLLEVTDACISVWGASRVGVHLAPRGGYYSMSDSNPAATFGYVARQLGERGIAFIFSRDALVDAPLSAELKKAFGGTYIANEQLTGTTAEQILADGSADAIAFGRLFIANPDLPRRLLVGAPLNEQRPETFMTAGAEGYIDYPALA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXI3</accession>
    <name>A0A2S9GXI3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2810</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92435">
        <property type="protein sequence ID" value="PRC92435"/>
        <property type="gene ID" value="S2091_2810"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="104" mass="11771" checksum="3BCC836884D488FD" modified="2018-07-18" version="1">MNHISADPRLWDKHAPTHENGAAKHTVRITPRGVKMHFSVNTNHITELRHLIMTTCGDLLIFMQIQPVEHATRMQVELCMKIPALQRVTAAIQHTSMNVALTCI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXP3</accession>
    <name>A0A2S9GXP3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Response regulator of the LytR/AlgR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_2867</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92492">
        <property type="protein sequence ID" value="PRC92492"/>
        <property type="gene ID" value="S2091_2867"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007492">
        <property type="entry name" value="LytTR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04397">
        <property type="entry name" value="LytTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00850">
        <property type="entry name" value="LytTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50930">
        <property type="entry name" value="HTH_LYTTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="15"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="domain" description="HTH LytTR-type" evidence="3">
        <location>
            <begin position="166"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC92492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="275" mass="31135" checksum="11069A3317F43A60" modified="2018-07-18" version="1">MIDNNHTTTDFAINRAIIVDDEESGRIMLRYALSAKKNWVIVGEFNNVAAAREFLKTQEVDVIFLDIQMPRENGTGLARSVSDMERPPLIIFVTAFNTHAIEAFEVHALDYLLKPVGPARFTQALSRADEILTQRRGYAKALRSYVDREEQANDTITNAGNYLQQIVARSVGEMECIALSEVLWMSSAGNYVELHLDKRVVLHRMALSAIEKLINPKDFIRVHRSAIVRTDQFQHIKVIGDGSYRLTLLCGAEVTVSERHIEQVRGFFKELQGSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXR7</accession>
    <name>A0A2S9GXR7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2876</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92501">
        <property type="protein sequence ID" value="PRC92501"/>
        <property type="gene ID" value="S2091_2876"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="186"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="206" mass="23677" checksum="DAA601B42BEDD845" modified="2018-07-18" version="1">MQAKDYVGAQKVMAEAGQLYDMTCPLVTYFEPYWAFAAAKINDTAYIENLPTLFHQDDRQFDYHLTKSVLQAFKHDVDGSIESAHMAKLFVTNNLATGFLPDYSYAEIMEWLYFETKNEKYRVEVLDWVAKVEKKLPWAGWAYAMEAELQSDPVIRSNAAAMARYLDPLSERLARLPKNVRDDAKFTNGNPLLKPVDRGQRMEGKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXY1</accession>
    <name>A0A2S9GXY1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2628</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92573">
        <property type="protein sequence ID" value="PRC92573"/>
        <property type="gene ID" value="S2091_2628"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="155" mass="17277" checksum="37D8AFCDED9240BD" modified="2018-07-18" version="1">MNKPTIQISREIFSNEKFPPHGKFSASLDGQLIHMEATGPFNFELLSAYYEATLPMYVEAHSHGAYAVLVEFHRSMLMNCEAVQLLAESVARLVRNDNVMIAVAYVSGLEVEGQSVMVPYIQKNVFEANGIVFKVFNAVADAEIWLHQLLADGVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GY86</accession>
    <name>A0A2S9GY86_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Prophage tail length tape measure protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2734</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92679">
        <property type="protein sequence ID" value="PRC92679"/>
        <property type="gene ID" value="S2091_2734"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009628">
        <property type="entry name" value="Phage_tape_measure_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06791">
        <property type="entry name" value="TMP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TMP_2" evidence="2">
        <location>
            <begin position="130"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="929"/>
            <end position="948"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="1566" mass="161698" checksum="32EF97C5C8E16178" modified="2018-07-18" version="1">MSDSVDIQTLGIAVVATGATEATAQVKDFGDAANAAGEKVKGVTAPLAQLNENLTITERAAAAAAASANRLAIEQQALGRSTSDLSIGAQVYLDKLREQALAAQSGLSSMAAQAEALGIAKSEYEPLIEQIEAATASSHKLSFATAGVTRELGVMAGEIARGNYARLEGSMMTLANRTGLLTMLLDPLVLGVAAVGGAFIAAGVLAIKGAEEFNAINLALNNTGNSAGRTAAQLMDMSKRVGGASGDIGQAREALTLLAATGRISGDNLEEFGNIAVAMAKSTGSSVGDVVKSLAGLSDDALKWSENYQKQHHFMTGAAYDLIKSLHDEGDEAAAVSVVLQTLEEYNNRMAPPKEAGTISKWWESWVDVIHQASEGLKSIGVPNSNFEQINIALQKRTELETTLNSAKSSSSATYIAQIQGELNANLSLINSLRDVGKAELQKAKDQQTAGASGDHKIVNEAYLSSSQNASPALQQAQALLKDTAAYKQAIIGYKSTDEEYILAVQRHNANQAAIVDSFSTKDKLSDYDKLTDSLKVQLAEQELLLSADGKLSAGEKERAKILQELNNGTISLTASQLESVQAKLAEIIADQQALQIKNDDIKAAETLAATRQKAIDSLITQAEKLENSSKVQGKANSLIEEETSRRNANELAVKKETLALMEQQNIGSPNSSMGKDIDAIKLEIDYLGQLSAAQHRVATDMSLSEQATAADKASKELDKYLDPHRAQQFGASMKAAFGSAGAALGGLIDALGKYDKAQEESDKARINAKKELDAHAVTDIQYQQRLADITNMQAQQQIGSYADMAQAASGYFDKNSTGYTIMQDAEKAYRAISAALAMEDFLVKSGLQTSFLGLFAASKATAAAIDTAATGDSVANSMIRASADGIAAFVKTLASIPYPFNLVAAASVAAIVVGMGVKLSAAHAGGESTSASDQAATGTGTVLGDPTGKSDSVNASLKLIAANSTSQLSQTGQLLTAFNSLSATLANMTTTILQSAGIGIAGGVNSPVSLTANSSEANSLNSMLNTVRLGVGDSITTKITNAVSNAIFGGSQTLTGQGISSNNATVAQVAAGGFQASSYANISTSGGWFHGDSNSTQTNSLGSATNQQFSLAIGQMASSISDAASLIGISGPAFTANLNNFVVSIGKIDTKGMTTTQVEAALQTAFAAMGDKMATWAVAGIGKFTQAGEGALQTLVRVATDYATIDSDLAGVGMTFGAVGLASVGARENLISLAGGLTTLTSGIQFVQSNFMNQAQQSAPLVADLTQKMGALGLGAITTQAQFLALYQSLNLNTAAGQSMLVSLNQIAPEFQQVSDYQTALAAGTLKLTSQQTAAQTTLQNAYSAQATALNSVISAMGSFATATDQFRTSLQLGSLSTLTPAQQYAAAQQQYQSVLGNLNSSDPTTQANAQGQLQSASTAFLTASQTYNASSVQYQSDYAKVQANLAAVVTGATAQSNTATQQLAALNTQVAGLITVNASVLTVQQGTIAVTNAVNAMNASLGTNLTAAVNALIAQVAAQSNAQAAQTAASIAANNIANANAAKTIADRLDVFNPTNGRTRIQLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GY91</accession>
    <name>A0A2S9GY91_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2738</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92683">
        <property type="protein sequence ID" value="PRC92683"/>
        <property type="gene ID" value="S2091_2738"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="80" mass="8734" checksum="9B599E8FA16E15B0" modified="2018-07-18" version="1">MEQLKAYLWNILVSLDRVVNTMLGGSPEMTLSGRMGRDIALGECALCKPICWLLNKIQSNHCAMAASNESTFGSDAISKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYF7</accession>
    <name>A0A2S9GYF7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2473</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92743">
        <property type="protein sequence ID" value="PRC92743"/>
        <property type="gene ID" value="S2091_2473"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="1023" mass="117136" checksum="381128F948433816" modified="2018-07-18" version="1">MPVIPSSAKSVGDETFHDIFFALLAQQLQKISTVILSTGNQINNADEFFSSSVKVLEYAAFQIASDLKAGIRLDSFEIYKIALQSEIPRTRSYDHELKTTEFAFEHALGRIFVHLHILLGESRIEPINSSSLENLSINPWWNPQSWLKFVSAWTPNIIPATMSDQIIASCIKTLRVERSNTSTLANNSLELARLALALKREAIGRECLVLAARHTLGYGWRKDTTFSELFDAIQFCSGHGVGNIADWLRRVAPFVDDVFDFSEREIRHIPGWYVKLLAKHVPERIVDEFEYHMKQQNWGILPNILENFVVQSDLNSVADTFFLKCLASHECIEAIAKRSETDTRFTRLLEEQKMYFGGEPMAPRDESSTPTERKPIEIEYSKFQPDNLNELYIELKDELKVYDADEFINSWISYWNDAGCGVELVSAFERFWDRHTEFPYLMRRALGRIFSLSHKLQGARKAYKWAVRDIRANNHWARWSGRLAEESLNKYGRIYSAEWQTLLTDTTVGEQIGVRENGWIIVPSCQLISYLLEAEQSDLACQITEIMVSSLEDEISHLPISPLHWQKVPVPIEQISARLLLLYYKWPDRYVRRRTSMQIAELLNNDMDFRPLYLEHLSAQKYETDISDLLSILTLTDQNLFSGEELSTAIKFPSILSRQILRELGYKSQNESTSKYFSALTAADYSDSSLITRSRDGIAPVYFSTINGLGRKLNYPLEKHLTAEWNLISARQPFLFFSPYDFSGDYFYRQDPIACSFSTNAETLLTSASLRTLAFASDAYELSTEQIALYAANLLPFSNLLGKLLPASKPKNWPKFDTFEKNEALPSKEDLDDMLYRLSSTDMVILCANGPVSREISGVNCDLSIYTVFVENEYFDDPKRLYLSASGAIKSDEISVYPLATNAFPNYLGRFEIDFLLRGLFQPEFSIGNGSRTIISENDSLSYISDDKCCAKWKYWADSWYPVFPKDIGPALGTYLETPRKVFDQLTQDLDGSSYMVANLTILDKRDYLREGNKTEIYALRLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYK5</accession>
    <name>A0A2S9GYK5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Superfamily II DNA and RNA helicase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">S2091_2537</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the DEAD box helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92807">
        <property type="protein sequence ID" value="PRC92807"/>
        <property type="gene ID" value="S2091_2537"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 6 11" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Q_MOTIF" evidence="10">
        <location>
            <begin position="33"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="8">
        <location>
            <begin position="64"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="9">
        <location>
            <begin position="253"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="419"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="5">
        <location>
            <begin position="33"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="462"/>
            <end position="484"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC92807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="498" mass="53891" checksum="4B02F98F008DC2FF" modified="2018-07-18" version="1">MTEIKSELNSELSTELSSITISTSSSAEVAADVRFADFGLSDDILRALSDQGYVHPTPIQAAAIPVVLEGRDVMGAAQTGTGKTAGFSLPIIQLLLAHANASASPARHPVRALILTPTRELADQVAENVKAYCKHTPLRSLVVFGGVDIAPQTAALRAGVEIVIATPGRLLDHVQQKTINLSQVQILVMDEADRMLDMGFLPDLQRIINLLPKARQSLMFSATFSQEIKKLAATFLRNPLTIEVARSNATAENVTQILYQVQEEEKRDAVSFIIRERNLKQVIVFSNTKIGTSRLAVHLVKTGVKAAAIHGDKTQQERMAALESFKRGEIEVLVATDVAARGLDIAELPCVINFDLPYNAEDYVHRIGRTGRAGATGDAISLFTEKDERLLADIEKLIKQKIVRLHLAGFVATKLEPHGLREPRSSGARSSSSGSAEVKNDRRVAPRSYASTPKIDPWFLQPYQPTASTLPVAEKPSVTSSSGKPAKRAALLGGFSKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYV3</accession>
    <name>A0A2S9GYV3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Membrane dipeptidase (Peptidase family M19)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2308</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92891">
        <property type="protein sequence ID" value="PRC92891"/>
        <property type="gene ID" value="S2091_2308"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070573">
        <property type="term" value="F:metallodipeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008257">
        <property type="entry name" value="Pept_M19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10443">
        <property type="entry name" value="PTHR10443"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01244">
        <property type="entry name" value="Peptidase_M19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51365">
        <property type="entry name" value="RENAL_DIPEPTIDASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="403" mass="44659" checksum="D7379EF077E1CA03" modified="2018-07-18" version="1">MTEKIISINPFQNRMINANDHQTSIYAHRRSLFYQAPLSLPASSENTLPLETNAMKEQPIIIDTSGSITNLNLTPAQQKDEFTMGIDQRSINEALASGLTAINMTMGYVFGKEDPFEQTVRQIAAWDALIRRTPESLRKVWTVKDIQAAHTNKQVGVIYGFQNAVMMGDNEHRVEIFANLGVRFIQLTYNTRNSLGDGSMMPENQGLTEFGRKVVHELNRHHVLVDLSHSGEQTCLDAIAASSQPTIISHTGCRALTNLPRNKTDRELRLVAESGGFVGIYFMPFLAIGRQFTSEDLIAHIEHAVNVCGEDHVGIGTDGSVTKIDDMQGYMTELKNEVDHRHATGIAATGERADIVPFLSDLSGTNKFMELADMLAKRGHSSGRIEKILGSNFMNAADRIWSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZ35</accession>
    <name>A0A2S9GZ35_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2402</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92985">
        <property type="protein sequence ID" value="PRC92985"/>
        <property type="gene ID" value="S2091_2402"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007751">
        <property type="entry name" value="DUF676_lipase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05057">
        <property type="entry name" value="DUF676"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF676" evidence="1">
        <location>
            <begin position="41"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="217" mass="23617" checksum="F82C465E0C7B7C7C" modified="2018-07-18" version="1">MTASRQAQNMVVLFVHGMGRTPISGLAMLHLLRRAGMQTSSFCYSTAFDDFRSIQERLVARITSLAASENYIVVGHSLGGVLLRAALNSLPANTNRPRHIFLLGSPIHPSRLAQRLKHNILFRALAGDCGQLLSSSERMDQVGALNEPTTSIVGVRGVVITKMFFGDAPNDGVVSVAEASATWISDQRQVSTVHMLLPSSRRVAEIICKTVFENSDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZM2</accession>
    <name>A0A2S9GZM2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Chloride channel protein EriC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_2268</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93182">
        <property type="protein sequence ID" value="PRC93182"/>
        <property type="gene ID" value="S2091_2268"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005247">
        <property type="term" value="F:voltage-gated chloride channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014743">
        <property type="entry name" value="Cl-channel_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001807">
        <property type="entry name" value="Cl-channel_volt-gated"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00654">
        <property type="entry name" value="Voltage_CLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00762">
        <property type="entry name" value="CLCHANNEL"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81340">
        <property type="entry name" value="SSF81340"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0129">CBS domain</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="67"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="165"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="201"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="231"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="272"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="309"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="337"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="363"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="396"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="7">
        <location>
            <begin position="449"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="7">
        <location>
            <begin position="515"/>
            <end position="577"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC93182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="582" mass="62379" checksum="29F358088B5B1EB7" modified="2018-07-18" version="1">MSSYLNQHKRDFSNDKRLLKISCIAIAIGACGTLAAWLLLNLIRLFTNLFFYQAFSFVTRSPANHHLGAWVICLPVLGGLIVGLIARFGSEKIRGHGIPEAIEAILFGKSKMSAKVAILKPISSGIVIGSGGPFGAEGPIIMTGGAIGSLIAQHFHLTAAERKTLLVAGATAGMTAVFGTPIAAVLLAVELLLFELRPRSLLPVIVACSVAGFTRPLLLDSGPLFPLQTPAVGLLALFSCVIAGLLGGALSALMSTMLYRVEDAFHKLPVHWMWWPALGGLVVGIGGYFEPRALGVGYDVIGDLLNNHLLLQVALGLLLAKSVMWVIALGSGTSGGVLAPLLIIGAGLGTVLAPWLPGGDVHLWPLVCMAAVLAGVLGAPLTAAVFAFGLTQDVNALLPLLLTTGVAYGFTVLTMKRSIMTEKISRRGYHIYREYGVDPMERQHVDEVMSHVVTTISAQLSIAAALDQFFGAQQSHRSYPVVDDDQRLIGMIERSSLKQLADESSSLIHLFDAQQQTNVHFALPTETCRVAAARMATLQLERLPVVNNLKDRRVIGIISRSDLIKPSQLFFDEEQKRERLIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZT1</accession>
    <name>A0A2S9GZT1_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Phosphoheptose isomerase</fullName>
            <ecNumber evidence="9">5.3.1.28</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Sedoheptulose 7-phosphate isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">gmhA</name>
        <name evidence="11" type="ORF">S2091_1980</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>2 D-sedoheptulose 7-phosphate = D-glycero-alpha-D-manno-heptose 7-phosphate + D-glycero-beta-D-manno-heptose 7-phosphate</text>
            <dbReference type="Rhea" id="RHEA:27489"/>
            <dbReference type="ChEBI" id="CHEBI:57483"/>
            <dbReference type="ChEBI" id="CHEBI:60203"/>
            <dbReference type="ChEBI" id="CHEBI:60204"/>
            <dbReference type="EC" id="5.3.1.28"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="9">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="9">Carbohydrate biosynthesis; D-glycero-D-manno-heptose 7-phosphate biosynthesis; D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate from sedoheptulose 7-phosphate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="9">The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the SIS family. GmhA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.28" evidence="9"/>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93242">
        <property type="protein sequence ID" value="PRC93242"/>
        <property type="gene ID" value="S2091_1980"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00041">
        <property type="reaction ID" value="UER00436"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097367">
        <property type="term" value="F:carbohydrate derivative binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008968">
        <property type="term" value="F:D-sedoheptulose 7-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:2001061">
        <property type="term" value="P:D-glycero-D-manno-heptose 7-phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd05006">
        <property type="entry name" value="SIS_GmhA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00067">
        <property type="entry name" value="GmhA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035461">
        <property type="entry name" value="GmhA/DiaA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004515">
        <property type="entry name" value="Phosphoheptose_Isoase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001347">
        <property type="entry name" value="SIS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046348">
        <property type="entry name" value="SIS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13580">
        <property type="entry name" value="SIS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53697">
        <property type="entry name" value="SSF53697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51464">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="4 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 9 11" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="SIS" evidence="10">
        <location>
            <begin position="35"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="9">
        <location>
            <begin position="50"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="9">
        <location>
            <begin position="92"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="9">
        <location>
            <begin position="118"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="59"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="63"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="123"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="173"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="181"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC93242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="198" mass="21060" checksum="6B578F1E17386414" modified="2018-07-18" version="1">MTNQQILMHFRESAELKMQAAEQLADPISKAVEIMFTALSNGNKILACGNGGSAADCQHFAAELVGRFERERLPLPAMALTTDSSIMTAVGNDYSFAEVYSKQVQAFGQAGDVLLAISTSGNSGNVVQAVQAALEREMHVVALTGKNGGVIATLLGESDVNICVPHERTARIQEVHLLTIHCICDGIDNALFGGEVNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZU8</accession>
    <name>A0A2S9GZU8_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ATP-dependent zinc metalloprotease FtsH</fullName>
            <ecNumber evidence="5">3.4.24.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ftsH</name>
        <name evidence="9" type="ORF">S2091_2232</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="5">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homohexamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
            <orientation evidence="5">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">In the C-terminal section; belongs to the peptidase M41 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">In the central section; belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="5"/>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93146">
        <property type="protein sequence ID" value="PRC93146"/>
        <property type="gene ID" value="S2091_2232"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030163">
        <property type="term" value="P:protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01458">
        <property type="entry name" value="FtsH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005936">
        <property type="entry name" value="FtsH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011546">
        <property type="entry name" value="Pept_M41_FtsH_extracell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000642">
        <property type="entry name" value="Peptidase_M41"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037219">
        <property type="entry name" value="Peptidase_M41-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06480">
        <property type="entry name" value="FtsH_ext"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01434">
        <property type="entry name" value="Peptidase_M41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140990">
        <property type="entry name" value="SSF140990"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01241">
        <property type="entry name" value="FtsH_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 5" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="5 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2 5" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="103"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="AAA" evidence="8">
        <location>
            <begin position="189"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="594"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="420"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="197"/>
            <end position="204"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="419"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="423"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="495"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC93146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="624" mass="68122" checksum="1B813FC00C1D708A" modified="2018-07-18" version="1">MNNMFSKAAIWVVVAMVLFMVFKQFDGKGLSAGAAPIAYSDFLDQVKSKQLKEVVIEDGNITAVTQDGNKVKTTATALDRGLIGDLVSSGIKFDIKRAEEPSLLIQLLMSYGPMLLLIGVWIFFMRQMQGGGKGGAFSFGKSKARMLDETTNNVSFADVAGCDEAKEEVQEVVEFLRDPTKFQKLGGRIPRGVLMVGPPGTGKTLLARAIAGEAKVPFFTISGSDFVEMFVGVGASRVRDMFENAKKHAPCIIFIDEIDAVGRHRGAGMGGGNDEREQTLNQMLVEMDGFEPNSGVIVIAATNRADVLDKALLRPGRFDRQVTVGLPDIRGREQILNVHMRKVPIAPDVKADILARGTPGFSGADLANLVNESALFAARRNKRLVEMQDFEDAKDKIYMGPERKSMVMREDERRNTAYHESGHAVVASLLPKADPVHKVTIMPRGNALGLTWQLPEHDQISGYKDKMLGEITILFGGRIAEEIFVGQMSTGASNDFSRATKLARAMVTRFGMSEKLGVMVYEDSQQEGYFGGASKTISEATQQTVDAEIRRILDTQYAQSRQLLEENRDKVEAMTKALLDWETIDADQIGDIMQGIEPRPPKVSGSVRKPSSGDGIAPSVTATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZV5</accession>
    <name>A0A2S9GZV5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">PEP-CTERM protein-sorting domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_2002</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93264">
        <property type="protein sequence ID" value="PRC93264"/>
        <property type="gene ID" value="S2091_2002"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013424">
        <property type="entry name" value="PEP_exosort_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07589">
        <property type="entry name" value="PEP-CTERM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02595">
        <property type="entry name" value="PEP_exosort"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015429557" evidence="2">
        <location>
            <begin position="26"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="domain" description="PEP-CTERM" evidence="3">
        <location>
            <begin position="304"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="157"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC93264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="331" mass="30372" checksum="B3A68BD66463E04E" modified="2018-07-18" version="1">MNTRNQTFVKKALFAMMFVGASAQAVPFTYTGSIVDYTITTSGVYDLTAAGAQGGSGNGVGTTGGLGAQISGDLFLTTGTQLGIVVGGQGLTGNFGGLAGGGGGGGSFVYIIGSTSPLIVAGGGGGAGYIDATVGGGGQTTTSGQAGFGAGGGAGGSAGSGGAGGNDEIGDNGGGGGGWGGNGGDGVGTTYTQTGGAGLGGAGAFSFLAGFGDCDPSVPACANGGFGGGGGGGWQGGGGGGGYSGGGGGDGTTDGGGGGGSYIDASFLSIGSMIGGSDTSDNGAPLGNANNGFVNIDMVLLSNPVPEPLTLALMAIGLAGLGFIRRKKARI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H034</accession>
    <name>A0A2S9H034_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fimbrial protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2087</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93349">
        <property type="protein sequence ID" value="PRC93349"/>
        <property type="gene ID" value="S2091_2087"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009289">
        <property type="term" value="C:pilus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007155">
        <property type="term" value="P:cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1090">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000259">
        <property type="entry name" value="Adhesion_dom_fimbrial"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036937">
        <property type="entry name" value="Adhesion_dom_fimbrial_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008966">
        <property type="entry name" value="Adhesion_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00419">
        <property type="entry name" value="Fimbrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49401">
        <property type="entry name" value="SSF49401"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015655580" evidence="1">
        <location>
            <begin position="28"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="domain" description="Fimbrial" evidence="2">
        <location>
            <begin position="188"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="342" mass="35274" checksum="63C0B9A8DBBEA06F" modified="2018-07-18" version="1">MLKRVWRFSLIKICMLMLLLTSWQAFASCSQNPVAGTKFITAPGTISINPYQTNGLPVANGTVLYTGTFTGNTGNFTVTCTAAFTGLLYQGIGTATANVYPTSIPGIGMEIHNTGSANDNLWPAAVTVASSTSYSSTASAEVTLQLVKTGPITTGGTLSGTVGNYVIPTQANYSIFPIALTGVTIVGLTQPTCVVTSTTINVALGNFAINHFPAIGSTSPPMPFNIQLVCSGGPGVTTTTMSTVLTDATNSANTSNTLPLSASSTATGLGVQITYNGAIVSYAADPSVNPVATFVPPYPNQVTLGTGENGTYNFPFYAHYIRTGTVTAGTANSSATFTIIYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H038</accession>
    <name>A0A2S9H038_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative translation initiation inhibitor yjgF family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2079</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93341">
        <property type="protein sequence ID" value="PRC93341"/>
        <property type="gene ID" value="S2091_2079"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035959">
        <property type="entry name" value="RutC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006175">
        <property type="entry name" value="YjgF/YER057c/UK114"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01042">
        <property type="entry name" value="Ribonuc_L-PSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55298">
        <property type="entry name" value="SSF55298"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="129" mass="14100" checksum="F211E980B47C3F92" modified="2018-07-18" version="1">MSKKLISSGSDFEKLAGYSRAVVEHGLVHVSGTTGFNYDAMTIDADLIDQTHQIFKNIEAALKQAGAGLDDVVRVHYLITDASYFEQVAPIFGQYFVNARPAATAMVVGLIDPRMKIEIEVTARLPNLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H063</accession>
    <name>A0A2S9H063_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Rubredoxin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_1759</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>Fe(3+)</name>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the rubredoxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93372">
        <property type="protein sequence ID" value="PRC93372"/>
        <property type="gene ID" value="S2091_1759"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00730">
        <property type="entry name" value="rubredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024934">
        <property type="entry name" value="Rubredoxin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024935">
        <property type="entry name" value="Rubredoxin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018527">
        <property type="entry name" value="Rubredoxin_Fe_BS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00301">
        <property type="entry name" value="Rubredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00163">
        <property type="entry name" value="RUBREDOXIN"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00202">
        <property type="entry name" value="RUBREDOXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50903">
        <property type="entry name" value="RUBREDOXIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0249">Electron transport</keyword>
    <keyword evidence="5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Rubredoxin-like" evidence="7">
        <location>
            <begin position="13"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC93372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="64" mass="7428" checksum="9514580DDA499B64" modified="2018-07-18" version="1">MFPTFKHKPKQEYKSYICTICGYVYDEAKGCLESKVEAGTRWDDLTEDWECPHCDGGKEDFNAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0M5</accession>
    <name>A0A2S9H0M5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Polysaccharide deacetylase family protein, PEP-CTERM locus subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1919</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93532">
        <property type="protein sequence ID" value="PRC93532"/>
        <property type="gene ID" value="S2091_1919"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd10941">
        <property type="entry name" value="CE4_PuuE_HpPgdA_like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045235">
        <property type="entry name" value="CE4_PuuE_HpPgdA-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022560">
        <property type="entry name" value="DUF3473"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002509">
        <property type="entry name" value="NODB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014344">
        <property type="entry name" value="PEP-CTERM_polysacc_deacetyl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11959">
        <property type="entry name" value="DUF3473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01522">
        <property type="entry name" value="Polysacc_deac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="SSF88713"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03006">
        <property type="entry name" value="pepcterm_polyde"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51677">
        <property type="entry name" value="NODB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NodB homology" evidence="1">
        <location>
            <begin position="24"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="285" mass="32545" checksum="3D74D0E48CAA845B" modified="2018-07-18" version="1">MNSPATKPICNAMTIDVEDYFQVSAFANHISRDSWPSQTCRVERNVDLILGLLDAAQVNATFFTLGWIAERYPAMIKKIVAGGHELASHGYGHLRVSDQSEAEFMEDISSSKHLLEDLGGQKILGYRAPSFSIGTKNLWALDTLLKAGYRYSSSIYPIKHDHYGMPDAPRFAFYPNGADGLLELPITTVRIMQRNYPAGGGGFFRLLPYPISHWLIQRVNQQDKQPGIFYFHPWEVDPDQPRQQNIGLKTRFRHYVNLSRTESRLKSLTRDFKWGRMDKIFLTKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0N1</accession>
    <name>A0A2S9H0N1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative glycosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_1545</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93544">
        <property type="protein sequence ID" value="PRC93544"/>
        <property type="gene ID" value="S2091_1545"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="244"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_trans_2-like" evidence="3">
        <location>
            <begin position="4"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC93544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="316" mass="35529" checksum="67B8C2D2CE39DC6E" modified="2018-07-18" version="1">MAVTVIIVNWNSSSLLTQCLQHLSLQTVLPKQVIVVDNASFDGSAKNVESFENVILFQMTSNLGFAAGNNRALAECKDEFVALLNPDAFPESDWLENLLIAATNYPDVAAFGSRQLCQANPEFLDGIGDSYHLSGLVWRDRYGVKQQKKHLRAMEIFSPCAAAALYRRQALVDVDGFDEDYFCYVEDIDLGFRLRLAGHKARYVPNAVVHHVGSATTGGQHSDFSIYHGHRNLVWTYIKNMPGYLFWILLPLHIGLNFISIVWFVLNGHSGAILSAKWDALSGLPKMWSKRKFIQKRRVASIGVIWKHLNKSIFLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0S4</accession>
    <name>A0A2S9H0S4_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CENP-V/GFA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_1585</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Gfa family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93584">
        <property type="protein sequence ID" value="PRC93584"/>
        <property type="gene ID" value="S2091_1585"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016846">
        <property type="term" value="F:carbon-sulfur lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006913">
        <property type="entry name" value="CENP-V/GFA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011057">
        <property type="entry name" value="Mss4-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04828">
        <property type="entry name" value="GFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51316">
        <property type="entry name" value="SSF51316"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51891">
        <property type="entry name" value="CENP_V_GFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CENP-V/GFA" evidence="3">
        <location>
            <begin position="14"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC93584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="131" mass="14402" checksum="E8EB670EE6714D4F" modified="2018-07-18" version="1">MIKTVGTTVINAKHKATCHCGAVELLLALPDGIVNPRRCDCSICRRKGAIVASVLLSGITIIKGHDVLKLYQFNTNTAKHYFCSNCGIYTHHQRRSNPKEYGYNVGCLEGVNPFELGEIQTFDGVSHPADR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0S5</accession>
    <name>A0A2S9H0S5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_1853</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93466">
        <property type="protein sequence ID" value="PRC93466"/>
        <property type="gene ID" value="S2091_1853"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="6"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="146"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC93466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="214" mass="22962" checksum="E6E7D69043275A25" modified="2018-07-18" version="1">MSNKIKVLLVDDHAIVRNGVRLMLGEADDISVEGEAGDAQQALQLIRSQEFDVALVDIAMPDKNGLDLLKQLRAEQPKLAVLILSTYSEEIYAMRAFKLGAAGYLTKDSPTSALINAVRKAAAGGKHVSPAMMEKLVSAIGAGGGVGESHEALSNRELEVLKLIASGESLVKIADTLHLSPHTVTTYRARIMEKMNLSNNAELTRYAIENGLLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0U9</accession>
    <name>A0A2S9H0U9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1602</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93601">
        <property type="protein sequence ID" value="PRC93601"/>
        <property type="gene ID" value="S2091_1602"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="115" mass="13864" checksum="7CB94D16C297967B" modified="2018-07-18" version="1">MNFKLRVLKKIVFVVFCIAALSWLVMVLWNWLIPSLFIGAREIDYARAIGLLILSRILFGGLRGHHGHHERHADHEHWHSRWHQHRWEKMTQEEREKFQNGILSARDKHKQENQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0V9</accession>
    <name>A0A2S9H0V9_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Aspartate 1-decarboxylase</fullName>
            <ecNumber evidence="9">4.1.1.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Aspartate alpha-decarboxylase</fullName>
        </alternativeName>
        <component>
            <recommendedName>
                <fullName evidence="9">Aspartate 1-decarboxylase beta chain</fullName>
            </recommendedName>
        </component>
        <component>
            <recommendedName>
                <fullName evidence="9">Aspartate 1-decarboxylase alpha chain</fullName>
            </recommendedName>
        </component>
    </protein>
    <gene>
        <name evidence="9" type="primary">panD</name>
        <name evidence="14" type="ORF">S2091_1612</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>H(+) + L-aspartate = beta-alanine + CO2</text>
            <dbReference type="Rhea" id="RHEA:19497"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:57966"/>
            <dbReference type="EC" id="4.1.1.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9 10">
            <name>pyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
        </cofactor>
        <text evidence="9 10">Binds 1 pyruvoyl group covalently per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="9">Cofactor biosynthesis; (R)-pantothenate biosynthesis; beta-alanine from L-aspartate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Heterooctamer of four alpha and four beta subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="9 12">Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the PanD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.11" evidence="9"/>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93611">
        <property type="protein sequence ID" value="PRC93611"/>
        <property type="gene ID" value="S2091_1612"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00028">
        <property type="reaction ID" value="UER00002"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004068">
        <property type="term" value="F:aspartate 1-decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006523">
        <property type="term" value="P:alanine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015940">
        <property type="term" value="P:pantothenate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06919">
        <property type="entry name" value="Asp_decarbox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00446">
        <property type="entry name" value="PanD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009010">
        <property type="entry name" value="Asp_de-COase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003190">
        <property type="entry name" value="Asp_decarbox"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21012">
        <property type="entry name" value="PTHR21012"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02261">
        <property type="entry name" value="Asp_decarbox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006246">
        <property type="entry name" value="Asp_decarbox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50692">
        <property type="entry name" value="SSF50692"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00223">
        <property type="entry name" value="panD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0068">Autocatalytic cleavage</keyword>
    <keyword evidence="1 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 9" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="6 9" id="KW-0456">Lyase</keyword>
    <keyword evidence="2 9" id="KW-0566">Pantothenate biosynthesis</keyword>
    <keyword evidence="8 9 10" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9 10" id="KW-0704">Schiff base</keyword>
    <keyword evidence="5 9" id="KW-0865">Zymogen</keyword>
    <feature type="chain" id="PRO_5015803030" description="Aspartate 1-decarboxylase beta chain" evidence="9 13">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015803031" description="Aspartate 1-decarboxylase alpha chain" evidence="9 13">
        <location>
            <begin position="25"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="9 11">
        <location>
            <begin position="73"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with substrate; via pyruvic acid" evidence="9 10">
        <location>
            <position position="25"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="9 10">
        <location>
            <position position="58"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9 11">
        <location>
            <position position="57"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="modified residue" description="Pyruvic acid (Ser)" evidence="9 12">
        <location>
            <position position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR006246-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR006246-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR006246-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR006246-5"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="PRC93611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="124" mass="13942" checksum="4822F8F612EE4FA3" modified="2018-07-18" version="1">MQRNMLRAKIHRATVTQCDLNYEGSCGIDENLLDAADILPGERIELYNVNNGERFATYAIKGLRGSGEISLNGAAARRVQLGDLMIICTYAHMTEEYAAKYQPKIVFVDEKNQITGLKKEKLFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H105</accession>
    <name>A0A2S9H105_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1662</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93661">
        <property type="protein sequence ID" value="PRC93661"/>
        <property type="gene ID" value="S2091_1662"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015529478" evidence="2">
        <location>
            <begin position="37"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="93"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="93"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="134"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="151" mass="15879" checksum="8792283CB58B0D69" modified="2018-07-18" version="1">MQHNYCKQPKNIMKTTSKLVLALAFFCIGMAGVAVAAEAPPADTPPKMDNLDEGDPAVTNLKKANVKQTQQTIQNGEQTEVKVTNGIGTYIVKPNQGVGTSLPGDASSSSNHAAQWVIKSWGGSKNTEPADDAPPTLQPNPNAPPSSTPKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H118</accession>
    <name>A0A2S9H118_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">4Fe-4S dicluster domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_1683</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93682">
        <property type="protein sequence ID" value="PRC93682"/>
        <property type="gene ID" value="S2091_1683"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12838">
        <property type="entry name" value="Fer4_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="31"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC93682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="87" mass="9750" checksum="80E39F57D264D268" modified="2018-07-18" version="1">MALLITDDCINCDVCEPECPNDAIYMGPEIYEIDPNKCTECVGHFSEPQCQQVCPVACIPFNPAWRETPEQLQAKYERLQAEAGKPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H135</accession>
    <name>A0A2S9H135_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ribosome-binding ATPase YchF</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ychF</name>
        <name evidence="7" type="ORF">S2091_1679</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93678">
        <property type="protein sequence ID" value="PRC93678"/>
        <property type="gene ID" value="S2091_1679"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043023">
        <property type="term" value="F:ribosomal large subunit binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04867">
        <property type="entry name" value="TGS_YchF_OLA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01900">
        <property type="entry name" value="YchF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00944">
        <property type="entry name" value="YchF_OLA1_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004396">
        <property type="entry name" value="ATPase_YchF/OLA1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031167">
        <property type="entry name" value="G_OBG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004095">
        <property type="entry name" value="TGS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012676">
        <property type="entry name" value="TGS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023192">
        <property type="entry name" value="TGS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013029">
        <property type="entry name" value="YchF_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041706">
        <property type="entry name" value="YchF_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06071">
        <property type="entry name" value="YchF-GTPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006641">
        <property type="entry name" value="CHP00092"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81271">
        <property type="entry name" value="SSF81271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00092">
        <property type="entry name" value="TIGR00092"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51710">
        <property type="entry name" value="G_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51880">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OBG-type G" evidence="5">
        <location>
            <begin position="3"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="domain" description="TGS" evidence="6">
        <location>
            <begin position="278"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="12"/>
            <end position="17"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC93678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="363" mass="39273" checksum="52305EF21FE4F425" modified="2018-07-18" version="1">MALQCGIVGLPNVGKSTLFNALTKAGIPAENYPFCTIEPNVGVVEVPDPRLAQLAHIVKPERIQNAIVEFVDIAGLVAGASKGEGLGNQFLAHIRETDAIVNVVRCFEDDNVIHVAGKVSPLDDIEVIQTELALADMGTVEKAIHREHKKARSGDKDAAKLAELLERIMPALNEAKPVRAMGLDAEEMLLIKPLCLITAKPAMYVANVSDTGFTNNPLLDQLTAYAASQNAPLVAICASIESEIADLEDEDKKAFLEDMGMHEPGLDRLIRAAFKLLGLQTYFTAGVKEVRAWTIHVGDTAPQAAGVIHTDFERGFIRAQTIAFDDFIQFKGEAGAKEAGKMRAEGKEYVVKDGDVLNFLFNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H150</accession>
    <name>A0A2S9H150_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Branched-chain amino acid ABC-type transport system permease component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_1716</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93715">
        <property type="protein sequence ID" value="PRC93715"/>
        <property type="gene ID" value="S2091_1716"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001851">
        <property type="entry name" value="ABC_transp_permease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02653">
        <property type="entry name" value="BPD_transp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="60"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="95"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="135"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="188"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="222"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="257"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC93715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="286" mass="30817" checksum="4E4E301743DA2B5C" modified="2018-07-18" version="1">MNIYLLQIANGIGIGMLYFLLGVGLSIVFGLLRFVNFSHGAFFLLGAYVSFELGQLGLDFWWSLLLAPILVGAFAWLIEKCVLRHIYPLPHHFHILFTVGLALVIQEAVIWYWGPLGNNIAPPELLQGVVILGDFIYPAYRLFVIGFTAVMALLLWWVLEKTRLGSIVRAGSESTEMVSLLGININRIFSLVFALGAFTAGLAGALAAPIRGAEPFMGIEALGIAFVVVVIGGLGSFSGALVAGLLVGIMQSLMSTIWSEGAFLTIYIAMAAVMLLRPNGLLGRAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H180</accession>
    <name>A0A2S9H180_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1746</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93745">
        <property type="protein sequence ID" value="PRC93745"/>
        <property type="gene ID" value="S2091_1746"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="109" mass="12739" checksum="A93D142B3F5D5E22" modified="2018-07-18" version="1">MYCATFIFKKKQFDDEFYQLDQSIAEFARQTTDYIGEETSENLETGCVSNMYYWRTMEGMQELMQHPKHLQAKAAQTNWLDGYQVVISQVLRCYGDGTIPHPTESFINS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1A1</accession>
    <name>A0A2S9H1A1_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">D,D-heptose 1,7-bisphosphate phosphatase</fullName>
            <ecNumber evidence="7">3.1.3.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">S2091_1371</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="3">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the gmhB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.-" evidence="7"/>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93762">
        <property type="protein sequence ID" value="PRC93762"/>
        <property type="gene ID" value="S2091_1371"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006549">
        <property type="entry name" value="HAD-SF_hydro_IIIA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004446">
        <property type="entry name" value="Heptose_bisP_phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006543">
        <property type="entry name" value="Histidinol-phos"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013954">
        <property type="entry name" value="PNK3P"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42891">
        <property type="entry name" value="PTHR42891"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08645">
        <property type="entry name" value="PNK3P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004682">
        <property type="entry name" value="GmhB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01662">
        <property type="entry name" value="HAD-SF-IIIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01656">
        <property type="entry name" value="Histidinol-ppas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="4 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <feature type="active site" description="Nucleophile" evidence="8">
        <location>
            <position position="10"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="8">
        <location>
            <position position="12"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="10"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="12"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="92"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="94"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="100"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="102"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="129"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="site" description="Stabilizes the phosphoryl group" evidence="9">
        <location>
            <position position="53"/>
        </location>
    </feature>
    <feature type="site" description="Contributes to substrate recognition" evidence="9">
        <location>
            <position position="103"/>
        </location>
    </feature>
    <feature type="site" description="Stabilizes the phosphoryl group" evidence="9">
        <location>
            <position position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00031828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR004682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR004682-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR004682-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR004682-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC93762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="184" mass="20013" checksum="D8C8C9FB1954DD31" modified="2018-07-18" version="1">MAQTKLIILDRDGVINHDSDEFIKSPQEWRPIDGSMEAIAQLNQAGYKVVVATNQSGISRKLFDMETLNAIHHKMHTAAQHAGATIDAVFFCPHAADFNCDCRKPKPGMIREIANRYDIELKGVPIVGDSLRDLQAGFIVGCAPHLVLTGKGEKTLAAGGLPPGAKVHLNLSTMVEHLLLNELV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1D7</accession>
    <name>A0A2S9H1D7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fimbrial protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1387</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93778">
        <property type="protein sequence ID" value="PRC93778"/>
        <property type="gene ID" value="S2091_1387"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009289">
        <property type="term" value="C:pilus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007155">
        <property type="term" value="P:cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1090">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000259">
        <property type="entry name" value="Adhesion_dom_fimbrial"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036937">
        <property type="entry name" value="Adhesion_dom_fimbrial_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008966">
        <property type="entry name" value="Adhesion_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00419">
        <property type="entry name" value="Fimbrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49401">
        <property type="entry name" value="SSF49401"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015573192" evidence="1">
        <location>
            <begin position="25"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="domain" description="Fimbrial" evidence="2">
        <location>
            <begin position="198"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="342" mass="35862" checksum="C61030A08D0A5F88" modified="2018-07-18" version="1">MIKLPAVLNFILCALAFSASTALAACTTETQSTFQMPFNLSVAQDAPIGTQIGPDIETGPFQLYNCSGTYSSQSLGVKAYGGSFNRMINGRRVYNTSISGVGFALGLRSIGNCDGSSAWIDGVNLGPEIHASWNRLVCTYPGFMPVQPIRGQFLLAFYKTGATNGGSLGSYAIGTGILRNNQNYWSTEATLTIKGLTVTTVSCSMPNITVPMGKTNTAQMFNGVGSRLSPVPFEIRLNNCVAGPNTSVKYQLDPLKPALDAKNGILALDSGGAKPAAAGVGIEIRSADGNEAVQEFGVPHAFGNITTGGSYSIPFNARYIQTAAKVAAGIANSAMTFTLIYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1D8</accession>
    <name>A0A2S9H1D8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1386</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93777">
        <property type="protein sequence ID" value="PRC93777"/>
        <property type="gene ID" value="S2091_1386"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="77" mass="8611" checksum="EACCE3006FD052BE" modified="2018-07-18" version="1">MQRKMTITIDEAVYAGLHKVIGRGNISQFLEGLARPYVLKEDTLDAGYQAMAADTKREAEAGEWCNALIQDVTHETR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1E3</accession>
    <name>A0A2S9H1E3_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Glycine--tRNA ligase beta subunit</fullName>
            <ecNumber evidence="10">6.1.1.14</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Glycyl-tRNA synthetase beta subunit</fullName>
            <shortName evidence="10">GlyRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">glyS</name>
        <name evidence="12" type="ORF">S2091_1372</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-tRNA(Gly)</text>
            <dbReference type="Rhea" id="RHEA:16013"/>
            <dbReference type="Rhea" id="RHEA-COMP:9664"/>
            <dbReference type="Rhea" id="RHEA-COMP:9683"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78522"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.14"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="4 10">Tetramer of two alpha and two beta subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.14" evidence="10"/>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93763">
        <property type="protein sequence ID" value="PRC93763"/>
        <property type="gene ID" value="S2091_1372"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004814">
        <property type="term" value="F:arginine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004820">
        <property type="term" value="F:glycine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006420">
        <property type="term" value="P:arginyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006426">
        <property type="term" value="P:glycyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00255">
        <property type="entry name" value="Gly_tRNA_synth_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008909">
        <property type="entry name" value="DALR_anticod-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015944">
        <property type="entry name" value="Gly-tRNA-synth_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006194">
        <property type="entry name" value="Gly-tRNA-synth_heterodimer"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30075">
        <property type="entry name" value="PTHR30075"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05746">
        <property type="entry name" value="DALR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02092">
        <property type="entry name" value="tRNA_synt_2f"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01045">
        <property type="entry name" value="TRNASYNTHGB"/>
    </dbReference>
    <dbReference type="SMART" id="SM00836">
        <property type="entry name" value="DALR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00211">
        <property type="entry name" value="glyS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50861">
        <property type="entry name" value="AA_TRNA_LIGASE_II_GLYAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 10 12" id="KW-0436">Ligase</keyword>
    <keyword evidence="6 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8 10" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DALR_1" evidence="11">
        <location>
            <begin position="590"/>
            <end position="692"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PRC93763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="694" mass="75772" checksum="D1B107F30EDFBFA0" modified="2018-07-18" version="1">MNQILLVELFTEELPPKALLKLGEAFAAGIVNSLKSRDFLEADSIATSYATPRRLAVSITKVRATSPDQQCREKVLPVSVALDANGNASAPLLKKLAAMGFADVQISQLERAPDGKAESFFYSHTAPGLTLQTGLQSALEESIAKLPVPKLMTYQRPDGTVVQFARPVHRLVALHGEQVVDVTLFGLNSGRTTQGHRFLSEGNITLAHADNYADDLLNKGKVIASFDQRKEKIRAELLAQAGADQVLMPESLLDEVNALVEWPVVYNCHFEEKFLSVPQECLILTMQTNQKYFALTDAAGKLRPRFLIVSNIATDTPQQIIRGNETVVRPRLSDAKFFFEQDQKKTLAERASGLANVIYHNKLGNQAQRVERVQALAAYIATQLSADVTLAKRAAQLAKADLLTDMVGEFPELQGIMGSYYARIDGEDAQVALAMTEHYQPRFAGDELPSSVTGTILALADKLETLVGIWGIGLQPTGDRDPFALRRHALGVLRMLIEKQLPLTLSGLLEQAVALFADNPAFTDPSVALTSFIYDRLRGILKERGFSPAEVEAVVAPQPDLLANIMLRLTAVQSFAALPESAALAAANKRITNILKKTEQVSFQVQTSLLQEDAERALFQATEDVSIKVQNAFAAGDFNNALQILATIRPQVDAFFNDVMVMAEDPALRANRIALLAMLHAILNQVADISKLAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1G8</accession>
    <name>A0A2S9H1G8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Thiopurine S-methyltransferase (TPMT)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_1416</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93807">
        <property type="protein sequence ID" value="PRC93807"/>
        <property type="gene ID" value="S2091_1416"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044995">
        <property type="entry name" value="TMT/HOL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008854">
        <property type="entry name" value="TPMT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32183">
        <property type="entry name" value="PTHR32183"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05724">
        <property type="entry name" value="TPMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51585">
        <property type="entry name" value="SAM_MT_TPMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC93807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="205" mass="23100" checksum="C1398BDC3D30CA1A" modified="2018-07-18" version="1">MSIPPIFVQRDATMPEFWNERFEQKFVPWDKGGVPLAVQQYIQHQTQPADTQCLIPGCGNGYEAAYLSECGWDVVAIDFSPAAVASARAAHPDWADRIVEADFFKYQPAKPLSLIYERAFLCALPPALRLDVAARWAELLPTRGLLMGFFYITDTGSKSGPPFSISQQELNTLLAPHFVCLEDKAVDDSIAVFENCERWQIWQKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1L1</accession>
    <name>A0A2S9H1L1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Hpt domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1449</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93840">
        <property type="protein sequence ID" value="PRC93840"/>
        <property type="gene ID" value="S2091_1449"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00088">
        <property type="entry name" value="HPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036641">
        <property type="entry name" value="HPT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008207">
        <property type="entry name" value="Sig_transdc_His_kin_Hpt_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01627">
        <property type="entry name" value="Hpt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47226">
        <property type="entry name" value="SSF47226"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50894">
        <property type="entry name" value="HPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HPt" evidence="2">
        <location>
            <begin position="20"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="modified residue" description="Phosphohistidine" evidence="1">
        <location>
            <position position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="131" mass="14685" checksum="A0E25C5B1B347490" modified="2018-07-18" version="1">MSDESKSKYNEQTAAQAQELAEAMRALGEGFIGRIPTMIAAMEKELNLISLDPQDPAPWKLLYRLLHSLAGSSGSFGFSELGDRASELEQRINEILKSDDIAALQGRLEFIRDQRKFMVWMSENHVKKIAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1R9</accession>
    <name>A0A2S9H1R9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Surface presentation of antigens (SPOA)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1528</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FliN/MopA/SpaO family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93919">
        <property type="protein sequence ID" value="PRC93919"/>
        <property type="gene ID" value="S2091_1528"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009425">
        <property type="term" value="C:bacterial-type flagellum basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003774">
        <property type="term" value="F:cytoskeletal motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071973">
        <property type="term" value="P:bacterial-type flagellum-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.330.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001543">
        <property type="entry name" value="FliN-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001172">
        <property type="entry name" value="FliN_T3SS_HrcQb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036429">
        <property type="entry name" value="SpoA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01052">
        <property type="entry name" value="FliMN_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00956">
        <property type="entry name" value="FLGMOTORFLIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101801">
        <property type="entry name" value="SSF101801"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FliMN_C" evidence="2">
        <location>
            <begin position="38"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="112" mass="12202" checksum="9CF54F6C4F6CEB67" modified="2018-07-18" version="1">MKNSETEIIQLNPQMIELSEIAPHHGKGPAIISDSLDAIEHVKVRLVVQVGEASITVGELHAMKEEHVIKLESLADAPVDILLEGRVVARGQLVAVDDNFGVRITELPKARL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1S3</accession>
    <name>A0A2S9H1S3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Flagellar biosynthesis pathway component FlhB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_1509</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the type III secretion exporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93900">
        <property type="protein sequence ID" value="PRC93900"/>
        <property type="gene ID" value="S2091_1509"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1690.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006135">
        <property type="entry name" value="T3SS_substrate_exporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029025">
        <property type="entry name" value="T3SS_substrate_exporter_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30531">
        <property type="entry name" value="PTHR30531"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01312">
        <property type="entry name" value="Bac_export_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00950">
        <property type="entry name" value="TYPE3IMSPROT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160544">
        <property type="entry name" value="SSF160544"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0966">Cell projection</keyword>
    <keyword evidence="4" id="KW-0969">Cilium</keyword>
    <keyword evidence="4" id="KW-0282">Flagellum</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="32"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="79"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="141"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="192"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC93900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="361" mass="40834" checksum="6EBC75ADE0F94E1F" modified="2018-07-18" version="1">MSEQEQDRSEAATPYKLKEAQHRGQVSKSQEATFAAILAAFVMVLYSVGPSIARQELRLTQQVFDHAARMDWSADTTGAWLFGVLSTALLYLMPLFLAIICAAILANMAQVGAIFSFKPVTPDFDRINPANGLKRIFSITLVYNAGKSLFKLFALTWVLWIVLEHAFPRLFTLGQINVRAHGSLVMGELPPMLFKLLLIILILALLDVGYTRWDYSKKMRMSRREVRDEGKQREGDPRIRARLRQIRAELLKQSRALRSLPDADVLITNPTHIAIALSYKHGEMPAPKMLAKGAGGLAKKMREIARLHNIPVVENRPLARAMYKRVKSGEYLPEDLYPMTAKILLWVYSLRKARARMESSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1U2</accession>
    <name>A0A2S9H1U2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Flagellar biosynthesis protein, FliO</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_1529</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93920">
        <property type="protein sequence ID" value="PRC93920"/>
        <property type="gene ID" value="S2091_1529"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044781">
        <property type="term" value="P:bacterial-type flagellum organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022781">
        <property type="entry name" value="Flagellar_biosynth_FliO"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04347">
        <property type="entry name" value="FliO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0966">Cell projection</keyword>
    <keyword evidence="7" id="KW-0969">Cilium</keyword>
    <keyword evidence="7" id="KW-0282">Flagellum</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015413449" evidence="6">
        <location>
            <begin position="28"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="51"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC93920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="149" mass="16308" checksum="FFE699D9204AAC3B" modified="2018-07-18" version="1">MNSLKRRSIAVAGLVAVIGMQVSSAYANAVTLPANIPFKSTTVADDNLVYRAIAAFLIAGAVAFGLAWCIKNFMPSFNKKMKRDKQLERLESMRLSTRSMLVRVRWGDEELLVGESEHGVTLIGKRPMESIIAAEATLPETTKVKGSHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1V0</accession>
    <name>A0A2S9H1V0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Outer membrane efflux protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1125</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC93952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93952">
        <property type="protein sequence ID" value="PRC93952"/>
        <property type="gene ID" value="S2091_1125"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015562">
        <property type="term" value="F:efflux transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003423">
        <property type="entry name" value="OMP_efflux"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02321">
        <property type="entry name" value="OEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="98" mass="10665" checksum="752BCA6EB72487C8" modified="2018-07-18" version="1">MPDAELQVAQNVWINYQGLKVSAENLRISLEIVESAQEAFDASESRYQKGVAAILEVITTQTALANAQQQRIQALAGWQNARIQLAASVGSLDLSTLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H226</accession>
    <name>A0A2S9H226_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">50S ribosomal protein L34</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpmH</name>
        <name evidence="6" type="ORF">S2091_1207</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the bacterial ribosomal protein bL34 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057289000.1">
        <property type="nucleotide sequence ID" value="NZ_PUGF01000004.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94034">
        <property type="protein sequence ID" value="PRC94034"/>
        <property type="gene ID" value="S2091_1207"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00391">
        <property type="entry name" value="Ribosomal_L34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000271">
        <property type="entry name" value="Ribosomal_L34"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020939">
        <property type="entry name" value="Ribosomal_L34_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14503">
        <property type="entry name" value="PTHR14503"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00468">
        <property type="entry name" value="Ribosomal_L34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01030">
        <property type="entry name" value="rpmH_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00784">
        <property type="entry name" value="RIBOSOMAL_L34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC94034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="44" mass="5122" checksum="BE3B524D3516720D" modified="2018-07-18" version="1">MKRTYQPSVVRRKRTHGFRARMATRGGRAVLNARRAKGRKRLAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2H4</accession>
    <name>A0A2S9H2H4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Sterol desaturase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1239</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94066">
        <property type="protein sequence ID" value="PRC94066"/>
        <property type="gene ID" value="S2091_1239"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008610">
        <property type="term" value="P:lipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006694">
        <property type="entry name" value="Fatty_acid_hydroxylase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04116">
        <property type="entry name" value="FA_hydroxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="72"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="135"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="domain" description="Fatty acid hydroxylase" evidence="2">
        <location>
            <begin position="76"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="241" mass="28887" checksum="CEF73DE065603024" modified="2018-07-18" version="1">MSLTIIFFVFAFCFVLERVIPGWHLPEVKTWPLRVLAINCVQLGVVLLAGISWERWLSAWSLFHLSNHVHPVAGGLIAYFIATFIFYWWHRWRHESNFLWVGFHQIHHSPQRIEVITSFYKHPIEMIVNSIIGSLLVYTFLGLSLEAGAFYTMLTALGEFFYHTSIRTPRWIGYFFQRPEMHRIHHQYQRHKNNYGDITWWDMLFGTYENPLEWKDHCGFDDEKEQQLIPMLLYKNVHRDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2K0</accession>
    <name>A0A2S9H2K0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acetyltransferase including N-acetylases of ribosomal protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1346</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94173">
        <property type="protein sequence ID" value="PRC94173"/>
        <property type="gene ID" value="S2091_1346"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="13"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="183" mass="21283" checksum="B8FE600AA25045D5" modified="2018-07-18" version="1">MSSIFPELQTPRIKLRELTEKDADVLFAMHSNYSIMQWYGTDHMTQREDALALITTFANLRKLPSPGIRWGLCTHESNTLLGTCGFHRWNKEWNSCTIRYDLKVEARGKGYMQEALRCAIVWAFANMNLNRIEAQIHPNNRASILLVEKLGFVREGLARKAGYWGEQYYDLCFYSLLKSEFYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H382</accession>
    <name>A0A2S9H382_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1063</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94442">
        <property type="protein sequence ID" value="PRC94442"/>
        <property type="gene ID" value="S2091_1063"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="53" mass="6200" checksum="D3E1F13D2A60A123" modified="2018-07-18" version="1">MESFSAIVKLLTIIRAAYNPMLFVRLLVRLFICSTQIETQHENKIHKNARRGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3E2</accession>
    <name>A0A2S9H3E2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0502</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94499">
        <property type="protein sequence ID" value="PRC94499"/>
        <property type="gene ID" value="S2091_0502"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="52" mass="6062" checksum="5A6E0D034E53D969" modified="2018-07-18" version="1">MQFCKMTDTALIFSIYSEVNSTLFIFRDVRALIIHSIQDKGMKLYLMLNVDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3L5</accession>
    <name>A0A2S9H3L5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative glutamine amidotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0563</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94560">
        <property type="protein sequence ID" value="PRC94560"/>
        <property type="gene ID" value="S2091_0563"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026869">
        <property type="entry name" value="EgtC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13230">
        <property type="entry name" value="GATase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="1">
        <location>
            <begin position="2"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="257" mass="28391" checksum="A54443568BFEBB2B" modified="2018-07-18" version="1">MCQLLGMNCNTPTDIVFSFTGFALRGGLTDEHQDGWGIAFFEGAGVRHLVDYQAAVRSPLAELIKAHPIKSKNVIAHIRKATQGKIALENCHPFIRECWGINWVFAHNGDLPGFMPTLNGTYLPVGTTDSERAFCFILQELRLRFGAQAPQLSELSAALQELCQEIAQFGTFNIMLSNGSALFVHCSTNLHYIIRQFPFNTAHLSDRDMSIDFAEVTTPKDRVAVIATAPLTNNETWAAFAPGEFKVFVDGTCHPES</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3M0</accession>
    <name>A0A2S9H3M0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ketosteroid isomerase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0587</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94584">
        <property type="protein sequence ID" value="PRC94584"/>
        <property type="gene ID" value="S2091_0587"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027843">
        <property type="entry name" value="DUF4440"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14534">
        <property type="entry name" value="DUF4440"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4440" evidence="1">
        <location>
            <begin position="3"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="125" mass="13885" checksum="1B70AF936E840480" modified="2018-07-18" version="1">MSIKSIIEAYGTALNANDIDSILSLYSADPVFMPQGAPALIGRDAVRAGYTFVFNTLKLNVQFTIHEIEEVGDLAWVRTSSAGRTRVLAAGIETDEGNNELFVFRKENGEWRIHRYLFATNLSKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3M6</accession>
    <name>A0A2S9H3M6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Metallo-beta-lactamase superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0588</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94585">
        <property type="protein sequence ID" value="PRC94585"/>
        <property type="gene ID" value="S2091_0588"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015460745" evidence="1">
        <location>
            <begin position="25"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="domain" description="Lactamase_B" evidence="2">
        <location>
            <begin position="69"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="338" mass="37803" checksum="2378D454FAAE6F3D" modified="2018-07-18" version="1">MKFSRILAAAAFAVALPFSCVSHAQEADNLPNFVSVLPQIKAKTLPVDPQKGYLVKEVRPGVYVITDGMYQSAFMTTGKGVILFDAPPSFGGHIISAVAEVTSEPIVELVYSHVHVDHIGSADLILKQFPHLKIVAEEGTAEFLREMKDPHRPMPNRIFKDHLSLKLGSATAELKVGHWHSPEGDLFIYLPGKKFLMAIDTLAAGSVPFMGFDLTMNMHDYMKVFDQILAYDFDVLVAGHLTYLADRNDVQVTKDYVTDVYTTVKRIHDTANQMDIMSKAAQKYTWDNKFAVFRTVLDEVTEQCAKEIQGRWINKLDGVDVFVTSHCSTALVYARWDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3T2</accession>
    <name>A0A2S9H3T2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0645</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94642">
        <property type="protein sequence ID" value="PRC94642"/>
        <property type="gene ID" value="S2091_0645"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="114" mass="13438" checksum="1EDD404E8AF8ECE8" modified="2018-07-18" version="1">MNLQTRLKNKLRTVLRIRTERVLPPPGPQPKIGSSIVRDRLRIRLKYPVTSEQWEWFTAHGWRTVDMRTNRREYASVSDKVLVKLLHMNGVERDVLHLRLVNKGSQENKANNVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3T7</accession>
    <name>A0A2S9H3T7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0596</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the BlaI transcriptional regulatory family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94593">
        <property type="protein sequence ID" value="PRC94593"/>
        <property type="gene ID" value="S2091_0596"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005650">
        <property type="entry name" value="BlaI_family"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34134">
        <property type="entry name" value="PTHR34134"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03965">
        <property type="entry name" value="Penicillinase_R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF019455">
        <property type="entry name" value="CopR_AtkY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="127" mass="14507" checksum="BEC268AC3AF0D513" modified="2018-07-18" version="1">MTDPHPTEGELAILRILWDRKKPSSVREVHEALLQTKDTAYTTVLKMLTIMNDKELVRRDETERSHRYTALYSEPVVQSSMLKSFVQNAFAGSAFKLVQRALDDDTASAEELDAIARLIAEAKKRRM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3V3</accession>
    <name>A0A2S9H3V3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0665</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94662">
        <property type="protein sequence ID" value="PRC94662"/>
        <property type="gene ID" value="S2091_0665"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022061">
        <property type="entry name" value="DUF3617"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12276">
        <property type="entry name" value="DUF3617"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015716032" evidence="1">
        <location>
            <begin position="19"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="190" mass="20308" checksum="DE1FA66BD776B2CE" modified="2018-07-18" version="1">MKKTTLAILLILSGIASAQTSSLKAGLWDMKQIKQVLDGQDMSAKMAAVQEKMQESMAKMTPEQRKKMEGMMNMGAGGTIRVCISPAMAARNAPIVDREGHCAPAKVTRSGNTSTFEFNCTNNGRTSVGSGKSTVNGDTVSTSVDMTVTDAKGHHSIQSESQMTFLGADCQGIKPADQMMKEMHGTTQQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3X6</accession>
    <name>A0A2S9H3X6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative gamma-carboxymuconolactone decarboxylase subunit-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0664</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94661">
        <property type="protein sequence ID" value="PRC94661"/>
        <property type="gene ID" value="S2091_0664"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051920">
        <property type="term" value="F:peroxiredoxin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029032">
        <property type="entry name" value="AhpD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003779">
        <property type="entry name" value="CMD-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02627">
        <property type="entry name" value="CMD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69118">
        <property type="entry name" value="SSF69118"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CMD" evidence="1">
        <location>
            <begin position="33"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="132" mass="14384" checksum="3704D328AC4DF9A3" modified="2018-07-18" version="1">MDNIRYLRGWEKLKEIDGEQGERVIASLSDIAPDFAKLLIEFPFGDIYSRPGLDLKSREIAVVAALTALGNAAPQLKVHIHGALNVGCSRTEVVEVIMQMAVYAGFPAALNGLFAAKEVFADRDAKKNAPEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3Z4</accession>
    <name>A0A2S9H3Z4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0693</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94690">
        <property type="protein sequence ID" value="PRC94690"/>
        <property type="gene ID" value="S2091_0693"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007433">
        <property type="entry name" value="DUF481"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04338">
        <property type="entry name" value="DUF481"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015709453" evidence="1">
        <location>
            <begin position="24"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="251" mass="27352" checksum="DF56485AB44B977E" modified="2018-07-18" version="1">MLLQTKNIAALVFGLSLCAFSHAEDPIKVTNKDYNLDADLNYLVNSTNSSTDVGNTKQNFSGHIDFKQISGDWAQEIKAAAVNSTDGNNPVDNTESYLVSGKTMHNEDASFYEFAKVQWEKDSSSAFKSQTALTLGLGKKLYSDDLQFLTAEVGAGAEYDVKQAPPNYSSTNGLGTLAAHYERKITTSVSFVQDVGYDYSSISKTIRSRSAISVMLTDKLSGLVSLDYKKIHSDLGDSRTILSAIGLKYSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3Z6</accession>
    <name>A0A2S9H3Z6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Response regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_0656</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94653">
        <property type="protein sequence ID" value="PRC94653"/>
        <property type="gene ID" value="S2091_0656"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="7"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="142"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC94653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="215" mass="24199" checksum="71177DACA215C41B" modified="2018-07-18" version="1">MLTETPYIAIIDDDPGVRGSLGMLLETKNWTFAEFERAGDFLENAKPSDFNCMIIDIRIPDMSGLELFEELKRRAKNTNDYLSPALFLSGHGDIPMVVKALKQGAADFLEKPVDHRTLLDAIARALSADRSARTSHNSQAKLIQEISELTLREREVLTEIVGGYLSKQIADHLNISTKTVEAHRLRICQKFNIRTSMELAAKLRDVSPSLWKKSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H423</accession>
    <name>A0A2S9H423_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Malonate decarboxylase acyl carrier protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_0723</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="3">Covalently binds the prosthetic group of malonate decarboxylase.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94720">
        <property type="protein sequence ID" value="PRC94720"/>
        <property type="gene ID" value="S2091_0723"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00710">
        <property type="entry name" value="Malonate_deCO2ase_dsu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023439">
        <property type="entry name" value="Mal_deCO2ase/Cit_lyase_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009662">
        <property type="entry name" value="Malonate_deCO2ase_dsu"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06857">
        <property type="entry name" value="ACP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03130">
        <property type="entry name" value="malonate_delta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="modified residue" description="O-(phosphoribosyl dephospho-coenzyme A)serine" evidence="3">
        <location>
            <position position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR609662-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC94720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="103" mass="11221" checksum="3B5DAEB308329698" modified="2018-07-18" version="1">MEKLNFEFDASTDGQTIQSQVMVGVVGSGDLEVLIEPDVALIRIQVTTSVDGMRSVWGALMHRLFSSGNLPAMSIELNDFGATPGVVRLRIEQALEELGLTHY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H426</accession>
    <name>A0A2S9H426_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="9">MotA/TolQ/ExbB proton channel family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_0686</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Membrane</location>
            <topology evidence="1 6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the exbB/tolQ family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94683">
        <property type="protein sequence ID" value="PRC94683"/>
        <property type="gene ID" value="S2091_0686"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002898">
        <property type="entry name" value="MotA_ExbB_proton_chnl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01618">
        <property type="entry name" value="MotA_ExbB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="106"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="149"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="domain" description="MotA_ExbB" evidence="8">
        <location>
            <begin position="79"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC94683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="217" mass="23831" checksum="D792B6CAD27325F6" modified="2018-07-18" version="1">MNMQLFHELAFYLMYACAALALFVIVERGIFYNYTLSQAIKLEKAMTHAVQNINELPAELTAKANLPLTLVSDILAEKHNLTNNKDLEDYSESVYIANRGEIQHRIWILDTIVTAAPLLGLLGTILGIIDTFKALAVSGVSDPGQVSQGIGTALYATALGIGIAVVGMFFFNMFQERIERINDHLKVLMLRACVGRLDSAHANTKPVSIETGKLHIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H439</accession>
    <name>A0A2S9H439_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Malonate decarboxylase, beta subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0724</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94721">
        <property type="protein sequence ID" value="PRC94721"/>
        <property type="gene ID" value="S2091_0724"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016831">
        <property type="term" value="F:carboxy-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044262">
        <property type="term" value="P:cellular carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034733">
        <property type="entry name" value="AcCoA_carboxyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011762">
        <property type="entry name" value="COA_CT_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017556">
        <property type="entry name" value="Malonate_beta"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01039">
        <property type="entry name" value="Carboxyl_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03133">
        <property type="entry name" value="malonate_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50980">
        <property type="entry name" value="COA_CT_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CoA carboxyltransferase N-terminal" evidence="1">
        <location>
            <begin position="1"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="287" mass="30508" checksum="2293EDCF11CA74B8" modified="2018-07-18" version="1">MDTHHSIDIDTLLKQKSFIELTARDRARALLDQGSMRELIGPFDRVKSPWLEQQGVVTQSDDGVIVAKGTFNLQPCVLLAIEGAFQGGSLGEVGGAKIAGALELAANDNRNGIPTVAIILFETGGVRLQEANLGLAAIAEIHSAIVDLRSYQPVIGISAGTVGCFGGMSIAAALCSYLIVTREARIGLNGPGVIEQEAGIAEYDARDRPFIWSFTGGQQRVDSHLADSLVEDDVAGIRDNVGRLLALGVPKVHRSQQIAHFIRALDLVDAQTQATPEMARQIYASGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4A6</accession>
    <name>A0A2S9H4A6_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF4124 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_0719</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94716">
        <property type="protein sequence ID" value="PRC94716"/>
        <property type="gene ID" value="S2091_0719"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025392">
        <property type="entry name" value="DUF4124"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13511">
        <property type="entry name" value="DUF4124"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015741919" description="DUF4124 domain-containing protein" evidence="2">
        <location>
            <begin position="28"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4124" evidence="3">
        <location>
            <begin position="16"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="55"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC94716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="156" mass="16719" checksum="BDE7F76A5CBF93B6" modified="2018-07-18" version="1">MNQNPFHRFSQFLGAALLLLSPMLCSAQVYKCTENGSVTFQSDPCKTGGKLMHIDSGPSAQAINEAKNRADKDKKSAWDKSASPTTSRNDAPEAHPPDCEKLNKAVADAEAQRKELIAPGIGSPTSAGIRNVNRLSGPVDQQYNYAKNMADASGCH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4F1</accession>
    <name>A0A2S9H4F1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0057</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94862">
        <property type="protein sequence ID" value="PRC94862"/>
        <property type="gene ID" value="S2091_0057"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.690">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045372">
        <property type="entry name" value="YidB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027405">
        <property type="entry name" value="YidB-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20159">
        <property type="entry name" value="YidB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140804">
        <property type="entry name" value="SSF140804"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="138" mass="14067" checksum="F330111E5909BDE3" modified="2018-07-18" version="1">MGLLDAALGMLSGNNATDPKMAVMQAAIGLLSNHEGGASAGVQELMSTLQNAGLSEHVASWIGEGQNLPVSGEQIQQALEPSGVLQQLAETAGLSHEEVASHLAAMLPGVIEKFSQNDGQIGGLGNIAGMLSQFMSSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4X2</accession>
    <name>A0A2S9H4X2_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Porin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0121</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell outer membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the OprB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94926">
        <property type="protein sequence ID" value="PRC94926"/>
        <property type="gene ID" value="S2091_0121"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046930">
        <property type="term" value="C:pore complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015288">
        <property type="term" value="F:porin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008643">
        <property type="term" value="P:carbohydrate transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006811">
        <property type="term" value="P:ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007049">
        <property type="entry name" value="Carb-sel_porin_OprB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038673">
        <property type="entry name" value="OprB_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04966">
        <property type="entry name" value="OprB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="2" id="KW-0406">Ion transport</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0626">Porin</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU363072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="509" mass="55354" checksum="117AC92DACCB90A1" modified="2018-07-18" version="1">MFTRPHRSNSLIANTRFKQTPLARLLACIGGIASLAVLVTPEAAYSAPPPISIAAGPSDGSTPQSSGFFGFMDGIDRSSNLLGDMWGLRTDLSKYGMTLSVQETSESLGNVTGGTQKGFNYDGLTQAVLQLNTQRAFGLYGGLLNISALQIHGQNVSANNLQTLQTASGIEADRGFRLWEMWYDQKFLDEDRLDVKIGQQSVDQEFIVSSNALMFVNTMFGWPMLPSADMPGGGPAYPLSALGARISARPVNGLTILAGVFNGSPVGNKPGDPEQQNQHGVNFPLGNGTLSMVELQFAYPALGSMVQADETPPLGWTYRVGAWYNSEMFNDQRFDQNGLSLSNPNSNQVAAQHHGNFSYYAVADHLIWRDATELNRTVALFARVMATPLTDRNLVDGSLNAGIVLHCPFAYRTDDTLGFGVGYAHVSKQASALDRDTNYYSSTNMPVRSGEKFAELTYQYQVKPWLQLQPDIQYVVNPGGGVTNPDNPNNPSQRIKNELVLGLRTNIAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H551</accession>
    <name>A0A2S9H551_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 15 16">Protoporphyrinogen IX oxidase</fullName>
            <shortName evidence="15">PPO</shortName>
            <ecNumber evidence="15 16">1.3.99.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">S2091_0293</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15 16">Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 15 16">
            <text>3 A + protoporphyrinogen IX = 3 AH2 + protoporphyrin IX</text>
            <dbReference type="Rhea" id="RHEA:62000"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:57306"/>
            <dbReference type="ChEBI" id="CHEBI:57307"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15 16">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
        <text evidence="15 16">Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4 15 16">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; protoporphyrin-IX from protoporphyrinogen-IX: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="15">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 15">Cell membrane</location>
            <topology evidence="3 15">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 15 16">Belongs to the HemJ family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.99.-" evidence="15 16"/>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95098">
        <property type="protein sequence ID" value="PRC95098"/>
        <property type="gene ID" value="S2091_0293"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00251">
        <property type="reaction ID" value="UER00324"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070818">
        <property type="term" value="F:protoporphyrinogen oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006782">
        <property type="term" value="P:protoporphyrinogen IX biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02239">
        <property type="entry name" value="HemJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005265">
        <property type="entry name" value="HemJ-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40255">
        <property type="entry name" value="PTHR40255"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03653">
        <property type="entry name" value="UPF0093"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004638">
        <property type="entry name" value="UCP004638"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 15 16" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 15 16" id="KW-0349">Heme</keyword>
    <keyword evidence="13 15 16" id="KW-0408">Iron</keyword>
    <keyword evidence="14 15 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="10 15 16" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12 15" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 15" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="48"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="82"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="115"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="15">
        <location>
            <position position="8"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="15">
        <location>
            <position position="84"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00006501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00017504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRNR" id="PIRNR004638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="PRC95098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="140" mass="16115" checksum="3A105A56AC2FB139" modified="2018-07-18" version="1">MLWIKALHIVFVMSWFAGLFYLPRIFVNLAEEGPGMATERLLKMARKLYRFTLMLSALALIFGLVLYLWYGIGRGPGNGWMHAKLGLVVLILGYQHACGSLLKKFEHGINKRSHVWYRYFNEIPVVMLLIVVCLVVVKPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H570</accession>
    <name>A0A2S9H570_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0276</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95081">
        <property type="protein sequence ID" value="PRC95081"/>
        <property type="gene ID" value="S2091_0276"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC95081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="298" mass="33008" checksum="7B136DE0C5D7CD3A" modified="2018-07-18" version="1">MLDDLALFILIVETGSLNAAARKAGLPASNLTRRLQKLEQELGYRLVHRSARRLTVSEEGWQYYEQCRPLLQALQQATQQLGDTFNQVAGRITVLAPVNLANGILAPAWINFMTQYPEIQLELQLSNHTQDILDHSAALAIRTGPQPDSSLNQHILGTTQVLLVAASAYLAKHGNPSTPEELEQHELLVAEPLSNWIVHHQTSGQRLQWSPQARFRVNDIALAVTAAEAGLGIVFCPLTLCDAGLKAGRLVEVLADWRVAPRSLYAVWPQRQVPARVRVLIDYLVQFCQGNELLGARL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H580</accession>
    <name>A0A2S9H580_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">LysR substrate binding domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0221</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95026">
        <property type="protein sequence ID" value="PRC95026"/>
        <property type="gene ID" value="S2091_0221"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08417">
        <property type="entry name" value="PBP2_Nitroaromatics_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037402">
        <property type="entry name" value="YidZ_PBP2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="6"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC95026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="302" mass="33900" checksum="7452AA1B2B0F5A96" modified="2018-07-18" version="1">MHISRIDLNLFVVFEAIYSEGSITRAAKTMNLSQPALSHALGRLRELLNDPLFQRLGSNMVPTPLAHSLIGQIRTALQTLDVSVNNSRRFDPLLSSRQFTLGFRDVLESTALPKLINALQTSAPQVELASVKVERSELESELMAGSLDLAVDVLLPFPAPIRRRLISRDSMVVVARNNHPGIKKKLTLANYLKQNHVLVSSRRTGPGLEDLELSRQGHQRHIGLRCQHYFAASLVVSESDLLLTMPGKYAQLANKHLDNQIWPLPLKMPPFDVYLYWHENAENDPANCWLRELVMQCFGGIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5H2</accession>
    <name>A0A2S9H5H2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Polysaccharide deacetylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_0412</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95217">
        <property type="protein sequence ID" value="PRC95217"/>
        <property type="gene ID" value="S2091_0412"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002509">
        <property type="entry name" value="NODB_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01522">
        <property type="entry name" value="Polysacc_deac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="SSF88713"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51677">
        <property type="entry name" value="NODB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015779072" evidence="2">
        <location>
            <begin position="33"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="domain" description="NodB homology" evidence="3">
        <location>
            <begin position="244"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="454"/>
            <end position="477"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC95217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="477" mass="52851" checksum="32C9D58CAC05DCBB" modified="2018-07-18" version="1">MFALISTSTTKKWLAGLVCGAYLTLLCTAPHAQNSQPPASMSTDVQTLINNYRRILALQELSISANAATPKHQEAVRIGEYLFIENQHLSTSITERLLVHPQHGTQTDIDDFLTALNNPALQDADLFAVRSIVTEVAKKGQLSSAQGKQIRAVLKNLAIAHNKYGQELSVVLSQKTITQSKPERPAWAAYIAEIEKEYPPNTVLEELGHAIPNQEQQATPSDKTAELVAQTRANEWQGLQLEKGTVLLTFDDGPHPVYTKEILEILARYKVKAIFFQLGQNLGTVTDGHAELTRNEEVEKEILNAGHAIANHSFTHPFLPKLDQAQVQQEIDKTQALLDLIIPEDAHRTHMFRAPYGARNSMILGEIGERGLRSVLWNVDSLDWSDPVPESIVHRILQELEHAGRGIILMHDIHPKTVIALPMLLDELIKRGYHFVQWDGEKLVATVRENPATSAPVANPATAIPMSSESNNSGKNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5J5</accession>
    <name>A0A2S9H5J5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative nucleoside-diphosphate sugar epimerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_0455</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the polysaccharide synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95260">
        <property type="protein sequence ID" value="PRC95260"/>
        <property type="gene ID" value="S2091_0455"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05237">
        <property type="entry name" value="UDP_invert_4-6DH_SDR_e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003869">
        <property type="entry name" value="Polysac_CapD-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02719">
        <property type="entry name" value="Polysacc_synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="14"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="46"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="79"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="105"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="Polysacc_synt_2" evidence="3">
        <location>
            <begin position="282"/>
            <end position="585"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC95260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="656" mass="72809" checksum="D2C88979C1A6E6A4" modified="2018-07-18" version="1">MTRFLSLTRFQKQCIAVSADLFFLPFMFLTALWMRFDVVDYLLIKQFGVLIIAAPLIAIPIFIRLGLYRAVIRFVDQKIVFVVVYGVTLTVFVLLALAVFLHVGILSRAVFGIFGISAVMYMLASRFMARAYLLQLSNNDNAIRVAIYGAGHTGAHIATAFNASHDYIPMFLIDDKKELQGATIAGIRVYPSTDLPELIAKNRVQEIHLVMPSTPKKTQSVILNRLEKLRVKVRITPPIRDLLNGELTVKDLREIEIEDLLGRDSVEPNHALIAACIADKIVLVSGAGGSIGSELCRQILLQKPTRLILLDTSEFALYTIEKELASLKTSHALSTQIMPFLVSVLETEKCQQILSTFNVQTVYHAAAFKHVPLVEQNPIEGIRNNVFGTLSIAKASMHAGVANFVLISTDKAVRPTNVMGATKRLAELVLQGLSAQKTVDQIAVTQKSNTRFCMVRFGNVLGSSGSVVPLFRQQIMAGGPITLTHPDITRYFMTIPEAAQLVLQAGSMGAGGDVFVLDMGEPVKILDLAERMVHLSGLSLTSESSESNAIEIQHVGLRPGEKLFEELLIGDNVDGTEHPLIMRAEESMIAWPVLQVLLDKLDIACRNFAYEKVRELLLEAVKEYQPQCGIEDMIWHEEKKRPLYENGKHVNDRKLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5K7</accession>
    <name>A0A2S9H5K7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Methyltransferase domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0465</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95270">
        <property type="protein sequence ID" value="PRC95270"/>
        <property type="gene ID" value="S2091_0465"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025714">
        <property type="entry name" value="Methyltranfer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13679">
        <property type="entry name" value="Methyltransf_32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltranfer_dom" evidence="2">
        <location>
            <begin position="51"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC95270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="293" mass="32759" checksum="A72BF193C2FEF404" modified="2018-07-18" version="1">MKKNNSTKNSTDTSSAAEGLAHEIRPGQSIELLKELHILTRDGKMNQDSRRKLKQVYHLYQFIEPLMQAVQLDHADVSLVDHGAGKSYLGFILYDLYFKSQQNQSRIYGIETRDELVSKSQALATRLGFAGMSFLNLSVAQSITSDALPAKIDIVTALHACNTATDDAIAFALKKQASYIVLVPCCQAEVAATLKKSKNAAIKNNPLSELWRHPIHTREFGSQLTNVLRCLQLEAHGYQVTVTELVGWEHSMKNELIVATYKNLPRQHAQERLTQVLHSTGLEALQERFFTAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GS76</accession>
    <name>A0A2S9GS76_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4721</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000054">
        <property type="protein sequence ID" value="PRC90569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90569">
        <property type="protein sequence ID" value="PRC90569"/>
        <property type="gene ID" value="S2091_4721"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC90569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="140" mass="15804" checksum="F5EBA01102A66184" modified="2018-07-18" version="1">MILQIFRVLFIAMTFDWSVSAYSADLKGEWALQVEDQKHQPIAVLSIKFTNRKADSCLSDNWLRVEVLSATTKDDGFFPISDRLSYKIENNKLTIGRNEICDAYLGLGGSISSEEIHGDYYSLGMAGTRALGFFSLRKKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GS84</accession>
    <name>A0A2S9GS84_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4722</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000054">
        <property type="protein sequence ID" value="PRC90570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90570">
        <property type="protein sequence ID" value="PRC90570"/>
        <property type="gene ID" value="S2091_4722"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC90570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="192" mass="21766" checksum="BADBC958569F256E" modified="2018-07-18" version="1">MFSPAPNARGSLKPGTLYAIAGEHDWIYYGQVDQGKKVGFFRFRSKQLVSNEEILTNTVMSRVNVVYSSIGSALRKGSWKLLGIGAIHKELLHSLSVVQWPVGTLIVTIWMDGKEIGETRVEDPKIQDFEIIAGWDAFHHIPGRLRVDFEGDDSNIMIGGPIRRERRLKEEAARRAPNMPYHQLLPDWVPCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSI6</accession>
    <name>A0A2S9GSI6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4639</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000040">
        <property type="protein sequence ID" value="PRC90656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90656">
        <property type="protein sequence ID" value="PRC90656"/>
        <property type="gene ID" value="S2091_4639"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC90656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="251" mass="27769" checksum="8F7ACA5A6FCCC458" modified="2018-07-18" version="1">MIIPQRGSNAFKLLYTGNNGEEIGLDEVQLLDDYPQTRIRDLSALLNDSNLFIRYQAILILTAWGLEVGIDNAENMIVAGVADDLNLSPNRINGKDNRFDDLAEAIHLYVLSGGSGVRACKAFCALLKSYPIYYFESKFKRALLKHATPEMIGEIKDSILKCLKAGKFYQASQLLPILAKLDSVACWDIFPEIAALPMQIPDPAANIAEALRYISTQDSDKLLTQYLTHKGAGVALAAQESIDFKKKQSIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSM3</accession>
    <name>A0A2S9GSM3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_4543</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000037">
        <property type="protein sequence ID" value="PRC90717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90717">
        <property type="protein sequence ID" value="PRC90717"/>
        <property type="gene ID" value="S2091_4543"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015562">
        <property type="term" value="F:efflux transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003423">
        <property type="entry name" value="OMP_efflux"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010131">
        <property type="entry name" value="RND_efflux_OM_lipoprot_NodT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02321">
        <property type="entry name" value="OEP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01845">
        <property type="entry name" value="outer_NodT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0564">Palmitate</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1134">Transmembrane beta strand</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015368922" evidence="2">
        <location>
            <begin position="28"/>
            <end position="492"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU362097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC90717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="492" mass="52675" checksum="77624A7FB7B14CA2" modified="2018-07-18" version="1">MKSYKFSKHIAPSLAPLLAALLLTACAAPEFKQPQMDSPLSFKESSQPLTAADGTQWQLAHPAEIQQRGQWWLVFNDPALNQLIADATSANANLAVAAARVKQARAIAGIAEADRIPQVGLLAGGQRERASPLSLNLPQGTAVSPANIYQANLSASYEIDLFGRVASEVNAARADAAASEATYRSVLLSLQADVAQTYFKLRETDAELDTLNQTVKLREESVHVNQRRYDLGDLGEFDLTRAKTELLTARAEAIGLQRQRVTNEHALAVLLGKPASEFTAEVHPLEEYVQLPLIPAGLPSALLERRPDIVSAQRVMEASNARTGVAKAAMFPALNLNAGVGGLANTMPDVFKWTNGSWLLGALLSMPVIDGGRNKAAVTRSEAVSEESVATYRQSVLVAFAEVEDNLAGLRILAGQAEQIDAAVLSARRSAELAQKLYAAGRSSYLDLLDAQRNLATVERNAVQLRGSRAVTTVALIRALGGGWDNTVGVTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSN3</accession>
    <name>A0A2S9GSN3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Esterase/lipase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4546</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000037">
        <property type="protein sequence ID" value="PRC90720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90720">
        <property type="protein sequence ID" value="PRC90720"/>
        <property type="gene ID" value="S2091_4546"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Abhydrolase_3" evidence="1">
        <location>
            <begin position="47"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="294" mass="31111" checksum="019189D42092EF6E" modified="2018-07-18" version="1">MSEIIERGIAQPHQLKVRDTKVQGAEGSLAARIYSCVPVGSKQDSLIVFFHGGGFDTGDLNDADEFLNHLAMGNPDQLVLASSYTLATQKPFPAAVEDAYAVLTWVKKNKVRLGWSGKQLIVAGIEAGANLAAVCTLMARDRGGPDINGQILIMPMLDPGLTTCSMRAMPAPELVNVADACAAAYRGYLPNAADRIHPYASPLQSSRLKNLPPALILSAEDDPLRDEAEQYGTKLINAGVNTTVHRLPPAPLQEAGARNECACRGHALGAIGVFLGGLQQQQAEKSTSGTTSPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GST3</accession>
    <name>A0A2S9GST3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Flagellar biosynthesis/type III secretory pathway protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_4527</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000036">
        <property type="protein sequence ID" value="PRC90779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90779">
        <property type="protein sequence ID" value="PRC90779"/>
        <property type="gene ID" value="S2091_4527"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018035">
        <property type="entry name" value="Flagellar_FliH/T3SS_HrpE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02108">
        <property type="entry name" value="FliH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0966">Cell projection</keyword>
    <keyword evidence="3" id="KW-0969">Cilium</keyword>
    <keyword evidence="3" id="KW-0282">Flagellum</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="FliH" evidence="2">
        <location>
            <begin position="84"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC90779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="229" mass="25550" checksum="7DFEFB7955C6534F" modified="2018-07-18" version="1">MRLSDVIAKGKLSAYQRWEMTSFEENTPENKKPGTDKAVVQITESNQKELDDLKVSAQKEGFAKGFEEGHQVGLKTGQQEEQQELVAFKQISTQFNASLQQAEHLVAQEVLDLALDIAKAMLKNALTINPELIIPIIEQAIASLPSVQQPAQLFLNPKDAILVQAKIGAELSEAGWVIVPDAHLKIGDCRIETMKNQINASLSSRWQQIAEALGRENSWYVVDHTEHRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GST6</accession>
    <name>A0A2S9GST6_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Flagellar motor switch protein FliM</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">S2091_4532</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Bacterial flagellum basal body</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Cell inner membrane</location>
            <topology evidence="3">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the FliM family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000036">
        <property type="protein sequence ID" value="PRC90784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90784">
        <property type="protein sequence ID" value="PRC90784"/>
        <property type="gene ID" value="S2091_4532"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009425">
        <property type="term" value="C:bacterial-type flagellum basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003774">
        <property type="term" value="F:cytoskeletal motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071973">
        <property type="term" value="P:bacterial-type flagellum-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17908">
        <property type="entry name" value="FliM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.330.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028976">
        <property type="entry name" value="CheC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001689">
        <property type="entry name" value="Flag_FliM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001543">
        <property type="entry name" value="FliN-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036429">
        <property type="entry name" value="SpoA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02154">
        <property type="entry name" value="FliM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01052">
        <property type="entry name" value="FliMN_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002888">
        <property type="entry name" value="FliM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00955">
        <property type="entry name" value="FLGMOTORFLIM"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101801">
        <property type="entry name" value="SSF101801"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103039">
        <property type="entry name" value="SSF103039"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01397">
        <property type="entry name" value="fliM_switch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0975">Bacterial flagellum</keyword>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="13" id="KW-0966">Cell projection</keyword>
    <keyword evidence="7" id="KW-0145">Chemotaxis</keyword>
    <keyword evidence="13" id="KW-0969">Cilium</keyword>
    <keyword evidence="8" id="KW-0283">Flagellar rotation</keyword>
    <keyword evidence="13" id="KW-0282">Flagellum</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FliMN_C" evidence="12">
        <location>
            <begin position="250"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00021898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00025044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PRC90784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="341" mass="38358" checksum="AB80E511D9CF3601" modified="2018-07-18" version="1">MSDNFLSQEEVDALLKGVTGDQDDADTQEDTGSVRTYNLATQERIVRGRMPTLEIINERFARLLRIGLFNFLRRSAEVSVGTVRVSKYSEFIRNLVVPTNLNLIHMKPLRGTALIVMDPNLVFLLVDNLFGGDGRFHTRVEGRDFTQTEQRIILRILDIIFETYAKSWNPVYPVEFEYIRSEMNTQFANIATPNEVVVCTTFTIELGPVSGEMHFCMPYSMIEPIRDTLTSSLQGETLEVDKRWVRLMTQQIQIAEVELVADLGTANMNLGAILNLRVGDIIPLTVPETLSAKVDGTPVMECKYGIFNAQYALKVEKLLSSSAQEMAVEAQVESKQGARHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSY7</accession>
    <name>A0A2S9GSY7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4490</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000035">
        <property type="protein sequence ID" value="PRC90827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90827">
        <property type="protein sequence ID" value="PRC90827"/>
        <property type="gene ID" value="S2091_4490"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="96"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="122" mass="13984" checksum="FB25A2297D6D7D5D" modified="2018-07-18" version="1">MIQSKRALITVFFLFLIDVCLSGYFRLRHSEMEGLVSTVCNIGVGIAVYCWYYSDSEVYKYERSGVLNFCMIFLTIFAMPYYLIRSRPTGQKGKALLKCIGFCAAVLLISIIMEIFMTILIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GT97</accession>
    <name>A0A2S9GT97_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Acyl carrier protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_4341</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000032">
        <property type="protein sequence ID" value="PRC90940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90940">
        <property type="protein sequence ID" value="PRC90940"/>
        <property type="gene ID" value="S2091_4341"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="2">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="1">
        <location>
            <position position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC90940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="81" mass="8546" checksum="430B6FD16A21471F" modified="2018-07-18" version="1">MSSIIALKNILTETLHLGAQAQKLQADSMLLGSLAELDSMAVINVIVAIEEHFGITVEDDEISGNTFATLGSLAAFVDSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTH0</accession>
    <name>A0A2S9GTH0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Neisseria PilC beta-propeller domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_4318</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000031">
        <property type="protein sequence ID" value="PRC91022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91022">
        <property type="protein sequence ID" value="PRC91022"/>
        <property type="gene ID" value="S2091_4318"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008707">
        <property type="entry name" value="PilC_beta_prop_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05567">
        <property type="entry name" value="Neisseria_PilC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015398670" evidence="2">
        <location>
            <begin position="25"/>
            <end position="1282"/>
        </location>
    </feature>
    <feature type="domain" description="Neisseria_PilC" evidence="3">
        <location>
            <begin position="663"/>
            <end position="1076"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="105"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1251"/>
            <end position="1282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="112"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC91022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="1282" mass="130130" checksum="F0D3FD6970630E4C" modified="2018-07-18" version="1">MDKRSIGLLCASSLASLLPLYAFAQLTVTENFNTGSTNQTWTTTGGACLTAGTYVAPSGSTPAANVTPAGTIPGCATSGGASDSYYLNLGSKLIGGNTGNALPDPSGRGALRLTNGDTTTGSNGNNETGAIISTSAFPSSEGLQITFNTVTYGGNGYNNGATNSGADGMEFFLADASVTTQITTTSTSTSGVTTTLTSYPLTIGSFGGSLGYDCSSSKGGGMAGGYIGLGIDEFGNFANNTDNGSLTDANAFNVRSPNTVSLRGAGNITAAMINSLNYNSAATTSAPTSTTSLSYSYTPVVTVTGSGRNRTTSTSTTTSTSTTVLTSTSSTSTNYATNAILTSLCAKPTYTLTATPITVTTVTKTVNGGTPSTLTPSTTSATSTTTTTTVMDYPMLAHNVLPSANLIYSQEAISNASRTSGTPISYTLTLTKTGLLSLSYSYNQGVYVPVISNQSITGSGTGSSAVNNGPIPANFLYGFTAGTGGGSNVHEITCFKAAQITESSSSAAGNVPQANKVENNEGSQIYLASYNPTFWTGSLTATPLTVLTNGNIVIGVPSSNGLINTNATWDASCKLTGTANNLPNPVCATTGGTNTPEAPTARAIATWNGSAGIAFTGANLAGSTALNAGDPSNNQLGSARVDYLRGVRTNEANNTFRTRYSVLGDIINSSPVSVGGPSSSFTQSWKDLLYPSATAPEGSTSYATFASNNAGRLNVVYIGANDGMLHGFEAGQSTSSSTGGVTTTTFNSTNNDGLEIMAYVPSLALSTIHSTTNSLDYSGLTYAHNAFVDATPGTGDLFYGGAWHTWLVGGLGDGGNAGGIIAGPTVTAAGNVFALDITSPSSSLTDASVASLVMGDWTNSNITCVGNPTCGKNMGGIYGTPIIRRLHDGNWAAIFGNGLNSSSGTAGIFVMEIAQANGAVSFYYIDTGTSASSDPTGKNTKNGIAYVTAADLDGDHITDYVYAGDALGNVWRFDLTSNNATTWTSATPFKLFTASTASALQPISTAVTASVINTNNTNRIMIDFGTGQQLPQTLSSAATYATQTQNLYGIWDWNLGTWNNNSAVQYLTGTNLSITTSTLTQQVLSSVTLSNPTANTSGSTKAYTATNNLVCWPGAANCAPTTNATPNPSYGWQLSLPNSTEQIIYNPTVYSSIFWVNSIIPAQADAFACTITAASGYSYGISIATGGATAGIFNSAIGNTNTTDANVVGLSLNGVGTVQLMQSTGTVTSAAGVTTTVNVTTLGTALAGGGGKTVVVNPPPPNPGGGSGNGSPTGRISWLEIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTH1</accession>
    <name>A0A2S9GTH1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4306</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000031">
        <property type="protein sequence ID" value="PRC91010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91010">
        <property type="protein sequence ID" value="PRC91010"/>
        <property type="gene ID" value="S2091_4306"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="82" mass="9372" checksum="288525664C7865B3" modified="2018-07-18" version="1">MDEINTLESLGFTLPTPAYLFGAILFGIIGYVAYRFGKKTTNNYIKWLGVVLMFYPYAVPSTWMLYVVGIGLCGACYYYRDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTR0</accession>
    <name>A0A2S9GTR0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4185</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000029">
        <property type="protein sequence ID" value="PRC91089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91089">
        <property type="protein sequence ID" value="PRC91089"/>
        <property type="gene ID" value="S2091_4185"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="309"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="419"/>
            <end position="453"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="1128" mass="129292" checksum="312087A2C5A7F86E" modified="2018-07-18" version="1">MNSPTEASLPLDFSNEPALSGFRLQRLEVFNWGTFDERVWTLNLNGKNALLTGDIGSGKSTLVDAVTTLLVPAHRIAYNKAAGADHKERSLRSYVLGHYKSERNDISGTAKPVALRDQHNYSVILGVFHNIDYNQTITLAQVFWMKEAQGQPARFFVGAERDLSIAKDFAEFGTEITALRKKLRGPGINLFDSFPPYGAWFRRRFGIENEQALELFHQTVSMKSVGNLTDFVRNHMLEAFDVAPRIDALIGHFDDLNRAHAAVLKAKRQVELLTPLMSDGTRYTEQQTQVAQLRSCRVALEPYFAGLKLDLLDKRIAALRQEFEQQTHQIARSEEVRDRLKVEENELERDIHQNGGDRIQKLTLEIEAKQQERNTRQIKASRYTKLLSDISEKPCLNEADFLVRRNNLPIDAQTTSAQIEKLQNTIAGHSLNLLQLEQEHALLTTEITSLKARRNNLPAEQITMRSALCQALNLPEEDMPFSGELLQIHDNERDWEGAAERILRPFGLSLLVPDMHYQLVADWVDKIHLKGRLVYFRIRQNSSVSTALPSLHRDSLARKIAIKPDSEFFDWLERELVRRFDVACCATQDQFRREVRAVTPNGQIKMPGERHEKDDRHRINDRSRYVLGWSNLDKIATLEASAAKLDVEKNKLRDVINKTQAVLDTLNIKLATLSRLDEYRDFNEINWQAVAVLIAQLQDEKKLLESASDILLQLTQRLTKVRSELLDVKIKIDLQIEKRGGTGVKRNVAEELHRHTTLILNQQELAVHTAYFDALNSIRNEALGEHNLSVESCDARERDLRGWLQTKIESEDGKLNRLRDKIVKAMTSYNNEFRLETEEVDASIDAVFEYDTMLAKLAADDLPRFEARFKELLNEDTIREVANFQSQLGREQINIKDRITRINASLTGIDYNPGRFIELEAKPSMDTDIRDFQAELRACTEGTLTGSEDDHYSEAKFLQVKYIIERLRGRESLSELDRRWSNKVTDVRNWYSFAASERWRDDGREHEHYSDSGGKSGGQKEKLAYTVLAASLAYQFGLEWQATRSRSFHFVVIDEAFGRGSDESAQYGLRLFAQLNLQLLIITPLQKIHIIEPFVSNVGFVHNEQGRTSKLRNLSIDEYRTEKTKVLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTX9</accession>
    <name>A0A2S9GTX9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4162</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000028">
        <property type="protein sequence ID" value="PRC91161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91161">
        <property type="protein sequence ID" value="PRC91161"/>
        <property type="gene ID" value="S2091_4162"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="95" mass="11126" checksum="852B24DD1B5FD772" modified="2018-07-18" version="1">MAGTGFRYLPFRWTLPLRMLLWPLTKLRAPFSGLMRELMKIPYLWQKPLRLENSKLLHLLGREPYTPLDEAMRLTLIGLGCVGHQRLTCNTYVVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTZ0</accession>
    <name>A0A2S9GTZ0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4092</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000027">
        <property type="protein sequence ID" value="PRC91197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91197">
        <property type="protein sequence ID" value="PRC91197"/>
        <property type="gene ID" value="S2091_4092"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="45" mass="5041" checksum="5CF162FF53115A40" modified="2018-07-18" version="1">MVEFHLMGCSMKIPNELKIPLIVFTLESAVVAGFIVIFTFILKLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GU60</accession>
    <name>A0A2S9GU60_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative carboxypeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4091</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000027">
        <property type="protein sequence ID" value="PRC91196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91196">
        <property type="protein sequence ID" value="PRC91196"/>
        <property type="gene ID" value="S2091_4091"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004181">
        <property type="term" value="F:metallocarboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040626">
        <property type="entry name" value="Pepdidase_M14_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000834">
        <property type="entry name" value="Peptidase_M14"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18027">
        <property type="entry name" value="Pepdidase_M14_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00246">
        <property type="entry name" value="Peptidase_M14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00631">
        <property type="entry name" value="Zn_pept"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_M14" evidence="1">
        <location>
            <begin position="107"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="380" mass="42890" checksum="7D2B64342E8E1358" modified="2018-07-18" version="1">MSIKISSHFDAGAIEVVSTAQPSQINLNLRKDSNADFMQWFYFRLQGARDEACTLRILNAGAATYPSGWEGYRAVASYDREEWFRVDTEYDGKVLTIKHTPTEDSVYYAYFEPYSWERHLSLLGRAAYSPQVRIEDLGNTVDGRDLNMLVIGDEAAEQKVWVIARQHPGESMAEWLVEGMLDALLDVANPIARKILQKAVLYVVPNMNPDGSVRGNLRTNAAGANLNREWMTPSLETSPEVFYVKNKIHETGCDLFLDIHGDEGLPYNFVAGSEMLQGFTEQQMAEQNAFVQSFVAASPDFQTKFGYPTDKYYEDVLKLASKYVGHHFKCTSLTLELPFKDNADMPDDVVGWDGDRSAKLGEAMLQPILQHLNRNQVKTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GU72</accession>
    <name>A0A2S9GU72_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Stress responsive A/B Barrel Domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3956</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000025">
        <property type="protein sequence ID" value="PRC91285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91285">
        <property type="protein sequence ID" value="PRC91285"/>
        <property type="gene ID" value="S2091_3956"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013097">
        <property type="entry name" value="Dabb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07876">
        <property type="entry name" value="Dabb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00886">
        <property type="entry name" value="Dabb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51502">
        <property type="entry name" value="S_R_A_B_BARREL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Stress-response A/B barrel" evidence="1">
        <location>
            <begin position="2"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="100" mass="11278" checksum="7E15D11729E0583B" modified="2018-07-18" version="1">MIKHIVMWKLKEHAECASKATNAIKIKEQLATCANLVPGMLTLEVAIASPELEATYDVLLYTEFTDKAALDAYQEHPTHQAIKPFIGSVRLERQCMDYEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUG4</accession>
    <name>A0A2S9GUG4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">AhpC/TSA family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_3888</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000024">
        <property type="protein sequence ID" value="PRC91343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91343">
        <property type="protein sequence ID" value="PRC91343"/>
        <property type="gene ID" value="S2091_3888"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015036">
        <property type="term" value="F:disulfide oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017004">
        <property type="term" value="P:cytochrome complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013740">
        <property type="entry name" value="Redoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08534">
        <property type="entry name" value="Redoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0201">Cytochrome c-type biogenesis</keyword>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Thioredoxin" evidence="5">
        <location>
            <begin position="30"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC91343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="174" mass="18776" checksum="EA9D841562E80C61" modified="2018-07-18" version="1">MKSRFLITSLVAIVFGGFGLYFSSLHAEKPQVSDALYASSLPTVPAAPNGAAKSLAEYRNKVVVVNFWATWCGPCVQEMPELSAMQTELAAKKISFIGIGIDSPDSMAEFAKKYKITYPLFVAGMSGTQLATDLGNRSGGLPFTVILDKSGAVVKTYRGRLDMTQLRQDILAVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUI0</accession>
    <name>A0A2S9GUI0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Type IV-A pilus assembly ATPase PilB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_3940</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GSP E family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000024">
        <property type="protein sequence ID" value="PRC91395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91395">
        <property type="protein sequence ID" value="PRC91395"/>
        <property type="gene ID" value="S2091_3940"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009297">
        <property type="term" value="P:pilus assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013374">
        <property type="entry name" value="ATPase_typ4_pilus-assembl_PilB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001482">
        <property type="entry name" value="T2SS/T4SS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037257">
        <property type="entry name" value="T2SS_E_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007831">
        <property type="entry name" value="T2SS_GspE_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00437">
        <property type="entry name" value="T2SSE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05157">
        <property type="entry name" value="T2SSE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160246">
        <property type="entry name" value="SSF160246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02538">
        <property type="entry name" value="type_IV_pilB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00662">
        <property type="entry name" value="T2SP_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="T2SP_E" evidence="4">
        <location>
            <begin position="393"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS00662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC91395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="575" mass="63159" checksum="0301D622C2F1EAC7" modified="2018-07-18" version="1">MAEVINNPLSQNPMSGLARALLQANRLSMAQLDPIIKKTQIDKTPFIDALLQSGYIKSRELAVFCSETFGYSLMDIDAFNPGSFPEKIVDHKLMQTQRIIALAKRGNKVSIAISDPTNVQALDQIKFQTELIVEPIIVQHDLLVSLLDKLAKSSEQNLNELIGDEMDIDFGEADAGAAAAEAATTEVDDAPVVRFLNKILLDAINMGASDLHFEPFEKFYRIRFRVDGELREIAQPPLAIKEKLVSRIKVLSRLDISEKRVPQDGRMKLMMSQTRAIDFRVSTLPTLFGEKVVMRILDGSQAQMGIDALGYDPDQKAILMNAIQRPYGMVLVTGPTGSGKTVSLYTCLNVINKPGINISTAEDPAEINLPGVNQVNINDRAGLSFPVALKSFLRQDPDVIMVGEIRDLETADIAIKAAQTGHMVFSTLHTNDAPSTLTRLMNMGVAPFNIASSVILITAQRLTRRLCTCKKPIDILDQVLLDAGFEESMLDGTWTPYQPVGCERCSGSGYKGRVGIYQLMPITEEIERIILAHGSALDIENQAKSEGVRTLRESGLMKVKQGLTSLEEVLGCTNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUI7</accession>
    <name>A0A2S9GUI7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Inosine-uridine nucleoside N-ribohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_3913</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000024">
        <property type="protein sequence ID" value="PRC91368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91368">
        <property type="protein sequence ID" value="PRC91368"/>
        <property type="gene ID" value="S2091_3913"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016799">
        <property type="term" value="F:hydrolase activity, hydrolyzing N-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006139">
        <property type="term" value="P:nucleobase-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901564">
        <property type="term" value="P:organonitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.245.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001910">
        <property type="entry name" value="Inosine/uridine_hydrolase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023186">
        <property type="entry name" value="IUNH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036452">
        <property type="entry name" value="Ribo_hydro-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12304">
        <property type="entry name" value="PTHR12304"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01156">
        <property type="entry name" value="IU_nuc_hydro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53590">
        <property type="entry name" value="SSF53590"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="1 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="IU_nuc_hydro" evidence="3">
        <location>
            <begin position="7"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC91368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="331" mass="35700" checksum="2A67C03B35650B9B" modified="2018-07-18" version="1">MSTKHKVIFDTDPGVDDAMALYFALAHPDIEVLGITTIFGNVTVEQATENALYLTRIAGYEIPVAHGAPVPLAKPPGTPPGFIHGDDGLGNLTKRSPIKGQAENCSGAEYIVKMARAYPGEITLVAVAPLANLGLALKIEPNLPKLIKQVVLMAGTVTEPGNVSPVAEANVWNDPDAADLVFTAGWNLTMVGLDVTHRVVLPSSFFDALAAKQNHLAMTTLQHAVHFYCNFYSAIRPELGHACFAHDVLAFVYLVAPELFKTQEGRVRVATDGIANGQTMMDKHGKLFYPQPGWEPEKPVTHVCMQVDVDACIKLIDSTLGSAWLKEPLIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUL4</accession>
    <name>A0A2S9GUL4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3840</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000023">
        <property type="protein sequence ID" value="PRC91425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91425">
        <property type="protein sequence ID" value="PRC91425"/>
        <property type="gene ID" value="S2091_3840"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="64" mass="7292" checksum="5665E3C80CE6D286" modified="2018-07-18" version="1">MTPTSNDELLFVYEKLEDQLMQVINESDNVPHLATSGIRVQPKKPMNCYESKMRSYAALCEAGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUX8</accession>
    <name>A0A2S9GUX8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Isochorismatase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3798</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000022">
        <property type="protein sequence ID" value="PRC91520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91520">
        <property type="protein sequence ID" value="PRC91520"/>
        <property type="gene ID" value="S2091_3798"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.850">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000868">
        <property type="entry name" value="Isochorismatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036380">
        <property type="entry name" value="Isochorismatase-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00857">
        <property type="entry name" value="Isochorismatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52499">
        <property type="entry name" value="SSF52499"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Isochorismatase" evidence="1">
        <location>
            <begin position="14"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="190" mass="20740" checksum="CA4FB4EAC5B656E0" modified="2018-07-18" version="1">MTEITNTLANAASSILIVIDFQAKLIPLIFDGAQVTQRALLLAQAAKLLKIPVFGTEQQPLRLGASIPSLAGLYDLSVQKSTFDACAEPAFLAALEQLSAEPARDELCIVGCEAHVCVLQTVLGLLERGWRVKLVVDAIGSRLESNKLLAVQRAALHGAEIVSSEMLMFEWLRDSEHPHFREVLKLIKPM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVR3</accession>
    <name>A0A2S9GVR3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3567</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000019">
        <property type="protein sequence ID" value="PRC91812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91812">
        <property type="protein sequence ID" value="PRC91812"/>
        <property type="gene ID" value="S2091_3567"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024446">
        <property type="entry name" value="PXPV"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12778">
        <property type="entry name" value="PXPV"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015412585" evidence="2">
        <location>
            <begin position="25"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="90"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="110" mass="13227" checksum="A25078F7A6FE966B" modified="2018-07-18" version="1">MKKLLTLAAGLVAGTTLMMSAAYAGPVHVDLNIGIPLPVFVQPAPVYYQPEPVYVQPRAVYYGYRDYGWYQRQRREHEWHDRREWQEHHGYDRDYRDERRVEHHEDRGYH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVR6</accession>
    <name>A0A2S9GVR6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative glutamine amidotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3501</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000019">
        <property type="protein sequence ID" value="PRC91746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91746">
        <property type="protein sequence ID" value="PRC91746"/>
        <property type="gene ID" value="S2091_3501"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016811">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011697">
        <property type="entry name" value="Peptidase_C26"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044668">
        <property type="entry name" value="PuuD-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43235">
        <property type="entry name" value="PTHR43235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07722">
        <property type="entry name" value="Peptidase_C26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="262" mass="28937" checksum="BEDD4AE9CB733C0E" modified="2018-07-18" version="1">MLKKNTQHEKVSHRKPVVLMSMGAQERKGHDYQVMTVKYIKPLAEHAGCVPLLAPTCCGSEDIEQYLSMVDGVYLTGAGSNIDPALYGQENLTPDKQQDPNRDNFDIPLIHAALKMGLPIFAICRGMQELNVALGGDLHQKLYAEPNMLDHREDGDESVDEQYADAHQVRLVSNSWLSKLLEAEEIPVNSLHGQSIKTLGAGVQVLAHAEDGAIEAIHLPEVEQFTLGVQWHPEWKAAQNPNSIKIFAAFGDACRLQVQARS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVW0</accession>
    <name>A0A2S9GVW0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cytochrome c peroxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_3421</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000018">
        <property type="protein sequence ID" value="PRC91865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91865">
        <property type="protein sequence ID" value="PRC91865"/>
        <property type="gene ID" value="S2091_3421"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004852">
        <property type="entry name" value="Di-haem_cyt_c_peroxidsae"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03150">
        <property type="entry name" value="CCP_MauG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0349">Heme</keyword>
    <keyword evidence="3 4" id="KW-0408">Iron</keyword>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cytochrome c" evidence="6">
        <location>
            <begin position="77"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="6">
        <location>
            <begin position="242"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="103"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC91865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="395" mass="43170" checksum="EE8F710E10BB7440" modified="2018-07-18" version="1">MRASILILLVILTLATGSENVWAGEITLSTQCPASFEKQAGHCKLRSIYTDYASLQSAGVGGLKTGLPPLREGFSAEQMDLGRYLFFDPILSGNGKQSCASCHSPDKGFSDGRPRSIGASGQETTRNAPSLWNVGFLTKFFWDGRATSLEAQMKGPLYSTIEMASSPEKILANLNGNKEYRRLFALAYADTNVKNAEAKNASATSINIEQVYHAIAAFETTLISLNSRYDLYAHGVPDALTKPELEGLNVFRSFVARCAECHTPPLFTNQQIVVIGTPEAAGRSFDPGAGAISHDPNLRGGFKVPSLRNVELTAPYMHSGRFATLRDVVSFYNEGRGHAVPKNETLHLHWHIHEPKLSNAELDRLVDFLKTLTDESFKPQRPSVVPSGLPLMLNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVW8</accession>
    <name>A0A2S9GVW8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3407</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000018">
        <property type="protein sequence ID" value="PRC91851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91851">
        <property type="protein sequence ID" value="PRC91851"/>
        <property type="gene ID" value="S2091_3407"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="259" mass="28179" checksum="F0F99478F617A8A8" modified="2018-07-18" version="1">MLFGAKPRFVTFLSALCNEEKNATLVNLSAGLGRLGSDVVLLDARQSGASVAKWLEIQIVATLLDVAHQKRTIQQATMTTSQGFKLASFCRYQNTMPDFQPTTTLVMKLNKIVEKLGNSADIVLVDGELDDSNGLATVALEEGEIVIQVTNHPDSIKTAYSLIKRAHGKFGRRYYGVLVTGVNEFEAHRVYDAMAQAAGNFLSVPLNFVGYVPQDDFLRRASRSGRTVLDAFPTAGAAMAFSRLAQQMTGIDEFASLHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWE5</accession>
    <name>A0A2S9GWE5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cytochrome C biogenesis protein transmembrane region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_3177</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000016">
        <property type="protein sequence ID" value="PRC92042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92042">
        <property type="protein sequence ID" value="PRC92042"/>
        <property type="gene ID" value="S2091_3177"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017004">
        <property type="term" value="P:cytochrome complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003834">
        <property type="entry name" value="Cyt_c_assmbl_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013740">
        <property type="entry name" value="Redoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041017">
        <property type="entry name" value="Thioredoxin_10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02683">
        <property type="entry name" value="DsbD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08534">
        <property type="entry name" value="Redoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17991">
        <property type="entry name" value="Thioredoxin_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="40"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="70"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="123"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="162"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="7">
        <location>
            <begin position="257"/>
            <end position="424"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC92042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="605" mass="64972" checksum="34A79771A3D0665F" modified="2018-07-18" version="1">MILVLLVFLGGVLTILSPCILPVLPFVFSRAEQPFLKSGLPMLVGMAISFTAIATLAAVGGAWAVHINQYGRIFSLILLTLFALTLLSKRLADWVSQPFVAAGNRLLQPSTPSASSGGLVRSLVLGVATGLLWAPCAGPILGLVLTGAAISGPNTQTTLLLFAYAAGAATSLALAILVGGRVFFALKKSLGAGEWIRRGLGIAVLGAVTAILFGWDNSILTSLSTASTNSLEQSLVNSIHQNTPAPEADTSMAMGGAMTGAMAANNSMMMSNQAKSPKLPIEGNLPQLNGATSWLNSAPLTPEALHGKVVLVDFWTYSCINCLRSLPYVKSWYDKYKDHGLVVIGVHAPEFAFEKDADNVQHAVRDLGVQYPVALDNNYAIWQGFDNQYWPAHYFVDAQGQIRGHHFGEGNYTESEQTIRQLLTEAGYTDLPPLTASTPATDSQATGVQAASDEQHIQSPETYIGYSRAKNFISPDGIKQDSPQSYTLPSELKLNQWGLSGNWTVGQEQAVLNQASGKIAFRFLARDLHLVVGPGKNGKQVRFRVLLDRAAPAMNHGTDIDADGNGTIHEQRLYQLIRQSKLVGEHTFSIEFLDKDAQAFSFTFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWF5</accession>
    <name>A0A2S9GWF5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Clan AA aspartic protease, TIGR02281 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3187</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000016">
        <property type="protein sequence ID" value="PRC92052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92052">
        <property type="protein sequence ID" value="PRC92052"/>
        <property type="gene ID" value="S2091_3187"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05483">
        <property type="entry name" value="retropepsin_like_bacteria"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011969">
        <property type="entry name" value="Clan_AA_Asp_peptidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034122">
        <property type="entry name" value="Retropepsin-like_bacterial"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="SSF50630"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02281">
        <property type="entry name" value="clan_AA_DTGA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015592438" evidence="1">
        <location>
            <begin position="29"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="185" mass="19916" checksum="ADBC780137051739" modified="2018-07-18" version="1">MTIQTKVTLNSWLIIGVFLSLLTSSLQAFGDSTIQKCKRSDGSIFYQQDVCPPGTNSSTFAVNSDQSDSLTLYANSGHQYSTTLTINGVTVPGFIDTGATFVVVSLETAIKMHLAGEGFRAQYMQTANGVIRSANKTIPVIKVGKFELYNVEISIVANAPTLIGMSALSQLKFSNENGNMTLSKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWI0</accession>
    <name>A0A2S9GWI0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Growth inhibitor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3358</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000017">
        <property type="protein sequence ID" value="PRC92016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92016">
        <property type="protein sequence ID" value="PRC92016"/>
        <property type="gene ID" value="S2091_3358"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003477">
        <property type="entry name" value="PemK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011067">
        <property type="entry name" value="Plasmid_toxin/cell-grow_inhib"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33988">
        <property type="entry name" value="PTHR33988"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02452">
        <property type="entry name" value="PemK_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="116" mass="12459" checksum="DB3A705DFC9D1FE5" modified="2018-07-18" version="1">MAAYIPSRGDIVHLQFDPASGQEMKGAHFGLVISQKAFNARGLAMICPISQGAAASARTHGTVVTLMGLGVDTQGAVHCHQIKSLDWALRKAKFKEKVTRDIVDDVAARVEAIIFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWK1</accession>
    <name>A0A2S9GWK1_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Phosphoribosylglycinamide formyltransferase</fullName>
            <ecNumber evidence="3">2.1.2.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">5'-phosphoribosylglycinamide transformylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">GAR transformylase</fullName>
            <shortName evidence="3">GART</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">purN</name>
        <name evidence="5" type="ORF">S2091_3206</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>(6S)-10-formyltetrahydrofolate + N(1)-(5-phospho-beta-D-ribosyl)glycinamide = (6S)-5,6,7,8-tetrahydrofolate + H(+) + N(2)-formyl-N(1)-(5-phospho-beta-D-ribosyl)glycinamide</text>
            <dbReference type="Rhea" id="RHEA:15053"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="ChEBI" id="CHEBI:57454"/>
            <dbReference type="ChEBI" id="CHEBI:143788"/>
            <dbReference type="ChEBI" id="CHEBI:147286"/>
            <dbReference type="EC" id="2.1.2.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 3">Purine metabolism; IMP biosynthesis via de novo pathway; N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide from N(1)-(5-phospho-D-ribosyl)glycinamide (10-formyl THF route): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the GART family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.2" evidence="3"/>
    <dbReference type="EMBL" id="PUGF01000016">
        <property type="protein sequence ID" value="PRC92071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92071">
        <property type="protein sequence ID" value="PRC92071"/>
        <property type="gene ID" value="S2091_3206"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00126"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004644">
        <property type="term" value="F:phosphoribosylglycinamide formyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd08645">
        <property type="entry name" value="FMT_core_GART"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01930">
        <property type="entry name" value="PurN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002376">
        <property type="entry name" value="Formyl_transf_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036477">
        <property type="entry name" value="Formyl_transf_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004607">
        <property type="entry name" value="GART"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001555">
        <property type="entry name" value="GART_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00551">
        <property type="entry name" value="Formyl_trans_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53328">
        <property type="entry name" value="SSF53328"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00639">
        <property type="entry name" value="PurN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00373">
        <property type="entry name" value="GART"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Formyl_trans_N" evidence="4">
        <location>
            <begin position="8"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="5'-phosphoribosylglycinamide binding" evidence="3">
        <location>
            <begin position="18"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="10-formyltetrahydrofolate binding" evidence="3">
        <location>
            <begin position="96"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="3">
        <location>
            <position position="115"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="71"/>
        </location>
        <ligand>
            <name>(6S)-10-formyltetrahydrofolate</name>
            <dbReference type="ChEBI" id="CHEBI:57454"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="113"/>
        </location>
        <ligand>
            <name>(6S)-10-formyltetrahydrofolate</name>
            <dbReference type="ChEBI" id="CHEBI:57454"/>
        </ligand>
    </feature>
    <feature type="site" description="Raises pKa of active site His" evidence="3">
        <location>
            <position position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC92071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="200" mass="21907" checksum="C1CE0A181A37E730" modified="2018-07-18" version="1">MLYNTAMKNIVILISGRGSNMQAIVAAAQAQEWPARIAAVISNRADAEGLEFAAQHGIPTAVVVSKNYPSRAEFDTALQTQIEQFSPDLVVLAGFLRILTSEFVQHYAGRMINIHPSLLPNFTGLHTHRQALQAGALEHGATVHVVTAELDHGPILDQARVPVLPDDTEDSLASRVLAQEHILYPRVIRQILDGKLRLQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWL0</accession>
    <name>A0A2S9GWL0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3181</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000016">
        <property type="protein sequence ID" value="PRC92046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92046">
        <property type="protein sequence ID" value="PRC92046"/>
        <property type="gene ID" value="S2091_3181"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="174" mass="19427" checksum="19EC5D9FD5A8BCBF" modified="2018-07-18" version="1">MTASTNIILLPDAGPLITLAYADALDVLLLPGWSVQLVDMVLHEVTRNVTPTSEKLAQWVVDKQLSVLPTKTFAHYQKEKINSLVKTANLGELAIQEVMNGFALAKPLKNGVFLFEDHKIARASFLLPDNCRKVSTRAFLLFLEQKDWITSSAEIERRAIQAGRAFSQLHFPPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWL9</accession>
    <name>A0A2S9GWL9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative serine esterase (DUF676)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3226</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000016">
        <property type="protein sequence ID" value="PRC92091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92091">
        <property type="protein sequence ID" value="PRC92091"/>
        <property type="gene ID" value="S2091_3226"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007751">
        <property type="entry name" value="DUF676_lipase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05057">
        <property type="entry name" value="DUF676"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF676" evidence="1">
        <location>
            <begin position="15"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="1570" mass="177792" checksum="B62512F6FB194C52" modified="2018-07-18" version="1">MADLIKISKNHHEKNSHVIFLHGLNGDPYESWGASQNSKKKFWPKWLEKDITDLTVWSIGYHAAISRWRGEAMHFTERATNILELILAEPNLKNGEIILIGHSMGGLIIKQMLRTAESMGFQRFEADSFVKRVRRIAFIATPHLGSDQATWVDRLRIFIRPSAATASLLCNAPALRDLNIWYREWSAEYTVSHLILIESQTTKILGMIVKPESGDPGLLTRSIPIDANHITICKPSTPKSEVYTHILRFINTPSNTNHRRTTIENSIAHQSVKLETLITSTQNIGSLVENNFSGLTHSLLEQGEKTARLLGEKLQQAQNSSSISIARKFPSKLIDDEIQKNLLSLRRARNFGGFDSQDYAKRFAEQVSTGEFECGSDSIRSIALSWCSRILSRETDISQSEKYLQLAQQLGNSEEVAIADAFIISARGDLGSALNKLAIIPSSHARSASLYVAIQHKNEADVIDWLANAGLTIADLDPDGKSQLIILLFNLRRWKIACEHVESLDKDDYEFTPVLLHLAAITNLIQVIPEELRIVVLQQIPFDVDSFPLASDAQSLRLIKNAIDLFSRCETEARNLNCIDVANMSADYALWLKLRDPNDGQAALIALHTKLRDQRDSLRYVPFALKFGIQLDVAEVEKQIDRCMALTGEESFDGVMARFALVFAQENKKSAAEYFHQYREHLKKFVIPQSFNQVEINLLSGSGQFQLAENRLETLSQEGISEEEQNTLRRIISVAKEDNPTESRRMQFEKSGLISDLVSLVYFLKEQQDWKNLCDYGARLFAKTRALINAEDLALALSEENRYIELASFLREYPEFLSQSENLQTLWSWTLYREGLLNESAQALALLRTQRDHPNDRKLRINLAITSGDWESLAHYVEEEWTRRSERNANELMGTAQLAHYINAPRAKDLMLAAAAKGQDNATILMASYNLATSAGCEDNIEVGQWLQKAIDLSGDNGPVRRMSLQELLERKPEWDQQVNNALEKLTSGEIPIFLAARFLQRSLIDIFLVPALTNLSARDPRTRIIIPAYSGARQPVQQSNIQCIAIDAPSLLTMGTMKVLNTVSEAFDHIIIPHSTMGWLFEEKRNVSFHQPNRIKNARILRGLLANGTLKQFKKYQKPTADLITDIGEDLASFISEAMDNVPTSGANKFVIRSNPVYRINSLMTEVADLSTYSSCLCSCLAVVNKLKQKGLLTVAEDTHARSYLSLHENDWPQQPELSDNANIYLDDLSITYLQHIGILEKLENSGLSVYISNREVEEIDALLNYDQLTSEVTRIIEDVRSFVAIGIKSGRVKLAPVPEIHHINYHADQENDELNFRHHPSMEIFTAAKDVDALIIDDRYFNQHQNISDGTYITPILTTLDLVDLLHSRGKLDQARHFDIRTKVRLACYFAIPITTSELHHHLSLAETKNGHIIESAELKAIRENLLRICMSSFLKLPKETAWLDGIMQTLMSTLKKQWSEEIDEEIAAAKSDWLLIILDARGWAHCLEIDSDLQIADRTYYLQILGLLVTTEMSGPTRKKYFNWLDSRILFRLRDERPDVYSCLIERVKSIINNTTHVNELSEVTNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWP6</accession>
    <name>A0A2S9GWP6_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Bifunctional uridylyltransferase/uridylyl-removing enzyme</fullName>
            <shortName evidence="7">UTase/UR</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Bifunctional [protein-PII] modification enzyme</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Bifunctional nitrogen sensor protein</fullName>
        </alternativeName>
        <domain>
            <recommendedName>
                <fullName evidence="7">[Protein-PII] uridylyltransferase</fullName>
                <shortName evidence="7">PII uridylyltransferase</shortName>
                <shortName evidence="7">UTase</shortName>
                <ecNumber evidence="7">2.7.7.59</ecNumber>
            </recommendedName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="7">[Protein-PII]-UMP uridylyl-removing enzyme</fullName>
                <shortName evidence="7">UR</shortName>
                <ecNumber evidence="7">3.1.4.-</ecNumber>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name evidence="7" type="primary">glnD</name>
        <name evidence="10" type="ORF">S2091_3058</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>[protein-PII]-L-tyrosine + UTP = [protein-PII]-uridylyl-L-tyrosine + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:13673"/>
            <dbReference type="Rhea" id="RHEA-COMP:12147"/>
            <dbReference type="Rhea" id="RHEA-COMP:12148"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
            <dbReference type="ChEBI" id="CHEBI:46858"/>
            <dbReference type="ChEBI" id="CHEBI:90602"/>
            <dbReference type="EC" id="2.7.7.59"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>[protein-PII]-uridylyl-L-tyrosine + H2O = [protein-PII]-L-tyrosine + H(+) + UMP</text>
            <dbReference type="Rhea" id="RHEA:48600"/>
            <dbReference type="Rhea" id="RHEA-COMP:12147"/>
            <dbReference type="Rhea" id="RHEA-COMP:12148"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:46858"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="ChEBI" id="CHEBI:90602"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="activity regulation">
        <text evidence="7">Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.</text>
    </comment>
    <comment type="domain">
        <text evidence="7">Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the GlnD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.59" evidence="7"/>
    <dbReference type="EC" id="3.1.4.-" evidence="7"/>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92142">
        <property type="protein sequence ID" value="PRC92142"/>
        <property type="gene ID" value="S2091_3058"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008773">
        <property type="term" value="F:[protein-PII] uridylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008081">
        <property type="term" value="F:phosphoric diester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006807">
        <property type="term" value="P:nitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006808">
        <property type="term" value="P:regulation of nitrogen utilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00277">
        <property type="entry name" value="PII_uridylyl_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013546">
        <property type="entry name" value="PII_UdlTrfase/GS_AdlTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002934">
        <property type="entry name" value="Polymerase_NTP_transf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010043">
        <property type="entry name" value="UTase/UR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47320">
        <property type="entry name" value="PTHR47320"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08335">
        <property type="entry name" value="GlnD_UR_UTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01966">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01909">
        <property type="entry name" value="NTP_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006288">
        <property type="entry name" value="PII_uridyltransf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01693">
        <property type="entry name" value="UTase_glnD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51831">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 7" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="2 7 10" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 7 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HD" evidence="9">
        <location>
            <begin position="436"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="domain" description="ACT" evidence="8">
        <location>
            <begin position="675"/>
            <end position="754"/>
        </location>
    </feature>
    <feature type="domain" description="ACT" evidence="8">
        <location>
            <begin position="783"/>
            <end position="851"/>
        </location>
    </feature>
    <feature type="region of interest" description="Uridylyltransferase" evidence="7">
        <location>
            <begin position="1"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC92142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="851" mass="97263" checksum="87798A46496AB848" modified="2018-07-18" version="1">MQPLAQKLKEQLKARHQLITAAFSQNQKKPEALLHDICHSVDTALIELWQALALPNDVSLIGVGGYGRGELFPYSDVDVLVLLPHAADDALRVKLELLVQQFWDLGLEIGHSIRTIDECLQESKADITVQTSLLEARLVTGSRKSFRALREHYNAAMNPQAFFQAKTLELRQRHVKFEDTPYSLEPNCKESPGGLRDLQVILWISKAAKLGNSWSELAARGLITGPEARQLRRNERAFKDIRIRLHIFAKRREDRLVFDVQTPIAETFGFVATPTRRSSEYLMQRYYWAAKAVTQLNTILLQNIEAQLFISTSKPHAINADFNEINGFIEPVDPQLFEHRPSAMLELYLLLSQQTELKGMSAPTMRALWHARFKINSKFRRDPINHDLFLQILQAPQGVTHALRGMNQMSILGRYLPNFRRIIGQMQHDLFHVYTVDQHILMVVRNLRRFTMPEHAHEYPFCSQLIANFPQHWVLYVAALFHDIAKGRNGDHSHLGGEDARRFCRQHGMAKDKTELVVFLVEHHLLMSQVAQKQDLSDPEVIQHFAKVVKDERHLTALYLLTVSDIRGTSPKVWNAWKGKLLEDLYHLTLRALGGEIPSPDRELKNRQDEALKNLRLYGLPENAHAELWKQLDVVYFLRNDASDIVWQTRVFYDKVNSEKPAVKCRTAPIGEGLQVAVYIKDQPDLFARICSYFDAKSFSILDAKIHTTQHDYALDTFLISASAFSKNYRDIINLVEHELTKLLSSQTALPVPSKGRLSRLSRTFPITPTVGLLPDERGQYYLLSVTANDRNGLLYSIAKVLAKYKINLHTAKIMTLGERVEDVFLIDGAALQNSRTQIQLETDLLDALTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWQ5</accession>
    <name>A0A2S9GWQ5_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ</fullName>
            <ecNumber evidence="9">4.2.1.59</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase</fullName>
            <shortName evidence="9">(3R)-hydroxymyristoyl-ACP dehydrase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Beta-hydroxyacyl-ACP dehydratase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">fabZ</name>
        <name evidence="10" type="ORF">S2091_3073</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8 9">Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>a (3R)-hydroxyacyl-[ACP] = a (2E)-enoyl-[ACP] + H2O</text>
            <dbReference type="Rhea" id="RHEA:13097"/>
            <dbReference type="Rhea" id="RHEA-COMP:9925"/>
            <dbReference type="Rhea" id="RHEA-COMP:9945"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:78784"/>
            <dbReference type="ChEBI" id="CHEBI:78827"/>
            <dbReference type="EC" id="4.2.1.59"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the thioester dehydratase family. FabZ subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.59" evidence="9"/>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92157">
        <property type="protein sequence ID" value="PRC92157"/>
        <property type="gene ID" value="S2091_3073"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008659">
        <property type="term" value="F:(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008693">
        <property type="term" value="F:3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047451">
        <property type="term" value="F:3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004317">
        <property type="term" value="F:3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009245">
        <property type="term" value="P:lipid A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00406">
        <property type="entry name" value="FabZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013114">
        <property type="entry name" value="FabA_FabZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010084">
        <property type="entry name" value="FabZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30272">
        <property type="entry name" value="PTHR30272"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07977">
        <property type="entry name" value="FabA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01750">
        <property type="entry name" value="fabZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 9" id="KW-0441">Lipid A biosynthesis</keyword>
    <keyword evidence="4 9" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="6 9" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7 9" id="KW-0456">Lyase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" evidence="9">
        <location>
            <position position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00025049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC92157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="160" mass="17774" checksum="840EF725F9597067" modified="2018-07-18" version="1">MNSLDINQIKEYLPHRYPMLLVDRVLNWESGKTITAIKNVTANEEFFNGHFPNKPVMPGVLMIEAMAQAAALLSFLTMGQKPDENTLVYFLGIDNARFKRPVEPGDQLKLEVEIVKVARGIWKYKATASVDGQLAVEADLMCTLRTVESSAAKPAPVVPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWS1</accession>
    <name>A0A2S9GWS1_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase</fullName>
            <ecNumber evidence="2">2.5.1.145</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">lgt</name>
        <name evidence="3" type="ORF">S2091_3241</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + L-cysteinyl-[prolipoprotein] = H(+) + S-1,2-diacyl-sn-glyceryl-L-cysteinyl-[prolipoprotein] + sn-glycerol 1-phosphate</text>
            <dbReference type="Rhea" id="RHEA:56712"/>
            <dbReference type="Rhea" id="RHEA-COMP:14679"/>
            <dbReference type="Rhea" id="RHEA-COMP:14680"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:57685"/>
            <dbReference type="ChEBI" id="CHEBI:64716"/>
            <dbReference type="ChEBI" id="CHEBI:140658"/>
            <dbReference type="EC" id="2.5.1.145"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; lipoprotein biosynthesis (diacylglyceryl transfer).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the Lgt family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.145" evidence="2"/>
    <dbReference type="EMBL" id="PUGF01000016">
        <property type="protein sequence ID" value="PRC92106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92106">
        <property type="protein sequence ID" value="PRC92106"/>
        <property type="gene ID" value="S2091_3241"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00664"/>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008961">
        <property type="term" value="F:phosphatidylglycerol-prolipoprotein diacylglyceryl transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042158">
        <property type="term" value="P:lipoprotein biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01147">
        <property type="entry name" value="Lgt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001640">
        <property type="entry name" value="Lgt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30589">
        <property type="entry name" value="PTHR30589"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01790">
        <property type="entry name" value="LGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00544">
        <property type="entry name" value="lgt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01311">
        <property type="entry name" value="LGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="92"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="179"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="204"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="240"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="142"/>
        </location>
        <ligand>
            <name>1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol)</name>
            <dbReference type="ChEBI" id="CHEBI:64716"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="269" mass="30313" checksum="C90C2F8A49470F71" modified="2018-07-18" version="1">MLIHPMPDPIALQIGPLAIHWYGLMYMLAFILFLAVGRIRLKQAHIAAAGWRYEHLEDMLFYGVLGVVVGGRLGEVLFYHPEYYSEHLLEIFAVWKGGMSFHGGFLGVLLALAIWSKKSGRNVLDVYDLIAPLVPLGYACGRIGNFINAELWGRVADPSLPWAMIWPNVDQLPRHPSPIYQALVDGVLAFILLWIYARKQRPRLAVGAMYVLLYGCARFFTEYFRVPDWTVDVVGVQISAGQVLSVPMIIFGIGALYFSYHFEKKPVTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWU7</accession>
    <name>A0A2S9GWU7_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Molybdenum transport system permease</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">S2091_3113</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 9">Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell inner membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92197">
        <property type="protein sequence ID" value="PRC92197"/>
        <property type="gene ID" value="S2091_3113"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015098">
        <property type="term" value="F:molybdate ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011867">
        <property type="entry name" value="ModB_ABC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02141">
        <property type="entry name" value="modB_ABC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 9" id="KW-0500">Molybdenum</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="15"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="47"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="81"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="193"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="10">
        <location>
            <begin position="9"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC92197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="227" mass="24481" checksum="EF5B478AD3377AA6" modified="2018-07-18" version="1">MDAADLGAIWLTLKLATLTTVILLLLGTPLAWWLARTKSRSKNVIRTLVALPLVLPPTVIGFYLLVFMGPHGAFGQLTQTLGLGLLPFTFSGLVIASMLYSMPFVVQPLYNAFEAIGERPLEVAATLRATPLDTFFSVVLPLAKPGYLTATVMGFAHTVGEFGVVLMIGGNIADKTRVVSVQIYDHVDALEYAHAHSLSAVMLVFSFVVLLLLYKFNPTNSAGKSSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWX3</accession>
    <name>A0A2S9GWX3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">RNA pseudouridylate synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3117</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92201">
        <property type="protein sequence ID" value="PRC92201"/>
        <property type="gene ID" value="S2091_3117"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140098">
        <property type="term" value="F:catalytic activity, acting on RNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009982">
        <property type="term" value="F:pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034470">
        <property type="term" value="P:ncRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001522">
        <property type="term" value="P:pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006224">
        <property type="entry name" value="PsdUridine_synth_RluC/D_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006145">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00849">
        <property type="entry name" value="PseudoU_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01129">
        <property type="entry name" value="PSI_RLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PseudoU_synth_2" evidence="1">
        <location>
            <begin position="103"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="305" mass="35111" checksum="2C2D97BD0FD0CA44" modified="2018-07-18" version="1">MSPKQYLSANPPLPIRDGVAPSYLWLQKGEWSSLLEFLIQRFPDVSSEIWQSRMARGEVVNETGAPYSATSPYRWGGRIFYYREIEAETPIPFEEQILFQDQHILVVDKPHFLPVIPTGRFLHETLLVRLKNKYHFHDLTPIHRLDRETAGVMIFSINLASRGAYQALFQQRTVQKEYEALAPNLIGHELPLTYRSRMAPGTPFFRMQEVPGIANSETRIELIEQISGQVSRYRLHPLSGRKHQLRVHLAALGIPILNDAFYPIALPCKADDMSQPLQLLARSIGFNDPITGQERYFESQRKLVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GX20</accession>
    <name>A0A2S9GX20_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3164</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92248">
        <property type="protein sequence ID" value="PRC92248"/>
        <property type="gene ID" value="S2091_3164"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036661">
        <property type="entry name" value="Luciferase-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51679">
        <property type="entry name" value="SSF51679"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="58" mass="6288" checksum="C7949A6FEEFA7F00" modified="2018-07-18" version="1">MLDQVLSCSARGSKETVAQQMAAFIARTGADELMITSQIFDHAARLRSYEITAEIAGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GX44</accession>
    <name>A0A2S9GX44_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">3-oxoacid CoA-transferase, B subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2953</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 3-oxoacid CoA-transferase subunit B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92294">
        <property type="protein sequence ID" value="PRC92294"/>
        <property type="gene ID" value="S2091_2953"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008410">
        <property type="term" value="F:CoA-transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012791">
        <property type="entry name" value="3-oxoacid_CoA-transf_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004165">
        <property type="entry name" value="CoA_trans_fam_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004164">
        <property type="entry name" value="CoA_transf_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13707">
        <property type="entry name" value="PTHR13707"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01144">
        <property type="entry name" value="CoA_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00882">
        <property type="entry name" value="CoA_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02428">
        <property type="entry name" value="pcaJ_scoB_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01274">
        <property type="entry name" value="COA_TRANSF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="213" mass="22346" checksum="E092CFDD36980551" modified="2018-07-18" version="1">MAWNRDEMAARAAQELQDGFYVNLGIGLPTMVANHVPTGMEVWLQSENGLLGIGPFPTEEQVDPDLINAGKQTVTTLPGSSIFSSADSFAMIRGGKINLAILGAMQVSQTGDLANWMIPGKMVKGMGGAMDLVAGVGRVVVLMEHVAKGDSHKILNSCNLPLTGVGVVNRIITDLGVIDITPNGLKLAELAPGVSVEEIITKTEAKLDVSALV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GX53</accession>
    <name>A0A2S9GX53_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Threonine--tRNA ligase</fullName>
            <ecNumber evidence="12">6.1.1.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Threonyl-tRNA synthetase</fullName>
            <shortName evidence="12">ThrRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">thrS</name>
        <name evidence="15" type="ORF">S2091_2949</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>ATP + L-threonine + tRNA(Thr) = AMP + diphosphate + H(+) + L-threonyl-tRNA(Thr)</text>
            <dbReference type="Rhea" id="RHEA:24624"/>
            <dbReference type="Rhea" id="RHEA-COMP:9670"/>
            <dbReference type="Rhea" id="RHEA-COMP:9704"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78534"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="12">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.3" evidence="12"/>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92290">
        <property type="protein sequence ID" value="PRC92290"/>
        <property type="gene ID" value="S2091_2949"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004829">
        <property type="term" value="F:threonine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006435">
        <property type="term" value="P:threonyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00771">
        <property type="entry name" value="ThrRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00184">
        <property type="entry name" value="Thr_tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002314">
        <property type="entry name" value="aa-tRNA-synt_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004154">
        <property type="entry name" value="Anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036621">
        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004095">
        <property type="entry name" value="TGS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012676">
        <property type="entry name" value="TGS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002320">
        <property type="entry name" value="Thr-tRNA-ligase_IIa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018163">
        <property type="entry name" value="Thr/Ala-tRNA-synth_IIc_edit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033728">
        <property type="entry name" value="ThrRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012947">
        <property type="entry name" value="tRNA_SAD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11451">
        <property type="entry name" value="PTHR11451"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03129">
        <property type="entry name" value="HGTP_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02824">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00587">
        <property type="entry name" value="tRNA-synt_2b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07973">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01047">
        <property type="entry name" value="TRNASYNTHTHR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00863">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55186">
        <property type="entry name" value="SSF55186"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81271">
        <property type="entry name" value="SSF81271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00418">
        <property type="entry name" value="thrS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51880">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 12" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="8 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 12" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 12 15" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10 12" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 12" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 12" id="KW-0820">tRNA-binding</keyword>
    <keyword evidence="7 12" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="TGS" evidence="14">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="13">
        <location>
            <begin position="242"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="region of interest" description="Catalytic" evidence="12">
        <location>
            <begin position="242"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="333"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="384"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="510"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="PRC92290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="635" mass="71803" checksum="C5B8E86E716FCCC0" modified="2018-07-18" version="1">MVSVRLPDGSQRQFDAPVTVAQVAASIGAGLAKAALAGKVNGQLVDTSFLIEADADLAIVTEKDPEGLEVIRHSTAHLLAYAVKQLYPDAQVTIGPVIDNGFYYDFSYKRPFTPDDLVLIEKKMAELAKKDEVITRKVLPRDEAVAYFTSIGEAYKAEIISSIPADQDVSLYTEGNFTDLCRGPHVPSTGKLKVFKLMKLAGAYWRGDSKNEMLQRVYGTAWIKKEDQEAYLFMLEEAEKRDHRKLGKALDLFHMQEEAPGLVFWHAKGWTIWQQVEQYMRQVYQDGGYQEVKTPQILDRTLWEKTGHWENYRESMFATESENRNYALKPMNCPGHLQIFNTGLRSYRELPLRFGEFGQCHRNETSGALHGIMRVRGFTQDDGHIFCTEEQIAQEVMTFHPQAMKVYADFGFHNIDIKIATRPDNRIGTEEDWDRAEESLRSALRACGLTWQELPGEGAFYGPKIEYHLKDSLGRSWQVGTVQIDPSMPVRLGAEYVAEDNSRKIPIMLHRAIVGSMERFIGVLIENFAGAFPLWLSPVQVVVTNISDSQAEYAKSVAESLKKQGFRVNLDLRNEKITYKIREHSVQKVPYIIVIGDKERDASTVAVRTRGNLDLGVMPVSALVERLNHEIATKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GX78</accession>
    <name>A0A2S9GX78_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Spherulation-specific family 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2984</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92325">
        <property type="protein sequence ID" value="PRC92325"/>
        <property type="gene ID" value="S2091_2984"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021986">
        <property type="entry name" value="Spherulin4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35040">
        <property type="entry name" value="PTHR35040"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12138">
        <property type="entry name" value="Spherulin4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015516366" evidence="2">
        <location>
            <begin position="24"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="276" mass="28785" checksum="C51A9CE8DBE89F1B" modified="2018-07-18" version="1">MKKTPLLISLLLAINLIALTACGGGGSSSSPASSTTPPVTPPTTPPVTPTGASILVPLYEDPSDTKTWNAIISAKAANPTVPIVAIINPNNGPGNSLDPTYAAAVAQLKAAGIIVYGYIATNSGGQSLTSMEAQMSQYVQWYGTTGMFFDEMAYSSGFESYYSALTQYAKSLGMLTTIGNPGSDTLPSYIGTVSTIVIFEQAGYPTTSFLSGGWHATYAPSNFAYISYGVPTFSAATELANAPYVQYQYISDQTGANPYNALPSYFASEVSTLASK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXC1</accession>
    <name>A0A2S9GXC1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3017</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92358">
        <property type="protein sequence ID" value="PRC92358"/>
        <property type="gene ID" value="S2091_3017"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005229">
        <property type="entry name" value="CHP00255"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013551">
        <property type="entry name" value="DUF1732"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013527">
        <property type="entry name" value="YicC-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30636">
        <property type="entry name" value="PTHR30636"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08340">
        <property type="entry name" value="DUF1732"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03755">
        <property type="entry name" value="YicC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00255">
        <property type="entry name" value="TIGR00255"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YicC_N" evidence="1">
        <location>
            <begin position="1"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1732" evidence="2">
        <location>
            <begin position="212"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="296" mass="33681" checksum="6A008957C3BA021B" modified="2018-07-18" version="1">MTGYAVTSRDVDAGSMTIEIKSVNSRFLDLQFRMNDDFRAFEPSFREAIITRITRGKVECRFSFARKEQQQNNKTMNPVVLSQLAQFQHDLKIQFPESAALTMHEMLRWPGVIEENTVSDDGLTAHAMECMLGTLEAFVLSREREGNALQVVLINKISEMEAIVERISPIIPQLIAQFQQKSVNRLQEALGMTNGNNLPTISREEVMDRIRQEVALYGIRIDIAEELTRLSGHLTETRHILNKGGQVGKRLDFMMQELNREANTLGSKAALKELADAAMELKLLIEQMREQVQNLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXG8</accession>
    <name>A0A2S9GXG8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2776</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92401">
        <property type="protein sequence ID" value="PRC92401"/>
        <property type="gene ID" value="S2091_2776"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008407">
        <property type="entry name" value="Brnchd-chn_aa_trnsp_AzlD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05437">
        <property type="entry name" value="AzlD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="73"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="107" mass="11844" checksum="6531EE94BACAD5F1" modified="2018-07-18" version="1">MSDLTLWIVIALLTLSTFITRATFWLIGHHINLPKRVHEALRFAPACALAAILIPDFLTNHHQIELSITNPQLVAGVCASVFFLIKPSMLGTIFFGMAVFTTVRLLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXM8</accession>
    <name>A0A2S9GXM8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major Facilitator Superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_2844</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92469">
        <property type="protein sequence ID" value="PRC92469"/>
        <property type="gene ID" value="S2091_2844"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="21"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="58"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="111"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="177"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="225"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="263"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="294"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="319"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="351"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="381"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="24"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC92469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="412" mass="44552" checksum="4E51D21C123B4949" modified="2018-07-18" version="1">MQTAIDQLSPTKSAHDNEKTGFRVLGAISFAHFLNDMIQSLILSIYPLLKGDFHLNFAQIGLITLTYQLTASILQPLVGIYTDKHPKPYSLALGMGCTLVGLLLLSVAPNYGMVLLAAALVGTGSSIFHPESSRVARMASGGQHGLAQSIFQVGGNAGSSMGPLLAANIIIPHGQSSIAWFSLAALLAIVVLLQIGNWYKRKRLEIKNKPAKAQHQQLVLPRKKIIFSISILLTLIFSKYFYMASMSSYFTFYLISKFHLSVQAAQIHLFIFLFSVAAGSLLGGPIGDRIGRKLVIWVSILGVAPFTLMLPYADLFWTGVLTVIIGLILSSAFSAILVFAQELVPGKVGTVSGLFFGFAFGMGGLGAAALGKLADMTDINYVYHVCSFLPLIGLLAAFLPDLDRQRRQLMQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXR6</accession>
    <name>A0A2S9GXR6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2887</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92512">
        <property type="protein sequence ID" value="PRC92512"/>
        <property type="gene ID" value="S2091_2887"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="4"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="293" mass="31716" checksum="205679004BBE2140" modified="2018-07-18" version="1">MRRYDLELLHTLATVAETGSLSAASLRLSRSQSAVSEQIRKLEESCGQILFLRGKKGSTLTPVGQRLLGHARSMLSLNDAVYLDMQGISLAGELRLAITDYFQPAGLAAILKRLHDQYPALRLHVSVRKSVEIEQTSSADEFDIGLSMRIVGEPIINAQKPDSPHKCIPIRREPLAWVASPSFVMRELEPLPLIALPGTCSQQRYMLAILKESGVAHYVAHSASGVLGLQSALSAGLGVSCLNASAVPAKVTAFRGRKGLPILPEVEFNLIVPHVFNSAFAAEAAAMLAQQFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXT9</accession>
    <name>A0A2S9GXT9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2895</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92520">
        <property type="protein sequence ID" value="PRC92520"/>
        <property type="gene ID" value="S2091_2895"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015690176" evidence="1">
        <location>
            <begin position="24"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="138" mass="14913" checksum="0972ABBC05D26912" modified="2018-07-18" version="1">MNITMIKKKLLLLLAIIVFGNYAQPPDVPPKNIKMCWKGPTISYSVGDNEECPDTEIQCKKIGGHWLGDNGETGLGSGCNPPTHDVGKSCKKGSDCEGYCVPEKPASESSACVCSNVKLLYAGVQYCTEHGVTYRPPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXU6</accession>
    <name>A0A2S9GXU6_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF58 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2597</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92542">
        <property type="protein sequence ID" value="PRC92542"/>
        <property type="gene ID" value="S2091_2597"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002881">
        <property type="entry name" value="DUF58"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01882">
        <property type="entry name" value="DUF58"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="29"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="domain" description="DUF58" evidence="2">
        <location>
            <begin position="209"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="323" mass="35939" checksum="786FE0645524FEB4" modified="2018-07-18" version="1">MLDNIQRKIIFWQHPAASSKELILDRQRVYILPSKAGLIYGLMLLSIFITAINYGLNLGYALDFILISCAWLGILLTFRNLAGLGLDASGSPAVFSGELAHFSVHLNNHSKRARYAIAIGFDKSSMQMVDIPEHSSHSMTLATQTTQRGWMPCPRIRLQTSFPFGLLNAWSYWKTTQKILVYPAPELNPPPLPYAAMSASGHELTAGQDEFSGVRNYQVGDSLKQLAWRQMARQSAGGNEVLLSKHFEGGLKKICVLDFDDLPLQFGAEQKLSRLCAWLLKAEQEQVSYAFKLGAEQFALNSGEDHQRCCLTALALFGIGENR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXV3</accession>
    <name>A0A2S9GXV3_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ribonuclease VapC</fullName>
            <shortName evidence="5">RNase VapC</shortName>
            <ecNumber evidence="5">3.1.-.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Toxin VapC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">vapC</name>
        <name evidence="6" type="ORF">S2091_2610</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Toxic component of a toxin-antitoxin (TA) system. An RNase.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the PINc/VapC protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="5"/>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92555">
        <property type="protein sequence ID" value="PRC92555"/>
        <property type="gene ID" value="S2091_2610"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004540">
        <property type="term" value="F:ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090729">
        <property type="term" value="F:toxin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00265">
        <property type="entry name" value="VapC_Nob1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006226">
        <property type="entry name" value="Mtu_PIN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022907">
        <property type="entry name" value="VapC_family"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="SSF88723"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00028">
        <property type="entry name" value="Mtu_PIN_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 5" id="KW-0540">Nuclease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0800">Toxin</keyword>
    <keyword evidence="1 5" id="KW-1277">Toxin-antitoxin system</keyword>
    <feature type="binding site" evidence="5">
        <location>
            <position position="6"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="106"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC92555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="143" mass="15647" checksum="E100AFFC2C66F7BD" modified="2018-07-18" version="1">MRYLLDVNVLIALIDPAHIYHDAAHNWFSNQGHQAWATCPLTENDVLRIVGHARYPNSPGTPSAVVTSLMGLCSLPGHEFWSDSISLLDVKKVDVKRLLSSDQVTDSYLLALACAHGGQLATFDRRLVADAVHGGKQGLYLIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXW6</accession>
    <name>A0A2S9GXW6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">PBP4: D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2606</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92551">
        <property type="protein sequence ID" value="PRC92551"/>
        <property type="gene ID" value="S2091_2606"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004185">
        <property type="term" value="F:serine-type carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000667">
        <property type="entry name" value="Peptidase_S13"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30023">
        <property type="entry name" value="PTHR30023"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02113">
        <property type="entry name" value="Peptidase_S13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00922">
        <property type="entry name" value="DADACBPTASE3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00666">
        <property type="entry name" value="PBP4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015617823" evidence="2">
        <location>
            <begin position="23"/>
            <end position="479"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="479" mass="52137" checksum="68C66EB6013997C2" modified="2018-07-18" version="1">MRLFFATLFFTCTALSSTSLHAQSLPPTVTQALQKARVPLDALGVYVQEVTQPSQASTPLISWQADQPLQPASTMKLVTSYAALDLLGPAYSWKTSVYMTGQMAGDVLQGDLILQGGGDPRLVVENFWTLLRQIRAAGIREIQGNLILDSSWMEPQNFDAADFDGDPTRPYNVGPDALLVNFNVMNLQLHNDAGGLRVTTLTPLALQSSVNVRLVNGACGEWRDKLTPTFSMAQHKINVALSGTYPSSCGDKTWLLQPYPLTHGDYVGALFRELWQETGGQFNGEVQQGVLPVLPAMAGLVTEMRSESLPEILRDMNKYSNNVMTRLVMLTLDKEASQQAANPARAAQLIQQWFAHIGIDAQGLQMENGSGLSRTERISAYQMGRMLNHAFASPVMPELMSSLPVLGVDGTMKKRALNQAVAGHAHIKSGSLEGVRAIAGYVLAASGKRYVVVCFVNHKNAVQSSAAQDELLQWIYANG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GY04</accession>
    <name>A0A2S9GY04_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative esterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2646</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92591">
        <property type="protein sequence ID" value="PRC92591"/>
        <property type="gene ID" value="S2091_2646"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003140">
        <property type="entry name" value="PLipase/COase/thioEstase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02230">
        <property type="entry name" value="Abhydrolase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Abhydrolase_2" evidence="1">
        <location>
            <begin position="14"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="218" mass="24104" checksum="DC3882A04060F0D9" modified="2018-07-18" version="1">MTLATIQIETAPNPTVSVIWMHGLGADGNDFVPIVHELDLHGCPAIRFVFPNAPHIPVTVNGGYVMPAWYDIRTADIANREDETGIRASQAAIEELIEIEHTRGAQKIILAGFSQGCAMTLQTGLRHSNKLAGLLCLSGYVPLYQNVARERHSANQGTPIFMAHGNADPIIPLQRAEQSRDLLTQLGYEVEWHEYPMQHSVCIPEISDMGAWFRRVLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GY24</accession>
    <name>A0A2S9GY24_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Ribonuclease 3</fullName>
            <ecNumber evidence="7">3.1.26.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Ribonuclease III</fullName>
            <shortName evidence="7">RNase III</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rnc</name>
        <name evidence="11" type="ORF">S2091_2663</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>Endonucleolytic cleavage to 5'-phosphomonoester.</text>
            <dbReference type="EC" id="3.1.26.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ribonuclease III family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.26.3" evidence="7"/>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92608">
        <property type="protein sequence ID" value="PRC92608"/>
        <property type="gene ID" value="S2091_2663"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004525">
        <property type="term" value="F:ribonuclease III activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00593">
        <property type="entry name" value="RIBOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00104">
        <property type="entry name" value="RNase_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014720">
        <property type="entry name" value="dsRBD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011907">
        <property type="entry name" value="RNase_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000999">
        <property type="entry name" value="RNase_III_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036389">
        <property type="entry name" value="RNase_III_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11207">
        <property type="entry name" value="PTHR11207"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00035">
        <property type="entry name" value="dsrm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14622">
        <property type="entry name" value="Ribonucleas_3_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00358">
        <property type="entry name" value="DSRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00535">
        <property type="entry name" value="RIBOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69065">
        <property type="entry name" value="SSF69065"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02191">
        <property type="entry name" value="RNaseIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50137">
        <property type="entry name" value="DS_RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00517">
        <property type="entry name" value="RNASE_3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50142">
        <property type="entry name" value="RNASE_3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 7" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 7" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="4 7" id="KW-0540">Nuclease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7 8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="7" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="7" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="7" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="RNase III" evidence="10">
        <location>
            <begin position="4"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="DRBM" evidence="9">
        <location>
            <begin position="153"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="43"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="115"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="39"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="112"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="115"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC92608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="280" mass="30429" checksum="B7FCF66C4BCB8CDC" modified="2018-07-18" version="1">MSNDTLLQNRLGHVFNDMTLLQQALTHRSHSVLHNERLEFLGDSVLNCVVASLLFQKYSTIDEGDLSRVRANLVKQQSLYEIALRLDLAQFLRLGEGELKSGGFRRPSILADTLEALFGAIFLDAGFNAARDVIFGLYLPILETVDPATLGKDAKTLLQEYLQSKKIALPVYTVAATHGAAHNQEFEVECSIPKLEIHVFGTGGSRRAGEQAAAKMALEAALAMLSKSPVAKRKSKPRTTQLKLAGIATVQTDEVVSDKTKSPTVAITTGSNNTTLPKIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYD1</accession>
    <name>A0A2S9GYD1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phage Mu protein F like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2721</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92666">
        <property type="protein sequence ID" value="PRC92666"/>
        <property type="gene ID" value="S2091_2721"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006528">
        <property type="entry name" value="Phage_head_morphogenesis_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017029">
        <property type="entry name" value="Phage_head_put"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04233">
        <property type="entry name" value="Phage_Mu_F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF034565">
        <property type="entry name" value="UCP034565"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phage_Mu_F" evidence="1">
        <location>
            <begin position="147"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="350" mass="38359" checksum="1AB6EE4A0C60E483" modified="2018-07-18" version="1">MGAVDAAIFEAMIAHAMNILRFSAGVNKAILELLTQLSQDLVKKLQESDLTEFNQQRTQKLLRESDAIINNAYGIAQASITEQLNGLGGVESQFVKNLLNSVLQVSLDISLPSAQYLKTLVSEVLIQGAPSKLWWERQAANTTFNFSNVVRLGMAQGETIDQIVARVAGKGEQPGIMNVARNNARALVHSSVMTVSNQARLETFKQNPSVVKGNQWLATMDSHTCVLCAARSGLEWDLDGAPIDHDLPFQAPPIHWGDRCVLSPVLKTFAEMGLDIPEIKKSTRASSGGQISADTTFTDFLKSKSDQFQNEMLGTGKADLFRRGKISLSDLLDQRGNELNLAQLRAKYDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYI4</accession>
    <name>A0A2S9GYI4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Spermine/spermidine synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2490</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92760">
        <property type="protein sequence ID" value="PRC92760"/>
        <property type="gene ID" value="S2091_2490"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="259" mass="28773" checksum="641018A1275E965E" modified="2018-07-18" version="1">MPSQSVVYHPSVVILEYQGVRSLCFERDGDGVMALQGAMRMAMPDQIELEYVQQMMMWMLFNDAPKHIVQLGLGSAALTKFCYRRFPAAQISAVELNPKVIAACHEHFKLPPNDARLNVMAMNALEFVLNPANHASRDILQVDLYDAQALEPALGSVEFYQSCANCLSENGMITVNLFCDGDTENSAYADNLQAIQAAFDAVVWLPEVHDANVVALAFKRAPAIDFSVLYERAVDIRSNMKLPAPVWVNGLKEWMGAEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYN7</accession>
    <name>A0A2S9GYN7_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7">Phosphoribosylamine--glycine ligase</fullName>
            <ecNumber evidence="2 7">6.3.4.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">GARS</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Glycinamide ribonucleotide synthetase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Phosphoribosylglycinamide synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">purD</name>
        <name evidence="10" type="ORF">S2091_2553</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>5-phospho-beta-D-ribosylamine + ATP + glycine = ADP + H(+) + N(1)-(5-phospho-beta-D-ribosyl)glycinamide + phosphate</text>
            <dbReference type="Rhea" id="RHEA:17453"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:58681"/>
            <dbReference type="ChEBI" id="CHEBI:143788"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.13"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 7">Purine metabolism; IMP biosynthesis via de novo pathway; N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-alpha-D-ribose 1-diphosphate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the GARS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.13" evidence="2 7"/>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92823">
        <property type="protein sequence ID" value="PRC92823"/>
        <property type="gene ID" value="S2091_2553"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00125"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004637">
        <property type="term" value="F:phosphoribosylamine-glycine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009113">
        <property type="term" value="P:purine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.600.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00138">
        <property type="entry name" value="GARS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020561">
        <property type="entry name" value="PRibGlycinamid_synth_ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000115">
        <property type="entry name" value="PRibGlycinamide_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020560">
        <property type="entry name" value="PRibGlycinamide_synth_C-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037123">
        <property type="entry name" value="PRibGlycinamide_synth_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020562">
        <property type="entry name" value="PRibGlycinamide_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011054">
        <property type="entry name" value="Rudment_hybrid_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43472">
        <property type="entry name" value="PTHR43472"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01071">
        <property type="entry name" value="GARS_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02843">
        <property type="entry name" value="GARS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02844">
        <property type="entry name" value="GARS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01210">
        <property type="entry name" value="GARS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51246">
        <property type="entry name" value="SSF51246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="SSF52440"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00877">
        <property type="entry name" value="purD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 7 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 7" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-grasp" evidence="9">
        <location>
            <begin position="107"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC92823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="424" mass="45302" checksum="E744B1F895154B7D" modified="2018-07-18" version="1">MKILVVGSGGREHALAWKLAQSERIQTVFVAPGNGGTALDSRLKNIDISDPHALAEFAKNEHIGLTLVGPETPLAAGIVNIFRDQGLKIFGPTKEAAQLESSKDFAKSFMQRHGIPTAKHQTFTELAAAHAYIDANGAPIVIKADGLAAGKGVVVAMTLQEAHDAVDMMLSDNKLGDAGARVVIEEFLTGEEASFIVMVDGKNILPLATSQDHKRLCDDDQGPNTGGMGAYSPAPIITPQVHARVMREIIDPTVQGMAKDGIVFTGFLYAGLMIDEHGNPKNLEFNCRMGDPETQPIMARLKTDFVSILEHAVNGHLDTVELEWDRRTALGVVMAAAGYPDAPVKGAHITGVPAETIDCITFHAGTHLDHGNLTVSGGRVLCAVGLGDNVKVAQKHAYDAIDAIQFEGAQARRDIGWRALNKKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYR4</accession>
    <name>A0A2S9GYR4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2581</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92851">
        <property type="protein sequence ID" value="PRC92851"/>
        <property type="gene ID" value="S2091_2581"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01805">
        <property type="entry name" value="ScpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003768">
        <property type="entry name" value="ScpA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33969">
        <property type="entry name" value="PTHR33969"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02616">
        <property type="entry name" value="SMC_ScpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0159">Chromosome partition</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="279" mass="31850" checksum="C2D17AF9530276E5" modified="2018-07-18" version="1">MLDLEKELHQTPNSTPDVVDGIAYAKLYGEPLFKMPTDLYIPPDALEVFLEAFEGPLDLLLYLIRKQNFNILDIPMAQVTRQYLDYVELIRKNNLELAAEYLLMAAMLIEIKSRMLLPVKTGDTGNEADDPRAELVRRLLEYEQIKLAAMDVNAMPQLGRDFLCAQVLVEQNTVLHWPDVEIVDLQSAWADILKRSKLVEHHKISREELSVREHMSGILRRLQSAKFVEFSELFDVSRGAPVLVVNFVALLELAKETLIEITQAEAFAPIYVRLAYSPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYR5</accession>
    <name>A0A2S9GYR5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Sulfate permease and related transporters (MFS superfamily)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_2583</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Membrane</location>
            <topology evidence="1 5">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92853">
        <property type="protein sequence ID" value="PRC92853"/>
        <property type="gene ID" value="S2091_2583"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008271">
        <property type="term" value="F:secondary active sulfate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011547">
        <property type="entry name" value="SLC26A/SulP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001902">
        <property type="entry name" value="SLC26A/SulP_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11814">
        <property type="entry name" value="PTHR11814"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01740">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00916">
        <property type="entry name" value="Sulfate_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SSF52091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50801">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="28"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="55"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="98"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="124"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="178"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="222"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="310"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="350"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="404"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="domain" description="STAS" evidence="6">
        <location>
            <begin position="453"/>
            <end position="556"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC92853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="574" mass="61721" checksum="3C4AD816D1F81B57" modified="2018-07-18" version="1">MSRINLHFRPRLWDELLSYNRNRFTQDLIAGLTVGIVALPLAMAFGIASGVAPEAGIFTAIIAGFLISALGGSRVQIGGPAGAFIIVVYGIIEKYGLANLLIATIFSGIIMMAMGVFKLGSLIRFIPVSIVIGFTNGIAVLIALSQMKDFFGLNIAKMPGDFFAQITVMAEQAHTVNWTALGLASASLLVIFGWPLFLTFIGQHAQHQKHLLAPLKKIPSTVIALVLGTLAVYLFGLNVATIGSKFGGIPQQLPGFSLPTFSWVLVKQLFAPSLTIALLGSIESLLCARVADNLMADDLDHHKHDPNQELMALGVANIVVPFFGGIPSTGTIARTVTNVRSGASSPIAGIVHALTLLLIVLAAAPLAASIPLATLAAILLFVAFNMGEWHEFRKLGHFSMNYRIILLGTFLLTVILDLSVAVEVGLMLACIFFIYRISSVTTVTAIDSQQLPEHVAAFSIFGSLFFGAVDKLEALLKPHQIPPEIVILELHQLINMDTTGLDGLQTLQHTLEKYQSQLLLCGTNSQPLDLMRRGGFIDKIGAENCLFDLNHAIQRAHVLCGTSASKNTQNQRTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYS8</accession>
    <name>A0A2S9GYS8_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Pseudouridine synthase</fullName>
            <ecNumber evidence="3">5.4.99.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_2291</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the pseudouridine synthase RsuA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.-" evidence="3"/>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92874">
        <property type="protein sequence ID" value="PRC92874"/>
        <property type="gene ID" value="S2091_2291"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120159">
        <property type="term" value="F:rRNA pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000455">
        <property type="term" value="P:enzyme-directed rRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1560">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.580">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042092">
        <property type="entry name" value="PsdUridine_s_RsuA/RluB/E/F_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006145">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000748">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluB/E/F"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018496">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020094">
        <property type="entry name" value="TruA/RsuA/RluB/E/F_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00849">
        <property type="entry name" value="PseudoU_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01479">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00363">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00093">
        <property type="entry name" value="TIGR00093"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01149">
        <property type="entry name" value="PSI_RSU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S4" evidence="5">
        <location>
            <begin position="168"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="413"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="11"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="75"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="107"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC92874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="509" mass="55354" checksum="E3606566E3975E1F" modified="2018-07-18" version="1">MIMMSTKNPDDAMPAENNTENTAPTASDKPREKKHGVRGPRMMRRARNERAETAVESAAGAATDAMPSTEGAEKSDAGARVERAPRQHAKPAGRSDARPAKFDSANKSRAGQRSHSRPTPSQGAQAPDDVFSFVTSEAFDQAHADVKPVGRGAAKPVRRDLTSDDDAPKLHKVLAEAGLGSRRDMEELIVAGRVSVNGEPAHIGQRILPTDFVRLNGKIIQRKISTKPPRILVYHKPAGQIVSTNDPEGRESVFSSLPTMKTGKWLAVGRLDFNTEGLLLFTTSGDLANRLMHPRYGIEREYAVRTLGTLEEGMRQKLLSGVELEDGLAQFSKISDGGGDGVNKWYRVVIGEGRNREVRRMFEAIGLTVSRLIRTRYGVMTLPSNLKRGRWEELEENAARELLKLCGMEKEAKIGRDDRGGSSKPAKSGPNGRFAGNSGNVANTDRAPRFAKPQDKFSAAPGKPQRSRQPDPMQTALGFPAAAPRKPRAGVAGATPHTYQGIPRKRARG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZB8</accession>
    <name>A0A2S9GZB8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2160</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93074">
        <property type="protein sequence ID" value="PRC93074"/>
        <property type="gene ID" value="S2091_2160"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="141" mass="15940" checksum="32A07CEF10DDA907" modified="2018-07-18" version="1">MKLNLRADSVAHQVLMMLVSEPKGCLHVSAFFDLLKGKSSTTHGTRIINRCGRIISERMATVKAEMWTITERGRRQLVEPDSMDFDVSNPTLITPSRTIRPFRPLQLKQNKQPYRAGSNDYSLIPSLFGDVRKLPNGEVVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZD4</accession>
    <name>A0A2S9GZD4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2185</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93099">
        <property type="protein sequence ID" value="PRC93099"/>
        <property type="gene ID" value="S2091_2185"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="142" mass="15645" checksum="20CA72177C386798" modified="2018-07-18" version="1">MEKIFILFWVTLLSACSTTQTLQSEAKQVKSENIYAYQMKSSVADAHIFVTRDSGIYGIACTTSLLINGKLVAKFEAGERAEFYLPSGEYILAHGVASKGLCRLGKDSGGHGRETFLRSGETKWFRLYLEGDNGDIAPIIPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZH8</accession>
    <name>A0A2S9GZH8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">40-residue YVTN family beta-propeller repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2217</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93131">
        <property type="protein sequence ID" value="PRC93131"/>
        <property type="gene ID" value="S2091_2217"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011048">
        <property type="entry name" value="Haem_d1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019405">
        <property type="entry name" value="Lactonase_7-beta_prop"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011964">
        <property type="entry name" value="YVTN_b-propeller_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10282">
        <property type="entry name" value="Lactonase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51004">
        <property type="entry name" value="SSF51004"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02276">
        <property type="entry name" value="beta_rpt_yvtn"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015522769" evidence="1">
        <location>
            <begin position="27"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="329" mass="35079" checksum="E4D18B3B64425AC1" modified="2018-07-18" version="1">MNALKRIFSILGIFVATLASVGVTSAAEPRWTFDGAIHNNSLAISPDETIAVASYSERPDVVVYDLNSGKVRAVLHGYVTPRNIVFDPSGKSFYVSDSSLGQIKKIDTASLQELATLPAGAGAFGTTISRDGQTLYVNNEAASTVTNFDLTTNRPKAVITGFAQPRQGVRLNSSGDTLFVTNFLGDKITLVDTQSNKIVAEITGFNKIRAISITHDGKQLFAANSGSNSIAVVDIAKRQIIATIPVGKDPYGAALTPDEHSLYSGNLADNTLSVISLASQTVTATVNGFKQPRQAIVFTHDSKFAYVLNEDLSIVKLDLASNQVVETLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZJ6</accession>
    <name>A0A2S9GZJ6_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Tryptophan synthase alpha chain</fullName>
            <ecNumber evidence="7">4.2.1.20</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">trpA</name>
        <name evidence="9" type="ORF">S2091_2245</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate + L-serine = D-glyceraldehyde 3-phosphate + H2O + L-tryptophan</text>
            <dbReference type="Rhea" id="RHEA:10532"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:57912"/>
            <dbReference type="ChEBI" id="CHEBI:58866"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="4.2.1.20"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 5/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Tetramer of two alpha and two beta chains.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7 8">Belongs to the TrpA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.20" evidence="7"/>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93159">
        <property type="protein sequence ID" value="PRC93159"/>
        <property type="gene ID" value="S2091_2245"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00035">
        <property type="reaction ID" value="UER00044"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004834">
        <property type="term" value="F:tryptophan synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04724">
        <property type="entry name" value="Tryptophan_synthase_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00131">
        <property type="entry name" value="Trp_synth_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018204">
        <property type="entry name" value="Trp_synthase_alpha_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002028">
        <property type="entry name" value="Trp_synthase_suA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43406">
        <property type="entry name" value="PTHR43406"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00290">
        <property type="entry name" value="Trp_syntA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="SSF51366"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00262">
        <property type="entry name" value="trpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00167">
        <property type="entry name" value="TRP_SYNTHASE_ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5 7" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="6 7" id="KW-0456">Lyase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0822">Tryptophan biosynthesis</keyword>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="49"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00131"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC93159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="269" mass="28872" checksum="6E550A19D106DFCA" modified="2018-07-18" version="1">MSRIKNTFAELAKNGRKGLIPFITAGDPSPAITVQLMHALVRGGADIIELGVPFSDPMADGPVIQRASERALKHGVGLIDVLQCVREFRASNKITPVVLMGYANPIERMGIELFVSESANAGVDGVLVVDYPPEECVAYAACMKKHGLDVIFLLAPTSTDQRIAQVAQIASGYVYYVSLKGVTGNNAIDLSEVNRMLPKIKQHVQVPVAVGFGVRDAATAKLISHVADAVVIGSRIIQEIETHDANLAPDLMLTSVQDFLSTVRQAMNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZK4</accession>
    <name>A0A2S9GZK4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="12">ABC transporter, permease/ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">S2091_2132</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93046">
        <property type="protein sequence ID" value="PRC93046"/>
        <property type="gene ID" value="S2091_2132"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011918">
        <property type="entry name" value="ABC_MsbA_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="SSF90123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02204">
        <property type="entry name" value="MsbA_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 8 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-1278">Translocase</keyword>
    <keyword evidence="2 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="24"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="65"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="143"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="166"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="248"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="285"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="11">
        <location>
            <begin position="26"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="345"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="380"/>
            <end position="387"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PRC93046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="588" mass="63053" checksum="5B31557BCCD1AFAC" modified="2018-07-18" version="1">MKAPSSINTLKGLLPFLRPYLKQFYLAGLALLVAASATLAIPYAFRQMIDMGFSGQGSISHVDAAFLALFGVACVLAIATAARFYMVSLLGERVTADIRTAVYEHVIEQSPEFFETTRSGEVLSRLTTDTTLIQAMVGTSISMALRNTLLFLGGLVMLFITSPKLSSIIIVALALVVLPIVLFGRRVRTLSRDSQDRIADASALAGEILNAMPIVQAYTQEPHEAARFKLSVENAFATAMRRIRARSLLTVVAILLVFGAIVFVLWLGAHAVMDKRMTGGELSQFILYATIVAGAVGALSEVMGDAQRAAGATERLLELLAAKSSISEPAQPVALPPRSSNGATLTLKDIGFHYPSRPNTAALSHLSIQVAAGETVAVVGSSGAGKTTLFQLLLRFYDPQQGQINLDGINIRDLSLHTLRDTIGIVPQDTVIFSANAMENIRYGRSGASDAEVINAAKMAAAHEFIEKLPDGYQSFLGERGVRLSGGQRQRISIARALLKNPALLLLDEATSALDAESERLVQGALVTAMQGRTTLIIAHRLATVQRADRILVMEHGHIVETGTHNSLVAEGGIYAKLAALQFQTFES</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZW7</accession>
    <name>A0A2S9GZW7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2017</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93279">
        <property type="protein sequence ID" value="PRC93279"/>
        <property type="gene ID" value="S2091_2017"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="382" mass="43199" checksum="7D007168D1CC2172" modified="2018-07-18" version="1">MQPFFHDGDKNICGDGNLYLGFDGVFAGSQKGFDTQMLFDPFEEQFDLPALLVQRGDQFRFERKIVGQEYEAFSVLVFDDNAPQRPWIILACVIQRQLASLVANEIGAGSIDRVGVTALEFGVALGSGYKESVQLVETMQPFEIQVAAIHQIKCTWLDSQIVQNIDFVGLAVGDMNKGRDRTTQVEQSMQFDCSFGGAKRRPWMNRQTQIDCGCIEGIHSGVQIDSHRFVGIQRSSHRNQMLRKIGINLPRTSGIRIRQRVARNGFASKSHVVKPVRLRPQIDFDVAQGFSVGQLSECHSEELIQTRKILDHVFAPVRRNASTKRGQWQISHDLRKNEFAMMHSSVERKSAKSTYFAPRRSNRDQTNSSFYASKSLTYKLLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H073</accession>
    <name>A0A2S9H073_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cyd operon protein YbgT</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1769</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93382">
        <property type="protein sequence ID" value="PRC93382"/>
        <property type="gene ID" value="S2091_1769"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011724">
        <property type="entry name" value="Cyd_oper_YbgT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012994">
        <property type="entry name" value="YbgT_YccB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08173">
        <property type="entry name" value="YbgT_YccB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02106">
        <property type="entry name" value="cyd_oper_ybgT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="54" mass="6231" checksum="EEF666865C80AF72" modified="2018-07-18" version="1">MWYFSWILGLGLAVAFGIINVMWLEADYAFGARDEDTTRERFEAAQQQATLKND</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H091</accession>
    <name>A0A2S9H091_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Biopolymer transport protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_1774</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the ExbD/TolR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93387">
        <property type="protein sequence ID" value="PRC93387"/>
        <property type="gene ID" value="S2091_1774"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003400">
        <property type="entry name" value="ExbD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30558">
        <property type="entry name" value="PTHR30558"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02472">
        <property type="entry name" value="ExbD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="28"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC93387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="143" mass="15815" checksum="1D2D7813152F415B" modified="2018-07-18" version="1">MAMAIGSPDGDGEDEVNSTINTTPLVDVMLVLLIIFLITVPVVTHTIPVKLPSERNQLFKTHIEDIDLSVNKDGEIFWGQKQLADNNELLEKLKKVSVLVPQPEVHIRGDQNARYEFVGKVILTAQRAGIAKVGFVLEPPARH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0A4</accession>
    <name>A0A2S9H0A4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="10">MotA/TolQ/ExbB proton channel family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">S2091_1775</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Membrane</location>
            <topology evidence="1 6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the exbB/tolQ family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93388">
        <property type="protein sequence ID" value="PRC93388"/>
        <property type="gene ID" value="S2091_1775"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002898">
        <property type="entry name" value="MotA_ExbB_proton_chnl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01618">
        <property type="entry name" value="MotA_ExbB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5016296481" evidence="8">
        <location>
            <begin position="27"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="91"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="198"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="245"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="domain" description="MotA_ExbB" evidence="9">
        <location>
            <begin position="173"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC93388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="307" mass="31776" checksum="BF2E44780E4D4C48" modified="2018-07-18" version="1">MKNRVSLSLSALIAAIALSASAVSFAADTPAAAAAPADTPAAAAPAAATPAVATPAPDAAAPAAAAATPEATNESVDNPYGLEALWKGGDFISRGTLIILSIMSMGSWYILITKMIDQYKMSGQASDAKKSFWKAASVPAGITSLKESSPFRFIAEIGSKASEHHEGSLLEKIDLNEWVTMSIQRAVEKVQSRLQDGLAFLATVGSTAPFVGLFGTVWGIYNALIKIGIAGQASIDKVAGPVGEALIMTAFGLFVAVPAVLGYNFLVRRNKSAMEEVRAFSADLHLVLISGAMSTSEVGRTNMKKAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0D1</accession>
    <name>A0A2S9H0D1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93413">
        <property type="protein sequence ID" value="PRC93413"/>
        <property type="gene ID" value="S2091_1800"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="297" mass="32647" checksum="CBAE545706382984" modified="2018-07-18" version="1">MTLDQLRIFIQVAEREHLTQAADVLALTPSAVSSSIKSLENQYGTVLFNRVGRRIELTEAGRIFLTEAKSTLNSARAAELTLKELGSMKRGTLNIHASQTIASYWLPPILVRFHQKHPQISINLIVGNTQQVAQSVHDGTADLGYVEGRVDDTLLNVCTVYEDQVVVVVAPEHPWGNGALINPTELVKADWIMREPGSGTRAVLENILALVGVEISNLNVALTLPSNEAVRSAVISGQFATLVSKFVVDAHIKAGLLRIVNIALPHREFYSLTHKARYKTKASLAFEEVVRLQVIME</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0J9</accession>
    <name>A0A2S9H0J9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1884</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93497">
        <property type="protein sequence ID" value="PRC93497"/>
        <property type="gene ID" value="S2091_1884"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009915">
        <property type="entry name" value="NnrU_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07298">
        <property type="entry name" value="NnrU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="71"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="113"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="164"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="domain" description="NnrU" evidence="2">
        <location>
            <begin position="3"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="192" mass="21335" checksum="2F6CB2A1F7258924" modified="2018-07-18" version="1">MLILVSGLFLFFGVHSIRLFADGWRARQIERIGAMPWKGIYSVVSIIGFGLIIWGFGLARSTPIILWVPPTWTRHLTAGLMLISFLLLVATYVPGNRIKAIIGHPMLLAVKVWAAAHLLANGTLADTILFGAFLIWSITNFAVSRRRDRLSGVIYPVIGIWRDLMVICIGLIAFVLFAHFGHVWLIGVNPFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0N5</accession>
    <name>A0A2S9H0N5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1926</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93539">
        <property type="protein sequence ID" value="PRC93539"/>
        <property type="gene ID" value="S2091_1926"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="54" mass="5590" checksum="ED9BB9D02670411E" modified="2018-07-18" version="1">MLMSAADVAFMKGEAAARPGDGPDMALVRASEYGYIVPGAQRTAFVQGFLLAIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0Q8</accession>
    <name>A0A2S9H0Q8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glycosyl transferase family 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_1562</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93561">
        <property type="protein sequence ID" value="PRC93561"/>
        <property type="gene ID" value="S2091_1562"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="228"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="265"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_trans_2-like" evidence="3">
        <location>
            <begin position="4"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC93561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="309" mass="35265" checksum="74E1CD505CED0CF8" modified="2018-07-18" version="1">MKLSIVTTLYQSASYINEFHRRVSAVANQLVEENYEIILVNDGSPDNSLELALHLTKNDSHVVVIDLSRNFGHHKAMMTGLAHAKGELVLLIDSDLEEEPEYLITFADKMLKEGCDVVYGVQEKRKGNWFERRSGQLFYRFFKALTGLALPENIVTARLMTRRYVAALLQHKEREVFMAGLWHITGFEQRPHLVKKHSCSETTYTFRRKMSLLVNSVTSFSNAPLVGIFYIGVSISLVAFFYTCYLAIQWAFLAKPLSGWTSVMASIWLLGGMIISFIGVVGIYLSKIFSETKQRPYTIIRQIYAKQKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0V2</accession>
    <name>A0A2S9H0V2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NAD/NADP transhydrogenase alpha subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1613</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93612">
        <property type="protein sequence ID" value="PRC93612"/>
        <property type="gene ID" value="S2091_1613"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007886">
        <property type="entry name" value="AlaDH/PNT_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007698">
        <property type="entry name" value="AlaDH/PNT_NAD(H)-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01262">
        <property type="entry name" value="AlaDh_PNT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05222">
        <property type="entry name" value="AlaDh_PNT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01002">
        <property type="entry name" value="AlaDh_PNT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01003">
        <property type="entry name" value="AlaDh_PNT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AlaDh_PNT_N" evidence="2">
        <location>
            <begin position="4"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="domain" description="AlaDh_PNT_C" evidence="1">
        <location>
            <begin position="145"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="371" mass="38848" checksum="EFD15B42C0F1178E" modified="2018-07-18" version="1">MKIGIPAETKSGETRVAATPETIKKYLAAKHQVLVQAGAGIASSIPDEAYVAAGAQIVNAADAFGCELVLKVRAPDSAERALMKSGSVLVGMLNPFDTENTAAMAACGIHAFALEAAPRITRAQAMDVLSSQANIAGYKAVMLAANTYGRFMPMLMTAAGTVKAARVLIMGVGVAGLQAIATAKRLGAVIEASDVRPPVKEQVESLGAKFIDVPFITDEEKEIAQGVGGYARSMPADWMRRQAELVHERAKLADIIITTALIPGRKAPILISEETVKAMKPGSVIVDMAVEQGGNCPLSECGTTVTKYGVHIIGVPNLATLVPADASALYARNVLDFLKLIIDKDAALAINREDEIVVATLICSGGEVLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H109</accession>
    <name>A0A2S9H109_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Short-chain dehydrogenase of various substrate specificity</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1673</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93672">
        <property type="protein sequence ID" value="PRC93672"/>
        <property type="gene ID" value="S2091_1673"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="241" mass="26878" checksum="3CEEB26F378EEA00" modified="2018-07-18" version="1">MNIMIIGGTSGIGWALAEHYLRDGHNVMVCGRDLQRLTSDHHYPMLSCTQLDIADNVALAKAIEVFAEESLDLLIVSAGFYFNDRHQTLDAATTLRMLQTNVSGLNTAFELAAEHMLSKKNGHLVAISSVAGLLKDYPGASLYSACKRSVLSLCETYRIALAPFSIAVTAIVPGYVDTEKLRQLNDGDASHKPFILTEEKAVEYIVDAIHRRLAISIFPWQMRWLIKLFNYLPSQLLRLRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H141</accession>
    <name>A0A2S9H141_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative amidophosphoribosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1705</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93704">
        <property type="protein sequence ID" value="PRC93704"/>
        <property type="gene ID" value="S2091_1705"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRibTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00156">
        <property type="entry name" value="Pribosyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pribosyltran" evidence="1">
        <location>
            <begin position="145"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="244" mass="26869" checksum="64035BF4803EB606" modified="2018-07-18" version="1">MLRKLLHANVRSLKSTVAAGIAKLIPSTCLLCGLENEHIICCACSAQFFSGNPKRCISCALPILKHDTHCGACLKKPPAFDHTTVACDYVAPLDQLILALKFGHRLAIAPALAELLANAVHDIPELLIAVPLSRERLAQRGFNQALEIAKPLAHKLQRPIYPRLLLRVRDTEAQTLLHPDQRHENIRYAFSPNDGYADKIRGRHIGVVDDVMTTGSTLQEIAACLKRHGAKRVSNIVFARTPPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H142</accession>
    <name>A0A2S9H142_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1664</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93663">
        <property type="protein sequence ID" value="PRC93663"/>
        <property type="gene ID" value="S2091_1664"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="93"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="142"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="187"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="221"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="260" mass="29002" checksum="93E04DA55F1A6CD9" modified="2018-07-18" version="1">MNKLPANTGWLWVKQGYQYFKQQPMEFSLLFLSYLFSVLILGFIPFLGQLLAFIFLPLFTLSFMQACREIDQGARVHPRLLLFGFRSPQVVKLLQLGMLYLIAAVTALGASTLIDDGVLWQVVTGQMELTAKNVEGTNMSAAMLFAMLIYIPALLAFWFAGPLIAWQQMPLFKAIFYSFIASVRAARAFFVYGIAWFAVGGILPTICSVLIAAIIGNPNMIFMIVMPLSMVLTIILYCSFYPSYKSIFGQADAIESSTIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H169</accession>
    <name>A0A2S9H169_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">WHG domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_1733</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93732">
        <property type="protein sequence ID" value="PRC93732"/>
        <property type="gene ID" value="S2091_1733"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025996">
        <property type="entry name" value="TetR_C_WHG"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13305">
        <property type="entry name" value="TetR_C_33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="5">
        <location>
            <begin position="29"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="4">
        <location>
            <begin position="52"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC93732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="224" mass="25010" checksum="10C57C18831F7BBE" modified="2018-07-18" version="1">MNATKNKLINPKVTPDPVDFKQEQQVLRSTIRQAMLAAANQLLSEEGLPGFTLRRVADAVNCSTTLLYSQFGGKDGLSNELYLEGFSRLKQEFAQQELGDLLGMERLWRYANSYRAFAHHNPSYYVIMFGDGLVGFVPPPESRQIAWEAFSVLIAHFASCMEQGLMPAASPNSAARLLWAAMHGVINLELKGYYLTQQQADHLYDAAVRAVLFSLQHPVEATLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1I3</accession>
    <name>A0A2S9H1I3_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Protein MgtC</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_1727</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell inner membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the MgtC/SapB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93726">
        <property type="protein sequence ID" value="PRC93726"/>
        <property type="gene ID" value="S2091_1727"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003416">
        <property type="entry name" value="MgtC/SapB/SrpB/YhiD_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33778">
        <property type="entry name" value="PTHR33778"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02308">
        <property type="entry name" value="MgtC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01837">
        <property type="entry name" value="MGTCSAPBPROT"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="51"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="89"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="112"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC93726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="248" mass="26568" checksum="DCE90DF2C6BD9772" modified="2018-07-18" version="1">MRLMDIFLSYWSYEHLQANFVIGLNLLGALVLGLVLGYERTYHGRAAGMRTYGLVCMVSAGIVIISGYPELWFGSQMANANFHADPTRSIQGIVTGIGFLCAGVIMKDGYSISGLTTAASLWTVSAVGIMVGIGLYAAAIFFALGAVVCMTLVSRLEAHLPSRPAVAVVLKFKKDFLPNLAGLKAAVNNRGYSLAQGSISISHQQGCVEWHFVVLATDRILGATLPNLAIELQAVDGVEDLYISHARN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1N1</accession>
    <name>A0A2S9H1N1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Type III secretion protein, YscU/HrpY family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">S2091_1476</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the type III secretion exporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93867">
        <property type="protein sequence ID" value="PRC93867"/>
        <property type="gene ID" value="S2091_1476"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1690.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006307">
        <property type="entry name" value="BsaZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006135">
        <property type="entry name" value="T3SS_substrate_exporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029025">
        <property type="entry name" value="T3SS_substrate_exporter_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30531">
        <property type="entry name" value="PTHR30531"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01312">
        <property type="entry name" value="Bac_export_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00950">
        <property type="entry name" value="TYPE3IMSPROT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160544">
        <property type="entry name" value="SSF160544"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01404">
        <property type="entry name" value="FlhB_rel_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="29"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="74"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="135"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="174"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="199"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC93867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="364" mass="40902" checksum="D84F7D7D30295392" modified="2018-07-18" version="1">MSESKTEKATPKKRRDAAKRGQSFKARDLVVACLMFSGVLLVVWLGTLAEIGAAFVGAVRSGFTLDLHRYAADILLLALKVVGPIILLSIVATAFPSLLQSGFSLASEAFKINFGALNPIKGFKKIFNLRTVKEFVKAVLYLCCFSAAFMLMWWSQRKLIFSQVHASIPEIIGIWGKLIISLVLICLGCIAAVLVLDALAELFLYLKELRMEKQEVKREYKELEGDPLMKSKRKQVHMEMLSEQEKHDIENSRMVIANPTHVAIGIYFKPELSPIPFISIRESNQRALAVRNYAEKVGVPVIVDIGLARRLYRTHRRYAMVSMEEIQPVVRLLLWLQQVEIAGIEIDVDTNPENDNNDAAKDSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1X8</accession>
    <name>A0A2S9H1X8_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Ubiquinol-cytochrome c reductase iron-sulfur subunit</fullName>
            <ecNumber evidence="10">7.1.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">S2091_1164</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>a quinol + 2 Fe(III)-[cytochrome c](out) = a quinone + 2 Fe(II)-[cytochrome c](out) + 2 H(+)(out)</text>
            <dbReference type="Rhea" id="RHEA:11484"/>
            <dbReference type="Rhea" id="RHEA-COMP:10350"/>
            <dbReference type="Rhea" id="RHEA-COMP:14399"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="EC" id="7.1.1.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>2Fe-2S cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49601"/>
        </cofactor>
        <text evidence="10">Binds 1 [2Fe-2S] cluster per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="10">The Rieske protein is a high potential 2Fe-2S protein.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.1.1.8" evidence="10"/>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC93991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93991">
        <property type="protein sequence ID" value="PRC93991"/>
        <property type="gene ID" value="S2091_1164"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008121">
        <property type="term" value="F:ubiquinol-cytochrome-c reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.102.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017941">
        <property type="entry name" value="Rieske_2Fe-2S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036922">
        <property type="entry name" value="Rieske_2Fe-2S_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014349">
        <property type="entry name" value="Rieske_Fe-S_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005805">
        <property type="entry name" value="Rieske_Fe-S_prot_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006317">
        <property type="entry name" value="Ubiquinol_cyt_c_Rdtase_Fe-S-su"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10134">
        <property type="entry name" value="PTHR10134"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00355">
        <property type="entry name" value="Rieske"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00162">
        <property type="entry name" value="RIESKE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50022">
        <property type="entry name" value="SSF50022"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01416">
        <property type="entry name" value="Rieske_proteo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51296">
        <property type="entry name" value="RIESKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="9" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="10" id="KW-0249">Electron transport</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="31"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="domain" description="Rieske" evidence="12">
        <location>
            <begin position="104"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PRC93991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="221" mass="23524" checksum="9D96278E41432D46" modified="2018-07-18" version="1">MMAVNFSTNLVLTNGVGMGNEKQVDSGRRGLLVATCAAGGVVGLAATGALVSTFQPSERAKAAGAPVEVDISSLQPGEMTVAEWRGKPVWILKRTPEMMASLAKTESEVADPDSLKPYTMPLPEYCEKQSRSRKDHKDVLIAVGICSHLGCSPGKKFAEGPQPSLPDNWVGGFLCPCHGSTFDLSGRVFKNKPAPQNLDVPPHMYLSDTKIVIGKDEKGEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H234</accession>
    <name>A0A2S9H234_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HTH cro/C1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1217</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94044">
        <property type="protein sequence ID" value="PRC94044"/>
        <property type="gene ID" value="S2091_1217"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="20"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="113" mass="13125" checksum="4CAFBC9CA04DF3DB" modified="2018-07-18" version="1">MTDLAAPFAPDWVSPPGDTLLDILEERDWTQDELAQRLGYTAKHVNQLIKDKVPLTEDAAIRLERVVGSTVGFWLAREAKYRERCVRLQAAEKFAGWIRYQLEKCWRNCKIPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2D5</accession>
    <name>A0A2S9H2D5_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5 7">50S ribosomal protein L3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rplC</name>
        <name evidence="9" type="ORF">S2091_1315</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 7">One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5 7">Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.</text>
    </comment>
    <comment type="PTM">
        <text evidence="5">Methylated by PrmB.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the universal ribosomal protein uL3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94142">
        <property type="protein sequence ID" value="PRC94142"/>
        <property type="gene ID" value="S2091_1315"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01325_B">
        <property type="entry name" value="Ribosomal_L3_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000597">
        <property type="entry name" value="Ribosomal_L3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019927">
        <property type="entry name" value="Ribosomal_L3_bac/org-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019926">
        <property type="entry name" value="Ribosomal_L3_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11229">
        <property type="entry name" value="PTHR11229"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00297">
        <property type="entry name" value="Ribosomal_L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03625">
        <property type="entry name" value="L3_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00474">
        <property type="entry name" value="RIBOSOMAL_L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0488">Methylation</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5 7" id="KW-0699">rRNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="130"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="modified residue" description="N5-methylglutamine" evidence="5">
        <location>
            <position position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00019301"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC94142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="218" mass="22946" checksum="41537D89D5926D16" modified="2018-07-18" version="1">MSLGLVGRKVGMMRIYTDDGDSIPVTVLDVSNNRVTQIKTPETDGYTAVQVTFGQRRASRVTKAVAGHLAKAGVEAGTVLKEFRIDAAKAAELKAGDVVPVGMFEAGQIVDVQGVTIGKGYAGTIKRHHFSSGRASHGNSRSHNVPGSIGMAQDPGRVFPGKRMTGHLGDVTRTVQNLEIARIDTVRQLLLVKGAVPGAKNGQVVVTPAIKVKTKKGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2I4</accession>
    <name>A0A2S9H2I4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1249</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94076">
        <property type="protein sequence ID" value="PRC94076"/>
        <property type="gene ID" value="S2091_1249"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="46" mass="4806" checksum="FCD7B3ED09E1CBAA" modified="2018-07-18" version="1">MDKEQTLEISVTGHLIVNDANLALTAALNGAGISFILRAPSNEEPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2N5</accession>
    <name>A0A2S9H2N5_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">50S ribosomal protein L18</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rplR</name>
        <name evidence="8" type="ORF">S2091_1299</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the universal ribosomal protein uL18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94126">
        <property type="protein sequence ID" value="PRC94126"/>
        <property type="gene ID" value="S2091_1299"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01337_B">
        <property type="entry name" value="Ribosomal_L18_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005484">
        <property type="entry name" value="Ribosomal_L18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004389">
        <property type="entry name" value="Ribosomal_L18_bac-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12899">
        <property type="entry name" value="PTHR12899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00861">
        <property type="entry name" value="Ribosomal_L18p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00060">
        <property type="entry name" value="L18_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 7 8" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 7" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC94126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="120" mass="12849" checksum="DCD7376CD6F335BE" modified="2018-07-18" version="1">MDKKQSRLRRARQTRAKIAELKVNRLAVHRTNLHIYANIIGPDAKILASASTLEASVRAELAAASGNGGNVAAATLVGKRVAEQALKAGVTEVAFDRSGFRYHGRIKALAEAAREAGLKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H395</accession>
    <name>A0A2S9H395_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein-export protein SecB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">secB</name>
        <name evidence="4" type="ORF">S2091_1075</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the SecB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94454">
        <property type="protein sequence ID" value="PRC94454"/>
        <property type="gene ID" value="S2091_1075"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051262">
        <property type="term" value="P:protein tetramerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00821">
        <property type="entry name" value="SecB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003708">
        <property type="entry name" value="SecB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035958">
        <property type="entry name" value="SecB-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36918">
        <property type="entry name" value="PTHR36918"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02556">
        <property type="entry name" value="SecB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01594">
        <property type="entry name" value="SECBCHAPRONE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54611">
        <property type="entry name" value="SSF54611"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00809">
        <property type="entry name" value="secB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0653">Protein transport</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0811">Translocation</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC94454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="163" mass="17738" checksum="8D6D2EA153282B63" modified="2018-07-18" version="1">MSEENLQPVFQIQRVYLKDLSLEQPNSPAIFLEQEAPAIEVAVDVAAQPLADGIYESTVTVTVTAKIKDKVAFLVEGKQAGIFEVRNVPENQLAPLLGIGCPNIVYPYLRSNIADAITRAGFPPVHLSEINFEMFFQQRMQAAAAAAEQAQAAGTEEVAQVTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3C0</accession>
    <name>A0A2S9H3C0_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 6">2,3-bisphosphoglycerate-dependent phosphoglycerate mutase</fullName>
            <shortName evidence="5">BPG-dependent PGAM</shortName>
            <shortName evidence="5">PGAM</shortName>
            <shortName evidence="5">Phosphoglyceromutase</shortName>
            <shortName evidence="5">dPGM</shortName>
            <ecNumber evidence="5 6">5.4.2.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">gpmA</name>
        <name evidence="7" type="ORF">S2091_1078</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 6">Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>(2R)-2-phosphoglycerate = (2R)-3-phosphoglycerate</text>
            <dbReference type="Rhea" id="RHEA:15901"/>
            <dbReference type="ChEBI" id="CHEBI:58272"/>
            <dbReference type="ChEBI" id="CHEBI:58289"/>
            <dbReference type="EC" id="5.4.2.11"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5 6">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 3/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.2.11" evidence="5 6"/>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94457">
        <property type="protein sequence ID" value="PRC94457"/>
        <property type="gene ID" value="S2091_1078"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00186"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046538">
        <property type="term" value="F:2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01039">
        <property type="entry name" value="PGAM_GpmA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001345">
        <property type="entry name" value="PG/BPGM_mutase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005952">
        <property type="entry name" value="Phosphogly_mut1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11931">
        <property type="entry name" value="PTHR11931"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="SSF53254"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01258">
        <property type="entry name" value="pgm_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00175">
        <property type="entry name" value="PG_MUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0312">Gluconeogenesis</keyword>
    <keyword evidence="3 5" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="4 5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="8"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="21"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="87"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="114"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="183"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="active site" description="Tele-phosphohistidine intermediate" evidence="5">
        <location>
            <position position="9"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="5">
        <location>
            <position position="87"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="60"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="98"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="5">
        <location>
            <position position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC94457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="248" mass="27958" checksum="B57D2749F4D5BBCE" modified="2018-07-18" version="1">MYKLVLMRHGESTWNLANRFTGWTDVDLTEKGVAEARAAGELLKQSGFDFDIAYTSVLKRAVRTLWNTLDTMDLMWLPVQHDWRLNERHYGALQGLNKAETAAQYGEDQVMIWRRSYDIPPLPLAQDDPRTDFNNPRYAQLDPKQIPLTECLKDTVERVLPVWNDSIAPAIKSGKRVLISAHGNSLRALIKMLDGVSDQDIVGLNVPNGQPLVYELDADLKPIRHYYLGDQDAINAAMAAVANQGRAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3E9</accession>
    <name>A0A2S9H3E9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_0490</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94487">
        <property type="protein sequence ID" value="PRC94487"/>
        <property type="gene ID" value="S2091_0490"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097367">
        <property type="term" value="F:carbohydrate derivative binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05013">
        <property type="entry name" value="SIS_RpiR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000281">
        <property type="entry name" value="HTH_RpiR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035472">
        <property type="entry name" value="RpiR-like_SIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001347">
        <property type="entry name" value="SIS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046348">
        <property type="entry name" value="SIS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01418">
        <property type="entry name" value="HTH_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01380">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53697">
        <property type="entry name" value="SSF53697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51071">
        <property type="entry name" value="HTH_RPIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51464">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="1" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HTH rpiR-type" evidence="4">
        <location>
            <begin position="16"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="domain" description="SIS" evidence="5">
        <location>
            <begin position="136"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="15"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC94487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="295" mass="31846" checksum="BCAC32BD2CB29AE6" modified="2018-07-18" version="1">MSLISLPISPIATPEKGLLARIRSATTELSRAERQVAEFLLQKPHDIVSMPIRVLAQACQVSEPTVVRFSLSMGFDGYKAFKLAFAKSLATGIPYLHLDVNQADSVRDVLPKVFDRTIAALMEARNSANTATFEAAVQLLASAKRIECYGLGYSGALAIDAQLKFFRFGIPTTVFCDAHLQAQSATLLNKDCVVVAFSRTGRTRDMIRSVQLAKNAGAKILVLCASGGPLAELADVHLSVDVEEDPDIYTPMTSRLAHLTYIDALAVAVTLVRGPAAIAMLERAKASISELRLDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3F8</accession>
    <name>A0A2S9H3F8_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">MvaI_BcnI domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1017</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94396">
        <property type="protein sequence ID" value="PRC94396"/>
        <property type="gene ID" value="S2091_1017"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.210.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029127">
        <property type="entry name" value="MvaI_BcnI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043004">
        <property type="entry name" value="MvaI_BcnI_cat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15515">
        <property type="entry name" value="MvaI_BcnI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MvaI_BcnI" evidence="1">
        <location>
            <begin position="203"/>
            <end position="455"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF15515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="465" mass="52005" checksum="FDFAAF6AFBDBC2A7" modified="2018-07-18" version="1">MAAVQGTYDTQSSKQITMSNITRIFHDLGVVNIYVKKLASNDNSKNQPFFGSHLTDLSFLPTGEMIASNSESQKTLDPKRKIKYQTNLKLSWVDAEGKTYAAPNSKLIYYPQYPEVRFSGFLSGSKADISKWMAPEKQGRSEGRWLLLGVSKDNSIYAYLATPESDLSKELANANYIKISTIFWQLNTSHIATIKSTKEALKTKLLEIHNMGWVASQKLSSEMVMESYKAANGGGYTLEALLGISPNGIAEPDYLGWEVKQFGVTKFPRTGSKPTTLMTPEPNGGFYTEHGAMEFVRTFGYPDKSGKEDRINFGGKHIVDQYQNLTGLTLHLNGYDPALSKITDANGVIALLDKAGNVSASWSFAKLMDHWKRKHSQAVYIPCLRRSDSGTFQYSYGKDIELGEGTNFEKFLVAMHKGDVYYDPGIKLEMATGNSPKLKRRSQFRVNHKDIGALYKKFELIDLCE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3I8</accession>
    <name>A0A2S9H3I8_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">UPF0145 protein S2091_0548</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0548</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the UPF0145 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94545">
        <property type="protein sequence ID" value="PRC94545"/>
        <property type="gene ID" value="S2091_0548"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00338">
        <property type="entry name" value="UPF0145"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002765">
        <property type="entry name" value="UPF0145"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035439">
        <property type="entry name" value="UPF0145_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34068">
        <property type="entry name" value="PTHR34068"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01906">
        <property type="entry name" value="YbjQ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117782">
        <property type="entry name" value="SSF117782"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00338"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="108" mass="11729" checksum="2FC9D44C58A3731D" modified="2018-07-18" version="1">MLITTTENIAGYRVLEAKGQVFGVVVRSRGLAGNLMAGLRSIFGGEITEYTSLLEEARRHAIDRMVKNAKQMGGNAVVMMRFDSSEIGQTMSEIVAYGTVVVVEKLST</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3S8</accession>
    <name>A0A2S9H3S8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0648</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94645">
        <property type="protein sequence ID" value="PRC94645"/>
        <property type="gene ID" value="S2091_0648"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="71"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="124"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="7"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="144" mass="15368" checksum="CEE34862B21DC8BB" modified="2018-07-18" version="1">MATSTGWFYWAILSAIFAALTAIFAKIGIQGVDSDLATLIRTAIIGVVLSAFVACTGKWSNPLDLSMKTWLFLGLSGLATGASWVCYFRALKIGEASKVAPVDKFSLVLVAVFAFAFLGERPSLRDWVGIAMVAGGVLLLAFKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3T0</accession>
    <name>A0A2S9H3T0_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ubiquinone biosynthesis accessory factor UbiK</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">ubiK</name>
        <name evidence="2" type="ORF">S2091_0529</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Required for efficient ubiquinone (coenzyme Q) biosynthesis. UbiK is probably an accessory factor of Ubi enzymes and facilitates ubiquinone biosynthesis by acting as an assembly factor, a targeting factor, or both.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; ubiquinone biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the UbiK family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94526">
        <property type="protein sequence ID" value="PRC94526"/>
        <property type="gene ID" value="S2091_0529"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00232"/>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006744">
        <property type="term" value="P:ubiquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02216">
        <property type="entry name" value="UbiK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007475">
        <property type="entry name" value="UbiK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38040">
        <property type="entry name" value="PTHR38040"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04380">
        <property type="entry name" value="BMFP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0831">Ubiquinone biosynthesis</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02216"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="77" mass="8822" checksum="312486B2D20791D1" modified="2018-07-18" version="1">MNQIFNDIQSKINEALEKSPAKDLEKNVKAMMSQGFAKLDLVTREEFDIQAQILAKTRAKLEALEARVMELENQARE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H480</accession>
    <name>A0A2S9H480_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Response regulator receiver domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0764</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94761">
        <property type="protein sequence ID" value="PRC94761"/>
        <property type="gene ID" value="S2091_0764"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042802">
        <property type="term" value="F:identical protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011717">
        <property type="entry name" value="TPR-4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07721">
        <property type="entry name" value="TPR_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="8"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="538" mass="59928" checksum="CD8501FB8D10CF1F" modified="2018-07-18" version="1">MSELTEIRVLLIEPHSGMRASIHNMLNLCGVTRIEHGISSGTGLSSIKAKYFDLILCEYELGAGQDGQQLLEDIRHHKLAPLSTIFIMVTAERSYEKVVSAAELAPNDYLLKPFTPDGLLDRITRALKKRANFMRIYQLMDNGNYPGAIAECIESEERHERDRVDFMRLRAELHILMGEPELAEPVYKQLTEMRTVAWARLGLAKSMHLQGRYEEAGDILKTLVVENDRYMDAFDLLAKNHEETGQLESAKNVLSAAVEISPHGVRRLRKLGEIALSTGDFSCAELNLKKVVSKVKYSDFKDPEDHVNLVQALVQTGNIDQAKSVIRDLEKTMPDKLKTAACRAISTAFIHAKNNDPRLAEELINAVAASRENIGLSTSMKLGLAKNCLDSNMHEEASEVILEVMRNSTNSNEMQRAIGVFESAGQGELGNKLANQSRAEVMELVAAGVQKAKIGDYRGSVELMSAAVKQLPNNPQVVMNAALAYLKYLENHGWEQKLAEQARRLIDASCRLDPANARNAALRKLYEELQKKYGISRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4B7</accession>
    <name>A0A2S9H4B7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0029</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94834">
        <property type="protein sequence ID" value="PRC94834"/>
        <property type="gene ID" value="S2091_0029"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="86" mass="9779" checksum="EF6263D895625C44" modified="2018-07-18" version="1">MYNEEFTKSTNTGTYIDNPPHLPADKTKKNQLIRHFAQPGKKRMENSDKKAALCKEFYSAYFQYQKFFFDVITSNSAAVSASGTPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4E7</accession>
    <name>A0A2S9H4E7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Peptidase family M48</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_0055</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="6">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the peptidase M48 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94860">
        <property type="protein sequence ID" value="PRC94860"/>
        <property type="gene ID" value="S2091_0055"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001915">
        <property type="entry name" value="Peptidase_M48"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01435">
        <property type="entry name" value="Peptidase_M48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 6" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1 6" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 6" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="93"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M48" evidence="8">
        <location>
            <begin position="154"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC94860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="328" mass="36785" checksum="DB5225323962B06A" modified="2018-07-18" version="1">MISARYFDGKTSRLHHVHLSVENNIARITGDIVREATIQDLRVSERTTHAARRVTFPDGAYLETFDHEAFNAMLSASGYQDSWVVRLQQNWRATIAAALFTIVLLLLTYLYALPSAAKYIANNLPDSVEQTMGKEALSFLDARTFSASKLPLEQQEKINSRFQQLCLAQDSSSPVELVFRSSKIGPNAFALPSRQIVLTDEIVTLLDNDDELMSILSHELGHLHEHHFTRRLIQSSVIAAGATLLFGDVSAVIAGVPTLLLDLKYSRDVERDADDYAVALLKKNNIAVENFAQAFEKMDKLSKGMEPIPYMSTHPITKERIKRVRQAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4F3</accession>
    <name>A0A2S9H4F3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0054</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94859">
        <property type="protein sequence ID" value="PRC94859"/>
        <property type="gene ID" value="S2091_0054"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010295">
        <property type="entry name" value="DUF898"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05987">
        <property type="entry name" value="DUF898"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="75"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="104"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="149"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="200"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="241"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="291"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="361" mass="41042" checksum="867769512D215A2B" modified="2018-07-18" version="1">MTLADDVLAPEVTEHHQDSPQKFSFTATGSEYFRIWIVNLLLSIVTLGIYSAWAKVRRNRYFYSNTHLAEGSFDYHGNAIAILKGRIAAFAIFALYNLSLKTSPTYFLIMLVVMAAILPWLLWKSLQFRLYNSSYRGLRFGFRGSAKQAYKYFLALPILSLFTLYLLVPFTHQRIKKFQHNESRFGSTHFSFNAKVGDFYLTYLIGFVLSAAGMVVITSLFGAGFMALVKQPQHGGINPALMSSIFFFIFAVYAWIFIIYPIFLTMIQNLIWNSTKLGEHQFKSDLKWGKMTFIILTNILGVICTLGLFAPFAHVRYMKYKIESMTLIPNGSIDNFITATEEQISATGDGVADMLDFDLSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4F5</accession>
    <name>A0A2S9H4F5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">GDSL-like Lipase/Acylhydrolase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0042</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94847">
        <property type="protein sequence ID" value="PRC94847"/>
        <property type="gene ID" value="S2091_0042"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013830">
        <property type="entry name" value="SGNH_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13472">
        <property type="entry name" value="Lipase_GDSL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="domain" description="SGNH_hydro" evidence="2">
        <location>
            <begin position="202"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="426" mass="45059" checksum="11084E2C664551FF" modified="2018-07-18" version="1">MNRSTFIHRAVVMMFGLMFGLIGAITLCWSSTDNHWVVTWSAVADQAGPALRGATIRQVVHTSIGGSNVRIRLSNLFGTGPITIESAHLALHATGSAIQAGSDHPLTFQGVSTLKIAKGESALSDPISMPVTALQELAISLYLPANNGPSTIHGVGMETAYIKRGSDMTAAISLASAKTDESHYFLTNVEVTGTDTAGVIVAIGDSIADGVGSTMDAGNRWSDVLASRLQKDPALKSVAVANTGIAGNRILQDAADPFRGQSALNRFDPDALSMPGVRWIILDMGLNDIGAASLLGTAKAKVSSQQIIEGMQTLITRAHEKNIKIIGTTVTPFSGVHFGSGKHPYYSSAGEAKRQEVNTWIRSAHAFDAVADFDQVLRDPDHPEKIRPAYDSGDHLHPNDAGHKALAEAIDLHIFSASGSIKVAIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4Y5</accession>
    <name>A0A2S9H4Y5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0223</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95028">
        <property type="protein sequence ID" value="PRC95028"/>
        <property type="gene ID" value="S2091_0223"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC95028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="109" mass="12340" checksum="BE0D00F68C2C7723" modified="2018-07-18" version="1">MIYEILIRGNNGKQMSSDNLIWIESNLPTRSFEQWLLSRDLLNHSGTAPVVRWSIVQTKRPAHFVLSTQAAALEQRIADLMNPPVRIKKVARVINVLPNFVLNAFSMAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H509</accession>
    <name>A0A2S9H509_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cation/multidrug efflux pump</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0242</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95047">
        <property type="protein sequence ID" value="PRC95047"/>
        <property type="gene ID" value="S2091_0242"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2090.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027463">
        <property type="entry name" value="AcrB_DN_DC_subdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001036">
        <property type="entry name" value="Acrflvin-R"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32063">
        <property type="entry name" value="PTHR32063"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00873">
        <property type="entry name" value="ACR_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00702">
        <property type="entry name" value="ACRIFLAVINRP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82714">
        <property type="entry name" value="SSF82714"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="336"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="360"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="386"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="427"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="459"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="535"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="852"/>
            <end position="870"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="882"/>
            <end position="901"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="907"/>
            <end position="928"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="956"/>
            <end position="975"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="987"/>
            <end position="1010"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC95047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="1039" mass="113317" checksum="D6D6CD9BA18F1D05" modified="2018-07-18" version="1">MWITKVSINHPVFATMVMVGLMVLGLFSYQKLGVEKMPNVEIPGLFISVQYPGTAPEAIETDITKPIEEAVNTVNGIKRILSSSYEGRSQTYIEFNLNVNMDRAVQDVRDKVASVRPGFPKNVKEPFISRFDGDNAQPVTTLGITSKSRSLRDLSTLTEQIIVKRLQGVPGVGKVDVGGTVARQILVELNPAKMTAMNVGVDEVVAAIQATNQDMPAGRISLDGFDKLVRIEGKLKDPRSFGKIIVARRFDNPVLLEQVADIIDGAREEASISRINGEPAINLNIVKIQDANIVDVGNAIKETVAELKKNLPEDVEIQTVFDSASEVKGSLDRVKSTIMEGAALTILIVFLFLHSWRSTIITGLTLPISVIATFIALHAFGFTLNFLTLMALSLCIGLLIDDAIVVRENIVRHFAMGKSHIQAARDGTNEIGLAVTATTLAIVAVFVPVAFMDGIIGRFFFQFGVTVAVAVLVSLFVSFTLDPMLSSIWQDPVESRFKYLPWLERLMQKIEIGIEALHVVYGRILESALRWRKTTLMFAFGLFIGSFFLLPFIGTDMMPDTDNGFIQLKFKTPVGSSLAYNNSKLLQVEAALREFKEIKTINTTVGSDGNRNESTVGLKLVDLKTTQRPSQKQIEQLIRRRLSSIPGADLSVGFDKPIYVAILGPDPDKLKEVVNHVMQKIAAIKGITELENSMTASNPSVTVKVNNELASDLGLSIQQIGTALRPFIEGDTTNHWLAPDGQNYEINVQLPKSGREKIADLADLSVASNRLTADGKVMMIPLRQVVEFIPSNSPQVIKRQNLQRRVGIYANVDGRTTGDVGTDVQKLVSTIQLPPGYSFDVGGQTKDMQDSFMSAVAALGIAVIFIYLVLASQFGSFLQPLAIMVSLPLSLIGVFSALLITGSTLNIFSIIGFIMLMGLVTKNAILLVDFTNQAQRHGATQHDALLEAGQVRLRPIMMTTLAMLFGMLPMAIGVGEGGELQAPMGRAVIGGIITSTLLTLVVVPVAYSYLDSWGKRALRIFKGKGHHDVVEVKSVVVTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H539</accession>
    <name>A0A2S9H539_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 4">Ferric uptake regulation protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">fur</name>
        <name evidence="5" type="ORF">S2091_0300</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the Fur family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95105">
        <property type="protein sequence ID" value="PRC95105"/>
        <property type="gene ID" value="S2091_0300"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07153">
        <property type="entry name" value="Fur_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002481">
        <property type="entry name" value="FUR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043135">
        <property type="entry name" value="Fur_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33202">
        <property type="entry name" value="PTHR33202"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01475">
        <property type="entry name" value="FUR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0678">Repressor</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3 4" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00020910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU364037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC95105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="141" mass="16012" checksum="615A42249C05CC2A" modified="2018-07-18" version="1">MTNPPNLKSSGLKATLPRLKILEIFQNSSVRHLSAEDVYKILLNDNMDVGLATVYRVLTQFEQAEIIHRNHFETGKAVFELNEGSHHDHLVCINCGKVEEFYDAEIEQRQQMIATERGFTITEHSLAIYGNCIKPNCPNKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H548</accession>
    <name>A0A2S9H548_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Magnesium-transporting ATPase, P-type 1</fullName>
            <ecNumber evidence="5">7.2.2.14</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Mg(2+) transport ATPase, P-type 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">S2091_0282</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Mediates magnesium influx to the cytosol.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O + Mg(2+)(out) = ADP + H(+) + Mg(2+)(in) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:10260"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="7.2.2.14"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell inner membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.2.2.14" evidence="5"/>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95087">
        <property type="protein sequence ID" value="PRC95087"/>
        <property type="gene ID" value="S2091_0282"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015444">
        <property type="term" value="F:P-type magnesium transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd02077">
        <property type="entry name" value="P-type_ATPase_Mg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006068">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004014">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006415">
        <property type="entry name" value="P-type_ATPase_IIIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00689">
        <property type="entry name" value="Cation_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00690">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01836">
        <property type="entry name" value="MGATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00831">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="SSF81653"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="SSF81660"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="SSF81665"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01524">
        <property type="entry name" value="ATPase-IIIB_Mg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-1278">Translocase</keyword>
    <keyword evidence="7 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="100"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="125"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="309"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="339"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="789"/>
            <end position="812"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="824"/>
            <end position="842"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="854"/>
            <end position="878"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="890"/>
            <end position="912"/>
        </location>
    </feature>
    <feature type="domain" description="Cation_ATPase_N" evidence="15">
        <location>
            <begin position="49"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00013555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00029806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM00831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="PRC95087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="919" mass="102342" checksum="79A88BBCC05D3E86" modified="2018-07-18" version="1">MNFFKNLFARFLQTRHAKHHFERSKMLDSLSGNTVSRTVPEHLALHLLRSAREDQRELIERFNSHTDGLSNSEAAAIREHSGPNEVEHEKPLPRWHHLWLCYKNPFNLLLTVLAIISYLTEDLKATIVIATMVALSTLIRFIQEGRSNRAAENLKAMVSNTATVVRRDTSKEASDIAMLYFSAQIHTRPAHNIELPIQHLVPGDLILLSAGDMIPADCRVLSAKDLFVSQAAMTGESLPIEKFADITEVNGSNPLELTNILFMGTNVVSGSAMALVLSTGNQTYFGTIATRVTSTDRAPTAFQAGVNSVSWLLIRFALVMVPIVLLVNGFTKGDWMEAFLFALAVAVGLTPEMLPMIVTSTLAKGAVLLSRKKVIVKRLDAIQNFGAMDVLCTDKTGTLTQDKIFLERHTDVFGNDSDEVLKFAYLNSYYQTGLKNLLDRAVLDHVELQTELKLAQDYQKIDEVPFDFQRRRMSVVVSEQEDHHELICKGAVEEILASCTHVLDGKNSVPLDDTMLQRVLNVTRDLNQEGLRVVAVAVKEVPPNKINYSIQDEAELTLIGYIAFLDPPKESTAPALRALAEHGVTVKVLTGDNELVTAKICREVGLAVNGMVLGSTLDDMSDEQLSTVVEENSIFAKLTPLHKERLVRMLRQNGHVVGFMGDGINDAPALRAADIGISVDSAVDIAKEAADIILLEKSLMILEEGVLEGRKTFSNMLKYIRMTASSNFGNVFSVLVASAFLPFLPMLPLQLLVQNLLYDVSQIAIPFDNVDEELIKKPLKWNPGDIGRFMLFFGPLSSIFDISTFVLMWFVFHANSVADQTLFQSGWFVVGLLTQTLIVHMIRTQKVPFFQSRAAWPLMIMTAIIMAIGIFLPMGPFADYIKLEELPLSYFPWLIGILIAYAALVQFMKGIYVKRYGWQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5B9</accession>
    <name>A0A2S9H5B9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0380</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95185">
        <property type="protein sequence ID" value="PRC95185"/>
        <property type="gene ID" value="S2091_0380"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016798">
        <property type="term" value="F:hydrolase activity, acting on glycosyl bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.400.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="Glyco_hydro_13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045857">
        <property type="entry name" value="O16G_dom_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00642">
        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aamy" evidence="1">
        <location>
            <begin position="31"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC95185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="560" mass="62855" checksum="AE53B4CEF9B8CB84" modified="2018-07-18" version="1">MSDSFNSVINSNSVEQANSANDWWREAVIYQVYPRSFFDTDGDGVGDLAGITAKLDYIAGLGVDIVWISPFFTSPMRDFGYDVADYCNVDPLFGSLADFDLLIARAHQFGLKIMIDQVLSHSSDQHPWFIESRQSRDNPKSDWYVWTDPQPDGTPPNNWLSIFGGSAWQWDSRRRQYYFHNFLTSQPDLNFHQPQVQQAHLDNMQFWLERGVDGFRIDACIFHFHDEQLRNNPPAKIQNTVSVAASNPYGLQAHIYDNTRPENLQFFKRVRTLLNKYNAISIGEIGSDEALSTMAAYTADGDKLHMAYSFNLLTSDNTTQHISAQVDEFQAKANASPLPGWASWSIGNHDVNRVMSRWGDATTTTEFAKVLLAMQLVLKGTPCLYQGDELALTEADLPYEVLQDPVGLTFWPEMKGRDGCRTPIPWDGAQKNAGFSSGCAWLPVPPEHAAAAVAQQSLDPASPLNFARHFIHWRKTIKQLTRGDIFFYDSPEPLLALRRDLDGMPSVIVVLNLGSQKINFNLPDCSTYQALEGHGFVGSMVDGEISLPAYGAWFGVQKQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5C8</accession>
    <name>A0A2S9H5C8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0363</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95168">
        <property type="protein sequence ID" value="PRC95168"/>
        <property type="gene ID" value="S2091_0363"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010727">
        <property type="entry name" value="DUF1302"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06980">
        <property type="entry name" value="DUF1302"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC95168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="592" mass="64489" checksum="A99461215AD84474" modified="2018-07-18" version="1">MNHRKISLFVASAIAIMTDQVYATDIEIADGTLTVNATVVAGTALRTENPNPSLLSPANAKAIGLSGISPNGGNGDDGDLNYKRWSQTSTILKGYLDLDYVNQNYGAHMGIKAWNDFALENQNVLWGNLPNGYANGTPLSDKGFSSEAKFNGAELTSMYLYGENEIGEGKVEWKIGEQSWNWGRDFQIGCGLNDLLVRDNNALVRPGALPEETVIPIPALRAVYSVTPSTSIDMIVQTRFQSNAALGCGTFYSQVDFVSNGCNQIIVANAITAPEAISKGFYVTRAGDIKPGNAAQGGIGIRQDIPSLDSTVGLYLAQFDSRQFFYGTYKSTNAIPFLPSNPNNGNPQYALEYPGDIRMVGLTYDIERSEGNILAELTYRPDQPYHYNTIDLLNAFVSNTASTPLRGLANSTQAGQLFNGYEKMKAVQFNLSATQTFSHLMAADVVTLIGEFAVKVAPDLPDQSVMRFGRPMFFGSAPIGGAACQSSLTQMECSNAGYDTRSSWGYKLRLNFDYPQLVAGVDFDPKISFAQDVRGWSDDGVFSQGRKFAVIDLKTIYHKSINIDLVWIPTWGGDFNPMSDRSTLGINVGYKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5I9</accession>
    <name>A0A2S9H5I9_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF4136 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0432</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95237">
        <property type="protein sequence ID" value="PRC95237"/>
        <property type="gene ID" value="S2091_0432"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025411">
        <property type="entry name" value="DUF4136"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13590">
        <property type="entry name" value="DUF4136"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5016239807" description="DUF4136 domain-containing protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4136" evidence="2">
        <location>
            <begin position="35"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC95237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="189" mass="20790" checksum="920FC730BDDFA6D0" modified="2018-07-18" version="1">MKRSLILFTVVLTALLAGCAAPSVVSNVTVFHTLTGTETNKTYMVEATPEQANNLEFSSYVTLLNQELQHVGYVMVNKDPSLKVSLNYGTTQAVASSLQPAPIYGPYGFRHGPYYGSGWQTSVDTVFMHHMEVSISRIADGKNIYTVRSRLMSPNPELSISMDYLMDSAFQNFPGKNGSTETITLPVHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GS80</accession>
    <name>A0A2S9GS80_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">YD repeat (Two copies)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4717</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000051">
        <property type="protein sequence ID" value="PRC90579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90579">
        <property type="protein sequence ID" value="PRC90579"/>
        <property type="gene ID" value="S2091_4717"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031325">
        <property type="entry name" value="RHS_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006530">
        <property type="entry name" value="YD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05593">
        <property type="entry name" value="RHS_repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01643">
        <property type="entry name" value="YD_repeat_2x"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC90579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="246" mass="26518" checksum="AFF959ACB442B31F" modified="2018-07-18" version="1">MYPSGRQLIYTRDALGRVTQLTSINNGTTINIVTNVLYAPTGKVLSYVNGTGNTVKYTTDLDGRTTSYSLNQQNRILNYDAGSRLVTQTDPAQNVTYTYDALNRLNSAINATSSFSYSYDPVGNRTTMGNGGTNTQYSYGSTSNQLTQVSGSQVNTIQSDANGSITNNVNNQFGYDARGRMVSAQTAIGSVQYQINALGQRVLKVTPNGTTVFNYDQSGKLIGESTGTKGADYIYLNDIPVAVAQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSA4</accession>
    <name>A0A2S9GSA4_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Toprim domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">S2091_4697</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000046">
        <property type="protein sequence ID" value="PRC90590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90590">
        <property type="protein sequence ID" value="PRC90590"/>
        <property type="gene ID" value="S2091_4697"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990077">
        <property type="term" value="C:primosome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003896">
        <property type="term" value="F:DNA primase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03364">
        <property type="entry name" value="TOPRIM_DnaG_primases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.980.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013264">
        <property type="entry name" value="DNA_primase_core_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037068">
        <property type="entry name" value="DNA_primase_core_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036977">
        <property type="entry name" value="DNA_primase_Znf_CHC2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034151">
        <property type="entry name" value="TOPRIM_DnaG_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006171">
        <property type="entry name" value="TOPRIM_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002694">
        <property type="entry name" value="Znf_CHC2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08275">
        <property type="entry name" value="Toprim_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01807">
        <property type="entry name" value="zf-CHC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00400">
        <property type="entry name" value="ZnF_CHCC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50880">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0235">DNA replication</keyword>
    <keyword evidence="1" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="2" id="KW-0639">Primosome</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Toprim" evidence="11">
        <location>
            <begin position="262"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="395"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="950"/>
            <end position="976"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PRC90590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="1022" mass="112728" checksum="74FDF6C0226B3F82" modified="2018-07-18" version="1">MARISETTIEQLKKEVSVERLIEAAGIALKKTGKDKTGLCPFHEDATASLVVTPAKNLWHCFGCGVGGDPIAWVMKFRGISFRHAVELLQADPSLAAKGVSDGPIKVATVRTLPAPVTFDADDQVLLNQTVDYYHQTLLASLDAQAYLQSRGLTHPDLIAEFKLGYANRSLGLRLPDKHRKAGLDIRTRLEKIGIYRASGHEHFNGSLVVPILDENSNVTELYGRKITDGLRKGTPQHLYLPAELRVAGRGIFNRQALATHKEIILCEAIIDAMTFWCAGYRNVTTSYGIEGFTEEHLAAFQQHGTERVLIAYDRDDAGERGAEKVATQLMAHSIDCYRIQFPKNMDANEYAIKVQPATQSLGILIRKALWLGNGKAPERTALQPVAAVPVTPLATPEKAEQATESEAAVMPPLTPLPASPLPPAPASDIDCAVSDTEIVLTFAERRYRVRGLSKNLAYDLLKVNLLASVGDAFHVDTLDLYNARARQSFVTQAAFELHLSDDAIKTDLGRVLLKLETLQDAQIKSALKPKQAEVVVMDAADKQAALALLRDPNLIERLQADCTVCGLVGEDINKLVGYLAAVSRKRDKPLGVVIQSSSAAGKTSLMDTVLAFVPPEDKVKYSAMTGQSLFYMGETNLKHKVLAIVEEEGASRASYALKLLQSEGELTMASTGKDPITGNLVTQPYRVEGPVALLLTTTARDLDEELMNRCLILSVDESRDQTRAIHHLQREKRTLNGMIANQEKASLIALHQNAQRLLRPIAIFNPYVQWLTFPDQTTRLRRDHEKYLTLIDTITFLHQHQRDLRSTHRGAINVEYVEVTLDDIALANRIAHDVLGRSLDELPPQTRRLLSTMDSYVQEQCKQRSLQRSDCRFSRRTLREAINWGDTQLKLHLARLVELEYIVTHRTANNGFDYELVYAASGDGHRLHFPGLADIATLKHAYDVSRSGHNATRSAAGRGVVGQRSPLGREPILSQEPATTPNCVEVVAENAKTHYIEAHSKIVSYPQTSPVLPLAASAVSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSA7</accession>
    <name>A0A2S9GSA7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Rhodanese-related sulfurtransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4693</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000045">
        <property type="protein sequence ID" value="PRC90604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90604">
        <property type="protein sequence ID" value="PRC90604"/>
        <property type="gene ID" value="S2091_4693"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="SSF52821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Rhodanese" evidence="1">
        <location>
            <begin position="5"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="97" mass="10547" checksum="A1A597CAECE7F921" modified="2018-07-18" version="1">MIEAGPRPPHLLDLRSQALVNETGIIPHAHIIEYDAISSSLGNISKDYPIVTICACPQDAGAVQVARNLQQLGYRYAHPLRGGFEAWKTAIEKNLAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSF0</accession>
    <name>A0A2S9GSF0_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Arginine--tRNA ligase</fullName>
            <ecNumber evidence="9">6.1.1.19</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Arginyl-tRNA synthetase</fullName>
            <shortName evidence="9">ArgRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">argS</name>
        <name evidence="13" type="ORF">S2091_4661</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg)</text>
            <dbReference type="Rhea" id="RHEA:20301"/>
            <dbReference type="Rhea" id="RHEA-COMP:9658"/>
            <dbReference type="Rhea" id="RHEA-COMP:9673"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32682"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78513"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.19"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="9">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9 10">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.19" evidence="9"/>
    <dbReference type="EMBL" id="PUGF01000042">
        <property type="protein sequence ID" value="PRC90625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90625">
        <property type="protein sequence ID" value="PRC90625"/>
        <property type="gene ID" value="S2091_4661"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004814">
        <property type="term" value="F:arginine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006420">
        <property type="term" value="P:arginyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00671">
        <property type="entry name" value="ArgRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00123">
        <property type="entry name" value="Arg_tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001278">
        <property type="entry name" value="Arg-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005148">
        <property type="entry name" value="Arg-tRNA-synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036695">
        <property type="entry name" value="Arg-tRNA-synth_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035684">
        <property type="entry name" value="ArgRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008909">
        <property type="entry name" value="DALR_anticod-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11956">
        <property type="entry name" value="PTHR11956"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03485">
        <property type="entry name" value="Arg_tRNA_synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05746">
        <property type="entry name" value="DALR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00750">
        <property type="entry name" value="tRNA-synt_1d"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01038">
        <property type="entry name" value="TRNASYNTHARG"/>
    </dbReference>
    <dbReference type="SMART" id="SM01016">
        <property type="entry name" value="Arg_tRNA_synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00836">
        <property type="entry name" value="DALR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="SSF47323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55190">
        <property type="entry name" value="SSF55190"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00456">
        <property type="entry name" value="argS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9 10" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="6 9 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 9 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 9 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 9 10" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Arg_tRNA_synt_N" evidence="12">
        <location>
            <begin position="7"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="domain" description="DALR_1" evidence="11">
        <location>
            <begin position="454"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'HIGH' region" evidence="9">
        <location>
            <begin position="130"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM01016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PRC90625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="576" mass="62820" checksum="34D477E34103FF91" modified="2018-07-18" version="1">MLAQQKQHLITLINTAIAPLLVGSDLTPTPTLERPRDVAHGDIACNIAMQIAKPLKKNPRELAQAIVANLMAQPDDVLASAEIAGPGFINIRVKDSAKQAVIKQILQQAENFGKSTRGANAPVVVEFVSANPTGPLHVGHGRQAALGDSISALMTAQGFAVTREYYYNDAGVQIENLALSVQARARAFQPGQAGWPESAYNGDYIAEIAADFLAKKTITGSDGAATVISATASGDVNDIDSIRHFSVCYLRREQEMDLQAFGVKFDHYFLESSLYTDGKVAAAVSALQNSGKTYEQDGALWLRSTDYGDDKDRVMKKSDGTYTYFVPDVAYHITKWQRGFKKAVNIQGSDHHGTIARVRGGLQAVAMDIPVGYPDYVLHKMVTVMKDGAEVKLSKRAGSYVTLRDLIEWSGNGDIQIGRDAVRFFLISRKADTEFVFDVDVALARSDENPVYYVQYAHARICSVLEKVGEELVSAVLADSQTIDLAPLTAPREASLLAKLAEYPESLERALDELGPHQVAFYLRELAGEMHSYYNAERVLVEDTALKMARVALLLATKQVLQNGLRLIGVTAPVKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSF4</accession>
    <name>A0A2S9GSF4_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">ATP synthase subunit delta</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">ATP synthase F(1) sector subunit delta</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">F-type ATPase subunit delta</fullName>
            <shortName evidence="7">F-ATPase subunit delta</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">atpH</name>
        <name evidence="8" type="ORF">S2091_4651</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.</text>
    </comment>
    <comment type="function">
        <text evidence="7">This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the ATPase delta chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000041">
        <property type="protein sequence ID" value="PRC90643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90643">
        <property type="protein sequence ID" value="PRC90643"/>
        <property type="gene ID" value="S2091_4651"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045261">
        <property type="term" value="C:proton-transporting ATP synthase complex, catalytic core F(1)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.520.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01416">
        <property type="entry name" value="ATP_synth_delta_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026015">
        <property type="entry name" value="ATP_synth_OSCP/delta_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000711">
        <property type="entry name" value="ATPase_OSCP/dsu"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11910">
        <property type="entry name" value="PTHR11910"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00213">
        <property type="entry name" value="OSCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00125">
        <property type="entry name" value="ATPASEDELTA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47928">
        <property type="entry name" value="SSF47928"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01145">
        <property type="entry name" value="ATP_synt_delta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 7" id="KW-0139">CF(1)</keyword>
    <keyword evidence="2 7" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="3 7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC90643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="176" mass="18717" checksum="0F429D1B68A6B8BF" modified="2018-07-18" version="1">MAEIATIARPYAEALFRVAKTNLSAWAELVEEMSQAAQHADVKALVQNPKVPATMVADTFLSVLKSPVNQEAKNFINTLASNHRLLVLPEIAAQFHALKNAHEGAADAVISSAFALSDAQVSTLCATLEARFGRKLNPSVTVDAALIGGVRVVVGDEVLDTSVRAKLQKMQLALTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSJ1</accession>
    <name>A0A2S9GSJ1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">tRNA threonylcarbamoyl adenosine modification protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4585</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000038">
        <property type="protein sequence ID" value="PRC90692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90692">
        <property type="protein sequence ID" value="PRC90692"/>
        <property type="gene ID" value="S2091_4585"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003725">
        <property type="term" value="F:double-stranded RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017945">
        <property type="entry name" value="DHBP_synth_RibB-like_a/b_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006070">
        <property type="entry name" value="YrdC-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01300">
        <property type="entry name" value="Sua5_yciO_yrdC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55821">
        <property type="entry name" value="SSF55821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00057">
        <property type="entry name" value="TIGR00057"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51163">
        <property type="entry name" value="YRDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YrdC-like" evidence="1">
        <location>
            <begin position="14"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="207" mass="23155" checksum="8ACE4C1B86D816DA" modified="2018-07-18" version="1">MSQYFYLHPDNPQARLIKQASQIIHSGGIVAVPTDSCYALVCHLDDKDAVQRLRRIREVDEKHHLTLLCRDLSEIANYAKVDNRQYRLLKAATPGPYTFILEATKEVPRRLSHPSRKTIGLRVPEHKIIHALLSELGQPLLGATLILPNQELPLTEPEEIRDCLENQIDLIIDGGACSLEPTTVVDLTGEEALLLRLGRGDVSIFGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSK2</accession>
    <name>A0A2S9GSK2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Zn-dependent protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">S2091_4584</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the peptidase M50B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000038">
        <property type="protein sequence ID" value="PRC90691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90691">
        <property type="protein sequence ID" value="PRC90691"/>
        <property type="gene ID" value="S2091_4584"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06158">
        <property type="entry name" value="S2P-M50_like_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044537">
        <property type="entry name" value="S2P-M50-like"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="13 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="6 15" id="KW-0645">Protease</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 14" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="54"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="95"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="132"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="175"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="PRC90691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="220" mass="24735" checksum="720EEFE2BDAA5FA9" modified="2018-07-18" version="1">MNELIQTLAVYAIPMIFAITLHESAHAFVARYFGDDTAYLRGRLSLNPLKHIDPIGTLLLPALMLLVSKGTFAFGYAKPVPVNFSALRNPKRDMIWVALAGPASNFFMALIWFLSIYAMVVIHFDVPFLLKMAQAGIAVNVIMFALNLFPMLPLDGGRILVGLLPMKQAYQFSKIEPYGFFIVLGLLWLNLLDKYWLNPVASWTETSLQLLLTPLQFLIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSS6</accession>
    <name>A0A2S9GSS6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative cytoplasmic domain of flagellar FhlB-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4522</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the type III secretion exporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000036">
        <property type="protein sequence ID" value="PRC90774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90774">
        <property type="protein sequence ID" value="PRC90774"/>
        <property type="gene ID" value="S2091_4522"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1690.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006135">
        <property type="entry name" value="T3SS_substrate_exporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029025">
        <property type="entry name" value="T3SS_substrate_exporter_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30531">
        <property type="entry name" value="PTHR30531"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01312">
        <property type="entry name" value="Bac_export_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160544">
        <property type="entry name" value="SSF160544"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0966">Cell projection</keyword>
    <keyword evidence="2" id="KW-0969">Cilium</keyword>
    <keyword evidence="2" id="KW-0282">Flagellum</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="117" mass="12667" checksum="DADA1A0FC2602B4C" modified="2018-07-18" version="1">MNDASKPSDEATSSVQNAVALAYQAGSSAPTVVAKGKGLVAQAIIARAKEHGIYVHQSQELVALLMQVELDKNIPPALYRAVAELLAWLYHIEKQRDETTPVTPYITTAKDNLKIIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSU2</accession>
    <name>A0A2S9GSU2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4540</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000036">
        <property type="protein sequence ID" value="PRC90792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90792">
        <property type="protein sequence ID" value="PRC90792"/>
        <property type="gene ID" value="S2091_4540"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="69" mass="7914" checksum="16AAA2EAEC746776" modified="2018-07-18" version="1">MAGKWQVAARWGLGMTVSSVPILDGRGSTLRSFKIWKINLFLLVLLFEFSFVGKFELHQNLDQNLSNRM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSX8</accession>
    <name>A0A2S9GSX8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4461</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000035">
        <property type="protein sequence ID" value="PRC90798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90798">
        <property type="protein sequence ID" value="PRC90798"/>
        <property type="gene ID" value="S2091_4461"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015749090" evidence="1">
        <location>
            <begin position="20"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="199" mass="22903" checksum="FDD36EAE4D3FEEA5" modified="2018-07-18" version="1">MIKIFHTLILFLLSMPAFSQFKDPCPTLPVQSGISMIYFRGPDFDICQAMDGDHQFFSIYLGSAPDFHQVINHFIGKAKVGNFDGNWYSKDTDDYFSQIAKETLIDISHSPEDLKIEHFVGRLEFEPPPPPKRAPFAHIWINDLNSADLKKAEFILERIEFKGSRELTCTSFLFSTCIYQNSFPELLKLEYLLHPITAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GT43</accession>
    <name>A0A2S9GT43_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4380</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000033">
        <property type="protein sequence ID" value="PRC90887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90887">
        <property type="protein sequence ID" value="PRC90887"/>
        <property type="gene ID" value="S2091_4380"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC90887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="82" mass="9181" checksum="F5AD40365B48EC82" modified="2018-07-18" version="1">MSQLIANQTSSAEVIKLIQQGQSLQCPVCFSVIKTVPENWKPGMVLHGIECPNDQKHFMIHCDDGQAMKEVRARMKARASKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GT66</accession>
    <name>A0A2S9GT66_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4407</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000033">
        <property type="protein sequence ID" value="PRC90914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90914">
        <property type="protein sequence ID" value="PRC90914"/>
        <property type="gene ID" value="S2091_4407"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC90914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="101" mass="11574" checksum="19292CE64E015CBE" modified="2018-07-18" version="1">MTITSQQLQELMEEVEREDPIDFADLPFNDQDLRSLISNHVCDMAAALENFSEEDKHLTLLAVAAKLVLENFVLHLRLLTKYGVPVNPDVQALLRELRDKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GT95</accession>
    <name>A0A2S9GT95_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">S1/P1 Nuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_4414</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000033">
        <property type="protein sequence ID" value="PRC90921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90921">
        <property type="protein sequence ID" value="PRC90921"/>
        <property type="gene ID" value="S2091_4414"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006308">
        <property type="term" value="P:DNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11010">
        <property type="entry name" value="S1-P1_nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.575.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008947">
        <property type="entry name" value="PLipase_C/P1_nuclease_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003154">
        <property type="entry name" value="S1/P1nuclease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33146">
        <property type="entry name" value="PTHR33146"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02265">
        <property type="entry name" value="S1-P1_nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48537">
        <property type="entry name" value="SSF48537"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0540">Nuclease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015487047" evidence="6">
        <location>
            <begin position="28"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC90921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="311" mass="34221" checksum="167AE6C4A17C7043" modified="2018-07-18" version="1">MSRKKVGGLLATLLYLLACVAPQSAYAWGDDGHQAVALIAWTYLSPDVRTKILDLLKKDNESLAMRNGQNTSDSFATQATWADYYRASSGQYGPAYQQTRNWHFVNIEINGGRLEAACPNYANLLPATLAFNGPANDCIVNKIRQFTAELMSPTTLQTERIRALKMVMHLVGDIHQPLHASDDHDAGGNSKQVSFSGMKPGNLHSYWDTAFVRLIADTPKNIADKLIAAITTTKIKQWSKSESNPSTWANESYALAKKVSYGELPNPRHGSAESVTYQLNQAYVNDAREVIEMQLAKAGIRLAAVLNAAFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTB6</accession>
    <name>A0A2S9GTB6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Acyl-CoA ligase (AMP-forming), exosortase A-associated</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_4354</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000032">
        <property type="protein sequence ID" value="PRC90953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90953">
        <property type="protein sequence ID" value="PRC90953"/>
        <property type="gene ID" value="S2091_4354"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017529">
        <property type="entry name" value="AcylCoA_ligase_PEP_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03098">
        <property type="entry name" value="ligase_PEP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-binding" evidence="1">
        <location>
            <begin position="11"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding_C" evidence="2">
        <location>
            <begin position="437"/>
            <end position="511"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC90953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="531" mass="58249" checksum="11F1C40D3AADDBFA" modified="2018-07-18" version="1">MTDLVHQLILEAAARAPQAEALCYQGQRMSYAELAQQTQQVGQALLTLGVQRSDRVAVYLEKRFETVLAMFGASAAGAAFVPVNPLLKAEQLIYILNDCQVKILVTSAQRLAVVLPLLSECPSLKGVIVVGGDSSTAIASGSHFQLVHWEALEQLHDARTPHCCIDRDIVAILYTSGSTGQPKGVVLSHRNLLAGAQSVAHYLENTADDRVLCVLPLSFDYGLSQLTTVFLTGGTAVLLNYLLPRDILDAVKQERITGLAAVPPLWIQLAALDWSGATSLRYLTNSGGVMQRSTLDILRRNLPDAKIYLMYGLTEAFRSTFLPPEQLDRRPDSIGRAIPNAEVLVLRPDGSECDAEEPGELVHRGALVALGYWNDAEKTAERFKPLPLQLQNSSLPLPEIAVWSGDIVRKDAEGYLYFLGRTDELIKVSGYRVSPTEIEQVICTMDGVSEFAAVGVAHPVLGQAIVAIVKQNSNLTAETLRQQCQRRLPAYMVPMHIVVETEALPRNANGKIDRKALQRRFAHIFNTEFQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTF4</accession>
    <name>A0A2S9GTF4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4293</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000031">
        <property type="protein sequence ID" value="PRC90997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90997">
        <property type="protein sequence ID" value="PRC90997"/>
        <property type="gene ID" value="S2091_4293"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC90997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="69" mass="7588" checksum="CAFD065CD0EB2A6A" modified="2018-07-18" version="1">MNAEFMLLAIYNSPVLTLEQVCHIVGVAKDTAYVQRSNGTFPIPMSGKPLRADVRDVALYMDKTRASAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTF9</accession>
    <name>A0A2S9GTF9_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 8 9">Protein RecA</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8 9">Recombinase A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">recA</name>
        <name evidence="14" type="ORF">S2091_4305</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7 8">Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 8 10">Belongs to the RecA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000031">
        <property type="protein sequence ID" value="PRC91009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91009">
        <property type="protein sequence ID" value="PRC91009"/>
        <property type="gene ID" value="S2091_4305"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009432">
        <property type="term" value="P:SOS response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00983">
        <property type="entry name" value="recA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00268">
        <property type="entry name" value="RecA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013765">
        <property type="entry name" value="DNA_recomb/repair_RecA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020584">
        <property type="entry name" value="DNA_recomb/repair_RecA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020588">
        <property type="entry name" value="RecA_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023400">
        <property type="entry name" value="RecA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020587">
        <property type="entry name" value="RecA_monomer-monomer_interface"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45900">
        <property type="entry name" value="PTHR45900"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00154">
        <property type="entry name" value="RecA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00142">
        <property type="entry name" value="RECA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54752">
        <property type="entry name" value="SSF54752"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02012">
        <property type="entry name" value="tigrfam_recA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00321">
        <property type="entry name" value="RECA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50162">
        <property type="entry name" value="RECA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50163">
        <property type="entry name" value="RECA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 10" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6 8 10" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="8 9" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5 8 10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 8 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 9" id="KW-0742">SOS response</keyword>
    <feature type="domain" description="RECA_2" evidence="12">
        <location>
            <begin position="43"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="domain" description="RECA_3" evidence="13">
        <location>
            <begin position="207"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="362"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="73"/>
            <end position="80"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00015553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025580"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000526"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="PRC91009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="383" mass="40431" checksum="AA5CD4699B066B9D" modified="2018-07-18" version="1">MDDKKPLPNAEKAKALAAALAQIEKQFGKGSVMRMADGEVVEEVAVVSTGSLGLDIALGVGGLPRGRVIEIYGPESSGKTTLALQVIAEMQKLGGTCAFIDAEHALDVGYAQKLDVVLSDLLISQPDTGEQALEITDALVRSGSVDLIVIDSVAALTPKAEIEGDMGASLPGLQARLMSQALRKLTGSINRTNTLVIFINQIRMKIGVMFGNPETTTGGNALKFYASVRLDIRRTGGIKSGEEVIGNETKVKVVKNKVAPPFKEAHFDIMYGEGTSREGEILDLGSDAKIVEKAGAWYSYNGERIGQGKDNARNYLKERPALAREIENKVREHLGVRPLPVIAAPKVSKAAAAAAASALADNVDESSVNAPSAAKAAKAQSKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTJ7</accession>
    <name>A0A2S9GTJ7_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Poly(A) polymerase I</fullName>
            <shortName evidence="7">PAP I</shortName>
            <ecNumber evidence="7">2.7.7.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">pcnB</name>
        <name evidence="13" type="ORF">S2091_4312</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>ATP + RNA(n) = diphosphate + RNA(n)-3'-adenine ribonucleotide</text>
            <dbReference type="Rhea" id="RHEA:11332"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17347"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="ChEBI" id="CHEBI:173115"/>
            <dbReference type="EC" id="2.7.7.19"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="7 8">Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.19" evidence="7"/>
    <dbReference type="EMBL" id="PUGF01000031">
        <property type="protein sequence ID" value="PRC91016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91016">
        <property type="protein sequence ID" value="PRC91016"/>
        <property type="gene ID" value="S2091_4312"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004652">
        <property type="term" value="F:polynucleotide adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006378">
        <property type="term" value="P:mRNA polyadenylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05398">
        <property type="entry name" value="NT_ClassII-CCAase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00957">
        <property type="entry name" value="PolyA_pol"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002646">
        <property type="entry name" value="PolA_pol_head_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010206">
        <property type="entry name" value="PolA_pol_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025866">
        <property type="entry name" value="PolyA_pol_arg_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032828">
        <property type="entry name" value="PolyA_RNA-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01743">
        <property type="entry name" value="PolyA_pol"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12626">
        <property type="entry name" value="PolyA_pol_arg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12627">
        <property type="entry name" value="PolyA_pol_RNAbd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01942">
        <property type="entry name" value="pcnB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1 7" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7 8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6 7" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 7 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PolyA_pol" evidence="10">
        <location>
            <begin position="58"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="domain" description="PolyA_pol_RNAbd" evidence="12">
        <location>
            <begin position="211"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="domain" description="PolyA_pol_arg_C" evidence="11">
        <location>
            <begin position="324"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="424"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="446"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="462"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="76"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="78"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF12626"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF12627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PRC91016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="476" mass="53053" checksum="2C0BE0D4D9E7B411" modified="2018-07-18" version="1">MIKQLIKKIFGSPEPKPVKPAVAKLKTLTVKQHGIDPGLVSSNAVRVTHTLQQAGFKAFIVGGAVRDLLLGVKPKDFDIATDATPEQVKRLFRRAFIIGKRFQIVHVMFGSDLLEVTTFRGAATDGAPKDEFGRVLRDNTFGEQPEDATRRDFTINAMYYDPATQTVLDYHGGMADIRKKTLRIIGQPEARYREDPVRMLRVVRFAAKLQFDIAPTTRAPIPVMAALIDNVPTARVFDEMLKLLTSGHALACLQQLRQEGLHHGLLPLLDVVLEQPLGAKFVTLALNNTDERVKQGKTVSPGFLFASLLWHQVLAKWQAYEAAGEFPIPALHLAADDVLQTQTDSLALQRRIGSDMRDIWAMQPRFDRRVGKTPYKLIEHPRFRAGLDFLVLRAASGEIDQEIATWWTEFLASDNVGRETLLAAKPRSTKKPATSKAQDKVVNKAPAPSDAEEEAETKAAAPRKRRRRPKKPAAME</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTM6</accession>
    <name>A0A2S9GTM6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4255</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000030">
        <property type="protein sequence ID" value="PRC91067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91067">
        <property type="protein sequence ID" value="PRC91067"/>
        <property type="gene ID" value="S2091_4255"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022742">
        <property type="entry name" value="Hydrolase_4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12146">
        <property type="entry name" value="Hydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hydrolase_4" evidence="1">
        <location>
            <begin position="59"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="335" mass="37232" checksum="F98A254A9521EF4E" modified="2018-07-18" version="1">MDIPSLDHREQHFFIPGPHAPLNLFLRYLPATQVIANSSHSSHIVLYVHGASFPSALSIAHRFDGHSWRDELNAAGFDVWGLDFQGFGFSDRYPEMDAPAKLNPALCNTADATEQLHCCVQFILSHHAASRLSIIAHSWGSIPTCRLASIYPTLIDRLVLFGPIARRGPRRYEVAPTATAWGLVTIENQWKRFVEDVPPGVVPVLSQVHFDDWAEHYLDSDPGSRLRDPASVMVPSGPVNDILRAWHGQLGYEPAMVRAPVALIRGEWDGLIPDQDARWLFDAFTASPNKRDIKISGGTHLMHLEAMRFALYRESISFLHGGDLPPDLSPAKGTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GU71</accession>
    <name>A0A2S9GU71_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="10">TonB-dependent Receptor Plug Domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">S2091_4101</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000027">
        <property type="protein sequence ID" value="PRC91206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91206">
        <property type="protein sequence ID" value="PRC91206"/>
        <property type="gene ID" value="S2091_4101"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039426">
        <property type="entry name" value="BtuB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30069">
        <property type="entry name" value="PTHR30069"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="3 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 10" id="KW-0675">Receptor</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="2 6" id="KW-0798">TonB box</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015698138" evidence="7">
        <location>
            <begin position="34"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="domain" description="Plug" evidence="9">
        <location>
            <begin position="75"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="8">
        <location>
            <begin position="262"/>
            <end position="727"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC91206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="730" mass="79353" checksum="61B77AA360B9B6C9" modified="2018-07-18" version="1">MQRTSSTLTRRKLSLAIAGILAASSGYSTLLYAADPAATPPLPAETPTNSANTVVITAPERLKSARTELLPNIGTTVYSVDKHMIDSLGQGDSTPFDDVLLRMPGVVQDSKASGSLHIRDDHGNVQYRINGVELPEGISGFGQAVDTRFIDNIDFVTGALPAQYGLRTAGIIDIQTKEGSVEPGGRIGMLIGSNHYVEPSAEVFGSRGAFNYYLSGSYLQNSIGIENPTASKNPIHDDTHQTKSFGNLSYYLNDDSRISLLFGTYDGKFQIPNNPNQTAQYSLTGYSDLTTGFNSVPSSSLNERQNEENRFMVLSYQKTLGNLNFQISGYHQYSETLYTPDVAGDLIYNGIAAQAMRNSSSNGLQFDTSYKLNAQHTVRGGFAYNRQDTESNNSSQVFPIANGVTSADPVTIIDNSSKTGTTGSFYMQDQWTITKALTFNYGARYDQVSAFIQEHQWSPRLNLAFKATEDTALHAGYSRYFTPPSQELLSQNSIDKYAGTTGAANVPTSDPVKAERTNYFDMGISHKVNAQLSVTADVYYKQITNLLDEGQFGQALILSPFNYAKGYAKGLELSAIYNEKNWGGFLNLSAQKAQGTDIISGQATFGPDELAYIANHYVYLDHDQTFSISGGANTKLGDYKLSGDFIYGSGLRNTPTGGAPNSASLPDYITFNSNITRTWKDTAIGSIEGRIALLNIFDRSYELRDGTGIGVGAPQYGARRTLFVGMSTSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUF2</accession>
    <name>A0A2S9GUF2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative NADP-dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3957</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000025">
        <property type="protein sequence ID" value="PRC91286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91286">
        <property type="protein sequence ID" value="PRC91286"/>
        <property type="gene ID" value="S2091_3957"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016628">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041694">
        <property type="entry name" value="ADH_N_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045010">
        <property type="entry name" value="MDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43205">
        <property type="entry name" value="PTHR43205"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16884">
        <property type="entry name" value="ADH_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PKS_ER" evidence="1">
        <location>
            <begin position="33"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="354" mass="37416" checksum="DE3FD2A35B707F08" modified="2018-07-18" version="1">MKIADLTNTAVNTVTTLKTFQRIVLAARPKGRVSPENFRMETLPQLISSDLAAGEVLVRNHYLSLDPYMRGRMSTAKSYSAPQELDHTMLGATAGVVVASRHAEFSVGDSVVGHLGWAEMGVTQGNLLRQVDAARLPLSVYLGVVGMPGVTAWYGVNRILQAQAGQTLVVSAASGAVGSVVGQLAKLIGCRVVGIAGGEKKCSYVVDQLGFDACVDYKANQTEAELLDCLRAAAPDGIDLLFENVGSSVFDASLACLNPYAKIALCGMIAGYNSASQPLKHANKLLTMRAMLQGFIVTEHMDVWPQALTELAALVASGQLKYHETIAQGLAAAPDAFIGLLSGQNLGKQLVKLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUG8</accession>
    <name>A0A2S9GUG8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3905</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000024">
        <property type="protein sequence ID" value="PRC91360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91360">
        <property type="protein sequence ID" value="PRC91360"/>
        <property type="gene ID" value="S2091_3905"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="467" mass="52064" checksum="88C03178862DAC43" modified="2018-07-18" version="1">MLATLAFIAIVTQDQAQLRAAPKDQAQQQAVLWQGDSLEIRGEKLDYLQVYDHRRERAGYIKASQVRLVSLQPDDAPESMAVVRFLRDTPGAEALGISYTAAFLKAAPATAISPEAFDALGTMAERLARRASTRQSKQNDEIIAAHLDVVAQYGIKIQGYERDGRMQLCYDGEAFRRVLAMNSSEEQKARAALALTRQDCSDPAMRPMERNSLDAWRAEVLDRVVPTGLPEYLKNRLRMRRAAVWSSIAYQRIRKGEAAQDAANRALMELAGVNKEEFTNEDNAAYAEAGVRVGASRWAAETVTTAKSGLTIQTSAGQPGETCVVLVDDKHDQRNPLIKRCTYGVVWTASARANVNGSVLTLAVQPMESWRELWLFHQINGSWIIDVLPPAISDPDLGYAEFAGWVPGTTKMLVAREARVDGRFKRSFEVVNTETLQVENFADQPASLSLFYRWQDPVWKRQTVSLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUU5</accession>
    <name>A0A2S9GUU5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CMP-N-acetylneuraminic acid synthetase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3762</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000022">
        <property type="protein sequence ID" value="PRC91484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91484">
        <property type="protein sequence ID" value="PRC91484"/>
        <property type="gene ID" value="S2091_3762"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003329">
        <property type="entry name" value="Cytidylyl_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02348">
        <property type="entry name" value="CTP_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="224" mass="24766" checksum="CA8D3BAECB3B7D68" modified="2018-07-18" version="1">MKTLALILARGGSKGIPRKNIRLLAGKPLIAWSIQAALNCPQIDSVVVSTDDEEIAQISRTWGAQVPFMRPAELALDSSPSMDAILHALDQLPWFDTILVLQPTSPLRTTADIIACLNFAFTQQANAVVSVCEPANSPYWMYKLGADCRLSKLMDTNDISRRQDLPDVYALNGALYFAQTSWLRRTQSFLTHETVGFVMPADKSIDIDTPLDWKIAELLLSESS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUY2</accession>
    <name>A0A2S9GUY2_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">[Ribosomal protein S18]-alanine N-acetyltransferase</fullName>
            <ecNumber evidence="5">2.3.1.266</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rimI</name>
        <name evidence="7" type="ORF">S2091_3786</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Acetylates the N-terminal alanine of ribosomal protein S18.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>acetyl-CoA + N-terminal L-alanyl-[ribosomal protein bS18] = CoA + H(+) + N-terminal N(alpha)-acetyl-L-alanyl-[ribosomal protein bS18]</text>
            <dbReference type="Rhea" id="RHEA:43756"/>
            <dbReference type="Rhea" id="RHEA-COMP:10676"/>
            <dbReference type="Rhea" id="RHEA-COMP:10677"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:64718"/>
            <dbReference type="ChEBI" id="CHEBI:83683"/>
            <dbReference type="EC" id="2.3.1.266"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the acetyltransferase family. RimI subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.266" evidence="5"/>
    <dbReference type="EMBL" id="PUGF01000022">
        <property type="protein sequence ID" value="PRC91508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91508">
        <property type="protein sequence ID" value="PRC91508"/>
        <property type="gene ID" value="S2091_3786"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008999">
        <property type="term" value="F:ribosomal protein S5-alanine N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017189">
        <property type="term" value="P:N-terminal peptidyl-alanine acetylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02210">
        <property type="entry name" value="RimI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006464">
        <property type="entry name" value="AcTrfase_RimI/Ard1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043690">
        <property type="entry name" value="RimI"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01575">
        <property type="entry name" value="rimI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="6">
        <location>
            <begin position="8"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Acetyl-CoA binding" evidence="5">
        <location>
            <begin position="76"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="110"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="5">
        <location>
            <position position="122"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="115"/>
        </location>
        <ligand>
            <name>acetyl-CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC91508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="156" mass="18030" checksum="F814D8CFA3066D17" modified="2018-07-18" version="1">MTIDWSTLKLEPMQLLDLDEVMAIEQAVYSHPWSIGNFVDSLDLAYDAWVVRSVEGELLGYFVQMPVVDEMHLLTIAVQGLMQGQGLGYFLLKHMAERAKLMQMDAVLLEVRVSNLRALAVYEVFGFLSVGRRKDYYQTEHNQREDALILRYTIQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GV20</accession>
    <name>A0A2S9GV20_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3676</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000021">
        <property type="protein sequence ID" value="PRC91560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91560">
        <property type="protein sequence ID" value="PRC91560"/>
        <property type="gene ID" value="S2091_3676"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015562">
        <property type="term" value="F:efflux transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003423">
        <property type="entry name" value="OMP_efflux"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010131">
        <property type="entry name" value="RND_efflux_OM_lipoprot_NodT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02321">
        <property type="entry name" value="OEP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01845">
        <property type="entry name" value="outer_NodT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0564">Palmitate</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1134">Transmembrane beta strand</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU362097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="494" mass="53910" checksum="AE82127584D33A2A" modified="2018-07-18" version="1">MKSHFLKVVGYGKPSLLIAVLTATLMIGGCAMIKTDSPALPQIDEHQIRLAEDIRLATEAWPQAQWWHRYGDAQLNALIERALKEAPIMAVAQQRLEASKAQTAYSVSTTGLLVGFSASLNRQDLSENGFLGPFAHTIPAQGLTGPWYTEGTMGFSAEYTFDLWGKDRAKVDAALGVQRAHQAETAEVALTLSSKVALTYYDMQSIYAALNLLEQARDLENNMVAAHLARAETGIEARTPTEMVRVHQLGLEQQISAAHSKITILKESLRALTGAGPDNFPEIKPVPLPSDSGALPPTLGYELLARRPDLQAARWYVQASLSQVDMAKAAFYPSFDIKAFFGLDSLHLADLLHRSSTQFNLIPGLSLPIFDGGRLNAALANSRHQSNTLIAQYNQAVVNAVQEVASNGIVLVDLDQQVQLQNARLIAISYKMESAKAHRERGLVDDIVVFESTLPVLEEQARLIELHNRQLTASINLSRALGGGFIQVDTNTSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GV31</accession>
    <name>A0A2S9GV31_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Acetoacetate decarboxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_3701</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000021">
        <property type="protein sequence ID" value="PRC91585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91585">
        <property type="protein sequence ID" value="PRC91585"/>
        <property type="gene ID" value="S2091_3701"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016831">
        <property type="term" value="F:carboxy-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.400.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010451">
        <property type="entry name" value="Acetoacetate_decarboxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023375">
        <property type="entry name" value="ADC_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06314">
        <property type="entry name" value="ADC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160104">
        <property type="entry name" value="SSF160104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0704">Schiff base</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC91585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="246" mass="27133" checksum="E5DDBE9EF9087474" modified="2018-07-18" version="1">MTEDEVRQNGFAMPMHNPAYPPGPYRFVDREFLIITYRTDPVALQKIIPAPLKMIDPIVKFEFINMPDSTGFGHYCESGQVIPVTLNGVPGGYVHSMYLNDHPPIAAGRELWGFPKKLGEPELRIHKDTLLGTLEYSDTRVATGTMGFKHKTLDPKSALAALLAPSYLLKIIPHVDGTQRICELVQYNLTDIIIKGAWSGPGALELASHALAPVASLPVLEVLSATHILADLTLPYGTVVYDYLNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVB7</accession>
    <name>A0A2S9GVB7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative ABC-type transport system involved in lysophospholipase L1 biosynthesis ATPase component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_3610</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000020">
        <property type="protein sequence ID" value="PRC91672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91672">
        <property type="protein sequence ID" value="PRC91672"/>
        <property type="gene ID" value="S2091_3610"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03255">
        <property type="entry name" value="ABC_MJ0796_LolCDE_FtsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017911">
        <property type="entry name" value="MacB_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-1278">Translocase</keyword>
    <feature type="domain" description="ABC transporter" evidence="7">
        <location>
            <begin position="1"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="5"/>
            <end position="12"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC91672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="189" mass="20150" checksum="97C7E82A8D1EF71B" modified="2018-07-18" version="1">MAIVGASGSGKSTLLGLLAGLDVPSTGSVKIDGVDIFKLDEDGRAALRKQKLGFVFQSFQLLGHLTALENVMLPLELRGDQFSGSQAREKAEQMLGRVGLSSRLTHYPKFLSGGEQQRVALARAFVTEPPLLFADEPTGSLDAVTGAAVMELMFSLNRERGSTLVLVTHDPKVAELCDRVLTIAAGQLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVE6</accession>
    <name>A0A2S9GVE6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Response regulator of the LytR/AlgR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_3574</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000020">
        <property type="protein sequence ID" value="PRC91636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91636">
        <property type="protein sequence ID" value="PRC91636"/>
        <property type="gene ID" value="S2091_3574"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007492">
        <property type="entry name" value="LytTR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04397">
        <property type="entry name" value="LytTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00850">
        <property type="entry name" value="LytTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50930">
        <property type="entry name" value="HTH_LYTTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="3"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="domain" description="HTH LytTR-type" evidence="3">
        <location>
            <begin position="146"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC91636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="248" mass="28504" checksum="6D330948CDA7020A" modified="2018-07-18" version="1">MPTAIIADDERLMRDQLVLRLQQVWPELEIVAQAKNGEEAIEMVKLHQPDFAFLDIRMPGKTGLEAAQAIAGLTHIVFITAYDQYAVEAFEHGAIDYVLKPADVDRLSLTVDRLKKRIAQTPNDMSSLIAQLSRQITQKPNYLQWIQASIGSELRLFPVEEILFFQSDEKYTRVQTKTVEALIRKPVRELVEELDPNLFWQIHRSTLVNAKAIDGVIRDMRGRHLVQIKGLTEKLEVSRSYVHLFKQM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVG0</accession>
    <name>A0A2S9GVG0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3650</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000020">
        <property type="protein sequence ID" value="PRC91712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91712">
        <property type="protein sequence ID" value="PRC91712"/>
        <property type="gene ID" value="S2091_3650"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015556391" evidence="1">
        <location>
            <begin position="25"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="87" mass="8534" checksum="BCF9EB23C68402D5" modified="2018-07-18" version="1">MHKNSRKNCHIIALLKLSLLIASASCLLNGCVVIAVADAVVGTTVSVGAAVVGTTVNVGSAVVGSTVDVARAGVRAATSAPDPVVPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVL3</accession>
    <name>A0A2S9GVL3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Gamma-aminobutyrate permease and related permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_3520</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000019">
        <property type="protein sequence ID" value="PRC91765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91765">
        <property type="protein sequence ID" value="PRC91765"/>
        <property type="gene ID" value="S2091_3520"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004841">
        <property type="entry name" value="AA-permease/SLC12A_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004840">
        <property type="entry name" value="Amoino_acid_permease_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00324">
        <property type="entry name" value="AA_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00218">
        <property type="entry name" value="AMINO_ACID_PERMEASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="38"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="123"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="153"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="195"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="237"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="277"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="323"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="354"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="396"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="426"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="domain" description="AA_permease" evidence="7">
        <location>
            <begin position="14"/>
            <end position="452"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC91765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="456" mass="49409" checksum="AE4635B4796EE40B" modified="2018-07-18" version="1">MQKQTMVRGLTARHIRFIALGSAIGTGLFYGSASAIQLAGPSVILAYLIGGVAIYLMMRSLGEMAVHNPISGSFGHYAGQYLGPLAGFLTGWTYALSMMFVCLADVTAVGIYMSFWFPDVARWVWVLSIILFVGALNLCNVKVFGEMEFWLTLIKVGAIVAMIAGGAAIIIFGLGNTQPAGVSHLWQDGGFMPNGIGGMVASFTIVMFAFGGVEIIGISAGEAQDPQKSIPKAINAVPVRILLFYVLTLFVLMSIYPWRQIGSEGSPFVQIFDSLNITFAAAMLNFVVISAAISSINSDIFAAGRMLYGMALKGQAPAGFARLSASGVPTLTVLVMGATLLFGVVLNYLMPEDVFLLCASIVTFACVWVWLVILLSQFSMRMKMSKEEVANLKFPVLFWPYGPIIATAFMVFIFGVLGYFPKTQPALIVGVVWLIVLSIVYKFWMKPFTPKIEQQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVZ6</accession>
    <name>A0A2S9GVZ6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3449</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000018">
        <property type="protein sequence ID" value="PRC91893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91893">
        <property type="protein sequence ID" value="PRC91893"/>
        <property type="gene ID" value="S2091_3449"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045448">
        <property type="entry name" value="DUF6500"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20110">
        <property type="entry name" value="DUF6500"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="73" mass="8358" checksum="5A57593751B62D13" modified="2018-07-18" version="1">MMNTALKQKIIEVCDKKVAQKGSDVGLSFYAFFANKNDDPARLMEAATWWISTHQLDHFEKAIKIKKLAEETL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GW25</accession>
    <name>A0A2S9GW25_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="11 12">ATP synthase subunit a</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">ATP synthase F0 sector subunit a</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">F-ATPase subunit 6</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">atpB</name>
        <name evidence="14" type="ORF">S2091_3269</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11 12">Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11 12">Cell membrane</location>
            <topology evidence="11 12">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11 12">Belongs to the ATPase A chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000017">
        <property type="protein sequence ID" value="PRC91927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91927">
        <property type="protein sequence ID" value="PRC91927"/>
        <property type="gene ID" value="S2091_3269"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045263">
        <property type="term" value="C:proton-transporting ATP synthase complex, coupling factor F(o)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01393">
        <property type="entry name" value="ATP_synth_a_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017692">
        <property type="entry name" value="Alt_ATP_synth_F0_Asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045082">
        <property type="entry name" value="ATP_syn_F0_a_bact/chloroplast"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000568">
        <property type="entry name" value="ATP_synth_F0_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023011">
        <property type="entry name" value="ATP_synth_F0_asu_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035908">
        <property type="entry name" value="F0_ATP_A_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42823">
        <property type="entry name" value="PTHR42823"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00119">
        <property type="entry name" value="ATP-synt_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00123">
        <property type="entry name" value="ATPASEA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81336">
        <property type="entry name" value="SSF81336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03306">
        <property type="entry name" value="altF1_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01131">
        <property type="entry name" value="ATP_synt_6_or_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00449">
        <property type="entry name" value="ATPASE_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 11" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="11" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 11 12" id="KW-0138">CF(0)</keyword>
    <keyword evidence="6 11 12" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="8 11 12" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11 12" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="78"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="108"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="165"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="193"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="227"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="PRC91927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="246" mass="26744" checksum="298C5107BFF3FCAA" modified="2018-07-18" version="1">MNLSSDQLILWQYGFIHLNETIITTWLLMLAMTVGAMLVTRKLATDEKISRWQGALEIIVIGIKQQIEEVGLANPEKYLGFLGTLFLFVATASICTVIPGYVPPTGSLSTTAALALCVFVAVPLFGIEQQGLSGYLKSYLEPTLLMLPFNIISELSRTLALAVRLFGNMMSGTMIIAILLTITPFLFPLVMTLLGLLTGMVQAYIFSILATVYIAAAMQVRAPEPVANLKTNPQPQTPNPKDAPHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GW44</accession>
    <name>A0A2S9GW44_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PRC-barrel domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3285</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000017">
        <property type="protein sequence ID" value="PRC91943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91943">
        <property type="protein sequence ID" value="PRC91943"/>
        <property type="gene ID" value="S2091_3285"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030077">
        <property type="term" value="C:plasma membrane light-harvesting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045156">
        <property type="term" value="F:electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019684">
        <property type="term" value="P:photosynthesis, light reaction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.50.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014747">
        <property type="entry name" value="Bac_photo_RC_H_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027275">
        <property type="entry name" value="PRC-brl_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011033">
        <property type="entry name" value="PRC_barrel-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05239">
        <property type="entry name" value="PRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50346">
        <property type="entry name" value="SSF50346"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PRC" evidence="1">
        <location>
            <begin position="6"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="264" mass="30996" checksum="E785F825C8866D2C" modified="2018-07-18" version="1">MLRNSNEFINCAISATDGAIGHIENFYFDDKTWVVRYLIVDTGNWLFSRKVLISPRAVEQVNWENKTISVNITKEQVKSSPNIDTEKPVSRQHEMTYNGYYGYPYYWEEIGLWGIDDYPPMMMPIYTESLTAPLGVEQEIERSQEQIKSKNYDPHLRSYKEIETYRILTSDGEIGHVKGLLIDEENWIVRYIIVDTTAWWPSQGVLIEIQRIKEVNWADNTIHINLTQQSIIDAPPYDSKELFNQEKEMGLKEHYQRLGYRIGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWB7</accession>
    <name>A0A2S9GWB7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Amino acid permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_3330</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000017">
        <property type="protein sequence ID" value="PRC91988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91988">
        <property type="protein sequence ID" value="PRC91988"/>
        <property type="gene ID" value="S2091_3330"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="32"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="60"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="95"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="122"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="164"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="195"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="236"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="283"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="335"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="393"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="443"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="477"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="521"/>
            <end position="541"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC91988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="546" mass="59240" checksum="920DF6FF15F973A5" modified="2018-07-18" version="1">MDSEVVGTSFSSPGVTHAASGNLHRTLDWRGAFWAASGVPAGVLLTIGGIATTIGQPAWVVWIMSIMMGFVQSFTYAEIAGLFPHKSGGASVYGASAWVGYSKFIAPISVWCNWLAWSPVLALGTGLAAGYIMLSLFPANAAIQTWHLNLADLGWIHQGLTIRINAVFIIAALLLLLTFFLQHHGAAKAARKQKILGIACLFPLVIVGLVPIITGDMPSDHFFPLLPMVRDAAGHIGFGTWNIAGLTLMMGAMFAANWSTFGFETAVCYTREFKNPGSDTFKAILSSGVLCIVMFTIVPLAFQGSLGLDALLDPSIYDGTGVALAMAKMVKGGAIVTNLIIVMLLLSLLLIVMTSMMGSSRTLYQASVDGWLPRYLSKVNEHGSPTSAMWTDLVFNIFLLMLSDYFTVLTISNVCYLLFNFLNLQAGWIHRMDRSDWPRPFRCPTWLLALGGVFGFVNMVFVGAGADVWGEGTLRNGLFAAALILPVFIFRHYVQDKGVFPQHMRDDGAPQGVTTRLRAGILPYLALLACAAVIWISHYFAQFHYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWJ1</accession>
    <name>A0A2S9GWJ1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Patatin-like phospholipase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_3203</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000016">
        <property type="protein sequence ID" value="PRC92068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92068">
        <property type="protein sequence ID" value="PRC92068"/>
        <property type="gene ID" value="S2091_3203"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002641">
        <property type="entry name" value="PNPLA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01734">
        <property type="entry name" value="Patatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="SSF52151"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51635">
        <property type="entry name" value="PNPLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="1 2" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PNPLA" evidence="3">
        <location>
            <begin position="9"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXSXG" evidence="2">
        <location>
            <begin position="49"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="2">
        <location>
            <position position="51"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC92068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="393" mass="42900" checksum="D9C10569252CB067" modified="2018-07-18" version="1">MTANAKTGLILSGGGARAAYQVGVLRAIASLLKEAGWPAHQNPFPIICGTSAGAINATALACSAENFGLGLRRLERVWAGMEAHQIYRADSLAMMRSGARWISILSLGWMLRRWMKTPPSSLLNNDPLAELLTKMLDFTGLDASLASGSLQALAITASSYTTGMHLTFYQTLAEIEPWVRSQRLSQRDFISVQHLLASSAIPFIFPSIPLNWNGDMEYCGDGSMRQLAPISPAIHLGAEKILIIGAGRMSETRRDMPEVISYPSIAQIAGHAMSSIFLDSLAVDIERVTRINRTLSMLPDEYKQQTELRPIKILVISPSQRVDEIATRHIHSLPKPIRVMLGGIGATEARGSALASYLLFESSFTIELMGLGYADTIRMKDEVLAFFGDGRVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWK4</accession>
    <name>A0A2S9GWK4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3229</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000016">
        <property type="protein sequence ID" value="PRC92094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92094">
        <property type="protein sequence ID" value="PRC92094"/>
        <property type="gene ID" value="S2091_3229"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009387">
        <property type="entry name" value="HigB-2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06296">
        <property type="entry name" value="RelE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039032">
        <property type="entry name" value="HigB-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="107" mass="12201" checksum="CA02D6D8923CC2E4" modified="2018-07-18" version="1">MHTIIETPTFQRLWPHYWTEEERGEFAVWLAHNPQAGDVVQGSGGVRKVRWSREGSGKSGGVRVIYFNRLAHGEIVLLFLYAKNELDSVAGEKLKGMKNAIEKAYER</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GX46</accession>
    <name>A0A2S9GX46_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2952</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92293">
        <property type="protein sequence ID" value="PRC92293"/>
        <property type="gene ID" value="S2091_2952"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="38"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="292" mass="32892" checksum="CF070EC09A2E6CE0" modified="2018-07-18" version="1">MIRRSDQVRIESVQCISPDGLHRMAYKEWGEVDNPNVLLCVHGVTRVSDDFDALARELSSQFRVICPDVVGRGRSGWLRNPQHYQVQQYVCDMVTLLARINPPNLSFLGTSMGGLIGIGLASLPENPIQKLILNDIGPVLNISALTRIAQYIGQPMRFATFDEAAQFIRTISQTFGEHTEEEWHKFCMDVLRQDKDGMWIRHYDLKLAVSMQAVSPELAEAMQMMMWAAYDAIACPTLLLRGAESDLLLPETALQMTKRGPRAQLVEFEKVGHAPTLVHADQITVIKDFLLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GX55</accession>
    <name>A0A2S9GX55_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphate transport regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3162</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0111 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92246">
        <property type="protein sequence ID" value="PRC92246"/>
        <property type="gene ID" value="S2091_3162"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038078">
        <property type="entry name" value="PhoU-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018445">
        <property type="entry name" value="Put_Phosphate_transp_reg"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01865">
        <property type="entry name" value="PhoU_div"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="208" mass="23636" checksum="730BFE0EEDEB8738" modified="2018-07-18" version="1">MFGRLMPTEGKFFELFNQHANLCVKGAKEMVELMSNFDDLEIRVHAIEGIEKQADVVTHTCIDLLHKTFITPLDRDDIHQLITRMDDILDLLEDAAQTISLYDIHEVTPEAKRLAELCLACAEKVSSAVALLPNMDNSKEIMHICEEIDRLESDADHVMRAAMSKLFRDEPDVRNLIKLKAIYEILETVTDRCEDVANIIEGIVLENA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXA7</accession>
    <name>A0A2S9GXA7_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Nicotinate-nucleotide diphosphorylase (carboxylating)</fullName>
            <ecNumber evidence="4">2.4.2.19</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Quinolinate phosphoribosyltransferase [decarboxylating]</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">S2091_3000</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in the catabolism of quinolinic acid (QA).</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; NAD(+) biosynthesis; nicotinate D-ribonucleotide from quinolinate: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the NadC/ModD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.19" evidence="4"/>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92341">
        <property type="protein sequence ID" value="PRC92341"/>
        <property type="gene ID" value="S2091_3000"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00253">
        <property type="reaction ID" value="UER00331"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004514">
        <property type="term" value="F:nicotinate-nucleotide diphosphorylase (carboxylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009435">
        <property type="term" value="P:NAD biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01572">
        <property type="entry name" value="QPRTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004393">
        <property type="entry name" value="NadC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027277">
        <property type="entry name" value="NadC/ModD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036068">
        <property type="entry name" value="Nicotinate_pribotase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037128">
        <property type="entry name" value="Quinolinate_PRibosylTase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002638">
        <property type="entry name" value="Quinolinate_PRibosylTrfase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022412">
        <property type="entry name" value="Quinolinate_PRibosylTrfase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32179">
        <property type="entry name" value="PTHR32179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01729">
        <property type="entry name" value="QRPTase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02749">
        <property type="entry name" value="QRPTase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006250">
        <property type="entry name" value="NadC_ModD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51690">
        <property type="entry name" value="SSF51690"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00078">
        <property type="entry name" value="nadC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-0662">Pyridine nucleotide biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="QRPTase_N" evidence="11">
        <location>
            <begin position="41"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="domain" description="QRPTase_C" evidence="10">
        <location>
            <begin position="131"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009400"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00033102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR006250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PRC92341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="299" mass="31506" checksum="C7103008764426AC" modified="2018-07-18" version="1">MTSSNLLTNSSTNLSNPFAPFDAALAAAFEANIQTALAEDIGSGDLTGLLVPDAAWVEARVLVREAAVLCGAPWFEAVMLRCHPEVRIHWHYAEGDLMRADSQVCQIHAPARALLTAERSALNFLQLLSGVASATRRYVNLVEGCKAAILDTRKTVPGMRLAQKYAVRVGGGQNQRLALYDGILIKENHIAAAGGITQAMAAAKALNAGVTIQVEVESIAELDEALVAGAVSILLDNFDLATMREAVVMSAGRAVLEASGGINVSSVRAIAETGVDRISIGSLTKDIQAIDFSLRVIAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXE9</accession>
    <name>A0A2S9GXE9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">YCII-related domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2995</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the YciI family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92336">
        <property type="protein sequence ID" value="PRC92336"/>
        <property type="gene ID" value="S2091_2995"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005545">
        <property type="entry name" value="YCII"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03795">
        <property type="entry name" value="YCII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YCII" evidence="2">
        <location>
            <begin position="10"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="96" mass="10775" checksum="37FD6881707072A8" modified="2018-07-18" version="1">MFLLNISYIKSLDQVEPQMKAHGEWVMRYLNEGIFLFGGPKKSGMGGVIGVKSIEKQQLMSILAEDSFVQADVAEYQIMDFNCKLADVKLESLKLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXI7</accession>
    <name>A0A2S9GXI7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">P-loop containing region of AAA domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2795</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92420">
        <property type="protein sequence ID" value="PRC92420"/>
        <property type="gene ID" value="S2091_2795"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="195"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="263"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="350"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="706"/>
            <end position="733"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="943" mass="106898" checksum="0A0A62988E77ECDC" modified="2018-07-18" version="1">MFHIKSLELVHWDYWQRIKNIPLDAKIITISGQNGSGKTTLLDALRTLFGLDCSMGRTYKHYARHSGQPIAWLRAVVDNKPVGRQLSNRPFRSSGFFSEDEVTLFCQIQKNGGDWKRQYLMRPGCVEIEEVVGATDWLGVETYRKRLASAGLSPAMAKVLALEQGETDKLCEYAPRQLLDLVFQVFGDKEVLDAYDEAKQHQHDTELELQQFEAELDIAQSHLEGLRLRVANYHQWDNKNSERRDLQEQILPSLQYFETKKHYSNISQSLRSAKQNAQQQDQQLSAQRAELAEKGRQFTANLQQEGTLEQEEKALQKRLSEINTQLKPQENLLEQKQRLEKLTAVSGTDIAEITQQLEQQETQLAQQKQQRAQLTEKISEQQSTIAALQSKTGLPDPENVRSMRRTMADAKIAHVMLADVVEVSEPRWQGAVEGVLKSFSYVMLLENASDAPAAFKLAEQQRYPHFIVPERVAAPKINGKQDASLLAVVQFSAPVPSWLIDQLKRIQRVDTVAQGMQMSGAEEWITPEAFHSERRGGRSLFVDVARYRFGQAGRAQRLDALQKSCLKLEQQEDQLTLDISKLASNVSNLKTRLAGVDAAKELHARIDEFAEASRNVVPLKKLRTEVGSRLGELGDLLKQATVAKTRSEIAWQEAQKHLSVSEQHCRNNEQKLAQERSAQAQVLKDSRHTWSKLPAGWRKSGYLNSLVEKYDNARQVELRLKSLQQDILSEEWETDATVVDQHHRLHHQLAGQQAETEERRYQNNRAMEATSNARGAYIERLRYTIKIYAKNIKQLGELAGIEVHADPVRLENDDVQLAQAGLHVKFKFDGKGVIGMNDGEASGGQQVMKSLILLIGLLKSEEGSGGFVFIDEPFAHLDIRNIQLVGEFLKNTDAQYLMTTPLTHNTDVYDPSELTLITSKKKKEMEWAQPIFVLQRRPQGAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GY09</accession>
    <name>A0A2S9GY09_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2645</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92590">
        <property type="protein sequence ID" value="PRC92590"/>
        <property type="gene ID" value="S2091_2645"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="197" mass="22577" checksum="AFF6C7F71AA7D2C1" modified="2018-07-18" version="1">MKSQAKSSLTLPVHYFEQQQDWAAWLLENHSTSPGLWLKLAKKGSDVKSVSYGEALEIALCFGWIDGQKQAHSEQFWFQKFTRRSSKSMWSKINKEKVLVLIEAGSMHAAGLSEIERAKSDGRWESAYDPASTATVPDDLQSALDSNARARDFFETLDKTNRYAVLFRIQTAKKAETRARRILQFVQMLERHEKLHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GY71</accession>
    <name>A0A2S9GY71_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2727</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92672">
        <property type="protein sequence ID" value="PRC92672"/>
        <property type="gene ID" value="S2091_2727"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="125" mass="13420" checksum="BB69CD66DBA97853" modified="2018-07-18" version="1">MSFYADAANTADKLLKKYGQTAILRVLTPVVYDPTSIVPSSAATTDYPVTVALFDYTWRQGGLSTTANTMIEAGDKEIYMSAVGLTLIPQPENQVIAGGQTWTIKSVKQVNPAGTAVIYTLQGRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYE1</accession>
    <name>A0A2S9GYE1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2731</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92676">
        <property type="protein sequence ID" value="PRC92676"/>
        <property type="gene ID" value="S2091_2731"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="141" mass="15687" checksum="AA8A91CA34B66DEF" modified="2018-07-18" version="1">MSAKNAEVKKVSMSLNDLNIVKKCDDAFEFEYISETTGKGTGVFINVLGSHSPKVQGYVRRELNDLRKQAEMAKKRGKEIERSIEDDEGFSNEAAAIRVIGWRGITEDYSPELAVQLIASNPIIRAQIYAASNDLENFTKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYH6</accession>
    <name>A0A2S9GYH6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative motility protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2480</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92750">
        <property type="protein sequence ID" value="PRC92750"/>
        <property type="gene ID" value="S2091_2480"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025906">
        <property type="entry name" value="YjfB_motility"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14070">
        <property type="entry name" value="YjfB_motility"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="67" mass="6781" checksum="49B165A49C50A195" modified="2018-07-18" version="1">MDLAAVANGTSNNISDAGVSQTVALDVLKQALNIDQESATALIQAIPQSPTVPNLPANLGNHVNTTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYS0</accession>
    <name>A0A2S9GYS0_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ribosome maturation factor RimP</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rimP</name>
        <name evidence="6" type="ORF">S2091_2292</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Required for maturation of 30S ribosomal subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RimP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92875">
        <property type="protein sequence ID" value="PRC92875"/>
        <property type="gene ID" value="S2091_2292"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042274">
        <property type="term" value="P:ribosomal small subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01734">
        <property type="entry name" value="YlxS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01077">
        <property type="entry name" value="RimP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003728">
        <property type="entry name" value="Ribosome_maturation_RimP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028998">
        <property type="entry name" value="RimP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036847">
        <property type="entry name" value="RimP_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028989">
        <property type="entry name" value="RimP_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035956">
        <property type="entry name" value="RimP_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33867">
        <property type="entry name" value="PTHR33867"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02576">
        <property type="entry name" value="DUF150"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17384">
        <property type="entry name" value="DUF150_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74942">
        <property type="entry name" value="SSF74942"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75420">
        <property type="entry name" value="SSF75420"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="DUF150" evidence="4">
        <location>
            <begin position="6"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="domain" description="DUF150_C" evidence="5">
        <location>
            <begin position="82"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF17384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC92875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="161" mass="18232" checksum="2F6010FFCC691F81" modified="2018-07-18" version="1">MYLHTLIEKTVTGLGYELVEYELAARGLLRVYIDFTFEQADRGQITVEDCATVSHQLSHVLTVENANYERLEVSSPGLDRALTKLSDYVRFVDREAIIKLRLPMAGTPNRKTYQGIIHAPVGEALMLEFENKDGVAMLEFTLADVEKARLVPQVDFRSRKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYS5</accession>
    <name>A0A2S9GYS5_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Type II secretion system core protein G</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">S2091_2275</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the GSP G family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92858">
        <property type="protein sequence ID" value="PRC92858"/>
        <property type="gene ID" value="S2091_2275"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015627">
        <property type="term" value="C:type II protein secretion system complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015628">
        <property type="term" value="P:protein secretion by the type II secretion system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000983">
        <property type="entry name" value="Bac_GSPG_pilin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013545">
        <property type="entry name" value="T2SS_protein-GspG_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010054">
        <property type="entry name" value="Type2_sec_GspG"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08334">
        <property type="entry name" value="T2SSG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00813">
        <property type="entry name" value="BCTERIALGSPG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01710">
        <property type="entry name" value="typeII_sec_gspG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="61"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="T2SSG" evidence="11">
        <location>
            <begin position="84"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004377"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF08334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PRC92858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="194" mass="21208" checksum="50FF9FDA66191E6F" modified="2018-07-18" version="1">MSLNSSNKHNVVKLFQFSPSAIRKYHSTCNTIIVPTFIDIIDMQNSVSLLKRVRKPLARGFTLIEIMVVIAILGIMAAVVVPKLVGHTDTAKIAAAKQDIANIKQALILYKLDNQRYPTTEQGLQALVAKPTTGPAANGWKSDGYLEKLPKDPWQNPYQYLSPGIHGEFDVFSYGADGQPGGDGINADIGSWDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYW6</accession>
    <name>A0A2S9GYW6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Transposase domain (DUF772)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_2341</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in the transposition of the insertion sequence IS5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the transposase 11 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92924">
        <property type="protein sequence ID" value="PRC92924"/>
        <property type="gene ID" value="S2091_2341"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002559">
        <property type="entry name" value="Transposase_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008490">
        <property type="entry name" value="Transposase_InsH_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01609">
        <property type="entry name" value="DDE_Tnp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05598">
        <property type="entry name" value="DUF772"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0814">Transposable element</keyword>
    <keyword evidence="4" id="KW-0815">Transposition</keyword>
    <feature type="domain" description="DUF772" evidence="7">
        <location>
            <begin position="56"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="DDE_Tnp_1" evidence="6">
        <location>
            <begin position="232"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="218"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="222"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF05598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC92924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="423" mass="47712" checksum="6845F18EB33FE8C6" modified="2018-07-18" version="1">MKRFIQGEHRTQSTLLQEVLDDYVTEENPVRVVDVFVDNLNLQALGFEGVTPAVTGRPSYHPAVLLKLYVYGYLNRIQSSLRLEREAQRNIELMWLTGRLTPDFKTIANFRKDNGTAIRNVCRQFVAVCQKLDLFAESLVTIDGSKFKAVNNRDKNFTKGKVEYRMKEIESSINQYLTELDTADRHEPEIKQARTERLHQKIAKLQTQMKQLAHIKEQLDDAPDNQLSQTDPDARSMRTRGSGIVGYNVQTAVDTKHHLIVAHEVSNDGNDRDQLFNMATQARDAMGVKELTAIGDRGYYKNTEILACDQANIKAIVAKSVTSNATSDGRFGKDDFIYDASNDVYRCPAGQQLIKRMTVVERGITSHKYWASGCKTCPLKSQCTPSPQRRAAWIISRKRCASAAKQLSTPSARSNSGWARSTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZA3</accession>
    <name>A0A2S9GZA3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2119</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93033">
        <property type="protein sequence ID" value="PRC93033"/>
        <property type="gene ID" value="S2091_2119"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.720.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018668">
        <property type="entry name" value="DNA-binding_VF530-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036361">
        <property type="entry name" value="SAP_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09905">
        <property type="entry name" value="VF530"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="73" mass="8537" checksum="D3A4366DBEFA95E3" modified="2018-07-18" version="1">MTHPNNPLQGVTLEHILTELVRVYGWEEMAKEVNIRCFTHEPSVQSSLKFLRRTPWARDKVEAMYVAIKKTNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZK5</accession>
    <name>A0A2S9GZK5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2255</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93169">
        <property type="protein sequence ID" value="PRC93169"/>
        <property type="gene ID" value="S2091_2255"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="70" mass="7806" checksum="818A1A10912E1135" modified="2018-07-18" version="1">MNKPARILTFKCKKCAKPVQVFLQKVSACSHIQPYQGICKCGELHRHATGQADAVTSFINSADSDWSHHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZP6</accession>
    <name>A0A2S9GZP6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2273</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93187">
        <property type="protein sequence ID" value="PRC93187"/>
        <property type="gene ID" value="S2091_2273"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015771160" evidence="1">
        <location>
            <begin position="23"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="181" mass="19788" checksum="D275C2D3206CB8F6" modified="2018-07-18" version="1">MRNIFGLMLTIAVLQFSVPVFSASTNPKARYIATTEKAESDYKLARARCDRMADIAKNLCVAQAKAAQTQTESNATAVYKDTPEARFIARIDIADVNFEVKKAMCESRHGNPREECVKDAEATMVAEKQNAAAVKKIGEATSSPNDDRLATNYIAAIKKCDALNGVQKDDCAKSTKKQFGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZU2</accession>
    <name>A0A2S9GZU2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative hydrolases or acyltransferases (Alpha/beta hydrolase superfamily)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1956</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93218">
        <property type="protein sequence ID" value="PRC93218"/>
        <property type="gene ID" value="S2091_1956"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="48"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="283" mass="29665" checksum="4D9C193FCEB2FA78" modified="2018-07-18" version="1">METLTAPTVSGHSATHFEEQLDAALVMNALLNTDGRAAISDKGTGRAILVLHGGGGVSTVFGLSQALVAQARVILPTHPGFDGTPRPAHLASVTELAHFYLTLLEKLGLDDVVVIGSSIGGWIAAEMAVINASRIKGLILLNSVGIQVPGETLTDVSRLTPPELIRLASHNPELILRNMPPPTAERQAIQAANAASLAAYTKSTSMMAPGLREKLALVAVPVLVLWGESDGIAAPNYGKAYAEAFAKGKFELITEAGHLPQIEQPARVLAHIENFISELDSAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZY9</accession>
    <name>A0A2S9GZY9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Plasmid replication region DNA-binding N-term</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2272</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93186">
        <property type="protein sequence ID" value="PRC93186"/>
        <property type="gene ID" value="S2091_2272"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021104">
        <property type="entry name" value="KfrA_DNA-bd_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11740">
        <property type="entry name" value="KfrA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="KfrA_N" evidence="2">
        <location>
            <begin position="32"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="116"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="310"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF11740"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="351" mass="39314" checksum="C7D2D21DCDA56146" modified="2018-07-18" version="1">METSIANEKQLLADIELLREQFQQTQELYREVCALLFFRYGITPTANKLYQLVRKGSMSAPAEALGKFWEDMREKSRVRIEHPDLPDALKTAAGELTATLWVSAQTLANDSLATYRSEAQAQVTEAKATAETAETESRITREALEKAEGELNAAHNRISVLNQDLAAAMATNASLELQLHQSRTDNLAQQQLLVDARRDFTAELEKLRAAAQLADERVRASEIRALLEIDRERSTSSKLQKDLDTTRTTAAQLNERMQSEITNLQAQLGDIRQNTGIVEGKLQSALAGRDVIANDLKIAQVQLADIGTQLSDARNDSENWRRNAEDLQRAITELKNETPKLTRAFRRVKAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H054</accession>
    <name>A0A2S9H054_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Metallo-beta-lactamase superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2085</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93347">
        <property type="protein sequence ID" value="PRC93347"/>
        <property type="gene ID" value="S2091_2085"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lactamase_B" evidence="1">
        <location>
            <begin position="42"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="346" mass="39122" checksum="A1C2B919F42DA7DF" modified="2018-07-18" version="1">MNPLETQLSYPFEDTLPKPGDIQRVCAGVYWLPMGLPFALNHINLWLLEDDNGWTIIDCGISNDDTKANWEIIFALHLNGKPVTRVIATHCHPDHLGLADWLCERWQVSLWMSAGEYSFGRMMQAGLSGVEGSSTVPHFQRHGVTDPALVEQLLGRKNYYPTLVPSVPTAYVRMQEHQLIHIGAHHWRVITGFGHSPEHVSLYCDELRCLISGDMLLPRISTNVSVWAIEPYANPVQQFLDSLDKYCDLESDTLVLPSHGKPFKGIHIRVQQLIDHHHARLAEVLVACVTPQSANDIVPIMFLRPLDTHQLTFALGEALAHLHLLWFAGKLQRKLGEDGIYRFVRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H058</accession>
    <name>A0A2S9H058_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">2-hydroxychromene-2-carboxylate isomerase</fullName>
            <ecNumber evidence="1">5.99.1.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_2076</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>2-hydroxychromene-2-carboxylate = (3E)-4-(2-hydroxyphenyl)-2-oxobut-3-enoate</text>
            <dbReference type="Rhea" id="RHEA:27401"/>
            <dbReference type="ChEBI" id="CHEBI:59350"/>
            <dbReference type="ChEBI" id="CHEBI:59353"/>
            <dbReference type="EC" id="5.99.1.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the GST superfamily. NadH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.99.1.4" evidence="1"/>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93338">
        <property type="protein sequence ID" value="PRC93338"/>
        <property type="gene ID" value="S2091_2076"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018845">
        <property type="term" value="F:2-hydroxychromene-2-carboxylate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901170">
        <property type="term" value="P:naphthalene catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03022">
        <property type="entry name" value="DsbA_HCCA_Iso"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001853">
        <property type="entry name" value="DSBA-like_thioredoxin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014440">
        <property type="entry name" value="HCCAis_GSTk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044087">
        <property type="entry name" value="NahD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01323">
        <property type="entry name" value="DSBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006386">
        <property type="entry name" value="HCCAis_GSTk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DSBA" evidence="3">
        <location>
            <begin position="4"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="2">
        <location>
            <position position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR006386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR006386-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC93338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="201" mass="22451" checksum="7F2C1AEFA524367A" modified="2018-07-18" version="1">MSSTIHFYFDFTSPYGYLAAMRIDQLAAKYAQQVEWHPILLGVIFKTTGTLPLVDVPLKGTYSLHDLKRSARFHAIPFQQPEHFPISTQNTARAMLWIANKLGEDSAIKFAKAAYQAYFVDGINIGEIEHVVQIANRLGFDGDTLANEISSPEIKAQLKAEVDAAQEQGVFGAPFVIIDGEPFWGFDRFDQIEALLKNGQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H061</accession>
    <name>A0A2S9H061_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1761</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93374">
        <property type="protein sequence ID" value="PRC93374"/>
        <property type="gene ID" value="S2091_1761"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025528">
        <property type="entry name" value="BrnA_antitoxin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14384">
        <property type="entry name" value="BrnA_antitoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="89" mass="10400" checksum="819D5D103D18C0F7" modified="2018-07-18" version="1">MNKIPESLRKELAALAAKSEHEIDFSDIPATKQEEWDGAVRGKFYRPIKQQLTVRIDSDVLEWLKSQGKGYQSRLNDILRTEMLNKLRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H087</accession>
    <name>A0A2S9H087_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_1755</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPF0324 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93368">
        <property type="protein sequence ID" value="PRC93368"/>
        <property type="gene ID" value="S2091_1755"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004630">
        <property type="entry name" value="UPF0324_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018383">
        <property type="entry name" value="UPF0324_pro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30106">
        <property type="entry name" value="PTHR30106"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03601">
        <property type="entry name" value="Cons_hypoth698"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00698">
        <property type="entry name" value="TIGR00698"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="41"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="94"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="131"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="160"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="232"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="278"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="302"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="335"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC93368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="359" mass="38054" checksum="3C4734C20D5F845F" modified="2018-07-18" version="1">MLPARYKSLNPGLIPGLILCGVIAFLASFMGDIDFLQSHGFSALTIAIILGMVLGNTWYKKVEPTFMAGVGLSKHNLLRFGIILYGFRLTLQDIAGVGVAGIASDVLVLGSTFLLALFIGIKLFKLNPESVILIGAGSSICGAAAIMASDGVVEAEPEQVSVAVSTVVVFGSIAIFLYPYLYQLNLDWHWLATSANAFGIYAGSTIHEVAQVVAAGRSINPAVEDVAVITKMVRVMMLAPFLLMLSLYFARKSAANGASNVASADADTPGKPKLAIPWFAFLFIGMAVVNSLHILPAQLTHVLVQIDTILLAMAMAALGLTTHLSAVRKAGAKPLLLALILFVWLIIGGALISRLVFWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0D7</accession>
    <name>A0A2S9H0D7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1824</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93437">
        <property type="protein sequence ID" value="PRC93437"/>
        <property type="gene ID" value="S2091_1824"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="154" mass="17473" checksum="44A643C09B73FF5E" modified="2018-07-18" version="1">MKYISKGGRSLCYYTLRVNGKWMLNMNRYFFSLMLCILLSLVLGCSKPDQVKTIKSPTDGIFYTVEIYHEHSPVADGTRVYANLERHGKVERMLVLEGGDLTITDINWNGPYDATLCLNGGITDTFRNEVTLISGDTAVTIHNYLHENCNIQKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0F0</accession>
    <name>A0A2S9H0F0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1846</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93459">
        <property type="protein sequence ID" value="PRC93459"/>
        <property type="gene ID" value="S2091_1846"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="101" mass="11330" checksum="BAEAE4789536152B" modified="2018-07-18" version="1">MTSINQQHTQQGPPLITHLAIDTIDAYTQARDIVSDFSAIFEVLDHLALEGLCSDRISRILFRAGYSHATEQLKFLDEKISDAYKTLDELKADSDHTSHAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0M4</accession>
    <name>A0A2S9H0M4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Exosortase A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">S2091_1922</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93535">
        <property type="protein sequence ID" value="PRC93535"/>
        <property type="gene ID" value="S2091_1922"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013426">
        <property type="entry name" value="EpsH-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026392">
        <property type="entry name" value="Exo/Archaeosortase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019127">
        <property type="entry name" value="Exosortase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017540">
        <property type="entry name" value="Exosortase-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014263">
        <property type="entry name" value="Methanolan_biosynth_EpsI"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11984">
        <property type="entry name" value="DUF3485"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09721">
        <property type="entry name" value="Exosortase_EpsH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02602">
        <property type="entry name" value="8TM_EpsH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02914">
        <property type="entry name" value="EpsI_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04178">
        <property type="entry name" value="exo_archaeo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03109">
        <property type="entry name" value="exosortase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="49"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="77"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="107"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="190"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="216"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="256"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="298"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="domain" description="DUF3485" evidence="10">
        <location>
            <begin position="310"/>
            <end position="509"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF11984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC93535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="518" mass="57964" checksum="D992D1CC79260BD7" modified="2018-07-18" version="1">MDAAIKIEANYWKILAKGLAIVAAFIAPFLIYFSTTTSIISIWNSSETFAHGYIILPISLWLIWRRRQALALLPIQPFWPGLALILVAGAGWMLADLGDVQVVRQYSFVALLPLTVLVILGWRMALTMAFPLCFLMLAVPFGDVFIEPLINFTADFTVAALQMTGIPVLRNGTSFSLPSGNWQVAEACSGVRYLISSFTLGCLYAYLTYHSWKKQLIFVVMAIIVPIFANGVRAYLIVMLGHLSGMTLAVGVDHIIYGWLFFGLVMFLMFWIGNYWRDDNDKAGSAMAINHLTGTAGATTYQVMAATAAVIICLAIWPLYANYITRANHNPVIARLDNFQSDWPKTSSFTDWSPSYLPDSTELNQSYAKDGHQINLLVKYYRNQTHDTALISSNNRMIRDGEELWIKTSTITRDEKFNGINLGAARTLSVSEAQIKSSSEHLLVWSWNWISGQFIVNNYLGKILQTRDKLRIAGDDGAAVILSAPYTENPEEARLVLRRFLSTNLDRIEATLNANRKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0M8</accession>
    <name>A0A2S9H0M8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative secretion ATPase, PEP-CTERM locus subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1918</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93531">
        <property type="protein sequence ID" value="PRC93531"/>
        <property type="gene ID" value="S2091_1918"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017466">
        <property type="entry name" value="ATPase_secr-sys_PEP-CTERM_pred"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13401">
        <property type="entry name" value="AAA_22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03015">
        <property type="entry name" value="pepcterm_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="1">
        <location>
            <begin position="42"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="332" mass="37570" checksum="690F26228D787699" modified="2018-07-18" version="1">MYETFYGFNAKPFQLKPDPRFFFGSKGHNRAMAYLEYGISQGEGFIVITGEIGAGKTTLMRNLFCELKSENIVAAQIVNTHVGSDDILRLVAAAFGLEYENATKATLLHRVEQFLKQCDRQGKRALLVVDEAQNLTPRAVEELRMLSNFYTEDKSLLQTFLLGQPEFRRVLLSEDMEQLLQRVIASYHLGPLDIGETQSYIEHRLQTVGWKGNPTISTEAFSAIYSYTGGIPRKINSLCDRMFLMGYIEELQAFDESEVNQVIADIKQEFKLPPEKVEIPVNLTALGLKDSYAYSNAENMDDRMARMERSISSVIDALKKMLPSSKMNNSPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0P4</accession>
    <name>A0A2S9H0P4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Sulfotransferase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1550</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93549">
        <property type="protein sequence ID" value="PRC93549"/>
        <property type="gene ID" value="S2091_1550"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008146">
        <property type="term" value="F:sulfotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000863">
        <property type="entry name" value="Sulfotransferase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00685">
        <property type="entry name" value="Sulfotransfer_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Sulfotransfer_1" evidence="1">
        <location>
            <begin position="9"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="671" mass="75843" checksum="BCB5FC9F7B60FBA7" modified="2018-07-18" version="1">MEKLDKKLIVVLGMHRSGTSAITRGLSVLGVDLGDRIMPGVEGINSKGFWEDIDLNALNIEMLNAINSDWNCLEQLEQIDVEFLTKQNYLLRAVALLRDKIGTKSVFGFKDPRVAKLLPFWKIVFDYCSLDVSYVFAVRNPLSVVQSLVKRDGFEREHSYLLWLSYVVTSLLGCIDSKRVLVDYDLLMQMPDQELNRLADYLGLKVDQKKLQNYVSEFLDPKLRHTTYQISDLLLDGSCPSLVSEIYCSLFEVASGKSKFEDNVLIFKIEKWSKELLHSKPQLRLVDKLLKQNRQKTIENHNQTLCISEVKSELVLRTQHVAGLEQTITDQANHVQGVESELSSRTRHVAGLEQTITDQVHHIQGVESELSSRARHIAGLEQTITDQAHHIQGLESELSSRARHIAGLEQTITDQANHVQGVESELSSRTRHVAGLEQTITDQVHHIHGVESELSSRVRHIAGLEQTITDQANHIQGVESELSSRTLHIAGLEQTITDQAHHIQGVESELSLRAQHIAGLEETVTDQANHIQGVESELSSREQQVACLEQTITDQTHHIQGVESELSSRTQHIAGLEKTITDKAKHIHEVESELSSRVKQISNLDLTLKDKNDHILSCDKEHTLLRAHISDLEMTNKSQMTRIQLIEVELERCQNTVFENIAKRISTLFKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0T2</accession>
    <name>A0A2S9H0T2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1564</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93563">
        <property type="protein sequence ID" value="PRC93563"/>
        <property type="gene ID" value="S2091_1564"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03360">
        <property type="entry name" value="LbH_AT_putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020019">
        <property type="entry name" value="Sia_OAcTrfase_NeuD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03570">
        <property type="entry name" value="NeuD_NnaD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="221" mass="24289" checksum="C86D1209E767E06A" modified="2018-07-18" version="1">MKKSLVIFGVGDIAQLAHFYFNSDSEYQVVAFTVDAAYLTKTNFCGLPVIAFEKIGEHYTPDNYEVFVALSYSKLNAIRKEKYLLAKALGYRIASYISSRATVLNEGRIGENCFIFEDNTIQPFVNIGNNVTLWSGNHIGHHSIIKDHCFIASHVVISGGVEIGEQCFVGVNATLRDHIKVGEKCVIGAGALLLSNADPEGVYIGLETNRSKVPSTRLSHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0W5</accession>
    <name>A0A2S9H0W5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1608</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93607">
        <property type="protein sequence ID" value="PRC93607"/>
        <property type="gene ID" value="S2091_1608"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="75" mass="8975" checksum="64C1838D7041381A" modified="2018-07-18" version="1">MMTYEEYLDEVTTLMTEFFDLTDAQAIKYVMRAQAGDFFTLHDDHPEMCTLERAQLDARTIYEQRNKSRPDIFKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0Z8</accession>
    <name>A0A2S9H0Z8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Stp2: sugar transferase, PEP-CTERM/EpsH1 system associated</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1923</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93536">
        <property type="protein sequence ID" value="PRC93536"/>
        <property type="gene ID" value="S2091_1923"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017522">
        <property type="entry name" value="Sugar_tfrase_PEP-CTERM_Stp2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03088">
        <property type="entry name" value="stp2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="2">
        <location>
            <begin position="20"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="196"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="395" mass="43734" checksum="822B91EEDF36ADF1" modified="2018-07-18" version="1">MSAIINPAPLVVHLIFRLDFGGLETLLVECVNHIPPNRYRHAIICLTDFTEFSNKITQPGVEIYALHKPPGLGFDIHIALWKLLRKLRPTILHTYNLATIEYTFTAALAGVPIRIHAEHGRDMADPEGKNTKHNFLRRHLAPLIDRYVPVSSDLQQWLTKVVRIPVAKQLLINNGVDTEKFQPNKSVSIPASPWTSEHLVIGTVGRIQDIKNHSGLVRSFQRLQQLLPQHKDRLRLSIIGDGPLLPTLKMQVEAAGLSNVVWLPGARADVTELMHSFTLFTLPSLAEGTPVTLLEAMACGLPVVASHVGGIPEVISDQIHGSLVPAADEEALANALANYIKQPELATRHGAAACIRIEQKYSLTSMLNAYTNLYDVLCKEKFKHVPLAHVIPRAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H129</accession>
    <name>A0A2S9H129_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1695</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93694">
        <property type="protein sequence ID" value="PRC93694"/>
        <property type="gene ID" value="S2091_1695"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="40"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="222" mass="25307" checksum="CB9B3B178C037961" modified="2018-07-18" version="1">MENKAENKVNEKVSDTMTNPVNKSANEHTPQQIHRGRWKLYLVIAICASPLFFSYLTYYVIKPTGRTNYGTLLDPRLYPMPKLDSQLQGSGAQELDAYKGKWIMLQVSASDCQAACKKSLLNMRQLRLMQGKDMDRIERVLVITDQNPMETSLLREYDGTHVLRADAKNVEAWLPAEQGSTMQDRLYLIDPLGNLMMRYSVDADPYKIKKDLDKLLKASSIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H153</accession>
    <name>A0A2S9H153_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1712</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93711">
        <property type="protein sequence ID" value="PRC93711"/>
        <property type="gene ID" value="S2091_1712"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015562">
        <property type="term" value="F:efflux transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003423">
        <property type="entry name" value="OMP_efflux"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010131">
        <property type="entry name" value="RND_efflux_OM_lipoprot_NodT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02321">
        <property type="entry name" value="OEP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01845">
        <property type="entry name" value="outer_NodT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0564">Palmitate</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1134">Transmembrane beta strand</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU362097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="495" mass="52739" checksum="C4FF4F1AC94B9DB0" modified="2018-07-18" version="1">MKNQSNSLFRPFFRPSPISLAIACIALVSGCAVGPDYMRPNTALPTQHTEQALDVAAAPEGEVTQKFVAGQDIPAQWWELFHSASLNELIQDSLKNSPNIQAAQAALRAAQENVAAQQGAYFPTLSAQFTPTRQHVASALASPASSNASIYNLHTAQLSISYVPDVFGLNRRQVESLQAQADMQSYQLQAAYLTLTSNLANAAITEASLRAQLAALNDVLTAQQKILEMVQRQFKLGQLGELDMAAQESAVANAQAAIAPVQKQLAQQRDLIKALAGRFPNDSTAAQFELASLQLPGEIPLTLPSTLVDHRPDILAAEAQLQSASAAVGVAIANRLPNITLGVDSYGSAAYTLANLFKSSTTFWNLAGSVVQPIFDGGTLKHKQGAAQAAYEQAEAQYRSTVISAFQNVADALQAIQADALALHAAKNAEMAANKTLVIAQKQLALGDISPSSMLTIEQNYQQAKLALVQTQAMRYADTVALFQALGGGWWNAKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1A6</accession>
    <name>A0A2S9H1A6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Periplasmic binding protein domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1724</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93723">
        <property type="protein sequence ID" value="PRC93723"/>
        <property type="gene ID" value="S2091_1724"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025997">
        <property type="entry name" value="SBP_2_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13407">
        <property type="entry name" value="Peripla_BP_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015491175" evidence="1">
        <location>
            <begin position="25"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="domain" description="Peripla_BP_4" evidence="2">
        <location>
            <begin position="65"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="369" mass="39779" checksum="38FA8F561AA48752" modified="2018-07-18" version="1">MIQRKFNIVLGVLAMLLFGSTALAQENAMQAMGKANAKVAKAASHKNHWDGPTDGPKLQNKKRVVFIAGDMVNTVVAELYKGTKEAAAMAGWEVLLIDCRAACYQGAPVINQALAMKPDGIILAGVDAQSQAKGLDKAQEKKIPVVGWHAIAKPGPVDGLFANVGNNPRESAQIAALYGVTEVNSKMGMVIFTDNSTPYLSAKSSALIEIIKQCDICRLLSVEEMPVSDASAKMQQTVDDLVKHYGSKWTHVIAVSDVYFDVMEKPAIAALIAGNKLKGLSAGDGSVTSYQRIHANNVQIGTVPEPANMQGWQLVDELNRAFSGVAASGYSMPVHLATNQNIPFDGGDKNVFEPDNDYRNQYRKYWVAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1H4</accession>
    <name>A0A2S9H1H4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ABC-type branched-chain amino acid transport system permease component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_1717</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93716">
        <property type="protein sequence ID" value="PRC93716"/>
        <property type="gene ID" value="S2091_1717"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015658">
        <property type="term" value="F:branched-chain amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06581">
        <property type="entry name" value="TM_PBP1_LivM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001851">
        <property type="entry name" value="ABC_transp_permease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043428">
        <property type="entry name" value="LivM-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30482">
        <property type="entry name" value="PTHR30482"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02653">
        <property type="entry name" value="BPD_transp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="34"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="81"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="109"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="159"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="210"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="246"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="283"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC93716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="332" mass="36404" checksum="80E7A59380597BDD" modified="2018-07-18" version="1">MKNIIHFRTTLLIIATVLILPLTLDSGTLATEVLIFSLAALGCNLLLGYTGLMSFGQGIFLGVGSYATGLSLLHWQLPVLLALLLTMLIGALVALLVGWFSIRQRGTYFVMLTLAFSQMFYFLAYTMTSVTGGDNGLLNIPRPSLSVFGIELLATATPWQYYSFVALIFVLVFFLLQRVVDSVLGRTLLSIRDNEARATAIGYDIRQFKLAAFIISGAITGLAGGLHAMMTGIAPLTNIEYHISESILIMTVIGGTGNLFASVLGAAFYVLMGDWLSELWPRWLMLLGFLLIAISLYLQQGLFGFSKSLIQQITNRFRPDRAPDNAKQEKHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H237</accession>
    <name>A0A2S9H237_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Calcineurin-like phosphoesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1212</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94039">
        <property type="protein sequence ID" value="PRC94039"/>
        <property type="gene ID" value="S2091_1212"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP_ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallophos" evidence="1">
        <location>
            <begin position="5"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="1020" mass="117811" checksum="A596445C9F2DF1C9" modified="2018-07-18" version="1">MKIVILHLSDIHFKQSDNPIENQLQLISNAVKTIEPNAEDLSILVTGDIANTGNENEYIKASIFFKALEARIRELQNFKNITWCFSPGNHDCDFSNPSKIRSELLEMQKKHSVPSIDDEILECLLKPQKNFRKFVDECHPKHSIDRHYYSASTIYLGNDKINIHNYNTAISSSITETQGDLFFPISQLPSIESAAEIVISCFHHPYNWLESNNAREFRKHVESTSDLILSGHEHVPGHYNKTDLLSKTNSTYFEGAVLQNHKNPSESGFNAFVLDIERKLIKTFVFNLSEGLYRANTNNPDWIEFQRNKNRVRNEFEINSSYIDRFLADPGAGFTNSRKGKLEFQDIFVPGYLDEISRLDESKDLVIPAVPMANFTKSSANKNRILIIGEEQSGKTSFAKYLYMSYHESGLIPIFMRASMLKDRDIEDTHFRNRLFEAISDQYSPDLQETFLQLPIEKKVLLLDDLHLSPFNQKGLGRFIEHIENQFGKIILFSHALSFVDELANAATKNDFAHFSQYEVKPFGNQLREQLIERWYLIGKEYTVNELELEKMVVNTKRTVDGLLGKNLLPSYPIFILIILQQLEASTNLNTYNGAHGYLYELLITSAITNANTKIDLDTAYTFLGMLAESMFQRKTRFVTKEEISEIHKEFCEFSKQTIRLEKIEKPLLDANILIEHDQKYWFRYKYCYYYFAARFLSDRLRTETGQARLSLLGGEIYREEYANILMFLAYLSNKDQSIIDVMLRNAKSIYVGVAACDFDEHIKFINKMHADLPKSILLDRKTSHSRAEINQRLDEFDHVNGSLQKQNEDVDDALKLNVALKTIQVLGQLLKNFPSSLDGNIKKEIADQCYQLGLRTMTKFFQFAEENQEGLITLFDDWLGNVTAKETEISLKPKAEQFIAFLIEAFSTVVIRRVSSAVGVASLAPLYEEIRNQYSGLSVNMIDYAIKLDHFERFPLEEIDAIIKEAKNNIFPLILLRRLTIEHFQRFPVDRKVKQSACTKLKIELKYMQLLENKQKKMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H265</accession>
    <name>A0A2S9H265_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltransferase domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1220</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94047">
        <property type="protein sequence ID" value="PRC94047"/>
        <property type="gene ID" value="S2091_1220"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_11" evidence="1">
        <location>
            <begin position="49"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="219" mass="24492" checksum="C0DCEE6FDD376E4F" modified="2018-07-18" version="1">MRQMIGYLQVMRLMLFTSNLFSTLFELTWYKTMLESWLAPLITPDAKILEVGCAGGDLSRWLADKQMQVWAVDSSAASLGKAMHISGQVHFAQADAHHLPFPDGYFDFVVAASLINVVDAPDAVIGEMHRVCRDGGTVAVLVPDQLFTVAEAEKFLETERLTGFSRAAYSTWNRLARKMHADDVYRYFNECGLVNISSNRLLDGLVFAMYGNKLININS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2B0</accession>
    <name>A0A2S9H2B0_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Sec-independent protein translocase protein TatC</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">tatC</name>
        <name evidence="6" type="ORF">S2091_1169</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the TatC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC93996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93996">
        <property type="protein sequence ID" value="PRC93996"/>
        <property type="gene ID" value="S2091_1169"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033281">
        <property type="term" value="C:TAT protein transport complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008320">
        <property type="term" value="F:protein transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043953">
        <property type="term" value="P:protein transport by the Tat complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00902">
        <property type="entry name" value="TatC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002033">
        <property type="entry name" value="TatC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30371">
        <property type="entry name" value="PTHR30371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00902">
        <property type="entry name" value="TatC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01840">
        <property type="entry name" value="TATCFAMILY"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00945">
        <property type="entry name" value="tatC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0811">Translocation</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="24"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="80"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="111"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="158"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="195"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="220"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC93996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="252" mass="27553" checksum="F2A51BCA1804984E" modified="2018-07-18" version="1">MSEQSSNANINSFISHLIELRDRLVRISVVVIIVFLGLMPFAAQIFDLLAAPMMHALPAGAHMIATGVITPFLIPVKITLVLALLISLPWVLYQIWAFVAPGLYAHEKKLVAPLVIASSALFIAGVAFCYFFVFRVVFSFVNQFAPKSISVAPDIESYLDFVLTMFLAFGVTFEVPIIVIVLVRMGFVTVEKLKAIRPYVIVGAFVVAAIVTPPDVTSQLLLAVPMCLLYEIGLLVAPWFKKATAAPVENNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2E1</accession>
    <name>A0A2S9H2E1_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">DNA-directed RNA polymerase subunit beta'</fullName>
            <shortName evidence="8">RNAP subunit beta'</shortName>
            <ecNumber evidence="8">2.7.7.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">RNA polymerase subunit beta'</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Transcriptase subunit beta'</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">rpoC</name>
        <name evidence="11" type="ORF">S2091_1328</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8 9">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7 8 9">
            <text>a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="8">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="8">Binds 2 Zn(2+) ions per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8 9">Belongs to the RNA polymerase beta' chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="8"/>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94155">
        <property type="protein sequence ID" value="PRC94155"/>
        <property type="gene ID" value="S2091_1328"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed 5'-3' RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.274.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.860.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01322">
        <property type="entry name" value="RNApol_bact_RpoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045867">
        <property type="entry name" value="DNA-dir_RpoC_beta_prime"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012754">
        <property type="entry name" value="DNA-dir_RpoC_beta_prime_bact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000722">
        <property type="entry name" value="RNA_pol_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006592">
        <property type="entry name" value="RNA_pol_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007080">
        <property type="entry name" value="RNA_pol_Rpb1_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007066">
        <property type="entry name" value="RNA_pol_Rpb1_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042102">
        <property type="entry name" value="RNA_pol_Rpb1_3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007083">
        <property type="entry name" value="RNA_pol_Rpb1_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007081">
        <property type="entry name" value="RNA_pol_Rpb1_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044893">
        <property type="entry name" value="RNA_pol_Rpb1_clamp_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038120">
        <property type="entry name" value="Rpb1_funnel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19376">
        <property type="entry name" value="PTHR19376"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04997">
        <property type="entry name" value="RNA_pol_Rpb1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00623">
        <property type="entry name" value="RNA_pol_Rpb1_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04983">
        <property type="entry name" value="RNA_pol_Rpb1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05000">
        <property type="entry name" value="RNA_pol_Rpb1_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04998">
        <property type="entry name" value="RNA_pol_Rpb1_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00663">
        <property type="entry name" value="RPOLA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02386">
        <property type="entry name" value="rpoC_TIGR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 8 9" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 8 9" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8 9" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 8 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="RPOLA_N" evidence="10">
        <location>
            <begin position="235"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="70"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="72"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="85"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="88"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="460"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="462"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="464"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="815"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="889"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="896"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="899"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC94155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="1408" mass="155877" checksum="CEB4B5BA9F23FE37" modified="2018-07-18" version="1">MKALLDLFKQVQQNEQFDAIKIGLASPEKIRSWSYGEVKKPETINYRTFKPERDGLFCAKIFGPIKDYECLCGKYKRLKHRGVICEKCGVEVTLTKVRRERMGHIELASPTAHIWFLKSLPSRLGMVLDMTLRDIERVLYFEAYVVTDPGMTPLKKCQIMSEDDYAAKYEEHGDEFTAFMGAEGIRELLRSIDIDRDAETLRVELKESKSEAKIKKYAKRLKVLEAFQRSGIKPDWMIMEVLPVLPPELRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLMELRAPEIITRNEKRMLQEAVDSLLDNGRRGKAMTGANKRPLKSLAEMIKGKGGRFRQNLLGKRVDYSGRSVIVVGPQLKLHQCGLPKLMALELFKPFIFNKLELMGLATTIKAAKKLVEIQEPVVWDILEDVIKEHPVMLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAFNADFDGDQMAVHVPLSVEAQMEARTLMLASNNILFPSNGEPSIVPSQDIVLGLYYATREKINGKNEGMMFPDVSEVIRAYDNKEVELTTRITVRITEYPKNLETGEFEKTITRYETTIGRAILSEILPKGLPFSVLNRALKKKEISKLINISFRKCGLRATVVFADKLMQSGFRLATRAGISICIDDMLVPPQKVTLIAAAEKEVKQIEQQYASGLVTAGERYNKVVDIWGKTGDDVGKAMMERLKVEDVVKRDGTTGTQESFNAIYMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVLQYFISTHGARKGLADTALKTANSGYLTRRLVDVTQDLVVIDDDCGTANGAAMKALVEGGEVIEPLRELILGRVTALDVVNPDTQETLYPAGTLLSEDEVEEIERLGIDEVKVRTPLTCDTRYGLCAMCYGRDLGRGSMVNAGEAVGVIAAQSIGEPGTQLTMRTFHIGGAASRAAVASSIEAKSNGTIRFTATMRYVTNGKGDLIVISRSGEVMITDDHGRERERHKVPYGATLAVTDGMVIKAGVILATWDPLTRPIITEYTGQVKFENVEEGVTVAKQVDEVTGLSTLVAIDAKRRGMATKLLRPQVKLLNEQGQEVKIAGTEHAVTISFQPGALLMVKDGQQVHVGEVLARIPTESQKTRDITGGLPRVAELFEARSPKDAGVLAEVTGTVAFGKETKGKQRLEITDLDGEKHEFLIAKEKQVLVHDGQVVNKGEMIVDGPRDPQDILRLLGIEALARYIVEEVQDVYRLQGVKINDKHIEVIVRQMLRRVTVVNPGDANYIVGEQVERSELLDENDRVVAAGNIPATYENILLGITKASLSTDSFISAASFQETTRVLTEAAIMGKQDSLRGLKENVIVGRLIPAGTGLAYHRARKLKETWEADERTAMLQAEKAAFATHAEASTSDITEGDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2E3</accession>
    <name>A0A2S9H2E3_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">50S ribosomal protein L5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rplE</name>
        <name evidence="9" type="ORF">S2091_1303</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the universal ribosomal protein uL5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94130">
        <property type="protein sequence ID" value="PRC94130"/>
        <property type="gene ID" value="S2091_1303"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01333_B">
        <property type="entry name" value="Ribosomal_L5_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002132">
        <property type="entry name" value="Ribosomal_L5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020930">
        <property type="entry name" value="Ribosomal_L5_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031309">
        <property type="entry name" value="Ribosomal_L5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020929">
        <property type="entry name" value="Ribosomal_L5_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022803">
        <property type="entry name" value="Ribosomal_L5_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031310">
        <property type="entry name" value="Ribosomal_L5_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11994">
        <property type="entry name" value="PTHR11994"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00281">
        <property type="entry name" value="Ribosomal_L5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00673">
        <property type="entry name" value="Ribosomal_L5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002161">
        <property type="entry name" value="Ribosomal_L5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55282">
        <property type="entry name" value="SSF55282"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00358">
        <property type="entry name" value="RIBOSOMAL_L5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="5" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_L5" evidence="7">
        <location>
            <begin position="25"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="domain" description="Ribosomal_L5_C" evidence="8">
        <location>
            <begin position="84"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00029522"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC94130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="179" mass="20041" checksum="67230EA15B8A93F3" modified="2018-07-18" version="1">MARLQEIYKAKVVAALTEKFSYKTVMEVPRITKITLNMGLSEAIADKKIIEHAVGDLTKIAGQKPVVTKARKAIAGFKIREGYPIGCMVTLRGAHMYEFLDRLITVALPRVRDFRGVSGRAFDGRGNYNIGVKEQIIFPEIEYDKIDVLRGMNISITTTAKTDEEAKALLAAFKFPFRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2F7</accession>
    <name>A0A2S9H2F7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Helix-turn-helix domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1219</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94046">
        <property type="protein sequence ID" value="PRC94046"/>
        <property type="gene ID" value="S2091_1219"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="59"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="113" mass="12549" checksum="7CF598E224DB2B04" modified="2018-07-18" version="1">MKTHTEHVQILRDASGHPAYAVIPFADYQALKLGKPKSEATIPNHVVNLAMDKNISAARAWREYLELTQAEIAQRMGVTQSAYAQLEAKKTSRKSTREKIAAALGIEAEQLDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2J8</accession>
    <name>A0A2S9H2J8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0825</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94204">
        <property type="protein sequence ID" value="PRC94204"/>
        <property type="gene ID" value="S2091_0825"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="45" mass="5181" checksum="991115AF505FDF93" modified="2018-07-18" version="1">MWLRQKDVKQNDEDVFIQQSPVAPLPKIFSIDIALHQAKLLTDCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2P5</accession>
    <name>A0A2S9H2P5_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 8">30S ribosomal protein S3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">rpsC</name>
        <name evidence="13" type="ORF">S2091_1309</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7 8">Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 8 10">Belongs to the universal ribosomal protein uS3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94136">
        <property type="protein sequence ID" value="PRC94136"/>
        <property type="gene ID" value="S2091_1309"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1140.32">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01309_B">
        <property type="entry name" value="Ribosomal_S3_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004044">
        <property type="entry name" value="KH_dom_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009019">
        <property type="entry name" value="KH_sf_prok-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005704">
        <property type="entry name" value="Ribosomal_S3_bac-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001351">
        <property type="entry name" value="Ribosomal_S3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036419">
        <property type="entry name" value="Ribosomal_S3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018280">
        <property type="entry name" value="Ribosomal_S3_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07650">
        <property type="entry name" value="KH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00189">
        <property type="entry name" value="Ribosomal_S3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54814">
        <property type="entry name" value="SSF54814"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54821">
        <property type="entry name" value="SSF54821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01009">
        <property type="entry name" value="rpsC_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50823">
        <property type="entry name" value="KH_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00548">
        <property type="entry name" value="RIBOSOMAL_S3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8 10" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 8 10" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4 8 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 8" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="KH type-2" evidence="12">
        <location>
            <begin position="39"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="211"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="217"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01309"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PRC94136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="275" mass="30513" checksum="8557DA71E7A4CCC7" modified="2018-07-18" version="1">MGQKIHPTGFRLAVTRNWSSRWYAGNTNFATMLGEDLKVRAYLKKKLKNASVGRITIERPAKNARITIYSSRPGVVIGKKGEDIEVLKTELSKLMGVPVHVNIEEIRKPEIDAQLIADSIAQQLEKRIMFRRAMKRAMQNAMRLGAQGIKIMSGGRLNGIEIARKEWYREGRVPLHTLRADIDYGTSEAQTTYGIIGVKVWVYKGDRLPNGDAPVIESTPEDDKKRRGPRRDDGKPNSRPRPKQTTTGAPAPAAKRVRAAAPVVAAKAPAEKAGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2Q3</accession>
    <name>A0A2S9H2Q3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0861</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94240">
        <property type="protein sequence ID" value="PRC94240"/>
        <property type="gene ID" value="S2091_0861"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2310.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035093">
        <property type="entry name" value="RelE/ParE_toxin_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143011">
        <property type="entry name" value="SSF143011"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="91" mass="10636" checksum="B865E286F97CA981" modified="2018-07-18" version="1">MSYTLRFTAAYERRAKKFLKQHPELARQYLKTLELLEANPHHPSLRLHPLQGRLTGLHSVSINLSYRITLELLITETMIIPVDVGDHDRVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2W4</accession>
    <name>A0A2S9H2W4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">HipA-like C-terminal domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0946</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94325">
        <property type="protein sequence ID" value="PRC94325"/>
        <property type="gene ID" value="S2091_0946"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012893">
        <property type="entry name" value="HipA-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07804">
        <property type="entry name" value="HipA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HipA_C" evidence="2">
        <location>
            <begin position="171"/>
            <end position="409"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="447" mass="50007" checksum="9C8A83BEF6839DD8" modified="2018-07-18" version="1">MPNQKKLFVFAKIENEFAPAGILTLTEENTNVIASEFAYGTKYLERPNAIEIDPVSLSISPKKAIYKKKVAPVSDLRMFGGIRDAAPDAWGRRVIEAKLKAKANDLPESTYLLEAGSNRVGALDIRPDISSPAKDGVQSVADLHYLLDAAERIEEGAPIPAKLEIIFQAGASLGGARPKATVRDEQGVMWLAKFQSRHERLDVPNIEAATMHLASECGMTVPEVKVIQIGDRNVMLIRRFDRYWANVGEAPPMEDALFRTTPGNGRVEKSLHFISGLTLLSCDEMQSREKSYSDLAHAIRKYCGQTVIRDNNRELFTRMVYNIFVSNDDDHPRNHGFLWDPTLAAWRLSPLYDVMPRSTIATERYQFLGVGQLGRVATLDNAITAKEAFNLSAQEATTIIADVWERVREWKSYFEKFGAPTESIEQATNAFRHIDKISTPKLRALLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H326</accession>
    <name>A0A2S9H326_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1006</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94385">
        <property type="protein sequence ID" value="PRC94385"/>
        <property type="gene ID" value="S2091_1006"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="60"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="101"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="128"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="175" mass="17953" checksum="45518A10E51636C4" modified="2018-07-18" version="1">MNAVLTHTPLWVWAILALLIQRGLVAAQPNSVTLPRLFLLPLIFTVLGAMGLARTGSLLPAALVAAAAGLVLGAAAGWGLFAGQSGYVWDQQSGQLQRPGSWLMLVCSLVAFVLKFGLATVAGWQPELLAGTGGALLTGLVPGIASGLLWGASATQLLLGRTRLSTDGSGGLTWN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H364</accession>
    <name>A0A2S9H364_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Twitching motility protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1045</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GSP E family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94424">
        <property type="protein sequence ID" value="PRC94424"/>
        <property type="gene ID" value="S2091_1045"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01131">
        <property type="entry name" value="PilT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006321">
        <property type="entry name" value="PilT/PilU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001482">
        <property type="entry name" value="T2SS/T4SS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00437">
        <property type="entry name" value="T2SSE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01420">
        <property type="entry name" value="pilT_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00662">
        <property type="entry name" value="T2SP_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="T2SP_E" evidence="2">
        <location>
            <begin position="193"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS00662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="347" mass="38144" checksum="BDBA715EEED933FD" modified="2018-07-18" version="1">MDISELLAFSVKNNASDLHLSAGLPPMIRVHGDVRRINLPPLEHKDVHALIYDIMNDGQRKQFEEFLECDFSFAIPGLARFRVNAFNQERGPAAVLRTIPSKVLSLEQLNTPKIFADLALKPRGLVLVTGPTGSGKSTTLAAMVNHVNENEYGHILTVEDPIEFVHDSKKCLINQREVGPHTMSFNNALRSALREDPDVILVGELRDLETIRLALTAAETGHLVFGTLHTSSAAKTIDRIVDVFPAEEKEMVRSMLSESLQAVISQTLLKTKDGSGRVAAHEIMIGTPAIRNLIRESKIAQMYSAIQTGSNVGMQTLDQNLTELVKRNQISLGAARFAAKIPDNFPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3C6</accession>
    <name>A0A2S9H3C6_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 8">Methionyl-tRNA formyltransferase</fullName>
            <ecNumber evidence="4 8">2.1.2.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">fmt</name>
        <name evidence="11" type="ORF">S2091_1099</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 8">Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>(6S)-10-formyltetrahydrofolate + L-methionyl-tRNA(fMet) = (6S)-5,6,7,8-tetrahydrofolate + H(+) + N-formyl-L-methionyl-tRNA(fMet)</text>
            <dbReference type="Rhea" id="RHEA:24380"/>
            <dbReference type="Rhea" id="RHEA-COMP:9952"/>
            <dbReference type="Rhea" id="RHEA-COMP:9953"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="ChEBI" id="CHEBI:57454"/>
            <dbReference type="ChEBI" id="CHEBI:78530"/>
            <dbReference type="ChEBI" id="CHEBI:78844"/>
            <dbReference type="EC" id="2.1.2.9"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the Fmt family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.9" evidence="4 8"/>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94478">
        <property type="protein sequence ID" value="PRC94478"/>
        <property type="gene ID" value="S2091_1099"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004479">
        <property type="term" value="F:methionyl-tRNA formyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd08646">
        <property type="entry name" value="FMT_core_Met-tRNA-FMT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd08704">
        <property type="entry name" value="Met_tRNA_FMT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00182">
        <property type="entry name" value="Formyl_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005794">
        <property type="entry name" value="Fmt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005793">
        <property type="entry name" value="Formyl_trans_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002376">
        <property type="entry name" value="Formyl_transf_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036477">
        <property type="entry name" value="Formyl_transf_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011034">
        <property type="entry name" value="Formyl_transferase-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044135">
        <property type="entry name" value="Met-tRNA-FMT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041711">
        <property type="entry name" value="Met-tRNA-FMT_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02911">
        <property type="entry name" value="Formyl_trans_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00551">
        <property type="entry name" value="Formyl_trans_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50486">
        <property type="entry name" value="SSF50486"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53328">
        <property type="entry name" value="SSF53328"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00460">
        <property type="entry name" value="fmt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Formyl_trans_N" evidence="9">
        <location>
            <begin position="1"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="domain" description="Formyl_trans_C" evidence="10">
        <location>
            <begin position="211"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="region of interest" description="Tetrahydrofolate (THF) binding" evidence="8">
        <location>
            <begin position="117"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00016014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC94478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="316" mass="33723" checksum="BCDF3E830256C89E" modified="2018-07-18" version="1">MKVVFAGTPEFAATALAAIQAAGHEVVLVLTQPDRPAGRGMQLHASAVKQFALQHQIPVLQPMSLKLDGKYPEQAHDAHELLKATPHDVMIVAAYGLILPESILTIPLYGCLNIHASLLPRWRGAAPIHRAIEAGDAETGITIMQMDQGLDTGAMLSMQRIPIAAADTTTALHDKLAELGGQMIVSVLQQLPTGGLTAIAQPEQGITYAAKIAKEEAALDFALPATVLERKIRAFNPFPGACGVVNGVTLKLWCAELAERPDSAKVGQLILQDHMLLVACGEGALRLFELQKPGGKRLPTAEFLKGFALDDKSCFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3F7</accession>
    <name>A0A2S9H3F7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="10">TonB-Xanth-Caul: TonB-dependent receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">S2091_0503</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94500">
        <property type="protein sequence ID" value="PRC94500"/>
        <property type="gene ID" value="S2091_0503"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010104">
        <property type="entry name" value="TonB_rcpt_bac"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01782">
        <property type="entry name" value="TonB-Xanth-Caul"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="3 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 10" id="KW-0675">Receptor</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="2 6" id="KW-0798">TonB box</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015525457" evidence="7">
        <location>
            <begin position="24"/>
            <end position="890"/>
        </location>
    </feature>
    <feature type="domain" description="Plug" evidence="9">
        <location>
            <begin position="58"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="8">
        <location>
            <begin position="551"/>
            <end position="889"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC94500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="890" mass="94797" checksum="32ED0131E79EDA0C" modified="2018-07-18" version="1">MKKNLTPIASAVAMLMLSVSAQAQQADTSQTAAPTAPAVEQVIVTGVRASLQQSLTQKRDSESIVEVITAEDIGKMPDKNVADSLSRVAGVTTTSAGAAEGSFGENEHVQLRGLAAQYTLTTLNGHSVSSGDWYSVNMAEGSRSVSYTLLPSDIVGEIVVHKSSQADLIEGGMAGTVDIDTRKPLSYPDKLTVVANGEADYGSAAKKVDPNLSALMNWKNDDNTFGITAQVFYQKRDLMRAGSEGVWWNAAPANQAIPALNGTQVSYLSGAVLFQQTRTREGGYLEAEWKPRNDMAFGLSFFDSSLEAANYNTNYMADTINTFSGTKANGNTPVAPSSYTLNGNTVTAANFAPNAFGGNNTGAYSVIEDVAIRPDAKTYSRFLNVDGKWVVDKDLTLTSKLGRTEGGGKTTDVGFEVGSGYVGVGYSQASNGIFQLNVPNGGTFVPNGYGIGGWGDYNVSADSENYGQVDGKWKLNSEMVPSLQFGLRATQHERSQNVTDVSTAAAGTASDSIIPASAIGNYPSGYYGNLPTNPTPGYLPFKISNSYVESWLGQYGTFNKPSAQSSFNIKESTEAGYFMANLAPTDKITGNVGIRIVGTSEDIFAYLPGGAPEYKDSFTDVLPSLNLRFDLAPSLVGRVALNRGMSRPDFGQLAGISISDLQQTGVGSNPNLAPVRSNNLDGTLEWYFAPKSVLALNVFASDLQGVISYGKSTVNYTDQSAGGVIKPYVMSTPANVDGKLSGVDLAYQQGFALGFGVLANYTYTDGRQTTQMATGTCNGTATQDCSLYGTSKNAYNVGVYFENDKFSTNLSYTYRNTYKLANSGGVDYFQSGNGSLNLSANYTYSKNLTFTFSGQNLTDPLLTTYQTNTTEIHGVYKNGMMLYAGARVKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3I9</accession>
    <name>A0A2S9H3I9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_0552</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94549">
        <property type="protein sequence ID" value="PRC94549"/>
        <property type="gene ID" value="S2091_0552"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="4"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="155"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC94549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="224" mass="24454" checksum="738D58676ABC0380" modified="2018-07-18" version="1">MATKVAIIEDNVEFLNRFRQVIQSDSDFAFVGSASNGADGIALIDSIRADAYLVDLGLPDINGIELIKHAVKTYPECDVMVITMFADDAHVIKSIEAGATGYILKDSSSLDILDCIRTLRDGGSPISPMIARRILQRFQPVTINPAPVAENAPPIIPSSELLSEREYQVLHALSKGLSFKEIAAKYYISTHTVARHVKKIYRVLAVHSRGEAVYEATKLGILSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3J0</accession>
    <name>A0A2S9H3J0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="8">NagA: N-acetylglucosamine-6-phosphate deacetylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_0506</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
        <text evidence="6">Binds 1 divalent metal cation per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the metallo-dependent hydrolases superfamily. NagA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94503">
        <property type="protein sequence ID" value="PRC94503"/>
        <property type="gene ID" value="S2091_0506"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008448">
        <property type="term" value="F:N-acetylglucosamine-6-phosphate deacetylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006044">
        <property type="term" value="P:N-acetylglucosamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00854">
        <property type="entry name" value="NagA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003764">
        <property type="entry name" value="GlcNAc_6-P_deAcase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11113:SF14">
        <property type="entry name" value="PTHR11113:SF14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038994">
        <property type="entry name" value="NagA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="SSF51338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00221">
        <property type="entry name" value="nagA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydro-rel" evidence="7">
        <location>
            <begin position="49"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="215"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="300"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="4">
        <location>
            <position position="267"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="128"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="139"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="191"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="212"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="223"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="246"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR038994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR038994-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR038994-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR038994-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC94503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="376" mass="40004" checksum="07413A0B01AFA251" modified="2018-07-18" version="1">MSGLEQSNAQLHGNILTPQGWVSGSIDFNQRIIAIQGNAVDPAQNDQPYILPGFIDLHVHGAGGKDMMEAGDAAQVIARMHAQHGTTCMLATTMTAPMSDLETALQGINHALKNHGNGMARILGVHLEGPYINPNKLGAQPNYAQTATLTDVQNLNAIAPIKLITVAPEMDGHLALISELTKMGMKVQLGHTLGTYEEGVAALENGAAGFTHLFNAMSRLDHRAPGMVGAALAHANYSEIIPDLLHVHPGAIKAAMRAIPHLYCVTDSTAASGMPDGQYMLGRQQVHKCMGGVRLADGTLAGSTLTMDQALRNLVSIGLELADASKRVSTFAADYMGLTERGRLQQQSYADLVVLDRELNLIAVFVEGEKIDLINA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3U9</accession>
    <name>A0A2S9H3U9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ABC-type sugar transport system periplasmic component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0651</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94648">
        <property type="protein sequence ID" value="PRC94648"/>
        <property type="gene ID" value="S2091_0651"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008643">
        <property type="term" value="P:carbohydrate transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025997">
        <property type="entry name" value="SBP_2_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13407">
        <property type="entry name" value="Peripla_BP_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015398673" evidence="1">
        <location>
            <begin position="29"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="domain" description="Peripla_BP_4" evidence="2">
        <location>
            <begin position="34"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="324" mass="34529" checksum="9655E25125EACC69" modified="2018-07-18" version="1">MTIGSFLKNVCLASTVLLALSLSNSAIAANKQIVYISAKSDLPFWKTIGKGVKSIADANGYSYLELDSNLNSQTQLKNAQEAIAKNVAGIVISPIDSKTAPEVLALAMKAKIPVVIADVGTNGGEYASYIKSDNYRGAYDVGVVLATKMKDKGWSESPFAMITISLARKNGQDRSNGFRDALKDAGITKETGLRQMQTYSAEETFKFTKEILETTPGLRGLFIETDQPVTGAMQAIKAAKRTGEILIVSFDAMPEVAELLKSDALIAVGMQQPYLMGSKAAEALFSSMQGVAPAKQILIPILVGTGKNITQLMPTVSKTVFGGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3W8</accession>
    <name>A0A2S9H3W8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0671</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94668">
        <property type="protein sequence ID" value="PRC94668"/>
        <property type="gene ID" value="S2091_0671"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="120" mass="13345" checksum="FE7454557713F5E2" modified="2018-07-18" version="1">MSKKKIEGTVEAWESGELGSSIEHARVAPPEIAKAVDEAMGMQAISIRLQNDLIEEFKLIAGRYGIGYQPLMRKALTEFARTELRKLAFEHSKEIERLSKQATVELEVLSAAVSKHKAHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3X8</accession>
    <name>A0A2S9H3X8_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF2807 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0681</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94678">
        <property type="protein sequence ID" value="PRC94678"/>
        <property type="gene ID" value="S2091_0681"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021255">
        <property type="entry name" value="DUF2807"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10988">
        <property type="entry name" value="DUF2807"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015461031" description="DUF2807 domain-containing protein" evidence="1">
        <location>
            <begin position="22"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="domain" description="DUF2807" evidence="2">
        <location>
            <begin position="31"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="273" mass="28632" checksum="E21B86A56FA38496" modified="2018-07-18" version="1">MKKITHIIIWALAFISSAALAQTKEVRNVDKFTKITSTVSGNIYLKQGSPQKVELEGKADILADIETEVSRGKLTIRKKGSGYSWGWHKENPLNVYITVENIEALNMSGSGNLVGQTKFTGNNVDLTVSGSGALQAEMELTGAVDVDLSGSGDINLKGKFQNLKNEVSGSGDVVLSVIVANQVDFDISGSGKIKASGTAQNVKASISGSGNLYATNLVTDKYRVHISGSGDAAIDVNGDLDAGTSGSGDVTYRGNPSHVITHNSGSGSVRKIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H406</accession>
    <name>A0A2S9H406_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0715</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94712">
        <property type="protein sequence ID" value="PRC94712"/>
        <property type="gene ID" value="S2091_0715"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002818">
        <property type="entry name" value="DJ-1/PfpI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018062">
        <property type="entry name" value="HTH_AraC-typ_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01965">
        <property type="entry name" value="DJ-1_PfpI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00041">
        <property type="entry name" value="HTH_ARAC_FAMILY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="2">
        <location>
            <begin position="242"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="342" mass="37123" checksum="37448FF151500976" modified="2018-07-18" version="1">MIKKKPTADLDYRNTKIANHINSIHVWIVVFPGFLLLDATGPVQAFSTCNDEYSDSGGSPPYVIHMVSQHGGEIKSSSGVGVSTTPLPAIKLLSGATLVVSGGHRIELAVAEDDLVCWIGKASGIVKRCASVCNGAFLLAKAGVLTNKKACTHWKDTDSLRIQYPDIHVLDDAIYIKDGSIYSSAGVTSGIDLCLSLIEEDLGRKAALSVAKSLVVFQKRPGGQRQFSTALLSESSSSSLADQLINWLRPRIHEQIDVDRMSDAISLSSRSLHRRLQQEAGLSPAQLLSRVRMEVACKLLESGSHSIKKIAEKSGFGTEYNLRRSFAKNLGVLPTEYRERFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H489</accession>
    <name>A0A2S9H489_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Biopolymer transport protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_0689</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the ExbD/TolR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94686">
        <property type="protein sequence ID" value="PRC94686"/>
        <property type="gene ID" value="S2091_0689"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003400">
        <property type="entry name" value="ExbD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30558">
        <property type="entry name" value="PTHR30558"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02472">
        <property type="entry name" value="ExbD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC94686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="135" mass="14904" checksum="2146EF0238BF041B" modified="2018-07-18" version="1">MRSWDEQKKRKARVEIIPMIDVMMFLLVFFVLISLNVIPALGLKTHLPGASSSQNLTPQNKAVITLGLNNALQVDGVNTSMSEIVARLNQAKKGSEKLNVIINSDSGVEVQRLVDVMDNLKKNGFESISIATRKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4B4</accession>
    <name>A0A2S9H4B4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Arsenate reductase and related proteins glutaredoxin family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0766</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the ArsC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94763">
        <property type="protein sequence ID" value="PRC94763"/>
        <property type="gene ID" value="S2091_0766"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006660">
        <property type="entry name" value="Arsenate_reductase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30041">
        <property type="entry name" value="PTHR30041"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03960">
        <property type="entry name" value="ArsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51353">
        <property type="entry name" value="ARSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="108" mass="12292" checksum="2DCF16494413418C" modified="2018-07-18" version="1">MITIYHNPRCSKSRAALELTQQFAEQNQLALSVIEYLKTLLNLDELRALQKQLGEQSRDMVREYGALEPEQQCAILLAQPELLQRPIISYQGRAVIGRSPESIQALLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4C3</accession>
    <name>A0A2S9H4C3_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PlsC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0776</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94773">
        <property type="protein sequence ID" value="PRC94773"/>
        <property type="gene ID" value="S2091_0776"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002123">
        <property type="entry name" value="Plipid/glycerol_acylTrfase"/>
    </dbReference>
    <dbReference type="SMART" id="SM00563">
        <property type="entry name" value="PlsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PlsC" evidence="1">
        <location>
            <begin position="41"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="202" mass="23045" checksum="89B4A673E0062BB0" modified="2018-07-18" version="1">MQTPIFTSQHAPNIFSKISLAALNALGWTLRYDGLPATRGVMIFYPHTSNWDFFYGMLTKWAIAFPLRFLVKEKLFKGVSGFFIGSFVRYWGGEPIERGVSSGAIPHLAQRMQQADWFWLAITPEGTRSYTPYWRSGFYHIALTAKVPLVCAFIDYRRKEIGICQAIELTGDEAVDLAQIQIAYQEMQGKHPQQQGAIEFKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4G3</accession>
    <name>A0A2S9H4G3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acetyltransferase (GNAT) domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0067</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94872">
        <property type="protein sequence ID" value="PRC94872"/>
        <property type="gene ID" value="S2091_0067"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="6"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="150" mass="16858" checksum="D2D605B454CB475D" modified="2018-07-18" version="1">MPTNTLTFRRATPDDISSMSHIRLAVKENILSNPRIITPQMYLDYLDKLGRGWVCENAGHIVGFSYAAHEDSSIWALFVLPEQEGLGIGKQLLNLATDYLFGLGNDQIKLGTTPNTRADRFYAASGWERGEMKNAKEVAYVLHKPENYPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4K9</accession>
    <name>A0A2S9H4K9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">LytTr DNA-binding domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0066</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94871">
        <property type="protein sequence ID" value="PRC94871"/>
        <property type="gene ID" value="S2091_0066"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007492">
        <property type="entry name" value="LytTR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012379">
        <property type="entry name" value="LytTR_MHYE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04397">
        <property type="entry name" value="LytTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF031767">
        <property type="entry name" value="MHYE_LytTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00850">
        <property type="entry name" value="LytTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50930">
        <property type="entry name" value="HTH_LYTTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="95"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="141"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="domain" description="HTH LytTR-type" evidence="2">
        <location>
            <begin position="186"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="290" mass="34306" checksum="028E8779A18574E6" modified="2018-07-18" version="1">MSSHQTDLLTRYQKVRRYVEPGIWIIFWCVQALTLSRISWLDQLRQGKDLEWWKPAVWESSSCLVLLLLIPAVLSFERKLPLRWGLMRRNLRWHFIASLAFCLVHVSAMVAIRKLAYFSQHQTYDFGNWQHELAYEYLKDFQTYFAIIIGVSFYRLILLRWQGEASLLQEPDTGPSVEPLERPERFLVRSLGKEFLLPAAEIEWIQAWGNYVNLRVRGHDYPLRSTMAAIEQRIDPKRFVRVHRSYIANLNFITEIEPLDSGDARAKLRDGQQIPVSRRYRDELRKLAAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4N9</accession>
    <name>A0A2S9H4N9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Dyp-type peroxidase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_0123</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94928">
        <property type="protein sequence ID" value="PRC94928"/>
        <property type="gene ID" value="S2091_0123"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006314">
        <property type="entry name" value="Dyp_peroxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04261">
        <property type="entry name" value="Dyp_perox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01413">
        <property type="entry name" value="Dyp_perox_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51404">
        <property type="entry name" value="DYP_PEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2 4" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015777256" evidence="3">
        <location>
            <begin position="36"/>
            <end position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC94928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="429" mass="47052" checksum="A191BC8B832A9B6B" modified="2018-07-18" version="1">MNNSDDKKHNATRRNFLTRAVVAAAAAPLASQAFAKPVESATSATPASTSTSEPFWGKHQGGIATPIQRNTYFMAFDMLTTERTELIALLKAWTEAAAEMASAPAKIDAHPDLAQAPADSGATIGLPNSRLTITFGFGPTLFEKDGVDRFGIAKNRPAALADLPRFNGDQLIPERTGGDISIQASADDAQVVEYALRRMVSLAYGIAKIRWAQNGFTAGFKAGETPRNQMGFKDGTINVPTKDPAQMHQFVWAGDEGPEWMRDGSYMVIRPIRIALEHWDRMKLGFQEETVGRHKYSGAPIGKQHEFDKLDLDATDKDGNLLIAENSHARLAAPESNDGAQILRRAFNYDNGVAQIAERWPPWHQAVTFDAGLLFQCYQRDPRTGFTKMFEKMAKFDMLNQFTTHIGSGLFACPPGAKPGEFIGQKLFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4S7</accession>
    <name>A0A2S9H4S7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0179</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94984">
        <property type="protein sequence ID" value="PRC94984"/>
        <property type="gene ID" value="S2091_0179"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08413">
        <property type="entry name" value="PBP2_CysB_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037423">
        <property type="entry name" value="CysB_PBP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="310" mass="34118" checksum="63DC3AA1A26E865B" modified="2018-07-18" version="1">MNFQQLRSIREASRCGFNLTEVANALFTSQPGVSRQIREVEEELGVEIFERNGKRLMGLTEPGKGILVIIERLLVEAENLRRASDDYTDHAKGTLTIATTHTQARYVLPRVVQAFRQAFPDVRIALQQSSPEHIADLVLSGKADIGIATEGLSQYKDLASFACYEWSHVLVVPEGHPLLACVANGDYLSLHDLATWPLITYDIGFTGRGHIDEAFHISGAHADIVLTAMDADVIAQYVALGMGVGIVASMAVDSLHAHGLKTIPASHLFSPNVTRLAVRRGTYLRSYAIDFIQQFSPNLQREKIITEVAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4Z5</accession>
    <name>A0A2S9H4Z5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Prepilin-type N-terminal cleavage/methylation domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0249</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95054">
        <property type="protein sequence ID" value="PRC95054"/>
        <property type="gene ID" value="S2091_0249"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043683">
        <property type="term" value="P:type IV pilus assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031982">
        <property type="entry name" value="PilE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16732">
        <property type="entry name" value="ComP_DUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC95054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="177" mass="19995" checksum="4E5188FD616DFD8E" modified="2018-07-18" version="1">MELLQILIATNKSSINVVEDNNIMFTEKHHNFRRGFTLMELIITISIIAIIAALAYPSYQDSVRKTRRAEAKTALYSIMQQQERFYMQRNTYSAFSSTTSNNPFKWWSGERAADSFYELKAEACTGKNLNECVLLTAIPGTENVMSSFTDPVCGNLTLNSANQKSYSISTDANSLCW</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H501</accession>
    <name>A0A2S9H501_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0254</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95059">
        <property type="protein sequence ID" value="PRC95059"/>
        <property type="gene ID" value="S2091_0254"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2310.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035093">
        <property type="entry name" value="RelE/ParE_toxin_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC95059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="86" mass="9600" checksum="313A54B9BA8BDCEB" modified="2018-07-18" version="1">MADNHWAVRLSAAAESDIRQIVLWSRDHFGIDQANIYVNTITLAPKKLNAGPTIIGTKERSDIGTIYGHFILPEINAKAGILFYFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5E2</accession>
    <name>A0A2S9H5E2_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase</fullName>
            <ecNumber evidence="10">2.4.1.227</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">murG</name>
        <name evidence="13" type="ORF">S2091_0399</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>di-trans-octa-cis-undecaprenyl diphospho-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine + UDP-N-acetyl-alpha-D-glucosamine = di-trans-octa-cis-undecaprenyl diphospho-[N-acetyl-alpha-D-glucosaminyl-(1-&gt;4)]-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine + H(+) + UDP</text>
            <dbReference type="Rhea" id="RHEA:31227"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:61387"/>
            <dbReference type="ChEBI" id="CHEBI:61388"/>
            <dbReference type="EC" id="2.4.1.227"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="10">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cell membrane</location>
            <topology evidence="10">Peripheral membrane protein</topology>
            <orientation evidence="10">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the glycosyltransferase 28 family. MurG subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.227" evidence="10"/>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95204">
        <property type="protein sequence ID" value="PRC95204"/>
        <property type="gene ID" value="S2091_0399"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051991">
        <property type="term" value="F:UDP-N-acetyl-D-glucosamine:N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenol 4-beta-N-acetylglucosaminlytransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050511">
        <property type="term" value="F:undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030259">
        <property type="term" value="P:lipid glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00033">
        <property type="entry name" value="MurG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006009">
        <property type="entry name" value="GlcNAc_MurG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007235">
        <property type="entry name" value="Glyco_trans_28_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004276">
        <property type="entry name" value="GlycoTrans_28_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04101">
        <property type="entry name" value="Glyco_tran_28_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03033">
        <property type="entry name" value="Glyco_transf_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01133">
        <property type="entry name" value="murG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2 10" id="KW-0132">Cell division</keyword>
    <keyword evidence="1 10" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 10" id="KW-0133">Cell shape</keyword>
    <keyword evidence="9 10" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="3 10 13" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 10" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_transf_28" evidence="11">
        <location>
            <begin position="10"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_tran_28_C" evidence="12">
        <location>
            <begin position="191"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="region of interest" description="UDP-N-acetyl-alpha-D-glucosamine binding" evidence="10">
        <location>
            <begin position="17"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="169"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="197"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="251"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="296"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF03033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF04101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PRC95204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="369" mass="39178" checksum="C6DE3A0DEFA695D1" modified="2018-07-18" version="1">MNMATKAKRIMIMAAGTGGHIFPGLAIAKTLQERGWEVSWLGTAHGMEGEIVAKNNIAMDVLDFAGMRGKGWRHSLTGAVKLVASFLRCFQFLGQRKPDVVLGMGGYVTVPGGLMAKLRGIPLVLVNADAALLLSNKFLARFSQRVLFGFPADFGVAASIAQVTGNPVRSEICTLPIPTVRFFGRSGPLNILVVGGSLGAKILNETLPAALALLPTELRPNVTHQSGKANIAALQAAYEKAQVQAKVVAFIDDMTSEYASADLVICRAGAITVSELTAAGVASVLVPLMASSTTHQSNNASWMAEQQAALHLPQKEMTAEKLAQLLKTMTRADCQVLAEAAYKIGQRQANNKIADVLEELIGKRSGKQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5J1</accession>
    <name>A0A2S9H5J1_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Superoxide dismutase [Cu-Zn]</fullName>
            <ecNumber evidence="4">1.15.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_0454</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Destroys radicals which are normally produced within the cells and which are toxic to biological systems.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>2 H(+) + 2 superoxide = H2O2 + O2</text>
            <dbReference type="Rhea" id="RHEA:20696"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:18421"/>
            <dbReference type="EC" id="1.15.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Cu cation</name>
            <dbReference type="ChEBI" id="CHEBI:23378"/>
        </cofactor>
        <text evidence="4">Binds 1 copper ion per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="4">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the Cu-Zn superoxide dismutase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.15.1.1" evidence="4"/>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95259">
        <property type="protein sequence ID" value="PRC95259"/>
        <property type="gene ID" value="S2091_0454"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004784">
        <property type="term" value="F:superoxide dismutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00305">
        <property type="entry name" value="Cu-Zn_Superoxide_Dismutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036423">
        <property type="entry name" value="SOD-like_Cu/Zn_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024134">
        <property type="entry name" value="SOD_Cu/Zn_/chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018152">
        <property type="entry name" value="SOD_Cu/Zn_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001424">
        <property type="entry name" value="SOD_Cu_Zn_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10003">
        <property type="entry name" value="PTHR10003"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00080">
        <property type="entry name" value="Sod_Cu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49329">
        <property type="entry name" value="SSF49329"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00332">
        <property type="entry name" value="SOD_CU_ZN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0186">Copper</keyword>
    <keyword evidence="1 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="2 4" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015596785" description="Superoxide dismutase [Cu-Zn]" evidence="5">
        <location>
            <begin position="27"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="domain" description="Sod_Cu" evidence="6">
        <location>
            <begin position="44"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC95259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="178" mass="18443" checksum="58A9DEAE76FF6F50" modified="2018-07-18" version="1">MKSNSRMMFKLSSALLITMVSASALATEIIMNEVDAAGKVTAVGSVMLTETPYGVLFTPNLKNLPAGMHGFHLHEKSNCGNTTTDSVVMVAGAAGGHWDPEHTLKHEGPYGQGHLGDLPSLYVAADGTATIPVLAPRIKDLSQVHGLALMVHAGGDNHSDHPAKLGGGGVRIACGLVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5L1</accession>
    <name>A0A2S9H5L1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Gram-negative porin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_0361</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95166">
        <property type="protein sequence ID" value="PRC95166"/>
        <property type="gene ID" value="S2091_0361"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046930">
        <property type="term" value="C:pore complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015288">
        <property type="term" value="F:porin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006811">
        <property type="term" value="P:ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00342">
        <property type="entry name" value="gram_neg_porins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033900">
        <property type="entry name" value="Gram_neg_porin_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023614">
        <property type="entry name" value="Porin_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13609">
        <property type="entry name" value="Porin_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0406">Ion transport</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0626">Porin</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1134">Transmembrane beta strand</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015511853" evidence="4">
        <location>
            <begin position="32"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="domain" description="Porin_4" evidence="5">
        <location>
            <begin position="18"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF13609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC95166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="411" mass="41796" checksum="33C52CB94E1FA31D" modified="2018-07-18" version="1">MRQSKKTQQSKKYLKWMALASLSAISMTAAAQSSVELFGVLDLGILSESNTSNPALGYLPNPSDKGHLTEMKDGGVTLSYWGIKGGEDLGGGLKANFVLQGNLNAANGTAGGPNSSGSTSLFNQQANVGISGNFGALKAGRVISPIFDAFASTDVRGGTFFGSGLTAVVGLNSATGSFSGASSNASLGALYNDNAIVYSSPVLNGFAASIEVTMGGVAGNSAALRQSAATLTYTSENWKFDGLIYNGNDDGIKAAATPDGTNTNRLVQVGGMYTNGAVSVAAGYFKGSNPSDTGAGMNPALLGGAQTSGNLDMYSVGLGYKVTTALKLTSGYYDLKDQANSGNHAAMFVIGADYALSARTKFYADAASVNNVGSNMNMAPEYGVPVTAGGKGAVSDGITSTAFMLGIRHKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSF9</accession>
    <name>A0A2S9GSF9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">GGDEF: diguanylate cyclase (GGDEF) domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_4609</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000039">
        <property type="protein sequence ID" value="PRC90659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90659">
        <property type="protein sequence ID" value="PRC90659"/>
        <property type="gene ID" value="S2091_4609"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01948">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021800">
        <property type="entry name" value="DUF3369"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001633">
        <property type="entry name" value="EAL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035919">
        <property type="entry name" value="EAL_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11849">
        <property type="entry name" value="DUF3369"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00563">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00052">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141868">
        <property type="entry name" value="SSF141868"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50883">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="34"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="4">
        <location>
            <begin position="352"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="domain" description="EAL" evidence="3">
        <location>
            <begin position="488"/>
            <end position="741"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC90659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="741" mass="83625" checksum="0D473591D9C8F809" modified="2018-07-18" version="1">MSDIQHSSHDELIFLEELEKSDPQVKHEGNLTWRIMIIDDDPDVHSATTFALSSLAIQNRSLSFLHAYSAVQAKEILKNETDIAVILLDVVMEQEDAGLQLVNLIRNEMNLSEVRIILRTGQPGYAPEIDAIRDFDINDYKTKSELTRTKLFTTITSAIRSYDQICSINTLRRASDITTRSSRELISQTNLNEFSAIAIRSIIDYFEMPNINLLLFKQEEPGGAVNIIAANGQFSHLLNTPIKSTDNAIILHTIENCLVQQQNILESNHAALYLSNTTQTRYALYVGVNKNITPQDARFLDVFSSNVSVCLDNVLLNIRLRNHAFTDPLTNMPNRLKLLHMLDQILAQKNRPQTTLALIDIDHFAETNNALGHQFGDLLLCAVAERLRHHFEHSCKLARIGSDTFSIVGHNDIVRPEIILSLFYAPFLIEKQDVQLSATIGLVKLDDYQGDTSDALKDTNIALKRAKKQQRTGYVYFTNNMGVEIRERVRLMRALNSAFQKNHLFVVYQPQVNIGTGKAVGAEALLRWKTTEGKFIPPDQFIPIAEYSGLIIELGDWVLRNACYELQNLIKKGYTDFKMSVNVSQAQFLHPEFLNSVRRAITDTGIPPELLDLEITESMAMEDPIFLMETLHQLKKIGVKISIDDFGTGFSSLSYLQKLPIDQLKIDRSFVSQIVDASSSASIPKMIIQLCQSLGLTVIAEGVEELKQAEALMSFGCSLAQGYYYAKPLETPKLHEWLEHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSI2</accession>
    <name>A0A2S9GSI2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_4621</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000039">
        <property type="protein sequence ID" value="PRC90671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90671">
        <property type="protein sequence ID" value="PRC90671"/>
        <property type="gene ID" value="S2091_4621"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015573190" evidence="2">
        <location>
            <begin position="23"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC90671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="91" mass="10090" checksum="9EBAA5899E7033D2" modified="2018-07-18" version="1">MKTTTYIFFIAFSIATFSSAMAAQDQLLLDQIHKKHDQHMTSSQAIDSAKMAQPLDHEPHAVSTPPVNEQRGLRVQPTDMNTPAKAIEPSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSM0</accession>
    <name>A0A2S9GSM0_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 9">4-hydroxy-tetrahydrodipicolinate synthase</fullName>
            <shortName evidence="9">HTPA synthase</shortName>
            <ecNumber evidence="4 9">4.3.3.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">dapA</name>
        <name evidence="11" type="ORF">S2091_4581</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 9">Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>L-aspartate 4-semialdehyde + pyruvate = (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + H(+) + H2O</text>
            <dbReference type="Rhea" id="RHEA:34171"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:67139"/>
            <dbReference type="ChEBI" id="CHEBI:537519"/>
            <dbReference type="EC" id="4.3.3.7"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 9">Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; (S)-tetrahydrodipicolinate from L-aspartate: step 3/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homotetramer; dimer of dimers.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9 10">Belongs to the DapA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.</text>
    </comment>
    <dbReference type="EC" id="4.3.3.7" evidence="4 9"/>
    <dbReference type="EMBL" id="PUGF01000038">
        <property type="protein sequence ID" value="PRC90688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90688">
        <property type="protein sequence ID" value="PRC90688"/>
        <property type="gene ID" value="S2091_4581"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00034">
        <property type="reaction ID" value="UER00017"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008840">
        <property type="term" value="F:4-hydroxy-tetrahydrodipicolinate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019877">
        <property type="term" value="P:diaminopimelate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00950">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00418">
        <property type="entry name" value="DapA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005263">
        <property type="entry name" value="DapA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002220">
        <property type="entry name" value="DapA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020625">
        <property type="entry name" value="Schiff_base-form_aldolases_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020624">
        <property type="entry name" value="Schiff_base-form_aldolases_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12128">
        <property type="entry name" value="PTHR12128"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00701">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001365">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00146">
        <property type="entry name" value="DHPICSNTHASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01130">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00674">
        <property type="entry name" value="dapA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00665">
        <property type="entry name" value="DHDPS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00666">
        <property type="entry name" value="DHDPS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 9" id="KW-0220">Diaminopimelate biosynthesis</keyword>
    <keyword evidence="9 10" id="KW-0456">Lyase</keyword>
    <keyword evidence="7 9" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 9" id="KW-0704">Schiff base</keyword>
    <feature type="active site" description="Proton donor/acceptor" evidence="9">
        <location>
            <position position="135"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with substrate" evidence="9">
        <location>
            <position position="163"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="47"/>
        </location>
        <ligand>
            <name>pyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="205"/>
        </location>
        <ligand>
            <name>pyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
        </ligand>
    </feature>
    <feature type="site" description="Part of a proton relay during catalysis" evidence="9">
        <location>
            <position position="46"/>
        </location>
    </feature>
    <feature type="site" description="Part of a proton relay during catalysis" evidence="9">
        <location>
            <position position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR001365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC90688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="294" mass="31358" checksum="2CB01E3F6A7243D4" modified="2018-07-18" version="1">MTMITGSLVAIVTPMHADGSLDIPGLRKLIDWHISEGTDGIVIAGTTGESATVSVEEHRELIQVAVEHTNKRIPVIAGSGGNSTQEAIALTAYAKEVGADASLQVVPYYNRPTQEGMYQHFKKIAESVDIPLILYNVPGRTASDMSNETIARLAQIPNIVGIKEASGNIGRDIELLAMVPEGFAIYSGDDLSAMALMLCGGKGNISVTANIAPRAMHELCVAAMAGDIAKAKAINQPLIPLHMKLFIEPNPVPVKWAMAEMGLIPTGIRLPLVTFSSQYHETLANSLRAVDLLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSP9</accession>
    <name>A0A2S9GSP9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NMT1/THI5 like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4570</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000037">
        <property type="protein sequence ID" value="PRC90744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90744">
        <property type="protein sequence ID" value="PRC90744"/>
        <property type="gene ID" value="S2091_4570"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011852">
        <property type="entry name" value="TRAP_TAXI"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42941">
        <property type="entry name" value="PTHR42941"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16868">
        <property type="entry name" value="NMT1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="331"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="446" mass="49873" checksum="0771AC27844EF985" modified="2018-07-18" version="1">MQKFKFRRGRSLFKDIVWTILPILLLGVGGSWIAYHYIDPAPPHRLVILTGAEDSSYQDFAKSYKEILAGDGIELVIRQSNGALDNHQRLRDPNSDVDLGFLQDGLNETASDDEVEPLSLGSISYEPLWVFYRAKQPITRFSGLAGKRLAIGREGSGTKLLATRLLAASGVTADNSTLQAIGRDEAAAQLLAGKLDAVFVIGEPDSPLVQQLAADSQVRILDLDQAAAIARHFPYLHELRVPHGLIDIRRNLPAQDITLLATTTTLAARETVHPALISLLMKAMHETHSEAGLLHSANEFPSAKDVDLELSKEAEHYYKSGPPLLQRYLPFWLATLIDRAALVLIPLLAALIPVIRAIPQIYNWRIRRQIYRWYGELSFLETQLRDKPAEVEIAVAIRQLDHIEEKVQRAKLPLTFAEHSYVLKEHIDFVRRRILKPETKPTGPVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GT30</accession>
    <name>A0A2S9GT30_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phage major capsid protein, P2 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4446</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000034">
        <property type="protein sequence ID" value="PRC90865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90865">
        <property type="protein sequence ID" value="PRC90865"/>
        <property type="gene ID" value="S2091_4446"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006441">
        <property type="entry name" value="Phage_P2_GpN"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05125">
        <property type="entry name" value="Phage_cap_P2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01551">
        <property type="entry name" value="major_capsid_P2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="67"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="79"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="343" mass="38312" checksum="EBA6A2FEC510BEC2" modified="2018-07-18" version="1">MKKPTRLAFNAYTAQLASLNDTGNATDTFSVVPSVQQRLENKIQESSAFLSRVNIIGVTEQEGEKLGLGISSPIASRTDTNKGDRKTRDPSDLDSQRYRCEKTNFDTHIPYAKLDAWAKFPDFQDRVARQIFIRQGLDRMVVGFHGASVSPDTDITKNPLLQDVNKGWLQHYREQAPSRVMGSGSTDGKVTIGAGGDYENLDAAVFDALNLLEPWYRDDTGLVVIMGRQLLTDKYFPMVNVNQAPSETLAADIVMSQKRIGGLPAVTVPYFPGNALFITRYDNLSIYFQEGARRRRVVDEAKRDRIENYESSNDAYVVEDFGLGALIENITLVTKTEPPEDKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GT58</accession>
    <name>A0A2S9GT58_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4393</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the BlaI transcriptional regulatory family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000033">
        <property type="protein sequence ID" value="PRC90900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90900">
        <property type="protein sequence ID" value="PRC90900"/>
        <property type="gene ID" value="S2091_4393"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005650">
        <property type="entry name" value="BlaI_family"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34134">
        <property type="entry name" value="PTHR34134"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03965">
        <property type="entry name" value="Penicillinase_R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF019455">
        <property type="entry name" value="CopR_AtkY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="124" mass="14216" checksum="258E29BB057D7A6F" modified="2018-07-18" version="1">MTITISEAESAVMKIFWDKNPLSCSDVVTALADEQDWQEPTVKTFLNRLLKKGALRSEKDGRRFLYWPVLTREQWLSSESDSMLKRLFGGQLAPFVAHFGAHKKLSKKEVAELKALIDRMSDEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GT62</accession>
    <name>A0A2S9GT62_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 4">Imidazolonepropionase</fullName>
            <ecNumber evidence="1 4">3.5.2.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Imidazolone-5-propionate hydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">hutI</name>
        <name evidence="6" type="ORF">S2091_4388</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>4-imidazolone-5-propanoate + H2O = N-formimidoyl-L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:23660"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:58928"/>
            <dbReference type="ChEBI" id="CHEBI:77893"/>
            <dbReference type="EC" id="3.5.2.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <cofactor evidence="4">
            <name>Fe(3+)</name>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
        </cofactor>
        <text evidence="4">Binds 1 zinc or iron ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Amino-acid degradation; L-histidine degradation into L-glutamate; N-formimidoyl-L-glutamate from L-histidine: step 3/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the metallo-dependent hydrolases superfamily. HutI family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.2.7" evidence="1 4"/>
    <dbReference type="EMBL" id="PUGF01000033">
        <property type="protein sequence ID" value="PRC90895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90895">
        <property type="protein sequence ID" value="PRC90895"/>
        <property type="gene ID" value="S2091_4388"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00379">
        <property type="reaction ID" value="UER00551"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050480">
        <property type="term" value="F:imidazolonepropionase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019556">
        <property type="term" value="P:histidine catabolic process to glutamate and formamide"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019557">
        <property type="term" value="P:histidine catabolic process to glutamate and formate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01296">
        <property type="entry name" value="Imidazolone-5PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00372">
        <property type="entry name" value="HutI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005920">
        <property type="entry name" value="HutI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42752">
        <property type="entry name" value="PTHR42752"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="SSF51338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01224">
        <property type="entry name" value="hutI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4" id="KW-0369">Histidine metabolism</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 4" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Amidohydro-rel" evidence="5">
        <location>
            <begin position="65"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="73"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="75"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="82"/>
        </location>
        <ligand>
            <name>4-imidazolone-5-propanoate</name>
            <dbReference type="ChEBI" id="CHEBI:77893"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="145"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="178"/>
        </location>
        <ligand>
            <name>4-imidazolone-5-propanoate</name>
            <dbReference type="ChEBI" id="CHEBI:77893"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="243"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="246"/>
        </location>
        <ligand>
            <name>4-imidazolone-5-propanoate</name>
            <dbReference type="ChEBI" id="CHEBI:77893"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="318"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="320"/>
        </location>
        <ligand>
            <name>N-formimidoyl-L-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:58928"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="322"/>
        </location>
        <ligand>
            <name>N-formimidoyl-L-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:58928"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="323"/>
        </location>
        <ligand>
            <name>4-imidazolone-5-propanoate</name>
            <dbReference type="ChEBI" id="CHEBI:77893"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC90895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="410" mass="43856" checksum="EDAB6239AE6FFB69" modified="2018-07-18" version="1">MQTPQWDSLWLNVHLATMSDDASYGECRDGAIAVKDGVIAWLGSQSALPHNHSAKHIYDGKGAWLTPGLIDCHTHIVYGGNRSNEFEDRLNGVSYEEIAKRGGGIVATVTATRAASEAELFTQSLVRVMRLLQEGVTTLECKSGYGLDLATEAKILRVARQLGQELPVRISTTFLGAHAVPPEYAGRADAYIELVCEQMLPALVEEGLVDAVDAFCEKIGFSHAQTERVFQAAKKHGLPVKLHAEQLSDQGGAALTARYQGLSADHLEYLSDEGIAAMAEAGTVAVLLPGAYYFLRETKLPPLAALRAAAVPIAISTDCNPGTSPMTSLLLVMNMACTLFRMTPLEALQGTTRNAAKALGMSDKIGQLAVGMKADFALWDVDRPADLSYAIGANPCSGVVFDGRLLKING</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTD1</accession>
    <name>A0A2S9GTD1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4349</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000032">
        <property type="protein sequence ID" value="PRC90948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90948">
        <property type="protein sequence ID" value="PRC90948"/>
        <property type="gene ID" value="S2091_4349"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC90948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="477" mass="52756" checksum="EFE77849EBE3446F" modified="2018-07-18" version="1">MNAILAKLLRRLIRSQLQRSSPQKLLKLGEKKLLRSFHRAAQFSPAYQTLLAESSVQASQVRTPADFAQLCPLLEKTNTFRRFPIEQLIVANTKLADLASILTSSGHGQGGYALGISTRNQYNSTPFLIDLGLDLAFNVDSRRTLLINCLPMGVTFQSKALCVANVSVREDMACAIVKQTGHLFEQIILCGDPLFLKRLCDYSEELRLDWARYKMNVIIGEETFTESFRDYLAASLAINLSDANSGLIGSSMGVGELGLNLFNETRESIAIRRACVKNKTLLQDLMGDISSQAPLPTLLCFNPLRTYVEVVNRDASGNGDLVVSVLDTAAPVPLMRYKTGDRAKLIDADHLAQVLQKSILGLTAPALPLIALLGRSKDMLPGNWHVDHFKQVLYNNPNVARECSGAFRLSQREDGLLWEVQLRLDCPADPMLLADALSADLVLLGKEGAAKVHCLSYEKFPYGKTLDYERKFVYCSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTJ8</accession>
    <name>A0A2S9GTJ8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative glucoamylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_4237</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000030">
        <property type="protein sequence ID" value="PRC91049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91049">
        <property type="protein sequence ID" value="PRC91049"/>
        <property type="gene ID" value="S2091_4237"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11756">
        <property type="entry name" value="GH94N_ChvB_NdvB_1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11753">
        <property type="entry name" value="GH94N_ChvB_NdvB_2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009342">
        <property type="entry name" value="Carb-bd_put_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033432">
        <property type="entry name" value="GH36_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037824">
        <property type="entry name" value="GH94N_2_NdvB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037820">
        <property type="entry name" value="GH94N_NdvB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037018">
        <property type="entry name" value="Glyco_hydro_65_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010383">
        <property type="entry name" value="Glyco_hydrolase_94"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019282">
        <property type="entry name" value="Glycoamylase-like_cons_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17167">
        <property type="entry name" value="Glyco_hydro_36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06165">
        <property type="entry name" value="Glyco_transf_36"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10091">
        <property type="entry name" value="Glycoamylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01068">
        <property type="entry name" value="CBM_X"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="SSF48208"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="SSF74650"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="424"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="456"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="835"/>
            <end position="851"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="857"/>
            <end position="880"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="901"/>
            <end position="920"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="960"/>
            <end position="978"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="983"/>
            <end position="1003"/>
        </location>
    </feature>
    <feature type="domain" description="CBM_X" evidence="3">
        <location>
            <begin position="1605"/>
            <end position="1666"/>
        </location>
    </feature>
    <feature type="domain" description="CBM_X" evidence="3">
        <location>
            <begin position="2111"/>
            <end position="2176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC91049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="2912" mass="326637" checksum="ABFF4BECFC453129" modified="2018-07-18" version="1">MKIIDKNSLSNLLRLVGITRHSDWQGISDEGELPLRAELFGIVQMEEHGKVLARLHKVSKGKSKDLLLARLADNEIVLSEACNVLTVALKEGRQISPAAEWLLDNFYLIEEQIRTAKRHLPKGYSKELPRLISGTSDSHPRVYDIALQTISHGDGRIDPEGLSRFVASYQQITPLTLGELWAIPIMLRLALIENLRRVAARLVANRINCNLADTWADQMVETVEKDPSSLILLVADMARSDPPMVGSFVAELARRLQGQGPALTLPLTWIAPRLSEIGLTVEQLIQIEGQQMAADQVTISNSIGSLRLLGKMDWREFVETMSVVEQVLLRDPNDVYRLMDFATRDRYRHVIESISRRSELSEIQIAEQALFLAEQAAMTYGKDAVTAHIGYFLIGDGVPLLELAVPMKFSLYGLLCRSCSKSPLLTYLGAISLLSSLIIIGILVKAHLEAMQDWQLVVVAILSLLGVSQLAIGLVNWFVTIIVTPHQLPRLDFSKGITAECKTLVVVPTMLISVENINSLCEALEVRFLANQDEHIYYCLLTDFLDAATETTEEDASLLLQLGHKIEQLNEKYTSGGEGRFLLLHRARSWNAQEKIWMGRERKRGKLADLNAFLRNTGFNPFFCVVGNSDNLSSVKYIITLDTDTQLPRDSARQLIATIAHPLNQARFNPGQQRVAAGYGILQPRVSASLPSANASLYQRLCSGDSGIDPYTQAASDVYQDIFDEGSFIGKGIYNVDAFEQSLAGCCPDNQILSHDLLEGCYARSGLLTDVHVIEDYPKRYSNDVQRRHRWIRGDWQLIGWLLPHAPKVNAEELSKHNPLSALSRWKLFDNLRRSLVSTSLVLLLVCGWIMSPSPWFWSGIVLSILLIPPLTTSLLDLLRKSNDILVLQHLSASLRSTKQHLFHAALTLIFLPYDAFFSLDAILRTLWRLLISRRHLLEWTPSNQSNSNSDLSLTSSFRIMWFTSTLSIFLIIVLLLIHPASLFAAAGFLLAWLIAPAIAWYISEPHARSEAQLQDDQTVFLYRLARKIWSYYEILVGPEDNWLPPDNIQERPVAVVAHRTSPTNIGLALLANLTAYDFAYISVGQLLERSSNTLLSMRRMERYRGHFYNWYDTQSLKPLLPMYISSVDSGNLAGHLLTLRPGLLMLIDQPIVNQRLIGGIEDTFKIFQSLSGASSQIELMQFKTLLDFTSDASMMTLSNCQVMLQKLTIGAEDLVAVFGGKEDDQLTWWVSALLRQCRAMYDELLFLAPWSSWINSLEKNIMFSKIDFIPTLRELAGLEALWLSGNIIPKQNHNEANSNEEIRGIGELLALGSLRAATRIKEIESLALQASEFAQMDCSFLYDKATHLMTIGYAVAEQRCDSSYYDLLASEARLCTFVMIAQGQLPQESWFALGRQLTVAGGDPILMSWSGSMFEYLMPLLIMPTFENTLLDQTYHSVVQRQIEYGAQRDVPWGVSESGFHTFDASLNYQYRAFGVPGLGLKRGLGDDLVIAPYASMLAIMVDPEQACSNLQRLAKEGFEGKYGLYEAIDYTTSRLQRGQSYALIQSFMAHHQGMGLLSLAYYLRDRPMQKRFESDPLFQATMLLLQEKIPKASAFYANTIELADIRTNSEEQSMPMRIINRHETRVPEVQLLSNGRYNLMVTNAGGNNSHWKDLALTRWREDGTSDNWGSFCYVRDCESGEFWSTTYQPTLVKPDFYEVIFSEGRAEYRRRDHDIEMHTEIVVSPEDDIEMRRTHITNRSRVRRTIEVTSYSEIVLAPAAADNAHPAFSNLFVQTEILESQNAILSSRRPRSGDEKMPWMLNLIVAHGEEIKQISFETDRAKFLGRGNSTVAPAAMRVCGKLSGSQGSVLDPIASIRFQIDLAPQQIAVIDMVIGAAESREDALQLIAKYQDRFLADRVFELAWTHSQVVLRQLNATEADAQLYARLASSIIYANDQLRAEASILLKNRRGQSGLWSYAISGDLPIVLLQVKNLENIDLVRQMVQAHSYWRLKGLAVDLVIWNEDHAGYRQILQDQIMGMIASGIEAHSIDRPGGIFVRLADQMSSEDRILLQTVARVVLCDSRGTLAEQLNRRSIPELRMPQLNPTHPRAISIQNAIQAEENNLQFFNGLGGFSPDGKEYIITTETGNTTPAPWVNILANPRFGSVISESGQAYTWGENAHEFRLTPWNNDSVSDSCGEAFYLRDEESGHFWSPTPLPCRGQGPYVSRHGHGYSVFEHTEDGIHSELWVYVAIDASIKYSVLKIRNDSKTERKLSAVGYVELLLGDLRSKSAMHIVTESDPISGAIFAHNSYNTEFADRIAFFDVDAMNRTVSGDRAEFLGRNGALYNPAALSRTRLTGRVGAGLDPCAAIQVPFELSAGQEREIVFMLGVAGRRSADVSSLVYRYRGATAARKALEAVKAYWQNTLGAVQVETPDIALNLLANGWLMYQTIACRLWARSGFYQSGGAFGFRDQLQDVMALIHTEPHLVREHLLLSAAHQFVEGDVLHWWHPPTDRGVRTHCSDDYLWLPLATCRYVQSTGDTGILDEHAHFLEGRAVNAEEDSYYDLPTISTTSGTLYEHCVRAILRALRFGVHGLPLIGSCDWNDGMDKVGAEGKGESVWLGFFLYDVLMRFTEVAKLHGDFSFAGQCVDQAMQLQQKIEANAWDGNWYRRAYFDDGTPLGSISNAECQIDSISQSWAVLSGAGEISRTQTAMYEVSQRLVQRESGLIQLLEPPFDSSDLNPGYIKGYAPGVRENGGQYTHAAVWTIMAFAKMGDNKRAWELMDMINPINHAKTAHAVETYKVEPYVLAADVYAVSPHIGRGGWTWYTGSAGWMYRLIIESLLGLHLEVNTLTFKPCIPADWTSFTLKYRYRDTTYRITVVQIASDVAKQSVTVDGIDQPDCVIHLNNDALEHLVEIKMMTIGDALN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTL9</accession>
    <name>A0A2S9GTL9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Haloacid dehalogenase-like hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4239</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000030">
        <property type="protein sequence ID" value="PRC91051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91051">
        <property type="protein sequence ID" value="PRC91051"/>
        <property type="gene ID" value="S2091_4239"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="238" mass="27697" checksum="B6699E21342DCD03" modified="2018-07-18" version="1">MSAPEKIVFLLDVDNTLLDGDRIISDIDSHFYKVFGDEGRLRYWAIAESLRLELGYVDYLGAVQRFRSESKEDPRILMLSSFFLDYPFAERLYPRALDLLNHLLRWGNTVIVSDGDMIFQPRKIQRSGLWDAVEGRVLIYQHKEKMLEDIEQRFPSHHYVMVDDKLQILTAMKKIWHNRLTTIFPRQGHYALDPANIAAYPAADMSIEYIADLINTDVPALLHHTPLFTRNNHDGSTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTR4</accession>
    <name>A0A2S9GTR4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_4213</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000029">
        <property type="protein sequence ID" value="PRC91117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91117">
        <property type="protein sequence ID" value="PRC91117"/>
        <property type="gene ID" value="S2091_4213"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015562">
        <property type="term" value="F:efflux transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003423">
        <property type="entry name" value="OMP_efflux"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010131">
        <property type="entry name" value="RND_efflux_OM_lipoprot_NodT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02321">
        <property type="entry name" value="OEP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01845">
        <property type="entry name" value="outer_NodT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0564">Palmitate</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1134">Transmembrane beta strand</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015372362" evidence="2">
        <location>
            <begin position="23"/>
            <end position="478"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU362097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="478" mass="51410" checksum="506FD10078CAB234" modified="2018-07-18" version="1">MNKQLSNYSVSALLLSCLAACAVGPDYQKPDVAMPKGWQTNTSFHPAEPSDGVLKGNWWEMFGDEQLNQLEQQAAQHNQSLVVAAERLNQARLQVTASSSIQLPQVDLQASDARFKTSANRPLAVYGMPNSSVVQNNPQLGFAVGYEADLFGRVRRVVEGVKAAEGQATADFENTKLMLMSDLAADYFNLRELDVEIDIVEKGVVLQAKALDFIRIRHDLEAASGLDLAEQQALLDTNKTQLVLLQNQRSSVQNALSTLTGTPAPEFKLAPQVVKLVAPSLPVGLPADVLQRRPDVASAERAMAVANANIGVARAAYYPTIMLQANGGWDSNQMANLFNAPSILWSLGAGLTQHLFDAGKTTANVKIAESSYVAATANYRQSVLIAMQEVQTGIDSMAILNGANHQAEAAEASSARVLELANDRYTGGLDIYLNVISAQQSLLASQRQAVQIHGQQMLNAVYLVKALGGGWQGMVAAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTU9</accession>
    <name>A0A2S9GTU9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Alkyl sulfatase and related hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_4134</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the metallo-beta-lactamase superfamily. Type III sulfatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000028">
        <property type="protein sequence ID" value="PRC91133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91133">
        <property type="protein sequence ID" value="PRC91133"/>
        <property type="gene ID" value="S2091_4134"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018741">
        <property type="term" value="F:alkyl sulfatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018909">
        <property type="term" value="P:dodecyl sulfate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07710">
        <property type="entry name" value="arylsulfatase_Sdsa1-like_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038536">
        <property type="entry name" value="Alkyl/aryl-sulf_dimr_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029229">
        <property type="entry name" value="Alkyl_sulf_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029228">
        <property type="entry name" value="Alkyl_sulf_dimr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044097">
        <property type="entry name" value="Bds1/SdsA1_MBL-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036527">
        <property type="entry name" value="SCP2_sterol-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14864">
        <property type="entry name" value="Alkyl_sulf_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14863">
        <property type="entry name" value="Alkyl_sulf_dimr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55718">
        <property type="entry name" value="SSF55718"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015621644" evidence="5">
        <location>
            <begin position="24"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="domain" description="Lactamase_B" evidence="6">
        <location>
            <begin position="128"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00033751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC91133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="672" mass="73449" checksum="F795F420E2CB7632" modified="2018-07-18" version="1">MKKIMKINAITASLLFIMSTAQAQLLNAPKDAEPATIAKNAETARHLPPADPQIDADIAHGFIGSIPDAATIGAQGNVVYTLKGYEFLQAEKAPATVNPSLWIQARKGMGNGLYKVTDGFYQVRGIDLTNMTIVEGKTGIIIIDAMLSTETARSALNLYYSHRPKKPIVAILYNHSHVDHYGGVKGLVSEEDVKSGKVQIIAPTGFMEHAISENVLAGNAMSRRAEYQFGTSLPRSDRGQLDIGGAKALSKGTITLIEPTRYVTQAVEKMVIDGVEIINMLTPGTEAPAEMIHFFPQFKVLDTGELACQTQHQLLTLRGASIRDAQAWSNYLNQALARFGDDTTMLVGQHTWPVIGHTRVINYLSKQRDMYKWLNDQSLRLINLGYKPVEVAEFMSKNVPASLANEWETQGYYGSVQRNAKAVYQEYIGWYDGNPANLDALSDADYGRKFVAYGGGAEAILKRAHADYVQGEYRWVAQAMSHLVFADPSNQEARNLGADALEQLGYQAQSAVERNAYLYGAMELRNGKKTPVAGELRTDSADTVKALSIDNIFDYLGVRLNAPKAEGKHIVINWNFSDGDAAGKNDLHYVLNLENSALTYLVGKQSTTADATLTLSRATLDAILLQKLSPKQAIATGLIKIDGNPQAFGMLLSLMDTFSPTFNIVTPNPVLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GU27</accession>
    <name>A0A2S9GU27_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transglycosylase SLT domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_4108</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000027">
        <property type="protein sequence ID" value="PRC91213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91213">
        <property type="protein sequence ID" value="PRC91213"/>
        <property type="gene ID" value="S2091_4108"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023346">
        <property type="entry name" value="Lysozyme-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008258">
        <property type="entry name" value="Transglycosylase_SLT_dom_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01464">
        <property type="entry name" value="SLT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53955">
        <property type="entry name" value="SSF53955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="domain" description="SLT" evidence="2">
        <location>
            <begin position="141"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="290" mass="30988" checksum="0BD7ADEC9A9B9279" modified="2018-07-18" version="1">MFQQMFNSAPSFSEPSAPLQIIVSKQRNTLITILHHTMMVLGIAAITALGLMFVKPELTDEFQAISPFFKEAADIDEPAPVSLATIATDTAINQAANAADAQLIGDAKQQRSVTNWLSKRYRVANDATDMLVSAAYLTAKEIKLDPLLILSVMAIESGLNPFAESPVGAQGLMQVMSKVHQEKFDDLGGVKAALNPVANIRVGAQILKEYVTRGGSVEAGLKLYVGAAMSDSDGGYGNKVIAEYKRLKDVANGKSVPTFTVNTVNASITAKPAIIKVNETRVEAEHLAAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GU76</accession>
    <name>A0A2S9GU76_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Multidrug resistance efflux pump</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3953</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000025">
        <property type="protein sequence ID" value="PRC91282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91282">
        <property type="protein sequence ID" value="PRC91282"/>
        <property type="gene ID" value="S2091_3953"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039562">
        <property type="entry name" value="MFP_biotin_lipoyl_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13533">
        <property type="entry name" value="Biotin_lipoyl_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="18"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="domain" description="Biotin_lipoyl_2" evidence="2">
        <location>
            <begin position="56"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="407" mass="43471" checksum="3BA42625483D6602" modified="2018-07-18" version="1">MTTETEQLMPAKAQRKTALLAITGVVGIAAIAYGVYWYINNGKHETTDNAYVQGNVVQITPQIAGTVSAIGAQDTDFVRAGQSVVQLDGADAQVALDQARAQLAQTVREVRTIYANNSTLSANVSLREAEITRTNSELARAKDDLARRQAVASIGAVSNEELQHAKANLVAAQSAQTAAAAGVLSANEQLSSNKTLTEGVSVEHHPNVMRAAAKFREAYINAQRTNLLSPVTGYVARRSVQLGQRIQAGTPLMAVIPMDQLWVDANFKEVQLRKMRIGQPVTLISDVYGKSVTYHGSIEGLGVGTGAAFALLPAQNATGNWIKVVQRVPVRIKLDAKELADHPLRIGLSMEVEVEITDQSGKALADTANNEKKAEVITTDNTVVDAEIKKIIASNLGEKSAKADKAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GU88</accession>
    <name>A0A2S9GU88_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4058</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000026">
        <property type="protein sequence ID" value="PRC91273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91273">
        <property type="protein sequence ID" value="PRC91273"/>
        <property type="gene ID" value="S2091_4058"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007434">
        <property type="entry name" value="FemAB-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04339">
        <property type="entry name" value="FemAB_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="388" mass="44211" checksum="A55FD07390D0A843" modified="2018-07-18" version="1">MQLANYRTAVIKNLSEISAGQWEQLRTAAFNGDANPFLSYAYLSALEESGCACAATGWSTHFLTIWQGDQLHAALPMYLKSHSYGEYVFDWAWAQAFEEHNLPYYPKLLAAIPFTPVTGPRLLALNEPAMRALLNALVQHSESGLTSSCHILFTPEQQAQQLQEAGFMPRFGVQFHWTNFGYRDFSDFLAQLEAKKRKNILAERRKVRDAGIHFTVKVGQQISASDWGFFVKCYNSTYRQHGGSGYLNLDFFLRIAASMPQNLLMITAIRDRQPIAASLLFHNEQTVYGRYWGCVEYHPCLHFETAYYQPMEFCIANNIRHFDGGAQGEHKMARGFLPKTTYSVHKISHPAFADAVERFLVREQVGINSYINELHEHNPFAVRSKNTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GU90</accession>
    <name>A0A2S9GU90_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Biopolymer transport protein ExbD/TolR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_4121</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the ExbD/TolR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000027">
        <property type="protein sequence ID" value="PRC91226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91226">
        <property type="protein sequence ID" value="PRC91226"/>
        <property type="gene ID" value="S2091_4121"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003400">
        <property type="entry name" value="ExbD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02472">
        <property type="entry name" value="ExbD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC91226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="79" mass="8673" checksum="7BE7EB6DA81AFBA9" modified="2018-07-18" version="1">MVNIDIDFDGTILWDGNVIPDHASLEEHMRAVAAIPDQPEMHLRPNKLVAYKTVASVMAAAQRLGVTKIGMVGNEQFVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUK5</accession>
    <name>A0A2S9GUK5_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">YcaO domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4007</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000025">
        <property type="protein sequence ID" value="PRC91336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91336">
        <property type="protein sequence ID" value="PRC91336"/>
        <property type="gene ID" value="S2091_4007"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003776">
        <property type="entry name" value="YcaO-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041080">
        <property type="entry name" value="YcaO_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02624">
        <property type="entry name" value="YcaO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18381">
        <property type="entry name" value="YcaO_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00702">
        <property type="entry name" value="TIGR00702"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51664">
        <property type="entry name" value="YCAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YcaO" evidence="1">
        <location>
            <begin position="61"/>
            <end position="434"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="579" mass="64999" checksum="AA3C0FA320DF75E0" modified="2018-07-18" version="1">MQTESFIPGKDASLESTIATMSAKLASRGFVLNESSLLNEIEGIWSTHVKDNDCPMLFANGKGSSELAARASAFGEFFERLGTHYFWTHFYLGKTRANRPFVHYPQERWFAPGPDASWPDELLNPTLREFYNPDDGIGAEVLVDLNSGNVERGICALPYKRLSDGEQTWIPVNIIGNLYVSNGMAAGNTMMEARSQALSEIFERHIKYRIISEGLCLPEVPDEVIARFPKIAAGIAGLRKAGFGILVRDASLDGKYPVMCVTLLHPKDQGIFASFGAHPRFEIALERALTELLQGRALNTLEGFPAAGFDMDEINAVANLEIHFVDSSGVMSWKFLRDTPDFPFADWNFSNTTAEDYAWLCNAIHAEGYEIYIADFEEQGAYSCRILVPGMSEIYPVEDLEWENNSIGNQIRPALVRLNELSEAECRTLLDDLQTMNVSEERPLWEILGLAAQVGSAWKQLRIGELKTLLALAIGDRDGILEGCEWIHHFNDLSADRRLVYRCIESILKLEELEDEDEEAREDYLRPLILLFGEENFRLAEALLDRSERFFGLVTLGDDYQGSAMHQTLLAAYDKLFAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUL0</accession>
    <name>A0A2S9GUL0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Geranylgeranyl pyrophosphate synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3938</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the FPP/GGPP synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000024">
        <property type="protein sequence ID" value="PRC91393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91393">
        <property type="protein sequence ID" value="PRC91393"/>
        <property type="gene ID" value="S2091_3938"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008299">
        <property type="term" value="P:isoprenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00685">
        <property type="entry name" value="Trans_IPPS_HT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000092">
        <property type="entry name" value="Polyprenyl_synt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033749">
        <property type="entry name" value="Polyprenyl_synt_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00348">
        <property type="entry name" value="polyprenyl_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="SSF48576"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00723">
        <property type="entry name" value="POLYPRENYL_SYNTHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00444">
        <property type="entry name" value="POLYPRENYL_SYNTHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU004466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="309" mass="33834" checksum="6CCF515866E8A2DE" modified="2018-07-18" version="1">MDAVNTVIRVKLQSEVPLVNQVGEYIINAGGKRIRPVLAVLFANAHGYQGTAHHNLAAIIEFIHTATLLHDDVVDESSLRRGRKTANALFGNAASVLVGDFLYTRSFQMMVELQSMRIMEILADATNIIAEGEVLQLLNMHDPDVTEERYLQVIRSKTAKLFEAATGLGALIAGANEAEIEAAAEYGRSLGTAFQLIDDVLDYSGNAADIGKNVGDDLREGKPTLPLIYLMRHGTEHQCELVRQCIENGDSSKFDEILSAITESGALAYSRAQAEQASDRAIQALTHLPESDYKDSLIQLARFSIDRNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUT5</accession>
    <name>A0A2S9GUT5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Disulfide bond chaperones of the HSP33 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_3749</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000022">
        <property type="protein sequence ID" value="PRC91471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91471">
        <property type="protein sequence ID" value="PRC91471"/>
        <property type="gene ID" value="S2091_3749"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00498">
        <property type="entry name" value="Hsp33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.480">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.55.30.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000397">
        <property type="entry name" value="Heat_shock_Hsp33"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016154">
        <property type="entry name" value="Heat_shock_Hsp33_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016153">
        <property type="entry name" value="Heat_shock_Hsp33_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023212">
        <property type="entry name" value="Hsp33_helix_hairpin_bin_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30111">
        <property type="entry name" value="PTHR30111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01430">
        <property type="entry name" value="HSP33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005261">
        <property type="entry name" value="Heat_shock_Hsp33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118352">
        <property type="entry name" value="SSF118352"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64397">
        <property type="entry name" value="SSF64397"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC91471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="315" mass="34831" checksum="A4AC60930EDE6351" modified="2018-07-18" version="1">MTDTLQKFMFDDATVRGELVELNATWKQVLTHHNYPLPVQNLLGELTCAAALLCANLKFDGSMIMQIHGEGAIKLLVVECDNQLQVRAMAKLAENAHIADNASLSELVNANGHGRFVITLDPNNKVPGQQAYQGIVPLEGDSIAAVIENYMKQSEQLDTKLWLASDSEVSRGMLLQRLPCHGGSATHATHDEELSQAESAEQAWTRACLLGNTLKRDELLSASTATLLHRLFWEETLRIFEPQDITFSCSCSREKVGNMLVMLGKEEVTEAVNSLGKLDINCDFCGKPYSFDAVDCTQLFLSPEIKINPEVDRTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUU0</accession>
    <name>A0A2S9GUU0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Metallo-beta-lactamase superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3775</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000022">
        <property type="protein sequence ID" value="PRC91497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91497">
        <property type="protein sequence ID" value="PRC91497"/>
        <property type="gene ID" value="S2091_3775"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015727824" evidence="1">
        <location>
            <begin position="46"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="domain" description="Lactamase_B" evidence="2">
        <location>
            <begin position="107"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="339" mass="36301" checksum="52B6BC8E5641B4E6" modified="2018-07-18" version="1">MFALHTTPPPKQENALISTALLRSTTFAVITALATLSLTTSPAHAAAPMVKTSAPGYYRVMLGDFEVTALSDGTLQLPMDKALTNINPADFNTALKKFHITNPIETSFNGYLINTGSKLVLIDTGAGKFFGATLGKLAASLKAAGYQPEQVDEIYITHMHGDHIGGLTVDGVAAFPNAIVRADKHEADYWLSQAQLDKAAADDKGGFQHAMEAFQPYIKAGKFKPFDGNTDLTPGIKAVAAYGHTPGHTTYLVESKGQKLMLWGDLMHVAAAQFDKPSVAINFDHDNKAAIAERKKAYADAAQQGYMVGSAHLSFPGLGYLRAEGKGYAWIPVNYVSLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUU2</accession>
    <name>A0A2S9GUU2_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ</fullName>
            <ecNumber evidence="5">2.1.1.200</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">tRNA (cytidine(32)/uridine(32)-2'-O)-methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">tRNA Cm32/Um32 methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">trmJ</name>
        <name evidence="7" type="ORF">S2091_3883</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>S-adenosyl-L-methionine + uridine(32) in tRNA = 2'-O-methyluridine(32) in tRNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42936"/>
            <dbReference type="Rhea" id="RHEA-COMP:10107"/>
            <dbReference type="Rhea" id="RHEA-COMP:10290"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74478"/>
            <dbReference type="EC" id="2.1.1.200"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>cytidine(32) in tRNA + S-adenosyl-L-methionine = 2'-O-methylcytidine(32) in tRNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42932"/>
            <dbReference type="Rhea" id="RHEA-COMP:10288"/>
            <dbReference type="Rhea" id="RHEA-COMP:10289"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74495"/>
            <dbReference type="ChEBI" id="CHEBI:82748"/>
            <dbReference type="EC" id="2.1.1.200"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.200" evidence="5"/>
    <dbReference type="EMBL" id="PUGF01000023">
        <property type="protein sequence ID" value="PRC91468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91468">
        <property type="protein sequence ID" value="PRC91468"/>
        <property type="gene ID" value="S2091_3883"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008173">
        <property type="term" value="F:RNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004384">
        <property type="entry name" value="RNA_MeTrfase_TrmJ/LasT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001537">
        <property type="entry name" value="SpoU_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42786">
        <property type="entry name" value="PTHR42786"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00588">
        <property type="entry name" value="SpoU_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004808">
        <property type="entry name" value="LasT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="SSF75217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00050">
        <property type="entry name" value="rRNA_methyl_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 7" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="SpoU_methylase" evidence="6">
        <location>
            <begin position="15"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC91468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="250" mass="27524" checksum="A10B7DE8014EC3CE" modified="2018-07-18" version="1">MHTPALSTPSSFDRLRFVLVETSHPGNVGSVARAMKTMGYSSLYLVNPRFPDVLSHPEAIALASGAQDILENAIIVSTIQEALQGCEIAAAVSARLREFSPPIIDPREFAQLFNKPETGYAALVLGNERTGLLNELVEKCTYLINIPANPAYSSLNLAQAVQVLAYECRYGSMESKIIDTEIGFKGDSANLADIDAMFNHLEQGLIAINFIDPDRPKKLMSRLKRLFARTQLETEEVNILRGIAKKMLDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GV27</accession>
    <name>A0A2S9GV27_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF4124 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3680</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000021">
        <property type="protein sequence ID" value="PRC91564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91564">
        <property type="protein sequence ID" value="PRC91564"/>
        <property type="gene ID" value="S2091_3680"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025392">
        <property type="entry name" value="DUF4124"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13511">
        <property type="entry name" value="DUF4124"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015759718" description="DUF4124 domain-containing protein" evidence="1">
        <location>
            <begin position="23"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4124" evidence="2">
        <location>
            <begin position="12"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="206" mass="23803" checksum="DD8CCF2CFBD7789A" modified="2018-07-18" version="1">MTKTQLQFLPILFVLHLASAHADIYSCKDSAGHMITSDRPIPECANRSTQIYGNNGSLKQEFAAELTPEQKRAAELKEQQRVKEAQQQEQLKKEQRYLIAHYPNEQSVEIARHQAVDVLEAKIKVEKHLIEVTTAALNKNREEQLHIPQNQTNKIIAAQNQEDDLAQTIEHSEHLIHNYQIEEIKINLQFDETHRRYLEIVAPSKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVF3</accession>
    <name>A0A2S9GVF3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative thioesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3616</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000020">
        <property type="protein sequence ID" value="PRC91678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91678">
        <property type="protein sequence ID" value="PRC91678"/>
        <property type="gene ID" value="S2091_3616"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="145" mass="16466" checksum="BCDFACF5640D5CB8" modified="2018-07-18" version="1">MTTVGNTQQNQQSELKLVYTCCMPVRWGDMDAFGHVNNTVYFRYMEQARIEWMASFLDVASASNTGPVLINAQCNFLRSLKYPDQIEVQMFIAAPGRSSFNTHYQIYRLGAEKTRCAEGQAKVVWVDTVQEKSAPLPEAVLAQFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVQ9</accession>
    <name>A0A2S9GVQ9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3564</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000019">
        <property type="protein sequence ID" value="PRC91809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91809">
        <property type="protein sequence ID" value="PRC91809"/>
        <property type="gene ID" value="S2091_3564"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010374">
        <property type="entry name" value="DUF969"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06149">
        <property type="entry name" value="DUF969"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="26"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="63"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="162"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="196"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="230" mass="24812" checksum="4B5A72A2ABAC11B1" modified="2018-07-18" version="1">METVNLWPLIGVAVVIAGFVLRTNPVLVVIISAIATGLAAHLPLDKILALLGSGFIKTRNLPLIFFLPLAAIGLSERFGLKEHAQSSIAKIRSATAGRLLIVYLFIREISAAMGLTSLGGHPQMVRPLIAPMAEAATQNQYGVVPEKLRHKIRAMSAATDNVGLFFGEDVFVAFGAIILMQTILRNEGIEVNAIHMALWGIPTAVSAFVIHSWNLHRLDKQIARELGRGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVS4</accession>
    <name>A0A2S9GVS4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3569</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000019">
        <property type="protein sequence ID" value="PRC91814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91814">
        <property type="protein sequence ID" value="PRC91814"/>
        <property type="gene ID" value="S2091_3569"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015755503" evidence="1">
        <location>
            <begin position="22"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="319" mass="36099" checksum="23C45C0D31ADD062" modified="2018-07-18" version="1">MKFSNSYIAVAFFFISLVGCAKPGSSEYFKYTVQGTYNNKPISYSQYYKCSQFVQPTEGPDAPLHLRWESEGLDRAAIQLDMSHTLILRGDQSFCLDRAARELNQPIAMLEASDNLIKLYIVRGNAKNSLLSIDRVKIEPTNESTDHLGPTESQVALANAILAKYKNRFENVQATYIPYYVWATTGNSQNYFKSLTEVVVAKVDEAPPVSGRSDMFVRFPFYRDRAYRLIDGKVSDLIHKELVYADHFFELVNTPQDDGTVFYSSKEMDRSVDAIVNYKGTIVSVKTMQEAYDPETKNIISFMHQSAPDLAGVLNVFAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVU1</accession>
    <name>A0A2S9GVU1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putative threonine efflux protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_3374</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000018">
        <property type="protein sequence ID" value="PRC91818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91818">
        <property type="protein sequence ID" value="PRC91818"/>
        <property type="gene ID" value="S2091_3374"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001123">
        <property type="entry name" value="LeuE-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30086">
        <property type="entry name" value="PTHR30086"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01810">
        <property type="entry name" value="LysE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006324">
        <property type="entry name" value="LeuE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="40"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="70"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="113"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="147"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="192"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC91818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="214" mass="22751" checksum="A3DFBA1E680A6609" modified="2018-07-18" version="1">MPLATWITFLFVSLAATFSPGPGVLLAISTSVTLGARRTLYSSAGNALGVFIVATVAITGLGLLLQTSTMAFSVLKIIGAGYLIYLGVRQWRSKAAAAQPKTTTAIASTRSKVFLHGLLVALTNPKAILFFTAIFPQFIQTSHPDPVRFLLLTSTFVVCVVTSHLFYITLATRMGSSIIGTNGMMGTTRMRYLNRASGLIFIGLGCAVLTITSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GW08</accession>
    <name>A0A2S9GW08_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">UDP-2,3-diacylglucosamine hydrolase</fullName>
            <ecNumber evidence="9">3.6.1.54</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">UDP-2,3-diacylglucosamine diphosphatase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">lpxH</name>
        <name evidence="11" type="ORF">S2091_3447</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>H2O + UDP-2-N,3-O-bis[(3R)-3-hydroxytetradecanoyl]-alpha-D-glucosamine = 2-N,3-O-bis[(3R)-3-hydroxytetradecanoyl]-alpha-D-glucosaminyl 1-phosphate + 2 H(+) + UMP</text>
            <dbReference type="Rhea" id="RHEA:25213"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="ChEBI" id="CHEBI:57957"/>
            <dbReference type="ChEBI" id="CHEBI:78847"/>
            <dbReference type="EC" id="3.6.1.54"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="9">Binds 2 Mn(2+) ions per subunit in a binuclear metal center.</text>
    </comment>
    <comment type="pathway">
        <text evidence="9">Glycolipid biosynthesis; lipid IV(A) biosynthesis; lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 4/6.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell inner membrane</location>
            <topology evidence="9">Peripheral membrane protein</topology>
            <orientation evidence="9">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the LpxH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.54" evidence="9"/>
    <dbReference type="EMBL" id="PUGF01000018">
        <property type="protein sequence ID" value="PRC91891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91891">
        <property type="protein sequence ID" value="PRC91891"/>
        <property type="gene ID" value="S2091_3447"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00359">
        <property type="reaction ID" value="UER00480"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019897">
        <property type="term" value="C:extrinsic component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008758">
        <property type="term" value="F:UDP-2,3-diacylglucosamine hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009245">
        <property type="term" value="P:lipid A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00575">
        <property type="entry name" value="LpxH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP_ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043461">
        <property type="entry name" value="LpxH-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010138">
        <property type="entry name" value="UDP-diacylglucosamine_Hdrlase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34990">
        <property type="entry name" value="PTHR34990"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34990:SF1">
        <property type="entry name" value="PTHR34990:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01854">
        <property type="entry name" value="lipid_A_lpxH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="1 9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 9" id="KW-0441">Lipid A biosynthesis</keyword>
    <keyword evidence="2 9" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="6 9" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8 9" id="KW-0464">Manganese</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallophos" evidence="10">
        <location>
            <begin position="28"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="9">
        <location>
            <begin position="104"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="32"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="34"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="65"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="104"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="139"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="147"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="185"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="191"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="194"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="223"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="225"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC91891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="278" mass="31109" checksum="4AE380A819572043" modified="2018-07-18" version="1">MSDSSSKAASKAANQDADQLARPKAVALFISDLHLQAEMPATTAAFLTFLEQHGTKAEQLYLLGDIFEYWAGDDDLSSPFPQQIAQALRRVSDAGVALFWMAGNRDFLVGNAFSAATNATLLTDPHILEYNSQRYLITHGDQLCTDDIAYQTFRAQVRQPEWQTAFLARPLAERKALISAMRRQSQLHQKEQMQHSEMIMDVNLEAVSKLFASSNTHTMIHGHTHRPALHRDEGNSRYVLSDWDRDTDSGHLRGDWLALQADGSLQRYNALGNPVTSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GW89</accession>
    <name>A0A2S9GW89_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Beta-lactamase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3325</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000017">
        <property type="protein sequence ID" value="PRC91983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91983">
        <property type="protein sequence ID" value="PRC91983"/>
        <property type="gene ID" value="S2091_3325"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015610288" evidence="1">
        <location>
            <begin position="23"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-lactamase" evidence="2">
        <location>
            <begin position="57"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="498" mass="54955" checksum="656FB811589D0D39" modified="2018-07-18" version="1">MRAKLLLIGFMFCFLSIQFVQAQESERSNDIRTAVPQTSTISDDPEVLGSERLFSAWMEGQIAYRGLPGIAIGVVSDQKLVWAKGFGFADIKVKLPMTPETKFRIASNSKLFTAIAIMQLREQGKLGLDDPVVKYLPWFTPKPAGDDDGPITIEQLLSHSSGLQREASDHWSSLQFPTSEELQRLLSDRQATFAPSVRWKYSNLGFAIAGDVVEKVSGQKWADYVTQNIFKPLGMNDSSVDKNVAGLAVPYGRRMPDGSRAIFPFVDAKGMGSATGVTSDVNDLAKFISAQFRRGPRGGAQIVSGGSWREMLRVRSVEENWTTGSGLGFDMRRVKDKTYIGHKGGYFGNTTQTLIQLDDKVGVIVLTNTNDSDPSDIAQQLMATVGQAVAKAAKEKTVQVEWDASWERYAGLYRGYWGDSKFVLGDSQVVLLNKKLVIITPNGQNLDNPVSLEPLGNGKFRFMATTGGDVAGEVVRFEEVKDKPMRMYTGDSWLDRVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWC4</accession>
    <name>A0A2S9GWC4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Lysine efflux permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_3364</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000017">
        <property type="protein sequence ID" value="PRC92022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92022">
        <property type="protein sequence ID" value="PRC92022"/>
        <property type="gene ID" value="S2091_3364"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001123">
        <property type="entry name" value="LeuE-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30086">
        <property type="entry name" value="PTHR30086"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01810">
        <property type="entry name" value="LysE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="34"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="63"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="105"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="149"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="185"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC92022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="206" mass="22544" checksum="B5D224320F05FEB1" modified="2018-07-18" version="1">MQNPSIVLQGFLFGIGLFAAMGPKDSFLIKQALIGRYLPILVFICVASDILLITLGVAGIGRLVAQSAGLLTVAVWGGAAYLFWYGGKTLLAALTNKSMPSDTKVDYGTSLRSVCLTALTLSLFNPYALIDTLLVIGPISGSMPDDVRWFFAFGAMMASLLWFSVLTIGTTFLRRFFLQAVMWRVLDTIIASIMFYLGIQLLLFYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWD9</accession>
    <name>A0A2S9GWD9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3353</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000017">
        <property type="protein sequence ID" value="PRC92011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92011">
        <property type="protein sequence ID" value="PRC92011"/>
        <property type="gene ID" value="S2091_3353"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001845">
        <property type="entry name" value="HTH_ArsR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00778">
        <property type="entry name" value="HTHARSR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00418">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50987">
        <property type="entry name" value="HTH_ARSR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH arsR-type" evidence="1">
        <location>
            <begin position="1"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="115" mass="12196" checksum="4456E3746E060C1E" modified="2018-07-18" version="1">METKNVISALAALAQESRLAVFRALVQAGPEGMAATKISEHVGVPPSSLSFHLKEMSYADLITSRQEGRFVIYSANFITMNGLIGFLTENCCGGNPCSPVCTPKSTSAKISEVAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWE6</accession>
    <name>A0A2S9GWE6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Peptidase family S41</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_3178</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000016">
        <property type="protein sequence ID" value="PRC92043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92043">
        <property type="protein sequence ID" value="PRC92043"/>
        <property type="gene ID" value="S2091_3178"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005151">
        <property type="entry name" value="Tail-specific_protease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03572">
        <property type="entry name" value="Peptidase_S41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="SSF50156"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015524216" evidence="2">
        <location>
            <begin position="24"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="domain" description="TSPc" evidence="3">
        <location>
            <begin position="284"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC92043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="548" mass="57125" checksum="4F218768E6C5DC14" modified="2018-07-18" version="1">MIGKKLKKIIIPMLLAATLSACGGGGGGSSSNTSSGTSGSTGFPPSTSLAEQCAVPRPAGTINPVTGQPYNDVQGSLTTEMAWIASYVNETYLWYNEVPVVSSSPYVLNATVPYVNPTTNGQSTETLASNYDVVDAYFNSQRTPLFTASGKPKDQFHFTYTTAAWQALSAAGNQAGFGFEVALLSASPPRQALVAYTSPGTTATQNNVQRGAQILTVNGVDVANGTDLATLNEGLFSPVAGTSYTFQILDQGSSTPRTITMTAANITLTPVQNVGTLPAPNTSVGYILYNDQIATAESELIAAVNQLKAANNGAGISDLVLDIRYNGGGFLDLASEMAFMIASPAATSGTVFEQDTYNNKNPFNFTTAQTTVPFFSVSQGFSTSIPAGQALPQLGLSTVYVITGAGTCSASEAIMNGLLGVGVKVIQIGATTCGKPYGFFPQDNCSTTYFAIQFEGVNNLGFGAYADGFIPGGTGSTANNLPGCPIGDDFSKQLGDPTEARLAAALQYRNTGTCPAPSATILKQLKQNEPILKRSPARENRILRKQLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWF0</accession>
    <name>A0A2S9GWF0_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ribose-5-phosphate isomerase A</fullName>
            <ecNumber evidence="2">5.3.1.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Phosphoriboisomerase A</fullName>
            <shortName evidence="2">PRI</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">rpiA</name>
        <name evidence="3" type="ORF">S2091_3370</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>aldehydo-D-ribose 5-phosphate = D-ribulose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:14657"/>
            <dbReference type="ChEBI" id="CHEBI:58121"/>
            <dbReference type="ChEBI" id="CHEBI:58273"/>
            <dbReference type="EC" id="5.3.1.6"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate degradation; pentose phosphate pathway; D-ribose 5-phosphate from D-ribulose 5-phosphate (non-oxidative stage): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ribose 5-phosphate isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.6" evidence="2"/>
    <dbReference type="EMBL" id="PUGF01000017">
        <property type="protein sequence ID" value="PRC92028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92028">
        <property type="protein sequence ID" value="PRC92028"/>
        <property type="gene ID" value="S2091_3370"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00115">
        <property type="reaction ID" value="UER00412"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004751">
        <property type="term" value="F:ribose-5-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009052">
        <property type="term" value="P:pentose-phosphate shunt, non-oxidative branch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01398">
        <property type="entry name" value="RPI_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00170">
        <property type="entry name" value="Rib_5P_isom_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020672">
        <property type="entry name" value="Ribose5P_isomerase_typA_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004788">
        <property type="entry name" value="Ribose5P_isomerase_type_A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11934">
        <property type="entry name" value="PTHR11934"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06026">
        <property type="entry name" value="Rib_5-P_isom_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00021">
        <property type="entry name" value="rpiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2 3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="28"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="81"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="94"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="103"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="121"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="223" mass="23253" checksum="0B987E7487772823" modified="2018-07-18" version="1">MTQDELKQAVARAAIQYVVAGQIVGVGTGSTANFFIDELAKIKDKIPGAVASSEATAARLRSHGIKVLDLNEVTSMPVYIDGADEIDASGAMIKGGGAALTREKIVASVAEKFVCIADGSKLVNVLGKFPLPIEVIPMAQAVVARQLSLLGGEPKLRMKDGKPLLTDNGNVILDVHELEITNPVAMEAVMNNIVGVVTVGLFAKQGANVCLLGMADGVKTLTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWI2</accession>
    <name>A0A2S9GWI2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Fatty acid desaturase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">S2091_3209</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000016">
        <property type="protein sequence ID" value="PRC92074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92074">
        <property type="protein sequence ID" value="PRC92074"/>
        <property type="gene ID" value="S2091_3209"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016717">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03505">
        <property type="entry name" value="Delta9-FADS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015876">
        <property type="entry name" value="Acyl-CoA_DS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005804">
        <property type="entry name" value="FA_desaturase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002560">
        <property type="entry name" value="Transposase_DDE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11351">
        <property type="entry name" value="PTHR11351"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01610">
        <property type="entry name" value="DDE_Tnp_ISL3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00487">
        <property type="entry name" value="FA_desaturase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="71"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="194"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="domain" description="FA_desaturase" evidence="8">
        <location>
            <begin position="68"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="domain" description="DDE_Tnp_ISL3" evidence="9">
        <location>
            <begin position="319"/>
            <end position="446"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC92074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="447" mass="51551" checksum="2B363FB836D38128" modified="2018-07-18" version="1">MLVGSFWLSISKFEYNTVQVKNNSGVKSSYLASHRATETSFKQELNILSNFMTAALDFLANGFTRASGWEVFIFTMIVTHITIVSVTIFLHRCQAHRALDLHALPSHFFRFWLWLTTGQVTKEWASIHRKHHAKCETEEDPHSPVTRGIKKVFWQGAELYRAESKNKETMTKYGHGTPDDWIERNLYTRFSWQGVALMLVINIMLFGVIGITVWAVQMLWIPVNAAGIINGIGHYWGYRNYDCADASTNILPIGILIGGEELHNNHHTFGTSAKFSSKWYEFDIGWFYIRIMQMCGLATVKKVAPEPKLLAKNTVVDQMTLQSVIANRYEVMAKYTKSLKKMWRVELEHLRDKAKLEDAFLASSKKLLQCEPAKLQAVDMQQLKELFAHSKALKTMHEMRVELNVIWDRSNDTREQLVQKLQDWCARAEASGIQALEEFAFRLRRYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWJ0</accession>
    <name>A0A2S9GWJ0_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Oligoribonuclease</fullName>
            <ecNumber evidence="1">3.1.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">orn</name>
        <name evidence="3" type="ORF">S2091_3368</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">3'-to-5' exoribonuclease specific for small oligoribonucleotides.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the oligoribonuclease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="1"/>
    <dbReference type="EMBL" id="PUGF01000017">
        <property type="protein sequence ID" value="PRC92026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92026">
        <property type="protein sequence ID" value="PRC92026"/>
        <property type="gene ID" value="S2091_3368"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000175">
        <property type="term" value="F:3'-5'-exoribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06135">
        <property type="entry name" value="Orn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00045">
        <property type="entry name" value="Oligoribonuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013520">
        <property type="entry name" value="Exonuclease_RNaseT/DNA_pol3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022894">
        <property type="entry name" value="Oligoribonuclease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11046">
        <property type="entry name" value="PTHR11046"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00929">
        <property type="entry name" value="RNase_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00479">
        <property type="entry name" value="EXOIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0540">Nuclease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Exonuclease" evidence="2">
        <location>
            <begin position="19"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="193" mass="22049" checksum="9DBC8D178E230F24" modified="2018-07-18" version="1">MSQASILPATPVVKPNEFNLVWLDMEMTGLDPDTDRIIEVAVIVTDMELNILAEGPVFAIHQSDETLDKMDNWNKGTHGRSGLIDRVKASTVTEAEAEIALIAFLKKYVPAGKSPMCGNSICQDRRFMVRGMPKLEAYFHYRNLDVSTIKELCRRWKPELIKGFKKHQMHTALADIIESVEELRYYREHFIVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWP8</accession>
    <name>A0A2S9GWP8_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ammonium transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">S2091_3221</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the ammonia transporter channel (TC 1.A.11.2) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000016">
        <property type="protein sequence ID" value="PRC92086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92086">
        <property type="protein sequence ID" value="PRC92086"/>
        <property type="gene ID" value="S2091_3221"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008519">
        <property type="term" value="F:ammonium transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3430.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029020">
        <property type="entry name" value="Ammonium/urea_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001905">
        <property type="entry name" value="Ammonium_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018047">
        <property type="entry name" value="Ammonium_transpt_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024041">
        <property type="entry name" value="NH4_transpt_AmtB-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43029">
        <property type="entry name" value="PTHR43029"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00909">
        <property type="entry name" value="Ammonium_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00836">
        <property type="entry name" value="amt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01219">
        <property type="entry name" value="AMMONIUM_TRANSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0924">Ammonia transport</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="15"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="105"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="135"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="168"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="203"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="233"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="265"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="290"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="319"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="358"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="domain" description="Ammonium_transp" evidence="9">
        <location>
            <begin position="15"/>
            <end position="409"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC92086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="411" mass="44509" checksum="0744C50A41D273FF" modified="2018-07-18" version="1">MSQLIIPLNVGNTGFMLLCSSLVMLMTPGLAFFYGGLVGNKNVLSIMMQSFISLCWTTVLWFAFGYSMCFGPTINGIIGDPTYYAFLHGITLETMFKGNDAGIPLIVHVAYQMMFAIITPALITGAFANRVTFKAYFLFLTGWLVFVYFPFVHMVWSPDGLFAKWGVLDYAGGIVVHNTAGFAALASVLYVGRRQKVELKPHNVPLIALGSGLLWFGWYGFNAGSELRVDSVTASAFLNTDIAASFAAITWLLIEWYKHKKPKFVGLLTGGIAGLATITPAAGYVSLSSAALIGICAGAICFYAVALKNRFGWDDALDVWGVHGIGGMVGTILLGVFAAKAWNVNGADGLLLGNTSFFFMQVAAVIISGVWAFSFTYGMLWLINLFTPVRVDPASEDNMDDAFHGEEAYIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWX8</accession>
    <name>A0A2S9GWX8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3082</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92166">
        <property type="protein sequence ID" value="PRC92166"/>
        <property type="gene ID" value="S2091_3082"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="105" mass="11749" checksum="C28843D82B5CA64F" modified="2018-07-18" version="1">MTSTDQIHTQQHPPLITHLAVDTIDAYTQARDIVSDLSAIFEVLDHLALTDFSNKRITPILFRAGFCHATERLEFIEEKITDAYKTLDELKADNGHTAHTNSDAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWZ9</accession>
    <name>A0A2S9GWZ9_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Primosomal replication protein N</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">priB</name>
        <name evidence="2" type="ORF">S2091_3158</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Binds single-stranded DNA at the primosome assembly site (PAS).</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Component of the preprimosomal complex composed of PriA, PriB, PriC, DnaB and DnaT. Upon transient interaction with DnaG it forms the primosome.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the PriB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92242">
        <property type="protein sequence ID" value="PRC92242"/>
        <property type="gene ID" value="S2091_3158"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990077">
        <property type="term" value="C:primosome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006269">
        <property type="term" value="P:DNA replication, synthesis of RNA primer"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00720">
        <property type="entry name" value="PriB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023646">
        <property type="entry name" value="Prisomal_replication_PriB"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003135">
        <property type="entry name" value="Primosomal_n"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04418">
        <property type="entry name" value="PriB_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0235">DNA replication</keyword>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0639">Primosome</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00720"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="97" mass="10838" checksum="049C8612A7889CCB" modified="2018-07-18" version="1">MNQFQLVAQVVEREVLRYTPAGIPIVNATLAHSSQQLEANVVRLVEFEISALAVGEISGRFNQLELGCSHHFTGFMARKNRNSKSLVFHIVDIETTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXA3</accession>
    <name>A0A2S9GXA3_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">CTP synthase</fullName>
            <ecNumber evidence="9">6.3.4.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Cytidine 5'-triphosphate synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Cytidine triphosphate synthetase</fullName>
            <shortName evidence="9">CTP synthetase</shortName>
            <shortName evidence="9">CTPS</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">UTP--ammonia ligase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">pyrG</name>
        <name evidence="12" type="ORF">S2091_3011</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>ATP + H2O + L-glutamine + UTP = ADP + CTP + 2 H(+) + L-glutamate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:26426"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.2"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ATP + NH4(+) + UTP = ADP + CTP + 2 H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:16597"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>H2O + L-glutamine = L-glutamate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:15889"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </reaction>
    </comment>
    <comment type="activity regulation">
        <text evidence="9">Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 9">Pyrimidine metabolism; CTP biosynthesis via de novo pathway; CTP from UDP: step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homotetramer.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="9">CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the CTP synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.2" evidence="9"/>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92352">
        <property type="protein sequence ID" value="PRC92352"/>
        <property type="gene ID" value="S2091_3011"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00159">
        <property type="reaction ID" value="UER00277"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003883">
        <property type="term" value="F:CTP synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044210">
        <property type="term" value="P:'de novo' CTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03113">
        <property type="entry name" value="CTPS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01746">
        <property type="entry name" value="GATase1_CTP_Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01227">
        <property type="entry name" value="PyrG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004468">
        <property type="entry name" value="CTP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017456">
        <property type="entry name" value="CTP_synthase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033828">
        <property type="entry name" value="GATase1_CTP_Synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11550">
        <property type="entry name" value="PTHR11550"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06418">
        <property type="entry name" value="CTP_synth_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00337">
        <property type="entry name" value="PyrG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 9" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="4 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8 9" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CTP_synth_N" evidence="11">
        <location>
            <begin position="3"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="domain" description="GATase" evidence="10">
        <location>
            <begin position="300"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="region of interest" description="Amidoligase domain" evidence="9">
        <location>
            <begin position="1"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="L-glutamine binding" evidence="9">
        <location>
            <begin position="379"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile; for glutamine hydrolysis" evidence="9">
        <location>
            <position position="378"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="515"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="517"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="13"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="14"/>
            <end position="19"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="71"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="139"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="146"/>
            <end position="148"/>
        </location>
        <ligand>
            <name>CTP</name>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <note>allosteric inhibitor</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="186"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="222"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="240"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="351"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="402"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="468"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF06418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PRC92352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="543" mass="60559" checksum="C79572B4BFD612A8" modified="2018-07-18" version="1">MTKYVFVTGGVVSSLGKGIAAASLAAILESRGLKVTMLKLDPYINVDPGTMSPFQHGEVFVTDDGAETDLDLGHYERFITTRMKKVNNFTTGQIYESVIRKERRGEYLGKTVQVIPHITNEIQDYIRRGADGYDVALVEIGGTVGDIESLPFLEAARQLSLRSPKNTVAFVHLTLVPYLVSAGELKTKPTQHSVQKLREIGISPDALLCRADRPIPDDERAKISLFSNVHEEGVISLWDADTIYKVPQMLHDQGLDDLICERLGINPKPADLSMWTKLIHALENPKRDITIGMVGKYVDLTESYKSLTEALRHAGIHTESRVNIEYVDSEEIEKHGTKALEKFDGILVPGGFGKRGVEGKINAARYARENKVPYLGICLGMQVALIEYARNMADLKNANSTEFDADTDHPVVALINEWQNHDGKVQTRDENSDLGGTMRLGAQTCSVKPETLAAEIYGPKVTERHRHRYEANNHYLERVEQAGLIVSARTPTEDLCEIMELPRAVHPWYMGVQYHPEFKSTPRDGHPLFISFVKAILANKDSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXE1</accession>
    <name>A0A2S9GXE1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3042</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92383">
        <property type="protein sequence ID" value="PRC92383"/>
        <property type="gene ID" value="S2091_3042"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="96" mass="11265" checksum="62CD0D8B43FE849F" modified="2018-07-18" version="1">MMRDIEIIMNSFFKIFCHVQNENVIDGQPSECTEVSFQATPEIFRAVAAFLIECADKVEVQQICDVDHFHLQDQWKEWKSVYPDVIVFPVKNNLEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXI4</accession>
    <name>A0A2S9GXI4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NADPH:quinone reductase and related Zn-dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2807</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92432">
        <property type="protein sequence ID" value="PRC92432"/>
        <property type="gene ID" value="S2091_2807"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PKS_ER" evidence="1">
        <location>
            <begin position="10"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="326" mass="34544" checksum="4B34884CDE3CD655" modified="2018-07-18" version="1">MKAIVIKQYGGPEVLTVEERPIPEAKMGQILIEVKAFGVNHAEIYFRQGAWGDVAEISGIECVGVVKADPSGQFQVEQKVIAIVGGMGRSINGSYSEYTVVPASNVATVSTDLSWEELAAIPESYATAWSCLHGNLALKPDQTVLIRGATSALGQAAVNIAAHLGARVIATTRNAERAAGLEAIGAKEVLIEAPDLQDRVRERHPGGIDAVLDLIGNSTILDSLAMVCRDGRVCLAGFLGGGGPIANLEPVFQIPSGRHFSVFASALVIGSAEFPIMEIPFQDIVDRVAQGVYRAAPAHVFAFSEIREAHRLVESGQANGKIVIRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXI8</accession>
    <name>A0A2S9GXI8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2796</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92421">
        <property type="protein sequence ID" value="PRC92421"/>
        <property type="gene ID" value="S2091_2796"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="210" mass="23639" checksum="102F9F4745BE8B61" modified="2018-07-18" version="1">MNQESQILIARLITHQTLKREDKLVKRAITDELFRADVDARLLACGMKFVDNVYADHVTLALLRDVESKVFGARDSWQNNNFGLARDGVALLVVLWAMIILPKRERQASHQYGDVDQSEMFGKEKPMPRAAETSVGVSYKALLSDFGDKLGKKTKMDMNLGSLNRLGFIERKGDLICEGPLLDLMMDTDLLKERIVNGALADIFKLNPTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXN6</accession>
    <name>A0A2S9GXN6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2860</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92485">
        <property type="protein sequence ID" value="PRC92485"/>
        <property type="gene ID" value="S2091_2860"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="88" mass="10223" checksum="341D962D4FDE8530" modified="2018-07-18" version="1">MDQQRIKEAARRLKEVILKHSTTDGNMLFLLDRFLPIITDAVDGKFIEPTKIWGNKTIFDSGLYDQYQDLQDAYSTLSAELLDPNRFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXS7</accession>
    <name>A0A2S9GXS7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Methyltransferase small domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2885</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92510">
        <property type="protein sequence ID" value="PRC92510"/>
        <property type="gene ID" value="S2091_2885"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="234" mass="25933" checksum="98CC2AAB06002E9C" modified="2018-07-18" version="1">MDNISLLERTDLWQQERQEAIKALPRSGKAIQYLGKEFRVYPGTFLPFADSHPLVNNFHINPGESVLDVGTGSGVIAIFACYKGAGRVVAVDVNPSAIRSAKYNVRQHGFEHVVEVKQSCLFQQVGQDQFDVITANLPFRIKPAHDIVAQSQWDTDFKTNTGFFTEVGKYLKPNGRIYFSQANFGAIKEIKALAKAAGFSVHSLGSTVAKEVDKAGYAEFTVFLIKRMELESAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXV4</accession>
    <name>A0A2S9GXV4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2609</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92554">
        <property type="protein sequence ID" value="PRC92554"/>
        <property type="gene ID" value="S2091_2609"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="76" mass="8054" checksum="8BCC49963F194F2A" modified="2018-07-18" version="1">MRTTLAIDDDVLAAAKGLAVRQHKSVGEVISELVRQALQPVASAGVTRNGVPLLPLRSDAGVVTPELVNQLRDELN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXZ9</accession>
    <name>A0A2S9GXZ9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Molybdenum cofactor synthesis domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_2647</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; molybdopterin biosynthesis.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92592">
        <property type="protein sequence ID" value="PRC92592"/>
        <property type="gene ID" value="S2091_2647"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00344"/>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006777">
        <property type="term" value="P:Mo-molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00886">
        <property type="entry name" value="MogA_MoaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.980.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036425">
        <property type="entry name" value="MoaB/Mog-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001453">
        <property type="entry name" value="MoaB/Mog_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008284">
        <property type="entry name" value="MoCF_biosynth_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00994">
        <property type="entry name" value="MoCF_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00852">
        <property type="entry name" value="MoCF_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53218">
        <property type="entry name" value="SSF53218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00177">
        <property type="entry name" value="molyb_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01078">
        <property type="entry name" value="MOCF_BIOSYNTHESIS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0501">Molybdenum cofactor biosynthesis</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MoCF_biosynth" evidence="3">
        <location>
            <begin position="18"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC92592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="212" mass="23026" checksum="D4E81614254FDCE1" modified="2018-07-18" version="1">MSQIHIDPTQDSHQLRVGLISISDRASSGTYQDLGMPALQDWLAKCLLSPYQVVTRLIPDERAQIEQALVNLVDNHHCHLVLTTGGTGPSRRDVTPEATLAIASKEMPGFGEQMRQISLRFVPTALLSRQVAVIRETTDHAALIVNLPGQPKSIKETLEGLRDDAGNSVVPGIFAAIPYCIDLIGGPYIETDPAVCIAFRPKSAIKPTRSIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GY61</accession>
    <name>A0A2S9GY61_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2651</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92596">
        <property type="protein sequence ID" value="PRC92596"/>
        <property type="gene ID" value="S2091_2651"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="23"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="71"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="127" mass="14564" checksum="8E9F150909CD5ABE" modified="2018-07-18" version="1">MSQNTSQELVFDSKLESIKNFAWWFYIFHAVSMLFTLGALSFIPVILSYVKRGEAAGTFVYSHHNWQISSFWIYLACVFIGWMLFITIIGIPVAVILWGCAWLWKAYRLIVGIMALNDNQAIGESTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYD6</accession>
    <name>A0A2S9GYD6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2448</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92718">
        <property type="protein sequence ID" value="PRC92718"/>
        <property type="gene ID" value="S2091_2448"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015667007" evidence="1">
        <location>
            <begin position="31"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="191" mass="20381" checksum="A7A8C4A970B90DF6" modified="2018-07-18" version="1">MNISSKNYPNMFGSLSCALLCLLVASLLHAEPAQTVRNTDLQAQSQSDAQVLAALPINTRLDVLLRRGAWSQVKTNAGQTGWVRMLSLRFDTSGSAADTGSSSNPLSALTSLFSTGRTSNTGTVTTGVKGLGEEDLKNAQENPGEMHKMQKLAVDKKTAKDFAQRSKLTPNHVAYLSTDTKHADNSRSGGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYQ1</accession>
    <name>A0A2S9GYQ1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">EamA-like transporter family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2587</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92857">
        <property type="protein sequence ID" value="PRC92857"/>
        <property type="gene ID" value="S2091_2587"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="65"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="92"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="119"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="162"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="187"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="226"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="278"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="5"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="159"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="296" mass="32306" checksum="86FD4BDAC86BB329" modified="2018-07-18" version="1">MSHFAFFLVILAGFIHAMWNIAAKKAGGDARFACLSNLILMVVWAPVGIYFGWDVVPDWGWKEWSFIVASGVLHGLYFVTLLRGYRKSELTVVYPMARGFAPLISSFAALFLLGEQISLFGVLGILAVVGGVFLIAGGPKIFRAVLAGSGAESQRKRIHKGIYYGLLTGIFIAAYTVLDGYAVKVLLLAPVLLYYFCNFFQVAFLLPALWRNQYSTIVSWRSQWKYALIVAVVSPISYVLVLYAMQIAPLSHVAPAREVSMLFAALIGGRLLGEGDRVIRIVGAVFIAGGVIALGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYQ4</accession>
    <name>A0A2S9GYQ4_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Iron-sulfur cluster carrier protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_2585</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the Mrp/NBP35 ATP-binding proteins family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">In the N-terminal section; belongs to the MIP18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92855">
        <property type="protein sequence ID" value="PRC92855"/>
        <property type="gene ID" value="S2091_2585"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140663">
        <property type="term" value="F:ATP-dependent FeS chaperone activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02040">
        <property type="entry name" value="Mrp_NBP35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034904">
        <property type="entry name" value="FSCA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002744">
        <property type="entry name" value="MIP18-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019591">
        <property type="entry name" value="Mrp/NBP35_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000808">
        <property type="entry name" value="Mrp_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044304">
        <property type="entry name" value="NUBPL-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033756">
        <property type="entry name" value="YlxH/NBP35"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42961">
        <property type="entry name" value="PTHR42961"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01883">
        <property type="entry name" value="FeS_assembly_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10609">
        <property type="entry name" value="ParA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117916">
        <property type="entry name" value="SSF117916"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01215">
        <property type="entry name" value="MRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FeS_assembly_P" evidence="6">
        <location>
            <begin position="7"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="106"/>
            <end position="113"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC92855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="362" mass="38353" checksum="3C510F546FA8C1FD" modified="2018-07-18" version="1">MSVTENHIKSALSLVIDPNTNKDLISSKSVKNIQLHGSDVSLDVELGYPASSQFDLIRANVAEAILALDGVAAVNVNVSSKIVAHSVQRGIKLMSNVKNIIAVASGKGGVGKSTTAVNLALALSAEGARVGILDADIYGPSLPMMMGIEGRPESLDGKTMEPLENHGIQVSSIGFMIDPAEPMVWRGPMVTQALVQLLEQTNWRELDYLIIDMPPGTGDVQLTLSQKVPVTGAVIVTTPQDIALLDARKGLKMFEKVGIPILGIVENMSTHICSNCGHQEAIFGAGGGEKMCAEYGVELLASMPLTMTIREQADSGRPTVVADPTGVVTALYKEIARKVAIKVAEKAKDMSSKFPTITVQNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZA0</accession>
    <name>A0A2S9GZA0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Phage integrase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_2148</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93062">
        <property type="protein sequence ID" value="PRC93062"/>
        <property type="gene ID" value="S2091_2148"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0075713">
        <property type="term" value="P:establishment of integrated proviral latency"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046718">
        <property type="term" value="P:viral entry into host cell"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044826">
        <property type="term" value="P:viral genome integration into host DNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.390">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044068">
        <property type="entry name" value="CB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002104">
        <property type="entry name" value="Integrase_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038488">
        <property type="entry name" value="Integrase_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025166">
        <property type="entry name" value="Integrase_DNA_bind_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010998">
        <property type="entry name" value="Integrase_recombinase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13356">
        <property type="entry name" value="Arm-DNA-bind_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00589">
        <property type="entry name" value="Phage_integrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51900">
        <property type="entry name" value="CB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51898">
        <property type="entry name" value="TYR_RECOMBINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0229">DNA integration</keyword>
    <keyword evidence="3" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="2 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-1179">Viral genome integration</keyword>
    <keyword evidence="5" id="KW-1160">Virus entry into host cell</keyword>
    <feature type="domain" description="Core-binding (CB)" evidence="8">
        <location>
            <begin position="97"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="domain" description="Tyr recombinase" evidence="7">
        <location>
            <begin position="199"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC93062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="407" mass="46407" checksum="2B03F6CFCA677539" modified="2018-07-18" version="1">MLTDTKLRNLKPQGKLYKVNDRDGLYVAVTPAGSISFRYNYSINGRQETLTFGRYGAGGITLSEAREQLNDAKKLISTGKSPAKEKARGKARIKDLETFGAWADKWLRGYQMADSTRDMRKSIYERELKPKFANQKLAEFTHEDLRALTDSIVERGAPATAVHVREVVMQVFRWAIERGQKVENPADMVRPTTIAKFEPRDRALTPEEIGLMYQYMERIGTTPSIRAAAKLLLLTLVRKSELTNATWSEINFTDAVWTVPKERMKRRNPHHVYLSQQALDIFIALKTFAGGSEYILPSRYDSDLPMSSATLNQVLSLTYKLAQKEGKALPKFGPHDLRRTGSTLLHEAGYNTDWIEKCLAHEQRGVRAVYNKAEYREQRTAMLQDWANMIDEWTIKRKQPSALSLVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZG1</accession>
    <name>A0A2S9GZG1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2176</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93090">
        <property type="protein sequence ID" value="PRC93090"/>
        <property type="gene ID" value="S2091_2176"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015522265" evidence="1">
        <location>
            <begin position="22"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="310" mass="32362" checksum="8D1FD96B07389259" modified="2018-07-18" version="1">MKVLKVIFATALACTATLSFANTPRPSIQGNTPAEIQARFSNIIEQNFINGKADQIIENLSSQEMADLAAFYGDAKQGDTSALLQILASKLNAQHLVKVGRAFGNELTYSAVAKYASKDVRDEFNVTPKGSVLPINFYANLAIANAHSIPRVSAPTATLVGGIATPMVGPAPTADMSLYDIYLEFRTATIGSLSVESALYESAAFAGSRLIVAYGVGYAVGTQVNSLINTYDPALGSAIGSAVATVVNTVTNFGQTTPTTAAGAQAQTQMDSLMGSILPLTSPGDYNVTQDMAEMNSVGGSICTYGCKLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZP3</accession>
    <name>A0A2S9GZP3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2172</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93086">
        <property type="protein sequence ID" value="PRC93086"/>
        <property type="gene ID" value="S2091_2172"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021508">
        <property type="entry name" value="Gp17-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11367">
        <property type="entry name" value="DUF3168"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="119" mass="13372" checksum="557437A8C24DE427" modified="2018-07-18" version="1">MSVESHITNALNPLVDQRVYPDIAPEQTKPPYITYQQVGGASVNFLNGAIPTKRNSRFQINVWAKTRDEAAKLSKRADKALRQAQELQTTVLGEAIAVIDQETKLRGTRQDFSFWVNVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZW0</accession>
    <name>A0A2S9GZW0_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 10">Glutamyl-tRNA(Gln) amidotransferase subunit A</fullName>
            <shortName evidence="10">Glu-ADT subunit A</shortName>
            <ecNumber evidence="4 10">6.3.5.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">gatA</name>
        <name evidence="12" type="ORF">S2091_2010</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>ATP + H2O + L-glutamine + L-glutamyl-tRNA(Gln) = ADP + H(+) + L-glutamate + L-glutaminyl-tRNA(Gln) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:17521"/>
            <dbReference type="Rhea" id="RHEA-COMP:9681"/>
            <dbReference type="Rhea" id="RHEA-COMP:9684"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:78520"/>
            <dbReference type="ChEBI" id="CHEBI:78521"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.5.7"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="3 10">Heterotrimer of A, B and C subunits.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the amidase family. GatA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.7" evidence="4 10"/>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93272">
        <property type="protein sequence ID" value="PRC93272"/>
        <property type="gene ID" value="S2091_2010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030956">
        <property type="term" value="C:glutamyl-tRNA(Gln) amidotransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050567">
        <property type="term" value="F:glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00120">
        <property type="entry name" value="GatA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000120">
        <property type="entry name" value="Amidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020556">
        <property type="entry name" value="Amidase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023631">
        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004412">
        <property type="entry name" value="GatA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11895">
        <property type="entry name" value="PTHR11895"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01425">
        <property type="entry name" value="Amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="SSF75304"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00132">
        <property type="entry name" value="gatA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00571">
        <property type="entry name" value="AMIDASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="7 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9 10" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Amidase" evidence="11">
        <location>
            <begin position="22"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="10">
        <location>
            <position position="74"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="10">
        <location>
            <position position="149"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-ester intermediate" evidence="10">
        <location>
            <position position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00014428"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PRC93272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="485" mass="51944" checksum="A85933227DB90975" modified="2018-07-18" version="1">MHTKTLTEISALLHSKQLSATELAQHYLNRIAASDLNAFTHVDPALTLAQAAHADKLLAQPNPHALAGIPIAHKDIFVTRGWRSTAGSKMLANYTSPFDATVVEQFNQAGMVTLGKLNCDEFAMGSANENSFFGAVKNPWDKRAVPGGSSGGSAAAIAARLAPAATATDTGGSIRQPASFCGVTGIKPTYGRVSRFGMIAFASSLDQGGPIAQTAEDCALLLNSMAGFDARDSTSLEHPNEDFRRDLNTPLKGLRIGVPREFFGAGLATDVEQAVRAALAKYEDLGAILVDISLPKTELSIPVYYVIAPAEASSNLSRFDGVRYGHRAANYDGLTDMYKKSRTEGFGDEVKRRILVGSYVLSHGYYDAYYLQAQKIRRLIAEDFQAAFKQCDVIMGPVAPTVAWDLGDKADDPVANYLADIFTLSTSLAGLPGMSLPCGFGQGEKNSKRPVGLQLIGNYFSEAKLLGVAHQYQLATAWHTQTPSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H036</accession>
    <name>A0A2S9H036_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Acyl-CoA dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">S2091_2083</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93345">
        <property type="protein sequence ID" value="PRC93345"/>
        <property type="gene ID" value="S2091_2083"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003995">
        <property type="term" value="F:acyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901565">
        <property type="term" value="P:organonitrogen compound catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd01156">
        <property type="entry name" value="IVD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006089">
        <property type="entry name" value="Acyl-CoA_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034183">
        <property type="entry name" value="IVD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="SSF47203"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="SSF56645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00072">
        <property type="entry name" value="ACYL_COA_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00073">
        <property type="entry name" value="ACYL_COA_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA_dh_N" evidence="10">
        <location>
            <begin position="15"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_M" evidence="9">
        <location>
            <begin position="128"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_1" evidence="8">
        <location>
            <begin position="235"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="6">
        <location>
            <begin position="246"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="6">
        <location>
            <begin position="375"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="248"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="129"/>
            <end position="138"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="138"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="162"/>
            <end position="164"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="274"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="285"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="348"/>
            <end position="352"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="377"/>
            <end position="379"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR634183-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR634183-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR634183-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC93345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="394" mass="42885" checksum="851AECBB29F7865B" modified="2018-07-18" version="1">MLHLPGLTFDHGEDIAALRESVQQFASKEIAPRAAEIDKTDQFPMDLWKKMGDLGVLGVTVKEEDGGIEMGYLAHIIAMEEISRASASVGLSYGAHSNLCVNQINRNGTPEQKAKYLPKLISGEHIGALAMSEPNAGSDVVSMKLRADWKGDRWVLNGTKMWITNGPDADVLVVYAKNDLEAGPRGMTAFLIEKNFPGFSIAQKLDKLGMRGSHTGELVFQDCEVPAENVLGGLGKGVNVLMSGLDFERTVLSGGPLGIMQACMDVVVPYIHDRKQFGQPIGEFQLMQGKIADMYSTMMACKAYVYAVGQACDRAKNPEAVRALRKDAAGAILYSAEKATWMAGEAIQILGGNGYINEYSVGRLWRDAKLYEIGAGTSEIRRMLIGRELFAETK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H037</accession>
    <name>A0A2S9H037_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2051</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93313">
        <property type="protein sequence ID" value="PRC93313"/>
        <property type="gene ID" value="S2091_2051"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014991">
        <property type="entry name" value="DUF1840"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08895">
        <property type="entry name" value="DUF1840"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="115" mass="12825" checksum="A6160F1226707E23" modified="2018-07-18" version="1">MLITFKCKASPDIVMYKEHAQRILELLDKDVERGIIMHTDTTTAIATIEAAIADSRAHSVTEFVQHDITAHPQPSENGDHVHERVENVSFASRAFPFLQMLRAANAQGSEIVWGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H098</accession>
    <name>A0A2S9H098_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Aldose 1-epimerase</fullName>
            <ecNumber evidence="3">5.1.3.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_1788</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>alpha-D-glucose = beta-D-glucose</text>
            <dbReference type="Rhea" id="RHEA:10264"/>
            <dbReference type="ChEBI" id="CHEBI:15903"/>
            <dbReference type="ChEBI" id="CHEBI:17925"/>
            <dbReference type="EC" id="5.1.3.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 3">Carbohydrate metabolism; hexose metabolism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the aldose epimerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.1.3.3" evidence="3"/>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93401">
        <property type="protein sequence ID" value="PRC93401"/>
        <property type="gene ID" value="S2091_1788"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00242"/>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004034">
        <property type="term" value="F:aldose 1-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019318">
        <property type="term" value="P:hexose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015443">
        <property type="entry name" value="Aldose_1-epimerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008183">
        <property type="entry name" value="Aldose_1/G6P_1-epimerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014718">
        <property type="entry name" value="GH-type_carb-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01263">
        <property type="entry name" value="Aldose_epim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005096">
        <property type="entry name" value="GALM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="SSF74650"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="6">
        <location>
            <begin position="53"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="6">
        <location>
            <begin position="149"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="4">
        <location>
            <position position="149"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="287"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="219"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR005096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR005096-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR005096-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR005096-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC93401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="321" mass="35600" checksum="7D0ECE3ADE0532EA" modified="2018-07-18" version="1">MTVTVSPHGASLVSWLAPDRDGQLADVLLGYRNATDYVNNFDYFGAIVGRWANRISTAHFTLDGVQYHVDSNDGIHHLHGGYAGLHRVFWQVTQSQNELILQYLDPDGSGGFPGNLRIVLRYRLDELGQLSIVYEAHTDRATPVNLTSHPYFNLNGGLTDIGEHLLTINASYYLQTDADHIPIQCADVSGSAFDFRQPAAIGPRLSWLDAQPPVQSIFDHCYCVQPERDGRSGKLRQVAAVFDPASGRNLSVCTDQAGLQFYSGNFLTGVSGRGNSVYERYAGFCLEAQAYPNQINSPWADAVVLRPGQIYRQTTIYRVWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0A1</accession>
    <name>A0A2S9H0A1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Pro-kumamolisin, activation domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_1799</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93412">
        <property type="protein sequence ID" value="PRC93412"/>
        <property type="gene ID" value="S2091_1799"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04056">
        <property type="entry name" value="Peptidases_S53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11377">
        <property type="entry name" value="Pro-peptidase_S53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015366">
        <property type="entry name" value="S53_propep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030400">
        <property type="entry name" value="Sedolisin_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09286">
        <property type="entry name" value="Pro-kuma_activ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00944">
        <property type="entry name" value="Pro-kuma_activ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="SSF52743"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51695">
        <property type="entry name" value="SEDOLISIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0106">Calcium</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0720">Serine protease</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015754275" evidence="5">
        <location>
            <begin position="29"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S53" evidence="6">
        <location>
            <begin position="214"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="4">
        <location>
            <position position="286"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="4">
        <location>
            <position position="290"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="4">
        <location>
            <position position="544"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC93412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="627" mass="66769" checksum="C058F818D24A093B" modified="2018-07-18" version="1">MKLKTKPLAAAVSGLFIGALCLPGSAFAAKSLTTAQDTGAISPTQTQTVSIVLQLRNANELNKYINDTVDPNSPNYHHFLSVDEFAHRYAPTDADVNRVKADLGKLGIQVSEVYRSHMVIRATGSTAQFNKYLATEVHSYKENGLSYIKPSVALTIPSSVSDVVMAVIGLNTKPKLHSLSHNLAKDSGGTMKMVPGTKGIKLANGVTTTNSPGSFTVTDVAELYNINPLYQQGILGQNHNIGIATFATFTASDAYTYWQTIGLHVASDRITEIPVDGGTGTNGSGETTLDVEQSGGVAPAAKVYVYEAPNTDQGFADVFLKAAADNTVDTLSMSWGGTEFGQDTGVMPAVHQALMELAAQGISVLTSSGDEGAYDINNNQGYYYYPGCTATLSVEYPASDSMILAAGGITLAGTQTFYNSNNVVVGSVTVPKDRAWAWDYLQNFFITNFGDNSYYEHLFPVGGGGGVSVEFDLPYYQQNLHGTQVTAANQALICQTSTGPVDLIDLPDGYAGRNVPDISLNADPDTGYAEYVGGQWAYYWGGTSFVAPQLNGMAILVSQVSGTRLGFLNPQLYSRFNQFGYGSNSPFRAVTAGDNEYYQSTYGYSPATGIGAIDVTKLAKSFSRGGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0B7</accession>
    <name>A0A2S9H0B7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional activator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1808</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93421">
        <property type="protein sequence ID" value="PRC93421"/>
        <property type="gene ID" value="S2091_1808"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025979">
        <property type="entry name" value="ChrR-like_cupin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12973">
        <property type="entry name" value="Cupin_7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cupin_7" evidence="1">
        <location>
            <begin position="19"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="domain" description="Cupin_7" evidence="1">
        <location>
            <begin position="127"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="219" mass="24255" checksum="DD06ACCE3688EF50" modified="2018-07-18" version="1">MKLNADQSKRVVLYSEQLPWVASPVPGIERRLLARDGAEQAKATSIVRYEAGAVFTPHAHPQGEEVVVLEGMFEDEHGSYPTGTYIKNPPGSVHTPKSTDGCVLFVKLRHLDDDDLERVVVRPANQQWHPGMVKGLKVAALDQFGTSHTALVRWAPGTYFSKHQHYGGEEILVLEGTFQDEYGSYPTGTWIRSPHLSAHQPYSESGCLILVKVGHLMDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0H8</accession>
    <name>A0A2S9H0H8_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Cytochrome-c oxidase</fullName>
            <ecNumber evidence="5">7.1.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">S2091_1868</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>4 Fe(II)-[cytochrome c] + 8 H(+)(in) + O2 = 4 Fe(III)-[cytochrome c] + 4 H(+)(out) + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:11436"/>
            <dbReference type="Rhea" id="RHEA-COMP:10350"/>
            <dbReference type="Rhea" id="RHEA-COMP:14399"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="EC" id="7.1.1.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Cu(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29036"/>
        </cofactor>
        <text evidence="10">Binds 1 copper ion per subunit, denoted as copper B.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
        <text evidence="10">Binds 2 heme groups per subunit, denoted as high- and low-spin.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Energy metabolism; oxidative phosphorylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 11">Belongs to the heme-copper respiratory oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.1.1.9" evidence="5"/>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93481">
        <property type="protein sequence ID" value="PRC93481"/>
        <property type="gene ID" value="S2091_1868"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00705"/>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045278">
        <property type="term" value="C:plasma membrane respiratory chain complex IV"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004129">
        <property type="term" value="F:cytochrome-c oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006119">
        <property type="term" value="P:oxidative phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01661">
        <property type="entry name" value="cbb3_Oxidase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.210.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023616">
        <property type="entry name" value="Cyt_c_oxase-like_su1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036927">
        <property type="entry name" value="Cyt_c_oxase-like_su1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000883">
        <property type="entry name" value="Cyt_C_Oxase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023615">
        <property type="entry name" value="Cyt_c_Oxase_su1_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004677">
        <property type="entry name" value="Cyt_c_oxidase_cbb3_su1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10422">
        <property type="entry name" value="PTHR10422"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10422:SF29">
        <property type="entry name" value="PTHR10422:SF29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00115">
        <property type="entry name" value="COX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81442">
        <property type="entry name" value="SSF81442"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00780">
        <property type="entry name" value="ccoN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50855">
        <property type="entry name" value="COX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00077">
        <property type="entry name" value="COX1_CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0249">Electron transport</keyword>
    <keyword evidence="10 11" id="KW-0349">Heme</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="8 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="6 11 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="11" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="59"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="91"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="126"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="160"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="202"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="233"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="272"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="304"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="340"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="383"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="429"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="domain" description="COX1" evidence="13">
        <location>
            <begin position="15"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="205"/>
        </location>
        <ligand>
            <name>Cu cation</name>
            <dbReference type="ChEBI" id="CHEBI:23378"/>
            <label>B</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="255"/>
        </location>
        <ligand>
            <name>Cu cation</name>
            <dbReference type="ChEBI" id="CHEBI:23378"/>
            <label>B</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="256"/>
        </location>
        <ligand>
            <name>Cu cation</name>
            <dbReference type="ChEBI" id="CHEBI:23378"/>
            <label>B</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00029368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR604677-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="PRC93481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="479" mass="54103" checksum="528F2BB3514DBEDD" modified="2018-07-18" version="1">MDKELNYNYKIVKQFTIATVVWGVVGMLVGVIIAAQLAWPALNFDIPWLTYGRLRPLHTNAVIFAFGICGLFATSYYVVQRTCQVRLYSDKLAAFTFWGWQLVIIAAAITLPMGYTRGKEYAELEWPITILIAVVWIAYAVVFFGTLIKRKVKHIYVANWFFAAYIIAVTLLHVVNGASMPASMWKSYSAYSGVQDAMIQWWYGHNAVGFILTAGYLGMVYYFIPKQAERPVYSYRLSIVHFWALIFTYMWAGPHHLHYTALPDWTQSLGMVFSLILLAPSWGGMINGIMTLSGAWHKLRSDPILKFMIVSLSFYGMATFEGPMMSIKTVNSLSHYTDWGIAHVHSGALGWVGFITMGSIYYLIPRVVGKKEMWSTRLIDIHFWVATIGVVLYISSMWIAGVMQGLMWRAVNPDGTLTYTFVEGVKATYPYYVIRVCGGALYLSGMLTMAYNTFMTMRDSKEVQARIPSLITGTTSAHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0M7</accession>
    <name>A0A2S9H0M7_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Malate dehydrogenase</fullName>
            <ecNumber evidence="3">1.1.1.37</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">mdh</name>
        <name evidence="9" type="ORF">S2091_1803</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the reversible oxidation of malate to oxaloacetate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>(S)-malate + NAD(+) = H(+) + NADH + oxaloacetate</text>
            <dbReference type="Rhea" id="RHEA:21432"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15589"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.37"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the LDH/MDH superfamily. MDH type 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.37" evidence="3"/>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93416">
        <property type="protein sequence ID" value="PRC93416"/>
        <property type="gene ID" value="S2091_1803"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030060">
        <property type="term" value="F:L-malate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006108">
        <property type="term" value="P:malate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01517">
        <property type="entry name" value="Malate_dehydrog_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001557">
        <property type="entry name" value="L-lactate/malate_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022383">
        <property type="entry name" value="Lactate/malate_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001236">
        <property type="entry name" value="Lactate/malate_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015955">
        <property type="entry name" value="Lactate_DH/Glyco_Ohase_4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010945">
        <property type="entry name" value="Malate_DH_type2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23382">
        <property type="entry name" value="PTHR23382"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02866">
        <property type="entry name" value="Ldh_1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00056">
        <property type="entry name" value="Ldh_1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000102">
        <property type="entry name" value="Lac_mal_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56327">
        <property type="entry name" value="SSF56327"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01759">
        <property type="entry name" value="MalateDH-SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0520">NAD</keyword>
    <keyword evidence="2 3 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="Ldh_1_N" evidence="7">
        <location>
            <begin position="7"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="domain" description="Ldh_1_C" evidence="8">
        <location>
            <begin position="158"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3 4">
        <location>
            <position position="188"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="12"/>
            <end position="18"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="93"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3 5">
        <location>
            <position position="99"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="106"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="113"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="130"/>
            <end position="132"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3 5">
        <location>
            <position position="132"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3 5">
        <location>
            <position position="163"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000102-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000102-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC93416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="326" mass="35454" checksum="79C47CFAD5AC7B8D" modified="2018-07-18" version="1">MEKKPIRIAVTGAAGQIGYALLFRIAKGDITGTNQPIILQLLEIPSSQQALKGVVMELEDCAFPLLSDIIVTDDPSVAFQDANMVIMVGARPRSKGMERKDLLLANAEIFKIQGSALNQCVARDAKILVVGNPANTNALIAMTSAPDLDRNNFSAMIRLDHNRALSILAKKIGSPISQISQLIVWGNHSPTMYADYRFALNSDQPLAYNLQDENWNTEVFIPTVAQRGTAIIEARGVSSAASAANAIIDHMRDWVMGSNGRWVSMALPSDGSYGVPEGIFFGVPAICENGVIKRVANLEINEFSKRKLQSSVDELMGERKLILSML</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0N0</accession>
    <name>A0A2S9H0N0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative glycosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_1543</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93542">
        <property type="protein sequence ID" value="PRC93542"/>
        <property type="gene ID" value="S2091_1543"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="263"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_trans_2-like" evidence="3">
        <location>
            <begin position="9"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC93542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="303" mass="34365" checksum="25654566416B0D44" modified="2018-07-18" version="1">MEIMNFDISTVIVNYNAGDLLYACVNSLLNCPLKIEIIIVDNASSDQSLNALVGLPNVHLIKNVTNLGFAAACNQGTNKATAPILLFLNPDCSFKPGALVSLLETMCKDAEVGMVGGLLVNWDGTEQAGGRRAIPTPWRSFVRAFGLVRFSGRWPKLFYDFHLHKQKLPDHPIEVEAISGACMMVRRDVMQDVGGWDEGYFLHCEDLDWCMRFRQKGWKILFVPTAKITHALGACGKNKKVFVEWHKHKGMIRFYHKFFRHQYPGALMALIVVGVWLRFGMVATHHSTQHFRNALRSKRRRYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0Z0</accession>
    <name>A0A2S9H0Z0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Gram-negative porin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_1653</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93652">
        <property type="protein sequence ID" value="PRC93652"/>
        <property type="gene ID" value="S2091_1653"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046930">
        <property type="term" value="C:pore complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015288">
        <property type="term" value="F:porin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006811">
        <property type="term" value="P:ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00342">
        <property type="entry name" value="gram_neg_porins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033900">
        <property type="entry name" value="Gram_neg_porin_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023614">
        <property type="entry name" value="Porin_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002299">
        <property type="entry name" value="Porin_Neis"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13609">
        <property type="entry name" value="Porin_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00184">
        <property type="entry name" value="NEISSPPORIN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0406">Ion transport</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0626">Porin</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1134">Transmembrane beta strand</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015485990" evidence="5">
        <location>
            <begin position="21"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="domain" description="Porin_4" evidence="6">
        <location>
            <begin position="7"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF13609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC93652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="361" mass="37528" checksum="163B0BF151D8AE4E" modified="2018-07-18" version="1">MKKSLLAIAVLASFAGAASAQSSVTVFGTLDAGMTYANTGTQAPLNTANDKWSMDSGVSQASFIGFKGVEDLGGNLKAIFQLEAGIQIDNGTSSQANTLFNRASWVGLSGDFGTVTAGRQFTPLYEAVKTIDPFQLGMAGSASNLMSTGGASIVNGAIVAGNSVTNVAQNNSLRYASQSVSGLSAIVNYSFGEQAGNTNAGRDIGATVNYANGPLSLLVSYDGVKTLDDTTTLQTTLLGGVADWAQFGFPLKTSIGYAINKGSDVVGVADVDSRDLIIGLRLPMAQHEVLASFVHKDDKTTADLNAEQFALGYTYAISKRTVLYTSVSKMINKNGAAYTVGNASNTGYGVKVFDFGIRHSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H182</accession>
    <name>A0A2S9H182_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="8">GGDEF: diguanylate cyclase (GGDEF) domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_1740</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93739">
        <property type="protein sequence ID" value="PRC93739"/>
        <property type="gene ID" value="S2091_1740"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033479">
        <property type="entry name" value="dCache_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02743">
        <property type="entry name" value="dCache_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="288"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="7">
        <location>
            <begin position="352"/>
            <end position="484"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC93739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="487" mass="54859" checksum="E6734FF4E19C0411" modified="2018-07-18" version="1">MRHLYKKYRLLVWLGLLLIIGIVANSAVTLYSTRALMVQTSAQKTLPLTGDSLSAEIQRNIARSILTSARMADDAVVRDWILSDEHDSARLLAHLKSAQQKDQSTSHFLVTEKDRQFYDSQGVIRTINPENFHDTWYFKTRAAKHAYETTVAAESDETNHPNLYISYRIQNSEGKFLGAAGVSMPLELVTKAMDHYVNDFKRSVYFVDTSGKIVLSDNQHNLHGNIHEQEGIKQIAEEILNNEHTELNSSYELAATNILFNARYIPELGWHLIVESDAADEAAQVQPLFFVNAAIGVIITTLALLLAWFSIAHHQSRLLALTNCDGMTGLMNRQSFTTSFQQTVLDMRRAKYPLSFILFDIDFLKKINELHGHVTGDQIIMDIARMSKESVRGSDLLCRWGGEQFALLLKKCELEQAYKVAEQLRLNVQNHAFSIADGAASVTISLGVAEWAENESADELFARVDEAMYFAKSEGRNRAEVSYYVSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H185</accession>
    <name>A0A2S9H185_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ABC-type hemin transport system periplasmic component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1627</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93626">
        <property type="protein sequence ID" value="PRC93626"/>
        <property type="gene ID" value="S2091_1627"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002491">
        <property type="entry name" value="ABC_transptr_periplasmic_BD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01497">
        <property type="entry name" value="Peripla_BP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50983">
        <property type="entry name" value="FE_B12_PBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe/B12 periplasmic-binding" evidence="1">
        <location>
            <begin position="12"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="262" mass="27718" checksum="8A37321A0368CA31" modified="2018-07-18" version="1">MLALLPSAHAARVISIGGSMTEIVYLLGAEKELVAVDSTSQFPAAASKLPQIGYQRSLSTEGILALRPDLVLATADAGPPVVLKQLQQVGVKLNQAQVQHTAENVLEKIRLISHALNLPSTSLEQQFQRQWQSTKTKVAEYGSHPKVLFILDHSGTSSMIAGDQTAAQAMIDYAGGSNAVRGVTGYKPLTAEAVIMAAPAVILISQEGLDAIGGVDKLLQRPGLSMTPAGKTRRIVVMDAAYLLGFGPRLPQAVLDLATKIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1A3</accession>
    <name>A0A2S9H1A3_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribosomal RNA small subunit methyltransferase A</fullName>
            <ecNumber evidence="6">2.1.1.182</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">16S rRNA dimethyladenosine transferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">16S rRNA dimethylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rsmA</name>
        <name evidence="6" type="synonym">ksgA</name>
        <name evidence="9" type="ORF">S2091_1368</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>adenosine(1518)/adenosine(1519) in 16S rRNA + 4 S-adenosyl-L-methionine = 4 H(+) + N(6)-dimethyladenosine(1518)/N(6)-dimethyladenosine(1519) in 16S rRNA + 4 S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:19609"/>
            <dbReference type="Rhea" id="RHEA-COMP:10232"/>
            <dbReference type="Rhea" id="RHEA-COMP:10233"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74493"/>
            <dbReference type="EC" id="2.1.1.182"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.182" evidence="6"/>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93759">
        <property type="protein sequence ID" value="PRC93759"/>
        <property type="gene ID" value="S2091_1368"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052908">
        <property type="term" value="F:16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00607">
        <property type="entry name" value="16SrRNA_methyltr_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001737">
        <property type="entry name" value="KsgA/Erm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023165">
        <property type="entry name" value="rRNA_Ade_diMease-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020596">
        <property type="entry name" value="rRNA_Ade_Mease_Trfase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020598">
        <property type="entry name" value="rRNA_Ade_methylase_Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011530">
        <property type="entry name" value="rRNA_adenine_dimethylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11727">
        <property type="entry name" value="PTHR11727"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00398">
        <property type="entry name" value="RrnaAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00650">
        <property type="entry name" value="rADc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00755">
        <property type="entry name" value="ksgA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01131">
        <property type="entry name" value="RRNA_A_DIMETH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51689">
        <property type="entry name" value="SAM_RNA_A_N6_MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 6 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="1 6" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="4 6 7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 6 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="rADc" evidence="8">
        <location>
            <begin position="19"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="12"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="14"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="39"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="60"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="84"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="106"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC93759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="258" mass="28868" checksum="01B7E93D560B5189" modified="2018-07-18" version="1">MKHIPRKRFGQNFLTDVSVLNEIIRTIDPQPNDSMVEIGPGLAAMTRLLLKGVSFLHVVELDRDLVTRLQKEFDPAKLQVHAGDALKFDFSKIPVAEGQKLRVVGNLPYNISSPLLFHLAEIAPLVQDQHFMLQKEVVERMVAEPGSKAFGRLSVMLQWRYHMQLMFIVPPTAFDPPPKVDSAIVRMIPKTAPLACDIKHLQTTVTKAFSQRRKVIKNCVAGMFTEAQLLQAGIDPTLRPEAVGLEQYVALANLLKSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1E0</accession>
    <name>A0A2S9H1E0_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">GBBH-like_N domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_1410</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93801">
        <property type="protein sequence ID" value="PRC93801"/>
        <property type="gene ID" value="S2091_1410"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2020.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010376">
        <property type="entry name" value="GBBH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038492">
        <property type="entry name" value="GBBH-like_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06155">
        <property type="entry name" value="GBBH-like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GBBH-like_N" evidence="3">
        <location>
            <begin position="7"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF06155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC93801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="132" mass="14672" checksum="C06DC32608D1CCDF" modified="2018-07-18" version="1">MNPTAINVRMQSRLVEIEFDDVKFALSFELMRVYSPSAEVRGHGAGQEILQTGKRDVSLTALEPVGHYAVQPHFTDGHNTGIFSWEYLHWLGENQSRLWQEYLDKLQAAGFSGDSGRDAPMEVAGKGCSTKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1H2</accession>
    <name>A0A2S9H1H2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_1443</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93834">
        <property type="protein sequence ID" value="PRC93834"/>
        <property type="gene ID" value="S2091_1443"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010559">
        <property type="entry name" value="Sig_transdc_His_kin_internal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06580">
        <property type="entry name" value="His_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="36"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="61"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="101"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="135"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="domain" description="His_kinase" evidence="3">
        <location>
            <begin position="183"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF06580"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC93834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="375" mass="42213" checksum="A7C14EB403C1D86D" modified="2018-07-18" version="1">MKLTSLNVPGYPGTHPQTAANSGGTSSGSTALRYGLCQLLGWGLIVLFNLSYSFFMPSSEWLGLTLIAVWGGCAGLALSHSWRRHLRQHHLLEQALLSRNALHIVIGIVVIGSIQLLLVYGAFLLVQPVGMSKGWAWIPSSLLFWIFTFVAWTVFYATVLSRRRIRHTELEKLQLEIYLKENELRALQAQINPHFFFNSLNSIRALIYHDADAAAEMIDQLSNMMRYTLQVGQTTTVTLAQEWAAVRSYLSIEKIRFAERIKVTEQMDSAFDQLEIPPMVLQILVENAVKYGVEQRSSECQIELRVQRQDKHLQIQVANQGRLATIITTNNSTRLGINNIAKRLQLLYGEQASIGIEERDGWVIATLLLPLPSTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1J2</accession>
    <name>A0A2S9H1J2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_1460</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPF0126 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93851">
        <property type="protein sequence ID" value="PRC93851"/>
        <property type="gene ID" value="S2091_1460"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005115">
        <property type="entry name" value="Gly_transporter"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03458">
        <property type="entry name" value="Gly_transporter"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="29"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="62"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="89"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="116"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="148"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="172"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="domain" description="Gly_transporter" evidence="8">
        <location>
            <begin position="7"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="domain" description="Gly_transporter" evidence="8">
        <location>
            <begin position="91"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF03458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC93851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="207" mass="22368" checksum="958AEDE2CBA0BAEC" modified="2018-07-18" version="1">MLLHTIYLIAIVAEAMSGAIMGMRRDMDLFGICVVGTITALGGGTIRDILLGNYPLGWIIHPQYLLFTIGAAIVTAFVARFLHHLRSVFLMVDGLGLVAFSVIGCDIARANGMVPGIVILAGMITGVFGGLLRDVLCNEIPLVLQRELYATIALFTGSLYVGLLWLNVDPTIAPLVAIGCGFLYRLLAMRFHWKLPSFNGSGIRGFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1Q1</accession>
    <name>A0A2S9H1Q1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1496</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93887">
        <property type="protein sequence ID" value="PRC93887"/>
        <property type="gene ID" value="S2091_1496"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="169" mass="19318" checksum="2CD28D380E779A2F" modified="2018-07-18" version="1">MVKYAEIYGDDEVPDSLKVPGVNKQDAWWAIESEADSHAAAASLASLSLTKYRYMIAKQATSEMFSMHGMLLSFYFVLFDLLKSGNDIRHPTPVFRKAICQPSLDRLCEKMQLNPRAATEHMIMADFNVLSEVLKLKIDVMPYFDAINWMLGLDELLERMGMRVFRKQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1S0</accession>
    <name>A0A2S9H1S0_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6">Flagellar basal body rod protein FlgB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_1516</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 6">Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Bacterial flagellum basal body</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the flagella basal body rod proteins family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93907">
        <property type="protein sequence ID" value="PRC93907"/>
        <property type="gene ID" value="S2091_1516"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030694">
        <property type="term" value="C:bacterial-type flagellum basal body, rod"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071973">
        <property type="term" value="P:bacterial-type flagellum-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001444">
        <property type="entry name" value="Flag_bb_rod_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019776">
        <property type="entry name" value="Flagellar_basal_body_rod_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006300">
        <property type="entry name" value="FlgB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00460">
        <property type="entry name" value="Flg_bb_rod"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002889">
        <property type="entry name" value="Rod_FlgB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00588">
        <property type="entry name" value="FLAGELLA_BB_ROD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0975">Bacterial flagellum</keyword>
    <keyword evidence="8" id="KW-0966">Cell projection</keyword>
    <keyword evidence="8" id="KW-0969">Cilium</keyword>
    <keyword evidence="8" id="KW-0282">Flagellum</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flg_bb_rod" evidence="7">
        <location>
            <begin position="16"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00014376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00024934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR002889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC93907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="127" mass="13775" checksum="05FE08C9C9DA2C34" modified="2018-07-18" version="1">MIHKTEAVTSSMLKLALDAASLNHQAIANNIANINTVGYSPVRVNFEEQLDSIRQTLEQGGKVKADMLSGIQPVIERGQPFGDGDRTATLDMETAKLAENTVHYEALLKVMGMRMSMVGSAISEGKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1S6</accession>
    <name>A0A2S9H1S6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative protease with the C-terminal PDZ domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1118</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC93945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93945">
        <property type="protein sequence ID" value="PRC93945"/>
        <property type="gene ID" value="S2091_1118"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027268">
        <property type="entry name" value="Peptidase_M4/M1_CTD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024191">
        <property type="entry name" value="Peptidase_M61"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007963">
        <property type="entry name" value="Peptidase_M61_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040756">
        <property type="entry name" value="Peptidase_M61_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13180">
        <property type="entry name" value="PDZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05299">
        <property type="entry name" value="Peptidase_M61"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17899">
        <property type="entry name" value="Peptidase_M61_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016493">
        <property type="entry name" value="Glycyl_aminpptds"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="SSF50156"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PDZ" evidence="2">
        <location>
            <begin position="484"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="591"/>
            <end position="615"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="615" mass="68630" checksum="03D8BAFB5CECEA49" modified="2018-07-18" version="1">MTIHYTIIPKDLAGHLFQVTVRVDQPDPIGQVFILPAWIPGSYMVREFARNIVQIKASCNGKKVRLTKLDKHSWQAVPVSGSLTLEYEVYAWDLSVRTAHLDQTHGFYNGTSVFLRVVGQEMDSHVVDIQKPVDPACKQWRVATSLPLLKAKLYGFGSYVAENYDALIDHPVEMGEFAMASFSVHGVPHDFVVTGRVPNLDLDRIVRDLEKICATQIAFFEPKTKRAPMDRYVFMTMAVGDGYGGLEHRASTALICNRTDLPVKGNEGNEDASEAYISFLGLCSHEYFHTWNVKRIKPAAFAAYDLQQENYTPLLWLFEGITSYYDDLILLRSGIIDESAYLNMVSKTLNGVLRGAGRTKQSLADSSFDAWTKYYRQDENSPNAIVSYYTKGSLLALALDLTIRQTTAGKKSLDDLMRALWQTFGRDFYKLALTGDQQGVTEAQVEAMVEQICGVKMKPFFDRYVRGTADLPLDDMYADFGVGLVDQRKVRQPSLGVKLSREANDCKLAQVFNGRAAHAAGMSAGDVIVAIDGLRVSATDVPTNLSKLLGRYAVGARVVVHAFRRDELMQFTVRLQSDDVPMWALQVNEQDPASKSRVKVKQTAQLARPSSLKSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1T8</accession>
    <name>A0A2S9H1T8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1537</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93928">
        <property type="protein sequence ID" value="PRC93928"/>
        <property type="gene ID" value="S2091_1537"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="83" mass="8251" checksum="805625ECC567AE27" modified="2018-07-18" version="1">MCQRGVLGDGGCSLRGDPTGRTHGLCIVDSFDLQTSGIVDVLRDIAVAVDLGIFAAQRVVEIPGGDAGGVGTGAQASIGIVVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1T9</accession>
    <name>A0A2S9H1T9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1536</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93927">
        <property type="protein sequence ID" value="PRC93927"/>
        <property type="gene ID" value="S2091_1536"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="102" mass="10185" checksum="CF64313F9A9178FD" modified="2018-07-18" version="1">MHGADYAERIGAAHQLTECVVGIVRLPAVGVNTLQQLAIGGVNVVRGAGADAIAVAVHTGVGGDAAQVASEIVAVVRQLGLGGILGSLPCFDGRYADVLIGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1U9</accession>
    <name>A0A2S9H1U9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1137</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC93964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93964">
        <property type="protein sequence ID" value="PRC93964"/>
        <property type="gene ID" value="S2091_1137"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002656">
        <property type="entry name" value="Acyl_transf_3_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01757">
        <property type="entry name" value="Acyl_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="90"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="160"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="195"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="233"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="259"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="335"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl_transf_3" evidence="2">
        <location>
            <begin position="7"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="396" mass="46492" checksum="F5DB7C94DB8BCDE9" modified="2018-07-18" version="1">MNRRISDIQLLRGIAVIFVLVEHTQYNLFTQPSHLLELLYHYFGGWTGVDLFFAISGFVIARDLIPRLNRDDDRQFSTILSFWARRASRLWPSAWLWLMLILVATVSFNRSGAFGELKVNLDATLAGLFNYANFRVVETFGRSPYGASFPYWSLSLEEQFYLLLPLVAIVFRRWLPLALAIPLIYQFFSNRHFDLILMQTRSDAIILGVLLAIWSNHDSYRRLEPTFLKNHRWLRWIILTTLLFLLGAIGSYRFMEYRFWIGIVALISIVLVFIGSYDKDYLMPNNPLKDIFLWFGSRSYALYLTHIPAYFCSREIWCRVEPVNTIFDKTYDPRLALTAIALTLIFGELNYRFIETPFRAHGKRFADRINFSSDWLKRRISKLKDYSAISTGKERS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1X5</accession>
    <name>A0A2S9H1X5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1141</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC93968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93968">
        <property type="protein sequence ID" value="PRC93968"/>
        <property type="gene ID" value="S2091_1141"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="107" mass="12205" checksum="F42A626ED3BF007C" modified="2018-07-18" version="1">MNHEEMPASDTAERLKILLKNNEKLFPTHLLASYPHIVGKLCAVWQEPVQASDYFKDLLTTQRENRAGFPAEIYTEIFALSDFYSSTHPSAKKNDDFWSGVNVARDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H201</accession>
    <name>A0A2S9H201_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Stringent starvation protein B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1160</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC93987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93987">
        <property type="protein sequence ID" value="PRC93987"/>
        <property type="gene ID" value="S2091_1160"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007481">
        <property type="entry name" value="SspB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036760">
        <property type="entry name" value="SspB-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37486">
        <property type="entry name" value="PTHR37486"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04386">
        <property type="entry name" value="SspB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005276">
        <property type="entry name" value="SspB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101738">
        <property type="entry name" value="SSF101738"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="154" mass="16818" checksum="C60905FAD1BBBB4D" modified="2018-07-18" version="1">MSETASTKPYLIRALYEWCTDNGYTPHIAVKVQGQVRVPMEFVRNGDIVLNIAFSACSGLQMDNLAISFKARFGGVSRDIYVPIEAIAAIYASENGQGMAFEVSSELVNKEIAPSPVTEKPAMTLAITNTDDSSAKTETNLKEIRKKPSLTIIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H210</accession>
    <name>A0A2S9H210_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1197</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94024">
        <property type="protein sequence ID" value="PRC94024"/>
        <property type="gene ID" value="S2091_1197"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021457">
        <property type="entry name" value="DUF3108"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11306">
        <property type="entry name" value="DUF3108"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015393051" evidence="1">
        <location>
            <begin position="24"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="253" mass="28057" checksum="0EFE7165EB8CC6F6" modified="2018-07-18" version="1">MKFSLSLSLIFASLQLLSTAVLAEEHPSINYPTNLAPSAQLHYHIKAKQSGFSLDGEADVNWQVGGSNSTQTYSIKTETRAAILGKILQADSTGLIDSFGLAPDQFEEKRLGKPATQTRFDRKTKTLNFSESSETYPLKGGEQDRTSAVWQLVSIARAAPAQFIPNSQWKLFVAGRRDAEKWTFTVDDNVTISTPFGNVATVHIIKAPPPDSKDQRLDIWLAPSMEWYPVRLKFSDANGDTIDQILDRVKNNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H235</accession>
    <name>A0A2S9H235_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1224</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94051">
        <property type="protein sequence ID" value="PRC94051"/>
        <property type="gene ID" value="S2091_1224"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="36" mass="4184" checksum="D7B4FF040A264005" modified="2018-07-18" version="1">MLIVIAANKIILDTVSAYLSQFLARRGNIFLWQRFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2B8</accession>
    <name>A0A2S9H2B8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">5'-3' exonuclease (Including N-terminal domain of PolI)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1281</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94108">
        <property type="protein sequence ID" value="PRC94108"/>
        <property type="gene ID" value="S2091_1281"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017108">
        <property type="term" value="F:5'-flap endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033567">
        <property type="term" value="P:DNA replication, Okazaki fragment processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09898">
        <property type="entry name" value="H3TH_53EXO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020046">
        <property type="entry name" value="5-3_exonucl_a-hlix_arch_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002421">
        <property type="entry name" value="5-3_exonuclease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036279">
        <property type="entry name" value="5-3_exonuclease_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020045">
        <property type="entry name" value="DNA_polI_H3TH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038969">
        <property type="entry name" value="FEN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008918">
        <property type="entry name" value="HhH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42646">
        <property type="entry name" value="PTHR42646"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01367">
        <property type="entry name" value="5_3_exonuc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02739">
        <property type="entry name" value="5_3_exonuc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00475">
        <property type="entry name" value="53EXOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00279">
        <property type="entry name" value="HhH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47807">
        <property type="entry name" value="SSF47807"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="SSF88723"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="53EXOc" evidence="2">
        <location>
            <begin position="2"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="264" mass="29312" checksum="9CCDF84FBD1591F8" modified="2018-07-18" version="1">MAKLLAIDGLNIVRRIYEANPEPDSPEKAETALRFSLSAFHKLHHEHTPSHIVAAFDFGGTTWRHALYDKYREQRAPMPDALRQSLPTLYAELEKFGIKVLCIPEVEADDVIGTVVLRWLAEGRGEAIVVSTDKDLHVLIAHGALIWDHFKNEWHDSAWVQNKFGVPPEQLEQLLALMGDPTDGIPGVTKVGMKTAAKLLQAYGSIDAIMAGAGILKNTVGENLRKDAKILALSRQLVVLKSDVQLGVTWKMLAMPTDGQHERF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2I5</accession>
    <name>A0A2S9H2I5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">GGDEF: diguanylate cyclase (GGDEF) domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_1343</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94170">
        <property type="protein sequence ID" value="PRC94170"/>
        <property type="gene ID" value="S2091_1343"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01948">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001633">
        <property type="entry name" value="EAL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035919">
        <property type="entry name" value="EAL_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00563">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00052">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141868">
        <property type="entry name" value="SSF141868"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50883">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="274"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="3">
        <location>
            <begin position="296"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="4">
        <location>
            <begin position="390"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="domain" description="EAL" evidence="2">
        <location>
            <begin position="530"/>
            <end position="783"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC94170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="787" mass="86889" checksum="B644D86CE1B42EE0" modified="2018-07-18" version="1">MRSIESRIVTLFILIILGVQLAGFFSLRSALESKARSSMEMGLAHSERAIQRLLDQHTMKLTEKVTKLTSDSNFLEALSNVSNADSIKIESILAKQCAQMNASMGMLIGMDNQIQVTSSRQLSSQLKQASIALISGAEQQGYASSIVVNNHYPTQLIAALLKTPTSTAWIVMAFPLENNIILEMRQLTPLQVTMLIKDKQYWQVVSSSLSNSEAETLAKNVPSSIATEAKKVVLNDSEYSMEMMALTKPPSADAIVVIQGSISDMVAPYNKIQIGLILLTLFSLAVAVIGSITFTKRISQPLRQLRDIAKRLGAGDYDSPIQVSGDGEISELAHAFVSMRDGIAHRENEIKRLAYWDTLTDLPNRAQFTFLLKQAIAATKAVAATEQTSQSCFVLMMDLDRFKHVNDIMGHSFGDLLLKKVASRLREALPGAQLARLGGDEFALLLPNSNLNAAQEAALIILLMLEQPITLEDQAVDLGAGIGLAGYPEHGEDAEILLSHAEVAMYAAKRNVGSNFTVYRPEIDQSSQQNLSLLSELRCAIQENQLRLYVQPKLSLGEKEVVGIEALMRWEHPTRGFLVPDQFIPFAEQTGIIRLLTRWILDKSAALCTELITHGIHLKISVNISTHDLLDQDLPVKFADILTRHRVKTSSFCLEITESAIMNDPHRAQVTLERLNAMGVELSIDDFGTGYSSLAYLKRLPVDELKIDKSFVMHMENDSDDRKIVKSTIDLGHNMGLRVVAEGVEDAAVMALLTKMGCDQAQGNYINRAIPSEQLIEWLGQKETLFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2R1</accession>
    <name>A0A2S9H2R1_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Protein TonB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">S2091_0879</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Cell inner membrane</location>
            <topology evidence="1 9">Single-pass membrane protein</topology>
            <orientation evidence="1 9">Periplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the TonB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94258">
        <property type="protein sequence ID" value="PRC94258"/>
        <property type="gene ID" value="S2091_0879"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030288">
        <property type="term" value="C:outer membrane-bounded periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031992">
        <property type="term" value="F:energy transducer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015343">
        <property type="term" value="F:siderophore transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003538">
        <property type="entry name" value="TonB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006260">
        <property type="entry name" value="TonB/TolA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037682">
        <property type="entry name" value="TonB_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03544">
        <property type="entry name" value="TonB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01374">
        <property type="entry name" value="TONBPROTEIN"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01352">
        <property type="entry name" value="tonB_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="4 9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="6 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="55"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_C" evidence="11">
        <location>
            <begin position="182"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="119"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU362123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF03544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PRC94258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="261" mass="27091" checksum="8EADDFEFD7D99DEF" modified="2018-07-18" version="1">MTTMTFASIHGAPRRAAARRIYTTAQRFESTSTPPAAAVAVIGNVTDAKRSRDQIGLIATVGIVIALHAAIITIVNQSVETAPIPSKASMLAVDIAPPPPPPPIIKPKPLPQIAAVKPVTRQPSTSVPTVPSVTETPAPSAETVQVAVATPSVPAPAPTLAPAPAPEPVTEPRGYAGYLNNPAPSYPLAAQKHGLQGKVILKIHVLTNGQPDNISVAKSSGYAILDEAAVKAVTAWIFEPAKRGQKPIDGWVNVPINFNLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2R8</accession>
    <name>A0A2S9H2R8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phenylacetate-CoA oxygenase, PaaG subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0895</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94274">
        <property type="protein sequence ID" value="PRC94274"/>
        <property type="gene ID" value="S2091_0895"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097266">
        <property type="term" value="F:phenylacetyl-CoA 1,2-epoxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010124">
        <property type="term" value="P:phenylacetate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012347">
        <property type="entry name" value="Ferritin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011881">
        <property type="entry name" value="PaaA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007814">
        <property type="entry name" value="PaaA_PaaC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05138">
        <property type="entry name" value="PaaA_PaaC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="SSF47240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02156">
        <property type="entry name" value="PA_CoA_Oxy1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="319" mass="36440" checksum="5B6E312C3C7BB8C6" modified="2018-07-18" version="1">MNDNMPSLEQAFQQQIDSKCKVEPQDWMPPAYRQSLTRQIAQHAHSEYVGMLPEAAWITRAPTLQRKSILLAKVQDEAGHAQYLYAALETLGVGREQAYLQLLNGAAKYLNIFNYPAMNWADVGMIGWLTDGAAIVNQVPLSRSSYGPYARAMIRICQEESFHHRQGFDLIRTMTEGTPQQRQMAQDALDRWWWPTLMVFGPPDADSPHSQRSMQWGIKLFSNDELRQKFIDQTVPQVHYLGLRVPDPCLKLDRESGHYKIGPIDWDEFKRSINGQGMCNQDRIQARNKAWEDGSWVREATAAYADKQAALKTEGNVNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2S7</accession>
    <name>A0A2S9H2S7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0905</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94284">
        <property type="protein sequence ID" value="PRC94284"/>
        <property type="gene ID" value="S2091_0905"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01743">
        <property type="entry name" value="GATase1_Anthranilate_Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006221">
        <property type="entry name" value="TrpG/PapA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00566">
        <property type="entry name" value="trpG_papA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GATase" evidence="1">
        <location>
            <begin position="4"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="204" mass="22253" checksum="7BF7021BFD60240F" modified="2018-07-18" version="1">MHLMIDNYDSFTYNVVQYLSMLGAEIEVRRSDQISLEQIDAMAPQSLIISPGPCSPTEAGISIAAIRHFAGRLPILGICLGHQCIAAAMGGQVRRAEEVLHGKISPIQHAGDGLFAGIPQQGLVGRYHSLVVDALPPELLVTARALRPDGSEGEIMAMQHRHLPIYGMQFHPESVLTQHGLGMLANYMRIVTQFELEGGTRIHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H352</accession>
    <name>A0A2S9H352_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Alkylated DNA repair protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_1033</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94412">
        <property type="protein sequence ID" value="PRC94412"/>
        <property type="gene ID" value="S2091_1033"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.590">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004574">
        <property type="entry name" value="Alkb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027450">
        <property type="entry name" value="AlkB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037151">
        <property type="entry name" value="AlkB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16557">
        <property type="entry name" value="PTHR16557"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13532">
        <property type="entry name" value="2OG-FeII_Oxy_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5" id="KW-0234">DNA repair</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="6">
        <location>
            <begin position="115"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC94412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="215" mass="23655" checksum="CBA79D7521E270B7" modified="2018-07-18" version="1">MTLELFPLEHSDEPEAIGPGSFVLRGFALPYVDEILPAVAALERCSGFRNMITPGGFTMSVAMTNCGQFGWTTDRRGYRYTQIDPDTGQPWPLMPIAFMRLAQAAASAAGFADFVADACLLNRYLPGSRLSLHQDKNERDFAAPIVSVSLGMPAVFLFGGLDRTDKPARIPLMHGDVVVWGGVDRLRYHGVMPLKEKPHSLLGSQRLNLTFRKAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H398</accession>
    <name>A0A2S9H398_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0957</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94336">
        <property type="protein sequence ID" value="PRC94336"/>
        <property type="gene ID" value="S2091_0957"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="16"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="113" mass="12374" checksum="AE9EBA2033170A18" modified="2018-07-18" version="1">MKIDERVLAQVIGKAISKRRLACNLTQEDVAERLNIGTEAVSRMERGTVMPTVSRLVELADIFNSQVGDLLIESSNRAKDQGKLITNLINALSPKDRAFVVGIVESLTEHLGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3D3</accession>
    <name>A0A2S9H3D3_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glucose-6-phosphate isomerase</fullName>
            <shortName evidence="7">GPI</shortName>
            <ecNumber evidence="7">5.3.1.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Phosphoglucose isomerase</fullName>
            <shortName evidence="7">PGI</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Phosphohexose isomerase</fullName>
            <shortName evidence="7">PHI</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">pgi</name>
        <name evidence="9" type="ORF">S2091_0495</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7 8">
            <text>alpha-D-glucose 6-phosphate = beta-D-fructose 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:11816"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="ChEBI" id="CHEBI:58225"/>
            <dbReference type="EC" id="5.3.1.9"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Carbohydrate biosynthesis; gluconeogenesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 7 8">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7 8">Belongs to the GPI family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.9" evidence="7"/>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94492">
        <property type="protein sequence ID" value="PRC94492"/>
        <property type="gene ID" value="S2091_0495"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00181"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00138"/>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097367">
        <property type="term" value="F:carbohydrate derivative binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004347">
        <property type="term" value="F:glucose-6-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd05015">
        <property type="entry name" value="SIS_PGI_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05016">
        <property type="entry name" value="SIS_PGI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00473">
        <property type="entry name" value="G6P_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001672">
        <property type="entry name" value="G6P_Isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023096">
        <property type="entry name" value="G6P_Isomerase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018189">
        <property type="entry name" value="Phosphoglucose_isomerase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046348">
        <property type="entry name" value="SIS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035476">
        <property type="entry name" value="SIS_PGI_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035482">
        <property type="entry name" value="SIS_PGI_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11469">
        <property type="entry name" value="PTHR11469"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00342">
        <property type="entry name" value="PGI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00662">
        <property type="entry name" value="G6PISOMERASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53697">
        <property type="entry name" value="SSF53697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00174">
        <property type="entry name" value="P_GLUCOSE_ISOMERASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51463">
        <property type="entry name" value="P_GLUCOSE_ISOMERASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 7 8" id="KW-0312">Gluconeogenesis</keyword>
    <keyword evidence="4 7 8" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="5 7 8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton donor" evidence="7">
        <location>
            <position position="352"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="383"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="505"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC94492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="538" mass="59289" checksum="3B7FC24143D6D337" modified="2018-07-18" version="1">MATSVSHTPLWCLLQQRATNTPSIKELFKSEPQRFNHFSASACGILLDYSKQRLDTTAKLNLLALARQQKVEARRDAMFAGEAINHTENRAVLHTVLRLPKGEAFHHQGENIAASVHAVLQQMRTFSDAVREGRWLGFSGKPIRTIVNIGIGGSDLGPQMACIALAPWSQKNLLLHFVSNVDGRHLTDALKNAEPETTLFVVASKTFSTMETLTNAQTAREWMLAHGCPSEQIRQHFVALSTNVEAASKFGIAPDNVFPFWNWAGGRYSVWSAIGLSIALYVGADKFEEMLAGAHEMDLHFQQAPLEQNLPVLMALLGVWNINFLGLQALSIAPYHQRMARLPAYLQQLEMESNGKSVTREGQRVDYATSPILFGEAGTNGQHAYFQLLHQGATIIPTDFIVVADDDVGLPGHNQALLANCFAQSKAMALGKDITQVRAELPGVSEALLPHRVFEGNRPSSTVLLDVLSPKSLGALIALYEHKVFVQSVIWDINAFDQWGVELGKSLAQQLISLKPEAVKEDYDSSTKGLLRALKRDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3I2</accession>
    <name>A0A2S9H3I2_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">High-potential iron-sulfur protein</fullName>
            <shortName evidence="2">HiPIP</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_0541</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Specific class of high-redox-potential 4Fe-4S ferredoxins. Functions in anaerobic electron transport in most purple and in some other photosynthetic bacteria and in at least one genus (Paracoccus) of halophilic, denitrifying bacteria.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the high-potential iron-sulfur protein (HiPIP) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94538">
        <property type="protein sequence ID" value="PRC94538"/>
        <property type="gene ID" value="S2091_0541"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019646">
        <property type="term" value="P:aerobic electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.490.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000170">
        <property type="entry name" value="High_potential_FeS_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036369">
        <property type="entry name" value="HIPIP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01355">
        <property type="entry name" value="HIPIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57652">
        <property type="entry name" value="SSF57652"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51373">
        <property type="entry name" value="HIPIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="2" id="KW-0249">Electron transport</keyword>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1 2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015755509" description="High-potential iron-sulfur protein" evidence="3">
        <location>
            <begin position="35"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="domain" description="HIPIP" evidence="4">
        <location>
            <begin position="28"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000620"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51373"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC94538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="97" mass="10361" checksum="28FFB448619BDD75" modified="2018-07-18" version="1">MQKKNMSSRRQFIKLGSLALSALPLLFLSGKASAATNTGMRTAMKYQDKPNGDKSCSGCAQFVPGKSAKDLGGCKLFPGDTEISPNGFCIAWMVKPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3J3</accession>
    <name>A0A2S9H3J3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0557</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94554">
        <property type="protein sequence ID" value="PRC94554"/>
        <property type="gene ID" value="S2091_0557"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="70"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="100" mass="11236" checksum="95B3583D61825544" modified="2018-07-18" version="1">MMQTISKMQAEDEENLLLAKARARANYLDHLKLQMPKWNAKALCIELAIIVVCYACVAIYNWLFNASIPPVLGIITGAVNGCLVAWCITRTEPKSKKDKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3Q0</accession>
    <name>A0A2S9H3Q0_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 4">Orotate phosphoribosyltransferase</fullName>
            <shortName evidence="4">OPRT</shortName>
            <shortName evidence="4">OPRTase</shortName>
            <ecNumber evidence="2 4">2.4.2.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">pyrE</name>
        <name evidence="6" type="ORF">S2091_0615</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>diphosphate + orotidine 5'-phosphate = 5-phospho-alpha-D-ribose 1-diphosphate + orotate</text>
            <dbReference type="Rhea" id="RHEA:10380"/>
            <dbReference type="ChEBI" id="CHEBI:30839"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57538"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="EC" id="2.4.2.10"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="1 4">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; UMP from orotate: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.10" evidence="2 4"/>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94612">
        <property type="protein sequence ID" value="PRC94612"/>
        <property type="gene ID" value="S2091_0615"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00070">
        <property type="reaction ID" value="UER00119"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004588">
        <property type="term" value="F:orotate phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044205">
        <property type="term" value="P:'de novo' UMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01208">
        <property type="entry name" value="PyrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023031">
        <property type="entry name" value="OPRT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004467">
        <property type="entry name" value="Or_phspho_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRibTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00156">
        <property type="entry name" value="Pribosyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00336">
        <property type="entry name" value="pyrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 4" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pribosyltran" evidence="5">
        <location>
            <begin position="45"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Orotate binding" evidence="4">
        <location>
            <begin position="34"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="5-phosphoribose 1-diphosphate binding" evidence="4">
        <location>
            <begin position="72"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="5-phosphoribose 1-diphosphate binding" evidence="4">
        <location>
            <begin position="123"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="26"/>
        </location>
        <ligand>
            <name>5-phospho-alpha-D-ribose 1-diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="98"/>
        </location>
        <ligand>
            <name>5-phospho-alpha-D-ribose 1-diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="99"/>
        </location>
        <ligand>
            <name>5-phospho-alpha-D-ribose 1-diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="102"/>
        </location>
        <ligand>
            <name>5-phospho-alpha-D-ribose 1-diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="104"/>
        </location>
        <ligand>
            <name>5-phospho-alpha-D-ribose 1-diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="127"/>
        </location>
        <ligand>
            <name>orotate</name>
            <dbReference type="ChEBI" id="CHEBI:30839"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="155"/>
        </location>
        <ligand>
            <name>orotate</name>
            <dbReference type="ChEBI" id="CHEBI:30839"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC94612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="221" mass="23655" checksum="7C4D72F83A8C76BE" modified="2018-07-18" version="1">MKNLRQEFIAFSVQAGVLSFGEFITKAGRTSPYFFNAGLFNEGANLGQLAQFYAQTLLDSGIEFDMLFGPAYKGITLASSTAVALAGMGRNVPFAYNRKEAKDHGEGGTIVGAKLAGKVVIIDDVISAGTSVRESVDMIRAAGATPSAVLIALDRMERSGKDDALTVNSAVQEIINTYQMPVICIANLADLFDYLSSGQASQFEQYTAAVRDYRAKYGSQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3U0</accession>
    <name>A0A2S9H3U0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0539</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94536">
        <property type="protein sequence ID" value="PRC94536"/>
        <property type="gene ID" value="S2091_0539"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010869">
        <property type="entry name" value="DUF1501"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07394">
        <property type="entry name" value="DUF1501"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015553879" evidence="1">
        <location>
            <begin position="25"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="406" mass="44001" checksum="3CBA5995AC76909B" modified="2018-07-18" version="1">MKRRQFLQAMAASSLPLLSSKLFAAPSTQPRLLFVFLRGGYDAASLLVPTSSTFYSEVRPNIGIARSGTDANAVISLNSDWGLHPALRDSIYPLYAKGQAAFIPFAGTDDLSRSHFETQDSIELGQPLQGRRDLSSGFLNRLATVLNKDSNSVATMSFTEQLPLVMQGSMQIANAGVKNVGNSAIDARQSQLIANMYQGKALSKQVDEGFVVRDQVKQQMDQMQAEDKTKEMTDASRNAISTKGFGLEARRIGKLMQQQYGLGFVDVGGWDTHVNQGGANGALATKFKELGTGLAAFADEMGSAWDTTTVVVISEFGRTFRENGNRGTDHGHGTVYWVLGGAVHGGKIVGEQCAVEQKTLFQNRDFPVLNEYRSTLGGLFARMYGLSPKQLDYVFAGVKGNDLGLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4E9</accession>
    <name>A0A2S9H4E9_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Acetylornithine aminotransferase</fullName>
            <shortName evidence="2">ACOAT</shortName>
            <ecNumber evidence="2">2.6.1.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">argD</name>
        <name evidence="4" type="ORF">S2091_0008</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>2-oxoglutarate + N(2)-acetyl-L-ornithine = L-glutamate + N-acetyl-L-glutamate 5-semialdehyde</text>
            <dbReference type="Rhea" id="RHEA:18049"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29123"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57805"/>
            <dbReference type="EC" id="2.6.1.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
        <text evidence="2">Binds 1 pyridoxal phosphate per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 4/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="2">May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.11" evidence="2"/>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94813">
        <property type="protein sequence ID" value="PRC94813"/>
        <property type="gene ID" value="S2091_0008"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00068">
        <property type="reaction ID" value="UER00109"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003992">
        <property type="term" value="F:N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006526">
        <property type="term" value="P:arginine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00610">
        <property type="entry name" value="OAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01107">
        <property type="entry name" value="ArgD_aminotrans_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017652">
        <property type="entry name" value="Ac/SucOrn_transaminase_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004636">
        <property type="entry name" value="AcOrn/SuccOrn_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000521">
        <property type="entry name" value="Transaminase_4ab_Lys_Orn"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03246">
        <property type="entry name" value="arg_catab_astC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00707">
        <property type="entry name" value="argD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00600">
        <property type="entry name" value="AA_TRANSFER_CLASS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="2" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 2 3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Pyridoxal phosphate binding" evidence="2">
        <location>
            <begin position="114"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Pyridoxal phosphate binding" evidence="2">
        <location>
            <begin position="232"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="147"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="150"/>
        </location>
        <ligand>
            <name>N(2)-acetyl-L-ornithine</name>
            <dbReference type="ChEBI" id="CHEBI:57805"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="289"/>
        </location>
        <ligand>
            <name>N(2)-acetyl-L-ornithine</name>
            <dbReference type="ChEBI" id="CHEBI:57805"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="290"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="2">
        <location>
            <position position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC94813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="411" mass="43835" checksum="F503627E1FBB528C" modified="2018-07-18" version="1">MTATTTNTPPNTPVTRSTFDDVIVPTYAPSTLVPVRAKGLDLWDQEGRQYLDFTAGIAVTSLGHCHPDVVHTLQQQAEKLWHVGNGYTNEPVLELARSLVAATFADRAFFCNSGAEANEAALKLARKYAAKNGHTHKTRIISCENSFHGRTLFTVSVGGQPKYTEGFGPLPADLTHIAFNDITAAREAMGNDVCAVMVEPVQGEGGVMPATTEYLQALRELCDQHGALLIFDEVQCGMGRTGQLFAYMGYGVTPDILTSAKALGNGYPVGAMLTTNTVAAAFAVGTHGTTYGGNPLAASVALTVLRTINVPSFLLRVKHASKTLILALQGLVQEFPHMLAEVRGSGLLLGVQLTATYAGRAKEMTKAAEEQGLMLLIAGPDVLRFAPALIVTDEQIQEAATRLRRALATLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4J4</accession>
    <name>A0A2S9H4J4_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Riboflavin biosynthesis protein</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="12">Riboflavin kinase</fullName>
                <ecNumber evidence="12">2.7.1.26</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="12">Flavokinase</fullName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="12">FMN adenylyltransferase</fullName>
                <ecNumber evidence="12">2.7.7.2</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="12">FAD pyrophosphorylase</fullName>
            </alternativeName>
            <alternativeName>
                <fullName evidence="12">FAD synthase</fullName>
            </alternativeName>
        </domain>
    </protein>
    <gene>
        <name evidence="14" type="ORF">S2091_0058</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 12">
            <text>ATP + FMN + H(+) = diphosphate + FAD</text>
            <dbReference type="Rhea" id="RHEA:17237"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
            <dbReference type="EC" id="2.7.7.2"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>ATP + riboflavin = ADP + FMN + H(+)</text>
            <dbReference type="Rhea" id="RHEA:14357"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57986"/>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.26"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4 12">Cofactor biosynthesis; FAD biosynthesis; FAD from FMN: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5 12">Cofactor biosynthesis; FMN biosynthesis; FMN from riboflavin (ATP route): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the ribF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.26" evidence="12"/>
    <dbReference type="EC" id="2.7.7.2" evidence="12"/>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94863">
        <property type="protein sequence ID" value="PRC94863"/>
        <property type="gene ID" value="S2091_0058"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00276">
        <property type="reaction ID" value="UER00406"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00277">
        <property type="reaction ID" value="UER00407"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003919">
        <property type="term" value="F:FMN adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008531">
        <property type="term" value="F:riboflavin kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006747">
        <property type="term" value="P:FAD biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009398">
        <property type="term" value="P:FMN biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02064">
        <property type="entry name" value="FAD_synthetase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004821">
        <property type="entry name" value="Cyt_trans-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015864">
        <property type="entry name" value="FAD_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023468">
        <property type="entry name" value="Riboflavin_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002606">
        <property type="entry name" value="Riboflavin_kinase_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015865">
        <property type="entry name" value="Riboflavin_kinase_bac/euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023465">
        <property type="entry name" value="Riboflavin_kinase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22749">
        <property type="entry name" value="PTHR22749"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06574">
        <property type="entry name" value="FAD_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01687">
        <property type="entry name" value="Flavokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004491">
        <property type="entry name" value="FAD_Synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00904">
        <property type="entry name" value="Flavokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82114">
        <property type="entry name" value="SSF82114"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00125">
        <property type="entry name" value="cyt_tran_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00083">
        <property type="entry name" value="ribF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10 12" id="KW-0274">FAD</keyword>
    <keyword evidence="6 12" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7 12" id="KW-0288">FMN</keyword>
    <keyword evidence="12" id="KW-0418">Kinase</keyword>
    <keyword evidence="9 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Flavokinase" evidence="13">
        <location>
            <begin position="187"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00002121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00005201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRNR" id="PIRNR004491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="PRC94863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="325" mass="35225" checksum="ED463F2EEBB5E247" modified="2018-07-18" version="1">MKVFRGLSHSIPSNPCALTIGNFDGVHLGHQALLAQVRQAADRLNLTASVMTFEPHPREFFAHRAGDPSKAPSRIANLRDNMNAMANAGMDNIIVEHFNATFASQSPQEFIEKVLVKGLHVKWLMVGEDFCFGAKRAGNIALLKEAGQQLGFSVETLPTVTSGGQRVSSSAVRAALAQGDFAQTHALIGHPYSITGRVVHGQKLGRTIGFPTLNLRIAHQHPAVHGIFTVQVHGLADHPLPAVASIGVRPTVEDAGRVLLETHIFDYDQSCYGKLVQIEFLQKIRDEKKFPDLATMTAAIDADAAQARAYFSTPGLRTISATDRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4W3</accession>
    <name>A0A2S9H4W3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative aminoglycoside phosphotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0219</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95024">
        <property type="protein sequence ID" value="PRC95024"/>
        <property type="gene ID" value="S2091_0219"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05154">
        <property type="entry name" value="ACAD10_11_N-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041726">
        <property type="entry name" value="ACAD10_11_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="APH" evidence="1">
        <location>
            <begin position="38"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC95024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="356" mass="40265" checksum="3DA3A890EDF5FABC" modified="2018-07-18" version="1">MTLLDQAGKVRSGEELPLEQITAFLNNAGMNLNGIPELSQFPGGASNLTYLLKYADAELILRRPPIGHKAKSAHDMVREAKLMQALKPVYNYVPKVLAICEDSTIMGCDFYVMERIHGIIPRQNMPESLNLTVQDTHTLCLNVIDKMIALHQIDYQAAGLQGLGRGAGYVQRQISGWSERAVQAKTDNSADFSEIVAWLEQHKPAQDAATCLIHNDFRFDNVVLNPQNPLEVIGVLDWEMATLGDPLMDLGNTLAYWAQSDDDAIFLSMRRQPTHLPGMLTRQEVIAYYLEKMGLEVENSDFYVIFGLFRLAIIIQQIYYRYHHGQNKNPQFAEFVNITNYLQKRCLKLIANYSRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4X4</accession>
    <name>A0A2S9H4X4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0212</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95017">
        <property type="protein sequence ID" value="PRC95017"/>
        <property type="gene ID" value="S2091_0212"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="58"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="87"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="111"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="135"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="159"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC95017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="180" mass="20108" checksum="9B96B6EB5B6B843A" modified="2018-07-18" version="1">MITKQQAQEALIQIELTQQRSAELIGYWRSGIYVQVWGVVWIIAYLSCFFMPVNSGSIWLICDAIGGIATVILSIRDRKNEKQDKRITWAIVIIAAFGILVSTLISNRPGALPVFWTFLIMACYMLSGLWFGIRWIILGATVIALCMVTYLNFMPWFNLIMAIAGGGGLLLGGTWIARAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4X5</accession>
    <name>A0A2S9H4X5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0235</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95040">
        <property type="protein sequence ID" value="PRC95040"/>
        <property type="gene ID" value="S2091_0235"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034660">
        <property type="entry name" value="DinB/YfiT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018531">
        <property type="entry name" value="DUF1993"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36922">
        <property type="entry name" value="PTHR36922"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09351">
        <property type="entry name" value="DUF1993"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109854">
        <property type="entry name" value="SSF109854"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC95040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="168" mass="18593" checksum="7501D8878DAE0FF9" modified="2018-07-18" version="1">MTISMYNASVPVFKQMLASMSHVLAKAEVHSKEKKIDPAVFLQARLYPDMLPLVRQVQIAADFAKGVSARLANVEVPTHEDNEQSFADLQARISSTLAFIESLNQAQFEGAAAREVILRPGTPKEKKFTGLAYLCSYGLPQFFFHVTTTYAILRHNGVEIGKGDFMGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H584</accession>
    <name>A0A2S9H584_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Histidine ammonia-lyase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0347</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95152">
        <property type="protein sequence ID" value="PRC95152"/>
        <property type="gene ID" value="S2091_0347"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016841">
        <property type="term" value="F:ammonia-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00332">
        <property type="entry name" value="PAL-HAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.275.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001106">
        <property type="entry name" value="Aromatic_Lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024083">
        <property type="entry name" value="Fumarase/histidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008948">
        <property type="entry name" value="L-Aspartase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022313">
        <property type="entry name" value="Phe/His_NH3-lyase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10362">
        <property type="entry name" value="PTHR10362"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00221">
        <property type="entry name" value="Lyase_aromatic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48557">
        <property type="entry name" value="SSF48557"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00488">
        <property type="entry name" value="PAL_HISTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC95152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="518" mass="56667" checksum="706A00FEB74E14E8" modified="2018-07-18" version="1">MQHAEPTKNHSTISFDQSRLQIEDIVSIANKTASAALSPDPLFRAAITRGADFLDRLLAEDGTIYGVTTGYGDSCTVEIPPELIAELPHHLYTYHGCGLGEYFTPAQTRAVMAVRLASLCKGYSGVSVGLLEQITSLLKEDILPLIPSEGSVGASGDLTPLSYLAAVLCGEREVWRDGQHVPAAQALSEAGITPLRLRPKEGLAIMNGTAVMTALACLAYDRAEYLTKLTTRITAMASFALDGNAKHFDETLFSVKPHAGMQKVASWLRQDLQCEQTERNGKRLQDRYSIRCAPHVIGVLADALPFFRQSIENELNSANDNPIIDAEGEHVLHGGHFYGGHIAFAMDGMKNAVANLADLLDRQMALLVDSRYNHDLPSNLSGAVGPRAAINHGLKALQISASAWTAEALKLTMPASVFSRSTECHNQDKVSMGTIAARDCLRVLELTEQVVAALLITVRQGVWLRCRHTPAVMPEESLQQMMALLSADIPEIIEDRRLEPDLRLMLERIRHQNWTLYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H586</accession>
    <name>A0A2S9H586_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">LPS-assembly lipoprotein LptE</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">lptE</name>
        <name evidence="3" type="ORF">S2091_0296</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Component of the lipopolysaccharide transport and assembly complex. Interacts with LptD.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the LptE lipoprotein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95101">
        <property type="protein sequence ID" value="PRC95101"/>
        <property type="gene ID" value="S2091_0296"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043165">
        <property type="term" value="P:Gram-negative-bacterium-type cell outer membrane assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01186">
        <property type="entry name" value="LPS_assembly_LptE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007485">
        <property type="entry name" value="LPS_assembly_LptE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38098">
        <property type="entry name" value="PTHR38098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04390">
        <property type="entry name" value="LptE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="3" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="1 2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC95101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="168" mass="18993" checksum="187738D8E6E53B53" modified="2018-07-18" version="1">MMSFINRWWLVSAMLASVLLISACGFHLRGASEFPFKTIYVQGSETTPLGVSLRRNLKGQENTALVDNEKDADVVLDILSERPEKVILSLTVQGLVREYTLNSYLTFQVRNSDGKLFLPPTTIVLHRVISYNENVILSKAAEEAMLYKDMQGDLIQQVVRRLSVLKMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H593</accession>
    <name>A0A2S9H593_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glycosyl transferase family 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_0349</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95154">
        <property type="protein sequence ID" value="PRC95154"/>
        <property type="gene ID" value="S2091_0349"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="237"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_trans_2-like" evidence="3">
        <location>
            <begin position="20"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC95154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="264" mass="29377" checksum="87879F2D4483E92A" modified="2018-07-18" version="1">MTLATAIHCFDLEWQVLKFCVVIPVYDHEHAIGAVVAAVLAHKVPCILVDDGSSAGCAQKLDSLLAEVADPSQLKLLRLNVNSGKGAAVLAGFTYAASEGYTHVLQVDADGQHCTADIPQFLAAAAKQPEAIIAGCPVFDESVPKIRLYARYLTHIWVWINTLSFDIKDSMCGFRAYPVAAVMELIAHQKIGARMNFDTDILVRLYWQGLDVVNLPTRVTYPSDGVSHFRVWFDNVLITRMHIILFFGMLLRIPRLLVRKMNRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5G9</accession>
    <name>A0A2S9H5G9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NADPH:quinone reductase and related Zn-dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0429</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95234">
        <property type="protein sequence ID" value="PRC95234"/>
        <property type="gene ID" value="S2091_0429"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002364">
        <property type="entry name" value="Quin_OxRdtase/zeta-crystal_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01162">
        <property type="entry name" value="QOR_ZETA_CRYSTAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PKS_ER" evidence="1">
        <location>
            <begin position="46"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC95234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="362" mass="38781" checksum="986AEDF1F67F0A5D" modified="2018-07-18" version="1">MCVLHQTSIGFSRSRYYTGSTQQVRLDIFYRKEAEMNKAIRIAQTGGPEVMQLMDVAIGTPGAGEVCIQHKACGLNFIDVYHRTGLYKQLLPTGLGVEGAGIVEAVGPDVHHVKVGDRVAYAGGPPGAYAQRRIMPASVLVKLPDSISFDVAAAVMLQGLTVQYLFCRTYKIQSGQTILFHAAAGGVGLLACQWAKALGVTMIGTVGSAAKAALAKANGCAHVINYNEENFVERVEEITAGRGVSVVYDSIGKDTFFGSLDCLSPLGTMVSFGNASGPVPDFNLSELASRGSLFITRPSMMHYTAVRSDLEQMAAELFAMIETKKLIVHINQRYALADVGKAHRELEARKTTGCSILIPDAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5J4</accession>
    <name>A0A2S9H5J4_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Cell division protein FtsL</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ftsL</name>
        <name evidence="7" type="ORF">S2091_0406</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Part of a complex composed of FtsB, FtsL and FtsQ.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell inner membrane</location>
            <topology evidence="6">Single-pass type II membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
        <text evidence="6">Localizes to the division septum where it forms a ring structure.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the FtsL family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95211">
        <property type="protein sequence ID" value="PRC95211"/>
        <property type="gene ID" value="S2091_0406"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032153">
        <property type="term" value="C:cell division site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043093">
        <property type="term" value="P:FtsZ-dependent cytokinesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00910">
        <property type="entry name" value="FtsL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011922">
        <property type="entry name" value="Cell_div_FtsL"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37479">
        <property type="entry name" value="PTHR37479"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04999">
        <property type="entry name" value="FtsL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02209">
        <property type="entry name" value="ftsL_broad"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="6 7" id="KW-0132">Cell division</keyword>
    <keyword evidence="6" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="2 6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC95211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="93" mass="10677" checksum="95F4386531F35570" modified="2018-07-18" version="1">MSGRLNVVLLLALMVCALILVRTQYQARHLFIELERSQTEARQLDVEWSQLQLDQSGLGKHERIQASAIKDLNMVPVTPDRTQYITVDSKQTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSF2</accession>
    <name>A0A2S9GSF2_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">ATP synthase subunit c</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">ATP synthase F(0) sector subunit c</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">F-type ATPase subunit c</fullName>
            <shortName evidence="13">F-ATPase subunit c</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Lipid-binding protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">atpE</name>
        <name evidence="15" type="ORF">S2091_4649</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12 13">F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.</text>
    </comment>
    <comment type="function">
        <text evidence="13">Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="13">Cell membrane</location>
            <topology evidence="13">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the ATPase C chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000041">
        <property type="protein sequence ID" value="PRC90641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90641">
        <property type="protein sequence ID" value="PRC90641"/>
        <property type="gene ID" value="S2091_4649"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045263">
        <property type="term" value="C:proton-transporting ATP synthase complex, coupling factor F(o)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01396">
        <property type="entry name" value="ATP_synth_c_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005953">
        <property type="entry name" value="ATP_synth_csu_bac/chlpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000454">
        <property type="entry name" value="ATP_synth_F0_csu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020537">
        <property type="entry name" value="ATP_synth_F0_csu_DDCD_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038662">
        <property type="entry name" value="ATP_synth_F0_csu_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002379">
        <property type="entry name" value="ATPase_proteolipid_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035921">
        <property type="entry name" value="F/V-ATP_Csub_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00137">
        <property type="entry name" value="ATP-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00124">
        <property type="entry name" value="ATPASEC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81333">
        <property type="entry name" value="SSF81333"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01260">
        <property type="entry name" value="ATP_synt_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00605">
        <property type="entry name" value="ATPASE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 13" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="13" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 13" id="KW-0138">CF(0)</keyword>
    <keyword evidence="6 13" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="8 13" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 13" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="10 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 13" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="6"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="51"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-synt_C" evidence="14">
        <location>
            <begin position="9"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="site" description="Reversibly protonated during proton transport" evidence="13">
        <location>
            <position position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00025198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="PRC90641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="80" mass="8340" checksum="70599696165F6A4B" modified="2018-07-18" version="1">MTDYSFVALACGLIIGLGAIGACIGIALMGGKFLEASARQPELMNQLQTKMFLLAGLIDAAFLIGVGIAMMFAFANPFHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSI8</accession>
    <name>A0A2S9GSI8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acetyltransferase (GNAT) family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4577</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000038">
        <property type="protein sequence ID" value="PRC90684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90684">
        <property type="protein sequence ID" value="PRC90684"/>
        <property type="gene ID" value="S2091_4577"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="84" mass="9354" checksum="1EFB205A2641BDC1" modified="2018-07-18" version="1">MGEESYGEIKRVFVMDSHRGKGISKRIMSHLEKHLVMLGVPVARLETGVKQPEALKSLGYVACAPFGGYALDPFSMFMDKRLLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSJ3</accession>
    <name>A0A2S9GSJ3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4616</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000039">
        <property type="protein sequence ID" value="PRC90666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90666">
        <property type="protein sequence ID" value="PRC90666"/>
        <property type="gene ID" value="S2091_4616"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021333">
        <property type="entry name" value="DUF2946"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11162">
        <property type="entry name" value="DUF2946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC90666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="134" mass="14797" checksum="20A7C8714B1F4DF7" modified="2018-07-18" version="1">MFWHTSHHSNAKKYTNWLASLVICALLWQALVPSIAFARSELNPRLWDEICSAYGNRSTTDLSKIGQSAPTNTTHHADCPLCLSSFTDIILGTPLATPEFHLLTVSEISYIASSTSYSITRLVGPEARGPPFFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSR8</accession>
    <name>A0A2S9GSR8_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HTH cro/C1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4512</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000036">
        <property type="protein sequence ID" value="PRC90764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90764">
        <property type="protein sequence ID" value="PRC90764"/>
        <property type="gene ID" value="S2091_4512"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013096">
        <property type="entry name" value="Cupin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07883">
        <property type="entry name" value="Cupin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="20"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="194" mass="21037" checksum="94C9898B66F298F5" modified="2018-07-18" version="1">MPKSINKPAANTPPEVGATLQRMRLERGLTLEDLSRTAGVSKSMLSQIEREKANPTIAVAWRLANALGVDIAELLSSEIKKVDAIRILEAHETPTLPGEHAGYILRILGPMELAGKFEWYELTLAPNGALVSGSHDPGTKEHLTLLHGSVELEVNSVKRKLKVGATARYAADLPHAIYNVGKSEAKAIMVVIHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GST7</accession>
    <name>A0A2S9GST7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative integral membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4504</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000036">
        <property type="protein sequence ID" value="PRC90756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90756">
        <property type="protein sequence ID" value="PRC90756"/>
        <property type="gene ID" value="S2091_4504"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018729">
        <property type="entry name" value="DUF2269_transmembrane"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10027">
        <property type="entry name" value="DUF2269"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="82"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="132"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="156" mass="17874" checksum="B5D98699353ACCD4" modified="2018-07-18" version="1">MNSYLVLKWLHILSATILFGTGIGIAFFKWITDRSGDVRAIRIINERTVLADWLFTTPAVILQPATGLGLVYMAGYPLFSGWVFYAIILYLIAGACWLPVLWLQIRMRELARTADAENTPLPARYWQYAQRWFWLGVPAFVALIAVYWLMVFKPAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSZ6</accession>
    <name>A0A2S9GSZ6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NHL repeat</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_4420</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000034">
        <property type="protein sequence ID" value="PRC90839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90839">
        <property type="protein sequence ID" value="PRC90839"/>
        <property type="gene ID" value="S2091_4420"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001258">
        <property type="entry name" value="NHL_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01436">
        <property type="entry name" value="NHL"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51125">
        <property type="entry name" value="NHL"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015747114" evidence="3">
        <location>
            <begin position="26"/>
            <end position="724"/>
        </location>
    </feature>
    <feature type="repeat" description="NHL" evidence="2">
        <location>
            <begin position="151"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="repeat" description="NHL" evidence="2">
        <location>
            <begin position="194"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC90839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="724" mass="76529" checksum="BF4AC6F0529D7F51" modified="2018-07-18" version="1">MSAKLIQLSKFFVISFLTIAIGVHASASSWGDENSTSTIQINSLNVNEDNSAIANPKPDSTTNGMLSLIAGNSNGPGFADGSLNDAQFGYATYGMVEIFKGIASDSHGNLYVADTSNHTIRKIDAKGIVTTLAGQVRNPGNEDGPGAQARFNLPTGITIDTHGNLYVTDAGNFTIRKITPAGVVSTLAGQVGVQGYTDGEGMSAKFRLPKGIAVNKSGDIFVVDTGNSTIRKISSDGIVSTFAGINRKFGFVNGDGINALFASPIDITIDRYGVMYVTDSGNKAIRRITPNGTVSTLTGTYTTSEDNDGTLSTAHFSYPQGIGVDHEGNLYISDSHRIRKVSINGYVTTLAGQDAGGSNDGKGTLASFSIPGGITVSRDGSLYVADNFLVRKVNATGLVTTYAGQKIISGSEDGIADHASFNTPNQMAVDKAGNVYVIDRGNALVRKIESNGKTTTLVSYRHSDWPVIKNLPKATFSSIAGLDIDHSYLAGIAVDQSNNVYISDAGNFVILKISSNGQVTVMAGIAGQRGSNDGAAMDAHFTQPANMVFDKLGNLFVVDAGSIRKIDQSGKVATFVGNINNRGDRIDETGQAAQFARIDGITIDQGGNLYVIDNHTLREISSQGVVSTFDDLSEKNSFFNGFQTTNFPASLAIDGDENIFYAIGTVVKRRSKEGQLSEVAGGEVSYEVKPGLHRVLEDISCVVMIDSKTFAILSGNAVFKLYLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GT42</accession>
    <name>A0A2S9GT42_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4439</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000034">
        <property type="protein sequence ID" value="PRC90858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90858">
        <property type="protein sequence ID" value="PRC90858"/>
        <property type="gene ID" value="S2091_4439"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC90858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="157" mass="17549" checksum="7CF786F4BCE8C78E" modified="2018-07-18" version="1">MHLRVLTFVSAMFIAYVLSDVAIAEEIVSRYGKISAVELPNKSGSYSIGLDDKSITTVDALAVSLYRVTPSKNEKVENIIVEKVLPGLNCHNEYLLVTISQDRKSIFSPSFGKCMELDGVENLNERVTIRLHSTEINTNNKLRIDSYVWANGKLNKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GT51</accession>
    <name>A0A2S9GT51_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF4375 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4378</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000033">
        <property type="protein sequence ID" value="PRC90885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90885">
        <property type="protein sequence ID" value="PRC90885"/>
        <property type="gene ID" value="S2091_4378"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025402">
        <property type="entry name" value="DUF4375"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14300">
        <property type="entry name" value="DUF4375"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4375" evidence="1">
        <location>
            <begin position="28"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="150" mass="16929" checksum="05FA733490BCDBD5" modified="2018-07-18" version="1">MKSFDFLESASKISFAKLDKAGGNIQLMKDPLQTIAIVYSAQGIIDNGGLEYFFSSDFPENPPYQMFIDAYNKIGAFEEAEGIKKSLAFFEDPNPELNLESRLKFIDSLPSDFSHQFSKISEQMLGSESVWFLLNQYAELNQNLIDSSNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTA3</accession>
    <name>A0A2S9GTA3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">N-acyl amino acid synthase, PEP-CTERM/exosortase system-associated</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4348</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000032">
        <property type="protein sequence ID" value="PRC90947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90947">
        <property type="protein sequence ID" value="PRC90947"/>
        <property type="gene ID" value="S2091_4348"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022484">
        <property type="entry name" value="PEP-CTERM/exosrtase_acylTfrase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03694">
        <property type="entry name" value="exosort_acyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC90947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="269" mass="31720" checksum="ADD8048CEEEDE988" modified="2018-07-18" version="1">MLIEILLGKRDLLIPYFMFNKVLRGNMESTVLQEIYKLRYEVYCLECKYLTADDFQEEMETDNYDESSTHFAAYNLDQSIVGTVRLVQPHDEQEYPFESHCGVFDGFEFPDRKMCGEISRLVVRKTYRRRRGDSMEGVSKDFVEEGSVASIKPNPESHQRSTNSPLLLLGMYREMYRHSRQNNIRYWYAAMERSLARSLEKMGFKFIPIGPQTDYYGQVTPHIVDLEELNVRLRRENRFLAAWFNDEPIPIWIMVKTLVGSMKSQAKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTG6</accession>
    <name>A0A2S9GTG6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative conserved protein related to C-terminal domain of eukaryotic chaperone SACSIN</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4282</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000031">
        <property type="protein sequence ID" value="PRC90986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90986">
        <property type="protein sequence ID" value="PRC90986"/>
        <property type="gene ID" value="S2091_4282"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007842">
        <property type="entry name" value="HEPN_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05168">
        <property type="entry name" value="HEPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HEPN" evidence="1">
        <location>
            <begin position="8"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="133" mass="14415" checksum="AF75A58D184CC55E" modified="2018-07-18" version="1">MSIISPHDLILKANRAIESAQLLRHAGDVDGACNRAYYAMFDAAKAGLLKSVPGIDPTIGKTHSGLISAFGQHLVKTGLVPVEFGRAFNRAHDIRQVADYTGDLIEIAQVESLIQQAIEFVEWISSQIVSKSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTK5</accession>
    <name>A0A2S9GTK5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_4231</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000030">
        <property type="protein sequence ID" value="PRC91043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91043">
        <property type="protein sequence ID" value="PRC91043"/>
        <property type="gene ID" value="S2091_4231"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="27"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="157"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC91043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="224" mass="24637" checksum="04B79FA21ABF5E1B" modified="2018-07-18" version="1">MLDKCHGNQEENENSLQQCMDKKASMNILLADDHTIFRHGLKLLLDSQCGYQVVAEAASLDVVSSLLQQHPIDLMILDYNMPGGDSTAVLSYCKHRYADLKVIALTGSESGIVLKQLQDASADAVLRKDVSGSELLLCITKVMAGQVVVSADVQERIAESITNLTPRELQTVNMINDGLTNTDMAKRLNLSAKTIDKHRENLMRKLQVSNIAQLIHKAKLLGLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTK7</accession>
    <name>A0A2S9GTK7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4233</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000030">
        <property type="protein sequence ID" value="PRC91045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91045">
        <property type="protein sequence ID" value="PRC91045"/>
        <property type="gene ID" value="S2091_4233"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="55" mass="6337" checksum="C278DCAB9AEC1DA0" modified="2018-07-18" version="1">MKAPFQERMLIMFKKQDPYSFTQYVLLYGVINGTQEAIGTLATEYRVALYNDVLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTL3</accession>
    <name>A0A2S9GTL3_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF2090 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4245</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000030">
        <property type="protein sequence ID" value="PRC91057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91057">
        <property type="protein sequence ID" value="PRC91057"/>
        <property type="gene ID" value="S2091_4245"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018659">
        <property type="entry name" value="DUF2090"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09863">
        <property type="entry name" value="DUF2090"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF2090" evidence="1">
        <location>
            <begin position="7"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="322" mass="36429" checksum="E490A4A94E1B0F27" modified="2018-07-18" version="1">MKPGYIKPLYLLPFDHRDSYVRDMFHFQLPLSNEQHKKIVASKQLIYEGFLAALDSDELKSRAGILVDEQFGTEILQNAIKRTCIRAISVEKSGTDEFEFEYGKAFPAHIDLFKPTFAKVLVRYNPEGDAALNLRQVARLLKLSEYCQSTQRPLMFELLVPATKAQLSWYNEDKNAYDRKCRPMLMVQAICALQDAGIEPSIWKVEGLDSRENCEKVVDAARRHGRNEVSCIILGRGADEKKVAEWLAIAAPVPGFIGFAVGRTTFWDAIAEFESKTISREVAIAHIAQRYRMWVDIFENAHSVKNGQPKKLSNATSAKALA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTP9</accession>
    <name>A0A2S9GTP9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4198</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000029">
        <property type="protein sequence ID" value="PRC91102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91102">
        <property type="protein sequence ID" value="PRC91102"/>
        <property type="gene ID" value="S2091_4198"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015785065" evidence="1">
        <location>
            <begin position="28"/>
            <end position="845"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="845" mass="91783" checksum="7233A9902DDB5BEB" modified="2018-07-18" version="1">MMKITLNKLLPIFLLLSTLFFEQFASAAPASPPPENISHLGPTITANVVRGKESLPIFLVNHLRKGDKLVVTTDQAEKTDVKWLAVLATVTPISNNVVTRQFDLSDHAGEVAIEIAADDQIPIIVLAPQVRTMFGLHTSFSESAALISDAIKTDPQRFVDLQKIDQINHAIAFISRALDAVIQTKKSDQAVDAAKSLAAKFGVKYVDPDCFKDGTVNSKCVAAYIVASEDLLVPSNDIWLAAGPDAASVKLPTDIFAGLKLVTETSTYLVNKYGDNYDFAPSLGQRKAATTTIQLFTNARFKSGDIKTAYVYVPSWFPGKAPELVLESKTPFCLAKGDIVSSVKGRLPLLNYWHDWNLVIKEHGSSAMLAQFNVIDFKPDTGHFLFDYKNTDSALTLHGQLLDATLTAKFGFAEVSLSPFNFVVPTNAPLLAQIVGLDSLISGEQTKLGFTGVNGNACIEQVNLLVNGKTLASSTAELPNELSVDLSKAEPGPATLEVQQYGAAKQELVVTIQQRRAHIQRLVHYDLETELSVYGDNLDRIEVIQLGNNLLCRASDVPNLTLNASPVSSTSRIFSCPADVAANAKFPAKVTIRHLEKEPASFDVAVTKIEARPHMTVAPLNATVATLSSKALQWNLSADDQFITEDSGISILMHAFGGYKLSHGSYVLQLKFGDGAENEVANNPQADNAVISVPMMSDLAHNELRTRSPISFAKIQLPSIVNPIWYRIKHQPSGLAGDWQALNRSIVFFPQIDALTCDTDGRGLLIHGPQLELIDWMSNDLISSGNVQPAADTKTVQARCDKDLCLAINGLGAANKLKVKVHWIDERLFEVTFPAAPTCAPQVQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTX0</accession>
    <name>A0A2S9GTX0_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">AMP nucleosidase</fullName>
            <ecNumber evidence="2">3.2.2.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">AMP nucleosidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_4072</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>AMP + H2O = adenine + D-ribose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:20129"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16708"/>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="3.2.2.4"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.2.4" evidence="2"/>
    <dbReference type="EMBL" id="PUGF01000027">
        <property type="protein sequence ID" value="PRC91177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91177">
        <property type="protein sequence ID" value="PRC91177"/>
        <property type="gene ID" value="S2091_4072"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008714">
        <property type="term" value="F:AMP nucleosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1850.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021826">
        <property type="entry name" value="DUF3412"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031100">
        <property type="entry name" value="LOG_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037153">
        <property type="entry name" value="YgdH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027820">
        <property type="entry name" value="YgdH_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11892">
        <property type="entry name" value="DUF3412"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14793">
        <property type="entry name" value="DUF4478"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03641">
        <property type="entry name" value="Lysine_decarbox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4478" evidence="5">
        <location>
            <begin position="9"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="DUF3412" evidence="4">
        <location>
            <begin position="336"/>
            <end position="455"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00031983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF11892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF14793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC91177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="456" mass="50061" checksum="BB9920C99BD6E211" modified="2018-07-18" version="1">MEYPVLDTQISPEGRLDVLLKAEVNKLLDTSHGGLYTIFRHCTLAVLNSGNALDDGKELLARYPSFSISIIHRERGIKLDIKNAPASAFVDGVMIKGIQEHVFAVLRDIIFLNSEIEGNAQFDITTSQGITDAVFHILRNANQLHPLVNPNLVVCWGGHAISGNEYDYTKHVGYQLGLRGLNICTGCGPGAMKGPMKGATIGHAKQRIANGRYLGVTEPGIIAAEAPNAIVNELVILPDIEKRLEAFVRLGHAIVIFPGGAGTTEEILYILGILLHPDNVDTPFPLIFTGPASAAGYFKLIDQFIGATLGAQAQNRYQIIIDNPVLVAQQVLAGIGEVRAYRKATSDAYYFNWALKIPNEFQHPFIPNHLNMRQLQLHKNQDTHLLAANLRRAFSGIVAGNVKEAGIRAIEEFGHFELTGDSDLMESIDALLTSFVQQQRMKLPGKLYVPCYRIIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTY7</accession>
    <name>A0A2S9GTY7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_4087</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000027">
        <property type="protein sequence ID" value="PRC91192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91192">
        <property type="protein sequence ID" value="PRC91192"/>
        <property type="gene ID" value="S2091_4087"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015399498" evidence="3">
        <location>
            <begin position="33"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="125"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="72"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC91192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="164" mass="19031" checksum="05513E12695C561E" modified="2018-07-18" version="1">MRKENVTRQFSFHIVFTSAALTLLLSSNAAYAIHKCILNGSITYSDMPCPANANVLPFTPSISPPNDPAAAKQRYLSDLQQLKKIEQQKEKEETQQKREALILINENKQARDKKFKCKDLDLKRKIAKQQRDKPQSKRKNKNNEQTEIRVQQAENNYQYFCKTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GU23</accession>
    <name>A0A2S9GU23_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Bacterial regulatory protein, tetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_4103</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000027">
        <property type="protein sequence ID" value="PRC91208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91208">
        <property type="protein sequence ID" value="PRC91208"/>
        <property type="gene ID" value="S2091_4103"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011075">
        <property type="entry name" value="TetR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16925">
        <property type="entry name" value="TetR_C_13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="8"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="31"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="196" mass="21547" checksum="2B4C8438CDE4947C" modified="2018-07-18" version="1">MEKTVHFQDTKQRILAVGESLIVGRGFSALGLSEILTTAKVPKGSFYHYFQSKEGFGVALLERYFSEYDERLTILFADQTMTMRERVMSYFKGWHATSAEHACNSTCLVVKLAAEVSDLSEPMRCALALGMSRITGQLAAALSLAQAEGSVSMQMDAAQLAEILYSMWVGASLVAKVKHDLLPLDLALQQTELLVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GU46</accession>
    <name>A0A2S9GU46_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4014</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000026">
        <property type="protein sequence ID" value="PRC91229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91229">
        <property type="protein sequence ID" value="PRC91229"/>
        <property type="gene ID" value="S2091_4014"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025570">
        <property type="entry name" value="DUF4337"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14235">
        <property type="entry name" value="DUF4337"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="168"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="188" mass="20775" checksum="100AC28A2D77FC5B" modified="2018-07-18" version="1">MPEEFEVHGPHDHELEHAAHGGDDFSSKIAVMTAIMATTGAIFGFQAGSTQNDAAMFKNKAAIVKTEASDQWNFYQAKSNKQNFAELAVTMPGVDVAKYQSDIARYKVEKEGIKKHAEELDKSSLEWEDKSTEILHQHHRWAQAMTALQIAISLAAITLLTRKKWLQIGSYGVAGIGIILAGCAWFQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GU78</accession>
    <name>A0A2S9GU78_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_4048</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000026">
        <property type="protein sequence ID" value="PRC91263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91263">
        <property type="protein sequence ID" value="PRC91263"/>
        <property type="gene ID" value="S2091_4048"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015562">
        <property type="term" value="F:efflux transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003423">
        <property type="entry name" value="OMP_efflux"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010131">
        <property type="entry name" value="RND_efflux_OM_lipoprot_NodT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02321">
        <property type="entry name" value="OEP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01845">
        <property type="entry name" value="outer_NodT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0564">Palmitate</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1134">Transmembrane beta strand</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015372017" evidence="2">
        <location>
            <begin position="23"/>
            <end position="475"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU362097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="475" mass="51404" checksum="65086C7AEBBD6D5E" modified="2018-07-18" version="1">MFKRTWTLSILSVFAAALSACAVGPDYHQPKVEVPDTQAQSKQTAVASNWWRQFNDPVLNQLIDTGLQHNQDLIAAAARVEAAAAQAGIARSNLRPALDAGVGAQKGRTSQQINASDTPLVSDTRYGNLSVSWELDLWGKLRRSNEAANADFMANRFNRDAVALSLTAQLAQTYFQLRAFDAQLDIARRTLQSREESLALQTKRFKGGIISELDQRQAEAEAASARAVIPQIARSLEQTESALGVLLGHSPKQLVEGKLLRGQDINNLTLPLDIPAVLPSILLERRPDIAASEQLLIAANARIGAAKAAYFPSINLSGAFGSQSPSLDSLFTGPTRTWNFASNLAAPIFNFGATGYAVDAASANQKQALAQYQKSVQNAFKDALDAFNANSTARQIQAAQTTQLAALNKTLHLSSLRYDNGYSNYLDVLDAQRNSFQAELNLISAQLDRLNSTISVYKALGGGWESDTEEVAEAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUD8</accession>
    <name>A0A2S9GUD8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3897</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000024">
        <property type="protein sequence ID" value="PRC91352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91352">
        <property type="protein sequence ID" value="PRC91352"/>
        <property type="gene ID" value="S2091_3897"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="132" mass="14528" checksum="F9C1CC7DCDFEB806" modified="2018-07-18" version="1">MLLCFCNSLASAKDIPRYGIFVYSDFCTSSISGDLYGNRITLRRLIDGDTLIYEYTDGSTHVVVADNLMLDPKSGKINFEVHAQENLNAIVSGQFSNDGGSLTAHGMLFNEMATVTLKLTMNFSTPIKNCKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUQ7</accession>
    <name>A0A2S9GUQ7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3856</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000023">
        <property type="protein sequence ID" value="PRC91441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91441">
        <property type="protein sequence ID" value="PRC91441"/>
        <property type="gene ID" value="S2091_3856"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="54" mass="6047" checksum="941D5226E050C922" modified="2018-07-18" version="1">MVVSLVGGNLVSIIGFVCRHTQALTGAHQYGARGKTLVADSNWHKNWKKRVFFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUR9</accession>
    <name>A0A2S9GUR9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Type II secretory pathway component PulF</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_3941</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GSP F family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000024">
        <property type="protein sequence ID" value="PRC91396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91396">
        <property type="protein sequence ID" value="PRC91396"/>
        <property type="gene ID" value="S2091_3941"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.81.30">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003004">
        <property type="entry name" value="GspF/PilC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018076">
        <property type="entry name" value="T2SS_GspF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042094">
        <property type="entry name" value="T2SS_GspF_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30012">
        <property type="entry name" value="PTHR30012"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00482">
        <property type="entry name" value="T2SSF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00812">
        <property type="entry name" value="BCTERIALGSPF"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="174"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="227"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="381"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="domain" description="T2SSF" evidence="8">
        <location>
            <begin position="74"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="domain" description="T2SSF" evidence="8">
        <location>
            <begin position="278"/>
            <end position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC91396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="409" mass="44462" checksum="B25FF1C39D0F783D" modified="2018-07-18" version="1">MATAQNKASSTVKDFVFSWEGRDKTGKSVRGEMRASGATIVSATMRRQGILVTKVKKKSFATGKKVTEKDIALFTRQLATMMKAGVPLLQSFDIVGKGHSNPSVSKLILDIRGDVETGTSLSQAFRKFPLYFDPLFCNLVGAGEQAGILEDLLTRLAIYKEKTVAIKAKIKGALFYPVSIIAVAFVVTSVIMIWVVPAFKDVFKSFGADLPAPTLVVMGISEFFVKYWYLIFGVTFGGLYLFFQAWQRSLEVQRMMDRLLLKLPIFGEIIRKATIARWTRTLATMFAAGVPLVESLDSVGGAAGNAVYLDATLKIQTEVSSGTSLTIAMQNANVFPNMVTQMVSIGEESGSLDAMLGKVADFYEEEVDEAVASISSLMEPIIMVFLGVIIGALVIAMYLPIFKLGAVVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GV44</accession>
    <name>A0A2S9GV44_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Xanthine and CO dehydrogenases maturation factor XdhC/CoxF family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3699</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000021">
        <property type="protein sequence ID" value="PRC91583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91583">
        <property type="protein sequence ID" value="PRC91583"/>
        <property type="gene ID" value="S2091_3699"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003777">
        <property type="entry name" value="XdhC_CoxI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027051">
        <property type="entry name" value="XdhC_Rossmann_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13478">
        <property type="entry name" value="XdhC_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02625">
        <property type="entry name" value="XdhC_CoxI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="XdhC_CoxI" evidence="1">
        <location>
            <begin position="15"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="domain" description="XdhC_C" evidence="2">
        <location>
            <begin position="166"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02625"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="323" mass="35080" checksum="59514E4369BCB417" modified="2018-07-18" version="1">MECLDLDVLQTALTWREAGFDVSLATVVQTWGSAPRPPGSLLAIRSDGQVLGSVSGGCIEDDLIARVRNQGMPEKPEWVQYGVTRAQAQHFGLPCGGILELVLEPVTDSSWIAEVLQRTSMHELVQRTLVLASGAIMLSPGQPQSSQSLFFDGEKLTMVFGPQLRLLMIGAGQLSQIVAQMAQPLGFDVLMCDPREEYTGTWQPAWGRHIAGMPDDVVLQIKPDAHTAIVALTHDPKLDDMALLEALKSAAFYVGALGSRANNKKRRERLALFDLSDEQIEHLHGPIGLHIGSRTPAEIAISILAEIISVKNGVIPSQKKLID</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GV79</accession>
    <name>A0A2S9GV79_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_3573</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000020">
        <property type="protein sequence ID" value="PRC91635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91635">
        <property type="protein sequence ID" value="PRC91635"/>
        <property type="gene ID" value="S2091_3573"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010559">
        <property type="entry name" value="Sig_transdc_His_kin_internal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06580">
        <property type="entry name" value="His_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="34"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="178"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="4">
        <location>
            <begin position="326"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="94"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="202"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="113"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC91635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="422" mass="46733" checksum="FAA9D3FA6E5F0FF6" modified="2018-07-18" version="1">MNQPTLILVKEFIDSLISMLTRFFEKVTNWVTELSWMKFVLFAIVLMIMGAITQDQILSSDEKVIVTKKPHSASSKIFSDRDSDIEINNSGIHIRKNKNSIPPAPPAPPTISTTPADSVDSSNTTPSNSNAKEPIDDDEIHVKLPPGVSDDISKVINDEIADANEHEVESYRKKQSTWLMSLIMLSLFGLFGIKALMGGKRRAEILAQAAQEAAERESLRRQVVEAKMQMMQAQIEPHFLFNTLASVEHLIETDPPRASAMQRSLIQYLRAVIPQMRENSNGTNLGREAGIVQEYLTLLKMRMEERLEFSISIPEGLSSAAFPSMMLQTLVENAIKHGLEPKAEGGKVTISAEVAHNKLRVSVSDNGLGFGAVPSNGTGLGLQNIRERLALLYQGNYQFIITPNSPTGVAVTIEIPYQFTHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVC5</accession>
    <name>A0A2S9GVC5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_3732</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPF0410 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000021">
        <property type="protein sequence ID" value="PRC91616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91616">
        <property type="protein sequence ID" value="PRC91616"/>
        <property type="gene ID" value="S2091_3732"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007341">
        <property type="entry name" value="Transgly_assoc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33884">
        <property type="entry name" value="PTHR33884"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04226">
        <property type="entry name" value="Transgly_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="27"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="59"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC91616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="81" mass="8392" checksum="6E9C6065BAB012C1" modified="2018-07-18" version="1">MHLIWTILIGFVAGILAKMILPGNNPGGFIMTVLLGIGGSIAATYLGHFIGWYHAGESAGFVGAVVGAIVLLGIYHLATKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVL0</accession>
    <name>A0A2S9GVL0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3505</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000019">
        <property type="protein sequence ID" value="PRC91750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91750">
        <property type="protein sequence ID" value="PRC91750"/>
        <property type="gene ID" value="S2091_3505"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="23"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="85"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="116"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="141" mass="16061" checksum="19385FDE5A9FA4C5" modified="2018-07-18" version="1">MPNRPSTVFIFPSIKLEKFGSPLVQWILIFILSLAFASGAITGYFEARHALEPLWSDYATNILLIILTLSWYHVDSNDRRYDRNIWLNMLILGLAIIGIPFYLIRSRVQGKKLAAIGWLIVFTCLFTSLNLLGTALMGWLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVL5</accession>
    <name>A0A2S9GVL5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3518</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000019">
        <property type="protein sequence ID" value="PRC91763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91763">
        <property type="protein sequence ID" value="PRC91763"/>
        <property type="gene ID" value="S2091_3518"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009783">
        <property type="entry name" value="DUF1348"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31757">
        <property type="entry name" value="PTHR31757"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07080">
        <property type="entry name" value="DUF1348"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="156" mass="18705" checksum="50DA3A9ABADDE25B" modified="2018-07-18" version="1">MMTIKLPVPPFTKATAIQKVRLAEDAWNTRDPDKVVFVYTEDTRWRNRTDFPVGREQVHQFLTRKWGRELEYRLIKELWAYGGNRIAVRFAYEYHNDAGQWFRAYGNENWEFNAEGYMTHRHASINDLPISESERKFFWPIGRRPDEHPELSELAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVN2</accession>
    <name>A0A2S9GVN2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Bacterial extracellular solute-binding protein, family 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_3540</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000019">
        <property type="protein sequence ID" value="PRC91785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91785">
        <property type="protein sequence ID" value="PRC91785"/>
        <property type="gene ID" value="S2091_3540"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001638">
        <property type="entry name" value="Solute-binding_3/MltF_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00497">
        <property type="entry name" value="SBP_bac_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00062">
        <property type="entry name" value="PBPb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015658772" evidence="2">
        <location>
            <begin position="20"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="domain" description="PBPb" evidence="3">
        <location>
            <begin position="21"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC91785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="252" mass="27971" checksum="42EBFCAB6C74313F" modified="2018-07-18" version="1">MKLITFAILLVTASNLALSQPLPMVVDIIQSEPLGFQSKNGTPTGLHFDILTALSKLTGVPIKINIVPKARLIYDLKNGIADGAILFPNPEVDAITIDSGVTDQTKLVALGKVGFPLKSYDDLVRAKTVLMLVNTTFGNPFDSDLRLDKDKANSYDQMVTMFIHDRANVITGNLMALLYLLKKVNSVSKVDTSGLLFRNLDNHFYIAKKSHYREKSKVFINALDEMMNDGTINNIAMKYFDDHDAKLNLSEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVN4</accession>
    <name>A0A2S9GVN4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_3525</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000019">
        <property type="protein sequence ID" value="PRC91770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91770">
        <property type="protein sequence ID" value="PRC91770"/>
        <property type="gene ID" value="S2091_3525"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="6"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="5">
        <location>
            <begin position="137"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="137"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC91770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="246" mass="27964" checksum="B53BCCAF6D9AE202" modified="2018-07-18" version="1">MEQVDHILIVDDDADIRELLGQYLEKNGFKVSAAANGRQMRQILAVSTIDVIVLDLMLPGEDGLALCRDLQVGRATPIPILMLTARNEEADRILGLEMGADDYLTKPFASRELLARVRAILRRSRMLPHDLHPTETAHVLAFGTWQLDTSVRHLFDSSNTLVSLSVAEYRLLRVFLDHSRRVLTRDQLLNLTQGRDAELFDRSIDILVSRLRQRLRDDPREPVYIKTVRNEGYVFSVPVEIRVAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVN6</accession>
    <name>A0A2S9GVN6_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6">Carbonic anhydrase</fullName>
            <ecNumber evidence="3 6">4.2.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Carbonate dehydratase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_3542</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Reversible hydration of carbon dioxide.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>H(+) + hydrogencarbonate = CO2 + H2O</text>
            <dbReference type="Rhea" id="RHEA:10748"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="EC" id="4.2.1.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the beta-class carbonic anhydrase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.1" evidence="3 6"/>
    <dbReference type="EMBL" id="PUGF01000019">
        <property type="protein sequence ID" value="PRC91787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91787">
        <property type="protein sequence ID" value="PRC91787"/>
        <property type="gene ID" value="S2091_3542"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004089">
        <property type="term" value="F:carbonate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015976">
        <property type="term" value="P:carbon utilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00884">
        <property type="entry name" value="beta_CA_cladeB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045066">
        <property type="entry name" value="Beta_CA_cladeB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001765">
        <property type="entry name" value="Carbonic_anhydrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015892">
        <property type="entry name" value="Carbonic_anhydrase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036874">
        <property type="entry name" value="Carbonic_anhydrase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11002">
        <property type="entry name" value="PTHR11002"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00484">
        <property type="entry name" value="Pro_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00947">
        <property type="entry name" value="Pro_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53056">
        <property type="entry name" value="SSF53056"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00704">
        <property type="entry name" value="PROK_CO2_ANHYDRASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00705">
        <property type="entry name" value="PROK_CO2_ANHYDRASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC91787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="220" mass="23556" checksum="E9D16441DBAA6791" modified="2018-07-18" version="1">MKSIVEGVLKFQQNAFPQLSTLFKELATTQNPTALFITCSDSRVVPELLTQQNPGDIFVIRNAGNIVPSYSSEPGGVTATVEYAVAVLGVTDIVICGHSDCGAMTAISSCKCLDHLPAVASWLRHADSAKVVNASRTHISDAVRLSSMVRENVIAQLVNIKTHPSVALALEQGRLNLHGWVYDIETGSIVALDGETNRFVSLAEFPQTVATHSKRSALVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GW86</accession>
    <name>A0A2S9GW86_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Sarcosine oxidase gamma subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3313</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000017">
        <property type="protein sequence ID" value="PRC91971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91971">
        <property type="protein sequence ID" value="PRC91971"/>
        <property type="gene ID" value="S2091_3313"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007375">
        <property type="entry name" value="SoxG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027266">
        <property type="entry name" value="TrmE/GcvT_dom1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04268">
        <property type="entry name" value="SoxG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="229" mass="25002" checksum="11ACFD4D3A56B762" modified="2018-07-18" version="1">MSNYSPEIAAEAVKQINPNFKPYARSPLHAFGLPAQARSKDSSRGVWMNELPLLGYIVVRGNSADPLFIQAIQDVLGIALPTTPSTFVPVNQGIVVWQTPDEWLVVCARAAHGNYLAKLTESLSTLHAQVADNSGGLTTVYVSGAKHVELLRHVGVYDFESITDGQAISTICHKANIVALRHDSEGIFVIFRRSFADYFWLLLTKAARPYGLGISVLTPDSSHPLLSFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWC1</accession>
    <name>A0A2S9GWC1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Heavy metal efflux pump, CzcA family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_3298</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000017">
        <property type="protein sequence ID" value="PRC91956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91956">
        <property type="protein sequence ID" value="PRC91956"/>
        <property type="gene ID" value="S2091_3298"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2090.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027463">
        <property type="entry name" value="AcrB_DN_DC_subdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001036">
        <property type="entry name" value="Acrflvin-R"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004763">
        <property type="entry name" value="CzcA/CusA/SilA/NccA/HelA/CnrA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32063">
        <property type="entry name" value="PTHR32063"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00873">
        <property type="entry name" value="ACR_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00702">
        <property type="entry name" value="ACRIFLAVINRP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82714">
        <property type="entry name" value="SSF82714"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00914">
        <property type="entry name" value="2A0601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="335"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="361"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="387"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="454"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="486"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="531"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="886"/>
            <end position="903"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="910"/>
            <end position="930"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="936"/>
            <end position="960"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="981"/>
            <end position="1001"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="1013"/>
            <end position="1039"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC91956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="1062" mass="114906" checksum="0E7AC67A1089EC64" modified="2018-07-18" version="1">MNSIVAFSLKQRLLVVILLVALFALGTVGFIKLNIEAYPDPVPPLVDIITQSTGQSAEEIERYVTIPIEVQLAGIPHVTTVRTISLFGLSDVKVQFTYDYSYQEAEQQVINRLSQLAPLPNGAAPQISPTSPTGEIFRYRVVGPPGYSVMDLKTIEDWMLERRFKAVPGVVDVNGWGGKTKDYEVSIDMAKLMRYGLTVPQVLQVLNNSNINVGGQTVNFGAQAAVVRGVGMIHSLDNIRNTMVASLAGTPVLISDIATVSVGNVPRLGIAGNNADNDIVQGIVLMRRGEQSTPTILRVEQEVDKINHSGILPPGVHIEKIYDRSELIAITTHTVLENLVVGIALIFLVQWIFLGNLRSAVIVSATIPFALFFAIGIMTMRGESANLLSVGAIDFGLIVDATVIMVENVFRHLAESQAQRSLGSPMQHYTRSDTSLRGKFLTIAHAAAEVNRPIFFSAAIIIAGFLPLFTLSGVEGHIFGPMAKTYAYAIVGGLIATFTVSPALCALLLPEHVDETETFLVRWMRRIYTPVMEFAIVNRALILSGMAVLGLIAVIAVHTLGLEFLPKLEEGNLWIRASMPDSISLEEGNAYVNQMRLLIKSYPEVDSIVSQNGRPDDGTDASGFFNAEFFVPMKPSSSWPKGITKEKLTEDMSAKLQEKFPGVEFNFSQYIEDNVEEAASGVKGQNSVKLYGNDLAALEKSAAQIKAVMATVPGIADLSVFNALGQPTVKIDIDRVRAARYGLQPGDINATVQAAIGGQAAGNLYEEGSDRNFPIVVRLASQYRQNLDSIGRITIGAQNPNGSGVVQIPLSDVASVNLVSGASFIYREGQERYIPIKFSVRGRDLGGAVQEAQRKVAEQVKLPGGYRMEWVGEFGQLEDAMARLKIVVPLSLALIMLLLYFNFNSITDTLLAASVMPMALIGGIFALYVTGTPFSVSAAIGFIGLFGISVMEGIIVLSYYNQLIESGTERAHAIVQSCQTRLRPVMMTCSAACAGLLPAAFATGIGSQVQKPLALVVVGGILLAPVLILLVLPVLIQLFSKRTPFVDKQEKINLLNRTETPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWF4</accession>
    <name>A0A2S9GWF4_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 7">Ornithine carbamoyltransferase</fullName>
            <shortName evidence="7">OTCase</shortName>
            <ecNumber evidence="4 7">2.1.3.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">S2091_3363</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>carbamoyl phosphate + L-ornithine = H(+) + L-citrulline + phosphate</text>
            <dbReference type="Rhea" id="RHEA:19513"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:46911"/>
            <dbReference type="ChEBI" id="CHEBI:57743"/>
            <dbReference type="ChEBI" id="CHEBI:58228"/>
            <dbReference type="EC" id="2.1.3.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 1/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.3.3" evidence="4 7"/>
    <dbReference type="EMBL" id="PUGF01000017">
        <property type="protein sequence ID" value="PRC92021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92021">
        <property type="protein sequence ID" value="PRC92021"/>
        <property type="gene ID" value="S2091_3363"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00068">
        <property type="reaction ID" value="UER00112"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016597">
        <property type="term" value="F:amino acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004585">
        <property type="term" value="F:ornithine carbamoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006526">
        <property type="term" value="P:arginine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1370">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01109">
        <property type="entry name" value="OTCase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006132">
        <property type="entry name" value="Asp/Orn_carbamoyltranf_P-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006130">
        <property type="entry name" value="Asp/Orn_carbamoylTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036901">
        <property type="entry name" value="Asp/Orn_carbamoylTrfase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006131">
        <property type="entry name" value="Asp_carbamoyltransf_Asp/Orn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002292">
        <property type="entry name" value="Orn/put_carbamltrans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024904">
        <property type="entry name" value="OTCase_ArgI"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00185">
        <property type="entry name" value="OTCace"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02729">
        <property type="entry name" value="OTCace_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00100">
        <property type="entry name" value="AOTCASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00102">
        <property type="entry name" value="OTCASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53671">
        <property type="entry name" value="SSF53671"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00658">
        <property type="entry name" value="orni_carb_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00097">
        <property type="entry name" value="CARBAMOYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="OTCace_N" evidence="10">
        <location>
            <begin position="2"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="domain" description="OTCace" evidence="9">
        <location>
            <begin position="143"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Carbamoyl phosphate binding" evidence="7">
        <location>
            <begin position="45"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Carbamoyl phosphate binding" evidence="7">
        <location>
            <begin position="123"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Ornithine binding" evidence="7">
        <location>
            <begin position="215"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Carbamoyl phosphate binding" evidence="7">
        <location>
            <begin position="251"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="72"/>
        </location>
        <ligand>
            <name>carbamoyl phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58228"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="96"/>
        </location>
        <ligand>
            <name>carbamoyl phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58228"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="154"/>
        </location>
        <ligand>
            <name>L-ornithine</name>
            <dbReference type="ChEBI" id="CHEBI:46911"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="211"/>
        </location>
        <ligand>
            <name>L-ornithine</name>
            <dbReference type="ChEBI" id="CHEBI:46911"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="279"/>
        </location>
        <ligand>
            <name>carbamoyl phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58228"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00016634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC92021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="299" mass="33703" checksum="DEBA8AD7EEDBAB05" modified="2018-07-18" version="1">MSDLTLDEYHYVMERARIIKRKFKEYQIYHPLIDRTLVMIFEKNSTRTRLSFEAGMHQLGGAAIYLNTRDSQLGRGEPVEDAGQVISRMCDIIMIRTFGQDIIERFAANSRVPVINGLTNEHHPCQVFADVFTFIEHRGALTGKSVAWVGDANNMLYSWLQAAQIFGFHLNISTPKSYEVDLSRIPKSQTNYTLFTNPSDACVGASLVTTDVWTSMGYEAENQARLTAFDGWIVDAAKMARAQPDALFMHCLPAHRGEEVSAEVIDGPQSVVWDEAENRLHIQKALLEYLVIGKVVSPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWI1</accession>
    <name>A0A2S9GWI1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acetyltransferase (GNAT) family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3220</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000016">
        <property type="protein sequence ID" value="PRC92085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92085">
        <property type="protein sequence ID" value="PRC92085"/>
        <property type="gene ID" value="S2091_3220"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="5"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="160" mass="17391" checksum="46CF5254A848F725" modified="2018-07-18" version="1">MFNIIEANLATPAHAAALVELLNHYAMDAMGGGEPLSDQVKNTLAAELHKRPTARVVLAFDGEIPAGLIICFEGFSTFACKPLLNLHDVVVHQSYRGKGLFRLMLQQVESIAQELGCCKLTMEVLEGNHVALVAYKANGFAGYDLVAGMGQAVFWQKKLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWI4</accession>
    <name>A0A2S9GWI4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3186</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000016">
        <property type="protein sequence ID" value="PRC92051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92051">
        <property type="protein sequence ID" value="PRC92051"/>
        <property type="gene ID" value="S2091_3186"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="123" mass="13292" checksum="ABD6415D713218C1" modified="2018-07-18" version="1">MISKITNAVAICGILMLSACSTQGTFVIPEGSKLYLGGRPEPVKVEPDGTVDTYAFGWESMGVPPNKGIQYRLEEDGKTTQEGRLRPVLRVKAIFLPPIFGILAVPTGLNPNITYNLVTGKQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWJ7</accession>
    <name>A0A2S9GWJ7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3225</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000016">
        <property type="protein sequence ID" value="PRC92090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92090">
        <property type="protein sequence ID" value="PRC92090"/>
        <property type="gene ID" value="S2091_3225"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="649" mass="72758" checksum="09043B2607636216" modified="2018-07-18" version="1">MDNPVNQEVIFDQTILKLFPSSIVDSLISDSAFRDQYALKADPTFIFAKNGISVRRSSLFPCIREMLEDSNARPTLNDINGNELQLDLIQDGDERVIIITGNNQRIILPDFSPLSPIQSDRVSRFKRMSEEINFYGVEAEKWRVILESRALDDNELDKFMSNFSAIPITVAATITSAMNEAEIDFSSLVPHSEKYFERLVGECRQSTNIIDYAAEGLSDHINQLLSWNACEGFLLALLLSSHSSSALRICIDSLTDEDLVKVYVWLVNSGDRISQIGAIELGLTIVDQRPCIEAYLNKLIAEIHNDDANDLNSRFNLLSSLIAMVEGELARTKILKGKPPFWRRLASIAQASLIERTLIGRPLNIEMFAKHTWEYRGMLFYLQTMSDLRIEPRWYPHHLAPDQLKAECIGRIIDAANKNESRLQPTSLYGPLFNTTDGSLRSLLEVPFPFLPGPLEGSITPQNDPPEDILRAIKDRLQDEVLEPKSFAALVNSALLFKLTSSHAQLAIAALRAVKHQIKLSEDKEQMQLVLNGLATVAAVTRSPDLAEELKLLARGSLFGPSRFISPVDTLWIGLTAAAAHQELAGWSKFVGEWLLELACQSLKTDEISLLLRLTEWLCDITPELWYTCGRAHAALLVALMSNAKHQQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWN7</accession>
    <name>A0A2S9GWN7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC-type branched-chain amino acid transport systems periplasmic component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_3246</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the leucine-binding protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000016">
        <property type="protein sequence ID" value="PRC92111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92111">
        <property type="protein sequence ID" value="PRC92111"/>
        <property type="gene ID" value="S2091_3246"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028081">
        <property type="entry name" value="Leu-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000709">
        <property type="entry name" value="Leu_Ile_Val-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13458">
        <property type="entry name" value="Peripla_BP_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00337">
        <property type="entry name" value="LEUILEVALBP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015764877" evidence="3">
        <location>
            <begin position="25"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="domain" description="Peripla_BP_6" evidence="4">
        <location>
            <begin position="30"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC92111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="384" mass="40554" checksum="25167DE28C538389" modified="2018-07-18" version="1">MQIKSTMIPLVAAIAFAFAGSTFAADDMIVKIGHVGPISGPSAHLGKDNENGAKMAIEELNAKGTMIGGKKVKFELLTEDDGGDPKQGTAAAQKLVDAKVNGVVGHLNSSTSIPAAKIYHDAGIPQISPSSTATAFTSMGYKSTFRVVANDGQLGGTLGRYAVQTLNAKTIAVIDDRTAYGQGVADEFVKGAKSKNPVIKLALRQFTNDKATDFNAILTSIKAAKPDVVFFGGMDSVAGPMLRQMKALGIKAKFMGGDGICTTKLPELAGDGIIDDQVICAEAGGVVDAQKKANDDFRVAFKKRFGAEVIIYAPYVYDSVMTLADAMQQAKSSDPAVYLPFLQNIHHKGITGDIVFDKKGDIKDGTLTMYTFKSGKRELMGVVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWP4</accession>
    <name>A0A2S9GWP4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_3055</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92139">
        <property type="protein sequence ID" value="PRC92139"/>
        <property type="gene ID" value="S2091_3055"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="3">
        <location>
            <begin position="2"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="4">
        <location>
            <begin position="124"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="2">
        <location>
            <begin position="124"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC92139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="218" mass="24245" checksum="FC65527D5751FF4B" modified="2018-07-18" version="1">MHILIVEDDIDLGFALQKALKTNGLSSEWVRRVDHAPRSFESAPFDCILLDLCLPGGAGLDLLKLWRDDGIVIPIIVITARSALDDRLAGLDSGADDYLVKPFATAELISRIYAVQRRYVRQASDIWSVGDIEIEPRKYLARLNGTLLDLSPREFRLILELAREPGVVMPKGELSQRLEPLGDPVDFSAIEVHISNLRRKIGAHRIQTVHGVGYTLAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWW9</accession>
    <name>A0A2S9GWW9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3133</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92217">
        <property type="protein sequence ID" value="PRC92217"/>
        <property type="gene ID" value="S2091_3133"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="14"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="41"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="162" mass="18176" checksum="8F3EC5E3EC2F9FC0" modified="2018-07-18" version="1">MSIAISVLLHPSKILRLCAISFSILLVLIGIYIGCLDVPSILIRSFLAVLCGLAAYRIFFQHQKNAKKIWHIAIDGKGQLRCLPVSSSAITPTNREFFESNPFYLMSGTTLWARVLFLRLHCLEDDVMINLVILSDALSRDEFRRLSVACKWIVAHAESPTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GX50</accession>
    <name>A0A2S9GX50_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2940</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92281">
        <property type="protein sequence ID" value="PRC92281"/>
        <property type="gene ID" value="S2091_2940"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="302" mass="33269" checksum="68D3CA81BE18FD83" modified="2018-07-18" version="1">MDQFKQISTFVEVVTKGSLSAAARAEGVAPSLIGRRIDALEQRLGVKLLQRTTRKIVLTNEGMAFLDNCQRILAELEEAEAAVSERNANAVGQLTISAPAGFGRQHVAPLIPSFLAEHQQVNVTLNLNDRVVDLIGDGVDIAIRIATLNDSSLIGVKLADNQRVVVASPAYIKRHGTPRTLADLARHNCLAFNNDGSQRGWTFRQQGKNITHKVSGNMVCNDGEVLHDWALAGKGLAWRSMWEVGAELTTGKLVSVLDEFAAPDHDIYAVFAQKRHLPLRIRLFVDFLKHAYSTPNYWNKKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GX66</accession>
    <name>A0A2S9GX66_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2968</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92309">
        <property type="protein sequence ID" value="PRC92309"/>
        <property type="gene ID" value="S2091_2968"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="121" mass="13580" checksum="AB6FB4FEE646607F" modified="2018-07-18" version="1">MRVLITGSTTWTDIKALRREFAFLPKETIIITGDTSGVDAFANEVAPEFGFVVELMKKTKEDYETYPDNGWKGLNDRMIRTGIDLLLAFHPEYGKPGLALGTRHAVELAEQAGIQVIIFYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GX95</accession>
    <name>A0A2S9GX95_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2989</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92330">
        <property type="protein sequence ID" value="PRC92330"/>
        <property type="gene ID" value="S2091_2989"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1490.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018988">
        <property type="entry name" value="DUF2000"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023476">
        <property type="entry name" value="Pep_tRNA_hydro_II_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017021">
        <property type="entry name" value="UCP033763"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09391">
        <property type="entry name" value="DUF2000"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF033736">
        <property type="entry name" value="UCP033763"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102462">
        <property type="entry name" value="SSF102462"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="133" mass="14609" checksum="CFDCD40C3F08FB30" modified="2018-07-18" version="1">MKKCVIIVNKDLPLGLKANISAVLCMSLGKIHPEIVGADLIDADNNIYIGITTIPVPILETHTDAIKAAKILADEDTTLAIVFNCSALSTKDYTAYETNIRNKKTSDIVFHGLLMYGEKIYVNKITGKFPLMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXT6</accession>
    <name>A0A2S9GXT6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2907</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92532">
        <property type="protein sequence ID" value="PRC92532"/>
        <property type="gene ID" value="S2091_2907"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="185" mass="20190" checksum="C1397027E2B1CC0A" modified="2018-07-18" version="1">MIANRNASRLASAWIVSTLLITGCASSPSQISSEKFIKLPLVPGWFEGKRVWYVTTDMSDHAMATGGNANFVPSLANALPPDPPVPGTPLSIDRIYKFMNFDQGSVLPSIPQPLGGANSNREYSPLWQLYAVYWQPGKTPHELHSEKEVLEAQDSGLIRIKALRIIVNCPVIKVENALLPGAELP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXZ6</accession>
    <name>A0A2S9GXZ6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glutathione S-transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_2650</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GST superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92595">
        <property type="protein sequence ID" value="PRC92595"/>
        <property type="gene ID" value="S2091_2650"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00043">
        <property type="entry name" value="GST_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02798">
        <property type="entry name" value="GST_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="SSF47616"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GST N-terminal" evidence="2">
        <location>
            <begin position="1"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="3">
        <location>
            <begin position="89"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC92595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="230" mass="25969" checksum="4E0E881ED80D7D40" modified="2018-07-18" version="1">MIELYSWPTPNGHKIHIMLEECGLPYHVTPVDIGAGDQFKPEFLRISPNNKIPAMLDTDGPDGQPITLFESGAILLYLAGKTGLFLGDTTHEKYNALQWLMFQMGGFGPLLGQAHHFRIYAPEPIPYAIDRYTNEARRLYGVIDTQLAQSTYLAGDNYSIADIATFAWARSWQNQGIDWADFPHAKLWFDAINARHAVQRGVQVLADLRKPLVSKEAKEMLFGTTQYQKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GY39</accession>
    <name>A0A2S9GY39_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2688</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92633">
        <property type="protein sequence ID" value="PRC92633"/>
        <property type="gene ID" value="S2091_2688"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="74" mass="8357" checksum="5F6F2456B4FE6118" modified="2018-07-18" version="1">MKMFRKLIADYLLLIVLLVIVAGTLNFIDDGYQDEVLDQQVLDESISQAKADHAQRQHELKALQIQASNMTGVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYA4</accession>
    <name>A0A2S9GYA4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2746</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92691">
        <property type="protein sequence ID" value="PRC92691"/>
        <property type="gene ID" value="S2091_2746"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="159" mass="17308" checksum="61ED05BF69A84910" modified="2018-07-18" version="1">MLGIYTIYAKIAGVVALVVAILFGLWYLDHRGFVRGEATIQDQWDKAQRQATADTLKIQQANDKKLNESEQKYVDQKNANDALLADTRKSGGLFYTPTVCPVSVPSATKAVASVDPASSPGRNDSGTINLTEFAEEVEQLGHDKDELAIRLNAIAAENK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYA6</accession>
    <name>A0A2S9GYA6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyl transferases group 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2437</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92707">
        <property type="protein sequence ID" value="PRC92707"/>
        <property type="gene ID" value="S2091_2437"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="179"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="339" mass="37855" checksum="AC39C047F24D6F7B" modified="2018-07-18" version="1">MGRLLLHAPNVHVGGGLVLLKELLLALTFEEGWANLDKRAFELLCLPPKMDCNFVSPSLMGRLQAEFRLRHVARHDDLILCFHGMPPLLRVAGRVVVFQQNRNYLGLSPLSSFLGRTKVRVALERFICRSFKNHVNEYIVQTSSMQSAVKAWHGGNPIVRVIPFMDILVVESVSCADARKYDFIYVADGEAHKNHRNLLAAWILLAKEGIFPSLALTLGDSYNSLRREIDNANSTHNLNITNLGLLPHKKVLDLYHSGKALIFPSTAESFGLPLLEASHTGMPIVASELDFVRDVCQPTQTFDPNSPVSIARAVKRLWNIPTEPIEIGSAHDFLEVLLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYD7</accession>
    <name>A0A2S9GYD7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">WecB: UDP-N-acetylglucosamine 2-epimerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2440</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UDP-N-acetylglucosamine 2-epimerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92710">
        <property type="protein sequence ID" value="PRC92710"/>
        <property type="gene ID" value="S2091_2440"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008761">
        <property type="term" value="F:UDP-N-acetylglucosamine 2-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003331">
        <property type="entry name" value="UDP_GlcNAc_Epimerase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029767">
        <property type="entry name" value="WecB-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43174">
        <property type="entry name" value="PTHR43174"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02350">
        <property type="entry name" value="Epimerase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00236">
        <property type="entry name" value="wecB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase_2" evidence="2">
        <location>
            <begin position="28"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="375" mass="42368" checksum="68A02FE602F711B9" modified="2018-07-18" version="1">MLKVMTIVGTRPEIIRLSRVIALLDQYCEHTLVHTGQNYDYELNQVFFDDLGIRKPDCFMEAAGETAAETIGKVIAATDKVIDAYQPEAILILGDTNSALAAITAKRKKVPIFHMEAGNRSFDFRVPEEINRRIVDHTSDINLPYSAIARDYLLREGLAPDRIIKTGSPMYEVLTHYRTGIDASDVVQRLNLEQGKFFVVSAHREENVDSPQNLVKLAGILNQLAETYQEPVIVSTHPRTQKRIDAAGLIFHPLVRLMKPLGFNDYVKLQMCSHAVLSDSGTITEESSILNFPALNIREAHERPEGFEEAAVMMTGLELKRVFQALKILESQPKGEQRALRLVEDYSMPNVSEKVLRIILSYTDYVNRVVWKKTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYF9</accession>
    <name>A0A2S9GYF9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Anthranilate phosphoribosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_2492</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92762">
        <property type="protein sequence ID" value="PRC92762"/>
        <property type="gene ID" value="S2091_2492"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004048">
        <property type="term" value="F:anthranilate phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000162">
        <property type="term" value="P:tryptophan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1030.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005940">
        <property type="entry name" value="Anthranilate_Pribosyl_Tfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000312">
        <property type="entry name" value="Glycosyl_Trfase_fam3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017459">
        <property type="entry name" value="Glycosyl_Trfase_fam3_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036320">
        <property type="entry name" value="Glycosyl_Trfase_fam3_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035902">
        <property type="entry name" value="Nuc_phospho_transferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43285">
        <property type="entry name" value="PTHR43285"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02885">
        <property type="entry name" value="Glycos_trans_3N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00591">
        <property type="entry name" value="Glycos_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47648">
        <property type="entry name" value="SSF47648"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52418">
        <property type="entry name" value="SSF52418"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="3" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="1 6" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0822">Tryptophan biosynthesis</keyword>
    <feature type="domain" description="Glycos_trans_3N" evidence="5">
        <location>
            <begin position="11"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_3" evidence="4">
        <location>
            <begin position="101"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC92762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="319" mass="34580" checksum="39F5F729C0EFFE22" modified="2018-07-18" version="1">MTTLFPTAHFIKEIGRGVKGARSLSQADAGELFNAMLHGQVSDLELGAILLAMRIKGESVAEIAGFLESAEKSFQLLQAPNSADCEYAPIVIPSYNGARRVANLTPLLAMLLARAGAPVLVHGVQKDAGRVTSAEIFQELGIAASSSLEQAEQQLNQPQPVFMPIEILAPRLAQMLALRRILGVRNSTHTLVKIMQPFVQPALRLTSYTHPEYLSMLSDYFANAADPARGDVFLMRGTEGETVANTKKVQQIAWFHAGQKNTLIEAEHGTDLALTVPVDATVTALWIKEVLAGRESVPENIAEQVRHCLSVAKRLKALV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYM2</accession>
    <name>A0A2S9GYM2_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Oxygen-dependent coproporphyrinogen-III oxidase</fullName>
            <shortName evidence="5">CPO</shortName>
            <shortName evidence="5">Coprogen oxidase</shortName>
            <shortName evidence="5">Coproporphyrinogenase</shortName>
            <ecNumber evidence="5">1.3.3.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">hemF</name>
        <name evidence="6" type="ORF">S2091_2552</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>coproporphyrinogen III + 2 H(+) + O2 = 2 CO2 + 2 H2O + protoporphyrinogen IX</text>
            <dbReference type="Rhea" id="RHEA:18257"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57307"/>
            <dbReference type="ChEBI" id="CHEBI:57309"/>
            <dbReference type="EC" id="1.3.3.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="5">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; protoporphyrinogen-IX from coproporphyrinogen-III (O2 route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1 5">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the aerobic coproporphyrinogen-III oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.3.3" evidence="5"/>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92822">
        <property type="protein sequence ID" value="PRC92822"/>
        <property type="gene ID" value="S2091_2552"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00251">
        <property type="reaction ID" value="UER00322"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004109">
        <property type="term" value="F:coproporphyrinogen oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042803">
        <property type="term" value="F:protein homodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006782">
        <property type="term" value="P:protoporphyrinogen IX biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1500.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00333">
        <property type="entry name" value="Coprogen_oxidas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001260">
        <property type="entry name" value="Coprogen_oxidase_aer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036406">
        <property type="entry name" value="Coprogen_oxidase_aer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018375">
        <property type="entry name" value="Coprogen_oxidase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10755">
        <property type="entry name" value="PTHR10755"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01218">
        <property type="entry name" value="Coprogen_oxidas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000166">
        <property type="entry name" value="Coproporphyri_ox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00073">
        <property type="entry name" value="COPRGNOXDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102886">
        <property type="entry name" value="SSF102886"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01021">
        <property type="entry name" value="COPROGEN_OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5" id="KW-0350">Heme biosynthesis</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4 5" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="106"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Important for dimerization" evidence="5">
        <location>
            <begin position="238"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="256"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="5">
        <location>
            <position position="104"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="90"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="94"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="104"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="143"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="173"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="site" description="Important for dimerization" evidence="5">
        <location>
            <position position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC92822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="299" mass="34002" checksum="42BB15A6C140ED43" modified="2018-07-18" version="1">MTNTAVKNFFLSLQNNIVTALEQLDGLAFLTDSWERPEGGGGISRVIEQGGFFERGGVNFSHVMGTNLPPSAAASRPELAGRSWEAMGVSLVLHPRNPYSPTVHMNVRFFSTHAEGQEPVWWFGGGMDLTPYYGFAEDAQHFHQTCKNALTPFGSELYPEFKAWCDNYFYLKHRQEPRGIGGIFFDDFNRLPFEDSYAMVQQVANAFIPAYLPIAERTKNLAYGERERDFQAYRRGRYVEFNLVFDRGTLFGLQSGGRTESILMSMPPSVTWRYNWQPEAGSPEAQLYSDFLIHKDWLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYU7</accession>
    <name>A0A2S9GYU7_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_2314</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92897">
        <property type="protein sequence ID" value="PRC92897"/>
        <property type="gene ID" value="S2091_2314"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="745"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="773"/>
            <end position="790"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="5">
        <location>
            <begin position="117"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC92897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="810" mass="89760" checksum="A73B8FCAE998D9B7" modified="2018-07-18" version="1">MGTTYLRRCPSCGTEHQPEIMRCLCGTPLAGVDLIRKTALAVEVKSNPTPVKNAADTLLCPFADCGQPNPAGSLVCLYCDRPLTKPATQQTSVQAVTTAGTITNLINLPSQLSKRYRITETMPARGAEAELLLVQALTGGAILVAKIYRHGILPKPEIQQRIANIAREHRVDVLEAGVSDGYAYELMELCEGGSLRRLLEQYRGTYPDQLPSNIVRRIVQELAIALAAVHATGLVHRDLKPENILIRSEQPLDLVLTDFGIASVLNATQRFTGVARTLPYAAPESLSGVIDAKADYWALGIITLEAATGVHPFAGLSDAVILHHLTTRNIATTGIQDKQINKLARGLLQRDPKLRWGASELQRWLAGDTTLADPLNEQLGSSSSLGSNFNQPYHIGEQRCHQPEQLGVALAQHWEQGVADISNGQLLAWFRDVQKDQNTVRLLLDMRSNTIQSVDVQLLKLILHLAPGIPPIWHAQSIALPVILSQANLALKGDAAAAHWLHDLYQYRVLDIYAQAGNQTAGEVNQRWTAAIDQVNSAWQKVSTIINASHDSAQAPNIDKLMYGSDALSRPPLSAMHARILAFCYDQNWAERLRQRVFAEIGNLTVNCPWLADLGDPRTMSSADLLVTENLLPEARLAAERQIKTNQRKQEQQQYDFQELKQEVSDILTELRQLTDTHMLSTDECEQLQRICDNYFEHIAQIRSSGRVDSTWLEMKKSVLRSEHIVHQLMQKVNSLSEHRAITAGWVNGSTLSFGVGLAVIALFAIRFFSRSVSFLFIAAAIGIAIWRFLPDYLLMRQIRELGQRLPAKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYV4</accession>
    <name>A0A2S9GYV4_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">50S ribosomal subunit assembly factor BipA</fullName>
            <ecNumber evidence="2">3.6.5.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">GTP-binding protein BipA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">bipA</name>
        <name evidence="4" type="ORF">S2091_2297</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>GTP + H2O = GDP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="2">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="2">Binds to ribosomes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.-" evidence="2"/>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92880">
        <property type="protein sequence ID" value="PRC92880"/>
        <property type="gene ID" value="S2091_2297"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000027">
        <property type="term" value="P:ribosomal large subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03710">
        <property type="entry name" value="BipA_TypA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.250">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00849">
        <property type="entry name" value="BipA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035651">
        <property type="entry name" value="BipA_V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000640">
        <property type="entry name" value="EFG_V-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042116">
        <property type="entry name" value="TypA/BipA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006298">
        <property type="entry name" value="TypA_GTP-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42908:SF8">
        <property type="entry name" value="PTHR42908:SF8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00679">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00838">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="SSF54980"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01394">
        <property type="entry name" value="TypA_BipA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="2" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="Tr-type G" evidence="3">
        <location>
            <begin position="6"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="18"/>
            <end position="23"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="131"/>
            <end position="134"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC92880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="611" mass="68200" checksum="A1B404D43D587497" modified="2018-07-18" version="1">MSNIKRAIRNIAIIAHVDHGKTTLVDQLLRQSGTFRDNQQVDARVMDSNDIEKERGITILSKNCAVEYKGTHINIVDTPGHADFGGEVERVLSMVDSVLLLVDAQEGPMPQTRFVTRKALALGLKPIVVVNKVDRENADPQKAVNATFELFDKLGATDEQLDFPIVYASGFKGYAGLEDSVREGNMEPLFDAILKHVPAREDDPDGPLQLQITSLEYSSYVGKIGVGRILRGKVKALQDVVWMNGPDDKPTKARINQVLTFKGLDRVIADEALAGDIVLINGIEEISIGSTICAPDTPEGLPMLKIDEPTLTMNFMVNNSPLAGREGKFVTTRQIRDRLDRELKSNMALRVVQAENDDSTYEVSGRGELHLTILIENMRREGFELAVSRPRVVFKMVGDVRHEPYEMLTVDVEENNQGGVMEELGRRRGDLQNMEPDGKGRVRLEYRIPARGLIGFQGEFMTLTRGTGLMSHVFDEYAPVDNTKGEMAGRRNGVLVSQDDGAAVAYAIWKLQDRGRMFVVHNDPVYEGMIIGIHSRDNDLVVNPIKGKQLTNVRSSGTDEAVRLVPPIQMSLEYAVEFIEDDELVEVTPKSIRLRKRYLKEHERKKASRDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYZ8</accession>
    <name>A0A2S9GYZ8_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_2371</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92954">
        <property type="protein sequence ID" value="PRC92954"/>
        <property type="gene ID" value="S2091_2371"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013767">
        <property type="entry name" value="PAS_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00989">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Histidine kinase" evidence="4">
        <location>
            <begin position="136"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC92954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="356" mass="39997" checksum="DBF5A88928946195" modified="2018-07-18" version="1">MERTASFAGLDLLASSVLVLDGQGCIRYANAAAEDLLKTSLKSLSNQKMADLFMNGQELQHLFEQALEYQFADKRQDLILERAGHEPLQVHSIFTVLDNSDTPVLIELRENVQQIKQDREDRMLDHSQANKELIRNLAHEIKNPLGGIRGAAQLLEMELPERHAKELREYTQVIIKEADRLQTLVDRLLAPHRLPHIVGDVNIHEVCERVRSLIMAEFPLGLTIQRDYDLSIPDFRGDVEQLIQSVLNIAHNAAQALAERIELGDAELIFKTRVVRQVTIAKIRYRLALDLHIIDNGPGISADIVDRIFFPLVSGRDGGSGLGLTLAQTFVQQHLGVIECESRPGVTDFRVLIPLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZE5</accession>
    <name>A0A2S9GZE5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative phage terminase, small subunit, P27 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2163</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93077">
        <property type="protein sequence ID" value="PRC93077"/>
        <property type="gene ID" value="S2091_2163"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006448">
        <property type="entry name" value="Phage_term_ssu_P27"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05119">
        <property type="entry name" value="Terminase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01558">
        <property type="entry name" value="sm_term_P27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="154" mass="16703" checksum="64FE9E8BD3627FC9" modified="2018-07-18" version="1">MAGRPPKPTALKIVGGNAGKRGMNKQEPDPTYLQDLTAPEWLPNRAKIIWNELAPHLSAAKLLTNVDIELLSQGCVAIANFRLSTEKSGEDLVKGGGFEKGESLNPWMIVQSMSFKQAMAVFQQFGMSPAARTRIAIQPQGDLFGGEDKAAAYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZN1</accession>
    <name>A0A2S9GZN1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putative membrane protein required for colicin V production</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_2249</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93163">
        <property type="protein sequence ID" value="PRC93163"/>
        <property type="gene ID" value="S2091_2249"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009403">
        <property type="term" value="P:toxin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003825">
        <property type="entry name" value="Colicin-V_CvpA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02674">
        <property type="entry name" value="Colicin_V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="41"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="79"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC93163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="140" mass="15315" checksum="050C74DB61B03ACA" modified="2018-07-18" version="1">MRGLLKEILSLASWVIAFLVANAYGAQLAEFIPLTEQSIRLITAFVSLFIGVRLLMWLLTMALDSIITASGLKSVDRSLGSLFGAARGCVIVLALTFVCGMTNLPQQAFWREAFFRPTVETAALVVKPLLPGSFARYVNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZX5</accession>
    <name>A0A2S9GZX5_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Peptidoglycan D,D-transpeptidase MrdA</fullName>
            <ecNumber evidence="2">3.4.16.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Penicillin-binding protein 2</fullName>
            <shortName evidence="2">PBP-2</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">mrdA</name>
        <name evidence="6" type="ORF">S2091_2005</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes cross-linking of the peptidoglycan cell wall.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the transpeptidase family. MrdA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.16.4" evidence="2"/>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93267">
        <property type="protein sequence ID" value="PRC93267"/>
        <property type="gene ID" value="S2091_2005"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008658">
        <property type="term" value="F:penicillin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009002">
        <property type="term" value="F:serine-type D-Ala-D-Ala carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02081">
        <property type="entry name" value="MrdA_transpept"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005311">
        <property type="entry name" value="PBP_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036138">
        <property type="entry name" value="PBP_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001460">
        <property type="entry name" value="PCN-bd_Tpept"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017790">
        <property type="entry name" value="Penicillin-binding_protein_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03717">
        <property type="entry name" value="PBP_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00905">
        <property type="entry name" value="Transpeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56519">
        <property type="entry name" value="SSF56519"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03423">
        <property type="entry name" value="pbp2_mrdA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="2" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="2" id="KW-0133">Cell shape</keyword>
    <keyword evidence="2" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 2" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="domain" description="PBP_dimer" evidence="5">
        <location>
            <begin position="62"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="domain" description="Transpeptidase" evidence="4">
        <location>
            <begin position="270"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="625"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="625"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-ester intermediate" evidence="2">
        <location>
            <position position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC93267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="673" mass="74327" checksum="C806286D1A28A071" modified="2018-07-18" version="1">MTEFKNTERELYFFRIRLFAIAGFILLCFTLLFARFVWLQIVKHEVYATQAEDNRISIVPVVPNRGLILDRNGVVLARNFSAYTLEITPSKINQDLDVVIDQLAELVDIQPKHRKRFKKLMEDSKSFESLPIRTRLTDEEVARFTVQRFRFPGVEIQARLFRQYPLGEIASHVIGYIGRISASDAKKLDASEEDSDNYFGTDYIGKEGLEKSYERQLHGTTGSEEVEVSARGRAVRALSRDPATSGSNLILSIDIELQKIVEEAFGDKRGALVAIDPETGDVLAFVSKPTYDPNLFVEGIDQANWDSLNTSIDKPLVNRALSSSYPPGSTYKPFMGLAGLELGKRTPSSAIADAGYFMLGGHRFNDDKVGGHGIVDLYRSIVVSCNTYYYMLANDIGVDAIHDFMAPFGFGEKTGIDLEHESSGILPSTAWKRARYKKPAQQKWFAGETISLGNGQGYNSFTILQMAHAVATLANNGIVMKPHLVKMIEDPQTHARTLTVPKESARIPLKQENIDFIKNAMAGVTKFPEGTSRLVFVNAGYESAGKTGTAQVIGIKKGEKYNANNIALRFRDHALYTAFAPVDKPRIAIAMIVENGGFGAAGAAPIAKLALDYYLLGKRPGDKEKEMLKEMDKDTTPVEHVDPSQMQSEAEAKAEAESEGGPQPGAVTSAPKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZZ7</accession>
    <name>A0A2S9GZZ7_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B</fullName>
            <shortName evidence="10">Asp/Glu-ADT subunit B</shortName>
            <ecNumber evidence="10">6.3.5.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">gatB</name>
        <name evidence="12" type="ORF">S2091_2011</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9 10">Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>ATP + H2O + L-aspartyl-tRNA(Asn) + L-glutamine = ADP + 2 H(+) + L-asparaginyl-tRNA(Asn) + L-glutamate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:14513"/>
            <dbReference type="Rhea" id="RHEA-COMP:9674"/>
            <dbReference type="Rhea" id="RHEA-COMP:9677"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:78515"/>
            <dbReference type="ChEBI" id="CHEBI:78516"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 10">
            <text>ATP + H2O + L-glutamine + L-glutamyl-tRNA(Gln) = ADP + H(+) + L-glutamate + L-glutaminyl-tRNA(Gln) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:17521"/>
            <dbReference type="Rhea" id="RHEA-COMP:9681"/>
            <dbReference type="Rhea" id="RHEA-COMP:9684"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:78520"/>
            <dbReference type="ChEBI" id="CHEBI:78521"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="4 10">Heterotrimer of A, B and C subunits.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the GatB/GatE family. GatB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.-" evidence="10"/>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93273">
        <property type="protein sequence ID" value="PRC93273"/>
        <property type="gene ID" value="S2091_2011"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050566">
        <property type="term" value="F:asparaginyl-tRNA synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050567">
        <property type="term" value="F:glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00121">
        <property type="entry name" value="GatB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004413">
        <property type="entry name" value="Apn/Gln-ADT_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017959">
        <property type="entry name" value="Asn/Gln-tRNA_amidoTrfase_suB/E"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006075">
        <property type="entry name" value="Asn/Gln-tRNA_Trfase_suB/E_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018027">
        <property type="entry name" value="Asn/Gln_amidotransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003789">
        <property type="entry name" value="Asn/Gln_tRNA_amidoTrase-B-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042114">
        <property type="entry name" value="GatB_C_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023168">
        <property type="entry name" value="GatB_Yqey_C_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017958">
        <property type="entry name" value="Gln-tRNA_amidoTrfase_suB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014746">
        <property type="entry name" value="Gln_synth/guanido_kin_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11659">
        <property type="entry name" value="PTHR11659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02934">
        <property type="entry name" value="GatB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02637">
        <property type="entry name" value="GatB_Yqey"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00845">
        <property type="entry name" value="GatB_Yqey"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55931">
        <property type="entry name" value="SSF55931"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89095">
        <property type="entry name" value="SSF89095"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00133">
        <property type="entry name" value="gatB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01234">
        <property type="entry name" value="GATB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="6 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8 10" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GatB_Yqey" evidence="11">
        <location>
            <begin position="331"/>
            <end position="484"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PRC93273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="486" mass="53316" checksum="9EC4072F528222D5" modified="2018-07-18" version="1">MQWEVVIGFETHAQLSTKSKIFSGSTTQFGAEPNTQASPVDLALPGVLPVLNRGAVEKAIQFGLAVNSTIAPMSVFARKNYFYPDLPKGYQISQFELPVVQGGVVSFAMERDGKTEIRSVQLTRAHLEEDAGKSLHEDYQGMSGIDLNRAGTPLLEIVTEPVMRSAAEAVAYAKALHSLVTWLGICDGNMQEGSFRCDANVSVRPVGQVEFGTRCEIKNLNSFRFLEEAINIEVRRQIELIEDGGRVVQETRLYDPDKKQTRSMRSKEDSQDYRYFPDPDLLPLVISQEWINRVKADMPELPAAMRSRFIEQFGLSEYDAMVLTQTKASANYFEAVVTHAGAAQAKPAANWMMGDVASTLNREGMEMTAIPVKAEQLALLLQRIADGTISNKIAKEVFAAMWQAPSADVNLADQVIEAKGLKQISDPGALAKIIDDVLAANQKSVEEFRAGKEQAINSLLGQAMKATKGKGNPTEMKALLLAKLNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H066</accession>
    <name>A0A2S9H066_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Competence/damage-inducible protein CinA C-terminal domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1762</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93375">
        <property type="protein sequence ID" value="PRC93375"/>
        <property type="gene ID" value="S2091_1762"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.950.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036653">
        <property type="entry name" value="CinA-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008136">
        <property type="entry name" value="CinA_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02464">
        <property type="entry name" value="CinA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142433">
        <property type="entry name" value="SSF142433"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00199">
        <property type="entry name" value="PncC_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CinA" evidence="1">
        <location>
            <begin position="5"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="159" mass="16477" checksum="78B8EB7806E8278C" modified="2018-07-18" version="1">MDDLTQLATKVGVLLTEKNILLATAESCTGGGVAQAVTEISGSSIWFECGFITYSNSSKSELLDISPALIAQHGSVSEEIAAAMAEGALANCEAHVALATTGIAGPLGAVPGKPVGTICFAWSMNGKTHTERLLFSGDRKSVREQTVVHALKGLLQFLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H069</accession>
    <name>A0A2S9H069_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="13">P pilus assembly protein porin PapC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">S2091_2088</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell outer membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the fimbrial export usher family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93350">
        <property type="protein sequence ID" value="PRC93350"/>
        <property type="gene ID" value="S2091_2088"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015473">
        <property type="term" value="F:fimbrial usher porin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009297">
        <property type="term" value="P:pilus assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2070">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2610">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000015">
        <property type="entry name" value="Fimb_usher"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042186">
        <property type="entry name" value="FimD_plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025949">
        <property type="entry name" value="PapC-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043142">
        <property type="entry name" value="PapC-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025885">
        <property type="entry name" value="PapC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037224">
        <property type="entry name" value="PapC_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30451">
        <property type="entry name" value="PTHR30451"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13953">
        <property type="entry name" value="PapC_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13954">
        <property type="entry name" value="PapC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00577">
        <property type="entry name" value="Usher"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141729">
        <property type="entry name" value="SSF141729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1134">Transmembrane beta strand</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015622169" evidence="10">
        <location>
            <begin position="32"/>
            <end position="883"/>
        </location>
    </feature>
    <feature type="domain" description="PapC_N" evidence="12">
        <location>
            <begin position="57"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="domain" description="PapC_C" evidence="11">
        <location>
            <begin position="791"/>
            <end position="855"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF13953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF13954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PRC93350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="883" mass="94401" checksum="6BD19420E345DCBB" modified="2018-07-18" version="1">MDNCLATLATLLSRQLALLVLTVAVSNACMAMGTGLNNNSSNGATVESASTALYGGFDSSMLAGGIGNKIDVSQFTHGNPTLPGKYRVDVYINQQWLGRRDIEIIAIPGKDQAELCVTKGLLVQMGVEFSTLPTPEDPSVSDGEKCFDVEKKIPAAMVDFDSSDLRLSLSIPQLYLSHISRGYVSPDDWDKGIDAGFFSYNLNSFHSSNGQIDSNLFYAGINLGINVDGWRYRYNGSYSTNTSTNSTETAQQNGHWQLNSSYLQHDITSLKSQLTIGDSYSNGDLFDSVSFQGVQIASDDRMLPESQRGYAPVIHGVAETNAKVTVRQGGNVIFETNVPPGEFKIDDMYNSGSSGDFVVTVTEADGRQKQFTVPYSAGVLLLRPGASRYSAVIGKLLNVTSQDAPIFSEVIYQHGLGHGITAYAGGIAAEYYSSAQLGMALNTSLGAIGVDLTRSVTKQAPQDSTLLGRSWRLSYSKVLEQTHTNFGLAAYRYSSGDFLTLSNAALLHVEQEVTGITSPLLLPENSFQVSFSQPISERFGSVYLNGTAQNYWNGAPSAVSYQAGYSNTRPWGTFGASLGRTIDATGIYHNLFTVSFSLPLGNEAFMHRPTLSVTASHGDNQTTEQVALNGTVGENNRFSYNAYNNYVSSNSTSTNSTNIVGAGLQYAAQYGQLSASYSAGEGRQSAISASGALILHQGGLILAPSLGETIGIVYAPGAEGASVINANGGKINRDGYAVIPFLIPYSNNDVIIDPKGSGMNVELDTTSQQIAPRAGAIVLLKYSTTIGRAVLMTINLVDGRAPPLGATVLDEAGKEIGMLAQGGRFFNRKLTDKGRLTVKWGAGREQQCIASYTMPAEAESENELPFQQLTVSCLSDVQMVSTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H080</accession>
    <name>A0A2S9H080_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Citrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1779</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93392">
        <property type="protein sequence ID" value="PRC93392"/>
        <property type="gene ID" value="S2091_1779"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015128">
        <property type="term" value="F:gluconate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003474">
        <property type="entry name" value="Glcn_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30354">
        <property type="entry name" value="PTHR30354"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="57"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="98"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="178"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="232"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="279"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="439"/>
            <end position="460"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="463" mass="48918" checksum="7FFD2258842554DA" modified="2018-07-18" version="1">MALLVVLAALFLLMFVAYRGFSVILFAPIIALAAVFLTDPGMVAPMFTSVFMEKMVGFLKLYFPVFLLGALFGKVIELSGFSKAIVSSIIQVVGSQRAILSIVLVCAVLTYGGVSLFVVVFAVYPFAAEMFKQGNIPKRLIPGTIALGAFSFTMDSLPGTPQIQNIIPSTFFKTTTWAAPWLGVIGGMFILLMGMLYLEWRRKAALAKGEGYGENHLNEPEAFTHEKLPNPLIALLPLVLVAVLNKVFTGLIPQLYGQSYNLQLAGNAKPVVTEISKVAAIWAVEAALLVGILTVLVLAFKPIKKQFADGSKAAIAGALLAATNTATEYGFGAVIASLPGFLIVADALKSIPNPLVNEAITVTALAGITGSASGGLSIALAAMSDTFIQAANAAHIPLEVMHRIASMASGGMDTLPHNGAVITLLAVTGLTHRVSYGDIFAVTCIKTMAVFFVIAVYYATGIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0J3</accession>
    <name>A0A2S9H0J3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1886</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93499">
        <property type="protein sequence ID" value="PRC93499"/>
        <property type="gene ID" value="S2091_1886"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="163" mass="18132" checksum="124C93EBC545E7EF" modified="2018-07-18" version="1">MANFFKQTVYVQISAQKLTVTSPESGKFISETPWIAINKKLPVNKMVVSIGEDAYQLRGQPDTEVINPFTHPRSLFSDFTCAEYLIKSFIKKLEIKNFFAPNPIIIIHPLVDPEGGFTQIEFRVMRELALGAGASKAIVWVGSTLSNQDIISGLFPLSGKIIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1D2</accession>
    <name>A0A2S9H1D2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Alpha/beta hydrolase fold</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_1398</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S33 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93789">
        <property type="protein sequence ID" value="PRC93789"/>
        <property type="gene ID" value="S2091_1398"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013595">
        <property type="entry name" value="Pept_S33_TAP-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002410">
        <property type="entry name" value="Peptidase_S33"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08386">
        <property type="entry name" value="Abhydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00793">
        <property type="entry name" value="PROAMNOPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015504155" evidence="4">
        <location>
            <begin position="28"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="domain" description="AB hydrolase-1" evidence="5">
        <location>
            <begin position="80"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="domain" description="Abhydrolase_4" evidence="6">
        <location>
            <begin position="364"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="478"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="479"/>
            <end position="505"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC93789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="505" mass="55074" checksum="AD1661FD8BD41965" modified="2018-07-18" version="1">MNTVMMWKRLGCMLFLWAAASCISAHASDLLKPCRVDGFAQQVQCGQIQRPLNPDEPNGKQISLHFIVLTAQDKSKAPDPIFLLAGGPGQSAINVASWMKAMFEKLQRRRDLVFVDQRGTGKSAPLICPESSDLKGIGEADHEVQEALKCKTQLEKLPYGDLRFFTTSIAMQDLDAVRAALNYPQINLIGISYGTRAALEYARQFPTKVRRSVLDGVVQPDQMLADDDLQKSLDNLFKDCAQDVRCQKAYSTLPQDWKKLLAGLPQKAQLTHPRLGTQISATITRDDVLGWVTAIIYSPVNSAGLPSAITQAGKGNFNPMLALSGTGNLPNPGSIAYGMHFSVVCAEEYEHQLQATKPSANNDFGDLHNQMYLKVCQQWPRGKVPEGFYTTPVSATPVLLLSGGIDPVTPPWHADRVAKALGPMARHIVLERSGHGMLQQTCLSDVATKFINAKTDQDAQNVDASCVKQIPRPSVWIAPVAPSNSTESAEPVKPSTKTTSSEAQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1E2</accession>
    <name>A0A2S9H1E2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1408</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93799">
        <property type="protein sequence ID" value="PRC93799"/>
        <property type="gene ID" value="S2091_1408"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.428.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011146">
        <property type="entry name" value="HIT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036265">
        <property type="entry name" value="HIT-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026026">
        <property type="entry name" value="HIT_Hint"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01230">
        <property type="entry name" value="HIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000714">
        <property type="entry name" value="HIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54197">
        <property type="entry name" value="SSF54197"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51084">
        <property type="entry name" value="HIT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HIT" evidence="2">
        <location>
            <begin position="3"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Histidine triad motif" evidence="1">
        <location>
            <begin position="91"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="143" mass="16537" checksum="51E0424DF4C59390" modified="2018-07-18" version="1">MMTKCEPCELCSTSGDVIIQSAEWRVILVDDAHYPGFCRVIWTAHVQEMSDLSVSERTMLMNVVWQVELAIREVMRPHKINLASFGNMVPHLHWHVIPRFTDDMHFPNPIWGQVERSVNPGIQQRQLLIPALRSAIVHRLTED</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1E9</accession>
    <name>A0A2S9H1E9_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RES domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1396</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MbcT/ParT/Res family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93787">
        <property type="protein sequence ID" value="PRC93787"/>
        <property type="gene ID" value="S2091_1396"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014914">
        <property type="entry name" value="RES_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08808">
        <property type="entry name" value="RES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00953">
        <property type="entry name" value="RES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RES" evidence="2">
        <location>
            <begin position="20"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="159" mass="17622" checksum="BDA05BFF452F24CE" modified="2018-07-18" version="1">MNSVQLWRISKHTALFRADDLSGEGAKITGGRWNKKSLAVTYSSSTIALATLETLAHIGSEIAARNRFLIAISVPVKLWNKREIITAAELDPSWLAEPPGMFSIEFGSTWLEGRSAALLLVPSIIVPEEFNVLINPKHPDAKKISAKIVRQFIYDPRLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1G0</accession>
    <name>A0A2S9H1G0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Biopolymer transport protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_1434</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Membrane</location>
            <topology evidence="1 6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the exbB/tolQ family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93825">
        <property type="protein sequence ID" value="PRC93825"/>
        <property type="gene ID" value="S2091_1434"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002898">
        <property type="entry name" value="MotA_ExbB_proton_chnl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01618">
        <property type="entry name" value="MotA_ExbB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="15"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="118"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="164"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="domain" description="MotA_ExbB" evidence="8">
        <location>
            <begin position="98"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC93825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="231" mass="24868" checksum="AB17AF803C8332CB" modified="2018-07-18" version="1">MNISYLVELANESGGILYLMLVLLLVALTVIIERTRHLGSMEKGGAKLINMVKKEANHAEQIDLPKKLSHLPHARLFNVLRHDASTSSTPSVPLSGEALIGHLEEAIMHEVPALDRSLWVLDTVITLAPLLGLFGTIIGMFNAFHVLGDAQNGAAQVTGGIAEALVSTACGLLIAMIGLVFFNALHNRVRIVLHQLETLKIMLVNRHPNTVAAATPPVSAQVELIRTPARA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1M9</accession>
    <name>A0A2S9H1M9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1503</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93894">
        <property type="protein sequence ID" value="PRC93894"/>
        <property type="gene ID" value="S2091_1503"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032874">
        <property type="entry name" value="DDE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13610">
        <property type="entry name" value="DDE_Tnp_IS240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_Tnp_IS240" evidence="2">
        <location>
            <begin position="75"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="157"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="169"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="237" mass="28237" checksum="978A2D0A5439891B" modified="2018-07-18" version="1">MNPSKPLYFRHRFPSEIISHCVWLYFRFSLRYRDIEEMMAERGVVVTYETIRNWSKKFGGIYAKRMRSRSKKPNDQWHLDEVYLSINGKTHYLWRAVDQDGEVLDVLGQPRRNKRAAKKFFLKLLKRLQYVPRLIITDKLGSYAAAKAEIMPQIKHTQNKGANNRAENSHQPTRERERQMRRFKSPGHAQRFLATYGVIASFFRPGRHLLSAKNYREIMHRRFAEWSEIVDSGYIAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1Q7</accession>
    <name>A0A2S9H1Q7_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 12">Flagellar biosynthetic protein FliP</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">fliP</name>
        <name evidence="13" type="ORF">S2091_1530</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Plays a role in the flagellum-specific transport system.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Cell membrane</location>
            <topology evidence="12">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="12">Bacterial flagellum basal body</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the FliP/MopC/SpaP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93921">
        <property type="protein sequence ID" value="PRC93921"/>
        <property type="gene ID" value="S2091_1530"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009425">
        <property type="term" value="C:bacterial-type flagellum basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044781">
        <property type="term" value="P:bacterial-type flagellum organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005837">
        <property type="entry name" value="FliP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005838">
        <property type="entry name" value="T3SS_IM_P"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30587">
        <property type="entry name" value="PTHR30587"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30587:SF0">
        <property type="entry name" value="PTHR30587:SF0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00813">
        <property type="entry name" value="FliP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00951">
        <property type="entry name" value="FLGBIOSNFLIP"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01302">
        <property type="entry name" value="TYPE3IMPPROT"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01103">
        <property type="entry name" value="fliP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01060">
        <property type="entry name" value="FLIP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01061">
        <property type="entry name" value="FLIP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0975">Bacterial flagellum</keyword>
    <keyword evidence="7 12" id="KW-1005">Bacterial flagellum biogenesis</keyword>
    <keyword evidence="11 12" id="KW-1006">Bacterial flagellum protein export</keyword>
    <keyword evidence="5 12" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="13" id="KW-0966">Cell projection</keyword>
    <keyword evidence="13" id="KW-0969">Cilium</keyword>
    <keyword evidence="13" id="KW-0282">Flagellum</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 12" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="58"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="100"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="196"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="233"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006257"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU362069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PRC93921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="258" mass="28386" checksum="9C6A4D1B5BD9E4DF" modified="2018-07-18" version="1">MSKRTILAIAVGFLLAMLGMQLHPCFAAPNTFAALPGIDVHVISHGAKNEEVSSALKILLGMTILTLAPAILVSMTSFIRITIVLSMLRHAFGMQETPPNTVLVSLALFLTLFTMMPVINQVNDQAFEPFMNGKIEAGPAFQLGLKPVREFMIRQTREQDLSLMVELAKQPEPKTMDDIPTVELIPAYMLSELRSAFQIGFVIFLPFLLIDLLTSTILMSLGMMMVPPVTISLPVKVLMFVLIDGWNLVVKALVGTFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1Z4</accession>
    <name>A0A2S9H1Z4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1495</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93886">
        <property type="protein sequence ID" value="PRC93886"/>
        <property type="gene ID" value="S2091_1495"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="131" mass="14697" checksum="15DBDE208443A450" modified="2018-07-18" version="1">MITKEELLTAPVDIANLQALEDDLTARARNLIDLLLKSGKLNIASLEFDCTFDDIAAEAQILKSGHYRIKIGRRFSSAILRFAHWSAPRLADLLPPDCQSSRAQTFSIRILDVVHLSPRASSRNLWAPRFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H259</accession>
    <name>A0A2S9H259_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1221</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94048">
        <property type="protein sequence ID" value="PRC94048"/>
        <property type="gene ID" value="S2091_1221"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="70"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="97"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="128" mass="14402" checksum="7A8C4118B03DE491" modified="2018-07-18" version="1">MFRITLRVIAIIQMLLGLAYLIVPNLFLHQLGHSQPAPDLLYPLGMLAARFLAYGAGFWIISSAPEKHVLWIRLMALIQLIDLLVGAFYTVQGVVPVSLSAFPMVNAVWIGLLCFYWKPIQEPVLRRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H298</accession>
    <name>A0A2S9H298_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alpha/beta hydrolase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1246</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94073">
        <property type="protein sequence ID" value="PRC94073"/>
        <property type="gene ID" value="S2091_1246"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015747118" evidence="1">
        <location>
            <begin position="34"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="domain" description="AB hydrolase-1" evidence="2">
        <location>
            <begin position="39"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="259" mass="27509" checksum="A9A97B90AB701FCE" modified="2018-07-18" version="1">MNIAIVPKCAIAAITSATISAVLLAFTASPASAAPINNIVLVHGQFADASGWRPVYDILTKDGYNVTMVQEPLTSLSEDVAATVRVLARQPGQSILVGHSYGGAVITQAGTDPHVAGLVYIAAHAPDEGESTASNKNKIPGKIRTITTPDGFVFVDPAHFHEDFAADLPADQAEFMARSQIPASAKVNTTLITNPAWRVKPSWYMVAKQDRAINPDLERMYAARAHSHTVEVDGAHTIYISKPNEVAAMIEDAAKSLGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2A0</accession>
    <name>A0A2S9H2A0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phage regulatory protein CII (CP76)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1282</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94109">
        <property type="protein sequence ID" value="PRC94109"/>
        <property type="gene ID" value="S2091_1282"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="160" mass="17529" checksum="B0BAA862E335D282" modified="2018-07-18" version="1">MTRRYSDMNQHDALYKIARAYPGGIDALAEKMDISVNVLRNKLAPHIDTHYPSFEELSTIVELCSKAGVKDALMPLHALLSRHGMAAFIVPEPEHITDDDLSQTVCRVMSQVGGVAEAVSSALLDGVITDAEADLIEREFQGALTALGEWRARIRARGGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2C5</accession>
    <name>A0A2S9H2C5_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">50S ribosomal protein L14</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rplN</name>
        <name evidence="6" type="ORF">S2091_1305</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 5">Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the universal ribosomal protein uL14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94132">
        <property type="protein sequence ID" value="PRC94132"/>
        <property type="gene ID" value="S2091_1305"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.150.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01367">
        <property type="entry name" value="Ribosomal_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036853">
        <property type="entry name" value="Ribosomal_L14_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000218">
        <property type="entry name" value="Ribosomal_L14P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005745">
        <property type="entry name" value="Ribosomal_L14P_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019972">
        <property type="entry name" value="Ribosomal_L14P_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11761">
        <property type="entry name" value="PTHR11761"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00238">
        <property type="entry name" value="Ribosomal_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01374">
        <property type="entry name" value="Ribosomal_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50193">
        <property type="entry name" value="SSF50193"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01067">
        <property type="entry name" value="rplN_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00049">
        <property type="entry name" value="RIBOSOMAL_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1 3 4" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 5" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC94132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="122" mass="13304" checksum="D8E10004DE4770FD" modified="2018-07-18" version="1">MIQTESRLEVADNTGAREVLCIKVLGGSKRRYAGIGDVIKVTIKSAAPRGRVKKGEIYNAVVVRTAKGVRRPDGSLVKFDSNAAVLLNAKLEPIGTRIFGPVTRELRTERFMKIVSLAPEVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2F6</accession>
    <name>A0A2S9H2F6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Putative membrane-associated metal-dependent hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_1321</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94148">
        <property type="protein sequence ID" value="PRC94148"/>
        <property type="gene ID" value="S2091_1321"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008484">
        <property type="term" value="F:sulfuric ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016772">
        <property type="term" value="F:transferase activity, transferring phosphorus-containing groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040423">
        <property type="entry name" value="PEA_transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30443">
        <property type="entry name" value="PTHR30443"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="38"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="63"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="112"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="144"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="domain" description="Sulfatase" evidence="8">
        <location>
            <begin position="265"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="168"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="168"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC94148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="612" mass="70567" checksum="C6F4C7ECAED24423" modified="2018-07-18" version="1">MQKQHLLRPAQLYLVCSYLLLSATPFFSLMLGIPVENAATIIGLEIFFWLLLWSVFKRPNYFHWLLLPVFLALPIEIYLRLFFAQGISPHHLGIIFETSPKEAFEFLGRKTWLLALTSIGIFLWWYSLQIVSRKIFIWSHSSRWFCLAVLLFCTMGFVYGEEFGFNTPSHSVTSSPNSTSADEEEDSSPDDATWFQDYTAAYRATMPKLPAWADNDIDKELIGRTWPFGLAIHAADFLYERHYLSILAQKSSTFKFDASSDTTPKTIVIVIGESSRYDRWSLNGFKRDTNPHLKNETNLVSFTDIISAVSATRLSVPIIVSRKPATQSLKAGFSEKSFISAFKEAGYKTYWLSNQMTFGEFDTPISVFAKEADVTQFLNLGGFTNNSSFDQILLEPFQNALTDSAPKKLIVLHTLGNHWNYSHRHPAEFERWKPSLSGVQDPDYNNRDMKEQINNSYDNSILYTDWMLDQVITQLKAQQNISALLYVSDHGQTLYDGSCNLAFHGHNTQYEFHIPAFMWYSNDYLSAYPDKIEQLLRHKKARLSTENIFHSLLDIADVHYPTEQLDRSFVNAQFKPHVRYVDSYGWSNYDNARFKGDCREVIDKNKPLKQEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2H3</accession>
    <name>A0A2S9H2H3_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_1352</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94179">
        <property type="protein sequence ID" value="PRC94179"/>
        <property type="gene ID" value="S2091_1352"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="158"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="8">
        <location>
            <begin position="178"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="7">
        <location>
            <begin position="238"/>
            <end position="438"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC94179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="441" mass="48246" checksum="AF0A3E1C5FAF90C1" modified="2018-07-18" version="1">MIKSLSGRVFLVLLLGIVASVCLTLWLALGERQNSLIKSRESHFLERAEQLVMAIDALPADNRGAFIKMLPRLGIRISLDPDLRGALTSNTANANAMAERIGSEFHVTSLPFVQCPSFGGSGPNAACENFAITLHDGTHLSFVLMPPKMPLPPLTADFYLYLLLFLVCIASLAYLVTRMTIRPLQKLSQAALDLGNDINHPPLEVAGATELKQASSAFNAMQARIRHYIEQRTHMLAAITHDLQTPLTRLRLRIEKVSDHDLRDRLITDLSAMQDMVREGLTLARSMDSSEQRQSVNLDSLIDSAVLDATDAGQPVKLTGETNMSIRAQPQALLRCVNNLIDNALKYGHYANVSVNRDSNNIAMIHIRDGGTGIPEGELEKVFTPFYRLETSRSRDSGGTGLGLTIARNICEQHGGTLTLRNHPEGGLEATLKLPGKALTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H307</accession>
    <name>A0A2S9H307_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0985</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94364">
        <property type="protein sequence ID" value="PRC94364"/>
        <property type="gene ID" value="S2091_0985"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021831">
        <property type="entry name" value="ParD-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11903">
        <property type="entry name" value="ParD_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="73" mass="8116" checksum="1178446E83CBDEBF" modified="2018-07-18" version="1">MSKTMKISESLIEIAKPYAEAQHRSVPKQIEHWARLGKAAEENPELSIVFIQNSILALAEEKAGMATPYSFGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H346</accession>
    <name>A0A2S9H346_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0998</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94377">
        <property type="protein sequence ID" value="PRC94377"/>
        <property type="gene ID" value="S2091_0998"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033399">
        <property type="entry name" value="Put_LolA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011220">
        <property type="entry name" value="UCP028205"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17131">
        <property type="entry name" value="LolA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028205">
        <property type="entry name" value="UCP028205"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015473155" evidence="1">
        <location>
            <begin position="28"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="258" mass="27890" checksum="1E866B7B966B8E18" modified="2018-07-18" version="1">MKTKTTLHISAALVFALASSCWYSATAATATTAAVDPAALVAKLDALRRPSAANLKMVFTLTTSESGAQDTYRYTGLIRRDAGTLVLAEDGDQRGQKYLYTPGGYWLYAPRTRRPMRLTPLQTLRGQASIGDISRLNLADDYSAAFASQSEARIDDHDCWVLTLIAKSPEASYASITLYVNKADQVPVQADLMAGTGRKLKTLKFGGLKKVGGQNLLTTLTYIDAVNTDKRTVQQIDAVESSSTPAAMFQPQALVLEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H376</accession>
    <name>A0A2S9H376_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SnoaL-like domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1028</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94407">
        <property type="protein sequence ID" value="PRC94407"/>
        <property type="gene ID" value="S2091_1028"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037401">
        <property type="entry name" value="SnoaL-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12680">
        <property type="entry name" value="SnoaL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SnoaL-like" evidence="1">
        <location>
            <begin position="8"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="125" mass="14796" checksum="FBAD50D29D5AC869" modified="2018-07-18" version="1">MPTAETIERFIARVEQNAHVEAVQEFYTEDSTMQENQGVSRRGRDAHVENEQKVMARARSLTSECVRPVFVSGDRVVIRWIFKFQWQDGTSTHMEELAYQRWEGERIAEEIFFYDPAQRVPKLRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3H6</accession>
    <name>A0A2S9H3H6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1037</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94416">
        <property type="protein sequence ID" value="PRC94416"/>
        <property type="gene ID" value="S2091_1037"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="168" mass="18592" checksum="2CB207E25318B3EC" modified="2018-07-18" version="1">MDDSAIFKWLINIFVRNSVSANNGSVSIGGDNNAPIIININSNSDSDGTITLIPELIPAKDKVDTAAVQSKRIQFALIFDGEIKDWNSDKINTVLELLQKLTGDMELSFVKIEEGSVRLIFNVLEKDVSTLPINYLRNKLVVSDEYLVGAISLSDLNEIPRLSMFSVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3R8</accession>
    <name>A0A2S9H3R8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0621</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94618">
        <property type="protein sequence ID" value="PRC94618"/>
        <property type="gene ID" value="S2091_0621"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="148" mass="16707" checksum="28DCB64631375597" modified="2018-07-18" version="1">MLGWCYLISPDKIMNVAISFQYPEPSAPKPPRKLNADIVVFTVAFVFMLIAWSGNLTSAKVSSLVMASISQVALLNETVSAALSFHDDERILINNRADGQMIFSQTTHRYLKFNSVVQHYVHQAWGASQLTPFMRGVELPKRRSYFHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3X2</accession>
    <name>A0A2S9H3X2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">PLD-like domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0685</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94682">
        <property type="protein sequence ID" value="PRC94682"/>
        <property type="gene ID" value="S2091_0685"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019637">
        <property type="term" value="P:organophosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025202">
        <property type="entry name" value="PLD-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001736">
        <property type="entry name" value="PLipase_D/transphosphatidylase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13091">
        <property type="entry name" value="PLDc_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00155">
        <property type="entry name" value="PLDc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50035">
        <property type="entry name" value="PLD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015727304" evidence="1">
        <location>
            <begin position="21"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="domain" description="PLD phosphodiesterase" evidence="2">
        <location>
            <begin position="132"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="domain" description="PLD phosphodiesterase" evidence="2">
        <location>
            <begin position="328"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="405" mass="45037" checksum="41DE99A3815D8222" modified="2018-07-18" version="1">MRKLILLATLLISQITIAHAEFSIPGYELVHTVPVETALATPDLREPLQVWSEMFDSAKTEIVLGQFYVASKPGAAFENVINRLAAAGARGVKIRFLMEEKGKSLSDTGTIERLKQIPHLEFRFLDYSKLTGNGIIHAKYMVVDGDTAYVGSQNFDWRSFEHIHETGLRITDHDVVAQIHAIFEQDWQAQELIAQGKKVAALNQHSVAAHDQSAAFLIASPNAYNPDGIGDSEAEIVKLLAEAKSEVRIQLLDYAPLSYGPNHTRPYYAVIDNAIRAALTRGVKVKLMVSNWNTEKPAIHYLKSLSLLPGMEIKIVTLPKAASGFIPFARVIHSKTMSIDGQIAWIGTSNWSGGYLDNSRNMEIVLRNQAMAKRIADLHQQTWDSSYAQAIDMMKDYPKPVKGQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3Y6</accession>
    <name>A0A2S9H3Y6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0691</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94688">
        <property type="protein sequence ID" value="PRC94688"/>
        <property type="gene ID" value="S2091_0691"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="117" mass="13273" checksum="10C99E98EF0921E9" modified="2018-07-18" version="1">MEKHSPSADIYVRFLQLAHALRGLPTLDPLEDRILAFVALAGKAKDRLSVRDMMAQSELGSPAMLHARLKSMREKGWIILTDTDDTRRKQVELSQAAWLHFDKLSKCLMQATQDVNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H493</accession>
    <name>A0A2S9H493_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyltransferase family 28 C-terminal domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0807</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94804">
        <property type="protein sequence ID" value="PRC94804"/>
        <property type="gene ID" value="S2091_0807"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016758">
        <property type="term" value="F:hexosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007235">
        <property type="entry name" value="Glyco_trans_28_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04101">
        <property type="entry name" value="Glyco_tran_28_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_tran_28_C" evidence="2">
        <location>
            <begin position="37"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="153" mass="16755" checksum="96BBA796008C9359" modified="2018-07-18" version="1">MAACEAILTALQSLDAEVICAVPGISSEWKARYNRLRIFDHPVDLQPLLSHADLAITYGAGTIATALLAGVPVMLVPQMAEQYLAGLPLERMGAGLMLREQQSIEQCASLINTLLTMPSYRQAAQAFAQRYANFSTEQACQRLWSAMKVKLEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4C1</accession>
    <name>A0A2S9H4C1_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">RNA polymerase sigma-54 factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">S2091_0794</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the sigma-54 factor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94791">
        <property type="protein sequence ID" value="PRC94791"/>
        <property type="gene ID" value="S2091_0794"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001216">
        <property type="term" value="F:DNA-binding transcription activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000394">
        <property type="entry name" value="RNA_pol_sigma_54"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007046">
        <property type="entry name" value="RNA_pol_sigma_54_core-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007634">
        <property type="entry name" value="RNA_pol_sigma_54_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038709">
        <property type="entry name" value="RpoN_core-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32248">
        <property type="entry name" value="PTHR32248"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00309">
        <property type="entry name" value="Sigma54_AID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04963">
        <property type="entry name" value="Sigma54_CBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04552">
        <property type="entry name" value="Sigma54_DBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000774">
        <property type="entry name" value="RpoN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00045">
        <property type="entry name" value="SIGMA54FCT"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02395">
        <property type="entry name" value="rpoN_sigma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00717">
        <property type="entry name" value="SIGMA54_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00718">
        <property type="entry name" value="SIGMA54_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2 9" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="4 9" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="8 9" id="KW-0804">Transcription</keyword>
    <keyword evidence="5 9" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Sigma54_CBD" evidence="12">
        <location>
            <begin position="144"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma54_DBD" evidence="11">
        <location>
            <begin position="345"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="67"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR000774"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF04552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF04963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PRC94791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="502" mass="56231" checksum="6D0E37E6D7C137D1" modified="2018-07-18" version="1">MKQSLQLRTSQHLALTPQLQQSIRLLQLSTLELHQELEQMLHDNPLLERLDDPMDLAVRLLSDGALNHQPAQSDYSNDNNTNNNSDSSASTANGASEDAHNSSENDSDQSDYQSAQGDESSIWSEANRANQDDDEGRPQLEIVDQSLREYLLDQANLSTRTERDAALLSLLIEALDENGYLDESLEQIHAALPEALGIELDDLSFALSLLQSLEPAGVGARTASECLALQIKRLPRIPLVTRRLALIIVQDHLAQFAQRDFNKIKKALDCDDQDLREAQEVIRQCEPHPGRGFSKDRVDFVAPDVIVIKTRLGWQVQLNQDVMPKLQVNSLYANILKQHKNAASLQTQLQEARWLIKNMRQRFDTILRVSEAIVERQRSFFTHGAVAMRPLVLREIADTLGLHESTISRVTTQKYMLTPHGMFELKYFFGSHVATEAGGEASSTAIRALIKQLIGAENQTTPLSDSKIANMLGEQGMVIARRTVAKYREALKIPPVNLRKTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4D3</accession>
    <name>A0A2S9H4D3_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 7 8">3,4-dihydroxy-2-butanone 4-phosphate synthase</fullName>
            <shortName evidence="7 8">DHBP synthase</shortName>
            <ecNumber evidence="3 7 8">4.1.99.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ribB</name>
        <name evidence="9" type="ORF">S2091_0034</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 7 8">Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7 8">
            <text>D-ribulose 5-phosphate = (2S)-2-hydroxy-3-oxobutyl phosphate + formate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18457"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:58121"/>
            <dbReference type="ChEBI" id="CHEBI:58830"/>
            <dbReference type="EC" id="4.1.99.12"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7 8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="7 8">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="7 8">Binds 2 divalent metal cations per subunit. Magnesium or manganese.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 7 8">Cofactor biosynthesis; riboflavin biosynthesis; 2-hydroxy-3-oxobutyl phosphate from D-ribulose 5-phosphate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7 8">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7 8">Belongs to the DHBP synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.99.12" evidence="3 7 8"/>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94839">
        <property type="protein sequence ID" value="PRC94839"/>
        <property type="gene ID" value="S2091_0034"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00275">
        <property type="reaction ID" value="UER00399"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008686">
        <property type="term" value="F:3,4-dihydroxy-2-butanone-4-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00180">
        <property type="entry name" value="RibB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017945">
        <property type="entry name" value="DHBP_synth_RibB-like_a/b_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000422">
        <property type="entry name" value="DHBP_synthase_RibB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00926">
        <property type="entry name" value="DHBP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55821">
        <property type="entry name" value="SSF55821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00506">
        <property type="entry name" value="ribB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="7 8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7 8" id="KW-0464">Manganese</keyword>
    <keyword evidence="6 7 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7 8" id="KW-0686">Riboflavin biosynthesis</keyword>
    <feature type="region of interest" description="D-ribulose 5-phosphate binding" evidence="7">
        <location>
            <begin position="43"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="D-ribulose 5-phosphate binding" evidence="7">
        <location>
            <begin position="156"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="44"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="48"/>
        </location>
        <ligand>
            <name>D-ribulose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58121"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="159"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="site" description="Essential for catalytic activity" evidence="7">
        <location>
            <position position="142"/>
        </location>
    </feature>
    <feature type="site" description="Essential for catalytic activity" evidence="7">
        <location>
            <position position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00018836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC94839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="220" mass="23683" checksum="41D15A87C7DF8EB1" modified="2018-07-18" version="1">MHSTIQATNSITSLTTPFTQRLERALSDLRLGRPVLLMDDFDRENEADLIFAAEKINTAGMARLIRDGSGIVCLCLTDEKLQQLQLPPMVSSNNSRYGTAFTVSIEASVGVTTGVSAADRVTTIFAAIASDAQPEHLARPGHVFPLRAASGGVLERRGHTEGSVDLAQMAGLMPAAVLCELMNPDGSMAKGDQIKDYAVIHDLVMLSIDELAKYRQQQLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4R2</accession>
    <name>A0A2S9H4R2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Bacterial extracellular solute-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0164</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94969">
        <property type="protein sequence ID" value="PRC94969"/>
        <property type="gene ID" value="S2091_0164"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006059">
        <property type="entry name" value="SBP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01547">
        <property type="entry name" value="SBP_bac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="454" mass="50134" checksum="8331FBCFD5F363A2" modified="2018-07-18" version="1">MQTDKKIMLPTELNKKASTHWICALLLVSTFILLSTTNSIAQTQTVQVLSWWKSTSEHKAVDVLATRLAQENIIWHDALIPSGGIGAGIVLKSRILAGTAPDIAQLKGPLIAEWFDLGLLMEFKALNVNAKESISGSGKWDKSFFPTVTELVRPNGHLVAVPLGIHRINTLIFNRKVFDKYGLRVPENWDDFNIVANKLRREGIIPLAQSSEPWQVVTLFETLLLSESSPDFYRRALVKKDPSAFTDVRFARALLRLRMLKKDMPSPLKEITWVDATRLVAKGDAAMLVMGDFAKAELNAWGLATDVDIGCNAVPNTANYHIYNVDTLVMLSHESISAETADKIAQIAVSPTMQADYNQVKGSVSVLRNADITKMDSCARSSWTVFARGSAVQVPSLAHDMATDKISKDAIIAEIVHFFMDDSIQVAETQRRLGAITRSLPKAKAGKDAQNINR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4T1</accession>
    <name>A0A2S9H4T1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="10">FtsX-like permease family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">S2091_0146</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94951">
        <property type="protein sequence ID" value="PRC94951"/>
        <property type="gene ID" value="S2091_0146"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025857">
        <property type="entry name" value="MacB_PCD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12704">
        <property type="entry name" value="MacB_PCD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="21"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="291"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="338"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="385"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="429"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="675"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="727"/>
            <end position="747"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="759"/>
            <end position="780"/>
        </location>
    </feature>
    <feature type="domain" description="MacB_PCD" evidence="9">
        <location>
            <begin position="20"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="8">
        <location>
            <begin position="322"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="domain" description="MacB_PCD" evidence="9">
        <location>
            <begin position="455"/>
            <end position="640"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF12704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC94951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="797" mass="87702" checksum="BACED665387ED5F3" modified="2018-07-18" version="1">MNLRDFCIGWRLLANEPVYSLVVVFGLALGFAACFLLLGFVRYSFNYDAQVPDKERVYFVKESMTLFSPPFWSNSAKLPLSDVIKKSGQAVATSFVYPIYSVVQVGNVSRKIKLSSVETDFPQIFGIQALEGDLPSALTQPDAIALTMSTAQKIFGDNQALHKTVKIAENLYRVTALLPDPPSNTAQPYEALVGKNTSAWPEVERAKALHDWDNTSSQIYMKLSPHTSPEVLEKMLQKEIDKFGFGRSFKPEELLKLRGGKAIEVRLVALPDGYFDQDLMSDDGEHANKKIVIGLAAVAILILLLAAINYVNLAIVRTLRRQREIGLRKLLGASVNRLVGHFLAEAMLVSMIATALGMLLAWLLLPLFSELMVRKLDTLFTLQNLVFSALFGIIVGLLTGAYPAWIALRVSVSESVAGRGNSETSSGLWLRRILTIMQFSVAMGFTGLTLAIVWQAHYASKINLGFDPEKLVVIDLPDSLINPIDVMFRDKLAHLPGVSEVAASADYPGSPRTKCMNRSHNNAGEPVEMSCQPVSVNFFDVYGVKPLAGRLFNSHIDQVEHSNVVVVNWLAAKALGFHSPEEAIGQIFPVDDNKIIGVVPYIRHQNLRETVQPNYYRLSNALRVLTVRTNGDFDALEKAVTALWVQTFPTDTLRMRRLSDAIAINYADDLRMAKLLAASSLLAIAIAAFGIYVLSAYSVQRRTREIVLRKLYGANGGAIARLLAREYGVLVAISALIGLPIAFVASAKYLAEFVEHAPMGVWPLVGALFVACMVAFVSVLRHALLAIRMPPADALHN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4T9</accession>
    <name>A0A2S9H4T9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0173</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94978">
        <property type="protein sequence ID" value="PRC94978"/>
        <property type="gene ID" value="S2091_0173"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="140" mass="16159" checksum="AC4EE9DF0B66C8BB" modified="2018-07-18" version="1">MDEIKSETQRIALGLIEQTLPKAEWTHEAHLRAGLWHAFHYDDETALNLMRKRICAYNVATGGVNTETSGYHETITRFYLCMIRACLNNIENENSMDELAQKVILKLGDKELPFRYYTRERLFSTEARLAWVAPDIAALP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4V1</accession>
    <name>A0A2S9H4V1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Maltoporin (Phage lambda and maltose receptor)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_0166</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the porin LamB (TC 1.B.3) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94971">
        <property type="protein sequence ID" value="PRC94971"/>
        <property type="gene ID" value="S2091_0166"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046930">
        <property type="term" value="C:pore complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015288">
        <property type="term" value="F:porin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034219">
        <property type="term" value="P:carbohydrate transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003192">
        <property type="entry name" value="Porin_LamB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036998">
        <property type="entry name" value="Porin_LamB_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02264">
        <property type="entry name" value="LamB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0406">Ion transport</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0626">Porin</keyword>
    <keyword evidence="6" id="KW-0675">Receptor</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1134">Transmembrane beta strand</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015510338" evidence="5">
        <location>
            <begin position="29"/>
            <end position="440"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC94971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="440" mass="46362" checksum="7172493DA4E0F552" modified="2018-07-18" version="1">MINQRLKALPFALALALPFIFACGVASADAGHDEDGFHGYLRAGAGASSTGGPQSCFGLGGNTMKYRLGNECDSYFEGGYTKDLATVDDGVIFTGTLWANAWSPNSNFSGATLSLAKAYVEAKNLDFLNGGVAWVGERYYYRPDIHFLDLQFINLNGTGGGIDGIKAGPGKFSYAMFKDNDTNGLDAATGAVTTSRAGLRQNFLYEGLPVNPGGTIDAVATIISATGENNHSGWNLTALHKQEIWGGGNTFAVQYGVGAGTGTGATVNSAGLVVPSESGAGSQGNGRMGNAGSTLLGSDVTRLRVFDELVIQPTKQFSTEFIALYQKDTSDALGSSVWTTIGARPVYAVNRHFKLQMEAGVEHVTFSNGTPSEDLTKVTFAPTIAMGEAYWSRPELRFFVTYGKWNNAATAAVNANNNSGPVYNNGTSGTSAGVQLEAWW</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4Y9</accession>
    <name>A0A2S9H4Y9_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Glutamine--tRNA ligase</fullName>
            <ecNumber evidence="9">6.1.1.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Glutaminyl-tRNA synthetase</fullName>
            <shortName evidence="9">GlnRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">glnS</name>
        <name evidence="13" type="ORF">S2091_0222</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>ATP + L-glutamine + tRNA(Gln) = AMP + diphosphate + L-glutaminyl-tRNA(Gln)</text>
            <dbReference type="Rhea" id="RHEA:20121"/>
            <dbReference type="Rhea" id="RHEA-COMP:9662"/>
            <dbReference type="Rhea" id="RHEA-COMP:9681"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78521"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.18"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="9">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9 10">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.18" evidence="9"/>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95027">
        <property type="protein sequence ID" value="PRC95027"/>
        <property type="gene ID" value="S2091_0222"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004819">
        <property type="term" value="F:glutamine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006425">
        <property type="term" value="P:glutaminyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006424">
        <property type="term" value="P:glutamyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.240.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00126">
        <property type="entry name" value="Gln_tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004514">
        <property type="entry name" value="Gln-tRNA-synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022861">
        <property type="entry name" value="Gln_tRNA_ligase_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000924">
        <property type="entry name" value="Glu/Gln-tRNA-synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020058">
        <property type="entry name" value="Glu/Gln-tRNA-synth_Ib_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020059">
        <property type="entry name" value="Glu/Gln-tRNA-synth_Ib_codon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020061">
        <property type="entry name" value="Glu_tRNA_lig_a-bdl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020056">
        <property type="entry name" value="Rbsml_L25/Gln-tRNA_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011035">
        <property type="entry name" value="Ribosomal_L25/Gln-tRNA_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00749">
        <property type="entry name" value="tRNA-synt_1c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03950">
        <property type="entry name" value="tRNA-synt_1c_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00987">
        <property type="entry name" value="TRNASYNTHGLU"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50715">
        <property type="entry name" value="SSF50715"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00440">
        <property type="entry name" value="glnS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9 10" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="6 9 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 9 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 9 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 9 10" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="tRNA-synt_1c" evidence="11">
        <location>
            <begin position="34"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="domain" description="tRNA-synt_1c_C" evidence="12">
        <location>
            <begin position="363"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'HIGH' region" evidence="9">
        <location>
            <begin position="41"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'KMSKS' region" evidence="9">
        <location>
            <begin position="291"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="42"/>
            <end position="44"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="48"/>
            <end position="54"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="74"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="230"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="249"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="284"/>
            <end position="285"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF03950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PRC95027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="577" mass="65553" checksum="6F518708953D708C" modified="2018-07-18" version="1">MSNEISATPSSNFLRAIIEADLAAGTHTRPGLPKVITRFPPEPNGYLHIGHAKSICLNFGLARDYAGRCHLRFDDTNPEKEDQEYVDTIMDSVRWLGFDWKQDEDAIETEYLHYASDYFDQLYAMAEYLIQTGYAYVDSQSAADMAANRGNFGEAGKNSPFRNRPAAESLDLLRRMKAGEFEDGAHILRAKISEDAMASPNMNMRDPAIYRIRHAHHHRTGDDWCIYPMYDFTHPLSDAIEQITHSICTLEFQDHRPFYDWVIERCAEGGFFKQPVPHQFEFARLNLTYVVTSKRKLRQLVENGTVSGWDDPRMPTIVGIRRRGYTPESIQLFCERIGVTRSDGWIDYSTLEGCLREDLDPKAPRTVAVLRPLKLIIDNFPENVSIACTAPVHPHHPERGNREFNISRELWIEADDFMEVPSKGYFRLFPGNKVRLRYGYVVECTGCDKDADGNVIAVHCTYFPDSKSGTEGSANYKVKGNLHWVSAAHAVATEVRLYDRLFTDANPDAGGKDFMTLLNPNALQVVNAYLEAGIETAQADDKYQFERHGYFVADRVDSTPGKPVFNRVTTLKDSWGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4Z8</accession>
    <name>A0A2S9H4Z8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycerophosphoryl diester phosphodiesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0198</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95003">
        <property type="protein sequence ID" value="PRC95003"/>
        <property type="gene ID" value="S2091_0198"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008081">
        <property type="term" value="F:phosphoric diester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030395">
        <property type="entry name" value="GP_PDE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03009">
        <property type="entry name" value="GDPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="SSF51695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51704">
        <property type="entry name" value="GP_PDE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GP-PDE" evidence="1">
        <location>
            <begin position="5"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC95003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="248" mass="27335" checksum="CCDCA2D024471B0B" modified="2018-07-18" version="1">MWPYPKIIAHRGGGSLAPENTLAAMQCGLNRGFHAVEFDVMLTKDLVPVLLHDEKLGRTVAGQGQVSEMLAQDLFQLEAGSWFAPEFAGCRVPSYTQVLEFCAKNEIWMNVEIKPAAGFDTLTGKITGEITRDFYQKNTQFNAPLPLFSSFSLDALAAVKLAAPLIPRAVLFDQIPANWHEHLRALDAVALHTNQQHLTATLAHEIKQAGYGLSCYTVNEIARAHELLSWGVDALFTDRLDLIGADFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H573</accession>
    <name>A0A2S9H573_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0329</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95134">
        <property type="protein sequence ID" value="PRC95134"/>
        <property type="gene ID" value="S2091_0329"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC95134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="58" mass="6551" checksum="58483BCF67440F2F" modified="2018-07-18" version="1">MSTYLPALIWLLSAFACMFIAKRRHVKPTAIWAMVVTVLGPIAIPLVFFAKPEKYART</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H574</accession>
    <name>A0A2S9H574_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative 3-hydroxylacyl-(Acyl carrier protein) dehydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0340</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95145">
        <property type="protein sequence ID" value="PRC95145"/>
        <property type="gene ID" value="S2091_0340"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01289">
        <property type="entry name" value="FabA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016776">
        <property type="entry name" value="Hydroxyacyl-ACP_deHydtase_prd"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF020565">
        <property type="entry name" value="3Ho_Ac_ACP_DH_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC95145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="156" mass="16815" checksum="36A42F92DFFE247E" modified="2018-07-18" version="1">MSFPEIRSLIPHKDPMVLLDRVIAVDAESLCAELTITPESRFFDGAGVGAWIGIEYMAQAIAAFAGYSAQQREEAVKVGFLLGSRRYECSCSSFLLGSVLQVQVQRVLQNENGLGAFECTISDANDPNADALATATVTVFQPDNASDFLQNSSNES</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5B7</accession>
    <name>A0A2S9H5B7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative flavoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0318</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95123">
        <property type="protein sequence ID" value="PRC95123"/>
        <property type="gene ID" value="S2091_0318"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005025">
        <property type="entry name" value="FMN_Rdtase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03358">
        <property type="entry name" value="FMN_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="SSF52218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FMN_red" evidence="1">
        <location>
            <begin position="1"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC95123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="174" mass="18341" checksum="1036F4BA2DA24D4B" modified="2018-07-18" version="1">MKILAISGSLRAASVNSMLLRAVARLAPADIHVVLYQGLGDLPLFNPDIEASDPAPVADLRAQILSADALLIASPEYAHGMTGVMKNALDWMVGNETFVHKPVALLNAAPRAEYAQAALRETVSVMSARIIEAASITVPIAGSKFSENDIVFHPEISNSLQAALAAMRAAVDLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5B8</accession>
    <name>A0A2S9H5B8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0326</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95131">
        <property type="protein sequence ID" value="PRC95131"/>
        <property type="gene ID" value="S2091_0326"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC95131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="85" mass="9730" checksum="C11098623D0E4098" modified="2018-07-18" version="1">MENKETIPFHQKSYVCIHVFENVRPVLLVSREHGDWCFLCGDDHPEDASIYRAVGIGHVLSRHPDLAEVMDLLPDEEAERSKVCV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5E3</accession>
    <name>A0A2S9H5E3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Alpha-glucosidases family 31 of glycosyl hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_0382</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the glycosyl hydrolase 31 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95187">
        <property type="protein sequence ID" value="PRC95187"/>
        <property type="gene ID" value="S2091_0382"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032513">
        <property type="entry name" value="AGL_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033403">
        <property type="entry name" value="DUF5110"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000322">
        <property type="entry name" value="Glyco_hydro_31"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025887">
        <property type="entry name" value="Glyco_hydro_31_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16338">
        <property type="entry name" value="DUF4968"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17137">
        <property type="entry name" value="DUF5110"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13802">
        <property type="entry name" value="Gal_mutarotas_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01055">
        <property type="entry name" value="Glyco_hydro_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="SSF74650"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015661367" evidence="3">
        <location>
            <begin position="22"/>
            <end position="806"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4968" evidence="5">
        <location>
            <begin position="37"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="Gal_mutarotas_2" evidence="4">
        <location>
            <begin position="147"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="domain" description="DUF5110" evidence="6">
        <location>
            <begin position="685"/>
            <end position="755"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU361185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF16338"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF17137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC95187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="806" mass="91289" checksum="C4A7E884AF88459C" modified="2018-07-18" version="1">MNIKVYIKIAVLLLITPLAIAQNSHRQLDSFVVNNGVLELSTNDGKYLIKPYSDNIVETSFIPTGEVFNPNSHAVIMNPMTPTVIKAKLTATPTAIEFATSGIVVKVDKSPFMISYSYHGKQLTSEKEGYIKDERGETLSFNLDNNEALYGAGARALGMNRRGNRLPLYNKAHYGYEDHSTQMNFSIPLVFSSKMYGIHFDNAPIGYLDLDSKHENTLTYETISGRKTYQLIAGNDWAQLVDNYTKLTGRQPLPPRWAFGNFSSRFGYHSEAEARATVDKFITEKIPLDAIIFDLYWFGKEIKGTMGNLEFDADNFPTPKKMIDDFSYLGVKTILITEPFILTTSKKWDEALQKNILATDEHGQAFTYDFYFGHTGLIDIFNPAGKAWFWSFYKQFTKLGVAGWWGDLGEPEVHPTGLLHQTGSADEMHNIYGHNWAKLIADGYQKDFPEQRPFILMRSGYSGSQRFGMIPWSGDVNRTWGGLQSQPEIALQMGLQGMAYMHSDLGGFAGANLDDELYSRWLQYGVFQPIFRPHAQEEVAAEPVFREQKAKQLAKAAIELRYQLLPYNYTLAFENNQQGLPLMRPLFYEEPQHRALYDVANSYLWGHEFLVKPVLDAGITATSVYFPRSANWFDFYTGQRYLAGTTQAVAVTQDHIPVFVRAGAFIPMIDVIQNTEHYSIKAFNLHYFDDTSVPRSTGKLYDDDGKTPNAFEKDAYSLLQFNSERTPHQLSITLSEKNGVHYQPVNRTVTLIVHNIYVKPGKVLLQSNLKKHAVNYSWDEKCKTLFVSVPLNQKSPAKLVISLSGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5K0</accession>
    <name>A0A2S9H5K0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Exopolyphosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0464</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95269">
        <property type="protein sequence ID" value="PRC95269"/>
        <property type="gene ID" value="S2091_0464"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003695">
        <property type="entry name" value="Ppx_GppA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030673">
        <property type="entry name" value="PyroPPase_GppA_Ppx"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02541">
        <property type="entry name" value="Ppx-GppA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001267">
        <property type="entry name" value="Pyrophosphatase_GppA_Ppx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ppx-GppA" evidence="1">
        <location>
            <begin position="20"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC95269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="485" mass="53821" checksum="B00EBEAB09047872" modified="2018-07-18" version="1">MYAAVDLGSNSFRLHVGRFDGDAMRIVKSAREPIRLGAGLDADGNLTPAAIQSAIVALSRFRTILGQYALDSVRVVATNTMRIAKNAGQFLPELEKAIGYPIEIISGEEEGRLIYMGVAKVLANPAENRLVIDIGGGSTEVIFGHGQEILKVASFSVGTVKQSLSFFPEGRMSRESFEASILSARSHFEDAAPFYQTCNWTRVYGSSGSVRSIAEVMARNKIGDGSLSLTNLEILKDLCIQVGQINQLELAGIKPERTAMVVGGLAILIGVMQELNVVQVQTIEAGLRMGVIWDLHLRATQHDRREQAVLNVSAAFQVEPQRAKFVVELAHIMYEQLKPSADTYKAQLLWAARLHEVGLIVSQTGYHKHGAYLVEYADMQGFTTREQRNMSKMILSQKGNLRKVQESLLDADFAKAVLALRLAVLFMHTRLELSLADVRVRMKSKIELEIKGEWLTQHPTLSYWLEKEHEAWSEINIDFVVRVTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5M6</accession>
    <name>A0A2S9H5M6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Biopolymer transport protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_0472</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the ExbD/TolR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95277">
        <property type="protein sequence ID" value="PRC95277"/>
        <property type="gene ID" value="S2091_0472"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003400">
        <property type="entry name" value="ExbD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30558">
        <property type="entry name" value="PTHR30558"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02472">
        <property type="entry name" value="ExbD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC95277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="139" mass="14954" checksum="6CF50D2D3EDFF5ED" modified="2018-07-18" version="1">MPVSMRSGRTRKLKSEINVVPYIDVMLVLVVILMVAAPMTNPSVVNLPNAGASKQAPTDYLELTIKPDGTASVGKHSQGKAEASTGRADLLERLQHLHETEPDLPLLIAADKEIKYDEVIQMIAGAKKLGISRVGLATK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5N6</accession>
    <name>A0A2S9H5N6_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Transcriptional repressor NrdR</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">nrdR</name>
        <name evidence="11" type="ORF">S2091_0482</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="8">Binds 1 zinc ion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the NrdR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95287">
        <property type="protein sequence ID" value="PRC95287"/>
        <property type="gene ID" value="S2091_0482"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00440">
        <property type="entry name" value="NrdR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005144">
        <property type="entry name" value="ATP-cone_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003796">
        <property type="entry name" value="RNR_NrdR-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30455">
        <property type="entry name" value="PTHR30455"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03477">
        <property type="entry name" value="ATP-cone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00244">
        <property type="entry name" value="TIGR00244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51161">
        <property type="entry name" value="ATP_CONE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 8 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 8" id="KW-0678">Repressor</keyword>
    <keyword evidence="7 8" id="KW-0804">Transcription</keyword>
    <keyword evidence="5 8" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="ATP-cone" evidence="10">
        <location>
            <begin position="49"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="zinc finger region" evidence="8">
        <location>
            <begin position="3"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00440"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC95287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="161" mass="18713" checksum="00A3ECA309AE0698" modified="2018-07-18" version="1">MKCPFCHNDDTQVLDTRVSEEGDAIRRRRRCNKCEKRFTTYERIELAMPYIVKKNGSRCDYDSSKLRASLMLALRKRPVSAPAIDSAIEHIEERLLASGEREILSVQVGELVMHELKRLDKIAYIRFASVYKSFEDVAEFRDMIDEFSPTAHPRKKTSKLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSB5</accession>
    <name>A0A2S9GSB5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Poly-beta-1,6-N-acetyl-D-glucosamine biosynthesis protein PgaD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4689</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000045">
        <property type="protein sequence ID" value="PRC90600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90600">
        <property type="protein sequence ID" value="PRC90600"/>
        <property type="gene ID" value="S2091_4689"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043709">
        <property type="term" value="P:cell adhesion involved in single-species biofilm formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023829">
        <property type="entry name" value="PGA_PgaD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13994">
        <property type="entry name" value="PgaD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03940">
        <property type="entry name" value="PGA_PgaD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="149" mass="17673" checksum="EE53227A353B5209" modified="2018-07-18" version="1">MKTLIFENPELAPLPNRIGWTFFTTFFWIVWVYLWMPLITLVIWALGFNYYDDHFLHNSPSELLDLRNLLVFYLSIIVTLGGSLLLWARTEYMRFRNVHRRTRPLPVAIEDLAEFSGVKPEIMAKLSTVKHMIAHHDEHGKFLYADFED</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSG7</accession>
    <name>A0A2S9GSG7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ParB/RepB/Spo0J family partition protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_4646</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the ParB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000041">
        <property type="protein sequence ID" value="PRC90638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90638">
        <property type="protein sequence ID" value="PRC90638"/>
        <property type="gene ID" value="S2091_4646"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041468">
        <property type="entry name" value="HTH_ParB/Spo0J"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004437">
        <property type="entry name" value="ParB/RepB/Spo0J"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003115">
        <property type="entry name" value="ParB/Sulfiredoxin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036086">
        <property type="entry name" value="ParB/Sulfiredoxin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17762">
        <property type="entry name" value="HTH_ParB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02195">
        <property type="entry name" value="ParBc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00470">
        <property type="entry name" value="ParB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110849">
        <property type="entry name" value="SSF110849"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00180">
        <property type="entry name" value="parB_part"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ParB" evidence="4">
        <location>
            <begin position="35"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00025472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC90638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="295" mass="31854" checksum="211EB96355FF01CB" modified="2018-07-18" version="1">MATKKSKGLGRGLDALLGGAADFADAVPNLVGFPNVLALDLLQAGKYQPRTRMDEGALAELAASIKAQGVMQPILVRPVGEQSSGEIKYEIIAGERRFRASQMAGLTEVPVLVKDVDDQAAAAMALIENIQREDLNPLEEAQGLQRLINDFHFTHEQTAHAVGRSRSAVSNLLRLLNLASPVQTMLMAGDIDMGHARALLVVDGATQIQLANQVVAKRLSVRDTEKLVTNTNDDVKESIPKSREKSRDIARLEEELSDLFATQVQLKMGKKGSGQLIVDFANLDGLDGILSKLRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSP5</accession>
    <name>A0A2S9GSP5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative amidotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_4551</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000037">
        <property type="protein sequence ID" value="PRC90725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90725">
        <property type="protein sequence ID" value="PRC90725"/>
        <property type="gene ID" value="S2091_4551"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002818">
        <property type="entry name" value="DJ-1/PfpI"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01965">
        <property type="entry name" value="DJ-1_PfpI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015755502" evidence="1">
        <location>
            <begin position="21"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="domain" description="DJ-1_PfpI" evidence="2">
        <location>
            <begin position="36"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC90725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="239" mass="25736" checksum="E76725940DA759A8" modified="2018-07-18" version="1">MKRLLLAALTAICTVSATYAADITPHIVPPANRAIKVAFALSEQAEVIDFAGPWEVFGNVMLPGDFKDMQESMPFELYTVGPSQKPIHTSGNRHAGMAITPDYDFLNAPEPDLVVVPAQQGGAALSAWLNKLHAHHKIIMSVCTGAFKLAQAGLLDGKMATTHHSALDKFASQYPKINVVPNVRYVQSDPEIFTSGGLSAGIDLALHMVEAYYGRDVAQATADNMEYQGLGWKTPVTSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GST4</accession>
    <name>A0A2S9GST4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4513</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000036">
        <property type="protein sequence ID" value="PRC90765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90765">
        <property type="protein sequence ID" value="PRC90765"/>
        <property type="gene ID" value="S2091_4513"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC90765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="49" mass="5358" checksum="8F91744EDCBF12C9" modified="2018-07-18" version="1">MKLPSLIRSVCLTLVTVIVVSSLSGCVVVPARGYYGPGYYHSWGYDHRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSX0</accession>
    <name>A0A2S9GSX0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4485</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000035">
        <property type="protein sequence ID" value="PRC90822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90822">
        <property type="protein sequence ID" value="PRC90822"/>
        <property type="gene ID" value="S2091_4485"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021446">
        <property type="entry name" value="DUF3096"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11295">
        <property type="entry name" value="DUF3096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="30"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="50" mass="5362" checksum="EC97D529F7A86FCE" modified="2018-07-18" version="1">MNITLSLVPIVSLIAGILILIIPRLLNLIVAIYLIVIGLVGLFGTGHFLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSZ8</accession>
    <name>A0A2S9GSZ8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Bacteriophage replication A protein (GPA)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_4425</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Possible endonuclease which induces a single-strand cut and initiates DNA replication.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the phage GPA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000034">
        <property type="protein sequence ID" value="PRC90844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90844">
        <property type="protein sequence ID" value="PRC90844"/>
        <property type="gene ID" value="S2091_4425"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008766">
        <property type="entry name" value="Replication_gene_A"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05840">
        <property type="entry name" value="Phage_GPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0235">DNA replication</keyword>
    <keyword evidence="5" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0540">Nuclease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="627"/>
            <end position="655"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009260"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC90844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="655" mass="74533" checksum="444341899B9AA234" modified="2018-07-18" version="1">MNPNLSPHSLIKINAINVSTAAADGNFQCEKTSPIDLQLFNKMFSKGTTMSARRRHELFFETPKFTKEIARIPYKWRKRLMDRAFQKMAWSYWHRIYESIAIDFVRDFAKQYVPAGIDMSQDDNDIIQTAKKAARTVSEGLCAARSDQHVLLIVRAICHEYGIAAPEFEKLSDVVARAIDHRWWRRQLRKSIGRAFEAGNIRLGYVHYRGEPYASNEAVLSRLSQNRRNALAMETTLLQNEHGEQFSIAELAEKTTANKSIRRGELMLRINGFEAIAKENGDHGIFVTWTCPSRFHATHYNGQPNSNYSNATPREANAYLCKVTSLCRSALARLGIGLYGFRIAEPHHDSCPHWHLLLFVRPTDKFKKHHLQDLVSRAIRIMKRYAWRSDRGEAGAFKHRLDVKRIDWSKGSAAGYIAKYVAKNIDGVEQHKTREGYTVAADLNGDVELTPSMRVETWAARWGIRQFQQWGGAPVTVWRELRRIKQDMMNEAPEPMRRAWDAVQKIEGIKRADWAEYLRAQGGAIVPRKKLVITLAKDEKTVIGRYGETIKVTPYGVHCAALIGVVFKSVRHTWTPVNHGGDGAVFDLPRTRVNNCTHPNSALPEIGLNSSPFTVPDQSQVQQNTTNNAMNSRYGPQSKRPPCLVTSKSERAILR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GT29</accession>
    <name>A0A2S9GT29_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4375</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000033">
        <property type="protein sequence ID" value="PRC90882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90882">
        <property type="protein sequence ID" value="PRC90882"/>
        <property type="gene ID" value="S2091_4375"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="146" mass="16415" checksum="F9F6A7017EF89171" modified="2018-07-18" version="1">MNSISFTLRSPWPLALCLFGCVFCGALFVYGLHSPEAHSVGVAKIGVSFLLCLAGIYQFSLTCEVYESVIIVKRVFGWLGQREFKLSQLQNVLLVLNMTNKATAKLEFEDGSCVKLGWYQTNFDPAVRFLRENYPNTFRDKPESTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTH8</accession>
    <name>A0A2S9GTH8_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">3-methyl-2-oxobutanoate hydroxymethyltransferase</fullName>
            <ecNumber evidence="5">2.1.2.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Ketopantoate hydroxymethyltransferase</fullName>
            <shortName evidence="5">KPHMT</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">panB</name>
        <name evidence="9" type="ORF">S2091_4320</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + 3-methyl-2-oxobutanoate + H2O = (6S)-5,6,7,8-tetrahydrofolate + 2-dehydropantoate</text>
            <dbReference type="Rhea" id="RHEA:11824"/>
            <dbReference type="ChEBI" id="CHEBI:11561"/>
            <dbReference type="ChEBI" id="CHEBI:11851"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="EC" id="2.1.2.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5 8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="5 8">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Cofactor biosynthesis; (R)-pantothenate biosynthesis; (R)-pantoate from 3-methyl-2-oxobutanoate: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2 5">Homodecamer; pentamer of dimers.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the PanB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.11" evidence="5"/>
    <dbReference type="EMBL" id="PUGF01000031">
        <property type="protein sequence ID" value="PRC91024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91024">
        <property type="protein sequence ID" value="PRC91024"/>
        <property type="gene ID" value="S2091_4320"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00028">
        <property type="reaction ID" value="UER00003"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003864">
        <property type="term" value="F:3-methyl-2-oxobutanoate hydroxymethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015940">
        <property type="term" value="P:pantothenate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06557">
        <property type="entry name" value="KPHMT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00156">
        <property type="entry name" value="PanB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003700">
        <property type="entry name" value="Pantoate_hydroxy_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_Kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20881">
        <property type="entry name" value="PTHR20881"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02548">
        <property type="entry name" value="Pantoate_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000388">
        <property type="entry name" value="Pantoate_hydroxy_MeTrfase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="SSF51621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00222">
        <property type="entry name" value="panB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3 5" id="KW-0566">Pantothenate biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 9" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Alpha-ketoisovalerate binding" evidence="5 7">
        <location>
            <begin position="54"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5 6">
        <location>
            <position position="190"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5 8">
        <location>
            <position position="54"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 7 8">
        <location>
            <position position="93"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5 7">
        <location>
            <position position="121"/>
        </location>
        <ligand>
            <name>3-methyl-2-oxobutanoate</name>
            <dbReference type="ChEBI" id="CHEBI:11851"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 8">
        <location>
            <position position="123"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011424"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000388-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000388-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000388-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC91024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="272" mass="28711" checksum="AB75F31277F45088" modified="2018-07-18" version="1">MASYLQDSNRKLVTVPSLGALKAQAEKITMLTCYDASFAALMDRCGVDILLIGDSLGMVCQGHNSTLPVSMADMVYHTASVARGNQRCLVVADMPFGSYSTPESAMHNAVQLIQAGAQMVKLEGGAWLAPTIQFLTERSVSVCAHLGLTPQSVHQMGGYKVQGKTTEAADILIKDALAVQAAGASLLVLEAIPKELGQQVTELLAIPTIGIGAGVDCSGQVLVMHDLLGVFPGKKARFVKNFMDGQTNIDDAIKAYVAAVKDGSFPAPEHCF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTJ0</accession>
    <name>A0A2S9GTJ0_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_4230</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="PUGF01000030">
        <property type="protein sequence ID" value="PRC91042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91042">
        <property type="protein sequence ID" value="PRC91042"/>
        <property type="gene ID" value="S2091_4230"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011623">
        <property type="entry name" value="7TMR_DISM_rcpt_extracell_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011622">
        <property type="entry name" value="7TMR_DISM_rcpt_extracell_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07695">
        <property type="entry name" value="7TMR-DISM_7TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07696">
        <property type="entry name" value="7TMR-DISMED2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="177"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="207"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="237"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="270"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="295"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="325"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="357"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="5">
        <location>
            <begin position="423"/>
            <end position="624"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC91042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="633" mass="70918" checksum="9F8FFC9E0B4FB711" modified="2018-07-18" version="1">MPQSRQRLIRIIGFASATLLLYGCLHKANSAPCEVNVLDGTQLPVHLADCVHRINPVEIDKVLPGLQDRTTDNGKWFQIDLLASQNERLKLSLGIPDSYKVQVYLVQNGQVQTVLNLDEASSFSDRPVQHRELFAPLQLSAGPATVYVYDHSHGDIMLFARLSNERQFIFNDTISNLFNGIIYGIMLTLIPVLTLGFSTSRQISFRLYGLMVLANFLFIADIEGYLFAFIWPNSPRWTMLSPGVFGLLSTMAHILFAMNFLRMKSGMPHLYRLHQFLLGLVSLVIALHLMFNLDYAADVVMLFYPMIACYSALQGIRQGIGAASFYFFGALLLLFFPLMLAIVTVTQLNPFPELSILAYPKLVYLLETVMFGAAVISQMRQFNQHQSDQRIVRIAEIEQLLQAERDKTCAMKKASEQQLHLASVSHDIAQPLASLSFAITALSQQAKTNTLTDHMDNTVRYAQTLLKDLLEKARNEHLPPEQIELNATFMQLKQAFAGIAAHKGLRLSVQKSSLCYEGSPILLYRMLTNLLANALRYTQKGRVVLGARRRADGIEIMVCDSGPGITKEIEEVLLQPFRQGVEGEGYGLGLFIVKNLCQQCGYQLRIRSIAGRGSCFSVFIPAQKVVRRSADVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTP2</accession>
    <name>A0A2S9GTP2_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent)</fullName>
            <ecNumber evidence="4">5.4.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">S2091_4246</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:23536"/>
            <dbReference type="ChEBI" id="CHEBI:58225"/>
            <dbReference type="ChEBI" id="CHEBI:58601"/>
            <dbReference type="EC" id="5.4.2.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the phosphohexose mutase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.2.2" evidence="4"/>
    <dbReference type="EMBL" id="PUGF01000030">
        <property type="protein sequence ID" value="PRC91058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91058">
        <property type="protein sequence ID" value="PRC91058"/>
        <property type="gene ID" value="S2091_4246"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004614">
        <property type="term" value="F:phosphoglucomutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05801">
        <property type="entry name" value="PGM_like3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005844">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016055">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I/II/III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005845">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005846">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005843">
        <property type="entry name" value="A-D-PHexomutase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036900">
        <property type="entry name" value="A-D-PHexomutase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016066">
        <property type="entry name" value="A-D-PHexomutase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005841">
        <property type="entry name" value="Alpha-D-phosphohexomutase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045244">
        <property type="entry name" value="PGM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005852">
        <property type="entry name" value="PGM_a-D-Glc-sp"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22573">
        <property type="entry name" value="PTHR22573"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02878">
        <property type="entry name" value="PGM_PMM_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02879">
        <property type="entry name" value="PGM_PMM_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02880">
        <property type="entry name" value="PGM_PMM_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00408">
        <property type="entry name" value="PGM_PMM_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00509">
        <property type="entry name" value="PGMPMM"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53738">
        <property type="entry name" value="SSF53738"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55957">
        <property type="entry name" value="SSF55957"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01132">
        <property type="entry name" value="pgm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00710">
        <property type="entry name" value="PGM_PMM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7 9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PGM_PMM_I" evidence="11">
        <location>
            <begin position="41"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_II" evidence="12">
        <location>
            <begin position="211"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_III" evidence="13">
        <location>
            <begin position="322"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_IV" evidence="10">
        <location>
            <begin position="488"/>
            <end position="540"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="PRC91058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="552" mass="59929" checksum="51FA5AEBD83BA6AE" modified="2018-07-18" version="1">MIISPLAGKSAPIDMLVNVPRLVSAYYTNVPDPSVPSQCVAFGTSGHRGSSLETSFNELHVVAISQAICEYRAKHNITGPLFLGIDTHALSIPASASVVEVLAANGVDVMLAKHDEYTPTPAVSLAIVMYNRGRQFGFADGIVITPSHNPPDNGGFKYNTPNGGPADTSVTDAIELRANELLKKGLSELKRMPYSKALQASTTHYFDYLTSYVNELTQVIDLDAIRDANLRIGIDPLGGAGVHYWGRIGEQYKLNLRVISEEVDPTFRFMTLDWDGRIRMDPSSSYAMQRLIHLQNHYDIAFACDTDHDRHGIVTPTSGLLPPNHYLSVAIDYLFRYRPAWSTTAGVGKTIVSTQMIDHVCVGLGRKMHEVPVGFKWFVDGLSNGSLGFGGEESAGATFLRLDGSTWTTDKDGIVSALLAAEITAKKGRNPGEEYRHLTEKFGDPVAKRVEAVATPIQKKNLSKLSAQQIHSTDLAGQKIISILTEAPGNAAPIGGVKVITADGWFAARPSGTEDIYKIYAESFQGQDHLDRILKEAQEIVDTAISGCNDGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTS0</accession>
    <name>A0A2S9GTS0_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">DNA repair protein RecN</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4 5">Recombination protein N</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_4189</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 5">May be involved in recombinational repair of damaged DNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the RecN family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000029">
        <property type="protein sequence ID" value="PRC91093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91093">
        <property type="protein sequence ID" value="PRC91093"/>
        <property type="gene ID" value="S2091_4189"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004604">
        <property type="entry name" value="DNA_recomb/repair_RecN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003395">
        <property type="entry name" value="RecF/RecN/SMC_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11059">
        <property type="entry name" value="PTHR11059"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02463">
        <property type="entry name" value="SMC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003128">
        <property type="entry name" value="RecN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00634">
        <property type="entry name" value="recN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5" id="KW-0234">DNA repair</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SMC_N" evidence="6">
        <location>
            <begin position="2"/>
            <end position="505"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00033408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR003128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC91093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="548" mass="59822" checksum="333F3D6A3855FC2D" modified="2018-07-18" version="1">MLRTLTIRDFVIVEHIELEFSAGFSVLTGETGAGKSILIDALSLTLGGRGDASMVREGANKADICAEFSSNKVCDAWLSEQELAMDEGMILLRRVIDNAGRSKAFINGVSATAAQLRELGALLVDIHGQHAHQSLLQNDTQRQLLDNHAQLTTQVHEVGGLYKNWNALRQQRTQFEANAKQVLLERERLEWQVSELDKLRTQADEWQEITNEHSRLAHAASLIEGAQYALNAISESEDPILSQIAAINQKLAKLTEYDEDLQAILDTLEPARIHLQEATSSLNDYLSRVELDPERLRIVEDRVEALHSCARKYHVTPEELPTLFKTLSTELAALGEATDLESLLAMEQAALKKYKTSATQLGKARAAAADKLGRAVTDAMQELSMVGGCFEVALTPIEPSLYGTEHIEYMVAGHAGVAARPLAKVASGGELARISLAISVITSSSTATPTLIFDEVDSGIGGGVAEVVGRLLKRLGQDYQVLCVTHLAQVASQADQHFQVSKTSQAEGTVSHIEMLDHKSRVEEIARMIGGLEITATTRKHARELLTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTY5</accession>
    <name>A0A2S9GTY5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4171</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000028">
        <property type="protein sequence ID" value="PRC91170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91170">
        <property type="protein sequence ID" value="PRC91170"/>
        <property type="gene ID" value="S2091_4171"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="177" mass="20604" checksum="AC747B8BBDA331FB" modified="2018-07-18" version="1">MQFTFSLLLFFYSANLLASECEDVYRAHIKSDLLLPYEQFDQTEKKGFRLLAESGCDKEAADLIEEYIKSSKSSKSSLRWHIAQLRATQGDYSAAIKNAMTVLIKKEDFKVDPLRWNDYVLATIAFLERDKEKLIFHRDIVAEGKEEFWGNKLNLKLLDSLILNFDKDYKFATSHIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GU95</accession>
    <name>A0A2S9GU95_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">PPIC-type PPIASE domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_3973</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000025">
        <property type="protein sequence ID" value="PRC91302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91302">
        <property type="protein sequence ID" value="PRC91302"/>
        <property type="gene ID" value="S2091_3973"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000297">
        <property type="entry name" value="PPIase_PpiC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027304">
        <property type="entry name" value="Trigger_fact/SurA_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109998">
        <property type="entry name" value="SSF109998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50198">
        <property type="entry name" value="PPIC_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0697">Rotamase</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015698692" evidence="2">
        <location>
            <begin position="23"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="domain" description="PpiC" evidence="3">
        <location>
            <begin position="131"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC91302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="260" mass="28551" checksum="D52F4CFCB5121458" modified="2018-07-18" version="1">MTFKPAHLLLVLLAFATAPVMAQNVAVVNGTAIPSSRVEEMVKQITSQANAPQDSPDLRLKIKDELITREILIQAADKLGLAKTTEVKAQLEIARQSIMIRALVNDFVKKNPITDAEISAEYEKIKVQAGDKEYHVRHILVATADEAKAIIAKLKAGSTFDELAKQSKDTGSANNGGDLDWATPAAFVKPFSDAMVGLQKGQMTETPVQTQYGFHVIKVDDTRPAKIPTLDELKKQIVEGLEQKKLQAYQEELHKKAVIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUA7</accession>
    <name>A0A2S9GUA7_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF5009 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3962</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000025">
        <property type="protein sequence ID" value="PRC91291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91291">
        <property type="protein sequence ID" value="PRC91291"/>
        <property type="gene ID" value="S2091_3962"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032176">
        <property type="entry name" value="DUF5009"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16401">
        <property type="entry name" value="DUF5009"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="74"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="107"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="130"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="164"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="194"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="222"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="257"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="283"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="313"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="385"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="domain" description="DUF5009" evidence="2">
        <location>
            <begin position="27"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="415" mass="45874" checksum="B64D1C369284A55A" modified="2018-07-18" version="1">MLSANFEESSIATVAAPVRAITKSIQRIRSIDAFRGLTIFIMIFVNELAGVKGVPAWMEHMPATIDGMTFVDVVFPAFLFIVGMSIPFAIAHRRAKGDNFIQLQRHVLARTLGLLVLGVFMVNAEDGYNQAAMPLSINLWSLLFYFAAFLVWHVRLTKSNRLDWTLRLFGVIGLLALALVFRGGDGTAYLAPQWWGILGLIGWAYLIATLCFQLSGGEKLPLVLMLISCVLYYCVGHSFVMQHSVLLPVLFSQGGNAAHASIVLCGVITAQIFFQSHEENSNRWVQASVLAGSLALFAALLRPDWHISKIAATPSWCLYSAAICIALFMLLHYLVEVKQQPVGRFLCRFVEPAANSPLLTYLLPFVVYQLMQICSVSLPDFLRKGSAGIAWSACYALLIMLAAKGLNRLNLRLQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUB7</accession>
    <name>A0A2S9GUB7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative nucleic acid-binding protein contains PIN domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3980</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000025">
        <property type="protein sequence ID" value="PRC91309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91309">
        <property type="protein sequence ID" value="PRC91309"/>
        <property type="gene ID" value="S2091_3980"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002716">
        <property type="entry name" value="PIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002850">
        <property type="entry name" value="PIN_toxin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34610">
        <property type="entry name" value="PTHR34610"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13470">
        <property type="entry name" value="PIN_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="SSF88723"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PINc" evidence="1">
        <location>
            <begin position="12"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="151" mass="16902" checksum="CB751A3A895FF825" modified="2018-07-18" version="1">MIPKPPESRLVLVLDTNVCLDLFVFHDPRWASLLAGLQNGTLTAITKNSCRDEWLTVLHYKQLPITDETRPAISAAFDQLIRCTNPDLSSTIKLPICSDPDDQQFMELARDAHATHLITKDKALLKCAKKVAQLGLFQILSPEKFLGSVEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUG1</accession>
    <name>A0A2S9GUG1_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 10">Ribokinase</fullName>
            <shortName evidence="10">RK</shortName>
            <ecNumber evidence="3 10">2.7.1.15</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">rbsK</name>
        <name evidence="13" type="ORF">S2091_3912</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>ATP + D-ribose = ADP + D-ribose 5-phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13697"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:47013"/>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.15"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="10">Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.</text>
    </comment>
    <comment type="activity regulation">
        <text evidence="10">Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.</text>
    </comment>
    <comment type="pathway">
        <text evidence="10">Carbohydrate metabolism; D-ribose degradation; D-ribose 5-phosphate from beta-D-ribopyranose: step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the carbohydrate kinase pfkB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.15" evidence="3 10"/>
    <dbReference type="EMBL" id="PUGF01000024">
        <property type="protein sequence ID" value="PRC91367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91367">
        <property type="protein sequence ID" value="PRC91367"/>
        <property type="gene ID" value="S2091_3912"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00916">
        <property type="reaction ID" value="UER00889"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004747">
        <property type="term" value="F:ribokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019303">
        <property type="term" value="P:D-ribose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01174">
        <property type="entry name" value="ribokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01987">
        <property type="entry name" value="Ribokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002173">
        <property type="entry name" value="Carboh/pur_kinase_PfkB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011877">
        <property type="entry name" value="D_ribokin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002139">
        <property type="entry name" value="Ribo/fructo_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00990">
        <property type="entry name" value="RIBOKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="SSF53613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02152">
        <property type="entry name" value="D_ribokin_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00584">
        <property type="entry name" value="PFKB_KINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 10 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="8 10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9 10" id="KW-0630">Potassium</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PfkB" evidence="12">
        <location>
            <begin position="6"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="10">
        <location>
            <begin position="14"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="10">
        <location>
            <begin position="42"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="10">
        <location>
            <position position="255"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="143"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="187"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="223"/>
            <end position="228"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="249"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="251"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="254"/>
            <end position="255"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="255"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="285"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="288"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="290"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="294"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005380"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PRC91367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="311" mass="32106" checksum="9988035D175C564E" modified="2018-07-18" version="1">MKPSPNITVVGSINMDLVFRTPRMPAVGETISGHEFVQIKGGKGANQAVAAARQGAVTTLIACVGNDAYGQQSLSGLHADDIVTDFISIINHCATGVAGIFVDDSGHNSIVIAPGANAQLSPSHIDAAKHAISSATLLLCQCETPLATVSAAIQIAHEHGVKVVFNPAPAIPLPDALLAKVSYLIVNETEAEQLSGIKVTNLTTAQTASKNLLNRGAACVLLTMGEQGVCITEQHNSQHIPAIKVTVIDTTAAGDTFVGAFATAIGLGLSTIEAAKQAQYSAALTVTKLGAQSSIPTKAEVERFMVEQLKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUI5</accession>
    <name>A0A2S9GUI5_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RNA pyrophosphohydrolase</fullName>
            <ecNumber evidence="3">3.6.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">(Di)nucleoside polyphosphate hydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rppH</name>
        <name evidence="3" type="synonym">nudH</name>
        <name evidence="7" type="ORF">S2091_3932</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the Nudix hydrolase family. RppH subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.-" evidence="3"/>
    <dbReference type="EMBL" id="PUGF01000024">
        <property type="protein sequence ID" value="PRC91387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91387">
        <property type="protein sequence ID" value="PRC91387"/>
        <property type="gene ID" value="S2091_3932"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016462">
        <property type="term" value="F:pyrophosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd03671">
        <property type="entry name" value="Ap4A_hydrolase_plant_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00298">
        <property type="entry name" value="Nudix_RppH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020476">
        <property type="entry name" value="Nudix_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022927">
        <property type="entry name" value="RppH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00502">
        <property type="entry name" value="NUDIXFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="6">
        <location>
            <begin position="6"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="157"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Nudix box" evidence="3">
        <location>
            <begin position="38"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="174"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC91387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="201" mass="24362" checksum="50C4EC06037E9D0D" modified="2018-07-18" version="1">MLDREGFRPNVGIILLNPTNEVWWGKRVREHSWQFPQGGIKYGETPEQAMFRELEEETGLLPQHVKVIGRTRDWLRYEVPDHFIKRDIRGHYRGQKQIWFLLRMTGRDCDVNLRASNHPEFDAWRWHEYWVPLDMVIEFKREVYQLALQELSRFLSRPEHPKQRQTGRYLRQQQSPHHAEKIDGEDEAIQETTEPRKNQHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUI8</accession>
    <name>A0A2S9GUI8_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Prepilin leader peptidase/N-methyltransferase</fullName>
            <ecNumber evidence="10">2.1.1.-</ecNumber>
            <ecNumber evidence="10">3.4.23.43</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">S2091_3942</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>Typically cleaves a -Gly-|-Phe- bond to release an N-terminal, basic peptide of 5-8 residues from type IV prepilin, and then N-methylates the new N-terminal amino group, the methyl donor being S-adenosyl-L-methionine.</text>
            <dbReference type="EC" id="3.4.23.43"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Cell membrane</location>
            <topology evidence="10">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the peptidase A24 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="10"/>
    <dbReference type="EC" id="3.4.23.43" evidence="10"/>
    <dbReference type="EMBL" id="PUGF01000024">
        <property type="protein sequence ID" value="PRC91397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91397">
        <property type="protein sequence ID" value="PRC91397"/>
        <property type="gene ID" value="S2091_3942"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010627">
        <property type="entry name" value="Pept_A24A_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014032">
        <property type="entry name" value="Peptidase_A24A_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000045">
        <property type="entry name" value="Prepilin_IV_endopep_pep"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06750">
        <property type="entry name" value="DiS_P_DiS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01478">
        <property type="entry name" value="Peptidase_A24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00864">
        <property type="entry name" value="PREPILNPTASE"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="10" id="KW-0645">Protease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 10 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="15"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="114"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="159"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="183"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="220"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="261"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="domain" description="DiS_P_DiS" evidence="13">
        <location>
            <begin position="21"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_A24" evidence="12">
        <location>
            <begin position="137"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF06750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="PRC91397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="288" mass="31425" checksum="9A83686E1019B14A" modified="2018-07-18" version="1">MIFDLYIVAARNLPASLIAGLFGLLIGSFLNVVIYRVPKMMQRDFDNYVAEQSGHELPHQDMFNLMLPRSACPQCGHKISAIENIPVLSFIALRGRCAGCKTPISMRYPLVEMLTALVSFGLVWHFGTGLAGISSLVFGYLLIALALIDFDTQLLPDDLTLPLLWCGLLINTQGVFCSLNSAVLGAAIGYISLWSIYWIFKLVTGKEGMGYGDFKLLAALGAWCGWTVLPVIILCSSLAGAIIGLSLIWFAKRGRDIPMPFGPYLAIAGLVMLPFGQLITQKYLGIVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUW8</accession>
    <name>A0A2S9GUW8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3788</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000022">
        <property type="protein sequence ID" value="PRC91510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91510">
        <property type="protein sequence ID" value="PRC91510"/>
        <property type="gene ID" value="S2091_3788"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015003">
        <property type="entry name" value="DUF1853"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08907">
        <property type="entry name" value="DUF1853"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="316" mass="36295" checksum="56E2AB3C75E5BA81" modified="2018-07-18" version="1">MKLFSPRTPRTPNYQAQFQQRWPHLNHPHVRSLAWLLDSSILLNTSHSRWDNQLAQLPPVNQTINNWLTELEQDSEPLVHFLALHPHTRLGHYAEHLLAFYFKWSGELVAHSVQVRSHRTIGEFDFLLNTASGLQHWEFACKFYLLVAPETKLSNYVGPNLMDNLNDKSHKIMDAQLILGQHPDAQKYLPAQLSAAKALLKGWLFYPATDTDALGEVAPLHCRGLWCRITELQHYDGDCFAILSRLKWLAPAKAYESETMSRSQLHAFLEQQFLSDSRPVLIAHLVPDGEYFVETERIFVVPDAWNLDSSILAISD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GV74</accession>
    <name>A0A2S9GV74_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Lipid A deacylase</fullName>
            <ecNumber evidence="2">3.1.1.77</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">LPS 3-O-deacylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="2">Outer membrane enzyme</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_3748</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>a 3-(acyloxy)acyl derivative of bacterial toxin + H2O = 3-hydroxyacyl derivative of bacterial toxin + a fatty acid + H(+)</text>
            <dbReference type="Rhea" id="RHEA:12032"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28868"/>
            <dbReference type="ChEBI" id="CHEBI:136853"/>
            <dbReference type="ChEBI" id="CHEBI:140675"/>
            <dbReference type="EC" id="3.1.1.77"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell outer membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PagL family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.77" evidence="2"/>
    <dbReference type="EMBL" id="PUGF01000021">
        <property type="protein sequence ID" value="PRC91632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91632">
        <property type="protein sequence ID" value="PRC91632"/>
        <property type="gene ID" value="S2091_3748"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050528">
        <property type="term" value="F:acyloxyacyl hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018550">
        <property type="entry name" value="Lipid-A_deacylase-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011250">
        <property type="entry name" value="OMP/PagP_b-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09411">
        <property type="entry name" value="PagL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029681">
        <property type="entry name" value="PagL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56925">
        <property type="entry name" value="SSF56925"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015535735" description="Lipid A deacylase" evidence="4">
        <location>
            <begin position="23"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="site" description="Critical for activity" evidence="3">
        <location>
            <position position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR029681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR029681-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC91632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="178" mass="20089" checksum="AB98E5B6BCA9EB96" modified="2018-07-18" version="1">MLFPSKHLLCIGLLSISALANAFDGISAEFGEGNQTDLIKIAVQKTLDEQYWQSNGNHFAPYLEASLANWKSDDVQNISGQKQNLYDFGFTPVLRWQKDNRLGWYGEAGIGVHYLTDLYDNNQKKASTKFQFGDHIAIGYVFQNKIEIALKFQHFSNASIKKPNPAMNFALIKLGYAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVC6</accession>
    <name>A0A2S9GVC6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Outer membrane insertion C-terminal signal</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3620</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000020">
        <property type="protein sequence ID" value="PRC91682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91682">
        <property type="protein sequence ID" value="PRC91682"/>
        <property type="gene ID" value="S2091_3620"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011250">
        <property type="entry name" value="OMP/PagP_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005618">
        <property type="entry name" value="OMPW"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36920">
        <property type="entry name" value="PTHR36920"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03922">
        <property type="entry name" value="OmpW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56925">
        <property type="entry name" value="SSF56925"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015702331" evidence="2">
        <location>
            <begin position="27"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="248" mass="25940" checksum="512C7514C368AB04" modified="2018-07-18" version="1">MSSQLTTLYKISALAVAAISSASASAQSAGDTIVSAGWAHIAPQDSSTPLRITSPMSASLPGSGASVDPTNTLGFSVTRFLTDNWATSLDLGIPPTYKLQGTGSLASVGQIGEAKQWAPTLLGKYFFADSNAQFRPFVGVGATYVRYTDISLTQNFQQTVAGTLGLLSQGAIKATDTSAKLSSSWAPVVNVGINYAITKDWSASFSVSYVRLKTTADLTTTTNVGPVLSTTKLTLNPIVTYLSVGYRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVF8</accession>
    <name>A0A2S9GVF8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Folate-binding protein YgfZ</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3584</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000020">
        <property type="protein sequence ID" value="PRC91646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91646">
        <property type="protein sequence ID" value="PRC91646"/>
        <property type="gene ID" value="S2091_3584"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006222">
        <property type="entry name" value="GCV_T_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045179">
        <property type="entry name" value="YgfZ/GcvT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017703">
        <property type="entry name" value="YgfZ/GcvT_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22602">
        <property type="entry name" value="PTHR22602"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01571">
        <property type="entry name" value="GCV_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03317">
        <property type="entry name" value="ygfZ_signature"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GCV_T" evidence="1">
        <location>
            <begin position="16"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="337" mass="36596" checksum="92083E13920A3B0F" modified="2018-07-18" version="1">MHALTLPKPLNNSLSGFCKLSQFALITASGVDAANFLQSQLTNDIKSLAANRACLAGYCTPKGRLLASMLIWKTTESATDTITIEVPAELQEALQKRLQMFVMRAQVKLHHSSPTSAILGILGADAAAQLAEWFPTLPVAPYELVNNESGTLLRLADAQGIARYQWITTKEFAEQAWPALLAISPSLPEHVWGWSEIHAGIPHISLATQEKFVPQMINYELIGGVNFKKGCYPGQEIVARSQYLGKQKRRMVLAQINSATVHSGMEVFASDDLSQPCGMVVNAQPNGADGSDCLIEIKTAYLKDATVQLSSGEVCNWLPMPYPLPDDTLASTDQPTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVM0</accession>
    <name>A0A2S9GVM0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Acyl-coenzyme A synthetase/AMP-(Fatty) acid ligase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3515</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000019">
        <property type="protein sequence ID" value="PRC91760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91760">
        <property type="protein sequence ID" value="PRC91760"/>
        <property type="gene ID" value="S2091_3515"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-binding" evidence="1">
        <location>
            <begin position="54"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding_C" evidence="2">
        <location>
            <begin position="458"/>
            <end position="540"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="548" mass="59778" checksum="60C5E0AB05F3AD0A" modified="2018-07-18" version="1">MSTVKLDQGLDIIRDNFASENLPPRSEWPELLFDLSHLQYPAQLNCAQELLSKVALHPDKAALIGADATLSYAQLQAQVNQISHVLRDQMQLIPGNRVLLRGANNPMLVACILAVWQVGCIAVPSMPMLRSRELGVMLEQAQISAALCSVDLKDELLSAQEQHPVLQKIIYYGALDQNSKDGGLEELLAKKSTEFTTFATSVEDVCLIGFTSGTTGKPKATVHFHRDVMAICDCFPVSTLRSNADDIFIGTPPLAFTFGLGGLALFPLRVGASAVLLEKYSPETLLQAIQNYRASICFTAPTFYRHMAVLAHQFDLSSLRKTVSAGEALPIATRAAWQQATGLRMIDGIGATEMLHIFISAADDEVRPGATGKPIPGYQACILDDDGQPVAAGVVGRLAVKGPTGCRYLADPRQANYVCNGWNVTGDAYEMDDDGYFWYRARTDDMIISAGYNIAAPEVEEVLLQHPAVAECAVIGCADEERGQIVKAYIVLCPEFKGDAKSDANMVAGLQSYVKEIIAPYKYPRAIEFKDSLPRTETGKLQRFKLRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVR5</accession>
    <name>A0A2S9GVR5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3568</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000019">
        <property type="protein sequence ID" value="PRC91813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91813">
        <property type="protein sequence ID" value="PRC91813"/>
        <property type="gene ID" value="S2091_3568"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="83" mass="9527" checksum="2AB62ADB2E31E0AC" modified="2018-07-18" version="1">MELIEPDEMRKFQAILKNHQITFTDFSFSEIDTTDPKTDEIYALQGFLNVTRKSNGLSKEYLIGDGTAWVSQFQKDLDEGAFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVT8</accession>
    <name>A0A2S9GVT8_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Flagellar hook-associated protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_3377</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Bacterial flagellum</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the flagella basal body rod proteins family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000018">
        <property type="protein sequence ID" value="PRC91821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91821">
        <property type="protein sequence ID" value="PRC91821"/>
        <property type="gene ID" value="S2091_3377"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009424">
        <property type="term" value="C:bacterial-type flagellum hook"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044780">
        <property type="term" value="P:bacterial-type flagellum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001444">
        <property type="entry name" value="Flag_bb_rod_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010930">
        <property type="entry name" value="Flg_bb/hook_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002371">
        <property type="entry name" value="FlgK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30033">
        <property type="entry name" value="PTHR30033"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00460">
        <property type="entry name" value="Flg_bb_rod"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06429">
        <property type="entry name" value="Flg_bbr_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01005">
        <property type="entry name" value="FLGHOOKAP1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02492">
        <property type="entry name" value="flgK_ends"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0975">Bacterial flagellum</keyword>
    <keyword evidence="9" id="KW-0966">Cell projection</keyword>
    <keyword evidence="9" id="KW-0969">Cilium</keyword>
    <keyword evidence="9" id="KW-0282">Flagellum</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <feature type="domain" description="Flg_bb_rod" evidence="7">
        <location>
            <begin position="6"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="domain" description="Flg_bbr_C" evidence="8">
        <location>
            <begin position="595"/>
            <end position="655"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF06429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC91821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="658" mass="67004" checksum="381B10512FE968A4" modified="2018-07-18" version="1">MGVNILQIGTSGLQAAEIGIATTGQNISNANTPGYNQEVTQQATSPEQGFSFGFLGQGTQVDTITRDFNALLAQQINTTQSASSQITSYSNQITPIDNMIANPSAGLSPVLQSFFSSLQNLSSNPAGVASLQTAMSGAQTLVAQFQSLQTELSQSSSNVNSQISDEVNTINTDAQQLATVNSAIQVAYGTANNQPPNALLDQRDALVNSLSKETQVTVVPVGNQYNVFIGNGQPLVVGATASTLQTVPSAANPANLEVAYTINGNAVPIGESSLPGGTLGGLFAFRTNSLEPIQNALGQVAIVLGSNLNAQNELGQTINGTMGQALFTVASPVVNANTGNTGNAVISAAITNPSALTADNYSLTYNGGNYSITDTTTNTVKSTFAAFPAVPTAGVNVIDGVTYTLTSGAMAAGDSVLVSPTFGGAAGFGLATTDPTQIASAAPIATSSATTNTGTGVMTPGSVTTGYTPAAVAPPITLTYAALTNSLSGFPVGSTVVTTVNGVSTTYAGYVAGTPIPYTSGMSMTFNNMAVGLSGIPANGDTYTVGPNTNGKGDNRNVLLMNALLTQNTMNNGTTTYQGAYAQMVNSVGNTTSQLTTTGTTETNLLTAAQQQQQSVSGVNLDQETVNLLQYQQVYEACGKVIQVASQNFSTLLSLNGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVZ4</accession>
    <name>A0A2S9GVZ4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Amino acid transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_3451</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000018">
        <property type="protein sequence ID" value="PRC91895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91895">
        <property type="protein sequence ID" value="PRC91895"/>
        <property type="gene ID" value="S2091_3451"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="30"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="62"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="103"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="151"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="185"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="214"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="255"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="301"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="358"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="380"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="412"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="437"/>
            <end position="455"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC91895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="467" mass="49897" checksum="55BCC1D586717745" modified="2018-07-18" version="1">MARMLRTKPIEALLSHEEESGGSLRRNITLFQLTMLGVGATIGTGIFVILGDAVPKAGPGVILSFIIAGITAGLTALCYAELASTIPASGSSYSYTYATMGEMVAYLVGWCLLLEYGISASAIAVGWGQYLNELSFDVLGMRMPDAIANPPGVNGGIFNLPAVILVFMCCALLMRGAKESARANAIMVVIKIAVLIMFILIGMTAFHSTNLHPFMPMGISGVGAAASSIFFSYIGIDAISTASEEVQNPKRTLPLAILFSLAIVTTLYVLVALVGVGTQPYTEFSGNEAGLVHILRRITGAAWPAMILSMGAIISIFSITLVVLYGQTRILFAMARDGMLPKIFAKVDPRTQTPRQNTIIVGTLVAIAAALVPLDVLADLTSMGTLVAFGIVSIGVIILRRTRPELVRGFKVPLFPLVPILSVLFCAYLIVGLPTHTFILFAAWLSFALIFYFCYSMHHSKLEKKAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWG6</accession>
    <name>A0A2S9GWG6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">GGDEF: diguanylate cyclase (GGDEF) domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_3198</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000016">
        <property type="protein sequence ID" value="PRC92063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92063">
        <property type="protein sequence ID" value="PRC92063"/>
        <property type="gene ID" value="S2091_3198"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01948">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001633">
        <property type="entry name" value="EAL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035919">
        <property type="entry name" value="EAL_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00563">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00052">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141868">
        <property type="entry name" value="SSF141868"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50883">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="61"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="92"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="138"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="167"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="3">
        <location>
            <begin position="248"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="domain" description="EAL" evidence="2">
        <location>
            <begin position="388"/>
            <end position="641"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC92063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="657" mass="74160" checksum="6C03DB31F5D6C797" modified="2018-07-18" version="1">MSIASQARHIFHILVDVFAFKIEDKIAIEKRIRNVTAVATIGLFFGFVFALFNLFTPNMALLGLIELGSVIFLMGPATILGRNPDFVGFAEALVLLAMLCIVMGLIAFGGVEGTGLFWVYTAPFLAFFLKGQHLGWRYSLVLLGIVTAYFIGTSQLQHVFYRHSPVVSAQFIISLVFYILIAAAFNQLRSRFEEQLQKQVVIKTADAQKLLDQLQLLASRDSLTKLPNKVTLVDILKQQIDETSNPDSVLVVCILRLERMLEMSNILGIAKADQLILKVVEYLARFTEAKGTLAHTHRDEFVVTYPTDRASFNDEGLERFIAERQISVEIQGYVIYCEFTLGLAIYPDHAKDPQLLLDKAQQAMLQAHKNGNQWSIYDSKQEQAFVRHHLLFGKLRAALMQQHLRVHYQPQIDLVTGLIVGAEALLRWQDPVEGYISPLEFIPVAEESGLIRPLTTWLVDVCVRECSEWRKQGFELHVSINLSALNLLDPELINVLMTALKKYNLAAFNITLEITESCFMSSPERALEVIQRLHETGFRLAIDDFGTGYSSLSYLKNLPIHELKIDQSFVRKLLQNKGDQAIVSSTVDLAHNFGLVVVAEGIEDEPTSHWLHTRGCDIGQGYFFAKPMPSDAFLKLLFTNLLDHKPEKEINEDYPTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWP2</accession>
    <name>A0A2S9GWP2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3061</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92145">
        <property type="protein sequence ID" value="PRC92145"/>
        <property type="gene ID" value="S2091_3061"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="94"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="121"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="183"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="210"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="260"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="332"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="358"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="411"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="433"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="465"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="496"/>
            <end position="515"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="520" mass="56025" checksum="46F5C0D5D0228FFE" modified="2018-07-18" version="1">MNATTIKILILTEARLRLRRLSTLVTLLLVAALAWLMLADQSSGNTFIAVQNAKVLYTSSALALGSATMFSLVFGLAGFYLVRGRISEDVRSGASGVIASSTISNALFLLCRWLGGVGYLVVLAGAFMLSIMACHLFRGVGAINVFVYLETYGVILLPLIFFSVSCAVLFDGIAPLMGKLGDVIYFFLWIAQISILGSSEANATHQITSIMLFDFSGIVMTMQSLFAYLHTSNISMGYASFDPKLVPVTLTNDLWSGPMLLMRFASAAVASLILLPSFFLFHRYSPDKVKVSHARERRSPIAVLNQVLRPLSGLVQPLFPMAARLPGILGQALADVALTLTSSPAAILALILVLLSSIFVNLTMLPSVLLAALAYWGILVSDISTRDYMTGCEDMTGVVAGGAKQRYLRQLVATFMLGLLFTISIALRLAFHAPLLACALLVGLFSLSALASLLGRTSRSSRTFLALFLFWLYVATQVSNVPIIDVAGFNAVANSISITTQMIIAITALIFGYSYNRLAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWP3</accession>
    <name>A0A2S9GWP3_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5 6">Elongation factor Ts</fullName>
            <shortName evidence="5">EF-Ts</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">tsf</name>
        <name evidence="9" type="ORF">S2091_3063</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 6">Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5 7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the EF-Ts family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92147">
        <property type="protein sequence ID" value="PRC92147"/>
        <property type="gene ID" value="S2091_3063"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00050">
        <property type="entry name" value="EF_Ts"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036402">
        <property type="entry name" value="EF-Ts_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001816">
        <property type="entry name" value="Transl_elong_EFTs/EF1B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014039">
        <property type="entry name" value="Transl_elong_EFTs/EF1B_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018101">
        <property type="entry name" value="Transl_elong_Ts_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11741">
        <property type="entry name" value="PTHR11741"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00889">
        <property type="entry name" value="EF_TS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="SSF46934"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54713">
        <property type="entry name" value="SSF54713"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00116">
        <property type="entry name" value="tsf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01127">
        <property type="entry name" value="EF_TS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5 6" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="4 5 6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EF_TS" evidence="8">
        <location>
            <begin position="71"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Involved in Mg(2+) ion dislocation from EF-Tu" evidence="5">
        <location>
            <begin position="80"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC92147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="293" mass="31199" checksum="CB443A57F9257733" modified="2018-07-18" version="1">MAAITAAMVGELRAKTDAPMMECKKALTEAEGNMERAEEILRVKLGGKASKAASRVTAEGVIAAYVAGNVGALIEINCETDFVTKNDEFLALANACVKLVAEHNPADVAALSALPLGESTVEGLRTTLIGRIGENMSIRRFVRFESTSKISTYLHGTRIGVIVDFDGANEQVGKDVAMHIAAMKPVSLSIEQVPAELIEKERSVATLKAAESGKPADIAAKMIEGSVQKFLKEVSLLNQPFVKSDKQTVEQMLKAEASTVKAFQMYVVGEGIEKKQDDFAAEVAAQVAAAQKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWR9</accession>
    <name>A0A2S9GWR9_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Uridylate kinase</fullName>
            <shortName evidence="6">UK</shortName>
            <ecNumber evidence="6">2.7.4.22</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Uridine monophosphate kinase</fullName>
            <shortName evidence="6">UMP kinase</shortName>
            <shortName evidence="6">UMPK</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">pyrH</name>
        <name evidence="8" type="ORF">S2091_3064</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the reversible phosphorylation of UMP to UDP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>ATP + UMP = ADP + UDP</text>
            <dbReference type="Rhea" id="RHEA:24400"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.22"/>
        </reaction>
    </comment>
    <comment type="activity regulation">
        <text evidence="6">Inhibited by UTP.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 6">Pyrimidine metabolism; CTP biosynthesis via de novo pathway; UDP from UMP (UMPK route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homohexamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 6">Belongs to the UMP kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.22" evidence="6"/>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92148">
        <property type="protein sequence ID" value="PRC92148"/>
        <property type="gene ID" value="S2091_3064"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00159">
        <property type="reaction ID" value="UER00275"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033862">
        <property type="term" value="F:UMP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044210">
        <property type="term" value="P:'de novo' CTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04254">
        <property type="entry name" value="AAK_UMPK-PyrH-Ec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01220_B">
        <property type="entry name" value="PyrH_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036393">
        <property type="entry name" value="AceGlu_kinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001048">
        <property type="entry name" value="Asp/Glu/Uridylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011817">
        <property type="entry name" value="Uridylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015963">
        <property type="entry name" value="Uridylate_kinase_bac"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00696">
        <property type="entry name" value="AA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005650">
        <property type="entry name" value="Uridylate_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53633">
        <property type="entry name" value="SSF53633"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02075">
        <property type="entry name" value="pyrH_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 6" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AA_kinase" evidence="7">
        <location>
            <begin position="8"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="13"/>
            <end position="16"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="55"/>
        </location>
        <ligand>
            <name>UMP</name>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="56"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="60"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="75"/>
        </location>
        <ligand>
            <name>UMP</name>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="136"/>
            <end position="143"/>
        </location>
        <ligand>
            <name>UMP</name>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="163"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="169"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="172"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC92148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="239" mass="25446" checksum="9873E6B6DAA8D4BA" modified="2018-07-18" version="1">MLKKSAYKRVLLKLSGEALMGDDAYGINRATIERMVADVAEIKALGIELAIVIGGGNIFRGVAPGAEGMDRATADYMGMLATVMNSLALADAMRQAGITARVMSAIAIDQVVEPYVRPKALQYLEEGKVVVFAAGTGNPFFTTDTAAALRGAEIGAEIVLKATKVDGVYSADPNKDSNAVRYSTISFDEALSRQLQVMDATAFALCRDRNLPIKVFSIVKPGALKRVIMGEDEGTLVHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWV2</accession>
    <name>A0A2S9GWV2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3119</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92203">
        <property type="protein sequence ID" value="PRC92203"/>
        <property type="gene ID" value="S2091_3119"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018680">
        <property type="entry name" value="DUF2164"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09932">
        <property type="entry name" value="DUF2164"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="82" mass="9609" checksum="D84B2C7B3389DED3" modified="2018-07-18" version="1">MAIKLSKENEERLLGSIQRFFKEHMDEEIGSLKSTLFLDFCLRELGPSIYNQAIADAQSHMQDRVAEMDISCHEQEISYWKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWW2</accession>
    <name>A0A2S9GWW2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3107</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92191">
        <property type="protein sequence ID" value="PRC92191"/>
        <property type="gene ID" value="S2091_3107"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005654">
        <property type="entry name" value="ATPase_AFG1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12169">
        <property type="entry name" value="PTHR12169"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03969">
        <property type="entry name" value="AFG1_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="365" mass="42040" checksum="9D6D56B4B133FE64" modified="2018-07-18" version="1">MNVVEFYKHALAERGFTADEAQFRAVERLQVAFDEWLAYKNRRTNKLMRMLNPPEIPRGVYMWGGVGRGKSFLMDSFYNVVPLQRKTRIHFHEFMRGVHQQLDELKGVANPLDIVAAKIAKKYRLICFDEFHISDVADAMIMFNLLTGLFNHGVSFIMTSNYQPDTLYPDGLHRDRLLPTIKLLNERLDVMNVDSGNDYRKRALEQVEVYLTPLNSATDAALRLAYKKIAEVADEDARLRIESREIHALRRAGGIIWFDFATLCGGPRSQNDYLEIASQFHTVILSGIPRLSAAMSSEARRFTWLIDVFYDHKIKLIMSAQVAADELYTEGTLSNEFHRTVSRIIEMQSREYMDSQTRAATDELV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GX56</accession>
    <name>A0A2S9GX56_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Zinc-binding dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2963</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92304">
        <property type="protein sequence ID" value="PRC92304"/>
        <property type="gene ID" value="S2091_2963"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PKS_ER" evidence="1">
        <location>
            <begin position="10"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="257" mass="27463" checksum="55EC288FDC0000B6" modified="2018-07-18" version="1">MLAVQYQAYGGYEENRVDDLPRPQPVDGEVLLEMRTVDINPLDNTFRSGHFYAATADNLPRIGGQNGVGVVIETKSPAFAVGDRVFVSGKGFGLAADGTWRQFIAMPAAGLKRVPANIDDDHAAAFLAGAGYPIGYLALTEFAHFKPEKTVLAPGIGGAVGMETVQIARRLGASMAIFTASTTHKTELARAAGYEHVIDLSREKLQDGVMRLTNGNLAAGGLQPTIANVFPLSEAADAVRHLIEDRPFDRVLMRANG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GX92</accession>
    <name>A0A2S9GX92_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Probable Fe(2+)-trafficking protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2987</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the Fe(2+)-trafficking protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92328">
        <property type="protein sequence ID" value="PRC92328"/>
        <property type="gene ID" value="S2091_2987"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3880.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00686">
        <property type="entry name" value="Fe_traffic_YggX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007457">
        <property type="entry name" value="Fe_traffick_prot_YggX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036766">
        <property type="entry name" value="Fe_traffick_prot_YggX_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36965">
        <property type="entry name" value="PTHR36965"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04362">
        <property type="entry name" value="Iron_traffic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029827">
        <property type="entry name" value="Fe_traffic_YggX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111148">
        <property type="entry name" value="SSF111148"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="90" mass="10215" checksum="A657FE1F34B42538" modified="2018-07-18" version="1">MSRMIQCIKLNKEAEGLDFPPYPGELGKKIYESVSKEAWAAWLKHQTMLVNENRLNLADVRARKYLATQMEKHFFGDGADAAVGYVPPTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXB9</accession>
    <name>A0A2S9GXB9_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Guanylate kinase</fullName>
            <ecNumber evidence="2 9">2.7.4.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8 9">GMP kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">gmk</name>
        <name evidence="11" type="ORF">S2091_3018</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Essential for recycling GMP and indirectly, cGMP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ATP + GMP = ADP + GDP</text>
            <dbReference type="Rhea" id="RHEA:20780"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.8"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the guanylate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.8" evidence="2 9"/>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92359">
        <property type="protein sequence ID" value="PRC92359"/>
        <property type="gene ID" value="S2091_3018"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004385">
        <property type="term" value="F:guanylate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00328">
        <property type="entry name" value="Guanylate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008145">
        <property type="entry name" value="GK/Ca_channel_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008144">
        <property type="entry name" value="Guanylate_kin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017665">
        <property type="entry name" value="Guanylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020590">
        <property type="entry name" value="Guanylate_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00625">
        <property type="entry name" value="Guanylate_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00072">
        <property type="entry name" value="GuKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03263">
        <property type="entry name" value="guanyl_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00856">
        <property type="entry name" value="GUANYLATE_KINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50052">
        <property type="entry name" value="GUANYLATE_KINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 9 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Guanylate kinase-like" evidence="10">
        <location>
            <begin position="9"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="16"/>
            <end position="23"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00030128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC92359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="216" mass="23980" checksum="37977334690DBD6A" modified="2018-07-18" version="1">MSHLNTHAGSLFMVAAPSGAGKSTLVNALLAKESDLRLSISYTTRPPRPGEVDGREYHFTTVEDFLARKDNKEFLECAEVHGNYYGTSRILINQHMQAGTDMLLEIDWQGAQQVKAQFPHSVGIFILPPSIDALEQRLKKRGQDSEQVITRRLLAAGGEIAHAPEFEYVIINQEFEVALSELVAIVKATRCRFNQQAARNSALFAQFGIHANLSQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXM2</accession>
    <name>A0A2S9GXM2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">KaiC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2833</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92458">
        <property type="protein sequence ID" value="PRC92458"/>
        <property type="gene ID" value="S2091_2833"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030665">
        <property type="entry name" value="KaiC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014774">
        <property type="entry name" value="KaiC-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010624">
        <property type="entry name" value="KaiC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06745">
        <property type="entry name" value="ATPase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039117">
        <property type="entry name" value="KaiC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51146">
        <property type="entry name" value="KAIC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="KaiC" evidence="2">
        <location>
            <begin position="8"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="domain" description="KaiC" evidence="2">
        <location>
            <begin position="252"/>
            <end position="481"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="497" mass="54395" checksum="BFDEADDEB0AB13EE" modified="2018-07-18" version="1">MNEKVKIRRLKTGVPGLDNLMGGGLPEFSFNLIAGSPGSGKTTLAHQIMFALATPASPALFFTVLGEPTLKMLRYQQQFPFFDPEKIKKSIHYFNLSTELVNGNFDRVLERIIEEVKNYSPGLVFVDSFRSIVHSVMNKTEGEAALERFVQQLGVHLATWQATSFLIGEYLIPESESSPVFTIADGILWLAQNLHRNSLVRKIQVVKIRGQAQAPGLHTFRINNDGVQIYPRAIVNAGAATDSTTGVPAEEERVTMGVPGLDDMLGGGLPTGYSLLVVGPSGSGKTILATEFIAEGARKGETSVIAAFEKSPSQLLSNKLNALIKAGQVGVIETRALDLSIDQTLHDLIAMITRMKAKRVVIDSLSGFELALAPEFQEDFRGSLYRMIAELTGLGVTIFMTSELEDRYTDLRFSPFGSAFLADAIIVQRYIEIEGEFKRAISVVKVRGSQHSKQIRLFDVTDDGIMLGAPLSDYAGIMTGRPRLTSELVQPDGGKRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GY33</accession>
    <name>A0A2S9GY33_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2676</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92621">
        <property type="protein sequence ID" value="PRC92621"/>
        <property type="gene ID" value="S2091_2676"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="133" mass="14334" checksum="C763159EB7C860BA" modified="2018-07-18" version="1">MIAQAYAEKKIATKFEPIPTCAHCGKISSAHFEDGHCEPVAPEVVSTLTDIEIRNAYETTPSHLSGYRGVANAAAKAERARIAALPINTSLTDDKLHEIYISNRSTNVDDMNEVRACANAAISQFQCELGGAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GY95</accession>
    <name>A0A2S9GY95_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2744</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92689">
        <property type="protein sequence ID" value="PRC92689"/>
        <property type="gene ID" value="S2091_2744"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="75" mass="7637" checksum="4B1634D653F184D8" modified="2018-07-18" version="1">MNQVVKDILTGIDGQSFAIVKVLGFAVVLVFILIEVAAFITGKPFDGQAYGIGAGAAIAAMGGAIKLSETSEPKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYK1</accession>
    <name>A0A2S9GYK1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ABC-type branched-chain amino acid transport systems periplasmic component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2532</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92802">
        <property type="protein sequence ID" value="PRC92802"/>
        <property type="gene ID" value="S2091_2532"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028081">
        <property type="entry name" value="Leu-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13458">
        <property type="entry name" value="Peripla_BP_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peripla_BP_6" evidence="1">
        <location>
            <begin position="47"/>
            <end position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="394" mass="43002" checksum="84A0CF2BA53C470B" modified="2018-07-18" version="1">MRKFFLVLLLILLSLVGCDKLNLAQQRAEHLAQPGKDITIAVAWPMNSAKTSLLNGIELARTEINSSGGVLGGKNITLLVKDDEASLSKGRLVAQEIANNIDVAAVIGHLNSYITEPASQIYEQAGLLMITPGASGQKMFEDGGKLIFRSLPGNREQARQIGDYAVSQGYKRIAIYYIKNEYGIDLANFFEQRANELGINVVDRRSYNMNADNHAAIFKDWALFLKMDAIFLIGSLPESGQILREARAAGITVPIFGGHGMDSADLIKLGGKSAEGTVVFSLFNIVDPRPEVQSFVERYQKRFGVEPDSSAAAGYDTLKLVAHAIDVAHSEVPAKTAEAMRATKNWSGVTGMYTFNEKGDLVGKRLAKAEVNQGKFVYFEITPPRTVTTWPTAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYK8</accession>
    <name>A0A2S9GYK8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2476</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92746">
        <property type="protein sequence ID" value="PRC92746"/>
        <property type="gene ID" value="S2091_2476"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015777050" evidence="1">
        <location>
            <begin position="25"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="142" mass="15874" checksum="5FF8E61EC4EE91A9" modified="2018-07-18" version="1">MKNMILQKITGIFLSTLATASAIASPCDGINRSINLQNKRFFAETITKQLKAQIPDVASVQILQYFAYKDWSVVYVNTQVSDEVFLIYHDSPLKGKYLDSLAGAYAANEEQSVYDHLINGDSKGIPTKLAKCIAWHITKDRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZ24</accession>
    <name>A0A2S9GZ24_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative signal transduction protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2374</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92957">
        <property type="protein sequence ID" value="PRC92957"/>
        <property type="gene ID" value="S2091_2374"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013976">
        <property type="entry name" value="HDOD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08668">
        <property type="entry name" value="HDOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51833">
        <property type="entry name" value="HDOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HDOD" evidence="1">
        <location>
            <begin position="13"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="275" mass="30708" checksum="EA75F5B715C4D6F2" modified="2018-07-18" version="1">MNFDALFLQQHALPTIPKVVQEVIDSFNNDRVSVEDIAQKLAADQVLSAKILRLANSSYYHVSRSIGTVDDAVLMLGFMTVRTLVVSTGLTNGFKNVSGFDLKKFWRYSMHTAVIAKWLSKQKKTNSDFAFTVGMMHAIGQLVMHAAMPEEMMEVDKIAGALDARRFDIESKSFGYNFADVGAELAVRWKFPDEFGTAIRCFPHPLEHDNFDPMAGIIHLAAWRSRAFEHDLTAEEMQATFPTEVAAKLNIRIDMILTDMPGISELSEGLESLVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZ44</accession>
    <name>A0A2S9GZ44_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 4">Integration host factor subunit beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_2426</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Heterodimer of an alpha and a beta chain.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the bacterial histone-like protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC93009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93009">
        <property type="protein sequence ID" value="PRC93009"/>
        <property type="gene ID" value="S2091_2426"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000119">
        <property type="entry name" value="Hist_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010992">
        <property type="entry name" value="IHF-like_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005685">
        <property type="entry name" value="IHF_beta"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33175">
        <property type="entry name" value="PTHR33175"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00216">
        <property type="entry name" value="Bac_DNA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01727">
        <property type="entry name" value="DNABINDINGHU"/>
    </dbReference>
    <dbReference type="SMART" id="SM00411">
        <property type="entry name" value="BHL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47729">
        <property type="entry name" value="SSF47729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00988">
        <property type="entry name" value="hip"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="2 4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4" id="KW-0810">Translation regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00018700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC93009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="101" mass="11220" checksum="ED4B78EC6B8E2C42" modified="2018-07-18" version="1">MTKSELIACLAERYPQLVAKDADFAVKTILDAMSEALAVGQRIEIRGFGSFSLNSRPPRIGRNPKSGDKVMVPEKRAPHFKPGKELRERVDAMVGQPIRND</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZ66</accession>
    <name>A0A2S9GZ66_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_2115</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93029">
        <property type="protein sequence ID" value="PRC93029"/>
        <property type="gene ID" value="S2091_2115"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="7"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="5">
        <location>
            <begin position="132"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="132"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC93029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="229" mass="25850" checksum="40775402FF497AD7" modified="2018-07-18" version="1">MSLDKTTILIVEDEPAIVELVSFTLRAAGWETYAVNNTADAWAFITRRMPHLVLLDWMLPDQSGIRLLSKIRADRQFGALPIIMLTAKSMEEDKIAGLDHGADDYVTKPFSPRELTARIKTVLRRKAPEHGQGVLSAGPIVLDPVSCSVLLNDQRIEIGHAEFKLLKFFLAHPDRVFSRSQLLDKVWGDHVVIEERTVDVHVLRLRKVLKTSESLIKTVRSVGYMLSEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZ69</accession>
    <name>A0A2S9GZ69_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">S2091_2118</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93032">
        <property type="protein sequence ID" value="PRC93032"/>
        <property type="gene ID" value="S2091_2118"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="126"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="160"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="10">
        <location>
            <begin position="180"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="8">
        <location>
            <begin position="244"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="9">
        <location>
            <begin position="318"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="8">
        <location>
            <begin position="369"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="9">
        <location>
            <begin position="458"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="7">
        <location>
            <begin position="562"/>
            <end position="793"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC93032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="808" mass="90207" checksum="30FF6CB39AD5D13C" modified="2018-07-18" version="1">MRITLKWKVIVGCILLEIIALAFIAGINFEINNDYLDQISQNRLQQLNTCLNSQFEHRRFDLKDDVVASLMDACQTKDSLTYFVLFDQNDRVVLKKGWPGSELSGTTSLSSAISAIGSLPWKTPSFYNSMLLTTPQYSHLLYGGTTVFKQQAQFELAKKALVLSLIAIVLSIAFFVLLMGWLSRHLKMLENAANEILVGNYDVSIDYLGNDEIGRVGFAINLVTTTLKNEIQALRKSEESERQTAARMLKVIDAVPDFMLLSRISDAYIIYANAGVENMTGHAYSELVGKTIDEVELGITKAQRKDWQNQLNRNGSLTNYETIIKHKDGSLINVLVSASLLEIDNAAHVLIICRDITDRKLVEAAVAHANRQLNYVLDAASEIAIISTDVNGIVQMFNRGAEKMLGYRAREQIGMPMRFDIHDTYELVQRSKELSRQFGREVQTSEVLTLIPVKLGSETRNWTYICKNGQRLNVSLTVTRVQDGAGKVVGFLGIARDITLQLQAEQALQELNYQLEKRVEERTAELGETNKNLANTMHNLQLAQAELVRSEKLTALGDIVAVVAHEINTPIGNCLTVATTLRDRSVELYEEVEQGTIRRSSLSRYMNDSKTGMDILIRGLNRSSELVSNFKQVAVDQTSEQRRVFKLHKVVNEVVALMIPMLRKTPYKLSISIPEDISMDSFPGPIEQIVTNLINNSILHAFEEDKQGNMTLTAAKQDQNVKIEFSDDGKGIPEHHLNRIFDPFFTTKLGRGGTGLGLNIVHNIVRKMLGGQIEVSSQASGGTSFVIVLPLFAPAASPPEKRQSTHFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZG2</accession>
    <name>A0A2S9GZG2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Phage tail tape measure protein, lambda family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_2179</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93093">
        <property type="protein sequence ID" value="PRC93093"/>
        <property type="gene ID" value="S2091_2179"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006431">
        <property type="entry name" value="Phage_tape_meas_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09718">
        <property type="entry name" value="Tape_meas_lam_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01541">
        <property type="entry name" value="tape_meas_lam_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="112"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="domain" description="Tape_meas_lam_C" evidence="4">
        <location>
            <begin position="662"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="862"/>
            <end position="882"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="496"/>
            <end position="541"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF09718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC93093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="882" mass="94154" checksum="1673FFB920AAEB11" modified="2018-07-18" version="1">MGETKMSEVIGSGVIQVSADSSKLKAGIDDAKKSIASLGDANEKSSARSSRSIDNYVKRLQTQNATLGKSTREVELYKLQLKGATAQQLKAADSALKMAKSQRKSAQNMQSLKTGFIAVAAAATAAAYAVYALTGRMIEQITVYQGISEKIGDTAVSVSSLKLASDLSGVALDRVAAASVKLTSALSKTDDESKLTGAAIKALGLDFQTFKSLSPVEQIDAIAKAMAGFKNGAEKTAVAVALFGQTGAEMMPFLNDLADKGQRHTELTEQQIASTDNFNKSIIILKNNFSNLSQKLVANAIPVLSSLHSVFVDLSEDETVMAVASDHLNGALEIGIVLFQTLAVVGSEVGYVFLSVGREIGAIAAQLVALAHGDISGFKAISNAVKEDAERARKELDKFQQKIMSIGVMPEKNEKTSKPVKESPKLDTSGLVIKTNTGESGQLAKAQLDADLRNIRQSTDALISTYANAEKIMQARRAAGLVADRDYYLSKLSFINLNKEAQEKSLQAEIARLQTEKFIGKEKIENDKKIADAQAKLLKSREDAVTNIQINSIAEAAAIDKTRRAYDDATFSANNYLAAIDRQNQRDISKIGRGVDFGLQADITNKIDDKKIEATQRLDRDKTKGLITAEEYQQHLAIVEDTYAKEIALAQNKNIAIKELEGDWINGAKSALENYADQSSNVASLTENLFTKGMDGMTDSIVDFAMTGKSTFGDFAKSMIADIAKMMIKMLAMKAIKATMGMFADGGAFDGGKQAFAKGGAFDSGVTKFASGGAFTNSIVDQPTNFNMGQMGEAGPEAIMPLTRMSGGELGVRAQGVGNSVSSSIQVNVYVQQDGNSQVDAPSGMQQFGKELADFVDARIGKSTRDAQRPGGSLYNLKHGTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZG4</accession>
    <name>A0A2S9GZG4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Arabinose efflux permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_2211</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93125">
        <property type="protein sequence ID" value="PRC93125"/>
        <property type="gene ID" value="S2091_2211"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="64"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="88"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="112"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="144"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="174"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="220"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="253"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="285"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="309"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="347"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="373"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="22"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC93125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="407" mass="41923" checksum="4CF87F4B156B56DC" modified="2018-07-18" version="1">MNHSPPHLNQPPGQSDWRIWLSIVFLGIGAFTIVTTELAPIGLLSAIAQDIGRSESAIGLTVTLYAWIGAFSALLAAIALGRIPRKPLLIGLMLCLALSNGAAMTADGFGLLLAARACGAVAHGLFWAVIAASAAQIAPPRHVGLAMSIVFGGVSAASVLGVPLATLIGQESNWRIAFGAVGALSLLTALGMLAVLPRLEQNQVKDTRAALGSVLRRMDLCSIYVATAFAVTAHFAAFTFIEPFLREAPGMQATMVIALLFGFGTSGLAANFLTGIFIDRYLRALLLLALALMTLSLFALGIWGTQISVAGVGAMLILWGASISTIFVGFQTWILRTAGAAAMPASAVYVAIFNAAIGSGAMIGAWVQSHSGFAAVMMVGGLGGAASILVVTALGSHTSIPQSELQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZN4</accession>
    <name>A0A2S9GZN4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2162</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93076">
        <property type="protein sequence ID" value="PRC93076"/>
        <property type="gene ID" value="S2091_2162"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="48"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="103"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="49"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="132" mass="15357" checksum="8435C8981010F9E1" modified="2018-07-18" version="1">MNRVARVIPVNYIEESPLDLCLRLWAKSKQVDDKDLGIQKRFSLKSDYDGYGSNDTYQSDSSQSRRDNEIADATEAMIMSLTGCHRWAIQRSMNVCRVWNYPQLNYLNELEAARAELEKKLRNNLATRTEFC</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZP9</accession>
    <name>A0A2S9GZP9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="10">TonB-dependent Receptor Plug Domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">S2091_1950</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93212">
        <property type="protein sequence ID" value="PRC93212"/>
        <property type="gene ID" value="S2091_1950"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039423">
        <property type="entry name" value="TonB-dep_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32552">
        <property type="entry name" value="PTHR32552"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="3 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0675">Receptor</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="2 5" id="KW-0798">TonB box</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015448367" evidence="7">
        <location>
            <begin position="26"/>
            <end position="847"/>
        </location>
    </feature>
    <feature type="domain" description="Plug" evidence="9">
        <location>
            <begin position="94"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="8">
        <location>
            <begin position="377"/>
            <end position="845"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="36"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC93212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="847" mass="89997" checksum="6C83832911D0EDB3" modified="2018-07-18" version="1">MKLRTKRLSIVIAVASAFMATAATAQEVAATAPLANPAPTTDAQPAVPVAEAASVDQTPAPEVKQSAAAASAAAKSGGIQTVVVTAQKRKEDASKVPLSISVLGGDELTSQHIGDYADITRAIPNISFSGGGGGGDAGDGPGLSNIEIRGISSSAGAATVGIYMDDVSMTVANLYSMGSAEPKFFDLDHVEILRGPQGTLYGSSSMGGTIKFITNQPNLKEQTTDVYTEFSSFKGGKDSYTGNVVFNQPLTPGELALRVGIQGGHQGGYIDQVNANGNVIDSGINWQDDSVLHLAMKWAPTKNLTITPSVFYQKVKTGDTDVSYTQVLESGQQNGIILPPYQTSKIMHEPGSDELLVPSLTISYGTDLGDLTAVTSYFKRTFSRIQDGSETNSVQLGTSGSYIDNVNYPAFGAAVAALPSAVTLNNQVAQFSQEIRFASKQYEPGGSPITWLVGAYAANEHTSIIENDYVYGLNKTFSNFGLSPTDPTVFVPGTYLPGFPSDNTFAGGYKFHDTQQSIFGEMSYYFVPTVHATVGLRYLHAQEVFSSFQSLFYNGGNTTNDSTQSGNKSTPKLSVIWEVSPTSSVFASAAEGFRVGGNNDAVPATLCGLPGPNPLSFNSDSLWSYEVGNKSRFLDNKVTFNSSLFYVKWKNMQQEIELPCSFDYNVNVGSATSYGAEVELKVKPISSLLIDLAGGYTHATLDNSDGAETGVAGAVAGANIPGVPRYNIALTTTYNYDITDNYFGFLRGAARWTGASNGGFSELPNSNGTITPPNLFAGVPNPDFNRPAYHTIDASTGVSWGAWEATLFVKNMFNNNMIIQRPIVQATLGEVYRMEPRTIGMSLSAKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZS7</accession>
    <name>A0A2S9GZS7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Addiction module toxin, RelE/StbE family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1969</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93231">
        <property type="protein sequence ID" value="PRC93231"/>
        <property type="gene ID" value="S2091_1969"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2310.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007712">
        <property type="entry name" value="RelE/ParE_toxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035093">
        <property type="entry name" value="RelE/ParE_toxin_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05016">
        <property type="entry name" value="ParE_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02385">
        <property type="entry name" value="RelE_StbE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-1277">Toxin-antitoxin system</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="95" mass="10772" checksum="61F8434D143E14EA" modified="2018-07-18" version="1">MILKWNRKAQEDRRNFLVSIGQSSLSAALKHDEVIEAKAELLLNPLTSYKAGRVLGTHEFIISKRYVLVYRIKGDVVEILRVLHTAQAMPTNLLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZT5</accession>
    <name>A0A2S9GZT5_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF190 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1987</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0166 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93249">
        <property type="protein sequence ID" value="PRC93249"/>
        <property type="gene ID" value="S2091_1987"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003793">
        <property type="entry name" value="DUF190"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011322">
        <property type="entry name" value="N-reg_PII-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015867">
        <property type="entry name" value="N-reg_PII/ATP_PRibTrfase_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02641">
        <property type="entry name" value="DUF190"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54913">
        <property type="entry name" value="SSF54913"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF190" evidence="2">
        <location>
            <begin position="6"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="104" mass="12058" checksum="240632AFA7AF4116" modified="2018-07-18" version="1">MNGYQLEFFTLQDSFHNGEKISDWLLDVARSHNIRGATVFKGTCGFGHDHHNYSSIPLYGNVDHPEQITLIVNDDECERLFDILRKENLHLFYVKMPVEFGQVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H021</accession>
    <name>A0A2S9H021_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">S2091_2055</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93317">
        <property type="protein sequence ID" value="PRC93317"/>
        <property type="gene ID" value="S2091_2055"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017232">
        <property type="entry name" value="NtrY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13188">
        <property type="entry name" value="PAS_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037532">
        <property type="entry name" value="STHK_NtrY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="38"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="75"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="304"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="10">
        <location>
            <begin position="329"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="9">
        <location>
            <begin position="393"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="8">
        <location>
            <begin position="546"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="209"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC93317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="776" mass="84788" checksum="4A1A26671EB210DB" modified="2018-07-18" version="1">MTRLLRYLFVVGAAVTGIFLFLIASLSDQTAVFEKNYIWLFGLNSLVAIALLALIVLLLTRLYRRYKKKEFGTRLLTRLVILFATLAIVPGALIYAVSIQFVSRSIESGFDARVENAIDAGLNLGRSALDNSLSELTIRAHRSAQELADLSGSNRVIQLSRLFEQNQQLEATIVTGRGQLVSSTGGQFSSLLPDMPTQAMLRQARNNREFSDYEGGNETSPDGSMDGDGGNELTPKATQQTGIRLRVLVLIPNNQDSLSLHEDPQYLQLIQPIPESIRINTDKLASARSKYQELAAGRTILRKIYIATLTLTLLLAIFASIVSAFLLATDLIKPILLLAEGTKAVTQGNLSPRPIIASSDELGSLTKSFNIMTHQLFDARATVEKNRSELQNAKAYLESVLANMSAGVMVLDRSFHLVTCNESVERILQLPLENYIGQPLIEIPGLSTFAHAIAKAFSEHNAQSAAGDNADQHWQQQIELPRHLTGEQDSGFDFGEMANNNQTITLLARGSHLPVSSGTGNVVVFDDITNIISAQRSIAWGEVGRRLAHEIKNPLTPIQLSAERLQMKLHDKLNVADAAILSKSTATIVNQVSSMKRMVDDFRDYARTPPAHLTPLNLNGLIDEVMNLYIGGDGADVIRMKLSTDLPTIMGDATQLRQVIHNLLQNAQDSVNEQHGNSPDRQIDVITEVVHYNNSEGEIQSAASLSIIDNGVGFSSKILARAFEPYATSKPRGTGLGLAVVKKILEEHGGRVDIKNRTDGNGAKVAILLLKLAPNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H077</accession>
    <name>A0A2S9H077_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_2096</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93358">
        <property type="protein sequence ID" value="PRC93358"/>
        <property type="gene ID" value="S2091_2096"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013655">
        <property type="entry name" value="PAS_fold_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08447">
        <property type="entry name" value="PAS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PAS" evidence="6">
        <location>
            <begin position="27"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="7">
        <location>
            <begin position="103"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="5">
        <location>
            <begin position="230"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="153"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC93358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="445" mass="49703" checksum="1060CDE72E9B5E03" modified="2018-07-18" version="1">MSFEFEEFDELVAPAVKSLVVPKKETGYSRLQYLIDNTTAIIYASVPTGDFRMTYVSGNAFHVLGYRPEQMIEDPNFWFNHIHPDDTAQIFSSLALLFSEGQRTYEYRFLSSAGNYIWMNDMLRLVCDEDGKPVEVVGSLTDITERKNMEVDLQRKGEEQQALIKKLQEAHQQLLQAEKMASVGQLAAGIAHEINNPIGFVNSNMNSMQTYVTTLFGVIEQYNTAIGSLTLSSETKDAIAAINKNADLEFVKEDMADLVRESLDGLRRVKDIVQSLKDFAHVGETEWQEADIHQGLDSTLNIVKNEIRYKATIEKRYGVLPLVPCIISQLNQVFMNLFINAAHAIKDKGVIAISTGTEIIEGANWIWIKVTDTGCGIDPENLNRIFEPFFTTKPIGSGTGLGLSLAYGIINKHNGNITVKSVVGKGTRFTIYLPVDQKEQIKAVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H094</accession>
    <name>A0A2S9H094_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 13">Phosphoenolpyruvate-protein phosphotransferase</fullName>
            <ecNumber evidence="5 13">2.7.3.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12 13">Phosphotransferase system, enzyme I</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">S2091_2024</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>L-histidyl-[protein] + phosphoenolpyruvate = N(pros)-phospho-L-histidyl-[protein] + pyruvate</text>
            <dbReference type="Rhea" id="RHEA:23880"/>
            <dbReference type="Rhea" id="RHEA-COMP:9745"/>
            <dbReference type="Rhea" id="RHEA-COMP:9746"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:29979"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:64837"/>
            <dbReference type="EC" id="2.7.3.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 13 16">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 13">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 13">Belongs to the PEP-utilizing enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.3.9" evidence="5 13"/>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93286">
        <property type="protein sequence ID" value="PRC93286"/>
        <property type="gene ID" value="S2091_2024"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008965">
        <property type="term" value="F:phosphoenolpyruvate-protein phosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009401">
        <property type="term" value="P:phosphoenolpyruvate-dependent sugar phosphotransferase system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.274.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008279">
        <property type="entry name" value="PEP-util_enz_mobile_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018274">
        <property type="entry name" value="PEP_util_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000121">
        <property type="entry name" value="PEP_util_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023151">
        <property type="entry name" value="PEP_util_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036637">
        <property type="entry name" value="Phosphohistidine_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024692">
        <property type="entry name" value="PTS_EI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006318">
        <property type="entry name" value="PTS_EI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008731">
        <property type="entry name" value="PTS_EIN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036618">
        <property type="entry name" value="PtsI_HPr-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_Kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05524">
        <property type="entry name" value="PEP-utilisers_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00391">
        <property type="entry name" value="PEP-utilizers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02896">
        <property type="entry name" value="PEP-utilizers_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000732">
        <property type="entry name" value="PTS_enzyme_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47831">
        <property type="entry name" value="SSF47831"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="SSF51621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52009">
        <property type="entry name" value="SSF52009"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01417">
        <property type="entry name" value="PTS_I_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00742">
        <property type="entry name" value="PEP_ENZYMES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00370">
        <property type="entry name" value="PEP_ENZYMES_PHOS_SITE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 13" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="13" id="KW-0418">Kinase</keyword>
    <keyword evidence="13 16" id="KW-0460">Magnesium</keyword>
    <keyword evidence="11 13 16" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 13" id="KW-0598">Phosphotransferase system</keyword>
    <keyword evidence="20" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 13" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="13 20" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 13" id="KW-0813">Transport</keyword>
    <feature type="domain" description="PEP-utilisers_N" evidence="19">
        <location>
            <begin position="7"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="domain" description="PEP-utilizers" evidence="17">
        <location>
            <begin position="162"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="domain" description="PEP-utilizers_C" evidence="18">
        <location>
            <begin position="260"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="region of interest" description="PEP binding" evidence="15">
        <location>
            <begin position="463"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="active site" description="Tele-phosphohistidine intermediate" evidence="14">
        <location>
            <position position="198"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="14">
        <location>
            <position position="511"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="305"/>
        </location>
        <ligand>
            <name>phosphoenolpyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="342"/>
        </location>
        <ligand>
            <name>phosphoenolpyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="440"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="464"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="474"/>
        </location>
        <ligand>
            <name>phosphoenolpyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00016544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00033235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRNR" id="PIRNR000732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR000732-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR000732-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR000732-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF00391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF02896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF05524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="PRC93286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="580" mass="63403" checksum="EF28D8AB92A57895" modified="2018-07-18" version="1">MASFTLQGIPVSRGIAIGRAHLLRPAALEVQHYLVGQEQVEAEVLRLQNALAEAERELQKIWSDLPADAPSELGAFLDVHSLFLSDPMLAQAPLEIIRTRHYNAEWALVTQIDVLLAQFDEIEDDYLRERKADIEQVADRLLKLLTGSATTLPPNAGVDELNTHMIVVARDISPADMMQFQDSAFVGFVTDEGGRSSHTAIVSRSLGIPAVVGMGNASHLIQQDDWLIIDSVAGVVIVAPQQIILDEYREKQAAIQRFRKKLAKLKKTSAVTKDGTPITLLANIELPEHAAAANEVGASGVGLFRSEFLFMGRDGILPSEEEQFEAYRATVQAMKGRPVTIRTLDVGADKPLDEADVATLNPALGLRAIRYCLAEPQLFLTQLRAILRASAFGKVNILIPMLSHLFEIDQTLAMVAQAKQQLILQGIAFDADIKVGAMIEVPAAALSLPMFVKKMDFLSIGTNDLIQYTLAIDRADYAVAHLYDDVHPAILQLLAMTVAAADKAGIPVAICGGMAGDIKLTRLLLGMGFRELSMPPAQLLEIKQEVMNIDLLLFNPIIKKILRSYEPEVIAEGIRALQLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0F5</accession>
    <name>A0A2S9H0F5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Fimbrial assembly protein (PilN)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1849</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93462">
        <property type="protein sequence ID" value="PRC93462"/>
        <property type="gene ID" value="S2091_1849"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007813">
        <property type="entry name" value="PilN"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05137">
        <property type="entry name" value="PilN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="112" mass="12719" checksum="A11D38D6DD4A4C0A" modified="2018-07-18" version="1">MQKIAPGAPNPRDSAIERRSVEISSLLHRRWTDSLLAVERVTNKNITILEFHPDFGNEKLVLRGEAREFDALADYIKQLNATGLVKNVALMHEQAISREHVDTIEFELKGDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0P6</accession>
    <name>A0A2S9H0P6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1823</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93436">
        <property type="protein sequence ID" value="PRC93436"/>
        <property type="gene ID" value="S2091_1823"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="22"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="105" mass="12371" checksum="3B6558329760972C" modified="2018-07-18" version="1">MSTSELKFEFFKKMKIARYYDCLWRPCFVPITFIFTLLYKYLFWNMPSIQLVVLFMIIYFVVGVILSIKLNATVECPNCGYAVFSKKTLLRPKQCVNCGFSFSRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0Q3</accession>
    <name>A0A2S9H0Q3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">FemAB-related protein, PEP-CTERM system-associated</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1920</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93533">
        <property type="protein sequence ID" value="PRC93533"/>
        <property type="gene ID" value="S2091_1920"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038740">
        <property type="entry name" value="BioF2-like_GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017469">
        <property type="entry name" value="PEP-CTERM_FemAB-rel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13480">
        <property type="entry name" value="Acetyltransf_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03019">
        <property type="entry name" value="pepcterm_femAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acetyltransf_6" evidence="1">
        <location>
            <begin position="189"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="367" mass="41901" checksum="1A1B1F05C6058C08" modified="2018-07-18" version="1">MNTVTENALQSFSAPDSDLDRAANSAPLIIKLMQANDTQRWDEFVQRCPDATFFHRAGWQSVIERAFGHRTWFYYAESGDEIIGVLPLAEIKSALFGHSLCSLPFCVYGGVASESSAAKLALTQKAQELAALLKVGYLEYRNIQPQNPSWHGKDLYVTFRKEIDPDEEKNMLAIPRKQRAMVRKGIKAELHSELDQGIERFFHAYASSVHRLGTPVLSKQFFRLLKEVFAEDCEVLTITKDSRVIASVMSFYFRDEVLPYYGGGTAEAREVAGNDFMYWELMRRACARGYKIFDFGRSKRGTGSFDFKKNWGFEPQPLYYEYQLHASNAVPDNNPLNPKYQLFIKMWQRLPLSVANFIGPHIVKNLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0Q9</accession>
    <name>A0A2S9H0Q9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative pyridoxal phosphate-dependent enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_1549</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the DegT/DnrJ/EryC1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93548">
        <property type="protein sequence ID" value="PRC93548"/>
        <property type="gene ID" value="S2091_1549"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00616">
        <property type="entry name" value="AHBA_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000653">
        <property type="entry name" value="DegT/StrS_aminotransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30244">
        <property type="entry name" value="PTHR30244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01041">
        <property type="entry name" value="DegT_DnrJ_EryC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000390">
        <property type="entry name" value="PLP_StrS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="186"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="2">
        <location>
            <position position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR000390-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000390-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC93548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="370" mass="41140" checksum="865FF676A3D9BFCC" modified="2018-07-18" version="1">MSTNPNIYVTQPLLPPLNEFIPYLEKIWTNKILTNGGPFHQQLEKELCEHLGVEYISLFTNGTIALVTALQSLRITGEVITTPYSFVATAHSLLWNGIKPVFVDVDPETLNLDPAKIEAAITPQTTAIMPVHCYGHPCDVKAIQKIADTYNLKVIYDAAHAFGVKDENGSILRHGDLAVLSFHATKVFNTFEGGAIVCPDLKTKQRIDQLKNFGIVDEVTVVAPGINGKMSEINAAFGLLQLKHLDQSLVRRKEIDTIYRERLAAVSGIQCLSDSGEVVANYSYFPVLVSHSYPLSRDALFQKMKDHGIFTRRYFYPLITDFPMYRSLPSAQHSNLPNASDAASRVLCLPIYPALTNEEINRVIEVILAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0U4</accession>
    <name>A0A2S9H0U4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">4Fe-4S dicluster domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_1603</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93602">
        <property type="protein sequence ID" value="PRC93602"/>
        <property type="gene ID" value="S2091_1603"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00037">
        <property type="entry name" value="Fer4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="14"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="66"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC93602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="96" mass="10425" checksum="7BE4525F4D64F6DF" modified="2018-07-18" version="1">MTTTANCKQSPGIIVPVVNFKRCEGKADCAVVCPENVFEIQRIKPADYQKLNLLNQFKLRVHGMQVAYAPNADACKACGLCVTACPEKAITLARLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0W4</accession>
    <name>A0A2S9H0W4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1620</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93619">
        <property type="protein sequence ID" value="PRC93619"/>
        <property type="gene ID" value="S2091_1620"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="101" mass="11183" checksum="3352A07195F829B4" modified="2018-07-18" version="1">MINQSANASSRPEILIAAVLHLMSHYSTNNALNKDHGVCVKLAAVIERHLTILSELPDLAPVLRATCEQLSEQWTMVVEHTMPQQSKSGLLARWRNGAQLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0X9</accession>
    <name>A0A2S9H0X9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cation/multidrug efflux pump</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1903</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93516">
        <property type="protein sequence ID" value="PRC93516"/>
        <property type="gene ID" value="S2091_1903"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2090.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027463">
        <property type="entry name" value="AcrB_DN_DC_subdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001036">
        <property type="entry name" value="Acrflvin-R"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32063">
        <property type="entry name" value="PTHR32063"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00873">
        <property type="entry name" value="ACR_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00702">
        <property type="entry name" value="ACRIFLAVINRP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82714">
        <property type="entry name" value="SSF82714"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="338"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="371"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="401"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="435"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="481"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="538"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="870"/>
            <end position="889"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="896"/>
            <end position="916"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="922"/>
            <end position="943"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="971"/>
            <end position="990"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="996"/>
            <end position="1019"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="1036" mass="114286" checksum="19C46900073969ED" modified="2018-07-18" version="1">MKSRLNLSRWALENIPMTRYLIAALLIGGILSYSRLGQDEDPPFTFRVMVISANWPGATALQMAEQVTDKLEKKLQETPYIDKIRSYSKPGETLITLQLRESTPPAETIAAWYQVRKKIGDISGTFPKGVIGPFFNDEFGDTFGSIFALSGDGYTYAEMKDYADFVRQQFLQIPSVSKVELYGVQDEKLYIEFSQKKFARLGISFDAIVNQLNAQNVIESTGVLVTPYDNLQLRVSGALKSGKDLENLPLRANGITFRLGDFATIKRDYIDPPHDKMRYNGREVIGLGISMEHGADIIELGKNLQNAAEVIKAKLPYGLELQRIVDQPNAVKSSVSEFLRSLSEAVAIVLAVSFLALGLHVKPWRLDVRPGLVVGLTIPLVLAVTFLFMRIFDIDLHKISLGALIIALGLLVDDAIIAVEMMVRKMEEGMSRFDAATFAYTSTAMPMLTGTLITAAGFLPIGLAKSMAGEYTFSMFSVNTLALIISWLVAVLFTPYIGYILLKVKPAVSADSHQTLFDTPFYSRIRRMVNWCVEWRKATILLTLAAFALGLFGFGFIEQQFFPDSSRPELMVELWLPEGASFTSTEVQAKKMEQFVLHQNGVESVTSYVGTGSPRFYLPLDQIFPQSNVAQLVILPKSLAFREALRLKIVAAFKNDFPEVRGRVKFLPNGPPAPYPVQFLISGDSLIKVRSIADQVKEIMRANPNTVGVNDNWNESIKVLRLNLDQDKLLALGIGSQTVMRTANTILSGTTIGQYRENNKLIDIVIRQPVEERATITALNDANIQMPTGETIPLSQLAQVRFVWEPGVVWREGREWAITVQSDVADGIQGPTVSDQIEAKLTNLRAALPAGYKIDLEGSAADSSKAQDSIIANVPLVIFIIFTLLMLQLKSFSRALLVFLTGPLGVAGAAIALLLLQRPFGFVAQLGVIALFGMIIRNSVILIDQIEQNIAAGATPWNAIVESAVRRFRPIILTAAATVLAMIPLSRSVFWGPMAVAIMGGLIVATVLTMFFLPALYAACFRVKSDANKNDAERIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H143</accession>
    <name>A0A2S9H143_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cytochrome c oxidase assembly protein CtaG</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">S2091_1700</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Single-pass type II membrane protein</topology>
            <orientation evidence="2">Periplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the COX11/CtaG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93699">
        <property type="protein sequence ID" value="PRC93699"/>
        <property type="gene ID" value="S2091_1700"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.370.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023471">
        <property type="entry name" value="CtaG/Cox11_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007533">
        <property type="entry name" value="Cyt_c_oxidase_assmbl_CtaG"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04442">
        <property type="entry name" value="CtaG_Cox11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005413">
        <property type="entry name" value="COX11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110111">
        <property type="entry name" value="SSF110111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0186">Copper</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="21"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009620"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00015384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC93699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="188" mass="20852" checksum="67671C5D5EE72978" modified="2018-07-18" version="1">MKNSKAGKLLAKINSVMLGKLVVVAVLMFGFGFALIPVYKQICELTGVNILTTKDDKVTVPVNSQIDKSRVVTVEFDANTTGPWRFRPVVSSMKIHPGEMTQVVYEVVNSQPRKMDAQAIPSYAPQEATPFFKKVECFCFKQQTLGPNEARQMPVVFFIDPKLPKNVTTITLSYTFFEVGGNTVKAPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1J6</accession>
    <name>A0A2S9H1J6_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Histidine kinase</fullName>
            <ecNumber evidence="4">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">S2091_1447</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="4"/>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93838">
        <property type="protein sequence ID" value="PRC93838"/>
        <property type="gene ID" value="S2091_1447"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033479">
        <property type="entry name" value="dCache_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013655">
        <property type="entry name" value="PAS_fold_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029151">
        <property type="entry name" value="Sensor-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02743">
        <property type="entry name" value="dCache_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08447">
        <property type="entry name" value="PAS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103190">
        <property type="entry name" value="SSF103190"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="319"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="13">
        <location>
            <begin position="433"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="12">
        <location>
            <begin position="486"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="11">
        <location>
            <begin position="612"/>
            <end position="830"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="PRC93838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="830" mass="93495" checksum="73D1E43009C8EE69" modified="2018-07-18" version="1">MKFTATKVRISIIVCSLLLCIAWGSGAWFYELDQFKLRTNSLIDKENEHAGTRGETISADIRRSLKVMYGLPEVLASWQEVVNVLKPQQRASDAIKQRLAKGRVDTTLSALEQINHLLLLAKSDFSADVIWIMDANGNCVAASNFDLPTSFIGTNYKEREYFTSAMGGNNGYQFAVGKVSHQPGLYFSAPVYLKQKVIGVVVVKVDITRLAHNIDISNTFLVDENGVVILSDAKHLEMKVVPGNTIDKMSIARRLSVYQREQFELVQIHAWPDSRYARLTMIENSPEAYVLNITSINGGELKIYVLSPAKEIVVLDQEYFRLFLLVTLCGSALIIIAAGIIWYVHGNLVTSQILQMQHDELHEAQRLAQMGSWSYEYASRQLHCSDELIHNFFMLEKLTVKPTLDHILVNILPEDQERVKKVFNEGLKTGNGYTVEYRIMRKNGEIRNVIGKTIIEKNEKGQRIKVTGTCRDVTEEQRVLRAIEASENHLRRVLNSSLIGIIQGNDTGVICEMNKAFMALTGYTKAHLFENKLRWKDIAAVEYQQLDAANIFGQIDTPIPFEMELKCSDGKLLQVLIGLAKIEELRSEWVCFVLDLSERNRMSRLKSEFISIVSHELRTPLTSIRGSLALLEGGITGELEEKSMELVKIAHRNSRRLIDIVNDILDMEKLDAGKMVFEMRSIEITSAIRQAIEVNQAFAANLNVRYVMHSFPEPAYIWGDANRLMQILTNLLSNAAKFSPSGAEVELRLCKAEHHWRIEVHDTGPGIPEEFRGRIFGAFAQAEDANTRQKGGTGLGLNITKIMVEKMDGKIGFDSEEGQGATFWVSFTAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1S2</accession>
    <name>A0A2S9H1S2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Sigma70-ECF: RNA polymerase sigma factor, sigma-70 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_1531</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93922">
        <property type="protein sequence ID" value="PRC93922"/>
        <property type="gene ID" value="S2091_1531"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000943">
        <property type="entry name" value="RNA_pol_sigma70"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007630">
        <property type="entry name" value="RNA_pol_sigma70_r4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04545">
        <property type="entry name" value="Sigma70_r4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00046">
        <property type="entry name" value="SIGMA70FCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="5">
        <location>
            <begin position="26"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4" evidence="6">
        <location>
            <begin position="180"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC93922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="239" mass="28055" checksum="D425ECCE879B1B42" modified="2018-07-18" version="1">MHTSEVAALWHDWHENKGREVRDRIIEHYLPFTRMMAAKLYSKRHSEEFEFDDYLQFATIGLMESIDRYESNSLAQFTTYAAKRINGAVLDGVEQLSERQQQISTHQRRLKERSKLAGDALKTGTGTLFDQLAEIAVGLALGHLLDDTRLYFDDETIEPYNQYRGVELRQLQNRLQILVEQLPERERLLIKYTYFNHMTFDAVAQQWGLTRSRIAQLHRSALDRLRKSALDLKQYDITC</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H244</accession>
    <name>A0A2S9H244_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">tRNA modification GTPase MnmE</fullName>
            <ecNumber evidence="7">3.6.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">mnmE</name>
        <name evidence="7" type="synonym">trmE</name>
        <name evidence="10" type="ORF">S2091_1203</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
        <text evidence="7">Binds 1 potassium ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer. Heterotetramer of two MnmE and two MnmG subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7 8">Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.-.-" evidence="7"/>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94030">
        <property type="protein sequence ID" value="PRC94030"/>
        <property type="gene ID" value="S2091_1203"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04164">
        <property type="entry name" value="trmE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.430">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00379">
        <property type="entry name" value="GTPase_MnmE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031168">
        <property type="entry name" value="G_TrmE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018948">
        <property type="entry name" value="GTP-bd_TrmE_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004520">
        <property type="entry name" value="GTPase_MnmE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027368">
        <property type="entry name" value="MnmE_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025867">
        <property type="entry name" value="MnmE_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027266">
        <property type="entry name" value="TrmE/GcvT_dom1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12631">
        <property type="entry name" value="MnmE_helical"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10396">
        <property type="entry name" value="TrmE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00450">
        <property type="entry name" value="mnmE_trmE_thdF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51709">
        <property type="entry name" value="G_TRME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 7 8" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 7 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 7" id="KW-0630">Potassium</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7 8" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="TrmE-type G" evidence="9">
        <location>
            <begin position="221"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="24"/>
        </location>
        <ligand>
            <name>(6S)-5-formyl-5,6,7,8-tetrahydrofolate</name>
            <dbReference type="ChEBI" id="CHEBI:57457"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="82"/>
        </location>
        <ligand>
            <name>(6S)-5-formyl-5,6,7,8-tetrahydrofolate</name>
            <dbReference type="ChEBI" id="CHEBI:57457"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="125"/>
        </location>
        <ligand>
            <name>(6S)-5-formyl-5,6,7,8-tetrahydrofolate</name>
            <dbReference type="ChEBI" id="CHEBI:57457"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="231"/>
            <end position="236"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="231"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="235"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="250"/>
            <end position="256"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="250"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="252"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="255"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="256"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="275"/>
            <end position="278"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="461"/>
        </location>
        <ligand>
            <name>(6S)-5-formyl-5,6,7,8-tetrahydrofolate</name>
            <dbReference type="ChEBI" id="CHEBI:57457"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC94030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="461" mass="50016" checksum="7CA24732588EF022" modified="2018-07-18" version="1">MNLDSSPIAAIATAPGRGGIGVVRVSGQEIMPLLKALFPEVNLKPRHATYLPFLDADGSVIDQGLALYFKAPHSYTGQDVLELQGHGGPVVLQMLLARCLEAGKDIGLRLAEPGEFTQRAFLNDKLDLAQAEAVADLIEASTEAAVKSASQSLSGAFSKVIHQLVEQVVQLRMLVEATLDFPEEEIDFLEKSDARGQLTRIQLALRKVVEQAAQGAILRDGLNVVLAGQPNVGKSSLLNALAGDDIAIVTPIAGTTRDKVVETIHIEGVPLNMIDTAGIREAMGEDAIDVVERIGIQRTWAEVAKADVILHLMDASRGPTREDELIADRFPPEVPIIRVWNKIDISGHHPAIDVMEGSAHVYVSAHEHQGIDLLRNELLRIAGWQQTGESLYMARERHLHALQLASEHLEHAAYHAAQTDQALDLFAEELRLTQDSLNSITGAFSSDDLLGVIFSRFCIGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2G0</accession>
    <name>A0A2S9H2G0_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">30S ribosomal protein S17</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rpsQ</name>
        <name evidence="6" type="ORF">S2091_1306</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Part of the 30S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3 4">Belongs to the universal ribosomal protein uS17 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94133">
        <property type="protein sequence ID" value="PRC94133"/>
        <property type="gene ID" value="S2091_1306"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01345_B">
        <property type="entry name" value="Ribosomal_S17_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019984">
        <property type="entry name" value="Ribosomal_S17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000266">
        <property type="entry name" value="Ribosomal_S17/S11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019979">
        <property type="entry name" value="Ribosomal_S17_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10744">
        <property type="entry name" value="PTHR10744"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00366">
        <property type="entry name" value="Ribosomal_S17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00973">
        <property type="entry name" value="RIBOSOMALS17"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03635">
        <property type="entry name" value="uS17_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00056">
        <property type="entry name" value="RIBOSOMAL_S17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 4 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 3 5" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC94133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="90" mass="10046" checksum="27B05FF91BCE70F8" modified="2018-07-18" version="1">MNDQVKQASKRTLIGTVVSDKMEKTVTVLIERHVKHPLYGKIIVRSTKYHAHNEGNVAKAGDVVEIQEGRPISKTKAWSVTRVVQVAQIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2H0</accession>
    <name>A0A2S9H2H0_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">30S ribosomal protein S10</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rpsJ</name>
        <name evidence="6" type="ORF">S2091_1316</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Involved in the binding of tRNA to the ribosomes.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the 30S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uS10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94143">
        <property type="protein sequence ID" value="PRC94143"/>
        <property type="gene ID" value="S2091_1316"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.600">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00508">
        <property type="entry name" value="Ribosomal_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001848">
        <property type="entry name" value="Ribosomal_S10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018268">
        <property type="entry name" value="Ribosomal_S10_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027486">
        <property type="entry name" value="Ribosomal_S10_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036838">
        <property type="entry name" value="Ribosomal_S10_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11700">
        <property type="entry name" value="PTHR11700"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00338">
        <property type="entry name" value="Ribosomal_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00971">
        <property type="entry name" value="RIBOSOMALS10"/>
    </dbReference>
    <dbReference type="SMART" id="SM01403">
        <property type="entry name" value="Ribosomal_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54999">
        <property type="entry name" value="SSF54999"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01049">
        <property type="entry name" value="rpsJ_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00361">
        <property type="entry name" value="RIBOSOMAL_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Ribosomal_S10" evidence="5">
        <location>
            <begin position="9"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC94143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="105" mass="11991" checksum="F28AFB39A3CC92A2" modified="2018-07-18" version="1">MSTPNQKIRIRLKAFDYKLIDQSALEIVDTAKRTGAIVKGPVPLPTRIQRFDVLRSPHVNKTSRDQFEIRTHQRLMDIVDPTEKTVDALMKLDLPAGVDVEIKLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2N7</accession>
    <name>A0A2S9H2N7_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Flavin prenyltransferase UbiX</fullName>
            <ecNumber evidence="5">2.5.1.129</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ubiX</name>
        <name evidence="7" type="ORF">S2091_0865</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>dimethylallyl phosphate + FMNH2 = phosphate + prenyl-FMNH2</text>
            <dbReference type="Rhea" id="RHEA:37743"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57618"/>
            <dbReference type="ChEBI" id="CHEBI:87467"/>
            <dbReference type="ChEBI" id="CHEBI:88052"/>
            <dbReference type="EC" id="2.5.1.129"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the UbiX/PAD1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.129" evidence="5"/>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94244">
        <property type="protein sequence ID" value="PRC94244"/>
        <property type="gene ID" value="S2091_0865"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106141">
        <property type="term" value="F:flavin prenyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1950">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01984">
        <property type="entry name" value="ubiX_pad"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036551">
        <property type="entry name" value="Flavin_trans-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003382">
        <property type="entry name" value="Flavoprotein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004507">
        <property type="entry name" value="UbiX-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43374">
        <property type="entry name" value="PTHR43374"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02441">
        <property type="entry name" value="Flavoprotein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52507">
        <property type="entry name" value="SSF52507"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00421">
        <property type="entry name" value="ubiX_pad"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3 5" id="KW-0288">FMN</keyword>
    <keyword evidence="1 5" id="KW-0637">Prenyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Flavoprotein" evidence="6">
        <location>
            <begin position="11"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="18"/>
            <end position="20"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="45"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="96"/>
            <end position="99"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="131"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="161"/>
        </location>
        <ligand>
            <name>dimethylallyl phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:88052"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="177"/>
        </location>
        <ligand>
            <name>dimethylallyl phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:88052"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC94244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="198" mass="21434" checksum="B60976C8FBC00A13" modified="2018-07-18" version="1">MTSPKSPPPARLIVAITGATGVVYAVRLLEVLRATTEIETHLVISEAGLMSLNQEVGMKKKQLEAMADVVYNVRDIGAAIASGSFQTMGMIIAPCSMKTLASVALGLSENLISRAADVTLKERRRLVLMVRETPFNLAHLRNMTSVTEMGGIIFPPLPSFYQHPASIAEMVDHSVGRVLDLFAIPHQLTPEWLGLKAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2P2</accession>
    <name>A0A2S9H2P2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_0851</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94230">
        <property type="protein sequence ID" value="PRC94230"/>
        <property type="gene ID" value="S2091_0851"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="2"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="5">
        <location>
            <begin position="127"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="127"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC94230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="229" mass="26399" checksum="CA7A953F74621387" modified="2018-07-18" version="1">MRIAVLEDDTNLLELVCSILNSAGHSAHPFSSGKEMLHNLRRENYDMLILDWQVPDLSGTEVMHWVREKLSSTIPILFMTSRSGEDDIVAGLAAGADDYMIKPIRRSELVARVQALLRRAYPNQHMPEHLEFGRYIFETRSARLSLSGQFIDVTQKEFDLALLLFRNLGRPLSRAYILEAVWSRDIEIPSRTMDTHISRVRNKLQLRPENGFRLAPVYSYGYRLEQIPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2T1</accession>
    <name>A0A2S9H2T1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0891</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94270">
        <property type="protein sequence ID" value="PRC94270"/>
        <property type="gene ID" value="S2091_0891"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07377">
        <property type="entry name" value="WHTH_GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00392">
        <property type="entry name" value="GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50949">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="2">
        <location>
            <begin position="18"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="483" mass="52944" checksum="C90A597A4A871B03" modified="2018-07-18" version="1">MHLGGIESLKTIVRDSAEPLYRQIYNRYRQAIANGSLAPGARVPSVRTLASELQLSRNTVEVAYDLLIGEGYLLARGQAGTIVSPDIVPQKVKNAMAQPSAPISGATFYHAPGEQSPKPFQLGLPALDLFPHKIWSSLTAKQLRLQSQYLSYPNPAGYQPLREAISAYLHISRGLDCTSEQVFIAPGYRGVISLIGRTLLQPLDQLWLEDPCFPPARYLLAELGAQIVPVPVDQDGLIVAQGRARAPHARFALVTPAHQSPLGVTLSMERRLELLAWAEQNNAWIIEDDYDSEYRYEGRPPPALASLDEAGNVLYVGTFSKVLSPALRLSYVVVPKTLISRFNQTCGKMHDGCPLLLQGVTADFINGGYFSRHLKKMRHAYTQRRQIVISSMREVLGERLQFSAPASGLNLLARLDANEDDVKLAQQAKRQNMAVEALSARCLDTPCGKGLLLGFANIASSQQALTLATQLKHSLETSGSIVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2U9</accession>
    <name>A0A2S9H2U9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0911</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94290">
        <property type="protein sequence ID" value="PRC94290"/>
        <property type="gene ID" value="S2091_0911"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010559">
        <property type="entry name" value="Sig_transdc_His_kin_internal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06580">
        <property type="entry name" value="His_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="41"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="73"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="106"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="domain" description="His_kinase" evidence="2">
        <location>
            <begin position="154"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06580"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="360" mass="40300" checksum="353DD1C290D67250" modified="2018-07-18" version="1">MSQPRASNFPNFWQLQAIGWTSLYLLILIAMIPVIGAPGMLRGNAIYVGVAFIESCVLWRLCRSAIAKQHSWLALEARAFVWSLCAGAFGALVVELGISDIRPLEWINWLTDCLQITVILFLWCSLYFSIKQWRHSVDERERRILAEQALREVRLNSLRYQLNPHFLFNALNVVSTLVAEGNGSGANRMLSQIAELLRSTLDSDGALSHTLAEEITLVNRYLDIEKVRFGERLQINIDIDDAVTDATVPTMLLQPLVENAIKHGINLQIDGGWLRIAAVSAEGRVSIIVENSGHRDLVVVPVKHASLGVGLANTRERLQTLYPDSHELELTWPEHGGCCIKIEIPLVKPVNPRQEILCES</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H343</accession>
    <name>A0A2S9H343_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative translation initiation inhibitor yjgF family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0907</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94286">
        <property type="protein sequence ID" value="PRC94286"/>
        <property type="gene ID" value="S2091_0907"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035959">
        <property type="entry name" value="RutC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006175">
        <property type="entry name" value="YjgF/YER057c/UK114"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11803">
        <property type="entry name" value="PTHR11803"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01042">
        <property type="entry name" value="Ribonuc_L-PSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55298">
        <property type="entry name" value="SSF55298"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="129" mass="14206" checksum="5DB57029A369A6D7" modified="2018-07-18" version="1">MQILQPPDWVRPRGYANGVVAKGSLVFTSGQLGWDGQGQFQSERYADQARQALQNIVTVLAQAGAKPEHIVRLTWYVTDRAAYLEQAKEVGQSYRELIGHFPTMSAFQVSALMVDGAKVEIEATAVIPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H348</accession>
    <name>A0A2S9H348_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Beta-ketoacyl synthase, N-terminal domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1011</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94390">
        <property type="protein sequence ID" value="PRC94390"/>
        <property type="gene ID" value="S2091_1011"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="333"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="domain" description="Ketoacyl_synth_N" evidence="2">
        <location>
            <begin position="69"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="364" mass="38740" checksum="9F088B76CFBDF66B" modified="2018-07-18" version="1">MTSLYIRTIGINSERCQDTEQLTANLGSGAVTPASADRYSTPAIRLNADGLAVIGREDRSILNEISTGVLNAIADALRHTGTEWMGEMNNVAVFTGTDGNELTFNAISSLIDRAGDEAIDRLGELKSLTNPINMMRMLSTNSTYHVSKRFGAQGGGYPNQSMSLSGLCALEDAVHTLRAGISERAVVVASGNMRSFDSLVVFGKLGLLDEAGGQQQVDPSYGAAALIVDSADAQDGPAPIAEVLAVQTLFAPEPFVTVQTWKTLFTTARERHGLPDLIVTYANGSRQLEETETAARNEVFGPIPTRNYKRYFGYTGKANNLLDLAATLADDSIPVGATVLLCGAGFGFGIGYLLVRKLGKPVLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H350</accession>
    <name>A0A2S9H350_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Sulfotransferase domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_0984</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94363">
        <property type="protein sequence ID" value="PRC94363"/>
        <property type="gene ID" value="S2091_0984"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008476">
        <property type="term" value="F:protein-tyrosine sulfotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006478">
        <property type="term" value="P:peptidyl-tyrosine sulfation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026634">
        <property type="entry name" value="TPST"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12788">
        <property type="entry name" value="PTHR12788"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="1 5" id="KW-0808">Transferase</keyword>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="60"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="94"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="128"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="162"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC94363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="548" mass="62344" checksum="0DE59E33721D9254" modified="2018-07-18" version="1">MHDEQSKLPNIPSIKTSDNLLASEPTTQEIDALVVLFTQRRYAEAETTAIALIARFPKHGFAWKALGTVHRRQGRKDEAVAALKNAAELMPEDAEAHNNLGNALREQGRSIDAETLYRHALELRPTYVEAHYNLGCVLKDQKRVEEAETQYRRALELNPDYVPAHNNLGNVLKEQGRLEEACASLETAITIKPNFIESHYSLSSLKTYHENDPHQDMLEALLGEVKAMPVEARIRYWFALGKMREDVGLYDASFAAYQEANRLQHALLPFDETADEAAHKRMMDVFSKEFLAQRARPIDIGKAPIFIVGMPRSGTSLLEQILSSYPGVFGAGELSDMSEVITAALPDAAFERFPDVVPDFSADDFKRLGEHYSERVARLAPTATHITDKMPANYYYVGMIYLMFPNAKIIHAMREPMDSCFSCYSRLFNMKNLAFSYDQGTLGRSYVRYIKLMRHWHEVLPPGTILDLRYEDMVADTEGQARRLLDYIGLPWNDQCLAFHENKRRVKTASAAQVRKPIYKTSLARWKRYEGHLGELFGLVKDYRDVGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H384</accession>
    <name>A0A2S9H384_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1038</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94417">
        <property type="protein sequence ID" value="PRC94417"/>
        <property type="gene ID" value="S2091_1038"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="50" mass="5942" checksum="2038BE08E084E139" modified="2018-07-18" version="1">MLRGHTKEDIDTLLRNENGVAQDNWMWLVREVEKVRGERLINEAGELRHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3A2</accession>
    <name>A0A2S9H3A2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1086</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94465">
        <property type="protein sequence ID" value="PRC94465"/>
        <property type="gene ID" value="S2091_1086"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041492">
        <property type="entry name" value="HAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13419">
        <property type="entry name" value="HAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01509">
        <property type="entry name" value="HAD-SF-IA-v3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="203" mass="23712" checksum="AAB4101B509BF993" modified="2018-07-18" version="1">MNAYMADLLGDGKSPADAATVNAARTLYWKKYGATLLGLINHHNVNPAEFLQQAHHFDDLPNLLRYESGLKRLLKRLPGRKILFTNAPRQYSRQVLQHLGLHRHFDQHISIESMRVHGKLRPKPSRWLLRKLLAKQKLSARHCVLIEDTRENLRTAKQLGMKTVWITQYLKEKKRFTRAHYIDLKIRSIKQIPTQLSRLSLNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3B2</accession>
    <name>A0A2S9H3B2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1095</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94474">
        <property type="protein sequence ID" value="PRC94474"/>
        <property type="gene ID" value="S2091_1095"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="98" mass="9885" checksum="5F7D1FFFA5AC581B" modified="2018-07-18" version="1">MPVYLIWTNIKTGESYFDAAGVAAGVEAAAALWCFLCFFTGVEAGVLAGIAAGVAAGAGVEAAAGVAGAAAKAETANKLATNAEIMVFMLDPIKFRLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3F1</accession>
    <name>A0A2S9H3F1_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HGSNAT_cat domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0512</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94509">
        <property type="protein sequence ID" value="PRC94509"/>
        <property type="gene ID" value="S2091_0512"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012429">
        <property type="entry name" value="HGSNAT_cat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07786">
        <property type="entry name" value="HGSNAT_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="110"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="138"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="219"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="248"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="279"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="323"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="domain" description="HGSNAT_cat" evidence="2">
        <location>
            <begin position="3"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="352" mass="38405" checksum="13EEBCBAFFC873F4" modified="2018-07-18" version="1">MARFSSIDALRGITVAAMLLVNNAGDWDHVYPWMEHAAWNGCNPADFIFPFFLLIVGVSLNLALASKLDAGSNRPQLSKSVVFRGARIVLLGLVLHLIACWLIDGRAFRVMGVLQRIGLCFALVGLCHIWIRDARIQWGIIAAILLGYWALLGGVVEPRFNLVDKIDTLLLGARAYQFDPATGIAHDPEGILSTLPALATVLLGVRVGEWLRTGQLQKMIIGGIVSISLGGVWSLNFPLNKQLWSSSFVLWTAGFGMLAISLMHYLIDQKNWPALGKSFGINAIAAYAGSWIGICLLYGTGAFQPLYTHLFAQPLTGSVSPEFASLMFSCAFTGIFALLLKCMEQRGLRIVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3H3</accession>
    <name>A0A2S9H3H3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-17-dioic acid hydratase (Catechol pathway)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0531</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94528">
        <property type="protein sequence ID" value="PRC94528"/>
        <property type="gene ID" value="S2091_0531"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.850.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011234">
        <property type="entry name" value="Fumarylacetoacetase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036663">
        <property type="entry name" value="Fumarylacetoacetase_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01557">
        <property type="entry name" value="FAA_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56529">
        <property type="entry name" value="SSF56529"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAA_hydrolase" evidence="1">
        <location>
            <begin position="26"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="234" mass="25250" checksum="FD158D978834FBF4" modified="2018-07-18" version="1">MSYIFPPEAVTALKVAASSDLFAVRRVYCVGRNYAAHAREMGSDPTREAPFFFCKPANAVTPITDGQTLELAYPGVTTNFHHEIELVVAIGKAGRDIPVAQANAHVWGYAVGLDMTRRDLQGQMKDKGKPWEIGKAFDHSAPIGNLYPVDQVGLLNINKAAIYLKVNGSDKQRSNIDQMTWSVPEIISHLSSYFELKPGDLIMTGTPEGVGAVLVGDVLEGGIAGLGGIRVRVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3K2</accession>
    <name>A0A2S9H3K2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC-type spermidine/putrescine transport system permease component I</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_0567</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94564">
        <property type="protein sequence ID" value="PRC94564"/>
        <property type="gene ID" value="S2091_0567"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="44"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="76"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="126"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="181"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="225"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="40"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC94564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="258" mass="28870" checksum="4BE9DA2FBC1E2BD1" modified="2018-07-18" version="1">MEISDPLGTLMTYVDGVLDIKIKFSNYLFLGQDDLYIVTYLNSIKYALFTTVLCLIIGYPFAYFMARAQPSARATLMMMVMLPFWTSFLLRIYAWKGMLSTHGVLNNFLMSVGAIDAPLHMMNTPFSLMIGMVYSYLPFMILPLFTNLSKLDVRFIEAAADLGSTPWSTFWRVTVPLSKSGIIAGSMLVFIPCVGEFVIPDLLGGPGTPMIGHVMWDEFFSNNDWPMASAVTVVVILLILVPMGILNKYQSEEERGNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3M2</accession>
    <name>A0A2S9H3M2_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF4440 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0585</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94582">
        <property type="protein sequence ID" value="PRC94582"/>
        <property type="gene ID" value="S2091_0585"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027843">
        <property type="entry name" value="DUF4440"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011944">
        <property type="entry name" value="Steroid_delta5-4_isomerase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14534">
        <property type="entry name" value="DUF4440"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02246">
        <property type="entry name" value="TIGR02246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015412589" description="DUF4440 domain-containing protein" evidence="1">
        <location>
            <begin position="28"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4440" evidence="2">
        <location>
            <begin position="40"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="166" mass="18332" checksum="5513136F1B32D8AC" modified="2018-07-18" version="1">MNIFIRNMVASTAFITFTMLLSHVTVAAESNDSIDTKAIRLQLQRYEQALNDSDAESVMQLYAEDAVAMPQNSNPLVGRDSLRAAVTAGFKAVKLNVKFVIDEIQPLSSAWAYARTRSTGTINVLGSDGLPNLEANQEIFLFHKESDGEWRVARYIFSTTNPAAIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3N4</accession>
    <name>A0A2S9H3N4_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">GDT1 family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_1097</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Membrane</location>
            <topology evidence="1 6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the GDT1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94476">
        <property type="protein sequence ID" value="PRC94476"/>
        <property type="gene ID" value="S2091_1097"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001727">
        <property type="entry name" value="Gdt1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12608">
        <property type="entry name" value="PTHR12608"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01169">
        <property type="entry name" value="UPF0016"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="38"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="68"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="98"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="135"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="168"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU365102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC94476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="196" mass="20563" checksum="1258EB2B5597B5BF" modified="2018-07-18" version="1">MLQPFLVSTSVVALAEIGDKTQLLSLVLAARYRKPLPIALGVLVATLANHAGAGGLGTLLSGILNPTVLNWAVVASFVLMAGWILIPDKLDEGELAMPKKAMGVFGTTVFVFFLAEMGDKTQIVTIALAARYHDFFGVVSGSTLGMILANVPVIYLGSRFANKLPIKAVHIIASIIFVVLGGLALRNAITGTAFAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3N5</accession>
    <name>A0A2S9H3N5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0580</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94577">
        <property type="protein sequence ID" value="PRC94577"/>
        <property type="gene ID" value="S2091_0580"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="58"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="83"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="107" mass="11495" checksum="20A080564E9EB91B" modified="2018-07-18" version="1">MLGLNLTAYINWFIGNVAGALVATLIPPHFLHSLQFALVAMFIGLIVLQITGTKNKRLQISVALLAVVLVEPFAMLFGKNFSVILTAITASFIGMGVMAWKSTTKSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3P3</accession>
    <name>A0A2S9H3P3_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Homoserine O-succinyltransferase</fullName>
            <shortName evidence="3">HST</shortName>
            <ecNumber evidence="3">2.3.1.46</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Homoserine transsuccinylase</fullName>
            <shortName evidence="3">HTS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">metXS</name>
        <name evidence="6" type="ORF">S2091_0602</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>L-homoserine + succinyl-CoA = CoA + O-succinyl-L-homoserine</text>
            <dbReference type="Rhea" id="RHEA:22008"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57292"/>
            <dbReference type="ChEBI" id="CHEBI:57476"/>
            <dbReference type="ChEBI" id="CHEBI:57661"/>
            <dbReference type="EC" id="2.3.1.46"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; O-succinyl-L-homoserine from L-homoserine: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the AB hydrolase superfamily. MetX family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.46" evidence="3"/>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94599">
        <property type="protein sequence ID" value="PRC94599"/>
        <property type="gene ID" value="S2091_0602"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00051">
        <property type="reaction ID" value="UER00075"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008899">
        <property type="term" value="F:homoserine O-succinyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009086">
        <property type="term" value="P:methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00296">
        <property type="entry name" value="MetX_acyltransf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008220">
        <property type="entry name" value="HAT_MetX-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32268">
        <property type="entry name" value="PTHR32268"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000443">
        <property type="entry name" value="Homoser_Ac_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01392">
        <property type="entry name" value="homoserO_Ac_trn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 3" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="5">
        <location>
            <begin position="45"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="3 4">
        <location>
            <position position="151"/>
        </location>
    </feature>
    <feature type="active site" evidence="3 4">
        <location>
            <position position="316"/>
        </location>
    </feature>
    <feature type="active site" evidence="3 4">
        <location>
            <position position="349"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="221"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="350"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Important for acyl-CoA specificity" evidence="3">
        <location>
            <position position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000443-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC94599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="375" mass="41444" checksum="F035E9B567104B42" modified="2018-07-18" version="1">MSSVAIVAPQTHTFSEPLTLQSGAAIAEYTLMYETYGQLNAAKSNAVLICHALNASHHVAGVYADEPDNVGWWDNMIGPGKPLDTNHFFVIGVNNLGSCFGSTGPMHTNPATGKPYGADFPVVTVEDWVNAQARLADVLGITQFAAVMGGSLGGMQALSWSTLFPERLRHCVVIASTAKLSAQNIAFNDVARQAIISDPDFHGGDFYAHSVVPKSGLRVARMVGHITYLSNDDMAEKFGRDLKCDDYQFGFGVDFEIESYLRYQGDKFSAYFDANTYLLITKALDYFDPARRFGGDLTQALANTQAQFLLVSFSTDWRFSPERSREIVRALISNKRRVTYAEIDAPHGHDAFLLEDARYMNLVRTYFERIAKEQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3S2</accession>
    <name>A0A2S9H3S2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">TPR repeat</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0620</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94617">
        <property type="protein sequence ID" value="PRC94617"/>
        <property type="gene ID" value="S2091_0620"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015711405" evidence="2">
        <location>
            <begin position="22"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="205"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="239"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="388" mass="44612" checksum="30F95450EFA4B22F" modified="2018-07-18" version="1">MPIFKYLTTLLVLFLSACSSINPPPGVTPIPIEQLAWQDAFFAYDPSLVTIHRQDLFYLNPALTAQINAVLARRMAMPARLNQLLTIVFGSTHTIFPYRAGHSTIASETWKNKYGDCISLTMLSYAVGKALQLPIEMQEVESATLFDRREQIDFINEHVNIIVNNSQQIELKEKTLGARDFVIDFEPEFAVFERGRSLTEDGIAARFYNNLASEYFANDQPRLAYAYFKAAIYIDPSYAESYSNLAQLYRSKDLLADAEKMLRYCLQINPNAEIAMTSLRDLLTQQNRTDEAQHYTDLLKQWQYKNPYHWLRLGIYQINHQQFSDAVDSLEHAAEITHGFEEVHANLALAYWHNKQEKKAREQLNILTKLNPNNARISVLNKMFNTPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3S3</accession>
    <name>A0A2S9H3S3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0635</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94632">
        <property type="protein sequence ID" value="PRC94632"/>
        <property type="gene ID" value="S2091_0635"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="4"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="283" mass="31736" checksum="97906DBCFCB6728B" modified="2018-07-18" version="1">MNSPDWNDLRFFLALIDAGTLSGAARMLGVEHTTVARRIDALEAPLMVRLFDRFPKGWSLTSAGIALVPHARQLEEDMHALMRAATGSATLSGVVRLSAPPALAAYLLAPRLRAVLSRLPEIEIELLGESREADLMRRDADIALRFRRPSAPGLAVRTLTTIPYSLYASAQYLSQRTPQQWEFLGYNESLRDAPQQLWLDKIRGERRYALRSNDLGALFQAAVAGCGVTVLPTYFEKQHSELVRIESDCPVKRKLWIVMHEDVRRSARVRAIADEVISLFDNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H400</accession>
    <name>A0A2S9H400_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NAD(P)-binding Rossmann-like domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94697">
        <property type="protein sequence ID" value="PRC94697"/>
        <property type="gene ID" value="S2091_0700"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015399504" evidence="1">
        <location>
            <begin position="18"/>
            <end position="538"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="538" mass="59828" checksum="E1D4E367DF4F0D21" modified="2018-07-18" version="1">MNRRSFLLWAGASSAVAMGSAAEFWRWQEITTDVNYPGMAEGHFLRDRHKLPPPTEIIQTDVVVLGSGIGGLTAAWKMNKEGLNDFLVIDGPQVYGNAAGGHFGDLAYPTGAHYLPVPSTESFHVREILTDLGIILRNPMSEKPYYDERYLLHAPEERLLFNGRWQEGVIPNEGVPPDELKEHSRFFKEIERLRHLRDSNGKRIFAIPSTLSSTDPEWQALDSITFKAWLEKNGYSSPTLHWYLNYCCRDDYGTRYDKVSAWAGLHYYCSRSGKAENAESGAWLTWPGGLSPLAEAMDKAAGSRRKSGTAVSLKTTADGVEAHCFELINGIPKTFIVRARKAICAMPLYVASRVVESIQDYGFDPALHLPTYAPWLVANFLMNDFPHELPDAPLSWDNVVYQEPGLGYVVSTHQDIRITPPPKTVFSAYVALSDQSPDAARKWMARVTAKELLAAASADLKAAYGWKFASCVERVDITLRGHAMAVPLPTFRSNPGLKALRELDGPILFAHADLSGFSVFEEAAWWGYRAAGLALKQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H449</accession>
    <name>A0A2S9H449_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0734</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94731">
        <property type="protein sequence ID" value="PRC94731"/>
        <property type="gene ID" value="S2091_0734"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="38" mass="4306" checksum="FAB5751FE5D60898" modified="2018-07-18" version="1">MIIEYPAYIAITLQLGATLRKLNCLMNLWIGTQIQGLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H475</accession>
    <name>A0A2S9H475_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Penicillin-binding protein 1A</fullName>
            <ecNumber evidence="7">2.4.1.129</ecNumber>
            <ecNumber evidence="6">3.4.16.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="27" type="ORF">S2091_0780</name>
    </gene>
    <organism evidence="27 28">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="27 28" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="27 28">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="21">
            <text>[GlcNAc-(1-&gt;4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n)-di-trans,octa-cis-undecaprenyl diphosphate + beta-D-GlcNAc-(1-&gt;4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate = [GlcNAc-(1-&gt;4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n+1)-di-trans-octa-cis-undecaprenyl diphosphate + di-trans,octa-cis-undecaprenyl diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23708"/>
            <dbReference type="Rhea" id="RHEA-COMP:9602"/>
            <dbReference type="Rhea" id="RHEA-COMP:9603"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58405"/>
            <dbReference type="ChEBI" id="CHEBI:60033"/>
            <dbReference type="ChEBI" id="CHEBI:78435"/>
            <dbReference type="EC" id="2.4.1.129"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">In the C-terminal section; belongs to the transpeptidase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">In the N-terminal section; belongs to the glycosyltransferase 51 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="27">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.129" evidence="7"/>
    <dbReference type="EC" id="3.4.16.4" evidence="6"/>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94777">
        <property type="protein sequence ID" value="PRC94777"/>
        <property type="gene ID" value="S2091_0780"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008658">
        <property type="term" value="F:penicillin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008955">
        <property type="term" value="F:peptidoglycan glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009002">
        <property type="term" value="F:serine-type D-Ala-D-Ala carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046677">
        <property type="term" value="P:response to antibiotic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3810.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001264">
        <property type="entry name" value="Glyco_trans_51"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023346">
        <property type="entry name" value="Lysozyme-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036950">
        <property type="entry name" value="PBP_transglycosylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031376">
        <property type="entry name" value="PCB_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001460">
        <property type="entry name" value="PCN-bd_Tpept"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17092">
        <property type="entry name" value="PCB_OB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00912">
        <property type="entry name" value="Transgly"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00905">
        <property type="entry name" value="Transpeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53955">
        <property type="entry name" value="SSF53955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="18" id="KW-0046">Antibiotic resistance</keyword>
    <keyword evidence="9" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="14" id="KW-0133">Cell shape</keyword>
    <keyword evidence="20" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="11 27" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="13 27" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="23" id="KW-0472">Membrane</keyword>
    <keyword evidence="19" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="16" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="10" id="KW-0645">Protease</keyword>
    <keyword evidence="28" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="15" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="27" id="KW-0808">Transferase</keyword>
    <keyword evidence="12 23" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="17 23" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="23">
        <location>
            <begin position="30"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="domain" description="Transgly" evidence="25">
        <location>
            <begin position="83"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="domain" description="PCB_OB" evidence="26">
        <location>
            <begin position="342"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="domain" description="Transpeptidase" evidence="24">
        <location>
            <begin position="451"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="22">
        <location>
            <begin position="772"/>
            <end position="794"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00007739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00012555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00018638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00023251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00023988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="24">
        <source>
            <dbReference type="Pfam" id="PF00905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="25">
        <source>
            <dbReference type="Pfam" id="PF00912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="26">
        <source>
            <dbReference type="Pfam" id="PF17092"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="27">
        <source>
            <dbReference type="EMBL" id="PRC94777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="28">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="794" mass="86611" checksum="C252B3078E4BCBA3" modified="2018-07-18" version="1">MTTDSHSGTSKAARSNSLNSARKRHPAVNIALGFVVFLVGIALIGVLVVVFALTLAYPNLPDLDSITSYRPKIPLRVFSADNVLLGEFGEERRSVMQLKDIPEIMKKTLLATEDDRFYEHGGVDYLGITRAALHNLMGGSKQGASTITQQVARNFFLSSEQTFKRKIYEVLMAWKIEQNLSKDQILEIYMNQIYLGQRAYGFASASKIYFGKKLQDITIAEAAMLAGLPKAPGASNPISNPKRAKIRQQAILQRMLQQGYITPAQYEQAKNEEIHVGNNVNVYGTHAEYVTEMARQMVYEQFKEETYTLGLNVYTTVTKADQDAAYLSLRRGVMDYVKKHAYRGPEGYLEIPADKSDAEDEIESALAEHPDSDDIVAAVVLEATPKNVRAVMSNGDEINITGNGLTFAASGLSAATAATAPKRRIIRGSIIRVSLEDKTWSITQMPEVESAFVAASTTDGAIRALVGGFDFNRNKFNHVTQAWRQPGSSFKPFIYSASLEKGLSPATMINDAPISFGAGQTGGQAWEPKNYDSKYEGLMTMRKGLTKSKNMISIRILNKIGAKYGQQYVTRFGFDADKNPPYLTLALGAGAVTPLQMAGAYSVFANGGYKINPYLISKITDSNGKVLSETKPELAGNEANRVIDERNAFLIDSMLKDVVRYGTAARAMALKRTDLAGKTGTTNDSIDAWFAGYQAKLVGIAWMGFDQPKNLGNRETGGGLSLPIWMGFMQTALKNIPMEERAVPNGIIQADGDYFYVENPPGSGVQVLDTPEAIDPNTAPVGAEPTATAPAATN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4D4</accession>
    <name>A0A2S9H4D4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0739</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94736">
        <property type="protein sequence ID" value="PRC94736"/>
        <property type="gene ID" value="S2091_0739"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="177" mass="19104" checksum="470B157DFCD5C474" modified="2018-07-18" version="1">MKNIHSFVVATVLGLVCFHARAKEVSSHRLCVANDEPVFSCTLQGNTHKMVSLCASPASAQGERTFRYLFGYPSKIELTYPSSDSDADSFTLTHLVYAGATGGSAYAFTNDGYKYILYSIEGTGLKRSGLLVQHVGQLHAASDLNCTPSALVESGDELIPKWKADQDIDAHGLPSTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4G4</accession>
    <name>A0A2S9H4G4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HypoxanDNAglyco: DNA-deoxyinosine glycosylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0069</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94874">
        <property type="protein sequence ID" value="PRC94874"/>
        <property type="gene ID" value="S2091_0069"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026353">
        <property type="entry name" value="Hypoxan-DNA_Glyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005122">
        <property type="entry name" value="Uracil-DNA_glycosylase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036895">
        <property type="entry name" value="Uracil-DNA_glycosylase-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03167">
        <property type="entry name" value="UDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00986">
        <property type="entry name" value="UDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52141">
        <property type="entry name" value="SSF52141"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04274">
        <property type="entry name" value="hypoxanDNAglyco"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UDG" evidence="1">
        <location>
            <begin position="22"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="177" mass="19496" checksum="578B76213F91E515" modified="2018-07-18" version="1">MCVSPAVLIVNTHPMPKKRSFAPIVNEHTRLLVLGSLPGEKSLAQSQYYGNSQNRFWMLMSEVVKVDLVALAYPERLEALLANGVGLWDVVAEAHRDGSLDSKIRDQTNNDLRGLLSTLPQLSSIAFNGGTAARLGLKALQGQAECYRIIQLPSSSPAYTIPYVQKLDAWRCLQDCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4L3</accession>
    <name>A0A2S9H4L3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0119</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94924">
        <property type="protein sequence ID" value="PRC94924"/>
        <property type="gene ID" value="S2091_0119"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="174" mass="18574" checksum="71B0F6B3B0528863" modified="2018-07-18" version="1">MDYDFTLKFKLPDTNTDADAILEKLGAAGCDDALVGLGIPGRIALDFTRNANSAQAAILSALADVKLAIPDAKLLEVGPDFVGITDVAEVIGVSRQNIRKLMVTNAATFPAAVHDGSASIWHLALVLQWLQARGSYQIAQNVFDVSRMAMQVNIAKEAQLLSADLGKNLRELIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4N7</accession>
    <name>A0A2S9H4N7_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NADP-specific glutamate dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">S2091_0137</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:11612"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.4.1.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the Glu/Leu/Phe/Val dehydrogenases family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94942">
        <property type="protein sequence ID" value="PRC94942"/>
        <property type="gene ID" value="S2091_0137"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016639">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:cellular amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminiacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006095">
        <property type="entry name" value="Glu/Leu/Phe/Val_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033524">
        <property type="entry name" value="Glu/Leu/Phe/Val_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006096">
        <property type="entry name" value="Glu/Leu/Phe/Val_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006097">
        <property type="entry name" value="Glu/Leu/Phe/Val_DH_dimer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016211">
        <property type="entry name" value="Glu/Phe/Leu/Val_DH_bac/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42722">
        <property type="entry name" value="PTHR42722"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00208">
        <property type="entry name" value="ELFV_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02812">
        <property type="entry name" value="ELFV_dehydrog_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000188">
        <property type="entry name" value="Phe_leu_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00082">
        <property type="entry name" value="GLFDHDRGNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00839">
        <property type="entry name" value="ELFV_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="SSF53223"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00074">
        <property type="entry name" value="GLFV_DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0520">NAD</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ELFV_dehydrog" evidence="9">
        <location>
            <begin position="142"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="6">
        <location>
            <position position="82"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="178"/>
            <end position="183"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000188-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000188-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC94942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="343" mass="36291" checksum="F81021B75E16C26A" modified="2018-07-18" version="1">MTAFVFNEPNFDDHEQVVFVSEPKSGLKAIIAVHNTNLGPAMGGCRMWSYMNEAAAINDVLRLSRGMTYKNAVAGLPIGGGKSVIIGNPKTDKTPALFEALGEALERLGGRYVTAEDIGTSPADMANVSNKTKFVAGLGDSGDPSPFTALGCFVGAQAAVKFHLKRDNMEGLVVAVQGLGHVGYDYARRLHAAGAKLIVADIDTAAVERARAEFGAEVVSVDAIYDVAADIYAPCALGATLNPLTLSRIKASIVAGAANNQLATADVGDMMRQKGMLYVPDFVINAGGIIKVCYEYLNKPEADVEAHVREIGATLTEVFERAAHEGLSTSVVADRVAEARFKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4S5</accession>
    <name>A0A2S9H4S5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_0163</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94968">
        <property type="protein sequence ID" value="PRC94968"/>
        <property type="gene ID" value="S2091_0163"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="3"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="5">
        <location>
            <begin position="129"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="129"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC94968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="236" mass="26788" checksum="A4D950C89BEB72AE" modified="2018-07-18" version="1">MRKILIVDDDQKTRTLLKTYLEKNQYEVRLAHNGESFLSEFQRYTDELSLVILDVMLPDTDGFALCKIVRQRSNVPIIMLTASSDETDRVVGLELGADDYIGKPYSPRELLARIKAIHRRTGLENTAPPRFYRFLGFTLDCVERTVVDAHGELVALTGLDFQLLKYFVEHPGDILDRGILSEETRGRDSGPLDRSLDVQISRLRLRLNDDGKQPFLIKTVRGAGYVFSADVIASQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4V9</accession>
    <name>A0A2S9H4V9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Acyl-CoA dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_0220</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95025">
        <property type="protein sequence ID" value="PRC95025"/>
        <property type="gene ID" value="S2091_0220"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016627">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="SSF47203"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="SSF56645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA_dh_N" evidence="7">
        <location>
            <begin position="11"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_M" evidence="6">
        <location>
            <begin position="143"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_1" evidence="5">
        <location>
            <begin position="258"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC95025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="416" mass="45104" checksum="E70D74437B720193" modified="2018-07-18" version="1">MNFAFSSTAQSYINRLQDFMAEHVIPAEAVYFSQLKRGERPWVVPPVMADLKARAKQAGLWNLFLAADEHNKVHGAGLTGLIGLSNADYAPLAEIMGRSFIAPEVFNCNAPDTGNMEVLVKYGSAEQQQRWLQPLLSGEIRSAFCMTEPDVASSDATNMQATAIVEGDEVVLNGVKWWSTGIGHPDCRVVIFMGLSDLNPKAPKHLRHSMVLVPMDTPGVKIERMLSVFGDQDEPYGHGEVSFTNVRLPVSSIIAGAGRGFEIAQGRLGPGRIHHCMRVIGAAERALELMCKRAVRRVAFGQPLADLGGNSDIIANARIAIEQARLLTLKAAWMIDTVGVKAAMSEIAQIKVVAPNVAQMVIDQAIQIFGAAGVGADTPLAAMYANARILRLADGPDEVHRSMIAKLELKPYRNSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4W2</accession>
    <name>A0A2S9H4W2_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Probable potassium transport system protein kup</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">kup</name>
        <name evidence="12" type="ORF">S2091_0214</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Transport of potassium into the cell.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cell membrane</location>
            <topology evidence="11">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the HAK/KUP transporter (TC 2.A.72) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95019">
        <property type="protein sequence ID" value="PRC95019"/>
        <property type="gene ID" value="S2091_0214"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015079">
        <property type="term" value="F:potassium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01522">
        <property type="entry name" value="Kup"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003855">
        <property type="entry name" value="K+_transporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023051">
        <property type="entry name" value="K+_uptake_low_affin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30540">
        <property type="entry name" value="PTHR30540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02705">
        <property type="entry name" value="K_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 11" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9 11" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 11" id="KW-0630">Potassium</keyword>
    <keyword evidence="5 11" id="KW-0633">Potassium transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="47"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="99"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="135"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="166"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="212"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="242"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="283"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="329"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="360"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="389"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="420"/>
            <end position="439"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01522"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PRC95019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="628" mass="68803" checksum="A6BB025173ECBA9E" modified="2018-07-18" version="1">MPALALAALGIVFGDLGTSPLYALQETFHPQRGVAASAENVMGAVSLFLWALIIMVSLKYVLVLMRADNRGEGGILALLTLLIGERSCHQHTGRRAKRWIFLALIGTAMLYGDGVITPAISVLSAIEGLQIATPAFQPYVVPTTIVILIGLFAIQPFGSGKVGIIFGPILLIWFLVIAALGLHTLWQNPAILGAINPMHGIRFFERNGGQGFIALGAVVLCLTGGEALYADMGHFGRRPIQLAWYGLALPSLALNYLGQGALLLSNPSVADRPFYSMVPTWGLYPMVALAALATIVASQALISAVFSLTRQAAQLGYSPRVEVIHTSGAMIGQVYLPTLNWLLMIGTIAIVLLFKTSDNLAAAFGLAVSTTMAITTILFAALARVRWHWSWWSVAAVAGVFFIADVAFVLANTLKFLDGGWLPLALGIAVFSIMASWYAERAILAKERRERAMPLGSFIDNLAMSPPHRVAGVAVFLTEEADVVPVELLHHLKHNQVLHERVVLLTLITEEVPRVQKEHSLSVDELPLGFISIIARFGFMEEPNVPNTLDLTSKLADYELFEPLSTTYFLGHQTLVLPRRRQWQWRGWLHRWSQSLFILLSRNEHNAILRFGLPPNRVVELGQHLEME</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H549</accession>
    <name>A0A2S9H549_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major Facilitator Superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_0304</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95109">
        <property type="protein sequence ID" value="PRC95109"/>
        <property type="gene ID" value="S2091_0304"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="7"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="41"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="73"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="103"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="135"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="161"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="208"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="246"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="276"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="304"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="337"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="376"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="7"/>
            <end position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC95109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="408" mass="43705" checksum="ECCD5CDD74E1FCFC" modified="2018-07-18" version="1">MKTALRVFIIFSLGYFVSYLVRGINLPLAPLLSSELGLSPAQLGLLTSLYFFAFAACQLPLGVMLDRFGPRRVLMPLLVLAALGALVSAYAEGFSGLLMGRLLLGVGTSACMMAGLKAIISWFDARHLPLMNGALYAIGGLGAVAVGVPVEWALSVTSWRVLFVTVAMLIGLIVLALFWLVPERSEAQAVSPIGSQWRGIAEVFRSPVFVRIAPLAMVSQGVFLGVQGLWAGPYLRDVTQLSPGAAANMVTIMGLAMVVGAVGFGWLGRRLHSHGIALQSTAVVGMLAFMLAQLLIVLEVPLPVWLLWSFYGFSGTAGVLCYASLAQEFPAQLAGRVSTLLTLALFIGAFIVQYGFGLLLNIWPHGDVFNAALAHRANWILALGVQACALLWFYRGKADRLMLNHVKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H590</accession>
    <name>A0A2S9H590_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0231</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95036">
        <property type="protein sequence ID" value="PRC95036"/>
        <property type="gene ID" value="S2091_0231"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="108"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="108"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC95036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="185" mass="20469" checksum="A8C34EE09AC16FFD" modified="2018-07-18" version="1">MNTKRNKRWNGDVATLSAAYLKNVIEKMQAYGDNAQFSTNGTIHGPNYQVINTAGKKMSFDSGNLLIQTDEEEFTSKISATIYSLEQVKALLVRINSPLVKTTATRTRRVASSTSVGTTSSPRGGSALAKAKEQIAIQKYEYYKTNRATLPSDIREHSEEITRMMESGISAEEAFTEASKLCFDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H598</accession>
    <name>A0A2S9H598_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">4-hydroxy-tetrahydrodipicolinate reductase</fullName>
            <shortName evidence="9">HTPA reductase</shortName>
            <ecNumber evidence="9">1.17.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">dapB</name>
        <name evidence="12" type="ORF">S2091_0298</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>(S)-2,3,4,5-tetrahydrodipicolinate + H2O + NAD(+) = (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:35323"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16845"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:67139"/>
            <dbReference type="EC" id="1.17.1.8"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>(S)-2,3,4,5-tetrahydrodipicolinate + H2O + NADP(+) = (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:35331"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16845"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:67139"/>
            <dbReference type="EC" id="1.17.1.8"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="9">Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; (S)-tetrahydrodipicolinate from L-aspartate: step 4/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the DapB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.</text>
    </comment>
    <dbReference type="EC" id="1.17.1.8" evidence="9"/>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95103">
        <property type="protein sequence ID" value="PRC95103"/>
        <property type="gene ID" value="S2091_0298"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00034">
        <property type="reaction ID" value="UER00018"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008839">
        <property type="term" value="F:4-hydroxy-tetrahydrodipicolinate reductase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016726">
        <property type="term" value="F:oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019877">
        <property type="term" value="P:diaminopimelate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00102">
        <property type="entry name" value="DapB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022663">
        <property type="entry name" value="DapB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000846">
        <property type="entry name" value="DapB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022664">
        <property type="entry name" value="DapB_N_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023940">
        <property type="entry name" value="DHDPR_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20836">
        <property type="entry name" value="PTHR20836"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05173">
        <property type="entry name" value="DapB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01113">
        <property type="entry name" value="DapB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000161">
        <property type="entry name" value="DHPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00036">
        <property type="entry name" value="dapB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01298">
        <property type="entry name" value="DAPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 9" id="KW-0220">Diaminopimelate biosynthesis</keyword>
    <keyword evidence="8 9" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="7 9" id="KW-0520">NAD</keyword>
    <keyword evidence="4 9" id="KW-0521">NADP</keyword>
    <keyword evidence="6 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DapB_N" evidence="10">
        <location>
            <begin position="6"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="domain" description="DapB_C" evidence="11">
        <location>
            <begin position="130"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="(S)-2,3,4,5-tetrahydrodipicolinate binding" evidence="9">
        <location>
            <begin position="167"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="9">
        <location>
            <position position="157"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="9">
        <location>
            <position position="161"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="11"/>
            <end position="16"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="100"/>
            <end position="102"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="124"/>
            <end position="127"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="158"/>
        </location>
        <ligand>
            <name>(S)-2,3,4,5-tetrahydrodipicolinate</name>
            <dbReference type="ChEBI" id="CHEBI:16845"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF05173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PRC95103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="269" mass="28135" checksum="C9CC3ED68B6CF1F9" modified="2018-07-18" version="1">MNNLLKIAIAGASGRMGHMLIEAVNAADDTQLAGALDVASSPAIGQDAAAFSGKLSGVAISADLSAGLADADYLIDFTRPEGTLKYLEYCAEHGIKMIIGTTGFDDAGKAAIAEAAKKTAIVFAPNMSVGVTVTMKLLELAAKSFAEGYDIEIIEAHHRHKVDAPSGTALKMGEVIASAIGRDLNEVAVYAREGETGERDPSSIGFATIRGGDIVGDHTVLFAGIGERVEISHKSSSRVTYANGSLRAARFLQDKQHGLFDMNDVIGLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5P9</accession>
    <name>A0A2S9H5P9_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 13 14">UDP-N-acetylmuramoylalanine--D-glutamate ligase</fullName>
            <ecNumber evidence="5 13 14">6.3.2.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">D-glutamic acid-adding enzyme</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">murD</name>
        <name evidence="17" type="ORF">S2091_0401</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13 14">Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 13 14">
            <text>ATP + D-glutamate + UDP-N-acetyl-alpha-D-muramoyl-L-alanine = ADP + H(+) + phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate</text>
            <dbReference type="Rhea" id="RHEA:16429"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29986"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83898"/>
            <dbReference type="ChEBI" id="CHEBI:83900"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.9"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 13 14">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 13 14">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 13">Belongs to the MurCDEF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.9" evidence="5 13 14"/>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95206">
        <property type="protein sequence ID" value="PRC95206"/>
        <property type="gene ID" value="S2091_0401"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004326">
        <property type="term" value="F:tetrahydrofolylpolyglutamate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008764">
        <property type="term" value="F:UDP-N-acetylmuramoylalanine-D-glutamate ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00639">
        <property type="entry name" value="MurD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018109">
        <property type="entry name" value="Folylpolyglutamate_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036565">
        <property type="entry name" value="Mur-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004101">
        <property type="entry name" value="Mur_ligase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036615">
        <property type="entry name" value="Mur_ligase_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013221">
        <property type="entry name" value="Mur_ligase_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005762">
        <property type="entry name" value="MurD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02875">
        <property type="entry name" value="Mur_ligase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08245">
        <property type="entry name" value="Mur_ligase_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53244">
        <property type="entry name" value="SSF53244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53623">
        <property type="entry name" value="SSF53623"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01087">
        <property type="entry name" value="murD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01011">
        <property type="entry name" value="FOLYLPOLYGLU_SYNT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11 13 14" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="8 13 14" id="KW-0132">Cell division</keyword>
    <keyword evidence="9 13 14" id="KW-0133">Cell shape</keyword>
    <keyword evidence="12 13 14" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="7 13" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="13 17" id="KW-0436">Ligase</keyword>
    <keyword evidence="13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10 13 14" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mur_ligase_M" evidence="16">
        <location>
            <begin position="124"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="domain" description="Mur_ligase_C" evidence="15">
        <location>
            <begin position="349"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="126"/>
            <end position="132"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00015655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00639"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU003664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF02875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF08245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="PRC95206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="498" mass="53409" checksum="2124EB6C299BC744" modified="2018-07-18" version="1">MSYSNKKVLVLGLGESGLAAAHWLVRCGAVLRVADTREAPERLAQLMDIAPQCEFISGKFSPALLDDIDFIVASPGLSENNELAEIAPIAAQRAIPVWSEIEIFAQSLLHLREAQNYQPKVLAITGTNGKTTVTSLVGLLVERAGKSVRIAGNISPAVLDVLRIALDENRLPEVWVLELSSFQLHSTYSLQADAATVLNLTQDHLDWHGSMEAYAADKARIFSEHTVQVLNRDDSAVMGMQTLATEQFTFGQSAPKRPGEFGLHSEHGMNWLCVANAVEDEAAPTKRKLKNQIAVEVEVHVARLMPADALKIRGNHNATNALAALALCRAIDLPLAPLLHGLREYQGEPHRVELIATIDQVDYYDDSKGTNVGATVAAINGLASAHSKILLIAGGAGKGQNFTPLHDPVAKSVAAVFLIGEASDEIALALDSSGAELVRCASMEQAVSEAAAMARSGDMVLLSPACASFDMFKNYAHRAQVFIDAVKEVGYTRGEVGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSC5</accession>
    <name>A0A2S9GSC5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4678</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000044">
        <property type="protein sequence ID" value="PRC90610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90610">
        <property type="protein sequence ID" value="PRC90610"/>
        <property type="gene ID" value="S2091_4678"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC90610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="159" mass="18626" checksum="A809F8CB12DC577B" modified="2018-07-18" version="1">MMDQLFDEIFNLFNNLPYPDDDNISDKNSIEASYVSNYFRGKQWDKLGVKELQEDYPGDPSACLSFMTPSAFRYFFPGYMKMALIEYDIADAIFDVVINKLVTTATDPNYYYRSIFEAYDHIYLNAIAKYLVVMSDKYCKHYPVDEAALALKSYWSKYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSE6</accession>
    <name>A0A2S9GSE6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ATPases involved in chromosome partitioning</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_4645</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000041">
        <property type="protein sequence ID" value="PRC90637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90637">
        <property type="protein sequence ID" value="PRC90637"/>
        <property type="gene ID" value="S2091_4645"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025669">
        <property type="entry name" value="AAA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13614">
        <property type="entry name" value="AAA_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_31" evidence="2">
        <location>
            <begin position="3"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="91"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC90637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="258" mass="28252" checksum="07A0D701412D7B7B" modified="2018-07-18" version="1">MAKIFCIANQKGGVGKTTTTVNLAASLAQINQRVLLVDLDPQGNATMGSGVNKSKLSATIYQVLLGLSDVKTVRQRAACETYDVLPANRELAGAEVEMVELENRENRLRLALAEVVGEYDFILIDCPPALSMLTLNGLCAAHGVIIPMQCEYYALEGLSDLANTIKKVHLNLNRELEIIGLLRVMFDPRMTLSQQVSDQLEQHFGDKVFKTLIPRNVRLAEAPSYGMPGVIFDPTSKGALAYLAFAAEMVERIKQLSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSJ5</accession>
    <name>A0A2S9GSJ5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative lipoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_4580</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000038">
        <property type="protein sequence ID" value="PRC90687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90687">
        <property type="protein sequence ID" value="PRC90687"/>
        <property type="gene ID" value="S2091_4580"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042268">
        <property type="entry name" value="BamC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010653">
        <property type="entry name" value="NlpB/DapX"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06804">
        <property type="entry name" value="Lipoprotein_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015690172" evidence="2">
        <location>
            <begin position="26"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="50"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="63"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC90687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="388" mass="43030" checksum="F4E5A42029EB08BE" modified="2018-07-18" version="1">MTMRNNSRNNSLSKMVSMLAVVAIAGCSSTGNFLQPDRIDYKSASKKDAVAPTLDVPPDLSQISRDNRFSIPDNGSTGPLTASSFNAKSSGAATQQTVAAPVTTAINTLEDMRIERDGSQRWLLVKQSPEVLWPKIKDFWQENGFLINQDSQTTGVMETDWAENRAKIPEDFLRKTIGYVFDSLYSTGERDKFRTRLERRDDGSTEIYISHRGVEEVLIGAQKDTTTWAARPNDPALEAAFLTRLMVSLGATQEKAKEIVATTVNQPIKAKLVKDGAASLINVDESFDRAWRRVGLALDRVGFTVEDRDRAKGIYFVRYVDPDGDSNKDGFFSRIFSFGDKEKDAKRYRITVKGEANVTHVAVQNNDGGAENSAASDKILNLLLEQLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSJ8</accession>
    <name>A0A2S9GSJ8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">TPR repeat</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_4630</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000039">
        <property type="protein sequence ID" value="PRC90680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90680">
        <property type="protein sequence ID" value="PRC90680"/>
        <property type="gene ID" value="S2091_4630"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001440">
        <property type="entry name" value="TPR_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00515">
        <property type="entry name" value="TPR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="14"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="48"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="82"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="116"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="150"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="184"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="218"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="252"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="286"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="320"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="354"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="388"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="422"/>
            <end position="455"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC90680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="765" mass="85121" checksum="F59E6F5279D76B85" modified="2018-07-18" version="1">MSTKKTSNSLVEQVQAKLQQALSHHQHGQLAIAEALYLDILKTQPKQIDCLHLLGVIASQSMQHQKAVDLISQAIALSPNNPHFYSNRGLALKELNQLDAAIANYDRAIALSPDFAEAHSNRAVALTELNRLDEAVASNNRAIAINPQSAVVHYNQGVALFGLNQLEAALASYDRAIRIKPDYAEAYSSRGTTLKNLKQAEAAVASYDQAIAINPNDAETYACRAMAFTELNQADAAIASYNRAIELNPKHAVAYLNLGIIQEIQLKHAEAIANFDRAIAINPNFADAYANRGIALKECNQCAAAIASYDQAIAIKPDFAEVHSNRGIAFYALKQYDAAIASYDRAIALKPDFADAYSNRGVAYKELKLLESAAASFERAYTINPDYAAAYSNHGIIFHELKMLKEAIADYDCAISIDPNYAHAYSNRGVVYQELNQLEKAIFDYNRAITIDPNYTDAYLNKAFTLLLSGDFEQGWSLYEWRLKERETELRERYAPHPTWSGKESLKGKTIVLHSEQGFGDTIQFCRYVKLVAHLGAQVIVEVEKPLINLFSTLEGVDKIIVKGTELPSYDFHCPMMSLPLAFKTNSETIPSAPNYLSTDQAKIAYWTQKLGEKTTLRVGLVWSGNPDYKNDRSRSISLSTLLAQLSPDYQYVSLQKDIRDGDDAIIKSHKNFIHTGDEITDFSDTAALCELMDVIVSVDTSTAHLSGALGKPTWLLLPFNPDFRWLLNRDDSPWYPSVKLYRQKNAGDWNEVLETIKNDLTRLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSP0</accession>
    <name>A0A2S9GSP0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4568</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000037">
        <property type="protein sequence ID" value="PRC90742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90742">
        <property type="protein sequence ID" value="PRC90742"/>
        <property type="gene ID" value="S2091_4568"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021393">
        <property type="entry name" value="DUF3034"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11231">
        <property type="entry name" value="DUF3034"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015547533" evidence="1">
        <location>
            <begin position="28"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="307" mass="32743" checksum="B264E57542DC6431" modified="2018-07-18" version="1">MKLNHFNSLTLMAAMIGLTLNSSGAFADDTNKPAYIPDMGKLLATGGISTVEGAAGGGITPWALIGGYGTRDSYGANAHYTYLGTQDFALDTFGATVGIMDRIELSVARQNFKSNNGPLNGLNIQQDIFGVKVKIAGDAVYDQDSCMPQIAVGAEYKKNNGLTGIMNAPVTALGAQKTSGTDYYVSATKLFLDQSILADVTIRATEANQMGLLGFGGDLNDSYKAEFEGSLGYLFTKNWVAGVEYREKPHNLKADNEAAYYDAFVAWFPTKTVSFTLAYANLGSIVAPVTMNNQSQKGLYLSLQAGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSY6</accession>
    <name>A0A2S9GSY6_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Biotin--[biotin carboxyl-carrier protein] ligase</fullName>
            <ecNumber evidence="3">6.3.4.15</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_4469</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + biotin + L-lysyl-[protein] = AMP + diphosphate + H(+) + N(6)-biotinyl-L-lysyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:11756"/>
            <dbReference type="Rhea" id="RHEA-COMP:9752"/>
            <dbReference type="Rhea" id="RHEA-COMP:10505"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57586"/>
            <dbReference type="ChEBI" id="CHEBI:83144"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.4.15"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.15" evidence="3"/>
    <dbReference type="EMBL" id="PUGF01000035">
        <property type="protein sequence ID" value="PRC90806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90806">
        <property type="protein sequence ID" value="PRC90806"/>
        <property type="gene ID" value="S2091_4469"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004077">
        <property type="term" value="F:biotin-[acetyl-CoA-carboxylase] ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd16442">
        <property type="entry name" value="BPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004408">
        <property type="entry name" value="Biotin_CoA_COase_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003142">
        <property type="entry name" value="BPL_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004143">
        <property type="entry name" value="BPL_LPL_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008988">
        <property type="entry name" value="Transcriptional_repressor_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02237">
        <property type="entry name" value="BPL_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03099">
        <property type="entry name" value="BPL_LplA_LipB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50037">
        <property type="entry name" value="SSF50037"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00121">
        <property type="entry name" value="birA_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51733">
        <property type="entry name" value="BPL_LPL_CATALYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0092">Biotin</keyword>
    <keyword evidence="5" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BPL/LPL catalytic" evidence="4">
        <location>
            <begin position="15"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC90806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="266" mass="28105" checksum="017E41354A348972" modified="2018-07-18" version="1">MRAMTTHTPSLVVEKIAAHCSALAQSVAIEVVAQTGSTNADLLARLPTFSSPLVLVAETQTAGRGRAGRSWLSAPGSSLTFSLAWPFSQSPQALLGLPLAVGVALADALGSLDVTVRLKWPNDILKDGKKLAGVLIETANHSNQTWAVIGVGLNLLMPEELEQQIGRPVADATWLAQMDRNQLLAILINHLVVCLQQFSNSGFSAFVPSWNAFHAYAGQHVSILDQGQITQQGVALGVDASGCLLLQDQRGVVCSIMAGDVSLRPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GT08</accession>
    <name>A0A2S9GT08_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phage integrase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_4435</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000034">
        <property type="protein sequence ID" value="PRC90854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90854">
        <property type="protein sequence ID" value="PRC90854"/>
        <property type="gene ID" value="S2091_4435"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002104">
        <property type="entry name" value="Integrase_catalytic"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00589">
        <property type="entry name" value="Phage_integrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51898">
        <property type="entry name" value="TYR_RECOMBINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyr recombinase" evidence="2">
        <location>
            <begin position="165"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC90854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="341" mass="39035" checksum="A52519507605D138" modified="2018-07-18" version="1">MASIRQKNGAWVVDIRRKGHKSISKSFRTKSLAQTWAREIEQQIDSMQYKDVRSLALVTVRALIDKYIEEIGSIKKIGRTKADSLRKWKITHGALTVSELTDDLLIKHIQQRAKTVSGVTIAVDLAYLSGVLKTAKELWRMPVDMSVTVTARASLRYLGLTSKSRERDRRPTNGEIEDICLHFAIKTRQRVPMGDLIHFAIETAMRAGEIVNLRWQDINHDHKTITIRNRKHPTEKEGNHQEVPLLGTAYDILVRQPKKDKEERIFPIAEGTVSSLFPRACNALGIDDLRFHDLRHEGVSRLFERGLSIMEVSLISGHRDLKMLKRYVNLRAVDISNKYLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GT57</accession>
    <name>A0A2S9GT57_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4397</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000033">
        <property type="protein sequence ID" value="PRC90904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90904">
        <property type="protein sequence ID" value="PRC90904"/>
        <property type="gene ID" value="S2091_4397"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="82"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="100"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="142" mass="16031" checksum="D9B026B0586F9EF6" modified="2018-07-18" version="1">MTNLRLGAGGRPCIPIGRESPPACGDRSAGEWHATQNPCYTGNYSLFFSPKKVSKKRRPRYFGNPDFSKEKREKFETRCAQTTNLSDPFSLRKTGRTRSGGRSKSTTTSKPTSTATQPNFNQHRQFPLTLHNNISIQLYLFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GT70</accession>
    <name>A0A2S9GT70_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Putative metalloendopeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">S2091_4412</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000033">
        <property type="protein sequence ID" value="PRC90919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90919">
        <property type="protein sequence ID" value="PRC90919"/>
        <property type="gene ID" value="S2091_4412"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08662">
        <property type="entry name" value="M13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1380.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000718">
        <property type="entry name" value="Peptidase_M13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018497">
        <property type="entry name" value="Peptidase_M13_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042089">
        <property type="entry name" value="Peptidase_M13_dom_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008753">
        <property type="entry name" value="Peptidase_M13_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11733">
        <property type="entry name" value="PTHR11733"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01431">
        <property type="entry name" value="Peptidase_M13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05649">
        <property type="entry name" value="Peptidase_M13_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00786">
        <property type="entry name" value="NEPRILYSIN"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51885">
        <property type="entry name" value="NEPRILYSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015448929" evidence="8">
        <location>
            <begin position="34"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M13_N" evidence="10">
        <location>
            <begin position="60"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M13" evidence="9">
        <location>
            <begin position="497"/>
            <end position="695"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF05649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC90919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="698" mass="76665" checksum="9CDF87B6C289239E" modified="2018-07-18" version="1">MKPSSLVHKFTLKPLALTCLALCFAGATLPAYSSEYATDSAASKPSTTFTIDGMNTGVKPGDDFNAYANGGWEKTAVIPADQSSWGIFGEINERTNKQLSALIQAATQAAPGSEERKVGDFYTAFMDTATIEKTGIAPLKARLDSISALKNKADLSTYLGANLKADVDPINATSVWTENLFGMWISQGFHDNTTYTAYLLQGGLGLPDREYYLTKNPKMVELRAKYRAYVAAMLKLAGIANPEQAAIRVVNLEQKIAITHAPREDTSNVLKADNTWAKADFSRKAAGMDWANYFAAAGLTEQASFIIWHPSAVKGEAALVASVSLADWQDYLRFHAINSHASVLPKAFSDQKFAFYGTTMSGTPEQQERSIRAIEMANGSLGDALGKLYVAKHFSPEAKAKVRALVSNLLDAFSQRITTLDWMAPSTKAEAQAKLKSMYVGVGYPDTWRDFSGLEIRADDAFGNLERAQAYTYQQALAKLGKPVDVAQWCMVAQEINAVNMPMQNAINFPAAILQAPYFDINASDAANYGSIGATIGHEISHSFDDSGAQFDSKGELRNWWQKSDFSHFKKSAKALAAQYSAYRPFPDLAINGQQTLSENIADLAGLNVAYDAFHKASGKQDAATDKRLDQEFFLSYAESWRGVEREQALRRQITTNEHAPDSFRVFTVRNLDAWYGAFDVQAGEKLYLAPKDRVRVW</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTL5</accession>
    <name>A0A2S9GTL5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Sigma 54 modulation protein / S30EA ribosomal protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4241</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000030">
        <property type="protein sequence ID" value="PRC91053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91053">
        <property type="protein sequence ID" value="PRC91053"/>
        <property type="gene ID" value="S2091_4241"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044238">
        <property type="term" value="P:primary metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036567">
        <property type="entry name" value="RHF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003489">
        <property type="entry name" value="RHF/RaiA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02482">
        <property type="entry name" value="Ribosomal_S30AE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69754">
        <property type="entry name" value="SSF69754"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="1" id="KW-0810">Translation regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="120" mass="13336" checksum="F050F1B9BC7254F3" modified="2018-07-18" version="1">MHIQLNTDNTVESHAPLVAHVETIVAETLQRFSERISRVEIHLSLINDHKHSGGEHKCVMEARIEGHPPIIASDHAISMHHSIHGAVNKLRRAIESTFGRINVNNKNGDAVNDTDPQFSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTN2</accession>
    <name>A0A2S9GTN2_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Selenide, water dikinase</fullName>
            <ecNumber evidence="5">2.7.9.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Selenium donor protein</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Selenophosphate synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">selD</name>
        <name evidence="8" type="ORF">S2091_4178</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Synthesizes selenophosphate from selenide and ATP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>ATP + H2O + hydrogenselenide = AMP + 2 H(+) + phosphate + selenophosphate</text>
            <dbReference type="Rhea" id="RHEA:18737"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16144"/>
            <dbReference type="ChEBI" id="CHEBI:29317"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.7.9.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="5">Binds 1 Mg(2+) ion per monomer.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the selenophosphate synthase 1 family. Class I subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.9.3" evidence="5"/>
    <dbReference type="EMBL" id="PUGF01000029">
        <property type="protein sequence ID" value="PRC91082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91082">
        <property type="protein sequence ID" value="PRC91082"/>
        <property type="gene ID" value="S2091_4178"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004756">
        <property type="term" value="F:selenide, water dikinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016260">
        <property type="term" value="P:selenocysteine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02195">
        <property type="entry name" value="SelD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.650.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00625">
        <property type="entry name" value="SelD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010918">
        <property type="entry name" value="PurM-like_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036676">
        <property type="entry name" value="PurM-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016188">
        <property type="entry name" value="PurM-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036921">
        <property type="entry name" value="PurM-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023061">
        <property type="entry name" value="SelD_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004536">
        <property type="entry name" value="SPS/SelD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10256">
        <property type="entry name" value="PTHR10256"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00586">
        <property type="entry name" value="AIRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02769">
        <property type="entry name" value="AIRS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036407">
        <property type="entry name" value="Selenphspht_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55326">
        <property type="entry name" value="SSF55326"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56042">
        <property type="entry name" value="SSF56042"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00476">
        <property type="entry name" value="selD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 5 8" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0711">Selenium</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AIRS" evidence="6">
        <location>
            <begin position="50"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="domain" description="AIRS_C" evidence="7">
        <location>
            <begin position="169"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="17"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="20"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="48"/>
            <end position="50"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="51"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="68"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="91"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="139"/>
            <end position="141"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="227"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="5">
        <location>
            <position position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00625"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC91082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="353" mass="36373" checksum="2EA12272F21E100D" modified="2018-07-18" version="1">MTTTPIKLTSFSHGGGCGCKIAPGVLAEILKNSNGFPIPPQLMVGIENSDDAAVYKLNEEQALIATTDFFMPIVDDPFDFGRIAATNAISDVYAMGGTPIMALALVGMPINKLPLDVITNIIKGGETICAEAGIPIAGGHTIDSVEPIYGLVVLGLVHPSKVKRNGDAKAGDQLILGKGLGVGILSAALKKGLLDEAGYTCMINTTTQLNKPGAALSNMDGVGAVTDVTGFGLLGHLLEVARAAKLTANLSMQSIPLLDNVMTLAEQGCITGASGRNWAAYGHEVSLLDGVSQIHQHLLSDPQTSGGLLVSVRPEAVASVLALFHAQGFPHACVIGELVEKPVTSAANIIVAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTR2</accession>
    <name>A0A2S9GTR2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4187</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000029">
        <property type="protein sequence ID" value="PRC91091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91091">
        <property type="protein sequence ID" value="PRC91091"/>
        <property type="gene ID" value="S2091_4187"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041492">
        <property type="entry name" value="HAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13419">
        <property type="entry name" value="HAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00413">
        <property type="entry name" value="HADHALOGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01549">
        <property type="entry name" value="HAD-SF-IA-v1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01509">
        <property type="entry name" value="HAD-SF-IA-v3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="244" mass="27304" checksum="6E98E7555C59FCE0" modified="2018-07-18" version="1">MRHKNSRKPQNLSIKAVIFDLDDTLWPIIPLINHAEQTLFDWLQANAPKVTEQHSIQSMRNFRAALIPTNPRYQFDLWALRHAMLTQLFLSTGEDANTVNNKADTAMQVFAAARNQVSLYDDVIPTLTELGRHFQLGSISNGFADLEQIGLAEHFKVSIAAHQFGCAKPDPSIFKAACAALNVEPQHAVYVGDDVLLDVRGAQDAGLASVWINRTKRPGWSEVRADYECRDLTELLAWLLNGRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTR3</accession>
    <name>A0A2S9GTR3_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Aspartate carbamoyltransferase</fullName>
            <ecNumber evidence="8">2.1.3.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Aspartate transcarbamylase</fullName>
            <shortName evidence="8">ATCase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">pyrB</name>
        <name evidence="12" type="ORF">S2091_4206</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2 8">
            <text>carbamoyl phosphate + L-aspartate = H(+) + N-carbamoyl-L-aspartate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20013"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:32814"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58228"/>
            <dbReference type="EC" id="2.1.3.2"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>carbamoyl phosphate + L-ornithine = H(+) + L-citrulline + phosphate</text>
            <dbReference type="Rhea" id="RHEA:19513"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:46911"/>
            <dbReference type="ChEBI" id="CHEBI:57743"/>
            <dbReference type="ChEBI" id="CHEBI:58228"/>
            <dbReference type="EC" id="2.1.3.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 8">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 2/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 8">Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.3.2" evidence="8"/>
    <dbReference type="EMBL" id="PUGF01000029">
        <property type="protein sequence ID" value="PRC91110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91110">
        <property type="protein sequence ID" value="PRC91110"/>
        <property type="gene ID" value="S2091_4206"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00070">
        <property type="reaction ID" value="UER00116"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016597">
        <property type="term" value="F:amino acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004070">
        <property type="term" value="F:aspartate carbamoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004585">
        <property type="term" value="F:ornithine carbamoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006207">
        <property type="term" value="P:'de novo' pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044205">
        <property type="term" value="P:'de novo' UMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1370">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00001">
        <property type="entry name" value="Asp_carb_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006132">
        <property type="entry name" value="Asp/Orn_carbamoyltranf_P-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006130">
        <property type="entry name" value="Asp/Orn_carbamoylTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036901">
        <property type="entry name" value="Asp/Orn_carbamoylTrfase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002082">
        <property type="entry name" value="Asp_carbamoyltransf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006131">
        <property type="entry name" value="Asp_carbamoyltransf_Asp/Orn-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11405:SF16">
        <property type="entry name" value="PTHR11405:SF16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00185">
        <property type="entry name" value="OTCace"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02729">
        <property type="entry name" value="OTCace_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00100">
        <property type="entry name" value="AOTCASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53671">
        <property type="entry name" value="SSF53671"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00670">
        <property type="entry name" value="asp_carb_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00097">
        <property type="entry name" value="CARBAMOYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="OTCace_N" evidence="11">
        <location>
            <begin position="13"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="domain" description="OTCace" evidence="10">
        <location>
            <begin position="170"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00008896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PRC91110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="319" mass="34956" checksum="2DD98C6050C67B74" modified="2018-07-18" version="1">MHNPQLNQHGELQHLLTTEGLPKSVIHHILDTAESFVSIGNREVKKVPLMRGKSVFNLFFENSTRTRTTFEIASKRLSADVINLNIAASSTSKGESLLDTIDNLAAMHADMFVVRHAQSGAPYLIAKHLRDTNQNHVHVVNAGDGRHAHPTQGLLDMYTIRHYKKDFTQLRVAIVGDILHSRVARSDIHALTTLGVPEVRAIGPRTLLPGGLEQMGVRVFTDMNEGLKDVDVIITLRLQNERMSGALLPSAQEFFKSYGLTPERLALAKPDAIVMHPGPMNRGVEIDSAVADGPQAVILPQVTFGIAVRMAVMSILAGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTV6</accession>
    <name>A0A2S9GTV6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4141</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000028">
        <property type="protein sequence ID" value="PRC91140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91140">
        <property type="protein sequence ID" value="PRC91140"/>
        <property type="gene ID" value="S2091_4141"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="5"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="28"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="56"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="89" mass="9948" checksum="2883917B1F4A108A" modified="2018-07-18" version="1">MYFLLKIACIVIYLGAALSLVVDLPHGLALACQSITVLFLVAHVIEVMIFMPHLRLYKGPLSTSILLTLIFGLFHWKPLLDASKRDVKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTW3</accession>
    <name>A0A2S9GTW3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4149</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000028">
        <property type="protein sequence ID" value="PRC91148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91148">
        <property type="protein sequence ID" value="PRC91148"/>
        <property type="gene ID" value="S2091_4149"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010752">
        <property type="entry name" value="DUF1329"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07044">
        <property type="entry name" value="DUF1329"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015708897" evidence="1">
        <location>
            <begin position="30"/>
            <end position="454"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="454" mass="50655" checksum="8492F8795991345F" modified="2018-07-18" version="1">MKKNQTTSKALVTLAVLACFCSASFNALAGMAAADADRLGKDLTPMGSEKAGNSNGSIPVWDGGIAKAPAGFDAKAGYLDPFANEKPLFTVTGANMQQYKDKLAPGQMEMLKRFPDYKINVYPSHRTTAYPQNVYDSIKTEATKIELAEGGNGIKNVTHSTVPFPAPKSGIEVIWNHLLRYRGGSIQRFSTEFPVQANGAFTPVTRSETLVLAQAMTNPEPNRLLYFMGSITGPSSVAGESLLVIDPMDQVKESRQAWVYNPGQRRVLRAPDISYDSPGTGADGLRTTDDYDGYNGSPDRYDWKLIGKKEMFISYNNYKLTSKNVKYVDIIRPGHTNQEMVRYEPHRVWVVEATLKNGMRHIYAKRTFYIDEDSWQIAHADAYDGRGELWRVHELAAVQYYDAPAPWFACETIYDLQARRYLVTGLSNQEKPIKFGANIQASYFTADNLRRISN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTY2</accession>
    <name>A0A2S9GTY2_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CYTH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_4090</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000027">
        <property type="protein sequence ID" value="PRC91195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91195">
        <property type="protein sequence ID" value="PRC91195"/>
        <property type="gene ID" value="S2091_4090"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033469">
        <property type="entry name" value="CYTH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023577">
        <property type="entry name" value="CYTH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012042">
        <property type="entry name" value="NeuTTM/CthTTM-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40114">
        <property type="entry name" value="PTHR40114"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01928">
        <property type="entry name" value="CYTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016487">
        <property type="entry name" value="CYTH_UCP016487"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01118">
        <property type="entry name" value="CYTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55154">
        <property type="entry name" value="SSF55154"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51707">
        <property type="entry name" value="CYTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CYTH" evidence="2">
        <location>
            <begin position="2"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR016487-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="153" mass="17529" checksum="D6AFF52AD42C2C9D" modified="2018-07-18" version="1">MALEIERKFLVLGSPWQDLPRSAVMRQGYLLASPERVVRVRIEGADAMLTIKGAMQGIVRSEWEYPIPLADADELLKLCEQPLIEKYRYRIPHDGMLWELDVFIGDNAGLVVAEIELESEGQTFSKPAWVGEEVTDDKRYLNANLLRHPFSTW</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GU51</accession>
    <name>A0A2S9GU51_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Tryptophan--tRNA ligase</fullName>
            <ecNumber evidence="2">6.1.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_4050</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.2" evidence="2"/>
    <dbReference type="EMBL" id="PUGF01000026">
        <property type="protein sequence ID" value="PRC91265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91265">
        <property type="protein sequence ID" value="PRC91265"/>
        <property type="gene ID" value="S2091_4050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004830">
        <property type="term" value="F:tryptophan-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006436">
        <property type="term" value="P:tryptophanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00806">
        <property type="entry name" value="TrpRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002305">
        <property type="entry name" value="aa-tRNA-synth_Ic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002306">
        <property type="entry name" value="Trp-tRNA-ligase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00579">
        <property type="entry name" value="tRNA-synt_1b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01039">
        <property type="entry name" value="TRNASYNTHTRP"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00233">
        <property type="entry name" value="trpS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 8 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC91265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="338" mass="37735" checksum="0B3E4B978BC93252" modified="2018-07-18" version="1">MHTTDNKQHLILTGDRPTGPLHLGHYVGSLCNRVKFQHQYQQFIMLADAQALTDNMDDPGKVHRNVLEVALDYLAVGIDPTLSTIFIQSQIPELTELTFYYLNLVTVARLERNPTIKEEIRLRNFERDIPAGFLTYPVSQAADISAFKATLVPVGEDQIPMIEQTNEIVRRFNRLVNQEILVECQALVPEIGRLPGIDGKAKMSKSLGNVINLGATAAEIRAAVKKTYTDPLHLRIEDPGHLEGNVAFTYLDAFDNDKTSLAEMKAHYVRGGLGDGTVKKRLEECLQELIGPIRERRAALAEDRGYVLQILKQGTEKAREVAAKTTDEVKAALGLKHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GU84</accession>
    <name>A0A2S9GU84_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative enzyme of heme biosynthesis</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4054</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000026">
        <property type="protein sequence ID" value="PRC91269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91269">
        <property type="protein sequence ID" value="PRC91269"/>
        <property type="gene ID" value="S2091_4054"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007470">
        <property type="entry name" value="HemX"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38043">
        <property type="entry name" value="PTHR38043"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04375">
        <property type="entry name" value="HemX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="240"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="397" mass="43978" checksum="F2C123B8BDD2D54F" modified="2018-07-18" version="1">MNESLNPTPPNPAQQSTNSTSTELVPAAVNSDQTVEKSPRAQVLKPSHLTYAALAGLTVLLVAQWWSSTNQISQLREELARRLQTADVGNAETKIIAKSMQETGKELQVKIGVLESKQAESESHALALQQLYQDLSKNRDDWALSEIEQVLSTASQQLQLAGNVQGALIALQNADARLARSDKPQFITIRRSISHDIDRLKALPNLDLPGIALRLDSAIAQIENMPLWVDENPVIVTSPVKGREPAKNAGNAANSKAAKESHQAEVGNAAGWMLWLDDRWQSWSTEMWDQLRQLVRIRNVENPDALLLAPSQGYFAKENVKLRLLNARLALLSRSETPFRSDMIAAQDEIARYFDTRAKQTQTVQALLRQIQSSNVSIEMPSLAESLNAVRNFTVKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GU87</accession>
    <name>A0A2S9GU87_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3968</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000025">
        <property type="protein sequence ID" value="PRC91297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91297">
        <property type="protein sequence ID" value="PRC91297"/>
        <property type="gene ID" value="S2091_3968"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015704240" evidence="1">
        <location>
            <begin position="23"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="141" mass="14863" checksum="B98C3B111A43F07A" modified="2018-07-18" version="1">MNNLIKAMFFCAALICMQSAFCQIAVVVGAKSDISTLTTDQVSSVFLGKSDKFPNGNTALPLDQASGSAIRGTFYDKVTGKSEAQVKSAWSRLVFSGKGTPPKEVSSSAEVKKLVSSNPNTIGYIEKSAVDSSVKVVLTSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUK2</accession>
    <name>A0A2S9GUK2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Mycolic acid cyclopropane synthetase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3830</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CFA/CMAS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000023">
        <property type="protein sequence ID" value="PRC91415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91415">
        <property type="protein sequence ID" value="PRC91415"/>
        <property type="gene ID" value="S2091_3830"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008610">
        <property type="term" value="P:lipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003333">
        <property type="entry name" value="Mycolic_cyclopropane_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003085">
        <property type="entry name" value="CMAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" evidence="2">
        <location>
            <position position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR003085-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="412" mass="46309" checksum="15D631D2ADD097C0" modified="2018-07-18" version="1">MFWEKKLEQWAANIRDQLALPLRVDLWNGQQLSLSHTEPQVIVRVPHVSALSCLFTPSLSNLGAAYVDGKIDVEGTPSAIISIGNALASGTLKLEGKFSRIARKIQRSKEKDRQAIQYHYDVSDEFYKLWLDENMVYSCAYFENGDEDLISAQIKKMDLILQKIQLRPGDTLLDIGCGWGALVIHAAKHYGARCVGITLSENQADYAKALVIKLGLCDLIEIRLQDYRDVDGTFDRITSVGMFEHVGIRNLPSYFSKINSLLAVDGIVMNHGITSTDADSGETPYGNGEFIEKYVFPHGELPHIGLALKTMQEGGLEAIDIENLRRHYAKTCELWGDQFEANSEEIKRLSGDRRYRIWRVYLAGCAYAFNQDWISLYQVVCVKAGRNPSTLPLPSRHLYGRAELRTGTNMIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUQ9</accession>
    <name>A0A2S9GUQ9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Carbonic anhydrases/acetyltransferases isoleucine patch superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3750</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000022">
        <property type="protein sequence ID" value="PRC91472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91472">
        <property type="protein sequence ID" value="PRC91472"/>
        <property type="gene ID" value="S2091_3750"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="174" mass="18727" checksum="602A8693C40C19EF" modified="2018-07-18" version="1">MTIYQLSDSIPQIDDSAFVADSANVIGKVHIAAHASVWFEVTIRGDNELISVGENSNVQENVVLHTDIGYPLTIGRNVTVGHQAMLHGCTIQDGALIGIQAVILNGAVIGKNCLVGAGALVTEGKHFPDNSLIIGSPAKVARTLTEEEINNFHKNTDNYVTRAQLFKTKLIRLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUR0</accession>
    <name>A0A2S9GUR0_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Common pilus major fimbrillin subunit EcpA</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">MatB fimbrillin</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_3864</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="5">Self-associates. Forms filaments. Interacts with EcpD.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Fimbrium</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the EcpA/MatB fimbrillin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000023">
        <property type="protein sequence ID" value="PRC91449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91449">
        <property type="protein sequence ID" value="PRC91449"/>
        <property type="gene ID" value="S2091_3864"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009289">
        <property type="term" value="C:pilus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.3290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016514">
        <property type="entry name" value="EcpA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038478">
        <property type="entry name" value="Fimbrillin_EcpA_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16449">
        <property type="entry name" value="MatB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0281">Fimbrium</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015473606" description="Common pilus major fimbrillin subunit EcpA" evidence="7">
        <location>
            <begin position="24"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00014507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00026091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00031192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC91449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="215" mass="22438" checksum="30B78780C8B89FBD" modified="2018-07-18" version="1">MNAALNKSMLVSIFASVAFPVLAATTTVSSSVTWKAEAIKKTDVELNVFASNDSLQFKWDPTNKRFSTASSSLTVQAAGKVGTTSYQITSQLTRNKLTHVSGAAIGTVSISSAVGGIAMDVAPVSILEGDRTKGVTLAASGMNGMNLEFEGPNAATNGTYHEAERVKVDFNILSGTDSKNSPLSRGSAEAGLDKLADGTYEGVVEMNFVASWTKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUU4</accession>
    <name>A0A2S9GUU4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NAD dependent epimerase/dehydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3761</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000022">
        <property type="protein sequence ID" value="PRC91483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91483">
        <property type="protein sequence ID" value="PRC91483"/>
        <property type="gene ID" value="S2091_3761"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016831">
        <property type="term" value="F:carboxy-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05257">
        <property type="entry name" value="Arna_like_SDR_e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045869">
        <property type="entry name" value="Arna-like_SDR_e"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026390">
        <property type="entry name" value="EDH_00030"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16363">
        <property type="entry name" value="GDP_Man_Dehyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04180">
        <property type="entry name" value="EDH_00030"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-bd_dom" evidence="1">
        <location>
            <begin position="5"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF16363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="332" mass="36143" checksum="3532CEB756B85523" modified="2018-07-18" version="1">MTKLLITGADGFIGSHLTEALVRAGHDVRAFVLYNSFNSWGWLDRCDADVKGKFEVFAGDIRDPHGVRTAMQGCDSVLHLAALIAIPYSYHSPATYIDTNITGTLNVVQAARDLGISKVIHTSTSEVYGTAQFVPITEQHPLEGQSPYSASKIGADQLAMSFYRSFGTPVSIVRPFNTYGPRQSARAVIPTIIIQIANGQRKIKLGAVHPTRDFNYVSDTVNGFIAALNSAQSIGEVINLGSNFEISIGATASTIAEVMGVEIEVISDEQRLRPEKSEVERLWAANDKAQKLLGWSPKYGGLDGLKRGLQETVAWFNDTSNLSAYKADIYNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUY8</accession>
    <name>A0A2S9GUY8_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 10">Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase</fullName>
            <shortName evidence="10">NN:DBI PRT</shortName>
            <ecNumber evidence="4 10">2.4.2.21</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9 10">N(1)-alpha-phosphoribosyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">cobT</name>
        <name evidence="11" type="ORF">S2091_3802</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>5,6-dimethylbenzimidazole + nicotinate beta-D-ribonucleotide = alpha-ribazole 5'-phosphate + H(+) + nicotinate</text>
            <dbReference type="Rhea" id="RHEA:11196"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15890"/>
            <dbReference type="ChEBI" id="CHEBI:32544"/>
            <dbReference type="ChEBI" id="CHEBI:57502"/>
            <dbReference type="ChEBI" id="CHEBI:57918"/>
            <dbReference type="EC" id="2.4.2.21"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 10">Nucleoside biosynthesis; alpha-ribazole biosynthesis; alpha-ribazole from 5,6-dimethylbenzimidazole: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the CobT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.21" evidence="4 10"/>
    <dbReference type="EMBL" id="PUGF01000022">
        <property type="protein sequence ID" value="PRC91524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91524">
        <property type="protein sequence ID" value="PRC91524"/>
        <property type="gene ID" value="S2091_3802"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00061">
        <property type="reaction ID" value="UER00516"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008939">
        <property type="term" value="F:nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009236">
        <property type="term" value="P:cobalamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02439">
        <property type="entry name" value="DMB-PRT_CobT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1610.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10210">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00230">
        <property type="entry name" value="CobT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003200">
        <property type="entry name" value="Nict_dMeBzImd_PRibTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017846">
        <property type="entry name" value="Nict_dMeBzImd_PRibTrfase_bact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023195">
        <property type="entry name" value="Nict_dMeBzImd_PRibTrfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036087">
        <property type="entry name" value="Nict_dMeBzImd_PRibTrfase_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02277">
        <property type="entry name" value="DBI_PRT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52733">
        <property type="entry name" value="SSF52733"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03160">
        <property type="entry name" value="cobT_DBIPRT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0169">Cobalamin biosynthesis</keyword>
    <keyword evidence="7 10 11" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 10 11" id="KW-0808">Transferase</keyword>
    <feature type="active site" description="Proton acceptor" evidence="10">
        <location>
            <position position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00015486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00030686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC91524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="344" mass="36317" checksum="F09DDD598329E693" modified="2018-07-18" version="1">MHISSIESTQDLVLSTLLDVAINNKTKPLGSLGMLEKIAKQIGLIQKSTHPALNDPAILVFAGDHGVVAENISAFPQSVTWQMVENFLAKGAAINVFARQNGFALQIVDAGVNHEFGQRDGLINKKIAPGTRNFAQEPAMSLDQCQQALQSGAALINALKGNVVGFGEMGIGNTTAAAALMHKLTGLPVAKCVGAGTGLAPEGIVHKQRVIEGAVAFHANVVNPLEVLATFGGFEIAMMTGAMLQAAKQRMVLLIDGFICTSALLVAAKLQPEVLDYCVFSHCSDESGHQAMLRYLGAQPLLQLGLRLGEGTGCALAYPLVQASVNFLRDMATFDSAQVSEKKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GV56</accession>
    <name>A0A2S9GV56_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_3723</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine + ATP = 4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + ADP</text>
            <dbReference type="Rhea" id="RHEA:19893"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57841"/>
            <dbReference type="ChEBI" id="CHEBI:58354"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.7"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>4-amino-5-hydroxymethyl-2-methylpyrimidine + ATP = 4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23096"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16892"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58354"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.49"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Cofactor biosynthesis; thiamine diphosphate biosynthesis; 4-amino-2-methyl-5-diphosphomethylpyrimidine from 5-amino-1-(5-phospho-D-ribosyl)imidazole: step 3/3.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000021">
        <property type="protein sequence ID" value="PRC91607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91607">
        <property type="protein sequence ID" value="PRC91607"/>
        <property type="gene ID" value="S2091_3723"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00060">
        <property type="reaction ID" value="UER00138"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008972">
        <property type="term" value="F:phosphomethylpyrimidine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009228">
        <property type="term" value="P:thiamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009229">
        <property type="term" value="P:thiamine diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01169">
        <property type="entry name" value="HMPP_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045029">
        <property type="entry name" value="HMP/HMP-P_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004399">
        <property type="entry name" value="HMP/HMP-P_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013749">
        <property type="entry name" value="PM/HMP-P_kinase-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20858">
        <property type="entry name" value="PTHR20858"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08543">
        <property type="entry name" value="Phos_pyr_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="SSF53613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Phos_pyr_kin" evidence="4">
        <location>
            <begin position="12"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000565"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC91607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="262" mass="27338" checksum="E2D8A18ED02FD159" modified="2018-07-18" version="1">MKPCVLVFAGSDPSGGAGISADIEAIAAQGAHALPIITAITVQDNDRVFAVHPVAADLILQQAQTLTNKMPISAIKIGIIASQTNAAALAGWITAIKKQYPNLPVILDPVLASGHGDALAVEDPLASISPLLNIATLITPNLPEAAKLCPDAKSALQQARHLMQFGATDILIKGGHSTDANITNSWFHGEENRDWQWPRLAGAFHGSGCTLASAIAGQLACGASMQQALEAAQTYCHQTLEHAYAIAPGQLIPNRTFIPNSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVC9</accession>
    <name>A0A2S9GVC9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="8">GtrA-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_3615</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GtrA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000020">
        <property type="protein sequence ID" value="PRC91677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91677">
        <property type="protein sequence ID" value="PRC91677"/>
        <property type="gene ID" value="S2091_3615"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000271">
        <property type="term" value="P:polysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007267">
        <property type="entry name" value="GtrA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04138">
        <property type="entry name" value="GtrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="14"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="38"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="80"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="104"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="domain" description="GtrA" evidence="7">
        <location>
            <begin position="17"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC91677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="135" mass="15324" checksum="720E2D4159D5300D" modified="2018-07-18" version="1">MQFSPKSIALFRQFIHFAAVGLSGTLVQYLSLWIGVEYFLMAAAVASAIGYILGSVVNYLLNYFFTFSSGKSHKEAASKYFSVIGIGWCLNFLLMSLFVKQLGWYYWFAQIITTGIGLLWNFSGSKWWAFKHKPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVF6</accession>
    <name>A0A2S9GVF6_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">30S ribosomal protein S15</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rpsO</name>
        <name evidence="5" type="ORF">S2091_3641</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.</text>
    </comment>
    <comment type="function">
        <text evidence="3">One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the universal ribosomal protein uS15 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000020">
        <property type="protein sequence ID" value="PRC91703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91703">
        <property type="protein sequence ID" value="PRC91703"/>
        <property type="gene ID" value="S2091_3641"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00353">
        <property type="entry name" value="Ribosomal_S15p_S13e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01343_B">
        <property type="entry name" value="Ribosomal_S15_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000589">
        <property type="entry name" value="Ribosomal_S15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005290">
        <property type="entry name" value="Ribosomal_S15_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009068">
        <property type="entry name" value="S15_NS1_RNA-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23321">
        <property type="entry name" value="PTHR23321"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00312">
        <property type="entry name" value="Ribosomal_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01387">
        <property type="entry name" value="Ribosomal_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47060">
        <property type="entry name" value="SSF47060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00952">
        <property type="entry name" value="S15_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1 3 4" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC91703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="89" mass="10020" checksum="D234DF40EA13C346" modified="2018-07-18" version="1">MTIEKQVKAAIVADNARAVNDTGSPEVQVALLTARINDLNGHFKAHSKDHHSRRGLIMMVNRRKSLLSYLKGKDAVRYRDLIVKLGLRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVJ9</accession>
    <name>A0A2S9GVJ9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3486</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000019">
        <property type="protein sequence ID" value="PRC91731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91731">
        <property type="protein sequence ID" value="PRC91731"/>
        <property type="gene ID" value="S2091_3486"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="60" mass="7188" checksum="617F2C0CB2EF6E5F" modified="2018-07-18" version="1">MNLLKSTGRIFLRRCWRQSITHAIPGKFRTLEMFKEWFEVEAAEWVLDLGVYPTREDGEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVV8</accession>
    <name>A0A2S9GVV8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Sigma70-ECF: RNA polymerase sigma factor, sigma-70 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_3413</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000018">
        <property type="protein sequence ID" value="PRC91857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91857">
        <property type="protein sequence ID" value="PRC91857"/>
        <property type="gene ID" value="S2091_3413"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="2">
        <location>
            <begin position="11"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="3">
        <location>
            <begin position="127"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC91857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="189" mass="21594" checksum="E7D689222E3B0CDE" modified="2018-07-18" version="1">MATDKELSDFLESVERRAFKQAVYAVRNEESALDIVQDAMIKLAEKYGDKPAEEIPLLFQRILQNTILDFFRREKVRNTWVSLFSNMSTRKDGNDDFDILENFESEEGSEASESSADKVEREQTLTILDEEIQKLPARQREAFLMRYWEDMDVAETASAMGCSEGSVKTHCSRATHALAKSLKALGIRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVY6</accession>
    <name>A0A2S9GVY6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3414</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000018">
        <property type="protein sequence ID" value="PRC91858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91858">
        <property type="protein sequence ID" value="PRC91858"/>
        <property type="gene ID" value="S2091_3414"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022064">
        <property type="entry name" value="DUF3619"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12279">
        <property type="entry name" value="DUF3619"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="83"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="146" mass="16283" checksum="B3466C89E86068AD" modified="2018-07-18" version="1">MKTTINNSQSSNELEFAYQVRRALDERLAVMPESTANRLSAARKIAIARKKPESAAYAVAPARRFAGNFSHGFSNPFDGSLNWLLRVGIAIPLLILVLGSFGIYQYEQERRINELAELDAAVLTDELPINAFLDHGFDSYLNKHGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVZ7</accession>
    <name>A0A2S9GVZ7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Metallopeptidase family M24</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_3424</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M24B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000018">
        <property type="protein sequence ID" value="PRC91868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91868">
        <property type="protein sequence ID" value="PRC91868"/>
        <property type="gene ID" value="S2091_3424"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0110165">
        <property type="term" value="C:cellular anatomical entity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01085">
        <property type="entry name" value="APP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.350.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029149">
        <property type="entry name" value="Creatin/AminoP/Spt16_NTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000587">
        <property type="entry name" value="Creatinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033740">
        <property type="entry name" value="Pept_M24B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032416">
        <property type="entry name" value="Peptidase_M24_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01321">
        <property type="entry name" value="Creatinase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16188">
        <property type="entry name" value="Peptidase_M24_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53092">
        <property type="entry name" value="SSF53092"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="SSF55920"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Creatinase_N" evidence="3">
        <location>
            <begin position="23"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M24" evidence="2">
        <location>
            <begin position="327"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M24_C" evidence="4">
        <location>
            <begin position="552"/>
            <end position="611"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF16188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC91868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="612" mass="66557" checksum="5C1F6A304B1E5978" modified="2018-07-18" version="1">MPNSSSASAALSSSHSSQIIPQRLALLRQHMASNGIHACLIPSADPHLSEYLPARWQGRAWFSGFTGSVGTLIVTTNFAGLWVDTRYWVQAEQDLIGTGVQMMKIASAGATDHIDWLAANLNADQTVSVDGMILSLAIARQLEQSLSARQIKLNTKLDLLNAAWPDRPSLPTEAVFEHGAPYAVQSRSEKLALVRAAMQELGADAHLISSVDDIAWLLNLRGSDVSYNPVFLAHALINQEHVELFIGKGKIPAELQSALAAQHIHCRDYQQITSALAELPSNSTLLVEPRRVTLGILESCPASVKKIDAINPSTFLKSRKSSAEVQHIRNTMEQDGAALCEFFAWFDNTIGKQVITEMDVDTQICAARAKRPDFVSPSFGTIAGFNANGAMPHYHATPESNTVIEGNGFLLIDSGGQYLGGTTDITRVVAIGQPSAEQKRDFALELKSVIALSVAQFPVGTRAPLLDAIARAPMWAAGLNYGHGTGHGVGYFLNVHEGPHNISWLTPPEPQTAMQLGMITSIEPGIYRPGKWGIRIENLVLNVPGDSTEFGEFIRFETLTLCPIDTRCLDKSHLTQVEIDWINNYHATVKQRLTPLVTGDALAWLERSTVAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GW76</accession>
    <name>A0A2S9GW76_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">L-serine dehydratase</fullName>
            <ecNumber evidence="9">4.3.1.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">S2091_3314</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>L-serine = NH4(+) + pyruvate</text>
            <dbReference type="Rhea" id="RHEA:19169"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="EC" id="4.3.1.17"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 9">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the iron-sulfur dependent L-serine dehydratase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.3.1.17" evidence="9"/>
    <dbReference type="EMBL" id="PUGF01000017">
        <property type="protein sequence ID" value="PRC91972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91972">
        <property type="protein sequence ID" value="PRC91972"/>
        <property type="gene ID" value="S2091_3314"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003941">
        <property type="term" value="F:L-serine ammonia-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029009">
        <property type="entry name" value="ASB_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004644">
        <property type="entry name" value="Fe-S_L-Ser_mono"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005130">
        <property type="entry name" value="Ser_deHydtase-like_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005131">
        <property type="entry name" value="Ser_deHydtase_bsu"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03313">
        <property type="entry name" value="SDH_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03315">
        <property type="entry name" value="SDH_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143548">
        <property type="entry name" value="SSF143548"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00720">
        <property type="entry name" value="sda_mono"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="9" id="KW-0312">Gluconeogenesis</keyword>
    <keyword evidence="6 9" id="KW-0408">Iron</keyword>
    <keyword evidence="7 9" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="8 9 12" id="KW-0456">Lyase</keyword>
    <keyword evidence="5 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SDH_beta" evidence="11">
        <location>
            <begin position="4"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="domain" description="SDH_alpha" evidence="10">
        <location>
            <begin position="187"/>
            <end position="452"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU366059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF03313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF03315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PRC91972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="458" mass="49031" checksum="0F6060569CDC6B8D" modified="2018-07-18" version="1">MPFSVFEVFRIGIGPSSSHTVGPMLAVNRFLQLLKPQLTEVARVQVDLYGSLALTGVGHGTNGAVILGLLGEQPHSVNPATAQDKVDLVRLDQQLLLDGTHEISFSCATDLLFHMRESLPQHPNGMRLTAFDADGNVLVKRAYFSIGGGAVQDEDEIDVSVKLEVTRSSEPCPFASAQDLLNWCETKQCSIADIVLDNELTYQDEQTTRLRLLEIWQVMHDCVERGLITEGTLPGGLSLKRRAPAMFRQAGHGSDGKLSIDFALMDILSAFAIAVNEENAAGGRVVTAPTNGSAGVIPAVLSYYTRFNPSANDDGIIRFLLTAAGIGMLYKRNASISAAEMGCQGEIGVSASMAAAGLVAVMGGTNLQVENAAEIAMEHFLGMTCDPLNGLVQVPCIERNSMGAIKAINAARMAMMSDGRHLVSLDQVIETMRQTGIDMQSKYKETSLGGLAVNVVFC</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GW83</accession>
    <name>A0A2S9GW83_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Efflux transporter, RND family, MFP subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_3300</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000017">
        <property type="protein sequence ID" value="PRC91958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91958">
        <property type="protein sequence ID" value="PRC91958"/>
        <property type="gene ID" value="S2091_3300"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006143">
        <property type="entry name" value="RND_pump_MFP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01730">
        <property type="entry name" value="RND_mfp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="25"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="domain" description="HlyD_D23" evidence="3">
        <location>
            <begin position="90"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC91958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="426" mass="45147" checksum="F6A94608B3F7786B" modified="2018-07-18" version="1">MNKPADIPSILILKNELAMPTKTKLSIAAAVVALLCGGLIINHFITGKSDAKTNVEVPVAPGTFRPSQSQLDALKILPVQSVSFRDEQITDGTIASNDDTTTPVFSPYSGHVAKLFAKLGDVVNKGAPLMAVEASEFVQGQNDLISAVAGLKTAHAQIKLTETSEQRQHDLYLAKAGALKDWLQSQADLATAQSNLRSAEVALSTVHNRLRILGKSDAEISTLETKPVTQQMNPEAIIRAPIAGTVILRQVGVGQNIQSASGGATNPVYSIANLSTVWLIANVRETDAPHMKIGTPVEVNVLAWPGRVFKAKIAWIAPSIDPNTHRLPVRAEVDNQDGALKPMMFATFRILTGDVATAPGVPQSAIVYEGSNAHVFVAEKDGSLALRPIQTGRVNGDLIEATSGLNAGEKIVTSGALFIDRAAESN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWB0</accession>
    <name>A0A2S9GWB0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3288</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000017">
        <property type="protein sequence ID" value="PRC91946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91946">
        <property type="protein sequence ID" value="PRC91946"/>
        <property type="gene ID" value="S2091_3288"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025528">
        <property type="entry name" value="BrnA_antitoxin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14384">
        <property type="entry name" value="BrnA_antitoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="98" mass="11178" checksum="B96489F4AAACE63B" modified="2018-07-18" version="1">MMSKKPNPELIDDENPEWTAKDFAKARPANEVLPQLFSAKVAQTMLKPRGRPRAEHPKERINIRLSHDVIAHFKASGDGWQTRIDAALREWLKTHSPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWK6</accession>
    <name>A0A2S9GWK6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3240</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000016">
        <property type="protein sequence ID" value="PRC92105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92105">
        <property type="protein sequence ID" value="PRC92105"/>
        <property type="gene ID" value="S2091_3240"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-binding" evidence="1">
        <location>
            <begin position="34"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding_C" evidence="2">
        <location>
            <begin position="422"/>
            <end position="495"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="514" mass="56600" checksum="D3199A125075D642" modified="2018-07-18" version="1">MSKNANLFSLIEANFPTDLSAPCLKMPQGTGFINEYSWDDLQKASAKIANLLTSLELPKGSRIAVQVEKSPEALILYLATLRAGFIFIPLNTAYQTAEMRYFIQDAQPAVVVCSPKNFGWLAQLAFQLGCSHVFTLDDKLPNQGSLLQRAAPLSSQFQTVQCEPDQIASIIYTSGTTGLSKGAMLSHQNLSANALTLQKTWHWQASDVLLHSLPLFHVHGLFISSNVALISGSTMIFLPKFDAAQVLKFLPESTVFMGVPTYYVRLLEQAGLTEQLCSTVRVFISGSAPLLAETFNAFQQRTAKTILERYGMSETNIISSNPYDGERLSNTVGQALPDVRIRIVNNEGQTCAEDEVGDIQVKGPNVFKGYWNRPEKTTQEFTKDGFFKTGDLGKLDKNAYLSIIGRSKDLIISGGYNIYPKEIELVLDALPGVVESAVIGLPHADFGEAVCAVLVCNMTLDSAQIIATLKNQIANFKVPKKIFMVKELPRNNMGKVQKNVLRDQYKESFSLLTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWS6</accession>
    <name>A0A2S9GWS6_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Aconitate hydratase</fullName>
            <shortName evidence="12">Aconitase</shortName>
            <ecNumber evidence="12">4.2.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">S2091_3093</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11 12">
            <text>citrate = D-threo-isocitrate</text>
            <dbReference type="Rhea" id="RHEA:10336"/>
            <dbReference type="ChEBI" id="CHEBI:15562"/>
            <dbReference type="ChEBI" id="CHEBI:16947"/>
            <dbReference type="EC" id="4.2.1.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <text evidence="12">Binds 1 [4Fe-4S] cluster per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate metabolism; tricarboxylic acid cycle; isocitrate from oxaloacetate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the aconitase/IPM isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.3" evidence="12"/>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92177">
        <property type="protein sequence ID" value="PRC92177"/>
        <property type="gene ID" value="S2091_3093"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00223">
        <property type="reaction ID" value="UER00718"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003994">
        <property type="term" value="F:aconitate hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047780">
        <property type="term" value="F:citrate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009098">
        <property type="term" value="P:leucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01580">
        <property type="entry name" value="AcnA_IRP_Swivel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.19.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.499.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044137">
        <property type="entry name" value="AcnA_IRP_Swivel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015931">
        <property type="entry name" value="Acnase/IPM_dHydase_lsu_aba_1/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001030">
        <property type="entry name" value="Acoase/IPM_deHydtase_lsu_aba"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015928">
        <property type="entry name" value="Aconitase/3IPM_dehydase_swvl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006249">
        <property type="entry name" value="Aconitase/IRP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018136">
        <property type="entry name" value="Aconitase_4Fe-4S_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036008">
        <property type="entry name" value="Aconitase_4Fe-4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000573">
        <property type="entry name" value="AconitaseA/IPMdHydase_ssu_swvl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11670">
        <property type="entry name" value="PTHR11670"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00330">
        <property type="entry name" value="Aconitase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00694">
        <property type="entry name" value="Aconitase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00415">
        <property type="entry name" value="ACONITASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53732">
        <property type="entry name" value="SSF53732"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01341">
        <property type="entry name" value="aconitase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00450">
        <property type="entry name" value="ACONITASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01244">
        <property type="entry name" value="ACONITASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="10" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="7 12" id="KW-0408">Iron</keyword>
    <keyword evidence="8 12" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4" id="KW-0432">Leucine biosynthesis</keyword>
    <keyword evidence="9 12" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aconitase" evidence="13">
        <location>
            <begin position="70"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="domain" description="Aconitase_C" evidence="14">
        <location>
            <begin position="700"/>
            <end position="827"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU361275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="PRC92177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="904" mass="98330" checksum="BA442C5F85E2642C" modified="2018-07-18" version="1">MSQDAFKTLKEFKISDSKKGKFYSLPALEKKLGVKISRLPVSIRIVLESVLRNCDGKKVTEEHVKQLANWGANADRNDEIPFVVSRVVLQDFTGVPLLADLAAMRNVAAKMGIKAKNIEPLVPVDLVVDHSVTIDHYREKKALDLNMKLEFSRNNERYQFMKWGMQAFDTFGVVPPGFGIVHQVNLEYLARGVHKIAKKDIYYPDTLVGTDSHTTMINGIGVVGWGVGGIEAEAGMLGQPVYFLTPDVVGVNLTGQLREGVTATDLVLTITELLRKEKVVGKFVEFYGTGTSTLTLTDRATIANMAPEYGATMGFFPVDEATLDYFKGTGRSKAEISAFEGYFKAQNLFGVPKQGDIDYTKEVSLDLSTVAPSLAGPKRPQDRIEIGNVKSTFRDLFSKPVSENGFNKKDEDLDAVYETSDGVKIKNGDIVIAAITSCTNTSNPSVMMAAGLLAKKAVEAGLKVSPHIKTSLAPGSRVVTKYLEAAGLLPYLEKLGFGVAAYGCTTCIGNAGDLTPAMNEAIIKNDIVASAVLSGNRNFEARIHGNIRSNFLASPPLVVAYAIAGNMSRDLMTEPVGRVKGKDIFLGDIWPTSAEINKVMKFAMNSKVFKENYADVKGAPGKLWENIKGGAEGDVYDWPKSTYIAEPPFFNDFEMEPKAAATTIIGARALGVFGDSITTDHISPAGSITETSPAGKWLLANNVLKADFNSYGSRRGNHEIMMRGTFANVRIKNRMIPLKEDGGQVEGGITTYQPTGEQMAIYDAAMKYVENGVPTMVFGGEEYGTGSSRDWAAKGTQLLGVKAVIVRSFERIHRSNLVGMGVLPLQFIGDDSVQTLGITGKETYDLKGLDGEIKPQQNATLVIHREDGTSQEVTVLLRIDTPIEVDYYKHGGILPFVLRQLLAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GX07</accession>
    <name>A0A2S9GX07_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2913</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92254">
        <property type="protein sequence ID" value="PRC92254"/>
        <property type="gene ID" value="S2091_2913"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="231"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="251" mass="26962" checksum="C90B961C1C5903D9" modified="2018-07-18" version="1">MSNTSGWSLTARLISKHFGVLGDKLSETIANFDPETATEADRDRLQGTLRETAQKLAAARASFDKEHSDVVNLQNLIATDSKATETLMARLQAGTISEATVTLFCDELEANKAKLPTEQQQEIDAKSYADELQQIVDGLSKQLADFDSAAKKAMQTLASAQAQKDLQSMRMERQSELDGLKGLGGQSTALSALTKRAQSVSNEAAGLKIVADIGQKPLDQAAEIDAIRKSVAQADTSGESALDRLKRLSAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GX17</accession>
    <name>A0A2S9GX17_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NAD dependent epimerase/dehydratase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2926</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92267">
        <property type="protein sequence ID" value="PRC92267"/>
        <property type="gene ID" value="S2091_2926"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016831">
        <property type="term" value="F:carboxy-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05257">
        <property type="entry name" value="Arna_like_SDR_e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045869">
        <property type="entry name" value="Arna-like_SDR_e"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="1">
        <location>
            <begin position="4"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="347" mass="39458" checksum="F219F4E53F1DA11F" modified="2018-07-18" version="1">MKKVLILGVNGFIGHHLSKRILETTDWHVYGMDMQTDRIGDILSHERMHFFEGDITINKDWVEYHVKKCDVILPLVAIATPSTYVKKPLRVFELDFEANLPIVRSAAKYGKHLVFPSTSEVYGMCHDDEFDPEESELVCGPINKPRWIYSCAKQLMDRVIWGYGMEDNLNFTLFRPFNWIGAGLDSIHTPKEGSSRVVTQFFGHIVRGENISLVDGGQQKRAFTYIDDGIDALMKIIANEDGIATGKIYNIGNPDNNFSIRELATMMLELAAQYPEYAATAKQVKIVETTSAAYYGKGYQDVQNRVPKITNTKEELKWAPHTTMPDTMRNIFDAYRSQVAEARALMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GX19</accession>
    <name>A0A2S9GX19_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3122</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92206">
        <property type="protein sequence ID" value="PRC92206"/>
        <property type="gene ID" value="S2091_3122"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024447">
        <property type="entry name" value="YXWGXW_rpt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12779">
        <property type="entry name" value="WXXGXW"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015646556" evidence="1">
        <location>
            <begin position="22"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="119" mass="13156" checksum="B59776A1F4181DD5" modified="2018-07-18" version="1">MKNSTLICSAIVLAAATLVSGCVVTPAPYHYRAEVVYPDVAPPPVIVYTAPPAPQVEVVGVAPVSGYFWISGVWLWEGGHHVWHSGHWAAPRPGYAWVPHHWHQEGNAWHMDGGHWQRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GX47</accession>
    <name>A0A2S9GX47_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">tRNA 2-selenouridine synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3152</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92236">
        <property type="protein sequence ID" value="PRC92236"/>
        <property type="gene ID" value="S2091_3152"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043828">
        <property type="term" value="F:tRNA 2-selenouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002098">
        <property type="term" value="P:tRNA wobble uridine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017582">
        <property type="entry name" value="SelU"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="SSF52821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03167">
        <property type="entry name" value="tRNA_sel_U_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0711">Selenium</keyword>
    <feature type="domain" description="Rhodanese" evidence="2">
        <location>
            <begin position="22"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="352" mass="39937" checksum="BAF19C7103CE4DB3" modified="2018-07-18" version="1">MKYPALLPFSELVNQLDQFDSIIDVRSPAEFALDHIPGAINCPVLNDLERIRVGTMYKQVNAFEAKKVGAALVAKNIALHIEEQFLQYPREWKPLIYCWRGGNRSGSMALILAKIGWPVVQLDGGYKAYRQHINTELSQLIGQFQYRVVCGTTGSGKSRLLQALHTQGAQVLDLEKLAEHRGSVLGDLPSTAQPSQKAFESAIWLTLRKFDSSKVVYIESESKKVGNLRVPDHLISCMRNSACISLQLPINLRVALLMQDYAYFISQPNELMKRLHYLTPLHGKEKIRHWQNLSEQDLLHDLVQELIEVHYDPSYLRSIERNFPQLGGMPTIHLNGIAELDFLQLAERLLAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GX70</accession>
    <name>A0A2S9GX70_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2959</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92300">
        <property type="protein sequence ID" value="PRC92300"/>
        <property type="gene ID" value="S2091_2959"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="291" mass="32560" checksum="67BCF1D08190B2D6" modified="2018-07-18" version="1">MISHEALNVFVEAANSGSFSAAARKLGKRQSTVSEAIANLEIDLGVSLFDRRTRRPTLTAQGRSMLVHAQQVLEAQHRLSIAARLLVGGQEAQLSFALSDTYQSNVFEVMLKKIEQRFPDLQLECLIAEDHDAVELVQENRVQLALITAQAEYPPDISFDTLSDPSEIGLFVSAGHALTNQSTISNAMLSATRELRLNTFADDAYSKRTSLSWSSSNYLILLEMTELGFGWAKLPRWLVKRFAETKLVELRTGGWPRQIPMHVIWSRQHNLGPAACWMRDNFLTSTVELQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXF3</accession>
    <name>A0A2S9GXF3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2766</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92391">
        <property type="protein sequence ID" value="PRC92391"/>
        <property type="gene ID" value="S2091_2766"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13673">
        <property type="entry name" value="Acetyltransf_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="10"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="155" mass="17450" checksum="36D66EBFAD6ED55B" modified="2018-07-18" version="1">MTQIIKWQCASFNELTGAQIYAILQARSEVFIMEQNCVYQDMDGLDLSTLHVIGWAEDEKVAAYLRIVAPNIKFPEPSIGRVISTSAFRGSGIGRQLITEGLKQLEAHYPSQAVRISAQAYLQEFYKSFGFVAVSEEYLEDDIPHIEMLRPVSSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXG6</accession>
    <name>A0A2S9GXG6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Putative branched-chain amino acid permease (Azaleucine resistance)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_2775</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the AzlC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92400">
        <property type="protein sequence ID" value="PRC92400"/>
        <property type="gene ID" value="S2091_2775"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011606">
        <property type="entry name" value="Brnchd-chn_aa_trnsp_permease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34979">
        <property type="entry name" value="PTHR34979"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03591">
        <property type="entry name" value="AzlC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="34"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="64"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="88"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="155"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="181"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="204"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="227"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010735"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC92400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="263" mass="28472" checksum="9650926A5358EF91" modified="2018-07-18" version="1">MNAYLTASNPSNLPPEQLAEVEQNAFRSGVKACSPTLIGIAAWGLVVGVAMIKTHFTIMQALGMTLFVFAGSAQLAALPLIAVGAPVWVIFVTGLVVNLRFVIFSVILAPHFAHLSFRQRAFWGYMTGDVSMVYFMQRYPTEQAEAGKFAYLKGLLIPNWAAWQIGSIAGIFLGSQIPEEWGVGFAGSLAILCILLPMVMNRSTLIGVIVAGAIALLTIHWPYKLGMLLAVLIGMAAAMIWEEWHEKSSADKKQNQGTNKGNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXM9</accession>
    <name>A0A2S9GXM9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Proline racemase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2849</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the proline racemase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92474">
        <property type="protein sequence ID" value="PRC92474"/>
        <property type="gene ID" value="S2091_2849"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008794">
        <property type="entry name" value="Pro_racemase_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33442">
        <property type="entry name" value="PTHR33442"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05544">
        <property type="entry name" value="Pro_racemase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029792">
        <property type="entry name" value="Pro_racemase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00028">
        <property type="entry name" value="Proline_Racemase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="313" mass="33446" checksum="FA57F05E8B6F134A" modified="2018-07-18" version="1">MQTIQIIDSHTGAEPTRLVLQGGPELGKGSMADRLSNFKQNFDAFRRGVVCEPRGSDVIVGALLCTPFDPSCSLGVIFFNNTGYLGMCGHGTIGLIASLAYKGMLQIGVHRIDTPVGVVQTTLHEDGSVTVVNVPAYRYKKAVEINVPGLGVMVGDVAWGGNWFFLVNNYPAPLQFKNVAELTHHAENVRIALVAAGVTGANGAEIDHIEFFSASDTPGCDSRNFVLCPGLAYDRSPCGTGTSAKLACLAADDKLAEGALWHQESIVGSMFDGSYQRIDAEKVQPSIRGRAYVMAEATLLIDPQDPFRWGIAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXP2</accession>
    <name>A0A2S9GXP2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Glycosyl hydrolase family 9</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_2853</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92478">
        <property type="protein sequence ID" value="PRC92478"/>
        <property type="gene ID" value="S2091_2853"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008810">
        <property type="term" value="F:cellulase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02850">
        <property type="entry name" value="E_set_Cellulase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004197">
        <property type="entry name" value="Cellulase_Ig-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001701">
        <property type="entry name" value="Glyco_hydro_9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02927">
        <property type="entry name" value="CelD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00759">
        <property type="entry name" value="Glyco_hydro_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="SSF48208"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="SSF81296"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="3" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="1 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CelD_N" evidence="5">
        <location>
            <begin position="44"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC92478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="657" mass="70025" checksum="8D12CE193E525A2B" modified="2018-07-18" version="1">MKLQNNKYESAHRYAPEKFHIKIGKVIGFCMLCAALPAWAVTGYLRINQVGYETDVAAQAYLMTSSPVSDVSFHVINSSGDTVTSGTVGAKTGTWGSYTVYPVNFTVADSGKYSISVSGPVSTSSPVFTVDTSTNLYSQALVNTLSFYQNQRDGSNFIPSALRTAAGHLNDANATVYKTPPITNDNITAKLSPTGQKINAEGGWWDAGDYLKFVQTHSYTVALMLTGVRDFPNQMGAGSAKSNFTSEAEFGLNWLQQMWDDSTQTLYYQVGIGTDFTVNSDVSDHDLWRLPQVDDNYVPPSATGLTVAQIPYIRNRPVFVSGPAGSKISPNLAGRLAADFALCYQVFKLSNPSYANKCLLEAEHVFALANTSPGTLLTVAPYDFYPETEWRDDMELGATELYFALQAGSLPAGLPVTNASYYLTQAANWAHAYITGPNDQADTLNLYDTSGLAHFELYRAIGMAGKPTLAVTQAALLSDLSSQMSTSVSQSGDPFGSPIGWKNGDTASHVSGLSVMASEYGYLTNSSSYTTDANRWAGNLLGANAWGVSFIVGDGTTFPNCIQHQVANISGSMNGKGNVLAGAVVEGPTNTASSGSLPGMVACPANGVDIYAKFNASGAVYRDNMQSYATNEPAIDLTAASMLMFAWQIAGAPNGTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXX9</accession>
    <name>A0A2S9GXX9_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Beta-galactosidase</fullName>
            <ecNumber evidence="5">3.2.1.23</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_2627</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides.</text>
            <dbReference type="EC" id="3.2.1.23"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the glycosyl hydrolase 35 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.23" evidence="5"/>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92572">
        <property type="protein sequence ID" value="PRC92572"/>
        <property type="gene ID" value="S2091_2627"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004565">
        <property type="term" value="F:beta-galactosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026283">
        <property type="entry name" value="B-gal_1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031330">
        <property type="entry name" value="Gly_Hdrlase_35_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019801">
        <property type="entry name" value="Glyco_hydro_35_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001944">
        <property type="entry name" value="Glycoside_Hdrlase_35"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23421">
        <property type="entry name" value="PTHR23421"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01301">
        <property type="entry name" value="Glyco_hydro_35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006336">
        <property type="entry name" value="B-gal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00742">
        <property type="entry name" value="GLHYDRLASE35"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="SSF49785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01182">
        <property type="entry name" value="GLYCOSYL_HYDROL_F35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 5 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyco_hydro_35" evidence="7">
        <location>
            <begin position="45"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="4">
        <location>
            <position position="197"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4">
        <location>
            <position position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009809"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR006336-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01301"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC92572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="635" mass="70884" checksum="D3509C1F97746530" modified="2018-07-18" version="1">MDRRLFLNMSGLSLLSTLSPLFPIVSYAEDTTVKGEFSFSEDGSQFLLNKAPFQIRSGEMHPARIPYQYWLHRIKMAKAMGMNTIAVYLIWNFHETSEGVFDFASASHDIAAFICLCQDEGVWVLLRPGPYVCGEWDLGGIPSYLLREPDIKLRANSTRAPQYMAAATRYIAKLAEQIKPLMINNGGPILMLQIENEFGSYGNDVAYLEELRQLWIQQGISGPFYTQDGLEQLQKNKTLVKGGALGLSGGELADINIVRKEYPSVPAMCGELYPGWLTHWGEPEFQGTNVDVSATLNDFMTHNISFNMYVIHGGTNFGFTAGANTEKGQYQPDITSYDYGAPITEQGMPTSAYFKYRKLIAEKLSVTLPILPAPIQTLKKNAAHQLTPKLFASIWDNLPAAIHTEQPQSFEALGQNNGFVIYRKQLIGHVSGHLHVPKLNDYGTVFLNDRYLGGFSRTLLPAAVAGKLNMAGRNQTLVMNSAHESPTLDVLVEAMGHINYGSELGDRKGILQAVSLQHPEQGIYEIVDWQTFLLPMDSKFIAGLKGGNPSSKKAGLFFKLNLKLDQLGDTFIDMQRWTKGVVWVNGHNLGRYWKIGPQHRLYCPAPWLKKGENEILIFDLHQLKAEPIALERTLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GY62</accession>
    <name>A0A2S9GY62_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">NinB protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2706</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92651">
        <property type="protein sequence ID" value="PRC92651"/>
        <property type="gene ID" value="S2091_2706"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3790.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036619">
        <property type="entry name" value="NinB_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008711">
        <property type="entry name" value="Recombinase_NinB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05772">
        <property type="entry name" value="NinB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103370">
        <property type="entry name" value="SSF103370"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="133" mass="14837" checksum="D26F460FC8D199B2" modified="2018-07-18" version="1">MKRPFVILNEQIRQSAIQHVSTLPLGSGLTTDTEPSRTLDQNAAQWPILAAFSKQLDWPINGQMTKMTDEEWKDVLTAAFKQETTRLAMGLDGGVVMLGQRTSKFGKKVFSEWIEFLHAVAAQRGVVVYEDAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GY76</accession>
    <name>A0A2S9GY76_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 7">Signal peptidase I</fullName>
            <ecNumber evidence="3 7">3.4.21.89</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">S2091_2661</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>Cleavage of hydrophobic, N-terminal signal or leader sequences from secreted and periplasmic proteins.</text>
            <dbReference type="EC" id="3.4.21.89"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Membrane</location>
            <topology evidence="8">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the peptidase S26 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.89" evidence="3 7"/>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92606">
        <property type="protein sequence ID" value="PRC92606"/>
        <property type="gene ID" value="S2091_2661"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006465">
        <property type="term" value="P:signal peptide processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06530">
        <property type="entry name" value="S26_SPase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036286">
        <property type="entry name" value="LexA/Signal_pep-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000223">
        <property type="entry name" value="Pept_S26A_signal_pept_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019758">
        <property type="entry name" value="Pept_S26A_signal_pept_1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019757">
        <property type="entry name" value="Pept_S26A_signal_pept_1_Lys-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019756">
        <property type="entry name" value="Pept_S26A_signal_pept_1_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019533">
        <property type="entry name" value="Peptidase_S26"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43390">
        <property type="entry name" value="PTHR43390"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10502">
        <property type="entry name" value="Peptidase_S26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00727">
        <property type="entry name" value="LEADERPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51306">
        <property type="entry name" value="SSF51306"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02227">
        <property type="entry name" value="sigpep_I_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00501">
        <property type="entry name" value="SPASE_I_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00760">
        <property type="entry name" value="SPASE_I_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00761">
        <property type="entry name" value="SPASE_I_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 7" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="79"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S26" evidence="9">
        <location>
            <begin position="79"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="110"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00019232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR600223-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF10502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC92606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="311" mass="35694" checksum="254D75CE7F6053B0" modified="2018-07-18" version="1">MNLQSILGNFALILFILTIFTGAIWFLDVFVLAKQRKAAADAALAEFDSRRAKLSAEGLKLETSNREELKATLLRQPAWVEYTGSFFPVILLVFCLRSFLYEPFKIPSSSMLPTLLVGDLILVNKFTYGIRLPILNKKIIEINQPQRGDVMVFKYPKDMSLDYIKRVIGVPGDKITYKNKRLTVNGQEVTYKELPDFLDEERLTYAKHYEENLTGVHHQILNDERAPTYVSGDHYFPQSELCSYDTEGFTCTVPKGHYFMMGDNRDNSADSRYWGFVPDENIVGKAFGIWMNQNVITNFDFSKLKRIGSFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYR0</accession>
    <name>A0A2S9GYR0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2526</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92796">
        <property type="protein sequence ID" value="PRC92796"/>
        <property type="gene ID" value="S2091_2526"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="393" mass="44986" checksum="D0305C45D5B675D8" modified="2018-07-18" version="1">MNANAFYRPIISAPDRLIRAPLLEWKRTCSGSLANIIRKNDMDVEKIAVDLNCLALLETYQGHYDFSLRLCTAQIRFWKKFANQPGHSQDLSKVIQPWINIIRLERWQNKWENASALYRELKQENHTVPGTLNQRYDIECNLKQLCELDQKFDYVNLLNVVYWREYANLLLQSNALDELQQFLGAGFAANINGSLKVSLLEILLSYLTKIGSYENALSILKKIKAGQSGEFWLHFKILEMFLSERTNQANASLLIMQTYQAAISEKYIQRNSYGLNLLHSISHVFKELDIVDLEIDLLNKTAKIAEELGDEVTLFEVMSRLADLHEIPQKIVFDKFAHSSYALIRGRLGLPLSSTAELEESRQLVLAVEAFAQLDYVSCLDLLQAESGAELFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYU2</accession>
    <name>A0A2S9GYU2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_2311</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92894">
        <property type="protein sequence ID" value="PRC92894"/>
        <property type="gene ID" value="S2091_2311"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0110001">
        <property type="term" value="C:toxin-antitoxin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004540">
        <property type="term" value="F:ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008201">
        <property type="entry name" value="HepT-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01934">
        <property type="entry name" value="DUF86"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-1277">Toxin-antitoxin system</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC92894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="123" mass="14379" checksum="36F05DF3377E16E3" modified="2018-07-18" version="1">MSKNELRVPDYLGHIQQAIERIHRYIEDLDEVVFLNNEMIQDAVIRNIEIVGEASNNIVKFAPDFAALHSEIPWSVIYAMRNRVAHAYHKVDLELVWNMIQNDLPVLHQQIVTLLNNLDHPHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZ27</accession>
    <name>A0A2S9GZ27_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">Flagellar transcriptional regulator FlhC</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">flhC</name>
        <name evidence="6" type="ORF">S2091_2380</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="4">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Heterohexamer composed of two FlhC and four FlhD subunits. Each FlhC binds a FlhD dimer, forming a heterotrimer, and a hexamer assembles by dimerization of two heterotrimers.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4 5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 5">Belongs to the FlhC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92963">
        <property type="protein sequence ID" value="PRC92963"/>
        <property type="gene ID" value="S2091_2380"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044781">
        <property type="term" value="P:bacterial-type flagellum organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045893">
        <property type="term" value="P:positive regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902208">
        <property type="term" value="P:regulation of bacterial-type flagellum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01891">
        <property type="entry name" value="FhlC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007944">
        <property type="entry name" value="FlhC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05280">
        <property type="entry name" value="FlhC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003159">
        <property type="entry name" value="FlhC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0010">Activator</keyword>
    <keyword evidence="3 4 5" id="KW-1005">Bacterial flagellum biogenesis</keyword>
    <keyword evidence="6" id="KW-0966">Cell projection</keyword>
    <keyword evidence="6" id="KW-0969">Cilium</keyword>
    <keyword evidence="1 4 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0282">Flagellum</keyword>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 5" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="binding site" evidence="4">
        <location>
            <position position="138"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="141"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="158"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="161"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR003159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC92963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="185" mass="21074" checksum="73B359CC60870FE8" modified="2018-07-18" version="1">MGKKSVITEAHEIQLAIELVNLGARLQLLESETSLSRERLLKLYKELKGVSPPKGMLPFSTDWFLTWQPNIHASLFMNIHKYLIEHADVKGIEAIVKAYKLYLEQMPGNPNQEQVLSLTRAWTLVRFFESKMLSLACCCKCGGHFVSYKYDLHKNYACGLCHMPSRAGKLKKVKEVEKAAYELVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZ81</accession>
    <name>A0A2S9GZ81_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2128</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93042">
        <property type="protein sequence ID" value="PRC93042"/>
        <property type="gene ID" value="S2091_2128"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010323">
        <property type="entry name" value="DUF924"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06041">
        <property type="entry name" value="DUF924"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="179" mass="20812" checksum="342F4487BABDDFF7" modified="2018-07-18" version="1">MSYHNIIRFWFEEIDTKQWYKKDLAFDLLLQQKFGQLHQSAIAGELEHWRANAQGRLAEIIILDQFSRNLGRNTPAAFTCDSLALCLAQHAVAVHADQELNPIQRAFIYMPFMHSESVLIHEQALQLFAQPGLENSLHFEQRHRDIILRFGRYPHRNAILGRVSTPEEIEFLEQPGSSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZB3</accession>
    <name>A0A2S9GZB3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Flagellar motor protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_2383</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MotB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92966">
        <property type="protein sequence ID" value="PRC92966"/>
        <property type="gene ID" value="S2091_2383"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07185">
        <property type="entry name" value="OmpA_C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025713">
        <property type="entry name" value="MotB_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006665">
        <property type="entry name" value="OmpA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036737">
        <property type="entry name" value="OmpA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13677">
        <property type="entry name" value="MotB_plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00691">
        <property type="entry name" value="OmpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103088">
        <property type="entry name" value="SSF103088"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51123">
        <property type="entry name" value="OMPA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0966">Cell projection</keyword>
    <keyword evidence="8" id="KW-0969">Cilium</keyword>
    <keyword evidence="8" id="KW-0282">Flagellum</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="28"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="domain" description="OmpA-like" evidence="7">
        <location>
            <begin position="159"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="73"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="284"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC92966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="318" mass="34048" checksum="69A6A0B40948E3FD" modified="2018-07-18" version="1">MANEELRPIIVKRIKKVAGGHHGGAWKIAYADFVTAMMAFFLLMWLLGSTTKGTLQGIAEYFQTPLKIAMSGGEGSGDSSSVIKGGGRDLSASEGQVKKSDAAKNKKNYNLKDAEAALALADAAHLKALKEKIEAVIDANPVLKQYKKQLQLDMTTDGLRIQILDDQNRPMFASAKAELEPYTKEILDEIGVALNEVPNRISLSGHTDATPYSSGGRGYSNWELSADRANASRKELIAGGMDESKVLRVVGLSSAVLFNKENPLDPINRRISILVMNKQAELSASQDGGAIDVGPPAAAATESPPEKTDDVKPEPASK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZG5</accession>
    <name>A0A2S9GZG5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC-type anion transport system duplicated permease component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_2215</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93129">
        <property type="protein sequence ID" value="PRC93129"/>
        <property type="gene ID" value="S2091_2215"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="26"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="68"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="107"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="191"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="244"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="340"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="372"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="414"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="455"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="489"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="548"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="69"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="380"/>
            <end position="566"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC93129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="580" mass="65710" checksum="A38B1A038F30DCCD" modified="2018-07-18" version="1">MEHSQFNGQAWQRNNSASHQPNRWDWMALPIIIGILFFLAFGASQMATPYQVGMPLEITLDPWYLPYYLLRTTLRMMTALLLSLIFSFVFAALAGRYRLAEKIMVPALDILQSIPVLGFLTITVTGFIALFPGSLLGVECAAIFAIFTSQAWNMAFSMYQSMRTVPSDLREAARIFHLSSWQRFWRLELPFAMPALLWNMMMSMSGGWFFVVACETITVSNHNIQLPGIGSYIAYAINQENYSAMGWAIGAMLLGILMYDQLLFRPLIAWANKFKYEQTGDQGGQESWFLTLLRRTNAVQGVTARLIEYFERGLLLFRRNYDGTSIMARPQRINPTFERVSDAVIAALVMFACWEIGSYIHSAVGWGEVLRVFWYGFLTLLRVTIMITLASLVWVPIGVWIGLNPKYTERLQPIAQFMAAFPANFMFPLVVIVLVKYHLNPDIWLTPLMVFGTQWYILFNVIAGASIIPTELVYAADNFGLSGWMRWKRFLLPAVFPSFVTGAITASGGSWNASIVSEYVTWGNNTLTATGLGSYIAQVTATGDFPRVALGISVMCFFVIACNRFIWRKLYRIAEEKMSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZL1</accession>
    <name>A0A2S9GZL1_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DUF4149 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_2229</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93143">
        <property type="protein sequence ID" value="PRC93143"/>
        <property type="gene ID" value="S2091_2229"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025423">
        <property type="entry name" value="DUF4149"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13664">
        <property type="entry name" value="DUF4149"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="48"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="77"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="116"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4149" evidence="5">
        <location>
            <begin position="12"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF13664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC93143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="148" mass="16319" checksum="ADA7B76E0BCFCE59" modified="2018-07-18" version="1">MTTAWDRAQLLITTAWVGSLWTIGYLVAPTLFKTLTDSSLAGTIAGQLFYVEACLSVVCALLLLGIALYQRKRLPKLVLGMLLCTILGYFVLHPFMAELRAAGLTNPDNKWQFGMLHAISSGFYLMQSVLGAMLVLEHLNKNVEVALR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZU1</accession>
    <name>A0A2S9GZU1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1993</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93255">
        <property type="protein sequence ID" value="PRC93255"/>
        <property type="gene ID" value="S2091_1993"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="251" mass="28572" checksum="30E20BEF83B0D933" modified="2018-07-18" version="1">MAEQEISKHTLNALKTIANKENDIWHKLREVALEIFIIVFAVTLSIWMHEQGEHRHEQQQVKSFLIGLKADIQSDIADMNDNIQSYQEDDAIYSYLANLGPATTLDKVKFEDAYAHATVGFNRFFIPHNSRYEGFKSSGKLTSIEDDKLLQHIVSLHEEAMPVIHNSESGWIYNQNSLIHYLDVALDAPEGSDLPFKLITAPKGKRLSKSMIASPQLYERYHTYIELGTQIIKEIELAYPDSAVKQVAVKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZV1</accession>
    <name>A0A2S9GZV1_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Endolytic peptidoglycan transglycosylase RlpA</fullName>
            <ecNumber evidence="3">4.2.2.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rlpA</name>
        <name evidence="7" type="ORF">S2091_2003</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the RlpA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.2.-" evidence="3"/>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93265">
        <property type="protein sequence ID" value="PRC93265"/>
        <property type="gene ID" value="S2091_2003"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008932">
        <property type="term" value="F:lytic endotransglycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042834">
        <property type="term" value="F:peptidoglycan binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000270">
        <property type="term" value="P:peptidoglycan metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1070">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02071">
        <property type="entry name" value="RlpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034718">
        <property type="entry name" value="RlpA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009009">
        <property type="entry name" value="RlpA-like_DPBB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036908">
        <property type="entry name" value="RlpA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012997">
        <property type="entry name" value="RplA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007730">
        <property type="entry name" value="SPOR-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036680">
        <property type="entry name" value="SPOR-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03330">
        <property type="entry name" value="DPBB_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05036">
        <property type="entry name" value="SPOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110997">
        <property type="entry name" value="SSF110997"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50685">
        <property type="entry name" value="SSF50685"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00413">
        <property type="entry name" value="rlpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51724">
        <property type="entry name" value="SPOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="7" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="1 3" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015793401" description="Endolytic peptidoglycan transglycosylase RlpA" evidence="3">
        <location>
            <begin position="31"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="domain" description="SPOR" evidence="6">
        <location>
            <begin position="297"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="29"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="31"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC93265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="375" mass="39761" checksum="FD1833457E0E703F" modified="2018-07-18" version="1" precursor="true">MHSLKSRSQLVAITLLGLLLAACGSAPKVAAPSSAGSTNSTKTSSIPSAAGQPAPNLPKAGSGRGAYYKDDGPGENPPPGLELTLDAEPKLEPYSVSGNKPYVVFGKTYTPMIDDRAFSQRGTGSWYGKKFHGQRTSSGELYDMYKMTAAHPTLPIPSYARITNISNGRQVIVKINDRGPFHTNRIVDLSYTAALKLDYLGKGSSELLLERLLPADIEKMAENKKNNVGDKLASAPPPVVTSIVAPTVVVPVIAEQAAAAPVRVVPAATDTASFEALVATHASSEDVAQVPVVISTPNNTSGFYLQFGAFGLRSNAEATFTHLQSKLKQLPAFEIVQQGTLYRLFSGPFASRDEANNALQLAMSIGIPKPVIVQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZZ1</accession>
    <name>A0A2S9GZZ1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2040</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93302">
        <property type="protein sequence ID" value="PRC93302"/>
        <property type="gene ID" value="S2091_2040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="136"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="186" mass="20479" checksum="09440719341CB579" modified="2018-07-18" version="1">MNTKIMLAVCGLSSVLLLGCKTPPTSEVIVPSVPTSPVIAPVAAPVHTEIDDLLAYYQSNHQMSQTELLKNLVDLNSALKSPHSDLQKAIILGCLRGPVELSRATVLLDGIIKSSDPQAQRLLPLATLLYANYSEWRRLDDALDKQNQQLKEAQRRADQLSQKLEDLKAIEQQLPSRPHASNESRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H008</accession>
    <name>A0A2S9H008_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 14">Catalase</fullName>
            <ecNumber evidence="4 14">1.11.1.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">S2091_2049</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 14">
            <text>2 H2O2 = 2 H2O + O2</text>
            <dbReference type="Rhea" id="RHEA:20309"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="EC" id="1.11.1.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 13">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the catalase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.6" evidence="4 14"/>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93311">
        <property type="protein sequence ID" value="PRC93311"/>
        <property type="gene ID" value="S2091_2049"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004096">
        <property type="term" value="F:catalase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042744">
        <property type="term" value="P:hydrogen peroxide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08156">
        <property type="entry name" value="catalase_clade_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018028">
        <property type="entry name" value="Catalase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040333">
        <property type="entry name" value="Catalase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024708">
        <property type="entry name" value="Catalase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024711">
        <property type="entry name" value="Catalase_clade1/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011614">
        <property type="entry name" value="Catalase_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002226">
        <property type="entry name" value="Catalase_haem_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010582">
        <property type="entry name" value="Catalase_immune_responsive"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020835">
        <property type="entry name" value="Catalase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11465">
        <property type="entry name" value="PTHR11465"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00199">
        <property type="entry name" value="Catalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06628">
        <property type="entry name" value="Catalase-rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038928">
        <property type="entry name" value="Catalase_clade1-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00067">
        <property type="entry name" value="CATALASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01060">
        <property type="entry name" value="Catalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56634">
        <property type="entry name" value="SSF56634"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00437">
        <property type="entry name" value="CATALASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00438">
        <property type="entry name" value="CATALASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51402">
        <property type="entry name" value="CATALASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 13 14" id="KW-0349">Heme</keyword>
    <keyword evidence="11 14" id="KW-0376">Hydrogen peroxide</keyword>
    <keyword evidence="10 13 14" id="KW-0408">Iron</keyword>
    <keyword evidence="8 13 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6 14" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Catalase" evidence="16">
        <location>
            <begin position="7"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="active site" evidence="12">
        <location>
            <position position="54"/>
        </location>
    </feature>
    <feature type="active site" evidence="12">
        <location>
            <position position="127"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="13">
        <location>
            <position position="337"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000720"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00014132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR038928-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR038928-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU000498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="SMART" id="SM01060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="PRC93311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="478" mass="53864" checksum="6D2497DF859D8204" modified="2018-07-18" version="1">MTDKKLTTAAGAPVPDNQNTMTAGARGPVLLQDVWMLEKLAHFNREVIPERRMHAKGSGAYGSFTVTNDISKYTRAKLFSSVGKKTDLFARFTTVAGERGAADAERDIRGFSVKFYTEEGNWDLVGNNTPVFFLRDALKFPDLNHAVKRDPRTNLRSATNNWDFWTSLPEALHQVTIVMSDRGLPATYRHMHGFGSHTFSFINAQNERSWVKFHFRSEQGIKNLTDAEAEKLVGQDRESHQRDLFDSLEKGDFPKWTLLVQIMPEQDASKVPYNPFDLTKVWPHKDYPLIEVGVMELNRNPENFFAEVEQSAFNPAAVVPGISFSPDKMLQARLFAYGDAQRYRLGVNHHQIPVNAPRCPVHSYHRDGAMRVDNNHGGTIGYEPNSYGQWQEQPDFREPPLSVEGAADHWNHRVDADYYSQPGALFRLMSSAQQQVLFENTARSLGDAPLAIKQRHVDNCSKADPAYGVGVAKALGLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H075</accession>
    <name>A0A2S9H075_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Tetratricopeptide repeat</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1771</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93384">
        <property type="protein sequence ID" value="PRC93384"/>
        <property type="gene ID" value="S2091_1771"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015541016" evidence="1">
        <location>
            <begin position="32"/>
            <end position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="425" mass="45896" checksum="8F4D06116D86C4B1" modified="2018-07-18" version="1">MTKFRNARLSAIAVVLGLSAASTLLLSSAYAETPAASAATPAETLRPEISKSLAAAQVLFEAKNYPDALAKLAETDAIANKTSYETYAVERSRGNYLMASGDKTKAAQAFEAVVGAHYLVRADQLNMIQAISQLYFQLSNYPLTISWMERYLAEGGTDPRSKIVLNQARYLNKDYAIAFKGISAEVQDDIAAGHVPSEQNLKLLLSCMGLLNDKEGTLKALEQLNSYYPNSKNWLYLVSQLHSKPGYSDRLALDVYRLKQELALMSVAADYTDMSELATRAGLPAEAKKALDEGFAAGLLDKGPDAKKHASLLATANKHAEDDLKTMQQGEASANKNKGGAGLVNLGMAYATAGQFDKAISLIEQGISKGGLTNLEDAKLHLGIVYYWAGKKDEAIKQLSTVQGADGTADLARYWVMQINHPLAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0D0</accession>
    <name>A0A2S9H0D0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1826</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93439">
        <property type="protein sequence ID" value="PRC93439"/>
        <property type="gene ID" value="S2091_1826"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="88"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="107" mass="12379" checksum="BB14211DAC86A8B8" modified="2018-07-18" version="1">MQARALKPSEQMRQQQVSATTQMRNKNVSQVMDTRPTQIAQRRLQETSNSSVRALQLKTVQAKMTAQRQEKEGLLQGKFEAVQRVEEEEPLQAKFEPVQRVEEEEPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0T5</accession>
    <name>A0A2S9H0T5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1863</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93476">
        <property type="protein sequence ID" value="PRC93476"/>
        <property type="gene ID" value="S2091_1863"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008620">
        <property type="entry name" value="FixH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05751">
        <property type="entry name" value="FixH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="24"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="182" mass="20559" checksum="F59CADE10046A9A5" modified="2018-07-18" version="1">MRMTTPATPLIDRVNSLKPWYKHLWPWLLMAGPFLVVIAASYTGWIAFTRQDAMVVDDYYKQGNAINKDLRRDAAATNLGLTLNASYDAAQGKLHGRLLSFGQPIAGKVIIQLSHATQPEKDRQLEAQADQRGEFEAELPALDLGRWEMSVGDEKHTWRLTGTWMWPQQRTIDLKADLPAAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H145</accession>
    <name>A0A2S9H145_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 11">Cell division protein FtsX</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">S2091_1689</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Part of the ABC transporter FtsEX involved in cellular division.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Forms a membrane-associated complex with FtsE.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cell inner membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 11">Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93688">
        <property type="protein sequence ID" value="PRC93688"/>
        <property type="gene ID" value="S2091_1689"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004513">
        <property type="entry name" value="ABC_transpt_FtsX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040690">
        <property type="entry name" value="FtsX_ECD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47755">
        <property type="entry name" value="PTHR47755"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18075">
        <property type="entry name" value="FtsX_ECD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003097">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="11 15" id="KW-0132">Cell division</keyword>
    <keyword evidence="11" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="7 11" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10 11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="26"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="180"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="232"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="282"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX_ECD" evidence="14">
        <location>
            <begin position="62"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="13">
        <location>
            <begin position="212"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00021907"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR003097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF18075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="PRC93688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="310" mass="33546" checksum="589261DC61D31B63" modified="2018-07-18" version="1">MKTWLRQHAAASVDAAKQILSAPGNFFFNVLVTAFALSLPIAGLTLIENVRPISSQLSIAPELSLFLKTDLSRSNATAFADTIKKLIKTTPAKVVFIPRETALAALQNSSGLGDVLTTLGDNPLPDAYVLSFEEHFELTTQQSSPEKIEALAAQLQKLPEVDHVQIDSNWIKRLAALMHLAQFVLAALAIALSVVVITVVFNATRLQVLSHRAEIVVIRLLGATSQYIRRPYYYTGALLGLAAGLTALAIVAAALQPMNQAIVEFASLYGSEFHLTPLNLTFSVYLLVSSALLGLFGAFLSVRHQVKQLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H163</accession>
    <name>A0A2S9H163_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Phosphopantetheine adenylyltransferase</fullName>
            <ecNumber evidence="6">2.7.7.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Dephospho-CoA pyrophosphorylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Pantetheine-phosphate adenylyltransferase</fullName>
            <shortName evidence="6">PPAT</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">coaD</name>
        <name evidence="8" type="ORF">S2091_1684</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>(R)-4'-phosphopantetheine + ATP + H(+) = 3'-dephospho-CoA + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:19801"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57328"/>
            <dbReference type="ChEBI" id="CHEBI:61723"/>
            <dbReference type="EC" id="2.7.7.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="6">Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 4/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homohexamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the bacterial CoaD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.3" evidence="6"/>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93683">
        <property type="protein sequence ID" value="PRC93683"/>
        <property type="gene ID" value="S2091_1684"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00241">
        <property type="reaction ID" value="UER00355"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004595">
        <property type="term" value="F:pantetheine-phosphate adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015937">
        <property type="term" value="P:coenzyme A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02163">
        <property type="entry name" value="PPAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00151">
        <property type="entry name" value="PPAT_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004821">
        <property type="entry name" value="Cyt_trans-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001980">
        <property type="entry name" value="PPAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21342:SF1">
        <property type="entry name" value="PTHR21342:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01467">
        <property type="entry name" value="CTP_transf_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01020">
        <property type="entry name" value="LPSBIOSNTHSS"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01510">
        <property type="entry name" value="coaD_prev_kdtB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00125">
        <property type="entry name" value="cyt_tran_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 6" id="KW-0173">Coenzyme A biosynthesis</keyword>
    <keyword evidence="1 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2 6 8" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="CTP_transf_like" evidence="7">
        <location>
            <begin position="5"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="9"/>
            <end position="10"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="9"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="17"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="41"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="73"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="87"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="88"/>
            <end position="90"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="98"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="123"/>
            <end position="129"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="6">
        <location>
            <position position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00029346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC93683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="170" mass="19068" checksum="D43D4EAAB43245CD" modified="2018-07-18" version="1">MVTAVYPGTFDPLTRGHEDLVRRASGLFDTLVVGVADSKNKKPFFSLDERLSIANEVLGHYPNVRVESFSGLLKDFVRKNDARVIVRGLRAVSDFEYEFQMAGMNRYLLPDVETLFLTPSDQYQFISGTIVREIAQFGGDVSKFVFPSVDRWLQEKVQAAQAAANLDKGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1K0</accession>
    <name>A0A2S9H1K0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Type III secretion protein, HrpO family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_1474</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FliQ/MopD/SpaQ family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93865">
        <property type="protein sequence ID" value="PRC93865"/>
        <property type="gene ID" value="S2091_1474"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002191">
        <property type="entry name" value="Bac_export_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006306">
        <property type="entry name" value="T3SS_HrpO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34040">
        <property type="entry name" value="PTHR34040"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01313">
        <property type="entry name" value="Bac_export_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004669">
        <property type="entry name" value="FliQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00952">
        <property type="entry name" value="TYPE3IMQPROT"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01403">
        <property type="entry name" value="fliQ_rel_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="47"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC93865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="84" mass="9348" checksum="34CCE96D43101AD5" modified="2018-07-18" version="1">MDDIVYAGNKTLYLVLKLVLWPVIVATVVGLLVGLFQTVTQLQEQTLPFGIKLLAVSFCLFMLSGWYGEVLLNFGREVMRLALG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1N2</accession>
    <name>A0A2S9H1N2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="10">ATPase FliI/YscN family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">S2091_1469</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93860">
        <property type="protein sequence ID" value="PRC93860"/>
        <property type="gene ID" value="S2091_1469"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045261">
        <property type="term" value="C:proton-transporting ATP synthase complex, catalytic core F(1)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030257">
        <property type="term" value="C:type III protein secretion system complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030254">
        <property type="term" value="P:protein secretion by the type III secretion system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020003">
        <property type="entry name" value="ATPase_a/bsu_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000194">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_nucl-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005714">
        <property type="entry name" value="ATPase_T3SS_FliI/YscN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040627">
        <property type="entry name" value="T3SS_ATPase_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00006">
        <property type="entry name" value="ATP-synt_ab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18269">
        <property type="entry name" value="T3SS_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01026">
        <property type="entry name" value="fliI_yscN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00152">
        <property type="entry name" value="ATPASE_ALPHA_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0139">CF(1)</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="AAA" evidence="9">
        <location>
            <begin position="154"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC93860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="432" mass="47277" checksum="B9F56AA483AEABD2" modified="2018-07-18" version="1">MTQPLRLLRQLVHPHYLSGPIIEAPLRDVAVGEVCDVRRHWRDEDVVARAQVVGFRRDMAVLSLLGNPRGLSRESVLVPTGGALRICIDDSMLGAVLDSNGVHIARLAPALPVIHPQRWCALDAPPPSFDRRMPISEVFHSGIRVMDALTTCGVGQRLGIFASAGTGKTSFVTMLMEHASADVYVVGLIGERGREVTEFVEEMKKSPQRQRSVVVHATSDASSIDRCNAALLATTVAEYYRDHGCKVVLIQDSLTRYARALRDVALAAGEAPARRGYPASVFEALPRLLERPGVTDCGSITAFYTVLLESDDEVDPIAEEIRSILDGHIYLSRTLAAKNHYPAVDVLRSLSRVASRVCSPEQLQAAGRIREKLSRLDELQLMLDLGEYRPGESDLNDGLLQQKDALMEWMQQSRNSACDAGAIVAQMVALAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1P3</accession>
    <name>A0A2S9H1P3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Type III secretion apparatus protein, YscQ/HrcQ family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_1472</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FliN/MopA/SpaO family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93863">
        <property type="protein sequence ID" value="PRC93863"/>
        <property type="gene ID" value="S2091_1472"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030254">
        <property type="term" value="P:protein secretion by the type III secretion system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.330.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001543">
        <property type="entry name" value="FliN-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036429">
        <property type="entry name" value="SpoA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003283">
        <property type="entry name" value="T3SS_OMP_SpaO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013385">
        <property type="entry name" value="T3SS_SpaO/YscQ/SpaO"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01052">
        <property type="entry name" value="FliMN_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01339">
        <property type="entry name" value="TYPE3OMOPROT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101801">
        <property type="entry name" value="SSF101801"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02551">
        <property type="entry name" value="SpaO_YscQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0843">Virulence</keyword>
    <feature type="domain" description="FliMN_C" evidence="3">
        <location>
            <begin position="247"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC93863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="326" mass="35541" checksum="56A716CEB786592F" modified="2018-07-18" version="1">MKYPSLRHVVDAECHARAALALWPRRDAALIGRLAYAPLPNGPSVYAVQAYRKDRCWRGYVDLAEWLANTAPELASLACAADASTEHVRHLFAASAHPVDMPLPELGYDMLQIEHNPEQSLAQSKLCLLSILTPQGRVWLSEFPQPIAPVVGAVSASMQALPLLLAWHLGSSSASRRLVADLRRGDVLLIGCEAFELTSAGRVIGRFSINEDGEISVQATTMNELKEATTQDHVEAHTAPTVAITMGDIPLRLDFILQRRTMTVAQLDALYRGQVLSLDPQAEQQVEITVNGMRLATGELVELNGRLGIELHDIAVGTSLAEAHRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1U6</accession>
    <name>A0A2S9H1U6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Molybdopterin-binding domain of aldehyde dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1111</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC93938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93938">
        <property type="protein sequence ID" value="PRC93938"/>
        <property type="gene ID" value="S2091_1111"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036856">
        <property type="entry name" value="Ald_Oxase/Xan_DH_a/b_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016208">
        <property type="entry name" value="Ald_Oxase/xanthine_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008274">
        <property type="entry name" value="AldOxase/xan_DH_Mopterin-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037165">
        <property type="entry name" value="AldOxase/xan_DH_Mopterin-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11908">
        <property type="entry name" value="PTHR11908"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02738">
        <property type="entry name" value="Ald_Xan_dh_C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54665">
        <property type="entry name" value="SSF54665"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56003">
        <property type="entry name" value="SSF56003"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ald_Xan_dh_C2" evidence="1">
        <location>
            <begin position="264"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="domain" description="Ald_Xan_dh_C2" evidence="1">
        <location>
            <begin position="730"/>
            <end position="881"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="942" mass="103169" checksum="09FAE7E5B3269962" modified="2018-07-18" version="1">MIKLDLSRRSFLKVSVVAGVSVYVAPIGGKAFAALFEEKILSPIKWDGSSGQAKFRIDGIAKVTGAKVFARDIRSRDMPHWPTQQSHALILRTTKADRNYQGFNLNLLGAELQPDRIVTAEDLLRDGLAFPAFYGEDMLLPAGKIPAYLGHAVAILIYHDFAKFRFAKDLLQFKDEVIQYGPVSAPLERDPWGSFRFVRVGGATPFDDDVFSSLKNAPLFPSMMRKHQPVWPDGQEHGKLGEQGMFYAAQIQQQLDQPPADWLVMERDYNTQSVDTSALEPDNANCWYDSVNQELHMVVPTQSPAEVVDSTIEMLKKGKFPLKKLFLHPCYTVGYGSKDHYNFPFYGLLTALYADGKPVRLANDRFEQFQTSIKRHAFKMHYRMAVDRKSGLLQSFKGDFEANGGGRANFSPSVAMVGATAAQSIYYFPKNDLAAVAIATRAIDAGSARGYGTLQSMAATEMMVDEIAEKLGLDAIDFRLKNALRSGMKNTQGAIPAGAIRVDEVLQKAKLHPLWINRAKQKMTYEAAHPGMRYGVGFACVQKDFGTGAESSFAKVEISADGHIQLHHSGVEIGTGMSTSQAIACAKWLGKPADEVQTAITDWADLPVTASGDPYIMSQAEQDKLAMNPRWSPAYASPSSATNSAFYFTHSTREAARVIFLHGLWPAALSIWSQGIGGGQAAPLVVRVEDARWVDGKLSAAGLEALPYAQLVKKAHELGLVTGATVHVFNRWQWSEAEFEVSGNVVRLPLDGLSLRYGDGASPVQKKRMTTDGGYEVLNRKKVFIPPTQRNNAAVTYYSAVGTLVELAIHAASGKVELLTHHSIMECGNQLSPQLVSSQLQGGLAMGIGHALHEYLPLYEDGPGNGTWNFNRYQLPRAADVAVWTQTSEVLPPLTETDPAKGIAEVVMIPVVGAIVNGIAHAIGHRFTDLPVTQQQLQEILA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1Y1</accession>
    <name>A0A2S9H1Y1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1155</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC93982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93982">
        <property type="protein sequence ID" value="PRC93982"/>
        <property type="gene ID" value="S2091_1155"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003346">
        <property type="entry name" value="Transposase_20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002525">
        <property type="entry name" value="Transposase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01548">
        <property type="entry name" value="DEDD_Tnp_IS110"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02371">
        <property type="entry name" value="Transposase_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DEDD_Tnp_IS110" evidence="2">
        <location>
            <begin position="1"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="290" mass="31749" checksum="3B414B2B81A8E3F4" modified="2018-07-18" version="1">MEGTGTYGAGLARVLREQGVEVLEINRPNHSQRRLNGKSDPTDAENAARSVLSGEATSIPKSQSGAAEAMRTISIARRSAVKAKTQTINQLRSILVSAPQEIRERLWKIKAEQCVAGCAQLRQLGTTTLLKTLTTTLRLLAKRWLMLAAELKELDAALKQLTMQSAPHLREQFGIGPQTAATLIAVAGDNPERLRSEAALAALCGANPLPASSGKTVRHRLNRGGDRQANNALWTIAMVRMRSEPRTRAYVERRTAEGMSNKEIHRCLKRYIIRELYPLILADLAAATIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H239</accession>
    <name>A0A2S9H239_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative amidotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1225</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94052">
        <property type="protein sequence ID" value="PRC94052"/>
        <property type="gene ID" value="S2091_1225"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002818">
        <property type="entry name" value="DJ-1/PfpI"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01965">
        <property type="entry name" value="DJ-1_PfpI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015560787" evidence="1">
        <location>
            <begin position="31"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="domain" description="DJ-1_PfpI" evidence="2">
        <location>
            <begin position="33"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="336" mass="36015" checksum="CE2489E6D91EC296" modified="2018-07-18" version="1">MNTLYRYLLRLFTLATILFGAIATTNAAGAAPKRVAILLFEGVDVIDYAGPLEVFDTDGMQIFTVAATKATINPSDAMKVVPSYTFANAPQADILIVPGGQIDKVQSDPATLAWIKKQSAHATYVMSVCNGAFTLANTGLLSGLKVTTTAGRIDELRKKHPELQVVRDQRVVDNGKFIETGGLTAGIDGALHLVSLIAGDGEAHAIAQQMEYKWLPEGAYLPGTDAFHIVKEIMGIGMMSAHETGSMDGIASSSGDSTQWEIGYRLRSEKTDSDILKHVVQSYTGMALDSGGSAAVTTGVWQYRDAEGNQWNVKFNVDSVPGQTGMHVFKIEAVRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H264</accession>
    <name>A0A2S9H264_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Heavy metal response regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_1247</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94074">
        <property type="protein sequence ID" value="PRC94074"/>
        <property type="gene ID" value="S2091_1247"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006291">
        <property type="entry name" value="PcoR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01387">
        <property type="entry name" value="cztR_silR_copR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="3">
        <location>
            <begin position="2"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="4">
        <location>
            <begin position="127"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="2">
        <location>
            <begin position="127"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC94074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="227" mass="25838" checksum="F9DA67ED4695935A" modified="2018-07-18" version="1">MRILVIEDEIKTGDYLHNGLTESGYVVDIATNGSDGLHMAQEFHYDLIILDVMMPIMDGWEVMRRLQVDNKQPETPVLFLTARGTLEDRLKGLNLGADDYLVKPFSFAELLARVKIVLRRGAQVPQSEVLNIADLQIDIPARKVTRANSRIALTNKEFSLLQFFMQNQGQVLSRSLIASRVWDMNFDSDTNVVDVAVRRLRKKIDDPFEVQLIHTVHGVGYRCEVEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2B1</accession>
    <name>A0A2S9H2B1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cation/multidrug efflux pump</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1273</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94100">
        <property type="protein sequence ID" value="PRC94100"/>
        <property type="gene ID" value="S2091_1273"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2090.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027463">
        <property type="entry name" value="AcrB_DN_DC_subdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001036">
        <property type="entry name" value="Acrflvin-R"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32063">
        <property type="entry name" value="PTHR32063"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00873">
        <property type="entry name" value="ACR_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00702">
        <property type="entry name" value="ACRIFLAVINRP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82714">
        <property type="entry name" value="SSF82714"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="336"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="360"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="431"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="463"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="529"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="858"/>
            <end position="875"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="895"/>
            <end position="921"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="955"/>
            <end position="974"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="986"/>
            <end position="1012"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="1036" mass="113095" checksum="D8AB2A429AF54F8F" modified="2018-07-18" version="1">MNISAPFIQRPIATSLVMAAIFLIGLVAFPLLPVAPLPQVDFPTILVSTSLPGANSETMASSVATPLENQFAQIPGVAQMTSTSVLGSTQVTIQFDLDRNIDAAAQDIQSAINVASGFLPKNLPSPPIYRKINPAESSIIVFAVHSDSLPLTRVDDFAENVILPRISQISGVGLVSIGGQQKPAVRVQVDPAKIAAMGIQLSDLASVITTASVNGPKGGINGTKHNFVIYDNDQLLKAAPWNDVIVAYKNGAPVRIRDIGVAVDGPENNQMLAWQNGKNGILLLVYKQPGANIIDVVSRVNKALPQVLASVPSSIKIDKIIDRTTTIKAAVDDVEFTLLLTIILVVIVIFIFLRNIWATIIPSVTIPLALLGTFALMYWLGYTLDNLSLMGLTIAVGFVVDDAIVMLENIYRHIENGLSPLEAAYKGADEIGFTILSISISLVAVFIPLLLMGGIIGRLFREFAIVVTLTIAVSAFVSLTLTPMMCSRFIRDEKHAKHGRFYMLTERFFDWMLAGYTRGLDFVLRHQGITLITFFLTLATTVGLYVIEPKGFFPQQDTGIIIGLSDAAQDVSFDEMVRLQHKLTDIIAKDPDVESWATSVGGSRPLNNGFVVIGLKPLEQRHATSDQIIARLRSQFPTVPGATFFLQSAQDLNVGGRLSRTQYQYTLLDPDLNEINEWAPKLLAKLKALPQLRDVATDQQTDSTMLSVTIDRDQAARFGIQPADIDQTLYNAFGQNQVTQYFTQLNTYHVILEISPELQRDPDTLRKLYIKSPLTGQQVPLSTFVKYDTEHVAFLSINHQAQFPAVTLSFNLSAGVALGEAVEAIQKEVVDIKMPQAVVGTFQGTAQAFQTSLKSQPYLIAAALVAVYIILGILYESYIHPLTILSTLPSAGVGALLMLLAFHFELSVIALIGIILLIGIVKKNGIMMVDFAIQAEREQHLPPEESIRQACLLRFRPIMMTTMAALLAALPLMLGHGTGSELRQPLGYTMVGGLVLSQALTLFTTPVIYLYLDRFSLWLNRRRKRKAPLASSTLSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2D1</accession>
    <name>A0A2S9H2D1_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 8">Elongation factor G</fullName>
            <shortName evidence="8">EF-G</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">fusA</name>
        <name evidence="10" type="ORF">S2091_1318</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7 8">Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94145">
        <property type="protein sequence ID" value="PRC94145"/>
        <property type="gene ID" value="S2091_1318"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd16262">
        <property type="entry name" value="EFG_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01434">
        <property type="entry name" value="EFG_mtEFG1_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03713">
        <property type="entry name" value="EFG_mtEFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00054_B">
        <property type="entry name" value="EF_G_EF_2_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041095">
        <property type="entry name" value="EFG_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009022">
        <property type="entry name" value="EFG_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035649">
        <property type="entry name" value="EFG_V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000640">
        <property type="entry name" value="EFG_V-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004540">
        <property type="entry name" value="Transl_elong_EFG/EF2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005517">
        <property type="entry name" value="Transl_elong_EFG/EF2_IV"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00679">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14492">
        <property type="entry name" value="EFG_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03764">
        <property type="entry name" value="EFG_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00838">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00889">
        <property type="entry name" value="EFG_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="SSF54980"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00484">
        <property type="entry name" value="EF-G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 8 10" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="6 8" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="9">
        <location>
            <begin position="8"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="17"/>
            <end position="24"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="88"/>
            <end position="92"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="142"/>
            <end position="145"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00017872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC94145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="701" mass="77884" checksum="B13E74FB6C7C8528" modified="2018-07-18" version="1">MARKTPIERYRNIGISAHIDAGKTTTTERVLFYTGVNHKIGEVHDGAATMDWMEQEQERGITITSAATTCFWKGMANNFPEHHINIIDTPGHVDFTIEVERSMRVLDGACMVYCAVGGVQPQSETVWRQANKYKVPRLAFVNKMDRTGANFFKVYEQMRARLKANPVLIQIPIGAEENFLGVVDLVKMKAIYWDEASQGMKFDYREIPAELQEQAAEWREKMVEVAAEYTEELMNKYLEEGDLSEEEIKAALRARTIAAEIVPMMCGTAFKNKGVQAMLDAVIEYLPSPVDIPPVTGLDEDDEPTSRKAEDTEKFSALAFKIMTDPFVGQLIFFRVYSGMVKSGDTVFNPNKNKKERLGRILQMHANQREEIKEVHAGDIAAAVGLKEATTGETLCDPSSIITLERMVFPEPVISQAVEPKTKVDQEKMGLALNRLAQEDPSFRVKTDEESGQTIIGGMGELHLEIIVDRMRREFGVEATVGKPQVAYRETIRKTCEEIEGKFVKQSGGRGQYGHVVLKIEPQEAGKGFEFVDAIKGGTVPREYIPAVEKGVRETLTSGVMAGYPVVDVKVTLFFGSYHDVDSNENAFRMAGSMAFKDGCRKASPVILEPMMSVEVETPEDYAGTVMGDLSSRRGMVQGMDEIPGGGGKIIKAEVPLSEMFGYSTSLRSATQGRATYTMEFKHYSEAPKNVIDAIVTAKAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2I8</accession>
    <name>A0A2S9H2I8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_1351</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94178">
        <property type="protein sequence ID" value="PRC94178"/>
        <property type="gene ID" value="S2091_1351"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="5"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="5">
        <location>
            <begin position="132"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="132"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC94178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="237" mass="27030" checksum="259CCB38F243495B" modified="2018-07-18" version="1">MDTNQILIVDDDREIRTLLADYLQTNGYRCFMAAEGNAMWHTLNEHDVDLVVLDLNMPGEDGLTLCRNLRAKSSLPVIMLTARSEPLDRILGLEMGADDYLPKPFEPRELLARIRSVLRRSSGQSQSTNDKIQFLRFAGWTLDLTARHLLDPKEMVVLLSGAEFRMLKIFLEHPNRVLNRDQLLNMTQGRDADPFDRSIDIQISRIRQKLGEDARSPQIIKTVRNGGYVLAVNVETV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2J0</accession>
    <name>A0A2S9H2J0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0826</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94205">
        <property type="protein sequence ID" value="PRC94205"/>
        <property type="gene ID" value="S2091_0826"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="238" mass="27180" checksum="7174D7D60E15FEFB" modified="2018-07-18" version="1">MNILDSVNYQLVSPKNFSAEQKQFVNKFKETTCLISSQADMILGAKDIHSRHFISTDAYAKLVALPNGYEITDRFDRDMPCEGTAQFADCFIEEDNALLNSGDLHQKKSTLNVHEYSGGIQALVFNKHILKHLPSQSILGTVYSAHEIEITNFFKLMPNYIEEFGIGCSIENVTGTLSVGDKLLTDYEHEVCFLIMMNWDFKQIANFMNKHRPKPRLRVADTIHKCKNRICYKLGLFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2Q5</accession>
    <name>A0A2S9H2Q5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">HipA-like N-terminal domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0882</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94261">
        <property type="protein sequence ID" value="PRC94261"/>
        <property type="gene ID" value="S2091_0882"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012893">
        <property type="entry name" value="HipA-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07804">
        <property type="entry name" value="HipA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HipA_C" evidence="2">
        <location>
            <begin position="67"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="312" mass="35399" checksum="4A6AA5BE35A4C3FA" modified="2018-07-18" version="1">MPRRFNHAVILSFINLFTIQFIFGNESYARYLSDIAKVLELLIPDVERAVRYPEMAEHAMQGESPGSSAGGEQPKFTAVIQRSGEHELFEHVIVKFSPKVDTLNGRRWGDLLICEHLALEVLARNQIAAAKTSLIEAGGRVFLEVVRFDRVGLRGRRPMATFSALDGDLGMLDQNWTTVSRELGRLGHLSEKDIETVEILDLYGTLIGNTDKHHGNIALAWTFNGRHQLLDVYDMLPMLYRPNAHGEIVEREWVPNLGARLELIHLQRCYEMANQFWTDVLNDPRISREFKQGIADRHLNTMRALNVGATNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2T0</accession>
    <name>A0A2S9H2T0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">2Fe-2S iron-sulfur cluster binding domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_0899</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94278">
        <property type="protein sequence ID" value="PRC94278"/>
        <property type="gene ID" value="S2091_0899"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00207">
        <property type="entry name" value="fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006058">
        <property type="entry name" value="2Fe2S_fd_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008333">
        <property type="entry name" value="Cbr1-like_FAD-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00970">
        <property type="entry name" value="FAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00111">
        <property type="entry name" value="Fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="SSF52343"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="SSF54292"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="SSF63380"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00197">
        <property type="entry name" value="2FE2S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding FR-type" evidence="6">
        <location>
            <begin position="26"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="5">
        <location>
            <begin position="294"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC94278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="383" mass="41831" checksum="2E8A4470C5B26DF6" modified="2018-07-18" version="1">MCAVTALTRSNTSSVSKFFIERAIVPQFFPLTISHVQHEPGDALVLTLAVPADLREHFTYIQGQHLTLRAYIDGKETRRAYSLCNAVGEPSLQLAIKKVAGGAFSNWAHQTLQRGTQIDVMQPAGHFNTTLDAKHARHYAGFVAGSGITPLLSIIKTSLQQEPDSRFTLVYCNRTLSSMLFREQLADLKDRFPQRLSLIYLFTAEAQEIELLNGRLSTERCRALLQHWLPSASIDYAFVCGPAAMMQAVAAALSEAGLPDERIKLEYFAAAGSTITPDSAPAQTESLTTLTSAVEMTLIVDGVQRQLRLDKAVDNILDAALEAGIDLPYSCKGGVCATCRCKVLQGEVAMTGNYALSANELAAGYVLSCRSRPLTRRLVLDFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H330</accession>
    <name>A0A2S9H330_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">3-oxoacyl-(Acyl-carrier-protein) synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_1010</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94389">
        <property type="protein sequence ID" value="PRC94389"/>
        <property type="gene ID" value="S2091_1010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd00834">
        <property type="entry name" value="KAS_I_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000794">
        <property type="entry name" value="Beta-ketoacyl_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11712">
        <property type="entry name" value="PTHR11712"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PKS_KS" evidence="3">
        <location>
            <begin position="23"/>
            <end position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC94389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="446" mass="48741" checksum="459B632A3320EC92" modified="2018-07-18" version="1">MPAQMYSTLKRELHTMAYDNSPICISAIGAVTPLGDTLDEVTSAFYEGRSGIRKIEKFSTDTFDTKWAGLPPIANDLMHWPDRENRYSPRPGEVLYAERAIQSLLAEFNPLDVYAADRVGCVLGVDEPAINPQRCIDIVQRTGRDNINNRREMINKAVQSFRISELLDIDTTAVLRTIHKAIPFSGYTRTHVGLCSASLQALGMAFNAIREGRIDAAIVGGVSAKVTPMNIARLEAIGAVCTDAALEGTERSRPFDRRRSGFMPAEGSVLFVIEREDAVRARGGQIYARLKGYGASLSAEHIVAPHTQNTEMRLCMQRALADAGIPLDEFSAINTHGTSTKLNDHHESRAIAEVFEGFKIPAVAATKSQHGHLIASAGAMEVLGVIGSFRDDFLPAIRNLGESDEEAILPLLRKRRDGPVRNVLKNSFGMGGLASSMVLQNPRLVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H336</accession>
    <name>A0A2S9H336_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0988</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94367">
        <property type="protein sequence ID" value="PRC94367"/>
        <property type="gene ID" value="S2091_0988"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="51"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="298" mass="32683" checksum="3AFBFCE828C0D28C" modified="2018-07-18" version="1">MTTHHSSVTGKEVTVMKSKPLTIIVIVVALFAGAAMWIYFSWNKEAGPASTQVTADQSNPEKSTGHQWFSNITNTSKPDGSKTKLSIFKGGDGKYVDVNGTTVTQYVNGLRAAADKGDTLAEYNIYSAETYCTGVVKRQRVYNTQPTDTEQAFCKDFNFSPKERLDYLNMAAKGGNNMALVTFGTEAPEWLSQDPESGVKDPRYTAWTQQAFNYNQQAAQQGSSIAMFMLGDSYARGLGVQQNYQLAVTYDLAFRALSYTNKDLTTIPPNPNYAEQLTPDEIAQARSAAAALIKSIPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H374</accession>
    <name>A0A2S9H374_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Pyridoxal phosphate homeostasis protein</fullName>
            <shortName evidence="1">PLP homeostasis protein</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_1056</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94435">
        <property type="protein sequence ID" value="PRC94435"/>
        <property type="gene ID" value="S2091_1056"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02087">
        <property type="entry name" value="PLP_homeostasis"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001608">
        <property type="entry name" value="Ala_racemase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029066">
        <property type="entry name" value="PLP-binding_barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011078">
        <property type="entry name" value="PyrdxlP_homeostasis"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10146">
        <property type="entry name" value="PTHR10146"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01168">
        <property type="entry name" value="Ala_racemase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004848">
        <property type="entry name" value="YBL036c_PLPDEIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51419">
        <property type="entry name" value="SSF51419"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00044">
        <property type="entry name" value="TIGR00044"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ala_racemase_N" evidence="4">
        <location>
            <begin position="45"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="1 2">
        <location>
            <position position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR004848-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC94435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="275" mass="31165" checksum="C18E3A141A17E16E" modified="2018-07-18" version="1">MMTSISCIGEITATVLSETNSDRQDQAHYPQANNIEDFRHNLACVNERITRACRRVDRNPSNVRLLPVSKTFDEASLRLAYTADCRLFGENKVQEASRKWESMTDLTDLNWALIGHLQTNKVKQVARFASEFHALDSLHIAEELDRRLQVEGRYLDVYVQVNTSGEASKYGLPPNEVISFLNSLPSYNSLRVRGLMTLAIFSSDEVRVRSCFAQLRELRDQARQDVHTCIELEELSMGMSSDAEIAIEEGATIVRIGQAIFGARSLPNAYYWPRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H394</accession>
    <name>A0A2S9H394_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Glycerol-3-phosphate dehydrogenase [NAD(P)+]</fullName>
            <ecNumber evidence="8">1.1.1.94</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">NAD(P)H-dependent glycerol-3-phosphate dehydrogenase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">gpsA</name>
        <name evidence="17" type="ORF">S2091_1073</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>NAD(+) + sn-glycerol 3-phosphate = dihydroxyacetone phosphate + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:11092"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57597"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.94"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 13">
            <text>NADP(+) + sn-glycerol 3-phosphate = dihydroxyacetone phosphate + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:11096"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57597"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.94"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="8 14">Membrane lipid metabolism; glycerophospholipid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8 14">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 8 12">Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.94" evidence="8"/>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94452">
        <property type="protein sequence ID" value="PRC94452"/>
        <property type="gene ID" value="S2091_1073"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00940"/>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009331">
        <property type="term" value="C:glycerol-3-phosphate dehydrogenase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004367">
        <property type="term" value="F:glycerol-3-phosphate dehydrogenase [NAD+] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046167">
        <property type="term" value="P:glycerol-3-phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046168">
        <property type="term" value="P:glycerol-3-phosphate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006650">
        <property type="term" value="P:glycerophospholipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00394">
        <property type="entry name" value="NAD_Glyc3P_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006168">
        <property type="entry name" value="G3P_DH_NAD-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006109">
        <property type="entry name" value="G3P_DH_NAD-dep_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011128">
        <property type="entry name" value="G3P_DH_NAD-dep_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07479">
        <property type="entry name" value="NAD_Gly3P_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01210">
        <property type="entry name" value="NAD_Gly3P_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000114">
        <property type="entry name" value="Glycerol-3-P_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00077">
        <property type="entry name" value="GPDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00957">
        <property type="entry name" value="NAD_G3PDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 8" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="5 8" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="4 8 11" id="KW-0520">NAD</keyword>
    <keyword evidence="3 8 12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6 8 14" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="7 8" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD_Gly3P_dh_N" evidence="15">
        <location>
            <begin position="2"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="domain" description="NAD_Gly3P_dh_C" evidence="16">
        <location>
            <begin position="175"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="8 10">
        <location>
            <begin position="250"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8 9">
        <location>
            <position position="186"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8 11">
        <location>
            <begin position="7"/>
            <end position="12"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 10">
        <location>
            <position position="102"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8 11">
        <location>
            <position position="135"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 11">
        <location>
            <position position="250"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="276"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000114-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000114-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000114-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU004280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF01210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF07479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="PRC94452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="328" mass="34180" checksum="CCD5677AC803D64B" modified="2018-07-18" version="1">MKITILGAGAWGSALAIALAPRHQVILWGRNSEVIQQADQTRQHQGFTLPPSLQLSADFNQALAHVNQSDSLLIVATSVAGLRPLSQALKAHSVPNLIWLCKGLEEGSLLLPHQVVQQELGDTLPCGALSGPSFAQEVALGKPCALTIASNFPVLSDLVVSALHSSAMRVYSSDDVVGVEVGGAVKNILAIATGVADGLGLGLNARAALITRGLAEITRLGQALGGKLETFMGLTGMGDLILTCTGDLSRNRRVGLALAQGKPLAQIVQELGHVAEGVRCAQAVQSLSRQYGVDMPITDAVAGVLFDGDSTADMVRRLLARDAKAELN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3D8</accession>
    <name>A0A2S9H3D8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">LysM domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1101</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94480">
        <property type="protein sequence ID" value="PRC94480"/>
        <property type="gene ID" value="S2091_1101"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00118">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036779">
        <property type="entry name" value="LysM_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01476">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54106">
        <property type="entry name" value="SSF54106"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51782">
        <property type="entry name" value="LYSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015454816" evidence="1">
        <location>
            <begin position="20"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="2">
        <location>
            <begin position="38"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="362" mass="39713" checksum="BC6EC6F57E65D613" modified="2018-07-18" version="1">MKKFSTIALLLALSSSVFAADEMNAPQTQCAFLPNAPDQHLVVKGDTLWGISQMFLEHAWCWPQVWGMNREDIKNPHWIYPGQIVYFDRAAGRLRLGQPAGGGGSDTSPGNIPTVRLSPQIRGENLASNAITTIPSNVIEPFLSQPLILEENELKDTPRIVSAQQGHVNAGKSEKVYAMGDLHGGSFFQVYRPSTPLKDPETNKIIGYESAYLGTLKLTREGKTDNEAHTFLVTTSKEEMTVGDRLLPVPNSEMANYVPHPPSADVNARIVSIYGGVAQAGQNQTISINRGSKDGIDIGTVLQLYRLGDIIADKTKSKSVIKLPDEQYGTLFIYRVFKNISYGLIMQVTDSAQVGDIVRKPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3F6</accession>
    <name>A0A2S9H3F6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Addiction module toxin, RelE/StbE family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0518</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94515">
        <property type="protein sequence ID" value="PRC94515"/>
        <property type="gene ID" value="S2091_0518"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2310.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007712">
        <property type="entry name" value="RelE/ParE_toxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035093">
        <property type="entry name" value="RelE/ParE_toxin_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004386">
        <property type="entry name" value="Toxin_YafQ-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40588">
        <property type="entry name" value="PTHR40588"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15738">
        <property type="entry name" value="YafQ_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006156">
        <property type="entry name" value="YafQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143011">
        <property type="entry name" value="SSF143011"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02385">
        <property type="entry name" value="RelE_StbE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-1277">Toxin-antitoxin system</keyword>
    <feature type="active site" description="Proton donor" evidence="2">
        <location>
            <position position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR006156-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="104" mass="11993" checksum="2CDB0199409B98B7" modified="2018-07-18" version="1">MTLKKTAASKRAPLPRGSDYTKAFIKDWERLSHSGRYDMKRLKEAMLLLIDNDVPLGAEWHDHPLKGEWSDYRECHIGGDFLLIYECDGNIINFVRAGTHAELF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3K3</accession>
    <name>A0A2S9H3K3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0516</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94513">
        <property type="protein sequence ID" value="PRC94513"/>
        <property type="gene ID" value="S2091_0516"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015673983" evidence="1">
        <location>
            <begin position="33"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="300" mass="32453" checksum="B1037238DF455509" modified="2018-07-18" version="1">MKSKSKPLATITISATLLAVLIVGAGSYWSNAAPTSPTSVQVALQTSPEKPKGQQWFSVSKGSPPVANRESRFMDADGAIVDLNGLTVSQYVNTLYDAANKGDKKAAYNIYKAESICESITPMQQNMREMSAANDPNFFTSIEASINDVQAICADLNSGTRERLNYLLIAAKGGVAPAAIAYAFEPPEGFDAFHIKDIDLADPRVIQWQQDAVRYLTQSATQGNVATLNLLSGFYANGQMAPKNLQLALTYEIASLELRNENLKNEFITKLSDQLTLIQVNAATTSANQLVNSCCNKHAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3L4</accession>
    <name>A0A2S9H3L4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Rhodanese-like domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1077</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94456">
        <property type="protein sequence ID" value="PRC94456"/>
        <property type="gene ID" value="S2091_1077"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="SSF52821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="26"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodanese" evidence="2">
        <location>
            <begin position="61"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="151" mass="16421" checksum="BD9A759513931858" modified="2018-07-18" version="1">MFGHLFYNDAVNLDYWICVKFIIDNIWLIGLILISGGALLVPVLQRRGAKVSLLQATQLMNQSKCVVLDVREAAEFEAGHIKSAKNIPLSDLSKRLGELEKQKSHAVITVCAKGTRSATAAAMLNRAAFTNVVSLDGGMAAWQEQGLPVVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3U1</accession>
    <name>A0A2S9H3U1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0657</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94654">
        <property type="protein sequence ID" value="PRC94654"/>
        <property type="gene ID" value="S2091_0657"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="53" mass="6017" checksum="5C83D11C0E8E627C" modified="2018-07-18" version="1">MPAISVGKSTNKLRYISGLLPFTAHFKINTINETQAFWPLIDLVSKDNNLELR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3Z2</accession>
    <name>A0A2S9H3Z2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0707</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94704">
        <property type="protein sequence ID" value="PRC94704"/>
        <property type="gene ID" value="S2091_0707"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="238" mass="26553" checksum="B7694AE2B34F2A51" modified="2018-07-18" version="1">MTIAELPFRATTEQACDWLTQQTGMPWTLTSLIENGLTPYVWLDYDANYPELFGEANGGYPAPIFFEGDTQRLAAGSEDVLITITKDVYTIVTQLKPPGFRRALHELRFLKKDLERLANKLKREAQPQLQPVNIKEATESQKGINKEQVLMAFSSLVKIDLEQALDSGGGIFGDDGARVKGSAKKGKNKTVWNPITLALGLNDVYRVPMSRLTRAFNAHDFLDAWAADWNHTLALLGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H495</accession>
    <name>A0A2S9H495_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Arginine and ornithine succinyltransferase subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0007</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94812">
        <property type="protein sequence ID" value="PRC94812"/>
        <property type="gene ID" value="S2091_0007"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008791">
        <property type="term" value="F:arginine N-succinyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006527">
        <property type="term" value="P:arginine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007041">
        <property type="entry name" value="Arg_succinylTrfase_AstA/AruG"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04958">
        <property type="entry name" value="AstA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03243">
        <property type="entry name" value="arg_catab_AOST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="349" mass="38130" checksum="CBC5F8CE58665DF2" modified="2018-07-18" version="1">MFIVRPVATSDIPALIELAAGLTQGVHTMAKTPAAIERAVEQSLRSFASQTDIAGEECYLFVLEDLENTSSHSLIGSAAISATAGSKGTFFSFRNDVIQQVSRDLDISHSVHALTLCADLTSYSQLSSFFVRRGNHIHPEAALLSRARLMFAACAPERFSDNFFVSLAGYTDQKGCAPFWEALGKKFFQMDFLEAERLVDGARNRNLIVELMPHYPVYVPLLTGDAQAAMGQVHPESEVPFDLLTKEGFAADDFIDIFDGGPILEANKHALSSFAHGLKLQVETVSDDSAPISTNANRSYLVATARETDFRATMMQSTALENTQTVRLSSEVMQALNVIDGDHVLCVPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4B9</accession>
    <name>A0A2S9H4B9_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">Malonyl CoA-acyl carrier protein transacylase</fullName>
            <ecNumber evidence="2 5">2.3.1.39</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_0729</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>holo-[ACP] + malonyl-CoA = CoA + malonyl-[ACP]</text>
            <dbReference type="Rhea" id="RHEA:41792"/>
            <dbReference type="Rhea" id="RHEA-COMP:9623"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57384"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78449"/>
            <dbReference type="EC" id="2.3.1.39"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the fabD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.39" evidence="2 5"/>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94726">
        <property type="protein sequence ID" value="PRC94726"/>
        <property type="gene ID" value="S2091_0729"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004314">
        <property type="term" value="F:[acyl-carrier-protein] S-malonyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014043">
        <property type="entry name" value="Acyl_transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024925">
        <property type="entry name" value="Malonyl_CoA-ACP_transAc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016036">
        <property type="entry name" value="Malonyl_transacylase_ACP-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00698">
        <property type="entry name" value="Acyl_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000446">
        <property type="entry name" value="Mct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00827">
        <property type="entry name" value="PKS_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="SSF52151"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55048">
        <property type="entry name" value="SSF55048"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PKS_AT" evidence="7">
        <location>
            <begin position="6"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="86"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR000446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000446-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC94726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="311" mass="33568" checksum="78514BB40CFC3730" modified="2018-07-18" version="1">MSLLFMYPGQGAQRTGMLHKLPDTIEVDDTLSQSSEILGYDCQLLDSATALESTHSVQLCLLIVGVAMTRVFAANGIVPNMVVGLSIGAFPAAVAAGVLTFSDAIRLVQLRSRLMENAYPVGFGMAAINGLDKFELERIIEKFHSSSTPVYLANLNAQKKLVVSGLKLTLDKVMQQALHSGASNALHLAVNVPSHCPLFETAAKQMQTSIDSILLQRPGLKYLSANAARSLFDPQLIGIDLAANMARQVHWFETLRLAQELGAQLAFEMPTGTVLTELATAQWSDGTALACDTSRLDTLIALAKRLQSREQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4F8</accession>
    <name>A0A2S9H4F8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0018</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94823">
        <property type="protein sequence ID" value="PRC94823"/>
        <property type="gene ID" value="S2091_0018"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="62"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="89"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="173"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="200" mass="22219" checksum="1388161F95680454" modified="2018-07-18" version="1">MGLENLTGKLMKSLITPFVPSKIGSIVLDAPKKAISDSIAAKIKLEATMRAYQILAGAHRSLINTILWQNALLLFSILPVYFLHSAIPFYIAYACVATYTTITFAQSWPQLMNCLKTRSLLIPIKSAVLQAIKAELCQLQFVERKVVEYLGPDLEELSSDIARQLLPDIRSALINMGLTLIMAFVAFRLTAIPMLEHRAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4K6</accession>
    <name>A0A2S9H4K6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="12">TonB family C-terminal domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">S2091_0001</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
            <orientation evidence="1">Periplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TonB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94806">
        <property type="protein sequence ID" value="PRC94806"/>
        <property type="gene ID" value="S2091_0001"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006260">
        <property type="entry name" value="TonB/TolA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037682">
        <property type="entry name" value="TonB_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03544">
        <property type="entry name" value="TonB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01352">
        <property type="entry name" value="tonB_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015407229" evidence="10">
        <location>
            <begin position="26"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_C" evidence="11">
        <location>
            <begin position="178"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="33"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF03544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PRC94806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="256" mass="26763" checksum="8EAAFB87B0937AF6" modified="2018-07-18" version="1">MVQIKKCSALSFLAFSQIMTLLLCVACSKDPSPDTDSASANAPEAGAPTTPRTTGLVKNPIKLSDTADAVKWMDMASTKSPAQIAKEEKLAKDAADAKLAAETKKVHDDKLAADAKLAADAKIAADAKLAADAKALAAAKALEKQKIAAAVQSPPAAPPKAAPVVAQEPILNVITGEQPKFPSRAVRDGVTKGIVTAQLHVETDGRVSKVEIVNATPKKYFDKAVISAALQWKYAPISKPLTTTMEFEFKMAGDGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4K8</accession>
    <name>A0A2S9H4K8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">YceI-like domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0115</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94920">
        <property type="protein sequence ID" value="PRC94920"/>
        <property type="gene ID" value="S2091_0115"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007372">
        <property type="entry name" value="Lipid/polyisoprenoid-bd_YceI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036761">
        <property type="entry name" value="TTHA0802/YceI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04264">
        <property type="entry name" value="YceI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101874">
        <property type="entry name" value="SSF101874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015678343" evidence="1">
        <location>
            <begin position="24"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="domain" description="YceI" evidence="2">
        <location>
            <begin position="57"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="243" mass="26305" checksum="1554B587E928652B" modified="2018-07-18" version="1">MHIKKPGLVLLCCTFAIFLLSCANPQHISSTPETPVASSNITSTYTKLTQTGGTLFRLNPAASTVRIYAFRGGLAGKLGHNHVLSAPQFTGFFYAPASGLAQSQFDLEFRLDQLQLDNPEQRAALGPAFASVLDEDAIASTRSHMLGDSNLQADKYPLLRIHSLQITGEAPKFAAKIQIELHGQLREMWVPLSVQGLPEKLLVTGALVVKQTDFGITPYSALGGLLAVQDELLIEFQLCSANR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4L1</accession>
    <name>A0A2S9H4L1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0120</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94925">
        <property type="protein sequence ID" value="PRC94925"/>
        <property type="gene ID" value="S2091_0120"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="88" mass="10082" checksum="2CADD8383643C6FE" modified="2018-07-18" version="1">MSRTRHAKKEVEDALRYAEIHGWRISIGGSHAWGKMVCPYNDKDCRCGEFCISSIWSTPKNPGNHARQIKRVVDNCTGKNTRDDSFKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4R7</accession>
    <name>A0A2S9H4R7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="9">ABC-type sugar transport systems ATPase component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_0170</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94975">
        <property type="protein sequence ID" value="PRC94975"/>
        <property type="gene ID" value="S2091_0170"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008643">
        <property type="term" value="P:carbohydrate transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03301">
        <property type="entry name" value="ABC_MalK_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015855">
        <property type="entry name" value="ABC_transpr_MalK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008995">
        <property type="entry name" value="Mo/tungstate-bd_C_term_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040582">
        <property type="entry name" value="OB_MalK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17912">
        <property type="entry name" value="OB_MalK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50331">
        <property type="entry name" value="SSF50331"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="5" id="KW-1278">Translocase</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="8">
        <location>
            <begin position="4"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="37"/>
            <end position="44"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC94975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="377" mass="41584" checksum="651C90AFB5DDC068" modified="2018-07-18" version="1">MASLSIRNVRKVYPNGAEILKGIDLEIEDGQFLILVGGSGCGKSTLLNMIAGLETVSDGSIHIGDRCVNDIPPKSRDIAMVFQSYALYPTMTVRENISFGLGIRKVPKDEQKKIVDRVAETLQMTHLLDRKPALLSGGQRQRVAMGRAIARNPALFLFDEPLSNLDAKLRVEMRAEIKLMHQRLGTTIVYVTHDQIEAMTLGDKIAVMKDGVVQQFGSPQDIYDEPANMFVAGFIGSPSMNFLRGKLLKQDGGLSFTLEHKGKTTLLPLPASFSTTLIPMGQIERDIILGIRPEHITDAISARRAETTDSYQPTEVECTVELTEPTGPDTLVFSWFNQARATCRTHPRAAATPGEQMKLAFDLSKAVLFDPTTEQRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H506</accession>
    <name>A0A2S9H506_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Efflux transporter, RND family, MFP subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_0243</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95048">
        <property type="protein sequence ID" value="PRC95048"/>
        <property type="gene ID" value="S2091_0243"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006143">
        <property type="entry name" value="RND_pump_MFP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01730">
        <property type="entry name" value="RND_mfp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="domain" description="HlyD_D23" evidence="4">
        <location>
            <begin position="91"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="123"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC95048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="397" mass="43017" checksum="0B297C77366E3524" modified="2018-07-18" version="1">MRPEPGQLPTSLPSPHRIQWRWIVAGAVLIAVIVGIWLFRHSTAETELPKPADKKEAVVFELADTDVATIAARELHVNLPISGSLIPQNNITVKSKVTAVVSETTVQEGDSVIEGQVLARFDNADLSARLETQEAAVEESNTKLVLAKKNRESSYALFKQNYISQNAFDTSENALELAQANLKSTISQREVARLALADTVVHAPMQGVISKRLVQAGEKVSPDTPLFSLVNLTKLNLEAQVPASEIPRVKIGQTVSFSVDGFAGREFVGNVVRINPNVENGTRSFMVYVEVNNRDGALRGGMFAKGQLSLQKTSKTSIVPLIAVHQLNGVTTVYKIEQNRVVAQTVKLGLRNDDEGYAEVKDGLTVGEQVIISQLNMVKPGSKVSLPEHKASSGSKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H562</accession>
    <name>A0A2S9H562_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Microcystin-dependent protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0201</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95006">
        <property type="protein sequence ID" value="PRC95006"/>
        <property type="gene ID" value="S2091_0201"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1340.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011083">
        <property type="entry name" value="Phage_tail_collar_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037053">
        <property type="entry name" value="Phage_tail_collar_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07484">
        <property type="entry name" value="Collar"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Collar" evidence="1">
        <location>
            <begin position="7"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC95006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="178" mass="18606" checksum="3914A0CDC6E5EC2D" modified="2018-07-18" version="1">MADSFIGEIRIFAGNYAPVDWLFCDGSLLNITEYQTLYALIGTAYGGNGNTTFALPNLNGKLPVGQGSGPNLTPRTIAQTFGVTTVSLTSNQLPSHLHTIQASNNPATTITPGPTLALGTIASPSVFYDLGNSVPANQRAFNSQAFSLSGGSTPHENTMPTLSLSYIISTAGMYPSQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5F9</accession>
    <name>A0A2S9H5F9_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Phospho-N-acetylmuramoyl-pentapeptide-transferase</fullName>
            <ecNumber evidence="9">2.7.8.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">UDP-MurNAc-pentapeptide phosphotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">mraY</name>
        <name evidence="10" type="ORF">S2091_0402</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>di-trans,octa-cis-undecaprenyl phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine = di-trans-octa-cis-undecaprenyl diphospho-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine + UMP</text>
            <dbReference type="Rhea" id="RHEA:28386"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="ChEBI" id="CHEBI:60392"/>
            <dbReference type="ChEBI" id="CHEBI:61386"/>
            <dbReference type="ChEBI" id="CHEBI:61387"/>
            <dbReference type="EC" id="2.7.8.13"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="9">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the glycosyltransferase 4 family. MraY subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.13" evidence="9"/>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95207">
        <property type="protein sequence ID" value="PRC95207"/>
        <property type="gene ID" value="S2091_0402"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008963">
        <property type="term" value="F:phospho-N-acetylmuramoyl-pentapeptide-transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051992">
        <property type="term" value="F:UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine:undecaprenyl-phosphate transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06852">
        <property type="entry name" value="GT_MraY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00038">
        <property type="entry name" value="MraY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000715">
        <property type="entry name" value="Glycosyl_transferase_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003524">
        <property type="entry name" value="PNAcMuramoyl-5peptid_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018480">
        <property type="entry name" value="PNAcMuramoyl-5peptid_Trfase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22926">
        <property type="entry name" value="PTHR22926"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00953">
        <property type="entry name" value="Glycos_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10555">
        <property type="entry name" value="MraY_sig1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00445">
        <property type="entry name" value="mraY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01347">
        <property type="entry name" value="MRAY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01348">
        <property type="entry name" value="MRAY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3 9" id="KW-0132">Cell division</keyword>
    <keyword evidence="9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9" id="KW-0133">Cell shape</keyword>
    <keyword evidence="9" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="22"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="66"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="97"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="134"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="190"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="222"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="262"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="286"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="313"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="367"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC95207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="389" mass="42577" checksum="B4C21B0255752A5B" modified="2018-07-18" version="1">MLLWLAQYFQQDMGVLRVFNFITFRAVFATLTSITIGLLAGPGVIRMLTRLKVGQAVRTDGPQTHLIKSGTPTMGGVLLLISIGISTLLWADLSNRFVWVVLVVTLGFGAIGWVDDYRKVVFKDPKGMASKEKYFWQSLIGIVAAVYLAFSVSAPSNGQFFDIFINWVQSGFTMDLPNKADLIVPFFKTISYPLGVWGFIALTYFVIVGTSNAVNLTDGLDGLAIMPTVMVGSALGLFAYVTGNASYSKYLLLPHIPGAGELLIFCGAMAGAGLAFLWFNAHPAQVFMGDVGALALGGALGTIAVIVRQEIVLFMMGGVFVVETISVILQVGYFKFTKKKFGTGKRLFLMAPLHHHFEQKGWKETQVVVRFWIITMMLVLLGLSTLKLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5G0</accession>
    <name>A0A2S9H5G0_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF1653 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0420</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95225">
        <property type="protein sequence ID" value="PRC95225"/>
        <property type="gene ID" value="S2091_0420"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.320">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023387">
        <property type="entry name" value="DUF1653-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037135">
        <property type="entry name" value="DUF1653-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07866">
        <property type="entry name" value="DUF1653"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF1653" evidence="1">
        <location>
            <begin position="5"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC95225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="66" mass="7728" checksum="A36A9A55508D8839" modified="2018-07-18" version="1">MNMKKYKHYKGGIYEFICSATLESDPSIQMIVYRAANGTIWTRPENVFFEEIEHQGQKIPRFALIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5J7</accession>
    <name>A0A2S9H5J7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0442</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95247">
        <property type="protein sequence ID" value="PRC95247"/>
        <property type="gene ID" value="S2091_0442"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002818">
        <property type="entry name" value="DJ-1/PfpI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01965">
        <property type="entry name" value="DJ-1_PfpI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="1">
        <location>
            <begin position="224"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC95247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="325" mass="34805" checksum="A0215CDDEB4C73DC" modified="2018-07-18" version="1">MIDFTVLVLPGSFASSVALTLDILSAAASLAERVGCAKPRWCVYSAEGGDVQLSNGLKIEAKALPKTIRSDGSVWVIPGLGVDNPRAIMQLFTQPEVLLAMKALQGHARAGGTVAASCSAVFLLQSTGLLVGRKVTTSWWLAPLLQRMEPRCMVDADRMVISDGAVVTAGAAFAQTDLMLHLLRTRFSPALSDAVSRALLIDGRQSQAQFIAPAMFADGNELIARLVTRFELSLPNPPSVSVLAAEFSMSDRTLSRHVRAATGRSTSALLQSVRLSKARVLLETSKLTVEQVAERVGYADTTALRRLMRKAMGATPRQFRPAVSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5N9</accession>
    <name>A0A2S9H5N9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Helix-turn-helix domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0463</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95268">
        <property type="protein sequence ID" value="PRC95268"/>
        <property type="gene ID" value="S2091_0463"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001845">
        <property type="entry name" value="HTH_ArsR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00418">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50987">
        <property type="entry name" value="HTH_ARSR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH arsR-type" evidence="1">
        <location>
            <begin position="12"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC95268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="241" mass="26626" checksum="E86C7D61E9CEF6DA" modified="2018-07-18" version="1">MNALTTSDMQDINHVDIHLSQIAAAIAEPARAKMLCCLLDGRARTSTELAVVGEISPSTASSHLAKLKEQYLVTVLAQGKHRYYQLAGKEVADAMEALLRIAGVAQARFIPNTPTKLRNARSCYDHMAGSVAVELHDYFKNQGWLTAISDDGTNYDLHPDGIAALEHIGLDVTSVRQTRRRFACACLDWSERKPHIAGALGNALLKFMLNRAWLERELDGRALIISKEGQRQFKKLFAIDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSH0</accession>
    <name>A0A2S9GSH0_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NfeD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_4619</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000039">
        <property type="protein sequence ID" value="PRC90669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90669">
        <property type="protein sequence ID" value="PRC90669"/>
        <property type="gene ID" value="S2091_4619"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002810">
        <property type="entry name" value="NfeD-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01957">
        <property type="entry name" value="NfeD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="domain" description="NfeD" evidence="2">
        <location>
            <begin position="52"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC90669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="145" mass="15974" checksum="45F3F23C8AF91379" modified="2018-07-18" version="1">MSDWMSWLVVAGIAVMIELYTGTFYLLMIAIGMAAGALAAFLGVGKEFQLIIAAIVGVLATVTLRRSRFGLRNKVSASRDPNVNLDIGQLIQINEWQSIAPDLHTARAMYRGALWDVEFFGHAEPKSGMFKIVEIRGSQLVVEMQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSY2</accession>
    <name>A0A2S9GSY2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein kinase domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_4492</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000035">
        <property type="protein sequence ID" value="PRC90829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90829">
        <property type="protein sequence ID" value="PRC90829"/>
        <property type="gene ID" value="S2091_4492"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031634">
        <property type="entry name" value="PknG_rubred"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031636">
        <property type="entry name" value="PknG_TPR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16919">
        <property type="entry name" value="PknG_rubred"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16918">
        <property type="entry name" value="PknG_TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="171"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="75"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC90829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="750" mass="81770" checksum="3F87C084967888FD" modified="2018-07-18" version="1">MADYIADGIAVTCAYCGGQIVDDVCEDCGKSAKKKPLVTANAGGLDVPDSVAIAETTTGRTRSSTAQFKVNYPTRATGKNTGKSTRRRVGASTHTSTRRAALGGGLISLPDLPSQDPLKLLMIMPEVPANKRHCPKCDIQVNRSKGFCPSCGTPYDFVPHLKAGDIVAGKYEIKGPVAFGGLGWIYLGFDRVLQRWVVLKGLLNASDEASAAAAVAERRYLAAVKHPKIVGIYDFVNEGAEGYIIMEYVGGQTVHSLRKQRGPLPVEEAIAYILGIIPAFSYLHGQGLVYCDFKPDNAMLEGGDIKLIDMGAVRKINDPDGDIYATVGFAAPEADNEPTAVSDLYTLGRALAVLIMDFKFTKEYEHSLPTPDQHDVLAANESLYRFLLRATHSDPDERFQSADEMGEQLFGVLREIVSLQSGPKPADSKVFTGDRLIKGEAQALITAPAPLFLPALRVNLEDRAANEVIRILSLMDAAQQVSELQSLVEKYGDRATEPRLRLVEVLIQSEDVLPQERQTIIEKALAEVEAADAFDWRVGWYRGIWLLMQGNGAQAISQFERCYFEMPGELGPRLAMGIAAEMDGNMELALSYYDRVGQVDPSFVSAHAGAARCHAKAARLNEALAMLQRVPTAHAMRVQAQLAIGELVLTYPDYIDGTTMKQSEAAVQSVLDNGGSAFQIAGRLCALAVHLNQKISWPKNATFLGFEFSENSLRLGAEKQFRLAAKQAESEIDRFYWVSQANSVRPVTLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GT35</accession>
    <name>A0A2S9GT35_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4437</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000034">
        <property type="protein sequence ID" value="PRC90856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90856">
        <property type="protein sequence ID" value="PRC90856"/>
        <property type="gene ID" value="S2091_4437"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC90856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="63" mass="7257" checksum="7178B9DB4160887F" modified="2018-07-18" version="1">MSIKVTYSLYTSIEIIFDDTLKAYVLSIDICNEYVEKCKFHRHIIVSVLNTSGHLHSKLLAQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GT64</accession>
    <name>A0A2S9GT64_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative addiction module antidote protein, CC2985 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000033">
        <property type="protein sequence ID" value="PRC90907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90907">
        <property type="protein sequence ID" value="PRC90907"/>
        <property type="gene ID" value="S2091_4400"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.10.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022789">
        <property type="entry name" value="ParD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038296">
        <property type="entry name" value="ParD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010985">
        <property type="entry name" value="Ribbon_hlx_hlx"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36582">
        <property type="entry name" value="PTHR36582"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03693">
        <property type="entry name" value="ParD_antitoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47598">
        <property type="entry name" value="SSF47598"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02606">
        <property type="entry name" value="antidote_CC2985"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-1277">Toxin-antitoxin system</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="85" mass="10027" checksum="B92C48AC2A94070B" modified="2018-07-18" version="1">MQSMNISLPDPLKKFVDDQIAEGRYSSVSEYMRELIRDDEKRKAEDRLEVLLLEGLSSEETELTREDWNIIRKEALARINKKKQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GT87</accession>
    <name>A0A2S9GT87_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Thioredoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_4326</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000032">
        <property type="protein sequence ID" value="PRC90925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90925">
        <property type="protein sequence ID" value="PRC90925"/>
        <property type="gene ID" value="S2091_4326"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015036">
        <property type="term" value="F:disulfide oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015760322" evidence="4">
        <location>
            <begin position="22"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="5">
        <location>
            <begin position="20"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC90925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="126" mass="14110" checksum="A567550008920AF4" modified="2018-07-18" version="1">MFIRFITAMIFSVIFCGAALAAGKPYDAATFDALKNEGKPIMVLVSAPWCPYCKRQDEVVNTLLKDPRFQTLNVVDVDFDTHQDFLKTWHVPIQSTIIMIKGGKVISQNAFDIHADSIEAMMLKAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTG7</accession>
    <name>A0A2S9GTG7_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Succinate--CoA ligase [ADP-forming] subunit alpha</fullName>
            <ecNumber evidence="2">6.2.1.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Succinyl-CoA synthetase subunit alpha</fullName>
            <shortName evidence="2">SCS-alpha</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">sucD</name>
        <name evidence="7" type="ORF">S2091_4301</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 5">Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 5">
            <text>ATP + CoA + succinate = ADP + phosphate + succinyl-CoA</text>
            <dbReference type="Rhea" id="RHEA:17661"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57292"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.2.1.5"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 5">Carbohydrate metabolism; tricarboxylic acid cycle; succinate from succinyl-CoA (ligase route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2 5">Heterotetramer of two alpha and two beta subunits.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the succinate/malate CoA ligase alpha subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.2.1.5" evidence="2"/>
    <dbReference type="EMBL" id="PUGF01000031">
        <property type="protein sequence ID" value="PRC91005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91005">
        <property type="protein sequence ID" value="PRC91005"/>
        <property type="gene ID" value="S2091_4301"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00223">
        <property type="reaction ID" value="UER00999"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004775">
        <property type="term" value="F:succinate-CoA ligase (ADP-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.261">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01988">
        <property type="entry name" value="Succ_CoA_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017440">
        <property type="entry name" value="Cit_synth/succinyl-CoA_lig_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033847">
        <property type="entry name" value="Citrt_syn/SCS-alpha_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003781">
        <property type="entry name" value="CoA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005810">
        <property type="entry name" value="CoA_lig_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005811">
        <property type="entry name" value="CoA_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016102">
        <property type="entry name" value="Succinyl-CoA_synth-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02629">
        <property type="entry name" value="CoA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00549">
        <property type="entry name" value="Ligase_CoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001553">
        <property type="entry name" value="SucCS_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00881">
        <property type="entry name" value="CoA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52210">
        <property type="entry name" value="SSF52210"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01019">
        <property type="entry name" value="sucCoAalpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01216">
        <property type="entry name" value="SUCCINYL_COA_LIG_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00399">
        <property type="entry name" value="SUCCINYL_COA_LIG_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4 7" id="KW-0436">Ligase</keyword>
    <keyword evidence="1 2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="CoA_binding" evidence="6">
        <location>
            <begin position="4"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Coenzyme A binding" evidence="2">
        <location>
            <begin position="17"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Coenzyme A binding" evidence="2">
        <location>
            <begin position="99"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="active site" description="Tele-phosphohistidine intermediate" evidence="2 3">
        <location>
            <position position="252"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="46"/>
        </location>
        <ligand>
            <name>CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="164"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared with subunit beta</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR001553-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC91005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="293" mass="30522" checksum="201D5F4E14618775" modified="2018-07-18" version="1">MSILINKDTKVITQGITGKTGQFHTRGCRDYANGKNCFVAGVNPKKAGEDFEGIPIFANVGEAKAATGATVSVIYVPPAGAAAAIWEAVEADLDLAICITEGIPVRDMMMLKDRMAKAGSKTLLLGPNCPGLITPDEIKIGIMPGHIHRKGRIGVVSRSGTLTYEAVGQLTALGLGQSTAVGIGGDPINGLKHIDIMKAFNDDPDTDAVIMIGEIGGPDEANAAYWIRDNMKKPVVCFIAGVTAPPGKRMGHAGALISGGADTAQAKLDIMAECGIKATKNPSEMARLLKAML</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTQ9</accession>
    <name>A0A2S9GTQ9_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 4">Guanine deaminase</fullName>
            <shortName evidence="4">Guanase</shortName>
            <ecNumber evidence="3 4">3.5.4.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Guanine aminohydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_4203</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>guanine + H(+) + H2O = NH4(+) + xanthine</text>
            <dbReference type="Rhea" id="RHEA:14665"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16235"/>
            <dbReference type="ChEBI" id="CHEBI:17712"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="EC" id="3.5.4.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="4">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 4">Purine metabolism; guanine degradation; xanthine from guanine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.3" evidence="3 4"/>
    <dbReference type="EMBL" id="PUGF01000029">
        <property type="protein sequence ID" value="PRC91107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91107">
        <property type="protein sequence ID" value="PRC91107"/>
        <property type="gene ID" value="S2091_4203"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00603">
        <property type="reaction ID" value="UER00660"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008892">
        <property type="term" value="F:guanine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006147">
        <property type="term" value="P:guanine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01303">
        <property type="entry name" value="GDEase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014311">
        <property type="entry name" value="Guanine_deaminase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11271:SF6">
        <property type="entry name" value="PTHR11271:SF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="SSF51338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02967">
        <property type="entry name" value="guan_deamin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Amidohydro-rel" evidence="5">
        <location>
            <begin position="78"/>
            <end position="417"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU366009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC91107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="447" mass="49551" checksum="7F0AD6D8F0CE2D06" modified="2018-07-18" version="1">MHSAVGNTNAGKNVTQAYRASILYFTNDPAFDSQATVWHEDGVLIACDGKVQAVGAYAQLKNTLAEDVVIQDYRGKLLMPGFIDTHLHYPQTDMIASPADGLLPWLDKYTFPTERQFSDAQHAQEVARFFLDELLRCGTTSAMVYCSVHPESVDAFFTESAARNLRMVAGKVMMDRNCPEFLQDSAEQSARDSEALINKWHKNGRQLYAITPRFAATSTDAQLKLAGELARTYPDTYLQTHVAENVDEVAWIKSLFPKARSYLDVYDYYGMLRPRSMYGHCIWLDEFDRSRMAQTQSAIAICPTSNLFLGSGLFNFDYADAQQVLMSLASDVGAGTSFCMLKTMNEAYKVARLGGTHLSALRMFYLATLGAARCMQLEGVIGSFEIGAEADFIVLDLQATPLLARRTACTTSLEELLFVLAMLGDDRAIWATYAAGCLVHTRVSSDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTU5</accession>
    <name>A0A2S9GTU5_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 11">Cysteine synthase</fullName>
            <ecNumber evidence="5 11">2.5.1.47</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">S2091_4124</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>hydrogen sulfide + O-acetyl-L-serine = acetate + L-cysteine</text>
            <dbReference type="Rhea" id="RHEA:14829"/>
            <dbReference type="ChEBI" id="CHEBI:29919"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:58340"/>
            <dbReference type="EC" id="2.5.1.47"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 9 11">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid biosynthesis; L-cysteine biosynthesis; L-cysteine from L-serine: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 11">Belongs to the cysteine synthase/cystathionine beta-synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.47" evidence="5 11"/>
    <dbReference type="EMBL" id="PUGF01000028">
        <property type="protein sequence ID" value="PRC91123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91123">
        <property type="protein sequence ID" value="PRC91123"/>
        <property type="gene ID" value="S2091_4124"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00136">
        <property type="reaction ID" value="UER00200"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004124">
        <property type="term" value="F:cysteine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006535">
        <property type="term" value="P:cysteine biosynthetic process from serine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005856">
        <property type="entry name" value="Cys_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005859">
        <property type="entry name" value="CysK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001216">
        <property type="entry name" value="P-phosphate_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="PLP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="Trypto_synt_PLP_dependent"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="SSF53686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01139">
        <property type="entry name" value="cysK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01136">
        <property type="entry name" value="cysKM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00901">
        <property type="entry name" value="CYS_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="8 11" id="KW-0198">Cysteine biosynthesis</keyword>
    <keyword evidence="7 9 11" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PALP" evidence="12">
        <location>
            <begin position="10"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="region of interest" description="Pyridoxal phosphate binding" evidence="9">
        <location>
            <begin position="180"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="75"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="275"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="10">
        <location>
            <position position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR605856-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR605856-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PRC91123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="325" mass="33986" checksum="B1FCFB9B384FFF86" modified="2018-07-18" version="1">MSNWFKDNSLSIGRTPLVRLNHVSDGAGATILAKIEGRNPAYSVKCRIGAAMIDDAEKRGVLGPGKELVEPTSGNTGIALAFVAAARGIPLTLTMPETMSIERRKLLLAYGAKLILTEGAKGMSGAIAKAEEIAASNPDKYVLLQQFKNPSNPAIHEATTGPEIWNDTDGKVDIFIAGVGTGGTITGVSRYLKKIKGAKVQSVAVEPIASPVLSQARAHETIKPGPHKIQGIGAGFVPEVLDLSLVDDIETVSNEDAIAFALRLAREEGILSGISSGAATAVAVRLAKLPQNAGKTIVVILPDSGERYLSSVLFDGVFDVSGLKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GU40</accession>
    <name>A0A2S9GU40_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">MltA-interacting protein MipA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_4013</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MipA/OmpV family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000026">
        <property type="protein sequence ID" value="PRC91228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91228">
        <property type="protein sequence ID" value="PRC91228"/>
        <property type="gene ID" value="S2091_4013"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010583">
        <property type="entry name" value="MipA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38776">
        <property type="entry name" value="PTHR38776"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06629">
        <property type="entry name" value="MipA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015716893" evidence="5">
        <location>
            <begin position="19"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC91228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="264" mass="28970" checksum="A107526A6C6D1B63" modified="2018-07-18" version="1">MKKILPLLLMALALNAQAQTADFVEIIPTQYLQKDLTASVGLGIASLPKYADGSKQEILPLPVFNLQWKSGVFFSSVSGFGYNFSANPNWQYGMRLGLLAYQEQSARNRDNGPGNTPTSLTPGVFANYLIDQHFSILTSLSSGAGINNKHNGNFASIGGRYIDRIDDKNRIFAVLSTTWANGQYMQDFYGVTPQQASTYNFPVYDTNAGMLKVKLSLGWDYTINKNWSMIVGGSVTHPLGDAGSSPLVSDKNQVVVYSAAYYRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GU47</accession>
    <name>A0A2S9GU47_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_4018</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="PUGF01000026">
        <property type="protein sequence ID" value="PRC91233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91233">
        <property type="protein sequence ID" value="PRC91233"/>
        <property type="gene ID" value="S2091_4018"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="158"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="8">
        <location>
            <begin position="182"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="7">
        <location>
            <begin position="290"/>
            <end position="521"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC91233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="537" mass="60010" checksum="4C0A8392E42F14A6" modified="2018-07-18" version="1">MLKKNAFPFYFRLAFFLRGTSLRSAIIAAVFFGLIGSAIILIPYNISSIDTNAHKRQLEDHQRLTNILAVIQSEPLWQITPDIARISSDVVYSDPRIATIDVFSLPDHKKFLTLSRKEQQKGPFSTIVHTIKHDEKVIGIVELTMADDLLIEEERTAFIRYAITAIFSLIIAVILILLVLQQRLVVPIRRLMKESERLSNGELTNPIVFNRSDEIGHLADTMEATRQALARTFSELEIKNNQLTDYSNTLESKVKLRTSELETALKNINHVHQELTRIERMASLGSMVAGVAHELNTPIGNCLLVASTLEAEVLKFTELFTVGNVRRSELDKFMQCANESSTLLLRGLHQAAHLVGDFKQVAVDQSSAQRRQFDLHTMMIELTSLLMPGLSKTPYILIIDIPTNIEMDSFPGPLGQVFTNLITNSVTHGFNERDYGNMRITAELVGHNVKMTFTDDGYGIPPEILHRIYEPFFTTRFGRGGSGLGLSITYNIVTNVLGGEILATSAQNQGCKFVITLPLVTPIMDEANAPSTLNFAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GU74</accession>
    <name>A0A2S9GU74_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Dolichyl-phosphate-mannose-protein mannosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4044</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000026">
        <property type="protein sequence ID" value="PRC91259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91259">
        <property type="protein sequence ID" value="PRC91259"/>
        <property type="gene ID" value="S2091_4044"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="78"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="123"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="160"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="210"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="269"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="300"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="336"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="365"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="403"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="429"/>
            <end position="450"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="686" mass="76064" checksum="5E876F91AE5BEC44" modified="2018-07-18" version="1">MKKLLSAINKLDSRMVFFSTLVLIFFYLLFRNTGLYTMVQSDEWAYSSFSRLIPFNEAQLPSYLYFSIFHLTNYCGDGFLACARALNVLLFLAAAPFIYLVARNYMSGKLSGFIAIMSVCGPLNTYTAYFMPEATYFLAFWVITWAAFQFRAAPTSKRCAVLGITIALASMIKIHALFLLPALLLFILYTAYATYSGNGNSTWLRTGLRLISIALASAALVRFGIGALYAGKNGLDLLGTLYRNQAAGTAHPTMQHLLELTLVSASGHAMGLIVLFGVPLAATLVYPMNRTESKSTTTALLLYLLLMLGSLLAITVMFTATVVGLYDSITRLHMRYYDFIIPLFLIFAGSQLSRNSSEPPIIKKLIIGTMIAIAIIYSRYFLLEQFSPSIIDCPDLNGLSIKHIFNQFTVLAVFCIAAWITNNKLGIKLFLYVFMPIYTILTSIAIAHTFRSSMAPDIYERAGIYVHDHLSKDEIAKVIVIGADDAGLFKSKFHMDNPKVDLQSTPKGQPIDISRFAHDKHWLLIIGDYPSIPNVLSRQDSGDYSLLLIANEDGTIPPIDFSKPLAGGDLVHIKGLSNPESWGGSWSIDDNVELKFDTALPKKLTLHLTADAYGPNIGQNFVIMIGASRQTFNLTNEARELIFNMETDGAQHVITIEIPQPTSPKQLGISEDARRLGIAMIRMKIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUE8</accession>
    <name>A0A2S9GUE8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3902</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000024">
        <property type="protein sequence ID" value="PRC91357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91357">
        <property type="protein sequence ID" value="PRC91357"/>
        <property type="gene ID" value="S2091_3902"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="388"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="2">
        <location>
            <begin position="482"/>
            <end position="683"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="684" mass="75273" checksum="9B9399FD5B31CAD2" modified="2018-07-18" version="1">MLLTSFAPYRLRLLFRGAFLLLALATVALALSVLQQEKQLSYNNYQTSFKKSQQQISATLRHPVGQLALLNPPGDKKGTGLHPLLLPFSALDFDDQNKVQQAITMSGCLVQYGSSGSLCVGIGNNPWAGGFIYAAGNFNSATLVPHQRGDLMLNQSHRIKVSVTLRGQSYRWIAPFEVDAPNRMQGLRGRFTGFWEDDANKPNARPVKEFRGWVWQKAVCNQIELDDADAACKKNAFFSLRLPIAVLQDALFEKKRPVWPPEDLDQIQVQLSVLAPNSDEVLFDSSSVPTAAPFSLGELQSSLLPGETLRIRKLAGQNDLIKLAGIVDNADDSWNLLTRLIRRLPVGEFDQPLDSVEEISTPLGNYEVILQGDVRSVSKSLSVVASRISWYVGGMLLALLLAWLFIEIGIIHRITLLTKRASSLSKTVKGAGGLERFDVSDLRSSDELGILASCLHDLLRRVKEDVEREAIRAEQEKEMWHAVGHEIMSPLQSLMVLHGTNEDPSNRYINRMQQAIRVLYGSASPSEAFQSTVLQVTEIDITTFLKHVASNAPCVGITQVEFIGADLPVMVRADDYSLEDVVTHVLRNAERYRVAGSAITMSLITSETAASITIHNQGPQIALELIDKIFEYGVSDQHDSGANGNRGQGLFVAKTYMAKMGGTISVENVSDGVSFTLSLQRGVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUL3</accession>
    <name>A0A2S9GUL3_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CsbD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3832</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0337 (CsbD) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000023">
        <property type="protein sequence ID" value="PRC91417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91417">
        <property type="protein sequence ID" value="PRC91417"/>
        <property type="gene ID" value="S2091_3832"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008462">
        <property type="entry name" value="CsbD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036629">
        <property type="entry name" value="YjbJ_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05532">
        <property type="entry name" value="CsbD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69047">
        <property type="entry name" value="SSF69047"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CsbD" evidence="2">
        <location>
            <begin position="4"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="61" mass="6628" checksum="10459E7174ACFF3E" modified="2018-07-18" version="1">MNKDQTNGAAKNIGGKIQEQAGKLVGSQSQQVKGFKHQIDGKTQEIVGDLKEAYRASKIKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUL7</accession>
    <name>A0A2S9GUL7_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Dephospho-CoA kinase</fullName>
            <ecNumber evidence="2">2.7.1.24</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Dephosphocoenzyme A kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">coaE</name>
        <name evidence="3" type="ORF">S2091_3943</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>3'-dephospho-CoA + ATP = ADP + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18245"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57328"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.24"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 5/5.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the CoaE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.24" evidence="2"/>
    <dbReference type="EMBL" id="PUGF01000024">
        <property type="protein sequence ID" value="PRC91398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91398">
        <property type="protein sequence ID" value="PRC91398"/>
        <property type="gene ID" value="S2091_3943"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00241">
        <property type="reaction ID" value="UER00356"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004140">
        <property type="term" value="F:dephospho-CoA kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015937">
        <property type="term" value="P:coenzyme A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00376">
        <property type="entry name" value="Dephospho_CoA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001977">
        <property type="entry name" value="Depp_CoAkinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01121">
        <property type="entry name" value="CoaE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00152">
        <property type="entry name" value="TIGR00152"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51219">
        <property type="entry name" value="DPCK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0173">Coenzyme A biosynthesis</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 3" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="27"/>
            <end position="32"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="219" mass="23730" checksum="F24D47BB4AFFA4E6" modified="2018-07-18" version="1">MSSAVDQQKTTNIATGKFLIGLTGGIGSGKTSVANGFAERGASVIDTDAIAHSLTAPGGTAITAIQAAFGNDIISPQGAMDRAKMRALVFSDVRQKLRLEAILHPMIRAEVARQTKLATGPYIIYVVPLLVEKGHWKLARILVVDCDEELQMQRVMQRDGLSEQVVKAIMAQQATRTQRLAVATDVIQNQGAFEALIPEIDRLHQLYCQLSSANQTEYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUQ4</accession>
    <name>A0A2S9GUQ4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative conserved small protein containing a coiled-coil domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3880</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000023">
        <property type="protein sequence ID" value="PRC91465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91465">
        <property type="protein sequence ID" value="PRC91465"/>
        <property type="gene ID" value="S2091_3880"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007420">
        <property type="entry name" value="DUF465"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038444">
        <property type="entry name" value="DUF465_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04325">
        <property type="entry name" value="DUF465"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="66" mass="7671" checksum="C5C88ABA075A23F9" modified="2018-07-18" version="1">MSDHTEIQNRITILAVEHRDLDIVIEALILAGHTDELQLQRLKKRKLQLKDHIKLLQMQLIPDVPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUR8</accession>
    <name>A0A2S9GUR8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nucleoside-diphosphate-sugar epimerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3875</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000023">
        <property type="protein sequence ID" value="PRC91460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91460">
        <property type="protein sequence ID" value="PRC91460"/>
        <property type="gene ID" value="S2091_3875"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="1">
        <location>
            <begin position="20"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="311" mass="34044" checksum="719F18AC45C691A7" modified="2018-07-18" version="1">MLAVFLSNMSSALSKNKRAIVTGLNGFTGHYVEAELKAAGFDVYGIGEKESLSPHYTQVNLADRDGLHAAISHIKPHVVLHLAGVAFVGNANAESFYTVNTIGTRNLLEALVAQAPDVECVLLASSANIYGNATQGMLDESTLPNPANDYAVSKLAMEYMARLWLDKLPIIITRPFNYTGVGQTDSFLLPKIINHFKQGKQEIELGNCDVFRDFSDVRAVANAYRRLIEARPIGQIINVCSGKSHSLREVLAMAGKIAGYDISVKVNPAFVRANEVRTLLGSAERLRGIIGEWDSPPLHDTLEWMYRSSTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUV8</accession>
    <name>A0A2S9GUV8_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SnoaL-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3851</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000023">
        <property type="protein sequence ID" value="PRC91436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91436">
        <property type="protein sequence ID" value="PRC91436"/>
        <property type="gene ID" value="S2091_3851"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037401">
        <property type="entry name" value="SnoaL-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12680">
        <property type="entry name" value="SnoaL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015758990" description="SnoaL-like domain-containing protein" evidence="1">
        <location>
            <begin position="24"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="domain" description="SnoaL-like" evidence="2">
        <location>
            <begin position="37"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="155" mass="17290" checksum="13AA4E1878B98EBE" modified="2018-07-18" version="1">MKTAFNSIVFIFMVMSMTTASFSATTSISPEELVQLQLDAYNAHDMDAFLATYSDTAQIIEFPSTVQAVGKEQMRQRYATRFNDPTRHCTIVNRIVMGNTIVDHERIRATFPEGVGVLEAIAIYEVVDGKIVKATLKVGEKKLDTDVGLPRHSEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GV67</accession>
    <name>A0A2S9GV67_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Rhomboid family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_3716</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000021">
        <property type="protein sequence ID" value="PRC91600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91600">
        <property type="protein sequence ID" value="PRC91600"/>
        <property type="gene ID" value="S2091_3716"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022764">
        <property type="entry name" value="Peptidase_S54_rhomboid_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035952">
        <property type="entry name" value="Rhomboid-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01694">
        <property type="entry name" value="Rhomboid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144091">
        <property type="entry name" value="SSF144091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="151"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="181"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="209"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="234"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="272"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="domain" description="Rhomboid" evidence="6">
        <location>
            <begin position="142"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC91600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="488" mass="55499" checksum="DCDBD2365FEFFFB7" modified="2018-07-18" version="1">MFIIPVGDRVNWKRPPIITLLLILVNCYVFFALQGKDAQHEQQAGKYYFSSELPDWELPRYASYLEQQGRSDEFKKFNALLLKKNGMALPIMVHDTKFMLALQSEKIITPTAPEYTNWKTQHVHYMEQRSFTSRYIFEVDNPSLLKAFTSAFLHGGFDHLLGNMVVLFLVGFLVESMVGKIVFTLGYCISALVAAYSFGLLNAEVSQTLLGASGAIAGVMGMYTVIFGSRKIDFFYSLGFYFDYVRAPAIMLLPLWLGNELYQFFSANGSHVAYMAHFGGLLCGALIASLYRWQRPNQIKQQHQEAEKDEMDGAAFQRGMNYLGQMEFKKALSIFTELQAKHPKDVNLAKLVYRAAKADPASQEYHRAALRLLSLRAMDETTSHQTYTIFQEYLRCAKPSHRLGSDLVSKLAQRFASTGYVDDAEKLTAVLQRATPPHQELPTVLLALARGYYREQRKDQFNATLQRLIRQFPHSEEAQAANKILQMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVH2</accession>
    <name>A0A2S9GVH2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acetyltransferase (GNAT) domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3480</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000019">
        <property type="protein sequence ID" value="PRC91725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91725">
        <property type="protein sequence ID" value="PRC91725"/>
        <property type="gene ID" value="S2091_3480"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13673">
        <property type="entry name" value="Acetyltransf_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="138" mass="15791" checksum="FCA9C86C7DCED553" modified="2018-07-18" version="1">MNFEFKTQDVDWTVVASIFQQVGWGNRQPAEIRSAFEKSSYVIFAYDGAELVAFGRTMDDGQYYALLVDIVVKPDRQQSGLGREIVNYLKSQLVGYKFITLTAAPGKEEFYLKLGWQRQATALIWPVSEEQQRLHVTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVI8</accession>
    <name>A0A2S9GVI8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HpnE: squalene-associated FAD-dependent desaturase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3659</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000020">
        <property type="protein sequence ID" value="PRC91721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91721">
        <property type="protein sequence ID" value="PRC91721"/>
        <property type="gene ID" value="S2091_3659"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002937">
        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017830">
        <property type="entry name" value="SQase_HpnE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03467">
        <property type="entry name" value="HpnE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amino_oxidase" evidence="1">
        <location>
            <begin position="11"/>
            <end position="437"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="438" mass="47462" checksum="09728690F3CAD6FC" modified="2018-07-18" version="1">MKYAVIGAGWAGCSAAVELAKRGHQVHLFEAARTLGGRARQVSSHDLMLDNGQHILLGAYKATLALLSTLGINQKTTLLRLPLQMCYPPDSGGMEFIAPKLPAPWHVAVALLKASGLTRADKMALMRFSSTARWMGWQLNNDCSVAELLHRYDQTDNLTRLMWQPLCIAALNTPIHRASAQVFLNVLKDSLGAKRAASDMLIARTDLTSLLPQPAAQFIEAQGGQVHLGCAVHSIEKNTEWQLNFQQTQANFDGVVIATSAEVASNLLAPLNMAEHIPTFEYEPITTCYLKYATDIKLARPFLALVERPEHSAWGQFVFDRGQIEGEKAGGIAAQAGLFAVVVSTSQQAIEHGHAELAFNCAKQLAVDLMRPELAVPEWSQVITEKRATFACTPGLVRPANQLPVSGLVLAGDYTESSYPATLESAVQSGVLAANLLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVP4</accession>
    <name>A0A2S9GVP4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3552</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000019">
        <property type="protein sequence ID" value="PRC91797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91797">
        <property type="protein sequence ID" value="PRC91797"/>
        <property type="gene ID" value="S2091_3552"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001845">
        <property type="entry name" value="HTH_ArsR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00778">
        <property type="entry name" value="HTHARSR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00418">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50987">
        <property type="entry name" value="HTH_ARSR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH arsR-type" evidence="1">
        <location>
            <begin position="1"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="114" mass="12789" checksum="34BA836203A7EFCE" modified="2018-07-18" version="1">MENYSASLNNVFHALADPTRRSVIARLGNGSASIKELAEPFDLGLPSFLKHIKVLESSGLITSEKVGRVRTCKLKRGNLIAAEKWFDEQRAGWENRYENLDNLLITLKGEKDES</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVQ0</accession>
    <name>A0A2S9GVQ0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative transcription regulator contains HTH domain (MarR family)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3562</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000019">
        <property type="protein sequence ID" value="PRC91807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91807">
        <property type="protein sequence ID" value="PRC91807"/>
        <property type="gene ID" value="S2091_3562"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014601">
        <property type="entry name" value="Trans_reg_MarR_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13463">
        <property type="entry name" value="HTH_27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036158">
        <property type="entry name" value="UCP036158_MarR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="1">
        <location>
            <begin position="67"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="185" mass="20240" checksum="ACBFD37987EC99B1" modified="2018-07-18" version="1">MTKKSLNTSAISAPDNPQTRPVIVSSAHLAAGKSAELSEFEFGLIISGNAFNRWITRCMAAAGVSDMTTIEVLVLHHVNHRARSKKLADIAFLLNIEDTHVVNYALKKLQNLDLIATEKRGKEVLYSTNEKGQAVCAKYFEVREQVLVASLAGGAQESFELQELARFLRGLSGLYDQASRAATSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVR9</accession>
    <name>A0A2S9GVR9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phenazine biosynthesis protein, PhzF family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3375</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PhzF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000018">
        <property type="protein sequence ID" value="PRC91819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91819">
        <property type="protein sequence ID" value="PRC91819"/>
        <property type="gene ID" value="S2091_3375"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003719">
        <property type="entry name" value="Phenazine_PhzF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13774">
        <property type="entry name" value="PTHR13774"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02567">
        <property type="entry name" value="PhzC-PhzF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016184">
        <property type="entry name" value="PhzC_PhzF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00654">
        <property type="entry name" value="PhzF_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" evidence="2">
        <location>
            <position position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR016184-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="279" mass="29511" checksum="71667F91AF6EA557" modified="2018-07-18" version="1">MAHNILNIAAFSDGEQGGNPAGVWIGTELPDEATMQRIAHEVGFSETVFAASAGNGWRVRYFSPESEVPFCGHATIALGAALALAHGDGLFELTLNHANITVEGKRQGSLIAAALQSPTTHSEAVSDALLADALALFGLQHNDLDPRIAPAIIHGGAKHLVLSLKDRETLRAMHYDLDAGRRLMNGAGMATILLAFAETNQLFHTRNPFASGGVYEDPATGAATAAFAGYLRDIHWPHQGKINIIQGEDMGCRSLLQAEITSQIGASIRVSGSARIMAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVT1</accession>
    <name>A0A2S9GVT1_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Flagellar L-ring protein</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Basal body L-ring protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">flgH</name>
        <name evidence="6" type="ORF">S2091_3380</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 5">Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell outer membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Bacterial flagellum basal body</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the FlgH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000018">
        <property type="protein sequence ID" value="PRC91824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91824">
        <property type="protein sequence ID" value="PRC91824"/>
        <property type="gene ID" value="S2091_3380"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009427">
        <property type="term" value="C:bacterial-type flagellum basal body, distal rod, L ring"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003774">
        <property type="term" value="F:cytoskeletal motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071973">
        <property type="term" value="P:bacterial-type flagellum-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00415">
        <property type="entry name" value="FlgH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000527">
        <property type="entry name" value="Flag_Lring"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34933">
        <property type="entry name" value="PTHR34933"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02107">
        <property type="entry name" value="FlgH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01008">
        <property type="entry name" value="FLGLRINGFLGH"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0975">Bacterial flagellum</keyword>
    <keyword evidence="5" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="6" id="KW-0966">Cell projection</keyword>
    <keyword evidence="6" id="KW-0969">Cilium</keyword>
    <keyword evidence="6" id="KW-0282">Flagellum</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC91824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="234" mass="24944" checksum="D1EA66C11A7DC815" modified="2018-07-18" version="1">MRQTYLNKPGKTQWKMCSVLLGVVCSLVGCAITPKPIIDQPMSARPLPEAPHDKGNPGAIFQASNYQPLFEDVRARMVGDSIIITIAENTSSTTTTGNTTSKTSATSYAAPNLFGATAAKTAKLSLGTTTGNSLTEKGGDNFGNTFSGTIAVTITEVLPNGNFKVSGEKKLAFDRDTEYVRFSGVISPTTIAAGNIVSSTQVANAKFEYRTNAHLDSSELMSILDRFFLSFIPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GW33</accession>
    <name>A0A2S9GW33_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Probable potassium transport system protein kup</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">kup</name>
        <name evidence="12" type="ORF">S2091_3277</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Transport of potassium into the cell.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cell membrane</location>
            <topology evidence="11">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the HAK/KUP transporter (TC 2.A.72) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000017">
        <property type="protein sequence ID" value="PRC91935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91935">
        <property type="protein sequence ID" value="PRC91935"/>
        <property type="gene ID" value="S2091_3277"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015079">
        <property type="term" value="F:potassium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01522">
        <property type="entry name" value="Kup"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003855">
        <property type="entry name" value="K+_transporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023051">
        <property type="entry name" value="K+_uptake_low_affin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30540">
        <property type="entry name" value="PTHR30540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02705">
        <property type="entry name" value="K_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 11" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9 11" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 11" id="KW-0630">Potassium</keyword>
    <keyword evidence="5 11" id="KW-0633">Potassium transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="52"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="105"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="144"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="174"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="215"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="250"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="286"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="342"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="369"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="398"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="428"/>
            <end position="445"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01522"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PRC91935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="627" mass="68721" checksum="245E27BDA8599BE5" modified="2018-07-18" version="1">MSSQFQPTKSSTPALTIAAVGIVYGDIGTSPLYTMQTIFSKEYGLDLTNANILGVVSLIMWGLFIVVALKYVTLILRADNRGEGGIIALMALALESVGKKSRWSYALLLLGLFGAALFYGDGVITPAMSVISAIEGLNVATPSFSTYVVPITVVVLITLYSFQHKGTAGIGKWFGPIMVLWFIALAVMGVLNILKAPIILIALNPFHAFAFLMHHGWLAFVALGAVVLAFTGAEALYADMGHFGRKPIRLAWFGIVFPALMLNYLGQGGLLMTNAAAVENPFYYQLGAWSIYPLVALSTVAAVIASQATISGTYSMTKEAISLGLLPRLSIIHTSVKEIGQIYMPMVNWIQLAAVLGAVVGFGSSANLAAAYGIAVTATMLITTVLTFFVIRQAWKYNIVLCVAATGFFFIIDTAFFSANALKIMHGGWFPLVLGSIMFTVMLTWHKGRELVFQNLRVHAIPLKDFLASLFIAPPHRVGGTAIFLRSASEGVPHALLHNLSHNKILHERVIFLTVYNQEIPWVPFNERVRVIALGNECYQLDVFYGFKNEPDIPQALELAEAKGLKFEIMETSFFVTRQTIVSRPQHEMSAWREWLFVIMSRTARDAADYYHIPSNRVIEVGSQVEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GW98</accession>
    <name>A0A2S9GW98_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Helix-turn-helix domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3341</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000017">
        <property type="protein sequence ID" value="PRC91999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91999">
        <property type="protein sequence ID" value="PRC91999"/>
        <property type="gene ID" value="S2091_3341"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018062">
        <property type="entry name" value="HTH_AraC-typ_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020449">
        <property type="entry name" value="Tscrpt_reg_HTH_AraC-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00032">
        <property type="entry name" value="HTHARAC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00041">
        <property type="entry name" value="HTH_ARAC_FAMILY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="2">
        <location>
            <begin position="156"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="259" mass="28822" checksum="7039F133632E5935" modified="2018-07-18" version="1">MSDISFAFHKVFDQPFDTGVRSFAQPYLLFASVGAFHVDSADRTWLLPPYRAALIQANAPVRIWSTAPAVSSSVLFASDLTPTSTLASMPALDCQVFRVSTLLHQMINYATQWDVDKAALDPASQSFFQALAHVVGTASAETENLWFPRARSSDLERAIAFTLETLKEETAFSEVARVAIVSERTLSRRFLDELGMSWIEFVQRARIVRATEGLVMGDASIAELAYTWGFSSASSFAQKFRQLMGETPTQYRQRLRAAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GW99</accession>
    <name>A0A2S9GW99_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">PEP phosphonomutase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3278</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000017">
        <property type="protein sequence ID" value="PRC91936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91936">
        <property type="protein sequence ID" value="PRC91936"/>
        <property type="gene ID" value="S2091_3278"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00377">
        <property type="entry name" value="ICL_PEPM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039556">
        <property type="entry name" value="ICL/PEPM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_Kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="SSF51621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="273" mass="28891" checksum="AC9B5F93AEFA8AB2" modified="2018-07-18" version="1">MLTQAEKGKAFRALHENKGAFIIPNPWDVGTARLLASLGFESLATTSAGYAFSVGQPDNTIARDEMIAHVAAIVSATDLPVSADLENGFGDTPESVAQTIRLAAAAGLVGGSIEDSTNRPDDPIYGHELAVERILAASEVVRTLPFPFTLTGRAENYMVGRRDINDTIKRLQAYQEAGADVLYAAGLSSKEDIAAVVSSVDRPVNVVMGLQGAQLSLAELSAIGVKRISVGSALSRAALGAFLRAAREMREDGTFDFANEAVSYKEINAMFKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWG8</accession>
    <name>A0A2S9GWG8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ribonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_3204</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ribonuclease N1/T1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000016">
        <property type="protein sequence ID" value="PRC92069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92069">
        <property type="protein sequence ID" value="PRC92069"/>
        <property type="gene ID" value="S2091_3204"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004521">
        <property type="term" value="F:endoribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000026">
        <property type="entry name" value="Gua-sp_ribonuclease_N1/T1/U2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016191">
        <property type="entry name" value="Ribonuclease/ribotoxin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00545">
        <property type="entry name" value="Ribonuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53933">
        <property type="entry name" value="SSF53933"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015418038" evidence="4">
        <location>
            <begin position="37"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC92069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="136" mass="15159" checksum="4A953EA6DEAACA4B" modified="2018-07-18" version="1">MAASIEKLSILLMMNNLKTWLLAIACSALFCLPCFAEADTGLAQVRFDQLPVSAQKTLGLIKQNGPFPFDKDGVVFGNYEGILPKQKRGYYHEYTVPTAGAKNRGAQRIVMGGTLQNSPDFYYTNDHYASFKRIQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWL1</accession>
    <name>A0A2S9GWL1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ABC-type branched-chain amino acid transport system permease component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_3216</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000016">
        <property type="protein sequence ID" value="PRC92081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92081">
        <property type="protein sequence ID" value="PRC92081"/>
        <property type="gene ID" value="S2091_3216"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015658">
        <property type="term" value="F:branched-chain amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06581">
        <property type="entry name" value="TM_PBP1_LivM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001851">
        <property type="entry name" value="ABC_transp_permease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043428">
        <property type="entry name" value="LivM-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30482">
        <property type="entry name" value="PTHR30482"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02653">
        <property type="entry name" value="BPD_transp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="15"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="47"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="122"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="151"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="220"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="270"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="305"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC92081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="403" mass="43214" checksum="CF562A23817BF124" modified="2018-07-18" version="1">MSTVFDIKANPKRAYSSFAMLAVVLIAFPFIAANFGNSWVRIIDMALLYIMLALGLNIVVGFAGLLDLGYIAFYAIGAYMTGLLASPQFAAVLESFVNTYPPVGEFLIWICGPEIVQNGIHLSVWLIVPLGAAVAAFFGALLGAPTLKLRGDYLAIVTLGFGEIIRIFMNNLNAPVNITNGPQGINMIDPIRIFGVSLAGEEGSKATVFIGHFSMPSVNAYYFLFLLLCIAIVFITVRLQHSRLGRAWVAIREDEIAAKAMGINTRNIKLLAFSMGASFAGVAGAMFAAFQGFVSPESFSLNESIAVLAMVVLGGIGHVPGVILGGALLAALPEVLRHVVEPLQMTLFGTVLVEAEVMRQLLYGLAMVVIMLYRPAGLWPSPKHEDRVLDLPDDSTDPSNVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWT3</accession>
    <name>A0A2S9GWT3_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Succinate dehydrogenase iron-sulfur subunit</fullName>
            <ecNumber evidence="7">1.3.5.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">S2091_3101</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>a quinone + succinate = a quinol + fumarate</text>
            <dbReference type="Rhea" id="RHEA:40523"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="EC" id="1.3.5.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>2Fe-2S cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49601"/>
        </cofactor>
        <text evidence="7">Binds 1 [2Fe-2S] cluster.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>[3Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:21137"/>
        </cofactor>
        <text evidence="7">Binds 1 [3Fe-4S] cluster.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="7">Binds 1 [4Fe-4S] cluster.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.5.1" evidence="7"/>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92185">
        <property type="protein sequence ID" value="PRC92185"/>
        <property type="gene ID" value="S2091_3101"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051538">
        <property type="term" value="F:3 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008177">
        <property type="term" value="F:succinate dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1060.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009051">
        <property type="entry name" value="Helical_ferredxn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004489">
        <property type="entry name" value="Succ_DH/fum_Rdtase_Fe-S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025192">
        <property type="entry name" value="Succ_DH/fum_Rdtase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13085">
        <property type="entry name" value="Fer2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="SSF54292"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00384">
        <property type="entry name" value="dhsB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="6 7" id="KW-0003">3Fe-4S</keyword>
    <keyword evidence="7" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="4 7" id="KW-0408">Iron</keyword>
    <keyword evidence="5 7" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="8">
        <location>
            <begin position="5"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="9">
        <location>
            <begin position="137"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC92185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="236" mass="26835" checksum="1E6D6648ACF1AD81" modified="2018-07-18" version="1">MARTLKFQIYRYDPDKDAKPYMQDLSVELQDTDKMLLDALQRIKADVDDSLSLRRSCREGVCGSDAMNINGKNGLACTTNLNELKEPIVLRPLPGLPVIRDLIVDMTQFFKQYNSIKPFLINDSIPPEKERLQSPAEREELDGLYECILCACCSTSCPSFWWNPDKFVGPAGLLQAYRFIADSRDEATGERLDNLEDPYRLFRCKTIMNCVDVCPKGLNPTKAIGKIKELMVRRAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWU6</accession>
    <name>A0A2S9GWU6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3108</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92192">
        <property type="protein sequence ID" value="PRC92192"/>
        <property type="gene ID" value="S2091_3108"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015640354" evidence="2">
        <location>
            <begin position="23"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="121"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="154" mass="17292" checksum="45BC7311713B20B3" modified="2018-07-18" version="1">MNWFKRASAVLLVSLCSACANSPPVIDTNVTINFPEVAPIVSVEQADAALEAVALSRAQIDWRFRQKEQICYTKFFMNHCMLEAKEQRRIDLATVKKSEVAANYFKRKNNVEEMDRALVEKNLAHPLPGTTPNDDAENKSDKPATTDLVKKPVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWZ8</accession>
    <name>A0A2S9GWZ8_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 13">Replicative DNA helicase</fullName>
            <ecNumber evidence="4 13">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">S2091_3161</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 13">Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O = ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the helicase family. DnaB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="4 13"/>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92245">
        <property type="protein sequence ID" value="PRC92245"/>
        <property type="gene ID" value="S2091_3161"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990077">
        <property type="term" value="C:primosome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006269">
        <property type="term" value="P:DNA replication, synthesis of RNA primer"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00984">
        <property type="entry name" value="DnaB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.860.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036185">
        <property type="entry name" value="DNA_heli_DnaB-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007692">
        <property type="entry name" value="DNA_helicase_DnaB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007694">
        <property type="entry name" value="DNA_helicase_DnaB-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007693">
        <property type="entry name" value="DNA_helicase_DnaB-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016136">
        <property type="entry name" value="DNA_helicase_N/primase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00772">
        <property type="entry name" value="DnaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03796">
        <property type="entry name" value="DnaB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48024">
        <property type="entry name" value="SSF48024"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00665">
        <property type="entry name" value="DnaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51199">
        <property type="entry name" value="SF4_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 13" id="KW-0235">DNA replication</keyword>
    <keyword evidence="12 13" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="10 13 15" id="KW-0347">Helicase</keyword>
    <keyword evidence="9 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 13" id="KW-0639">Primosome</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SF4 helicase" evidence="14">
        <location>
            <begin position="189"/>
            <end position="455"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008428"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00021957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU362085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="PRC92245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="462" mass="51051" checksum="5BAD6B86DF572C7D" modified="2018-07-18" version="1">MNKPSDPQLDALRVPPHSIESEQSVLGGLLLDNAAWDRIADFINADDFYRYDHRIIFQAIIKLISATRPADVITVYEALSSIGRADEVGGLAYLNALAQNTPSAANIRRYAEIVRDRGVLRKLITVADEISGNAFNPQGKEVKQMLDEAESKIFSIAEEGARGSQGFQEIQPLLKQVVERIDELYNRDNQNDITGVPTGFADLDKMTSGLQPGDLIIVAGRPSMGKTAFSINIGEHVAIESGLPVAVFSMEMGGAQLAMRMLGSVGRLDQHRLRTGKLNDEDWPRLTHAIQKMNDAQLYIDETPALNSIELRARSRRLSRQCGKLGLIVIDYLQLMSANSSGENRATEISEISRNLKGLAKELNCPVIALSQLNRSLEQRPNKRPVMSDLRESGAIEQDADVILFIYRDQVYNPDSPDKGTAEIIIGKQRNGPIGSVRLTFMGEYTKFENYTGSLSVYGDSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GX48</accession>
    <name>A0A2S9GX48_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">3-oxoacid CoA-transferase, A subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2954</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 3-oxoacid CoA-transferase subunit A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92295">
        <property type="protein sequence ID" value="PRC92295"/>
        <property type="gene ID" value="S2091_2954"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008410">
        <property type="term" value="F:CoA-transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012792">
        <property type="entry name" value="3-oxoacid_CoA-transf_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004165">
        <property type="entry name" value="CoA_trans_fam_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004163">
        <property type="entry name" value="CoA_transf_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13707">
        <property type="entry name" value="PTHR13707"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01144">
        <property type="entry name" value="CoA_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00882">
        <property type="entry name" value="CoA_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02429">
        <property type="entry name" value="pcaI_scoA_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01273">
        <property type="entry name" value="COA_TRANSF_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="239" mass="25688" checksum="843A14E23D4DBEAD" modified="2018-07-18" version="1">MNKLYPDANTALKDIVKDGQTIAVGGFGLCGIPEALIGALRDSGVQNLTAISNNAGVDGFGLGQLLTTRQIKKMISSYVGENKEFERQYLAGELALEFTPQGTLAEKLRAGGAGIPAFFTKTGVGTIVAEGKEIREFDGHNYVMERALVADVSLVKAYKADKAGNLVYRKTARNFNPNVAMAGKITVAEVEHIVEIGELDPDEIHTPGIYVHRIVLNTTPEKRIEQRTLTVAATTKAGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GX62</accession>
    <name>A0A2S9GX62_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphoesterase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2957</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92298">
        <property type="protein sequence ID" value="PRC92298"/>
        <property type="gene ID" value="S2091_2957"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007312">
        <property type="entry name" value="Phosphoesterase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31956">
        <property type="entry name" value="PTHR31956"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04185">
        <property type="entry name" value="Phosphoesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015733519" evidence="1">
        <location>
            <begin position="18"/>
            <end position="813"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="813" mass="84285" checksum="01E00B1D03930D9B" modified="2018-07-18" version="1">MKLSPLALACSALVVLAGCHSGSSSVATPPSVNGIASAGAPLVGVVVTATDSSGNVIQSTPTDATGKFAIALGGSGPYVLTTPFNDADGSPALLSSVYVPSGVFAGSLQANINPLTSLITSRVLGAIPSAAPTGAQITTAAITPTTVANAELAITTLLQPIYTALAIPATETADPIGTTVYKANSSDPLDNLFTLAHFMVHSGQISIGTDANRAVINVPATGTLASSIPTTAVTSLVALNAGGTTTPITNVIVVIGENQTFDAVFGTYPAPQGQTVNNLLSEGIINADGTPGPNFNLALQNQGATQTTYSINPTRSVAYATLPQPLQIGELTSSLATLGGTPDPHFPANLANGPFQLTKYVPYAVTASNPIGVTTGDPVHRFFQMWQQTGGNNAKLDMFTWVADSVGQGGDTSGVTPANPSQGGELMAFLNMQAGDVPYLKSLAQSYALSDNYHQSILGGTGANFFAIATADSPYFNTAGAVAAPPANQIENPNPMAGTPNFYTQDGYSGGSYVNCSDSTQPGVAPILAALTAVNVPSNCDTGKYYLVNNYAPGYDMNGNVQPIGPKNYNYPPQTVPTIAEALANKGVSWKWYTGAREIADVTADATALGLPASAGVYALLQSAQYNAIGDPLVASQNVMTSTSLKAGLAGLTTFYNDVKNSTLPAVSFVVPKNLDSGHPGYSVEMKYELFLQNLVAQVKANPTLWAHTAIIITTDEGGGHFDTGAIQNMDFFGDGPRIPMLVVSPYARTNYIDHTYHDHASVLKFIERNWKLPPLSARSRDNHPIPVTTSANLYKPTNTTPAIGDLMSMFNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXA4</accession>
    <name>A0A2S9GXA4_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">dITP/XTP pyrophosphatase</fullName>
            <ecNumber evidence="7">3.6.1.66</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Non-canonical purine NTP pyrophosphatase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Non-standard purine NTP pyrophosphatase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Nucleoside-triphosphate diphosphatase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Nucleoside-triphosphate pyrophosphatase</fullName>
            <shortName evidence="7">NTPase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_3013</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>H2O + ITP = diphosphate + H(+) + IMP</text>
            <dbReference type="Rhea" id="RHEA:29399"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <dbReference type="ChEBI" id="CHEBI:61402"/>
            <dbReference type="EC" id="3.6.1.66"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>H2O + XTP = diphosphate + H(+) + XMP</text>
            <dbReference type="Rhea" id="RHEA:28610"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57464"/>
            <dbReference type="ChEBI" id="CHEBI:61314"/>
            <dbReference type="EC" id="3.6.1.66"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>dITP + H2O = dIMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:28342"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61194"/>
            <dbReference type="ChEBI" id="CHEBI:61382"/>
            <dbReference type="EC" id="3.6.1.66"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="7">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7 8">Belongs to the HAM1 NTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.66" evidence="7"/>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92354">
        <property type="protein sequence ID" value="PRC92354"/>
        <property type="gene ID" value="S2091_3013"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035870">
        <property type="term" value="F:dITP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036220">
        <property type="term" value="F:ITP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017111">
        <property type="term" value="F:nucleoside-triphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036222">
        <property type="term" value="F:XTP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009117">
        <property type="term" value="P:nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009146">
        <property type="term" value="P:purine nucleoside triphosphate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00515">
        <property type="entry name" value="HAM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01405">
        <property type="entry name" value="Non_canon_purine_NTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020922">
        <property type="entry name" value="dITP/XTP_pyrophosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002637">
        <property type="entry name" value="Ham1p-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029001">
        <property type="entry name" value="ITPase-like_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11067">
        <property type="entry name" value="PTHR11067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01725">
        <property type="entry name" value="Ham1p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52972">
        <property type="entry name" value="SSF52972"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00042">
        <property type="entry name" value="TIGR00042"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 7" id="KW-0546">Nucleotide metabolism</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="16"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="160"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="188"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="77"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="48"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="77"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="78"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="183"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC92354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="203" mass="21935" checksum="8B8550A2310EA5F3" modified="2018-07-18" version="1">MSKLMDKLANKLILASGNLGKLKELSAMLAPLGIEVHTQTSFGVSEAEEPFNTFIENALTKARHAARSTGFPALADDSGLCVNALGGEPGVQSARFAGEPKSDARNNQKLVAALSNLDDKTAYYYSVCVLVRHADDPQPIIADGRWNGEICAEPRGTNGFGYDAHFWLPELGKTAAELAPEQKNQLSHRGLAMRQLLEKLTEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXC0</accession>
    <name>A0A2S9GXC0_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Putative fluoride ion transporter CrcB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">crcB</name>
        <name evidence="11" type="ORF">S2091_3026</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 10">Important for reducing fluoride concentration in the cell, thus reducing its toxicity.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cell membrane</location>
            <topology evidence="10">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the CrcB (TC 9.B.71) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92367">
        <property type="protein sequence ID" value="PRC92367"/>
        <property type="gene ID" value="S2091_3026"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:1903425">
        <property type="term" value="F:fluoride transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00454">
        <property type="entry name" value="CrcB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003691">
        <property type="entry name" value="CrcB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28259">
        <property type="entry name" value="PTHR28259"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02537">
        <property type="entry name" value="CRCB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00494">
        <property type="entry name" value="crcB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="5 10" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="35"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="67"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="103"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC92367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="126" mass="13390" checksum="935B50C2BEB306E3" modified="2018-07-18" version="1">MFYSIVVISVGASCGAVLRWVLGMQLNALFPTIPLGTLAANLFGGYMIGLAIGYFGEHPLISPEMRLLIITGFLGGLTTFSTFSAEVASLLQEGRFGWALGTIGLHVVGSVLLTILGIMTISYFRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXF1</accession>
    <name>A0A2S9GXF1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Zinc-finger domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2774</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92399">
        <property type="protein sequence ID" value="PRC92399"/>
        <property type="gene ID" value="S2091_2774"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019401">
        <property type="entry name" value="Znf_CHCC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10276">
        <property type="entry name" value="zf-CHCC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="zf-CHCC" evidence="1">
        <location>
            <begin position="28"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF10276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="62" mass="6870" checksum="442B586BDE74F71C" modified="2018-07-18" version="1">MQTKNIVELDLTDLPAHCPNPAMPLWSSHPKVFLDLSHNGHATCPYCSTEYQLKAGVVLKAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXH7</accession>
    <name>A0A2S9GXH7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Conserved protein/domain typically associated with flavoprotein oxygenases DIM6/NTAB family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2794</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92419">
        <property type="protein sequence ID" value="PRC92419"/>
        <property type="gene ID" value="S2091_2794"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016646">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002563">
        <property type="entry name" value="Flavin_Rdtase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01613">
        <property type="entry name" value="Flavin_Reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00903">
        <property type="entry name" value="Flavin_Reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavin_Reduct" evidence="2">
        <location>
            <begin position="30"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="176" mass="19084" checksum="293F622B17B6AFBF" modified="2018-07-18" version="1">MQSDNSHKPMNKSKPSSKKTFDTRHFKSALSQFATGVTVITTRLANGSFLGITASSFNSVSLDPPLVLWSLSERANSLPVFTGNSHYVINVLAADQTWLAEQFSKSATDRFAGVEFTLSATGLPILKGAAAWFECHNRSRYPEGDHVIFVGEVEDCAFDPSTPLIFHGGQLLSSGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXL8</accession>
    <name>A0A2S9GXL8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2834</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92459">
        <property type="protein sequence ID" value="PRC92459"/>
        <property type="gene ID" value="S2091_2834"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="141" mass="15949" checksum="20C62AE9DD7296DA" modified="2018-07-18" version="1">MESSKLFRYELIKNYVALYAKKDVDGLIVLWEMMAVEIVALVGEGGFKLLYERCISLTQVTFPWLVVGPPLPQNGRRFVELRLRFEEQSIAQTNAANNQLLITFTDLLASLIGEQITVVILHTAMGNSKTENNSTKELENE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXZ3</accession>
    <name>A0A2S9GXZ3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">LytTr DNA-binding domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2633</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92578">
        <property type="protein sequence ID" value="PRC92578"/>
        <property type="gene ID" value="S2091_2633"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007492">
        <property type="entry name" value="LytTR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04397">
        <property type="entry name" value="LytTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00850">
        <property type="entry name" value="LytTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50930">
        <property type="entry name" value="HTH_LYTTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH LytTR-type" evidence="1">
        <location>
            <begin position="1"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="105" mass="12229" checksum="487456D203AB2BB7" modified="2018-07-18" version="1">MLVKDGDNCHLLSLDSIRYIESCKNYVQIFFDNKRAYVKKSLNGIEQRLPKKHFFRANRQHIVNLDAIRAIEESISEGYTITLNDGKILDVSRRNAVELKELLSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GY47</accession>
    <name>A0A2S9GY47_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2702</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92647">
        <property type="protein sequence ID" value="PRC92647"/>
        <property type="gene ID" value="S2091_2702"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042095">
        <property type="entry name" value="SUMF_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="SSF56436"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="308" mass="33583" checksum="610FE58F713935B8" modified="2018-07-18" version="1">MNAVIEKTELNQAQVGLYKKFTVARTDGSSEPGGKHEHDEYFVLNLTTDKHALPALKAYAKSCASEFPILATNLRAKAKALNHDEYVTVPETTLPNGVVVPEFKVGKYITGCEDEQLAINAVAAPWVEINFHDAKAEAEKSGLKLITETQYLAIAHNIAQQAINWTSGVVGEGSIFQGIRNGDYDEAQPGTFVSEDETERRWHELSNGERVFDFAGNCYSWIFDDVQGDENGIVNKEFAADSPSITTAPAPSMNKGCGWYPNAGNDWSGSALVRGGCWDSGDYAGVFLLYYGGPACEYGNVGFRCTIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GY55</accession>
    <name>A0A2S9GY55_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2685</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92630">
        <property type="protein sequence ID" value="PRC92630"/>
        <property type="gene ID" value="S2091_2685"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="191"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="373" mass="41070" checksum="69C0E003CCB1F489" modified="2018-07-18" version="1">MNTQITLPERAKVALKSAEHELALIELAAKSADIKEVLNADGRAQAHSAGMALRNTRTSIAATGKAAREDATKFSKAIIEEENRLIALIEPEEKRVLGLRDVWDTKIEAEKQAKIEANRKRISAIQERIAAVKVLPTVLAGTVSSKISESIISLTLKTDFEFFEEFEPEYKLVRSDVINKLTAMETNQREIEVEEDSRRQEEARQKLAQEQESARIKAEQERIAEQQAKERAELDRQRAEQAAIQAGINAKLELEHAALAKLQQEARAEADKLAADKAEFEAKEQAEINATALKQAEMVAAQALVEATAQAEAAATQAACVRLTAIPASCTEKPDQPSDAELLDAIAKRFHVPAKTALIWLSRMDYSSLSIAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYI2</accession>
    <name>A0A2S9GYI2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2501</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DinB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92771">
        <property type="protein sequence ID" value="PRC92771"/>
        <property type="gene ID" value="S2091_2501"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007837">
        <property type="entry name" value="DinB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034660">
        <property type="entry name" value="DinB/YfiT-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37302">
        <property type="entry name" value="PTHR37302"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05163">
        <property type="entry name" value="DinB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109854">
        <property type="entry name" value="SSF109854"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="169" mass="19496" checksum="6A71B93CC3C7BB44" modified="2018-07-18" version="1">MSTLTLLHTLFEYQAWANGEFLEKMKSFDAELHNDRRHTAMRLINHTCIVSQIFAAHLTGANHNLTTDNPIDTPSLEDLREAVAASDRWYLTYLENLTPDQLSESIPFVFTDGDKGYMSREEMLTHVVVHHGYHRGEVGRIMGQISLPIPWDTYAVYLHQTEPLRRLKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYN1</accession>
    <name>A0A2S9GYN1_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 10">Adenosine 5'-phosphosulfate reductase</fullName>
            <shortName evidence="10">APS reductase</shortName>
            <ecNumber evidence="6 10">1.8.4.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9 10">5'-adenylylsulfate reductase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8 10">Thioredoxin-dependent 5'-adenylylsulfate reductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">cysH</name>
        <name evidence="12" type="ORF">S2091_2562</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4 10">Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>[thioredoxin]-disulfide + AMP + 2 H(+) + sulfite = [thioredoxin]-dithiol + adenosine 5'-phosphosulfate</text>
            <dbReference type="Rhea" id="RHEA:21976"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17359"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="ChEBI" id="CHEBI:58243"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="1.8.4.10"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="10">Binds 1 [4Fe-4S] cluster per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5 10">Sulfur metabolism; hydrogen sulfide biosynthesis; sulfite from sulfate.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the PAPS reductase family. CysH subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.8.4.10" evidence="6 10"/>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92832">
        <property type="protein sequence ID" value="PRC92832"/>
        <property type="gene ID" value="S2091_2562"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00340">
        <property type="reaction ID" value="UER00458"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004604">
        <property type="term" value="F:phosphoadenylyl-sulfate reductase (thioredoxin) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019344">
        <property type="term" value="P:cysteine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019379">
        <property type="term" value="P:sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01713">
        <property type="entry name" value="PAPS_reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00063">
        <property type="entry name" value="CysH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011798">
        <property type="entry name" value="APS_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004511">
        <property type="entry name" value="PAPS/APS_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002500">
        <property type="entry name" value="PAPS_reduct"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01507">
        <property type="entry name" value="PAPS_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000857">
        <property type="entry name" value="PAPS_reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02055">
        <property type="entry name" value="APS_reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00434">
        <property type="entry name" value="cysH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="10" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PAPS_reduct" evidence="11">
        <location>
            <begin position="38"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile; cysteine thiosulfonate intermediate" evidence="10">
        <location>
            <position position="233"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="122"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="123"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="205"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="208"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00024298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00024327"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00029514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00030894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00032041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PRC92832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="247" mass="27672" checksum="8B5A033EE144AFAB" modified="2018-07-18" version="1">MTQATTRNTLNEPAGFAQRLNETQITLARIANAFSPAVFASSLAAEDMVLTDLILKNKTNIGIFSLETGRLPVETLNVLEQVKQTYGYQIKLFYPNPAAVAAYVENKGLNGFYESVELRKECCQIRKVEPLGRALAGNKAWVTGQRRSQSSTRASLDVQEQDEAHGLAKFNPLADWSEDDVWYYLQQHKVPYNALHDQGYPSIGCAPCTRAIQPGEDIRAGRWWWETPESKECGLHVVDGKLVRIQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYS7</accession>
    <name>A0A2S9GYS7_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">T2SSC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_2286</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92869">
        <property type="protein sequence ID" value="PRC92869"/>
        <property type="gene ID" value="S2091_2286"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024961">
        <property type="entry name" value="T2SS_GspC_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11356">
        <property type="entry name" value="T2SSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="T2SSC" evidence="6">
        <location>
            <begin position="62"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="132"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="150"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="183"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF11356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC92869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="206" mass="22125" checksum="26CD0AED82312F23" modified="2018-07-18" version="1">MKRIPLISSFILFILLCATSSYWVLQLIKPETRKISAPQITKPTADVESVAGLFGGAMAVDTNYQLKGVVLANPMGQSVAIIAVDGKPTQAYPMNTELSPGVTLNEVHSGYILLLDNGISKRVDLPQDSKASMQTMNTVPDRYPNPVANPVMNDQRSNVENTGGNRGNKSRLSQLQTLNLPPPNAVAPVPTPTPTPIDADNKPADH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYT2</accession>
    <name>A0A2S9GYT2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="9">GspF: type II secretion system protein F</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_2285</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GSP F family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92868">
        <property type="protein sequence ID" value="PRC92868"/>
        <property type="gene ID" value="S2091_2285"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015627">
        <property type="term" value="C:type II protein secretion system complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015628">
        <property type="term" value="P:protein secretion by the type II secretion system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.81.30">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003004">
        <property type="entry name" value="GspF/PilC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011850">
        <property type="entry name" value="T2SS_GspF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018076">
        <property type="entry name" value="T2SS_GspF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042094">
        <property type="entry name" value="T2SS_GspF_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30012">
        <property type="entry name" value="PTHR30012"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00482">
        <property type="entry name" value="T2SSF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00812">
        <property type="entry name" value="BCTERIALGSPF"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02120">
        <property type="entry name" value="GspF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="168"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="212"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="372"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="domain" description="T2SSF" evidence="8">
        <location>
            <begin position="70"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="domain" description="T2SSF" evidence="8">
        <location>
            <begin position="273"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC92868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="404" mass="44502" checksum="0DA4C90A7125BE2D" modified="2018-07-18" version="1">MPAFRYEALLADGQNKTGVINADSARAARAELRGQGLTPIQLEQIANEQQNKSQRALFADKLSTTELSLFTRQLASLLEAGLPLEQSFSALLEQAERVYVRDLIAAIRSEVMAGHSLSDVLKQHPRDFADIYTALVASGEQIGQLSRVLSRLADFIERRNALVQKVKLAFTYPAIVTVVAFAIVIFLLAYVVPQIVSVFANTKQKLPILTVIMLAISDFVRAYGIIVAVVFSFGLWAWLQVLKNPEVKMRWHSWLLTAPLYGKFERSVNTSRFASTLAITIGSGVPILQALQTSRDTLSNVAMREQVESATAAVREGVSLARALSSHQYFPPMLIHMIRAGEVTGNLPAMLERASDSQQQDLERRALTMAGLLEPVLILAMGVVVLLIVLAVLMPIIEINQLVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYU9</accession>
    <name>A0A2S9GYU9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2322</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92905">
        <property type="protein sequence ID" value="PRC92905"/>
        <property type="gene ID" value="S2091_2322"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="106" mass="11831" checksum="B932AA5EEF174136" modified="2018-07-18" version="1">MHCVFIQLVGLKCNAQHSSCEHILLNCIFAFITMQAEVYSTSKLSNVSTRRVSVANKCLKAGSNLNYLGTLLGLAIYYFMRLPLVDDVFTRSSYSGYLSLPQSQIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZ03</accession>
    <name>A0A2S9GZ03_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Rhodanese-like domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2368</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92951">
        <property type="protein sequence ID" value="PRC92951"/>
        <property type="gene ID" value="S2091_2368"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="SSF52821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rhodanese" evidence="1">
        <location>
            <begin position="33"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="150" mass="16630" checksum="F8621AF6851024E4" modified="2018-07-18" version="1">MTKAILDQAQQRGMSLPYAGAVTPQEAFQLLESDTAVQLIDVRTNAERDWVGQVQINPAQLHAVQWNLYPTKHNADFLSELAAQVADKETVLLFLCRSGVRSRSAAQLATEHGYTQCYDILEGFEGDKDQHGHRKAIAGWCHAGLPWRGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZ17</accession>
    <name>A0A2S9GZ17_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Response regulator receiver domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2391</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92974">
        <property type="protein sequence ID" value="PRC92974"/>
        <property type="gene ID" value="S2091_2391"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="7"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="129" mass="14223" checksum="FA1D80404B93BDE6" modified="2018-07-18" version="1">MADPNMKFLVVDDFSTMRRIVRNLLKELGYTNVDEAEDGAMGLAKLRNGQFDFVISDWNMPNMDGLTMLQQIRADPALSKLPVLMVTAEAKKENIIAAAQAGANGYVVKPFTAATLDEKLGKIFEKLGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZ83</accession>
    <name>A0A2S9GZ83_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Lipopolysaccharide biosynthesis protein LPS:glycosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2434</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC93017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93017">
        <property type="protein sequence ID" value="PRC93017"/>
        <property type="gene ID" value="S2091_2434"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008918">
        <property type="term" value="F:lipopolysaccharide 3-alpha-galactosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002495">
        <property type="entry name" value="Glyco_trans_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013645">
        <property type="entry name" value="Glyco_transf_8N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01501">
        <property type="entry name" value="Glyco_transf_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08437">
        <property type="entry name" value="Glyco_transf_8C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_transf_8C" evidence="2">
        <location>
            <begin position="165"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="220" mass="25853" checksum="52B8A8B2DE3DFA4F" modified="2018-07-18" version="1">MAPYSLDILTRLLIPSLLHGITDKVLYLDADIVCDEKINSFLALDLKGNVLAARTDNTPHNENKFGLKPNTYFNAGLLYIDINEWQEQDIYKKILKALEVNKNIFLPDQDALNIVLQGKVTYLPQNHHYHYFFDKPNHEIVTKKIFIHYLGCIKPWHGIFSETVPFNKYKANSPWKDYKHSWVSATSLQLRVYARYLFRQKKYISGFKYFFKYLKIKIAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZ84</accession>
    <name>A0A2S9GZ84_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF4398 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2430</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC93013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93013">
        <property type="protein sequence ID" value="PRC93013"/>
        <property type="gene ID" value="S2091_2430"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025511">
        <property type="entry name" value="DUF4398"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14346">
        <property type="entry name" value="DUF4398"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4398" evidence="2">
        <location>
            <begin position="34"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="76"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="125" mass="13174" checksum="B79BC72BE235017A" modified="2018-07-18" version="1">MTTISNQYVQAACFATIILIAGCTDMKTPTTADVAVSTAAVDNASSAGGAEYAPLEMRSARDKLALANTAMKDKDYKKADDLAKQAQADAKLAQSKANTAKAQAAVNTLQDDIHTLQDQIDRANH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZ86</accession>
    <name>A0A2S9GZ86_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2131</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93045">
        <property type="protein sequence ID" value="PRC93045"/>
        <property type="gene ID" value="S2091_2131"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="73"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="114"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="139" mass="14052" checksum="EE58F9F776DC98A7" modified="2018-07-18" version="1">MPASSHQLIFHGSLVLLFGLLLGAPYAKAIKNNAAANIINSWRVAHLSLPIGATLMFAIAAVLSALAVSAAIAWVIAVALIISAYGFCISTPLAAICGQRGLSSDATGLGKLVYLGNIVGASCSVIAAVALVYAAFISL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZA5</accession>
    <name>A0A2S9GZA5_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">GMP synthase [glutamine-hydrolyzing]</fullName>
            <ecNumber evidence="9">6.3.5.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">GMP synthetase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Glutamine amidotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">guaA</name>
        <name evidence="12" type="ORF">S2091_2147</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 9">Catalyzes the synthesis of GMP from XMP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ATP + H2O + L-glutamine + XMP = AMP + diphosphate + GMP + 2 H(+) + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:11680"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57464"/>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.5.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 9">Purine metabolism; GMP biosynthesis; GMP from XMP (L-Gln route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homodimer.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.2" evidence="9"/>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93061">
        <property type="protein sequence ID" value="PRC93061"/>
        <property type="gene ID" value="S2091_2147"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00189">
        <property type="reaction ID" value="UER00296"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003922">
        <property type="term" value="F:GMP synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016462">
        <property type="term" value="F:pyrophosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01742">
        <property type="entry name" value="GATase1_GMP_Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01997">
        <property type="entry name" value="GMP_synthase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00344">
        <property type="entry name" value="GMP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001674">
        <property type="entry name" value="GMP_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004739">
        <property type="entry name" value="GMP_synth_GATase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022955">
        <property type="entry name" value="GMP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025777">
        <property type="entry name" value="GMPS_ATP_PPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022310">
        <property type="entry name" value="NAD/GMP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00958">
        <property type="entry name" value="GMP_synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02540">
        <property type="entry name" value="NAD_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00884">
        <property type="entry name" value="guaA_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00888">
        <property type="entry name" value="guaA_Nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51553">
        <property type="entry name" value="GMPS_ATP_PPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 9" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="5 9 10" id="KW-0332">GMP biosynthesis</keyword>
    <keyword evidence="3 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 9 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 9 10" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GMPS ATP-PPase" evidence="11">
        <location>
            <begin position="203"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="9">
        <location>
            <position position="81"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="176"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="178"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="230"/>
            <end position="236"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PRC93061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="526" mass="57746" checksum="C74C6CA3301A3333" modified="2018-07-18" version="1">MHSKILILDFGSQVTQLIARRVRDAGVFSEVYPYDVSDEFIRNYGAAGIILSGGPNSVTEDETPRAPQAVFELGVPVLGICYGMQTMAAQLGGQVENGTVREFGYAEVRARGHTNLLKDIADFTTAEGHGMLKVWMSHGDKVNSMPVGFKLMASTDNCPIAGMADEERRFYAVQFHPEVTHTVQGAALLGRFVHEICGCKSDWNMPDYISEAVAAIRAQVGSDDVILGLSGGVDSSVAAALIHRAIGNQLTCVFVDHGLLRLDEGKMVMEMFAENLGVKVIRIDAAQQFMGHLAGVSDPEQKRKIIGREFVEVFQVESAKIKNAKWLAQGTIYPDVIESAGKGKKGHTIKSHHNVGGLPETLHLKLLEPLRELFKDEVRKLGVALGLPEAMVYRHPFPGPGLGVRILGEVKQDFADLLRRADAIFIEELRNTPVEGTDQNWYQATSQAFAVFLPVKSVGVMGDGRTYEYVVALRAVQTLDFMTAQWAHLPHELLGKVSNRIINEVRGINRVVYDISGKPPATIEWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZJ0</accession>
    <name>A0A2S9GZJ0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative oxidoreductases (Related to aryl-alcohol dehydrogenases)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2209</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93123">
        <property type="protein sequence ID" value="PRC93123"/>
        <property type="gene ID" value="S2091_2209"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NADP_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="SSF51430"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldo_ket_red" evidence="1">
        <location>
            <begin position="27"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="345" mass="37166" checksum="BC032754D4D897D4" modified="2018-07-18" version="1">MTNDTNNSAAQALPVRIIGSSLAVSALGFGAMGMSEFYGPSDDIASIKLLHEVAERGVTLIDTADLYGRGHNELLIGEFLRARRTLYNAGGLKIATKCGIERTTGGTPPRRINNSPEYIRSCCEASLKRLDVDCIDLYYIHRVDPAIPIEDTMDCLAGLVQEGKIAQVGLCEVSANTLGRAHRIHPVAALQTEYSLWSREVEDEILPMTQALGIGFIAYSPLGRGFLTGCLTQTDTLAEGDFRRANPRFQGDNMIHNLILLDTMRDMAARYGATPGQVALCWLLAQGDNIVPIPGTRRSAYLAENLGAASLTLASADLALLSETMTPHAVHGARYSSEGMQGINA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZN9</accession>
    <name>A0A2S9GZN9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">N-formylglutamate deformylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1940</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93202">
        <property type="protein sequence ID" value="PRC93202"/>
        <property type="gene ID" value="S2091_1940"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010247">
        <property type="entry name" value="HutG_amidohyd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007709">
        <property type="entry name" value="N-FG_amidohydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05013">
        <property type="entry name" value="FGase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02017">
        <property type="entry name" value="hutG_amidohyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="271" mass="30163" checksum="F1E9EF8EC260ADB3" modified="2018-07-18" version="1">MTNPFHFKAGHAPLLISMPHVGTTIPAEIGAEMDDIAQVKKDTDWHLPLLYNMAEQLGASVISAEYSRYVIDLNRPKEDSNLYPGQDTTGLCPVDTFGKQDLYRAGHLPDAPQIADRIEKYWQPYHSQLSSELARIKAQHGVAILWDAHSIASVVPRFFNGKLPDFNFGTADQKSCALELQAELAELMQKSAHATSFSHVFNGRFKGGYITRNYGNPANNIHAVQLEMSQCVYMNETAPFAYRPDLAAQVQPLLSELLAACLSWAKTRSKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZP0</accession>
    <name>A0A2S9GZP0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2263</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93177">
        <property type="protein sequence ID" value="PRC93177"/>
        <property type="gene ID" value="S2091_2263"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="80"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="119"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="148" mass="16793" checksum="4E5FB37A883F09D2" modified="2018-07-18" version="1">MKILSAFVAVISGIVLGNLIIYVSGYLAAIAIPREYFLWFGKPHITMALIIYDAIVMGLPRVIIATIWCVCTILVFRKKYLLLITAWCFGGYVLTQAYWDWKFDFGINYPTLFIQQPWAILSIIAAPCGILFAGIFFYKSHHANYLSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZW5</accession>
    <name>A0A2S9GZW5_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribosomal RNA small subunit methyltransferase I</fullName>
            <ecNumber evidence="6">2.1.1.198</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">16S rRNA 2'-O-ribose C1402 methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">rRNA (cytidine-2'-O-)-methyltransferase RsmI</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rsmI</name>
        <name evidence="8" type="ORF">S2091_1995</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>cytidine(1402) in 16S rRNA + S-adenosyl-L-methionine = 2'-O-methylcytidine(1402) in 16S rRNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42924"/>
            <dbReference type="Rhea" id="RHEA-COMP:10285"/>
            <dbReference type="Rhea" id="RHEA-COMP:10286"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74495"/>
            <dbReference type="ChEBI" id="CHEBI:82748"/>
            <dbReference type="EC" id="2.1.1.198"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the methyltransferase superfamily. RsmI family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.198" evidence="6"/>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93257">
        <property type="protein sequence ID" value="PRC93257"/>
        <property type="gene ID" value="S2091_1995"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070677">
        <property type="term" value="F:rRNA (cytosine-2'-O-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000453">
        <property type="term" value="P:enzyme-directed rRNA 2'-O-methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd11648">
        <property type="entry name" value="RsmI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1010.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01877">
        <property type="entry name" value="16SrRNA_methyltr_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000878">
        <property type="entry name" value="4pyrrol_Mease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035996">
        <property type="entry name" value="4pyrrol_Methylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014777">
        <property type="entry name" value="4pyrrole_Mease_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014776">
        <property type="entry name" value="4pyrrole_Mease_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008189">
        <property type="entry name" value="rRNA_ssu_MeTfrase_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018063">
        <property type="entry name" value="SAM_MeTrfase_RsmI_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46111">
        <property type="entry name" value="PTHR46111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00590">
        <property type="entry name" value="TP_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005917">
        <property type="entry name" value="MTase_YraL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53790">
        <property type="entry name" value="SSF53790"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00096">
        <property type="entry name" value="TIGR00096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01296">
        <property type="entry name" value="RSMI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 6 8" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="5 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 6 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TP_methylase" evidence="7">
        <location>
            <begin position="21"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC93257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="298" mass="32020" checksum="237A9EDFF600510A" modified="2018-07-18" version="1">MTELHPLLSHAAQQSYPASCLYVVATPIGNVADISFRALYVLSKVDAIACEDTRNTAQLLKQLGVFKPLIAAHQHNENEVAQKIIQRLQQGESIALVSDAGTPAVSDPGARIVDAVRAAGMKVVPLPGASAVITALSASGLLNDQFYFVGFLPSKAGQRDSVLNTLKHTTATLVFYEAPHRIIDTITALAALFPSTRKIVLARELTKLFEEIHRCELGAASAWLAADTHREKGEYVVLLEGASPDSDAELLEAKRVLTILLESCSVKQAANLAAQLTGQKKNTLYQLALELRGDSELS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H011</accession>
    <name>A0A2S9H011_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Efflux transporter, RND family, MFP subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2045</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93307">
        <property type="protein sequence ID" value="PRC93307"/>
        <property type="gene ID" value="S2091_2045"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006143">
        <property type="entry name" value="RND_pump_MFP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01730">
        <property type="entry name" value="RND_mfp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HlyD_D23" evidence="2">
        <location>
            <begin position="78"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="419" mass="43852" checksum="58DF4705B6BAE724" modified="2018-07-18" version="1">MPFTSTTTSNKLHFASQKIVQFVQISCVASMICLLAACSKPVEKVEEVRPVRAVMVGAGSADVLAEFSGELRPRVESRLGFRVAGKIVARKVDVGTVVKRGQLLMQLDGQDLALAQVQSSAGLRAAESSRDLARAELKRYTELRAENFVSQAVLDSKTTAYQGAQASYEQAAAAQKNQSNQSSYGSLLADVDGVVTEIDAEVGQVVAAGTPVVRVAQSGEIDAVIGIPEDKVNAIRNISDVRVRIWANPNSSIAGKLRELSPIADPVTRTYTVKIALPNDVKDIKLGMTAYVTFAAKTATSVLKLPTTALFQDKNVTSVWLVEQGHVRLVPIQVAGSAGEDVLVASGISAGQTVVTAGVNMLKEGQKVQILGAVQAANVTAPVTGSDSTSTPTSAVSVPALHPVAAVTDVFSASAGVTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H015</accession>
    <name>A0A2S9H015_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Phosphotransferase system mannose/fructose-specific component IIA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_2026</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93288">
        <property type="protein sequence ID" value="PRC93288"/>
        <property type="gene ID" value="S2091_2026"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009401">
        <property type="term" value="P:phosphoenolpyruvate-dependent sugar phosphotransferase system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00006">
        <property type="entry name" value="PTS_IIA_man"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.510">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004701">
        <property type="entry name" value="PTS_EIIA_man-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036662">
        <property type="entry name" value="PTS_EIIA_man-typ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033887">
        <property type="entry name" value="PTS_IIA_man"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03610">
        <property type="entry name" value="EIIA-man"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53062">
        <property type="entry name" value="SSF53062"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51096">
        <property type="entry name" value="PTS_EIIA_TYPE_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PTS EIIA type-4" evidence="3">
        <location>
            <begin position="1"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC93288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="135" mass="14448" checksum="1AE358E877AEB39F" modified="2018-07-18" version="1">MVGILIMAHAPLGNAFITAARHVFRCMPEHLEAIDVMPDQNPEEVIQLAKLAIARLNLGNGVLVLTDVCGGTPSNCSQKLDALDQVAVLAGLSLPMLLRALTYRHDNLDVVFEMAQAGAQNGAVRVDNRLRIAPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H060</accession>
    <name>A0A2S9H060_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1756</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93369">
        <property type="protein sequence ID" value="PRC93369"/>
        <property type="gene ID" value="S2091_1756"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="3"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="300" mass="32526" checksum="E7D775FD70B5671A" modified="2018-07-18" version="1">MHLTLRQLQIFMAVAESGSTTAAAELVCLTQSASSAALRELENLLSCHLFDRVGKRLILNDNGRQLLPQARLMLDAAANIEQQFLPGTSANISGLKIGSSTTIGIYLLPSILAKYDAGLHAQPTKITIANTLDVANLVANFEVDAGFIEGPCHQTDLIIEPWLMDELIIVCSPQHPILAGQGSNKIDLVTLREAGWLLRERGSGTREAVEQALLPQLHFLNPSIEFSNSEAIKYAAAAGLGLACLSRLVVQDLLHSGQLVELSTSLPKLQRHFYLLTAKKKIVSARLAALLEFCRGWTSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H062</accession>
    <name>A0A2S9H062_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Short-chain dehydrogenase of various substrate specificity</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2078</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93340">
        <property type="protein sequence ID" value="PRC93340"/>
        <property type="gene ID" value="S2091_2078"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="222" mass="23436" checksum="4C4F2F432A6D5E9A" modified="2018-07-18" version="1">MPTVLIIGASRGIGLALVQEYHAAGWRVLATARQAADLEKLSTIGATPLPLDVTDLNDCAAIGWRLDDEKIDVAILSAGVIGTRTEGLDTPGADEFNHVMQTNVLAAMRLLPIIAPIVAASNGRLAVISSMMGSLSMRNDASSWLYRASKAALNSVLLDVAHSFPEMVSIAMHPGWVRTEMGGAGATLSGEQSAAGIRATIAARTKQDNGTFYNYDGTQLTW</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H086</accession>
    <name>A0A2S9H086_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1782</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93395">
        <property type="protein sequence ID" value="PRC93395"/>
        <property type="gene ID" value="S2091_1782"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="SSF48208"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="610" mass="65894" checksum="A309C136B5CF4FAF" modified="2018-07-18" version="1">MNKSSQKFGKKYTAGMHDRADELRATRPQLNSIFRKRSLLAMLTGSAILYGCGGGNSPADSSAAAVGKTEARQLAAASSTELTATSSDAGLQSGFNQAVTEARLLNFTDANYPFLLSLGWPTTDSRCAESTMVTGYLAGIQNRCAYYSRDYVHQATGAYYLGMYEQNYQMAYHFATILHNNSGALAPYWAIGANGNEYEQNDESPAPFEIGQNIANMYRLTADSRYLGSAFSAYINNINNNFSNINNNQYINADGFRMARLEDGEAATYNEFVSNAGVPPTTSIVLGGDMAASEIAYYRGVSQYPAMQASGDTTNMAGQFNTLSSNFNSHWYLGGAGHFSVALTGVTGTTYSSANYASLTYYDHYAQEPNLFPLYKGIITDPTALANQATYVDSNAEAAFVAAGNSLQSPGVESHTYLPTAFYNANMPDTAWKWLTRLAAWQVQGGTSTYPEVGFALISDTITKVLGVDFDAPNNNLTTLANLPSSFSSGNYVQVSNIPIHNAALTFSLTISQTAVGTQGLVSTMLAFNTDPSLQPNGGVYWIPRFRTAAGYHCNVFSTFKNGTSRTDTFNLIYDPTTETYGCNADNRGIWLYAGDPNYAVTSMTVTSSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0J2</accession>
    <name>A0A2S9H0J2_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Cbb3-type cytochrome c oxidase subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">S2091_1865</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15 17">
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
        </cofactor>
        <text evidence="15 17">Binds 2 heme C groups per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 15">Energy metabolism; oxidative phosphorylation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="15">Component of the cbb3-type cytochrome c oxidase.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="15">Cell inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 15">Belongs to the CcoP / FixP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93478">
        <property type="protein sequence ID" value="PRC93478"/>
        <property type="gene ID" value="S2091_1865"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00705"/>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070469">
        <property type="term" value="C:respirasome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006811">
        <property type="term" value="P:ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006119">
        <property type="term" value="P:oxidative phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.280.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032858">
        <property type="entry name" value="CcoP_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038414">
        <property type="entry name" value="CcoP_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004678">
        <property type="entry name" value="Cyt_c_oxidase_cbb3_su3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13442">
        <property type="entry name" value="Cytochrome_CBB3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14715">
        <property type="entry name" value="FixP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000006">
        <property type="entry name" value="Cbb3-Cox_fixP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00782">
        <property type="entry name" value="ccoP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 15" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="3 15" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="15" id="KW-0249">Electron transport</keyword>
    <keyword evidence="5 15 17" id="KW-0349">Heme</keyword>
    <keyword evidence="9 15" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="13 15" id="KW-0406">Ion transport</keyword>
    <keyword evidence="12 15 16" id="KW-0408">Iron</keyword>
    <keyword evidence="14 15 18" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 15 16" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11 15" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0677">Repeat</keyword>
    <keyword evidence="15" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="6 18" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 18" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="15" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="7"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="74"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="19">
        <location>
            <begin position="142"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="19">
        <location>
            <begin position="229"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="binding site" description="covalent" evidence="17">
        <location>
            <position position="155"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="17">
        <location>
            <position position="158"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="16">
        <location>
            <position position="159"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="16">
        <location>
            <position position="198"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>2</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="covalent" evidence="17">
        <location>
            <position position="241"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="17">
        <location>
            <position position="244"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="16">
        <location>
            <position position="245"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>2</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="16">
        <location>
            <position position="286"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRNR" id="PIRNR000006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR000006-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PIRSR" id="PIRSR000006-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="PRC93478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="318" mass="34539" checksum="2374D33782727E8C" modified="2018-07-18" version="1">MSDFTSGFWNIYITVLALLGIAGCALLLWMQSSQKVTGAGDASDSSLNGEASVGTTGHVWDEDLTELNTPMPRWWMWLFYITIVFGLIYLFLYPGLGSYAGKLGWKSSGAYQEELLKAEAEYGPLFNKYLKQDLKTVAADPKAHAMGERLFLTYCSQCHGSDARGSKGFPNLTDHDWLFGGDPETIKTTIMNGRNGLMPPMGAAVGTDKDVENVAHYVLSLSGSTADPIKAAFGKPKFANCAGCHGSDGAGNQMIGAPNLTDKIWLFGGSKETIMETIQHGRSSTMPPFKDFLGEPKVHVLAAYVWSLSNVNQDLPQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H190</accession>
    <name>A0A2S9H190_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Ubi-OHases: ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_1361</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; ubiquinone biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the UbiH/COQ6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93752">
        <property type="protein sequence ID" value="PRC93752"/>
        <property type="gene ID" value="S2091_1361"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00232"/>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016709">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006744">
        <property type="term" value="P:ubiquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018168">
        <property type="entry name" value="Ubi_Hdrlase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010971">
        <property type="entry name" value="UbiH/COQ6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01988">
        <property type="entry name" value="Ubi-OHases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01304">
        <property type="entry name" value="UBIH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0274">FAD</keyword>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0830">Ubiquinone</keyword>
    <feature type="domain" description="FAD_binding_3" evidence="8">
        <location>
            <begin position="5"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC93752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="380" mass="41227" checksum="41FF9FB5F6725327" modified="2018-07-18" version="1">MMPKFDIAICGAGPVGQTLALLLIKRGIPASNLVLIDAKTQEQAAADQRTIALSYGSQQILQAASAWPIKATEIHQIHVSRRGHFGRTVIDCKDQKVPALGYVARYANILQPLTTALNQHPELTFLRPAKVSTITQTENHAQIILEDQRIIDAKIVVQAEGGLFGEQAPQIRHHDYQQTALIAHVTTSSPIAARAFERFTEQGPLALLPQEDGYALVWCVRPEHAARLIILSDAAFLAELQTTFGERLGRFISSSPRSAFPLGLNAQTSAPTGRTISIGNAAQTLHPVAGQGLNLGLRDAFQLAQFLSKSTAPTALQDFFQTRLADRNSTIHLTDQMAQVFASAPDGSAKQTLLGAGLGLIDLFAPAQHWLAQQMMFGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1A9</accession>
    <name>A0A2S9H1A9_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribose-phosphate pyrophosphokinase</fullName>
            <shortName evidence="6">RPPK</shortName>
            <ecNumber evidence="6">2.7.6.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">5-phospho-D-ribosyl alpha-1-diphosphate</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Phosphoribosyl diphosphate synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Phosphoribosyl pyrophosphate synthase</fullName>
            <shortName evidence="6">P-Rib-PP synthase</shortName>
            <shortName evidence="6">PRPP synthase</shortName>
            <shortName evidence="6">PRPPase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">prs</name>
        <name evidence="8" type="ORF">S2091_1383</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>ATP + D-ribose 5-phosphate = 5-phospho-alpha-D-ribose 1-diphosphate + AMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15609"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.7.6.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="6">Binds 2 Mg(2+) ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="6">Metabolic intermediate biosynthesis; 5-phospho-alpha-D-ribose 1-diphosphate biosynthesis; 5-phospho-alpha-D-ribose 1-diphosphate from D-ribose 5-phosphate (route I): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homohexamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.6.1" evidence="6"/>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93774">
        <property type="protein sequence ID" value="PRC93774"/>
        <property type="gene ID" value="S2091_1383"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00087">
        <property type="reaction ID" value="UER00172"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004749">
        <property type="term" value="F:ribose phosphate diphosphokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006015">
        <property type="term" value="P:5-phosphoribose 1-diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009165">
        <property type="term" value="P:nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009156">
        <property type="term" value="P:ribonucleoside monophosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00583_B">
        <property type="entry name" value="RibP_PPkinase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000842">
        <property type="entry name" value="PRib_PP_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029099">
        <property type="entry name" value="Pribosyltran_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRibTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005946">
        <property type="entry name" value="Rib-P_diPkinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037515">
        <property type="entry name" value="Rib-P_diPkinase_bac"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10210">
        <property type="entry name" value="PTHR10210"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14572">
        <property type="entry name" value="Pribosyl_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13793">
        <property type="entry name" value="Pribosyltran_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01251">
        <property type="entry name" value="ribP_PPkin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00114">
        <property type="entry name" value="PRPP_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6 8" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 6" id="KW-0545">Nucleotide biosynthesis</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pribosyltran_N" evidence="7">
        <location>
            <begin position="6"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Ribose-5-phosphate binding" evidence="6">
        <location>
            <begin position="225"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="195"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="39"/>
            <end position="41"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="98"/>
            <end position="99"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="133"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="172"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="197"/>
        </location>
        <ligand>
            <name>D-ribose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="221"/>
        </location>
        <ligand>
            <name>D-ribose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF13793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC93774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="316" mass="34125" checksum="C15A62A7A106EDE1" modified="2018-07-18" version="1">MAHDNLMVFTGNANPALAAGVAKQLGLSLGKAVVSKFSDGEITVEINENVRGKDVFIIQSTCVPTNDSLMELMLMVDALKRASAGRITAAIPYFGYARQDRRPRSARVAISAKVVANMLEEVGVERVIIMDLHADQIQGFFDIPVDNIYASPILLRDLIAKNYDDLLVVSPDVGGVVRARALAKHLNCDLAIIDKRRPKANVSEVMNIIGEVEGRNCVIMDDMVDTAGTLTKAAEVLKERGAKKVLAYCTHPVLSGPAIQRITDSPLDELVVTDTIPLSAAALNCSKIRQLSCDAILAETIRRITKGDSVISLFAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1C1</accession>
    <name>A0A2S9H1C1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="14">P pilus assembly protein porin PapC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">S2091_1390</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell outer membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the fimbrial export usher family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93781">
        <property type="protein sequence ID" value="PRC93781"/>
        <property type="gene ID" value="S2091_1390"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015473">
        <property type="term" value="F:fimbrial usher porin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009297">
        <property type="term" value="P:pilus assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2070">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2610">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000015">
        <property type="entry name" value="Fimb_usher"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042186">
        <property type="entry name" value="FimD_plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025949">
        <property type="entry name" value="PapC-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043142">
        <property type="entry name" value="PapC-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025885">
        <property type="entry name" value="PapC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037224">
        <property type="entry name" value="PapC_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30451">
        <property type="entry name" value="PTHR30451"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13953">
        <property type="entry name" value="PapC_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13954">
        <property type="entry name" value="PapC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00577">
        <property type="entry name" value="Usher"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141729">
        <property type="entry name" value="SSF141729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 11" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1134">Transmembrane beta strand</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015573193" evidence="11">
        <location>
            <begin position="40"/>
            <end position="909"/>
        </location>
    </feature>
    <feature type="domain" description="PapC_N" evidence="13">
        <location>
            <begin position="68"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="domain" description="PapC_C" evidence="12">
        <location>
            <begin position="825"/>
            <end position="889"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="647"/>
            <end position="669"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF13953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF13954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="PRC93781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="909" mass="97634" checksum="7354B4E05357BD9D" modified="2018-07-18" version="1">MNANKLSNSFLSMHNAKSQKTIPASLLVMGLLSALPADAMIEAATEVASQEFAAPMQVAVATTAAAYNFNSNLLVGGSLSGASLERFNRPNIIDPGNYLVDIYVNNVLSVRKTVEFLVGDQGKVYPCLDDQLLIDSGVKPENISQITSTTTVTTTTTVNDQTKTSTAIKEPAKCYPVEQRISGATSTFLMSSLRLNITVPQALMIRNPRGYVNPENLDAGETMAFFNYDSNYYRYDTQSNNNDSAYLGVNSGINLGMWRLRYQGNYNYQKSSNAPNSTAHWNSSRTYAQRSLPNWQSELTIGQNYTGGNLFSSVGFRGISIATDDRMLPDSMNGYAPIVRGIALTNAKVVIRQAGHEIYQTTVAPGPFIIEDLYPTSYQGDLQVEVTEADGRVAHFTVPFSAVPESMRPGASRYAVSFGQVNQVANMQPFFADATYQRGLTNSLTGNVGVRLAADYQSVLAGAVMGTPVGALGLNTIYSMSKDINNEKLKGWRLATTYSYTYQPTSTTLSLAGYRYSTGGYRDLVDALGVRSAAQTGQIWSSATYQQRNQFVVNLNQNLGRYGQFYVSAAMNDYYAGKENDTQFQLGYSNNYRSINYNLSVSRQQTGLLLNSINGQPGFNNGLQNNATTNMVTLSVSVPLGTGANTSSLSSSVTSQSGGKNSYQTSLSGTIGEDQTTSYGLSTAYQQGSSVSANANVQKQFSAATVGASYSTGKDYWQAGANMRGALVAHSGGLTMGPYVGDTFGLIEAKGAEGALVRNGMGARIDSSGYAVIPYLTPYRYNEVSLDSDGINSNAELAGNQLRAAPYAGASVKFKFETTLGRAVLIKTTLPDGKLLPLGSNVYASDGANVGMVGQGGKIYARAANDQGLLTVKWGNDNELQCTIPYDLTDQKKTNEPLFRLNAACVPAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1C5</accession>
    <name>A0A2S9H1C5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="12">TonB family C-terminal domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">S2091_1394</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
            <orientation evidence="1">Periplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TonB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93785">
        <property type="protein sequence ID" value="PRC93785"/>
        <property type="gene ID" value="S2091_1394"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008756">
        <property type="entry name" value="Peptidase_M56"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006260">
        <property type="entry name" value="TonB/TolA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037682">
        <property type="entry name" value="TonB_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05569">
        <property type="entry name" value="Peptidase_M56"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03544">
        <property type="entry name" value="TonB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01352">
        <property type="entry name" value="tonB_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="50"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="85"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="112"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M56" evidence="11">
        <location>
            <begin position="36"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_C" evidence="10">
        <location>
            <begin position="350"/>
            <end position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF03544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF05569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PRC93785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="429" mass="46726" checksum="BE22CD7DE167A3E8" modified="2018-07-18" version="1">MNSAFNYTLNQLVSVLGSALVNFVWQGVLIGLITAALMVLLRNAKPQTRYAIACAALGLCILLPLQAVIFDSADNATMRILDDSIGLTAGGALAAVDIPIVWTWAQTHLMELVSIWALCVVFFSIRLTVGLAWVSRICDASHNTVNSYWQTRLNNLSQRSGIKHFVPLHVVNNLDTPAVAGWLRPIVLVPASLISGMPPELLEALLAHEVAHIRRMDYAVNLVQSAVEILLFYHPAVWFISGKIRIEREQIADDMAAILIGEPRRLAFALSELEQLKFLTAQLAPAANGGNLVGRIKRLMRPDVRTVGWQSLIPAVSLVLASVAFYANAAPASAATKTTRATLDFERCDKPDYPLQSIQSKEQGTVRILFSIDAKGHVVESKVTKSSGHSMLDSAAVTGLTKCSFRPATHNGKPVSATEMVDYVWTLPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1E5</accession>
    <name>A0A2S9H1E5_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Formamidopyrimidine-DNA glycosylase</fullName>
            <shortName evidence="15">Fapy-DNA glycosylase</shortName>
            <ecNumber evidence="15">3.2.2.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">DNA-(apurinic or apyrimidinic site) lyase MutM</fullName>
            <shortName evidence="15">AP lyase MutM</shortName>
            <ecNumber evidence="15">4.2.99.18</ecNumber>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="primary">mutM</name>
        <name evidence="15" type="synonym">fpg</name>
        <name evidence="19" type="ORF">S2091_1379</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14 15">
            <text>2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'-deoxyribonucleotide-DNA = a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + a 5'-end 5'-monophospho-2'-deoxyribonucleoside-DNA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:66592"/>
            <dbReference type="Rhea" id="RHEA-COMP:13180"/>
            <dbReference type="Rhea" id="RHEA-COMP:16897"/>
            <dbReference type="Rhea" id="RHEA-COMP:17067"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:136412"/>
            <dbReference type="ChEBI" id="CHEBI:157695"/>
            <dbReference type="ChEBI" id="CHEBI:167181"/>
            <dbReference type="EC" id="4.2.99.18"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 15">
            <text>Hydrolysis of DNA containing ring-opened 7-methylguanine residues, releasing 2,6-diamino-4-hydroxy-5-(N-methyl)formamidopyrimidine.</text>
            <dbReference type="EC" id="3.2.2.23"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="15">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 15">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 15">Belongs to the FPG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.2.23" evidence="15"/>
    <dbReference type="EC" id="4.2.99.18" evidence="15"/>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93770">
        <property type="protein sequence ID" value="PRC93770"/>
        <property type="gene ID" value="S2091_1379"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140078">
        <property type="term" value="F:class I DNA-(apurinic or apyrimidinic site) endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008534">
        <property type="term" value="F:oxidized purine nucleobase lesion DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00103">
        <property type="entry name" value="Fapy_DNA_glycosyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015886">
        <property type="entry name" value="DNA_glyclase/AP_lyase_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015887">
        <property type="entry name" value="DNA_glyclase_Znf_dom_DNA_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020629">
        <property type="entry name" value="Formamido-pyr_DNA_Glyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012319">
        <property type="entry name" value="FPG_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035937">
        <property type="entry name" value="MutM-like_N-ter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010979">
        <property type="entry name" value="Ribosomal_S13-like_H2TH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000214">
        <property type="entry name" value="Znf_DNA_glyclase/AP_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010663">
        <property type="entry name" value="Znf_FPG/IleRS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01149">
        <property type="entry name" value="Fapy_DNA_glyco"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06831">
        <property type="entry name" value="H2TH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06827">
        <property type="entry name" value="zf-FPG_IleRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00898">
        <property type="entry name" value="Fapy_DNA_glyco"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01232">
        <property type="entry name" value="H2TH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46946">
        <property type="entry name" value="SSF46946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81624">
        <property type="entry name" value="SSF81624"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00577">
        <property type="entry name" value="fpg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51068">
        <property type="entry name" value="FPG_CAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01242">
        <property type="entry name" value="ZF_FPG_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51066">
        <property type="entry name" value="ZF_FPG_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 15" id="KW-0227">DNA damage</keyword>
    <keyword evidence="10 15" id="KW-0234">DNA repair</keyword>
    <keyword evidence="9 15" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="13 15" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="7 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11 15" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12 15" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 15" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 15 16" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="FPG_CAT" evidence="18">
        <location>
            <begin position="2"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="domain" description="FPG-type" evidence="17">
        <location>
            <begin position="239"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with DNA" evidence="15">
        <location>
            <position position="2"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="15">
        <location>
            <position position="3"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor; for beta-elimination activity" evidence="15">
        <location>
            <position position="58"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor; for delta-elimination activity" evidence="15">
        <location>
            <position position="263"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="91"/>
        </location>
        <ligand>
            <name>DNA</name>
            <dbReference type="ChEBI" id="CHEBI:16991"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="109"/>
        </location>
        <ligand>
            <name>DNA</name>
            <dbReference type="ChEBI" id="CHEBI:16991"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="154"/>
        </location>
        <ligand>
            <name>DNA</name>
            <dbReference type="ChEBI" id="CHEBI:16991"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00024490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="PRC93770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="273" mass="30447" checksum="E2FC62B01873D589" modified="2018-07-18" version="1">MPELPEVEVTRLGVSPYLVEQRVTGLVLRRAGLRWPFPADLAQKVVGQTVQSTGRRGKYLLIVFKKGTLIIHLGMSGHIRILPIHTPAQLHDHMDIVLGEQLLRLTDPRRFGAVLWHDAADGAIEQYPLLQRLGMEPLTEQFNGAVLYTATRHRKIAVKQMLLAGDVVVGVGNIYASESLFISGINPYTPSSELTLARYKKLALAIQKILADAITKGGSSLRDFVGVDGQSGYFQQNYYVYDRTGLPCRKCNTLIQQVKQGQRSTFYCVKCQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1G2</accession>
    <name>A0A2S9H1G2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ABC-type Na+ transport system ATPase component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_1399</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93790">
        <property type="protein sequence ID" value="PRC93790"/>
        <property type="gene ID" value="S2091_1399"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-1278">Translocase</keyword>
    <feature type="domain" description="ABC transporter" evidence="7">
        <location>
            <begin position="2"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="47"/>
            <end position="54"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC93790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="267" mass="28964" checksum="672EB5D982147B89" modified="2018-07-18" version="1">MIRVENLSKHFIRQASGRWQRGKGEVVQAVKDISFCAEDGQITGLLGANGAGKTTTLRMIGALLKQDGGHILVDGVAVQAGQQATQAQMGVLSDARGLYPRLSARENIVYYGVLHGMSREQAHQRVDVLAEVLELKPILERRCDGFSQGEKMKTALARALVHDPKNIILDEPTNGLDVLATRALREFLRWLRSPAGGSKCIIFSTHIMQEVERLCDHVVVVAHGKTVAQGSVAALLSQVGATDFEDAFVKLAFDQSAEPSIQTRSAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1I2</accession>
    <name>A0A2S9H1I2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1453</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93844">
        <property type="protein sequence ID" value="PRC93844"/>
        <property type="gene ID" value="S2091_1453"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="48" mass="5858" checksum="7F42334A40479166" modified="2018-07-18" version="1">MPTKEQVRHYMHERQAEKMPPPSTDEIRRRLGWDLILDSRIIKIKTQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1I6</accession>
    <name>A0A2S9H1I6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cation/multidrug efflux pump</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1437</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93828">
        <property type="protein sequence ID" value="PRC93828"/>
        <property type="gene ID" value="S2091_1437"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2090.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027463">
        <property type="entry name" value="AcrB_DN_DC_subdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001036">
        <property type="entry name" value="Acrflvin-R"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32063">
        <property type="entry name" value="PTHR32063"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00873">
        <property type="entry name" value="ACR_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00702">
        <property type="entry name" value="ACRIFLAVINRP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82714">
        <property type="entry name" value="SSF82714"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="337"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="360"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="431"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="463"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="529"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="853"/>
            <end position="872"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="905"/>
            <end position="931"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="952"/>
            <end position="971"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="983"/>
            <end position="1008"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="1038" mass="111757" checksum="AC07E0A6AA6ECBE2" modified="2018-07-18" version="1">MNISSPFIRRPIATTLLTIGVALAGIVGFSLLPVSPMPSVDFPVISVSAGIPGASPEIMATTVATPLERSLGRIAGINEMTSSSSLGSTSITLQFDLSRDIDGAARDVQAAIAAARVDLPVTLKTNPTYRKVNPSDAPIMILALTSDTMNQGQMYDIASTTMQQKLSQVEGIGQVIVGGSALPAVRIELNPLTLNKYGIGLEQVRTAITSTNANTPKGTVEEGDKQWQIFTNDQAKKAVDYIPLIVGYKNNNPIHLSDIGNVVNSVEDVRNAGSADGKPAVLLILFKQPNANIIETVDRIRSVLPQLKASIPSSIDMTETLDQTTTIRASLHDVERTLAISIGLVILVVFLFLRNVRASIIPSVAVPISLLGTFGIMYLCGYSLDNFSLMALTVSTGFVVDDAIVVLENISRHIEDGMTPWQATLRGAREVGFTVLSMSISLVAVFIPMLFMGGIIGRIFHEFAVTLSVAVLVSLVVSISTTPMMCARLLKPHNEQKHGRIYQASERAFVWLQQKYANGLDVALRHSRITLLTMFAVIGLNVFLFTKVPGGLFPSQDTGMIMGSIVADQATSFQAMLPKLSAYIDVVKADPAVKHVVGFTGGSQTNSGRMFITLKPLDERKISADNVINRLRGKLAAIPGATLFLQARQDIRVGGRSGNALYQYTLQGDDLKELDKWSPKVLRALQDLPQLADVNSTQQDKGLQVTLSIDRPTALRMGVTQTKIDAALYDAFGQRQVSVIYEARNQYHVIMEVSPEYWQRPETLSSIFVTSASGTLVPLSSFATFEPTTTTLNVNHQGQFAATTMSFNLAPGAVLSDAVTAIDAATAKLGLPATIQGSFQGTAKTFQDSLKTMPFLIVASLLTIYIVLGVLYESLVHPITILSTLPSAGVGALLALLLVKMELSMMAFIGIILLIGIVKKNAIMMIDFALVAQRIDKKTPFDAIKQACLQRFRPIMMTTMAALLGAVPLAFGTGTGSELRQPLGVTIIGGLIVSQLLTLFTTPVVYLYMDKLHALGQRIKARRHAHAAPAMPTQIEPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1J7</accession>
    <name>A0A2S9H1J7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1461</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93852">
        <property type="protein sequence ID" value="PRC93852"/>
        <property type="gene ID" value="S2091_1461"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010846">
        <property type="entry name" value="DUF1460"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07313">
        <property type="entry name" value="DUF1460"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="SSF54001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="278" mass="31291" checksum="6ED2AE5EEFF1D4A0" modified="2018-07-18" version="1">MRRVSQLILISSISVGCAPGSGVDEVAQNDETESHQKAKINIDPRTLKKLNILLEERSLNAGISTGQMIDLLSGAFLETPYRANMLQGAVNTPEKLVIDFRGLDCFTYLDYVEALRKSTSQTEFVENVIQTRYVDGDINFLYRKHFFTDWAHREHKLADDITALVSPDIVRVEKYLNKKVDGETYLPGLPVVERSINYIPSEFINDKVISRLQTGDFIGIYTKLAGLDVTHVGFFIMTDNGPVLRNASSRKENEKVVDSPFMDYVAKTPGIIILRAKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1J8</accession>
    <name>A0A2S9H1J8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="9">YscR: type III secretion apparatus protein, YscR/HrcR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_1473</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the FliP/MopC/SpaP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93864">
        <property type="protein sequence ID" value="PRC93864"/>
        <property type="gene ID" value="S2091_1473"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005838">
        <property type="entry name" value="T3SS_IM_P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005773">
        <property type="entry name" value="YopR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30587">
        <property type="entry name" value="PTHR30587"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00813">
        <property type="entry name" value="FliP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01302">
        <property type="entry name" value="TYPE3IMPPROT"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01102">
        <property type="entry name" value="yscR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01060">
        <property type="entry name" value="FLIP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01061">
        <property type="entry name" value="FLIP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="46"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="159"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="195"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006257"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC93864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="222" mass="24344" checksum="17E63AEF5DE14097" modified="2018-07-18" version="1">MSNDISLIGLLALATLLPFLLAAGTCYLKFSIVFVMVRNAMGLQQVPSNLVLNAVALMMSVFVMLPVSQKIYDYQSENPVNFSSLASVESFVDNGLDSYRGYLQKYSDPELTAFFEKIQAARLAEKNTPHLEGEDQVSIFSLLPAYALSEIKSAFKIGFYLYLPFVVIDLVISSILLALGMMMMSPVVISVPIKLILFVAMDGWSLLSQGLILQYIDLGSGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1V9</accession>
    <name>A0A2S9H1V9_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Peptidoglycan lytic exotransglycosylase</fullName>
            <ecNumber evidence="2">4.2.2.n1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Murein hydrolase A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_1106</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Exolytic cleavage of the (1-&gt;4)-beta-glycosidic linkage between N-acetylmuramic acid (MurNAc) and N-acetylglucosamine (GlcNAc) residues in peptidoglycan, from either the reducing or the non-reducing ends of the peptidoglycan chains, with concomitant formation of a 1,6-anhydrobond in the MurNAc residue.</text>
            <dbReference type="EC" id="4.2.2.n1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.2.n1" evidence="2"/>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC93933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93933">
        <property type="protein sequence ID" value="PRC93933"/>
        <property type="gene ID" value="S2091_1106"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019867">
        <property type="term" value="C:outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009254">
        <property type="term" value="P:peptidoglycan turnover"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14485">
        <property type="entry name" value="mltA_like_LT_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010611">
        <property type="entry name" value="3D_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026044">
        <property type="entry name" value="MltA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034654">
        <property type="entry name" value="MltA_3D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005300">
        <property type="entry name" value="MltA_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036908">
        <property type="entry name" value="RlpA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30124">
        <property type="entry name" value="PTHR30124"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06725">
        <property type="entry name" value="3D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03562">
        <property type="entry name" value="MltA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF019422">
        <property type="entry name" value="MltA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00925">
        <property type="entry name" value="MltA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50685">
        <property type="entry name" value="SSF50685"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015611084" description="Peptidoglycan lytic exotransglycosylase" evidence="6">
        <location>
            <begin position="25"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="domain" description="MltA" evidence="7">
        <location>
            <begin position="144"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00030918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC93933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="413" mass="45229" checksum="494D661C7558D3CD" modified="2018-07-18" version="1">MFKINRSVPSLAALLLLAACQTTVVEPINKPTPPVATIPAVTPPVSVIESKPQNLKASFKQLDYSDLPGWNQDNLNEAWPAFKASCKALINKSDWHELCTIAQTVDGTDSSGVRSFFEAFFNPYQVINPDGTESGLITGYYEPLLRGSRQRGGSYQTPLYQAPSDLLTIDMAGLYPELKGMRLRGRVVGNKVVPYPSRAELLQPGVLTGKEICWVDDSVDAFFLQVQGSGRIFFADTNETVRLAYADQNGQPYKSIGRYLVDKGELKLEQASAQGIKNWIANNPTRENEVLNANPSYVFFKEEKISDPMQGPKGALGVALSEKRSVAIDAQFLPLGAPVFINTTEPNTDVPLKRLMMAQDTGGAIRGAVRADFFWGFGAQAGDMAGRMKQRGMLWVLWPKLASAPLGVVVNQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H272</accession>
    <name>A0A2S9H272_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Peptidase_M78 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1216</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94043">
        <property type="protein sequence ID" value="PRC94043"/>
        <property type="gene ID" value="S2091_1216"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010359">
        <property type="entry name" value="IrrE_HExxH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06114">
        <property type="entry name" value="Peptidase_M78"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_M78" evidence="1">
        <location>
            <begin position="91"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="219" mass="24739" checksum="BFD73F2E61C4A8E9" modified="2018-07-18" version="1">MQAAFRRSREEQSDVGAISAWLRMGEQDAEKLDGDKFNRTKYIAALTEIRKLTVLPPEQFEPLLREYFKSAGVAFVIVPAIPKAHVSGVARWLNPHRPLIQLSLYGKTNDKFWFTLFHEAAHVLLHGNEKKSVYLDDPTKTGNASAAEREANEWAGHFLIPQQHTLQLPELRTKAAVIHFANSIGIHPGIVVGRLQHDGIIDPSWMNDLRMSFRLNAAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H274</accession>
    <name>A0A2S9H274_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Enoyl-CoA hydratase/carnithine racemase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1252</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the enoyl-CoA hydratase/isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94079">
        <property type="protein sequence ID" value="PRC94079"/>
        <property type="gene ID" value="S2091_1252"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.12.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018376">
        <property type="entry name" value="Enoyl-CoA_hyd/isom_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014748">
        <property type="entry name" value="Enoyl-CoA_hydra_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00166">
        <property type="entry name" value="ENOYL_COA_HYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="260" mass="28154" checksum="D15882E6639D9524" modified="2018-07-18" version="1">MSDYTNLQLEIEGHTALVTLTNPSANTFTRDGLMALTQLVHDLNARRDVVSLVITGQGEKFFSAGADLKQFADGDKAMAREMARRFGEAFEALSQFRGVSIAAINGYAMGGGLECALACDIRIAESQAQMALPEASVGLLPCAGGTQNLAWLVGEGWAKRMVLLGERINADTALRIGLIEEITKTGEARARALELAKMTDKQSPTSIAACKKLIQGARHAPLAHMLPLEREAFIDLFDSYDQQEGVNAFLQKRPARWSNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2B2</accession>
    <name>A0A2S9H2B2_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">30S ribosomal protein S5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">rpsE</name>
        <name evidence="12" type="ORF">S2091_1298</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 8">Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.</text>
    </comment>
    <comment type="function">
        <text evidence="8">With S4 and S12 plays an important role in translational accuracy.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.</text>
    </comment>
    <comment type="domain">
        <text evidence="8">The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8 10">Belongs to the universal ribosomal protein uS5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94125">
        <property type="protein sequence ID" value="PRC94125"/>
        <property type="gene ID" value="S2091_1298"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01307_B">
        <property type="entry name" value="Ribosomal_S5_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000851">
        <property type="entry name" value="Ribosomal_S5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005712">
        <property type="entry name" value="Ribosomal_S5_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005324">
        <property type="entry name" value="Ribosomal_S5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013810">
        <property type="entry name" value="Ribosomal_S5_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018192">
        <property type="entry name" value="Ribosomal_S5_N_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13718">
        <property type="entry name" value="PTHR13718"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00333">
        <property type="entry name" value="Ribosomal_S5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03719">
        <property type="entry name" value="Ribosomal_S5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01021">
        <property type="entry name" value="rpsE_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00585">
        <property type="entry name" value="RIBOSOMAL_S5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50881">
        <property type="entry name" value="S5_DSRBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 8 9" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="6 8 9" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5 8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 8" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="S5 DRBM" evidence="11">
        <location>
            <begin position="17"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01307"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PRC94125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="172" mass="18127" checksum="BA607F44AEB1D43A" modified="2018-07-18" version="1">MAKMQAKTASDKPDDGMREKMIAINRVTKVVKGGRIMGFAALTVVGDGDGRIGMGKGKSKEVPVAVQKAMEEARRKMIKVTLKNGTLQHTVTGQHGASKVMIMPAKEGTGVIAGGPMRAIFEVMGIVNVVAKSNGSTNPYNMVRATLDGLSKMSTPSEIAAKRGKSVEEILG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2D0</accession>
    <name>A0A2S9H2D0_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">50S ribosomal protein L4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rplD</name>
        <name evidence="7" type="ORF">S2091_1314</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Forms part of the polypeptide exit tunnel.</text>
    </comment>
    <comment type="function">
        <text evidence="5">One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the universal ribosomal protein uL4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94141">
        <property type="protein sequence ID" value="PRC94141"/>
        <property type="gene ID" value="S2091_1314"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1370.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01328_B">
        <property type="entry name" value="Ribosomal_L4_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002136">
        <property type="entry name" value="Ribosomal_L4/L1e"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023574">
        <property type="entry name" value="Ribosomal_L4_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013005">
        <property type="entry name" value="Ribosomal_uL4/L1e"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10746">
        <property type="entry name" value="PTHR10746"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00573">
        <property type="entry name" value="Ribosomal_L4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52166">
        <property type="entry name" value="SSF52166"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03953">
        <property type="entry name" value="rplD_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0699">rRNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="48"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="48"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00019302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC94141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="207" mass="22996" checksum="415C6E8CF936083E" modified="2018-07-18" version="1">MELKLLNDQGQTASNVAAPDTIFARDYNEALIHQVVVAFQANARSGNRKQLGRDDVHHTTKKPWRQKGTGRARAGMSSSPLWRGGGRAFPNSPDENFSQKINKKMYRAGICSILSQLAREGRLSVVEEFAVDAPKTKLLSDKLKTMGCLDSVLIIADEFNENLMLASRNLPNVLIVEPRYADPVSLVFFKKILITKLALAKIEEMLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2F0</accession>
    <name>A0A2S9H2F0_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5 7">50S ribosomal protein L15</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rplO</name>
        <name evidence="10" type="ORF">S2091_1296</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Binds to the 23S rRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the universal ribosomal protein uL15 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94123">
        <property type="protein sequence ID" value="PRC94123"/>
        <property type="gene ID" value="S2091_1296"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01341">
        <property type="entry name" value="Ribosomal_L15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036227">
        <property type="entry name" value="L18e/L15P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030878">
        <property type="entry name" value="Ribosomal_L15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005749">
        <property type="entry name" value="Ribosomal_L15_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001196">
        <property type="entry name" value="Ribosomal_L15_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021131">
        <property type="entry name" value="Ribosomal_L18e/L15P"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12934">
        <property type="entry name" value="PTHR12934"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00828">
        <property type="entry name" value="Ribosomal_L27A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52080">
        <property type="entry name" value="SSF52080"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01071">
        <property type="entry name" value="rplO_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00475">
        <property type="entry name" value="RIBOSOMAL_L15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_L18e/L15P" evidence="9">
        <location>
            <begin position="28"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00029547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01341"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC94123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="143" mass="15057" checksum="3D06989534733D3A" modified="2018-07-18" version="1">MELNSIQPADGAKHYKRRVGRGIGSGLGKTSGRGHKGQKSRTGGFHKVGFEGGQMPLQRRLPKRGFKSLATPFKAEVRLSQLDSLPIAEIDMLALKQAGMVPELARVVRVILSGSITKKVTLTGLIVTKGAKAAIEAAGGSVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2I2</accession>
    <name>A0A2S9H2I2_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Energy-dependent translational throttle protein EttA</fullName>
            <ecNumber evidence="10">3.6.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Translational regulatory factor EttA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">ettA</name>
        <name evidence="13" type="ORF">S2091_1340</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>ATP + H2O = ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="10">Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="10">Associates with ribosomes and polysomes.</text>
    </comment>
    <comment type="domain">
        <text evidence="10">The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.</text>
    </comment>
    <comment type="domain">
        <text evidence="10">The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.-" evidence="10"/>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94167">
        <property type="protein sequence ID" value="PRC94167"/>
        <property type="gene ID" value="S2091_1340"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045900">
        <property type="term" value="P:negative regulation of translational elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00847">
        <property type="entry name" value="EttA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032781">
        <property type="entry name" value="ABC_tran_Xtn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022374">
        <property type="entry name" value="EttA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43858">
        <property type="entry name" value="PTHR43858"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12848">
        <property type="entry name" value="ABC_tran_Xtn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03719">
        <property type="entry name" value="ABC_ABC_ChvD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 10 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0677">Repeat</keyword>
    <keyword evidence="10" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 10" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="7 10" id="KW-0810">Translation regulation</keyword>
    <keyword evidence="8" id="KW-1278">Translocase</keyword>
    <keyword evidence="3 10" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="ABC transporter" evidence="12">
        <location>
            <begin position="6"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="12">
        <location>
            <begin position="324"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="region of interest" description="Arm" evidence="10">
        <location>
            <begin position="95"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="PtIM" evidence="10">
        <location>
            <begin position="242"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="39"/>
            <end position="46"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10 11">
        <location>
            <begin position="356"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PRC94167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="555" mass="61451" checksum="91F5DC1748D34CA1" modified="2018-07-18" version="1">MAHYVFTMNKVGKIVPPKRQILKDISLSFFPGAKIGVLGLNGSGKSTLLKIMAGIDKDIQGEAVPMPNLNIGYLPQEPLLDPEQTVREAVESALGEVFAAKAKLEAVYAAYGEEDADFDALANEQARLEAIISTASGDNVELQLEMAADALRLPAWDAKIGVLSGGEKRRVALCRLLLSKPDMLLLDEPTNHLDAESVDWLEQFLLRFPGTVVAITHDRYFLDNAAEWILELDRGHGIPWKGNYSSWLDQKQARLKQEESTESARQKALQKELEWSRQNPKARQAKSKARLARFNELSEHEYQKRNETQEIFIPVAERLGNDVIEFKNVTKSFGDRLLIDNLSFTVPAGAIVGIIGPNGAGKSTLFKMIVGREQPDSGEVAVGQTAKVSLVDQTREDLGNTKTVFEDVCGGADILTVGRFEMASRAYLGRFNFKGGDQQKIVGNLSGGERGRLHLAKTLLQGGNVLLLDEPSNDLDVETLRALEDALLEFAGSVMVISHDRWFLDRIATHILAFEGDSQVSFFDGNYQEYEADKKKRLGEEGAKPRRIRYKPLAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2I3</accession>
    <name>A0A2S9H2I3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0813</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94192">
        <property type="protein sequence ID" value="PRC94192"/>
        <property type="gene ID" value="S2091_0813"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="130" mass="14010" checksum="2D24C9DECB8C0C16" modified="2018-07-18" version="1">MRASTSKFAHFKLVFGLFLLGLMLSATSYAIDRPLPVNAKLGTFSPSANPAIVIDGNVRQLTAGAQIRNHHNVIVQPMSLSGPDVQILYKENSQGQIERIWILTKDEVQAYSAGPQPATPLPSPTPTSAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2R4</accession>
    <name>A0A2S9H2R4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">GGDEF: diguanylate cyclase (GGDEF) domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_0868</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94247">
        <property type="protein sequence ID" value="PRC94247"/>
        <property type="gene ID" value="S2091_0868"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015522772" evidence="3">
        <location>
            <begin position="31"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="439"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="199"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="4">
        <location>
            <begin position="516"/>
            <end position="654"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC94247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="696" mass="77322" checksum="DEE278804822A08F" modified="2018-07-18" version="1">MQIHLDRFSSLRACLAGLVLLCLFVGTTQAVDPQPSPIQSEIFRLQDLSETQVAESIKQLSELKRSLPADTALEDQREALIALIGLYLNDDQNEPAGKLNAELNALGQRYHDNWSNAMVLNFQAAILRGEGKLQEAKKVNAQAMQLAKIVNVKRLTSRVNSTASVINSALGDFQIALQYQLAAMDALEEGSRHDDLQLINALNNIGNLYLSLKDPQMALEYYSKGTRLAEKMDDQIMLGMLAGNRGYAYSTQGKLTDAIKAYTESLAIARQLSDRRSEATALNNLSDAAYRLDNYSLCLQYAKQTLQLVEKIGNSGLKASGLVNLGLCHMGLGEVQLGAGEVNQGIDILRKSNAKPDIESVLGQLATAYEKAGMYRDAYKAIVEELALSTELFQVDRDRAVSELKAKYDASQREKQIEVLEQKNQVQSVEIKNKGLQRIIATLSTIIAIAVALTILFLYRKVRETNRNLEEANVKLAHQSTRDPLTGLLNRRAFHDAMQFRTQITERRSLGTTTPPPHALVMLDIDHFKRINDNYGHAAGDSVLVELSKRLTHVMRDKDMLMRWGGEEFLVFLNHIPTANLPQVVERILISVGGRQVPFENNTMPVTISAGYISLQQGDTSEVDPNWEKMLNLADSALYMAKTRGRNQAIGIKVVNVKKEEFDALLEGDLENSIKQGKVIIEQIAGPEQHEAMVEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2S9</accession>
    <name>A0A2S9H2S9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Response regulator of the LytR/AlgR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_0910</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94289">
        <property type="protein sequence ID" value="PRC94289"/>
        <property type="gene ID" value="S2091_0910"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007492">
        <property type="entry name" value="LytTR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04397">
        <property type="entry name" value="LytTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00850">
        <property type="entry name" value="LytTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50930">
        <property type="entry name" value="HTH_LYTTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="2"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="domain" description="HTH LytTR-type" evidence="3">
        <location>
            <begin position="145"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC94289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="253" mass="29251" checksum="DABCE0B6EB63E001" modified="2018-07-18" version="1">MRVLIVDDEPLSRRGVRARLLRFSDISVIGECGDGISAVEKIRAENPDLVFLDIQMPGLNGLEVMRQLDQEHLPLVIFLTAYDEHALSAFDVQALDYLVKPIDDERFYVALERARALLETSQRLRSAEKMIEVLKGESSPYATHFRVQTGTRIQIVDAENIDWIAAAGDYCELHVQGRLHLLRETMRSFEECLDPARFIRIHRSRILQKSRVMELRRLENREFLITLVDGSEHRSSRTCADRIDSWLLGRNRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2W2</accession>
    <name>A0A2S9H2W2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">BON domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0943</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94322">
        <property type="protein sequence ID" value="PRC94322"/>
        <property type="gene ID" value="S2091_0943"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007055">
        <property type="entry name" value="BON_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04972">
        <property type="entry name" value="BON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50914">
        <property type="entry name" value="BON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015430302" evidence="1">
        <location>
            <begin position="26"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="domain" description="BON" evidence="2">
        <location>
            <begin position="38"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="108" mass="11473" checksum="87D2D35E508DECAF" modified="2018-07-18" version="1">MMKLKFGTTYLLVGCLLAPMAGAYADNVDNDHPMNLVKDSAITAAIKTKLAAEHLPSLKDIKVDTDDKGVVWLSGSTDTQTSINKAGSIARNTDGVIAVKNQIIVKSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2Z4</accession>
    <name>A0A2S9H2Z4_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Release factor glutamine methyltransferase</fullName>
            <shortName evidence="6">RF MTase</shortName>
            <ecNumber evidence="6">2.1.1.297</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">N5-glutamine methyltransferase PrmC</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Protein-(glutamine-N5) MTase PrmC</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Protein-glutamine N-methyltransferase PrmC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">prmC</name>
        <name evidence="9" type="ORF">S2091_0857</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 6">Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>L-glutaminyl-[peptide chain release factor] + S-adenosyl-L-methionine = H(+) + N(5)-methyl-L-glutaminyl-[peptide chain release factor] + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42896"/>
            <dbReference type="Rhea" id="RHEA-COMP:10271"/>
            <dbReference type="Rhea" id="RHEA-COMP:10272"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30011"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:61891"/>
            <dbReference type="EC" id="2.1.1.297"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.297" evidence="6"/>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94236">
        <property type="protein sequence ID" value="PRC94236"/>
        <property type="gene ID" value="S2091_0857"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102559">
        <property type="term" value="F:protein-(glutamine-N5) methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036009">
        <property type="term" value="F:protein-glutamine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018364">
        <property type="term" value="P:peptidyl-glutamine methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02126">
        <property type="entry name" value="RF_methyltr_PrmC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004556">
        <property type="entry name" value="HemK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040758">
        <property type="entry name" value="PrmC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019874">
        <property type="entry name" value="Release_fac_Glu-N5_MeTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007848">
        <property type="entry name" value="Small_mtfrase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05175">
        <property type="entry name" value="MTS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17827">
        <property type="entry name" value="PrmC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00536">
        <property type="entry name" value="hemK_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03534">
        <property type="entry name" value="RF_mod_PrmC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6 9" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 6 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PrmC_N" evidence="8">
        <location>
            <begin position="20"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="domain" description="MTS" evidence="7">
        <location>
            <begin position="96"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="6">
        <location>
            <begin position="116"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="6">
        <location>
            <begin position="181"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="139"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="166"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="181"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF05175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF17827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC94236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="287" mass="31692" checksum="2FB69FB0BC8798C2" modified="2018-07-18" version="1">MSQHSIANLLNSTTAAGTLPALETRLLMMHVLNKTRIQLITQADYELSDSELNALQLLIDRRVQGEPIAYLIGQREFFGLMLQVTPDVLIPRPDTELLVELGLQYAPPNSTVLDLGTGSGAIAIALAHQRADLQVWACDISQAALAVAQNNAVTHQCKITLLKSDWYAQLPDMQWQTIVSNPPYIVQHDPHLSQGDLRFEPINALTDHADGLSAYRQLIAGAVSRLTEDGWLLLEHGYDQAQAVRALLTEHQFINVQSWCDIAGIERVSVGQRHSIPSPTFLSKIPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2Z5</accession>
    <name>A0A2S9H2Z5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0976</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94355">
        <property type="protein sequence ID" value="PRC94355"/>
        <property type="gene ID" value="S2091_0976"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="123" mass="12419" checksum="0BF4236F9BD6D154" modified="2018-07-18" version="1">MLITRSKKIHGVIHTCAVACAGIGAGLAQVPGSDSAAIVPLQTAMIVSIAAEHGASVSKGLAADLLLTFTATLVGRTASQFLVGWIPVAGNIINASTAASITEVIGWAANAYFEKTEIASKSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H349</accession>
    <name>A0A2S9H349_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HTH cro/C1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1022</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94401">
        <property type="protein sequence ID" value="PRC94401"/>
        <property type="gene ID" value="S2091_1022"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="2">
        <location>
            <begin position="15"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="102"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="133" mass="15057" checksum="959F4B0F41910953" modified="2018-07-18" version="1">MEYPIKTLSQLRLVLQGFRKAAGLTQAAMASQLGITQQSYAQIEANPAVSSMERLYKILRILNVELILAYEPNQKIDQGTFSTPRLEEMNENIEKTLEVEPETVKFSRTTAKKSTSRKAPKRVMPPSAKKESW</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H371</accession>
    <name>A0A2S9H371_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1050</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94429">
        <property type="protein sequence ID" value="PRC94429"/>
        <property type="gene ID" value="S2091_1050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007165">
        <property type="entry name" value="Phage_holin_4_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37309">
        <property type="entry name" value="PTHR37309"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04020">
        <property type="entry name" value="Phage_holin_4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="28"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="89"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="113" mass="12290" checksum="E593C25D0B8D75D9" modified="2018-07-18" version="1">MRLLATWLINALALLALPYLMHSVSIDSFATALLVAVVLGFVNTVLRPILLLLTLPVTVVSLGLFVLVLNGLLFWMVATMFTGFHVAGFWSAVLAAMLYSVISWALSTLILKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3D2</accession>
    <name>A0A2S9H3D2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0497</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94494">
        <property type="protein sequence ID" value="PRC94494"/>
        <property type="gene ID" value="S2091_0497"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002818">
        <property type="entry name" value="DJ-1/PfpI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018062">
        <property type="entry name" value="HTH_AraC-typ_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01965">
        <property type="entry name" value="DJ-1_PfpI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00041">
        <property type="entry name" value="HTH_ARAC_FAMILY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="2">
        <location>
            <begin position="226"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="334" mass="36755" checksum="94905A5DA297121B" modified="2018-07-18" version="1">MLKITSPSTVAVAVVVFDGISPFHLSVPGLVFDTQHEGVDKPSFKVCVCAMEPKAGNHTIRTNAGFTFNIKHGLSILKRADMIVIPSWSSNLDAPPEHLLVELRKAHKRGARIVGLCLGAFVLAEAGLLNQRTATTHWAKASEFTQRYPQITLVPNVLYVDHGDVITSAGTAAGIDCCLHILRSQYGSDIAAHVARKLVIAPHRQGGQAQYIDQPLPVLASDGRLSSVLEWMLQNLGEQQPIDQLAQRALMSRRSFTRHFQKLTGTTVGQWLLNQRLCQAQRQLESTRCSIDDIAIDTGFGSALVLRRHFARTFNTSPSAYRREFQGTETNPVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3R1</accession>
    <name>A0A2S9H3R1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0628</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94625">
        <property type="protein sequence ID" value="PRC94625"/>
        <property type="gene ID" value="S2091_0628"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="48"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="103" mass="11524" checksum="BE4485459D8EBFB7" modified="2018-07-18" version="1">MTKHEKLLDVLHSTAQGLHAAGTMDAMTMREFDALCLTPVQDYSAEQIKRLRLRFKASQAVFAAYLNTSLSTVQKWEQGQKHPNGPSLKLLNIVDRKGLEALT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3X1</accession>
    <name>A0A2S9H3X1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="12">TonB dependent receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">S2091_0687</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94684">
        <property type="protein sequence ID" value="PRC94684"/>
        <property type="gene ID" value="S2091_0687"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039423">
        <property type="entry name" value="TonB-dep_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010917">
        <property type="entry name" value="TonB_rcpt_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32552">
        <property type="entry name" value="PTHR32552"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01156">
        <property type="entry name" value="TONB_DEPENDENT_REC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 12" id="KW-0675">Receptor</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 9" id="KW-0732">Signal</keyword>
    <keyword evidence="3 7" id="KW-0798">TonB box</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015461797" evidence="9">
        <location>
            <begin position="28"/>
            <end position="802"/>
        </location>
    </feature>
    <feature type="domain" description="Plug" evidence="11">
        <location>
            <begin position="56"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="10">
        <location>
            <begin position="257"/>
            <end position="798"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="39"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="39"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PRC94684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="802" mass="88756" checksum="E19FD06AE2640298" modified="2018-07-18" version="1">MKHKYKVTRLSMLISGLFIVASPFAYAVDTTTEVGKVTVQSQDSGQSTSTGLIQAEESPKARSSVDRTYMDKQQGTSNPYQMIGLLPGVNTYDQDGTGLFGGNIRVRGFNSDQLGFTINGAPVNDSGNFAVYPQEYTDSENLCDIYVTQGSTDTEAPHVGATGGNIGMNTCTPEDARRFRVETIIGSHNLRKYYARVDSGKILNDRFKFFISYSKTQVDKFKGEGGADKEHTDFNSKLTLDNGSYIDTAVLYNTAINNNYRSLTKAQIAQYGTNYDFGTQMPVHQPGVNGTAQNDSTYAPNAGISNGPKNLYYAYNINPFDNWLATMNGHFQITPKSAVDVSPYMWYGYGTGGNELQTITEGNASTLLAGGVKDVNKDGDTKDTVYAYEGSVTKTYRPGITTKFTQQFDDQRVMFGYWFERARQQQTAPYSAIAANGVPADLWLNNPTDYLQNQNGSAVEYRNAMTINTGRSLFAQDNINLMQDKLNVQLGARYSGIERNFTNEPSQSSPAFYTLDKEYTSLLPSLGLRYQLDQADSVFFNATKNFKAPGNFSYFNLVSGGSIVNGTYAGGTMRDVPVDKETSWNFDLGYRYTSDKWTFSSSIYYIDFKNRIATSYNPDTDTNTDFNVGDATSKGFELETGYAITKNWSMYASLSYIKSHMDSDIPWTVTSTLPTAGKEFPDTPNWLSGLNLQYTEANWYVFSQAKYTGKRYSTLVNDDSIGGYVTTSAGAGYTFESNNWLKKPTLKFNVNNMFDRNYLSLSSGSGSQFTSNAYAIGNIPASAPSFYVSPPRTFSLTLVADF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H405</accession>
    <name>A0A2S9H405_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">SPFH domain / Band 7 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0666</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94663">
        <property type="protein sequence ID" value="PRC94663"/>
        <property type="gene ID" value="S2091_0666"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001107">
        <property type="entry name" value="Band_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036013">
        <property type="entry name" value="Band_7/SPFH_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01145">
        <property type="entry name" value="Band_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117892">
        <property type="entry name" value="SSF117892"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="domain" description="PHB" evidence="2">
        <location>
            <begin position="322"/>
            <end position="534"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="690" mass="73866" checksum="9A20DE68FF6F584D" modified="2018-07-18" version="1">MEIFDGIFNHVGIIAGIFLLLIAAIFWKSALSLFGVIMVPDDSLGTVTKKFVLFGANRRMPDGQIIALEGEAGYQADTLPPGLHIGLWPWQYIVELVKFQTIPQGKVGVVQACDGKPLQKGRIIAADCDCNLYQDAHAFLKNGGQRGPQMRVVPPGTYRINPLLFTVKMFDAFEVPSGKLGVVEARDGDALGTGRVIAKGVDCDSYQDPKAFFEHGGQRGPQSKVVPPGIYYINPVLFDVQCVSVVDVPDNKVGIVTTSEGKSLAKGEIAGEQIEGHSMYQDADAFLMNGGHKGLQEQVLLAGRYFINPRFATVEIVEMSMVPIANVGVVIAYVGKEGKDVTGDAFKHGNLVSMGEKGVCVTPLDPGKYPINPYTHKVVTVPTANVVLNWATNKTEAHKLDANLSTITVRSADGFKFNLDVSQIIHIPSKDAPKVIARFGDMSALVTQVLEPTIGNYFRNAAQGSDIIDFLKNRTKRQDEARLAISAALVEYNVGAVDTLIGDIVPPDDLMRTLTDRKIAEQERVTYETQREAQGVRQALEQATALANTQAHVVDAERRVQIAEFEAQAAVKSAEGSAKSKTINAQADATVLRTVGEAEGAKILAVGGSEAKVIQQKVDAMDAGNYAVVQVAEALAKGGIKIVPDIVAGGNSEGGMGGGLVSVLLGNLIRDQNDARKHVAKDEVKPGSAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H428</accession>
    <name>A0A2S9H428_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0735</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94732">
        <property type="protein sequence ID" value="PRC94732"/>
        <property type="gene ID" value="S2091_0735"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="99" mass="10800" checksum="0FF251BBB21411B8" modified="2018-07-18" version="1">MHCMGARANRHAVDHKKAKTDAMQLRKSRQTSEELNMQMTAADIVWIKGQASYEDGDTPEQAGIKALQHGYLPESESYAGFGKGIVQLIEPGAHDGSDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4H7</accession>
    <name>A0A2S9H4H7_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Pseudouridine synthase</fullName>
            <ecNumber evidence="3">5.4.99.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_0085</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the pseudouridine synthase RsuA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.-" evidence="3"/>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94890">
        <property type="protein sequence ID" value="PRC94890"/>
        <property type="gene ID" value="S2091_0085"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140098">
        <property type="term" value="F:catalytic activity, acting on RNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009982">
        <property type="term" value="F:pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034470">
        <property type="term" value="P:ncRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001522">
        <property type="term" value="P:pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1560">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.580">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042092">
        <property type="entry name" value="PsdUridine_s_RsuA/RluB/E/F_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006145">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000748">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluB/E/F"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018496">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020094">
        <property type="entry name" value="TruA/RsuA/RluB/E/F_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00849">
        <property type="entry name" value="PseudoU_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00093">
        <property type="entry name" value="TIGR00093"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01149">
        <property type="entry name" value="PSI_RSU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PseudoU_synth_2" evidence="4">
        <location>
            <begin position="3"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC94890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="182" mass="20704" checksum="39C9E09D3D8ABEEB" modified="2018-07-18" version="1">MKLILFNKPFQVMSQFSAHETRPTLANYITIPGIYPAGRLDADSEGLMLLTDNGQLQHKISHPDHKEAKTYLVQVEGIPDKEQLHRLSQPLNLGDFTTQPCQVQHIQPPEWLWPRTPPIRERIEIPTNWLAITLKEGKNRQVRRMTAAVGLPTLRLVRSAIGPYSLASHPLLPGEWLEVTLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H578</accession>
    <name>A0A2S9H578_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Flavin reductase like domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0286</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95091">
        <property type="protein sequence ID" value="PRC95091"/>
        <property type="gene ID" value="S2091_0286"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016646">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002563">
        <property type="entry name" value="Flavin_Rdtase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01613">
        <property type="entry name" value="Flavin_Reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00903">
        <property type="entry name" value="Flavin_Reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavin_Reduct" evidence="1">
        <location>
            <begin position="19"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC95091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="202" mass="21857" checksum="B92BB75311F307DE" modified="2018-07-18" version="1">MNFDPQKIEPRHCYQLLVGSIIPRPIAWISTLSVDGVLNLAPYSFFTVASCNPPVLLVTQVNPSNQANKDTLTNLKATKECVVNIVSNECVAAMNASCADYPSDVSEFIAVGIDTVASLMVAPAGVKATQVRFECTLREVIEVSAMPAGGTMMLLDVVNIYVNEMILQENQIAPELLDAIGKLGGDYYSTTRDSFKLVRPAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H595</accession>
    <name>A0A2S9H595_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ModE molybdate transport repressor domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_0332</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the ModE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95137">
        <property type="protein sequence ID" value="PRC95137"/>
        <property type="gene ID" value="S2091_0332"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030151">
        <property type="term" value="F:molybdenum ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015689">
        <property type="term" value="P:molybdate ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008995">
        <property type="entry name" value="Mo/tungstate-bd_C_term_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016462">
        <property type="entry name" value="ModE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003725">
        <property type="entry name" value="ModE-bd_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004606">
        <property type="entry name" value="Mop_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005116">
        <property type="entry name" value="Transp-assoc_OB_typ1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03459">
        <property type="entry name" value="TOBE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005763">
        <property type="entry name" value="Txn_reg_ModE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50331">
        <property type="entry name" value="SSF50331"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00637">
        <property type="entry name" value="ModE_repress"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00638">
        <property type="entry name" value="Mop"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51866">
        <property type="entry name" value="MOP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4 5" id="KW-0500">Molybdenum</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Mop" evidence="6">
        <location>
            <begin position="130"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="domain" description="Mop" evidence="6">
        <location>
            <begin position="202"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR005763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC95137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="270" mass="28665" checksum="BCA7D812F2B85F0B" modified="2018-07-18" version="1">METKDNAIKLDSSVWMTVGGENFGDQSRVALLAKIAECGSITQAAKEIKMSYKAAWDAIDKMNTLAGEPLVERVSGGKGGGGTRLTQRGTQLVQNFKIIELEHRRFIDQLSQQSLGIADDLLLIRRMNMKTSARNQFLGKVSAIKHGSVNDEIELQIAGGHKIVAIITHESTEELGLQVGVEAFALMKASSIIVMTDCEGAKFSARNRLSGVVARLISGAVNTDVLIELTGGGSISAIITNESCNTLGLTVGVHATGIFKASSVILGIPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5G5</accession>
    <name>A0A2S9H5G5_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protein-glutamate methylesterase/protein-glutamine glutaminase</fullName>
            <ecNumber evidence="5">3.1.1.61</ecNumber>
            <ecNumber evidence="5">3.5.1.44</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">cheB</name>
        <name evidence="10" type="ORF">S2091_0368</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>H2O + L-glutaminyl-[protein] = L-glutamyl-[protein] + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:16441"/>
            <dbReference type="Rhea" id="RHEA-COMP:10207"/>
            <dbReference type="Rhea" id="RHEA-COMP:10208"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29973"/>
            <dbReference type="ChEBI" id="CHEBI:30011"/>
            <dbReference type="EC" id="3.5.1.44"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>[protein]-L-glutamate 5-O-methyl ester + H2O = H(+) + L-glutamyl-[protein] + methanol</text>
            <dbReference type="Rhea" id="RHEA:23236"/>
            <dbReference type="Rhea" id="RHEA-COMP:10208"/>
            <dbReference type="Rhea" id="RHEA-COMP:10311"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17790"/>
            <dbReference type="ChEBI" id="CHEBI:29973"/>
            <dbReference type="ChEBI" id="CHEBI:82795"/>
            <dbReference type="EC" id="3.1.1.61"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="5">Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.</text>
    </comment>
    <comment type="PTM">
        <text evidence="5">Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the CheB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.61" evidence="5"/>
    <dbReference type="EC" id="3.5.1.44" evidence="5"/>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95173">
        <property type="protein sequence ID" value="PRC95173"/>
        <property type="gene ID" value="S2091_0368"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000156">
        <property type="term" value="F:phosphorelay response regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008984">
        <property type="term" value="F:protein-glutamate methylesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050568">
        <property type="term" value="F:protein-glutamine glutaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018277">
        <property type="term" value="P:protein deamination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006482">
        <property type="term" value="P:protein demethylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd16432">
        <property type="entry name" value="CheB_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00099">
        <property type="entry name" value="CheB_chemtxs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008248">
        <property type="entry name" value="CheB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035909">
        <property type="entry name" value="CheB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000673">
        <property type="entry name" value="Sig_transdc_resp-reg_Me-estase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01339">
        <property type="entry name" value="CheB_methylest"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000876">
        <property type="entry name" value="RR_chemtxs_CheB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52738">
        <property type="entry name" value="SSF52738"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50122">
        <property type="entry name" value="CHEB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5 6" id="KW-0145">Chemotaxis</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 5 7" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="8">
        <location>
            <begin position="5"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="domain" description="CheB-type methylesterase" evidence="9">
        <location>
            <begin position="169"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="active site" evidence="5 6">
        <location>
            <position position="180"/>
        </location>
    </feature>
    <feature type="active site" evidence="5 6">
        <location>
            <position position="207"/>
        </location>
    </feature>
    <feature type="active site" evidence="5 6">
        <location>
            <position position="299"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="5 7">
        <location>
            <position position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC95173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="358" mass="38522" checksum="162D7547E64BBC9D" modified="2018-07-18" version="1">MSRLRVLVVEDSLTVRKRLCEVLSMDPDIILVGEAEDGKQGIELCMALRPDVISLDMMLPVMSGLAATEYIMAYCPTPILIVSSSFNRGEIFKTYEALAAGAVELMEKPTDQDGEGEWERRYIAMLKLVARVKVVTHLRGRKGALQEPAPALAPVPVFIPTLASQPRMPCAMRLVAIGASTGGPSALVNVLRALPADFPLPVLIVIHISEPFETAFAEWLDAQTPHKVRIASEGQLLNKPGVFIAPAEHHLIVRDRRLHITNDPERYSCRPSVDVLFESVALDYGASAVACLLTGMGQDGARGLLALHQAGGITIAQDEASCVVYGMPREAALLGAAQRVLPLSEIGPALATLGRIAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5I2</accession>
    <name>A0A2S9H5I2_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Transport permease protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_0440</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell inner membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the ABC-2 integral membrane protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95245">
        <property type="protein sequence ID" value="PRC95245"/>
        <property type="gene ID" value="S2091_0440"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC_2_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000412">
        <property type="entry name" value="ABC_2_transport"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51012">
        <property type="entry name" value="ABC_TM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="160"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="205"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="242"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="276"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="327"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="domain" description="ABC2_membrane" evidence="7">
        <location>
            <begin position="114"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC95245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="355" mass="38574" checksum="A65D25C34B859A11" modified="2018-07-18" version="1">MYSRIFFNQLLMGLKIYLRVPSAMFWMIAFPIVMLMGMGTIFGGSSNSGIKLVWSQTAADSSEDVSLRHALAELGLTLEMLTPTQAEERWKEGKLPALLERQGERYSMRVNSYLSGQGMPVVSLVQQGFLMVQARALGTVELTRIPVVMSSPGGHHDGPYAAYLLPGLLGLNLLMMGVFSTGMVDVTLREKGGYKRLATTPLPRHIYLAAQLGVRLTVVIAAAAMLMLVGALVFGITNQGSYLSLLVLLVLGSACFTSMGYLLASFARNVDVYSGFSNMVFLPLMLLSGVYFSLDSAPVWLQRGADILPLTPLLKALRAVFNDGASLTSLGSSLAILAGWTLLLFVLASKRFRWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5P1</accession>
    <name>A0A2S9H5P1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0391</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95196">
        <property type="protein sequence ID" value="PRC95196"/>
        <property type="gene ID" value="S2091_0391"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007922">
        <property type="entry name" value="DUF721/UPF0232"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05258">
        <property type="entry name" value="DciA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC95196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="172" mass="18836" checksum="BEFEB8FA75ED7345" modified="2018-07-18" version="1">MATPMKTNRPSTAPFRAGSARPANKGKPSQSVEVNSLLRNQLAHLWPTISNNAALQKECATALPQLFLYCQVLQLEAEQLVLAAPNAALASKLKQQLPKLQTALQKAGWQINAIRIKVQVTLALHNEPAEKQCLFSDSALKAFDSLEKNLAGSKHNDELLGALRTLLNRHKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5S8</accession>
    <name>A0A2S9H5S8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0431</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95236">
        <property type="protein sequence ID" value="PRC95236"/>
        <property type="gene ID" value="S2091_0431"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012434">
        <property type="entry name" value="DUF1631"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07793">
        <property type="entry name" value="DUF1631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="266"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="266"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC95236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="764" mass="85133" checksum="266E7184646D6328" modified="2018-07-18" version="1">MITEHQPPKKGMSHSSRIVILQSLVPIATSLTATQLEGFSLRLGEALFRLSDQSVRPEEANISFHSYNHLKKNSSAFYRLASSKLSELFAHEVRILEKGHKPRQLEDDSSLALVTFDEMENKVLLETLSQSIELDNADELVKLNLRISHLLKIEQINVRYNPFRPEVFLKAIYKAWCEFEPVSDSHHMILRILRPEMFLQLNPVLRELNNALIERGILPKATDLLRVNKHQSLANSTSSTLSKKLAVDPFFESKIKGILYANQGDAAQGEQGQGSGQHQASGQGYGSGQGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGFPDDARNPLDETQNIALGKQGTVTIGRELFEYLTSVQATGAALGPAAQNAPTLRGIVEQAPENTITQIDNNTIGLLAKIFDYVFSDPHIPTDLKNLIGQLQIPTLKAALIDREFFFKQTHPARVLIDTLAKSSVTWNPDKGVDDPLYKMIARTVERVQKEFDQQLELFSDVAADLTQFIEEEERLSEKAIEEPIAQAIQQEKIRQARELATNDVATRTDTGEVAGFIEAFLEQQWVNILVLAHTVKEQKPQALERTLKTMDDLIWSVKTKNSVEERHELVNKLPALLSSLNTWLNAIKWEDPSRVIFFSKLAERHASIARAPLEVSTRRQVEMAVNVAQKASERSLKKNKHEHTMPDQFVFFIDQIERGSWFDFTRNNGSVVRFKLAWVSPRRSRFIFTNRQGHDAFSISSEELLDIFRSGKAQMISDEPVVDRALQSVIDDRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSK3</accession>
    <name>A0A2S9GSK3_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Protease HtpX homolog</fullName>
            <ecNumber evidence="12">3.4.24.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">htpX</name>
        <name evidence="14" type="ORF">S2091_4586</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="12">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Cell membrane</location>
            <topology evidence="12">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the peptidase M48B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="12"/>
    <dbReference type="EMBL" id="PUGF01000038">
        <property type="protein sequence ID" value="PRC90693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90693">
        <property type="protein sequence ID" value="PRC90693"/>
        <property type="gene ID" value="S2091_4586"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00188">
        <property type="entry name" value="Pept_M48_protease_HtpX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022919">
        <property type="entry name" value="Pept_M48_protease_HtpX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001915">
        <property type="entry name" value="Peptidase_M48"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01435">
        <property type="entry name" value="Peptidase_M48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 12" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 12" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="4 12 14" id="KW-0645">Protease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="8 12" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="5"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="38"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="158"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="194"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M48" evidence="13">
        <location>
            <begin position="80"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="active site" evidence="12">
        <location>
            <position position="145"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="144"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="148"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="223"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="PRC90693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="291" mass="31021" checksum="F12A1281B4061695" modified="2018-07-18" version="1">MKRIFLFLATNLAVMLVMSVVLSLLGVNRYLTANGLNFSMLMVFSLVVGFTGAFFSLLISKPMAKWSTGARVIDAPTTSTELWLVSVVKNLAERAGIGMPDVAVYDGAPNAFATGAFKNSALVAVSTGLLESMTREEVEAVLGHEVAHIANGDMVTMALIQGVVNTFVVFLARVVGYVIDKAIFKNSDDDRPGIGYMVTVFVCEIIFGFAASIIVCWFSRQREFRADAGSAKLMGNGQPMINALSRLGGLVPGELPKSMAASGISDKAGVAALFSTHPPMEERIAALRALN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSN6</accession>
    <name>A0A2S9GSN6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4547</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000037">
        <property type="protein sequence ID" value="PRC90721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90721">
        <property type="protein sequence ID" value="PRC90721"/>
        <property type="gene ID" value="S2091_4547"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC90721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="78" mass="8452" checksum="A67C5B013535C7E7" modified="2018-07-18" version="1">MVQLNKIMGHVGLVMAFVSLPLMLAGVISTDAYSLAAQTQARGDFALMQSADNTSRVEHGDNTALQFTESHERQVTTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSZ5</accession>
    <name>A0A2S9GSZ5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4418</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000034">
        <property type="protein sequence ID" value="PRC90837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90837">
        <property type="protein sequence ID" value="PRC90837"/>
        <property type="gene ID" value="S2091_4418"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="37" mass="3856" checksum="E5B95AC194E51FEE" modified="2018-07-18" version="1">MSNLLEISQPTSSEASLTPAQQSQILADDNAAVEQPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GT38</accession>
    <name>A0A2S9GT38_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glutathione-dependent formaldehyde-activating enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_4373</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Gfa family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000033">
        <property type="protein sequence ID" value="PRC90880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90880">
        <property type="protein sequence ID" value="PRC90880"/>
        <property type="gene ID" value="S2091_4373"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016846">
        <property type="term" value="F:carbon-sulfur lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006913">
        <property type="entry name" value="CENP-V/GFA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011057">
        <property type="entry name" value="Mss4-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51316">
        <property type="entry name" value="SSF51316"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51891">
        <property type="entry name" value="CENP_V_GFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CENP-V/GFA" evidence="3">
        <location>
            <begin position="11"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC90880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="129" mass="14514" checksum="ACFE6DC2DF06392C" modified="2018-07-18" version="1">MTEETSNLPILQGSCHCGAVRLTLPSMPEVATKCNCSLCRRLGGLWSYYPFGTVRIEGHPENTTDYVWGDKTLRIIRCKICGCATHWEPIDRELGARHGVNLNNFDPGLQESVRVRHFDGADSWTFIDC</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GT63</accession>
    <name>A0A2S9GT63_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4379</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000033">
        <property type="protein sequence ID" value="PRC90886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90886">
        <property type="protein sequence ID" value="PRC90886"/>
        <property type="gene ID" value="S2091_4379"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC90886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="87" mass="10229" checksum="07DDCEDEB570FD1C" modified="2018-07-18" version="1">MKFKDAIVYKNERFSVGVEEEAGKYYLSIPVSNNLVDYEEYYDINKEEFDRFSSSVEDAAEFVQQCRSRQRDDRLMVRPGNDRGTAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTE5</accession>
    <name>A0A2S9GTE5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Nucleotidyltransferase domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_4283</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000031">
        <property type="protein sequence ID" value="PRC90987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90987">
        <property type="protein sequence ID" value="PRC90987"/>
        <property type="gene ID" value="S2091_4283"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002934">
        <property type="entry name" value="Polymerase_NTP_transf_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01909">
        <property type="entry name" value="NTP_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NTP_transf_2" evidence="3">
        <location>
            <begin position="23"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC90987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="117" mass="13034" checksum="2B1F76A4E50E04C0" modified="2018-07-18" version="1">MQTQAMHPLDMATAATVKAFMERVTAVFSVRSAILFGSRARGEFKPDSDADVAVLLSGQHGKFMDAKMAMSDIAFDVMLDTGIRVEAIPLWEDEWANPDAYRNPFLLRNIERDGIIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTG4</accession>
    <name>A0A2S9GTG4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4287</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000031">
        <property type="protein sequence ID" value="PRC90991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90991">
        <property type="protein sequence ID" value="PRC90991"/>
        <property type="gene ID" value="S2091_4287"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC90991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="69" mass="8018" checksum="65846AF5F801CED4" modified="2018-07-18" version="1">MPTQEITFSDDERDMLERVRLQQGLATLEQTAEWLVKSRLRNQTKHFTGRGRSLYAVTASSTRKSHESH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTH6</accession>
    <name>A0A2S9GTH6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Bacteriophage replication A protein (GPA)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_4292</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Possible endonuclease which induces a single-strand cut and initiates DNA replication.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the phage GPA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000031">
        <property type="protein sequence ID" value="PRC90996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90996">
        <property type="protein sequence ID" value="PRC90996"/>
        <property type="gene ID" value="S2091_4292"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008766">
        <property type="entry name" value="Replication_gene_A"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05840">
        <property type="entry name" value="Phage_GPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0235">DNA replication</keyword>
    <keyword evidence="5" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0540">Nuclease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="565"/>
            <end position="611"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009260"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC90996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="624" mass="71230" checksum="6D7908B170CD9F99" modified="2018-07-18" version="1">MAFACMKELVMRSKQREMPAQRRHELFFETAKFKTEIAHIPYKWRKRLIARTLDKMAWSSWHKIYESIAVNFVRDFAKQYVPAGINMTQDDNDIIATAKKAAGQVSQGLCAAQSDQHALLIISALCRDYGIDTPAFEELADVVARAIDHRWWRRQLRKSIGRAFEAGNIRLGYVHYRGEPYASNEAVLGRLAQNRRNALAMAATVLENENGEQFSIADLAEKTTANKSIRRGELMLRINGFETIARETGDQGIFVTWTCPSHFHATRRNGYANPKYSHATPREANQYLCKMTALCRSALARLGIGIYGFRIAEPHHDSCPHWHMLLFVRPTEKYKKHHIHDVAGRAIRIMKRYAWRTERGEPGAFEHRLDVKRIDWSKGSAAGYIAKYVAKNIDGVEQHKTREGYTVATDLNGDVELTPSMRVETWAAKWGIRQFQQWGGAPVTIWRELRRIKKEMVNKAPEPMRRAWDAVQKIDGEKRADWAEYLRAQGGAIVPRKELVITLAKDEKTVIGRYGETIKVTPYGVHCSALIGVVFKSVRHTWMPVNNGGDGAVFDLPRTRVNNCTHQNPESPKTRLNSSTFDVNDQSENNKRTTNGDIRGTNFPISKNDQLKTQPRIKELTNEC</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTS4</accession>
    <name>A0A2S9GTS4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4207</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000029">
        <property type="protein sequence ID" value="PRC91111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91111">
        <property type="protein sequence ID" value="PRC91111"/>
        <property type="gene ID" value="S2091_4207"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRibTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00156">
        <property type="entry name" value="Pribosyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pribosyltran" evidence="1">
        <location>
            <begin position="15"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="192" mass="21308" checksum="C6CEE75BDFF05808" modified="2018-07-18" version="1">MKPIQQFDAEALYLELARQIKAAVANLNNVAIVGIYSGGAWLAERLAHDCQIKNPVGYIDVSFYRDDYAQKGLHAEVKTTQIPFEVDGANIILVDDVLFTGRTTRAAINELFDYGRPNQILLACLVDRGGRQLPYAADFVAQQLTLPLNLSLQLQRELVADQTAEQASKLILSLVEISDHKNDDIEPTPTKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTT9</accession>
    <name>A0A2S9GTT9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Efflux transporter, RND family, MFP subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_4214</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000029">
        <property type="protein sequence ID" value="PRC91118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91118">
        <property type="protein sequence ID" value="PRC91118"/>
        <property type="gene ID" value="S2091_4214"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006143">
        <property type="entry name" value="RND_pump_MFP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01730">
        <property type="entry name" value="RND_mfp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="40"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="domain" description="HlyD_D23" evidence="4">
        <location>
            <begin position="105"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="178"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC91118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="416" mass="44434" checksum="229A308F347177F6" modified="2018-07-18" version="1">MSEKRHANLGIHTDAATGSHSATHAHHVAHAPILKRAKMISILIVLLLLLGAGVTVVLRVLHSQTLASATEQDARVFVSVIHAQGGGKTETITLPSTLQGIIEAPIYARSSGYVLRWKKDIGSSVVKDEVLAEIDTPEVDSQLAQAIAARAQSASSLDLAKTSAERWEELRKKDAVTQQELNERRSAYTQAVANVEAADANVQRLQKLEGFKKVLAPFSGVITRRNVEVGDLIDAGNGGAGRALFTMAQVDPLRLYVYVPQAFAQRINIGDSVSVTQNEMRDQVFQGKVVRAAGAIDAATRTLQMEINLPNHDNKLLAGSYVQVALSANGTSNVLRVPSNVLLFRPEGTRIAVVDNAGHVQLHTVTVGHDLGNSLEILSGITAADNLIVNPADSLADNDIVTVQKDKPEAAGKAHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTW9</accession>
    <name>A0A2S9GTW9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Efflux transporter, RND family, MFP subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_4067</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000027">
        <property type="protein sequence ID" value="PRC91172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91172">
        <property type="protein sequence ID" value="PRC91172"/>
        <property type="gene ID" value="S2091_4067"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006143">
        <property type="entry name" value="RND_pump_MFP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01730">
        <property type="entry name" value="RND_mfp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HlyD_D23" evidence="2">
        <location>
            <begin position="54"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="373" mass="39982" checksum="48895B1AE9F24144" modified="2018-07-18" version="1">MTKRLLIMLGCIVVLIAGIAFGFYLHIQKLIASSPKPSAQTVTTTKVAAAEWQPQLSSVGTVTAYRGVDVTSEIAGLVREIKFKSGQHVKKGDLLIALNADSDIAQLQALEASAELAATVLKRDEAQLAVEGVSQAQVDADKADLKNKRALVAQQTALVEKKTIRAPFAGRLGITAINPGQYVNPGDKLVTLQTIDPIYVNFSIPQKQSSMLKVDQNLKIISDAYPEAPFAGKVNAINPVVDASSRNVQVQAKLSNEKQQLLPGMFANVSLDVGDKNKYITLPQTAITYNPYGSTVFVVKQGKDDKGAAMLKVNQVFVTTGATRGDQVAITKGLEVGQEVVTSGQLKLKNDTWIVVDNSVLPANDPNPTPQEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GU37</accession>
    <name>A0A2S9GU37_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Histidine kinase</fullName>
            <ecNumber evidence="3">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">S2091_4118</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="3"/>
    <dbReference type="EMBL" id="PUGF01000027">
        <property type="protein sequence ID" value="PRC91223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91223">
        <property type="protein sequence ID" value="PRC91223"/>
        <property type="gene ID" value="S2091_4118"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033479">
        <property type="entry name" value="dCache_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02743">
        <property type="entry name" value="dCache_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="309"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="14">
        <location>
            <begin position="330"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="13">
        <location>
            <begin position="467"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="12">
        <location>
            <begin position="569"/>
            <end position="802"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="PRC91223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="814" mass="91976" checksum="F367340C149B6C6D" modified="2018-07-18" version="1">MKLKLNIIYKLIGYLVIVSALPLLIFAIISYDVVRDTILDLTGQYSTQLVGNQRDYLQQQVVEQIENLATRIASSEEISAVLVKADSTNNREHNTFDELSTQAEIRQSLSLYSSLKGIVSIDLFSVRGHQFYVGDTLSEPLVDDKVRVALFIAAIAEKKPVYWRGVENNLNTASTAHKVLTAIKVIRHFSATSQLSEPVGMLLINYSTDYLFDHFSQVDLGLHSYMIVTDSEGRMIYSPERGKIGQVMSDEIKSQLKNQMELNSGSSIIHINGRDNLVSMAKLDTKTWRVFGIIPQETLLAPMNRLTQILMMLVILSFIVIFFASQIFRRNMVAPIQAISDGFRRIQDKNINLAHHLVVPKSKDEISELVVWFNEFLDTHRMRLQYEQDLLDSQYKFASIFKQAPMPLALVRIETGEFIDVNDFWLDQFGYSRNEIIGRTSMEMKLWLDISDRNLALDQIKQTKVVNRFEIRQRTKDGRILICLMSGRPIKFQDDTFFIFAPVDITGQRAAELEIQENNLQLESRVLSRTAQLQKTNEELNLALESLNLTKGELVRSEKLAALGSLVAGVAHEINTPVGIIVTSASVLNDASTEINNNVNEGNIRKSQIVEYIHVAIESSRLIIANANRAARLIQSFKQVAVDQTSEQRREFELHEFLHELITSLNPTLRKAKTKIEMRPGGISQIRMDSYPGLLAQVVTNLTMNSVTHAFNNRDFGHIIIETNLADDHVLINFRDDGCGIPEDILGKIFDPFFTTRRGQGGTGLGLNIVFNIVSKQFSGTISAHNNADGGALFKINIPRITRQLSDNEYIRIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GU38</accession>
    <name>A0A2S9GU38_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cyanophycin synthetase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_4032</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000026">
        <property type="protein sequence ID" value="PRC91247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91247">
        <property type="protein sequence ID" value="PRC91247"/>
        <property type="gene ID" value="S2091_4032"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009059">
        <property type="term" value="P:macromolecule biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005479">
        <property type="entry name" value="CbamoylP_synth_lsu-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011810">
        <property type="entry name" value="Cya_phycin_syn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044019">
        <property type="entry name" value="Cyanophycin_syn_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036565">
        <property type="entry name" value="Mur-like_cat_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02786">
        <property type="entry name" value="CPSase_L_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18921">
        <property type="entry name" value="Cyanophycin_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53623">
        <property type="entry name" value="SSF53623"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02068">
        <property type="entry name" value="cya_phycin_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-grasp" evidence="2">
        <location>
            <begin position="225"/>
            <end position="478"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="728" mass="78477" checksum="39085BF1976A026A" modified="2018-07-18" version="1">MTNKKDIKFTRVTYLRGPNIWTYRPVIEAWVDIGDLENHPSNTLPGFNDRLIAWLPSLIEHRCGVGERGGFIERLHTGTWAAHVLEHIVLELQNLAGMRTGFGKTRKAAEPSLYKMAFRTRQEQVGRAALVAGRELLLAAIENTAYDVTAKVAELSSLVDSLCLGPSTAHIVDAATTRSIPWLRLNDGNLVQLGFGNKQRRIWTAETDQTSAIAESISSDKDLTKSLLKSCGVPVPEGSLVHSAEEAWEAAQDIGLPVVVKPYDGNHGRGVSLDLKNEADVIAAFKLADRKGDGSAVIVEQFIPGNEHRVLVVGKKVVAVAAGEAAWVTGDGKSNIIELVDSQINSDPRRGTTEEFPLNALGPQNGAEIILELERQGFTAYDIPTEGHRVLIQRNGNVAFDVTDQIHPSIAAIATLAARVVGLDVAGVDLVVEDISKPLNSQRGAVIEVNAGPGLLAHLKPASGLPRPIGTAIIDHLFPNDGSGRIPIIGVTEASGSTLIARLIAHLIHVSGKHVGLACSTGLYLDHRQIDSKNGINWDAGQRLLINRSIDAAVFETSHRMILSEGLVYDKCAVGVVSEITENLNTADLSEFYITDHDKLFNIVRTQIDVILPSGVAVLNAANPRIVEMAELCDGTVIFYGDNPTLAAIIKHRAEGERVVFLRDNTIVLANGEQETALLPLSSLKPTKAAQPANVMAAVAAAWALNISPELIEAGLRTFESNPKKTHY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUD6</accession>
    <name>A0A2S9GUD6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Methyl-accepting chemotaxis protein (MCP) signaling domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_3989</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyl-accepting chemotaxis (MCP) protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000025">
        <property type="protein sequence ID" value="PRC91318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91318">
        <property type="protein sequence ID" value="PRC91318"/>
        <property type="gene ID" value="S2091_3989"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004089">
        <property type="entry name" value="MCPsignal_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00015">
        <property type="entry name" value="MCPsignal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00283">
        <property type="entry name" value="MA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50111">
        <property type="entry name" value="CHEMOTAXIS_TRANSDUC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0807">Transducer</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="293"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="5">
        <location>
            <begin position="317"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="domain" description="Methyl-accepting transducer" evidence="4">
        <location>
            <begin position="376"/>
            <end position="605"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00029447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC91318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="642" mass="68290" checksum="B901D5BFAF53EF98" modified="2018-07-18" version="1">MNIWQRLSIQKKLLLSMAFCLLLFLIISSALSIIMTGEGIRERVTTQELPAVVGEIRNDILRQIGEPMAISSSIANNTYLLDWEVAGLGDDGLAGWKRYATKLKEQSHAATVFWISEGTGKYFTEAGLNRTLDKSSDVNQWFYSFLASGKPYTLNIDKDVASGSYMLFVDTRFDAQGKHGVSGLGLSVDTLANTIRSYHVGKSGFVYLVRANGSMLIHRDPALVDGNHFLKDLPGFNQELSSKLLSGEKFTSSIYSSQAGKQIVASSFVPELNLYVIAEVPESEVLGNVMKTAFISAMVAGLVGGSIGLFMIFMVSRAIAAPVARAAGMLGEIADGDGDLSRSMRVESEDEIGALANAFNRFVASLNKTISAVRVSTETIALASSEISAGNLDLSNRTEAQASSLEETASAMEQLTSTVKQNADNARQANQLVVSASGVAIKGGEVVGQVIQTMGSIKDSSRKIVDIIGVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVASEVRNLAQRSAAAAKEIKSLIDDSVGKVDVGSKLVDEAGATMNQIVTSVKQVVAIMAEIAAASQEQSAGIEQVNLAITDMDNTTQQNAALVEQAAAASKSLQDQADSLAKIVSVFKLDESSLEVVRDVRHGSPPRLSER</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUF1</accession>
    <name>A0A2S9GUF1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4011</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000025">
        <property type="protein sequence ID" value="PRC91340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91340">
        <property type="protein sequence ID" value="PRC91340"/>
        <property type="gene ID" value="S2091_4011"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010281">
        <property type="entry name" value="DUF885"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33361">
        <property type="entry name" value="PTHR33361"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05960">
        <property type="entry name" value="DUF885"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="620" mass="67412" checksum="C7392D61962ED0C9" modified="2018-07-18" version="1">MTDTSFHYSRREVLKMTLTAAAVSAMPRLVLAQTATASDAQFSTMLGDFAEEILRLAPTSATTLGLDSGTRIALKSQLGDASPEGDAQWTDQVKSMLSRMSTVNRATLSPETQIVYDKVQYAASEGVAGTRFSYGDAASGFFGGASPYPVTQQDGALWRTPEFLDSQHQILNRDDAESYLARVAALATVLDQETARITEQASKGIMPPDFIARTTLGQLSGYRKTPTASQKLVTSITERTKKLGIDGDWEVRATQLVNAKIYPALDRQITAFAKATAKAKNIAGVYHLPDGAAYYAWALKLGTSTTSSPREIHAIGLEQNKMLQARIDTILKAQGISHGTVGARMLALSKDPSRFYADNDQGRDQIIAFCNDRVAAARALMPKISHLNMKAPLVVKRVPQDIEAGAPLGYMNFASLDGSRPAIYYINLKSTTLWPRDQLSTLTAHEGIPGHAWQGAYLAEHHAELPLISSLIGFNAFVEGWALYAEQLVDEFGLYANDPFSQIGYLQAQQFRACRLVVDTGIHEMKWTAKQAIQFMVENTGRGVGAMTSEVHRYAVSPGQACGYKMGHNEILRQRERAKAELGAKFDLAAFNDALVTSAGVPLTVLPTVIDRYIAGAKTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUH8</accession>
    <name>A0A2S9GUH8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3915</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000024">
        <property type="protein sequence ID" value="PRC91370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91370">
        <property type="protein sequence ID" value="PRC91370"/>
        <property type="gene ID" value="S2091_3915"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="52" mass="5718" checksum="E98C37FACCA7E4C2" modified="2018-07-18" version="1">MLVSVEVAFEVAFEVAFEVAFEVAFEVAFEVAFEVAVAVDFDLPPLLVRPVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUT1</accession>
    <name>A0A2S9GUT1_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Inositol-1-monophosphatase</fullName>
            <ecNumber evidence="6">3.1.3.25</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_3884</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>a myo-inositol phosphate + H2O = myo-inositol + phosphate</text>
            <dbReference type="Rhea" id="RHEA:24056"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:17268"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:84139"/>
            <dbReference type="EC" id="3.1.3.25"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 6">Belongs to the inositol monophosphatase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.25" evidence="6"/>
    <dbReference type="EMBL" id="PUGF01000023">
        <property type="protein sequence ID" value="PRC91469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91469">
        <property type="protein sequence ID" value="PRC91469"/>
        <property type="gene ID" value="S2091_3884"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008934">
        <property type="term" value="F:inositol monophosphate 1-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052832">
        <property type="term" value="F:inositol monophosphate 3-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052833">
        <property type="term" value="F:inositol monophosphate 4-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046855">
        <property type="term" value="P:inositol phosphate dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046854">
        <property type="term" value="P:phosphatidylinositol phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01639">
        <property type="entry name" value="IMPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033942">
        <property type="entry name" value="IMPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020583">
        <property type="entry name" value="Inositol_monoP_metal-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000760">
        <property type="entry name" value="Inositol_monophosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020550">
        <property type="entry name" value="Inositol_monophosphatase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022337">
        <property type="entry name" value="Inositol_monophosphatase_SuhB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00459">
        <property type="entry name" value="Inositol_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00377">
        <property type="entry name" value="IMPHPHTASES"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01959">
        <property type="entry name" value="SBIMPHPHTASE"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00629">
        <property type="entry name" value="IMP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00630">
        <property type="entry name" value="IMP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU364068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC91469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="263" mass="28477" checksum="8D73CBF64146F6C9" modified="2018-07-18" version="1">MHPMLNTAIKAARRGATIINRASFDLDRVDATEKQHNDFVSDVDKAAEAAIIEVLISAYPSHAVLAEESGASSNLTKTSEYVWIIDPLDGTTNFLHGFPQYCVSIALQHNGVMTQAVIFDPTRNELFAATKGGGAYLNDKRIRVTKRDKLADSLIGTGFPFRSVTEIENYIPMFKAMSGKCQGLRRPGSAALDLAYVAMGRLDGFFEKGLKPWDIAAGSLIVTEAGGITGTFAGESDYLHKGDIISATPKVFAQMVNILKPFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUY3</accession>
    <name>A0A2S9GUY3_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Bifunctional adenosylcobalamin biosynthesis protein</fullName>
            <ecNumber evidence="12">2.7.1.156</ecNumber>
            <ecNumber evidence="12">2.7.7.62</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">S2091_3807</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4 12">Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>adenosylcob(III)inamide + ATP = adenosylcob(III)inamide phosphate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15769"/>
            <dbReference type="ChEBI" id="CHEBI:2480"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58502"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.156"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>adenosylcob(III)inamide + GTP = adenosylcob(III)inamide phosphate + GDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15765"/>
            <dbReference type="ChEBI" id="CHEBI:2480"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="ChEBI" id="CHEBI:58502"/>
            <dbReference type="EC" id="2.7.1.156"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 12">
            <text>adenosylcob(III)inamide phosphate + GTP + H(+) = adenosylcob(III)inamide-GDP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:22712"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:58502"/>
            <dbReference type="ChEBI" id="CHEBI:60487"/>
            <dbReference type="EC" id="2.7.7.62"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="6 12">Cofactor biosynthesis; adenosylcobalamin biosynthesis; adenosylcobalamin from cob(II)yrinate a,c-diamide: step 5/7.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5 12">Cofactor biosynthesis; adenosylcobalamin biosynthesis; adenosylcobalamin from cob(II)yrinate a,c-diamide: step 6/7.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7 12">Belongs to the CobU/CobP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.156" evidence="12"/>
    <dbReference type="EC" id="2.7.7.62" evidence="12"/>
    <dbReference type="EMBL" id="PUGF01000022">
        <property type="protein sequence ID" value="PRC91529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91529">
        <property type="protein sequence ID" value="PRC91529"/>
        <property type="gene ID" value="S2091_3807"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00148">
        <property type="reaction ID" value="UER00236"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036429">
        <property type="term" value="F:adenosylcobinamide kinase (ATP-specific) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036428">
        <property type="term" value="F:adenosylcobinamide kinase (GTP-specific) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008820">
        <property type="term" value="F:cobinamide phosphate guanylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009236">
        <property type="term" value="P:cobalamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00544">
        <property type="entry name" value="CobU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003203">
        <property type="entry name" value="Cobinamide_kinase/P_G-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34848">
        <property type="entry name" value="PTHR34848"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02283">
        <property type="entry name" value="CobU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006135">
        <property type="entry name" value="CobU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12" id="KW-0169">Cobalamin biosynthesis</keyword>
    <keyword evidence="12 14" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="10 12 15" id="KW-0418">Kinase</keyword>
    <keyword evidence="9 12 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 12 15" id="KW-0808">Transferase</keyword>
    <feature type="active site" description="GMP-histidine intermediate" evidence="13">
        <location>
            <position position="49"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <begin position="8"/>
            <end position="15"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <begin position="33"/>
            <end position="35"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="61"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="83"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000711"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001522"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00003889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00005159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00007490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRNR" id="PIRNR006135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR006135-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR006135-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="PRC91529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="185" mass="20216" checksum="F29815C1BEFBBFA3" modified="2018-07-18" version="1">MTRTLVLGGARSGKSAFAETLAENQGKEVIYIATAQAKDTEMAARIKHHQQQRPASWRLVEEPLALGEALLKWCAPDRVVLIDCLTLWLANLLFDEKTEYPEIGLIPLPELFHEQREQFLTALTQVTGELILVSNEVGLGVVPYGAVSRCFVDEAGRLNQAVAKHCENVLLVAAGLPLVLKGSAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUY6</accession>
    <name>A0A2S9GUY6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="10">TonB-dependent Receptor Plug Domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">S2091_3799</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000022">
        <property type="protein sequence ID" value="PRC91521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91521">
        <property type="protein sequence ID" value="PRC91521"/>
        <property type="gene ID" value="S2091_3799"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039426">
        <property type="entry name" value="BtuB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30069">
        <property type="entry name" value="PTHR30069"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="3 6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 10" id="KW-0675">Receptor</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0798">TonB box</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="domain" description="Plug" evidence="9">
        <location>
            <begin position="101"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="8">
        <location>
            <begin position="256"/>
            <end position="701"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC91521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="702" mass="76325" checksum="C08E35B6D494E1C2" modified="2018-07-18" version="1">MVSSSHVLFNPAYGTLAGCPFTWFFMISSQFLRSTATASARPFLKPQAMSLAIISALASLTCASAFAQTSQTTSGTDNTGSDVAPVVIIGSRFPSSPDLAPIGATVITATDIRNAGVDNVNEAIRKLGGVYGRQNLYGTADFDLDMNGFGADSANNLVILLDGVRISESEQSVALLSSIPIDSVARIEIMRGGSSVLYGDGATGGVIQIITKQLGPTPLTGSITTELGQFKDRAGRAYLSQGGDGFNLSLNVNDQKSDNYRVNNAVTQQNLGGAATWYSDAGRIGLRIDIARQDSGFAGSLTLAQFQQDPRQTFTPYDNGSIATDRYTAFGEYNFGAWQVAAELSTRERTSDVTFFNGTVPSPSSFTGRQTEFTPRLRNITGVDGMRNEFVIGLDFMDWNRQSEGSYSQDYATQKSRAIYFRDEMKIDQARIAFGARREVFDKTSTDPVAFSQDNYTVVQGVNAWEVQGSYAFAPVVNVFANVGQSYRVANVDDNSETTVPNTPLLPQLSHDLELGTTLGDANQQLIARFFRHDITNEIYYFTNVSFPYGTNMNLDPTKRQGIALDAKYRLSKEFRLTAQAQHVDAVFTAGVNDGKELVLVPKNTVSAHLNWVPGNGQNAYIGGQWVDKQRYGGDFSNTCAAMIPSHATLDARYSQTVGAWELAVAGSNLTNKQYFSNSFSCMGSIYPDDGRQMKVTLRYSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVX1</accession>
    <name>A0A2S9GVX1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Parallel beta-helix repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_3420</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000018">
        <property type="protein sequence ID" value="PRC91864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91864">
        <property type="protein sequence ID" value="PRC91864"/>
        <property type="gene ID" value="S2091_3420"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022442">
        <property type="entry name" value="B-helix_rpt-cont_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039448">
        <property type="entry name" value="Beta_helix"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006626">
        <property type="entry name" value="PbH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13229">
        <property type="entry name" value="Beta_helix"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00710">
        <property type="entry name" value="PbH1"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="SSF51126"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03805">
        <property type="entry name" value="beta_helix_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0349">Heme</keyword>
    <keyword evidence="3 4" id="KW-0408">Iron</keyword>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cytochrome c" evidence="5">
        <location>
            <begin position="422"/>
            <end position="503"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC91864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="504" mass="53673" checksum="605DACDD1C4FED10" modified="2018-07-18" version="1">MSKKRIFAGVLALIIAAGAGYFVARKQFLGAISIDTASAQSLLTGARTAGAGKENAAALTSAMSGKIITVKSGELIQDAVNLAKPGDTVQVMPGTYSETVYIDKDNIALIGVIQEGQWPTLDGIGKLNDAVLYSGNGIRVENFKIIKYKGNAIMGQAGNNFVIRHNWIQDTGVYGIFPQFGQNGLIQYNVLSGIEDAAIYVGMSDNIQVDHNEVHGNVAGIEIENSRHAVVENNMVYDNAGGILTFVTPWLPIKTTFDVIIRNNFIVDNNHKNFGAPGSIVSGVPSGSGIIVMAAKDVMIENNVIRNNKNAGIIVADHKSFANITIDPESDPYPDRIQVLSNLFSNNGTEPMDEIKALMLASMTRQGPDIVAVGGGSGSCMVDRATHATLGISSWAANCPKATTADIVTLLLDKPAVPRSTATVTKGQVLYNGICAGCHAYSARMIGPPTQIIQALYLGNPQGIADYIAKPSKKREDFPPMPSQGHLTPELRLTVAEYMLSVKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVX3</accession>
    <name>A0A2S9GVX3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Flagellar motor protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_3404</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MotB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000018">
        <property type="protein sequence ID" value="PRC91848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91848">
        <property type="protein sequence ID" value="PRC91848"/>
        <property type="gene ID" value="S2091_3404"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07185">
        <property type="entry name" value="OmpA_C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025713">
        <property type="entry name" value="MotB_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006665">
        <property type="entry name" value="OmpA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036737">
        <property type="entry name" value="OmpA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13677">
        <property type="entry name" value="MotB_plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00691">
        <property type="entry name" value="OmpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103088">
        <property type="entry name" value="SSF103088"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51123">
        <property type="entry name" value="OMPA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0966">Cell projection</keyword>
    <keyword evidence="8" id="KW-0969">Cilium</keyword>
    <keyword evidence="8" id="KW-0282">Flagellum</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="domain" description="OmpA-like" evidence="7">
        <location>
            <begin position="139"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="74"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC91848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="281" mass="30251" checksum="F94246FB429F9EEA" modified="2018-07-18" version="1">MRKRRPIEDEVNHERWLVSYADFITLLFAFFVVMYSLSSLNEGKYRVMSDSVITAFGQFRTFSDNTMPTAPKLNPGPGPGPGVGIGNGPGPGLSSVKKKSAVEEPLRQEREKMTGLAQGILSALAPLIREGKVRVTQTSRGVSIDINASVLFASAEAKLTRESSQALLAIASVLASDAHAIQVEGYTDNQPIKNGIFPSNWELSAVRAGSVVRLFMDNGIAEDRLTAIGQGAKMPVATNDTAEGRSRNRRVNITILALLPDKQTEVPINDNNADKGAISGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVY3</accession>
    <name>A0A2S9GVY3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">TPR repeat</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_3443</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000018">
        <property type="protein sequence ID" value="PRC91887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91887">
        <property type="protein sequence ID" value="PRC91887"/>
        <property type="gene ID" value="S2091_3443"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027843">
        <property type="entry name" value="DUF4440"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14534">
        <property type="entry name" value="DUF4440"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015672954" evidence="3">
        <location>
            <begin position="27"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="93"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4440" evidence="4">
        <location>
            <begin position="278"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="246"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF14534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC91887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="385" mass="41801" checksum="508EE98244569C1C" modified="2018-07-18" version="1">MTSKHTRSWFIALSLAIAALTSSAWADDSADVNKLIQNKQLPEAMQKADAYLVQHPKDAQMRFLKGLIFAEQNKTNEAIAVFTKLTEDYPDLPEPYNNLAVLFASSNQFDKARAALEMAIRTNPSYGTAHENLGDIYAKLASQAYDKALQLDSGNTGAKLKLTLIRNLFTNTNSAIATSTKVPPTTVAAAKPITNLPTKASSAKSEPTPTAPVTVATVTKPVVPVVAKAEPAKVEPAKLEPVKLEPAKPAPAKVEPVKAEPTKPEPKAVASNEGQNDVLKVVDAWAAAWSDKNTNAYLAFYSKDFQLPKGSTRKTWAEDRRVRIEGKGHISVKIDAPKVAINGNTATVKFRQIYNSDQLKADSRKTLVLNKQDGKWQIAQERTGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GW79</accession>
    <name>A0A2S9GW79_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ammonium transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">S2091_3303</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the ammonia transporter channel (TC 1.A.11.2) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000017">
        <property type="protein sequence ID" value="PRC91961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91961">
        <property type="protein sequence ID" value="PRC91961"/>
        <property type="gene ID" value="S2091_3303"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008519">
        <property type="term" value="F:ammonium transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3430.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029020">
        <property type="entry name" value="Ammonium/urea_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001905">
        <property type="entry name" value="Ammonium_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018047">
        <property type="entry name" value="Ammonium_transpt_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024041">
        <property type="entry name" value="NH4_transpt_AmtB-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43029">
        <property type="entry name" value="PTHR43029"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00909">
        <property type="entry name" value="Ammonium_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00836">
        <property type="entry name" value="amt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01219">
        <property type="entry name" value="AMMONIUM_TRANSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0924">Ammonia transport</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015596778" description="Ammonium transporter" evidence="9">
        <location>
            <begin position="25"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="79"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="112"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="181"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="209"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="263"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="296"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="328"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="361"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="388"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="416"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="463"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="domain" description="Ammonium_transp" evidence="10">
        <location>
            <begin position="79"/>
            <end position="515"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC91961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="517" mass="53414" checksum="D030A200ED6481AA" modified="2018-07-18" version="1">MKSFLALTLASLVAASCLLGNANADDKVVTPAAAVTASVSASVNVSSPTATPEAPAAIAAAPEVAVVAATPTPNKGDTAWMMVATLLVILMTIPGLALFYGGLVRSKNMLSILMQVFMIFAVIIVLWCIYGYSLAFTQGNSFIGSLFGPDGRLFLNGIFDPAKGTFSTAATFSKGVVIPEFVYVAFQGTFAAITCGLIIGAFAERAKFVAVMSFIVIWFTFSYLPIAHMVWFWPGPDGIKDAATLAIETAKGGWLWKKGALDFAGGTVVHINAAIAGLVGAVMIGRRIGFGKESMAPHSLTMTMIGSSLLWVGWFGFNAGSALEAGDIAALAFINTLLATAAASVSWVLGEWLSKGKPSMLGGASGAVAGLVAITPACGFVGPMGALFIGLLAGLVCLWGVNGLKRLIGADDSLDVFGVHGVGGILGALLTGVFASPALGGQGIFDYVTNKLSADPYSIADQLLIQAEAVLTTVLWSAVVSIIAFKLVDLVIGLRVPEDEEREGLDITSHGESAYHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWB3</accession>
    <name>A0A2S9GWB3_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">UPF0234 protein S2091_3359</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3359</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0234 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000017">
        <property type="protein sequence ID" value="PRC92017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92017">
        <property type="protein sequence ID" value="PRC92017"/>
        <property type="gene ID" value="S2091_3359"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11740">
        <property type="entry name" value="YajQ_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.860">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.990">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00632">
        <property type="entry name" value="UPF0234"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007551">
        <property type="entry name" value="DUF520"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035571">
        <property type="entry name" value="UPF0234-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035570">
        <property type="entry name" value="UPF0234_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036183">
        <property type="entry name" value="YajQ-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30476">
        <property type="entry name" value="PTHR30476"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04461">
        <property type="entry name" value="DUF520"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89963">
        <property type="entry name" value="SSF89963"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="163" mass="18384" checksum="C630E5D88811AC35" modified="2018-07-18" version="1">MPSFDTVSEASMEEVKNAVTQSNKVITNRFDLKGTSAKIELKEKEREVIVFGDSDFHLEQIIIELTQTMGKRKVDVRFLDMGKIDKIGGDKVKQVIKIKNGIESDDAKKIVKVIKDSKLKVQASIQGDAVRVTGAKRDDLQDAMAMLKKEIKDLPLEFNNFRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWC9</accession>
    <name>A0A2S9GWC9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3371</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000017">
        <property type="protein sequence ID" value="PRC92029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92029">
        <property type="protein sequence ID" value="PRC92029"/>
        <property type="gene ID" value="S2091_3371"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="144" mass="15694" checksum="542E29CC0DC2FA31" modified="2018-07-18" version="1">MVLTNIVPIRTKPPLETEKQATSHIPTIHLQKLTHSIAITGEQTPSTSENPAVPLAPTESPNRLDLEALRNQAVVDDKNRIRSPQEKTQGNETLTGSLETHLADAAERGAKKDCKTTYADNSIFTGLARLIPITYGALTDKCKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWE3</accession>
    <name>A0A2S9GWE3_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 19">UDP-N-acetylenolpyruvoylglucosamine reductase</fullName>
            <ecNumber evidence="6 19">1.3.1.98</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="18 19">UDP-N-acetylmuramate dehydrogenase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19" type="primary">murB</name>
        <name evidence="21" type="ORF">S2091_3360</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21 22">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 19">Cell wall formation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 19">
            <text>NADP(+) + UDP-N-acetyl-alpha-D-muramate = H(+) + NADPH + UDP-N-acetyl-3-O-(1-carboxyvinyl)-alpha-D-glucosamine</text>
            <dbReference type="Rhea" id="RHEA:12248"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:68483"/>
            <dbReference type="ChEBI" id="CHEBI:70757"/>
            <dbReference type="EC" id="1.3.1.98"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 19">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="5 19">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4 19">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="19">Belongs to the MurB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.98" evidence="6 19"/>
    <dbReference type="EMBL" id="PUGF01000017">
        <property type="protein sequence ID" value="PRC92018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92018">
        <property type="protein sequence ID" value="PRC92018"/>
        <property type="gene ID" value="S2091_3360"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008762">
        <property type="term" value="F:UDP-N-acetylmuramate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.78.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00037">
        <property type="entry name" value="MurB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016167">
        <property type="entry name" value="FAD-bd_PCMH_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003170">
        <property type="entry name" value="MurB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011601">
        <property type="entry name" value="MurB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036635">
        <property type="entry name" value="MurB_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21071">
        <property type="entry name" value="PTHR21071"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02873">
        <property type="entry name" value="MurB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="SSF56176"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56194">
        <property type="entry name" value="SSF56194"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00179">
        <property type="entry name" value="murB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="16 19" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="9 19" id="KW-0132">Cell division</keyword>
    <keyword evidence="13 19" id="KW-0133">Cell shape</keyword>
    <keyword evidence="17 19" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="8 19" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11 19" id="KW-0274">FAD</keyword>
    <keyword evidence="10 19" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="12 19" id="KW-0521">NADP</keyword>
    <keyword evidence="15 19" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14 19" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="20">
        <location>
            <begin position="21"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="active site" evidence="19">
        <location>
            <position position="168"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="19">
        <location>
            <position position="240"/>
        </location>
    </feature>
    <feature type="active site" evidence="19">
        <location>
            <position position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00003921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012518"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00015188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00031026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="PRC92018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="340" mass="36598" checksum="3A31C6C7A3CC4E2F" modified="2018-07-18" version="1">MSSSLHLQSAVSLQSFTTFGIAASARHYLRVNELSQLQQISLLPELAGLPRLILGGGSNLILTQDFPGVVVHMALEGRECVSEDAQFVYVRAAAGEVWHDFVQWTLAQGWGGLENLSLIPGSVGAAPIQNIGAYGVEIKDYFHSLSWLEFASGKIHTFTLAECQFAYRDSVFKHALRDQGVILDVTFALAKQWQAKLGYGDVAQALQGIKSPTPKQVSNAICAIRLSKLPDPSVIGNAGSFFKNPLVSVEFRNALIARCPGLVSYLQTDGQYKLAAGWLIEQAGWKGRALGKVAVYAKQALVLVNLGGATGAEVVALAQAIQADVMQKFGVQLEVEPVFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWN3</accession>
    <name>A0A2S9GWN3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3053</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92137">
        <property type="protein sequence ID" value="PRC92137"/>
        <property type="gene ID" value="S2091_3053"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021446">
        <property type="entry name" value="DUF3096"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11295">
        <property type="entry name" value="DUF3096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="30"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="50" mass="5383" checksum="20425ED1A5381951" modified="2018-07-18" version="1">MNLHFSIMPLISLIAGILILVMPKLLHLIIGLYLICIGLIGLVGAGHLHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWN5</accession>
    <name>A0A2S9GWN5_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">ATP-dependent Clp protease ATP-binding subunit ClpX</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">clpX</name>
        <name evidence="9" type="ORF">S2091_3048</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6 7">Belongs to the ClpX chaperone family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92132">
        <property type="protein sequence ID" value="PRC92132"/>
        <property type="gene ID" value="S2091_3048"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.220.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00175">
        <property type="entry name" value="ClpX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019489">
        <property type="entry name" value="Clp_ATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004487">
        <property type="entry name" value="Clp_protease_ATP-bd_su_ClpX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046425">
        <property type="entry name" value="ClpX_bact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010603">
        <property type="entry name" value="Znf_CppX_C4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038366">
        <property type="entry name" value="Znf_CppX_C4_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07724">
        <property type="entry name" value="AAA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10431">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06689">
        <property type="entry name" value="zf-C4_ClpX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01086">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00994">
        <property type="entry name" value="zf-C4_ClpX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00382">
        <property type="entry name" value="clpX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51902">
        <property type="entry name" value="CLPX_ZB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 6 7" id="KW-0143">Chaperone</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 6 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="ClpX-type ZB" evidence="8">
        <location>
            <begin position="3"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="15"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="18"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="37"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="40"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="121"/>
            <end position="128"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC92132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="422" mass="46054" checksum="C7D8BEDA83C737C0" modified="2018-07-18" version="1">MPDKKSSSGEKLLYCSFCGKSQHEVKKLIAGPSVFICDECIDLCNDIIRDEISSIETIGNAKADLPTPAEICELLNQYVIGQSTAKRILSVAVYNHYKRLKYLGKKDDVELAKSNILLVGPTGSGKTLLAQTLARMLNVPFVIADATTLTEAGYVGEDVENIIQKLLQNCNYEVEKAQKGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTMASVPPQGGRKHPNQDFVQIDTTNIMFICGGAFDGLAKLISNRSEKGGIGFSASVKSKVESTSNQHLQEVEPEDLIKFGLIPELVGRLPVVATLNELDEESLIQILIEPKNALIKQYAKLLEMEGAELEIRPSALHAIAKKAIERKAGARGLRSILESALLDVMYDLPNEQNVAKVVIDENTITQGAKPILIYHEKPKASGAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWQ6</accession>
    <name>A0A2S9GWQ6_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">1-deoxy-D-xylulose 5-phosphate reductoisomerase</fullName>
            <shortName evidence="7">DXP reductoisomerase</shortName>
            <ecNumber evidence="7">1.1.1.267</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">1-deoxyxylulose-5-phosphate reductoisomerase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">2-C-methyl-D-erythritol 4-phosphate synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">dxr</name>
        <name evidence="11" type="ORF">S2091_3068</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>2-C-methyl-D-erythritol 4-phosphate + NADP(+) = 1-deoxy-D-xylulose 5-phosphate + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:13717"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:57792"/>
            <dbReference type="ChEBI" id="CHEBI:58262"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.267"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="1 7">Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via DXP pathway; isopentenyl diphosphate from 1-deoxy-D-xylulose 5-phosphate: step 1/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the DXR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.267" evidence="7"/>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92152">
        <property type="protein sequence ID" value="PRC92152"/>
        <property type="gene ID" value="S2091_3068"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00056">
        <property type="reaction ID" value="UER00092"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030604">
        <property type="term" value="F:1-deoxy-D-xylulose-5-phosphate reductoisomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070402">
        <property type="term" value="F:NADPH binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019288">
        <property type="term" value="P:isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016114">
        <property type="term" value="P:terpenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00183">
        <property type="entry name" value="DXP_reductoisom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003821">
        <property type="entry name" value="DXP_reductoisomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013644">
        <property type="entry name" value="DXP_reductoisomerase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013512">
        <property type="entry name" value="DXP_reductoisomerase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026877">
        <property type="entry name" value="DXPR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036169">
        <property type="entry name" value="DXPR_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30525">
        <property type="entry name" value="PTHR30525"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08436">
        <property type="entry name" value="DXP_redisom_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02670">
        <property type="entry name" value="DXP_reductoisom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13288">
        <property type="entry name" value="DXPR_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006205">
        <property type="entry name" value="Dxp_reductismrs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69055">
        <property type="entry name" value="SSF69055"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00243">
        <property type="entry name" value="Dxr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6 7" id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 7" id="KW-0521">NADP</keyword>
    <keyword evidence="5 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DXP_reductoisom" evidence="8">
        <location>
            <begin position="5"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="domain" description="DXP_redisom_C" evidence="9">
        <location>
            <begin position="145"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="domain" description="DXPR_C" evidence="10">
        <location>
            <begin position="265"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="8"/>
            <end position="37"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="124"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="149"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="151"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="180"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="203"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF13288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC92152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="390" mass="41866" checksum="4B9859C80D665F08" modified="2018-07-18" version="1">MKQTITILGSTGSIGVSTLDVISRHSDRYQVVALTAHSRVNELAKQCVQFKPKFAVVGSVDAADALKAILAPYDLNINVLFGEAALCDVARECDVVMAAIVGAAGLAPTMAAAKAGKKVLLANKEALVMSGQLFMDAVRENGATLLPIDSEHNAIFQCLPHDFNLDSAQQGIAKILLTASGGPFLHRPINTLHDVTPEQAIAHPNWVMGKKISIDSATMMNKGLEVIEAHWLFAVPVDQIEVVIHPQSVIHSMVSYVDGSMLAQLGNPDMRTPIAYGLAYPERITSGVPQLDITKIAQLQFEKPDFSRFPCLAIAFDALRAGDTAPAIMNAANEVAVQAFLDKKIGFLMIPELITSVMNKIANSPVIDLDGVMEQDALAREAAMHFIASY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWZ6</accession>
    <name>A0A2S9GWZ6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3156</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92240">
        <property type="protein sequence ID" value="PRC92240"/>
        <property type="gene ID" value="S2091_3156"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005624">
        <property type="entry name" value="PduO/GlcC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038084">
        <property type="entry name" value="PduO/GlcC-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03928">
        <property type="entry name" value="Haem_degrading"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143744">
        <property type="entry name" value="SSF143744"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="135" mass="13963" checksum="CF8BC01FDFF478B1" modified="2018-07-18" version="1">MQTKPVLMLEDVKKIAAAAEAEALANKWAVVISIVDDGGHLLWLQRLDGVAPISSHIAPAKARTAAMGCRESKIYEDMINNGRVSFLSAPLIEGMLEGGVPIMVNGQCVGAVGISGVKSAEDAQIAKAGIAALGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GX43</accession>
    <name>A0A2S9GX43_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Translation initiation factor IF-3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_2948</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the IF-3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92289">
        <property type="protein sequence ID" value="PRC92289"/>
        <property type="gene ID" value="S2091_2948"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036788">
        <property type="entry name" value="T_IF-3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036787">
        <property type="entry name" value="T_IF-3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019813">
        <property type="entry name" value="Translation_initiation_fac3_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001288">
        <property type="entry name" value="Translation_initiation_fac_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019815">
        <property type="entry name" value="Translation_initiation_fac_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019814">
        <property type="entry name" value="Translation_initiation_fac_3_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10938">
        <property type="entry name" value="PTHR10938"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00707">
        <property type="entry name" value="IF3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05198">
        <property type="entry name" value="IF3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54364">
        <property type="entry name" value="SSF54364"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55200">
        <property type="entry name" value="SSF55200"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00168">
        <property type="entry name" value="infC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00938">
        <property type="entry name" value="IF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4 7" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3 4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="IF3_N" evidence="6">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="domain" description="IF3_C" evidence="5">
        <location>
            <begin position="43"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF05198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC92289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="129" mass="15124" checksum="448FB9BCF0317BD0" modified="2018-07-18" version="1">MDLVEIAPNAQPPVCRLMDYGKFKYQEQKKAHETKLKQKVVLVKEVKFRPGTDDGDYNIKLRNLIKFLDDGDKTKITLRFRGREMAHQDIGMRMLERLKGDLEPYGQVEQFPKMEGRQMVMVLAPKKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXC9</accession>
    <name>A0A2S9GXC9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2975</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92316">
        <property type="protein sequence ID" value="PRC92316"/>
        <property type="gene ID" value="S2091_2975"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="45" mass="5197" checksum="477E6094677047F7" modified="2018-07-18" version="1">MGEGLDFQGQEVKIISLAEKVVVKIQLTLNYFGCNLILYKWLMHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXS9</accession>
    <name>A0A2S9GXS9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Peroxiredoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2886</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92511">
        <property type="protein sequence ID" value="PRC92511"/>
        <property type="gene ID" value="S2091_2886"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016209">
        <property type="term" value="F:antioxidant activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000866">
        <property type="entry name" value="AhpC/TSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
        <property type="entry name" value="AhpC-TSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015779065" evidence="1">
        <location>
            <begin position="21"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="2">
        <location>
            <begin position="22"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="180" mass="19578" checksum="A53AEC413D26D4FE" modified="2018-07-18" version="1">MKKFLASTLLATVFVTPSFAALVVGDSAPNFTTQASIAGKEFTFSLAEALKKGPVVLYFYPAAFTTGCTIEAHEFAEAVEQYRALGATVIGVSHDSIETLNKFSVSECRSKFAVAADTDQHIMKSYDAILAKKPEYANRTSYVISPDGKVIYSFTDMAPDKHVENTLAAVRKWKAENSSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXT1</accession>
    <name>A0A2S9GXT1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">GGDEF: diguanylate cyclase (GGDEF) domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_2898</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92523">
        <property type="protein sequence ID" value="PRC92523"/>
        <property type="gene ID" value="S2091_2898"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01948">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001633">
        <property type="entry name" value="EAL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035919">
        <property type="entry name" value="EAL_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00563">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00052">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141868">
        <property type="entry name" value="SSF141868"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50883">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="26"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="57"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="85"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="126"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="158"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="2">
        <location>
            <begin position="196"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="3">
        <location>
            <begin position="270"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="5">
        <location>
            <begin position="354"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="domain" description="EAL" evidence="4">
        <location>
            <begin position="509"/>
            <end position="762"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC92523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="762" mass="84321" checksum="38D91540BDD1CD87" modified="2018-07-18" version="1">MLIQSIRRLIIAPQSELGDIAQWRNYVLSTILLVVLILGTIVAVPSALAALFDKRPAIAISDALAVAWLFALWHSRRLSYRARAWNFCALIYLIGLSLLFSVGPASEIYLMAFPVMVALLLGLRPALFGIALNAFTLLCVGYLFNADLNIQGFEAHPLLRWTIITINFTLINSLITIATVMLLHGLDKSLEKSHDGEALYRATFENAPIGVARLGLDGHWLQVNQKLCDITGYGRQELLGLAFQDITHPLDVAADIAGLEALNHGEIKSFDREKRYVRKDGSHIFVHVHSSVVRNAAGIARYVISVATDITERRVAESKIHTLAFYDVLTQLPNRRLLVDRLGHALAGCKRSRRQGAIMFIDMDNFKTLNDIHGHDVGDRLLVEVARRLQSSVRQGDTVARLGGDDFVVMVEDLLPDTLAASQAETVAQKILTVLNEPFNLELKMGADRHKSIEYHCSASIGISLFGEYEDMVDELLKQADLAVYQAKDSGRNTVRFFDRDMQAKVAARATLTEDLREAVSAEQFMIYYQAQVQEDGCVTGVEALVRWRHPQRGVVSPAEFIPLAEETGLIVPLGQWVLQTACVQLADWAAVSETAHLSIAVNVSARQFAQHHFVDEVLTVLESSGANPQRLKLELTESLLIMNVDEVIEKMSALKARGVCFSLDDFGTGYSSLSYLKRLPLDQLKIDQSFVRDVLSDPNDAAIAKTIIALGKSLGLGVIAEGVETSAQRDFLASCGCHAYQGYLYGRPMPIQEFKSFHITD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXU5</accession>
    <name>A0A2S9GXU5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cytochrome B561</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_2600</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92545">
        <property type="protein sequence ID" value="PRC92545"/>
        <property type="gene ID" value="S2091_2600"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022904">
        <property type="term" value="P:respiratory electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011577">
        <property type="entry name" value="Cyt_b561_bac/Ni-Hgenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016174">
        <property type="entry name" value="Di-haem_cyt_TM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01292">
        <property type="entry name" value="Ni_hydr_CYTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81342">
        <property type="entry name" value="SSF81342"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="49"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="95"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="150"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="domain" description="Ni_hydr_CYTB" evidence="3">
        <location>
            <begin position="9"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC92545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="182" mass="20456" checksum="77FF66680B3E1959" modified="2018-07-18" version="1">MAYLNTKERYGSLSIGLHWLMLLVLAGVYTCVELHDFFPKGSEMRSGLMTWHFSLGVTIFLLVCVRLVLRVIAPEPVIKPAITVWQKWSAKLMHWALYLLMIGMPIAGCLGRAAAGKVTYFFGIALPSLIGPNKELAETIFDWHETIGNLGYFLIGAHALAALFHHYVQRDNTLVRMLPKRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GY13</accession>
    <name>A0A2S9GY13_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Transcription-repair-coupling factor</fullName>
            <shortName evidence="8">TRCF</shortName>
            <ecNumber evidence="8">3.6.4.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">mfd</name>
        <name evidence="11" type="ORF">S2091_2653</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">In the C-terminal section; belongs to the helicase family. RecG subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">In the N-terminal section; belongs to the UvrB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.-" evidence="8"/>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92598">
        <property type="protein sequence ID" value="PRC92598"/>
        <property type="gene ID" value="S2091_2653"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009380">
        <property type="term" value="C:excinuclease repair complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000716">
        <property type="term" value="P:transcription-coupled nucleotide-excision repair, DNA damage recognition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00969">
        <property type="entry name" value="TRCF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036101">
        <property type="entry name" value="CarD-like/TRCF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003711">
        <property type="entry name" value="CarD-like/TRCF_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004576">
        <property type="entry name" value="Mfd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037235">
        <property type="entry name" value="TRCF-like_C_D7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005118">
        <property type="entry name" value="TRCF_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004807">
        <property type="entry name" value="UvrB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041471">
        <property type="entry name" value="UvrB_inter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24029">
        <property type="entry name" value="PTHR24029"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02559">
        <property type="entry name" value="CarD_CdnL_TRCF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03461">
        <property type="entry name" value="TRCF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17757">
        <property type="entry name" value="UvrB_inter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01058">
        <property type="entry name" value="CarD_TRCF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00982">
        <property type="entry name" value="TRCF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141259">
        <property type="entry name" value="SSF141259"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143517">
        <property type="entry name" value="SSF143517"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00580">
        <property type="entry name" value="mfd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 8" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7 8" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0347">Helicase</keyword>
    <keyword evidence="3 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="9">
        <location>
            <begin position="617"/>
            <end position="778"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="10">
        <location>
            <begin position="799"/>
            <end position="953"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC92598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="1144" mass="127777" checksum="4B68BBA84654D4EA" modified="2018-07-18" version="1">MSFDLLSPPKPGYRITFPALHGSADSYALSQTATELKAQKRMLTIFVADATDAQRLQSEISWFGNEAKLRCHVLPDWETLPYDAFSPHQDLVSERLATLYEVGHGQSDVLIVPVSTALIRMAPPSFLAAYTFFFKQGATLNEAQLKSQLTLAGYSHVSQVMSPGEYAVRGGLIDLFPMGSPLPYRLDLFGETIETIRTFDADTQRTIYPVAEVRLLPGREFPMDDVARTAFRKRWREEFEGDPSRTRIYKDIGNGIASAGIEYYLPLFFDNTATLFDYLPETTCICMVGEIDAAIASFWADTQSRYTFLKADRERPVLAPETLFLRDEAFFTLAKPYGRYIIKPNATVLDGVSSALPDIAVNRRLDDPLTNLRSYLLQTKQRVLLCAESNGRRETLQQYFNEYDLHPVICDSLTDFITGDAPLMLGVAPLYAGFNLDNGLSFITETELYANVVRRPSSGRKKQEGATQVESMVRDLSELKIGDPVVHVHYGIGRYHGLVAMDLGEGETEFLHLEYAKETKLYVPVAQLHVISRYSGASQEDAPLHMLGSGSWEKAKRKAAQQCRDTAAELLNLYARRALREGHAFEYSAHDYHAFAESFGFEETVDQAAAINAVVSDMTSGKPMDRLICGDVGFGKTEVALRAAFVAVMGGKQVAILAPTTLLAEQHAQTFADRFADWPVKIAELSRFRSGKEITAAIKGMNDGTVDIVIGTHKLLSDDIKFNRLGLVIIDEEHRFGVRQKETLKALRAEVDVLTLTATPIPRTLGMALEGLRDFSIIATAPQKRLAIKTFVRSEDDSVLREACLRELKRGGQVYFLHNEVDTIQNRKAMLEKLLPEARIAVAHGQMHERDLEKVMRDFVAQRYNILLCTTIIETGIDVPTANTIIMHRADKFGLAQLHQLRGRVGRSHHQAYAYLLVHDVKGLTKLAQRRLDAIVEMEELGSGFYLAMHDLEIRGAGEVLGDNQSGEMIEIGFSLYSEMLSEAVRCLKEGKEPDLAAPLATTTEINLHTPALLPNEFCGDVHERLSLYKRLSNASSFEAIDTLQEELIDRFGKLPEPVSALIETHRLRVLAKTVGIFKIDAHSDAAIMQFIEKPPIDPMRIIDLIQKNRHIKLHGPDKLRITVNMPDLAARVGQIKAAIRALK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GY32</accession>
    <name>A0A2S9GY32_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Formylglycine-generating sulfatase enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2689</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92634">
        <property type="protein sequence ID" value="PRC92634"/>
        <property type="gene ID" value="S2091_2689"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005532">
        <property type="entry name" value="SUMF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042095">
        <property type="entry name" value="SUMF_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03781">
        <property type="entry name" value="FGE-sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="SSF56436"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FGE-sulfatase" evidence="1">
        <location>
            <begin position="93"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="289" mass="31130" checksum="53B6E25691569A16" modified="2018-07-18" version="1">MQVELIQEATFTLRAGTKAVHGLFHVSEWEGMNKYQNSAGHILILNNGKVIKGSPELLASLADVPAGFVQVPETNLPCGLIVPAFKVAQHISTKSTNGTVSFDPTLKPWTNISFYDAQKACEAAGYNMITETQWLAIGHNLSQQDCNWTGGKVGEGDLYQGIRKGGGAKPGDYVPTDATERRWMTLSNGAQVCDFNGNVFQWVFDNVQGNEKGVAAKAFEAHSPSLTTAGYPSQTKGVGYRPNAGCDWSGYALVRGGYWRSGDYAGVFRLGYGGPVYGVDGVGFRCTIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GY67</accession>
    <name>A0A2S9GY67_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2722</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92667">
        <property type="protein sequence ID" value="PRC92667"/>
        <property type="gene ID" value="S2091_2722"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="217"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="39"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="218"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="262" mass="28084" checksum="5DD7A0B53C22BE37" modified="2018-07-18" version="1">MKIKLDDKGNVVVQDGKVVYVYDDGKEVAFDAVSTVAKINGLNGEAKAHRERAEAAETKLKSFEGIADPEIARKALETIKNIDDKKLVDAGKVEEVRAAAVKAYEDKLVAANQTHAEQMAKLHVDLERANGDLHSEKIGGSFNRSKLITEKFAIPADLVQARFGSAFKIEEGKIVAKDNAGNKIFSRSRPGDLADFDEALEILVDQYPYKDQILKGSGATGSGATGGNQGASGKKTIPRSQFDAMDAGSRATAMRDGATVTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GY72</accession>
    <name>A0A2S9GY72_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2705</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92650">
        <property type="protein sequence ID" value="PRC92650"/>
        <property type="gene ID" value="S2091_2705"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="103" mass="11369" checksum="FD18B764CFBE43FC" modified="2018-07-18" version="1">MKSLHSETKSESFHSLSIPEYLQPAEKRIIALFNNTSIALTRKQIRDALGDMELSGVCGRVNSLITKNRLANRGERKDPKTRKSQGLVGLPVSVQFSLIGFAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYC5</accession>
    <name>A0A2S9GYC5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2455</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92725">
        <property type="protein sequence ID" value="PRC92725"/>
        <property type="gene ID" value="S2091_2455"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="29"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="57"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="112" mass="12084" checksum="4FF7A31B45102E5A" modified="2018-07-18" version="1">MATGKQIQAEKPNLGNDRPAVHMFTSSDIFLFFPEIIPAAILAVWSPFWAIQLLLESHFLAALTLLCGVGASGYAFYSGVRSKQKYLAYIGVLGMLLSAGLALQLSQHVVAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYC6</accession>
    <name>A0A2S9GYC6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Type II secretory pathway ATPase PulE/Tfp pilus assembly pathway</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2755</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GSP E family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92700">
        <property type="protein sequence ID" value="PRC92700"/>
        <property type="gene ID" value="S2091_2755"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001482">
        <property type="entry name" value="T2SS/T4SS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037257">
        <property type="entry name" value="T2SS_E_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007831">
        <property type="entry name" value="T2SS_GspE_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00437">
        <property type="entry name" value="T2SSE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05157">
        <property type="entry name" value="T2SSE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160246">
        <property type="entry name" value="SSF160246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00662">
        <property type="entry name" value="T2SP_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="T2SP_E" evidence="2">
        <location>
            <begin position="378"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS00662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="561" mass="61299" checksum="F5F810A5D997D0A1" modified="2018-07-18" version="1">MNDIIAPPTIDTALIQQARLQAAKSHRSIMIELEAMTQSDPRSLVQAVAKPFGLTVIETAEMLALAPAFDLLPLSRAMQRYCVLLRSADERIIGVIADPFDADLPIWLEAQAGGALEICFALQADIQAYLSKLEESARAVDNLGPTTDATRRDSKTATVLSFASVSEAASPAVKLINSTLYDALKAGASDIHLESTASGLAVKYRVDGVLDHAASANGTETAEHVISRLKVLAELDIAERRIPQDGSFRVESGGREIDLRVSIMPSIHGEDAVIRILDKRAMIEAYGALTLEALGFDAPSLITLRGLAEEAYGMLLVTGPTGSGKTTTLYAALTEIHNGRDKIITIEDPVEYQLPGILQIPVNEKKGLTFAKGLRSILRHDPDKIMVGEIRDKETAEIAVQSALTGHLVLTTVHANNVFDVFGRFTHMGIDPYAFVSALNGIWAQRLIRLNCPHCATSYIPTELELERVHLQRDECHDYVFKQGKGCGDCRGTGYKGRRAIAEILTLTDEIREMVIEKRPIRQIKEAARKNGTRSLREAALELVKRSETTLSEIKRVTLHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYJ4</accession>
    <name>A0A2S9GYJ4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92770">
        <property type="protein sequence ID" value="PRC92770"/>
        <property type="gene ID" value="S2091_2500"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="162" mass="18946" checksum="0D3C6A846C98F273" modified="2018-07-18" version="1">MPRQTILREQVLAFWESERWAREWFDHKGYDHFDFPQTPGTMPISLSKCGGKRPDFAFSLNENESLVYVDAKFHATNNITEFGLTVEELKKYEAFKKWALNELQDDGERDIILMLYPQELNGDRFTWILLDELLAEEDTIIDGKPAKKASLLGREDFWIGNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYP0</accession>
    <name>A0A2S9GYP0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2572</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92842">
        <property type="protein sequence ID" value="PRC92842"/>
        <property type="gene ID" value="S2091_2572"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07377">
        <property type="entry name" value="WHTH_GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00392">
        <property type="entry name" value="GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50949">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="1">
        <location>
            <begin position="17"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="132" mass="14537" checksum="6ADCAE518B03ADEC" modified="2018-07-18" version="1">MPDPSTQLFSVAVGSSEPIYRQLIEQVTRLVASGNLQSGQTLPSVRDMANALAVNPMTISKAYSMLEANGVLERQRGIGMVIAHHKNNIQKIQHRVELLNPTMEKLIFEANQLELDADTVITQLTILLKGSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYU8</accession>
    <name>A0A2S9GYU8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative translation initiation inhibitor yjgF family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2309</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92892">
        <property type="protein sequence ID" value="PRC92892"/>
        <property type="gene ID" value="S2091_2309"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02199">
        <property type="entry name" value="YjgF_YER057c_UK114_like_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013813">
        <property type="entry name" value="Endoribo_LPSP/chorism_mut-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035959">
        <property type="entry name" value="RutC-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14588">
        <property type="entry name" value="YjgF_endoribonc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55298">
        <property type="entry name" value="SSF55298"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YjgF_endoribonc" evidence="1">
        <location>
            <begin position="7"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="162" mass="17240" checksum="B2B9779BE8E73BEF" modified="2018-07-18" version="1">MSIITDRLTFMGLTLPPPVQAPAGVIIPFQFVHVVGQRVFISGHGPQQSDGAIAQPLGKVGGELTLEQGYMAARLTALSILGSLHRKLGNLDRIAAFTRVFGMVNSAPGFCQQPSVINGFSDLILELFGSEIGAHSRSAVGMAELPFNIPVEIEAEVLLYPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYX6</accession>
    <name>A0A2S9GYX6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Polyhydroxyalkanoate depolymerase, intracellular</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2356</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92939">
        <property type="protein sequence ID" value="PRC92939"/>
        <property type="gene ID" value="S2091_2356"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009656">
        <property type="entry name" value="PHB_depo_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010915">
        <property type="entry name" value="PHB_depoly_PhaZ"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06850">
        <property type="entry name" value="PHB_depo_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF020818">
        <property type="entry name" value="PHB_depoly_PhaZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01849">
        <property type="entry name" value="PHB_depoly_PhaZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PHB_depo_C" evidence="1">
        <location>
            <begin position="202"/>
            <end position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="404" mass="45631" checksum="508241FFC93276E4" modified="2018-07-18" version="1">MNRALITPLTHWAEASSKLFSNPISPLAHTPFSQRIAAGYELMFRLGKSYEKPAFNIDSTIVNGQTVAIVEEVELQKSFCTLIHFKKVLSSKEIKQLDQPKVLLVAPLSGHHSTLLRDTVRALLTHHDVYITDWTDARMVPLAEGEFHLHDYIYYVQDFIRHLAPNLHVISVCQPTVPVLAAISLMATAKDPKLPKTMTMMGGPIDPRKSPTQVNNLAVEKPYSWFENNVIYSVPPNFPGNGRKVYPGFLQHTGFVAMNPRRHAQSHWDFYQHLIKGDDDPAEAHRQFYDEYNAVLDMPAGYYLDTIKTVFQEFSLPKGTWEVEGKLVRPQDIKTVALFTVEGELDDISGPGQTQAAHDICTGIPANRQQDFVAPNCGHYGIFSGRRWREVVCPKITEFIQKHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYZ0</accession>
    <name>A0A2S9GYZ0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cytochrome c553</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_2348</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92931">
        <property type="protein sequence ID" value="PRC92931"/>
        <property type="gene ID" value="S2091_2348"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13442">
        <property type="entry name" value="Cytochrome_CBB3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0349">Heme</keyword>
    <keyword evidence="3 4" id="KW-0408">Iron</keyword>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015497655" evidence="5">
        <location>
            <begin position="20"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="6">
        <location>
            <begin position="20"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC92931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="106" mass="11273" checksum="DB305AF2FD690907" modified="2018-07-18" version="1">MKKIFALVALLSMVNVALAADVVGNAKAAENKVAMCIGCHGIPGYKATFPEVYQVPMLGGQSAKYLESALNAYKKGDRKHPTMHGIAASLSDQDIADLAAYYAQQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZF0</accession>
    <name>A0A2S9GZF0_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ATP-dependent Clp protease proteolytic subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2166</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the peptidase S14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93080">
        <property type="protein sequence ID" value="PRC93080"/>
        <property type="gene ID" value="S2091_2166"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001907">
        <property type="entry name" value="ClpP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023562">
        <property type="entry name" value="ClpP/TepA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10381">
        <property type="entry name" value="PTHR10381"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00574">
        <property type="entry name" value="CLP_protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00127">
        <property type="entry name" value="CLPPROTEASEP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="279" mass="29698" checksum="23E2456348DBBCE6" modified="2018-07-18" version="1">MSLLTLPKINAEARIGNAQFDMRTDALERWEPTICASTDNSTSISIYEQIGESWDGSGMTAARMSGILRNVGNSEIVVNINSPGGDFFEGVAIYNLLREHKAKVTIKVVGLAASAASIIAMAGDEIQMGDGAFLMIHNAWAVAVGNRHDLKAAAETLTPFDEAMADVYAARSGLSAKEAAKLMDAETWLNASKAVEQGFATGLMQRDEITHNAKAQGNTKHLALVEAAMARAGHSRSVRRDTLKSLFSSKPGAAENTVKPSADIAASLQSLLQTMKEST</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZL3</accession>
    <name>A0A2S9GZL3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2261</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93175">
        <property type="protein sequence ID" value="PRC93175"/>
        <property type="gene ID" value="S2091_2261"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015641219" evidence="1">
        <location>
            <begin position="21"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="174" mass="19485" checksum="8B1B7C07C259E762" modified="2018-07-18" version="1">MKFLVSVLACVLFQSGSANAATPSYLENHATSSEDFSSITKLIGDFGTAIKTKNPKLLSTLVLNNKVLFMSPWPVEDIKEAQNGWDTTFDGTYPDGYSTFVKLLKTEKSPIEEKFYNVKITQDDNLAWVMSDFEFMKEGVTLNHGVKVWQLMKSVDGNWKILSVVWSSKGKPSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZL9</accession>
    <name>A0A2S9GZL9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">LysR substrate binding domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2257</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93171">
        <property type="protein sequence ID" value="PRC93171"/>
        <property type="gene ID" value="S2091_2257"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="317" mass="35224" checksum="3CE1C904E16265AC" modified="2018-07-18" version="1">MNLNQLRFAHAVATTGSFTAAAAECFVTQPTLSNGIAQFEEELGERLFVRTTRKVTLTAFGIHILPCIIDVLSAQATLVHQAQAFLQPEKRLIRIGTSPLINANLLGLMIEPFQRENPAVDVVLREMNMEDLYRMLDSDQLDFVFGITNTHKGSWDSTFLYQEPLLFIPRLAELHKSPHAQSVQFKDISDETYVMVPDGCGLSRATRALFRSHRRKLNEYAGQAMSYQVLEEWAMLGIGAAILPKSKVSDKTQHALPITDKAGVDVVLDFQAIWSRKGLQLPHLFAFSNHLSQVVPAVVAGLGLGMKNESQASYQSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZM7</accession>
    <name>A0A2S9GZM7_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Tryptophan synthase beta chain</fullName>
            <ecNumber evidence="11">4.2.1.20</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">trpB</name>
        <name evidence="14" type="ORF">S2091_2244</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate + L-serine = D-glyceraldehyde 3-phosphate + H2O + L-tryptophan</text>
            <dbReference type="Rhea" id="RHEA:10532"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:57912"/>
            <dbReference type="ChEBI" id="CHEBI:58866"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="4.2.1.20"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 11">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 11">Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 5/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5 11">Tetramer of two alpha and two beta chains.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 11">Belongs to the TrpB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.20" evidence="11"/>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93158">
        <property type="protein sequence ID" value="PRC93158"/>
        <property type="gene ID" value="S2091_2244"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00035">
        <property type="reaction ID" value="UER00044"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004834">
        <property type="term" value="F:tryptophan synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06446">
        <property type="entry name" value="Trp-synth_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00133">
        <property type="entry name" value="Trp_synth_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="PLP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006653">
        <property type="entry name" value="Trp_synth_b_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006654">
        <property type="entry name" value="Trp_synth_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023026">
        <property type="entry name" value="Trp_synth_beta/beta-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="Trypto_synt_PLP_dependent"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001413">
        <property type="entry name" value="Trp_syn_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="SSF53686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00263">
        <property type="entry name" value="trpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00168">
        <property type="entry name" value="TRP_SYNTHASE_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9 11" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="10 11" id="KW-0456">Lyase</keyword>
    <keyword evidence="8 11" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 11" id="KW-0822">Tryptophan biosynthesis</keyword>
    <feature type="domain" description="PALP" evidence="13">
        <location>
            <begin position="77"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="11">
        <location>
            <position position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="PRC93158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="418" mass="45056" checksum="BD846560D2615858" modified="2018-07-18" version="1">MPSNMNPNQNPSNTATAATSPHYQLPDERGHFGIYGGSFVSETLSHALNQLTDAYAYYSQDAEFLAEYHSELKHFVGRPSPIYHAKRWSSELGGAQIYLKREDLNHTGAHKINNVIGQALLAKRMGKPRVIAETGAGQHGVATATICARFGLECVVYMGSEDVARQAQNVYRMKLLGATVVPVDSGSKTLKDALNEAMRDWVANVDNTFYIIGTVAGPHPYPKMVRDFQVVIGNECLVQMPEMTGRQPDAVIACVGGGSNAMGIFHPYIDYADVQLIGVEAAGDGLETGRHAASLTAGSPGVLHGNRTYLLQDKNGQVIETHSVSAGLDYPGVGPEHAWLKDSGRAQYVTITDQEALKAFHDCCRIEGIIPALESSHAIAYATKLAATLAKDKLLLVNLSGRGDKDMHTVAQQAGIKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZP4</accession>
    <name>A0A2S9GZP4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lactonase, 7-bladed beta-propeller</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1943</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93205">
        <property type="protein sequence ID" value="PRC93205"/>
        <property type="gene ID" value="S2091_1943"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019405">
        <property type="entry name" value="Lactonase_7-beta_prop"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10282">
        <property type="entry name" value="Lactonase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015392793" evidence="1">
        <location>
            <begin position="30"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="406" mass="40210" checksum="D8D961137B1F9E5B" modified="2018-07-18" version="1">MKHSPQLSAPRILGGITISCLLAALSACGGSSSSTPATTSNATAPVIAPPLANQLYTQSNETANVIVHFSRSATGAITVVDRTSTGGVGTNGIKSGGAPAAPGPDTLASQHSVIISPDKSTLFAVNAGDNSISVFAINQTTGSLTLEKNTSTNGLTPNSLAFNNGYLYVTFQGGSDQLGAYQVGSGGGLTQVGLYSLAVAGAAPNQVVISPNGSFVVVSAGHAANAIVSYPINGDGSLATPIVNVTGNTPFAGAFMQTASNWVYLSTNIGGMGLGSFSFSTSGALTAIASGTSGVAAPCWLSITPNNQFAYVGNGAGAISSYSVTTAGAVSLLSAQAATEPSAITGVNSVAADSWVSPDGLYLYSDYLGDDKVVAYSISSTGVLTKINQAVLGTATGLSMQGLVGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZP7</accession>
    <name>A0A2S9GZP7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1942</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93204">
        <property type="protein sequence ID" value="PRC93204"/>
        <property type="gene ID" value="S2091_1942"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="37" mass="4316" checksum="9B686FFDEDA9FAF9" modified="2018-07-18" version="1">MSKAQDSKKAVKKEPAKTMKEKKADKKVKKEEKKRVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZQ2</accession>
    <name>A0A2S9GZQ2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Prokaryotic homologs of the JAB domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_2182</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C40 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93096">
        <property type="protein sequence ID" value="PRC93096"/>
        <property type="gene ID" value="S2091_2182"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070122">
        <property type="term" value="F:isopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140492">
        <property type="term" value="F:metal-dependent deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028090">
        <property type="entry name" value="JAB_dom_prok"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000555">
        <property type="entry name" value="JAMM/MPN+_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000064">
        <property type="entry name" value="NLP_P60_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00877">
        <property type="entry name" value="NLPC_P60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14464">
        <property type="entry name" value="Prok-JAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00232">
        <property type="entry name" value="JAB_MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="SSF54001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51935">
        <property type="entry name" value="NLPC_P60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="NlpC/P60" evidence="7">
        <location>
            <begin position="103"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC93096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="244" mass="27335" checksum="F1F69D2ED1608444" modified="2018-07-18" version="1">MKPKTLTDIKRHAEADYPREACGLIIIRRGREKYLPCKNLAPDTEHFIISAQDYAVAEEMGEIVAVVHSHPDAPASPSEADKVSCEASGVLWHIIRVDGTEGIPTAGELITIEPCGYQVPLVGRQFFHGVLDCYSLIRDWYQQTRSIELKQFSRADEWWNDGKSDLYTQGFPQAGFVSIESNAEMQVGDVILMQIRSTNGVPNHAAIYIGDGLILHHLHGHLSSRDVYGGYWQEVTRNVIRYVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZU6</accession>
    <name>A0A2S9GZU6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1992</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93254">
        <property type="protein sequence ID" value="PRC93254"/>
        <property type="gene ID" value="S2091_1992"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="41" mass="4789" checksum="3D547FA884632BF7" modified="2018-07-18" version="1">MLAQKLYMNENIVIGKSIFPNGCNKLIHFDVLSLFHFLCYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZZ9</accession>
    <name>A0A2S9GZZ9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cytochrome c</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_1934</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="PTM">
        <text evidence="4">Binds 2 heme c groups covalently per subunit.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93196">
        <property type="protein sequence ID" value="PRC93196"/>
        <property type="gene ID" value="S2091_1934"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024167">
        <property type="entry name" value="Cytochrome_c4-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00034">
        <property type="entry name" value="Cytochrom_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13442">
        <property type="entry name" value="Cytochrome_CBB3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000005">
        <property type="entry name" value="Cytochrome_c4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4 6" id="KW-0349">Heme</keyword>
    <keyword evidence="3 5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="2 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cytochrome c" evidence="7">
        <location>
            <begin position="36"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="7">
        <location>
            <begin position="133"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="binding site" description="covalent" evidence="4">
        <location>
            <position position="50"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="4">
        <location>
            <position position="53"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="54"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="97"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="covalent" evidence="4">
        <location>
            <position position="154"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="4">
        <location>
            <position position="157"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="158"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>2</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="198"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>2</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000005-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000005-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC93196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="225" mass="23977" checksum="54DAED4E85FD8FAE" modified="2018-07-18" version="1">MNILTMNHLNLSKLVALSAILAISACSSPERSRNLNDASIPVSTTALQVCSNCHGMHGVSTSPNFPNLAAQTQPYIVNQLTAFRSHGRSDPEGFEYMWGLSSHLSDAQINGLASYFSSLPPPSGNVDKAGTPAMLTDGRTIFEQGIEAQSVPACSACHGAHAEGADQFPRLAGQHADYLVKQLMVFQLTNQRPDGIAMKAVTHNLTPESIANVAAYLESMAPMPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H022</accession>
    <name>A0A2S9H022_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">BON domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2038</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93300">
        <property type="protein sequence ID" value="PRC93300"/>
        <property type="gene ID" value="S2091_2038"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007055">
        <property type="entry name" value="BON_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014004">
        <property type="entry name" value="Transpt-assoc_nodulatn_dom_bac"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04972">
        <property type="entry name" value="BON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00749">
        <property type="entry name" value="BON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50914">
        <property type="entry name" value="BON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015652730" evidence="1">
        <location>
            <begin position="26"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="BON" evidence="2">
        <location>
            <begin position="47"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="116" mass="12074" checksum="E2CC6A824D1D7901" modified="2018-07-18" version="1">MQNRKMIVPFITAALLSAVSISSFAQQPPAEPTGQPGMVEKAGVVVEDSVITTKVKSALVADKDVSALKINVTTKQGVVMLTGAAPTVEAIKHVLQLVAAIDGVKDIESHLQVKAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H030</accession>
    <name>A0A2S9H030_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">AcCoA-C-Actrans: acetyl-CoA C-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_2080</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the thiolase-like superfamily. Thiolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93342">
        <property type="protein sequence ID" value="PRC93342"/>
        <property type="gene ID" value="S2091_2080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00751">
        <property type="entry name" value="thiolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002155">
        <property type="entry name" value="Thiolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020610">
        <property type="entry name" value="Thiolase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020617">
        <property type="entry name" value="Thiolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020616">
        <property type="entry name" value="Thiolase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02803">
        <property type="entry name" value="Thiolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00108">
        <property type="entry name" value="Thiolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000429">
        <property type="entry name" value="Ac-CoA_Ac_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01930">
        <property type="entry name" value="AcCoA-C-Actrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00099">
        <property type="entry name" value="THIOLASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thiolase_N" evidence="4">
        <location>
            <begin position="3"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="domain" description="Thiolase_C" evidence="5">
        <location>
            <begin position="275"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-thioester intermediate" evidence="2">
        <location>
            <position position="87"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="353"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000429-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC93342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="397" mass="41315" checksum="1BBEB1059C98B82C" modified="2018-07-18" version="1">MNIVIVGAARTPMGAFQGDFSSVTASQLGAVAIKAALERSGVKPEMVDEVLFGNCLMAGQGQAPARQATLAAGLPISVGAVTLSKMCGSAMKAAMMAHDSILAGTNHIVVAGGMESMTNAPYLLPKARGGYRIGHGQVMDHMMLDGLEDAYSRDEKSGGGRSMGTFAEECSAKYNFSREDQDAFAIESVKRAQAATADGSFAWEIAPVTVKGRSGDVVIDKDEGPLKAKLDKIPTLKPAFKKDGTITAASSSSINDGAAALIMMSEETAKKLGCKILARVVGHATHAQEPNWFTTAPVGAMQKLFKKTGWSVKDVDLFEINEAFATVPMAAMREFDIPHSKVNVHGGACALGHPIGASGARIICTLIGALQKRGLKRGVATLCIGGGEGTAMAIELA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H031</accession>
    <name>A0A2S9H031_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2048</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93310">
        <property type="protein sequence ID" value="PRC93310"/>
        <property type="gene ID" value="S2091_2048"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="294" mass="32795" checksum="0A2C14BD9BE13DC3" modified="2018-07-18" version="1">MDRLLSMEVFVAVVESGSLTAAAELFGISPPMVGKHIRHLEQRLGASLLSRTTRRQNLTEIGRSYYPRCKALLEELRATEAGTQAMQATPRGHLRLSTTVTYGSIQLAPLLTEYLNNYPDISVELTLNDQVVDLIEEGYDAVIRVGELADSNLIARPLQPYHMAVCAAPSYLTKHGTPVTPEQLTNHQCLNFTHSNQRVEWRLQQADGEFSTQSNGRFQSNNGQALRMAALQGFGIIMQPQLLVADDLVQGHLVSILSDYLAPPRPVHLVYLRDRQQVPKLSTFIEFMMQRLGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H033</accession>
    <name>A0A2S9H033_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2065</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93327">
        <property type="protein sequence ID" value="PRC93327"/>
        <property type="gene ID" value="S2091_2065"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023631">
        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01425">
        <property type="entry name" value="Amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="SSF75304"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Amidase" evidence="1">
        <location>
            <begin position="65"/>
            <end position="512"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="537" mass="56919" checksum="444221E09A8E3D97" modified="2018-07-18" version="1">MDRRLFVKLGLLIGAANSINNDADAAVSSSSKSEAHLANNHSLIDADVIELQALMSSGKLSAKSLTEQYLQRIKTIDRAGPHLNSIIELNPDALAIATALDAERKVSGARGPLHGIPVLIKDNIATADKMQTTAGSLALVGARAPRDAFLVKQLRAAGAVILGKTNLSEWANMRSTRSTSGWSGRGGLTKNPYALDRNCSGSSSGSAAAIAASLATLAVGTETDGSIVSPASLCSLVGIKPTLGLISRDGIVPIAHSQDTAGPMTRTVSDAALLLTVLAGIDARDSATASSRGRATDYTKFLDKNGLKGARIGVTRNAMSSNLRQQAVVDEALEVLKQQGAILIDVELPNIAKYTDSELEVLLYELKADLNRYLAEFGQGCAVNSLADVIAFNEKNRSREMPYFDQELLIKAQEKGDLNSPAYLIALENNHQYSRVEGIDQIMREHQLDALFASTGGPAWISDYVNGDHVIDGFSTPAAVAGYPHITVPAGFFAGLPVGVSFIAGQYAEGMLIKLAYAYEQASKRRKVPTYMAHSLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H071</accession>
    <name>A0A2S9H071_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1766</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93379">
        <property type="protein sequence ID" value="PRC93379"/>
        <property type="gene ID" value="S2091_1766"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="26"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="80" mass="9227" checksum="CC9F35290B2B8110" modified="2018-07-18" version="1">MTPLSSKNLLPHWCTHWRNHSLKWEITIALIVKISLLWLLWQFFFSAPQAKHMHLPEPQVSQHLLSGTPLPSPQPASTPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0H4</accession>
    <name>A0A2S9H0H4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CcoS: cytochrome oxidase maturation protein, cbb3-type</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1869</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93482">
        <property type="protein sequence ID" value="PRC93482"/>
        <property type="gene ID" value="S2091_1869"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004714">
        <property type="entry name" value="Cyt_oxidase_maturation_cbb3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41532">
        <property type="entry name" value="PTHR41532"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03597">
        <property type="entry name" value="FixS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00847">
        <property type="entry name" value="ccoS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="57" mass="6339" checksum="7B98C49EA165D2C7" modified="2018-07-18" version="1">MEALYLLIPLSIVIVFVAICIFFCMSDSGQFDDMVGPALRILHDDDKPAQSEQLPPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0J8</accession>
    <name>A0A2S9H0J8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Heavy metal translocating P-type ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_1870</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93483">
        <property type="protein sequence ID" value="PRC93483"/>
        <property type="gene ID" value="S2091_1870"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019829">
        <property type="term" value="F:ATPase-coupled cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00371">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021993">
        <property type="entry name" value="ATPase-cat-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006121">
        <property type="entry name" value="HMA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036163">
        <property type="entry name" value="HMA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027256">
        <property type="entry name" value="P-typ_ATPase_IB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12156">
        <property type="entry name" value="ATPase-cat_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00403">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55008">
        <property type="entry name" value="SSF55008"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="SSF81653"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="SSF81665"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01525">
        <property type="entry name" value="ATPase-IB_hvy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50846">
        <property type="entry name" value="HMA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-1278">Translocase</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="198"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="230"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="267"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="291"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="447"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="475"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="784"/>
            <end position="800"/>
        </location>
    </feature>
    <feature type="domain" description="HMA" evidence="7">
        <location>
            <begin position="111"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC93483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="845" mass="90345" checksum="AEBEE0B77ECC9A33" modified="2018-07-18" version="1">MNAVGATSAVDDFAQSQNGLSGAVCCFHCGLPVPESGNWNAKIKGLMRPMCCPGCQAVAQSIVDSGFGDYYQTRIGYSATADQQTLIPPELALYDSEENSEQFGGQKEFGEATFSIEGIRCAACVWLIERRMARLPGMRSADMNVATGRLSACWNRAVCKPSDILRTLREIGYVAYPFDAARYGEQLELARKKLFRRMFIAGLSMMQVMMYALPIYMASDGTMDADMTNLMRWAGLLLTLPAIGYAAQPFFIGAWINLKSHMLGMDVPVALGISAAFIGSVLATFKGQGDVYFDSITMFIFLLLCSRYLELGARRKAASALDNLQHALPASALRMAGYPAFRETELVAAGKLVSGDVILVKPGEANAADGVILEGDTAFDLSMLTGESRAQRMTIGANVPGGAVNVTQPVVLRVTQSTGESTLSVLMSLIERAGQGKPKIALWADRAAAWFVAVLLLFSVSVFIVWHFLDPSRAWPIAIAVLVVSCPCALSLATPTVLAAATNRLLRQGILVVQPHVLETLNQATHIIFDKTGTLTVGKPVLSHIEALAAIPSKQCLRVAASLAASSKHPLSEALVTAAAEDDSISGMDLFCGDIRHIAGQGLDGLMDGKRYRIGSLAFVQELAGSDFAPPNVPGFVSIYLGTENVLLARFDLADSLRADASWIVRYFQDKGKTVILLSGDHQSVTQHVADELGITTALGQNLPDQKLNYVQNLQRDGGIVAMVGDGINDAAVLSAADVSFAMGSGTALAQIHADCVLLSGQLTSLAVLNDTASKTLTVIRQNLFWATLYNLIAIPAAALGLLNPWMSGVGMSLSSVVVVLNALRLQRLPRHINYPTPTTSPKGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0L7</accession>
    <name>A0A2S9H0L7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Trypsin-like peptidase domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1908</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93521">
        <property type="protein sequence ID" value="PRC93521"/>
        <property type="gene ID" value="S2091_1908"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="SSF50494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="268" mass="28475" checksum="852D2C320CB00C79" modified="2018-07-18" version="1">MNLTNSTPRISLARRAKLLVLYCLFLTLAKPLYASDFSDVIKAIKPSVVAIGSVQKTRSPAISFKGTGFAVGDGLTIITNAHVINTPLNAAEQETLGVLIERKGDTPEFRTAVITAVDEEHDLARLTIGGTPLPALTLGDISQVDEGQSIAFTGFPLGIVLGFQHVTHQGIISALTPIVRPALTALQLNPKMAAQLRRTPFIVLQLDATAYPGNSGSPLFDPQNGKVLGVINMVFVKGLKEAAITNPSGISYAIPVNYVSDILKLKVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0Q5</accession>
    <name>A0A2S9H0Q5_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">LysM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1833</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93446">
        <property type="protein sequence ID" value="PRC93446"/>
        <property type="gene ID" value="S2091_1833"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045361">
        <property type="entry name" value="CIS_tube_prot_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19266">
        <property type="entry name" value="CIS_tube"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51782">
        <property type="entry name" value="LYSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LysM" evidence="1">
        <location>
            <begin position="160"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="211" mass="23159" checksum="CC51E203838B6439" modified="2018-07-18" version="1">MAKNGTISVDSSRPVFQALINPSGYGHDFSIKYAKTQALGQAGNEAKFNASQPEKLSLKELVLDGTGVVPGTTKTVKQQVESLRSAVYTYVGTKHEAPIVQVVWGSLIFYGRVEGLKFDYTLFKPNGEPLRAKISLNFIEYTSTAEIVKEEANGSPDLTHLVIVQAGDTLPLLCDRIYRDSGYYMEVARVNGLSSFRHLQPGMSLRFPPLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0S6</accession>
    <name>A0A2S9H0S6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1568</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93567">
        <property type="protein sequence ID" value="PRC93567"/>
        <property type="gene ID" value="S2091_1568"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015528953" evidence="1">
        <location>
            <begin position="23"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="151" mass="16716" checksum="41886355227120FC" modified="2018-07-18" version="1">MKLKQPLFALLFAALLPLAAHADLPGKHPAYLHALSDLRDARWKLEHRPGDAAVSGQEDVAITEVDKAIGEIKKAAIDDGKNLNDHPHEDAAMDHPGRLHHALELLKKAESDVSGEEDNPETRELKHRVMDHIHAAIHATEHAIHDVETHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0U1</accession>
    <name>A0A2S9H0U1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1605</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93604">
        <property type="protein sequence ID" value="PRC93604"/>
        <property type="gene ID" value="S2091_1605"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="80" mass="9018" checksum="9A85DAF087A071FB" modified="2018-07-18" version="1">MVKEVQMSIKMESELRDQFMAVAAGRHRPAAQIIRDLMRLYIAESAVPNALTAETIRKSDQNEDVFHASSAQDLFKKLGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0Z1</accession>
    <name>A0A2S9H0Z1_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">VOC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1628</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93627">
        <property type="protein sequence ID" value="PRC93627"/>
        <property type="gene ID" value="S2091_1628"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="12"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="120" mass="13897" checksum="130DC612B7D1438F" modified="2018-07-18" version="1">METTLTHTKLPRLHQACPVLASLDFERSYQWYSQLGFHRAHDHPLVLKRDDVTLHFRACKESHIAATTSCRIAVHNIADWYEFCLNLQIVHPKAPLTTQPWGLQEFAVLDVDNNLLVFFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H130</accession>
    <name>A0A2S9H130_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SURF1-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_1696</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the SURF1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93695">
        <property type="protein sequence ID" value="PRC93695"/>
        <property type="gene ID" value="S2091_1696"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd06662">
        <property type="entry name" value="SURF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002994">
        <property type="entry name" value="Surf1/Shy1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045214">
        <property type="entry name" value="Surf1/Surf4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23427">
        <property type="entry name" value="PTHR23427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02104">
        <property type="entry name" value="SURF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50895">
        <property type="entry name" value="SURF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="211"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC93695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="234" mass="26159" checksum="9C768BDFAF7E339B" modified="2018-07-18" version="1">MLTFRFRLVPFIATLLLVALGCSLSYWQTQRAHQKEAIEAKLLARENTPAIPLPSSQDINQIEYTRVVLTGEFVKDWPVYLDNRPMNGMAGIVVMMPFKLQGQSSYVLIARGWLPRNSLDRAAIKKYQTPSGLIQIEGTLKANSGHVLQLGQSATLQPNALIQNLEVNAFIAASKLPTYPFIVEQTKGPEDGLLRDWPRASMGSERHRGYAFQWLALAGMALLFYLVTGLKRGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1C7</accession>
    <name>A0A2S9H1C7_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 13">Adenine DNA glycosylase</fullName>
            <ecNumber evidence="4 13">3.2.2.31</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">S2091_1377</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>Hydrolyzes free adenine bases from 7,8-dihydro-8-oxoguanine:adenine mismatched double-stranded DNA, leaving an apurinic site.</text>
            <dbReference type="EC" id="3.2.2.31"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="13">Binds 1 [4Fe-4S] cluster.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the Nth/MutY family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.2.31" evidence="4 13"/>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93768">
        <property type="protein sequence ID" value="PRC93768"/>
        <property type="gene ID" value="S2091_1377"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000701">
        <property type="term" value="F:purine-specific mismatch base pair DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03431">
        <property type="entry name" value="DNA_Glycosylase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00056">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1670.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005760">
        <property type="entry name" value="A/G_AdeGlyc_MutY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011257">
        <property type="entry name" value="DNA_glycosylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004036">
        <property type="entry name" value="Endonuclease-III-like_CS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004035">
        <property type="entry name" value="Endouclease-III_FeS-bd_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003265">
        <property type="entry name" value="HhH-GPD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023170">
        <property type="entry name" value="HhH_base_excis_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000445">
        <property type="entry name" value="HhH_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044298">
        <property type="entry name" value="MIG/MutY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029119">
        <property type="entry name" value="MutY_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42944">
        <property type="entry name" value="PTHR42944"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00633">
        <property type="entry name" value="HHH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00730">
        <property type="entry name" value="HhH-GPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14815">
        <property type="entry name" value="NUDIX_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00478">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48150">
        <property type="entry name" value="SSF48150"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01084">
        <property type="entry name" value="mutY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00764">
        <property type="entry name" value="ENDONUCLEASE_III_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01155">
        <property type="entry name" value="ENDONUCLEASE_III_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="7 13" id="KW-0227">DNA damage</keyword>
    <keyword evidence="11" id="KW-0234">DNA repair</keyword>
    <keyword evidence="12 13" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9 13" id="KW-0408">Iron</keyword>
    <keyword evidence="10" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ENDO3c" evidence="15">
        <location>
            <begin position="57"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU365096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM00478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="PRC93768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="381" mass="42609" checksum="7762B43D80DD1B8A" modified="2018-07-18" version="1">MKRVIESSSGSGNGNDRNYADNSFSQDVVQWQKLHGRHSLPWQQSRDAYRVWLSEIMLQQTQVAAVIPYYQRFLTSFPDVVSLANASSEQVMAHWSGLGYYTRARNLHACAKRVTQEYAGVFPHQPELLAELPGIGRSTAAAIAAFSYGARAAILDGNVKRVFTRVFGIDGIPAVRAVEDDLWQRAQALMPEGKEQIQAYTQGLMDLGATLCTRSKPRCEACPLQARCVALATNRVAELPAKKPKKAIPTKQIMMLLLLNKQQVLLEKRPESGIWGGLYSLPELAYEAGMPMQQLSQYFEAAVRPFGDLDMLVPLAKITHVFSHFKLEISPYQCSLKRRISAIAEDTHVWYPIEQCDNAPLPAPIKKLLMQVSGEFNEIKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1D3</accession>
    <name>A0A2S9H1D3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Antimicrobial peptide resistance and lipid A acylation protein PagP</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_1404</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the lipid A palmitoyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93795">
        <property type="protein sequence ID" value="PRC93795"/>
        <property type="gene ID" value="S2091_1404"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011250">
        <property type="entry name" value="OMP/PagP_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009746">
        <property type="entry name" value="Peptid-resist/lipidA_acyl_PagP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07017">
        <property type="entry name" value="PagP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56925">
        <property type="entry name" value="SSF56925"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015777254" evidence="3">
        <location>
            <begin position="24"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC93795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="205" mass="22595" checksum="6DFA96F8DB2810E1" modified="2018-07-18" version="1">MKFFTLRHFSAVLFLSFACSAYAQTSDTAPAPANTDTTTEQPGWFKKTYDDAVNTTENLYDNGRLSTILSGYAHHGRGTYTAERIDELNEKTWGLGMSKELRDSKDNEESLQIVIMADSHYKPQITAGYSYQWMKSLGGNWEAGIGYTAGLISRTDILQGVPFPGILPLFSIGTRDTKLVASYIPKLSGTGNGDVLFLALRVSLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1L9</accession>
    <name>A0A2S9H1L9_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Fido domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_1493</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93884">
        <property type="protein sequence ID" value="PRC93884"/>
        <property type="gene ID" value="S2091_1493"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025758">
        <property type="entry name" value="Fic/DOC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003812">
        <property type="entry name" value="Fido"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036597">
        <property type="entry name" value="Fido-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040198">
        <property type="entry name" value="Fido_containing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026287">
        <property type="entry name" value="SoFic-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13504">
        <property type="entry name" value="PTHR13504"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02661">
        <property type="entry name" value="Fic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13784">
        <property type="entry name" value="Fic_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038925">
        <property type="entry name" value="AMP-prot_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140931">
        <property type="entry name" value="SSF140931"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51459">
        <property type="entry name" value="FIDO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="228"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="domain" description="Fido" evidence="5">
        <location>
            <begin position="130"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="216"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="82"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="216"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="220"/>
            <end position="227"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="221"/>
            <end position="227"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="258"/>
            <end position="259"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="258"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR038925-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR640198-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR640198-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC93884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="388" mass="42828" checksum="B3250C3B0DC31D5C" modified="2018-07-18" version="1">MHRGKTGTYTSTIAGGVACQAFVPMPLPPQPALEISGKLQTRLNNALIALGRLDAISTLLPDAKLFLYSYVRKEAVMSSQIEGTQSSLSDLMLYEMEGQPGVPMDDVREVSCYVNALTLGVERIRQGHPISFRLLTEIHQVLMTSGRGIQRGPGEFRRNQVWIGGHRADEATFVPPPANQIADCWASLEQFINDLPEITPPVIKAALVHVQFETIHPFMDGNGRIGRLLIPLILVEAGILNEPLLYLSLFFKQYRDTYYRLLQEVRMTGDWEAWLLFFVDAIAATANQAVSTAQQLMHLLAADKLRLAQTGRLSGSATQVLDALFAHPISNISKLTDATGLTAATIGKALDMMQEQLGIVHELTGQKRNRVYAYSAYIAILNQDTTQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1S1</accession>
    <name>A0A2S9H1S1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Flagellar biosynthesis/type III secretory pathway protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_1502</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93893">
        <property type="protein sequence ID" value="PRC93893"/>
        <property type="gene ID" value="S2091_1502"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018035">
        <property type="entry name" value="Flagellar_FliH/T3SS_HrpE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02108">
        <property type="entry name" value="FliH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0966">Cell projection</keyword>
    <keyword evidence="4" id="KW-0969">Cilium</keyword>
    <keyword evidence="4" id="KW-0282">Flagellum</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="FliH" evidence="3">
        <location>
            <begin position="107"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC93893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="254" mass="28019" checksum="5A2082CA903AFF19" modified="2018-07-18" version="1">MVSIIRSPAISEHKHKLSVRRNRSPEKHETDRNSLPLATQQNHKTTESIQKEERANELASALEQTRLSIMEQFKEEAAAARELGRQRGLREGRVTGIEESKQSFANEIARIKSIAEKLPQALESGIHGMEDALVSIAFEAVCKILGTSAVTREGIKTIVQQAAANTLSNEQLVVRLQPNDFKLLQDAGGFSASLKTGQTVKWVADKKIVMGGCMIETATGELDARLETQVQALRTVLVKVRDERRATINGLLLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1T5</accession>
    <name>A0A2S9H1T5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1124</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC93951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93951">
        <property type="protein sequence ID" value="PRC93951"/>
        <property type="gene ID" value="S2091_1124"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="2">
        <location>
            <begin position="1"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="176"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="386" mass="43633" checksum="E96EC4FF19ADDADA" modified="2018-07-18" version="1">MGGVEQVIHQIATGASKQGVHTEVLALTTNRMPRTIEMNGYKVNRARMNFQIASTGFSASAFLRFSQLAKKADIIHYHFPWPFMDVVHFATRVKKPSVVTYHSDIIRQKYLLKLYRPLKRKFLASVDRIVTTSPNYLKTSNVLEKFSDKVSIIPIGLDKATYPQPSLEKLQYWRTKLGPKFFLFVGVIRYYKGLHILLEAMQGVDYPIVIVGAGPIEDELKALKKQLGLRNIHFLGQLPDEDKVALFTLCYGVVFPSHLRSEAFGVSLLEGAMHGKPMISSEIGTGTTFINIADLTGLVVPPSDPTALQQAMRYLWEHPTEAAEMGQRAAERYWQHFTADQMAQSYVDLYGELLHSRENLHRHYVDQTLARCGDLSALPHRASDNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H204</accession>
    <name>A0A2S9H204_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1505</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93896">
        <property type="protein sequence ID" value="PRC93896"/>
        <property type="gene ID" value="S2091_1505"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="35" mass="3644" checksum="9EAC276650ED923E" modified="2018-07-18" version="1">MKEFCKKAIAYVKEPVTGGAVAVNGFEGAVNLTSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H216</accession>
    <name>A0A2S9H216_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 13">Membrane protein insertase YidC</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12 13">Foldase YidC</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11 13">Membrane integrase YidC</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Membrane protein YidC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">yidC</name>
        <name evidence="15" type="ORF">S2091_1204</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="13">Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="13">Cell membrane</location>
            <topology evidence="13">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94031">
        <property type="protein sequence ID" value="PRC94031"/>
        <property type="gene ID" value="S2091_1204"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032977">
        <property type="term" value="F:membrane insertase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01810">
        <property type="entry name" value="YidC_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019998">
        <property type="entry name" value="Membr_insert_YidC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028055">
        <property type="entry name" value="Membr_insert_YidC/Oxa1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028053">
        <property type="entry name" value="Membr_insert_YidC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001708">
        <property type="entry name" value="YidC/ALB3/OXA1/COX18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038210">
        <property type="entry name" value="YidC_periplasmic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038221">
        <property type="entry name" value="YidC_periplasmic_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12428">
        <property type="entry name" value="PTHR12428"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02096">
        <property type="entry name" value="60KD_IMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14849">
        <property type="entry name" value="YidC_periplas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00701">
        <property type="entry name" value="60KDINNERMP"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01900">
        <property type="entry name" value="YIDCPROTEIN"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03593">
        <property type="entry name" value="yidC_nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03592">
        <property type="entry name" value="yidC_oxa1_cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 13" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10 13" id="KW-0143">Chaperone</keyword>
    <keyword evidence="9 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 13" id="KW-0653">Protein transport</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 13" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="376"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="445"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="486"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="515"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="domain" description="YidC_periplas" evidence="14">
        <location>
            <begin position="125"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00033245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00033342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF14849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="PRC94031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="560" mass="62283" checksum="20D82B643B7D7F7D" modified="2018-07-18" version="1">MNKRIVLWIVFLMSLLLLWENWQRFNGNPSMFFASPTQVVKKDALQTDPANPTVAAVDGSTPGVTDATAVPLHGEVITIVTDVFKVEIDTLGGELSHLELLKQKEGADTSFGSGWKSLIMPNATHTAESNVVLFDRSEKRTYLAQSGLLGNYPNHKSLFVAKPGLRTLDAAGQVQLVLESEQNGVKLVKTYTFKKGSYSIDLSHQVVNDTAAPITPSVYMQLVRDGGKLEGESRFYSTFTGPAVFTEEEKFQKLTFDKIEKHSETHALKADNGWIAMIQHYFVSGIIPQDKVQREIFTKKVDTNLYAVGNIMTMGTLAPGASETLSAQIYSGPLVTSILDHVAPGFNLVKDYGWTTIVAKPVFWLMDEIHNVLGNWGWTIIVLTIFIKLAFFPLSAASFRSMGKMKLLTPKMTAIRERHKEDPQKMNQAMMELYKTEKVNPLGGCLPILIQTPVFMALYSVVLASVELRNAPWLGWIHDLSTPDPFLILPILMAVSMFIQTKLNPAPADPMQAKMMAIMPLVFSVMFFFFPSGLVLYWVINNVLSIAQQWVITKNIAAAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H253</accession>
    <name>A0A2S9H253_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HTH cro/C1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1213</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94040">
        <property type="protein sequence ID" value="PRC94040"/>
        <property type="gene ID" value="S2091_1213"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="55"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="144" mass="16253" checksum="3EF652399DECE2A7" modified="2018-07-18" version="1">MGHYCISQNVRMPTIEEKVSFSKRLDASLRRSPEPVKGATELALRFNLRYVGDAVSAQTAHKWLTGRAIPTHDKLATIAKWLNVDEHWLHYGASPAGTNVRKHAAPAMNDVITPEVITLAQRILLLPPHQRYLIEDLIAQLRQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2Q8</accession>
    <name>A0A2S9H2Q8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">GGDEF: diguanylate cyclase (GGDEF) domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_0885</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94264">
        <property type="protein sequence ID" value="PRC94264"/>
        <property type="gene ID" value="S2091_0885"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="29"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="329"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="3">
        <location>
            <begin position="349"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="4">
        <location>
            <begin position="451"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="393"/>
            <end position="423"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC94264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="592" mass="65225" checksum="0FFF154F219BFC10" modified="2018-07-18" version="1">MKIFQLLLAPAVALMGRLRYPYKFATIGLLGVVAIVYLFLVLTSHLQASMDTGHREQLGVMLDKPLLSLVQTIQQHRSLSVALLGGVKSLTEKRINKATEIHEVITAVDQVVVAHGAELNVLTDWQLAKAHWENIQANGLQMSARTNRDTHTAVIKELLSMVARIGDNSFLVLDPNANSYYLMDAATNKLPAALEIVSQLRAHGAEVLATKSLDETGRVEFVGEVAVLRSKLEELDAALQRVAASNPKVAPRINQFLPPFHASINDVLKIVTDDILSARFTADTEQFIEKTTTAIDRGYAQSQELLLPVLHELLETRIKQMQHQYFESAILAGPAFLMLFIYLATGAYLAVMSSIESLREGADRMAEGDLITPIALATKDELRHVAVSFNHMSEQLARRIKDAQQHSTELEALNLMLKSLSATDGLTGISNRRHFDEALATEWQRAARLKQPITLGMLDVDWFKKYNDQYGHLLGDECLQRIAKVLANSIARTGDVVARYGGEEFAFIALNCDSKQSQLIANNIIKAVEALWLPHQMSEFGHVTVSIGVASIIPKAGDAAHTLLKAADDALYTAKESGRNRIVIASFDSTPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2T2</accession>
    <name>A0A2S9H2T2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">PAS domain S-box protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0916</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94295">
        <property type="protein sequence ID" value="PRC94295"/>
        <property type="gene ID" value="S2091_0916"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011712">
        <property type="entry name" value="Sig_transdc_His_kin_sub3_dim/P"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07730">
        <property type="entry name" value="HisKA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13188">
        <property type="entry name" value="PAS_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PAS" evidence="2">
        <location>
            <begin position="29"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="1">
        <location>
            <begin position="282"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="373" mass="41780" checksum="D033E37421EBADFA" modified="2018-07-18" version="1">MQISSNSPKKRIAAINTINASSLKALRLSESRYRRLFETAQDGILLLNADTAQIEDVNPYLINMLGYSHAVFLGKKLWEVGSFADVAESKNMFAELQTTGYVRYEDLPLKTKSGELIEVEFVSNTYECEDIKVIQCNIRNISQRKQVERELIESKAHLHQLSIFLQRAREEDRAHFSRELHDELGQNLTVLRIDFNGLANQLATSDPAIAARLDAIDQVIIRTVDATRLICEELRPGMLDDLGFEAAITSYARSFTKRFGVPCDLLLDREDYGLDKYLSTAIFRIVQEALTNIARHAQASHAMVALQDCDNGLLLTIADDGIGLPTELTDERKTFGILGMKERVNMLGGRIAIDSAPGRGTHIEVNIPRNDSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H300</accession>
    <name>A0A2S9H300_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Prepilin-type N-terminal cleavage/methylation domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0980</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94359">
        <property type="protein sequence ID" value="PRC94359"/>
        <property type="gene ID" value="S2091_0980"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="206" mass="22831" checksum="EA59C5A0898B7717" modified="2018-07-18" version="1">MVYKLKPFRHLKKGFTLVELLVAISILAVIAVIGWRGLDGIVRARVAISADMEFTRRMQLTFAQLQRDCAQTASIDALSGRQALQATDGQLTLRRTVEVDNQPMWFEVVTYRIANGNLTRSESPPTRDMGVLDQMWNDALQNADHGAAVTLQSNMASMTMRVWQDDGWIPAMLTDLSGPMPSALEVEMKISGHQTAIVKALLMGTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H369</accession>
    <name>A0A2S9H369_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ATP-grasp domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1004</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94383">
        <property type="protein sequence ID" value="PRC94383"/>
        <property type="gene ID" value="S2091_1004"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-grasp" evidence="2">
        <location>
            <begin position="118"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="408" mass="44767" checksum="E01A53172C0ACFF5" modified="2018-07-18" version="1">MNQHLLILARGEARTYRGVDGRSLLDGLPFEVTLFADRGNGPDLRALEGEHEIEVVRWSDEPAIIQRAIELHTGVPFTAVTTFDEQIVGLAAKIRDALGLPGLTPEAAELFRDKMRMKTVLDQAKVRTPNACHASDRAEVEALLTKYGKLVVKPVNGMGARDVVFIDNAAQLDAWYAEGKNTAEFEAEEFIDGVLYHVNALVRDGVPLLTASAIYVPGMGNIDFAAGTPFVSAMVIEPVLKGRLEDFSNLVIAALGMRDGVTHLECFVTPTGEIVFCEVGARPGGGGIVWMIEQHCGINYNHALMMLEAGHGKQLQIPAQQQGLVGLMGFRSAQSAFIQRAAEQSDFSEDWIHVRQIDIGQGVFKPAAAHCTDFLGLFVFSSNDMDHFEQRRRNLSERFYNALEMQAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H372</accession>
    <name>A0A2S9H372_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="12">ABC-type multidrug transport system ATPase and permease component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">S2091_1053</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94432">
        <property type="protein sequence ID" value="PRC94432"/>
        <property type="gene ID" value="S2091_1053"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="PTHR24221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="SSF90123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-1278">Translocase</keyword>
    <keyword evidence="2 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="33"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="111"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="135"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="224"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="257"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="11">
        <location>
            <begin position="1"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="312"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="346"/>
            <end position="353"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PRC94432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="557" mass="60717" checksum="C78B3280810B441F" modified="2018-07-18" version="1">MLFTVGTLTVWIPRRVGHLVDEMVAGRLTDTLILQQLGILLLMGVAIYFLRVGWRMQLFVASYQLGVHLRTELYKRLCLQGPDFFQQQRTGDLMALGTNDADAIELAAGEAMLAGFDGTLTLVMVLAMMFLGVDWRLALIALLPFPFMALAFKRITQQVHDASHEALTCFSQLNGQVQESLAGVRTVRALGLESRNASQFAVLAEQAADASLRAQRWEAGYEPAVGLALTTAGFLTLSLGGYLVWHAQMSIGSLTSFTMYLGQLIWPMFAAGWVLSLVERGRAAWRRLEPVLGLPLSIEDAGTITTPPHGSVQFSDVHFAYSEQAQAALQGVSLTLKQGTTVGLVGPTGSGKSTLIRLLLRQYAAQQGSINWGEHQLSDYRLENLRGHISWVAQEPFLFSASVAANIALGKPDATQVEIEQAAQLAAVHDDILRFPLGYDTPVGERGVTLSGGQRQRVAIARALLTNSPLLLLDDALSAVDTGTQTSILQHLRGARVGRSVLLVSHRLSAVADADNIVVLRHGKITEQGTHVSLLEQDGWYASQWRYQQLEAALDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H375</accession>
    <name>A0A2S9H375_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0937</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94316">
        <property type="protein sequence ID" value="PRC94316"/>
        <property type="gene ID" value="S2091_0937"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="187" mass="21996" checksum="2E555070FB8BAB22" modified="2018-07-18" version="1">MTMASCEYADEVPCKSNNYAFFDDVCANELINAVTVDQIINLSKFCTSIPLDFIENDPTDVLKFNKLLTRAKDKVGVYHLWVENSRCSDHKIYSMLCVYVGKGDILDRVKEHTKEKYENQGLLHLSFYECENRIAKYLEQLFLDIYDFPMNHKENKNSKNEKLYARWSSDRYNIGTEMEFLSDRYSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H386</accession>
    <name>A0A2S9H386_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Zinc carboxypeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1059</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94438">
        <property type="protein sequence ID" value="PRC94438"/>
        <property type="gene ID" value="S2091_1059"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004181">
        <property type="term" value="F:metallocarboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000834">
        <property type="entry name" value="Peptidase_M14"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00246">
        <property type="entry name" value="Peptidase_M14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00631">
        <property type="entry name" value="Zn_pept"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015691025" evidence="1">
        <location>
            <begin position="21"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M14" evidence="2">
        <location>
            <begin position="33"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="296" mass="32557" checksum="3A0228E109D828A1" modified="2018-07-18" version="1">MRNGYVGVLVGLMFSLPVLAGSSTPPKNVKNPINQWCTPLVNRLPKVTMAQCQNSALQASGSVSKKGFPLLIKDVPARLVNNTLPIKSPIKVLLIGGIHGDEKTASAIVFQWLDKLNNTAGNEFHWKIAPVVNPDGLLAAKPTRVNANGVDLNRNFPTPNWNKEALQYWRTKTSSDPRRFPGKAALSEPESRWIFNQMEQFQPDVIISVHAPFGVLDFDGSGTPPSKFGRLLFNRVGVYPGSLGNYGGLHKEIPVVTIELTNSSQMPSDAEIARIWQDMLDWVKLNIPSQAKLAEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3D5</accession>
    <name>A0A2S9H3D5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0491</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94488">
        <property type="protein sequence ID" value="PRC94488"/>
        <property type="gene ID" value="S2091_0491"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006148">
        <property type="entry name" value="Glc/Gal-6P_isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039104">
        <property type="entry name" value="PGLS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11054">
        <property type="entry name" value="PTHR11054"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01182">
        <property type="entry name" value="Glucosamine_iso"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glucosamine_iso" evidence="1">
        <location>
            <begin position="11"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="224" mass="24300" checksum="89635A9015D47CDB" modified="2018-07-18" version="1">MLRINEYSDFASLSHELANKWLALVTSTPANQPCSFALAGGSTPAPLYRQFDSLFAAAKPRSIQLIATDERWVPDADPQSNEGLFRNCFSESAALWKLVSLKNELSDPASAAPYIHTRLQEQCDHTFSAVILGMGTDGHIASLFPDAPQLLIADDAVNCVAALHPQTQQARMSLSFSRLLATQSIWLVITGAEKRAVLENSSAPSPVNALLAAARCDVEVFWCP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3G3</accession>
    <name>A0A2S9H3G3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0527</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94524">
        <property type="protein sequence ID" value="PRC94524"/>
        <property type="gene ID" value="S2091_0527"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="24"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="140"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="161" mass="17766" checksum="68D826B4D2B24061" modified="2018-07-18" version="1">MNISITAERIPQHKGNLSRNTVRGIAYLTFFCSMALLSWPAAAQHKMTEAAERYQIEHANCLNGRSNEDKETCLKEANAALMQAKQGRLDDAGAQYQKNAELRCQVFESEDRQACERRMRGEGTVSGSVANGGIFRKLVIPEPEPKPLITPESGGATDKLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3S1</accession>
    <name>A0A2S9H3S1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0638</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94635">
        <property type="protein sequence ID" value="PRC94635"/>
        <property type="gene ID" value="S2091_0638"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="308" mass="34366" checksum="B879BB3F54BD41B3" modified="2018-07-18" version="1">MKNIIYYIKSKIGYFVLFIFILMSACLYYFLKEPASNSPLESKLHSSEAWKQSPFEKNRSELNEQPTVKVFISLPDQIDRLIATRNPANALKAYWLVTDCIHFQQWGNLPVFAFPVFREMTVTEKSDEVKLCSGLTERLKTASLENLSYAVKNGVSGAAIAFLQAGPFGDKSALESRPNDPLIIEWKKQAIAQLTEIANNGDYMSVLVLANEYDSSNGVVENNPSLAFTYAIATRQFDDRFGIPSQFNDERLARLQSGLSQDEINTATSSATTISANWLKNVREQGEILSNSVAAPAISPLNLLVESR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H417</accession>
    <name>A0A2S9H417_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">MdcA: malonate decarboxylase, alpha subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0721</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94718">
        <property type="protein sequence ID" value="PRC94718"/>
        <property type="gene ID" value="S2091_0721"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005777">
        <property type="entry name" value="MadA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16957">
        <property type="entry name" value="Mal_decarbox_Al"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01110">
        <property type="entry name" value="mdcA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="558" mass="61093" checksum="49AA55DF1F09C329" modified="2018-07-18" version="1">MMGNIAQTTRPLSPQWSKRRAEKLRRISLAAHLADGPVLKTEDIVAALSVLISSNDRVVLEGNNQKQADFLSRALVQVDPGKINNLHLIMPSVSRTEHLDLFERGIASKLDFAYAGAQSLRIAQFLQDGILEIGAIHTYVELYARLYVDLTPNVVLVAGFKADRQGNLYTGSSTEDTPALVEAAAFRDGIVIAQVNEIVDDPADLPRVDIPGSWIDFVVQADKPFFLEPLFTRDPRLIKPVHVLMAMMAIRGIYEKHQVQSLNHGIGFNTAAIELILPTYGEQLGLKGKICKNWTLNPHPTLIPAIESGWVESVHCFGGELGMEKYVAARPDVFFTGRDGSMRSNRAYCQLAGQYAVDLFIGSTLQMDGLANSSTVTHGRLTGFGGAPNMGHNPGGRRHASPAWLDLIETEDPMARGKKLVVQMVETFQNGAQPTIVETLDAVQVGKESGMPIAPVMIYGDDVTHVLTEEGIAYLYKARSLEERKAMVAAVAGVTPIGLRHDPTTTAKLRQDGLIAFPQDMGVNRHEATRSLLAAKSVAELVTWSDGLYEPPVKFRSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H419</accession>
    <name>A0A2S9H419_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative metal-dependent hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0704</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94701">
        <property type="protein sequence ID" value="PRC94701"/>
        <property type="gene ID" value="S2091_0704"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002725">
        <property type="entry name" value="YgjP-like_metallopeptidase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01863">
        <property type="entry name" value="DUF45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF45" evidence="1">
        <location>
            <begin position="40"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="261" mass="30301" checksum="6EFBE25EA7D6C0F1" modified="2018-07-18" version="1">MTVSIMRNLEPTGVKKMSITYGDEKISFDCIKGSQTSARVLIQVHPDCRVVVSAPDDADSQAVLDAVKKRSRWIYEQLRDFRKQLAYITPRKYVSGESHYYLGKQYVLKVIEAPEMEQCVKLLRGKLEVTVHQKSQIKIENMLSDWYKERAKDVFIKRLDAMLEQALWVKERPSIRVLTMKTQWGSCSPNGRLTLNPHLIKAPRQCIDYVILHELCHIAEHNHGKRFYRLMKQVMPNWEKTKKVLDGMANLILADVSQLDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H476</accession>
    <name>A0A2S9H476_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PilM: type IV pilus assembly protein PilM</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0782</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94779">
        <property type="protein sequence ID" value="PRC94779"/>
        <property type="gene ID" value="S2091_0782"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005883">
        <property type="entry name" value="PilM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003494">
        <property type="entry name" value="SHS2_FtsA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11104">
        <property type="entry name" value="PilM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF019169">
        <property type="entry name" value="PilM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00842">
        <property type="entry name" value="FtsA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01175">
        <property type="entry name" value="pilM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FtsA" evidence="1">
        <location>
            <begin position="16"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="359" mass="39105" checksum="3ED1AE7D0DEB86CE" modified="2018-07-18" version="1">MSDALASLTGKKNTPLIGIDISSTSIKLVELSEGSNKELRLERYASEPLPRGAMSDGNIENIDQVSEAIRRVVMKSGTKIKKVSLGMPSAAVITKKIILSGGASEEQLEMQVESEASQYIPFALDEVRLDFCVIGPAPNSPEDVEVMLAASRKEKIEDRVAVAEAAGLKSMVMDIESYAARSAISRVIAQSDNGGKDKIIALFQIGAKITHISVLLNDQTVYEREQTFGGNQLTQEIVRSYGLAFEEAELKKKNGELPEGYDEDVLNPFLESAALEVTRAIQFFFTSTPYTRIDQIYLAGGCVVLPGLLDMIASRTKISTAVISPFKGMELSPNIKEKQLRSEAPSFLVACGLAMRRFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H490</accession>
    <name>A0A2S9H490_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phage integrase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0805</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94802">
        <property type="protein sequence ID" value="PRC94802"/>
        <property type="gene ID" value="S2091_0805"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002104">
        <property type="entry name" value="Integrase_catalytic"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00589">
        <property type="entry name" value="Phage_integrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51898">
        <property type="entry name" value="TYR_RECOMBINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyr recombinase" evidence="2">
        <location>
            <begin position="186"/>
            <end position="409"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="424" mass="48687" checksum="2AF92594CDAAFF02" modified="2018-07-18" version="1">MPSCNCKIKSFVMKNGERYCLLVSKASGLPYYYPNLFLITQVRNRSLSTAAMESTLASLNVLMAFNEKSNVDIEVRFLKRLFLQPNEMDAIRDYCQLNFSGPRDSAASKNVLQLPNQNRQRKKRVIRTTDRASTYNRLTHIAHYSKWLAETLLSTNTDKHTTLEIEKMYSGLKARRPPKKCCNQAESEEGLSREQIDVLLEVVQPGSERNPFHDPAIQVRNQVIILLLLYLGIRGGELLNIRVRDISFSNNQIVIARRADDKSDPRIDQPLVKTLDRRIPMKPTLVSEIHNYILHHRNKVPRARKHDYLFITHKAGPTQGQPMSRSAYEKLIALIAKSSPELSILRGHGLRHTWNDSFSRLMDEMENPPSPEMQEQQRSYLQGWKSGSGSAAIYTKRHIKIRALEAGLQLQERMSIIPKNLKND</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H491</accession>
    <name>A0A2S9H491_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">YfiA: ribosomal subunit interface protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0793</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94790">
        <property type="protein sequence ID" value="PRC94790"/>
        <property type="gene ID" value="S2091_0793"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044238">
        <property type="term" value="P:primary metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00552">
        <property type="entry name" value="RaiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036567">
        <property type="entry name" value="RHF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003489">
        <property type="entry name" value="RHF/RaiA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02482">
        <property type="entry name" value="Ribosomal_S30AE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69754">
        <property type="entry name" value="SSF69754"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00741">
        <property type="entry name" value="yfiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0810">Translation regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="129" mass="14925" checksum="604F04507211EB6E" modified="2018-07-18" version="1">MNITISGHHLEVTPAIREHIQSKLERIMRHFDQVIDITVTITVDKLKEKDKRHKADINLHVPGKDIHVESMAQDLYAAIDLLMDKLDRQVIKHKDKIQDHKHDPVKHMPIHLTEHAELDENAYNSLASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4H9</accession>
    <name>A0A2S9H4H9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alpha/beta hydrolase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0063</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94868">
        <property type="protein sequence ID" value="PRC94868"/>
        <property type="gene ID" value="S2091_0063"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000383">
        <property type="entry name" value="Xaa-Pro-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02129">
        <property type="entry name" value="Peptidase_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015629003" evidence="1">
        <location>
            <begin position="23"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S15" evidence="2">
        <location>
            <begin position="50"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="467" mass="51394" checksum="2EEA55D209C0A586" modified="2018-07-18" version="1">MRLVFFSYFITSILLNTQPAFAESSDALLMPNAPMNEQVLSIPGDPDRPVMLQVTVFTPNGPGPFPLAILNHGASGDTPPASQPRNRTTYAADYFLSRGYAVALPMMRGYAGSGGKVEVNWCDFLSMGLRNARDVRAVVSYMEKQPNIDANRVVMAGQSFGGWNTLAFGALQYPNVKGLINFSGGLVASNCATDLKLSQAVSYFGEHSRVPSLWFYGDNDKLFPVETWRKMLERYTKNGGNAELVAYGKFMENSHLMLSFPESFPIWVPKLDAFLAKIGLPNQLVYPEYMPTAFPPPSHFAAIDDVNAIPYVNDKGRELYQRFLAKPLPRVFALASNGSASMQNGGFDPIKITINQCQQHAPSCRVYAVDNEVVWVRPTSAPPTTHFATLMDQTALPYVNEQGREGYVKWLALKKPRAFVIAPNGAWSGTSRGDDPLAQALSACNKMTSGCQLYAVDDAIVWPELVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4K3</accession>
    <name>A0A2S9H4K3_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7">Chaperone protein DnaK</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">HSP70</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Heat shock 70 kDa protein</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Heat shock protein 70</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">dnaK</name>
        <name evidence="10" type="ORF">S2091_0110</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Acts as a chaperone.</text>
    </comment>
    <comment type="induction">
        <text evidence="7">By stress conditions e.g. heat shock.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7 8">Belongs to the heat shock protein 70 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94915">
        <property type="protein sequence ID" value="PRC94915"/>
        <property type="gene ID" value="S2091_0110"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.34.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00332">
        <property type="entry name" value="DnaK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012725">
        <property type="entry name" value="Chaperone_DnaK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018181">
        <property type="entry name" value="Heat_shock_70_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029048">
        <property type="entry name" value="HSP70_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029047">
        <property type="entry name" value="HSP70_peptide-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19375">
        <property type="entry name" value="PTHR19375"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100920">
        <property type="entry name" value="SSF100920"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100934">
        <property type="entry name" value="SSF100934"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02350">
        <property type="entry name" value="prok_dnaK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00297">
        <property type="entry name" value="HSP70_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00329">
        <property type="entry name" value="HSP70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01036">
        <property type="entry name" value="HSP70_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="evidence at transcript level"/>
    <keyword evidence="5 7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4 7 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3 7" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7" id="KW-0346">Stress response</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="608"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="627"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="modified residue" description="Phosphothreonine; by autocatalysis" evidence="7">
        <location>
            <position position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00014415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC94915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="647" mass="69740" checksum="46EC857E2234B1FF" modified="2018-07-18" version="1">MGRIIGIDLGTTNSCVSVVENGIPKVIENAEGARTTPSIIAYQEDGEILVGASAKRQAVTNPKNTLYAVKRLIGRKYDEKEVQKDIGLMPYAIVKAENGDAWVSVRDKKMAPPQISAEVLRKMKKTAEDYLGEEVTEAVITVPAYFNDAQRQATKDAGRIAGLEVKRIINEPTAAALAFGLDKAERGDRKIAVYDLGGGTFDVSIIEIADVDGEMQFEVLSTNGDTFLGGEDFDQRIIDYIIEEFKKINGLDLSKDAIALQRIKASAERAKIELSSTQQTEINEPYIAMANGAPVHLNLKMTRAKLESLVEELISKTIEPCRIAIRDAGVKTTDIDDIILVGGMTRMPKVQEIVKDFFGKEPRKDVNPDEAVAAGAAIQGSVLSGDRKDLLLLDVTPLSLGIETLGGVMTKMIQKNTTIPTKFSQVFSTADDNQPAVTIKVFQGEREIAAGNKGLGEFNLEGIPPSARGTPQIEVTFDIDANGILHVGAKDKATGKENKITIKANSGLTEEEIQKMVKDAELNAEEDKKVKELAESRNQGDALVHSTRKALTEHGDKLEAGEKEKIDASIKELEDSLKSGDKVSIDAKIAALSTASQKLGEKMYADMQASQAAGAAGDAGAGAAGASEAKHHEDDVMDAEFKEVKDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4T4</accession>
    <name>A0A2S9H4T4_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Cobalamin biosynthesis protein CobD</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">cobD</name>
        <name evidence="11" type="ORF">S2091_0184</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 10">Cofactor biosynthesis; adenosylcobalamin biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 10">Cell membrane</location>
            <topology evidence="2 10">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the CobD/CbiB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94989">
        <property type="protein sequence ID" value="PRC94989"/>
        <property type="gene ID" value="S2091_0184"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00148"/>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015420">
        <property type="term" value="F:ABC-type vitamin B12 transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048472">
        <property type="term" value="F:threonine-phosphate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009236">
        <property type="term" value="P:cobalamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00024">
        <property type="entry name" value="CobD_CbiB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031347">
        <property type="entry name" value="AmpE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004485">
        <property type="entry name" value="Cobalamin_biosynth_CobD/CbiB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34308">
        <property type="entry name" value="PTHR34308"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17113">
        <property type="entry name" value="AmpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03186">
        <property type="entry name" value="CobD_Cbib"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 10" id="KW-0169">Cobalamin biosynthesis</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="49"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="75"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="150"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="193"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="296"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC94989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="318" mass="35603" checksum="3A9014C9DBD0A5D1" modified="2018-07-18" version="1">MTFLSILCALLIEQLKPLRADNPIYTAIKALAMRIEAWCNAGEPQNGRLGWWITVAILTVPTALIYWICLHKLNIFAALLWNIIIVYLTLGFRHYSHYFTSIQLALHSGDEETARTLLAEWTHTDTTGLDVSEIARLAVEKSLITTHRSVFGVFFWFLMPVGPACAVMYRVAEHLSRAWNEPQHMKNEAFGQYAARIFYIIDWIPARLTAIAFAVVGNFEDAIYAWRNFAHRWKNESEGIILASGSGALGVRLGSPEENAVELPIDAAIVDSVGIEPEVMPGEPAGIRSLQSAVGLVWRALLLWMLLLLLLSMAVWLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4Y0</accession>
    <name>A0A2S9H4Y0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0237</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95042">
        <property type="protein sequence ID" value="PRC95042"/>
        <property type="gene ID" value="S2091_0237"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC95042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="151" mass="16656" checksum="8605BFF13F65A518" modified="2018-07-18" version="1">MTTDTIDHATLERLVEAGVVHGAKIIGQPGGWGVVIQYGMTERGLAAKRGALRIFRKFETLVAYLKDIGIAKYQVDASHFDPVAQKTDRKRADAAERMKNAHEAAAYQGWLTQQVQEAIDDPRPSVPQSAVEAEWAIERAALLKRAESMGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H517</accession>
    <name>A0A2S9H517_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Amidases related to nicotinamidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0275</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95080">
        <property type="protein sequence ID" value="PRC95080"/>
        <property type="gene ID" value="S2091_0275"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.850">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000868">
        <property type="entry name" value="Isochorismatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036380">
        <property type="entry name" value="Isochorismatase-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00857">
        <property type="entry name" value="Isochorismatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52499">
        <property type="entry name" value="SSF52499"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Isochorismatase" evidence="1">
        <location>
            <begin position="21"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC95080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="216" mass="22895" checksum="337D24B1EDFABBCF" modified="2018-07-18" version="1">MLNKTGSIGGTECALQFGKKTALVLIEYQDEWLAPGGKLNALMQDRSQFTDATLTSQRLIAGARAQGLPIIHVGLKFNVGYPELGKAQYGLREAIPRVGTFVGTGATFTPPFTPQTGEFVVSGRNGASAFASSNLDSYLRNQGIDTLLIAGFALHVCVESTLRQAHDLGYTAIVVSDATAAFTPEQRAHVLSDVVHHYGTSTSADAALSQLRGLTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H536</accession>
    <name>A0A2S9H536_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA polymerase III subunit delta</fullName>
            <ecNumber evidence="1">2.7.7.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_0295</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="1"/>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95100">
        <property type="protein sequence ID" value="PRC95100"/>
        <property type="gene ID" value="S2091_0295"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009360">
        <property type="term" value="C:DNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008921">
        <property type="entry name" value="DNA_pol3_clamp-load_cplx_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032780">
        <property type="entry name" value="DNA_pol3_delt_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010372">
        <property type="entry name" value="DNA_pol3_delta_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005790">
        <property type="entry name" value="DNA_polIII_delta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14840">
        <property type="entry name" value="DNA_pol3_delt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06144">
        <property type="entry name" value="DNA_pol3_delta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48019">
        <property type="entry name" value="SSF48019"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01128">
        <property type="entry name" value="holA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="3" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DNA_pol3_delta" evidence="5">
        <location>
            <begin position="25"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="domain" description="DNA_pol3_delt_C" evidence="6">
        <location>
            <begin position="218"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00017703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00024632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF06144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF14840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC95100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="342" mass="37814" checksum="7A97137113BD65F3" modified="2018-07-18" version="1">MQLRLDALDAQLAKSLAPLYVVSSDEHLLAQQALDKIRAKARAEGFAEREILTVERSFKWGALLAANQSQSLFGDKKIIDLRIPTGKPGKDGAAALTDYVTQLKNNPNPDNITIISLPKLDWASQKSAWVTRLQDAAVYLDIPLVERAQLSGWIARGLKEQGQSTEREALEFIADRVEGNLLAAHQEIQKLGLLYPAGTLTTVQIQEAVLNVARYDVFKLSEAILQGDIARLVRMLDGLKGEGEALPLVLWALAEECRTLLKLKIGMQEGRPLSAMFKEQRIWGGRERLMEPALRRLSLSTLQNALQNAAQIDKLIKGLRVKKLSGDAWDAVLQLSLSLARA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5D1</accession>
    <name>A0A2S9H5D1_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Glutamate--tRNA ligase</fullName>
            <ecNumber evidence="8">6.1.1.17</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Glutamyl-tRNA synthetase</fullName>
            <shortName evidence="8">GluRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">gltX</name>
        <name evidence="12" type="ORF">S2091_0389</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>ATP + L-glutamate + tRNA(Glu) = AMP + diphosphate + L-glutamyl-tRNA(Glu)</text>
            <dbReference type="Rhea" id="RHEA:23540"/>
            <dbReference type="Rhea" id="RHEA-COMP:9663"/>
            <dbReference type="Rhea" id="RHEA-COMP:9680"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78520"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.17"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="8">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.17" evidence="8"/>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95194">
        <property type="protein sequence ID" value="PRC95194"/>
        <property type="gene ID" value="S2091_0389"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004818">
        <property type="term" value="F:glutamate-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006424">
        <property type="term" value="P:glutamyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00808">
        <property type="entry name" value="GluRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00022">
        <property type="entry name" value="Glu_tRNA_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045462">
        <property type="entry name" value="aa-tRNA-synth_I_cd-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020751">
        <property type="entry name" value="aa-tRNA-synth_I_codon-bd_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008925">
        <property type="entry name" value="aa_tRNA-synth_I_cd-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004527">
        <property type="entry name" value="Glu-tRNA-ligase_bac/mito"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000924">
        <property type="entry name" value="Glu/Gln-tRNA-synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020058">
        <property type="entry name" value="Glu/Gln-tRNA-synth_Ib_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033910">
        <property type="entry name" value="GluRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19269">
        <property type="entry name" value="Anticodon_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00749">
        <property type="entry name" value="tRNA-synt_1c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00987">
        <property type="entry name" value="TRNASYNTHGLU"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48163">
        <property type="entry name" value="SSF48163"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00464">
        <property type="entry name" value="gltX_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 8 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 8 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 8 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 8 9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="tRNA-synt_1c" evidence="10">
        <location>
            <begin position="2"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="domain" description="Anticodon_2" evidence="11">
        <location>
            <begin position="323"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'HIGH' region" evidence="8">
        <location>
            <begin position="9"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'KMSKS' region" evidence="8">
        <location>
            <begin position="241"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="244"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF19269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PRC95194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="461" mass="51305" checksum="57B4C3BA192ED68D" modified="2018-07-18" version="1">MKVRTRFAPSPTGYLHLGGARTALFSWAFARHFGGTFVLRIEDTDLERSTPEAVQAIIEGMEWLGLQHDEGPFYQMKRMERYSAVLAEMLAAGSAYHCYSSPEEVEAMREKQRAIGEKPRYDGTWRPEAGKTLPSIPADRKPVIRFKNPLDGEVTWDDVVKGQITIANREMDDLVIARPDGTPTYNFCVAVDDWDMQITHVIRGDDHVNNTPRQINILQALGATLPKYGHVPMILGADGEKLSKRHGAVSVMDYPAQGYLPEAMLNYLSRLGWSHGDDEVFSMEQMCSWFNLDHLSKSPAQFNPEKLAWLNNHYIKLADNSRLAGLVKPAMPDAQFDGAPPLDAVIGLLKERANTTVELANSAMLFYRQPQPDAALLVQHLTDAVRPALQSFVEQCATVAWNKADLSALMKSTLAAHGLKMPQLAMPLRLLVTGQLQTPSIDAVLELFGRDVVVSRILQGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5I8</accession>
    <name>A0A2S9H5I8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Gram-negative porin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_0331</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95136">
        <property type="protein sequence ID" value="PRC95136"/>
        <property type="gene ID" value="S2091_0331"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046930">
        <property type="term" value="C:pore complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015288">
        <property type="term" value="F:porin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006811">
        <property type="term" value="P:ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00342">
        <property type="entry name" value="gram_neg_porins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033900">
        <property type="entry name" value="Gram_neg_porin_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023614">
        <property type="entry name" value="Porin_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13609">
        <property type="entry name" value="Porin_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0406">Ion transport</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0626">Porin</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1134">Transmembrane beta strand</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015541021" evidence="4">
        <location>
            <begin position="21"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="domain" description="Porin_4" evidence="5">
        <location>
            <begin position="7"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF13609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC95136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="430" mass="45860" checksum="F9955A3FFF5D1F15" modified="2018-07-18" version="1">MKKSLLALAVMSMATTFAHADTTVQLYGILDEGFAHIEHSLPANDQFAFSLNPYNVTAQNQSSVNALVSGGASMSRWGIQGNEDLGGGMKTFFKLESAMNLGSGQIANNGQTVLNNANSLSTISGAAAINGQLFSRAAYVGLGDATWGSIELGRTTAFSFDQTSEFDPLHGSGLYSLIGFSGATGGGLGLTENSRLDNSLKYENKIGDVGFGLQYKIANTNSSEADDVGSVLEGMLSYKSGSFSLEATASQAKNTPALSFKLFTNDVGLRVSDTSGYMLTAKFEVTPQSTVRAGIERTSQSTPSSSNNWNTQITNYYGMSIAGLVTAKAFDPTWGSAVVTTAWIGEGYQFTDKFTLDAGYYNINNAANNHNDQYTIQALSMMADYSFTKHTDLYAGLMLAHYSGEYLVQQSPPTLATRNAIFGTGLRVRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5L3</accession>
    <name>A0A2S9H5L3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">TonB family C-terminal domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_0469</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95274">
        <property type="protein sequence ID" value="PRC95274"/>
        <property type="gene ID" value="S2091_0469"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006260">
        <property type="entry name" value="TonB/TolA_C"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01352">
        <property type="entry name" value="tonB_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="40"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="84"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="147"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="147"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="208"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC95274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="323" mass="35832" checksum="96F5B5610FCD6D98" modified="2018-07-18" version="1">MSERVNINRAQVNGNGTLGVADSLTGSHYQIPKEPGRNSAFLLAGVMHVLLFMFLWIGIRWQSQEPVGVDAEIWDMTTREAAPLPKIEVAPPQPPEVEKTEPELTSKQVAQEQEQEQEAEIAIERARKQKIADEKLIEKKKIEDQLKEKQKEDQLKEKQKEEKLQEAKDEQKRKDDLQKDQKKQDLAKAAEQKKADALAKKQRDDNLKNLTSQVVGTGGTGDAVKSTGNNRVDPSYAGKIAAKIKSKMVYLGSDNGPDNPTVEFKIDLFPDGSLRGVPHKTKSSGVAQFDDAVDSAIRNAAPYPADKSGVVPQTIPLTYKLKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSL9</accession>
    <name>A0A2S9GSL9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_4548</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000037">
        <property type="protein sequence ID" value="PRC90722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90722">
        <property type="protein sequence ID" value="PRC90722"/>
        <property type="gene ID" value="S2091_4548"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC90722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="306" mass="33937" checksum="CC928F1D9BC3202E" modified="2018-07-18" version="1">MNKLQAMEVFVEVVDAGGFTRAAEHLQMPKATVTTLIQSLEKELAVKLLHRTTRHISVTADGAAYYERCLRILSDVREAEESLSRNRASPRGRLRVDVSTGMASAILIPALPDFFERYPDIALELGCSDRPVDLIEEGVDCAVRGGNLGDSNLIARRIGVINFATCASVDYLAKFGRPAHPRDLEQHQCVNYFSSKTGKTMDWDFTRDGERIEMSMRGKIAVNDSNAYASAGLAGLGIVQMTDFQMAPYLANGHFELLLKEWTTDPLPIHVVYPQNRHLSAKVRVFVEWIAELFSSQSGVSTSRSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GST1</accession>
    <name>A0A2S9GST1_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Flagellar M-ring protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">S2091_4525</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">The M ring may be actively involved in energy transduction.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Bacterial flagellum basal body</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the FliF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000036">
        <property type="protein sequence ID" value="PRC90777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90777">
        <property type="protein sequence ID" value="PRC90777"/>
        <property type="gene ID" value="S2091_4525"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009431">
        <property type="term" value="C:bacterial-type flagellum basal body, MS ring"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003774">
        <property type="term" value="F:cytoskeletal motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071973">
        <property type="term" value="P:bacterial-type flagellum-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013556">
        <property type="entry name" value="Flag_M-ring_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000067">
        <property type="entry name" value="FlgMring_FliF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006182">
        <property type="entry name" value="FliF_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043427">
        <property type="entry name" value="YscJ/FliF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30046">
        <property type="entry name" value="PTHR30046"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30046:SF0">
        <property type="entry name" value="PTHR30046:SF0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01514">
        <property type="entry name" value="YscJ_FliF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08345">
        <property type="entry name" value="YscJ_FliF_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004862">
        <property type="entry name" value="FliF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01009">
        <property type="entry name" value="FLGMRINGFLIF"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00206">
        <property type="entry name" value="fliF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0975">Bacterial flagellum</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="14" id="KW-0966">Cell projection</keyword>
    <keyword evidence="14" id="KW-0969">Cilium</keyword>
    <keyword evidence="14" id="KW-0282">Flagellum</keyword>
    <keyword evidence="7 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="25"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="455"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="domain" description="YscJ_FliF" evidence="12">
        <location>
            <begin position="46"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="domain" description="YscJ_FliF_C" evidence="13">
        <location>
            <begin position="255"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="281"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR004862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF08345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="PRC90777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="559" mass="61014" checksum="B3EEB5299B5C240E" modified="2018-07-18" version="1">MATADPATLAQPRFLGLPETQGTRLFLLVGSTAAVLAVMAGIWIWSSQPDYRVLFSNYTDRDGGAIVASLQQMNVPYKFSEGGTAILVPENQVHDARLKLALQGLPKGGNVGFELMENQKMGISQFLEQINFQRALEGELARSIETISAVQSARVHLAIPKDTVFMREQQKPTASVILNLYSSRLLDQQQVSAIIHLVASSVPELPAQNVTIVDQSGNLLSDTTKQTSNGLNPTQLKYVHELQQDIVKRIESIISPIVGPNNVRAEASADVDFTHVEQAAETYKPNQPPETASVRSMQNSESGNKSATNASGIPGSFSNQPPTNATAPIVTGAAAASAAAAANGAVTQKESTINYELDKTVRYTQLAMGGIKRLAVGVVVNFKHEIDKNGKPVNRELNDAEKAQITSLAKEAMGFSQERGDTLNVVNSQFISTEKDLADVPFWKQPATIELIKNILKYLAGAIAIMYLFFGYLKPLLRKIMDRNAAREREEARYRATPNLDEQLNEDGSVVNLSKPEVVEEFQFKAAHAYEKDLEVAQNLAKQDPKIVANVVKTWVNSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSY9</accession>
    <name>A0A2S9GSY9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4493</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000035">
        <property type="protein sequence ID" value="PRC90830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90830">
        <property type="protein sequence ID" value="PRC90830"/>
        <property type="gene ID" value="S2091_4493"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC90830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="395" mass="43544" checksum="3961FC83CC78E79B" modified="2018-07-18" version="1">MDVVELIATWKQRLAAITANANELSEAESTKRIRIRAREGRYQGLTQQRAEAAIAQISMLRDDYLLLARVVDEAVQAHQGGLFTSRETRDEKVVALLCSPSISRATGPVPIEKRTLLGSANHHDQMTPDQLLTLMQKEFELARDLLNAIDSAEAEGALELDGLRHDFVGMEERAARLQAGSDRPSFIELQDLQSDPLNAKAGMDSLKRGLQAWSASLDDLEHVRVSAQDAVVRAKTALGDLNRLSGDYQMQLMQFKELFGESTPLKLMPGMQIEMLSSWCGTLENMLIAGQWNAVNVGASRLNIAMNEAIGNVNLAIAEVQTKCAEVDELKGHFNALRAKEKALFGQEVQGVANEAASLLRGQIEAMLKSRPLDLDGARSLIQKYQNIMLTIGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GT23</accession>
    <name>A0A2S9GT23_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phage head completion protein (GPL)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4448</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000034">
        <property type="protein sequence ID" value="PRC90867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90867">
        <property type="protein sequence ID" value="PRC90867"/>
        <property type="gene ID" value="S2091_4448"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019069">
        <property type="term" value="P:viral capsid assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009225">
        <property type="entry name" value="Phage_head_completion_GpL"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05926">
        <property type="entry name" value="Phage_GPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC90867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="164" mass="18463" checksum="C3C6E765D0089087" modified="2018-07-18" version="1">MDSMSFSAFAPPTNSVPDDQQIVENDGWFPAIHLSDLREAARLDGTVTDARLTPAVVTAMLAVNQALAEWQARQRINGWSDLASVPAPTINRESQYLAHYRRAVYSTTKADLLEKYRDYDSTASSMSDKKAMEWLDTAPEQERRNAHWAIANILQQPHMTVELI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTI2</accession>
    <name>A0A2S9GTI2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4294</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000031">
        <property type="protein sequence ID" value="PRC90998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90998">
        <property type="protein sequence ID" value="PRC90998"/>
        <property type="gene ID" value="S2091_4294"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="206" mass="21168" checksum="AE55800E0E6C0D32" modified="2018-07-18" version="1">MSFVSAISASQPSFVSSTAQSDGQQIPASQPQSSGGASSVAISAAGQTYLNYEQTMAIDQQNQSRTIASADSDPQWGAGLASAMAHDTSMDGSAVGGLVSISAPFGDPVTYTNGAPVTVASQAYFTKQYASYQNQVTQLYNSDSAKGTPPGQIISDIFALQAKQPDAFRAMMSWPPGSGPLSVQQATNVPGSVPQYLNAGGQVIQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTL2</accession>
    <name>A0A2S9GTL2_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glycoamylase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4247</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000030">
        <property type="protein sequence ID" value="PRC91059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91059">
        <property type="protein sequence ID" value="PRC91059"/>
        <property type="gene ID" value="S2091_4247"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019282">
        <property type="entry name" value="Glycoamylase-like_cons_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016883">
        <property type="entry name" value="UCP028431"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10091">
        <property type="entry name" value="Glycoamylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028431">
        <property type="entry name" value="UCP028431"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycoamylase-like" evidence="1">
        <location>
            <begin position="180"/>
            <end position="415"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF10091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="432" mass="49262" checksum="7C92E33F9B4BE1DE" modified="2018-07-18" version="1">MNHRILSEDDELEILQRESYRYFKHETNPENGLVIDKSAPDWPSSIAAVGLALTGYPVAVERGFITRDEAIKLVSTTLRFFWQSPQGPEPDATGYHGFYYHFLDMQTGRRTWNCELSTIDSAFLLAGALTCGEYFNADNVDEKEIRTLANALYQRADWQWVRAEDNTVSMGWTPENGFLPYKWTGYDEALLLYILGLGSPTYPLPESSYLNWTSGYQWQHSYGYSYLYSAPLFAHQLSHIWVDFRGIQDVYMQDKGIDYFENSRRATLIQQQYAIHNPHGFAGYGEFCWGFTASDGPGPRVVHINGIKHEFFDYIARGAPNGVDDGTISPWVAVASLPFAPEIVLPTIDHFVHQIGLKAGNPYGFKSTFNPTYPCNAHAVYGWMSPWHFAINEGPILLMVENYRSELIWNLMRKNSYIIQGLKRAGFIGGWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTL7</accession>
    <name>A0A2S9GTL7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4224</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000030">
        <property type="protein sequence ID" value="PRC91036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91036">
        <property type="protein sequence ID" value="PRC91036"/>
        <property type="gene ID" value="S2091_4224"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="84" mass="9005" checksum="B07D510EC72504A3" modified="2018-07-18" version="1">MATCANQVSNSDGSLSLVLMPTQPDLSQCQFAVMSGSEVINSQFLQLTPAEASHISSFVLLVWGTAWGFKQLANFIKGDTHVSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTV2</accession>
    <name>A0A2S9GTV2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4153</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000028">
        <property type="protein sequence ID" value="PRC91152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91152">
        <property type="protein sequence ID" value="PRC91152"/>
        <property type="gene ID" value="S2091_4153"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="49" mass="5365" checksum="1ECD07828FACECB2" modified="2018-07-18" version="1">MNIFSDHQTIVEGSAVAVLLLLPAFGMQSAYGHEYTALIKAKKYAEVTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTZ7</accession>
    <name>A0A2S9GTZ7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">K+-transporting ATPase, F subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4074</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000027">
        <property type="protein sequence ID" value="PRC91179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91179">
        <property type="protein sequence ID" value="PRC91179"/>
        <property type="gene ID" value="S2091_4074"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008556">
        <property type="term" value="F:P-type potassium transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043462">
        <property type="term" value="P:regulation of ATP-dependent activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011726">
        <property type="entry name" value="KdpF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09604">
        <property type="entry name" value="Potass_KdpF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02115">
        <property type="entry name" value="potass_kdpF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="29" mass="3185" checksum="9A8B6B097DCE14DA" modified="2018-07-18" version="1">MNSLLIIAGIIAALLFVYLVYALLKAETF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GU08</accession>
    <name>A0A2S9GU08_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">3-octaprenyl-4-hydroxybenzoate carboxy-lyase</fullName>
            <ecNumber evidence="4">4.1.1.98</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Polyprenyl p-hydroxybenzoate decarboxylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ubiD</name>
        <name evidence="5" type="ORF">S2091_4107</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>a 4-hydroxy-3-all-trans-polyprenylbenzoate + H(+) = a 2-all-trans-polyprenylphenol + CO2</text>
            <dbReference type="Rhea" id="RHEA:41680"/>
            <dbReference type="Rhea" id="RHEA-COMP:9514"/>
            <dbReference type="Rhea" id="RHEA-COMP:9516"/>
            <dbReference type="ChEBI" id="CHEBI:1269"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:78396"/>
            <dbReference type="EC" id="4.1.1.98"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>prenyl-FMN</name>
            <dbReference type="ChEBI" id="CHEBI:87746"/>
        </cofactor>
        <text evidence="4">Binds 1 prenylated FMN (prenyl-FMN) per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Cofactor biosynthesis; ubiquinone biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homohexamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the UbiD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.98" evidence="4"/>
    <dbReference type="EMBL" id="PUGF01000027">
        <property type="protein sequence ID" value="PRC91212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91212">
        <property type="protein sequence ID" value="PRC91212"/>
        <property type="gene ID" value="S2091_4107"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00232"/>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008694">
        <property type="term" value="F:3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006744">
        <property type="term" value="P:ubiquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01636">
        <property type="entry name" value="UbiD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002830">
        <property type="entry name" value="UbiD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023677">
        <property type="entry name" value="UbiD_bacteria"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30108">
        <property type="entry name" value="PTHR30108"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01977">
        <property type="entry name" value="UbiD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00148">
        <property type="entry name" value="TIGR00148"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0288">FMN</keyword>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-0464">Manganese</keyword>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0831">Ubiquinone biosynthesis</keyword>
    <feature type="region of interest" description="Prenyl-FMN binding" evidence="4">
        <location>
            <begin position="175"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Prenyl-FMN binding" evidence="4">
        <location>
            <begin position="189"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Prenyl-FMN binding" evidence="4">
        <location>
            <begin position="194"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="4">
        <location>
            <position position="294"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="172"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="238"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC91212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="494" mass="55183" checksum="BA122D4FC4295017" modified="2018-07-18" version="1">MKYEDLRDFIAKLKIEGELKEINTPISPILEMTEVCDRTLRAEGPALLFTQPTGFDIPVLGNLFGTTRRVALGMGAQDLTELRKIGHVLASLKEPEPPKGFKDLLGLGSLVKAVWDMAPKELRSAPCQTIVWEGAQVDLGRLPIQHCWPGDVAPLITWGLVITKGPFKKRQNLGIYRQQVLSRNKVIMRWLAHRGGALDFREHGIVNKGQPYPVAVALGADPATILGAVTPVPDSLSEYQFAGLLRGSRTELVKAIGSELRVPASAEIVLEGHIYPDANHPSGYEHALEGPYGDHTGYYNEQDSFPVFTIDRITMRENPIYHSTYTGKPPDEPAVLGVALNEVFVPLLQKQFSEITDFYLPPEGCSYRMAIVQIKKSYAGHAKRVMFGVWSFLRQFMYTKFIIVVDEDVNIRDWKEVMWAITTRVDPLRDTTLVDNTPIDYLDFASPVSGLGSKMGLDATNKWPGETNREWGQVITMSPDVKKRIDGIWQELGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GU33</accession>
    <name>A0A2S9GU33_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4106</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000027">
        <property type="protein sequence ID" value="PRC91211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91211">
        <property type="protein sequence ID" value="PRC91211"/>
        <property type="gene ID" value="S2091_4106"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="68" mass="7195" checksum="688C391F1D41A956" modified="2018-07-18" version="1">MRTTDNSGAKMYAVEIEQIHTDISKMMAETAKLNSEASWYPIIVAVGIMGGTAAVLAGIAAFVNAFSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GU62</accession>
    <name>A0A2S9GU62_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Nitrogen regulatory protein PII</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_4060</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the P(II) protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000026">
        <property type="protein sequence ID" value="PRC91275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91275">
        <property type="protein sequence ID" value="PRC91275"/>
        <property type="gene ID" value="S2091_4060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030234">
        <property type="term" value="F:enzyme regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006808">
        <property type="term" value="P:regulation of nitrogen utilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002187">
        <property type="entry name" value="N-reg_PII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011322">
        <property type="entry name" value="N-reg_PII-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015867">
        <property type="entry name" value="N-reg_PII/ATP_PRibTrfase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017918">
        <property type="entry name" value="N-reg_PII_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002332">
        <property type="entry name" value="N-reg_PII_urydylation_site"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30115">
        <property type="entry name" value="PTHR30115"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00543">
        <property type="entry name" value="P-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039144">
        <property type="entry name" value="GlnB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00340">
        <property type="entry name" value="PIIGLNB"/>
    </dbReference>
    <dbReference type="SMART" id="SM00938">
        <property type="entry name" value="P-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54913">
        <property type="entry name" value="SSF54913"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00638">
        <property type="entry name" value="PII_GLNB_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51343">
        <property type="entry name" value="PII_GLNB_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00496">
        <property type="entry name" value="PII_GLNB_UMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="modified residue" description="O-UMP-tyrosine" evidence="2">
        <location>
            <position position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR039144-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR602187-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC91275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="112" mass="12226" checksum="76C6F563B5EA1CD4" modified="2018-07-18" version="1">MKQITAIIKPFKLDEVRESLAEVGVTGLTVTEVKGFGRQKGHTELYRGAEYVVDFLPKIKVEVVVDDLAVENAVDAIIKAARTGKIGDGKIFVQNIEQVVRIRTGETGSEAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GU83</accession>
    <name>A0A2S9GU83_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Heme biosynthesis-associated TPR protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">S2091_4055</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in a late step of protoheme IX synthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Porphyrin-containing compound metabolism; protoheme biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell inner membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000026">
        <property type="protein sequence ID" value="PRC91270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91270">
        <property type="protein sequence ID" value="PRC91270"/>
        <property type="gene ID" value="S2091_4055"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00252"/>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042168">
        <property type="term" value="P:heme metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006779">
        <property type="term" value="P:porphyrin-containing compound biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005254">
        <property type="entry name" value="Heme_biosyn_assoc_TPR_pro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010817">
        <property type="entry name" value="HemY_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07219">
        <property type="entry name" value="HemY_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00540">
        <property type="entry name" value="TPR_hemY_coli"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="39"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="domain" description="HemY_N" evidence="12">
        <location>
            <begin position="26"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF07219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PRC91270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="401" mass="45320" checksum="40B731B1049FD8A2" modified="2018-07-18" version="1">MGFFIRLVILFATAVLVALSARFNPGNVVLFYPPYRIDMSLNLFILVLLVIFALLGLLFYTINATKQMPERVATYRRSKSEREGNKALRDALKAFFEGRFGHAEKAAMRAAELPENTALASLIGARAAHNMSQSERRDAWLAGIEDNQQYKVARLVSTTELLVDAHQSEQALEAVKELNANGTRHIHVLRWALKANQQAKQWTEVLRLVKALDKHRSLHPALSTRLRELAYQDLLSDHGQDAESIRRLWYSIPAEDRVKPFVAALAARTMVAQGLFDEARNLLEKALLVDWDERLIVAYREAAAKEGSAALLTQIEHCESWLVIHPTDPELALTMGVLCLNQKLWGKAERNLEQALMYASDITCLRETNLKLAQLNEQLGLQEKAAEYYRACALIAERKFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GU98</accession>
    <name>A0A2S9GU98_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_3959</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000025">
        <property type="protein sequence ID" value="PRC91288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91288">
        <property type="protein sequence ID" value="PRC91288"/>
        <property type="gene ID" value="S2091_3959"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="9"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="148"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC91288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="216" mass="24130" checksum="9565B3469C3D6EFD" modified="2018-07-18" version="1">MLKDNAIIEVIIADDHAIVREGLKQILADTKDIIVRGEAECGLTTIKMCREHEFDVLLLDISMPDKSGIEVLKQIKKEHPNIAVVMLSMHPEDQYAIRSLKAGASGYLNKQSAPKELVTAIRQVASGLKYINASVAQELANHIDEEHQVTLHETLSDREYQTLTLIASGKAVSDIAKELSLSVKTISEYRSRVLFKMKLKNNAELTHYAIKNQLID</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUB6</accession>
    <name>A0A2S9GUB6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3969</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000025">
        <property type="protein sequence ID" value="PRC91298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91298">
        <property type="protein sequence ID" value="PRC91298"/>
        <property type="gene ID" value="S2091_3969"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015454941" evidence="1">
        <location>
            <begin position="21"/>
            <end position="435"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="435" mass="46442" checksum="47F36F660BFA6C8A" modified="2018-07-18" version="1">MYKKYSTVAIWLLATGFISAACADNVTPPDTMTMPKQSIFSFSSFGTIGVVQTNTDNGIYTTGTEKNGATTSSDFGPDTKLGGQLDAKFNDYLSATVQLFSKQNAVGSYNPDVEWAFGKLKMGNGFSLRLGRIGAPFFMSSDFRNVGYTNITVRTPVDVYALVPVRSFDGGDILYETSLGNTTLNGQFWMGRSSVLEGENASGDEQILLHNIAGINFSAENGPFTVRFGTMKTRLGTSGTGLNGFNGLLGELNQASGLLPALSSLGTIANDLAIDNKFATFTDLGIIFDSGNWIASSEVVKRKTESTYISTVTAWYATLGYRIQKFTPYLSFSGRNVNSVTSVSAPAITPLLPAVDQQAVLALVGGANSLLISTNEKTGALGVRWDAGKNYDIKAEYQQIQVPAGSAGIFSKVTGGSYTTDTHVSVFSLCLDFVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUE6</accession>
    <name>A0A2S9GUE6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Succinyldiaminopimelate transaminase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3999</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000025">
        <property type="protein sequence ID" value="PRC91328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91328">
        <property type="protein sequence ID" value="PRC91328"/>
        <property type="gene ID" value="S2091_3999"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009016">
        <property type="term" value="F:succinyldiaminopimelate transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019878">
        <property type="entry name" value="DapC_beta/gammaproteobac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03538">
        <property type="entry name" value="DapC_gpp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="1">
        <location>
            <begin position="32"/>
            <end position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="404" mass="44569" checksum="DAC200403ECB3831" modified="2018-07-18" version="1">MNQLLNQLQPYPFEKLKQLFHGITPPNHLTPISLGIGEPKHATPELINAALIENLSGLASYPGTQGSEVLRQAIAAWISRRYQIPALNPNTQILPVNGSREALFAFAQTVLDTSKGTAPPLVMCPNPFYQIYEGAAYLAGAEPYFVNADETRNYSPDYASVPEHIWERVQLLFVCSPGNPTGAVLSLDDWKQLFELSDRYGFVIAADECYSEIYFGDTAPLGALEAAHQLGRTTFPRLVSFSSLSKRSNVPGMRSGFVAGDADIIKLFLLYRTYHGSAMSPVIQAASAIAWTDEQHVIQNRALYKAKFAQVTPLLQQVLDVELPDAGFYLWARVDKLVSISDTAYAQQLYAEYNVTVLPGSFLAREAHGINPGQQRIRMALVASVDECLEAAQRIVAFTRQLAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUJ1</accession>
    <name>A0A2S9GUJ1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">SNF2 family N-terminal domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_3950</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000024">
        <property type="protein sequence ID" value="PRC91405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91405">
        <property type="protein sequence ID" value="PRC91405"/>
        <property type="gene ID" value="S2091_3950"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140658">
        <property type="term" value="F:ATP-dependent chromatin remodeler activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0347">Helicase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="2">
        <location>
            <begin position="921"/>
            <end position="1074"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="3">
        <location>
            <begin position="1198"/>
            <end position="1353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC91405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="1360" mass="151991" checksum="78BFAF0037651678" modified="2018-07-18" version="1">MQKIPHIHSEIPADTLPVLFALALWEMPLSQSRLLDFLQSSLAAQGVAKKFNAVNIKTSVATLAELGLIGFLPGFGYQATQEVSHAVFLHLLQTNELVRWIREVQEFLNRNREYSTWATPTSLFCQREMLFSVLIDDLPRFGQWRAQFFAFANTYDDLPAKKLFATPAGAQLFTHIKPNLQAQLLIDLFAAASWMLEDCTSAYHYAKEQSETVFKNEFLLMEAICTQAILRGEPDALLQKLIPQMRGASYPLAISKLLKGDFSTSAEIFSIIHTANKQITGKRKLFIPDLAGLFYSAAQLANNTPAHLKLAKEQCDEGSKHRQSQFYPAIKPLIEHLMRGTPLSTKSNGNYHQSLDDFFVRLAYFWQDCPVTETDRRNLQRLSALSQQHGYMWVAAELDQLCNAQFNEPEQFHGWHQAHQLKPLCMALQREEAWQRALSALSQLKTAAQSGADTRIAWFLECESHYVNLEPREQKRSAKGVWSKGRPVALKRLSYEQDSLPGIIEQDKKIATCIKKSYDNYYGGSDYELNGEKALPFLIGHPAVYWLDAPDVKIDILKGEPALTMKQHGSTISLQLEPDMNADEAVIWRKQTPTRLVVYPSNPELKQIAGIIGKGLSVPSNAKEQLVAVIAAIAPHLAIHSDLPELAQHIDSIPADTTLYAHLLPLKEGLRVQFLMRPLPEGSWMTPGKGSVNVLGEHQGKTVQASRSLETEQVQLNAVLKNCPALNQAEQNGQEWEFGHPETCLELLSQLSTFKAESNGSLELVWPEGERFRIKATRSLSQLNLSIKKQGEWFVAGGEIKLDDGKVMALRELLHLVDGATGRFLPLGDNHFLALTDSFKKRLQELNALSEPSGKDGVRVNHLAAPLLAELADEAGDLKADAAWQAQVEKLNSLADYVPKLPSTLQAKLRDYQLEGYQWLSRLAYWGVGACLADDMGLGKTVQTLAVLLERAPVGPALVVAPISVAMNWQAEVARFAPTLRVRAYHQNRSLNDLGAFDLVIASYGMLQQDAEAFAQPDWHTVVLDEAQVIKNSATKRSQAAMALKADFRIIASGTPVENHLGELWNLFRFINPGLLGSKDRFAERFSTPIEKGDKLARSHLKRLIQPFILRRTKTQVLSELPSRTEITLQVELSEQERHMYEALRQESLEKIANMKPEDGKSMQVLAEITKLRRFCCNPKLVMKNSNVAGSKLAVFAEVTEELLDNNHKALVFSQFVDHLAIVRAWLEEKGISYQYLDGSTPAVERKKRVDAFQAGEGDIFLISLKAGGTGLNLTAADYVIHLDPWWNPAVEDQASDRAHRMGQLRPVTIYRLVAQQTIEEKIIALHAQKRDLADSLLEGGDASAKLDTAALLRLLKEGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUJ5</accession>
    <name>A0A2S9GUJ5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Twitching motility protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3997</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GSP E family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000025">
        <property type="protein sequence ID" value="PRC91326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91326">
        <property type="protein sequence ID" value="PRC91326"/>
        <property type="gene ID" value="S2091_3997"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006321">
        <property type="entry name" value="PilT/PilU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001482">
        <property type="entry name" value="T2SS/T4SS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00437">
        <property type="entry name" value="T2SSE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01420">
        <property type="entry name" value="pilT_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00662">
        <property type="entry name" value="T2SP_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="T2SP_E" evidence="2">
        <location>
            <begin position="193"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS00662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="376" mass="41294" checksum="A629DD7261AE1E07" modified="2018-07-18" version="1">MAMERLFELMKEKQASDMFFAINSPIHLKINGNLLPINNQKMDQANIMALLSEVVSAEDMDKLHRENELNLGIGATGIGRFRLSAFRQRGSISAVFRFVPGHIPALSALRLPGILGELIMEKRGLILLVGSTGSGKSTTIASMLDHRNTQRTGHILTIEDPIEYLFRSKKSIVNQREIGTDSVSLEVALRNSLRQAPDCILIGEIRDEATMASAMSYAQSGHLVLATLHANNSYQALNRIISFFPSEHRTALLLDLSSSIRAVVSQRLIRAVDGGRYPAVEVLLNTRYVADLIAAGDMSEIKEAIDKSLSPGSQTFERALMQLINDGLISQEEGLANADSANNLLWLLNNEQVPGAAEPEPPKVEEASFTEFTLNM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUM3</accession>
    <name>A0A2S9GUM3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PRC-barrel domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3824</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000023">
        <property type="protein sequence ID" value="PRC91409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91409">
        <property type="protein sequence ID" value="PRC91409"/>
        <property type="gene ID" value="S2091_3824"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027275">
        <property type="entry name" value="PRC-brl_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011033">
        <property type="entry name" value="PRC_barrel-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05239">
        <property type="entry name" value="PRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50346">
        <property type="entry name" value="SSF50346"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PRC" evidence="1">
        <location>
            <begin position="42"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="150" mass="16839" checksum="66E9F70067A47BB7" modified="2018-07-18" version="1">MLNTNSDSSPQMLDALENETIAINQNDPIAINQNEPIPPLMGAKTLIGNKVSNAQDEHLGDIKEIMLNMHSGSIAYAVLAHGGVLTMGEKLFAVPWNSMKLDPENHQFILNISKERFENAPGFDSNHWPNMADHIWVDSIQGYYFQRTYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUS8</accession>
    <name>A0A2S9GUS8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Rad3-related DNA helicase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_3879</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000023">
        <property type="protein sequence ID" value="PRC91464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91464">
        <property type="protein sequence ID" value="PRC91464"/>
        <property type="gene ID" value="S2091_3879"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016818">
        <property type="term" value="F:hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006139">
        <property type="term" value="P:nucleobase-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006555">
        <property type="entry name" value="ATP-dep_Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045028">
        <property type="entry name" value="DinG/Rad3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014013">
        <property type="entry name" value="Helic_SF1/SF2_ATP-bd_DinG/Rad3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11472">
        <property type="entry name" value="PTHR11472"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13307">
        <property type="entry name" value="Helicase_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00491">
        <property type="entry name" value="HELICc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51193">
        <property type="entry name" value="HELICASE_ATP_BIND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0347">Helicase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="4">
        <location>
            <begin position="33"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC91464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="674" mass="74859" checksum="63E0333B28E99C09" modified="2018-07-18" version="1">MILTDITPSSNPLELDTHIHDADIERLFGPTGQLGSAVTSYRPRHAQIEMAKAIAQAIVGQTTLIAEAGTGTGKTFAYLAPALLWGGKVIVSTGTKNLQDQLFLRDIPAIRLALGAPVSVALLKGRANYLCHFHLERTQQNGRMTSREDVGYLRDISRFIKMTNSGDKAELSQVPETALIWNLVTSTKENCLGSECQYYQDCFVMKARKEAQKADVVVVNHHLFFADVALKDTGIAELLPSANTVIFDEAHQLPDTATLFFGETISTSHVLELCRDVLAEGLSHARDGAEWAKLVVPLEKAARDLRLCFPPEQVRLSLPQIPSSNEFFPALETVKEKLETLLGTLEKQAERAETLDQCRVRALALLEQLKAWGKEAPPESELIGQECVLWVEAYSSSLQLHRTPLSIAPIFNKQREGSARTWIFTSATLAVKQDFSHYTSQMGLLEEKALSWPSPFDYAKQGLLYIPTGMPEPRSFDYTDAVVDAALPVIIASGGRAFLLCTTLRAVKHCAQRLRDEFEKQNLTFSLFVQGESGRTELLEKFRQSGNGILVGSQSFWEGIDVRGEALSLVVIDKLPFAPPDDPVLAARINAMERQGKNGFVHHQLPEAIINLKQGAGRLIRDETDRGVLMLCDPRILSKPYGARVWQSMPPFTRTRELKVVEDFFHSLKTQPEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUT7</accession>
    <name>A0A2S9GUT7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Methyltransferase domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3757</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000022">
        <property type="protein sequence ID" value="PRC91479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91479">
        <property type="protein sequence ID" value="PRC91479"/>
        <property type="gene ID" value="S2091_3757"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="229" mass="26318" checksum="73BE8F0BBB42861C" modified="2018-07-18" version="1">MMTSECDKNAENWEAIYRQKKAGNYLIYPSEHLVSLFFQNKAAITLSGKCLDFGFGSANNSEFLIQQMQELYGIEIAESSLISAKNRLAKYTNFNPENFKLIAKEHDFNHNFFDLIVAWQMLYYNDMANLELTIAKLADYLKPGGILICTLITNNDVKVRHANRVAADTYEIDHRIPHQEGCKVFSPKNKDDFLALFQAFNVIDVGYYERTSFLAENSTSEYYLIAKKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUX3</accession>
    <name>A0A2S9GUX3_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 8">Corrinoid adenosyltransferase</fullName>
            <ecNumber evidence="5 8">2.5.1.17</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Cob(II)alamin adenosyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Cob(II)yrinic acid a,c-diamide adenosyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">S2091_3805</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7 8">Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 8">
            <text>2 ATP + 2 cob(II)alamin + reduced [electron-transfer flavoprotein] = 2 adenosylcob(III)alamin + 3 H(+) + oxidized [electron-transfer flavoprotein] + 2 triphosphate</text>
            <dbReference type="Rhea" id="RHEA:28671"/>
            <dbReference type="Rhea" id="RHEA-COMP:10685"/>
            <dbReference type="Rhea" id="RHEA-COMP:10686"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16304"/>
            <dbReference type="ChEBI" id="CHEBI:18036"/>
            <dbReference type="ChEBI" id="CHEBI:18408"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58307"/>
            <dbReference type="EC" id="2.5.1.17"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>2 ATP + 2 cob(II)yrinate a,c diamide + reduced [electron-transfer flavoprotein] = 2 adenosylcob(III)yrinate a,c-diamide + 3 H(+) + oxidized [electron-transfer flavoprotein] + 2 triphosphate</text>
            <dbReference type="Rhea" id="RHEA:11528"/>
            <dbReference type="Rhea" id="RHEA-COMP:10685"/>
            <dbReference type="Rhea" id="RHEA-COMP:10686"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18036"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58307"/>
            <dbReference type="ChEBI" id="CHEBI:58503"/>
            <dbReference type="ChEBI" id="CHEBI:58537"/>
            <dbReference type="EC" id="2.5.1.17"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 8">Cofactor biosynthesis; adenosylcobalamin biosynthesis; adenosylcobalamin from cob(II)yrinate a,c-diamide: step 2/7.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 8">Belongs to the Cob(I)alamin adenosyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.17" evidence="5 8"/>
    <dbReference type="EMBL" id="PUGF01000022">
        <property type="protein sequence ID" value="PRC91527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91527">
        <property type="protein sequence ID" value="PRC91527"/>
        <property type="gene ID" value="S2091_3805"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00148">
        <property type="reaction ID" value="UER00233"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008817">
        <property type="term" value="F:cob(I)yrinic acid a,c-diamide adenosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009236">
        <property type="term" value="P:cobalamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006779">
        <property type="term" value="P:porphyrin-containing compound biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00561">
        <property type="entry name" value="CobA_CobO_BtuR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003724">
        <property type="entry name" value="CblAdoTrfase_CobA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025826">
        <property type="entry name" value="Co_AT_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12557">
        <property type="entry name" value="Co_AT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02572">
        <property type="entry name" value="CobA_CobO_BtuR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015617">
        <property type="entry name" value="Adensltrnsf_CobA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00708">
        <property type="entry name" value="cobA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0169">Cobalamin biosynthesis</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 8" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Co_AT_N" evidence="10">
        <location>
            <begin position="9"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="10"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR015617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF12557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC91527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="210" mass="23336" checksum="67689439A00E7E8D" modified="2018-07-18" version="1">MSEENTPTSKSTDINERHRVRMERKKEIVDDKIQQAQRKAGVIVITTGNGKGKSSSGFGMVIRAMGNDMKVGVVQFIKGAMSTGEEKFLHRFPDEVSIHAMGEGYTWNTQNRERDMEKAEAAWAKSKEYLSDPSIGLVLLDELNIALKYHYLDVHKVIADLQARPPMQHVVITGRGALPELIAVADTVTEMQEVKHAFKSGIGAQAGVEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GV33</accession>
    <name>A0A2S9GV33_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Bifunctional purine biosynthesis protein PurH</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="8">Phosphoribosylaminoimidazolecarboxamide formyltransferase</fullName>
                <ecNumber evidence="8">2.1.2.3</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="8">AICAR transformylase</fullName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="8">IMP cyclohydrolase</fullName>
                <ecNumber evidence="8">3.5.4.10</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="8">ATIC</fullName>
            </alternativeName>
            <alternativeName>
                <fullName evidence="8">IMP synthase</fullName>
            </alternativeName>
            <alternativeName>
                <fullName evidence="8">Inosinicase</fullName>
            </alternativeName>
        </domain>
    </protein>
    <gene>
        <name evidence="8" type="primary">purH</name>
        <name evidence="10" type="ORF">S2091_3689</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>(6S)-10-formyltetrahydrofolate + 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide = (6S)-5,6,7,8-tetrahydrofolate + 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide</text>
            <dbReference type="Rhea" id="RHEA:22192"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="ChEBI" id="CHEBI:57454"/>
            <dbReference type="ChEBI" id="CHEBI:58467"/>
            <dbReference type="ChEBI" id="CHEBI:58475"/>
            <dbReference type="EC" id="2.1.2.3"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>H2O + IMP = 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide</text>
            <dbReference type="Rhea" id="RHEA:18445"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <dbReference type="ChEBI" id="CHEBI:58467"/>
            <dbReference type="EC" id="3.5.4.10"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Purine metabolism; IMP biosynthesis via de novo pathway; 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide (10-formyl THF route): step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 8">Purine metabolism; IMP biosynthesis via de novo pathway; IMP from 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide: step 1/1.</text>
    </comment>
    <comment type="domain">
        <text evidence="8">The IMP cyclohydrolase activity resides in the N-terminal region.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the PurH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.3" evidence="8"/>
    <dbReference type="EC" id="3.5.4.10" evidence="8"/>
    <dbReference type="EMBL" id="PUGF01000021">
        <property type="protein sequence ID" value="PRC91573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91573">
        <property type="protein sequence ID" value="PRC91573"/>
        <property type="gene ID" value="S2091_3689"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00133"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003937">
        <property type="term" value="F:IMP cyclohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004643">
        <property type="term" value="F:phosphoribosylaminoimidazolecarboxamide formyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00139">
        <property type="entry name" value="PurH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024051">
        <property type="entry name" value="AICAR_Tfase_dup_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011607">
        <property type="entry name" value="MGS-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036914">
        <property type="entry name" value="MGS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002695">
        <property type="entry name" value="PurH-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11692">
        <property type="entry name" value="PTHR11692"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01808">
        <property type="entry name" value="AICARFT_IMPCHas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02142">
        <property type="entry name" value="MGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000414">
        <property type="entry name" value="AICARFT_IMPCHas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00798">
        <property type="entry name" value="AICARFT_IMPCHas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00851">
        <property type="entry name" value="MGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52335">
        <property type="entry name" value="SSF52335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="SSF53927"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00355">
        <property type="entry name" value="purH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51855">
        <property type="entry name" value="MGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 8" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="5 8" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="MGS-like" evidence="9">
        <location>
            <begin position="1"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC91573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="528" mass="56825" checksum="06F128C62C7D3DB2" modified="2018-07-18" version="1">MIKQALISVSDKTGVVEFARALSAMGVQLLSTGGTAKLLAEQGLPVVEVGSYTGFPEMLDGRVKTLHPKVHGGILARRDFPAHMAALEQHNIPTIDMVVVNLYPFQATVAKDNCSLEDAIENIDIGGPTMLRSSAKNHKDVVVICDPLDYKVVLAEMNAQNGTVSYDTKFTLAKKVFAHTAQYDGAITNYLTSLGEDKEHSTRSAYPQTLNLHFEKVQEMRYGENPHQSASFYRDLNVADGALANYVQLQGKELSYNNIADADAAWECVKSFDAVNGPAACVIVKHANPCGVAIAETPLAAYSKAWQTDPTSAFGGIIAFNRELDGAAAEMVAKQFVEVLIAPSFTAEARAIFATKQNVRVLQISLDSAGLAVNKHDYKRVGGGLLVQSPDAKNIGLDDLKIVSKRQPTPEQLQDMLFAWRVAKYVKSNAIVFCGNGMTLGVGAGQMSRVDSARIASIKAKNSGLTLAGSTVASDAFFPFRDGLDVVVDAGATCVIQPGGSMRDQEVIDAADERNVVMMLTGVRHFRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GV40</accession>
    <name>A0A2S9GV40_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3711</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000021">
        <property type="protein sequence ID" value="PRC91595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91595">
        <property type="protein sequence ID" value="PRC91595"/>
        <property type="gene ID" value="S2091_3711"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="128"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="136"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="207" mass="23543" checksum="A65022989C685A62" modified="2018-07-18" version="1">MKISRYFANLKSSYNAELDDLRTDSEGNNVLKARLAKKREQVPQLLMMMQSAPEMVAVAFHGGFFFKNVMVLEALVTREENKFPTWETLKKAIILEPWAQALVNIVLTDPDGEAFLITTAGLEYLNRSSQSRAAHPSNADEDEHSADHEDQDDDLHDHEHDNEHDDDNNDAYLNSDERVADEGETTEYDLDKAGANWLAEQGFDRKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GV41</accession>
    <name>A0A2S9GV41_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3718</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000021">
        <property type="protein sequence ID" value="PRC91602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91602">
        <property type="protein sequence ID" value="PRC91602"/>
        <property type="gene ID" value="S2091_3718"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010281">
        <property type="entry name" value="DUF885"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33361">
        <property type="entry name" value="PTHR33361"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05960">
        <property type="entry name" value="DUF885"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015485986" evidence="1">
        <location>
            <begin position="23"/>
            <end position="595"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="595" mass="66080" checksum="F8372846F8E348D7" modified="2018-07-18" version="1">MRNIKCLLAVSAALVCFNAANAAPDNSASWVDVSNANTNRLIEAQAKFVPEQASSFGLAQYDGLAIDLGPHIDERLIASMQLVRADLKKRQLEEKDARVRQDIDILIASIDNDITSTQLENKYLLPWSDLPQLMFGSMLDLLQEQLPAERRAKALERLQRYVGIYPGSESVTKQAEARFMEKLGKPGLLGPTKERVDKSLTNVPTYIKGIRDLFAKMKIEGAEPTLAAMEKQLNDYAAWERAKVLPVAREDFKLPPELYALSLKQMGINIDPQLLIQRAQVEFMETRSALQQIAPVVAKKLAIDASDYRDVIRAMKKNTIPNDQLEAFYKKVNVTLEEAIRTGKIVEVPNRPMIMRLASDAESAAQPAPHFQPPQLIGNTGEQGQFILPVGNPAAAGKSESYDDFNFPGAAWTLSAHEGRPGHELQFSAMIEHGVSQARSLYAFNSVNVEGWALYAEAEMVPFEPAEGQMIALQLRLLRAARAMLDPMLNLGLITREEAGRILTDEVLISPAMARQELDRYTLNMPAQAGSYFYGYSRLLQLRAETELALGAKFDRFAFNNFLLSQGLLPPDLLAKAVREEFVPAQKAKAVLAKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GV77</accession>
    <name>A0A2S9GV77_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">GGDEF: diguanylate cyclase (GGDEF) domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_3727</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000021">
        <property type="protein sequence ID" value="PRC91611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91611">
        <property type="protein sequence ID" value="PRC91611"/>
        <property type="gene ID" value="S2091_3727"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015709445" evidence="2">
        <location>
            <begin position="29"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="176"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="206"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="235"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="270"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="3">
        <location>
            <begin position="464"/>
            <end position="600"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC91611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="610" mass="68731" checksum="B03CCDC803309168" modified="2018-07-18" version="1">MTRTPFRLSVILAFQFVLLCIAAGNCHAQTTLKEEIFSTYCGAADLSLQPQNIAVIWQPMIDTALLIPPKGRCWMRLSAQNQRSDTNGSAYLILQRSPLIDTVLFDGQGKEITQSTHDRQSELAIEIGRRILFPTAALSNGPLYVRFNSSNPIFQERVINKGFSPLSVGVMEQQRLLMTTIFAAVVLLTSAMFIASFGIALRDLDFGIYSIYTFALGVTLIAWDQVDLPIVGINYGWVWQFGCPISEAMLCWLAIRFGKFDRHSIVVSRILKLVIAFNVLLLLWSMLAKIGVPVMPMPFDRFSYDNWQDVLIGALIMIGSWRGGRRGERDCYLLLLSLTPSMISDFINRIWDPAIAPFLQSSLGYALPHWLNKTIHFNGSLTWLALPMIFCFALARRSLLLHRSLIDERKLLEERVFDRTMELHSAMKELELLATTDSLTGLANRRSMNEWINHEIERSCRFHKPLALCMIDIDHFKNINDTFGHATGDLAIAAIAKTFNETIRKTDIASRYGGEEFLLLMPETDEIEASVVTERLREAIQALQLYSDDNHVFAVTASIGVAFFDHQAAEDTMSKLLNRVDKALYRAKNAGRNQVAFSSSQFSADAAFSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVF2</accession>
    <name>A0A2S9GVF2_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 10">Protein-export membrane protein SecG</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">S2091_3637</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Involved in protein export. Participates in an early event of protein translocation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cell membrane</location>
            <topology evidence="10">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the SecG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000020">
        <property type="protein sequence ID" value="PRC91699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91699">
        <property type="protein sequence ID" value="PRC91699"/>
        <property type="gene ID" value="S2091_3637"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015450">
        <property type="term" value="F:protein-transporting ATPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004692">
        <property type="entry name" value="SecG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34182">
        <property type="entry name" value="PTHR34182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03840">
        <property type="entry name" value="SecG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01651">
        <property type="entry name" value="SECGEXPORT"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00810">
        <property type="entry name" value="secG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 10" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 10" id="KW-0811">Translocation</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="54"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="98"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="98"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU365087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PRC91699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="145" mass="13939" checksum="02EA62C160A95E39" modified="2018-07-18" version="1">MNTIFSLVVAIQVCAALVIIGLVLVQHGKGADMGAAFGSGASGSLFGATGSSSFLSKATGIAATIFFCSTLGLAYIGTRHAAPSGGVMDNLSQQKTTEVAPAASAGSASTAASTSAPTSTAIPAPAPAAATKAASNTGHADQIPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVQ4</accession>
    <name>A0A2S9GVQ4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3549</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000019">
        <property type="protein sequence ID" value="PRC91794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91794">
        <property type="protein sequence ID" value="PRC91794"/>
        <property type="gene ID" value="S2091_3549"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="121"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="158"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="202"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="239"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="265"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="305" mass="32394" checksum="90D4F7742C36244E" modified="2018-07-18" version="1">MDLNNKNVWLVLAGISAFLGGLLHIASLIGGSEWFAFLGAPTWAIESVRNGTWIAPVGGLIITGLMWLCSIYAFSGAGFLPKVPLLRTGLFSIACVCILRGLILVPFVIFNPNLFIPRGTFNIIASLIWLAIGMAFALGVQGLLVAPERFAVQKEKNNYLFLSGLVAILGGLLHVAAIFGGPTWYSFIGAPDGLAQMARLGLLYPVVACLVIAAFLFLCASYAFSAIGLIRRLPFLRTGLTLIAIGLICRGIGFIPLMIVRPSLFAGVCNCVGVDSLLIITSAVCLATGTGYAIGTKKSWGRLEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVX2</accession>
    <name>A0A2S9GVX2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="10">TonB-siderophor: TonB-dependent siderophore receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">S2091_3428</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000018">
        <property type="protein sequence ID" value="PRC91872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91872">
        <property type="protein sequence ID" value="PRC91872"/>
        <property type="gene ID" value="S2091_3428"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015344">
        <property type="term" value="F:siderophore uptake transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0038023">
        <property type="term" value="F:signaling receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039423">
        <property type="entry name" value="TonB-dep_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010105">
        <property type="entry name" value="TonB_sidphr_rcpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32552">
        <property type="entry name" value="PTHR32552"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01783">
        <property type="entry name" value="TonB-siderophor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="3 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 10" id="KW-0675">Receptor</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0798">TonB box</keyword>
    <feature type="domain" description="Plug" evidence="9">
        <location>
            <begin position="87"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="8">
        <location>
            <begin position="271"/>
            <end position="749"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="65"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC91872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="752" mass="82644" checksum="CB533653BFBADD85" modified="2018-07-18" version="1">MHQKLNKYPLALAIETIDFPHEIALIKRRQPPSSFSAGLSISAFMLAASASSWAQTTLPEVTVTTDRSSKETLQTNQTSIGKGTQDIRDIPQSITVMTEKLMDEAKLTTLKEALHYTSGITFAAAENGTDQDIRLRGFPVATTGDLLLDGMRDPSQYDRDAFNYDRIEVMRGSASMLFGRGSTGGVINQVSKKSFLDDHNEIDTTLGTGRYFRLTGDFNIRTGNDSALRMNVMRNTADNKGAEINKYGIAPTFSWGIGHRDEFSVGLFYLNVDNVPMSGIRYLNGTVPDIKPGNFYGTKSDYQRGEATYLSASHKHRFDDGGQLHSQIRSGRFNRSQWSTTASFAKGTTPENLNGATVLTRSGLAPRKDSYTGTYLQSDYSNKYNAFGVKHELIGGVDAAYEKADRFGGWGGVGTNYNKGNTTVGTPNDGRSLPVEPMYRDISNYSFKSFGLYVQDLVQIAPDWKLLGGIRFDSFKGDFDQIAYLNATTNMSNKTTSTSLSDSMFSYRTGVLYQPSATSSYHLSYGTSFNTSADTYQYVTQQTANTPPEKSRNIELGAKLDWMDGNLSTRGALFQTEKYNERTTDSDFAGDAYTLSGKRHSRGMEIDIVGKLTPKTEVYFSYTNIWDASIDKAGSAANAQASVGKRVGLTPKQSAALWLSYQAMPKLRVAGGVHGASENFALSGQTGAAYANARAPGYAVADLMLEYTIDPRWTAQLNVNNAFNRRYGDQLYPGFVVLGAPRTFLLTVATRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWG7</accession>
    <name>A0A2S9GWG7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Radc: DNA repair protein RadC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_3212</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the UPF0758 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000016">
        <property type="protein sequence ID" value="PRC92077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92077">
        <property type="protein sequence ID" value="PRC92077"/>
        <property type="gene ID" value="S2091_3212"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08071">
        <property type="entry name" value="MPN_DUF2466"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037518">
        <property type="entry name" value="MPN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025657">
        <property type="entry name" value="RadC_JAB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010994">
        <property type="entry name" value="RuvA_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001405">
        <property type="entry name" value="UPF0758"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020891">
        <property type="entry name" value="UPF0758_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30471">
        <property type="entry name" value="PTHR30471"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04002">
        <property type="entry name" value="RadC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47781">
        <property type="entry name" value="SSF47781"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00608">
        <property type="entry name" value="radc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50249">
        <property type="entry name" value="MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01302">
        <property type="entry name" value="UPF0758"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="MPN" evidence="7">
        <location>
            <begin position="102"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC92077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="224" mass="24610" checksum="57B9032A2324BB5E" modified="2018-07-18" version="1">MSISNWPEDQRPRERLIKHGPSALSNAELLAVFLRVGVKGKSAVELGNDMLGHFGSLDSLFSASLDSFSLIKGLGPAKFAQLQAVLELAKRALLEDLQEGVTLNSPQAVKNYLQLLIGSKPFESFAVLFLDVKNRLIHSEELFRGSLSHASVYPREVLKRALHHNAAAVILAHNHPSGQCEPSKADITLTDELKKALALVEVKVLDHFIVARNKTYSFAEHGMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWJ4</accession>
    <name>A0A2S9GWJ4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3227</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000016">
        <property type="protein sequence ID" value="PRC92092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92092">
        <property type="protein sequence ID" value="PRC92092"/>
        <property type="gene ID" value="S2091_3227"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="101" mass="11276" checksum="50A7DC1A303D8348" modified="2018-07-18" version="1">MTSTDQIHAQQSPPLITHLAVDTIDAYTQARDIVSDFSAIFEVLDHLALEGLCSDRISRILFRAGYSHATEQLKFLDEKIVDAYQTLDELKADSNHAANTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWN0</accession>
    <name>A0A2S9GWN0_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="14 15">Dihydroxy-acid dehydratase</fullName>
            <shortName evidence="15">DAD</shortName>
            <ecNumber evidence="14 15">4.2.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">ilvD</name>
        <name evidence="17" type="ORF">S2091_3243</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>(2R)-2,3-dihydroxy-3-methylbutanoate = 3-methyl-2-oxobutanoate + H2O</text>
            <dbReference type="Rhea" id="RHEA:24809"/>
            <dbReference type="ChEBI" id="CHEBI:11851"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:49072"/>
            <dbReference type="EC" id="4.2.1.9"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:24810"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>(2R,3R)-2,3-dihydroxy-3-methylpentanoate = (S)-3-methyl-2-oxopentanoate + H2O</text>
            <dbReference type="Rhea" id="RHEA:27694"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:35146"/>
            <dbReference type="ChEBI" id="CHEBI:49258"/>
            <dbReference type="EC" id="4.2.1.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15">
            <name>2Fe-2S cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49601"/>
        </cofactor>
        <text evidence="15">Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 15">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="13 15">Amino-acid biosynthesis; L-isoleucine biosynthesis; L-isoleucine from 2-oxobutanoate: step 3/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="12 15">Amino-acid biosynthesis; L-valine biosynthesis; L-valine from pyruvate: step 3/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="15">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 15">Belongs to the IlvD/Edd family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.9" evidence="14 15"/>
    <dbReference type="EMBL" id="PUGF01000016">
        <property type="protein sequence ID" value="PRC92108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92108">
        <property type="protein sequence ID" value="PRC92108"/>
        <property type="gene ID" value="S2091_3243"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00047">
        <property type="reaction ID" value="UER00057"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00049">
        <property type="reaction ID" value="UER00061"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004160">
        <property type="term" value="F:dihydroxy-acid dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009099">
        <property type="term" value="P:valine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00012">
        <property type="entry name" value="IlvD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042096">
        <property type="entry name" value="Dihydro-acid_dehy_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004404">
        <property type="entry name" value="DihydroxyA_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000581">
        <property type="entry name" value="DiOHA_6PGluconate_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020558">
        <property type="entry name" value="DiOHA_6PGluconate_deHydtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037237">
        <property type="entry name" value="IlvD/EDD_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00920">
        <property type="entry name" value="ILVD_EDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143975">
        <property type="entry name" value="SSF143975"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00110">
        <property type="entry name" value="ilvD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00886">
        <property type="entry name" value="ILVD_EDD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00887">
        <property type="entry name" value="ILVD_EDD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 15" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="3 15" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="10 15" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="7 15" id="KW-0408">Iron</keyword>
    <keyword evidence="8 15" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="9 15" id="KW-0456">Lyase</keyword>
    <keyword evidence="6 15" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="15">
        <location>
            <position position="477"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="54"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="86"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="128"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" description="via carbamate group" evidence="15">
        <location>
            <position position="129"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="451"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-carboxylysine" evidence="15">
        <location>
            <position position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00029304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00029436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00029437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00029490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="PRC92108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="561" mass="59054" checksum="B19DD77112EB7796" modified="2018-07-18" version="1">MSTDSNFNRRSKNITQGVSRSPNRSMYYAMGYEKSDFDKPMVGVANGHSTITPCNSGLQKLADIAIKTLKEVGANPQVFGTPTISDGMSMGTEGMKYSLISREVIADCIETAVNGQWMDGCVVIGGCDKNMPGGMIALARTNVPSIYVYGGTIKPGNWKGRDLTIVSAFEAVGEFTAGRMSQEDFDGIEKNACPSSGSCGGMYTANTMSSSFEALGMSLLYSSTMANPDDEKTGSAAQSARVLMEAVKRDLKPRDIITKKSIENAVAVIMAIGGSTNAVLHYLAIAHAAEIEWTLDDFERVRLQVPVICDLKPSGQYVATDLHKAGGIPQVMKLLLNAGLIHGDCMTITGRTLAEELAGVPDQPSAEHPVIRTIQNALYAKGHLAILKGNLSPEGCVAKISGLKNPVITGPARVFEDESSAMEAILGDKIVPGDVIVLRYLGPKGGPGMPEMLAPTSAIIGKGLGESVGLVTDGRFSGGTWGMVVGHVSPEAFVGGTIALVNEGDSITIDALDQLIQLNVPEAEIAKRRAAWTAPAPRYTRGVLAKYAALTSSASKGAVTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWT1</accession>
    <name>A0A2S9GWT1_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF4124 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_3251</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000016">
        <property type="protein sequence ID" value="PRC92116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92116">
        <property type="protein sequence ID" value="PRC92116"/>
        <property type="gene ID" value="S2091_3251"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025392">
        <property type="entry name" value="DUF4124"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13511">
        <property type="entry name" value="DUF4124"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015629001" description="DUF4124 domain-containing protein" evidence="2">
        <location>
            <begin position="27"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4124" evidence="3">
        <location>
            <begin position="15"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="156"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="169"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC92116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="203" mass="22121" checksum="59FD1D0CFE37B262" modified="2018-07-18" version="1">MKAKTTMTSKLLLSLLLLTLSLTAQAQLYKWVGPDGKVNYSDTPPPKSVTKVETKSFSDSDSGVALPFELAQAAKNMPVTLYSADKCIPCDDSRSYLKQSGIPFSEKTVSSNEDLAKLKQLSGDFQLPLLTIGRSKLKGFNIAVWHTNLTQAGYPDSNKLPPEYQFPTPQPLTSVAVTPKQTDTSVKPGQPEPPARDPNGFQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWY8</accession>
    <name>A0A2S9GWY8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">GGDEF: diguanylate cyclase (GGDEF) domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_3153</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92237">
        <property type="protein sequence ID" value="PRC92237"/>
        <property type="gene ID" value="S2091_3153"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01948">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001633">
        <property type="entry name" value="EAL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035919">
        <property type="entry name" value="EAL_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00563">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00052">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141868">
        <property type="entry name" value="SSF141868"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50883">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="46"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="98"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="122"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="151"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="3">
        <location>
            <begin position="232"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="domain" description="EAL" evidence="2">
        <location>
            <begin position="374"/>
            <end position="628"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC92237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="633" mass="70213" checksum="74A13ABC610BB6FD" modified="2018-07-18" version="1">MPPNTKPSKTIINAGLALRPHRLIQIVSIVLIAISISILLNLLEGNWTTVCILLGISGVLSLAVWQAKSNHIDRAAKIVVATLACSMCFLSFKFEGIHDAAICALPAIMIFAAMFSTRRLFITTLIFIFVILTLMVTANIQGWYINEVKPVTWNSLIDVLAILSATACFVWLLASDLRVALAHLETENDRISDAFSRIDTLAHHDALTGLPNRLLARLRFEQAVELARRSQQHIAVLFLDLDNFKTVNDSLGHAAGDALLCDVAQRLKIAARASDTVSRQGGDEFLIVMAGQADHSAVATVSVKIINSLLAPFHVNGMELLVTCSLGIALYPEDGEDFDTLLKHSDMAMYKAKDSGRNALRFYDVEMNTSVIEHLHLISGIRSALLKHEFKLYYQPQYHLKTGRIIGAEALIRWIHPEQGLIPPIRFIPVAERSGQIHEIGTWVINEACRQAKEWQNAGLSQLVVAINLSPIQFRRDDLEGDVMHALATAQLSASSIELELTESLLIAESSQISSLLSRLRLLGIRLSIDDFGTGYSNLGYLSRFEVERLKIDQSFVRRMMDNSNDQGIVRAIIEMAHSLKLEVVAEGVENSATLTRLIELGCEYGQGFHWSPALPAEQFFKFVKDYQILDGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXQ3</accession>
    <name>A0A2S9GXQ3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">DoxX</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_2868</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DoxX family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92493">
        <property type="protein sequence ID" value="PRC92493"/>
        <property type="gene ID" value="S2091_2868"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032808">
        <property type="entry name" value="DoxX"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07681">
        <property type="entry name" value="DoxX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="18"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="57"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="84"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="117"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC92493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="154" mass="17502" checksum="AC9E93AB35F7E7CE" modified="2018-07-18" version="1">MKKYIDEFPYLTLDQSLVIFRLTLAALFMAHATMRFFEPHYFHDFGDFLAQRSVPFAHAVPYIATAIEMVGGVFLIFNKFSRWVAMSFFGISAGGIIIIHARLGWFVGEWGEGGCEYSVALCVMCLLMAAIDREKQKTIVRPSFDDSQLPLMAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXR5</accession>
    <name>A0A2S9GXR5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NlpC/P60 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2878</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C40 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92503">
        <property type="protein sequence ID" value="PRC92503"/>
        <property type="gene ID" value="S2091_2878"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000064">
        <property type="entry name" value="NLP_P60_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00877">
        <property type="entry name" value="NLPC_P60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="SSF54001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51935">
        <property type="entry name" value="NLPC_P60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NlpC/P60" evidence="2">
        <location>
            <begin position="107"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="234" mass="26777" checksum="9DC8730A90BE253B" modified="2018-07-18" version="1">MYKPSPLQLKKLGNKSYMVRIEPNLWIPATFARAMQLTDILRFPEDGYSNFSPSRKDSLRQSQIESNEVVRVLGHHEQHILIMKSDKVLGWVLQNEVEISPEIKAFDPVTSMKLSTGEFFDLWSGTPYVWGGITRIGIDCSGLAQCYFRDVLDRCIPKNTFDQRRSGTSKDLANISKHDLIFCTRIGGRGTHHVGIYVDGDVWHAHRDHGVIRQSLSDFLVDYQVLEVVNRIKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXS2</accession>
    <name>A0A2S9GXS2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2899</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92524">
        <property type="protein sequence ID" value="PRC92524"/>
        <property type="gene ID" value="S2091_2899"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015443899" evidence="2">
        <location>
            <begin position="23"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="221" mass="24861" checksum="67E222B1B8B17D67" modified="2018-07-18" version="1">MRSMFLASLCLIVFVPFNAAIAQNDQTGSTVNSGNNSQNQASIKRESPFSFTPDEMQDKLMQVLKIPAKELSKEKVEAIFGIKMGNPGEVGPESLHEESTHQRKKSRWYKSYIQVGVDWSFSLGITVGPNSTGFGFRWWNLKNSSNPFALPMCIDLQKISEAIEHTNMGWELFHDPHGTRHANLSRLFTRSAKRFDTVNVEYVDGANCMSAFDFDINTQGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXS5</accession>
    <name>A0A2S9GXS5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Arginase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2883</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the arginase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92508">
        <property type="protein sequence ID" value="PRC92508"/>
        <property type="gene ID" value="S2091_2883"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016813">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006035">
        <property type="entry name" value="Ureohydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023696">
        <property type="entry name" value="Ureohydrolase_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43782">
        <property type="entry name" value="PTHR43782"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00491">
        <property type="entry name" value="Arginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036979">
        <property type="entry name" value="Arginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00116">
        <property type="entry name" value="ARGINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52768">
        <property type="entry name" value="SSF52768"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51409">
        <property type="entry name" value="ARGINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="272" mass="29776" checksum="639D0CDC3B7D6C87" modified="2018-07-18" version="1">MKNHLLVPYLMGQRRDRLSRVRDLDSRAWEVLAIPDLHEVSIPDANEQMRRMGKVYANLANAVVAVVASGAVPVCIAGDCVSTLGMLAGLQQAGKAPDRILWLDAHGDFHTYSTTQTQYIGGMPLAMMVGQSDGRKYSHDTFAALRAAIGVTPYPEQQVILSDARDLDPGEKEALAESGVIRCSIQEVALHLVPGERLYLHFDTDVLDAEADMPALKYHVKEGPTYADITALLQSLRSKNIVAISMSAWHAEQDVDDKTAMACIKLLNEVLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GY35</accession>
    <name>A0A2S9GY35_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2690</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92635">
        <property type="protein sequence ID" value="PRC92635"/>
        <property type="gene ID" value="S2091_2690"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="76" mass="8630" checksum="4568BFBDAE1FC60B" modified="2018-07-18" version="1">MKKFTEQDVIELFNGDQADIFKKVADRLNKGSHTNLFMLLSEEIEAMKSPSAEEMAVEASRINYDRAFFGKNLQAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GY77</accession>
    <name>A0A2S9GY77_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2732</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92677">
        <property type="protein sequence ID" value="PRC92677"/>
        <property type="gene ID" value="S2091_2732"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="115" mass="13315" checksum="C06D6331BE1D8FC8" modified="2018-07-18" version="1">MLQFAENEFYLCELQPDGASRRDIYKIVEQQLGRKPDDYLELPCPPELLYLWNVFIKLSGSRQRDGMGGMSSISYLEMLAYDQLMQFGLTPQDVDMIKLLDDTYLVSARKPVRAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYB3</accession>
    <name>A0A2S9GYB3_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">UDP-glucose 4-epimerase</fullName>
            <ecNumber evidence="3">5.1.3.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Galactowaldenase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">UDP-galactose 4-epimerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_2439</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>UDP-alpha-D-glucose = UDP-alpha-D-galactose</text>
            <dbReference type="Rhea" id="RHEA:22168"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="ChEBI" id="CHEBI:66914"/>
            <dbReference type="EC" id="5.1.3.2"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the polysaccharide synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.1.3.2" evidence="3"/>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92709">
        <property type="protein sequence ID" value="PRC92709"/>
        <property type="gene ID" value="S2091_2439"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003978">
        <property type="term" value="F:UDP-glucose 4-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009103">
        <property type="term" value="P:lipopolysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05237">
        <property type="entry name" value="UDP_invert_4-6DH_SDR_e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013692">
        <property type="entry name" value="CapD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003869">
        <property type="entry name" value="Polysac_CapD-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08485">
        <property type="entry name" value="Polysacc_syn_2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02719">
        <property type="entry name" value="Polysacc_synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Polysacc_synt_2" evidence="7">
        <location>
            <begin position="7"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="domain" description="Polysacc_syn_2C" evidence="8">
        <location>
            <begin position="284"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00018569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00031367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00033067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF08485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC92709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="336" mass="37680" checksum="F9CD6C2300AC6824" modified="2018-07-18" version="1">MFKDKILLITGGTGSFGNAVLQRFLDSDLAEIRIFSRDEKKQEDMRIALKSDKVKFYIGDVRERSSINDAMRGVNYVFHAAALKQVPSCEFYPMEAVRTNVLGAENVMQSAIEHGVERCVVLSTDKAVYPINAMGISKAMMEKVMVAKSRLCDPAKTVLSATRYGNVMASRGSVIPLFLSQLMAGKSLTITDPNMTRFLMSLEESVDLVMYAFEHARPGDIFVQKAPASTVGDLAQALNELLKRENLTKVIGTRHGEKLYESLVSREEMARSEDLGEYYRIPADTRDLNYDKYFIEGQTEIADIDDYTSHNTKRLTVEGVKEVLMQLDIVRESINA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYR6</accession>
    <name>A0A2S9GYR6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Type II secretion system (T2SS), protein M</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">S2091_2281</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the GSP M family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92864">
        <property type="protein sequence ID" value="PRC92864"/>
        <property type="gene ID" value="S2091_2281"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015627">
        <property type="term" value="C:type II protein secretion system complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015628">
        <property type="term" value="P:protein secretion by the type II secretion system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007690">
        <property type="entry name" value="T2SS_GspM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023229">
        <property type="entry name" value="T2SS_M_periplasmic_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04612">
        <property type="entry name" value="T2SSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103054">
        <property type="entry name" value="SSF103054"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="25"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004377"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PRC92864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="167" mass="18613" checksum="8E327E2B9D68ED46" modified="2018-07-18" version="1">MQFKAIFIETFTHFWEARQQRERQFLITATVVFVVTLVYLIAIDPAITGRQELKKSLPILHQQAAAMQQMVQELAAIPSAENRHEVSRELIETALSHNGLKAQTLSVNDGVIRAQFSSTSMSALQTWLLEMQKSSGLFVEEIKITGLEGGLVSVNLTLRQSVTNGSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYS4</accession>
    <name>A0A2S9GYS4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Type II secretion system (T2SS), protein L</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">S2091_2280</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the GSP L family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92863">
        <property type="protein sequence ID" value="PRC92863"/>
        <property type="gene ID" value="S2091_2280"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009276">
        <property type="term" value="C:Gram-negative-bacterium-type cell wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015627">
        <property type="term" value="C:type II protein secretion system complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015628">
        <property type="term" value="P:protein secretion by the type II secretion system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024230">
        <property type="entry name" value="GspL_cyto_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025691">
        <property type="entry name" value="GspL_pp_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007812">
        <property type="entry name" value="T2SS_protein-GspL"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12693">
        <property type="entry name" value="GspL_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05134">
        <property type="entry name" value="T2SSL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015761">
        <property type="entry name" value="Protein_L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="T2SSL" evidence="11">
        <location>
            <begin position="6"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="domain" description="GspL_C" evidence="12">
        <location>
            <begin position="229"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004377"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005318"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF05134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF12693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PRC92863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="379" mass="41465" checksum="F8EEBE3694DE4B8D" modified="2018-07-18" version="1">MREGHSTLAELSTTISKSNVVLLIAASDVTLLELSIPPMPEAKLKLALPNLVEDQLMCDSAECVLLLGVKPLSSTKRTIAVAQRSWLQQLSGSLFALGANRIKALPAQLCLPFKSGQSSVRLAEHAQDLCANLSMRFDVDSGVGMLLEPEQNAQERLSVIAMLTPPGAIALQISGELVGEYKTAIDANPAWAERMTVQGFNWVSTIQAAKTVSFNLMAGLNTAQTNRIQWKIWRWPLVLATLVLLVNIIGLNNEYWSLKREAQALKTGMTQTYKVSFPTETVIPAPLDQMKKHLDLAQRNSGQGGSDDFTLLLSQFGAAWSAMNAAQLPKLVSIEYKDHGLVLQIKGEMPQQALAQELSAKGLILKKNNEEIWQVRNAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZ00</accession>
    <name>A0A2S9GZ00_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 8">DNA-binding transcriptional regulator NtrC</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Nitrogen regulation protein NR(I)</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">ntrC</name>
        <name evidence="11" type="ORF">S2091_2372</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92955">
        <property type="protein sequence ID" value="PRC92955"/>
        <property type="gene ID" value="S2091_2372"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000156">
        <property type="term" value="F:phosphorelay response regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009399">
        <property type="term" value="P:nitrogen fixation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006808">
        <property type="term" value="P:regulation of nitrogen utilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002197">
        <property type="entry name" value="HTH_Fis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002078">
        <property type="entry name" value="Sigma_54_int"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025662">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025943">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010114">
        <property type="entry name" value="Transcript_reg_NtrC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02954">
        <property type="entry name" value="HTH_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00158">
        <property type="entry name" value="Sigma54_activat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01590">
        <property type="entry name" value="HTHFIS"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01818">
        <property type="entry name" value="ntrC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00675">
        <property type="entry name" value="SIGMA54_INTERACT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00676">
        <property type="entry name" value="SIGMA54_INTERACT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50045">
        <property type="entry name" value="SIGMA54_INTERACT_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0010">Activator</keyword>
    <keyword evidence="4 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-0535">Nitrogen fixation</keyword>
    <keyword evidence="3 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0678">Repressor</keyword>
    <keyword evidence="6 8" id="KW-0804">Transcription</keyword>
    <keyword evidence="5 8" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="8" id="KW-0902">Two-component regulatory system</keyword>
    <feature type="domain" description="Response regulatory" evidence="10">
        <location>
            <begin position="3"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma-54 factor interaction" evidence="9">
        <location>
            <begin position="136"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="7">
        <location>
            <position position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00019059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU365013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC92955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="490" mass="54450" checksum="A5489901E3ABD666" modified="2018-07-18" version="1">MKPIWLVDDDESIRWVLEKALARQNLVTRSFSNARDALAALEHEAPQVLVSDIRMHGISGLTLLQKVKEVHPGLPVIVMTAFSDLDSAVAAFQGGAFDYLAKPFDLDKAVELIRRALEESLREISVEQLSSETPEILGQAAAMQDVFRAIGRLAQSNVTVLITGESGTGKELVARALHKHSPRSQQPMISLNTAAIPKDLLESELFGHERGAFTGAQTARRGRFEQAEGGTLFLDEIGDMPFDLQTRLLRVLSDGHFYRVGGHQPIKSNVRVIAATHQNLEHRVQQGLFREDLYHRLNVIRLRIPSLRERREDIPILTRHFLMQSALQLGVESKRLSESAMQFLSQLTLPGNVRQLENLCNWIVVMAPGQTVEIKDLPPELLERAGVSVPHQQSPDIQAAVNAIAPLVDATDHTNLPANWQSLLESEAAAMLEVNQPDVMGNLSRQFETILIKSALKFTHGRKNEAAIRLGIGRNTITRKLAELDIDSKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZ05</accession>
    <name>A0A2S9GZ05_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_2381</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92964">
        <property type="protein sequence ID" value="PRC92964"/>
        <property type="gene ID" value="S2091_2381"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016279">
        <property type="term" value="F:protein-lysine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008176">
        <property type="term" value="F:tRNA (guanine-N7-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026170">
        <property type="entry name" value="FAM173A/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003358">
        <property type="entry name" value="tRNA_(Gua-N-7)_MeTrfase_Trmb"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13610">
        <property type="entry name" value="PTHR13610"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02390">
        <property type="entry name" value="Methyltransf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="1 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="16"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="49"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="77"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC92964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="263" mass="29800" checksum="C82311AEAFD71EA0" modified="2018-07-18" version="1">MAKTHLLRQFNKTPPAIVALLIQIASLSFIALVLTVLWQVFKVKLSLPVTLLFHAALTLLLTRCFNLAWWWCVMQPLLPLAIVAMLALALPPFLYFLIFSFLLFFYWSTFRTQVPYFPSTPKVWATVEKLLPQKRPISFVDIGSGLGGLVLYLAKRNPESQFAGVEIAPLPWLLSYLRTLGKRKSPQFLRANYEALNFSDFDVIFAYLSPAAMPGLWAKAKQEMQAGSLLISYEFPIVGVDADQIICPENSRINGVKVYLWIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZ10</accession>
    <name>A0A2S9GZ10_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">RnfB: electron transport complex, RnfABCDGE type, B subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_2355</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92938">
        <property type="protein sequence ID" value="PRC92938"/>
        <property type="gene ID" value="S2091_2355"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007202">
        <property type="entry name" value="4Fe-4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010207">
        <property type="entry name" value="Elect_transpt_cplx_RnfB/RsxB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016463">
        <property type="entry name" value="RnfB/RsxB_Proteobac"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42859:SF3">
        <property type="entry name" value="PTHR42859:SF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04060">
        <property type="entry name" value="FeS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01944">
        <property type="entry name" value="rnfB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51656">
        <property type="entry name" value="4FE4S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4Fe-4S" evidence="6">
        <location>
            <begin position="8"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="5">
        <location>
            <begin position="83"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="5">
        <location>
            <begin position="113"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC92938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="227" mass="24291" checksum="02B9C2F09C0DDDD4" modified="2018-07-18" version="1">MPSLTPSTSATLADQIEDLLPQTQCTKCGFPACRPYAEAIASGAALYNQCPPGGDQGIARLAQLLQQPILPLNVTHGVEHPRAVAVIDEAICIGCTLCIQACPVDAIVGAAKQMHSVIIDKCTGCDLCLPPCPVDCISMVNVTGEQTGWNAWSAEQANAARARHDFRITRLEREKQENDARLLAKASEKLRITQAEIATTPEQAIEQARKKAIINAAIARAMANKPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZ73</accession>
    <name>A0A2S9GZ73_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Cytidylate kinase</fullName>
            <shortName evidence="8">CK</shortName>
            <ecNumber evidence="8">2.7.4.25</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Cytidine monophosphate kinase</fullName>
            <shortName evidence="8">CMP kinase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">cmk</name>
        <name evidence="10" type="ORF">S2091_2424</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>ATP + CMP = ADP + CDP</text>
            <dbReference type="Rhea" id="RHEA:11600"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58069"/>
            <dbReference type="ChEBI" id="CHEBI:60377"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.25"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 8">
            <text>ATP + dCMP = ADP + dCDP</text>
            <dbReference type="Rhea" id="RHEA:25094"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57566"/>
            <dbReference type="ChEBI" id="CHEBI:58593"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.25"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the cytidylate kinase family. Type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.25" evidence="8"/>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC93007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93007">
        <property type="protein sequence ID" value="PRC93007"/>
        <property type="gene ID" value="S2091_2424"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036430">
        <property type="term" value="F:CMP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036431">
        <property type="term" value="F:dCMP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006220">
        <property type="term" value="P:pyrimidine nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02020">
        <property type="entry name" value="CMPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00238">
        <property type="entry name" value="Cytidyl_kinase_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003136">
        <property type="entry name" value="Cytidylate_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011994">
        <property type="entry name" value="Cytidylate_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02224">
        <property type="entry name" value="Cytidylate_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00017">
        <property type="entry name" value="cmk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Cytidylate_kin" evidence="9">
        <location>
            <begin position="27"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="31"/>
            <end position="39"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009427"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC93007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="244" mass="26379" checksum="5B3A9981FE33CE4E" modified="2018-07-18" version="1">MTQYCLYKKIRIAILFLKNSQMTNPIITIDGPTASGKGTVAQLVAQALQFHYLDSGALYRLTALSALTQKLALDDELAIATIASQLPCRFEGEQIWLGDVEVGNTIRAEEIGNAASKIAVLPAVREALLQLQKSFSKAPGLIADGRDMGTVVFPDASLKIYLTASVAARAERRFKQLISKGFSASMQDLMQDLTERDARDQNRSAAPLKPAQGAYILDTSALTVDQAVAEVLQQYASLSVKSSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZ94</accession>
    <name>A0A2S9GZ94_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Phosphate ABC transporter, ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_2113</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93027">
        <property type="protein sequence ID" value="PRC93027"/>
        <property type="gene ID" value="S2091_2113"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015415">
        <property type="term" value="F:ATPase-coupled phosphate ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005315">
        <property type="term" value="F:inorganic phosphate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03260">
        <property type="entry name" value="ABC_PstB_phosphate_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015850">
        <property type="entry name" value="ABC_transpr_PstB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005670">
        <property type="entry name" value="Phosp_transpt1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43423">
        <property type="entry name" value="PTHR43423"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43423:SF3">
        <property type="entry name" value="PTHR43423:SF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00972">
        <property type="entry name" value="3a0107s01c2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 7 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-0592">Phosphate transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-1278">Translocase</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="8">
        <location>
            <begin position="17"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="49"/>
            <end position="56"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC93027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="263" mass="29195" checksum="414DA8D0BAD3AFDC" modified="2018-07-18" version="1">MPSSAHSIAHETLPSAIQISGLNFFYGATQSLKNINLSIKDKKVTAFIGPSGCGKSTLLRTLNRMYDLYPGQRAEGNIIYNNKNILDADQDINMLRAKIGMVFQKPTPFPMSIYDNIAFGVRLYENLSKGEMNERVEWALNKAALWSEVKDKLSKSGLSLSGGQQQRLCIARGVAVKPDVLLLDEPTSALDPISTAKIEELINELKQDYTIAIVTHNMQQAARCSDYTAYMYLGELVEAGVTDQVFMNPVKKETQDYITGRFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZC4</accession>
    <name>A0A2S9GZC4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2175</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93089">
        <property type="protein sequence ID" value="PRC93089"/>
        <property type="gene ID" value="S2091_2175"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014915">
        <property type="entry name" value="Phage_TLS_TfmB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08809">
        <property type="entry name" value="DUF1799"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="92" mass="10065" checksum="918DC8666A678BE3" modified="2018-07-18" version="1">MPPSESALSALGLTLAEAHPDVEVWPDNVQTVNCFIALSTQWKVGMNGVTGLDYAAVLLVMDLFEVDDKKEVFSGLQMMEVEALKFMRSISS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZF9</accession>
    <name>A0A2S9GZF9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2208</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93122">
        <property type="protein sequence ID" value="PRC93122"/>
        <property type="gene ID" value="S2091_2208"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="9"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="310" mass="34258" checksum="321D20C315C199E0" modified="2018-07-18" version="1">MLMLSKHLPSTRTLQCFLAVAQELNFRRAAELLNMSQPPLSRQIKALEDMLRVQLIHRDTHRVSLTTAGEVFKEEAYKFLMGLDLAIAGVKEHFHDVCADVVRIGLTSVINYRLIPQLNALVTDPAFTGGRPLERAWSKHLVERVRSGALDIAIVGDIVTLTADLTVEIVGHEPMIVVLPASHPAVEKTEVDLAELGGTPLFWSSRSDNPAFYDKCERIFKGLGYTAPRRLEPKDFTILLASVAAGEGVALCPQSMQATSHIGVVYRVLQPKLARRLSIDMQVISRASEARPAVRLKVETIRAILADKPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZG6</accession>
    <name>A0A2S9GZG6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative periplasmic or secreted lipoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_2184</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HicA mRNA interferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93098">
        <property type="protein sequence ID" value="PRC93098"/>
        <property type="gene ID" value="S2091_2184"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.920.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012933">
        <property type="entry name" value="HicA_mRNA_interferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038570">
        <property type="entry name" value="HicA_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07927">
        <property type="entry name" value="HicA_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-1277">Toxin-antitoxin system</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006620"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC93098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="73" mass="8497" checksum="A065375783596F55" modified="2018-07-18" version="1">MCIDVYIYYMNSANLIKKLKQDGWYLAHTVGSHNQFKHPTKPGKVTVPHPRKDIQIGTLKSIFKQAGWPWKQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZG9</accession>
    <name>A0A2S9GZG9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GGDEF: diguanylate cyclase (GGDEF) domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2218</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93132">
        <property type="protein sequence ID" value="PRC93132"/>
        <property type="gene ID" value="S2091_2218"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GGDEF" evidence="1">
        <location>
            <begin position="193"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="341" mass="39132" checksum="29141F3D77F2541C" modified="2018-07-18" version="1">MTRSTDSKLLLSLTKLIEKPEIKAFQCSLIQTLNDIISADSITLYEMHTLKKLSKAQAEDFLVRVGYDDRLEKDLPAPMRFSDEAQFLMAYERRDVVIEQIGDQENSLFRCIYPILGIKGVTEFLAIDCKKLIKQEQELATRFIGFYRNYLALLNDNQRDHLTGLLNRKSFDDKMMQIIISLGTGSKRNADKAQYCLALFDIDHFKRVNDTYGHLVGDEVLLHFSQCISETFREYDLLFRVGGEEFVAVIRNVNAKTAEFIMERFRHVIEAYHFPQVGHVTVSIGSTFIAPSDLPVTIMDRADKALYYAKEHGRNQSVIFEQLVASGKLQVDITESDIDLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZJ5</accession>
    <name>A0A2S9GZJ5_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Histidine kinase</fullName>
            <ecNumber evidence="3">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">S2091_2214</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="3"/>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93128">
        <property type="protein sequence ID" value="PRC93128"/>
        <property type="gene ID" value="S2091_2214"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036641">
        <property type="entry name" value="HPT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013655">
        <property type="entry name" value="PAS_fold_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008207">
        <property type="entry name" value="Sig_transdc_His_kin_Hpt_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08447">
        <property type="entry name" value="PAS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13188">
        <property type="entry name" value="PAS_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47226">
        <property type="entry name" value="SSF47226"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50894">
        <property type="entry name" value="HPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 7" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="16"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="43"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="80"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="106"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="141"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="172"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="204"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="11">
        <location>
            <begin position="287"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="12">
        <location>
            <begin position="343"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="11">
        <location>
            <begin position="401"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="12">
        <location>
            <begin position="473"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="11">
        <location>
            <begin position="529"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="12">
        <location>
            <begin position="599"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="11">
        <location>
            <begin position="657"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="12">
        <location>
            <begin position="727"/>
            <end position="781"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="11">
        <location>
            <begin position="930"/>
            <end position="1002"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="12">
        <location>
            <begin position="1006"/>
            <end position="1059"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="9">
        <location>
            <begin position="1077"/>
            <end position="1298"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="10">
        <location>
            <begin position="1342"/>
            <end position="1460"/>
        </location>
    </feature>
    <feature type="domain" description="HPt" evidence="13">
        <location>
            <begin position="1508"/>
            <end position="1609"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="7">
        <location>
            <position position="1393"/>
        </location>
    </feature>
    <feature type="modified residue" description="Phosphohistidine" evidence="6">
        <location>
            <position position="1547"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="PRC93128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="1695" mass="188231" checksum="5F4C975513475CDA" modified="2018-07-18" version="1">MKILIPISEYQTHRTLLLGTFGLGIAALLLNSILSLYVGDQTLFINIAWYTGLGISGALFAAIAAYLLLRLDVLKEGSSFNIQIAVALLVMGYLDALHSLQPAGSVFILLHGLSDALGGLLFAAILLPSVLLENKLLRKNLGIFILISIVLLSIAVILFPHRFPEIALGGDLTALLNVGGGCLFLAASVKLLVCFYNNKKSADLYLCLQCVIFGLSAILIEYSTPWNLQWWILHGVRMIGYSAGLLLINSMLNLTMALKTDLDSRLNKKLIRDSDALLATLNDHAIISITDRAGHIIEVNDAFCTISGYSRQELLGKNHRIINSGVQDTAFWRAMWKTISENKSWRGEVCNKDKNNTLYWVDLLIAPFVDEHGQIEKYSAIHTDITASKNATLMLEGTLRDSKALQSTLNMHSIISIANRAGNIIDVNDAFCKISGYSRQELIGKNHRIINSGLQDTAFWMAMWNDISKGIPWHGEVCNRTKKGSLYWVDTVIAPIVDQNGRIEKYISIFNDISASKISALNFESVLRDSTALLSTLNLHSIISIANRAGNIIQVNDAFCRISGYSRQELMGKNHRIVNSGVQSADFWTTMWNSISNGTPWRGEVCNRAKDGSLYWVDTVIAPFVDKDGLIEKYISIRTDISASKNAALNLENALRDSSALLSTLNLHAIVSIANRAGTITEINDAFCKISGYSRQELLGQNHRIVNSGTHPPEFWHDMWRTISVGKPWRGQVCNCAKNGSCYWVDTFIAPFMDEFGQIEKYISIRTDITASKLAEEALRWNESLLQMMSNSSPLAFLVVDIRSDKILYFNLRFCTIWGIEHLADAMRRGELKHNDIAPDCLAVVADPISYTESCWPLQDEYNQIVIEDEILFKNDRVVRRFSTQIRDSADTYFGRFYIFEEVTESKRVERALSSATESEKNALNALRISEERIKFALEGSGDGVWDWDIKQGKVQLSKRWKEMLGYQESDIGDDISEWSSRLHPDDMQRVMADVQKNLDNKSGSFSNEHRMRCKDGQYLWVLDRGMVVQRDSQGAPLRMVGTHTDITTQKQAEDALKQASETALAASLAKSQFLANMSHELRTPMNTVLGMLTLLRKTELSSAQTDYAVKSDTAARSLLDLLNEILDFSKIEAGKMSLDCHSFSLEQLMLNLSDILANSVGEKPLEVMFDIDPTIPGNLFGDAMRLQQVLVNLSSNAIKFTERGQVVVSVSVVRQNSAKVTLKFCVLDSGIGIAFKNQTDIFKGFIQAEASTTRRFGGTGLGLAISQHFVELMGGKIELESSLGHGSRFYFSISLPIINNVDVPEQNQTAPHRRFDVRSNHKQTSPATLTNNTVKRLQGMRVLVAEDNLNNQQVVRELLECEGAIIQIANNGQEVIYAITEAHIPFDLVLMDLQMPVMDGFTATTKIRINLGMQNLPIIAMTANAMASDREACLAAGMNNHVGKPFDLNHLVNILLKHTGRQETVDVEMTQKISIFTSKQVFTKPAIDAAAAANVDLTTAFNRIGNKSDVYLRMLRTFMSDVTLMPEKFHRHLIAGEYNQLRSAFHTLKGLTGALGINSLMTAAGYAELQFGGTLSVSEAESIVKQVCNAISSCSSNLAMLLKALQAMQNETDAVTKRMAGVPKKLSSNELISVLQTMSERLKNSDMAALESMNLLRKNANYGELLSPIDEAINALNFEKAFQLCTSLLENLSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZK1</accession>
    <name>A0A2S9GZK1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Sporulation related domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_2248</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93162">
        <property type="protein sequence ID" value="PRC93162"/>
        <property type="gene ID" value="S2091_2248"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042834">
        <property type="term" value="F:peptidoglycan binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1070">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007730">
        <property type="entry name" value="SPOR-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036680">
        <property type="entry name" value="SPOR-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05036">
        <property type="entry name" value="SPOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110997">
        <property type="entry name" value="SSF110997"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51724">
        <property type="entry name" value="SPOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="60"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="domain" description="SPOR" evidence="3">
        <location>
            <begin position="232"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="117"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="152"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="158"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC93162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="310" mass="32696" checksum="C94AA66370485481" modified="2018-07-18" version="1">MSLFSIFSKKQPEVTSVAEALAGTADATPAKSKSRKSDTRHTDAQNEQLVPEKKRARRRLIGAIAMVLAVVIGLPMVLDSEPKPLNKNIVIQIPSKDATVASLDPKEEIVQNGLQVDTPIPAPTAPKQPSVPPVAKAAPDTRTITPVTTVAEAAPKTSKPEPKIETKAEAKVETAHSSEMVAKKEAAAKPKAESKADFKADPKPSDSHVTSADESARAMAILGGADTSAKATAVTSRIVVQVGAFATQEKVNELQSKLTSAGFKSFTQKVATDSGDKIRVRIGPFSDKDAADKVKTQLEKLGLTGKLVPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZR3</accession>
    <name>A0A2S9GZR3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_1963</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the LemA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93225">
        <property type="protein sequence ID" value="PRC93225"/>
        <property type="gene ID" value="S2091_1963"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1440.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023353">
        <property type="entry name" value="LemA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007156">
        <property type="entry name" value="MamQ_LemA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34478">
        <property type="entry name" value="PTHR34478"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04011">
        <property type="entry name" value="LemA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140478">
        <property type="entry name" value="SSF140478"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC93225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="181" mass="20302" checksum="85DC4AB4A6379A41" modified="2018-07-18" version="1">MEHWTWIVGAVVVAIIAIGLFNSLTGKKNQVEFAFASVDVQLKKRFDLIPNLVASCEKYMGYEEKVLKDLTETRTKAITCSNDEKIALDGKISSQLRSVFAHAENYPDLKAVETFTLLQMSLNEVEEQLSASRRAFNAAVTEYNNAVQMFPSSIAAKLMGYQTRAWFEAAPVERDVVKVWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZR6</accession>
    <name>A0A2S9GZR6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Thioredoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1945</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93207">
        <property type="protein sequence ID" value="PRC93207"/>
        <property type="gene ID" value="S2091_1945"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03019">
        <property type="entry name" value="DsbA_DsbA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023205">
        <property type="entry name" value="DsbA/DsbL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012336">
        <property type="entry name" value="Thioredoxin-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13462">
        <property type="entry name" value="Thioredoxin_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015393050" evidence="1">
        <location>
            <begin position="21"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin-like_fold" evidence="2">
        <location>
            <begin position="46"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="220" mass="24692" checksum="20A1FE2203C5D454" modified="2018-07-18" version="1">MRAISFVCTSFLFIANLALATPTMPINGAEYTTLATPQPVTSIGKKIEVIEFFMYHCPACNTLEPALLDWVKKQGANVEFKRIHVPHNGLNDAEAHLFLTLEAMKLEDTMHSKVLNTWHVEHHQLLRDEDNLEWAVKNGLDKEKFLGFYNSFSVISKLHNLKNVMANYHVDSTPTIVVDGRYLTSMASVDESNKDLEHVALDKATLQVVDALVAQARASK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZS1</accession>
    <name>A0A2S9GZS1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ergothioneine biosynthesis protein EgtB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1938</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93200">
        <property type="protein sequence ID" value="PRC93200"/>
        <property type="gene ID" value="S2091_1938"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052699">
        <property type="term" value="P:ergothioneine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024775">
        <property type="entry name" value="DinB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017806">
        <property type="entry name" value="EgtB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005532">
        <property type="entry name" value="SUMF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042095">
        <property type="entry name" value="SUMF_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12867">
        <property type="entry name" value="DinB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03781">
        <property type="entry name" value="FGE-sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="SSF56436"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03440">
        <property type="entry name" value="egtB_TIGR03440"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DinB_2" evidence="2">
        <location>
            <begin position="32"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="domain" description="FGE-sulfatase" evidence="1">
        <location>
            <begin position="190"/>
            <end position="443"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="446" mass="51133" checksum="2F787456946EFA43" modified="2018-07-18" version="1">MNVSYTKNQQFFSSKRVDGGVASRQFAETYQSIRQHSINLTVSLSVEDMAVQSMPEASPIKWHLAQTTWFFEKYLLARFVKDYLPFHPAFTMLFNPSSGMNLPRGQRSVITRPTLTLVRTYRTHVDNAVMALIKNMPDEAYPILELGLQREQQTQELMLTDIKHLLGSNPFHPTYINKPLAPAEKVATLKMLELRGGQADIGHPGLTFCFENELPKHRVFLNPFAIADRKITNGEYLAFINAGGYSETRWWLEEGAEWRQREHIKAPLYWRMIDDIWHEYTLHGLMPLDLNRPVCHVSYFEAEAFARFSGARLPTEFEWEFAANSIIPELPGLPGLPTLTDAPVDANKQMEELILHPKGASSATGLKQFFTDTWEWTSSSYAPYPAVKLKNDAAVDHYERQMVNQYVLRGGSVATPPAHSRITYRNFYPTQTRWQFTGIRLARSII</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZV2</accession>
    <name>A0A2S9GZV2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1968</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93230">
        <property type="protein sequence ID" value="PRC93230"/>
        <property type="gene ID" value="S2091_1968"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002818">
        <property type="entry name" value="DJ-1/PfpI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01965">
        <property type="entry name" value="DJ-1_PfpI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="1">
        <location>
            <begin position="215"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="318" mass="34876" checksum="A877F611B0660AF9" modified="2018-07-18" version="1">MKKHLVVALAYDGLCTFEFGCTVELFALKRPELDVDWYEFAICAAETGPIRAAGGFTLEVPHSLALLDSAATIIIPGWRDADELPAAALLDKIRAAYERGARLCSICSGVFVLAAAGVLNGKRATTHWRYAERLTQRYPAIKVQSDALYVDEGQIITSAGSAAGLDMLLHLVRRDYGAKIGNQVAQRLVVAPHREGGQAQFVPRPMAFDEAGKLAKLIDWLRANLAQPHTVKSIAAQSLMSPRTLQRQFQEATGLGPIEWLIVERVAVAKDLLESPHIPLVHVAELAGFGSEESLRRHFRRLVATSPGAYRQRFSNEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H006</accession>
    <name>A0A2S9H006_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2016</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DinB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93278">
        <property type="protein sequence ID" value="PRC93278"/>
        <property type="gene ID" value="S2091_2016"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007837">
        <property type="entry name" value="DinB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034660">
        <property type="entry name" value="DinB/YfiT-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37302">
        <property type="entry name" value="PTHR37302"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05163">
        <property type="entry name" value="DinB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109854">
        <property type="entry name" value="SSF109854"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="176" mass="19955" checksum="54E650F6AE22CA1C" modified="2018-07-18" version="1">MRENLVLFATYNAEMNLRNFHAAQKLSAEELLQDRGAFFGSIMGTLNHLIAADTIWLQRIAHHPSQFSSLLAIQDSPKPTGLNQNRFTDLASWFEHRLSLDQIIKQLVLEITEADLESILHYTRTDGVASNKRLKDVLQHFFNHQTHHRGQISTLLFQAGVDVGVTDLLSLVPNVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H013</accession>
    <name>A0A2S9H013_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2062</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93324">
        <property type="protein sequence ID" value="PRC93324"/>
        <property type="gene ID" value="S2091_2062"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="310" mass="33236" checksum="ECF6819D1700824D" modified="2018-07-18" version="1">MELRQLRYFVAIVDHGSLSRAARVLHIVQPALTQQLQLLEQELGAQLLHRSAQGMSATDAGKLFYEHAQAILKQVGDAKSAVAQSALRPTGTVALGIPQSVSGALALPLLMAVREKYPEISLQLTEELSGNLIEQLKSGRINLAVLFDDGQLAPFIVKPMIEEQMMYITCANSRFAHLGTSIDLAAALQVPLILPGYQHGVRPRIENLVRHAGLAIGDVIDINSVAILKSALLADMGATILPVAPLLSEIERGEMIALPIADSHISRTVVLCASKNIPLTNAASAVERLVLEVAQTLCDSGRWLGASSLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0A3</accession>
    <name>A0A2S9H0A3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_1801</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPF0324 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93414">
        <property type="protein sequence ID" value="PRC93414"/>
        <property type="gene ID" value="S2091_1801"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018383">
        <property type="entry name" value="UPF0324_pro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30106">
        <property type="entry name" value="PTHR30106"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03601">
        <property type="entry name" value="Cons_hypoth698"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="32"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="71"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="96"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="126"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="159"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="186"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="220"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="250"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="280"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="309"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC93414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="334" mass="35245" checksum="F4C7745276897790" modified="2018-07-18" version="1">MKAKAKKLVPGLILCTLVTLSAYYIEYLEASFFQRAWLESLVIAILLGSFIRSVYQLDHQFDAGINFSAKMLLEIAVVLLGVSVSASSILENGPNLILGIAATVAIAIAASYTIGRLVGLPKKMAILIACGNSICGNSAIAAVAPVIEADSNDVASSIAFTAVLGVVVVLILPLMIPLLSLSQLQYGIFAGLTVYAVPQVLAATSSVSLISSHIGTLVKLVRVLMLGPVVLILSLIGKKEDGTRPALSQMVPWFIVGFLALMMFRSFGLVPEALINPAHTTGNFFTIMSMAALGLGVDIRSVARAGSRVASVVVLSLLILFVISFILIRLLGIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0C6</accession>
    <name>A0A2S9H0C6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Plasmid stabilization system protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1822</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93435">
        <property type="protein sequence ID" value="PRC93435"/>
        <property type="gene ID" value="S2091_1822"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2310.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007712">
        <property type="entry name" value="RelE/ParE_toxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035093">
        <property type="entry name" value="RelE/ParE_toxin_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05016">
        <property type="entry name" value="ParE_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-1277">Toxin-antitoxin system</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="94" mass="10642" checksum="5491EFF2D99963F5" modified="2018-07-18" version="1">MKRVKRTQTYLDDLNAIEAHITVQDSPQAAADLWLHIDGQVDLLADPNHPRRKGLVVPDAIELVAHPNYLVILDEDETTVAVLNVLHVKRKHPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0F7</accession>
    <name>A0A2S9H0F7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1848</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93461">
        <property type="protein sequence ID" value="PRC93461"/>
        <property type="gene ID" value="S2091_1848"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1380.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009045">
        <property type="entry name" value="Hedgehog_sig/DD-Pept_Zn-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55166">
        <property type="entry name" value="SSF55166"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="175" mass="19494" checksum="565BC624E38763F5" modified="2018-07-18" version="1">MASIGSDPPPPSSDPIPQVVITPKVYAQDLKKLPQNPEESGYYTYGTPTLGRGQYGNSRALSTLFSIESRWEYNHTNRFGVGNISLKYGGPFEPHVSHQDGGEMDVRALRKDGLEAPVSWQDSQYDRAATKELIKTFKDSGNVNKIFFNDPAMPGVQPLEGHDNHFHVEFKQNAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0J4</accession>
    <name>A0A2S9H0J4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1892</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93505">
        <property type="protein sequence ID" value="PRC93505"/>
        <property type="gene ID" value="S2091_1892"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="45" mass="5133" checksum="1CC6415E5E0919AC" modified="2018-07-18" version="1">MNDGGRTRFHSWRISPLNEAFAALSICDQIPKRARQLAPKSNHQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0M9</accession>
    <name>A0A2S9H0M9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">PEP-CTERM protein-sorting domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_1905</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93518">
        <property type="protein sequence ID" value="PRC93518"/>
        <property type="gene ID" value="S2091_1905"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037524">
        <property type="entry name" value="PA14/GLEYA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011658">
        <property type="entry name" value="PA14_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013424">
        <property type="entry name" value="PEP_exosort_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07691">
        <property type="entry name" value="PA14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07589">
        <property type="entry name" value="PEP-CTERM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00758">
        <property type="entry name" value="PA14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02595">
        <property type="entry name" value="PEP_exosort"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51820">
        <property type="entry name" value="PA14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015771161" evidence="2">
        <location>
            <begin position="27"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="232"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="domain" description="PA14" evidence="3">
        <location>
            <begin position="79"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC93518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="257" mass="26802" checksum="656DDC8B3064B6F1" modified="2018-07-18" version="1">MNIKNLAKFSIIGLALVVTQISAVNANPLTANITYFRISDSDPDANKLCCTDATPEVTNNLGPDGLPMLLSTYTGITPHDTNGADELTYWSPNFNPNVSQTGTGTINIPFNNSAMYNPNGTGFYDGNGNGYLSAVISATLIAPTAETISFTVASDDNAFVFLDGQVVCNNGGVHGAQTVGCTSGTIGAGNHSLEVFYDDLNQTGAVLDFNVITEGITTTPISFDPAPVPEPASLALLAIGLLSLFGVGVSRRVKCRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0P9</accession>
    <name>A0A2S9H0P9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="11">EamA-like transporter family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">S2091_1566</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93565">
        <property type="protein sequence ID" value="PRC93565"/>
        <property type="gene ID" value="S2091_1566"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009245">
        <property type="term" value="P:lipid A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009103">
        <property type="term" value="P:lipopolysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042221">
        <property type="term" value="P:response to chemical"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000390">
        <property type="entry name" value="Small_drug/metabolite_transptr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30561">
        <property type="entry name" value="PTHR30561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-0441">Lipid A biosynthesis</keyword>
    <keyword evidence="3" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="6" id="KW-0448">Lipopolysaccharide biosynthesis</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="7"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="44"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="80"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="105"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="10">
        <location>
            <begin position="52"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC93565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="124" mass="13802" checksum="7A5245B1A465B951" modified="2018-07-18" version="1">MARPSDYIYILATIGFTVYGQLILKWRISHYGPLPMALLEKLKFLTLLLLDPAIFSGFFAGFIASLAWMSAMTKFDLSHAYPFMSLNFVVVLLLSGWFLNEPITLQKTLGILLIVVGTVVAARG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0S8</accession>
    <name>A0A2S9H0S8_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">DNA mismatch repair protein MutL</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">mutL</name>
        <name evidence="8" type="ORF">S2091_1582</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the DNA mismatch repair MutL/HexB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93581">
        <property type="protein sequence ID" value="PRC93581"/>
        <property type="gene ID" value="S2091_1582"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032300">
        <property type="term" value="C:mismatch repair complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030983">
        <property type="term" value="F:mismatched DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1540.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00149">
        <property type="entry name" value="DNA_mis_repair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014762">
        <property type="entry name" value="DNA_mismatch_repair_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020667">
        <property type="entry name" value="DNA_mismatch_repair_MutL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002099">
        <property type="entry name" value="DNA_mismatch_repair_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013507">
        <property type="entry name" value="DNA_mismatch_S5_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038973">
        <property type="entry name" value="MutL/Mlh/Pms"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014790">
        <property type="entry name" value="MutL_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042120">
        <property type="entry name" value="MutL_C_dimsub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042121">
        <property type="entry name" value="MutL_C_regsub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037198">
        <property type="entry name" value="MutL_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10073">
        <property type="entry name" value="PTHR10073"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01119">
        <property type="entry name" value="DNA_mis_repair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08676">
        <property type="entry name" value="MutL_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01340">
        <property type="entry name" value="DNA_mis_repair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00853">
        <property type="entry name" value="MutL_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118116">
        <property type="entry name" value="SSF118116"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00585">
        <property type="entry name" value="mutl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00058">
        <property type="entry name" value="DNA_MISMATCH_REPAIR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0227">DNA damage</keyword>
    <keyword evidence="4 5" id="KW-0234">DNA repair</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA_mis_repair" evidence="7">
        <location>
            <begin position="210"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="domain" description="MutL_C" evidence="6">
        <location>
            <begin position="432"/>
            <end position="575"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM01340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC93581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="619" mass="67328" checksum="7A015D5A9A070404" modified="2018-07-18" version="1">MTQSHSQIRPIQALPDNLISQIAAGEVVERPSAVVKELLENALDAGATQITVRLDQGGVKRIAITDNGRGIAPEQLPLAVARHATSKIASLTDLENVATLGFRGEALASIASVSQFMMSSRTADAEHAFQIENGVVSPTSGAPGTTVDVQELYYNTPARRKFLKTDQTEFGHCADVVRRLALARPDVTFTLTHNGKTVDHWNIASMDKRSAHIMGAEFAEARLAIDHSAGPLRLHGFAGLPTASKARADAQFFYVNGRFVRDKLLTHAVRAAYQDVLHGDRYPSYVLALQLDPSLVDVNVHPSKIEVRFRDGRAVHQFVFHAVQAALSHTSATAFGTAPAPLPAAVLYDANQPIPTTSANAWRPDGQSQQALFQRSNGYGVAQSTATYGALFTAPDTTPTPYQNTNVGLTNLSQFTTIKPETDTDEFPLGFALAQLHGIFVLAQNSRGMVLVDMHAAHERILYEQLKNALDEGAMTVQNLLIPVTFYADPQAVSVVEEQQDVLRSLGFEMAVLSPTTLAVRAIPSLLKNADAESLARDVLRDVGEFGASRVLLERRNEMLGTLACHSAVRANRSLTTVEMNALLRQMEHTERADQCNHGRPTWVQLALGDLDKLFLRGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0V5</accession>
    <name>A0A2S9H0V5_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">tRNA dimethylallyltransferase</fullName>
            <ecNumber evidence="5">2.5.1.75</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Dimethylallyl diphosphate:tRNA dimethylallyltransferase</fullName>
            <shortName evidence="5">DMAPP:tRNA dimethylallyltransferase</shortName>
            <shortName evidence="5">DMATase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Isopentenyl-diphosphate:tRNA isopentenyltransferase</fullName>
            <shortName evidence="5">IPP transferase</shortName>
            <shortName evidence="5">IPPT</shortName>
            <shortName evidence="5">IPTase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">miaA</name>
        <name evidence="9" type="ORF">S2091_1581</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 5 7">Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 5 6">
            <text>adenosine(37) in tRNA + dimethylallyl diphosphate = diphosphate + N(6)-dimethylallyladenosine(37) in tRNA</text>
            <dbReference type="Rhea" id="RHEA:26482"/>
            <dbReference type="Rhea" id="RHEA-COMP:10162"/>
            <dbReference type="Rhea" id="RHEA-COMP:10375"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57623"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74415"/>
            <dbReference type="EC" id="2.5.1.75"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="5">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 5 8">Belongs to the IPP transferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.75" evidence="5"/>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93580">
        <property type="protein sequence ID" value="PRC93580"/>
        <property type="gene ID" value="S2091_1581"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052381">
        <property type="term" value="F:tRNA dimethylallyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00185">
        <property type="entry name" value="IPP_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039657">
        <property type="entry name" value="Dimethylallyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018022">
        <property type="entry name" value="IPT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11088">
        <property type="entry name" value="PTHR11088"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00174">
        <property type="entry name" value="miaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 8" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 6" id="KW-0819">tRNA processing</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="13"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="region of interest" description="Interaction with substrate tRNA" evidence="5">
        <location>
            <begin position="36"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Interaction with substrate tRNA" evidence="5">
        <location>
            <begin position="160"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Interaction with substrate tRNA" evidence="5">
        <location>
            <begin position="242"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="11"/>
            <end position="18"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="site" description="Interaction with substrate tRNA" evidence="5">
        <location>
            <position position="102"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with substrate tRNA" evidence="5">
        <location>
            <position position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC93580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="313" mass="34768" checksum="38B07354E7C03E91" modified="2018-07-18" version="1">MMTPNVIAIMGPTASGKTAAALALAQHLPCEIISVDSALIYRQMDIGSAKPSAAELAAVPHHLIDIIDPAEAYSVAQFQTDVMELVQQISARGNVPLLVGGTMMYFKVLMNGLGDLPPANLEIRARLDAEIAANGVQSLHARLALLDPITATRLPPGDTQRIQRALEVIELTGQPLSTLFAQQTTIEPPLNIHAFSLEPSERSVLHQRIAQRFDVMLQQGFLDEVCALRARGDLNLNMPSMRCVGYRQAWEYLDGVYDLAELRERGIIATRQLAKRQLTWLRSMPERIVLDCLQPDVIQTMLQQLERWNYRSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H195</accession>
    <name>A0A2S9H195_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Gram-negative porin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_1721</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93720">
        <property type="protein sequence ID" value="PRC93720"/>
        <property type="gene ID" value="S2091_1721"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046930">
        <property type="term" value="C:pore complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015288">
        <property type="term" value="F:porin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006811">
        <property type="term" value="P:ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00342">
        <property type="entry name" value="gram_neg_porins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033900">
        <property type="entry name" value="Gram_neg_porin_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023614">
        <property type="entry name" value="Porin_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13609">
        <property type="entry name" value="Porin_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0406">Ion transport</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0626">Porin</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1134">Transmembrane beta strand</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Porin_4" evidence="4">
        <location>
            <begin position="24"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC93720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="338" mass="36171" checksum="FD1929AC4FB55057" modified="2018-07-18" version="1">MNSFTKNIFAIAVIGPVFFITTLHAQEVPIKFYGVLDAYVGSHKINGANTSAATALNSGGMTTSFWGLSGFEKINATLKVNFALEGFLLLDSGQGGRYTGDGMFSRSAYIGLSDQWGEVSVGRLTNPMYIMAAKSNPFGGSTRLSPLVNQNWIGAYGRNVVGDTAWSNSISYSSPSFNGVKLASQYGRSETGQQNMFAGLSYEQSPVSVQVGLQSVEYGPGVKAEGKKQSSYFIGAASQISTIKIFATYLHASTPDTVKSNNLQLGLAVPVAKGTVMLSSARTALNHHKTTNTHRLSSALGYRHPLSKRTDVYAIYLHDKLSIADAGHNIALGLRHAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1G4</accession>
    <name>A0A2S9H1G4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1707</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93706">
        <property type="protein sequence ID" value="PRC93706"/>
        <property type="gene ID" value="S2091_1707"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1890">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007410">
        <property type="entry name" value="PCuAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036182">
        <property type="entry name" value="PCuAC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36302">
        <property type="entry name" value="PTHR36302"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04314">
        <property type="entry name" value="PCuAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110087">
        <property type="entry name" value="SSF110087"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015634383" evidence="1">
        <location>
            <begin position="22"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="161" mass="17527" checksum="4B61EC4C6C3079D6" modified="2018-07-18" version="1">MLKRNLLILLSALALTSAVQAHEFKLGDIQIGHPYARATVPQQTSGGAFLALENTGKTDDKLIKVESSMANSVEIHNMEMVGDVMKMREVDLIDLKAGSKISMKPGGGYHIMLIGLKKQLNAGDKFPLTLQFEKAGKIEVMVFVEANTNTTPAASDMHDHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H254</accession>
    <name>A0A2S9H254_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HTH cro/C1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1237</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94064">
        <property type="protein sequence ID" value="PRC94064"/>
        <property type="gene ID" value="S2091_1237"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="11"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="243" mass="28344" checksum="991901D36E8FE428" modified="2018-07-18" version="1">MTEITQIVNALKRQLKAQGMTYRDLAKELDMSEAGVKRLFASERFTLERLAQISQLLGFTMAEIMQEASASIMKINMLTHDQEAQLVKDPKLLLITVCILNHWSIQEIESTYDLSQKEIFKRLMVLDRIGMIELLPANRIRLRVKRDFDWLQKGPIRQFFFKQGINDFLSGNYDQHNETLEFAHAMLTEPAINQFQIELRRLKNKLASLHEECIDAPLSKKRGTGLLVAMKEWEFDAFKQLRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2E8</accession>
    <name>A0A2S9H2E8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC-type nitrate/sulfonate/bicarbonate transport system permease component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_1327</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94154">
        <property type="protein sequence ID" value="PRC94154"/>
        <property type="gene ID" value="S2091_1327"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="33"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="97"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="127"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="156"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="196"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="246"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="90"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC94154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="290" mass="31680" checksum="7BF8A12ADA3166ED" modified="2018-07-18" version="1">MTTPFTPTPPLPSSTTGKEELQAIAKANKHHRLVIFLRFAVAIVTLATWEFAVHVEWLDGFFFSRPSSIIEQLFIWITEGTEQGPLWKELMVTLEETILGFLIGSFLGIFFGIALGRNKLMSDVFSIYIKIANAIPRIVLGSIFIIMFGLGLGSKIALAVVMVFFVVFGNAFQGVREADKNLIANAYILGANKRQVTFSVIFPSALTWILASLHVSFGFALVGAVVGEFLGARHGIGLLIATAQGTFNAAGVFAAMIILAVVALVAEYLLTALENKLLKWRPTQFVEHGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2I1</accession>
    <name>A0A2S9H2I1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ABC-type nitrate/sulfonate/bicarbonate transport system ATPase component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_1326</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94153">
        <property type="protein sequence ID" value="PRC94153"/>
        <property type="gene ID" value="S2091_1326"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-1278">Translocase</keyword>
    <feature type="domain" description="ABC transporter" evidence="7">
        <location>
            <begin position="6"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="43"/>
            <end position="50"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC94153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="258" mass="28588" checksum="65319319A66E133B" modified="2018-07-18" version="1">MKKIAIELTNVSRKFISPTGVSTLALHDFSMTLHEGDFCAIVGPTGCGKSTALGMITGLSPPSSGTVRVFNQPVTKIDPNIGFVFQADAVFPWKNVIDNISIGPIYRGTNKREAKDKAAEWVRRVGLSGFEYHYPHQLSGGMRKRVALAQTFINEPKILLMDEPFSALDVQTRALMQDELLGLWSENKASVVFVTHDIEEAIALADRVIVLTKGPGKIKSSYEINLPRPRDVSTARYSTEFINLSKQIWSDLKDEVHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2K2</accession>
    <name>A0A2S9H2K2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="10">TonB dependent receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">S2091_1360</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94187">
        <property type="protein sequence ID" value="PRC94187"/>
        <property type="gene ID" value="S2091_1360"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="3 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 10" id="KW-0675">Receptor</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="2 6" id="KW-0798">TonB box</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015534974" evidence="7">
        <location>
            <begin position="33"/>
            <end position="983"/>
        </location>
    </feature>
    <feature type="domain" description="Plug" evidence="9">
        <location>
            <begin position="64"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="8">
        <location>
            <begin position="382"/>
            <end position="979"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC94187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="983" mass="102945" checksum="8D3C703A16AA72BC" modified="2018-07-18" version="1">MMMETILSRSLRLMFSGGVALSIGLLAQPAFAQQVTDTPTDTTAAQPIQRVEITGSSIKRIQKEGALPVQVLTAADIKKTGATSVTDLIQNLPAMQGFATASTSVNGGGGGVTTAALHSLASQYTLVLLDGVRVATQGGAVNLESIPLDAIERVEILTDGASALYGSDAIAGVVNFILKKNKTDGDAYLTGQDPQHSGGRSWSAGVSKGFGDLDKDNFNVLLSYSHDTQKALEATQRSFSAQGGLIPFTANGKNYLFNQSSINSPIANLDIISAAPNDPTGANASEAIINPYALANAGSCGSNPNSYAHSTQCRFNYAATVQDIPSSTRDSGLAKATFKIDENTTAWATMMVSRYAMTAQYAASAQPFAINSTNLAGVNSTAYPNLFATYVQPYLNATGTVITGQNGGGVTAYYRTVAMGGRTDDYQTDAHHFSAGITSTAIPGWDLNAVVTLSNSVLKDTAAGGYGNFNEFNALVLSGAYDPVMNTGGASLQAAEITGQLLNKTTSNDNSIKVGAQHNLFEMPGGTSIISLGADFNHVSLQESYDPLQLASSGYASAPSGTNAVLGGTTAQVPFDASRNNVGLFGEWLLPLAKTLEGNIAGRYDSYSKVYSGYVFQTPALGGAQLSNADLGDTFSKATYKLSLRFTPTDTLLLRASYGTGFKAPSLGDIAATPTYAGSTAGSYSCPFPATPASCAGGLANPVQYDLLAGGNSASGSGGLKAENSKQWTLGFRVEPGFGLTAGADLWNVQIKDQVLGAGIPEATGFASPQTYSYLFTNPYTDPVGHYTTIGYSLVPLNGGVANYQGIDWDFAEKLKTPVGPLSLAWNGTYMMKQNYTFQQNGPVLTDLGAFGPDNSVVFRVQMHAIASLTTGNFTNSLTANYKSGYHDESYLAGTGAVKVVNADGSTTAVDYTGQVGSYTTFDWQGRYDYSKVLNFTAGIKNLFDKNPPLSLVNAGGGNQVGYDGRYADPLGRAFYLTGHYHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2L5</accession>
    <name>A0A2S9H2L5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_0821</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94200">
        <property type="protein sequence ID" value="PRC94200"/>
        <property type="gene ID" value="S2091_0821"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000485">
        <property type="entry name" value="AsnC-type_HTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019888">
        <property type="entry name" value="Tscrpt_reg_AsnC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019887">
        <property type="entry name" value="Tscrpt_reg_AsnC/Lrp_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019885">
        <property type="entry name" value="Tscrpt_reg_HTH_AsnC-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01037">
        <property type="entry name" value="AsnC_trans_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00033">
        <property type="entry name" value="HTHASNC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00344">
        <property type="entry name" value="HTH_ASNC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00519">
        <property type="entry name" value="HTH_ASNC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50956">
        <property type="entry name" value="HTH_ASNC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH asnC-type" evidence="4">
        <location>
            <begin position="3"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC94200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="170" mass="18897" checksum="9EB45AEB7802974C" modified="2018-07-18" version="1">MILDKIDRKILAILQADGRLSNQEVAERVNLSSSPCLRRIKRLEELGVIRQYVALLDPSKIGLGLLAYVNVRLEKHSDAPASTLGRATSASSPRSDFAASVAQWPEIVACYAMTGEMDYLLRVHVENMDHFSRFMMETLLRHPAVLDVKSSFALSQIKETTALPLTQISS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2L6</accession>
    <name>A0A2S9H2L6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="13">tRNA nucleotidyltransferase/poly(A) polymerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">S2091_0818</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="10">Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94197">
        <property type="protein sequence ID" value="PRC94197"/>
        <property type="gene ID" value="S2091_0818"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004810">
        <property type="term" value="F:tRNA adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042245">
        <property type="term" value="P:RNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001680">
        <property type="term" value="P:tRNA 3'-terminal CCA addition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05398">
        <property type="entry name" value="NT_ClassII-CCAase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012006">
        <property type="entry name" value="CCA_bact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002646">
        <property type="entry name" value="PolA_pol_head_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032828">
        <property type="entry name" value="PolyA_RNA-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01743">
        <property type="entry name" value="PolyA_pol"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12627">
        <property type="entry name" value="PolyA_pol_RNAbd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000813">
        <property type="entry name" value="CCA_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0692">RNA repair</keyword>
    <keyword evidence="9 10" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="1 10 13" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="PolyA_pol" evidence="11">
        <location>
            <begin position="4"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="domain" description="PolyA_pol_RNAbd" evidence="12">
        <location>
            <begin position="156"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF12627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PRC94197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="386" mass="42480" checksum="B175E3CCD12B1D7A" modified="2018-07-18" version="1">MKIYRVGGAVRDALLGLPVKDIDYLVLGSTPEQMVAAGFTPVGKDFPVFLHPKTQAEYALARTERKSAPGYHGFVFHCAPDVTIEQDLQRRDLTINAMAIAEDTGESDALNSVIIDPFGGQKDLAEKIFRHVSAAFSEDPVRILRVARFAARFNEFTVAPETIHLMRAMVTAGEVDALVPERVWQEIARGLMEAQPSRMMLVLRESGTLARIMPELDAIWDDSGSESELGMLQIVDNTAQRGLSLAVRWAALLSDLAGTANLAQQLCARLKVPTEVRDITLMALREQTQIELAITLTAEAIVQLFERCDAFRRPARFIEMLQAALCRQVTWPAPQLAYLEHALATAQAVPSGQIAQATAQLFPKQPQQIASAIAAARVDAIRYFTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2N0</accession>
    <name>A0A2S9H2N0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative enzyme related to lactoylglutathione lyase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0841</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94220">
        <property type="protein sequence ID" value="PRC94220"/>
        <property type="gene ID" value="S2091_0841"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004360">
        <property type="entry name" value="Glyas_Fos-R_dOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00903">
        <property type="entry name" value="Glyoxalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="4"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="123" mass="12962" checksum="3F662EE87CEBC787" modified="2018-07-18" version="1">MSNQLVWVDIPVTDLDRAIKFYSAVLGSPVSKEGGPGFIFGLFPHSDNDVGGCLYVPDADNAPSKVGPLIYLNAEGRLIDAVKAVAATGGKIIQDTHQIGPYGFRAVVLDTEGNRIALHAPTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H301</accession>
    <name>A0A2S9H301_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PilZ domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0934</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94313">
        <property type="protein sequence ID" value="PRC94313"/>
        <property type="gene ID" value="S2091_0934"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035438">
        <property type="term" value="F:cyclic-di-GMP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009875">
        <property type="entry name" value="PilZ_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07238">
        <property type="entry name" value="PilZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PilZ" evidence="1">
        <location>
            <begin position="11"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="117" mass="12881" checksum="93C8F8044B133401" modified="2018-07-18" version="1">MTTMTITKEGRSHLRRILHCKVKVISKNGSVLVGRSIDISLTGISVMLDEPFDHAPQCIIMFEALSANQLTSSKLINVTVNAEAVYSICVGTTGFRVGFKFDRINEEALKSLRLLLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H332</accession>
    <name>A0A2S9H332_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Dehydrogenases with different specificities (Related to short-chain alcohol dehydrogenases)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1013</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94392">
        <property type="protein sequence ID" value="PRC94392"/>
        <property type="gene ID" value="S2091_1013"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="239" mass="25186" checksum="2788F5066A66F4C9" modified="2018-07-18" version="1">MPKAIVIGGTAGIGQAIIKGLIEAGYSVHFTYNSNADSAEAIRLQYGDSCTCTQLNLSSLDAVSAFLATVDSANAPDVLVNSAGMAADSLSLGDVRARLEQATTINYLAPVTIACHIGKLMTERRTGSIVNITSIASKRPKAGNAIYGSAKAALERFTATLALEMARFKVRTLCVSPGFVDTPMFQKFSGGNARDIIREIPTREILTADQVAETVLLFVKGHIKSTGTTLVLGNGELVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H363</accession>
    <name>A0A2S9H363_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Twitching motility protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1046</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GSP E family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94425">
        <property type="protein sequence ID" value="PRC94425"/>
        <property type="gene ID" value="S2091_1046"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006321">
        <property type="entry name" value="PilT/PilU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001482">
        <property type="entry name" value="T2SS/T4SS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00437">
        <property type="entry name" value="T2SSE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01420">
        <property type="entry name" value="pilT_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="T2SP_E" evidence="2">
        <location>
            <begin position="122"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="378" mass="42037" checksum="6F3605931FB1A8F2" modified="2018-07-18" version="1">MERDQATKFMNDLLRLMLTKNGSDLFITADFPPAFKIDGKVTPVSNQPLTAAHTIELARSIMNDKQAAMFEQTKECNFAINPAGLGRFRVSAFVQQSRVGMVLRTITTTIPKFEDLGLPAILNDIAMTKRGLVIMVGATGSGKSTSLAAMVGYRNANSYGHIITVEDPIEYVHPHNNCIVTQREVGIDTEDWGAALKNSLRQAPDVIQIGEIRDRETMDHAIAFAETGHLCLATLHANSTNQALDRIINFFPEERRQQLLMDLSLNLKAVVSQRLIPLRGTKGRCAALEILINSPLIGDLIFKGQVHEIKEVMKKSREHGMQTFDQSLFELYEAQKISYEDALRNADSVNELRLAIMLHGKEAKERDLNSGTQHLGIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H368</accession>
    <name>A0A2S9H368_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Ogt: methylated-DNA-[protein]-cysteine S-methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">S2091_1031</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 4-O-methyl-thymidine in DNA + L-cysteinyl-[protein] = a thymidine in DNA + S-methyl-L-cysteinyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:53428"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:10132"/>
            <dbReference type="Rhea" id="RHEA-COMP:13555"/>
            <dbReference type="Rhea" id="RHEA-COMP:13556"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:82612"/>
            <dbReference type="ChEBI" id="CHEBI:137386"/>
            <dbReference type="ChEBI" id="CHEBI:137387"/>
            <dbReference type="EC" id="2.1.1.63"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>a 6-O-methyl-2'-deoxyguanosine in DNA + L-cysteinyl-[protein] = a 2'-deoxyguanosine in DNA + S-methyl-L-cysteinyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:24000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:10132"/>
            <dbReference type="Rhea" id="RHEA-COMP:11367"/>
            <dbReference type="Rhea" id="RHEA-COMP:11368"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:82612"/>
            <dbReference type="ChEBI" id="CHEBI:85445"/>
            <dbReference type="ChEBI" id="CHEBI:85448"/>
            <dbReference type="EC" id="2.1.1.63"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="11">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94410">
        <property type="protein sequence ID" value="PRC94410"/>
        <property type="gene ID" value="S2091_1031"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003908">
        <property type="term" value="F:methylated-DNA-[protein]-cysteine S-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06445">
        <property type="entry name" value="ATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035451">
        <property type="entry name" value="Ada-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004026">
        <property type="entry name" value="Ada_DNA_repair_Zn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016221">
        <property type="entry name" value="Bifunct_regulatory_prot_Ada"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018062">
        <property type="entry name" value="HTH_AraC-typ_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001497">
        <property type="entry name" value="MethylDNA_cys_MeTrfase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014048">
        <property type="entry name" value="MethylDNA_cys_MeTrfase_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036217">
        <property type="entry name" value="MethylDNA_cys_MeTrfase_DNAb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036631">
        <property type="entry name" value="MGMT_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02805">
        <property type="entry name" value="Ada_Zn_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01035">
        <property type="entry name" value="DNA_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000409">
        <property type="entry name" value="Ada"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46767">
        <property type="entry name" value="SSF46767"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53155">
        <property type="entry name" value="SSF53155"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57884">
        <property type="entry name" value="SSF57884"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00589">
        <property type="entry name" value="ogt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00041">
        <property type="entry name" value="HTH_ARAC_FAMILY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00374">
        <property type="entry name" value="MGMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0227">DNA damage</keyword>
    <keyword evidence="9" id="KW-0234">DNA repair</keyword>
    <keyword evidence="8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 13" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 13" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 11" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="12">
        <location>
            <begin position="97"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile; methyl group acceptor from methylphosphotriester" evidence="10">
        <location>
            <position position="47"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile; methyl group acceptor from either O6-methylguanine or O4-methylthymine" evidence="10">
        <location>
            <position position="331"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="47"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000409-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000409-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PRC94410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="359" mass="38985" checksum="C73D0852FED8C58F" modified="2018-07-18" version="1">MKPRLTLPSVLPPKSSADDIRWAAVQGRDAATDGDFVYGVKTTGIYCRPSSSARLPKRENVEFFDNAQAAEAAGYRPSRRASADRTAAATQRTALVAKACRLIENAEVQPNLDALAEQAGMSTFHFHRIFKAETGLTPKAYSSASRARRMRGELGGSGTITDAIYGSGFNSNSRFYEASVGMLGMRPRDYKDGGYNAEIRFAVGQCSLGAILVAQSQRGICAILLGDDPDLLVRDLQDQFRKAHLIGGDADFEQLIAQVVGFIEAPALGLKLPLDVQGTAFQERVWQALREIPPGMTASYSDIAERIGSPKAVRAVAQACAANHIAVAIPCHRVVRRNGDISGYRWGVERKRELLQREA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3C1</accession>
    <name>A0A2S9H3C1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0487</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94484">
        <property type="protein sequence ID" value="PRC94484"/>
        <property type="gene ID" value="S2091_0487"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="70" mass="7690" checksum="D404BFE578EE34A5" modified="2018-07-18" version="1">MESFGHVVSESGGKNAMPFCETKSGSFRSPDEIVAELIMFNVLKEYALDFVLQGPPAKLIKLRNRNAVSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3H2</accession>
    <name>A0A2S9H3H2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Adenosylmethionine-8-amino-7-oxononanoate aminotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0537</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94534">
        <property type="protein sequence ID" value="PRC94534"/>
        <property type="gene ID" value="S2091_0537"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00610">
        <property type="entry name" value="OAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000521">
        <property type="entry name" value="Transaminase_4ab_Lys_Orn"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00600">
        <property type="entry name" value="AA_TRANSFER_CLASS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="1 2" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="449" mass="48735" checksum="056005EB7894751A" modified="2018-07-18" version="1">MTQTDQQHLMSTRQDAAWLDAHWMPYTGNRNFKANPRMIVGAKGNYYFDAQGNKILDGLSGLWCSGLGHGRTEITEAVSRQMATLDYAPAFQFGHPLSFELANRIKEITPAGLDYVFFTGSGSEAADTSLKMARAYWRAKGQASKTLLIGREKGYHGVNFGGISVGGIAANRKVFGQAVGADHLPHTLLAQNAFTRGLPENGVELADELLNIIALHDASNIAAVIVEPFSGSAGVIVPPVGYLKRLREICTQHNILLIFDEVITAFGRVGAYTAAEKFDVTPDILNFAKQITNGAQPLGGVVVKKEIYDIFMEQGGQDYMLEFPHGYTYSAHPVACAAGIATLKLLEQENMLERVNSLTPYFENAVHSLMGSNHVTDIRNCGLAAGFTFAAFPGEPAKRPYEIAMKCLKKGFYVRYGGDTIQLAPPFTIEKSEIDSLVNALGEAISATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3Q5</accession>
    <name>A0A2S9H3Q5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ergothioneine biosynthesis protein EgtB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0594</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94591">
        <property type="protein sequence ID" value="PRC94591"/>
        <property type="gene ID" value="S2091_0594"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052699">
        <property type="term" value="P:ergothioneine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1580.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024775">
        <property type="entry name" value="DinB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017806">
        <property type="entry name" value="EgtB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005532">
        <property type="entry name" value="SUMF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042095">
        <property type="entry name" value="SUMF_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12867">
        <property type="entry name" value="DinB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03781">
        <property type="entry name" value="FGE-sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="SSF56436"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03440">
        <property type="entry name" value="egtB_TIGR03440"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DinB_2" evidence="2">
        <location>
            <begin position="19"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="domain" description="FGE-sulfatase" evidence="1">
        <location>
            <begin position="195"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="417" mass="47938" checksum="A7DA6D04DE1DA1CC" modified="2018-07-18" version="1">MQVQTETDPKISAHLLQRFNEVRKFSVSLAKPLSEEDCCIQSMPDASPMKWHLAHTTWFFETFILERFEINFRPYHQAYRVLFNSYYNGVGQKHPRAQRGLLSRPSTNEVIAYRHNVDMRMGALLERAISNDSVSESILDLISLTELGIQHEQQHQELMLTDIKHMLSMNPLFPAYENSLPVRHRSSLENADKVTWISLDAGVVMIGYDAISFCFDNEIPRHRQFVEAFSMASRLVTNAEYAVFIDAGGYRNPVHWLAEGWDWVRNQGLTQPLYWYRPDDKLWHEFTLHGLQRLDPQAPAIHLSYFEADAYAHWAGARLPTEFEWEMAATTSSSSAQLLQLFGTAWQWTSSSYAPYPGFVAAEGVVGEYNGKFMVNQYVLRGSSCVTPVGHTRTTYRNFFSVGARWQFTGIRLAKSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H427</accession>
    <name>A0A2S9H427_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative heavy-metal-binding</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0731</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0145 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94728">
        <property type="protein sequence ID" value="PRC94728"/>
        <property type="gene ID" value="S2091_0731"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002765">
        <property type="entry name" value="UPF0145"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035439">
        <property type="entry name" value="UPF0145_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34068">
        <property type="entry name" value="PTHR34068"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01906">
        <property type="entry name" value="YbjQ_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117782">
        <property type="entry name" value="SSF117782"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="360" mass="38183" checksum="A744590056368602" modified="2018-07-18" version="1">MNLKGYRAAGILIGNSVQSMGFFGGLTSGFRGVMGGEIKEVTDMIHAGRQAAFIHMVNEAKHESVHGIVGVSSELRGLAGNSEFLFVGSGVLGNNPGKLFTSAGDAQELYCHMDAGYDPIHFVFGNIAYSVGLVGGIFGSLKTLMRGEIREFSDIFNETRHHALSRLVSGAVRAGANAVVGIRTNVMRFNGFHEMVMSGTAARHPHLPVECDQLPVTSDLTGEELWALSSMGYAPIKLLISTSVYSLGAIGGVKAIFRGLAQGEIGELTTLVYDARENVFDRLKSEANAIGAEEVVGTKTYIVELGSGLIEIVAIGTAVRKLPGFSVQTATLPCQAIIRDKDTWLNGDGGFELQSIRAGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H430</accession>
    <name>A0A2S9H430_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0747</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94744">
        <property type="protein sequence ID" value="PRC94744"/>
        <property type="gene ID" value="S2091_0747"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="39" mass="4280" checksum="C31CD7C77367AF76" modified="2018-07-18" version="1">MAPEFIAQTLVPQYHGAGNMNERSEMVVMVIPTRLSSCA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H434</accession>
    <name>A0A2S9H434_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Calcineurin-like phosphoesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0748</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94745">
        <property type="protein sequence ID" value="PRC94745"/>
        <property type="gene ID" value="S2091_0748"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP_ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallophos" evidence="1">
        <location>
            <begin position="2"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="305" mass="34761" checksum="E846D319B49C4B8C" modified="2018-07-18" version="1">MNYDIIGDIHGHSDKLTTLLAKLGYREQAGAWRHSEKTAIFVGDFVDRGPGQLATIDIVRRMVDCGSAQAVLGNHEFNAIAWHTPDPAHDGEYLRVHRPKNRHQHAAFLAEVEHDKARHKEVIDWFMTLPLWLELDELRVIHACWHPAYMNELEPYLDKENRLTQVVVEAANNPESVLFQSVEALIKGLQIKLPDGVFYFDEDGHKRNKVRTCWWDADATTYRRAALLARAERERLPTDQIPASARILYANDKPLFIGHYWNRGALAPLTPHIACVDYSVGKGGALVAYRWEGESELKARQFVAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4C4</accession>
    <name>A0A2S9H4C4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Alpha/beta hydrolase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_0012</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AB hydrolase superfamily. Lipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94817">
        <property type="protein sequence ID" value="PRC94817"/>
        <property type="gene ID" value="S2091_0012"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004806">
        <property type="term" value="F:triglyceride lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005152">
        <property type="entry name" value="Lipase_secreted"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34853">
        <property type="entry name" value="PTHR34853"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015448119" evidence="3">
        <location>
            <begin position="20"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S9" evidence="4">
        <location>
            <begin position="152"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="21"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC94817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="534" mass="54968" checksum="A3A84B2B970CDC53" modified="2018-07-18" version="1">MQKLTGLVLVSTFILTACGGSDSNSSSTAGGVGISDARGTLQQNPPPLTVSMSTSAITANPSWQQNVTIFGSAPICGVDIHYLKFGTVGGAGEATNATGALMLPTGSNPACSGPRPIVVYAHGTAFTKAYNLASSDPNNEANGETLMIAVDFAAQGFIVVATNYAGYDTSQLPYHPYLNADQQSKDVIDSLTAARAALPSLGGATDSGKLFITGYSQGGFVAMATHKAMQAAGQTVTAAAPSSGPYAMGAFGDTVFLGRPSLLINVLATMIVTSYQHAYGNIYANLTDIYNPTYAANLANILPSSEGLNVLSTGLIAPSIFSNIAPTAPVGASASLQAVLNADTIPPTSPALLASTYAAGFGPNFLVTNNYRINYIMDALANPDGSVPTLTTGLPAVSPANTIRQGFKINDFRNWTANRPVLLCGGNADPMVYFNANTQNMQQYWTAPSPAAMASGLFTVLDVDSAITGANDPYASAKTVFTDLRAYFVEQAIASGATDGGASAVLQNYHPVLVSSACMLAASNFFQQVLASGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4I1</accession>
    <name>A0A2S9H4I1_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Isocitrate dehydrogenase [NADP]</fullName>
            <ecNumber evidence="3">1.1.1.42</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_0084</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>D-threo-isocitrate + NADP(+) = 2-oxoglutarate + CO2 + NADPH</text>
            <dbReference type="Rhea" id="RHEA:19629"/>
            <dbReference type="ChEBI" id="CHEBI:15562"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.42"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="3">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.42" evidence="3"/>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94889">
        <property type="protein sequence ID" value="PRC94889"/>
        <property type="gene ID" value="S2091_0084"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004450">
        <property type="term" value="F:isocitrate dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006097">
        <property type="term" value="P:glyoxylate cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019818">
        <property type="entry name" value="IsoCit/isopropylmalate_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004439">
        <property type="entry name" value="Isocitrate_DH_NADP_dimer_prok"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024084">
        <property type="entry name" value="IsoPropMal-DH-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43504">
        <property type="entry name" value="PTHR43504"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00180">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01329">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00183">
        <property type="entry name" value="prok_nadp_idh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00470">
        <property type="entry name" value="IDH_IMDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0329">Glyoxylate bypass</keyword>
    <keyword evidence="3" id="KW-0464">Manganese</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0521">NADP</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="Iso_dh" evidence="4">
        <location>
            <begin position="29"/>
            <end position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM01329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC94889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="417" mass="45797" checksum="28F783837222C359" modified="2018-07-18" version="1">MYQHIKVPTDGQKITVNADYSINVPHNPIIPYIEGDGTGVDISPVMIKVIDAAVAKAYGGQRKISWMEIYAGEKSTQVYGPDVWLPEETLRVLKDYVVSIKGPLTTPVGGGIRSLNVALRQELDLYVCLRPVRYFKGVPSPVREPEKTDMVIFRENSEDIYAGVEFQEGSDQVKKLIAFLVNEMGVKKIRFPETSGIGIKPVSREGTERLVRKAIQYAIDNDKPSVTIVHKGNIMKYTEGGFRDWAYALAQKEFGAELIDGGPWCKFKNPKTGKEIIVKDSIADAFLQQILLRPAEYSVIATLNLNGDYISDALAAQVGGIGIAPGANLSDSIAMFEATHGTAPKYAGKDYVNPGSLILSAEMMLRHMGWLEAADLLISSMSKSIAQKRVTYDFARLMEGATQLSCSGFGDAMIENM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4M4</accession>
    <name>A0A2S9H4M4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0112</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94917">
        <property type="protein sequence ID" value="PRC94917"/>
        <property type="gene ID" value="S2091_0112"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="2"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="295" mass="32099" checksum="89B103261DB27C8E" modified="2018-07-18" version="1">MINPQHLAIFVSIVQAGSISGAATLLGCGKSVVSRQLAKLEDDLGARLIQRSTRRLALTEIGEMVLAEARKIEHSLNNIDLITDQFQQQVRGLLRVSCSMAGRRQVVPLIAEFTRLYPQVKVALQLEDHLVDLIKEQIDVAIRVSHLPDSTLVARKLAENPRMLVASPAYLAQSGTPQTPAQLTEHACLVYANEGRVYDEWTFSGQPEPFKVKVGGAIQINDGGALVTAACCGAGILLIPRKIVAEELANGELVEVLENWPLPAGAPIYAVYPARDWLALKTSAFVGFMQERMSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4V7</accession>
    <name>A0A2S9H4V7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glutathione S-transferase, N-terminal domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_0215</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GST superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95020">
        <property type="protein sequence ID" value="PRC95020"/>
        <property type="gene ID" value="S2091_0215"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00043">
        <property type="entry name" value="GST_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02798">
        <property type="entry name" value="GST_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="SSF47616"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GST N-terminal" evidence="2">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="3">
        <location>
            <begin position="97"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC95020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="232" mass="26308" checksum="CCCAA78BEFB233DA" modified="2018-07-18" version="1">MLTLHHLETSRSQRILWLLEELKVPYQIVRYQRDKKTRLAPPELKAIHPLGKSPVITDGDITVAESGAILEYLADKYGYLGKEDATGELTNIVPAPNTPEHLQCRFWMHYAEGSLMNWLVMKLVFMTIPTQPMPFFVRPIARQLCAKVLVKLVDPNVTTALTFIDNHLASHPWFAGDEITLADFQMSFAVEAGLARGNHARQFTHLSAYREKMVQRPAYQRAIKIGGPVIMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4W6</accession>
    <name>A0A2S9H4W6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0203</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95008">
        <property type="protein sequence ID" value="PRC95008"/>
        <property type="gene ID" value="S2091_0203"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC95008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="97" mass="11202" checksum="6E98850F4FE78F98" modified="2018-07-18" version="1">MNYAAELFHPHLNTPFFIQFQDKQQTELLLEEVKNQSSVNSSFHQFSLFFTGPHTDQLGQGTYTLTHASLPEHAIFLVPVAKTEHGYRYQACFNIKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4X9</accession>
    <name>A0A2S9H4X9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Outer membrane protein W</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0240</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95045">
        <property type="protein sequence ID" value="PRC95045"/>
        <property type="gene ID" value="S2091_0240"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011250">
        <property type="entry name" value="OMP/PagP_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005618">
        <property type="entry name" value="OMPW"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36920">
        <property type="entry name" value="PTHR36920"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03922">
        <property type="entry name" value="OmpW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56925">
        <property type="entry name" value="SSF56925"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015542181" evidence="2">
        <location>
            <begin position="23"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC95045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="222" mass="23486" checksum="606F01B21001DB5D" modified="2018-07-18" version="1">MKKIVKLMGCALLLSASAGAMAQEAGTIMVKAGYAYFDPVVSSGNLSAPSLPGTKMDVGTAGTLLLTGTYMFTDHISAEFYGGIPLKHDIYGAGSIQGVGVIGTVKQLPPTLFGQYRFFETSSNFRPYLGLGVTYVHFEDETGNAVLTAITNPGGSGTTFKVKDAWGVVPQAGITSWINKQWYIDISVNKSFVKTTTTLSTGQTIATALNPVVTQASIGYRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H535</accession>
    <name>A0A2S9H535_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Leucine--tRNA ligase</fullName>
            <ecNumber evidence="9">6.1.1.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Leucyl-tRNA synthetase</fullName>
            <shortName evidence="9">LeuRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">leuS</name>
        <name evidence="15" type="ORF">S2091_0297</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>ATP + L-leucine + tRNA(Leu) = AMP + diphosphate + L-leucyl-tRNA(Leu)</text>
            <dbReference type="Rhea" id="RHEA:11688"/>
            <dbReference type="Rhea" id="RHEA-COMP:9613"/>
            <dbReference type="Rhea" id="RHEA-COMP:9622"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57427"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78494"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.4"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9 10">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.4" evidence="9"/>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95102">
        <property type="protein sequence ID" value="PRC95102"/>
        <property type="gene ID" value="S2091_0297"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA editing activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004823">
        <property type="term" value="F:leucine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006429">
        <property type="term" value="P:leucyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00049_B">
        <property type="entry name" value="Leu_tRNA_synth_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002300">
        <property type="entry name" value="aa-tRNA-synth_Ia"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002302">
        <property type="entry name" value="Leu-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025709">
        <property type="entry name" value="Leu_tRNA-synth_edit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013155">
        <property type="entry name" value="M/V/L/I-tRNA-synth_anticd-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015413">
        <property type="entry name" value="Methionyl/Leucyl_tRNA_Synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009008">
        <property type="entry name" value="Val/Leu/Ile-tRNA-synth_edit"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43740">
        <property type="entry name" value="PTHR43740"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08264">
        <property type="entry name" value="Anticodon_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00133">
        <property type="entry name" value="tRNA-synt_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13603">
        <property type="entry name" value="tRNA-synt_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09334">
        <property type="entry name" value="tRNA-synt_1g"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00985">
        <property type="entry name" value="TRNASYNTHLEU"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="SSF47323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50677">
        <property type="entry name" value="SSF50677"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00396">
        <property type="entry name" value="leuS_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9 10" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="6 9 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 9 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 9 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 9 10" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="tRNA-synt_1g" evidence="13">
        <location>
            <begin position="41"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="domain" description="tRNA-synt_1_2" evidence="14">
        <location>
            <begin position="224"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="domain" description="tRNA-synt_1" evidence="11">
        <location>
            <begin position="431"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="domain" description="tRNA-synt_1" evidence="11">
        <location>
            <begin position="633"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="domain" description="Anticodon_1" evidence="12">
        <location>
            <begin position="718"/>
            <end position="839"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'HIGH' region" evidence="9">
        <location>
            <begin position="45"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'KMSKS' region" evidence="9">
        <location>
            <begin position="634"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="637"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF08264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF09334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF13603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="PRC95102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="876" mass="98077" checksum="83742B8EEBE47C76" modified="2018-07-18" version="1">MQEKYSPSDVEQQAQAHWQHIDAYRTQENDPRFPKGKYYACSMLPYPSGKLHMGHVRNYTINDMLSRQLRMKGFNVLMPMGWDAFGLPAENAAIAYNKSPAEWTYANIADMKSQMQPLGLAFDWTREVATCDPDYYRWNQWFFLKLLDKGVAYKKTQVVNWDPIDQTVLANEQVVDGRGWRSGALVEKREIPGYYFGITQYAEELLSSIDDLDGWPEQVRTMQRNWIGKSEGVRFAFPHQIKDEAGELIQDGKMYVFTTRADTIMGVTFCAVAAEHPLATLAAKNNPALAAFIEVCKTGGTTEAEMATKEKEGMPTGLFVTHPVTGKQVEVWVGNYVLMTYGDGAVMGVPAHDERDFAFAKKYSIAIEQVIAADGCSFSLDGWQEWYGDKQRAVTVNSGKYDGLNHAAAVQAVAADLVAQGLGEKKTTWRLRDWGISRQRYWGTPIPIIHCDACGAVPVPEKDLPVILPTDCIPDGSGNPLKHRADFLNVACPTCGAAAQRETDTMDTFVDSSWYYMRYTCPDATSMVDSRNDYWMAMDQYIGGVEHAVMHLLYARFWTKAMRDLGLVKFDEPFKNLFTQGMLLNESFYREDATGKKTWYYPNEIEVAYDEKGRPVSASLKSDGIAVQMGGIEKMSKSKNNVVEPKDIISRFGADTARLFTMFAGPPDQSAAWSDTGVEGAARYLRRLWANAHKHLDTVRGAGKIDPTADYAEPVKALRREVHLTLKQIDYDYDKLQYNTVVSGAMKLLNAIEAFKAEGNGHAAVLKEAFSILLRSLYPVCPHICHALWQNMGMDASIEIINAPWPQLDEAALIQNEIEYMVQVNGKLRGAIKVARDADKASIEATALSHEHVQKFLTGTPKKVIVVPGKLINIVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5B0</accession>
    <name>A0A2S9H5B0_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">S2091_0367</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95172">
        <property type="protein sequence ID" value="PRC95172"/>
        <property type="gene ID" value="S2091_0367"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036641">
        <property type="entry name" value="HPT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008207">
        <property type="entry name" value="Sig_transdc_His_kin_Hpt_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01627">
        <property type="entry name" value="Hpt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47226">
        <property type="entry name" value="SSF47226"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50894">
        <property type="entry name" value="HPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="10" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Response regulatory" evidence="8">
        <location>
            <begin position="4"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="8">
        <location>
            <begin position="137"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="8">
        <location>
            <begin position="273"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="7">
        <location>
            <begin position="473"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="8">
        <location>
            <begin position="709"/>
            <end position="831"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="8">
        <location>
            <begin position="853"/>
            <end position="971"/>
        </location>
    </feature>
    <feature type="domain" description="HPt" evidence="9">
        <location>
            <begin position="1008"/>
            <end position="1098"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="391"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="5">
        <location>
            <position position="53"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="5">
        <location>
            <position position="186"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="5">
        <location>
            <position position="322"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="5">
        <location>
            <position position="763"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="5">
        <location>
            <position position="904"/>
        </location>
    </feature>
    <feature type="modified residue" description="Phosphohistidine" evidence="4">
        <location>
            <position position="1047"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC95172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="1185" mass="129903" checksum="CC077A1CE1B99884" modified="2018-07-18" version="1">MSKVIMIVDDSLTVRADLEEAFTAEGLPTICCASAAQARATFGTQEIGLVVLDVLLPDGDGIDLLREFRATPAGADIPVLMLSSEAEVKDRIRGLLTGSSEYIGKPYDRDHVMARARELLGTKRPERKREQVGEKALVLVIDDSATFRERFGDLLREQGFDVLCAESGEEGLRSAAINRPAAIVIDGVLPGIDGPTVVRKLRLDAALRHTPCIMLTGSESFDAELRALDSGADAFVRKEEDLEMILARVTAVLRNVGKVEARHETVSLQGPKRILAVDDSLTYLHELNDTLNGEGYDVILAHSGEEALDMLAVQTVDCILLDRLMPGIDGTETCRRIKASATTRDIPLIMLTAMEDREAMIEGLSTGADDYVLKSSEMDVLKARVRAQLRRKQFEEESRRIRLELMSKELEATEARAARSLAESRAELLAVLERKNQDLETAVDLLRQGQQEIEERNQQLQEANRLKSEFVSNMSHEIRTPMNAILGFAYLLDQRQLDGDSADLVRKIRNAGRTLQSIINDILDFSKIEAGRLEIERAPLRINDIFDNLSDIMAANAGHKDLELVISPPPDIGGQLYGDALRIEQVLINLTGNAIKFSEHGAIRVGINLLEKTDKVATMRFSVTDSGIGIPVEQQSQIFAAFSQADASTTRRFGGTGLGLTICRHLVKNMGGEIGVVSEPGKGSEFWFTVPFEWSSMTEFAPPEMLTLDVLIVDDNEIALNNLRLIARSIGWNVTKAESGEIALQKIRAKHELNANYNVLLVDWKMPGMDGLTTALKMREEFSDEPTAIVLMVAAFSRDELLRQPDVDAVDGILCKPVTSSTLYNSVAEALRRIAGGLSKSEERNIKRIPGVRILIVDDSEINREVAMRIVTTDGAIVSLANNGKDALEWLCSSQNVVDIVLMDVQMPVMDGYEATRQLRSLPQFADLPIVALTAGAFKAQQDDALTAGMNAFVSKPFNVEELVTTIQRLTYCQPLLKGAAQRGSGTATDFGNLPGIEVEKGLSVWRDVAMYRKFLVKFCSDFADSSDLLDSYFASGNHETAQALLHKLKGAAGNMALFDVARLAAEVEAIELSTGLSDGLRQLRSALAIAFSSVAKFAAQAEEEATSDLVAANVKPLHQILPELLQALDSDAPDNANRLVASMKALLIPDFIAQLEARIDSFDFRGAEALVRRLIDNPQLGVRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5C0</accession>
    <name>A0A2S9H5C0_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Aamy domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_0379</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95184">
        <property type="protein sequence ID" value="PRC95184"/>
        <property type="gene ID" value="S2091_0379"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051060">
        <property type="term" value="F:pullulanase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="Glyco_hydro_13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004193">
        <property type="entry name" value="Glyco_hydro_13_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024561">
        <property type="entry name" value="Pullul_strch_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040671">
        <property type="entry name" value="Pullulanase_N2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045041">
        <property type="entry name" value="Pullulanase_PULA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43631">
        <property type="entry name" value="PTHR43631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02922">
        <property type="entry name" value="CBM_48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11852">
        <property type="entry name" value="DUF3372"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17967">
        <property type="entry name" value="Pullulanase_N2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00642">
        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="SSF81296"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015579398" description="Aamy domain-containing protein" evidence="2">
        <location>
            <begin position="32"/>
            <end position="919"/>
        </location>
    </feature>
    <feature type="domain" description="Aamy" evidence="3">
        <location>
            <begin position="400"/>
            <end position="752"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC95184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="919" mass="101430" checksum="CD579BF61EACB032" modified="2018-07-18" version="1">MVFEIVQSIYSKLSYFALMSGFFLCSTLAAASQPATIDDCNGDDFQTSLQAQHHAEPNTKDARAIWLNQRLIKWPGLNASANFRLYYSASSNLHVVEGTHMQGADGVLALEPTSSPLPTALATRFNFVADGIILKLHATDSKKVAQLLQQQLILVQENSLGEVIDSTRIQIAGALDDLYTSAQYIDDFGATVIDRGDSHATQFKLWAPTAQRVSLCLYENGQGGAEQIAAMQRVSATGHWQYTIPKNLTGHYYKYVVDVVVPGIGLVRNRVTDPYSISLTTDSKRSYITQVDAPQTVPNGWRQSRAPQSIRKQTDMTIYELHVRDFSINDQSVSAAHRGKYLAFTELGSNGMQHLATLVKASLTDVHLLPVFDFASVQETGCDHLAINSQDDVVDPVNKTVSTACFNWGYDPFHYNAPEGSYATDPADGATRMLEFRQMVMALHRIGLRVGMDVVYNHTYAAGQQPKSVLDRIVPGYYHRLNALGAIEQSTCCDNTATENRMMSKLMIDSVVSWARNYQIDSFRFDLMAHQPRSVMEALQKKLKSSINHPIQLIGEGWNFGEVADGARFVQASQLSLNGSGIATFNDRLRDAVRGGSASDSGADLVNRKGYINGLADQGNSSAGLLQVADLVRVGLAGSLRDYQLLTYDGQKKSLKEINYNGQPAGYVSQPTEVVNYVENHDNQTLFDINAYKLPTDTTRIDRVRVQMLGAAITAFSQGVAYFHAGIDVLRSKSMDSNSFNSGDWFNRLDWTYQDNYFATGLPPKPDNEKNYPLIKERLENPLIKPTGNEIGMARAMFSDLLKIRASSTLFRLGTAEDIEQRLRFENVGPLQNGSLIVAHLDGKNYPGANYQSILYFINVASTEQTIRLASEKGQAYVLHPVQSNVAAADKRVAKEAAYDALTGQFTIPARSSVVFVVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5N1</accession>
    <name>A0A2S9H5N1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_0381</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95186">
        <property type="protein sequence ID" value="PRC95186"/>
        <property type="gene ID" value="S2091_0381"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01392">
        <property type="entry name" value="HTH_LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000843">
        <property type="entry name" value="HTH_LacI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001761">
        <property type="entry name" value="Peripla_BP/Lac1_sug-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00356">
        <property type="entry name" value="LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00532">
        <property type="entry name" value="Peripla_BP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00354">
        <property type="entry name" value="HTH_LACI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50932">
        <property type="entry name" value="HTH_LACI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH lacI-type" evidence="4">
        <location>
            <begin position="3"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC95186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="337" mass="37201" checksum="E55299304B183054" modified="2018-07-18" version="1">MSINLKNLAKNLGISETTVSRALNGYPEVSERTRERVLAAAQLAGYRPNPVARSLASGRTNVIGIIHPLPNDLADPMFMQIVGGMTQALEERQMDLIIAPVSQMNELRAYQHMVQERRVDGLIVARTRLYDERVAYLANQGLPFVAHGRTRVNEPHAWFDYDNEAGMSMAVQHLLSYGHSRIGLISAPLEMNFARQRFDSFKFSLQTAGISADPSHLIDGANDRRSGYLAMQRLLQNPSVPTAVIVDNHMSGVGAIRAMLDANIDIGKNMSIIVWGRMEDSLAGYNVTTIEQPNPDKAGIKMVEMLLALQSGTPPSELQELWQPILIAGETVSQIKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5P8</accession>
    <name>A0A2S9H5P8_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Tol-Pal system protein TolQ</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">tolQ</name>
        <name evidence="10" type="ORF">S2091_0473</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell inner membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the ExbB/TolQ family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95278">
        <property type="protein sequence ID" value="PRC95278"/>
        <property type="gene ID" value="S2091_0473"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043213">
        <property type="term" value="P:bacteriocin transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02202">
        <property type="entry name" value="TolQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002898">
        <property type="entry name" value="MotA_ExbB_proton_chnl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014163">
        <property type="entry name" value="Tol-Pal_TolQ"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01618">
        <property type="entry name" value="MotA_ExbB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02796">
        <property type="entry name" value="tolQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="8" id="KW-0132">Cell division</keyword>
    <keyword evidence="4 8" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="3 8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="131"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="174"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="domain" description="MotA_ExbB" evidence="9">
        <location>
            <begin position="82"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC95278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="226" mass="25013" checksum="7DB058D467D90021" modified="2018-07-18" version="1">MMTVTQDLSFITLITNASIIVQIVMAMLLCVSLMSWNYIFRKRFAIKKARIQTEKFEREFWSGGSLNELYKSLDHRREQSGALERIFGAGMNEFHKNRATAGTDSAAMLDGARRAMRAAYQREMDALDSHLSFLASVGSVSPYVGLFGTVWGIMNAFRGLANVQQATLAAVAPGIAEALVATAIGLFAAIPALVAYNSCTHDIDRLAIRFESFVEEFSNILQRQGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GS52</accession>
    <name>A0A2S9GS52_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SMI1_KNR4 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4741</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000064">
        <property type="protein sequence ID" value="PRC90550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90550">
        <property type="protein sequence ID" value="PRC90550"/>
        <property type="gene ID" value="S2091_4741"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018958">
        <property type="entry name" value="Knr4/Smi1-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037883">
        <property type="entry name" value="Knr4/Smi1-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09346">
        <property type="entry name" value="SMI1_KNR4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160631">
        <property type="entry name" value="SSF160631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SMI1_KNR4" evidence="1">
        <location>
            <begin position="8"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="125" mass="13827" checksum="FAE64B22381A85CD" modified="2018-07-18" version="1">MSTIVNEIEKLRSAYSSLPNAYFQFLLDHDGIDCELGIDPGWVVIYPTQEALVATNQYQMSTFLPGYFAFGGNGAGEVFVFPLNRSVHECPVYMVPTVGMSVEELIEIAPSFESFAQQIGKSCED</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GS58</accession>
    <name>A0A2S9GS58_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_4738</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000060">
        <property type="protein sequence ID" value="PRC90554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90554">
        <property type="protein sequence ID" value="PRC90554"/>
        <property type="gene ID" value="S2091_4738"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003346">
        <property type="entry name" value="Transposase_20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002525">
        <property type="entry name" value="Transposase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01548">
        <property type="entry name" value="DEDD_Tnp_IS110"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02371">
        <property type="entry name" value="Transposase_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DEDD_Tnp_IS110" evidence="2">
        <location>
            <begin position="7"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="173"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC90554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="339" mass="37614" checksum="615A603C4CFBE32C" modified="2018-07-18" version="1">MENITAIGLDLAKNVFQVHGANAQGKKLVVKRLKRSEILSYFATIKPCLVGMEACGGAHQWARQLEQLGHKVKLMPPQFVKAFVQGNKTDARDAAAICEAASRDSVPTVVVRSRESQQTQSLHRVREGWMKQRVATANQIRGLLAEFGYTITPGMRRLYNEVREWQAKSGNELGILSGLIEELLAHLRQLEERISKIDQQILRVYHESSACKLIESVPGVGIMTATAIVGTFGNASMYTTGRKFACALGLTPREHNSGDKHVLLGINKRGNGYIRKLLVHGARSVLRARTGKEKYADDWAVKLAERRGHNKAACALAAKNARRIWAMLQSGEVFRTEYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSF8</accession>
    <name>A0A2S9GSF8_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7">Glutamate racemase</fullName>
            <ecNumber evidence="2 7">5.1.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">murI</name>
        <name evidence="8" type="ORF">S2091_4637</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Provides the (R)-glutamate required for cell wall biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>L-glutamate = D-glutamate</text>
            <dbReference type="Rhea" id="RHEA:12813"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:29986"/>
            <dbReference type="EC" id="5.1.1.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the aspartate/glutamate racemases family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.1.1.3" evidence="2 7"/>
    <dbReference type="EMBL" id="PUGF01000040">
        <property type="protein sequence ID" value="PRC90654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90654">
        <property type="protein sequence ID" value="PRC90654"/>
        <property type="gene ID" value="S2091_4637"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008881">
        <property type="term" value="F:glutamate racemase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00258">
        <property type="entry name" value="Glu_racemase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015942">
        <property type="entry name" value="Asp/Glu/hydantoin_racemase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001920">
        <property type="entry name" value="Asp/Glu_race"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018187">
        <property type="entry name" value="Asp/Glu_racemase_AS_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033134">
        <property type="entry name" value="Asp/Glu_racemase_AS_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004391">
        <property type="entry name" value="Glu_race"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21198:SF2">
        <property type="entry name" value="PTHR21198:SF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01177">
        <property type="entry name" value="Asp_Glu_race"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53681">
        <property type="entry name" value="SSF53681"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00067">
        <property type="entry name" value="glut_race"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00923">
        <property type="entry name" value="ASP_GLU_RACEMASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00924">
        <property type="entry name" value="ASP_GLU_RACEMASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0133">Cell shape</keyword>
    <keyword evidence="6 7" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="5 7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4 7" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="18"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="50"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="82"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="195"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="7">
        <location>
            <position position="81"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="7">
        <location>
            <position position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC90654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="286" mass="31136" checksum="B21E53471737FF78" modified="2018-07-18" version="1">MPTQTQLMSNQAPIGIFDSGIGGLSVLRHICEQLPNESLCYFADSSFAPYGDKTEAEVIQRSLYVAQHLLQLGVKAIVVACNTATTAAIAALRANYPDLILVGVEPGLKPAASLSKTGHVGVLATSRTLASSKYQLLCEQIQQTTQVRFINQACPGLVDLIEQGELDSPAALELLNNYLQPIFQAQADTIVLGCTHYPFVETSIRQIANKTSPHPIQIIDTGLAIAKQLQRLLTQQQLLNQHKTAETLHCITNGAAEKLEFALSHLLKYQPEQYIIQEISCNFPAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSJ9</accession>
    <name>A0A2S9GSJ9_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 10">Phosphoenolpyruvate synthase</fullName>
            <shortName evidence="10">PEP synthase</shortName>
            <ecNumber evidence="6 10">2.7.9.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9 10">Pyruvate, water dikinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">S2091_4618</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 10">Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>ATP + H2O + pyruvate = AMP + 2 H(+) + phosphate + phosphoenolpyruvate</text>
            <dbReference type="Rhea" id="RHEA:11364"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.7.9.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4 10">Carbohydrate biosynthesis; gluconeogenesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 10">Belongs to the PEP-utilizing enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.9.2" evidence="6 10"/>
    <dbReference type="EMBL" id="PUGF01000039">
        <property type="protein sequence ID" value="PRC90668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90668">
        <property type="protein sequence ID" value="PRC90668"/>
        <property type="gene ID" value="S2091_4618"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00138"/>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008986">
        <property type="term" value="F:pyruvate, water dikinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006090">
        <property type="term" value="P:pyruvate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008279">
        <property type="entry name" value="PEP-util_enz_mobile_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006319">
        <property type="entry name" value="PEP_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018274">
        <property type="entry name" value="PEP_util_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000121">
        <property type="entry name" value="PEP_util_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023151">
        <property type="entry name" value="PEP_util_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036637">
        <property type="entry name" value="Phosphohistidine_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002192">
        <property type="entry name" value="PPDK_AMP/ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_Kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43030">
        <property type="entry name" value="PTHR43030"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00391">
        <property type="entry name" value="PEP-utilizers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02896">
        <property type="entry name" value="PEP-utilizers_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01326">
        <property type="entry name" value="PPDK_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000854">
        <property type="entry name" value="PEP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="SSF51621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52009">
        <property type="entry name" value="SSF52009"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01418">
        <property type="entry name" value="PEP_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00742">
        <property type="entry name" value="PEP_ENZYMES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00370">
        <property type="entry name" value="PEP_ENZYMES_PHOS_SITE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0418">Kinase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PPDK_N" evidence="12">
        <location>
            <begin position="31"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="domain" description="PEP-utilizers" evidence="11">
        <location>
            <begin position="405"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="domain" description="PEP-utilizers_C" evidence="13">
        <location>
            <begin position="495"/>
            <end position="808"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001518"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00002988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00007837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00011996"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00021623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00033470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR000854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="PRC90668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="809" mass="88032" checksum="4446EB350318A465" modified="2018-07-18" version="1">MTNSNNGIAGSTLSASTYVASFENLRMHDVEVVGGKNASLGEMISQLAGAGVRVPGGFATTAQAFRDFLAFPQTDGKSLAERIANRLETLDTNDVRALAKAGAEIRQWIIDTPFQPRLMAEINEFYQKLVADSVGEMSFAVRSSATAEDLPDASFAGQQETFLNVVGIENILEAMKHVFASLYNDRAISYRVHKGFAHAEVALSAGVQRMVRSDLGAAGVMFTIDTESGFKDVVFITSSYGLGETVVQGAVNPDEFYVHKPMLASGKLPVIRRNIGSKLIKMEFTDQAKAGHSVRTVDVSIEQRNRYSLTDTEVVELAKYAVIIEQHYGRAMDIEWGKDGRDGLLYILQARPETVKSQQKATDSQQRYKLKGSGNVLVSGRAIGQKIGAGRVRVIHDPSEMELVQPGDILVADMTDPNWEPVMKRASAIVTNRGGRTCHAAIIARELGVPAVVGCGDATDILKNDTLVTVSCAEGDEGKIYDGLLETEITEVANTALPEIPVKIMMNVGNPQMAFDFQSIPNAGVGLARLEFIINNNIGVHPKAILEYPNIDPSLKKAVESVARGHASPKAFYVDKLAEGIATIAAAFWPKPVIVRLSDFKSNEYKKLIGGSRYEPDEENPMLGFRGAARYLAADFAESFEMECTAMKRVRNDMGLTNVEIMVPFVRTLGQAEKVVNLLAKNGLRRGENDLRLIMMCEVPSNAILAEQFLEFFDGFSIGSNDLTQLTLGLDRDSGMPLLAADFDERDPAVLALLSMAIAACRKQGKYVGICGQGPSDHPDFAQWLMKEGIASISLNPDSVIDTWQLLAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSM4</accession>
    <name>A0A2S9GSM4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4603</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000038">
        <property type="protein sequence ID" value="PRC90710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90710">
        <property type="protein sequence ID" value="PRC90710"/>
        <property type="gene ID" value="S2091_4603"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015559659" evidence="1">
        <location>
            <begin position="29"/>
            <end position="500"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="500" mass="51438" checksum="58D8D829386467AC" modified="2018-07-18" version="1">MRTIPNWRLRLALTLISSLVWLSLSSCSGSSSPTATSSSSGSSGTAPTPVSFASATTTFQQNMIAETPHFTNSSVVTAVNLQHYFPKHWGSIFSEAVAAELGLAVIWDPESGSAPAGSDFSVLNLYNGGGFTCSGASNTCTLGSVTIQAQESLKNFMGQALDPNFLNSNGASTTLFGRLKQASTIVCALGNLLPAAQIDTDGLPIVGSLTLSFPAATTNIIYQPISAGGCSAPTDQAGASLPLTVTAVTSANYAKQIIIAPLSVIAWLKLDTTAGSLNVMTLEDQRNNGRYAVDRAIANITGINTPGSGKTLFEYISIGSNVAGSTNCYANGGWQCSYEYHRVFIDEAANGAYLVSNFGSPGDQSGGIGTPTSFLQYTAVARPSDLKTCTSGGTCSGSLALSFTANGQQEVNSNIVYPSVGNDYEGCVNLLDRSLASSGALTCSITGTSILASGGASAMIESTRQVYATDVVATLLAHTSATTTLSFTGATDIFTAPNTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSP2</accession>
    <name>A0A2S9GSP2_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF2726 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_4542</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000037">
        <property type="protein sequence ID" value="PRC90716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90716">
        <property type="protein sequence ID" value="PRC90716"/>
        <property type="gene ID" value="S2091_4542"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024402">
        <property type="entry name" value="DUF2726"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10881">
        <property type="entry name" value="DUF2726"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="domain" description="DUF2726" evidence="2">
        <location>
            <begin position="37"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC90716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="151" mass="16887" checksum="0BA279674C12D95D" modified="2018-07-18" version="1">MINPLVIAVGVIIIGGILTLAASKKTGKNKTYSYKAKKLFTNNEKEMHSKLTKTFPEYKIFSQVALSSMIEGKNFASHGTISRMSVDFVILDQELNIVSAIEIDDKSHQREDRKKADATKNEAFKQAGIKLIRWPAVPHPNEIQMLKDVKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSQ3</accession>
    <name>A0A2S9GSQ3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Response regulator of the LytR/AlgR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_4561</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000037">
        <property type="protein sequence ID" value="PRC90735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90735">
        <property type="protein sequence ID" value="PRC90735"/>
        <property type="gene ID" value="S2091_4561"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007492">
        <property type="entry name" value="LytTR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04397">
        <property type="entry name" value="LytTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00850">
        <property type="entry name" value="LytTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50930">
        <property type="entry name" value="HTH_LYTTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="9"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="HTH LytTR-type" evidence="3">
        <location>
            <begin position="134"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC90735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="250" mass="28580" checksum="E2A34F39DE0E8BDA" modified="2018-07-18" version="1">MDNCSTPLRALIVDDEPLARSNLAVLLARDAGIVLVGQCGSAEDALATIPIIKPNLVFLDVEMPECDGFELLERIGPSLDFAIVFVTAHHQFALRAFEVGALDYLLKPFDDQRFERVLERVKERLRIPGETQRFIIKNGNTLEVVKFLDIDWIEASDYYSTLHTGDRTHMLRRSLADLEQLLAPLGFCRIHRSAIVNLDRVRALEIREDGEYEIVLQCAQRVRMSRRYRKPILEQLEGQPGVRFFSQKDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GT34</accession>
    <name>A0A2S9GT34_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4372</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000033">
        <property type="protein sequence ID" value="PRC90879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90879">
        <property type="protein sequence ID" value="PRC90879"/>
        <property type="gene ID" value="S2091_4372"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021295">
        <property type="entry name" value="DUF2867"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11066">
        <property type="entry name" value="DUF2867"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC90879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="171" mass="18787" checksum="B03759550CF94B78" modified="2018-07-18" version="1">MTNKVLLIPAPTAAIRASGLSHIDFADGYSGQADRTYVDAAQAARAAFADPPHMARCLMTLRNRIVAPFGLRASIDFSDRGMGKIDVFPIISNTGAEVVVGGDDKHLDFRIWISIQPSLKGSEVTISTLVKINSLFGRVYLCTIMPFHKLLSRMMLQRAINRRDNVPSEAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GT75</accession>
    <name>A0A2S9GT75_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Antirepressor regulating drug resistance predicted signal transduction N-terminal membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_4394</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000033">
        <property type="protein sequence ID" value="PRC90901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90901">
        <property type="protein sequence ID" value="PRC90901"/>
        <property type="gene ID" value="S2091_4394"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008756">
        <property type="entry name" value="Peptidase_M56"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05569">
        <property type="entry name" value="Peptidase_M56"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="90"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="273"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M56" evidence="2">
        <location>
            <begin position="8"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC90901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="407" mass="45116" checksum="2FD0B8DF55DE1237" modified="2018-07-18" version="1">MSNELIPTLIQTTIALTVALLLALLLRTVLRRQFGAPHGYAVWLLVPLLPLTCLLPLLIPRANLPLPALHLPAFTTNAIALAPTSTIDTALLITALWIIGILFSLGLLYWRQMQFMRSLGRIEKIGDIYTAQAHDICPALVGILRPKIVVPGDFASRYTAIEQVLILAHERQHRQRGDNWANAMCALLQSVFWFHPLIHFCAARFRFDQELACDALVIRHHRNARKTYANAMLKTKSLQFDVPVACTWQSRHFLKERIMQINVNTPHSMKRHIGSALLITLITLGTCVTWAAQSTPTKERDKKGYDVTTTVTTEDGKATNSTIHVLTGESFALVGGAADKWSGTVKLTAPNEKSVKFEVTLAQADKIIGHPILISHNDEIAKIEYGNGSSKFTMDIKAKPTATTSPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTC1</accession>
    <name>A0A2S9GTC1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4356</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000032">
        <property type="protein sequence ID" value="PRC90955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90955">
        <property type="protein sequence ID" value="PRC90955"/>
        <property type="gene ID" value="S2091_4356"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015733925" evidence="1">
        <location>
            <begin position="28"/>
            <end position="700"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="700" mass="75249" checksum="EAE31760B6B1DB8A" modified="2018-07-18" version="1">MNAASLFVSLVLLLGWCDASSAAPASAVSSADDGVPITSIKIQNASKGATHDSVATPITFGQVFAAGDVPDPNALVGRLADGTHIPLQVDAKARHPDGSLRHAVISAVVPVPSGSSITVLSLNKVTAPTAKASGIGPEALLGNGFSASVNLTLDGQVYSASANDLLRSGKYINWLAGPQVNEWEVSAPLKTAQGVAHPNLSARFAIRSYTGINSASVDVTVENDWAFAPAPQNVTYDVQVLVGGKVVYTKSALKHFHHARWRKVFWWGTEPQVNLQHDSAYLISTKALPNYDQSLKIAASTLNNIGVRFSGMATEPMGNGLAVPYMPTTGGRGDIGLLPSWAVSYLLSMNPVAKKATLGTADLSGSWSMHYRNQKTNRPVSLVDFPYMTLVGNPSDTFNPATKRSEAFPACGGDCVTPYSADPAHEPALAYLPYLVTGDYYYLEELQFWAMFDLFESNPGYRANIKGLFHQTQVRAQAWTLRDLANAAYITPDADVLKKQFETALSDNLDWYNSAYKPKASLDNAFGALTDINARQYNNFTGIAPWQDDFFTSAVGHTVELGYAKAKPLLAWKAQFPIKRMIDPAYCWIVGAVYAFQVTDTNGGPIYTDMAKAYQTSNPQALTALPCGGTEMAYFLKLKVGEMTGHSSEPDGFPSNMQPALAYSVYSGAAGGADAWKVFMARSIKPDYSTSPQFAILPRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTC5</accession>
    <name>A0A2S9GTC5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">YD repeat (Two copies)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_4368</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000032">
        <property type="protein sequence ID" value="PRC90967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90967">
        <property type="protein sequence ID" value="PRC90967"/>
        <property type="gene ID" value="S2091_4368"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045351">
        <property type="entry name" value="DUF6531"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031325">
        <property type="entry name" value="RHS_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006530">
        <property type="entry name" value="YD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20148">
        <property type="entry name" value="DUF6531"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05593">
        <property type="entry name" value="RHS_repeat"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01643">
        <property type="entry name" value="YD_repeat_2x"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015697253" evidence="1">
        <location>
            <begin position="21"/>
            <end position="844"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6531" evidence="2">
        <location>
            <begin position="154"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC90967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="844" mass="90061" checksum="7BC36C810D6042FA" modified="2018-07-18" version="1">MKKLLFIFLFLIFNSELSYSQTSYSQTFAATAVFSGPATVSTLAAFTSYCLNTYTPEQLHGATLSVDMQPYIPNTTYVFYYCMINGNGNPPKWFLFAGDFYFSCPNYDVIVLGQDGFNSTCVCPPNNLYFGDVQKCVPVIQVPPPKKDCGCKVGDPIGVGTGNSVQTQIDLTVATPLSGLTTARTYNSAPGNPDGQMLRSFGARWTQPYDVSIVPMGVVTPTNPVTYNFPAICWERTDTNYIWCDYPKYIASPLQQIVEVVRGGGQGLYFTSAPGGPVNGTMTWFADSDVSGQLTSTVASNGTTMTGYTFTDTDNHKETYDGNGVLLSISAQGGSTQQLTYSTGVSNDSSVGRYPATAPICPHVQAGAVVNGGTLLCVTDQWGRQLQYEHDSLGRITETIDPNNQLTQYAYDGPSAGCTAANTVSSLACSANNLTAIIYPDGKTKTLYYNEAAQINGGTVCPNSAPVGNGFSYLLNALTGIVDENGNRSVSWTFNCSGVATSSQLGAGVDNYQIAVGTPNANGSGTSTVTTPLGAQVTYGFTPINSLVVSNTITQPAGSGSGVATATSTYDANSNVLSYTDFNGNVTTYTYDMARNLELTKVDAAGTAQQRTSTTVWNPTYRLPAQVAEPLRLTTYTYDMNGNLLSKTQQATSDANGSQGLSATVIGAPRTWKYTYNSVGQVLTITGPRTDVTDLTQFAYDTYGNLSSVTNAAGQITTLSNYDLNGHVGSITDPNGLTTTYVYSPRGWLTSQSRGSEVTSYNYDGAGQLLSATFPNQAKLNYTYDAAHRLTNIADNLGNTVNYTLDAMGNRTLEQVNDASGNLTRQISRVVDALNRLQQITGAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTE0</accession>
    <name>A0A2S9GTE0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Acyltransferase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_4359</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000032">
        <property type="protein sequence ID" value="PRC90958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90958">
        <property type="protein sequence ID" value="PRC90958"/>
        <property type="gene ID" value="S2091_4359"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002656">
        <property type="entry name" value="Acyl_transf_3_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01757">
        <property type="entry name" value="Acyl_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="125"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="208"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="238"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="303"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="330"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl_transf_3" evidence="2">
        <location>
            <begin position="9"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC90958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="379" mass="42790" checksum="C5DE3284CD6084B7" modified="2018-07-18" version="1">MKPHNRISSLESSRGLLALWVVVGHVLRHAGYREQDLGIAKFLVEPGLAVDVFIMISGFVIFFLLDQQRTSTLHFLVRRWFRLMPVFLFVLIASALTLNWQLNVISTTPWQGDAVMNDLAIHLDTAKYFVAHLLAHITLLHGLISDHILPNSQYAFIGQAWSISVEWQFYLVAPFIFHAVIAKKWNTVASLLIAVCVLRSLNYSGEGFAVNQAGYFLIGMLSYFIWKRADQLSAIDFRLIEVAALVLIALSYFLIVRSLSPVLWIALMTCMLAEQHDSPGLVQQYLGRLLNHPLLRWCGKISYSVYMVHMLVIYAIQYSILTMWPHIEKIYFVALMLPLAVAGTLGLAVFSWTFIEAPGIELGRRVSAYVKVPAPTVIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTE4</accession>
    <name>A0A2S9GTE4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4285</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000031">
        <property type="protein sequence ID" value="PRC90989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90989">
        <property type="protein sequence ID" value="PRC90989"/>
        <property type="gene ID" value="S2091_4285"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC90989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="85" mass="9783" checksum="15E72D231ABB0E21" modified="2018-07-18" version="1">MTTIVELSLANDKVYTMTTTQQKQPKQLRVQRGILGGPLNLRLTPDEMIRVEKYAADEFRSRASFLRVMILAGLEQYERNIAINQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTF0</accession>
    <name>A0A2S9GTF0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">O-antigen ligase like membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_4295</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000031">
        <property type="protein sequence ID" value="PRC90999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90999">
        <property type="protein sequence ID" value="PRC90999"/>
        <property type="gene ID" value="S2091_4295"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007016">
        <property type="entry name" value="O-antigen_ligase-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021797">
        <property type="entry name" value="Wzy_C_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04932">
        <property type="entry name" value="Wzy_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11846">
        <property type="entry name" value="Wzy_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0436">Ligase</keyword>
    <keyword evidence="2 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="34"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="65"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="91"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="120"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="164"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="199"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="242"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="283"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="337"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="417"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="domain" description="Wzy_C_2" evidence="5">
        <location>
            <begin position="369"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="560"/>
            <end position="582"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF11846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC90999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="582" mass="66483" checksum="7A59DD1ADA5C3C92" modified="2018-07-18" version="1">MLNNKQLNYVIGIFAFFLFCSYIHPFHIHPYRNYYHDALTITALVFGIGFLSFSPKLTIQIPSAVFLPIGMIIIIALQTWNGFLLMPMDSFFPIVELFCFILAIIFGATLVRHLQGMEKLCFAFSCVFVVTSLLSVVFQHIQIAGLNAMPFVMPTNVNGIVSRLYANLAQPNLLALLMCFSLASVWWMYQSSRLNKSMAISIVMIVLWGLTLTQSRIAWIILPLFVLACWFHPRDCKLVDRHVLVFLLFLFALMVVFAPSFLSYVGYHSFETAAQRAGHNERLILWHQAWVMSLMHPWFGVGWLQFGQYQVALSPLFEPVGMSDYAHNFVLNLAAELGWPATLLIVASTVYWFYVSCLKYWRNVHIRYLSLMFCAVAVHSMVEFPLWNAYILIPFGVMVGAAHGSNLGGLQFGCVRSWIISFFVAALLAIGAVSWDYHRVVDGFQALYWEQMGSTKGKGGTDKPEFTLFPQFYDYFRIDKIKIYTGMPAQDITFLEKMSLSFGFPPVLERLALAYALNQRATEALQVMTANQRLNQNYYPKSYALWAKYAEQDPRNFSEIFKRMPKPDSANKPETESTSSKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTG5</accession>
    <name>A0A2S9GTG5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4303</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000031">
        <property type="protein sequence ID" value="PRC91007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91007">
        <property type="protein sequence ID" value="PRC91007"/>
        <property type="gene ID" value="S2091_4303"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021312">
        <property type="entry name" value="DUF2889"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11136">
        <property type="entry name" value="DUF2889"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="198" mass="21855" checksum="5F9C68E0125CB80E" modified="2018-07-18" version="1">MFFSPPNSRRALKHSRVIEIDAYAREDSLWDIEARIRDTKTSDTQLASGLRPAGMPIHDLGLRICINTQFDIVDAEAVSSAHPYPGYCNAITPDYTKLVGLNLLKQFRHEVKVRLGGTRGCTHLTELAQVLPTAALQAFAGEVLKTHEVGGGEVKNAINATVQDNQQQPFQLDRCHALKLDSGAVATYYPRWVKQASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTI3</accession>
    <name>A0A2S9GTI3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Putative integral membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">S2091_4307</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TMEM175 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000031">
        <property type="protein sequence ID" value="PRC91011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91011">
        <property type="protein sequence ID" value="PRC91011"/>
        <property type="gene ID" value="S2091_4307"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005267">
        <property type="term" value="F:potassium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010617">
        <property type="entry name" value="TMEM175"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06736">
        <property type="entry name" value="TMEM175"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0407">Ion channel</keyword>
    <keyword evidence="9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0630">Potassium</keyword>
    <keyword evidence="6" id="KW-0631">Potassium channel</keyword>
    <keyword evidence="4" id="KW-0633">Potassium transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="9"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="39"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="70"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="105"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="148"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006920"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PRC91011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="193" mass="21667" checksum="678FE352E1DFA7A2" modified="2018-07-18" version="1">MEKGRLEAFSDGVIAVIITIMVLELHVPHGNQLADLVPLLPKFLCYVLSFINVGLYWNNHHHLMQAAKHVNGRILWANLHVLFWMSLIPVTTDWMGENHFAQTPVILYGVVLLMCGVAYSFLVKALIAKHGKDSVLAQAIGRDKKGNISVLLYALAIALAFISSWIAMGLYLTVAAMWLIPDTRFEKIIYQKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTK9</accession>
    <name>A0A2S9GTK9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4229</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000030">
        <property type="protein sequence ID" value="PRC91041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91041">
        <property type="protein sequence ID" value="PRC91041"/>
        <property type="gene ID" value="S2091_4229"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="39" mass="4347" checksum="E0A6BD6212EDD4A4" modified="2018-07-18" version="1">MKGLSRSNLMYMRAFANAWPAKVIVQEVLGQLPRVNEGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTL6</accession>
    <name>A0A2S9GTL6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">6-phosphogluconate dehydrogenase (Decarboxylating)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_4243</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Carbohydrate degradation; pentose phosphate pathway.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the 6-phosphogluconate dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000030">
        <property type="protein sequence ID" value="PRC91055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91055">
        <property type="protein sequence ID" value="PRC91055"/>
        <property type="gene ID" value="S2091_4243"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00115"/>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004616">
        <property type="term" value="F:phosphogluconate dehydrogenase (decarboxylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019521">
        <property type="term" value="P:D-gluconate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016054">
        <property type="term" value="P:organic acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006098">
        <property type="term" value="P:pentose-phosphate shunt"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002204">
        <property type="entry name" value="3-OH-isobutyrate_DH-rel_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004849">
        <property type="entry name" value="6DGDH_YqeC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006114">
        <property type="entry name" value="6PGDH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006115">
        <property type="entry name" value="6PGDH_NADP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006183">
        <property type="entry name" value="Pgluconate_DH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11811">
        <property type="entry name" value="PTHR11811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00393">
        <property type="entry name" value="6PGD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03446">
        <property type="entry name" value="NAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00076">
        <property type="entry name" value="6PGDHDRGNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01350">
        <property type="entry name" value="6PGD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00872">
        <property type="entry name" value="gnd_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00895">
        <property type="entry name" value="3_HYDROXYISOBUT_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0311">Gluconate utilization</keyword>
    <keyword evidence="4" id="KW-0520">NAD</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="6PGD" evidence="6">
        <location>
            <begin position="184"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004959"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC91055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="337" mass="36487" checksum="587D991958E33B0E" modified="2018-07-18" version="1">MQIGMIGLGRMGANMVRRLADGDHNCIVYDVQDSAIQALVHHNVAGATSISDLVSQLDQPRVIWLMVPAAIVDESLKTLVPLLSSGDIIIDGGNSYYHDDIRRGNELKLHKIHYLDVGTSGGVAGLDRGYCLMIGGEKEIVQHLSPIFETLAPGVDAAPLTVGRTNRSSTADHGYLHCGPQGAGHFVKMVHNGIEYGIMGAYAEGLNILHHANIGKSKVDSDAETTPLRNPEHYQYELDLTEITELWRRGSVIGSWLLDLTAAALVKDPKLENYTGRVSDSGEGRWTIMAAIDEAVPIPILSAALFERFSSRGAADFSDKLLSAMRHGFGGHIEKSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTU4</accession>
    <name>A0A2S9GTU4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Hpt domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_4130</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000028">
        <property type="protein sequence ID" value="PRC91129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91129">
        <property type="protein sequence ID" value="PRC91129"/>
        <property type="gene ID" value="S2091_4130"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00088">
        <property type="entry name" value="HPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036641">
        <property type="entry name" value="HPT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008207">
        <property type="entry name" value="Sig_transdc_His_kin_Hpt_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01627">
        <property type="entry name" value="Hpt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00073">
        <property type="entry name" value="HPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47226">
        <property type="entry name" value="SSF47226"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50894">
        <property type="entry name" value="HPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HPt" evidence="3">
        <location>
            <begin position="1"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="138"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="modified residue" description="Phosphohistidine" evidence="1">
        <location>
            <position position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC91129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="298" mass="32777" checksum="B683EF375F52EF7F" modified="2018-07-18" version="1">MNRDQPLQTFIIESRELLAAMDTALLTVEHAKNQTDMVKTIFRTAHIIKGSASLFGLDHIAAFSQLIENVLELVREDKIGIADRMVTLLSSCSNYIGTMVDAAEAGQLEPDQAMSQRGLLLSEQLQLYLGASISTSTPALTTAQPRPSGAIRKPSGNADKESGYWQISLRFGPDVLRNGMEPLSFIRYLAKLGTIAGIVTLIDAVPDSEKMNPESCYLGFEITLSSAADQATIENVFEFLRDDCSIQLLTPQSHVSDYIQLIQRMPEQAERLGTILIRCGIITRQELTGALHVTHELL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTX8</accession>
    <name>A0A2S9GTX8_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Methylated-DNA--protein-cysteine methyltransferase</fullName>
            <ecNumber evidence="7">2.1.1.63</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">6-O-methylguanine-DNA methyltransferase</fullName>
            <shortName evidence="7">MGMT</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">O-6-methylguanine-DNA-alkyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">S2091_4212</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>a 4-O-methyl-thymidine in DNA + L-cysteinyl-[protein] = a thymidine in DNA + S-methyl-L-cysteinyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:53428"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:10132"/>
            <dbReference type="Rhea" id="RHEA-COMP:13555"/>
            <dbReference type="Rhea" id="RHEA-COMP:13556"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:82612"/>
            <dbReference type="ChEBI" id="CHEBI:137386"/>
            <dbReference type="ChEBI" id="CHEBI:137387"/>
            <dbReference type="EC" id="2.1.1.63"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 7">
            <text>a 6-O-methyl-2'-deoxyguanosine in DNA + L-cysteinyl-[protein] = a 2'-deoxyguanosine in DNA + S-methyl-L-cysteinyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:24000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:10132"/>
            <dbReference type="Rhea" id="RHEA-COMP:11367"/>
            <dbReference type="Rhea" id="RHEA-COMP:11368"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:82612"/>
            <dbReference type="ChEBI" id="CHEBI:85445"/>
            <dbReference type="ChEBI" id="CHEBI:85448"/>
            <dbReference type="EC" id="2.1.1.63"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="7">This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the MGMT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.63" evidence="7"/>
    <dbReference type="EMBL" id="PUGF01000029">
        <property type="protein sequence ID" value="PRC91116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91116">
        <property type="protein sequence ID" value="PRC91116"/>
        <property type="gene ID" value="S2091_4212"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003908">
        <property type="term" value="F:methylated-DNA-[protein]-cysteine S-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006307">
        <property type="term" value="P:DNA dealkylation involved in DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06445">
        <property type="entry name" value="ATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00772">
        <property type="entry name" value="OGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001497">
        <property type="entry name" value="MethylDNA_cys_MeTrfase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014048">
        <property type="entry name" value="MethylDNA_cys_MeTrfase_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036217">
        <property type="entry name" value="MethylDNA_cys_MeTrfase_DNAb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008332">
        <property type="entry name" value="MethylG_MeTrfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023546">
        <property type="entry name" value="MGMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036631">
        <property type="entry name" value="MGMT_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01035">
        <property type="entry name" value="DNA_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02870">
        <property type="entry name" value="Methyltransf_1N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46767">
        <property type="entry name" value="SSF46767"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53155">
        <property type="entry name" value="SSF53155"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00589">
        <property type="entry name" value="ogt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00374">
        <property type="entry name" value="MGMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6 7" id="KW-0234">DNA repair</keyword>
    <keyword evidence="4 7 10" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_1N" evidence="9">
        <location>
            <begin position="6"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="domain" description="DNA_binding_1" evidence="8">
        <location>
            <begin position="85"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile; methyl group acceptor" evidence="7">
        <location>
            <position position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC91116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="166" mass="18645" checksum="86B62BEEA8FF3E6E" modified="2018-07-18" version="1">MNTIIHYKEHPSPLGQLTLAATPQGICGIYFEDQRNFNDIKDKQNWQHTEHHQHLDKATHQLDEYFAGQRQHFDVQLDLHLRGTEFQQAVWQALLSIKFGKTSSYGAHAKLINKPLAVRAVGGAIGRNPISIIVPCHRVLGGNGTLTGYDGGLDRKKYLLQLEGVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTZ5</accession>
    <name>A0A2S9GTZ5_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Potassium-transporting ATPase potassium-binding subunit</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">ATP phosphohydrolase [potassium-transporting] A chain</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Potassium-binding and translocating subunit A</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Potassium-translocating ATPase A chain</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">kdpA</name>
        <name evidence="10" type="ORF">S2091_4075</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">The system is composed of three essential subunits: KdpA, KdpB and KdpC.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the KdpA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000027">
        <property type="protein sequence ID" value="PRC91180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91180">
        <property type="protein sequence ID" value="PRC91180"/>
        <property type="gene ID" value="S2091_4075"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008556">
        <property type="term" value="F:P-type potassium transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030955">
        <property type="term" value="F:potassium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00275">
        <property type="entry name" value="KdpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004623">
        <property type="entry name" value="KdpA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30607">
        <property type="entry name" value="PTHR30607"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03814">
        <property type="entry name" value="KdpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001294">
        <property type="entry name" value="K_ATPaseA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00680">
        <property type="entry name" value="kdpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9" id="KW-0630">Potassium</keyword>
    <keyword evidence="3 9" id="KW-0633">Potassium transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="66"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="137"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="177"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="286"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="314"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="372"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="399"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="424"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="464"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="528"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="571"/>
            <end position="593"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC91180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="607" mass="64071" checksum="0B64A8DD992EDDD5" modified="2018-07-18" version="1">MNSSIHFQLALFLIVLMLCAVPLGGYIARIMSGEGNAVTRLIGPIERFIYRICGVDHNTEMGWKSYAFAVILFNLLGVLAVYALQRLQGFLPLNPQAMAAISPDSSFNTAISFVTNTNWQGYTGEAAMSYLTQMLGLAVQNFFSAATGLAVVIAMIRGFARHSMQTIGNFWVDITRSVLYILLPLALIIAVFFMGQGVIQNFDEYKTVNLTEALTYTQPKVDAAGAPVLDAKGVAVQETLTTTTQTLPMGPVASQEAIKMVGTNGGGFFNANSAHPYENPTPLSNFIQILAIFLIPAALCIAFGKMVGDPRQGWAVLAAMTVIFVVMAYFANAAEMQGNPALNGMGIDQTAQVSSGNFAQAGGNMEGKETRFGIVASSIFATVTTAASCGAVNGMHDSFTALGGMVPLWLIQLGEVVFGGVGSGLYGMLIFAILAVFIAGLMIGRTPEYLGKKIEAFDMKMVSIAILVGPFLVLVGTAIAVLVTDGKAGILNPGAHGFTEVLYAFSSAVNNNGSAFAGISANTPFYNIMLAIAMWFGRFLVIVPVLAIAGSLVRKKRLATTVGSLPTHGPLFVVLLIGSVIIVGALTYIPALALGPVIEHLTLSAGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GU25</accession>
    <name>A0A2S9GU25_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4105</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000027">
        <property type="protein sequence ID" value="PRC91210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91210">
        <property type="protein sequence ID" value="PRC91210"/>
        <property type="gene ID" value="S2091_4105"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="33" mass="3697" checksum="D03D5B96795D09FB" modified="2018-07-18" version="1">MDLLKLKIIITLPIKAEADVVKLKMGVSENRCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUB1</accession>
    <name>A0A2S9GUB1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="9">ATPase components of ABC transporter with duplicated ATPase domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_3993</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000025">
        <property type="protein sequence ID" value="PRC91322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91322">
        <property type="protein sequence ID" value="PRC91322"/>
        <property type="gene ID" value="S2091_3993"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032781">
        <property type="entry name" value="ABC_tran_Xtn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12848">
        <property type="entry name" value="ABC_tran_Xtn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-1278">Translocase</keyword>
    <feature type="domain" description="ABC transporter" evidence="8">
        <location>
            <begin position="1"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="8">
        <location>
            <begin position="308"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="75"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="565"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="25"/>
            <end position="32"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="348"/>
            <end position="355"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC91322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="637" mass="71070" checksum="BB0F8CEF0E55EC4A" modified="2018-07-18" version="1">MRGTKPLFEGVDLTLNPREKIGLIGSNGAGKSSLFAMLRNEIHSDQGSLDFPAQWQVAYVAQETPALERSAIDYAIDGDTRLRKLETKLAELEEQEATDENGNLIAEVYIALADADAYTVQSRAEQLLLGLGFTMAQMTQSVASFSGGWRMRLNLAQALMCPSDLLLLDEPTNHLDLDAIIWLEEWLKRYAGTLVIISHDRDFLDGVVNVIVHIDERKLKRYGGNYSSFERQRLAQLVLAQGLIEKQNRQRAHLISFIDRFKAKASKAKQAQSRVKALARMDELAPLRAAAEFSFEFKEPLNAPNPLLVLEDVSAGYHLDEYDLSKTKIIVDNINFSLQIGQRIGLLGVNGAGKSTLIKTIAGELNPVNGVAHIGKGLTIGYFAQHQVEMLRHDESPLWHLIKIAPNVREQELRNFLGSFNFPGQMVTSPIKPFSGGEKARLALALIVWQRPNLLLLDEPTNHLDLETREALTDALAQFEGTVVLVSHDRHLLRATTDQFIIVADGELKPFDGDLDDYKDWLLQNKLATAEAAKKHVATSVAAQVSQPTIENKPVKISSLNPTQKKALEAKVKRLDEEIEKFNRELTAFASKLEGGDMYEEKRKEELKALLALQATTQKNLELAESEWLSLNEQLEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUG3</accession>
    <name>A0A2S9GUG3_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Tautomerase</fullName>
            <ecNumber evidence="3">5.3.2.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_3886</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the 4-oxalocrotonate tautomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.2.-" evidence="3"/>
    <dbReference type="EMBL" id="PUGF01000024">
        <property type="protein sequence ID" value="PRC91341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91341">
        <property type="protein sequence ID" value="PRC91341"/>
        <property type="gene ID" value="S2091_3886"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006725">
        <property type="term" value="P:cellular aromatic compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.429.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004370">
        <property type="entry name" value="4-oxalocrotonate_tautomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014347">
        <property type="entry name" value="Tautomerase/MIF_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018191">
        <property type="entry name" value="Tautomerase_Pseudo-typ"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01361">
        <property type="entry name" value="Tautomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55331">
        <property type="entry name" value="SSF55331"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00013">
        <property type="entry name" value="taut"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tautomerase" evidence="4">
        <location>
            <begin position="2"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; via imino nitrogen" evidence="2">
        <location>
            <position position="2"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR618191-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU362032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC91341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="67" mass="7419" checksum="711A6E59B20FC7AE" modified="2018-07-18" version="1">MPYVNFKITREGATAEQKAALIKGVTQLLVDILGKNPQTTFVTIDEVDTDNWGIAGETVTVRRRDGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUS0</accession>
    <name>A0A2S9GUS0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">LTXXQ motif family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_3868</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CpxP/Spy family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000023">
        <property type="protein sequence ID" value="PRC91453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91453">
        <property type="protein sequence ID" value="PRC91453"/>
        <property type="gene ID" value="S2091_3868"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012899">
        <property type="entry name" value="LTXXQ"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07813">
        <property type="entry name" value="LTXXQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0574">Periplasm</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015766702" evidence="5">
        <location>
            <begin position="20"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC91453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="166" mass="17830" checksum="647571C9B2DE31D5" modified="2018-07-18" version="1">MKKYITALVSTLLISGAYAQTPAVTAGAAASVPVSASAPASPASMAKSDAKRDQANEKHIKELHTKLKITKEQETLWDTVAKTMRDSANEIDKVIDKRESLIPSATAIDDLNAYADIAQAHADSVKKLSMVFGPLYAAMSDTQKKEADEIFTQRGHAGKDQRISAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUT4</accession>
    <name>A0A2S9GUT4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3751</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000022">
        <property type="protein sequence ID" value="PRC91473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91473">
        <property type="protein sequence ID" value="PRC91473"/>
        <property type="gene ID" value="S2091_3751"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007402">
        <property type="entry name" value="DUF455"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011197">
        <property type="entry name" value="UCP012318"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04305">
        <property type="entry name" value="DUF455"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF012318">
        <property type="entry name" value="UCP012318"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="SSF47240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="285" mass="31864" checksum="481D4782509D1ADE" modified="2018-07-18" version="1">MLQMPTEIPQEFTHELRHLALNALELTDPTQKVAQTQVLYEKQQAGHIALDIHHQFAAHAGAQIPGRPEKPELVPPLQVKRRTMRTPEGRAILLHALCHIEFNAINLALDAIWRFPGMPADYYVDWLKVAAEEALHFSLLAEHLTTLGYAYGDFPGHDTLWEMVAKTQEDVLARMALVPRTMEARGLDAAPSTRNKLAQVGDDAGAAIIDIILRDEIGHVAIGNRWFAYLCLQRDLEPIACYASLAERYAAPKLRAPFNLDARRAAGFTEAELQALQDSTERTQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUX6</accession>
    <name>A0A2S9GUX6_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Alanine racemase</fullName>
            <ecNumber evidence="3">5.1.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_3791</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>L-alanine = D-alanine</text>
            <dbReference type="Rhea" id="RHEA:20249"/>
            <dbReference type="ChEBI" id="CHEBI:57416"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="EC" id="5.1.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 3 4">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the alanine racemase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.1.1.1" evidence="3"/>
    <dbReference type="EMBL" id="PUGF01000022">
        <property type="protein sequence ID" value="PRC91513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91513">
        <property type="protein sequence ID" value="PRC91513"/>
        <property type="gene ID" value="S2091_3791"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00042">
        <property type="reaction ID" value="UER00497"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008784">
        <property type="term" value="F:alanine racemase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030632">
        <property type="term" value="P:D-alanine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.37.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01201">
        <property type="entry name" value="Ala_racemase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000821">
        <property type="entry name" value="Ala_racemase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009006">
        <property type="entry name" value="Ala_racemase/Decarboxylase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011079">
        <property type="entry name" value="Ala_racemase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001608">
        <property type="entry name" value="Ala_racemase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020622">
        <property type="entry name" value="Ala_racemase_pyridoxalP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029066">
        <property type="entry name" value="PLP-binding_barrel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00842">
        <property type="entry name" value="Ala_racemase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01168">
        <property type="entry name" value="Ala_racemase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00992">
        <property type="entry name" value="ALARACEMASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01005">
        <property type="entry name" value="Ala_racemase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50621">
        <property type="entry name" value="SSF50621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51419">
        <property type="entry name" value="SSF51419"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00492">
        <property type="entry name" value="alr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00395">
        <property type="entry name" value="ALANINE_RACEMASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3 4" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ala_racemase_C" evidence="6">
        <location>
            <begin position="238"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; specific for D-alanine" evidence="3">
        <location>
            <position position="35"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; specific for L-alanine" evidence="3">
        <location>
            <position position="259"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3 5">
        <location>
            <position position="131"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3 5">
        <location>
            <position position="307"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="3 4">
        <location>
            <position position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR600821-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR600821-52"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC91513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="363" mass="39088" checksum="F80F129091FE3F21" modified="2018-07-18" version="1">MPRPITATIHLSALTHNYAIARQHGGAAKIWAVVKANAYGHGLAFARQAFDGADGLALVEVDYAVKLREMGWNKPIMLLEGFFHASDLPLVQQHQIDIAVHCFEQIELLEKANLSADVIKVHLKVNGGMNRLGFQPADIPAAYQRLCAIQAVRVVELMMHFANADDEFNPRLPVAEQLRRFEVAQASLGEVKLEISLSNSAANLLNTSIRESWVRAGIMLYGGSPSSAAAADFGLLPGMTLRSELIAIQEIQAGDAVGYGSRFVASKPMRIGVVACGYADGYPRHAVDGTPVLVSGVRTCLVGRVSMDMITVDVTDVADARVGSEVVLWGRGLPIDEVAFAAGTIGYELMCAVAQRVQLIVED</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUY1</accession>
    <name>A0A2S9GUY1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3820</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000022">
        <property type="protein sequence ID" value="PRC91542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91542">
        <property type="protein sequence ID" value="PRC91542"/>
        <property type="gene ID" value="S2091_3820"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="133" mass="14589" checksum="406828CB61506859" modified="2018-07-18" version="1">MHTPFPETHQRPWLALNGVDEAEIWVANSNLELNYFLEQEQNSGLPIGQGICFALELGGELFLHTTSEGILLLDVTEAAEWVVPIIAACTGAAPARGQIWILPEDTLIQLILGLNSLIASSSIVLRHDFGMHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GV04</accession>
    <name>A0A2S9GV04_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">TPR repeat</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3764</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000022">
        <property type="protein sequence ID" value="PRC91486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91486">
        <property type="protein sequence ID" value="PRC91486"/>
        <property type="gene ID" value="S2091_3764"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004027">
        <property type="entry name" value="SEC_C_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02810">
        <property type="entry name" value="SEC-C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="119"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="153"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="187"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="255"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="612" mass="68397" checksum="B96664430BBABAF0" modified="2018-07-18" version="1">MDNKSNQGALMMKKMGRNDLCACGSGKKYKNCCMAKELLHASANQQEAQWIASAIETAITHHQQGQQKEAQEIYEAILQIEPDHAHALHFLGVIAYQNKQYPIAEDLMSRSIAANPLVAMYYCNYGMLLKDLGKFAQAVENHRKALALQADYAEAHLNLGVALFNLELYDEASESFRKTIQLQPGSAKAFDNLGTVLRCQYDFANAIQCYQRALELDPNYVISYSNLAATYIEVKNFPMASSYCLKAIALDQNCADAYMYLGIACQEQGDLAGAEKFLHHAAALAPQNFNTHWNISITMLALGKLDQGWKGYEFRWIRGTGPVKQHHFPYPWWQGEVMPDKTILIWGEQGIGDEIMFANMIEDLIPRFKQCIIACNKKLLPLFSRSFPAAKIVAINDVQQLSELSNVIDVQSAAGSLARWLRPTIASFPKKTHYLEPNADRVADWKERLAALGPELTVGICWRSGNMVGNRPLYCTQLDQWGPIFATPGVRFINLQYDECSAELEAAKHAFGIEIHSFAEVDLFNDLDEAAALTKALDLVISAPTSAAILAAALGVPTWMMISGFEWQTLGTSEICWYSTARIFHKPWEQEWDTVIANVATQLQLKRVEGSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GV25</accession>
    <name>A0A2S9GV25_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">FAD/FMN-containing dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3679</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000021">
        <property type="protein sequence ID" value="PRC91563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91563">
        <property type="protein sequence ID" value="PRC91563"/>
        <property type="gene ID" value="S2091_3679"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.45.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016164">
        <property type="entry name" value="FAD-linked_Oxase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004113">
        <property type="entry name" value="FAD-linked_oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016171">
        <property type="entry name" value="Vanillyl_alc_oxidase_C-sub2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02913">
        <property type="entry name" value="FAD-oxidase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55103">
        <property type="entry name" value="SSF55103"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="SSF56176"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="1">
        <location>
            <begin position="44"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="472" mass="50856" checksum="3FBDDBF94D6E74FB" modified="2018-07-18" version="1">MTNMTAAHSPLSSDLLIALQHQFTDRCSTSKSVREHHGTDESFYDAMPPDLVVYAQSTAEVASIMQLCHSYNTPVIAYGAGSSLEGHVLAIHGGVCIDLSQMNRVIAVHPEDLTATVQAGVTRKQINLEIKDSGLFFPIDPGADATLGGMSATRASGTNAVRYGTMRENVLALTVVCADGSVIKTGTRAKKSAAGYDLTRLFVGSEGTLGIITEVTVKLYPLPEAISAAVCSFPSTAAAVQSVIQIMQLGVPVARVEFIDTSGVQAINAYSKLALPVQPLLLFEFHGSVNGVREQAELVQEIARDNGSADFEWATHPEDRSRLWTARHNAYFALLQLRPGSRAISTDCCVPISHLAECILETQIDCDKHGLIYTIIGHVGDGNFHVLMLVDPNNPTEIANAEAVNQRMVNRAIAMDGTCTGEHGVGLHKMEFLIQEHGAPAINVMRSIKQTLDPKNLLNPGKIIHWDVVLEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GV34</accession>
    <name>A0A2S9GV34_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="12">L-asparaginase, type II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">S2091_3708</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the asparaginase 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000021">
        <property type="protein sequence ID" value="PRC91592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91592">
        <property type="protein sequence ID" value="PRC91592"/>
        <property type="gene ID" value="S2091_3708"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0110165">
        <property type="term" value="C:cellular anatomical entity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004067">
        <property type="term" value="F:asparaginase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006528">
        <property type="term" value="P:asparagine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08964">
        <property type="entry name" value="L-asparaginase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004550">
        <property type="entry name" value="AsnASE_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036152">
        <property type="entry name" value="Asp/glu_Ase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006034">
        <property type="entry name" value="Asparaginase/glutaminase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020827">
        <property type="entry name" value="Asparaginase/glutaminase_AS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027475">
        <property type="entry name" value="Asparaginase/glutaminase_AS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040919">
        <property type="entry name" value="Asparaginase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027473">
        <property type="entry name" value="L-asparaginase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027474">
        <property type="entry name" value="L-asparaginase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037152">
        <property type="entry name" value="L-asparaginase_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00710">
        <property type="entry name" value="Asparaginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17763">
        <property type="entry name" value="Asparaginase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001220">
        <property type="entry name" value="L-ASNase_gatD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00139">
        <property type="entry name" value="ASNGLNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00870">
        <property type="entry name" value="Asparaginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53774">
        <property type="entry name" value="SSF53774"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00520">
        <property type="entry name" value="asnASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00144">
        <property type="entry name" value="ASN_GLN_ASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00917">
        <property type="entry name" value="ASN_GLN_ASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51732">
        <property type="entry name" value="ASN_GLN_ASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015729304" evidence="9">
        <location>
            <begin position="28"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="domain" description="Asparaginase" evidence="10">
        <location>
            <begin position="36"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="domain" description="Asparaginase_C" evidence="11">
        <location>
            <begin position="249"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="4">
        <location>
            <begin position="125"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="45"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-ester intermediate" evidence="5">
        <location>
            <position position="45"/>
        </location>
    </feature>
    <feature type="active site" description="O-isoaspartyl threonine intermediate" evidence="3">
        <location>
            <position position="45"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="125"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="92"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010518"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR001220-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR001220-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR604550-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF17763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PRC91592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="362" mass="38538" checksum="A6E83A4BF7166EF4" modified="2018-07-18" version="1">MLPNFISRTRLVALFSALLLVSTLAQAEAPPAKLANIVILATGGTIAGSGASSTTTVGYTSATVGVDNLINAVPELKKVANVRGEQVFQIASESLTNEHWLKLAKRVNVLLAQPDVDGIVITHGTDTIEETAYFLDLTVKSRKPVVVVGAMRPSTAISADGPINLYNAVLLAASKDAIGKGVLVSLNDQINAAREVTKTNTSTLDTFKTPELGMLGYIQDNRAHFYRQSTRKNTLDTEFDIGNLDVLPQVDIVYGYANVNRIALDAFVTAGAKGIIYAGVGDGSLAAQIKGPLAEARKKGVIIVRSSRVGQGIVARNGEANDDDLDFVTSDTLNPQKARILLMLGLTKTHDTKALQTMFSIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GV96</accession>
    <name>A0A2S9GV96_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3572</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000020">
        <property type="protein sequence ID" value="PRC91634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91634">
        <property type="protein sequence ID" value="PRC91634"/>
        <property type="gene ID" value="S2091_3572"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015406247" evidence="1">
        <location>
            <begin position="21"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="87" mass="9614" checksum="1EE4F219F9374F29" modified="2018-07-18" version="1">MKKFSQAIALVAVTTLFATAFTTINVDHKTTDMKAIPAQAELNVPQVVIVGKRMSVLEKAQYDVEMLAQNQTQPTKTEQSELHIAIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVB6</accession>
    <name>A0A2S9GVB6_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Glycine cleavage system H protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">gcvH</name>
        <name evidence="6" type="ORF">S2091_3588</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>(R)-lipoate</name>
            <dbReference type="ChEBI" id="CHEBI:83088"/>
        </cofactor>
        <text evidence="3">Binds 1 lipoyl cofactor covalently.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">The glycine cleavage system is composed of four proteins: P, T, L and H.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the GcvH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000020">
        <property type="protein sequence ID" value="PRC91650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91650">
        <property type="protein sequence ID" value="PRC91650"/>
        <property type="gene ID" value="S2091_3588"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005960">
        <property type="term" value="C:glycine cleavage complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019464">
        <property type="term" value="P:glycine decarboxylation via glycine cleavage system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06848">
        <property type="entry name" value="GCS_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00272">
        <property type="entry name" value="GcvH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002930">
        <property type="entry name" value="GCV_H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033753">
        <property type="entry name" value="GCV_H/Fam206"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017453">
        <property type="entry name" value="GCV_H_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11715">
        <property type="entry name" value="PTHR11715"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01597">
        <property type="entry name" value="GCV_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="SSF51230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00527">
        <property type="entry name" value="gcvH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0450">Lipoyl</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="5">
        <location>
            <begin position="20"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-lipoyllysine" evidence="3 4">
        <location>
            <position position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR617453-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC91650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="126" mass="13447" checksum="76CE8294E9F8931D" modified="2018-07-18" version="1">MSNLKFTSEHEWLRLEDNNVVTVGITDYAQGHLGDLVYIQLPDVGADYAAGEEVAVIESVKTAGGIAMPFGGTVVEVNSALNDEPGVVNEDPLGAGWFFKMTTSDVAQMSTLMDEAAYDAYIAKLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWB9</accession>
    <name>A0A2S9GWB9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">LTXXQ motif family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_3361</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CpxP/Spy family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000017">
        <property type="protein sequence ID" value="PRC92019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92019">
        <property type="protein sequence ID" value="PRC92019"/>
        <property type="gene ID" value="S2091_3361"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012899">
        <property type="entry name" value="LTXXQ"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07813">
        <property type="entry name" value="LTXXQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0574">Periplasm</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015441698" evidence="6">
        <location>
            <begin position="27"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="154"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="154"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC92019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="187" mass="21529" checksum="C8D2BD88A6A68558" modified="2018-07-18" version="1">MSNMKQRLVHACAAIGLASFALLAGAQEHQWNSCKDQANKEECRHAQMAKFQAMHEAKLHDSLKITAAQEPAWKTFTESLHQQRDAMMAQRHEMPAHADMEKMSAPERLEKHLAMMQKHQAQMQTLLTSLKAFYAVLTPEQQVTMDKHVARFMKHRHHHHHHHWHHHHGVPQGEHKVDQAPAAATKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWD7</accession>
    <name>A0A2S9GWD7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Transglycosylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_3174</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000016">
        <property type="protein sequence ID" value="PRC92039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92039">
        <property type="protein sequence ID" value="PRC92039"/>
        <property type="gene ID" value="S2091_3174"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3810.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001264">
        <property type="entry name" value="Glyco_trans_51"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023346">
        <property type="entry name" value="Lysozyme-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036950">
        <property type="entry name" value="PBP_transglycosylase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00912">
        <property type="entry name" value="Transgly"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53955">
        <property type="entry name" value="SSF53955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0133">Cell shape</keyword>
    <keyword evidence="6" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="1" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Transgly" evidence="7">
        <location>
            <begin position="130"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC92039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="1089" mass="121790" checksum="5D58E11DC8174305" modified="2018-07-18" version="1">MLRERLRSVLSAKFIKPVAILLLVIISIVAYELHTSRLQAWYLARLGHQLSFHVEPGSSPSIRYPGIGPYDQRLGYTELPSYLDRLKLRDYTVVEQARLSPRMSQMADRGLYAPYAEKDQAGLSVLDFNGAPIYTTSYPERIYSNFNVLPPLVTNSLLYIENHTLLDPSQPLRNPAVEWGRFAHAAWDRTVYFLKPGYESPGGSTLATQIEKYRHSPEGRTASPMEKMRQMYSASVRAYLNGEDTTQVRRQLVVDYVNTVPLSARAGFGEINGIGDGLWAWYGRDFKEINLLLASNSSAPLAARALAYKEVLSLFISQRSPSYYLARIDELEALTDSYLRLMASAEVITPALRDAALAQSLKQQKEHVRPPPAPPERKGVNAVRLNLATLLGVPRLYDLDRLDITVDSALDAQLQQQVTTELRKLRDPAYAKKAGLIDFQLLQHGDPHGVTYSFTLFERTPGGNRVRVQTDNFDQPFDINKGVKLDLGSTAKLRTLITYLEIVADLHRLYVDLQPKALKKVNVAPHDPIKHWALQYLVDATDRSLPTMLEAALDREYSGNPGEQFFTGGGVQSFENFEKYENDRTYTVREGLRYSVNLVYVRLMRDIVHFYMYQVPGSSAHLLGDDDDNDAQRGEYLKRFADREGRVFIAQFYRKYHGMSDPDEEETLAQGIHPTPKRLAVIFRSIAPDASPAQFAKFVNTYSHSADLDADELTKLYDKYSPQRFGLADRGYLAGVHPLELWVAGYLRQHPKATFSQTVEASSTERQEVYKWLFKTRHKNAQDKRIKQLLEVEGFQGIHRAWKRLGYPFDSLVPSYGTAIGASADRPDALAELMGIIMNDGVRLPTVRIDNVHFAVNTPFETVLTRTPAAGEPVLLPEITSLIKPILAEVVQLGTAKRLAGVFALPDGTQIPVGGKTGTGDNRFKIFAKGGGLVSERVVSRSGAFVFYIGDRYFGTVVAYVAGPKAAEYKFTSALTVQILKVLAPTLMHRFNEIAAGPSPNELRYLNTALQQGKQKAELATTPTSVNFKSILATELACPASVTQIGANWPNHKSADNPDVQWEILAGLHIDLCLPTLMQLAQFSPRISP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWI5</accession>
    <name>A0A2S9GWI5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ABC-type branched-chain amino acid transport systems ATPase component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_3217</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000016">
        <property type="protein sequence ID" value="PRC92082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92082">
        <property type="protein sequence ID" value="PRC92082"/>
        <property type="gene ID" value="S2091_3217"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032823">
        <property type="entry name" value="BCA_ABC_TP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12399">
        <property type="entry name" value="BCA_ABC_TP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-1278">Translocase</keyword>
    <feature type="domain" description="ABC transporter" evidence="7">
        <location>
            <begin position="7"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="39"/>
            <end position="46"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC92082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="256" mass="27979" checksum="58F351A826A85592" modified="2018-07-18" version="1">MSEQIMLNIEGVNKSFGGLQALSNVNIQIKKGQIYGLIGPNGAGKTTLFNVITGLYQPDTGKFELAGKRYSPSAPHEVAKVGIARTFQNIRLFGEMTALENVMVGRHVRTHQGVFGAVFQHAAARREEREIKQRAQELLDFVGIGQFAGRTSKFLSYGDQRRLEIARALATDPQLLALDEPAAGMNATEKLALRELLVKIKAEGKTILLIEHDVKLMMGLCDRLTVLDYGKPIAEGLPSEIQKNPAVIEAYLGGGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWT5</accession>
    <name>A0A2S9GWT5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ankyrin repeats (3 copies)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3077</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92161">
        <property type="protein sequence ID" value="PRC92161"/>
        <property type="gene ID" value="S2091_3077"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13857">
        <property type="entry name" value="Ank_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="SSF48403"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015423267" evidence="2">
        <location>
            <begin position="27"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="95"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="125"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="158"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="220" mass="23792" checksum="441F6F2EE86DFCA7" modified="2018-07-18" version="1">MMNKILRRLLVSLLLLITFQPLLALASDQDDFLKAAEFDYVSDLSKFIARGVDPNCHEPMRGETALILAVRENSLRAIDFLVQAPGINLDATANNGNTALMMAAYLGNQHAVETLIAHGAQVNKTGWTPLHYAATAGNDVIVTILLQHDADIDAAAPNGLTSLMMAVRANKTRTVKLLLDNGADPLLSNALSVSALDMAKKLEFRGMVELLETGVKKSNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWX5</accession>
    <name>A0A2S9GWX5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">rRNA methylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_3140</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92224">
        <property type="protein sequence ID" value="PRC92224"/>
        <property type="gene ID" value="S2091_3140"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008173">
        <property type="term" value="F:RNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029064">
        <property type="entry name" value="L30e-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001537">
        <property type="entry name" value="SpoU_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00588">
        <property type="entry name" value="SpoU_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55315">
        <property type="entry name" value="SSF55315"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="SSF75217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SpoU_methylase" evidence="4">
        <location>
            <begin position="113"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC92224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="257" mass="28108" checksum="F9199B11327EDD4D" modified="2018-07-18" version="1">MKLITSRENALYKELKHLATSSQARRKANCTLLDGVHLCQSYLEQIGQPQWCVVSEASQHHPEIAALLVQTEHQLILADALYHALSQVEHGVGIFFVAQTPSLVLPEQITQTAVALDNLQDPGNLGSLLRSAAAAGIRHVFCSTGTVSAWSPKVMRAGMGAHFLLEIHENVDLLSLLKNTTIPVLATSSYATQTVYDCDLKQPLVWLFGHEGQGLSDELMAYATEQVTIPHQGQIESLNVAACAAICFFEQVRQNLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWY4</accession>
    <name>A0A2S9GWY4_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Pseudouridine synthase</fullName>
            <ecNumber evidence="3">5.4.99.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_3149</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Responsible for synthesis of pseudouridine from uracil.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>a uridine in RNA = a pseudouridine in RNA</text>
            <dbReference type="Rhea" id="RHEA:48348"/>
            <dbReference type="Rhea" id="RHEA-COMP:12068"/>
            <dbReference type="Rhea" id="RHEA-COMP:12069"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the pseudouridine synthase RluA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.-" evidence="3"/>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92233">
        <property type="protein sequence ID" value="PRC92233"/>
        <property type="gene ID" value="S2091_3149"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120159">
        <property type="term" value="F:rRNA pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000455">
        <property type="term" value="P:enzyme-directed rRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd02869">
        <property type="entry name" value="PseudoU_synth_RluA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006225">
        <property type="entry name" value="PsdUridine_synth_RluC/D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006224">
        <property type="entry name" value="PsdUridine_synth_RluC/D_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006145">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00849">
        <property type="entry name" value="PseudoU_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01479">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00363">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00005">
        <property type="entry name" value="rluA_subfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01129">
        <property type="entry name" value="PSI_RLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S4" evidence="5">
        <location>
            <begin position="42"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR606225-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU362028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC92233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="336" mass="37998" checksum="598CFBD07E06FEBF" modified="2018-07-18" version="1">MKDLAKFNSKSHEKSASKPEPTTPATVAQVQMLTISEEDVGQRIDNFLLKICKGVPKSHVYQILRSGQVRVNKGRIDQLYRLKLDDVVRVPPVRMAEAKPNNAPRAEFKILFEDAHLLIIDKPSGVAVHGGSGISYGVIEQLRASRPDAKFLELVHRLDRETSGILLLAKKRSALTNLHEQMREGTTDKRYLTLIQGDWKNQRQHIKLPLHKYTAADGERRVRVQADGMESHTIFTLLRHYGAFTLLEAELKTGRTHQIRVHLSASGFAMAGDDKYGDFALNRQLLKAEGMRIALKRMFLHAHQITFTHPETGEKMTVNSPLPQDCEQFLMSLLVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GX49</accession>
    <name>A0A2S9GX49_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2937</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92278">
        <property type="protein sequence ID" value="PRC92278"/>
        <property type="gene ID" value="S2091_2937"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012429">
        <property type="entry name" value="HGSNAT_cat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07786">
        <property type="entry name" value="HGSNAT_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="23"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="63"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="96"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="129"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="156"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="204"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="237"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="286"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="325"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="361"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="domain" description="HGSNAT_cat" evidence="2">
        <location>
            <begin position="17"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="402" mass="45394" checksum="A9160EBF30D90A4A" modified="2018-07-18" version="1">MTNGFLIDDAQDQRGYRLTSIDMLRGLVLLIMALDHVRDFVMMNHQDPMLDPHATPLLFFTRWITHFCAPVFVFLAGTSAGLMTSRKNPNSLGIFLLKRGLWLIFVEVFIISTAFTFSPFGLEQMGGRTFVAMQVIWAIGASMVILAGVQFLGARWCLYIGAIIVLSHNFLDGIWPKNSDGISLPLWAALHTQMGVTAGQFQFFFLYPLLPWVGVMLLGFGTAVLFKQAPEKRNPQLLKIGIGLTLGFVLIRAINLFGDAHGWHYQPENLTATIESFFNTTKYPPSLHYLLMTLGPAAIICAYADQIKGWFKDTLVMFGRVPFTFYVAHFYLAHSIAVIIGMVQGFTFIQMKTFFPFNPKQFGLGLSGVYVVWLLVIVCLYPLCRWVAAVKARRNDWWLSYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GX90</accession>
    <name>A0A2S9GX90_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptidyl-prolyl cis-trans isomerase</fullName>
            <ecNumber evidence="4">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_2996</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the FKBP-type PPIase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="4"/>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92337">
        <property type="protein sequence ID" value="PRC92337"/>
        <property type="gene ID" value="S2091_2996"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001179">
        <property type="entry name" value="PPIase_FKBP_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00254">
        <property type="entry name" value="FKBP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50059">
        <property type="entry name" value="FKBP_PPIASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3 4" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase FKBP-type" evidence="6">
        <location>
            <begin position="6"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="152"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC92337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="183" mass="20401" checksum="9EE10FDF2D1BE15E" modified="2018-07-18" version="1">MKIGRNTVVTVEYTLSDAQGNVIEEGNDPMIYLHGGYENTLPKIEEALEGQQSGYKTEIQLDPDDAFGEYDAELVKVEPRNRLPSPLEVGMQFEGVPDSEDDNEDELIFTVTDIADDKVVLDGNHPLAGIALRFSLHVTEVRAATEDEIKHEHVHDSYGHHEDDDDEDDAGGLGDEYRTHSIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXH6</accession>
    <name>A0A2S9GXH6_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="1">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2799</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="1"/>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92424">
        <property type="protein sequence ID" value="PRC92424"/>
        <property type="gene ID" value="S2091_2799"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019826">
        <property type="entry name" value="Carboxylesterase_B_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00122">
        <property type="entry name" value="CARBOXYLESTERASE_B_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015368626" description="Carboxylic ester hydrolase" evidence="1">
        <location>
            <begin position="21"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="domain" description="COesterase" evidence="2">
        <location>
            <begin position="32"/>
            <end position="520"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU361235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="527" mass="54456" checksum="1C718C4C6228124D" modified="2018-07-18" version="1">MKINLSVVLSLFLASLLLVSCGGKSGSNGSLPSVQTDKGVVVGTTTGTVNKFLGISYAAPPVGNLRWQAPQPATAWSTPFAATAFGAPCVQSVSFFGQASTSEDCLHLNVFAPTGSGPFPVMVWIHGGALITGEASDYDPTALVNSGVIVVTVDYRLGVLGFLTHPALAASNGSAGNYGLMDQQAALKWVQTNISGFGGDPKNVTLFGQSAGGLSTLSQIASPLAAGLFQKAIVESGSYSLQPLTLTAAETAGQSFATNAGCSSQTAACLLALPVSTILANASAIQSNGSQLPTVDLVLLPTTIASALTSGNFNKVPMIEGTNQHEYSVLSDTSIDVTLGGQMTASEYPNYVNGIFGSTIGAELIQYVYPLTSSVTPAWTFDDLMTDFLFSCNGRSIAQVMSTVVPVYTYEFADANAPMFFNVPPRTDGFGAYHAAELAYLFPGSSGTAYYGSPFTAAQTALSTQMIGFWSQFAKTGNPNAAGSSAWPAYTVANDTYLTLAPSAVATSTSFAAAHHCSIWLPSDVGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXL1</accession>
    <name>A0A2S9GXL1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2828</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92453">
        <property type="protein sequence ID" value="PRC92453"/>
        <property type="gene ID" value="S2091_2828"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="88" mass="9843" checksum="84CE4154EDA8D3F6" modified="2018-07-18" version="1">MLDSALITLPWIAMVATLIAAWLVASQSKRKRSLGFWCFILSNALWVLWGWHDGAYALIGLQIGLFFLNLRAVRKNEPVSAKIGVSKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GY27</accession>
    <name>A0A2S9GY27_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2677</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92622">
        <property type="protein sequence ID" value="PRC92622"/>
        <property type="gene ID" value="S2091_2677"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="84" mass="9612" checksum="D007399E08E0BDBF" modified="2018-07-18" version="1">MSKLTNVPTTWHMCLNVRGFLNSAKKREYKMFEHDDGTNMTYDEARNALFDELAQGHEVIPMGKCDNFDYKTGCKGHPNVEVIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GY59</accession>
    <name>A0A2S9GY59_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Methyltransferase domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2708</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92653">
        <property type="protein sequence ID" value="PRC92653"/>
        <property type="gene ID" value="S2091_2708"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="158" mass="18130" checksum="8D786758D2FB8D26" modified="2018-07-18" version="1">MNQKLILDPCCGSRMFWFDKSNPNVLFGDIRNEKHILCDGRELNIAPDVEIDFRNMDFDNNSFKLVVFDPPHLVRAGESGWIGKKYGILQADWKDHLRLGFSECFRVLANDGILIFKWNETQIKVSEILALTPEIPLFGHKSGKNSGTHWICFMKGNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GY94</accession>
    <name>A0A2S9GY94_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2725</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92670">
        <property type="protein sequence ID" value="PRC92670"/>
        <property type="gene ID" value="S2091_2725"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="367" mass="37873" checksum="19863481B08AB5CB" modified="2018-07-18" version="1">MFPTTIPLRTALAGGGRQNATQLGADVNVLSVVATAGDSAILPPATQGVTVRVYNTGLQAAQIFGYQAGNNTDTVETQAAGIRQPANSCIDYYCAIQGNWIPEYQFTHNLLAVTDPVATNDNTQGFGPGSDWFNVLLSREWSCLSAATGAAVWSFDGCVPGVGVDPSGMLTQFGNCAITPALTPFAQFGEEGNLYRNIANPIAGNGTDTTDDILDGFVLPANAFDQAKRGLQLTFQGKFGATANNKRFKIWANPTIVGGSIVAGVNSGGSVSSVGAGALLFDSGVQTNNATGLAVLLQLFKYGVAGSNTQYSQAQPIFGTVHGGVSMPVFSTLVENAPINIVITGSSPTTGAAGDVVLNFSEVNAMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYB6</accession>
    <name>A0A2S9GYB6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2745</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92690">
        <property type="protein sequence ID" value="PRC92690"/>
        <property type="gene ID" value="S2091_2745"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045384">
        <property type="entry name" value="DUF6527"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20137">
        <property type="entry name" value="DUF6527"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="122" mass="13942" checksum="F99F6478F4CD5131" modified="2018-07-18" version="1">MSQLSPILRGGEDGYLMFWCPGCDRAHTVRHGTGLGERWGWNGNALKPTFTPSVLVTYPHWVPPITNENHEQYKENPWEQHQVKDICHSFVVDGRIQFLNDCTHSLAGQTVDLPEWPEETPC</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYE4</accession>
    <name>A0A2S9GYE4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2477</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92747">
        <property type="protein sequence ID" value="PRC92747"/>
        <property type="gene ID" value="S2091_2477"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="315" mass="36119" checksum="869578266170C631" modified="2018-07-18" version="1">MPLNFKWTPGVGVNQDSLKRMLSSVKKPKEPMGESWFMGDEREMHDALINKPLGSMSVFEIERPLEDIASGTSSFGPMAEWENWFEYLLPNLIPVAANLNDTSLHELLITALMTQHPEGISARPYPGYREDVLQTLGQVLMSKSKWKGNEIALERMLIQKPYDMCKGWGWWNASGDLSSTLFLCLKYLETSEIHEWTTSILEIDDPHWRAQILIWLVGSADILKDELKQPFDLHEHVPSIGWNWSWCLKGNFTGIYDGSIPLKPFISNMNSSAFKSVIREILIDDKLGKWIDSISRIEHLKLEALPFIVDVEHLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYH8</accession>
    <name>A0A2S9GYH8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="9">PhnT2: putative 2-aminoethylphosphonate ABC transporter, ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_2504</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92774">
        <property type="protein sequence ID" value="PRC92774"/>
        <property type="gene ID" value="S2091_2504"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017666">
        <property type="entry name" value="AminoethylPonate_ABC_PhnT2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008995">
        <property type="entry name" value="Mo/tungstate-bd_C_term_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50331">
        <property type="entry name" value="SSF50331"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03265">
        <property type="entry name" value="PhnT2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 7 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-1278">Translocase</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="8">
        <location>
            <begin position="29"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="61"/>
            <end position="68"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC92774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="386" mass="42617" checksum="79012BFAA0BC18D3" modified="2018-07-18" version="1">MKFENHNVFKKAQENMNLNEAMADENRWLRIHSINKKFDSFTALNDINLQIKKGEFLCLLGPSGCGKTTLLRIIAGLEAQDSGGVIMSGREIGNLPPAKRNYGIVFQSYALFPNLTVSANVGYALKSNRVEKAKRVSELLDMVDLNGTEHRYPAQLSGGQQQRVALARALATSPSLLLLDEPLSALDAKVREKVRQELRHLQKKLGVTTIMVTHDQDEAMEIADTIAVMSNGRVEQVGTPEQIYREPASRFVAEFVGSANWLSAQLSSDGKISLAGLPQKVMNEKALSSMVNVESTTEVTLFCRPENVQIEAHWQANSQAMMAEVERVEFHSGQRRACLSLCANRAIRILADVGPNDAGYPLLEVGRRVPVTLPAHSVRVFHGAEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYI3</accession>
    <name>A0A2S9GYI3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Phosphonate metabolism transcriptional regulator PhnF</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_2509</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92779">
        <property type="protein sequence ID" value="PRC92779"/>
        <property type="gene ID" value="S2091_2509"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006744">
        <property type="term" value="P:ubiquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07377">
        <property type="entry name" value="WHTH_GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1410.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028978">
        <property type="entry name" value="Chorismate_lyase_/UTRA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012702">
        <property type="entry name" value="CP_lyase_PhnF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011663">
        <property type="entry name" value="UTRA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00392">
        <property type="entry name" value="GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07702">
        <property type="entry name" value="UTRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00035">
        <property type="entry name" value="HTHGNTR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00866">
        <property type="entry name" value="UTRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64288">
        <property type="entry name" value="SSF64288"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02325">
        <property type="entry name" value="C_P_lyase_phnF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50949">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0831">Ubiquinone biosynthesis</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="3">
        <location>
            <begin position="12"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC92779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="250" mass="27736" checksum="311DA5648238EC65" modified="2018-07-18" version="1">MTNKKIDRSAGNSIWRQIEDALSADILSGSLTHRLPNEATLAERFNVNRHTVRQAVKALVERGMVDVVHGSGTFVRDNIIDYQLGRRTRLAHSLAKSDRVGKSQVFNWAVIKGGEGSENVEIAEVLTLLDLPFDASVLAVESLDIVDGNVISVCKQYFPLPRFAGLGEIYTKTGITHLALSQFGVHSFQRRMSRVSARLPDREVAQQLAQPSTFPILYVETVYVDENQQAIEYGISQFNSAAIQIVIEPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYQ2</accession>
    <name>A0A2S9GYQ2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ABC-type multidrug transport system ATPase component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_2571</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92841">
        <property type="protein sequence ID" value="PRC92841"/>
        <property type="gene ID" value="S2091_2571"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-1278">Translocase</keyword>
    <feature type="domain" description="ABC transporter" evidence="7">
        <location>
            <begin position="6"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="38"/>
            <end position="45"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC92841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="285" mass="32054" checksum="46A2A0A04346131E" modified="2018-07-18" version="1">MNHPIIQLSNIVKSFDQHSVLRGLNWEVAPGSVIGLLGRNGAGKSTLLESALGLRDIDSGSNLLFGESVKHLSETTKEKIGYVPQQSDLFEWFTPRQMLAYFKSFYPRWNQEKVDGLMSRWAIPQDRLISKLSGGEKQRLSIIRALAHDPDLLILDEPVASLDPAGRRDFLRELINDVIQRETTVVFSTHILSDLERIAMTVAFLNDGVIKLQEPLDNLLENTVRIVTDNSKIASFSKILSRTEIDANQSSLLVQLTPQELLWSQKNFVNMEAIGLEDLFIDLTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYY8</accession>
    <name>A0A2S9GYY8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acetyltransferase (GNAT) domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2344</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92927">
        <property type="protein sequence ID" value="PRC92927"/>
        <property type="gene ID" value="S2091_2344"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="11"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="197" mass="22512" checksum="36D2519669E67A07" modified="2018-07-18" version="1">MQAITLTGRYVTLEPLAQEHLTGLQAAAADGQLWNLFFTGVPTKETTQQWLDTALALQADKKALPFVVRENSSGEIVGTTRYCNIEMNHKRLEIGFTWYAKRVQRGAVNTECKLLLLRHAFEQLECNVVEFRTDWFNQTSQRAIERLGAKRDGVLRNHVIAPNGRVKDTVVYSILNNEWNGIQEHLRFKLERHSASC</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYZ4</accession>
    <name>A0A2S9GYZ4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ATPase family associated with various cellular activities (AAA)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2345</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92928">
        <property type="protein sequence ID" value="PRC92928"/>
        <property type="gene ID" value="S2091_2345"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="1">
        <location>
            <begin position="30"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="285" mass="32786" checksum="7D237072FC9B5E19" modified="2018-07-18" version="1">MQTPQTRFEGSESYVATDDLKLAVNAALTLQRPLLIKGEPGTGKTMLAEEVAAALNMPLMQWHIKSTTKAQQGLYEYDAVSRLRDSQLGDERVKDIHNYIVKGVLWQAFTADQPVVLLIDEIDKADIEFPNDLLRELDRMEFYVYETREMVRAVHRPLVIITSNNEKELPDAFLRRCFFHYIKFPDAETMQEIVRVHFPTLKNDLLAQALTSFYEVREVAGIKKKPSTSELLDWLKLLLAEDIPAEALRSKDNKAIVPPLHGALLKNEQDVHLFERIVMMTRHNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZH9</accession>
    <name>A0A2S9GZH9_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7 8">Transcription elongation factor GreA</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Transcript cleavage factor GreA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">greA</name>
        <name evidence="11" type="ORF">S2091_2228</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 7 8">Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7 8">Belongs to the GreA/GreB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93142">
        <property type="protein sequence ID" value="PRC93142"/>
        <property type="gene ID" value="S2091_2228"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070063">
        <property type="term" value="F:RNA polymerase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032784">
        <property type="term" value="P:regulation of DNA-templated transcription, elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00105">
        <property type="entry name" value="GreA_GreB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036953">
        <property type="entry name" value="GreA/GreB_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018151">
        <property type="entry name" value="TF_GreA/GreB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006359">
        <property type="entry name" value="Tscrpt_elong_fac_GreA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028624">
        <property type="entry name" value="Tscrpt_elong_fac_GreA/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001437">
        <property type="entry name" value="Tscrpt_elong_fac_GreA/B_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023459">
        <property type="entry name" value="Tscrpt_elong_fac_GreA/B_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022691">
        <property type="entry name" value="Tscrpt_elong_fac_GreA/B_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036805">
        <property type="entry name" value="Tscrpt_elong_fac_GreA/B_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30437">
        <property type="entry name" value="PTHR30437"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01272">
        <property type="entry name" value="GreA_GreB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03449">
        <property type="entry name" value="GreA_GreB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006092">
        <property type="entry name" value="GreA_GreB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46557">
        <property type="entry name" value="SSF46557"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01462">
        <property type="entry name" value="greA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00829">
        <property type="entry name" value="GREAB_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00830">
        <property type="entry name" value="GREAB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="11" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="11" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7 8" id="KW-0804">Transcription</keyword>
    <keyword evidence="3 7 8" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="GreA_GreB_N" evidence="10">
        <location>
            <begin position="4"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="domain" description="GreA_GreB" evidence="9">
        <location>
            <begin position="83"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF03449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC93142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="158" mass="17269" checksum="9F7E5388FEE7E8B6" modified="2018-07-18" version="1">MSTVPLTKFGAELLKQELHQLKTRERHAVISAIAEARSHGDLSENAEYDAAKERQSFVEGRIADLEGKLSSAQIIDPATLDAEGRIVFASTVDLDDLETGEKVTYQIVGEDEADLKEKKVSITSPIARALIGKYAGDIIAVQAPAGVREYEVIDVRYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZR2</accession>
    <name>A0A2S9GZR2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">RibD C-terminal domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2274</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93188">
        <property type="protein sequence ID" value="PRC93188"/>
        <property type="gene ID" value="S2091_2274"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008703">
        <property type="term" value="F:5-amino-6-(5-phosphoribosylamino)uracil reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.430.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024072">
        <property type="entry name" value="DHFR-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002734">
        <property type="entry name" value="RibDG_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01872">
        <property type="entry name" value="RibD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53597">
        <property type="entry name" value="SSF53597"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RibD_C" evidence="1">
        <location>
            <begin position="9"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="215" mass="23430" checksum="BFBB2EEF4AA0F7FC" modified="2018-07-18" version="1">MSKLRVECFSMSVDGFCAGPNQSLENPLGVGGMGLHEWAFPTRTFQKMHGNGDGTTGIDDDYCARGFSNIGAWILGRNMFGPVRGPWPDMSWKGWWGDNPPYHTPVFVLTQHPRESITMEGGTVFHFVTDGILIALERAKEAAMGMDVRVGGGVATVQQYLRAGLVDEMHIAIAPILLGSGESLFSNIDMPSLGYQCSEHVSSPNAMHVILKKKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZV6</accession>
    <name>A0A2S9GZV6_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">Cell shape-determining protein MreC</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4 5">Cell shape protein MreC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_2007</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Involved in formation and maintenance of cell shape.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the MreC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93269">
        <property type="protein sequence ID" value="PRC93269"/>
        <property type="gene ID" value="S2091_2007"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.340">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042177">
        <property type="entry name" value="Cell/Rod_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042175">
        <property type="entry name" value="Cell/Rod_MreC_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007221">
        <property type="entry name" value="MreC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34138">
        <property type="entry name" value="PTHR34138"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04085">
        <property type="entry name" value="MreC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038471">
        <property type="entry name" value="MreC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00219">
        <property type="entry name" value="mreC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0133">Cell shape</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="283"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00032089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR038471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC93269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="328" mass="36303" checksum="F6B348DF99C7BD3E" modified="2018-07-18" version="1">MEYRPPPLFKQGASARVKVVFFSLVALMLLVIDARLQTLELVRQVVGSALYPLQMLAVMPRDLAYNMGDYFTQLTALEKENAALKRSQLEQALNVQHGQQLQFENAQLRRLLATSEHVPVKSVMGEILYDARDSFSRRIIVNRGIKHGVALGQPVIDDQGVVGQITRVFPFTSEVTLLTDKDQAIPVQVQRNGLRSVIYGKGQVGNLELRVPSNADIKAGDILVTSGIDGIYPPGLFVARATVVENSASTTFERIVCLPMAGLDRHKEVLILLVATHIEARPEDEDNKAKKVNRRVTRDSAESTTKVKEPVKEDAKDAVKEAEKVSQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H005</accession>
    <name>A0A2S9H005_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lysophospholipase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2052</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93314">
        <property type="protein sequence ID" value="PRC93314"/>
        <property type="gene ID" value="S2091_2052"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022742">
        <property type="entry name" value="Hydrolase_4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12146">
        <property type="entry name" value="Hydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hydrolase_4" evidence="1">
        <location>
            <begin position="27"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="278" mass="30228" checksum="47A3BF0BEC1BB9D6" modified="2018-07-18" version="1">MVGAHESRLSMADGTELFIRDWLIEGETQSCIVILHGLGEHCGRYNHVAAFLNSCGFSVRTYDHRGHGQSTGARGDIPDLLAIVHDAEIIINEFAQHCQTRPILLGHSMGGLFAARVATAANIPLSGLILSSPALALRLSKIEKILLSVMSSIAPHFAISNGLKPALLSHDPAVMTAYENDPLVHKKITASLLNGMFAAIEFAQTRAPILDIPTLLLVAEADQLVDPQGSHDFFESLPSNLGTAHFYTDFYHEIFNEVGAADVFHDLQTWLAARHFST</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H097</accession>
    <name>A0A2S9H097_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HTH-type transcriptional regulator</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1765</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GbsR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93378">
        <property type="protein sequence ID" value="PRC93378"/>
        <property type="gene ID" value="S2091_1765"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026282">
        <property type="entry name" value="MJ1563"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12802">
        <property type="entry name" value="MarR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006707">
        <property type="entry name" value="MJ1563"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH marR-type" evidence="2">
        <location>
            <begin position="29"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR006707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="192" mass="22378" checksum="90D9C86BE9EE6ECC" modified="2018-07-18" version="1">MSITPLTPLSLRFISHFGEMGSRWGINRTVGQIYALLYVQGKALNADEIAEHLTFSRSNVSMGLKELQSWRLVKLLHKPGDRREYFEPPQDIWDIFKALLEERRRREIEPTLSMLRDALLEQPTNEADQVAQQRMREMYDLIELSSSWFDDVQRLSPETLTSLMKMGSKVKKLLDVREKFRFSGTSNDTVIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0J6</accession>
    <name>A0A2S9H0J6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_1857</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93470">
        <property type="protein sequence ID" value="PRC93470"/>
        <property type="gene ID" value="S2091_1857"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015562">
        <property type="term" value="F:efflux transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003423">
        <property type="entry name" value="OMP_efflux"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010131">
        <property type="entry name" value="RND_efflux_OM_lipoprot_NodT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02321">
        <property type="entry name" value="OEP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01845">
        <property type="entry name" value="outer_NodT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2 4" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0564">Palmitate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1134">Transmembrane beta strand</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015375188" evidence="2">
        <location>
            <begin position="35"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="406"/>
            <end position="433"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU362097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC93470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="503" mass="53767" checksum="6F1E497B42A8C8E3" modified="2018-07-18" version="1">MMCQPDHYPFKVKLLCSIRLWSVGMIATMLSACAVGPDFVPPASPTESRYTSEPQAEQTVVADTQAQHFSAATQIPADWWRLFKSEQLDAVVQLAIAHNPTLEASEATLRQSQDNLRAGYGVFYPQIDAGLNAARERSAPTQQGLQTPGSIFNFVSIGGSISYVLDVFGGQRRAVEGLSAQRDYQLFAHKAAYVTLSANVVNACIARAAYSAQIRATEELIALEGEQLAATEAQVNAGTGAYTSVLSMRSLIAANQGSLAPLKQKLSQAEHLLIALEGVSFSTANLPDIDLKGLSLPLALPVSLPSDLVRQRPDILQAEAQLHAASANIGVATAAMFPSFSLDGTFGVAGSSFGNLSAENGKFWSVGPSISIPLFRGGSLWFGRKAALDAYDQSRAGYRQTVLGAFEQVADSLKALEHDAESLQAQVESRNAAEEAFHLLQIGYKSGLSAYLDVLTADVQFHQANIAYLQAVAQRQQDTVALFVALGGGWWNTQVAAKEGKTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0L9</accession>
    <name>A0A2S9H0L9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1895</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93508">
        <property type="protein sequence ID" value="PRC93508"/>
        <property type="gene ID" value="S2091_1895"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015478669" evidence="1">
        <location>
            <begin position="24"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="146" mass="16223" checksum="7CFAD886605FE633" modified="2018-07-18" version="1">MKKLVLLALASAATFVLPAVVMAQEVKPPEVNISGVHLNHEENQIVQYMSDDEFYKFKQTYELSNGNTLSLFSRFNNKYAKLGDGTWHRIVATGPNSFVSKDHQLKMEINLQNDDKVSGYLLMPAASPAVAGNDVTSVAYVKVVFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0R3</accession>
    <name>A0A2S9H0R3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NUDIX domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1573</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93572">
        <property type="protein sequence ID" value="PRC93572"/>
        <property type="gene ID" value="S2091_1573"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008828">
        <property type="term" value="F:dATP pyrophosphohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019177">
        <property type="term" value="F:dihydroneopterin triphosphate pyrophosphohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046656">
        <property type="term" value="P:folic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003564">
        <property type="entry name" value="DHNTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01404">
        <property type="entry name" value="NPPPHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="1">
        <location>
            <begin position="5"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="149" mass="17215" checksum="36E0A77637E982C9" modified="2018-07-18" version="1">MNKQYKIPESVLVIIHTVDLQVLIMERADQEKFWQSVTGSKDDLNETYAATAAREVQEETGLDAAQFKLTDWQLQNVYEIYPIWRHRYAPGVTQNTEHVFALTLPQIVPITLAPGEHRQYRWLPYKEAADCCFSSSNAEAILQLPHRIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0U5</accession>
    <name>A0A2S9H0U5_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Putative mRNA interferase YoeB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_1873</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the YoeB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93486">
        <property type="protein sequence ID" value="PRC93486"/>
        <property type="gene ID" value="S2091_1873"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006401">
        <property type="term" value="P:RNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2310.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035093">
        <property type="entry name" value="RelE/ParE_toxin_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009614">
        <property type="entry name" value="YoeB_toxin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06769">
        <property type="entry name" value="YoeB_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143011">
        <property type="entry name" value="SSF143011"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02116">
        <property type="entry name" value="toxin_Txe_YoeB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00030388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC93486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="88" mass="10436" checksum="BCA78A1025D1CE99" modified="2018-07-18" version="1">MVIWNLAYSKYALKDAKKLSGAGLKDKAQALLNILEIDPFQNPPPYEKLVGDLKDAYSRRINIQHRLVYEVFREERTVRILRMWSHYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0W9</accession>
    <name>A0A2S9H0W9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="11">TonB family C-terminal domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">S2091_1622</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
            <orientation evidence="1">Periplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TonB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93621">
        <property type="protein sequence ID" value="PRC93621"/>
        <property type="gene ID" value="S2091_1622"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006260">
        <property type="entry name" value="TonB/TolA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037682">
        <property type="entry name" value="TonB_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03544">
        <property type="entry name" value="TonB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01352">
        <property type="entry name" value="tonB_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="TonB_C" evidence="10">
        <location>
            <begin position="143"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="60"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="60"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF03544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC93621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="223" mass="23821" checksum="BE12BB2F91BF590C" modified="2018-07-18" version="1">MPILKTLFAKLHRATPLIIIIAVHVSIFALLQNSFSPNTVAPGLAVKEVTVNFITPDPVSEAPPVPKASTPPKTVPIATPAKPTILPTPVETALAAPAPTHEAVNTTTESVIAHPQPAETTPVASTAPAVPKTITGVSYLQEPQVVYPMISKRMNEQGRVLLHILVDEFGVPQKIKIQQSSGSERLDEAAKVAAAKALFKPYREDGKSQPVYVVVPINFRLNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H107</accession>
    <name>A0A2S9H107_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 6">Bacterioferritin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_1631</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Iron-storage protein.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Oligomer of 24 subunits, arranged as 12 dimers, that are packed together to form an approximately spherical molecule with a central cavity, in which large amounts of iron can be deposited.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4 6">Belongs to the bacterioferritin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93630">
        <property type="protein sequence ID" value="PRC93630"/>
        <property type="gene ID" value="S2091_1631"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008199">
        <property type="term" value="F:ferric iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006879">
        <property type="term" value="P:cellular iron ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006826">
        <property type="term" value="P:iron ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00907">
        <property type="entry name" value="Bacterioferritin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002024">
        <property type="entry name" value="Bacterioferritin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012347">
        <property type="entry name" value="Ferritin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009040">
        <property type="entry name" value="Ferritin-like_diiron"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008331">
        <property type="entry name" value="Ferritin_DPS_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00210">
        <property type="entry name" value="Ferritin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002560">
        <property type="entry name" value="Bacterioferritin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00601">
        <property type="entry name" value="BACFERRITIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="SSF47240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00754">
        <property type="entry name" value="bfr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00549">
        <property type="entry name" value="BACTERIOFERRITIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50905">
        <property type="entry name" value="FERRITIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 6" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="4 6" id="KW-0409">Iron storage</keyword>
    <keyword evidence="4 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ferritin-like diiron" evidence="7">
        <location>
            <begin position="1"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="18"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="51"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="52"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="54"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="94"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="128"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="130"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011713"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR002560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR002560-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC93630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="158" mass="17953" checksum="EA63B6E986463AC4" modified="2018-07-18" version="1">MKGDAKVVKLLNAQLTNELSAINQYYLHSRMYKNWGFDKIAKKEFEESIGEMKHADKLIDRILMLDGLPNLQALHKLMIGEHTAEMLECDLKLETAAQKTVKEGISVCEAHGDYVSRELFQEILEDTEEHIDWLGTQIDLIAKVGIQNYLQSQMSAGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H160</accession>
    <name>A0A2S9H160_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1723</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93722">
        <property type="protein sequence ID" value="PRC93722"/>
        <property type="gene ID" value="S2091_1723"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.620.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012348">
        <property type="entry name" value="RNR-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="SSF47240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="282" mass="33194" checksum="057F5DFB4BE7FBF6" modified="2018-07-18" version="1">MLYPELFKSLEQVRWNMETDIPWDQFDASKLTLEQAQTIKMNAITEWSALPATEMFLRDNRNDSDFCAFMSVWFFEEQKHSLVLMEYLRRFYPELVPTEEELDKVRFEFDPAPPLETLMLHFCGEIRLNHWYRCASDWHTEPVIKQIYKMISQDEARHGGAYLRYMKKALNEVGDAASSAFAKIGVLMASSRRTEKPLHPTNLHVNQALFPHDTIQSRLPDPAWLERWLDGQIKFDGVWEKKVVERILHNLSLLFEQSFATVQDLNRYRKEISSRMAAAALE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1B1</accession>
    <name>A0A2S9H1B1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Dynamin family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1378</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93769">
        <property type="protein sequence ID" value="PRC93769"/>
        <property type="gene ID" value="S2091_1378"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045063">
        <property type="entry name" value="Dynamin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00350">
        <property type="entry name" value="Dynamin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dynamin_N" evidence="1">
        <location>
            <begin position="57"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="645" mass="72774" checksum="D311AFED9F9A8D1E" modified="2018-07-18" version="1">MSNLVKKFQQYSEWRSGVISSLHRYRAWTHAADTSDAVTEQRITHLLEKLTDDKLTIAFVAEFSRGKSELINAIFFADYGQRILPSAAGRTTMCPTELLYDETFPPSIRLLPIETRAESQTTSEFKTQNQVWTVLPLDIQSADGMLEAFKQVSMTKHVSVAEAKSYGLYDEDDPDSALELNELGLVEISQWRHAIINFPHPLLKDGLIIVDTPGLNAIGTEPELTLNLIPNAHAVLFILAADTGVTKSDIDVWRNHIGAGPGRMVILNKIDSMWDELRSEAEVEEQIKHQITSAAHLLSLQENQIFPVSAQKGLVAKIHGDAPLLVKSRLLKLEHALSNELIPSKQEIIRSQLNKDIHSLLQVQHTLMGARHRGVFEQMSELKSLRGKNKKVIEHMMRRVEIEKQEFDQSLMKLQGTRAVFTRLSTEVFTSLGMDILKEEVRHTRDAMENCKLSSGLVAAVHEFFSRTKRNLAMSNQKTNEIFEMMSIMYKKFSTEHGLALATPMPFSLDKYRAELEAVESIFQQQFGVVTLLTNSRVALMQKFFDSIANRVKQCFLSANRDVEAWQKAIMAPLEAQIHEHKSQLKNRMQSIQRIHMATDSLEDKIMSFEVMQSDLEGLKNGLAELEAEIMTALSGTLGKIPVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1B6</accession>
    <name>A0A2S9H1B6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_1657</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93656">
        <property type="protein sequence ID" value="PRC93656"/>
        <property type="gene ID" value="S2091_1657"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="3">
        <location>
            <begin position="12"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="4">
        <location>
            <begin position="135"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="2">
        <location>
            <begin position="135"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC93656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="234" mass="26098" checksum="A12C8EBE628DADF9" modified="2018-07-18" version="1">MATSVANPLALRVLTIEDDPITAEEIAAELSAHGFSVEIVSDGTIGLDKACKGNYNAITLDRMLPGLDGLSIVTRLRAAGINTPVLMISALSDVDERVRGLRAGGDDYLTKPFATDEMSARLEVLLRRRQTPALVVTLQVADLSMNLMERSVRRGELTLELKTTEFRLLEYMMRNSDQVLTRSMIFEAVWNYHFDPYTNLIEVHMARLRKKINLPELTPLIHTVRGSGYLLGVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1N6</accession>
    <name>A0A2S9H1N6_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Lipoprotein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">S2091_1487</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell outer membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the YscJ lipoprotein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93878">
        <property type="protein sequence ID" value="PRC93878"/>
        <property type="gene ID" value="S2091_1487"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006182">
        <property type="entry name" value="FliF_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003282">
        <property type="entry name" value="T3SS_HrcJ/YscJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043427">
        <property type="entry name" value="YscJ/FliF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30046">
        <property type="entry name" value="PTHR30046"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01514">
        <property type="entry name" value="YscJ_FliF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01338">
        <property type="entry name" value="TYPE3OMKPROT"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02544">
        <property type="entry name" value="III_secr_YscJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="8 9 11" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 9" id="KW-0564">Palmitate</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0732">Signal</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="206"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="domain" description="YscJ_FliF" evidence="10">
        <location>
            <begin position="18"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009509"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU364102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC93878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="246" mass="26896" checksum="93E5BF5DC8F436D7" modified="2018-07-18" version="1">MNKLAIMGLLCLTLVGCKQESLLKGLDQGQANEVVAVLHRNNIESGKRDNGKTGYSVDVDKVDFAAAVDILKSYDLPSRKAVQIADMFPVDSLVASPRAEKARLYSGIEQRLEQSLYTIAGVVSARVHVSYDLDAGEGGRTVRPVHLSALASYEGDVDVPALINDIKRFLKNSFTEVGYDNISVVLSRRTALQHETPRKLEKSDGGMLAGVLAVLVAAIAALMWLWHKYGDKGKARLKIMRDEKTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1V6</accession>
    <name>A0A2S9H1V6_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Thiol:disulfide interchange protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">S2091_1121</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the thioredoxin family. DsbC subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC93948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93948">
        <property type="protein sequence ID" value="PRC93948"/>
        <property type="gene ID" value="S2091_1121"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd03020">
        <property type="entry name" value="DsbA_DsbC_DsbG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033954">
        <property type="entry name" value="DiS-bond_Isoase_DsbC/G"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018950">
        <property type="entry name" value="DiS-bond_isomerase_DsbC/G_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009094">
        <property type="entry name" value="DiS-bond_isomerase_DsbC/G_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012336">
        <property type="entry name" value="Thioredoxin-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10411">
        <property type="entry name" value="DsbC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13098">
        <property type="entry name" value="Thioredoxin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54423">
        <property type="entry name" value="SSF54423"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4 7" id="KW-0574">Periplasm</keyword>
    <keyword evidence="6 7" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015372987" description="Thiol:disulfide interchange protein" evidence="7">
        <location>
            <begin position="26"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="domain" description="DsbC_N" evidence="8">
        <location>
            <begin position="35"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin-like_fold" evidence="9">
        <location>
            <begin position="117"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU364038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF10411"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF13098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC93948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="244" mass="26723" checksum="928C5433B5724C2C" modified="2018-07-18" version="1">MQSIKKIGLVVSSLLMSLILTTACAQTDHEAAIKKLLEPKLGNEVVVDAVKKTSYAGLYEVQVGGDIFYTDEKAQFLFVGNVMDLKTHKNVTRARLESLNNVKIADLPLELAMKQVKGDGTRVIAVFEDPNCGYCKRLRKEMQKIDNITVYTFMYDILSEDSAIKSNNIWCSANPAQAWNDWMLNGNAAPDAPASCTTSPHEKILALGAKLHITGTPAIFFADGTRAPGFIDANALEKKLADVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1Y2</accession>
    <name>A0A2S9H1Y2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1168</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC93995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93995">
        <property type="protein sequence ID" value="PRC93995"/>
        <property type="gene ID" value="S2091_1168"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012808">
        <property type="entry name" value="CHP02453"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015996">
        <property type="entry name" value="UCP028451"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36452">
        <property type="entry name" value="PTHR36452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09365">
        <property type="entry name" value="DUF2461"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028451">
        <property type="entry name" value="UCP028451"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02453">
        <property type="entry name" value="TIGR02453"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="228" mass="25755" checksum="55D3AC7211FBE1B5" modified="2018-07-18" version="1">MHIQDLTRYLAELSDNNNRAWFVMNKPRYDILREEFLALVSDLIVQISKFDPLILGCNPKKALFRINRDVRFANDKSPYKTTFSAAIAAGDIKKPSQGGGPVYYFHLSANGDLRYAVGEYTPPADRLKQIRNHIAENGASLAKILKAKKLQAAFGGLQEKDKLLRAPKGFEPDHPQIELIKLKHFMVWNVLALSELTIGQQTEELTKILVGAYKDAYPLVCWLREAGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1Z7</accession>
    <name>A0A2S9H1Z7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1146</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC93973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93973">
        <property type="protein sequence ID" value="PRC93973"/>
        <property type="gene ID" value="S2091_1146"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="201" mass="22886" checksum="B27EF5CE83DBF4E9" modified="2018-07-18" version="1">MKLISHRRNSIDELRATNHKYGVEVDIRSEGQKLIMHHDPFVAGESFDEWIDVYQHGTLILNVKEEGLESRLIAIMTSKGIDDYFFLDQSFPFLVKWSKAGEHRCAVRVSEFESIETALTLAGKVDWVWVDCFSQFPLSGDDAQRLMNAGFKLCLVSPELQGRDAETEIPALASLLRERNIKSDAVCTKRPDLWEKVVASQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2C9</accession>
    <name>A0A2S9H2C9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Mce related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1189</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94016">
        <property type="protein sequence ID" value="PRC94016"/>
        <property type="gene ID" value="S2091_1189"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015914">
        <property type="term" value="P:phospholipid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030970">
        <property type="entry name" value="ABC_MlaD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003399">
        <property type="entry name" value="Mce/MlaD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02470">
        <property type="entry name" value="MlaD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04430">
        <property type="entry name" value="OM_asym_MlaD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="domain" description="MlaD" evidence="2">
        <location>
            <begin position="40"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="157" mass="16852" checksum="C898A06800325C3A" modified="2018-07-18" version="1">MQNKSLDFWVGLFVLMGAVALLFLALRVGNMSSFSLNSSYIVITKFDNIGGLKPRAPVKSAGVVVGRVGAISFDDSTFQAVVSLQLDQRYKFPKDSSAKILTSGLLGEQYIGLEPGGDVNALVAGDKIKMTQSAIVLENLISQFLFSKAAEGKDENK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2K1</accession>
    <name>A0A2S9H2K1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0833</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94212">
        <property type="protein sequence ID" value="PRC94212"/>
        <property type="gene ID" value="S2091_0833"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="75" mass="8763" checksum="472934606499F74E" modified="2018-07-18" version="1">MYRNRSDSRKLSPELLKQHGVLHAEENPVQQLAPGTLRVTKTYLNFVVAPFHECHHLLRIFIDMLMQAFDDAQFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2M3</accession>
    <name>A0A2S9H2M3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0828</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94207">
        <property type="protein sequence ID" value="PRC94207"/>
        <property type="gene ID" value="S2091_0828"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="134" mass="14991" checksum="C0E41D55D2A461E5" modified="2018-07-18" version="1">MIHSESSTLKSSVGPKLPTVCIANAIDTLRLTIFRAPTEGDRERIHNSNYPQQDQAVFWRPLDKLIVSESPIVGFDWVTQMLGIKKAKNIWPENSCGSLFKDVVTSKNLQMEISEWCADSGGFELIVHTTTPET</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2M7</accession>
    <name>A0A2S9H2M7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">GGDEF: diguanylate cyclase (GGDEF) domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_0839</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94218">
        <property type="protein sequence ID" value="PRC94218"/>
        <property type="gene ID" value="S2091_0839"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01948">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001633">
        <property type="entry name" value="EAL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035919">
        <property type="entry name" value="EAL_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015869">
        <property type="entry name" value="Transcrpt_antiterm_NusG_bac_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00563">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13492">
        <property type="entry name" value="GAF_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00052">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141868">
        <property type="entry name" value="SSF141868"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50883">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01014">
        <property type="entry name" value="NUSG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PAS" evidence="1">
        <location>
            <begin position="690"/>
            <end position="760"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="2">
        <location>
            <begin position="763"/>
            <end position="815"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="4">
        <location>
            <begin position="847"/>
            <end position="985"/>
        </location>
    </feature>
    <feature type="domain" description="EAL" evidence="3">
        <location>
            <begin position="994"/>
            <end position="1248"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC94218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="1250" mass="139483" checksum="C734704AFD615EBB" modified="2018-07-18" version="1">MTDHFLDLFALDEAVTALDVHLSRVDGTQRIFAVVAMAWQLRQRDYNRSLLLASEAETLLQTADMDETEKTRCKARVRLIRAEFKTLGADLDGGEHEINLALALFEAINDKLGEGDCQWLLAYIWQDRGRSQHIDIHLSLALQHYQLANDLIRVAATQARSMARAAFSDAAATAIQLTELFPDPVHLHDSILTWILTARATVAALTDDPGAAIKLDLQAYQAALNSGQIRHALICAANVAEDFSTLSDLDSALEWAENALSLARTTNWPYNNGLGLMQVGDVLRRLERFDEAEAFLLEAISRLETMPRSRGHINALNHLGMLALDMGDFEKSLSWFLKIEQNIEAQRDRDQLIIMTRGQATALLRLGRKDEAAVKAAEALELANAQGSADEQIKSLRVLAELHSNSNGVKSKNMAQPSAALHYLDQAVKIAKTISGYKVSSDLLNQIANEYATNGDFRSAYEAGLAATAARNNSRLSEAQNRAIAIQVRREMDRTRAETEQHIKLAAALQNTNSTLETLGLIGRKITASLNSQEVLEALHHHADDLLDTWSFIIYLFNEDKSKLQVAFAVETGLTKPFPFYEVSVDNPTSLSARCAREQHEIVINSALDQSSHSIIPGTQKATSLLFAPLMVGQRMLGVMSIQSPNEHAYGERECSIFRTLCAYGAIALDNAAAYSAVDAARERSLIHEQELRIAAIAFESHEGMFITDAKQKILRINSAFSNITGYSSEEMLLQSPSMFKSPQHDDDFYRMVMQTVKDTETWQGEVWTQRKNGEDFPLWLTVTAVRTFENVITNYIFSLVDITDRKLAEDEIRSLAFYDSLTKLPNRRLLTERLKHALATSSRTKKEGALLFIDLDNFKKLNDTRGHDVGDLLLELVGQRLSLCLREGDTAARLGGDEFVVLLEELNEDASHAADLAELVALKIQSELNQPYLLKGKTHHISPSIGVTLFQSHDVNVDDLLKHADLAMYQAKDAGRNTIRFFDPEMQKAVDRHAALEADLRQALESQQFVLHYQIQMDSNDQIIGAEALIRWNHPERGMVSPSEFISVAEENGLILPLGDWILDTACKQLHIWSLHPDTAHLSLAVNISARQFHDAHFVNNVMTALRSNNADPYKLKIELTESLLLKDIDAVISKMRELMLNGVRFSLDDFGTGYSSLAYLKRLPLEQLKIDQTFVRDIFIDSNDLAIVRAIVTLGLSMGLGIIAEGVETAEQREFLQSCGCSMFQGYLFGRPTPVELLNFNKKVLVHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2P1</accession>
    <name>A0A2S9H2P1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative endonuclease containing a URI domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0859</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94238">
        <property type="protein sequence ID" value="PRC94238"/>
        <property type="gene ID" value="S2091_0859"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000305">
        <property type="entry name" value="GIY-YIG_endonuc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035901">
        <property type="entry name" value="GIY-YIG_endonuc_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01541">
        <property type="entry name" value="GIY-YIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82771">
        <property type="entry name" value="SSF82771"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50164">
        <property type="entry name" value="GIY_YIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GIY-YIG" evidence="1">
        <location>
            <begin position="2"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="102" mass="12048" checksum="40679A11D6E06486" modified="2018-07-18" version="1">MKAPAIYLLANQRNGTLYIGVTSDLIQGAWQHREGIAQGFTHQHQVKTLVWHEQHETMESAITREKALKKWNRKWKLRLIEKFNPEWKDLWLEITGQESSSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2Q2</accession>
    <name>A0A2S9H2Q2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0869</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94248">
        <property type="protein sequence ID" value="PRC94248"/>
        <property type="gene ID" value="S2091_0869"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015394225" evidence="1">
        <location>
            <begin position="27"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="262" mass="29029" checksum="5B762BAA09322DD4" modified="2018-07-18" version="1">MKHNSIFKIIAALSVNCLLSVSVTHAQSVLHIASDDWCPYICAQNGHLTSGYLVDVATQAMLISGYQVESALIPLTRAMHEASTGSIQGVYAPPIDDRLRLSIPIAYSRACFYTLAEQTWRYQGIASLHNVVVGIVGEYGYDDNLMDAYVIKNQHKHLLIDTSFGENAGLSNLKKLLAARFPVMLEHEAVMTMLAKNLGAEYKIRQAGCLEHALPLPIGFTKMDSHNEDWIRALTLGIQQLEASGKLAELRQHYHIPEINTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2R5</accession>
    <name>A0A2S9H2R5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0892</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94271">
        <property type="protein sequence ID" value="PRC94271"/>
        <property type="gene ID" value="S2091_0892"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="68"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="97"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="121"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="151" mass="16531" checksum="94DCEF9716A4AE3A" modified="2018-07-18" version="1">MKELKLTEENSWKAALYFSRIALAAAFLSAVADRFGLWGKMGELGVSWGSMAGFYPHVAKLSPWSPAAFIPALAWLITILEALLGIFLLLGIQVRKTALFSALLLLLFAMSMMAFQSLKLSLNFSVLTCAACAVFVYLASNTQAREFGRAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3K6</accession>
    <name>A0A2S9H3K6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0550</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94547">
        <property type="protein sequence ID" value="PRC94547"/>
        <property type="gene ID" value="S2091_0550"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="14"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="64"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="101"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="183" mass="20823" checksum="ED568C86AAE66F35" modified="2018-07-18" version="1">MSRQILTLPVLCRVLRYGVGTLLIATLIAHFWVWLSLGDVKLGTFTFLIHSGDLDAKELSEMPILIRVLTILVSLPALFFLTVALIRLLRLMHFFEKKEIFVMPSILLLKGFSGAIFLYILCSMVEPVVRMLVFTLVGSTQGQELVLHLTDSFDELLLCGMFYVIVRIMEEGRRLAEENSEFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3M5</accession>
    <name>A0A2S9H3M5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycine/D-amino acid oxidases (Deaminating)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0570</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94567">
        <property type="protein sequence ID" value="PRC94567"/>
        <property type="gene ID" value="S2091_0570"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DAO" evidence="1">
        <location>
            <begin position="51"/>
            <end position="404"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="448" mass="49310" checksum="7AE3EAB522611769" modified="2018-07-18" version="1">MTVSLITRLTNHSKIMKHKHKETRLTKDSFYEASVTREAPLPALDSDISADVCVVGGGLAGLSSALELAQRGYSVVLLEAQLVGWGASGRNGGQALVGFSSDEAIEQQLPLEEGRRLWNMTVEAMQLMRDRISKYNIECDFTPGYLSVAVTDKKARELEEWVNSLEQRYNYSMQHVSKDQIGDWIQSDRYQGGAYDANSGHAHPLKYTLGIAAAARAAGVKVYENSPVVSIDRGAAPLVKTDKGSVRCNFVVLAGNVYLNEYGTTVAPELDKRIMSVGTYIIATEPMEKARADALIKNRAAACDTNFVLDYYRPTADNRMLFGGRVSYSTATPINLVGSMRSRMLSVFPQLSDLEVPYAWGGFVDISMNRAPDFGRVEDNIYYLQGFSGHGLILTGIAGKVVAEAIAGQSERFDAFGKIKHHNFPSGQVMRTAAQVLGMWYYQLKEIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3P1</accession>
    <name>A0A2S9H3P1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Phosphoglycerate dehydrogenase and related dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_0489</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94486">
        <property type="protein sequence ID" value="PRC94486"/>
        <property type="gene ID" value="S2091_0489"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006139">
        <property type="entry name" value="D-isomer_2_OHA_DH_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006140">
        <property type="entry name" value="D-isomer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00389">
        <property type="entry name" value="2-Hacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02826">
        <property type="entry name" value="2-Hacid_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2-Hacid_dh" evidence="2">
        <location>
            <begin position="19"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="domain" description="2-Hacid_dh_C" evidence="3">
        <location>
            <begin position="112"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC94486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="318" mass="34754" checksum="382FF81461CD9367" modified="2018-07-18" version="1">MMKIAILDDVQDVVKNLSCFSLLQDHDVKIFTNSARGIGQVAIRLAPFDAIVLIRERTAMPRALLQKLPNLKLISQTGKVAGHIDLDAAAELGITIAEGIGDPTAPAELAWALIMAAMRKIPQYASNLREGTWQTVSSNPVHNTLGSRLKGKTLAIWGYGKIGQLVAGYGRAFGMQVLVWGREASREKALQDGYVVAASKEEFFTRADVLSLHLRLNEATRGIVLDSDLKRLKPSALFVNISRAELVEEGALLTAVTQGQPAALDVFDAEPLAHDSPLLRLPNVLATPHLGYVEQQSYEIYFEAAFQNIVDYAKRELA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3S6</accession>
    <name>A0A2S9H3S6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">NIPSNAP protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0632</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94629">
        <property type="protein sequence ID" value="PRC94629"/>
        <property type="gene ID" value="S2091_0632"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="110" mass="12486" checksum="9F2D4AC1B36604B8" modified="2018-07-18" version="1">MQRLLEIRLYALSAGSGPRFHQLVSQQSLPLLREWGMDVVAFGLSVSDPDSYFLMRAFDNLEHLTSSQDAFYASEAWRKGPREAIIGLIKSDLSSVLQLNVETIDAMRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H473</accession>
    <name>A0A2S9H473_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glyoxalase-like domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0669</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94666">
        <property type="protein sequence ID" value="PRC94666"/>
        <property type="gene ID" value="S2091_0669"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041581">
        <property type="entry name" value="Glyoxalase_6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18029">
        <property type="entry name" value="Glyoxalase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyoxalase_6" evidence="1">
        <location>
            <begin position="10"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="128" mass="14349" checksum="A63BC6C891A85F5D" modified="2018-07-18" version="1">MKRVTGIGGIFFKAKDPATLLAWYRKHLGINAEQWGGTAFPWTNPDKPVVDGKTVWSVFGEESSCFAPSTSPFMINYRVENLHELLALLRSEGCAVDPKVDESEYGKFGWVMDPEGNRIELWEPPASE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H499</accession>
    <name>A0A2S9H499_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Rhodanese-like domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0009</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94814">
        <property type="protein sequence ID" value="PRC94814"/>
        <property type="gene ID" value="S2091_0009"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="SSF52821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015753337" evidence="1">
        <location>
            <begin position="24"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodanese" evidence="2">
        <location>
            <begin position="281"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="386" mass="42036" checksum="B2D216E2A5B267AF" modified="2018-07-18" version="1">MKIARNIKLCCALLLLLPLLAQAELKILIGVDPADEVGKNNVDRVISSIPELNSALGSKVFSNQSSNLTDVLRSTRTQENDIIIGPPHIIASAISHHYQVLARNEADADFVLIARPDIKKLDDIAGKRLYLTQQDSTRTYVAKGMLIENNIDIKSIKQVTYGKTSGAGLFALAANLTDMTIASREEAQSWILANPGQGVIIKTSRRIPAGMALVVKSDTSEAVRKIILKWASSSTNGVGKFRATTNEDVTQYRYIASLGILTPASLSGVQTVTADEVSKLVAKGVTVVDTRSAKEYQLAHIAGAINAAYVEHSLKERDFDPKLDDYSAIAALPKEKAVIFLCNGTECWKSYKASKIALQLGFTQIYWFRGGMPEWQEKSLPTKTGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4C5</accession>
    <name>A0A2S9H4C5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">HipA N-terminal domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_0035</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HipA Ser/Thr kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94840">
        <property type="protein sequence ID" value="PRC94840"/>
        <property type="gene ID" value="S2091_0035"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012893">
        <property type="entry name" value="HipA-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017508">
        <property type="entry name" value="HipA_N1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13657">
        <property type="entry name" value="Couple_hipA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07804">
        <property type="entry name" value="HipA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Couple_hipA" evidence="4">
        <location>
            <begin position="11"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="HipA_C" evidence="3">
        <location>
            <begin position="161"/>
            <end position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC94840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="422" mass="46594" checksum="BDAC0EE9FB1F1657" modified="2018-07-18" version="1">MNDLPHVKQLVVKYNGLTVGRLHEGPSRGEITFQYDASWLSTGFDLAPNSLAFTALPQTAAHPLFHGLHGAFAASLPDGWGLLLMDREFKRQHGWSPNEILPLDRLAYIGTRAMGALEYHPAIELAITNQVNLAAILKSVDEVVSGTQTDVLTQLRIQGGSPGGARPKVTVARSKNNTEILSGFNTIPEGYEHWMIKFRGADDPVDMGRIEMAYADMAVAAGIEMPETELIRVPKINVKPGIDADDYFFAVRRFDRIGNRKLHVIALDAILYADYRIPSLDYEIVLGVTQGFTQNAVEVERAFRLACFNTLAHNQDDHGKNFAMLHTDSGWRLAPGYDLTFSTGMGAEHTTAVSGSGKPDRKSLLRLAAAFAIKTKRANEIIEQVFEAVKRWHQYSAKYGVSLESAERIEEALAGVRKIFSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4H3</accession>
    <name>A0A2S9H4H3_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Penicillin-binding protein 1A</fullName>
            <ecNumber evidence="7">2.4.1.129</ecNumber>
            <ecNumber evidence="6">3.4.16.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="26" type="ORF">S2091_0779</name>
    </gene>
    <organism evidence="26 27">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="26 27" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="26 27">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="21">
            <text>[GlcNAc-(1-&gt;4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n)-di-trans,octa-cis-undecaprenyl diphosphate + beta-D-GlcNAc-(1-&gt;4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate = [GlcNAc-(1-&gt;4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n+1)-di-trans-octa-cis-undecaprenyl diphosphate + di-trans,octa-cis-undecaprenyl diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23708"/>
            <dbReference type="Rhea" id="RHEA-COMP:9602"/>
            <dbReference type="Rhea" id="RHEA-COMP:9603"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58405"/>
            <dbReference type="ChEBI" id="CHEBI:60033"/>
            <dbReference type="ChEBI" id="CHEBI:78435"/>
            <dbReference type="EC" id="2.4.1.129"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">In the C-terminal section; belongs to the transpeptidase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">In the N-terminal section; belongs to the glycosyltransferase 51 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="26">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.129" evidence="7"/>
    <dbReference type="EC" id="3.4.16.4" evidence="6"/>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94776">
        <property type="protein sequence ID" value="PRC94776"/>
        <property type="gene ID" value="S2091_0779"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008658">
        <property type="term" value="F:penicillin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008955">
        <property type="term" value="F:peptidoglycan glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009002">
        <property type="term" value="F:serine-type D-Ala-D-Ala carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046677">
        <property type="term" value="P:response to antibiotic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3810.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001264">
        <property type="entry name" value="Glyco_trans_51"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023346">
        <property type="entry name" value="Lysozyme-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036950">
        <property type="entry name" value="PBP_transglycosylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031376">
        <property type="entry name" value="PCB_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001460">
        <property type="entry name" value="PCN-bd_Tpept"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17092">
        <property type="entry name" value="PCB_OB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00912">
        <property type="entry name" value="Transgly"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00905">
        <property type="entry name" value="Transpeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53955">
        <property type="entry name" value="SSF53955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="18" id="KW-0046">Antibiotic resistance</keyword>
    <keyword evidence="9" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="14" id="KW-0133">Cell shape</keyword>
    <keyword evidence="20" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="11 26" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="13 26" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="22" id="KW-0472">Membrane</keyword>
    <keyword evidence="19" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="16" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="10" id="KW-0645">Protease</keyword>
    <keyword evidence="27" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="15" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="26" id="KW-0808">Transferase</keyword>
    <keyword evidence="12 22" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="17 22" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="22">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="domain" description="Transgly" evidence="24">
        <location>
            <begin position="67"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="domain" description="PCB_OB" evidence="25">
        <location>
            <begin position="328"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="domain" description="Transpeptidase" evidence="23">
        <location>
            <begin position="434"/>
            <end position="678"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00007739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00012555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00018638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00023251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00023988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="Pfam" id="PF00905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="24">
        <source>
            <dbReference type="Pfam" id="PF00912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="25">
        <source>
            <dbReference type="Pfam" id="PF17092"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="26">
        <source>
            <dbReference type="EMBL" id="PRC94776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="27">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="767" mass="84404" checksum="04050B7D12741807" modified="2018-07-18" version="1">MINFFHPLSTKRFLRGLLRLSIGLFVLAIVAAIVTVALLYPSLPELDSITSYRPKMPLRVFSADEVLLAEFGDERRNVTPLKDIPLIMKQALLAVEDQHFYEHNGIYIVGNFRALLHNMTNFSGGPKQGASTITQQVARNFFLTNEQTYHRKIIEALLTYKIEKNLTKDQILELYMNQIYLGQRAYGFASAAQIYFGKKLQDITPAEAAMLAGLPKSPARINPITNYPRAKTRQLVVLQLMRQLNYITEDQYQQAKVQPLLLKTSNNEFGIHAEYVAELARQAVQDEFKADSYTRGINVYTTILKEDQIAAYTALRKGVMDYEKRHAYRGPEAYLDLPDDSDDADELIETAFSNYPANDDFLSAVVLESTPKKVVVVASSGEEITITGGGLSFAASGLANNASSKIKIKRGAVLRVIQDGKNWSITQLPEVESAFVAADTNTGAIRALVGGFDFKRNQFNHVTQAWRQPGSTFKPFIYSASLEKGFTPATIINDAPLTFDATQTGGLAWEPKNSDDQYDGPITMREALAKSKNMVSIQILENIGVNYGQEFAMKFGFDADKNPPYLPLALGAGAVTPLQMAAAYAVFANGGYKIKPYLISKITDASGTVLHQTDVPKPGMESNRIISEGNAFMMDNLLKNVVKNGSASRALVLNRPDLAGKTGTTNNAYDAWFAGYQSRIVAVAWIGFDQPKNLGSREFGGGLALPIWISYMQTALLHQPIEDRPVPPTVSLVDGDYSYTEPPTAIVRSIGVNPAAASMPVASPVLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4I0</accession>
    <name>A0A2S9H4I0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putative threonine efflux protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_0090</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94895">
        <property type="protein sequence ID" value="PRC94895"/>
        <property type="gene ID" value="S2091_0090"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001123">
        <property type="entry name" value="LeuE-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30086">
        <property type="entry name" value="PTHR30086"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01810">
        <property type="entry name" value="LysE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006324">
        <property type="entry name" value="LeuE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="42"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="127"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="156"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="189"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC94895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="212" mass="22384" checksum="E20016237E978EBA" modified="2018-07-18" version="1">MLLTPEQFFGFLAAALLITVSPGPDNLMVLGVGISRGRKQGMAFGLGCALGCLSHTLLAALGISALIAASPIAFSALKIAGGLYLIYLGVQALRSSGLSTPTKLGATSMSEETLLKLFSKGLIANSINPKVVLFFLSFLPQFVLQKNGHIGWQTAQLGLIFTAQGVLLFSLLGYFSGAVGQWLNQRPKAGLWLDRVAGSIFIALGLRLVFTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4J3</accession>
    <name>A0A2S9H4J3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0094</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94899">
        <property type="protein sequence ID" value="PRC94899"/>
        <property type="gene ID" value="S2091_0094"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002656">
        <property type="entry name" value="Acyl_transf_3_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01757">
        <property type="entry name" value="Acyl_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="105"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="157"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="181"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="223"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="254"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="283"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="316"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="354"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl_transf_3" evidence="2">
        <location>
            <begin position="24"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="406" mass="45547" checksum="FF2B97AAB5B616AB" modified="2018-07-18" version="1">MNNGKTNKSTLEKSMMQNQTANRIHGLDTLRAAAILLVLMYHYMVVVSASNPFGFFGEIGWTGVDLFFVLSGYLIGNQILSAYAQNRKFPLTTFYIKRLLRTLPNYYFILAMYFLFPLALGGTTAASLWQFLTFTQNLGMRPGETFTHSWSLCIEEQFYLILPIVVIFLFSVITSIKRSIWLAWLVIVAAIVAGMVVRGMAWFDYGHSAITGFDYYQHIYYSSFARFDELLPGVAIALLKNYHTETYTKILRKGNALLVAGLMAVATMFYLLSQFLYTENAGFSFYLTTFGYPLLATSFAILTLAALSPASLLNRIQIPGAASIALWSYAIYLAHKPIFKVLKAPLVKLNIDTASFWGIAIIMTVSILGGWLLYRLIETPFMKLRARLYSTDSANKLGAGLNLSAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4P6</accession>
    <name>A0A2S9H4P6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Virulence-associated protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0155</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94960">
        <property type="protein sequence ID" value="PRC94960"/>
        <property type="gene ID" value="S2091_0155"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007159">
        <property type="entry name" value="SpoVT-AbrB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037914">
        <property type="entry name" value="SpoVT-AbrB_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04014">
        <property type="entry name" value="MazE_antitoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00966">
        <property type="entry name" value="SpoVT_AbrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89447">
        <property type="entry name" value="SSF89447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51740">
        <property type="entry name" value="SPOVT_ABRB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SpoVT-AbrB" evidence="2">
        <location>
            <begin position="5"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51740"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="80" mass="9220" checksum="B6E0E613BA5B0E63" modified="2018-07-18" version="1">MPTTAKLFTTGRSQAVRLPMEFRFQGNEVFIRRNPETGEVVLSPKPASWEDFFELAKRTDIPADFMSDRDDPPAVERDLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4Q5</accession>
    <name>A0A2S9H4Q5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Oxalate/formate antiporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_0159</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94964">
        <property type="protein sequence ID" value="PRC94964"/>
        <property type="gene ID" value="S2091_0159"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019531">
        <property type="term" value="F:oxalate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026355">
        <property type="entry name" value="Oxa/Form_antiport"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04259">
        <property type="entry name" value="oxa_formateAnti"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="60"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="87"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="112"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="144"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="176"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="226"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="260"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="303"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="326"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="366"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="391"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="19"/>
            <end position="415"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC94964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="438" mass="47391" checksum="2FE042861AF4B715" modified="2018-07-18" version="1">MTVHSLHPPAVTKFNSSNRWLQLILGIVCMAMIANLQYGWTLFVNPLDQKYHWGKAAIQTAFFIFVLTETWLVPVEGYLVDRFGPKLVVMAGGLLVGLAWVMNAFAASLTVLYIAAAIGGVGAGAVYGTCIGNALKWFPDRRGLAAGLTAAGFGMGSALTIIPISMLIKSSGYETAFLYFGIGQGLIVFLFSFFLLTPQKGAVPHVAKVVQSSVNFTWQDMLKSPVFWLMYLMFVLMAAGGLVATAQLGPIAKDFNIADIPVSILGLTLPALTFALSIDRVFNGFTRPFFGWVSDHIGRENTMFIAFSLEALGIVMLFQIGHDPFWFVVLSGLVFFGWGEIYSLFPSTCVDTFGSKFATTNSGLLYTAKGTAALLVPFSSMLVAATGSWHAVFYVAAAMNMTAALLAILVLKPMRARMANLRPVATEFSLNEAVVVNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4Q7</accession>
    <name>A0A2S9H4Q7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0165</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94970">
        <property type="protein sequence ID" value="PRC94970"/>
        <property type="gene ID" value="S2091_0165"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="66" mass="7609" checksum="A06A92AA95A2373F" modified="2018-07-18" version="1">MKIIIGVVFHSYADYKMSISVHAIKRKKILRFFTILEASLRRYVHTATQLGYSVIRDKEGLPGANR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4R6</accession>
    <name>A0A2S9H4R6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC-type sugar transport system permease component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_0169</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94974">
        <property type="protein sequence ID" value="PRC94974"/>
        <property type="gene ID" value="S2091_0169"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008643">
        <property type="term" value="P:carbohydrate transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="14"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="87"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="116"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="149"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="193"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="252"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="81"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC94974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="288" mass="31462" checksum="2CA774CEF25B7950" modified="2018-07-18" version="1">MQANSTKFSLGRGIIYLLLILCALYYLVPLYVMLTTSVKSLDEIRSGNLLDFPLNPNSAAWAKAWGSACTGVQCNGLAPYFWNSVKMAVPAVLISTLIGSLNGYVLAHWRFRYSEIFFTGLMVGCFIPFQVVILPMARLLGLLGIANTTGGLIVVHIIYGIAFTTLFFRNYYVTVPEELVKAARIDGAGFFTIYSRIILPLSLPIFMVCFIWQFTQIWNDFLFGVVFGGADAQPVTVALNNLVNTSTGITEYNVNMAAAIIAALPTLGLYLLAGKYFVRGLTAGAVKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4V4</accession>
    <name>A0A2S9H4V4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NADH(P)-binding</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0207</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95012">
        <property type="protein sequence ID" value="PRC95012"/>
        <property type="gene ID" value="S2091_0207"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="1">
        <location>
            <begin position="5"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC95012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="314" mass="35214" checksum="189D872DA311FFEF" modified="2018-07-18" version="1">MSKNILIIGGTRFFGKVLVQKLLDAGNQVTIATRGQMKDSFDYSVQRIKVDRKNEASMLEAFAGISGFDIVYDQMCYTPRDAAISVKTFAGKVGRYVVSSTIEVYDHLYRKFDRPYREVDLDLNSVAVDMTHPWDIAELAEQHYGLGKRQAEAYFYQEGSLPVVSVRIAHVLAGPEDFTGRLAAYVQRVYQGDPVLYSNGHGKSSFTNPEAICDFLCWVGEETFLGPINSASVGEFSALDIYREVGELMHKDIVSQPVVCQINAPQLSPFDYSHLHMMDTSRAQSLGYSFNHRREWLAELISQHIAAESKAAQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4Z2</accession>
    <name>A0A2S9H4Z2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Efflux transporter, RND family, MFP subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_0141</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94946">
        <property type="protein sequence ID" value="PRC94946"/>
        <property type="gene ID" value="S2091_0141"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006143">
        <property type="entry name" value="RND_pump_MFP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01730">
        <property type="entry name" value="RND_mfp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015647444" evidence="4">
        <location>
            <begin position="22"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="domain" description="HlyD_D23" evidence="5">
        <location>
            <begin position="70"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="140"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="356"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="112"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="152"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="374"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC94946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="393" mass="41994" checksum="D4225C81A5235F89" modified="2018-07-18" version="1">MLPYSRSTLFVSTTLAIAAFACLSGCNNASSKSDKATVADILLIAPEDLTTIHTNAFASGPSITGSVQPERKADLRAEISSVVLQVLKENGEKVKKGDLLVRLDDTSIRDSLNSAQESERAATQSLEQAQRQYERLKTLRGSGMASAQQVEDAEIRRNTGQSDLSAANTRTVQARQQLQRTEIRAPFDGIISERKVSNGDTAQIGKELVKVIDPTSMRFEGLVSADTVSQVKIGQAVNFRINGYNGQNFNGTVKRVNPEANPVTRQVEVLVSFSDSAQPQVSGLYAEGQIEAGSIATLMIPEMSIVRNGDKTTAWTVKDNAIHKTIIALGARDLRRGDYVVKSGLSDGDILLRNPSTTLKDGQKVDASNKPAAKPAAATTSATAVATSDSTGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4Z3</accession>
    <name>A0A2S9H4Z3_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">UPF0313 protein S2091_0255</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_0255</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="6">Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the UPF0313 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95060">
        <property type="protein sequence ID" value="PRC95060"/>
        <property type="gene ID" value="S2091_0255"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01251">
        <property type="entry name" value="UPF0313"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020612">
        <property type="entry name" value="Methylthiotransferase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023404">
        <property type="entry name" value="rSAM_horseshoe"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022946">
        <property type="entry name" value="UPF0313"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024560">
        <property type="entry name" value="UPF0313_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013704">
        <property type="entry name" value="UPF0313_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32331">
        <property type="entry name" value="PTHR32331"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11842">
        <property type="entry name" value="DUF3362"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08497">
        <property type="entry name" value="Radical_SAM_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01069">
        <property type="entry name" value="UPF0313"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03904">
        <property type="entry name" value="SAM_YgiQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01278">
        <property type="entry name" value="MTTASE_RADICAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="4 6" id="KW-0408">Iron</keyword>
    <keyword evidence="5 6" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="8">
        <location>
            <begin position="385"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="713"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="748"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="399"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="403"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="406"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC95060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="783" mass="86739" checksum="EAE288219448F309" modified="2018-07-18" version="1">MTAPENLFSYPAYREKTAKPAPFLPMSRAEMEVLGWDSCDVILVTGDAYIDHPSFGMALVGRLLESHGFRVGIISQPDWRSVDAFRTLGKPNLYFGITAGNMDSMVNRYTADRKIRSDDAYTPHGEAGKRPDRAVMVYGQKVREAYPGVTVVAGSIEASLRRIAHYDYWSDTVKRSILLDCKADILLFGNAERALLSLTHRMAAGEKVSTIRDLRGSAFIVPSGWKPNADWIETNSVKVDTPGKIEEHIDPYMMTGVESNETCATTSSNAASAAEIEAATIKPIKIVSREERLANSIAIREKTVLRLPSYDEVKDNPVLYAHTSRVFHLDSNPGNARALVQGHGNRDVWMNPPPLPLAMDEMDGVYDMAYARAPHPSYGNAKIPAWDMIRFSVNIMRGCFGGCTFCSITEHEGRIIQSRSEPSILKEIEEIRDKVKGFTGVISDLGGPTANMYRLACKEKSIEESCRRLSCVYPSICSNLGTDHSKLISLYRKARALPGIKKILISSGLRYDLAVKSPEYVKELVTHHVGGLLKIAPEHSEAGPLSKMMKPGMGAYDEFKAMFEKYSKEAGKQQYLIPYFIAAHPGTTDDDMLNLALWLKKNNFKLDQVQTFMPTPMALATAMYHSRKNPLKKVTEDSEVVETVRTGRIRRLHKALLRYHDQDNWPIIREALVRMGRRDLIGSGDKHLVPSEHSPLAVKLAAVKRHQKPMVMNSAKNGADPRFATGAPLSNKSAKVNRHEGSNKVAGKSSVAVKSTARPSQPARKPTAQISAVKRAASKISGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H558</accession>
    <name>A0A2S9H558_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="10">TonB dependent receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">S2091_0314</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95119">
        <property type="protein sequence ID" value="PRC95119"/>
        <property type="gene ID" value="S2091_0314"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039426">
        <property type="entry name" value="BtuB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30069">
        <property type="entry name" value="PTHR30069"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="3 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 10" id="KW-0675">Receptor</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0798">TonB box</keyword>
    <feature type="domain" description="Plug" evidence="9">
        <location>
            <begin position="77"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="8">
        <location>
            <begin position="302"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="315"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC95119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="725" mass="79338" checksum="0F382219EB5E9CD6" modified="2018-07-18" version="1">MRKMIFLNDVSKDVIRLPAATPNRLTVLSWSVAMALAGAPVMAQELMQDLAQEREEEIAEESDVVTTIVITGIASDRNDVANPVSVLKGRKLLLRSEATLGETLSSELGITASHFGVGASRPVIRGMDGARVKVLTDGSEVQDASTISPDHAVALEPLLAQQIEVIRGPSALAYGGGVAGGAVNVLDNKIPTKIPDNNIEGTINVRANSAANETAGAVELSAGSGNMAFHVEGLKRNSGDYRVGSDWSQGSKVNDSYNKSDTGSVGMSWIGAQGYLGVAYTQQNNNYGLPGHSHSYGGCHVHGTQLHCGAHEHGYSHGHDHDHDHNHDHEHGDEHEHAAPFVKLTSKRWDLRGEYREPLAGIAKISLRGGLTDYQHREIEGDLVATTFKNQAHDLRMDIEHKPFADFRGVLGVQTSRRDFSAVGEEAYVAPTITAKHGMYLLEEYRWHDWRFEGALRQEWQRTELEVPAMTRSHHGTSASLGANWAFTPGYALGMTMTRAQRLPTAEELYADGLHLATNTYELGDADLKPETSQNIDITLRKTEGPTTFSAALFYNRINNYIYGRTLDVYKDLQLLQYTQQDASFVGMEGQVRRQFTPHLGVTLFGDVVRAQLQSAQDGNGNLPRIPSARFGTRADLSSGPWSGQLEWVRVAQQNKVANFESPTPGYSMLNLELAYSGKIHAQHYTLYAKANNLTNVLAYSNTSFIKDAAPLMGRNLTVGVRVLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H577</accession>
    <name>A0A2S9H577_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0323</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95128">
        <property type="protein sequence ID" value="PRC95128"/>
        <property type="gene ID" value="S2091_0323"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015727305" evidence="2">
        <location>
            <begin position="33"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="32"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC95128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="536" mass="57802" checksum="58C8A3EDA59816A5" modified="2018-07-18" version="1">MLKQTSAHFFKVVSKLYLILGIMLAPIPEAIAADDSRTNAELLQEIEQIKARLKQLEELVHKNADGVETAKQTAQQALTKETLVTDKLANGQIPLGHTNLSFSGWLQGTMTWRDHNELASASSTNFGTPFPKSIAYGVHELRADARNSYFALNMKSAEVDDVKLSGRLEVDFQSIGSNTTQNNNGWAPRLRHAFVEVDNAATGWHFVAGQTYALTTPYGNQVRSDGSPSADKAWTMLPSLPIINVGQLDDIGPAGVNSPRPLEFRLIKTFYNTALAVSLDSQIVSWAGNIAGASPVYTGTTLSSAANNQFNNNATQNLSLSTVPDVLMKATWQPDPSTFYETFGIVRSYRDMNGTTNLTGTGTTHGFGGGVDSFIKLWPGKLDITGGIGYGSLGGYAGNGIADVTFDATGKPTVVKEMQGWIGVLAHPSRELDLIAYAGTEHSHSAGVSGTDYGWGNPNFLNSGCAILNGVCNGSVKAVADVEVGAIWRFYNGSFGHVDFMPQITWLKKSLFSDINDFAPSAHNVAVDLTIRFYPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5F3</accession>
    <name>A0A2S9H5F3_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 12">UDP-3-O-acyl-N-acetylglucosamine deacetylase</fullName>
            <shortName evidence="12">UDP-3-O-acyl-GlcNAc deacetylase</shortName>
            <ecNumber evidence="4 12">3.5.1.108</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">lpxC</name>
        <name evidence="13" type="ORF">S2091_0392</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 12">Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11 12">
            <text>a UDP-3-O-[(3R)-3-hydroxyacyl]-N-acetyl-alpha-D-glucosamine + H2O = a UDP-3-O-[(3R)-3-hydroxyacyl]-alpha-D-glucosamine + acetate</text>
            <dbReference type="Rhea" id="RHEA:67816"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:137740"/>
            <dbReference type="ChEBI" id="CHEBI:173225"/>
            <dbReference type="EC" id="3.5.1.108"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 12">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 12">Glycolipid biosynthesis; lipid IV(A) biosynthesis; lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 2/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the LpxC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.108" evidence="4 12"/>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95197">
        <property type="protein sequence ID" value="PRC95197"/>
        <property type="gene ID" value="S2091_0392"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00359">
        <property type="reaction ID" value="UER00478"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008759">
        <property type="term" value="F:UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0103117">
        <property type="term" value="F:UDP-3-O-acyl-N-acetylglucosamine deacetylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009245">
        <property type="term" value="P:lipid A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1700.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00388">
        <property type="entry name" value="LpxC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004463">
        <property type="entry name" value="UDP-acyl_GlcNac_deAcase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011334">
        <property type="entry name" value="UDP-acyl_GlcNac_deAcase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015870">
        <property type="entry name" value="UDP-acyl_N-AcGlcN_deAcase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33694">
        <property type="entry name" value="PTHR33694"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03331">
        <property type="entry name" value="LpxC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00325">
        <property type="entry name" value="lpxC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 12" id="KW-0441">Lipid A biosynthesis</keyword>
    <keyword evidence="5 12" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="10 12" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 12" id="KW-0862">Zinc</keyword>
    <feature type="active site" description="Proton donor" evidence="12">
        <location>
            <position position="268"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="78"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="241"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="245"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00024535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PRC95197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="311" mass="34178" checksum="F73F102648A8B040" modified="2018-07-18" version="1">MLKQRTIKTIAKTIGVGLHSGTKVELTLRPAEIDVGIVFRRVDLDPPVEFPASALGVGDTRMASTLTQGGVKISTVEHVMSACAGLGIDNLYIDVSAEEIPIMDGSASSFVYLLQQAGKEEQEAAKKFIRILKPVEVREGAGATEKWARLDPYHGYKLKFFIEFNHPAVDGTNQTAEVDFGSVSYVKDVARARTFGFMQDVESLRGIGLARGGSFENAIVLDEFRILNADGLRYEDEFVRHKILDAIGDLYLIGHPLLASYSAHKSGHGLNNQLLRALLAQPDAYEIISFDSMELAPHSYLKQVAEQWLPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5K6</accession>
    <name>A0A2S9H5K6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0416</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95221">
        <property type="protein sequence ID" value="PRC95221"/>
        <property type="gene ID" value="S2091_0416"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008023">
        <property type="entry name" value="DUF748"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036737">
        <property type="entry name" value="OmpA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05359">
        <property type="entry name" value="DUF748"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103088">
        <property type="entry name" value="SSF103088"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC95221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="1219" mass="131761" checksum="7CBA71EC2AC74084" modified="2018-07-18" version="1">MKNILTFSRSSRLLRWFISGICVVLLLALISWLTVPSYLKKTLEQQVEVATGRQFKVGEVAFNPFTLTVQVSHFVLYEADKKTPAFSADNLLLKASPASVFRLAPIVREVVLTHPSLQLVRSQHDGQEVTNFSDVIARLAEHPSTGEPLRYSVSNIQLNNGAIHLDDQIAGKQIQIDALTIGLPFLSNFTGAIDAFVEPSLSAKINGSLFELKGRSKPFFITHETSLAIDFNQFDLTQLIAFSPTPLPFKVSSAKFSSNLTLNFSAQKDAEHINLSGTASLTDVAMADLAGAPLFKAQAINVNIHEANLVTDNVALDSLEIKEPQVWAGLNQQGMLNWLALQTNKKTVVVKTAEPEHVSAANTSKPLFDLAHFQLKNGTVHWSDAANATPTMELQLANVNVDAQKISTNEKANPAKLSWSFGEAGQQQVHFVGTVDATHAAVAGQLTLSDLALADYQPYVNRIMAANVSGKLSLQTQIEAKNGNLSLSEFSGALEDLKLQATKSEYGGMSAKKIAIEKLALNTETKQAKIEQIQLEHVQGDIFRGADGGLNFSHMLKKVAAKNEVQPAAQGSTKSVTKPAAKSPEWQADINQIALTDSNFVFGDKSVQPAVSIRADSVEAQLEHVTSKFAQPINMTMRATLNKSGKFSVQGSVAEKAMQLKVEVQNFALAALQPYFTEFLNITLATGSVSTKGQLAWKAPSEVTYQGLLKLANLRTQDKENSDDFLKWKMLEIGGINVALGGQQQSITLGKIDLTDFYARAILSEQGKLNLQNIVVHQQADAKADAKTDIKTDAKPQPVILPQTTATASVSTPAAAPAPANSPIINIGQINFNNGIINYTDNFIKPHYSMRMTGMKGSVGAIHSNVAQAAPINLDGKIDNDAPIAISGSLNPLFTPMLLDIKLTASGVDLPRLTAYSAKYAGYPIIKGKLSLDVQYHIQNNQLAANNTLKIDQLTFGDKVDGPDATHLPVPFVVSLLTDLNGQINLDLPISGTLNDPEFSIGGLIFKVFINLIGKVITSPFSLLAHSFSGGEELAYIEFPSGSAKLTDASKAKLDSLAKALEQHPNLKLDIIGRADLTADTSGLRTAMLAKQIQKSKDVKEESDAAAVDADTKPLSDAERAKAIDKIYSAAKFDKPRNMIGFAKSLPTAEMESLIISNTKISEDDIRALAVRREATVQNYLSVTNHVGADRMFSIAPKLNGDDIKDKGAVTRVDFELKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GS93</accession>
    <name>A0A2S9GS93_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4732</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000057">
        <property type="protein sequence ID" value="PRC90558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90558">
        <property type="protein sequence ID" value="PRC90558"/>
        <property type="gene ID" value="S2091_4732"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC90558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="62" mass="6739" checksum="FF777C18D4A5A6CE" modified="2018-07-18" version="1">MHRLMRSQHAVQCTSLFIPYSLRLASIGIMGGLNVGRFTNYGKTDAKQNADGTTAQQSKVPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GS97</accession>
    <name>A0A2S9GS97_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4701</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000046">
        <property type="protein sequence ID" value="PRC90594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90594">
        <property type="protein sequence ID" value="PRC90594"/>
        <property type="gene ID" value="S2091_4701"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC90594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="66" mass="7215" checksum="B0027C780AEF4DC0" modified="2018-07-18" version="1">MNNVISLDAARQRRFHIQLAKSSEDWQDICASFALSGVILDDGDAERAGRVMAGQATTHSVLQDIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSF7</accession>
    <name>A0A2S9GSF7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Short-chain dehydrogenase of various substrate specificitie</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4664</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000042">
        <property type="protein sequence ID" value="PRC90628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90628">
        <property type="protein sequence ID" value="PRC90628"/>
        <property type="gene ID" value="S2091_4664"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="257" mass="27820" checksum="57683BD8805E3B57" modified="2018-07-18" version="1">MQNVFITGASSGIGAALARQYAQQGACLGLVARRLEILEELRQSLPHPERHHVYALDVTNHAALAAAAAEFNQATGGANIVIANAGISRGTLTEYTEDLPVFEQVVATNLLATVATFAPFIQDMKTRAAQQTCRLVGIGSVAGIRGLPGAEAYSASKAAVISYCESLRVELRASKIKVVTICPGYIDTPMTQVNSYAMPFLMPVEKFALKTCAAIQRGDSYRIIPWQMGWVAKLLRLLPNWIYDAVFANAPQKTREH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSQ7</accession>
    <name>A0A2S9GSQ7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Bacterial-like globin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_4569</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000037">
        <property type="protein sequence ID" value="PRC90743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90743">
        <property type="protein sequence ID" value="PRC90743"/>
        <property type="gene ID" value="S2091_4569"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019825">
        <property type="term" value="F:oxygen binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.490.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009050">
        <property type="entry name" value="Globin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012292">
        <property type="entry name" value="Globin/Proto"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001486">
        <property type="entry name" value="Hemoglobin_trunc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01152">
        <property type="entry name" value="Bac_globin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46458">
        <property type="entry name" value="SSF46458"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015418036" evidence="4">
        <location>
            <begin position="28"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC90743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="157" mass="17240" checksum="297B0E0E9538AB53" modified="2018-07-18" version="1">MKRFFQSTTALFTLLMSATLMTSTAYAQSSPAPVMNAEKNDAVFQSFGGKAGISKIIDDFLVIWHADPRISAKLEDADVPHLALLLKEQITHLTGGPGVYSGKDMKTVHDGMNLRNVDFNALTEDLQHAMDKNDVPSRAQNKLLAKLAPMQHDIVTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSR6</accession>
    <name>A0A2S9GSR6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4501</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000036">
        <property type="protein sequence ID" value="PRC90753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90753">
        <property type="protein sequence ID" value="PRC90753"/>
        <property type="gene ID" value="S2091_4501"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="56"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="107"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="132" mass="14522" checksum="3E2D1EAB4C83DEAA" modified="2018-07-18" version="1">MIELEVRPQSEKHSGVRHVFIIVQSIIAILLVSVAVGFIMLWLFSVVLSFTPNSVLLPWVAAGVSAFGLLYIFIAAVPGIPGIIWVSRLADHVTPPWDRIFKFVVKIGKISFKVGAIAAILLLVFVIINSMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSW4</accession>
    <name>A0A2S9GSW4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4470</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000035">
        <property type="protein sequence ID" value="PRC90807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90807">
        <property type="protein sequence ID" value="PRC90807"/>
        <property type="gene ID" value="S2091_4470"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018721">
        <property type="entry name" value="DUF2252"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39441">
        <property type="entry name" value="PTHR39441"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10009">
        <property type="entry name" value="DUF2252"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC90807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="405" mass="45467" checksum="FB95DD034F9A70DD" modified="2018-07-18" version="1">MIDVVQCIADFNSKRDPERVAMKYHNMRTNPFVFLRGTCHLFYERLPKNSIFKSAPLTWNCGDMHLENFGSYKGDNRLAYFDMNDFDEAALAPLSWELVRLLTSILIGAESLSASQYEAYALCETLVDAYAKALTTGKSTWVERETSHGIIHQLLNDLRDRQRPAYLDKRTTAKGRGKNKTRTINIDGKKALAATAQQRAIVTKVINDYASTQPNPEFFEVLDVARRIAGTGSLGVDRFVILVKGKGSPDGNYLLDLKNAMPSTLVSNLKTRQPKWETEAHRVVDIEHRMQSVSMAFLTAVKIGNEGYILRALQPSEDRISLNRNQHTMQELHKTVSCLANIVASAHLRSTGRDGSAIADELIAYGHKNKWRSKLLKAAQECAQQVENDWGVYCTAYDEGAFKVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GT01</accession>
    <name>A0A2S9GT01_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Four helix bundle sensory module for signal transduction</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4494</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000035">
        <property type="protein sequence ID" value="PRC90831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90831">
        <property type="protein sequence ID" value="PRC90831"/>
        <property type="gene ID" value="S2091_4494"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="215"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="244"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="443"/>
            <end position="464"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="473" mass="51998" checksum="244AE0E6D3767393" modified="2018-07-18" version="1">MTSTTIIPAQPATGLNLPISSAGNLADVPRQLWLRQAVIIGVTLLVALIGFKTYQTYANVVQTIGKDSVPSIVAAEKIRTQLALAHTEIVNAFLIKETGDAGPSRQAYKKAIDQSYDSLVEASQNITYGDDERQPILAVMTQLFEYQRIIGMANEAGMHEAAGTDVTDSRDVQLLGQADALMREHILPSVVGLDQANFKHLDAAFTEGRQTASHWLYAFIAVSLILGIILLETQFKLYANFRRLLNPAMAFGLAVFVISIIVFFWHTQSVMSEIRSAKEDAFDSVHALSKAKAIAYSANAQESVYLLLRDKAAKLNQTTLFNDAANQLFSGSIRDIGQLPSDLKLLKNQGLLGDELANITFPGEEAMAKKTLQGWLDYVRIDSQIRELEAAGKHDAAVVLCIGKQPMQSDWAFENFMQALDGTLSINQAQFDDAIARAFKHLAWLWMLLIPIFLGPVIGSVAGLQKRLAEFRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GT44</accession>
    <name>A0A2S9GT44_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phage small terminase subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4447</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000034">
        <property type="protein sequence ID" value="PRC90866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90866">
        <property type="protein sequence ID" value="PRC90866"/>
        <property type="gene ID" value="S2091_4447"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019069">
        <property type="term" value="P:viral capsid assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010270">
        <property type="entry name" value="Phage_P2_GpM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05944">
        <property type="entry name" value="Phage_term_smal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC90866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="238" mass="26213" checksum="BC751A4FD0492FA3" modified="2018-07-18" version="1">MMRTLSPAMRHQARVLAQQAAGNSAPGTVTTGSQYELMLYQLAEDRRRLKQIQSIKSKITLKATLLPNYQEWIDGVLTAGKGGQDDVLTTILVWSIDTGDFERAIQIAGYAVQHKMTLPDQYERDIATMLLDEFSGAYLNGKLADDPLRAVQILSQVNALTDGHDTPDQARAKLHKALAYAQLAVIGEDEKSDLVGTDLAAARAAYDNLQRALTLYEGVGVKKDIERLERRLKKAAST</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GT74</accession>
    <name>A0A2S9GT74_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4389</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000033">
        <property type="protein sequence ID" value="PRC90896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90896">
        <property type="protein sequence ID" value="PRC90896"/>
        <property type="gene ID" value="S2091_4389"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010282">
        <property type="entry name" value="Uncharacterised_HutD/Ves"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37943">
        <property type="entry name" value="PTHR37943"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05962">
        <property type="entry name" value="HutD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC90896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="203" mass="22078" checksum="64AB9AA686EB7FC9" modified="2018-07-18" version="1">MKKLSPADYRSMPWKNGAGTTIEIAVFPEHAKLEDFIWRVSRAQVVSDGGFSHFAGIDRSLALLQGSGMRLSVNEFSLKVDAENNIAIFAGDAATHAELINGAISDFNLMSRRSICSHKLNHWVGAATRQLPVGAVLLYCAQGSGQLRGKNTTYDLDLHEDETLQFSSTEEVNEYTLHSTAGSSFYCVQITMNGDSNANSTVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTG8</accession>
    <name>A0A2S9GTG8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DnaA regulatory inactivator Hda</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4310</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000031">
        <property type="protein sequence ID" value="PRC91014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91014">
        <property type="protein sequence ID" value="PRC91014"/>
        <property type="gene ID" value="S2091_4310"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032297">
        <property type="term" value="P:negative regulation of DNA-templated DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013317">
        <property type="entry name" value="DnaA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017788">
        <property type="entry name" value="Hda"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00308">
        <property type="entry name" value="Bac_DnaA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03420">
        <property type="entry name" value="DnaA_homol_Hda"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bac_DnaA" evidence="1">
        <location>
            <begin position="13"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="domain" description="Bac_DnaA" evidence="1">
        <location>
            <begin position="87"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="227" mass="25165" checksum="7426A6C5774F0C54" modified="2018-07-18" version="1">MKQLLLDLAAENPHTLDTFVVGQNAEAAHLLRLFAQRTPSTYGERAVYLWGENGAGKSHLLHALANTPAARYIQATAVIADFEYSPAVSLYLLDDCQNIASTKQVAAFNLFNQIKEHNAFFVAAGSLPPAILGVREDLRTRLGWGLIYQIHGLTDDDKMAALERAANARGITIPSGVLLYLITHYRRDMPSLSKMLDTLINFSLESKRPITLPILREVMQQQDGYSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTK8</accession>
    <name>A0A2S9GTK8_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transketolase</fullName>
            <ecNumber evidence="4">2.2.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">S2091_4242</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the transketolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.2.1.1" evidence="4"/>
    <dbReference type="EMBL" id="PUGF01000030">
        <property type="protein sequence ID" value="PRC91054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91054">
        <property type="protein sequence ID" value="PRC91054"/>
        <property type="gene ID" value="S2091_4242"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004802">
        <property type="term" value="F:transketolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd02012">
        <property type="entry name" value="TPP_TK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005475">
        <property type="entry name" value="Transketolase-like_Pyr-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005478">
        <property type="entry name" value="Transketolase_bac-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033248">
        <property type="entry name" value="Transketolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033247">
        <property type="entry name" value="Transketolase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005474">
        <property type="entry name" value="Transketolase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43522">
        <property type="entry name" value="PTHR43522"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02779">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02780">
        <property type="entry name" value="Transketolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00456">
        <property type="entry name" value="Transketolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00861">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="SSF52922"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00232">
        <property type="entry name" value="tktlase_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00801">
        <property type="entry name" value="TRANSKETOLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0786">Thiamine pyrophosphate</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TRANSKETOLASE_1" evidence="9">
        <location>
            <begin position="25"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007131"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS00801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC91054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="698" mass="75385" checksum="BA24AEBD66ECA231" modified="2018-07-18" version="1">MPPDITVPATAPALSLDDLCVNTLRFLAVDAVQKANSGHPGLPLGAASMAYVLWTRFLKHNPSNPDWFNRDRFVLSAGHGSALLYSLLHLTGYAVPLDQIKQFRQWGSITPGHPERGVTPGVETTTGPLGQGFANGVGMAIAEANLAARYNQPGLSVIDHHTYGIVSDGDLMEGIASEAASLAGHLQLGKLIYLYDDNHITLSAATDMSFTENCAQRFDAYGWHTQTVVDGNDLMSIENALRRAKAETLRPSLILVRTHIGFGSPHKQDTFAAHGSPLGEEEVRLTKAHLNWPIEPPFYIPDSAQIYFSFALDRGKLAETQWSTTFASYEQEFPELATELRQLMTGNLPIDWDVELPQFPADVKGLSTRVASGKIMNAIAGRLPGLIGGSADLDPSTFTALTNLGDFQPSVSNIISTEDRQGSNGGGWSYSGRNLHFGVREHAMGAIMNGLAAHGGFTPFGATFLVFADYMRPPMRLAALMGLHVIYIFTHDSIAVGEDGSTHQPVEQVASLRAIPRLIVIRPADANETAEAWRMALTSTKQPVALILTRQHVPTLDRIQYASSEGLSHGAYILADAPNGDPDLILIASGSEVGLIVAAREALVKQGLKIRIVSMPSWELFDAQDVDYRNQVLPPSVTARLAVEAGISQGWHRYVGTKGDVLAVDCFGASAPGEEMMLKYGFTVENVCERALAILKSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTQ3</accession>
    <name>A0A2S9GTQ3_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Putative pre-16S rRNA nuclease</fullName>
            <ecNumber evidence="2">3.1.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_4208</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the YqgF HJR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="2"/>
    <dbReference type="EMBL" id="PUGF01000029">
        <property type="protein sequence ID" value="PRC91112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91112">
        <property type="protein sequence ID" value="PRC91112"/>
        <property type="gene ID" value="S2091_4208"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004518">
        <property type="term" value="F:nuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000967">
        <property type="term" value="P:rRNA 5'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd16964">
        <property type="entry name" value="YqgF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00651">
        <property type="entry name" value="Nuclease_YqgF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005227">
        <property type="entry name" value="YqgF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006641">
        <property type="entry name" value="YqgF/RNaseH-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037027">
        <property type="entry name" value="YqgF/RNaseH-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33317">
        <property type="entry name" value="PTHR33317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03652">
        <property type="entry name" value="RuvX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00732">
        <property type="entry name" value="YqgFc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00250">
        <property type="entry name" value="RNAse_H_YqgF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="YqgFc" evidence="3">
        <location>
            <begin position="7"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC91112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="132" mass="14428" checksum="C122BE530061A457" modified="2018-07-18" version="1">MCALTATTLLAFDFGLKRIGVAVGNTFLKQAQALTVISAESNQAKFDAIALLLKEWQVTHCVVGLPSHPDGAEHEMTVRCRRFSNQLEGRFGVTTTLVDERYTSAVISAKRGEVIDAQAAALILQQYFDENP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTQ4</accession>
    <name>A0A2S9GTQ4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="10">TonB-dependent Receptor Plug Domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">S2091_4193</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000029">
        <property type="protein sequence ID" value="PRC91097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91097">
        <property type="protein sequence ID" value="PRC91097"/>
        <property type="gene ID" value="S2091_4193"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="3 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 10" id="KW-0675">Receptor</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="2 6" id="KW-0798">TonB box</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015655576" evidence="7">
        <location>
            <begin position="30"/>
            <end position="972"/>
        </location>
    </feature>
    <feature type="domain" description="Plug" evidence="9">
        <location>
            <begin position="55"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="8">
        <location>
            <begin position="394"/>
            <end position="970"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC91097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="972" mass="103538" checksum="0E593991D49A14EA" modified="2018-07-18" version="1">MKYEQKVGVTAVQLALALLASSAMISAHAQQAQDADVHVEKVYVTGSNIKTIDAETASPVQIIKREDIARQGVTNISDLIANTAASSSQGNLTDISGNGSFAPGGSEVSLRNLGAQSTLVLVNGRRIASFGFANFTEVFSNVDSIPIDAVERVEILKSGASAIYGSDAVAGVINIITRQNFQGVEVNADGQKSLQSHTFGTNKASITAGFGDYANDGFNILVNADVFKRQSVMWSDVQQYTNPSLISTSSAYGALSTYSHGNLIDGANSAPLPGCDPSLIQGGLCKYNRSQQSQAVPDANRINFYSTGTFNLGGGTQAFTEVSLSRGKTDYIAPVPLYGAQAPVTWGNPSTGQPLTFNYLGLSLNDPINTTGDDGSELRFRFLDAPSYNDVVGTQYRVLGGLRGTVNAFDWETAAGIMGSKVTSTTQGAFSSSGFIQEIGNYNNFYPNSNPNVGLSYNATDPNFFNQPGGYRAGGQNSATVLNTLFPKFVSTGQTQAEFVDAKITGPIYSLPAGQINVAIGGELRHESMILGDSNNLQTGDIVGYGISEANSSRNIESLYSEFNIPVLKNFEVIPALRLDKYPNLSSHFSPKLAALYSPTDSLKIRASLEHGFRAPNLIESANSKKFAFDSGVQDPLRCAQATQLSNDLYTAANNPALTPTQASLIAARALAVQGNECSVSVPDQVSNNPELKPETAKSYSLGLVFEPVKGYATSVDFFSIDRSNVIGLQGAQQLVNDAATGNTPAGSTVIRRPLNTAADQSFSSNDPALGGQNDFTVYGVNSGSLQQIVRAMQNISEQKTSGLDIAFQGKQSLGEYGNFREILDSTYTLKFYDTSVSTLSDNLVGSYLIPHFAGSLTLVWDFKKFSNSLRFNYTGGYNEQAGLPDTAWNLAGCAGNNLTAAQCRVASNRTTDYAISYTGIQNLTLGLNIINLFQQKAPVDVKAFGVGATFGTNMQDAEGRMLNLSVNYKFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTZ3</accession>
    <name>A0A2S9GTZ3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4073</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000027">
        <property type="protein sequence ID" value="PRC91178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91178">
        <property type="protein sequence ID" value="PRC91178"/>
        <property type="gene ID" value="S2091_4073"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="30" mass="3257" checksum="4B3818C6FCFC7628" modified="2018-07-18" version="1">MDITYLIGIFLFAAITLLIIKGCSRLGGDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GU16</accession>
    <name>A0A2S9GU16_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Rrf2 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4098</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000027">
        <property type="protein sequence ID" value="PRC91203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91203">
        <property type="protein sequence ID" value="PRC91203"/>
        <property type="gene ID" value="S2091_4098"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000944">
        <property type="entry name" value="Tscrpt_reg_Rrf2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33221">
        <property type="entry name" value="PTHR33221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02082">
        <property type="entry name" value="Rrf2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00738">
        <property type="entry name" value="rrf2_super"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51197">
        <property type="entry name" value="HTH_RRF2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="152" mass="16741" checksum="D72F5A9B16EBECCB" modified="2018-07-18" version="1">MQLTHFTDFGLRILIYLTGVPDGEVVTIKEISAQFNVPQNHLNKIANRLGKLGWVEATPGRNGGLRLNIEPASLLLGDILQTLEGHPALVDCEKPACALKGNCNLKRILDLGLRDFFAAMNQYSLADLTQSPTSDVIARMHFQPRSLSARPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GU59</accession>
    <name>A0A2S9GU59_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="12">ABC-type multidrug transport system ATPase and permease component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">S2091_4033</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000026">
        <property type="protein sequence ID" value="PRC91248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91248">
        <property type="protein sequence ID" value="PRC91248"/>
        <property type="gene ID" value="S2091_4033"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="PTHR24221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="SSF90123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-1278">Translocase</keyword>
    <keyword evidence="2 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="183"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="225"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="299"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="330"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="411"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="443"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="11">
        <location>
            <begin position="186"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="508"/>
            <end position="741"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="540"/>
            <end position="547"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PRC91248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="756" mass="83977" checksum="A3FF270054140D2E" modified="2018-07-18" version="1">MTMKQVTDDLTLNNLPANWRDIVANQLTEGENALTALEVDLDAQLNFRKGIIVATGSRLLALAPDATEWQSWAYRADLVLKHHDHAGIGHLELVDTHGLLATWRFTLTQNLLATRLADQFKLYQTSQVSGLPIVEADQLVCPSCKAPLEPDQDECPICAKVIHTPPSTRTLFRLWRFAKPYQWPLFAGFVLTLLGTAAGLVPPYLTGPILDNVLIPYQETKHIDPTMVSLYLGGLLGSALLAWLLNWLRTYILALVSERIGSDLRTATYEHLMRLSLEYFGGKRTGDLMSRIGSGTDRICVFLSLHLLDFATDVIMLVMIAVFLVKQNPMLALVTLAPLPFIAWMIHIVRDRLRNGFEKIDRVWGEVTNVLADTIPGIRVVKAFAQEQREANRFHDANKHNLMVNDRLNKVWALFSPTVSLLTDIGMLVVWAFGIWQISKGEITVGVLVSFVALMGRFYGRLDSMSRIVSVTQKSASAAKRVFDILDHVSSVPEPTHPVKIAQVQGHIELREVGFRYGNRAVNRGISINIKPGEMIGLVGHSGSGKSTLVNLICRFYDVAEGAILLDGVDIRSFAVADYRRNIGLVLQEPFLFFGTIADNIAYGKPSATRDEIMDAARAAHAHEFILRLPQGYDSMVGERGQGLSGGERQRISIARALLIDPRILILDEATSSVDSETEKEIQKALDNLVKGRTTIAIAHRLSTLNKADRLVVMDRGVVVEEGKHDVLMAQQGAYYRLYQAQARNAAVLLESNEEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GU77</accession>
    <name>A0A2S9GU77_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3958</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000025">
        <property type="protein sequence ID" value="PRC91287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91287">
        <property type="protein sequence ID" value="PRC91287"/>
        <property type="gene ID" value="S2091_3958"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004343">
        <property type="term" value="F:glucosamine 6-phosphate N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006048">
        <property type="term" value="P:UDP-N-acetylglucosamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039143">
        <property type="entry name" value="GNPNAT1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13355">
        <property type="entry name" value="PTHR13355"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13673">
        <property type="entry name" value="Acetyltransf_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="5"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="141" mass="15762" checksum="4F24E0C79594B524" modified="2018-07-18" version="1">MTINITINNWAVQKEAARHVRMNVFVIEQQVPIELEWDTMDEQCIHAVATDETGAAVGTGRLLPDGHIGRMAVLATARGQGVGGQILMCLICEAQERGDKRVVLSAQRQAEGFYERFGFKVVGEEYMEAGINHIDMEFHFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUE4</accession>
    <name>A0A2S9GUE4_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">50S ribosomal protein L3 glutamine methyltransferase</fullName>
            <shortName evidence="4">L3 MTase</shortName>
            <ecNumber evidence="4">2.1.1.298</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">N5-glutamine methyltransferase PrmB</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">prmB</name>
        <name evidence="6" type="ORF">S2091_3994</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>L-glutaminyl-[ribosomal protein uL3] + S-adenosyl-L-methionine = H(+) + N(5)-methyl-L-glutaminyl-[ribosomal protein uL3] + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:45020"/>
            <dbReference type="Rhea" id="RHEA-COMP:11063"/>
            <dbReference type="Rhea" id="RHEA-COMP:11064"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30011"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:61891"/>
            <dbReference type="EC" id="2.1.1.298"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.298" evidence="4"/>
    <dbReference type="EMBL" id="PUGF01000025">
        <property type="protein sequence ID" value="PRC91323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91323">
        <property type="protein sequence ID" value="PRC91323"/>
        <property type="gene ID" value="S2091_3994"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036009">
        <property type="term" value="F:protein-glutamine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009007">
        <property type="term" value="F:site-specific DNA-methyltransferase (adenine-specific) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018364">
        <property type="term" value="P:peptidyl-glutamine methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02125">
        <property type="entry name" value="L3_methyltr_PrmB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004556">
        <property type="entry name" value="HemK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017127">
        <property type="entry name" value="Ribosome_L3_Gln-N5_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007848">
        <property type="entry name" value="Small_mtfrase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05175">
        <property type="entry name" value="MTS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037167">
        <property type="entry name" value="Mtase_YfcB_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00536">
        <property type="entry name" value="hemK_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03533">
        <property type="entry name" value="L3_gln_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4 6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 4 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="MTS" evidence="5">
        <location>
            <begin position="135"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF05175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC91323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="299" mass="33012" checksum="2D148B68BDC7F647" modified="2018-07-18" version="1">MSNLILTNHPFTTVRDVLRYAVSRFNGAKLFFGHGSSSAIDEAAYLILHTLHLPLDNLDTYLDAHLLPAEIAGILKVIERRTTDRVPAAYITNEAWLGTYQFYVDERVIVPRSFIAELIPSYLSPWVANPDDITDILELCTGSGCLPIMLADAFPEAHVDTADISTDALAVAKQNIATYGLQDRITLRESDLYTNVPNKKYQLIISNPPYVNSASMDKLPQEYLHEPQIALGGGEDGMDLVRTIIAGAKSRLTQNGILMVEIGHERAFAEAAFPDLEFTWVSTSAGDDMVFLLTADQLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUF7</accession>
    <name>A0A2S9GUF7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3889</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000024">
        <property type="protein sequence ID" value="PRC91344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91344">
        <property type="protein sequence ID" value="PRC91344"/>
        <property type="gene ID" value="S2091_3889"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="212" mass="23953" checksum="7E119E190CFEC7B6" modified="2018-07-18" version="1">MKHLSPQPVIVESHTTQKQDLRNEIATIAARFIAEDGATYAIAKQKAAQQVLGSSKINHDSLPDNSLIEQQVRLYNQLFFADSQPARLLYLRKLALTLLQELEQFNPHLTGAVLNGTAGEHSEIFIQLFVDNNKEVAIYLLNQRIQFEVSETLQGHQSRQQEAQETLSFMRANEVIHLVLFASDDVRRLSTKKMPRANASALQHLIEESLPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUG0</accession>
    <name>A0A2S9GUG0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">TonB C terminal</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3894</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000024">
        <property type="protein sequence ID" value="PRC91349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91349">
        <property type="protein sequence ID" value="PRC91349"/>
        <property type="gene ID" value="S2091_3894"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="65"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="292" mass="32430" checksum="078E1C70BBF5572A" modified="2018-07-18" version="1">MQNPTFTIAIIASLLAHAVLLLIHFVDPPPLPPVATDPGLDVILVNAKHDHAPLKAQALAQANLDGGGNADDGRAKSPIPDMHTSEDGDAIRKTQRRIEELENLQDHLLSQADKASFKVPTVLDKTKTDAPKPVISGDDQSESHKALTRMQAEIAQTIEDQNKRPRKTFITPSTKAVGYAMYYKNMQKRIEDMGTMQFPEKNGEKLYGELIVYIPIFQDGTIYEKEGGPRIEKSSGNKALDKAALRIVRHAGPFGTFPQNMRSSDKDDLWIVITRFKFTHDLDLITELKDAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUJ6</accession>
    <name>A0A2S9GUJ6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SWIB/MDM2 domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3929</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000024">
        <property type="protein sequence ID" value="PRC91384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91384">
        <property type="protein sequence ID" value="PRC91384"/>
        <property type="gene ID" value="S2091_3929"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.245.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019835">
        <property type="entry name" value="SWIB_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036885">
        <property type="entry name" value="SWIB_MDM2_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003121">
        <property type="entry name" value="SWIB_MDM2_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02201">
        <property type="entry name" value="SWIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00151">
        <property type="entry name" value="SWIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47592">
        <property type="entry name" value="SSF47592"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51925">
        <property type="entry name" value="SWIB_MDM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SWIB/MDM2" evidence="1">
        <location>
            <begin position="48"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="125" mass="13172" checksum="24633EA1E176F9CA" modified="2018-07-18" version="1">MATAKKPAAAVKKPAAAVKKPAAVKAAPAKAVKAVAAKVPAVKKANTAFMKPMTLSPTLAAVIGAAPIPRTEVTKKIWEYIKKHQLQDEANKRMINGDAKLVAVFGGKKQVSMFEMTKLISAHLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUN3</accession>
    <name>A0A2S9GUN3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3826</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000023">
        <property type="protein sequence ID" value="PRC91411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91411">
        <property type="protein sequence ID" value="PRC91411"/>
        <property type="gene ID" value="S2091_3826"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="68" mass="7784" checksum="BBFF75FC4F6D5AD7" modified="2018-07-18" version="1">MKYDLKNLNSESILLILDAPFYKLLTLKRSTDSTMITQIYFPYFVCAEAMQAAFDGPAKPSHFSISTW</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUP7</accession>
    <name>A0A2S9GUP7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Collagen triple helix repeat (20 copies)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3872</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000023">
        <property type="protein sequence ID" value="PRC91457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91457">
        <property type="protein sequence ID" value="PRC91457"/>
        <property type="gene ID" value="S2091_3872"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0176">Collagen</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015708628" evidence="2">
        <location>
            <begin position="21"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="59" mass="5534" checksum="F115D7BAE52BA16D" modified="2018-07-18" version="1">MKFSTSIATIAILVAISACSGPRGPQGNTGNTGNTGNTGATGATGAAGTSTTTTIVPAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUR7</accession>
    <name>A0A2S9GUR7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">UDP-N-acetyl-D-glucosamine 2-epimerase, UDP-hydrolysing</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3755</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000022">
        <property type="protein sequence ID" value="PRC91477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91477">
        <property type="protein sequence ID" value="PRC91477"/>
        <property type="gene ID" value="S2091_3755"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008761">
        <property type="term" value="F:UDP-N-acetylglucosamine 2-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006047">
        <property type="term" value="P:UDP-N-acetylglucosamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020004">
        <property type="entry name" value="UDP-GlcNAc_Epase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003331">
        <property type="entry name" value="UDP_GlcNAc_Epimerase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029767">
        <property type="entry name" value="WecB-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43174">
        <property type="entry name" value="PTHR43174"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02350">
        <property type="entry name" value="Epimerase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03568">
        <property type="entry name" value="NeuC_NnaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase_2" evidence="1">
        <location>
            <begin position="24"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="394" mass="43495" checksum="DF1BB3DEF87064F4" modified="2018-07-18" version="1">MKKILALTSIRSDYDLMSGLYELLNADPEIDLQLLVSGAHLSATFGTTVELIKKDGFKILIEIESLINADTQKSRLKTASILLQNAIDVVAGWQPDLILFAGDREDVLVGAMLGVFLAIPTVHFFGGDHEKDGHADTAVRHATSKLATFHVVSIEQHKQRLMKMGESAQRIAVVGSIALDKFVQLSSKKPIQPSTIFPPDKSLNNYALVIYHPIAEGRYDTMRAGIIFSTILSTLKKMGIPAIVSYPNSDPGNHLIIEQILKHETDPDFWFYKNLERDVFLSLFKQAQFLIGNSSSGILEAASLPLSVINVGERQKGRYCGNNVVFCGNEASEIEQAVNLVMTPDFQASMMKGRNPYGDGNSCKTAYALIKSTDFNQILKKTEDPLELAHLEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUV5</accession>
    <name>A0A2S9GUV5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">RimK-like ATP-grasp domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3777</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000022">
        <property type="protein sequence ID" value="PRC91499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91499">
        <property type="protein sequence ID" value="PRC91499"/>
        <property type="gene ID" value="S2091_3777"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-grasp" evidence="2">
        <location>
            <begin position="189"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="414" mass="46066" checksum="81DFE23F58A9AC49" modified="2018-07-18" version="1">MLNDTVVDAASQEKFKLIGLPTLMTLAFNGGDLAAIGEQLLARIKSDSHDANALMDMAVLFIMRGETKLARSMQTLAIQTKQVFHFPRPALPVKIRALAILGPGDLMANSPFEFLIEDQPIALDMLYITPSLSLPEIIPEHDVLIVAIGESDRNQPLLSYLDTTLNQWPRPVINQPCRISQLSRDAACAQLMNSTDIVMPPAMRITRDALEQCCRPEEFACTLTSQLNGVDYPIIIRPIDSHAGLGLNKIESLSALTGYLVDAPENIFFVSPFIDYRSADGLFRKYRLILINGVAYACHMAISSRWMVHYLNADMLENAGHRAEEAQFMENFNTDFAVRHASAIQAIYTQLGLDYVGIDCAETPDGKLLIFEVDSNMVVHNMDSAEKFPYKKIQMPKLFNAFAQLLAQRCGIIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUY7</accession>
    <name>A0A2S9GUY7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Serine/threonine protein phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3881</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000023">
        <property type="protein sequence ID" value="PRC91466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91466">
        <property type="protein sequence ID" value="PRC91466"/>
        <property type="gene ID" value="S2091_3881"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006470">
        <property type="term" value="P:protein dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00143">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015655">
        <property type="entry name" value="PP2C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832">
        <property type="entry name" value="PTHR13832"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00331">
        <property type="entry name" value="PP2C_SIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="SSF81606"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="2">
        <location>
            <begin position="5"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="266" mass="29209" checksum="1E04812FA1029C45" modified="2018-07-18" version="1">MSQYKIEAGTGQHVGDRKEQQDRTALFAAPKAPGYMMAVLADGMGGKSGGALAAEQVIRTAKQLFEEFGPDDDVKAAIEAIVRESHTIIQLSGISAEKEPHSTIVILIITPHHHAVWAHIGDSRLYRFSGANLIERTIDHSYVEKLVSEKKITSEEAKSHTLSNILVNVLGSSSTEPFITFNEYDGLKPTDSFLLCSDGLWHYFTDRELGAVISANTPRIASEMLINKARERASGRGDNCTMAIVKLIKPAKVEKGYTVEKMRRAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GV71</accession>
    <name>A0A2S9GV71_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Antibiotic biosynthesis monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3741</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000021">
        <property type="protein sequence ID" value="PRC91625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91625">
        <property type="protein sequence ID" value="PRC91625"/>
        <property type="gene ID" value="S2091_3741"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007138">
        <property type="entry name" value="ABM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025444">
        <property type="entry name" value="Monooxy_af470"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13826">
        <property type="entry name" value="DUF4188"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51725">
        <property type="entry name" value="ABM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABM" evidence="1">
        <location>
            <begin position="1"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="112" mass="13161" checksum="E8D821D12505B42F" modified="2018-07-18" version="1">MYIAAFIYKPSQIDQEFNRLSTIIGEIAHSIPGFIGAESWRSMDGLLVNASYYWRDQESLRAFATHPQHLDAKRQYRKWYEGYHVVVSKVERAYGDGSIKHFIQDSRQHHEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVT2</accession>
    <name>A0A2S9GVT2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Hydantoinase B/oxoprolinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_3563</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the oxoprolinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000019">
        <property type="protein sequence ID" value="PRC91808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91808">
        <property type="protein sequence ID" value="PRC91808"/>
        <property type="gene ID" value="S2091_3563"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008040">
        <property type="entry name" value="Hydant_A_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002821">
        <property type="entry name" value="Hydantoinase_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003692">
        <property type="entry name" value="Hydantoinase_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045079">
        <property type="entry name" value="Oxoprolinase_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11365">
        <property type="entry name" value="PTHR11365"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05378">
        <property type="entry name" value="Hydant_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01968">
        <property type="entry name" value="Hydantoinase_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02538">
        <property type="entry name" value="Hydantoinase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hydant_A_N" evidence="4">
        <location>
            <begin position="16"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="domain" description="Hydantoinase_A" evidence="2">
        <location>
            <begin position="214"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="domain" description="Hydantoinase_B" evidence="3">
        <location>
            <begin position="702"/>
            <end position="1208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF05378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC91808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="1222" mass="131357" checksum="C905C77BADDF57DB" modified="2018-07-18" version="1">MMDKSNDQTSSDKWQFWVDRGGTFTDIVAKKPDGSLATHKLLSEDPAHYRDAALAGIRALLGIERDQAIPAGVIDVVKMGTTVATNALLERKGERCALVVTRGFADALKIAYQNRPRLFDRHIVLPDQLAEIVIEADERINAQGEVLKPLQTEALRAELQTVFASGIRCVAIVLMHGYRYTQHEKQIQLIAREIGFSQISVSHIVSPMIKLVGRGDTTVADAYLSPILRRYVDQVASELGDTRLMFMQSNGGLTDAHLFQGKDSILSGPAGGIVGAVRTSELAGFTKIIGFDMGGTSTDVSHYNGELERVFESTVAGVRLRVPMMNIHTVAAGGGSILEFDGTRFRVGPASAGANPGPASYRKGGPLTVTDCNVMLGKIQPEFFPKVFGAEGNQRLGSDVVRQKFNALASEIAAAGLGQRTAEQVAEGFLQVAIENMANAIKKVSVQRGYDVSNYALCCFGGAGGQHACQVADALGMSRVVLHPFAGVLSAFGMGLANQRALRESSVERPLNVDNLSLVEASLTALATTAEQELLTQGIAQSAISTLRRVHLRYKGTDSAMVVNLAGIDVMRDQFEAQHQARYGFIMVGRELIVEAVSVEAMAEADDVLADNAFQARAGQQAAVPEAMVNMVSQQEEFATPVYLRANLSTIDHIQGPAIISDAVSTTVVEPGWAAHITQRNDLILERVTARPSRKAAGTEVDPVLLEVFNNLFMSIAEQMGATLENTSHSVNIKERLDFSCAIFDVNGNLIANAPHIPVHLGSMSDSIKSIIANNLGTMQPGDVYCLNAPYSGGTHLPDITVITPVFDEHKKQVLFYLGSRGHHADIGGITPGSMPPNSTHVDQEGILIDNFLLVEAGHFREAETRALLASGSWPARNPDQNIADLRAQIAANEKGEQELKQMLQQYGKDVVAAYMQHVQNNAEEAVRRVLVGLKDGDFSYAMDNGAVIKVSIRINREQRSAVIDFTGTSDQLPNNFNAPASISRSAVLYVFRTLVDAEIPLNEGCLKPLNIIIPEGSMLNPRYPAAVVSGNVETSQYVTDALYGALQVMGAAQGTMNNFTFGNEQYQYYETIAGGSGAGPGFNGASAVQTHMTNSRLTDPEVLELRFPVMVDEFSIRKGSGGVGQTTGGDGVIRKIRFKEAMTAAILSGHRIVAPYGAAGGQAAQLGLNYVLRASGERQLLTSTEETQMHVDDVFVVETPGGGGFGNANKRNNVKCGTETE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVT3</accession>
    <name>A0A2S9GVT3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Flagellar hook-associated protein 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3376</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000018">
        <property type="protein sequence ID" value="PRC91820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91820">
        <property type="protein sequence ID" value="PRC91820"/>
        <property type="gene ID" value="S2091_3376"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009424">
        <property type="term" value="C:bacterial-type flagellum hook"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071973">
        <property type="term" value="P:bacterial-type flagellum-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013384">
        <property type="entry name" value="Flagell_FlgL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001492">
        <property type="entry name" value="Flagellin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001029">
        <property type="entry name" value="Flagellin_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42792">
        <property type="entry name" value="PTHR42792"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00669">
        <property type="entry name" value="Flagellin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02550">
        <property type="entry name" value="flagell_flgL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0966">Cell projection</keyword>
    <keyword evidence="3" id="KW-0969">Cilium</keyword>
    <keyword evidence="3" id="KW-0282">Flagellum</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flagellin_N" evidence="2">
        <location>
            <begin position="3"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="407" mass="41894" checksum="1288C852C255DF87" modified="2018-07-18" version="1">MRISTSSLYQNAVTNFNNMQAAIATSINEVDSGISLTSPSVDPAAAAQVLVAGQASAVNTQFGVNRQNATNALSTSDGVLSGVTNMMQSLESLVVEAGNGSLAPSDRATVAQQFQSGISQLMNLANSTDSNGNYMFSGSTSGVQPYTVTSNGGQYNGNQETQMLQVDSSQQLPVTVVGSSIFGNIQVSPNAYFGIPNAANVSTATISSGTVTNAALVTDDNYSVTFTSPTAYNVTDTSTGAAISTNNVYTSGAPITIGGVQFNVTNGAGPTGVPVAGDQFAVQPGNQNIFQALTNIMTALNKPTVTAADQTNLANSVAQANTSISASLNNVLDVRDQLGNSMQQITSLNSVGTTVDLAYQTTISNLQDANYAQVISQLSEEQFTYQAAQKAFAATSQLSLISMLPVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVV1</accession>
    <name>A0A2S9GVV1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Sulfate permease and related transporters (MFS superfamily)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_3411</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Membrane</location>
            <topology evidence="1 5">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000018">
        <property type="protein sequence ID" value="PRC91855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91855">
        <property type="protein sequence ID" value="PRC91855"/>
        <property type="gene ID" value="S2091_3411"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008271">
        <property type="term" value="F:secondary active sulfate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011547">
        <property type="entry name" value="SLC26A/SulP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001902">
        <property type="entry name" value="SLC26A/SulP_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11814">
        <property type="entry name" value="PTHR11814"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01740">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00916">
        <property type="entry name" value="Sulfate_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SSF52091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50801">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="46"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="97"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="131"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="174"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="199"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="245"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="318"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="348"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="376"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="domain" description="STAS" evidence="6">
        <location>
            <begin position="432"/>
            <end position="544"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC91855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="553" mass="58851" checksum="58700DAFDA081E1C" modified="2018-07-18" version="1">MLSSLFPKTSNIHFYLKPIDVLAGLSVASLLLPQAVAYAFIAHMSIQAAIGASLVGLLLYAIFGASRFAIVSPTSSSAALVAAGALSLMPSGSEEQAALSFALVILTGCGLIIVAFARLGRLSAFVSRPVLRGFSFALAATIIIKQFPIMVGTHATGANPFTLLADLFEKMPQWSWWSLAAGTAALLLLISLKRYTKLPAAFIVLALGIGLAYACDLSVFQIAIVGPFELAIPHFGLPKLSLHQWLSAGELAGGLLVIIFSESWGSIRTLALQHGNHVEPNRELFALGAANLASGLIQGMPVGAGFSACVANEAAGAQSKWAGIAAAICMLFLVVYGKPLIEHIPEPILAATVIGALLHSLNPQPIIALWRMNRDQYLTLAAIAAVLFFGILHGMIIAVALSIASAIRTFSQPAVRELAELDSTRNYIDCGHHPEAMPHKNILILRPEEPLFFASVDGVFDVIKALVKSRVNCRIIIVSLEESSDLDSSATESLIELSHNLAKLGITLLLARVKDPIRLLLLKTAPDSFQDKLFWSVADAADHAKQLLPTMPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GW00</accession>
    <name>A0A2S9GW00_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ABC-2 family transporter protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3455</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000018">
        <property type="protein sequence ID" value="PRC91899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91899">
        <property type="protein sequence ID" value="PRC91899"/>
        <property type="gene ID" value="S2091_3455"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="240"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="270"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="307"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="352"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="393" mass="42950" checksum="A4CA2D7A45503947" modified="2018-07-18" version="1">MTSFTRALQSELAHLWKNPWDLAMISWVPLLAVWLVWAIFSQAIPTHLPIAVLDLDHSSASRQLTRMLDATPGLSVIAEVTDPAAAQTLLRRAKVIAVVEIPDDWMKSIKQGQSRPVHALYNAQFANASGLVTRDIRTVVATFSAGVEITARNKRGESILAAQVNMEPLRAGLISLYNTALNYEQFLTVNLVPALLHIFAMTAAVWTVGRELRDGTAGHWMVATQVNSFRQMCAALCAKLLPGIVVLGLIGSGFFIFLLLFRGWQPTGSLAIGIAALWLMLILYSVLGALLVGLLRSLRIGLSAVGFITAPAFAFAGVAFPVMGMPALAQLWANILPFSHYIHLQTRLWQQAAPVLTILPTLFFMLLASSIILVVATFVTRKAFLQADCWGKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GW11</accession>
    <name>A0A2S9GW11_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative phosphoribosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3460</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000018">
        <property type="protein sequence ID" value="PRC91904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91904">
        <property type="protein sequence ID" value="PRC91904"/>
        <property type="gene ID" value="S2091_3460"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRibTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00156">
        <property type="entry name" value="Pribosyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pribosyltran" evidence="1">
        <location>
            <begin position="14"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="179" mass="19998" checksum="603D4BD99E6055A9" modified="2018-07-18" version="1">MSLSDTTDGHLWVSWDEYHRLIEKLALRVYESGWEFDQILCLARGGLRPGDVLSRIFNVPLAILSTSSYRAESGTQQGVLDIAKHITMTSGSLAGRVLVVDDLVDTGVTLQAVTAHLTEHFRAVTEVKSAVIWQKAASSIVPDYAIEYLVGNPWIHQPFEDYDGLRPDQLLMRVQKHHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GW94</accession>
    <name>A0A2S9GW94_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3326</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000017">
        <property type="protein sequence ID" value="PRC91984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91984">
        <property type="protein sequence ID" value="PRC91984"/>
        <property type="gene ID" value="S2091_3326"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010752">
        <property type="entry name" value="DUF1329"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07044">
        <property type="entry name" value="DUF1329"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015765172" evidence="1">
        <location>
            <begin position="25"/>
            <end position="459"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="459" mass="51532" checksum="0DA1C60E0C6BB0C4" modified="2018-07-18" version="1">MKIANVLRALAVTGLVTGLVTASAADMTRLGQDLTGVGAEKAGSKDGAIPEFSGMSKPLPGWSYGKLREDFWKYKAEKALFVIDASNVDKYADKLTAGQIQMLKQVKGYTMPVYPAHRECGLPDSVINSTKATAGKSAIGKNGWTLDSAVLPSVPFPMPQTGIEVMWNWLMRYQGLAAEWPDAYTVVSPRPGTTTPITTRWNQLSYFPWVDKPMSGNLEPEAMQNGFYYLYTEPAALAGQGTIQRYYYGKDVDTFYYFTGQRRVRRLPMYAYDAPLIGYENQYPADISFVFYGNPDRFDWKLVGKKDVYIPYNGFGMQRFNTKISEAMQANYVNPAMRRYELHRVWEVEGTVKSGVRHSTPKKTLYIDEDSWWVAVGDDFDAQGKIWKAKENNITPQWELGACASSASVYNDLISGRYVLDETIIGTGKDIRSYPPGSKDPRFKDNFFTAENLSAISDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWE9</accession>
    <name>A0A2S9GWE9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Prolyl oligopeptidase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_3179</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000016">
        <property type="protein sequence ID" value="PRC92044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92044">
        <property type="protein sequence ID" value="PRC92044"/>
        <property type="gene ID" value="S2091_3179"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015760329" evidence="2">
        <location>
            <begin position="33"/>
            <end position="859"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S9" evidence="3">
        <location>
            <begin position="682"/>
            <end position="844"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="213"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="214"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="231"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC92044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="859" mass="94329" checksum="2FDFDFCF1521CA39" modified="2018-07-18" version="1">MQSVWSVKRLPKSRAVLMSLSMLLLAPASSIATSMDAQPNAATASAALSGYNQPPKNILDVMHAPSPPTASVSPTQDMMLLVSMQDYPSISRVATPFLRLAGVRVESKNHSKHDTPGGYGITPCASSFELVRIADGKQTPVALPEGACPGVPIWAADGKHFAFINIAAEAVELWVGDGMTGAVHRVPGVRLNPMLNDELQWMADQKTLLVKLVPDGMPPPPPEPLIPSGPSIQETDGSKGQSSTYENRDTLGNKHDEDLFDYYATSQLALVDVSSSVITPIGKPGNYETVDLAPDGQHLLVSTIRKPYSYVTTYERFPKTIEVWSALTSEQISKQHIASNPLADRVPIHGVPVGPRAFSWRATDPASLIWAEALDGGDWNVKVPARDKVLMLKAPFTSPAVEITRTEQRYVGFIWSEQPSLAILTEYDNNRHWRRSFTINVDEKPAKPRLFWDMSTDEKYENPGMPVTRQLANGAWVMRQDGDAIYLSGAGASPDGDRPFLDRFNFKTHKVERLFRSDKTSYERFLSFNGSDTQTFLTWSQSITDTPNAFARTLGKAITAPKGEAAYASTSVAITHIPDPTPEVREIKKRLVKYKRADGLDLSFTLYTPPGYKDGTRVPTILYAYPLDYADASKAGQVTGSQATFTRLRQYKLLLLAGYAIIDNAAFPIVGDPKKAYDTYMEQLVADAKAAVNEAVRLGVADPDRIGVTGHSHGALMTANLVTHSDLFRAGVATSGSYNKTLTPFGFQSEQRSVWEASDVYRKVSPFFYADKLKTPLLIVHGADDANPGTTPLQASKLYEAIRGNGGTTRLVMLPHEPHWYTAMESNEQLIYEMIRWFDKYVKNADVKNAASKPVAVTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWQ0</accession>
    <name>A0A2S9GWQ0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ABC-type multidrug transport system ATPase component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_3060</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92144">
        <property type="protein sequence ID" value="PRC92144"/>
        <property type="gene ID" value="S2091_3060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-1278">Translocase</keyword>
    <feature type="domain" description="ABC transporter" evidence="7">
        <location>
            <begin position="2"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="34"/>
            <end position="41"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC92144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="289" mass="32023" checksum="B3A1514E1659F4E6" modified="2018-07-18" version="1">MLELRHVVKRFGKNLVAVDDVSLNLTHGVVGLIGHNGAGKTTLMQMIATLTVPTSGQILLDGQDITKKPKLIRPRLGYLPQDFGIYPNLSALEFMQYFAALKGCNDPERIRYLLELVNLHEHAKRPAASFSGGMRRRLGIAQALINDPDILIVDEPTAGLDPAERMRFRNLLSELGFSKLVIMSTHIVSDVESIATQLAVMRSGKLLAFETPETILEQAQGQIWTAEIDSQYYEQLRSKVHVLNAQRLGNSMVVRIAHPHQPCFDAVLAEPSLEEALMAQQLTKQVALA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GX42</accession>
    <name>A0A2S9GX42_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7">Malate synthase</fullName>
            <ecNumber evidence="2 7">2.3.3.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_2939</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>acetyl-CoA + glyoxylate + H2O = (S)-malate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18181"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15589"/>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="EC" id="2.3.3.9"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Carbohydrate metabolism; glyoxylate cycle; (S)-malate from isocitrate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the malate synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.3.9" evidence="2 7"/>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92280">
        <property type="protein sequence ID" value="PRC92280"/>
        <property type="gene ID" value="S2091_2939"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00703">
        <property type="reaction ID" value="UER00720"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004474">
        <property type="term" value="F:malate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006097">
        <property type="term" value="P:glyoxylate cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00727">
        <property type="entry name" value="malate_synt_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1220.12">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044856">
        <property type="entry name" value="Malate_synth_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011076">
        <property type="entry name" value="Malate_synth_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006252">
        <property type="entry name" value="Malate_synthA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001465">
        <property type="entry name" value="Malate_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019830">
        <property type="entry name" value="Malate_synthase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046363">
        <property type="entry name" value="MS_N_TIM-barrel_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42902">
        <property type="entry name" value="PTHR42902"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01274">
        <property type="entry name" value="Malate_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001363">
        <property type="entry name" value="Malate_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51645">
        <property type="entry name" value="SSF51645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01344">
        <property type="entry name" value="malate_syn_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00510">
        <property type="entry name" value="MALATE_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0329">Glyoxylate bypass</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 7" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="164"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="6">
        <location>
            <position position="446"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR001363-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC92280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="528" mass="58765" checksum="9C7AB253F81A32FC" modified="2018-07-18" version="1">MTQLQLPAGMEIIGEIKPGFASILTPEALALIAKLTRTFEPRRQELLAARTARAARMDAGERPDFLPETAHIRAGDWKIAPIPKALECRRVEITGPVERKMVINALNSGADSYMTDFEDSNTPNWDNQVTGQLNMRDAVRKTISMEQNGKSYKLNETTATLVVRPRGWHLDEKHVLVDGRRISGGVFDFALFMVHNAKEQLARGAGPYFYLPKLESHLEARLWNDIFVMTQNELGLPQGTIKATVLIETILAAFEMDEILYELREHSSGLNAGRWDYIFSCIKKFKNDKDFCLADRAKVTMTAPFMRAYALLLLKTCHKRNAPAIGGMAALIPIKNDPEKNDIAMGGVRTDKARDATDGYDGGWVAHPGLVDLAMGEFKKVLGDKLNQIDKQRPDINVSAADLLNFQPETPITEAGLRYNINVGIHYLGAWLAGNGCVPIHNLMEDAATAEISRSQVWQWIRSTKGVLDDGRKVTDAMVRAMIPEELAKVKALVGDGATYDRAATIFEEMSTSDNFAEFLTLPLYEEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXH5</accession>
    <name>A0A2S9GXH5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Zn-dependent hydrolase including glyoxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2802</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92427">
        <property type="protein sequence ID" value="PRC92427"/>
        <property type="gene ID" value="S2091_2802"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050313">
        <property type="term" value="F:sulfur dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07724">
        <property type="entry name" value="POD-like_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044528">
        <property type="entry name" value="POD-like_MBL-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lactamase_B" evidence="1">
        <location>
            <begin position="22"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="295" mass="32608" checksum="60EFE58A35706DBB" modified="2018-07-18" version="1">MQQTIMTPLQPQIHPIYDEATATITYVVFDAPNGHAAIIDPVLNFQANSATTDTKSADLALAFIAQQGLTVDWILETHAHADHLSAAHYLQSKAGGKIAIGEHICQVQKVFKDLFNLEPEFAVDGSQFDHLFTENEIFKIGDLSAKALFVPGHTPADMAYQIGDVIFVGDTLFMPDVGTARCDFPGGDAHMLYQSIQKLLAFPENTRLFMCHDYPTADRSAQWESSVAQQRQYNIHVNETIDEATFVARRKARDATLSMPQLILTAIQINIRAGQLPTPENNGVSYLKIPLNAVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXK4</accession>
    <name>A0A2S9GXK4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">RimK-like ATPgrasp N-terminal domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2813</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92438">
        <property type="protein sequence ID" value="PRC92438"/>
        <property type="gene ID" value="S2091_2813"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013651">
        <property type="entry name" value="ATP-grasp_RimK-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025839">
        <property type="entry name" value="RLAN_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08443">
        <property type="entry name" value="RimK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14401">
        <property type="entry name" value="RLAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-grasp" evidence="2">
        <location>
            <begin position="333"/>
            <end position="526"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="547" mass="61733" checksum="75FC76E36BDD609D" modified="2018-07-18" version="1">MPKAKATTPPTRSFNLQQLLASDAELSSGSTMLNLARFSRKRTADFLIIVENNKDWIPRSDYEQVVSASDYLGSDAAYAKPGTIVINLCRSYKYLSIGYYCSLLAEARSQQVIPSVKTVNDLSHKAIYSLDMSDLDYALNGIFSKNANQPLPVEFAMDIFFGMTDYTPLAQLAQQLFDIFPAPLIRVEFEHRSDWKIRSVKVQNISSLCAYQKEIFIQAFDTFHGKAWLQNYAGKKHRYNIAILHNPEELLPPSNNAALAKFVQVGRELGIDVTLVEKKHYSHIAEYDALFIRETTAINHHTYRFAKKAESEGLVVIDDPVSILRCTNKIYLADLMRVNGIATPRTYVLQESDIDDITELEQEIAYPMVMKIPDGAFSRGVSKVVNRHEFESTARELLKHSSLILIQEYLYTEFDWRIGVLNKQVIFASQYFMSTGHWQVAKRDADGKAEFGMSRAVSLDKVPPDLLAQAVRAANLIGDSLYGVDMKMTEKGPVVIEVNDNPNIDQGIEDGVLGDELYRMILQDFVRRLRVQHQQVTSSMPEIGAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXL4</accession>
    <name>A0A2S9GXL4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2842</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92467">
        <property type="protein sequence ID" value="PRC92467"/>
        <property type="gene ID" value="S2091_2842"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="64" mass="7245" checksum="60A6180F429D5F89" modified="2018-07-18" version="1">MRLLISLILPWLTFFTIGRPIAGIICLLLQITLIGWIPATIWSVYALSQYTTDKKIEKALAQRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXQ5</accession>
    <name>A0A2S9GXQ5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2880</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92505">
        <property type="protein sequence ID" value="PRC92505"/>
        <property type="gene ID" value="S2091_2880"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="64"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="94"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="125"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="226" mass="25247" checksum="A9D8BBE44A23EF98" modified="2018-07-18" version="1">MQNSNDPLAVAEVYLSYGRKPQAEKVLEEAIRKEPDRIEFQNKLLEIRSGKTNNSRKKMSKSDVKVVMTFFGGMLLLIWSMVEGPRILNSTPLVETALLIGVTLAVLAALAAIRSRPDDSDRTNNTAKIFLFSVGIVAGTVGLTLVTNNHFPRSDPVPVSFLILDKSSRPSKHGLNYYLTIDDNGRSEKIQLQWRQWSKYSPGDHYSTNVGVGLWGYPTIPAIRDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXS0</accession>
    <name>A0A2S9GXS0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2831</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92456">
        <property type="protein sequence ID" value="PRC92456"/>
        <property type="gene ID" value="S2091_2831"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021738">
        <property type="entry name" value="DUF3309"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11752">
        <property type="entry name" value="DUF3309"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="30"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="52" mass="5495" checksum="4F6997E010A9F5AA" modified="2018-07-18" version="1">MSIGMILLIILVLALVGVIPSWPHSRGWGYGPSGGVGLILVIVLILFLLGRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GY17</accession>
    <name>A0A2S9GY17_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Holo-[acyl-carrier-protein] synthase</fullName>
            <shortName evidence="8">Holo-ACP synthase</shortName>
            <ecNumber evidence="8">2.7.8.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">4'-phosphopantetheinyl transferase AcpS</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">acpS</name>
        <name evidence="10" type="ORF">S2091_2667</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>apo-[ACP] + CoA = adenosine 3',5'-bisphosphate + H(+) + holo-[ACP]</text>
            <dbReference type="Rhea" id="RHEA:12068"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="Rhea" id="RHEA-COMP:9690"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:58343"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="EC" id="2.7.8.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the P-Pant transferase superfamily. AcpS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.7" evidence="8"/>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92612">
        <property type="protein sequence ID" value="PRC92612"/>
        <property type="gene ID" value="S2091_2667"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008897">
        <property type="term" value="F:holo-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.470.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00101">
        <property type="entry name" value="AcpS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008278">
        <property type="entry name" value="4-PPantetheinyl_Trfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037143">
        <property type="entry name" value="4-PPantetheinyl_Trfase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002582">
        <property type="entry name" value="ACPS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004568">
        <property type="entry name" value="Ppantetheine-prot_Trfase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01648">
        <property type="entry name" value="ACPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56214">
        <property type="entry name" value="SSF56214"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00516">
        <property type="entry name" value="acpS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00556">
        <property type="entry name" value="pantethn_trn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 8" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="4 8" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="1 8" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="6 8" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="5 8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ACPS" evidence="9">
        <location>
            <begin position="4"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="8"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="62"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC92612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="134" mass="14771" checksum="14AD7B58F1C96D3D" modified="2018-07-18" version="1">MVYGIGTDIVQISRIVATLARTGERFAEKILGAEEFLEYQQRHANVGVHGLHYLCNRYAAKEAFSKALGLGMRAPLSWHTIQILNDSNGAPYIVTSGDLAEHMQSMQLTAKISLSDEVDYSLAFVLIEKNNDAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GY48</accession>
    <name>A0A2S9GY48_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2694</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92639">
        <property type="protein sequence ID" value="PRC92639"/>
        <property type="gene ID" value="S2091_2694"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="65" mass="7098" checksum="682DE3BB3FC42ED9" modified="2018-07-18" version="1">MEINTEERDLIIALRILPKDIAGSIFRTAASQLKIYSSTEVGESSDRAAEVVTPPRRLRLVVGGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYF2</accession>
    <name>A0A2S9GYF2_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cytochrome bo(3) ubiquinol oxidase subunit 3</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Cytochrome o ubiquinol oxidase subunit 3</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">Oxidase bo(3) subunit 3</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="15">Ubiquinol oxidase polypeptide III</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Ubiquinol oxidase subunit 3</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">S2091_2485</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Heterooctamer of two A chains, two B chains, two C chains and two D chains.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="16">Cell membrane</location>
            <topology evidence="16">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 16">Belongs to the cytochrome c oxidase subunit 3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92755">
        <property type="protein sequence ID" value="PRC92755"/>
        <property type="gene ID" value="S2091_2485"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009486">
        <property type="term" value="F:cytochrome bo3 ubiquinol oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004129">
        <property type="term" value="F:cytochrome-c oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019646">
        <property type="term" value="P:aerobic electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02863">
        <property type="entry name" value="Ubiquinol_oxidase_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024791">
        <property type="entry name" value="Cyt_c/ubiquinol_Oxase_su3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000298">
        <property type="entry name" value="Cyt_c_oxidase-like_su3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035973">
        <property type="entry name" value="Cyt_c_oxidase_su3-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013833">
        <property type="entry name" value="Cyt_c_oxidase_su3_a-hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014206">
        <property type="entry name" value="Cyt_c_ubiqinol_oxidase_su3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033946">
        <property type="entry name" value="Ubiquinol_oxase_su3_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11403">
        <property type="entry name" value="PTHR11403"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00510">
        <property type="entry name" value="COX3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81452">
        <property type="entry name" value="SSF81452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02842">
        <property type="entry name" value="CyoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50253">
        <property type="entry name" value="COX3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0249">Electron transport</keyword>
    <keyword evidence="10 17" id="KW-0472">Membrane</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 16 17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 17" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="36"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="76"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="105"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="145"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="190"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="domain" description="COX3" evidence="18">
        <location>
            <begin position="29"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00025694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00030072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00031884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00032189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00032717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU003376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="PRC92755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="212" mass="23656" checksum="159A861B7D76BCB3" modified="2018-07-18" version="1">MSEITPSFAGASSGANPSSRFYVLEHHPENGTLLGFWLYLMSDCLVFACLFATYAVLGRNYAGGPTGAELFDLPLVALNTAFLLVSSITYGFAMLEMQRKKMRTTLIWLAITGILGACFLSLELYEFVHLIHEGAGPQRSGFLTSFFALVATHGLHVTFGIIWLITLMFQVGRHGFTTENNRRLMCLSMFWHFLDVVWIGVFTFVYLMGVLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYG8</accession>
    <name>A0A2S9GYG8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2470</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92740">
        <property type="protein sequence ID" value="PRC92740"/>
        <property type="gene ID" value="S2091_2470"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="23"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="83"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="244" mass="27775" checksum="4B517B885357EEBC" modified="2018-07-18" version="1">MFETLQSDLTRIALDRYIQHFEVLQYLGILSFSLVLMFYTKIGSISFKALFFILFLSVLDPIYWGILNALLEQSGRRQMPYGVLFGWGGFWVLGIALLILFSRYVIPMLSIGLSRISRSSSMERNKRTDVRNIQEFLPKSIDFDPARYINLKKGIFLGLNENRKPHFLNIPMETNAPHLQVIGTTGAYKGVALGLMGAQFLERGEAVFFFDPKNDEWAPHVLSSAAKRCGKQFYFINLNAPNGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYP2</accession>
    <name>A0A2S9GYP2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Amidohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2575</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92845">
        <property type="protein sequence ID" value="PRC92845"/>
        <property type="gene ID" value="S2091_2575"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="SSF51338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015684673" evidence="1">
        <location>
            <begin position="22"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="domain" description="Amidohydro-rel" evidence="2">
        <location>
            <begin position="324"/>
            <end position="658"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="711" mass="77081" checksum="C910EE9235159B4A" modified="2018-07-18" version="1">MKSKVMAIAMLSVMSAYAANAAETTRYTIILDNGTVAGKQIVDSNDKGDVKVHFTFKDNGRGPDLDENIHLAPDGTMSKYEVKGASTFGAVVDDHFTQTGSQAEWHSTSEHGSKKVDGPATSSAFYLPMNSSYEVASLGITALSKRKDNNLPLLPSGNLSQHKVDDMVVKLGGKSQHVQLLAQTGIGFNPQFYWATTGKSPRLFAAIAPGYATLIEDGWQSNTAELTKHQSLASDKLLKELATRTQHAMTGLTVIRNARVFDSETAQLGAASDVYVLRGKITQVLAAGSPVAGADNEIDAAGRVLLPGLFDMHGHVDRWSGGLNLAAGVTSVRDMGNSNAEMQKMIDEIAADQLLSPQLVPSGFLEGNSPYAAQMGFVIKDLKEAKHAVDWYSEHGYPQLKIYNSFPHEDVKEIVAYAHSHGMRVSGHVPVFMRAQEVVEQGFDEIQHINQVLLNFLVTPTTDTRTLDRFYLPAEKVADLDFDSKEVQDFIALLQAHHTVIDSTLSTFDFIKQRDGDMAEPYAAIADHMPPDVKRSFSVGQMKIPDDATAKRYLASYNKMVEFVGRMYRAGIPLVAGTDALSGFTLQSELELYVKAGLTPAQALQVATRNGARYTRTTNERGSITAGKLADLVLVDGDPTMNIGDIRKVALVITRGKLIYPHEIDKELGIQPFVQNPPMMKALAPTSSSIATSGVGGVAPQMGRFGMDAKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYQ0</accession>
    <name>A0A2S9GYQ0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2582</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92852">
        <property type="protein sequence ID" value="PRC92852"/>
        <property type="gene ID" value="S2091_2582"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021853">
        <property type="entry name" value="DUF3460"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11943">
        <property type="entry name" value="DUF3460"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="63" mass="7262" checksum="8594348FBDE3CEFC" modified="2018-07-18" version="1">MLFSKQKTRYQSEATLFIDGLKKANPQLEQNQLTGRALLWDKAPLSLDEQQRSLDSTITRDSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZ29</accession>
    <name>A0A2S9GZ29_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2409</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92992">
        <property type="protein sequence ID" value="PRC92992"/>
        <property type="gene ID" value="S2091_2409"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="30"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="66" mass="6949" checksum="E66C7181CF7DC004" modified="2018-07-18" version="1">MKWAGLYLVGFVILIGGVLAAFWKLGILASIGTAWTLIGVAIAFGIGIMIAISNSGSKENIEINRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZ32</accession>
    <name>A0A2S9GZ32_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Hemolysin activation/secretion protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_2398</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell outer membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the TPS (TC 1.B.20) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92981">
        <property type="protein sequence ID" value="PRC92981"/>
        <property type="gene ID" value="S2091_2398"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005565">
        <property type="entry name" value="Hemolysn_activator_HlyB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013686">
        <property type="entry name" value="Polypept-transport_assoc_ShlB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034746">
        <property type="entry name" value="POTRA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08479">
        <property type="entry name" value="POTRA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03865">
        <property type="entry name" value="ShlB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51779">
        <property type="entry name" value="POTRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015692824" evidence="7">
        <location>
            <begin position="27"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="domain" description="POTRA" evidence="8">
        <location>
            <begin position="75"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC92981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="567" mass="60871" checksum="6AB01F2FEF54059C" modified="2018-07-18" version="1">MKTKNFTHSLHAIVIAMAFSTGAALAQTVPNIGDALRQAQPPAVPNPPAPALPQINGTQLQIEAPMTALPNAPQVTVNKLEIVGNRVIDTATLNGLVADGTGKSLTLAELEGLAQRITRHYRAKGYFVARAYIPAQEVANGTIKIRVVEGNYGQFRLKNQSLVKDDIVQNMLDDVKHYDIVSLETLERAMLIINDTPGVQVTRADVMPGEKVGTSDFAIDTKATERYTGFVMLDNFGSIYTGRDRLSFNVDDNSISGHGDRLSISGLGTDAGGLLNGRVGYLLPLAANGLRGELAYSQTKYQLGSTYEALDATGTAKGVDATLSYPVIRTHAQTVEVNFNLSHKNLEDNIQSTNTVTPKTTTSATAGVLVKDERKLLSFDGLTQASAKITFGHLDINNADALAADNAGARTEGNYSKLDAEVSRVSILPESLTFTTSLKVQQTLDNKNLDSSEQMAVSGSGGVMAFPSGELIGSNAVFVHVELSRPLPPVGELQSNWQIFTEWGTAKEPNPLSTDISRHISDVGLGWSASYKGALIHAYLAHRVDSTPAVSEPYPDYKFLLQAGWVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZB4</accession>
    <name>A0A2S9GZB4_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF5906 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2161</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93075">
        <property type="protein sequence ID" value="PRC93075"/>
        <property type="gene ID" value="S2091_2161"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01029">
        <property type="entry name" value="TOPRIM_primases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045455">
        <property type="entry name" value="DUF5906"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025662">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034154">
        <property type="entry name" value="TOPRIM_DnaG/twinkle"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19263">
        <property type="entry name" value="DUF5906"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00675">
        <property type="entry name" value="SIGMA54_INTERACT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF5906" evidence="2">
        <location>
            <begin position="540"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="340"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="356"/>
            <end position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF19263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="830" mass="92588" checksum="CDA284DA1A13B947" modified="2018-07-18" version="1">MSRDDFQHVKQAALYSIEALLTRWLPNGVLEGREWCIGSREGEAGRSMKVCIAGERIGRWSDFASGDTGGDLISLYSYINSISQLVAMKEVAGQLGIDIASARIKSAITPIKTSVSAIPELIKNKRTAWVPILPVPDDAPVAPVAHLVRGRSEISWAYRNQQGYLLGMVHRFKTSKVGKDGKPGKEFYPCVYARHPNTGASEWRWMGFPDPRPLYLTAPLRDDALVLIPEGEKCADAGFKAFPQLDVVSWGGGSNAVAKHDWTPLAGRNVIVWSDADAAGAKATLKLIAILFAIGCTVKIVLIPDGVEEGWDIVNAIEDGRDVRAMLSAAVLVTASDLTALGETGSPPSPTGEEQRLGDESPKDEHQKNHTTRKLSLVVSNKPDIPAPDAVQPGEGKAKRKLVERGESFWDGVNHLLEHFTLLYGTNTAWDDVERIQILIPNLRYAFGADQVKFWLNNRDRKMINSRCLVFDPTETVDLETHVNMFNGFNLEPQAGECGLILDLLAHLCGDQQELIDWVIKWIAYPLQHPGAKMSTSIIMHGDEGSGKNLFWETVVRNLYGEYGGVIGNAQLEAQFNEWASKKLFFVADEVVTRNELRQMKGKLKSLISGDEININPKNLPERREANHINFVFLSNELQPLALDKTDRRYLVVWTPPKHEAEYYKAIADQVGSGGLEAFYHYLLQVDCSDFNAHTKPIDTVAKRNLISLGLTSPERFYREWEAGVLPLPFISCSAMQLFAAFLRWSNLNNERFPPTQTEFGGKVERMAAGAVKRKAVKYDLRNVVKQRIVYLVGTPPEGKKLNEWVGDASDLFETYLKKYRHVYDQSEQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZD9</accession>
    <name>A0A2S9GZD9_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF4376 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2188</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93102">
        <property type="protein sequence ID" value="PRC93102"/>
        <property type="gene ID" value="S2091_2188"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025484">
        <property type="entry name" value="DUF4376"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14301">
        <property type="entry name" value="DUF4376"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4376" evidence="2">
        <location>
            <begin position="93"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="162"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14301"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="198" mass="22450" checksum="F32625A100CE6EA7" modified="2018-07-18" version="1">MINYVMHDSKTGEIIQWGTCSDGQMHEYKRDGVDVVEGDGNPDTHFVENGLIHLYSDIELSLKNNVPEGFIWKMPERILVDQRDLSMVKEQAWNRIKNERNLAESANFICNGAVYQADKERIPLAMQTALQAKLDGTVFTIDWVLADNSTITLTASDMINVGTALNKQMAEVNEKSQRLRQEIHQATSIAEIDLINWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZE1</accession>
    <name>A0A2S9GZE1_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 6">Lysozyme</fullName>
            <ecNumber evidence="2 6">3.2.1.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_2191</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>Hydrolysis of (1-&gt;4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins.</text>
            <dbReference type="EC" id="3.2.1.17"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the glycosyl hydrolase 24 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.17" evidence="2 6"/>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93105">
        <property type="protein sequence ID" value="PRC93105"/>
        <property type="gene ID" value="S2091_2191"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003796">
        <property type="term" value="F:lysozyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016998">
        <property type="term" value="P:cell wall macromolecule catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019835">
        <property type="term" value="P:cytolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042742">
        <property type="term" value="P:defense response to bacterium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009253">
        <property type="term" value="P:peptidoglycan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.530.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_04110">
        <property type="entry name" value="ENDOLYSIN_T4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034690">
        <property type="entry name" value="Endolysin_T4_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002196">
        <property type="entry name" value="Glyco_hydro_24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023346">
        <property type="entry name" value="Lysozyme-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023347">
        <property type="entry name" value="Lysozyme_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00959">
        <property type="entry name" value="Phage_lysozyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53955">
        <property type="entry name" value="SSF53955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0929">Antimicrobial</keyword>
    <keyword evidence="4 6" id="KW-0081">Bacteriolytic enzyme</keyword>
    <keyword evidence="6" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003788"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC93105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="157" mass="17581" checksum="A9A49EF4E5FC172E" modified="2018-07-18" version="1">MNLKNRIYIGIITAVMTAGFVQWESSGKVITQPYFDLAGIPTVCDGHTGNVDINRIYTPQECTDFRNQDIVKHLNGMLECVEVPLKQHQVNAFTLFASNVGVNAFCNSKNTVVGPLNRGDYAAACDGLRRWVYVGKQRVQGLVNRREFERKLCLGEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZE4</accession>
    <name>A0A2S9GZE4_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Site-specific DNA-methyltransferase (adenine-specific)</fullName>
            <ecNumber evidence="3">2.1.1.72</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_2195</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 2'-deoxyadenosine in DNA + S-adenosyl-L-methionine = an N(6)-methyl-2'-deoxyadenosine in DNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:15197"/>
            <dbReference type="Rhea" id="RHEA-COMP:12418"/>
            <dbReference type="Rhea" id="RHEA-COMP:12419"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:90615"/>
            <dbReference type="ChEBI" id="CHEBI:90616"/>
            <dbReference type="EC" id="2.1.1.72"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the N(4)/N(6)-methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.72" evidence="3"/>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93109">
        <property type="protein sequence ID" value="PRC93109"/>
        <property type="gene ID" value="S2091_2195"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009007">
        <property type="term" value="F:site-specific DNA-methyltransferase (adenine-specific) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1020.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023095">
        <property type="entry name" value="Ade_MeTrfase_dom_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012263">
        <property type="entry name" value="M_m6A_EcoRV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012327">
        <property type="entry name" value="MeTrfase_D12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30481">
        <property type="entry name" value="PTHR30481"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02086">
        <property type="entry name" value="MethyltransfD12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000398">
        <property type="entry name" value="M_m6A_EcoRV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00505">
        <property type="entry name" value="D12N6MTFRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5 7" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC93109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="326" mass="37133" checksum="90AD25A42FF49CE4" modified="2018-07-18" version="1">MAQNKTPLRYPGGKQKLTPFVLEIIRANGLEGGHYVEPYAGGAGVAMELLVAGHVNQIHLNDSSLPIYALWNSILTHTEEFCRRISRALLNVEEWKDYREIMRNPNDHSELDVGFATFYLNRTNRSGVLSAGVIGGLDQAGKWKIDARFPRNELIRRIELIGGFRDSITLLNLDAEQIITDYIPTLPENTLTYCDPPYFEKASKLYLNHYAPNDHERIAGIIQQQRDKKWIVSYDGVAQILGYYANRRKFLYELQYNAARAYKGNEVFIFSDNLVVPRNSVLPHIAVALKANTRKLHQPAEIARLITRAARLDNLRQTNKNLSRAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZF2</accession>
    <name>A0A2S9GZF2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phage gp6-like head-tail connector protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2169</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93083">
        <property type="protein sequence ID" value="PRC93083"/>
        <property type="gene ID" value="S2091_2169"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08054">
        <property type="entry name" value="gp6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021146">
        <property type="entry name" value="Phafe_gp6_head-tail"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05135">
        <property type="entry name" value="Phage_connect_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="113" mass="12596" checksum="0057A37D7E060693" modified="2018-07-18" version="1">MFVTLKLVKQNSSIDSSDTDEFLEFLINSAGQEAEEYLNRKLFINEVAMAQAVQDNKAGACPLVIVAPIQHAILIMIDEAYKNRGETVTGVSITSLPYGTRKRLDRYRIFAGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZQ3</accession>
    <name>A0A2S9GZQ3_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Lipoyl synthase</fullName>
            <ecNumber evidence="6">2.8.1.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Lip-syn</fullName>
            <shortName evidence="6">LS</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Lipoate synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Lipoic acid synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Sulfur insertion protein LipA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">lipA</name>
        <name evidence="9" type="ORF">S2091_1953</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>[[Fe-S] cluster scaffold protein carrying a second [4Fe-4S](2+) cluster] + 4 H(+) + N(6)-octanoyl-L-lysyl-[protein] + 2 oxidized [2Fe-2S]-[ferredoxin] + 2 S-adenosyl-L-methionine = (R)-N(6)-dihydrolipoyl-L-lysyl-[protein] + 2 5'-deoxyadenosine + [[Fe-S] cluster scaffold protein] + 4 Fe(3+) + 2 hydrogen sulfide + 2 L-methionine + 2 reduced [2Fe-2S]-[ferredoxin]</text>
            <dbReference type="Rhea" id="RHEA:16585"/>
            <dbReference type="Rhea" id="RHEA-COMP:9928"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="Rhea" id="RHEA-COMP:10475"/>
            <dbReference type="Rhea" id="RHEA-COMP:14568"/>
            <dbReference type="Rhea" id="RHEA-COMP:14569"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="ChEBI" id="CHEBI:29919"/>
            <dbReference type="ChEBI" id="CHEBI:33722"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:78809"/>
            <dbReference type="ChEBI" id="CHEBI:83100"/>
            <dbReference type="EC" id="2.8.1.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="6">Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="pathway">
        <text evidence="6">Protein modification; protein lipoylation via endogenous pathway; protein N(6)-(lipoyl)lysine from octanoyl-[acyl-carrier-protein]: step 2/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the radical SAM superfamily. Lipoyl synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.8" evidence="6"/>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93215">
        <property type="protein sequence ID" value="PRC93215"/>
        <property type="gene ID" value="S2091_1953"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00538">
        <property type="reaction ID" value="UER00593"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016992">
        <property type="term" value="F:lipoate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102552">
        <property type="term" value="F:lipoyl synthase activity (acting on glycine-cleavage complex H protein"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102553">
        <property type="term" value="F:lipoyl synthase activity (acting on pyruvate dehydrogenase E2 protein)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009249">
        <property type="term" value="P:protein lipoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00206">
        <property type="entry name" value="Lipoyl_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003698">
        <property type="entry name" value="Lipoyl_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10949">
        <property type="entry name" value="PTHR10949"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005963">
        <property type="entry name" value="Lipoyl_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00271">
        <property type="entry name" value="lipoyl_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00510">
        <property type="entry name" value="lipA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6" id="KW-0408">Iron</keyword>
    <keyword evidence="5 6" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Radical SAM core" evidence="8">
        <location>
            <begin position="84"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="73"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="78"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="84"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="99"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="103"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="106"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="313"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC93215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="330" mass="36777" checksum="583A153ED3A623DE" modified="2018-07-18" version="1">MTNPTDIATPVTPEYNPSEKQKGANKTSRIPIKIVPYEKLAKPSWIRVKAASPNTRFYEIKDILRASGLVTVCEEASCPNIGECFGKGTATFMIMGDKCTRRCPFCDVGHGRPDPLDENEPLNLATTISKLKLSYVVITSVDRDDLRDGGAGHFAACIEKVRELSPHTRIEILTPDFRGRMDRALEILKASPPDVMNHNLETVPRLYKEARPGSDYEYSLNLLKRFKEAHPNTPTKSGIMVGLGETDEEILQVMRDLRANDVDMLTIGQYLMPSGNHLPVRRYVHPDTFKMFEEEAYKMGFAHAAVGAMVRSSYHADVQAHEAGVVVDGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZX6</accession>
    <name>A0A2S9GZX6_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Glutathione synthetase</fullName>
            <ecNumber evidence="10">6.3.2.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">GSH synthetase</fullName>
            <shortName evidence="10">GSH-S</shortName>
            <shortName evidence="10">GSHase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Glutathione synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">gshB</name>
        <name evidence="13" type="ORF">S2091_2027</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + glutathione + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13557"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:58173"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="10">Sulfur metabolism; glutathione biosynthesis; glutathione from L-cysteine and L-glutamate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the prokaryotic GSH synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.3" evidence="10"/>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93289">
        <property type="protein sequence ID" value="PRC93289"/>
        <property type="gene ID" value="S2091_2027"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00142">
        <property type="reaction ID" value="UER00210"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004363">
        <property type="term" value="F:glutathione synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00162">
        <property type="entry name" value="GSH_S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006284">
        <property type="entry name" value="Glut_synth_pro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004218">
        <property type="entry name" value="GSHS_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004215">
        <property type="entry name" value="GSHS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21621:SF4">
        <property type="entry name" value="PTHR21621:SF4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02955">
        <property type="entry name" value="GSH-S_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02951">
        <property type="entry name" value="GSH-S_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="SSF52440"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01380">
        <property type="entry name" value="glut_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 10" id="KW-0317">Glutathione biosynthesis</keyword>
    <keyword evidence="3 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9" id="KW-0464">Manganese</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 10 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-grasp" evidence="12">
        <location>
            <begin position="121"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PRC93289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="310" mass="34164" checksum="F8ECAA72A15F3471" modified="2018-07-18" version="1">MKIAFLTDPLDDFKIYKDTTFAMMREAAKRGHELYAFMPKDMALEGAQVVAQVRRIHLTGQEVWYQAEAPEERRLNEFDAVLQRKDPPFDMEYVYATYLLELAEQSGARVFNKPAAIRGHNEKLSIAQFPQFTAPTLVTSDEVRLRRFHAEHQDIILKPLDGMGGAGVFKVSADGLNLGSIIETLTGNGTRTIMAQRYIPEITLGDKRILLIGGKVVPFSLARIPQGSEVRGNLAAGGVGVAQPLSARDTEIAEALAPILAQRGLLLVGCDVIGNFLTEVNVTSPTCFQEITQQTGFDVAALFIDELERA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0D3</accession>
    <name>A0A2S9H0D3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1805</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93418">
        <property type="protein sequence ID" value="PRC93418"/>
        <property type="gene ID" value="S2091_1805"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="93" mass="10376" checksum="4298A69D1E34EF74" modified="2018-07-18" version="1">MVYLEINLQVAPQDRPAAAAIYTRFKVPFLTQAKGALSKELLIREEDVQVLHGFDSDENAKSYLGSTMFTNDVVTALKPLLTSAPDVRIYQTM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0G6</accession>
    <name>A0A2S9H0G6_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Pvc16_N domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1827</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93440">
        <property type="protein sequence ID" value="PRC93440"/>
        <property type="gene ID" value="S2091_1827"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025351">
        <property type="entry name" value="Pvc16_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14065">
        <property type="entry name" value="Pvc16_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pvc16_N" evidence="1">
        <location>
            <begin position="8"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="191" mass="21393" checksum="9844178803A11111" modified="2018-07-18" version="1">MINAAISHLANQLNQQFKNNFQLVEDIVVVSNLVESDGSPAINANNKLALTLVNIEKDSMPYRPNQTSRGRDDRQLVHSSPLYLNLYLMMSANFGSGNYKEALKTISQAIGFFQQQAVFDQQNSPGLDPRIEKLILDMENLKIPDLNNLWSLIGGRYMPSAFYKVRMITVDAGAIIGQVPVITDPRNDLIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0G8</accession>
    <name>A0A2S9H0G8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2094</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93356">
        <property type="protein sequence ID" value="PRC93356"/>
        <property type="gene ID" value="S2091_2094"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="98" mass="11051" checksum="D71DE36C94AAFFEB" modified="2018-07-18" version="1">MILTTLEQPILAAVPALAAFTFKFLLIGGFVAFVILFKPMLLGIWRATKLHLKQYFSKEQQNLRLNLKNRQLIYKAVNDLDGHSPSLAAEIRALSARI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0I8</accession>
    <name>A0A2S9H0I8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Universal stress protein UspA and related nucleotide-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1860</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal stress protein A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93473">
        <property type="protein sequence ID" value="PRC93473"/>
        <property type="gene ID" value="S2091_1860"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006015">
        <property type="entry name" value="Universal_stress_UspA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006016">
        <property type="entry name" value="UspA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00582">
        <property type="entry name" value="Usp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01438">
        <property type="entry name" value="UNVRSLSTRESS"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Usp" evidence="2">
        <location>
            <begin position="1"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="145" mass="16155" checksum="9F1769DC25447926" modified="2018-07-18" version="1">MFKHILVPTDGSEISKRVVRDCIKFAKEINAEVIGFTAMPEYSVYAYEAEVLLDAMEQFTNQCIANATRNLDDIKAVAKEFGVKCETYYLTSDFPYAAIIQAAQDKNCDLIAMAAHGRKGIKGILLGSETQKVLTHCQIPVLVFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0M6</accession>
    <name>A0A2S9H0M6_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RraB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1887</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93500">
        <property type="protein sequence ID" value="PRC93500"/>
        <property type="gene ID" value="S2091_1887"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.970">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036701">
        <property type="entry name" value="RraB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009671">
        <property type="entry name" value="RraB_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06877">
        <property type="entry name" value="RraB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89946">
        <property type="entry name" value="SSF89946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RraB" evidence="1">
        <location>
            <begin position="31"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="132" mass="15257" checksum="9571D12C43ECE731" modified="2018-07-18" version="1">MGIFKFFSNEPKKFVPRESFVEITNRQLTMTPQTLMQLRKYNVTPEKELKLEFFFYTNTSAKADALATALLNRSYQVNHGPSASDKNIQIITGWTAKFPMNDSSVLEWTKDMCELGFEHDCEFDGWGTNPEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0R2</accession>
    <name>A0A2S9H0R2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative regulatory protein, FmdB family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1570</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93569">
        <property type="protein sequence ID" value="PRC93569"/>
        <property type="gene ID" value="S2091_1570"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013429">
        <property type="entry name" value="Regulatory_FmdB_Zinc_ribbon"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09723">
        <property type="entry name" value="Zn-ribbon_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00834">
        <property type="entry name" value="CxxC_CXXC_SSSS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02605">
        <property type="entry name" value="CxxC_CxxC_SSSS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CxxC_CXXC_SSSS" evidence="2">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="108" mass="11013" checksum="C0FDF00BE12694FE" modified="2018-07-18" version="1">MPIYAYRCNECGFAKDVLQKMSDPVLTDCPSCGKSEFKKQVTAAGFQLKGSGWYVTDFKGASGGTSVAASDAKKTDSGKSDSASSAATTTAAATSSTESSSTTPSATK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1I1</accession>
    <name>A0A2S9H1I1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Response regulator receiver domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1450</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93841">
        <property type="protein sequence ID" value="PRC93841"/>
        <property type="gene ID" value="S2091_1450"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="7"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="131" mass="14279" checksum="88A9045A34FA9AC4" modified="2018-07-18" version="1">MAPTLTKILYVEDDLDIQSVAKIALEIVGGLTLLSCSSGKEALNPSTIVFAPDLMLLDVMMPEMDGPTTLKHLRSIPSLKNTPVIFMTAKVQVSEVAYYKSLGAIGVIAKPFDPMQLAEQIRQLWNECVSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1L8</accession>
    <name>A0A2S9H1L8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1494</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93885">
        <property type="protein sequence ID" value="PRC93885"/>
        <property type="gene ID" value="S2091_1494"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="38" mass="4673" checksum="E580BC222FE6FD37" modified="2018-07-18" version="1">MGCLPYFEEYRLEHLLFSETIPNYTKKISYFKLIDKLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1Y0</accession>
    <name>A0A2S9H1Y0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1152</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC93979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93979">
        <property type="protein sequence ID" value="PRC93979"/>
        <property type="gene ID" value="S2091_1152"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="41" mass="4619" checksum="0995546E8956D4D2" modified="2018-07-18" version="1">MKKILKQSYTAKLKELAVKRVKDRESIATVITELVGRSDAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1Z6</accession>
    <name>A0A2S9H1Z6_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Transport permease protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_1184</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell inner membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the ABC-2 integral membrane protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94011">
        <property type="protein sequence ID" value="PRC94011"/>
        <property type="gene ID" value="S2091_1184"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC_2_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000412">
        <property type="entry name" value="ABC_2_transport"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006648">
        <property type="entry name" value="DrrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00164">
        <property type="entry name" value="ABC2TRNSPORT"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51012">
        <property type="entry name" value="ABC_TM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="23"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="53"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="83"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="108"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="133"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="171"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="222"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="domain" description="ABC2_membrane" evidence="7">
        <location>
            <begin position="4"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC94011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="251" mass="27844" checksum="D47911476474C1DE" modified="2018-07-18" version="1">MIGFQTLFYKEILRFWKVATQTITAPIMTALLYLLIFGHVLDSRVQVYPGVRYTAFLVPGLVMMSVLQNAFANASSSLMQSKITGNLVFILLPPLSYWELFSAYVLASIVRGLVVGLGVFVITAWFADLSFVAPLWIVVFSLLGAAMLGTMGLIAGIWAEKFDQLAAFQNFLIMPATFLSGVFYSIHSLPPIWQAVSRFNPFFYMIDGFRYGFFGQSDVDPLHSLLIVSAFSALLAGIALTMLKNGYKLRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H258</accession>
    <name>A0A2S9H258_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF4440 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1232</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94059">
        <property type="protein sequence ID" value="PRC94059"/>
        <property type="gene ID" value="S2091_1232"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027843">
        <property type="entry name" value="DUF4440"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14534">
        <property type="entry name" value="DUF4440"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4440" evidence="1">
        <location>
            <begin position="11"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="125" mass="13873" checksum="CA75425A859CBDF1" modified="2018-07-18" version="1">MKVTDPKNLNKHFNELFRADDLDGMMALYESSAVLCLASGHVLNGSEQIREQMKTLLALRGELTSEHLSCVQRDDLAMLHAKWQFKGSDSAGNAIDIGGYSSKLAKKGEDGAWRYVMDLPVAFRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2C3</accession>
    <name>A0A2S9H2C3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Sulfotransferase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1283</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94110">
        <property type="protein sequence ID" value="PRC94110"/>
        <property type="gene ID" value="S2091_1283"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="304" mass="34794" checksum="822E432B34F919C3" modified="2018-07-18" version="1">MDVAIKETGISMEMTGRSSRDWRELGNKGLFVIGHARTGTTVLQNALNDSKNILLFGEANFYVDKGQPDFRARFNKWHDLNGNQPTKSTYCPAVFDGDGTWEDYWVHFSHFYRCVGEKIIFNPTETSAQCDALMGFFAAHFFTGQFIFCFRNPIDVLFSVRKLAEYHGTPMTDVSIMISYLSVLRLYLTMVRLFPNVHVVFHEEPSKECFDAIGQSLDVGLNHVMSYYQTERVSRHSIDEIPAGCRDRVKELDSLYNHLRDRARGGFVLPQLEQNRYNYSPTHPTPLGGLYNATEMLLRDLAVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2S1</accession>
    <name>A0A2S9H2S1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Thioesterase superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0906</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94285">
        <property type="protein sequence ID" value="PRC94285"/>
        <property type="gene ID" value="S2091_0906"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006683">
        <property type="entry name" value="Thioestr_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03061">
        <property type="entry name" value="4HBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4HBT" evidence="1">
        <location>
            <begin position="47"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="148" mass="17177" checksum="B742747A2BF5C5E3" modified="2018-07-18" version="1">MRITCFEKNYPIRFSHCDPAGIVYFPQYLVLSNWLVEDWFTEGLGIDFSHFICARRLGLPIVKLENEFLAPSRQGELLTFRLELQNLGRRSLEVLISARFGDQVRMQSKQVMVITSLESGKSIVFPDDVRQQLQRFTEQTKLTEMVAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2S6</accession>
    <name>A0A2S9H2S6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_1339</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the IMPACT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94166">
        <property type="protein sequence ID" value="PRC94166"/>
        <property type="gene ID" value="S2091_1339"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023582">
        <property type="entry name" value="Impact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001498">
        <property type="entry name" value="Impact_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036956">
        <property type="entry name" value="Impact_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015269">
        <property type="entry name" value="UPF0029_Impact_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16301">
        <property type="entry name" value="PTHR16301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09186">
        <property type="entry name" value="DUF1949"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01205">
        <property type="entry name" value="UPF0029"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="SSF54980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UPF0029" evidence="2">
        <location>
            <begin position="15"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1949" evidence="3">
        <location>
            <begin position="134"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF09186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC94166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="196" mass="21530" checksum="7266FE5A6C7AD839" modified="2018-07-18" version="1">MYQLAAPVSTEIEIKKSRFIGQLYPVSSRTEARAKLAELRVQHPNAVHICWVLICEGESGLDDDGEPSGTAARPMYNVLVHKELMNVLAVVVRYWGGIKLGAGGLARAYSQAISDASKLAELVAVEVMCLRSFTVQFSDESHLRRLCEQFAVTVQAVDYAELVTLHLQIKLSQAALFEQAAFDALRGALKNVTELP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H333</accession>
    <name>A0A2S9H333_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1015</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94394">
        <property type="protein sequence ID" value="PRC94394"/>
        <property type="gene ID" value="S2091_1015"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="331" mass="36818" checksum="B24A65182AD8B642" modified="2018-07-18" version="1">MTILASFSFSSSILDTHVFQRECDVMLFADGRISDQAGANLIIDTAPKIAVQEVKVVTTDRRTLTTDVAIGYAGASALVALSVLNFSAHVLRHLVGETLPSIEQIVSFVAEALKVSITEYSNNRHQATNLRLLVGGYDQSKQEVVLRQITLKCVSGKYFTEIDVPSTSLTIASGPTDDNLYERIQNQVLSVSRDEDASCDAEDLVARQVELFVRDNSKDRPYGGQLQVCRIGAFGAQLATTKFWDKSYRSDDLPADWNHGDYRSLMLGYDVFDLRVGQCDFQPHYIYHLPDSDGTPWAKGPIKIEERPADDGDVFSRPRKGLLDIRNFSKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H361</accession>
    <name>A0A2S9H361_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1040</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94419">
        <property type="protein sequence ID" value="PRC94419"/>
        <property type="gene ID" value="S2091_1040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="22"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="104"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="138" mass="16041" checksum="DB6748A73B0BEAA9" modified="2018-07-18" version="1">MEIPKNPPKIGKHEQIDKEFGVWWWFLNTWGTASFLLFLACLGTGEYRHTCALISSILLTWSYFFGLSAFPPFINRLRSQSTEAAKTLEKKIFFEHFVKRPFDFLPLLIGCATLGSIAFLPAFYGRWYLYVSILNFKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H377</accession>
    <name>A0A2S9H377_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Methylenetetrahydrofolate reductase</fullName>
            <ecNumber evidence="10">1.5.1.20</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">S2091_1049</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2 10">
            <text>(6S)-5-methyl-5,6,7,8-tetrahydrofolate + NAD(+) = (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:19821"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:18608"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.5.1.20"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>(6S)-5-methyl-5,6,7,8-tetrahydrofolate + NADP(+) = (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:19817"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:18608"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.5.1.20"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3 10">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4 10">One-carbon metabolism; tetrahydrofolate interconversion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 10">Belongs to the methylenetetrahydrofolate reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.5.1.20" evidence="10"/>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94428">
        <property type="protein sequence ID" value="PRC94428"/>
        <property type="gene ID" value="S2091_1049"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00193"/>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106312">
        <property type="term" value="F:methylenetetrahydrofolate reductase NADH activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106313">
        <property type="term" value="F:methylenetetrahydrofolate reductase NADPH activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009086">
        <property type="term" value="P:methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035999">
        <property type="term" value="P:tetrahydrofolate interconversion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00537">
        <property type="entry name" value="MTHFR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029041">
        <property type="entry name" value="FAD-linked_oxidoreductase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003171">
        <property type="entry name" value="Mehydrof_redctse-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004620">
        <property type="entry name" value="MTHF_reductase_bac"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02219">
        <property type="entry name" value="MTHFR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51730">
        <property type="entry name" value="SSF51730"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00676">
        <property type="entry name" value="fadh2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0274">FAD</keyword>
    <keyword evidence="6 10" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="9" id="KW-0520">NAD</keyword>
    <keyword evidence="8 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00006743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC94428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="275" mass="30198" checksum="7C8EDE3C86A783FA" modified="2018-07-18" version="1">MPQPNFSIEFFPPKTPEGVEKLRIVRAKLAVLNPTYFSVTFGAGGTTQQGTLDTVLEMRAEGFAAAPHLSCVGGSAESIRAILQQYKANDIHRLVALRGDLPSGYGAGGEFRYASELVEFIRKETGDWFRIEVAAYPEMHPQARSPQDDLKNFARKIQAGADAAITQYFYNADAYFQFVDAANKLGVNVPIVAGIMPITNYTQLMRFSEMCGAEIPRWVRLKLASYGDDSASIKAFGLDVVTQLCERLLAGGAPGLHFYSMNQAVATSAIWQRLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3E3</accession>
    <name>A0A2S9H3E3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ABC-type sugar transport system periplasmic component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0508</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94505">
        <property type="protein sequence ID" value="PRC94505"/>
        <property type="gene ID" value="S2091_0508"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008643">
        <property type="term" value="P:carbohydrate transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006059">
        <property type="entry name" value="SBP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13416">
        <property type="entry name" value="SBP_bac_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015665111" evidence="1">
        <location>
            <begin position="32"/>
            <end position="428"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="428" mass="46823" checksum="38F56E849F221348" modified="2018-07-18" version="1">MKFSWLAASVKLVLAICLVSFSFILVPSALAAPTQKIELWTLSMKPKFIPYFQQIVQKFEAQHPGIEVEWVDFPWDILQLKLITAIAAGTPPSLVNLNVPWAEEYARDSLIVPVDSMMLNKAMYTKAALEDLTFNGHIYGFPHYSNVNVIAYNSAIFAEAGLKQAPKSLAEELAFAKQIYAKTGKAGYAPTLGKIDGFFLQQGLDVVKNGRAVFNSPQHVALIKKLADAYQAGGILKDQLFSEDSFPSAIDAYKGGRLGMLVSAPTALKRIELDAKDIYAVTKVAPAPLGPTNNADGGWMFHYAVPKGVNPKLYPAIATFAEFLTNDENQLAFAKLAGVMPTTVQALANPYFMQTPAHASAAEQALPIAAASMKFSRSLYVAGLDDYDEMRRVMVKAVEAGMTGKQDIQQALDEAVRIWNKKLQQQAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3I1</accession>
    <name>A0A2S9H3I1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0496</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94493">
        <property type="protein sequence ID" value="PRC94493"/>
        <property type="gene ID" value="S2091_0496"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015462516" evidence="1">
        <location>
            <begin position="21"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="135" mass="13420" checksum="800D9810D972B76F" modified="2018-07-18" version="1">MNKLITTFVAATLVMGAAFAQTPATSTAPATPKPAAAPVTMTAPTKTVVAASTAKPATALTVLKTEKSTQIASKTAATKTATKTTTKATPVVATAPVASATSKATVVASDKKVTQTVAMKKDDTKAAVTKKSAAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3N9</accession>
    <name>A0A2S9H3N9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Bacterial extracellular solute-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0607</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94604">
        <property type="protein sequence ID" value="PRC94604"/>
        <property type="gene ID" value="S2091_0607"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="81" mass="9053" checksum="D9F85426152D4901" modified="2018-07-18" version="1">MAIFFLKRLIANTFIQPRKRNFSWQVAGLVSVPLPDTLEVHPHYGLAILSENTDALRFSLFVLSAQGQAILARFGFLPIAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3Q2</accession>
    <name>A0A2S9H3Q2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphoesterase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0499</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94496">
        <property type="protein sequence ID" value="PRC94496"/>
        <property type="gene ID" value="S2091_0499"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007312">
        <property type="entry name" value="Phosphoesterase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31956">
        <property type="entry name" value="PTHR31956"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04185">
        <property type="entry name" value="Phosphoesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015524220" evidence="1">
        <location>
            <begin position="31"/>
            <end position="690"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="690" mass="74494" checksum="576CBD65E0C56665" modified="2018-07-18" version="1">MNFRLKGMRELGIGLSSLALFQMSFGSALAQSAPSAADHRTQSPIKHVIVIIGENHSFDNVFATYEPKNGHGIWNLRSLGIVNKDGSPGPNFKLAQQKAATDTTADSFLLSPAKAAFPGGVLPAPLTGGPKSSYITGNSLQLAQESENGLPADYYQYLVSGGTGQASHVPDQRIPNVNALPPGPFQLTNATTLNYHDYSASPVHRFYQMWQQLDCNINQATPLRPSGCDSSLFSWVETVVGAGSNGDAQPANFSAEYSPTAKTTGEGSTALGFYNMHTGDVPYFKHLADHYAMSDNFHQSVNGGTGANHIMIGHGDAIWFSDGAGNPMPPPHNVTVAAGSKNAGIVDEVENPNPAAGTNNWYAEDGYGGGSYGSPSYGGGSYTNCSDTRQPGVAPIVDYLKSLPKPIASKCEPGHYYLLNNYNPGYFGNGNNAFTDNSPNNTVFTIPPSTVPSIGDSLNKADVSWKYYGDQWNNYVGDPYQLNYGAQGANTDEYCNICNPFQYDTSIMTNPAMVAAHIQDTTNLYADISAGTLPAVSFVKPSGLVDGHPSSSKLDLFEGFSKKIIDAVKANPKLWADTAIFVTFDEGGGYYDSGYVQPVDFFGDGTRIPFIVVSPLAKQGHVSHEYTDHVSILKFIERNWRLKPVSNRSRDNFPNPIAHERNPYVPVNSPAIGDLFDMFDFDSAPNQWRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3V5</accession>
    <name>A0A2S9H3V5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="10">TonB-Xanth-Caul: TonB-dependent receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">S2091_0653</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94650">
        <property type="protein sequence ID" value="PRC94650"/>
        <property type="gene ID" value="S2091_0653"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010104">
        <property type="entry name" value="TonB_rcpt_bac"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01782">
        <property type="entry name" value="TonB-Xanth-Caul"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="3 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 10" id="KW-0675">Receptor</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="2 6" id="KW-0798">TonB box</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015696239" evidence="7">
        <location>
            <begin position="26"/>
            <end position="919"/>
        </location>
    </feature>
    <feature type="domain" description="Plug" evidence="9">
        <location>
            <begin position="73"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="8">
        <location>
            <begin position="443"/>
            <end position="918"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC94650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="919" mass="98758" checksum="E18414C24BAC1CD5" modified="2018-07-18" version="1">MKVQRTSIAIAVTMALTTIIMPAQAQQADSKPVDVVQSSLTVPASTAPDSTAPVSQVIVTGIRASREQSLKMKRDADSVMDVVTAEDIGKLPDKNVADAVQRVPGVNISSGSGGEGGFSENDRVSIRGTNPSLTQTTINGHTVSTGDWYIGDQQGTVGRSVSFTLLPSEIVGSVEVQKSSQADYIEGGTVGNVNVVTRATLDFKKQLTVEATVQGMYADLPAKTSPQLNALVNWKNDENTFGVLFQLFSEKRNERRDGQELFLLGSNYIGNPSDNSAAVVAAHSDLNGVKYPSQIGSAAFTQQSTRTGGLLDFQFKPLTGVTLDINGFYSRFNTDTFDTNFMASPYNLLSQGVSPNSYTVKNNTLVAASFPNTVFNPNDPNPGADMPFPGVRDSIYRPNAGSTAGYLDFDSKIRLSDTLTITSKVGYTRGTGETPHDYGYEAYLINSPMSYQLNGTNGPANVSFPGVNTANFNNPANVTNGGSWSQSAKVTDQETYGQVDAILTLDNGYFESAKFGVRYAEHKRTAYDVNYGCSTNPNDPCFTNPGQTLPAPAWNGTVSPGNFGAGIGAGPGFLSNFWVLNPANIASWQQQYDSVSLGPSYQNNFEIKEKDTAAYAMTNLVGDHWRGNIGLRLVNTNQFGTAYDYNSATSSFAPVTSTHNYVDVLPSANLKFDLSKDLVARFAASTTMSRADYSSLSPAVVLNNLNLTGSGGNSDLKAVKSNNVDATLEWYFAPQSILSAGLFYMDMPSYITFGNNVRPFLNTTTDQIANFLVTSPYNIAAKNDGLELAWQQSFGSGFGGLVNYTYADGHDASGNALVGSSKNTGNVEVYYENAGFSTRLAYNYRSSFLVGLANVTPQYAAGIGTLAASINYKINDNFSITFDGLNLNNPVIKYYSNAEQPEAFYSNGRQFFLGVRMSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H409</accession>
    <name>A0A2S9H409_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">S-adenosylmethionine decarboxylase proenzyme</fullName>
            <shortName evidence="10">AdoMetDC</shortName>
            <shortName evidence="10">SAMDC</shortName>
            <ecNumber evidence="10">4.1.1.50</ecNumber>
        </recommendedName>
        <component>
            <recommendedName>
                <fullName evidence="10">S-adenosylmethionine decarboxylase beta chain</fullName>
            </recommendedName>
        </component>
        <component>
            <recommendedName>
                <fullName evidence="10">S-adenosylmethionine decarboxylase alpha chain</fullName>
            </recommendedName>
        </component>
    </protein>
    <gene>
        <name evidence="10" type="primary">speH</name>
        <name evidence="11" type="ORF">S2091_0694</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>H(+) + S-adenosyl-L-methionine = CO2 + S-adenosyl 3-(methylsulfanyl)propylamine</text>
            <dbReference type="Rhea" id="RHEA:15981"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57443"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="EC" id="4.1.1.50"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>pyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
        </cofactor>
        <text evidence="10">Binds 1 pyruvoyl group covalently per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="10">Amine and polyamine biosynthesis; S-adenosylmethioninamine biosynthesis; S-adenosylmethioninamine from S-adenosyl-L-methionine: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.</text>
    </comment>
    <comment type="PTM">
        <text evidence="10">Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.50" evidence="10"/>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94691">
        <property type="protein sequence ID" value="PRC94691"/>
        <property type="gene ID" value="S2091_0694"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00331">
        <property type="reaction ID" value="UER00451"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004014">
        <property type="term" value="F:adenosylmethionine decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006557">
        <property type="term" value="P:S-adenosylmethioninamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008295">
        <property type="term" value="P:spermidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.750">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00464">
        <property type="entry name" value="AdoMetDC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042286">
        <property type="entry name" value="AdoMetDC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003826">
        <property type="entry name" value="AdoMetDC_fam_prok"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042284">
        <property type="entry name" value="AdoMetDC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016067">
        <property type="entry name" value="S-AdoMet_deCO2ase_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017716">
        <property type="entry name" value="S-AdoMet_deCOase_pro-enz"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33866">
        <property type="entry name" value="PTHR33866"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02675">
        <property type="entry name" value="AdoMet_dc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56276">
        <property type="entry name" value="SSF56276"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03330">
        <property type="entry name" value="SAM_DCase_Bsu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 10" id="KW-0068">Autocatalytic cleavage</keyword>
    <keyword evidence="2 10" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="7 10" id="KW-0456">Lyase</keyword>
    <keyword evidence="5 10" id="KW-0620">Polyamine biosynthesis</keyword>
    <keyword evidence="9 10" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 10" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="8 10" id="KW-0704">Schiff base</keyword>
    <keyword evidence="4 10" id="KW-0745">Spermidine biosynthesis</keyword>
    <keyword evidence="6 10" id="KW-0865">Zymogen</keyword>
    <feature type="chain" id="PRO_5023360444" description="S-adenosylmethionine decarboxylase beta chain" evidence="10">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023360443" description="S-adenosylmethionine decarboxylase alpha chain" evidence="10">
        <location>
            <begin position="69"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with substrate; via pyruvic acid" evidence="10">
        <location>
            <position position="69"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; for processing activity" evidence="10">
        <location>
            <position position="74"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor; for catalytic activity" evidence="10">
        <location>
            <position position="89"/>
        </location>
    </feature>
    <feature type="site" description="Cleavage (non-hydrolytic); by autolysis" evidence="10">
        <location>
            <begin position="68"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="modified residue" description="Pyruvic acid (Ser); by autocatalysis" evidence="10">
        <location>
            <position position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC94691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="127" mass="13529" checksum="960C30B4E707598C" modified="2018-07-18" version="1">MTHPVYEPSGQHLFADLYGINPDKLNDAATVELLLRESANAAGATILCSHFHAFGSGQGVTGVVLLAESHISIHTWPEFGFAAVDIFMCGNSKPDRALDVIQSALQASKSSVQTISRGHAPTIQSNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H441</accession>
    <name>A0A2S9H441_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_0752</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94749">
        <property type="protein sequence ID" value="PRC94749"/>
        <property type="gene ID" value="S2091_0752"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000485">
        <property type="entry name" value="AsnC-type_HTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019888">
        <property type="entry name" value="Tscrpt_reg_AsnC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019887">
        <property type="entry name" value="Tscrpt_reg_AsnC/Lrp_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01037">
        <property type="entry name" value="AsnC_trans_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13404">
        <property type="entry name" value="HTH_AsnC-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00033">
        <property type="entry name" value="HTHASNC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00344">
        <property type="entry name" value="HTH_ASNC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50956">
        <property type="entry name" value="HTH_ASNC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH asnC-type" evidence="4">
        <location>
            <begin position="8"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC94749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="157" mass="17503" checksum="4D775B115F3445E8" modified="2018-07-18" version="1">MKTVKIILDELDRRILNALQDDAAQTNQELAELVHASAPTCLRRVKRLVDGGVIARQVVLLDPEKVGASLSAIVEITLDVQASERLIEFEKLVATEAAVQQCYRVSPGPDFVLIIQVADMAAYHELAHRLFAQHANVRNVRSFFSVLRSKFETRIAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H446</accession>
    <name>A0A2S9H446_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0755</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94752">
        <property type="protein sequence ID" value="PRC94752"/>
        <property type="gene ID" value="S2091_0755"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013196">
        <property type="entry name" value="HTH_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026881">
        <property type="entry name" value="WYL_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08279">
        <property type="entry name" value="HTH_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13280">
        <property type="entry name" value="WYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH_11" evidence="1">
        <location>
            <begin position="6"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="domain" description="WYL" evidence="2">
        <location>
            <begin position="139"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="229" mass="25987" checksum="4C0EAB8749C6F587" modified="2018-07-18" version="1">MSRAERLLDLIQLLREHRYPVTGTVLCTKLGVSLRTLYRDIKTLQEQGAHIEGEPGLGYLLRPGFILPPLMLTEEEIEALLLGSRWVAQRGDAKLGGAAQSALSKIIAVLPGELRDPRDTSTLLVGPGEPIATGSLELPLIRQAICAEHKLHITYRDLKEDESSRTIWPFAVGFFDDVRIVVAWCELRLCFRHFRVDRITSIKVSEQRYPRNRQSLLKEWRATEKIPVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H484</accession>
    <name>A0A2S9H484_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0746</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94743">
        <property type="protein sequence ID" value="PRC94743"/>
        <property type="gene ID" value="S2091_0746"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="252" mass="28188" checksum="F34DAE2430F458BB" modified="2018-07-18" version="1">MISVPEAIANKNWIGHPIYEAMGKWGKPLVTPVGDGTGLYQWGWNSKYAYNAQVGTSSSSNGVQTTYYQKQIGTAECQIVVNADSNGIITHFETRGACSDLYWGSGSATPDAESAAKGKLLVESLAKAKELNARYEMVYTKPEYAELFSEAHSDDNSYFTVGPDVVVGKLTPHQIELFSKWRGEMDSVVKDYQVFLRSTQDRADKSQADNIEFMNKATPPATEKNNRKLQNEYITYRNAKALSMYVRRTYLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4A1</accession>
    <name>A0A2S9H4A1_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">N-succinylglutamate 5-semialdehyde dehydrogenase</fullName>
            <ecNumber evidence="4">1.2.1.71</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Succinylglutamic semialdehyde dehydrogenase</fullName>
            <shortName evidence="4">SGSD</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">astD</name>
        <name evidence="9" type="ORF">S2091_0005</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>H2O + N-succinyl-L-glutamate 5-semialdehyde + NAD(+) = 2 H(+) + N-succinyl-L-glutamate + NADH</text>
            <dbReference type="Rhea" id="RHEA:10812"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58520"/>
            <dbReference type="ChEBI" id="CHEBI:58763"/>
            <dbReference type="EC" id="1.2.1.71"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Amino-acid degradation; L-arginine degradation via AST pathway; L-glutamate and succinate from L-arginine: step 4/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the aldehyde dehydrogenase family. AstD subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.71" evidence="4"/>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94810">
        <property type="protein sequence ID" value="PRC94810"/>
        <property type="gene ID" value="S2091_0005"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00185">
        <property type="reaction ID" value="UER00282"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043824">
        <property type="term" value="F:succinylglutamate-semialdehyde dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019544">
        <property type="term" value="P:arginine catabolic process to glutamate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019545">
        <property type="term" value="P:arginine catabolic process to succinate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd07095">
        <property type="entry name" value="ALDH_SGSD_AstD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01174">
        <property type="entry name" value="Aldedh_AstD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017649">
        <property type="entry name" value="SuccinylGlu_semiald_DH_AstD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11699:SF197">
        <property type="entry name" value="PTHR11699:SF197"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03240">
        <property type="entry name" value="arg_catab_astD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
        <property type="entry name" value="ALDEHYDE_DEHYDR_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0056">Arginine metabolism</keyword>
    <keyword evidence="3 4" id="KW-0520">NAD</keyword>
    <keyword evidence="2 4 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldedh" evidence="8">
        <location>
            <begin position="15"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="active site" evidence="4 5">
        <location>
            <position position="249"/>
        </location>
    </feature>
    <feature type="active site" evidence="4 6">
        <location>
            <position position="283"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="226"/>
            <end position="231"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022503"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC94810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="492" mass="52344" checksum="90AF81B8475B1E5B" modified="2018-07-18" version="1">MNHKTNSSNYINGAWLAGSGESFSVINPADGQTVWQGNAADENDVQQACSAARASFSAWAQTSLDERIAICAKFRDLLKQHTEELALLIAQEVGKPMWEARTEVATMANKIDISVQSYQARTGVVSSKVADGDAVLRHRPHGVFAVFGPYNFPGHLPNGHIVPALIAGNTLVFKPSEYAPQTAIKTVQLWAQAGLPNGVLNLVNGGKNTGIALSKNTDIDGVLFTGSYQTGVILHKQFAGQPGKMLALEMGGNNALVMWDVKDIDAAVHHTIFSAFVSAGQRCTCARRLVIPNTAQGQAFLDRLVQVAAAIRVGKSDAEPAPFMGPVVSSVIAQRLLDGQAELIAKGGKSLLAMRHLQADTGFLSAGIVDVTDAKNIPDEEWFGPLLQVIRVADFASAIKVANATNYGLAAGLLSDDANLWQQFQTHIRAGVVNWNRPTTGAASTAPFGGVGNSGNHRPSAYYAADYCAYPVASIETNLLEMPKQLSPGLVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4B0</accession>
    <name>A0A2S9H4B0_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">UPF0310 protein S2091_0756</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0756</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0310 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94753">
        <property type="protein sequence ID" value="PRC94753"/>
        <property type="gene ID" value="S2091_0756"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00771">
        <property type="entry name" value="UPF0310"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002740">
        <property type="entry name" value="EVE_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022996">
        <property type="entry name" value="UPF0310"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01878">
        <property type="entry name" value="EVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="SSF88697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EVE" evidence="2">
        <location>
            <begin position="4"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="142" mass="15964" checksum="59E7AA5B80204C3F" modified="2018-07-18" version="1">MSRNWIAVASAEHVRIGREVGFMQVCHGKAAPLHRIKPGDRVAYYSPTVEFGSKHKLQAFTAIGVVKNNEPYQVEMTPGFCPFRRDVMWFPAKEAVIQPLLGSLDFSRGITNWGYQLRFGLFSVSEHDMQLIAAAMGAVFFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4C8</accession>
    <name>A0A2S9H4C8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Cytochrome c</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">S2091_0037</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
        </cofactor>
        <text evidence="8">Binds 3 heme c groups covalently per subunit.</text>
    </comment>
    <comment type="PTM">
        <text evidence="9">Binds 3 heme groups per subunit.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94842">
        <property type="protein sequence ID" value="PRC94842"/>
        <property type="gene ID" value="S2091_0037"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014353">
        <property type="entry name" value="Membr-bd_ADH_cyt_c"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00034">
        <property type="entry name" value="Cytochrom_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000018">
        <property type="entry name" value="Mb_ADH_cyt_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="2 8 10" id="KW-0349">Heme</keyword>
    <keyword evidence="6 9 10" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 9 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Cytochrome c" evidence="11">
        <location>
            <begin position="43"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="11">
        <location>
            <begin position="188"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="11">
        <location>
            <begin position="315"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="binding site" description="covalent" evidence="8">
        <location>
            <position position="57"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="8">
        <location>
            <position position="60"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="9">
        <location>
            <position position="61"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="covalent" evidence="8">
        <location>
            <position position="203"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="8">
        <location>
            <position position="206"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="9">
        <location>
            <position position="207"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>2</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="covalent" evidence="8">
        <location>
            <position position="328"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="8">
        <location>
            <position position="331"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="9">
        <location>
            <position position="332"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>3</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000018-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000018-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PRC94842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="426" mass="46646" checksum="B07EF70E30B404DB" modified="2018-07-18" version="1">MKRLIAAFIVTLLAFFVISAYVIGGRDTAHIYPSVNVAESAAQQIQRGSYLLKAGNCMACHTARGAAEFSGGRMLPTTFGQFYTPNITSDVKTGIGAWSPDEFWRALHDGKGRDGRLLYPAFPYTEYTKVSRADSDAMFAALQSLPAVSQVNREHELAFPFNQRSLLLFWRALYFTPQVYQADPQQSAEWNRGAYLVQGLGHCATCHTARNSLGGSVGAALAGAEIPELNWYATSLISNAESGHVDIPVDRLVQRMQSGVSEDGRVYGLMTEVVKESLQYLEASDIQAMAVYLKSQQKKDQRIESEKVTERELAVTMARGEKIYKENCVECHQANGKGAAPAYPALAGSRLVNLASTTNITRIILNGGFSPSTQHNPEPFGMPPFAQILSSQEIADVANFVRNSWGNQGSLLISSEVDRYRGQASH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4M8</accession>
    <name>A0A2S9H4M8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0086</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94891">
        <property type="protein sequence ID" value="PRC94891"/>
        <property type="gene ID" value="S2091_0086"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.1140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003795">
        <property type="entry name" value="DUF192"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038695">
        <property type="entry name" value="Saro_0823-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37953">
        <property type="entry name" value="PTHR37953"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02643">
        <property type="entry name" value="DUF192"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015623814" evidence="1">
        <location>
            <begin position="24"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="145" mass="16478" checksum="6ED722F8D764A168" modified="2018-07-18" version="1">MRTFIFRATSTLLLTLAMSPAFAQQSLPVKQLTAGMFVIQAEIASTEEQRETGLMNRKEMGQNNGMLFVFDRPAGYCMWMKNTLLPLSVAFMDNEGVILNIEEMLPQTETNHCTVKPARYALEMNAEWFKRKNIKPGTKIDVLKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4Q6</accession>
    <name>A0A2S9H4Q6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Virulence-associated protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0143</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94948">
        <property type="protein sequence ID" value="PRC94948"/>
        <property type="gene ID" value="S2091_0143"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037914">
        <property type="entry name" value="SpoVT-AbrB_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89447">
        <property type="entry name" value="SSF89447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="77" mass="8770" checksum="083F6182BFA8107F" modified="2018-07-18" version="1">MTISTVFISNRTQAVRIPLELRLPKEVTKVEVRAVGNERIIAPVGESWNSFFLNTPPVSDDFLEERATQHQADREAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4R5</accession>
    <name>A0A2S9H4R5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Response regulator containing CheY-like receiver AAA-type ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_0152</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94957">
        <property type="protein sequence ID" value="PRC94957"/>
        <property type="gene ID" value="S2091_0152"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002197">
        <property type="entry name" value="HTH_Fis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002078">
        <property type="entry name" value="Sigma_54_int"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02954">
        <property type="entry name" value="HTH_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00158">
        <property type="entry name" value="Sigma54_activat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01590">
        <property type="entry name" value="HTHFIS"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50045">
        <property type="entry name" value="SIGMA54_INTERACT_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Response regulatory" evidence="7">
        <location>
            <begin position="13"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma-54 factor interaction" evidence="6">
        <location>
            <begin position="158"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="5">
        <location>
            <position position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC94957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="470" mass="51326" checksum="D0CAF478DEDFD554" modified="2018-07-18" version="1">MQRKMPYTNPTATILIIDDDADIACAAQLLLRRRFGSIHTLTDPTGLTHLLKSVQPDVVLLDLNFTPGRIDGSEGLALLDMLQNQANPPAVITMTAYADVPLAVAALKRGATDFITKPWDNEHLIATIQAALTRRFAHEKSKQTTFASNHPQVAKSGLIGNSRAMNDLRAMLASVAPTSANVMILGENGVGKELVARAIHDASTRAGNTFLSVDMGALPESTLESELFGHRKGSFTGAQGERAGRFQAARGGTLFLDELGNMPLGAQAKLLTVLERREVTPLGADQPIAIDVRIVSATNLDEVSLYQPQVFRSDLLFRLNTIVIRVPPLRERNEDVPMLLEHYLHHYQQQYQRAARPVSVTTLSRLVNYPWPGNVRELRQACERAIILGNNTEYDFHDFGLPTASTNATTVTSTPADTETMSVDSVRLESLEREAINTALASAQGNISQASKALGISRPALYRKIEKHGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4T0</accession>
    <name>A0A2S9H4T0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="11">ClpA: ATP-dependent Clp protease ATP-binding subunit ClpA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">S2091_0081</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the ClpA/ClpB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94886">
        <property type="protein sequence ID" value="PRC94886"/>
        <property type="gene ID" value="S2091_0081"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043335">
        <property type="term" value="P:protein unfolding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1780.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019489">
        <property type="entry name" value="Clp_ATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036628">
        <property type="entry name" value="Clp_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004176">
        <property type="entry name" value="Clp_R_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013461">
        <property type="entry name" value="ClpA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001270">
        <property type="entry name" value="ClpA/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018368">
        <property type="entry name" value="ClpA/B_CS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028299">
        <property type="entry name" value="ClpA/B_CS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041546">
        <property type="entry name" value="ClpA/ClpB_AAA_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07724">
        <property type="entry name" value="AAA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17871">
        <property type="entry name" value="AAA_lid_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02861">
        <property type="entry name" value="Clp_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10431">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00300">
        <property type="entry name" value="CLPPROTEASEA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01086">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81923">
        <property type="entry name" value="SSF81923"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02639">
        <property type="entry name" value="ClpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51903">
        <property type="entry name" value="CLP_R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00870">
        <property type="entry name" value="CLPAB_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00871">
        <property type="entry name" value="CLPAB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 9" id="KW-0143">Chaperone</keyword>
    <keyword evidence="11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Clp R" evidence="10">
        <location>
            <begin position="1"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC94886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="765" mass="84010" checksum="1D6107FF7C9AC7B6" modified="2018-07-18" version="1">MIAQELEVSLHMAFVEARQARYEFITVEHLLLALLDNPSAAEVMRACAVNIEDLRKTLSNFVSDNTPTVAGTGEVDTQPTLGFQRVIQRAIMHVQSASNGKKEVTGANVLVAIFGEKDSHAVYYLHQQGVTRLDVVNFISHGVRKDNPTDAQKSPDGIEESHSEAQAKESALDQFTLNLNIAAAEGKIDPLVGRDSEVERVVQILCRRRKNNPLLVGEAGVGKTAIAEGLALRITLGDVPDILQNAVVYSLDMGSLLAGTKYRGDFELRLKAVLKQLKDAPNGILFIDEIHTIIGAGSASGGTLDASNLLKPALSSGQLKCIGATTYTEYRGVFEKDHALSRRFQKIDVIEPTIEQTVQILRGLKTRFEEHHNVKYSASALTSAAELSARFINDRHLPDKAIDVIDEAGAAQRVLPKSKQKKTIGRLEIEEIISKIARIPPQTVNQDDRSKLQTIERDLKNVVFGQDPAIDALSSAIKMARAGLGKLDKPIGSFLFSGPTGVGKTEMAKQLAFTLGIELIRFDMSEYMERHAVSRLIGAPPGYVGFDQGGLLTEAISKKPHTVLLLDEIEKAHPDVFNILLQVMDHGTLTDNNGRKADFRNVIIIMTTNAGAESLQKRSIGFTDNKEAGDEMADIKRMFTPEFRNRLDAIISFGALDEAIILRVVDKFLMQLEEQLHEKKVDAIFTDNLRQFLGKKGFDPLMGARPMARLIQDTIRKALADELLFGKLVSGGKVQVDLDENNQIKLDFSEGDARPSATQEAVEAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4T3</accession>
    <name>A0A2S9H4T3_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">TM2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_0190</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94995">
        <property type="protein sequence ID" value="PRC94995"/>
        <property type="gene ID" value="S2091_0190"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007829">
        <property type="entry name" value="TM2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05154">
        <property type="entry name" value="TM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="38"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="62"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="105"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="domain" description="TM2" evidence="6">
        <location>
            <begin position="8"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF05154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC94995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="141" mass="15262" checksum="07637066E825FBBD" modified="2018-07-18" version="1">MTTQQTSHKNKTIAALLASIGGGIGMHRFYLAGWRDKWAWLHFASLPISLLIYFFSYNVLSFFTAAPLILSVLIGFLASLVIGTTSDEKWDTQFNANSSQKSESGWPIAMILVLTLGIGAGSLIAVIARTSDLFLTGGLYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4V8</accession>
    <name>A0A2S9H4V8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Acetyl-CoA dehydrogenase C-terminal like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">S2091_0193</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94998">
        <property type="protein sequence ID" value="PRC94998"/>
        <property type="gene ID" value="S2091_0193"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016627">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025878">
        <property type="entry name" value="Acyl-CoA_dh-like_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020953">
        <property type="entry name" value="Acyl-CoA_DH_N_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12806">
        <property type="entry name" value="Acyl-CoA_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12418">
        <property type="entry name" value="AcylCoA_DH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="SSF47203"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="SSF56645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AcylCoA_DH_N" evidence="8">
        <location>
            <begin position="2"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_N" evidence="7">
        <location>
            <begin position="77"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_M" evidence="6">
        <location>
            <begin position="161"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_1" evidence="5">
        <location>
            <begin position="283"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_C" evidence="9">
        <location>
            <begin position="465"/>
            <end position="590"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF12806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC94998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="596" mass="63761" checksum="EABAD65F073CE556" modified="2018-07-18" version="1">MSYNAPLKDMLFVLNELAGLKQINALPNCEDATPDTVEAILEENAKFAGGVIAPLNWIGDQAPSSWKDGVVTTTKGFKEAFKQFAEAGWQGVQHPTEYGGQGLPKLVATPCLEMLNSASISFALCPLLTDGAIEALLTAGSDELKSQYLENLISGKWTGTMNLTEPQAGSDLAMVRSRAVPNDDGTFAVFGTKIFITYGEHDMAENIVHLVLARTPNAPEGVKGISLFLVPKFMVNADGSLGARNDVHCVSIEHKLGIKASPTAVLQFGDHGGAIGYLIGEENRGLEYMFIMMNAARFGVGMQGIGVAERAYQQAVTFAKDRIQSRDLAGSAGPVAIIHHPDVKRMLMTMRSQIEAARALAYVAAAKLDTAHHHVDAAVRKQNQIVYEYLVPIVKGWSTEMSIDVTSTGVQVHGGMGFIEETGAAQHYRDSRILTIYEGTTAIQANDLVGRKTVRDAGATAKVILAEVRATAEQLAASKQADLLAIEVQLTAAAAAMDEVVTYVANNMKTDIKAVFAGSVPYLKLAGIVLGGWQMGRAALVAAEKLQEGVADISFYQAKIATARFFAEHYLVQAQGIKTSILLGSVGTLALSEQQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4Y8</accession>
    <name>A0A2S9H4Y8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative redox protein regulator of disulfide bond formation</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0196</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sulfur carrier protein TusA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95001">
        <property type="protein sequence ID" value="PRC95001"/>
        <property type="gene ID" value="S2091_0196"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.110.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001455">
        <property type="entry name" value="TusA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036868">
        <property type="entry name" value="TusA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01206">
        <property type="entry name" value="TusA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64307">
        <property type="entry name" value="SSF64307"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01148">
        <property type="entry name" value="UPF0033"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UPF0033" evidence="2">
        <location>
            <begin position="7"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS01148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC95001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="75" mass="8627" checksum="C91193A2730C3D6F" modified="2018-07-18" version="1">MHFNKELDARGLNCPLPILKAKKALAEMLSGEILHVISTDPGSIRDFQAFSKQTGNELIAHEEHLQEYEYYIKRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H565</accession>
    <name>A0A2S9H565_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Heat-inducible transcription repressor HrcA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">hrcA</name>
        <name evidence="8" type="ORF">S2091_0302</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the HrcA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95107">
        <property type="protein sequence ID" value="PRC95107"/>
        <property type="gene ID" value="S2091_0302"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00081">
        <property type="entry name" value="HrcA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002571">
        <property type="entry name" value="HrcA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021153">
        <property type="entry name" value="HrcA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005104">
        <property type="entry name" value="WHTH_HrcA_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023120">
        <property type="entry name" value="WHTH_transcript_rep_HrcA_IDD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34824">
        <property type="entry name" value="PTHR34824"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01628">
        <property type="entry name" value="HrcA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03444">
        <property type="entry name" value="HrcA_DNA-bdg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005485">
        <property type="entry name" value="HrcA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00331">
        <property type="entry name" value="hrcA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5" id="KW-0678">Repressor</keyword>
    <keyword evidence="3 5" id="KW-0346">Stress response</keyword>
    <keyword evidence="4 5" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 5" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HrcA_DNA-bdg" evidence="7">
        <location>
            <begin position="5"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="domain" description="HrcA" evidence="6">
        <location>
            <begin position="104"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01628"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC95107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="339" mass="36966" checksum="2AE22BBECE1B84D2" modified="2018-07-18" version="1">MQLDNRAQTLLKALVERYIADGQPVGSRALSKISGLDLSPATIRNVMADLEEMGFVSSPHTSAGRIPTPRGYRVFVDTLLTVQHGDIASLESKMQALNGHNPQQKIITNAAQMLSSLSHFAGVVMTPRSESVFQQIEFLRLSEKRILLVIVAPNGDVQNRLLLTEVDYTPAQLIQAGNYINHHFAGLALTEVRQRLQGELSQLQNELSTLMKAAVQAGSDAMEDSGDEVVISGERNLLKVNELSSNMSSLRQLFDLFEQKTGLINLLDMSSRASGVQIFIGGESQLVPMDDMSVVTSTYQVNGKVVGTLGVIGPTRMAYERVIPIVDITAKLLSNALSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H579</accession>
    <name>A0A2S9H579_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0337</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95142">
        <property type="protein sequence ID" value="PRC95142"/>
        <property type="gene ID" value="S2091_0337"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015535743" evidence="1">
        <location>
            <begin position="21"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC95142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="146" mass="15508" checksum="D3FCE138431AF21C" modified="2018-07-18" version="1">MKKILAIMLVTSAVAMSAQASDTKVMLPIAGAMAANDAQARLGDSVKFYFAGQTTPAIIKTLGSDKVSLKTNAVGKSDEKSCNWVFLSDMISLQKRAVELGANAVVNITNNYNNVENPSATEFECHVGTIMSGVAFKADFVRIGDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5A5</accession>
    <name>A0A2S9H5A5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Choline dehydrogenase and related flavoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_0359</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95164">
        <property type="protein sequence ID" value="PRC95164"/>
        <property type="gene ID" value="S2091_0359"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="PTHR11552"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000137">
        <property type="entry name" value="Alcohol_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00623">
        <property type="entry name" value="GMC_OXRED_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00624">
        <property type="entry name" value="GMC_OXRED_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GMC_OxRdtase_N" evidence="3">
        <location>
            <begin position="83"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="domain" description="GMC_OxRdtase_N" evidence="4">
        <location>
            <begin position="255"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS00623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS00624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC95164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="539" mass="58497" checksum="A10C601C68BA44E3" modified="2018-07-18" version="1">MGDQEFDYVIVGAGSAGCVIASRLTENPDITVCLLEAGGSDSSVLIHAPAGVVAMVPTKINNYAYETVPQPGMNGRKGYQPRGKTLGGSSSINAMLYVRGNRWDYDHWAELGNPDWGYDDVLPYFKRAENNEQFDDAFHGQGGPLNVTYPRYESDVSAMFLRAAQESGVVLNPDYNGASQEGAFLYQVTHKNGERCSAAKGYLTPNLQRPNLKIITNAVSAKIDVIGRRATGVQFYQGNELKAVKARREVIVSAGSFGTPQLLQLSGIGNAEQLSAMGITPVVNLPGVGQNLQDHIDYVQSWIAPSNSATFGASLRGIKNVASAIGQWRRERRGMITSTFASAGAFLKSSPEIALPDLQLVFVLALVDDHARKPHLSHGISCHVDVLRPYSRGSVNLRSTDPRMAPLIDPCFLSDERDLQLLVRGGQIQQRIMESAHLAPVRQKMLYPVDVADLKEIEKDVRNRADTQYHPVGTCKMGPINDPMAVVDAQLRVHGMECLRVVDASIMPTIVGGNTNAPTIMIGEKAAAMIAASRSTKTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5C7</accession>
    <name>A0A2S9H5C7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phosphopantetheinyl transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0336</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95141">
        <property type="protein sequence ID" value="PRC95141"/>
        <property type="gene ID" value="S2091_0336"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008897">
        <property type="term" value="F:holo-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.470.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008278">
        <property type="entry name" value="4-PPantetheinyl_Trfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037143">
        <property type="entry name" value="4-PPantetheinyl_Trfase_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01648">
        <property type="entry name" value="ACPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56214">
        <property type="entry name" value="SSF56214"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ACPS" evidence="2">
        <location>
            <begin position="119"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC95141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="219" mass="24720" checksum="3F8B291B9FEF4651" modified="2018-07-18" version="1">MSESATNKIAGIATVWLIDSRTVTDEQLAPLLSWLSISEIERYKRFMRPLRQRQFLIGRLLLRCVLARTLNIAVNSIVLTEQANNAPLLHIPNLTNTPEFSLSHTGNWIACAVSLSTQLGLDIEELNTSRDLHALSQQAFSADENAWLALQADDSKVAAFYQLWSRKEAHYKLTQSHALPHNDYCYTLPHPAISIVLCTEFELGELPKLETVDWVKLLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5C9</accession>
    <name>A0A2S9H5C9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0271</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95076">
        <property type="protein sequence ID" value="PRC95076"/>
        <property type="gene ID" value="S2091_0271"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015478671" evidence="2">
        <location>
            <begin position="21"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC95076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="110" mass="12513" checksum="2F631DE93D3DF7DF" modified="2018-07-18" version="1">MKRILIIFLLTILPLQMSWASVANYCLHEQDKSVQHFGHHTHQHQTEQQPQSDGTDSDCDYCHHTGSIFALTNSLQLTDAAHPFPLALDPVLYQSHIPDSLTKPNWRGIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5D7</accession>
    <name>A0A2S9H5D7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0387</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95192">
        <property type="protein sequence ID" value="PRC95192"/>
        <property type="gene ID" value="S2091_0387"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025399">
        <property type="entry name" value="DUF4372"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002559">
        <property type="entry name" value="Transposase_11"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01609">
        <property type="entry name" value="DDE_Tnp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14294">
        <property type="entry name" value="DUF4372"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4372" evidence="2">
        <location>
            <begin position="2"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="domain" description="DDE_Tnp_1" evidence="1">
        <location>
            <begin position="120"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC95192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="264" mass="30060" checksum="222317D81E1812FC" modified="2018-07-18" version="1">MGKTLFAQVMEFVPWKNFSRIIGRHGGDAGVKTLSCADLFRIMGFSQLTWRESLRDIEVCLTANRAKLFHMGLKNIPARSTLSDALNQRDWRIYHALAQRLIIRARELYADAPMTVDLDASVYALDATTIDLCLSLFDWVPFRKAKAAIKLHTLLDLRGAIPAFIHISDGKMHEVKVLDFLPIEAGAFYIMDRGYLDFERLYNMHQAGAFFVTRAKINMNFRCIYSALVNKDMGIICDQTICLNGFYKVERIFGISASDSIQRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5H6</accession>
    <name>A0A2S9H5H6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0427</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95232">
        <property type="protein sequence ID" value="PRC95232"/>
        <property type="gene ID" value="S2091_0427"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC95232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="77" mass="8322" checksum="BB36AE3BB3F42E40" modified="2018-07-18" version="1">MQQLHFELTDEFIELNNLLKVMGLCDSGGAGKALVAQGNVRVNGQQELRKTCKIRAGQVVSIGDVRIKVASPTGLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5T9</accession>
    <name>A0A2S9H5T9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0441</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95246">
        <property type="protein sequence ID" value="PRC95246"/>
        <property type="gene ID" value="S2091_0441"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="58"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC95246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="85" mass="9334" checksum="5F2C426B0763C82D" modified="2018-07-18" version="1">MIEYFITLLLSFSMTASDAVSTVKDGLNHSAVIASDLKKVVKLNPFADFNKDVDTQSTVNINSNTPKKDNTMSGLARAQIKKQQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GS61</accession>
    <name>A0A2S9GS61_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Hemagluttinin repeat</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4734</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000057">
        <property type="protein sequence ID" value="PRC90560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90560">
        <property type="protein sequence ID" value="PRC90560"/>
        <property type="gene ID" value="S2091_4734"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043170">
        <property type="term" value="P:macromolecule metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006807">
        <property type="term" value="P:nitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044238">
        <property type="term" value="P:primary metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025157">
        <property type="entry name" value="Hemagglutinin_rpt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13332">
        <property type="entry name" value="Fil_haemagg_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC90560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="171" mass="17564" checksum="FA919B73B0BF7972" modified="2018-07-18" version="1">MEGAKLQANDIALDAANNINLLAAKNTSDLQSSNSGSSAGIGATLGSNGQQTGLSFQISVSQSKGHANGSETTYDNTQITATDKLSIKSGNDTNLIGAQLAADKVKANIGDNLNIVTLQDQSNYDSKQENGGFSLSLCIPPICAGTPVTVSINYEKQTVNHNYQSAAGKGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GS99</accession>
    <name>A0A2S9GS99_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4713</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000051">
        <property type="protein sequence ID" value="PRC90575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90575">
        <property type="protein sequence ID" value="PRC90575"/>
        <property type="gene ID" value="S2091_4713"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015593364" evidence="1">
        <location>
            <begin position="38"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="71" mass="7024" checksum="F9E3A5C65E54E0C8" modified="2018-07-18" version="1">MLYGGWVTVPINPMPLKNATCVMVPLLSVAVAVNVNAAGAVSDCAVVGLVNVITNGAAVTVKDCITGVAGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSA1</accession>
    <name>A0A2S9GSA1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000046">
        <property type="protein sequence ID" value="PRC90593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90593">
        <property type="protein sequence ID" value="PRC90593"/>
        <property type="gene ID" value="S2091_4700"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC90593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="40" mass="4157" checksum="83F9681E6E1D2F8B" modified="2018-07-18" version="1">MPGCALQPSVIGMNELFLSSLNNKKATPSVLADMSGFLSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSD5</accession>
    <name>A0A2S9GSD5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4671</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000043">
        <property type="protein sequence ID" value="PRC90620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90620">
        <property type="protein sequence ID" value="PRC90620"/>
        <property type="gene ID" value="S2091_4671"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011250">
        <property type="entry name" value="OMP/PagP_b-brl"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56925">
        <property type="entry name" value="SSF56925"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="327" mass="34446" checksum="B0070D1019111C47" modified="2018-07-18" version="1">MQSSNQLKTKRHVTTIAGLIMVGALSACGGGSGGGNDGKHIDSAKPIVPPVAPPISAATEFSRIGLDYQVGSNDYSRGDWATSIDASANITFSSTNKDSPALNYSFRFPSGLPGGAISGGLFSTTIGSANKTIQILTPSSTKTVQNVFWRNTNDPSVYGFGQAGYMVNPSKITWPTNGTSTYSGKAFQYIVSDGSIPSFAMYTNKITATVDYSAKTISIAVAPNPTLLNTIGNPLIINEAAIQNATNITMSNLNLSGSTIDLDPDPATGNWSQQHSNLGVGVASIDLAFFGNTAQELAGTLTFHNNQGMDYHIWRHQHISFALAKQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSF1</accession>
    <name>A0A2S9GSF1_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Acetyl-coenzyme A synthetase</fullName>
            <shortName evidence="5">AcCoA synthetase</shortName>
            <shortName evidence="5">Acs</shortName>
            <ecNumber evidence="5">6.2.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Acetate--CoA ligase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Acyl-activating enzyme</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">acsA</name>
        <name evidence="10" type="ORF">S2091_4635</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>acetate + ATP + CoA = acetyl-CoA + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:23176"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.2.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="PTM">
        <text evidence="5">Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.2.1.1" evidence="5"/>
    <dbReference type="EMBL" id="PUGF01000040">
        <property type="protein sequence ID" value="PRC90652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90652">
        <property type="protein sequence ID" value="PRC90652"/>
        <property type="gene ID" value="S2091_4635"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003987">
        <property type="term" value="F:acetate-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016208">
        <property type="term" value="F:AMP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019427">
        <property type="term" value="P:acetyl-CoA biosynthetic process from acetate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01123">
        <property type="entry name" value="Ac_CoA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011904">
        <property type="entry name" value="Ac_CoA_lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032387">
        <property type="entry name" value="ACAS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16177">
        <property type="entry name" value="ACAS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02188">
        <property type="entry name" value="Ac_CoA_lig_AcsA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0007">Acetylation</keyword>
    <keyword evidence="3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 5 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ACAS_N" evidence="9">
        <location>
            <begin position="38"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding" evidence="7">
        <location>
            <begin position="101"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding_C" evidence="8">
        <location>
            <begin position="549"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Coenzyme A binding" evidence="5">
        <location>
            <begin position="203"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="322"/>
        </location>
        <ligand>
            <name>CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="402"/>
            <end position="404"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="426"/>
            <end position="431"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="517"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="533"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="541"/>
        </location>
        <ligand>
            <name>CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="544"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="555"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="560"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-acetyllysine" evidence="5">
        <location>
            <position position="630"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF16177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC90652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="665" mass="72976" checksum="38F2C49607240AF7" modified="2018-07-18" version="1">MSEIESANETQTGKQESRIFPPPATFQAQANVSGMDDYRALCAAAQTDEQDFWCKLAREQLQWHKPFTQGLDESNAPFYTWFADGEMNVSYNCLDVHLTNGNADKTAIIFEADDGTSSKISYRELHQKVSKFANGLRSLGVKKGDRVIIYMPMSVEGVAAMQACARIGATHSVVFGGFSAKSLQERIIDAGAVAVITSDYQVRGGKQLPLKAIVDEAFTLGGCEGIANVVVYQRTGGQVHWSTRDIWLHELTKDQPADCEPEWVSAEHPLFILYTSGSTGKPKGVQHSSGGYLLWTKLTMQWVFDLKPTDVFWCTADIGWVTGHSYIAYGPLAAGATQIVFEGIPTFPNAGRFWSTIEKHKTTIFYTAPTAIRSLIKAADGDATIHPNKFNLTSLRLLGSVGEPINPEAWMWYYKNVGRDLCPIVDTFWQTETGGIMMSPLPGATPLVPGSCTLPLPGIASAIVDEAGHDLPNGQGGLLVVKRPWPSMIRTIWNDPERFKKSYFPEELGGNIYLAGDGAIRNKETGYFTITGRIDDVLNVSGHRMGTMEIESALVANPMVAEAAVVGRPDDTTGEAICAFVVLKRSRPTGDEARQIAIELRNWVAKEIGPIAKPKEIRFGDNLPKTRSGKIMRRLLRILAKGEVITQDVSTLENPAILEQLKEAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSI5</accession>
    <name>A0A2S9GSI5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Bacterial regulatory protein, tetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_4623</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000039">
        <property type="protein sequence ID" value="PRC90673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90673">
        <property type="protein sequence ID" value="PRC90673"/>
        <property type="gene ID" value="S2091_4623"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039538">
        <property type="entry name" value="BetI_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13977">
        <property type="entry name" value="TetR_C_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0678">Repressor</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="3">
        <location>
            <begin position="21"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="2">
        <location>
            <begin position="44"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC90673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="211" mass="23983" checksum="817DC418E790BE20" modified="2018-07-18" version="1">MSNNAPPYITTKNSVTTEKGIERMHEILHAARQLFAAEGYAGLSMRRLALTLNMSLSNVQHYYKSKDILVDAMLMYTMNIFQAKIDNIAQTMQQASRIDQFNSTIEMFLDELSDPVTHGVFFEIWALAERNVFASELMDKMIARERKTIFKLIQGLVPDISDEQAKLRAVLIVAQVEGLMLFRLHKNVPQKEVAEIHTALRKSVLNLATVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSI7</accession>
    <name>A0A2S9GSI7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4615</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000039">
        <property type="protein sequence ID" value="PRC90665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90665">
        <property type="protein sequence ID" value="PRC90665"/>
        <property type="gene ID" value="S2091_4615"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015784336" evidence="1">
        <location>
            <begin position="28"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="353" mass="37383" checksum="19FF16CECE650CB3" modified="2018-07-18" version="1">MTKLLLASSFKFITLVSSITLASNALACATCGCSLSPDGALGYATNSGWGISLDDSFINQNQLRSGTGTISAAQVQALTGQEVENQTINRYLTLGLSYSSGTDWNFKLSLPYIDRSHSTYGTDATLPLTSSQLSSASATGLGDIKLIASYQGWLPTKNLGVQVGIKLPSGNYGGASVSNTNGTVGQGSVGRNPVGFGPAGNSGSTYLDTSLNVGNGSTDLILGSYYFQPVSQNFDAFINGQYQFSMKQELNQTGADYRPGNQSNLSFGLRYEADPLIVPQLQINLTHKNADSGALADRNDTAGNVAYLSPGVTMSVMQNTRIYAFLQVPIYSNLSGYQLFPRYTASLGMSTHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSN8</accession>
    <name>A0A2S9GSN8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_4560</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000037">
        <property type="protein sequence ID" value="PRC90734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90734">
        <property type="protein sequence ID" value="PRC90734"/>
        <property type="gene ID" value="S2091_4560"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010559">
        <property type="entry name" value="Sig_transdc_His_kin_internal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06580">
        <property type="entry name" value="His_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="46"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="80"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="126"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="domain" description="His_kinase" evidence="2">
        <location>
            <begin position="171"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06580"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC90734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="361" mass="39815" checksum="EC35B6CC5ED20AF6" modified="2018-07-18" version="1">MKTNAPLSTNSWRYVALAWLALALFDATQTVVIMRAMGMHHNWLTLFSVTTASWAVWILITPVVLALLQRFRLPTKEVMPWAVHAAACMAIGALWATWGALLEHATNPLANSSGPDAFTDLWKAKFIGNLVGDVILYGAIVALSLTLEAHKRLAQQQAASARLSELLAQTQLAALRLQIEPHFIFNSLNAVTGLIREEKGSVAIAMIAALGDLLRRVTDQSERQFVALEEEIIFLRKYLDIQQMRFAERLRFQMNIPNELMKAQVPDFILQPLVENAIKHGIAKRAGGGELTVVAARDGAVLTLSVYNDGPLLPEQIREGVGVANARRRLLALYGNTQTMTLQNRANAGVLAMITLPYSEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSV4</accession>
    <name>A0A2S9GSV4_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Flagellar motor switch protein FliN</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">S2091_4533</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FliN/MopA/SpaO family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000036">
        <property type="protein sequence ID" value="PRC90785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90785">
        <property type="protein sequence ID" value="PRC90785"/>
        <property type="gene ID" value="S2091_4533"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009425">
        <property type="term" value="C:bacterial-type flagellum basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003774">
        <property type="term" value="F:cytoskeletal motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071973">
        <property type="term" value="P:bacterial-type flagellum-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.330.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012826">
        <property type="entry name" value="FliN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001543">
        <property type="entry name" value="FliN-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001172">
        <property type="entry name" value="FliN_T3SS_HrcQb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036429">
        <property type="entry name" value="SpoA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01052">
        <property type="entry name" value="FliMN_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00956">
        <property type="entry name" value="FLGMOTORFLIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101801">
        <property type="entry name" value="SSF101801"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02480">
        <property type="entry name" value="fliN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10" id="KW-0966">Cell projection</keyword>
    <keyword evidence="5" id="KW-0145">Chemotaxis</keyword>
    <keyword evidence="10" id="KW-0969">Cilium</keyword>
    <keyword evidence="6" id="KW-0283">Flagellar rotation</keyword>
    <keyword evidence="10" id="KW-0282">Flagellum</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FliMN_C" evidence="9">
        <location>
            <begin position="67"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC90785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="147" mass="15945" checksum="7C355A991325C6A4" modified="2018-07-18" version="1">MDDMNENSAPAEDSPIDEDDWGAAIAEQEKADAAAALAKPPEVQATVFQELSPKQNKLETHNDIDFILDIPVQLTVELGRTKIAIKNLLQLAQGSVVELDGMAGEPMDVLVNGCLIAQGEVVVVNDKFGIRLTDIITPAERIRKLNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GT26</accession>
    <name>A0A2S9GT26_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4451</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000034">
        <property type="protein sequence ID" value="PRC90870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90870">
        <property type="protein sequence ID" value="PRC90870"/>
        <property type="gene ID" value="S2091_4451"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008473">
        <property type="entry name" value="Phage_holin_3_7"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05449">
        <property type="entry name" value="Phage_holin_3_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="60"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="89" mass="9790" checksum="A9D0881A7320C971" modified="2018-07-18" version="1">MTKLLMLITLLSYIGTCARLLSYRRGLGNYRLKISLAAWCLILFTGTNAIDILLHPHAVSFGNAGIAVTLFLLVWRARGNVASITRSDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GT73</accession>
    <name>A0A2S9GT73_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ABC-type branched-chain amino acid transport systems periplasmic component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_4415</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000033">
        <property type="protein sequence ID" value="PRC90922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90922">
        <property type="protein sequence ID" value="PRC90922"/>
        <property type="gene ID" value="S2091_4415"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028081">
        <property type="entry name" value="Leu-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13458">
        <property type="entry name" value="Peripla_BP_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015537464" evidence="1">
        <location>
            <begin position="23"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="domain" description="Peripla_BP_6" evidence="2">
        <location>
            <begin position="27"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC90922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="403" mass="44128" checksum="455FB1C2D502DFC7" modified="2018-07-18" version="1">MRKYKLRIVWILVTMLFGVAQAEELPTIKIGIVAPVTGKSSEDMGTSIVGGAKVFLEDINQIGGILGRKVELVIRDDQAKPDRGVAVSKELVDVEKVVAVVGFGNSGVALPSSKIMQDAKIPLIISGATAAAITQSFMPPAYPTSYVFRVAPSDALQPIVMLNDLIDRRKINNIALIHDESPYGILGKRSVLEELARRKIKAVDVESFKTGDQDLTVQLQRAKDSGAQAIVMYCLHVDAAVIVKTAQKLHMNVPIVGPWTISHQTFSDNLGSSAEGVRTTVTFIENELNFRTNEFATAYKRINKVSRIPSAMAAAQTYDALRLLTLAIYKANSTDGTKIQAALENLDNRTTSTVISRYFKPFSPLDHEAISLNMILMGEIHNGKVVYAYKEDANENLIVRTKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTE3</accession>
    <name>A0A2S9GTE3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ogr/Delta-like zinc finger</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4288</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000031">
        <property type="protein sequence ID" value="PRC90992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90992">
        <property type="protein sequence ID" value="PRC90992"/>
        <property type="gene ID" value="S2091_4288"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007684">
        <property type="entry name" value="Znf_Ogr/Delta"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04606">
        <property type="entry name" value="Ogr_Delta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ogr_Delta" evidence="1">
        <location>
            <begin position="8"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="86" mass="9625" checksum="BFF125221801C00D" modified="2018-07-18" version="1">MRVISLPCPHCESRVLARKSRTLSPLFKEITYMCQNPDCGHTFVAGLEVLRTLSLSALPKTNLRIPISQHVRHNAANQLSLNLFVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTI4</accession>
    <name>A0A2S9GTI4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Prepilin-type N-terminal cleavage/methylation domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4319</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000031">
        <property type="protein sequence ID" value="PRC91023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91023">
        <property type="protein sequence ID" value="PRC91023"/>
        <property type="gene ID" value="S2091_4319"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043683">
        <property type="term" value="P:type IV pilus assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031982">
        <property type="entry name" value="PilE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16732">
        <property type="entry name" value="ComP_DUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="158" mass="16952" checksum="F0BDCA5288246582" modified="2018-07-18" version="1">MKYLSKLKFSDHVGKDRQAGFTLIELMVVIVIIGILVAVAVPAYNTSVQKSHRTDAKTALLDLASREEKFYSLNNEYSQTASDLYGSSVTAFPKAQSGTTAYYSLSVTATTTTFKAIASIITTTQQNGDPCGDFTISNTGVTANQDASENAITGLSCW</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTJ1</accession>
    <name>A0A2S9GTJ1_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 4">Regulatory protein RecX</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">recX</name>
        <name evidence="5" type="ORF">S2091_4304</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Modulates RecA activity.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the RecX family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000031">
        <property type="protein sequence ID" value="PRC91008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91008">
        <property type="protein sequence ID" value="PRC91008"/>
        <property type="gene ID" value="S2091_4304"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006282">
        <property type="term" value="P:regulation of DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01114">
        <property type="entry name" value="RecX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003783">
        <property type="entry name" value="Regulatory_RecX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33602">
        <property type="entry name" value="PTHR33602"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02631">
        <property type="entry name" value="RecX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC91008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="164" mass="18865" checksum="692225789E4246C6" modified="2018-07-18" version="1">MHQAQQKQQKLSLKNRALHYLFLREHSRLELGRKLVRFAQEEDDVEALLDFLEKAKFLSCERFSEALVRRRSESYGNSRILAELQTHGLDPLLLAQSKAELAESEVARACAVWQKKFAHTINPTEKTTPEQRAKQIRFLAQRGFSSSAIRVALRGEVDELDGMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTW4</accession>
    <name>A0A2S9GTW4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Response regulator of the LytR/AlgR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_4154</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000028">
        <property type="protein sequence ID" value="PRC91153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91153">
        <property type="protein sequence ID" value="PRC91153"/>
        <property type="gene ID" value="S2091_4154"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007492">
        <property type="entry name" value="LytTR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04397">
        <property type="entry name" value="LytTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00850">
        <property type="entry name" value="LytTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50930">
        <property type="entry name" value="HTH_LYTTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="7"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="HTH LytTR-type" evidence="3">
        <location>
            <begin position="164"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC91153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="261" mass="29220" checksum="3E54CD1E4ED8FA11" modified="2018-07-18" version="1">MTSARPTALIADDEPLLRSSLTRMLAQAWPELEIVAQARNGREAVEQYQAHKPTVCFLDVHMPGISGVEAARQIGRGVHIVFVTAYNDYAVEAFAQGALDYLVKPVDPARLADTVMRVRERLGTTQEAPDIEVLLDKLEARLQKKAAPEPLRWIKALVGQSLRMISVADIDYLRSDEKYTLIAWRGADGKAGEALIRTSLKELLDQLDGTHFIQVHRSVVVNMNMVSHVTRGENETASVYMKGRSEKLSVSRSYLHHFKQM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GU15</accession>
    <name>A0A2S9GU15_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Antibiotic biosynthesis monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4095</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000027">
        <property type="protein sequence ID" value="PRC91200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91200">
        <property type="protein sequence ID" value="PRC91200"/>
        <property type="gene ID" value="S2091_4095"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007138">
        <property type="entry name" value="ABM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03992">
        <property type="entry name" value="ABM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51725">
        <property type="entry name" value="ABM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABM" evidence="1">
        <location>
            <begin position="2"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="100" mass="11878" checksum="8BEE47554D2D292A" modified="2018-07-18" version="1">MILEVATLDVRAGQEQQFETAFCKASEIISNMNGYVSHQLQRCLENKSRYILLVNWQSLEDHTVGFRGSQEYQEWKRFLHHFYDPFPTVEHYESILENHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GU17</accession>
    <name>A0A2S9GU17_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_4117</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000027">
        <property type="protein sequence ID" value="PRC91222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91222">
        <property type="protein sequence ID" value="PRC91222"/>
        <property type="gene ID" value="S2091_4117"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008081">
        <property type="term" value="F:phosphoric diester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021800">
        <property type="entry name" value="DUF3369"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037522">
        <property type="entry name" value="HD_GYP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11849">
        <property type="entry name" value="DUF3369"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51832">
        <property type="entry name" value="HD_GYP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="31"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="domain" description="HD-GYP" evidence="3">
        <location>
            <begin position="318"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC91222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="529" mass="58031" checksum="85B756A7E4627280" modified="2018-07-18" version="1">MSQLPDDDDEGWLEDEGEVIDSTVKCVTKWRILIVDDELDVHAVTRLALKNITFKNQEIEILSAYSGAEGFEVLAREPDICMVLLDVVMEVENAGLILAQRIREELHNDLVRIILRTGQPGQAPEQKIIVDYDINDYKLKTELTAQKMFTCVISSLRAYEGLKTIEANRRGLDKILHAVNNLYQIDSLKDLASGVLTQISAILNFGTEGILCVMSSTNSKEVVPIVIATIGQSISLREQNVLPNTHPWSEAILQTFHDKKNFFSPMVDVLSIIAAHGKQFAVAFAPARPLTPLECNLLDIFCDRIAAAFDNLHMFDLLKTTQEATVIALADLAESRDATTGGHVRRVCRLTEAIAGELLDTGKLPVDIDPNFMTFVGLASILHDVGKVGIPDAILLKPGSHTPEERIIMQGHALIGETVLAHAAGAVEGVSSLSLGAEIAGGHHEHFDGNGYPRGLKGEAIPLSARIVAVVDVFDALLHARPYKKPWPLPEVITYINDRSGTQFDPDVIQALMNFLSTNKPDWIIAEGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GU54</accession>
    <name>A0A2S9GU54_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Chaperone protein HscA homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">hscA</name>
        <name evidence="7" type="ORF">S2091_4024</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the heat shock protein 70 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000026">
        <property type="protein sequence ID" value="PRC91239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91239">
        <property type="protein sequence ID" value="PRC91239"/>
        <property type="gene ID" value="S2091_4024"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd10236">
        <property type="entry name" value="HscA_like_NBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.34.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00679">
        <property type="entry name" value="HscA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018181">
        <property type="entry name" value="Heat_shock_70_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042039">
        <property type="entry name" value="HscA_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029048">
        <property type="entry name" value="HSP70_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029047">
        <property type="entry name" value="HSP70_peptide-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010236">
        <property type="entry name" value="ISC_FeS_clus_asmbl_HscA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19375">
        <property type="entry name" value="PTHR19375"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100920">
        <property type="entry name" value="SSF100920"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100934">
        <property type="entry name" value="SSF100934"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01991">
        <property type="entry name" value="HscA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00297">
        <property type="entry name" value="HSP70_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00329">
        <property type="entry name" value="HSP70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01036">
        <property type="entry name" value="HSP70_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 5" id="KW-0143">Chaperone</keyword>
    <keyword evidence="2 5 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC91239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="620" mass="66558" checksum="75059A4C28563ECA" modified="2018-07-18" version="1">MALLQISEPGMSTAPHQHRLAVGIDLGTTNSLVATVRNSVPEILSDDEGRSLLPSIVRYLANGNAHIGYKAQAAQTTDPKNTILSVKRFMGRGLKDIAYAENLPYDFLDTPGMVQIQTVAGVKSPVETSAQILATLRQRAEDSLGDELVGAVITVPAYFDDAQRQATKDAAKLAGLNVLRLLNEPTAAAIAYGLDNGSEGIYAVYDLGGGTFDVSILKMSKGVFEVLATGGDSALGGDDFDHRLLCWISEQAKLAPLSDADTRVLMVKAREVKELLSSKAETQIDVVLGSGENVHLTVTVENFAEITQHLVQKTMLPCKKALRDAGLQIDQIDGVVLVGGATRMPQIRKAVGTFFQTTPLCNLDPDKVVALGAAIQANLLAGNRASGDDWLLLDVIPLSLGIETMGGLAEKVIPRNSTIPCARAQEFTTFKDGQTALAIHVVQGERELVSACRSLARFELRGIPPMAAGAARIRITYQVDADGLLSVSARELRSNVEASITVKPSYGLEDDDITRMLQESNNTADSDMQLRALKEQQVEAQRIILATQSALESDAHLLNEAEHTTVLELLKAVENCSLIDDRVAIENAINALSAGTEEFAARRMDQSVRTALTGKKLDQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUA2</accession>
    <name>A0A2S9GUA2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Tfp pilus assembly protein PilZ</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3983</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000025">
        <property type="protein sequence ID" value="PRC91312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91312">
        <property type="protein sequence ID" value="PRC91312"/>
        <property type="gene ID" value="S2091_3983"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035438">
        <property type="term" value="F:cyclic-di-GMP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009875">
        <property type="entry name" value="PilZ_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07238">
        <property type="entry name" value="PilZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PilZ" evidence="1">
        <location>
            <begin position="27"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="133" mass="14511" checksum="D635330643333DEA" modified="2018-07-18" version="1">MLPRKNEMADIPNDAPAMTAAVRPSVLSLVIKEKAALYSAYMPFLKQGGIFVPTNKNYNLGDEIYLILTLLDDPNKYPIAGKVAWVTPSTAGNNKSQGIGVHFPGDDSGTRIKQRIEELLGSALRSTRITHTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUD1</accession>
    <name>A0A2S9GUD1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4051</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000026">
        <property type="protein sequence ID" value="PRC91266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91266">
        <property type="protein sequence ID" value="PRC91266"/>
        <property type="gene ID" value="S2091_4051"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006747">
        <property type="entry name" value="DUF599"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04654">
        <property type="entry name" value="DUF599"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="72"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="113"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="179"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="223" mass="25105" checksum="9DCB16064AB572D6" modified="2018-07-18" version="1">MDLHNLPFGIELAFVIGLSLCLVLYYWLFDHGYLGAQALRTFNQESRKRWVNAVLKQSGTEILAVQVLRNSIMSATVMATTCVLLVIAVMSLISDTDKFASHWLDAVTVQGMWRIKVASLLLFIFLSFWHFAQAIRIYGHVGYLLGMPKQAGDDSSLHAQQAISLLNTAGHMFSYGNRYFFFSLALALWWFGVLYLLIGTISITLMSWLLDRRALMVSGGIKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUD4</accession>
    <name>A0A2S9GUD4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_3991</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000025">
        <property type="protein sequence ID" value="PRC91320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91320">
        <property type="protein sequence ID" value="PRC91320"/>
        <property type="gene ID" value="S2091_3991"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="19"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="5">
        <location>
            <begin position="149"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="149"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC91320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="253" mass="28791" checksum="A08FEF13C8FFA32F" modified="2018-07-18" version="1">MNTEHLPNQTSGHTNHQAKILVVDDDIRLRELLRRYLSEQNFNVVTAEHAIAMNKLWQRERYDLLVLDLMLPGEDGLSICRRLRGIGDTTPIIMLTAKGEDIDRIIGLEMGADDYLPKPFNPRELVARINAVLRRKGSDEAPGGPSETPQSFEFGGFTLDLGTRTLKKGDENIPITTGEFSVLKVFARHARQPLSREKLMELARGREYEVYDRSLDVQISRLRKLIEPDPSNPLYIQTVWGLGYVFIPEGQPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GV02</accession>
    <name>A0A2S9GV02_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">GTP cyclohydrolase-2</fullName>
            <ecNumber evidence="5">3.5.4.25</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">GTP cyclohydrolase II</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ribA</name>
        <name evidence="7" type="ORF">S2091_3818</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>GTP + 4 H2O = 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)-pyrimidine + formate + 3 H(+) + 2 phosphate</text>
            <dbReference type="Rhea" id="RHEA:23704"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58614"/>
            <dbReference type="EC" id="3.5.4.25"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="5">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Cofactor biosynthesis; riboflavin biosynthesis; 5-amino-6-(D-ribitylamino)uracil from GTP: step 1/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the GTP cyclohydrolase II family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.25" evidence="5"/>
    <dbReference type="EMBL" id="PUGF01000022">
        <property type="protein sequence ID" value="PRC91540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91540">
        <property type="protein sequence ID" value="PRC91540"/>
        <property type="gene ID" value="S2091_3818"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00275">
        <property type="reaction ID" value="UER00400"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003935">
        <property type="term" value="F:GTP cyclohydrolase II activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00641">
        <property type="entry name" value="GTP_cyclohydro2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10990">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00179">
        <property type="entry name" value="RibA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032677">
        <property type="entry name" value="GTP_cyclohydro_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000926">
        <property type="entry name" value="RibA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036144">
        <property type="entry name" value="RibA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00925">
        <property type="entry name" value="GTP_cyclohydro2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142695">
        <property type="entry name" value="SSF142695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00505">
        <property type="entry name" value="ribA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3 5 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5" id="KW-0686">Riboflavin biosynthesis</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="GTP_cyclohydro2" evidence="6">
        <location>
            <begin position="25"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="143"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="5">
        <location>
            <position position="145"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="66"/>
            <end position="70"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="71"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="82"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="84"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="87"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="109"/>
            <end position="111"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="131"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="166"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="171"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC91540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="211" mass="23015" checksum="12F30929D45B27F9" modified="2018-07-18" version="1">MTSNKNKDLETSASINNSGVEFISSCVLPTPWAIFHLHAFFEAATGKEHLALTLGDVATGAPVLARLHSECLTGDALFSQRCDCGAQLETALKKIAHEGCGVLLYLRQEGRGIGLLNKVHAYRLQDAGADTVEANQALGFAPDMRNYQICQPMLQHLQVKAVKLMSNNPRKAAALQECGIQVTEQIPLIIKKNPHNERYLLTKAAKLGHVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GV61</accession>
    <name>A0A2S9GV61_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3662</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000021">
        <property type="protein sequence ID" value="PRC91546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91546">
        <property type="protein sequence ID" value="PRC91546"/>
        <property type="gene ID" value="S2091_3662"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009937">
        <property type="entry name" value="Phage_holin_3_6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07332">
        <property type="entry name" value="Phage_holin_3_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="72"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="129" mass="14658" checksum="A94265937487EEAE" modified="2018-07-18" version="1">MTISATINRIISTVVAMLYTRLELVTVELEEEFLRFSSYFIYALIALFCGGVAVSLLIFLVIALFWDEHRVAVLLSLIAVFSAISIYIAAWLRTQMSNKPRLLEQTIAELKKDAELLRVRESDSEQEPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GV65</accession>
    <name>A0A2S9GV65_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3717</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000021">
        <property type="protein sequence ID" value="PRC91601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91601">
        <property type="protein sequence ID" value="PRC91601"/>
        <property type="gene ID" value="S2091_3717"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="25"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="103"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="126"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="158"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="202"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="432" mass="48967" checksum="009EB9D1A281CB22" modified="2018-07-18" version="1">MSTNQRFAPKTELTITPFWRRLPGFFIYPLKTASILRIAGYALVAALTAVLPKLLGGIVNLVLIVLFLKYVFVIMERTMNGQFESETSLDADEGDVKQVFRQYGLIIILAFQIGICAALGGRNGLFISLLMGGLMMPAAIMIIAVTHSLSQALNPLRILFYIKTIGIPYLALCFFLFSLMGSSAWLQSFLHAHVTSWMVQPLMNFVSFYFMLMMYHMMGYAIYQYHQKLGVDVEVGFEQAEANLAEKKGSDPALALLSTLIADGQEQAAIDLLREAIKARWENNELHERYQKLLMAHDPSAAQHHAREFIAKMVNEKRLFKALDLCEYHLKLDREFRLQDSYQIHVLATAAKLASRPKLALDLMRQFDRRYPTHPDIPAIYFLSAQLLSEHYRKNAEAQQILQAIQRKFPDHPLAGNARDYAVVLDKMAALG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GV76</accession>
    <name>A0A2S9GV76_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Plasmid stabilization system protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3726</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000021">
        <property type="protein sequence ID" value="PRC91610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91610">
        <property type="protein sequence ID" value="PRC91610"/>
        <property type="gene ID" value="S2091_3726"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2310.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007712">
        <property type="entry name" value="RelE/ParE_toxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035093">
        <property type="entry name" value="RelE/ParE_toxin_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05016">
        <property type="entry name" value="ParE_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-1277">Toxin-antitoxin system</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="96" mass="10871" checksum="42C7941699091DF6" modified="2018-07-18" version="1">MTRIELATEVGADIDRILAHLVEYNVENPPARIQEIIQAISVLEYNPLIGRTVNSNNRELVIGRRSHGHVALYRYLAEIDTVFVLALRSQKEAGYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVM4</accession>
    <name>A0A2S9GVM4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3530</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000019">
        <property type="protein sequence ID" value="PRC91775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91775">
        <property type="protein sequence ID" value="PRC91775"/>
        <property type="gene ID" value="S2091_3530"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="94" mass="10734" checksum="7D1A8BB52630BD67" modified="2018-07-18" version="1">MYLDHPTISAIHSDTEPDRLERLNRVYGYVIGQADISDNKACIAKIANLHDDKGTLYVSWSSQPTDQERTFFARAWRSQIGDESTNIVHQLILD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVS1</accession>
    <name>A0A2S9GVS1_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Flagellar P-ring protein</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Basal body P-ring protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">flgI</name>
        <name evidence="5" type="ORF">S2091_3379</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 4">Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 4">Bacterial flagellum basal body</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the FlgI family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000018">
        <property type="protein sequence ID" value="PRC91823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91823">
        <property type="protein sequence ID" value="PRC91823"/>
        <property type="gene ID" value="S2091_3379"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009428">
        <property type="term" value="C:bacterial-type flagellum basal body, distal rod, P ring"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030288">
        <property type="term" value="C:outer membrane-bounded periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071973">
        <property type="term" value="P:bacterial-type flagellum-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00416">
        <property type="entry name" value="FlgI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001782">
        <property type="entry name" value="Flag_FlgI"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30381">
        <property type="entry name" value="PTHR30381"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02119">
        <property type="entry name" value="FlgI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01010">
        <property type="entry name" value="FLGPRINGFLGI"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0975">Bacterial flagellum</keyword>
    <keyword evidence="5" id="KW-0966">Cell projection</keyword>
    <keyword evidence="5" id="KW-0969">Cilium</keyword>
    <keyword evidence="5" id="KW-0282">Flagellum</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC91823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="367" mass="38110" checksum="22DB7C8A3C8FB8C5" modified="2018-07-18" version="1">MKLPAQFWMLILLIFISGETHAERIKDLASIRGVRENQLIGYGLVAGLDGSGDQTTQTPFTTQSIISMMQQLGVSLPPGTSLQLKNIAAVMVTASLPAFAQPGQLLDVTVSSMGNAKSLSGGTLLMTPLKGADNKVYAMAQGNVLVGGVGAAAAGSKAQINHLSVGRISAGATVERAVPSTLGSGEMIHLELNTSDFSTATRIVNVLNQRFGAETAMALDSRVIKVRAPIDADSRVAFIGDLESLDVNPAQMAAKVILNARTGSIVMNQAVTLDSCAVAHGNLQVIINAESKVSQPNALAAGKTEVTEKADIEIKKEPGLVVLVKAGVSLAEVVKALNSIGATPQDLLAILQAMKVSGALRAELEII</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GW06</accession>
    <name>A0A2S9GW06_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peptidyl-prolyl cis-trans isomerase</fullName>
            <shortName evidence="5">PPIase</shortName>
            <ecNumber evidence="5">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_3446</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 5">PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the cyclophilin-type PPIase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="5"/>
    <dbReference type="EMBL" id="PUGF01000018">
        <property type="protein sequence ID" value="PRC91890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91890">
        <property type="protein sequence ID" value="PRC91890"/>
        <property type="gene ID" value="S2091_3446"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000413">
        <property type="term" value="P:protein peptidyl-prolyl isomerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024936">
        <property type="entry name" value="Cyclophilin-type_PPIase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020892">
        <property type="entry name" value="Cyclophilin-type_PPIase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044665">
        <property type="entry name" value="E_coli_cyclophilin_A-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43246">
        <property type="entry name" value="PTHR43246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001467">
        <property type="entry name" value="Peptidylpro_ismrse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="SSF50891"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00170">
        <property type="entry name" value="CSA_PPIASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="6">
        <location>
            <begin position="7"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC91890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="162" mass="17803" checksum="2CBE6920187BA450" modified="2018-07-18" version="1">MAVLLTTNHGNIKIELDAEKAPKTVANFLAYVADDFYTNTIFHRVIDGFMIQGGGFEPGMKQKATNDQIENEAKNGLKNVKYSLAMARTSDPHSASAQFFINLTNNSFLDFPGQDGWGYCVFGSVIEGMDVVDKIKSVKTTRSGMFQDVPAEDVVIIKAEVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GW40</accession>
    <name>A0A2S9GW40_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_3281</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPF0126 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000017">
        <property type="protein sequence ID" value="PRC91939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91939">
        <property type="protein sequence ID" value="PRC91939"/>
        <property type="gene ID" value="S2091_3281"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005115">
        <property type="entry name" value="Gly_transporter"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03458">
        <property type="entry name" value="Gly_transporter"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="38"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="71"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="127"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="152"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="184"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="domain" description="Gly_transporter" evidence="8">
        <location>
            <begin position="14"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="domain" description="Gly_transporter" evidence="8">
        <location>
            <begin position="101"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF03458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC91939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="208" mass="21767" checksum="45B71CD1ADB5F546" modified="2018-07-18" version="1">MARMKLKTEAVVLAADLIGTSVFAVEGALSAIHGNLDLLGVMVIAFIAALGGGVIRDMLIGATPPNAIRDWRYPALTFLAGLLTFIFHSSFQAIPTQLMLVLDAAGLSLFAVAGVEKATMFGIRPFVAMLLGTVTGVGGGVIRDILMTRVPAVLQTDIYATAAFFGAFIVLLGRRFGLSEGSAGLLGGLVCFTVRLLSVAYGWHLPKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GW43</accession>
    <name>A0A2S9GW43_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Phage integrase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_3276</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000017">
        <property type="protein sequence ID" value="PRC91934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91934">
        <property type="protein sequence ID" value="PRC91934"/>
        <property type="gene ID" value="S2091_3276"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002104">
        <property type="entry name" value="Integrase_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010998">
        <property type="entry name" value="Integrase_recombinase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00589">
        <property type="entry name" value="Phage_integrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51898">
        <property type="entry name" value="TYR_RECOMBINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyr recombinase" evidence="3">
        <location>
            <begin position="166"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC91934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="333" mass="37510" checksum="3E1AB4A1463CEB12" modified="2018-07-18" version="1">MQRERKDGNPLNLPARCHYKHNAFWYIHALTGKWENLGTDIHHARHLAVHYNNDTPANHTMAWIIDDYLLHFEQLVKLKQKAARTLSDYQHYALPLKAHFGALNPEMIDAEQVKNYLDINQQLGRGVRANREKTLLGSVFAWLISTGGGNITVNPCTKIGGNKETPRVRYVSDLDYLAIYQLATPQVQLAMQLAYKTLQNPAEVLRIQRDAIQTDQGVHFIHLIHSKTNKALKIEIDKQLQQAIDNVLPATSTQHYLLASRLGTPYTPTGIAAMLHRYQKNGGIASFGLQDLKVKGALDLAQSGIAIETICDLLGHKSLAVTENFLKHHLNEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GW87</accession>
    <name>A0A2S9GW87_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">ATP synthase subunit c</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">ATP synthase F(0) sector subunit c</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">F-type ATPase subunit c</fullName>
            <shortName evidence="11">F-ATPase subunit c</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Lipid-binding protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">atpE</name>
        <name evidence="13" type="ORF">S2091_3268</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.</text>
    </comment>
    <comment type="function">
        <text evidence="11">Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cell membrane</location>
            <topology evidence="11">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the ATPase C chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000017">
        <property type="protein sequence ID" value="PRC91926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91926">
        <property type="protein sequence ID" value="PRC91926"/>
        <property type="gene ID" value="S2091_3268"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045263">
        <property type="term" value="C:proton-transporting ATP synthase complex, coupling factor F(o)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.610">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01396">
        <property type="entry name" value="ATP_synth_c_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017708">
        <property type="entry name" value="Alt_ATP_synth_F0_Csu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005953">
        <property type="entry name" value="ATP_synth_csu_bac/chlpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000454">
        <property type="entry name" value="ATP_synth_F0_csu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002379">
        <property type="entry name" value="ATPase_proteolipid_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035921">
        <property type="entry name" value="F/V-ATP_Csub_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10031">
        <property type="entry name" value="PTHR10031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00137">
        <property type="entry name" value="ATP-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00124">
        <property type="entry name" value="ATPASEC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81333">
        <property type="entry name" value="SSF81333"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03322">
        <property type="entry name" value="alt_F1F0_F0_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01260">
        <property type="entry name" value="ATP_synt_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 11" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="11" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3 11" id="KW-0138">CF(0)</keyword>
    <keyword evidence="5 11" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="7 11" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 11" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="11" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="55"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-synt_C" evidence="12">
        <location>
            <begin position="14"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="site" description="Reversibly protonated during proton transport" evidence="11">
        <location>
            <position position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PRC91926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="93" mass="9700" checksum="920B78A59D25048D" modified="2018-07-18" version="1">MDNMTIIAIVSIFTAGITIAIGVIGPALGEGRAVATALTSLAQQPDAAATITRTLFVGLAMIESTAIYCFVVSMILIFANPFWNHVISLTTGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWA1</accession>
    <name>A0A2S9GWA1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Oxidoreductase FAD-binding domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_3332</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000017">
        <property type="protein sequence ID" value="PRC91990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91990">
        <property type="protein sequence ID" value="PRC91990"/>
        <property type="gene ID" value="S2091_3332"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00207">
        <property type="entry name" value="fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006058">
        <property type="entry name" value="2Fe2S_fd_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008333">
        <property type="entry name" value="Cbr1-like_FAD-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001709">
        <property type="entry name" value="Flavoprot_Pyr_Nucl_cyt_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00970">
        <property type="entry name" value="FAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00111">
        <property type="entry name" value="Fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00371">
        <property type="entry name" value="FPNCR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="SSF52343"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="SSF54292"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="SSF63380"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00197">
        <property type="entry name" value="2FE2S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding FR-type" evidence="6">
        <location>
            <begin position="19"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="5">
        <location>
            <begin position="297"/>
            <end position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC91990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="381" mass="41778" checksum="7723B4B7E92E3FCE" modified="2018-07-18" version="1">MLISLTHQFNAAPVLWNGDSDDTLICREIRQETADVKTFVLGSPQPRLFRYAPGQFITLELDIAGQTINRCYTLSSTPTRPDQVSITVKRVPGGIVSNWLHDNLTVGSNLRVLGPAGEFSCFLHPMPPKQKYLFLSAGSGITPLMSMARAAHDLVLDANIVFMHSARTPGDIIFARELELMAFNRPQFQLGLVCERRGNQPMWAGFNGFLTHAILHNVAPDFMDRHVYTCGPAPYMAAVRALLQTAGFTMANYHEESFSFETLQADQADIGALLNLPELAQSETAIALTSHVSTSQFNIEFTRTGYQVACSADQTILSAARAAGLRLPTSCTQGLCGTCKTKMVSGQVEMKHAGGIRQREIDQGWILPCCSKPLSDVVLEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWC6</accession>
    <name>A0A2S9GWC6_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Small ribosomal subunit biogenesis GTPase RsgA</fullName>
            <ecNumber evidence="3">3.6.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rsgA</name>
        <name evidence="6" type="ORF">S2091_3365</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="3">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.-" evidence="3"/>
    <dbReference type="EMBL" id="PUGF01000017">
        <property type="protein sequence ID" value="PRC92023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92023">
        <property type="protein sequence ID" value="PRC92023"/>
        <property type="gene ID" value="S2091_3365"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042274">
        <property type="term" value="P:ribosomal small subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01854">
        <property type="entry name" value="YjeQ_EngC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01820">
        <property type="entry name" value="GTPase_RsgA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030378">
        <property type="entry name" value="G_CP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004881">
        <property type="entry name" value="Ribosome_biogen_GTPase_RsgA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010914">
        <property type="entry name" value="RsgA_GTPase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32120">
        <property type="entry name" value="PTHR32120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03193">
        <property type="entry name" value="RsgA_GTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00157">
        <property type="entry name" value="TIGR00157"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50936">
        <property type="entry name" value="ENGC_GTPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51721">
        <property type="entry name" value="G_CP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CP-type G" evidence="5">
        <location>
            <begin position="66"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="domain" description="ENGC_GTPASE" evidence="4">
        <location>
            <begin position="77"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="116"/>
            <end position="119"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="170"/>
            <end position="178"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="252"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="257"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="259"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="265"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC92023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="298" mass="33099" checksum="79510FE86CDCFC0E" modified="2018-07-18" version="1">MSKLFGTVMAAHGRHYLVEAEEMLFNCVTRGKKSDVAVGDVVEYKLTSKNQGVIEAITERKTLLYRSDQYRSKLLAANLSQLFIVVATEPGFSDDLICRALVAAEAGGIKPHLVLNKIDVLDLLPAAKKRLEIYQKLDYPVHFVSAKTNPQQTLDILMPLLEGQSTILIGQSGMGKSSLINLLIPDAAIATREISAALNTGKHTTTFVRSYHLNERSIIIDSPGFQEFGLHHLSEGMLERAFPEFRPHLGQCKFYNCHHHTEPGCAVLAAIKTGEISKMRHDMYEQLVHEAAQTLGYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWD2</accession>
    <name>A0A2S9GWD2_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Putative pterin-4-alpha-carbinolamine dehydratase</fullName>
            <shortName evidence="4">PHS</shortName>
            <ecNumber evidence="4">4.2.1.96</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">4-alpha-hydroxy-tetrahydropterin dehydratase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Pterin carbinolamine dehydratase</fullName>
            <shortName evidence="4">PCD</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_3366</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 4">
            <text>(4aS,6R)-4a-hydroxy-L-erythro-5,6,7,8-tetrahydrobiopterin = (6R)-L-erythro-6,7-dihydrobiopterin + H2O</text>
            <dbReference type="Rhea" id="RHEA:11920"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15642"/>
            <dbReference type="ChEBI" id="CHEBI:43120"/>
            <dbReference type="EC" id="4.2.1.96"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the pterin-4-alpha-carbinolamine dehydratase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.96" evidence="4"/>
    <dbReference type="EMBL" id="PUGF01000017">
        <property type="protein sequence ID" value="PRC92024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92024">
        <property type="protein sequence ID" value="PRC92024"/>
        <property type="gene ID" value="S2091_3366"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008124">
        <property type="term" value="F:4-alpha-hydroxytetrahydrobiopterin dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006729">
        <property type="term" value="P:tetrahydrobiopterin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00434">
        <property type="entry name" value="Pterin_4_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036428">
        <property type="entry name" value="PCD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001533">
        <property type="entry name" value="Pterin_deHydtase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12599">
        <property type="entry name" value="PTHR12599"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01329">
        <property type="entry name" value="Pterin_4a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55248">
        <property type="entry name" value="SSF55248"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC92024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="116" mass="13004" checksum="F020BE1F4E1D103F" modified="2018-07-18" version="1">MPSTRELLARKCQHTETALADTELAAYLAAVPGWEAAGNRIVKTYKFKNYYETLAFMNAIAYVIHVEDHHPEITLTYQQCVIKFDTHSVNGGRGGLSENDFICAAKVETVFQQSFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWF3</accession>
    <name>A0A2S9GWF3_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptide methionine sulfoxide reductase MsrA</fullName>
            <shortName evidence="4">Protein-methionine-S-oxide reductase</shortName>
            <ecNumber evidence="4">1.8.4.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Peptide-methionine (S)-S-oxide reductase</fullName>
            <shortName evidence="4">Peptide Met(O) reductase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">msrA</name>
        <name evidence="7" type="ORF">S2091_3175</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 4">
            <text>[thioredoxin]-disulfide + H2O + L-methionine = [thioredoxin]-dithiol + L-methionine (S)-S-oxide</text>
            <dbReference type="Rhea" id="RHEA:19993"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:58772"/>
            <dbReference type="EC" id="1.8.4.11"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 4">
            <text>[thioredoxin]-disulfide + H2O + L-methionyl-[protein] = [thioredoxin]-dithiol + L-methionyl-(S)-S-oxide-[protein]</text>
            <dbReference type="Rhea" id="RHEA:14217"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="Rhea" id="RHEA-COMP:12313"/>
            <dbReference type="Rhea" id="RHEA-COMP:12315"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16044"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:44120"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="EC" id="1.8.4.11"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the MsrA Met sulfoxide reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.8.4.11" evidence="4"/>
    <dbReference type="EMBL" id="PUGF01000016">
        <property type="protein sequence ID" value="PRC92040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92040">
        <property type="protein sequence ID" value="PRC92040"/>
        <property type="gene ID" value="S2091_3175"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033744">
        <property type="term" value="F:L-methionine:thioredoxin-disulfide S-oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008113">
        <property type="term" value="F:peptide-methionine (S)-S-oxide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1060.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01401">
        <property type="entry name" value="MsrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002569">
        <property type="entry name" value="Met_Sox_Rdtase_MsrA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036509">
        <property type="entry name" value="Met_Sox_Rdtase_MsrA_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01625">
        <property type="entry name" value="PMSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55068">
        <property type="entry name" value="SSF55068"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00401">
        <property type="entry name" value="msrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015727827" description="Peptide methionine sulfoxide reductase MsrA" evidence="5">
        <location>
            <begin position="28"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="domain" description="PMSR" evidence="6">
        <location>
            <begin position="50"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01625"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC92040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="235" mass="25748" checksum="7F226208BB8CBDD3" modified="2018-07-18" version="1">MKFPNSLLTSRSVIALLFCLTAVACNAAEAPTVIAAPEFDSPKTKGPLQTAVFAGGCFWGVQGVFEHVRGVRKAVSGYAGGSKATAQYDTVSSGRTGHAESVQITFDPAEISYGELLHIFFSVAHDPTQLNRQGPDSGTQYRSAIFYTDEAQKKVAQTYITQLIKSHAYQHDIVTAVSASEGFYPAEDYHQDFLIHNPTYPYIVYNDLPKINNLKHIFPDYYRGQPVLVNNSAST</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWH8</accession>
    <name>A0A2S9GWH8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Barstar (Barnase inhibitor)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3205</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the barstar family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000016">
        <property type="protein sequence ID" value="PRC92070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92070">
        <property type="protein sequence ID" value="PRC92070"/>
        <property type="gene ID" value="S2091_3205"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.370.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000468">
        <property type="entry name" value="Barstar"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035905">
        <property type="entry name" value="Barstar-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01337">
        <property type="entry name" value="Barstar"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52038">
        <property type="entry name" value="SSF52038"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Barstar" evidence="2">
        <location>
            <begin position="38"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="132" mass="15022" checksum="0D0E28DC3679DE9A" modified="2018-07-18" version="1">MNLLSTVRVNSVQSIRAFRVVDLQAAAAELGQHFLIANCAPATTKQQVLAEIAQGFYFPEHFGENFDALYDCLTSLVHKAGAQPGFVVVLEQIPNTPEFDKEARETLLDVFRDASDFWEKKKVPFRLFYYYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWJ6</accession>
    <name>A0A2S9GWJ6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3230</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000016">
        <property type="protein sequence ID" value="PRC92095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92095">
        <property type="protein sequence ID" value="PRC92095"/>
        <property type="gene ID" value="S2091_3230"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="76"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="99"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="142"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="170"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="201"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="239"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="326"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="352"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="376"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="418"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="452"/>
            <end position="477"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="570" mass="64062" checksum="6231E71E77CB3D35" modified="2018-07-18" version="1">MKPVRLPASATLALPRIGLFALCLLYILPGLIGRDPWKIGGDATSFGIMWTMAHGSWQDWLWPHIVGLPMPEEGPLSFWIGALCIKLFGWLIGDDAAARFSSVLFFALGAASVWYATYVLGRRQEAQPLQLAFGGQPEPQDFGRTLADGALLIYLGSLGLLIQSHLTGPVALQISLVAFVLYIAIRLFDIDAERPASAGKYALILGIALGLLILTRGWLIPLTLWTTCLLLAGFRYKRLLTYLALITFPAALAVTSIWLLSCKFALPFNSSPYAAWMQWNKQEFFRPSYTSLHYFIKYSAWFTWPAWPFASWAVYAWRKQTAALHIALPLSFLLALVALAFCSPYAEQSSLIPLIPPLAILAAFGLPTMKRGAINAVDWFSVIVFSMFALFIWLSWIAMQTGWPEQLHHNVFKTVPGFTAQLNPLAFIIALISTGAWLKLVHWRISRSPKVLWRAVVLSSSGVILCWLLSMTLWMPWIDYRVSYQPLAKEIAAHLPPQYNCVDTNINPAQRASFAYFGNIHFADFNLQKCDYFLAHRHAPKPLNYPDSEAIWEGHRAADKSERFMLFKNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWK0</accession>
    <name>A0A2S9GWK0_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Chaperone protein HtpG</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Heat shock protein HtpG</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">High temperature protein G</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">htpG</name>
        <name evidence="8" type="ORF">S2091_3171</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Molecular chaperone. Has ATPase activity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the heat shock protein 90 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000016">
        <property type="protein sequence ID" value="PRC92036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92036">
        <property type="protein sequence ID" value="PRC92036"/>
        <property type="gene ID" value="S2091_3171"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00505">
        <property type="entry name" value="HSP90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019805">
        <property type="entry name" value="Heat_shock_protein_90_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037196">
        <property type="entry name" value="HSP90_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001404">
        <property type="entry name" value="Hsp90_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020575">
        <property type="entry name" value="Hsp90_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11528">
        <property type="entry name" value="PTHR11528"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00183">
        <property type="entry name" value="HSP90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002583">
        <property type="entry name" value="Hsp90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00775">
        <property type="entry name" value="HEATSHOCK90"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110942">
        <property type="entry name" value="SSF110942"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00298">
        <property type="entry name" value="HSP90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 6" id="KW-0143">Chaperone</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="HATPase_c" evidence="7">
        <location>
            <begin position="29"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="A; substrate-binding" evidence="6">
        <location>
            <begin position="1"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="region of interest" description="C" evidence="6">
        <location>
            <begin position="562"/>
            <end position="635"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC92036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="635" mass="71770" checksum="1DAFA64C8311B724" modified="2018-07-18" version="1">MAGHEKQTLGFQAEVTQLLQLMIHSLYSNKEIFLRELISNASDAADKLRFEAMNNASLFENDSDLRIKVTFNKEARTITISDNGIGMSRDDAITHLGTIAKSGTKEFFGKLSGDQQKDAAMIGQFGVGFYSGFIVADKITVETRRAGSTEAVRWESAGAGDFSIEDIEKTSRGTDITLHLREGEEEFLSSWKLKSVIRTYSDHISLPILMQKEEWDEEKKEQVIKDEFETVNQASALWARSKSEITQEQYDEFYKHVSHDFQAPLTYTHNRVEGRSEYTQLLYIPARAPFDLWDRNKRGGIKLYVKRVFIMDDAEQLMPVYLRFVKGVIDSADLPLNVSREILQESRDIKFIREGSTKRVLGMLEELANADEQEKKDQYQTFWNEFGQVLKEGTGEDAGNKDRVAKLLRFSSTHNDSEAQTVSFADYLARAKEGQDKIYYVTAESFAAAKNSPHLEIFRKKGVEVLLLTDRVDEWMLSFLADFEGKELTSVAKGSLDLGSLEDEAEKKQHEQTQTDYVDLVGKMKTALEGKAKDVRVTFRLTDSPACLVADENELSGNLARMLKAAGQAAPDSKPILEINPDHPLVQRLKYETAKFDDWAHILFDQAMLAEGGNLNDPSAYVKRLNEMLLGMAGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWN8</accession>
    <name>A0A2S9GWN8_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">50S ribosomal protein L28</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpmB</name>
        <name evidence="6" type="ORF">S2091_3211</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the bacterial ribosomal protein bL28 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000016">
        <property type="protein sequence ID" value="PRC92076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92076">
        <property type="protein sequence ID" value="PRC92076"/>
        <property type="gene ID" value="S2091_3211"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.170.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00373">
        <property type="entry name" value="Ribosomal_L28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034704">
        <property type="entry name" value="L28p-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026569">
        <property type="entry name" value="Ribo_L28/L24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037147">
        <property type="entry name" value="Ribo_L28/L24_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001383">
        <property type="entry name" value="Ribosomal_L28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13528">
        <property type="entry name" value="PTHR13528"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00830">
        <property type="entry name" value="Ribosomal_L28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143800">
        <property type="entry name" value="SSF143800"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00009">
        <property type="entry name" value="L28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00373"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC92076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="78" mass="8891" checksum="E88CED83F73C66AF" modified="2018-07-18" version="1">MARVCQVTGKKPMVGNNVSHANNKTKRRFLPNLQNRRFFVESENRWVSLRLSNAGLRIIDKIGIDAVLSDLRARGEKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWX7</accession>
    <name>A0A2S9GWX7_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Molybdopterin molybdenumtransferase</fullName>
            <ecNumber evidence="7">2.10.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_3143</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 7">Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>adenylyl-molybdopterin + H(+) + molybdate = AMP + H2O + Mo-molybdopterin</text>
            <dbReference type="Rhea" id="RHEA:35047"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:36264"/>
            <dbReference type="ChEBI" id="CHEBI:62727"/>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.10.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 7">Cofactor biosynthesis; molybdopterin biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 7">Belongs to the MoeA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.10.1.1" evidence="7"/>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92227">
        <property type="protein sequence ID" value="PRC92227"/>
        <property type="gene ID" value="S2091_3143"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00344"/>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061599">
        <property type="term" value="F:molybdopterin molybdotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006777">
        <property type="term" value="P:Mo-molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032324">
        <property type="term" value="P:molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00887">
        <property type="entry name" value="MoeA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.340.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.980.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036425">
        <property type="entry name" value="MoaB/Mog-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001453">
        <property type="entry name" value="MoaB/Mog_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038987">
        <property type="entry name" value="MoeA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005111">
        <property type="entry name" value="MoeA_C_domain_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036688">
        <property type="entry name" value="MoeA_C_domain_IV_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005110">
        <property type="entry name" value="MoeA_linker/N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036135">
        <property type="entry name" value="MoeA_linker/N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10192">
        <property type="entry name" value="PTHR10192"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00994">
        <property type="entry name" value="MoCF_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03454">
        <property type="entry name" value="MoeA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03453">
        <property type="entry name" value="MoeA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00852">
        <property type="entry name" value="MoCF_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53218">
        <property type="entry name" value="SSF53218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63867">
        <property type="entry name" value="SSF63867"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63882">
        <property type="entry name" value="SSF63882"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00177">
        <property type="entry name" value="molyb_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 7" id="KW-0500">Molybdenum</keyword>
    <keyword evidence="6 7" id="KW-0501">Molybdenum cofactor biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="MoCF_biosynth" evidence="8">
        <location>
            <begin position="187"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC92227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="417" mass="44456" checksum="282BB08B642C8954" modified="2018-07-18" version="1">MSKTSQPSTVNLSVSQAQQQIQAAMQPIADAQQISLRSALDRIASSDIIAPMNVPAFDNSAMDGYAFCAQDLALNTQLNLVGSALAGHPYQASLQVGQAIRITTGAKIPERCDTVIPQELAVLIDANTLDMRNIVVRAGEHKRNCGEDLRMGEIAITKGCRLGPAQLGLLASLGIAEVSVQRRLRVAIFSTGDELRSIDQALDGSSVYDSNRVTLHAMLTRFGAEVIDLGVLADNPAELESALLNIAPQVDAIITSGGVASGAADYTKQVMQTLGEITFWAINMRPGRPFAFGKIAGKLKDTYLFGLPGNPVAVMVSFYFFVRPALQKLSGAPISNIPQINAIASQPISKKMGRTEFQRGICKVNPQGQLEVSITEKQGSGILSSMSQANCMVVLNETQADIQAGDTVKLVLFEGLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GX15</accession>
    <name>A0A2S9GX15_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glycosyl transferase family 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_2924</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92265">
        <property type="protein sequence ID" value="PRC92265"/>
        <property type="gene ID" value="S2091_2924"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="233"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="266"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_trans_2-like" evidence="3">
        <location>
            <begin position="6"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC92265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="314" mass="35259" checksum="974065EDA38281BA" modified="2018-07-18" version="1">MKPELSVVIPIYNEQAGLAQLFARLYPALDKLATEGVSYEVVFVNDGSRDQSAAILSDQFRARPDVTRVVLFNGNYGQHMAILAGFQAVRGEIVVTLDADLQNPPEEIGALVNKMREGYDYVGSIRRKRQDSLWRTWASKAMNNFRESITHIKITDQGNMLRAYGRNVIDLINQCSEMNTFVPALAYTFSRNPTEIIVEHEERAAGESKYSIYSLIRLNFDLMTGFSIMPLQLFSMLGMALSVGSGGLVVLLLIRRFLLGSEAEGLFTLFAISFFMMGVILFGIGLLGEYIGRIYQQVRGRPRFVVQTILEQND</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GX16</accession>
    <name>A0A2S9GX16_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative pyridoxal phosphate-dependent enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_2923</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the DegT/DnrJ/EryC1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92264">
        <property type="protein sequence ID" value="PRC92264"/>
        <property type="gene ID" value="S2091_2923"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00616">
        <property type="entry name" value="AHBA_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000653">
        <property type="entry name" value="DegT/StrS_aminotransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30244">
        <property type="entry name" value="PTHR30244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01041">
        <property type="entry name" value="DegT_DnrJ_EryC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000390">
        <property type="entry name" value="PLP_StrS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="188"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="2">
        <location>
            <position position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR000390-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000390-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC92264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="380" mass="41542" checksum="E3550A9AA3E6287F" modified="2018-07-18" version="1">MNTATTAPFLPFSRPSIDEATIAEVANVLRSGWLTSGPKVQAFEAALSEYLGGRIVRTFNSGTCTMEIALRIAGIGVGDEVITTPISWVATANVIIEVGATPVFADIDPITRNLDLDKLEAAITPRTKAIIPVYLSGLPMDMDRMYAIAKKYNLRVIEDAAQALGSRWKGKPIGSFGDFVSFSFQANKNLTTSEGGCLVVNTPEEARLAEKYRLQGVTRSGVDGIDVDVLGGKYNMTDIAATLGLGQLPQIDAIAAHRRSLAQHYFACFGADFEAKSGAQLPVADMENSNWHLFQIILPKTVVRADFMKQMMEFNVGTGYHYSPIHLFTMYRERGFKEGMFPVAEHIGYQTVTLPMFNAMQKEDVERAVAAVKSCLYSAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GX24</accession>
    <name>A0A2S9GX24_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2934</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92275">
        <property type="protein sequence ID" value="PRC92275"/>
        <property type="gene ID" value="S2091_2934"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009858">
        <property type="entry name" value="DUF1415"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07209">
        <property type="entry name" value="DUF1415"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="187" mass="21279" checksum="F3112CF19B3FA893" modified="2018-07-18" version="1">MTSLSHPEILSATQTWLEKAVIGLNLCPFAKAVHVKQQVRYAVSDATSARDLHSELLREIKFLLDADPTEVETTLLIHPNVLTDFLDFNDFLDVADALLEELNADGVLQIASFHPDYQFAGTKPEDIENYTNRSPYPTLHILREESVDRAVESYPDMDEIFQKNMDTLNKLGIEGWRKLFDEMEPGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GX34</accession>
    <name>A0A2S9GX34_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5 6">50S ribosomal protein L20</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rplT</name>
        <name evidence="7" type="ORF">S2091_2946</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 6">Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the bacterial ribosomal protein bL20 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92287">
        <property type="protein sequence ID" value="PRC92287"/>
        <property type="gene ID" value="S2091_2946"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000027">
        <property type="term" value="P:ribosomal large subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07026">
        <property type="entry name" value="Ribosomal_L20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1900.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00382">
        <property type="entry name" value="Ribosomal_L20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005813">
        <property type="entry name" value="Ribosomal_L20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035566">
        <property type="entry name" value="Ribosomal_protein_L20_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10986">
        <property type="entry name" value="PTHR10986"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00453">
        <property type="entry name" value="Ribosomal_L20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00062">
        <property type="entry name" value="RIBOSOMALL20"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74731">
        <property type="entry name" value="SSF74731"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01032">
        <property type="entry name" value="rplT_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00937">
        <property type="entry name" value="RIBOSOMAL_L20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5 6" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC92287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="119" mass="13474" checksum="2DAAE517481174E0" modified="2018-07-18" version="1">MPRVKRGVTARARHKKVLNLAKGYRGRRSKVYRIAKQAVMRAGQYAYRDRRNKKRVFRALWITRINAASRSHGLTYSVFMNGLKKASIGLDRKVLADMAVMDKPAFAAIVNQVKATLAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXD5</accession>
    <name>A0A2S9GXD5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">SnoaL-like domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3029</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92370">
        <property type="protein sequence ID" value="PRC92370"/>
        <property type="gene ID" value="S2091_3029"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030638">
        <property type="term" value="P:polyketide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009959">
        <property type="entry name" value="Cyclase_SnoaL-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07366">
        <property type="entry name" value="SnoaL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="126" mass="14402" checksum="9F79EA20F260D2DA" modified="2018-07-18" version="1">MSETNSLKNIATSFLKLLVVGAVDEAYANYVDNAFIHHNQHHKGDRESLKLGMQQAALKFTDMQLEVKSVLQEGDRVTTYSHIQSNLNNMDVAVFHMFKFKNDKIIELWDVGQQIIKDSPNENGFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXE5</accession>
    <name>A0A2S9GXE5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3040</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92381">
        <property type="protein sequence ID" value="PRC92381"/>
        <property type="gene ID" value="S2091_3040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015449926" evidence="1">
        <location>
            <begin position="19"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="159" mass="17828" checksum="3D493779F51ADE41" modified="2018-07-18" version="1">MRLIFFLLFILKMNLCIADSPSREPYEYKVCSSGNTFCAKVSPVSGISVYRIGSPKLEESVSITKDWYPQVYLSNDGQKVLTIGTTIVPRYEFDQPVVKIFVGAKLDRSLCVKDLIAKRDLVRTSSGFSWGYPVGFSDGDATFTFKLLTNGDFKISIDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXF4</accession>
    <name>A0A2S9GXF4_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptide methionine sulfoxide reductase MsrA</fullName>
            <shortName evidence="4">Protein-methionine-S-oxide reductase</shortName>
            <ecNumber evidence="4">1.8.4.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Peptide-methionine (S)-S-oxide reductase</fullName>
            <shortName evidence="4">Peptide Met(O) reductase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">msrA</name>
        <name evidence="6" type="ORF">S2091_2768</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 4">
            <text>[thioredoxin]-disulfide + H2O + L-methionine = [thioredoxin]-dithiol + L-methionine (S)-S-oxide</text>
            <dbReference type="Rhea" id="RHEA:19993"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:58772"/>
            <dbReference type="EC" id="1.8.4.11"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 4">
            <text>[thioredoxin]-disulfide + H2O + L-methionyl-[protein] = [thioredoxin]-dithiol + L-methionyl-(S)-S-oxide-[protein]</text>
            <dbReference type="Rhea" id="RHEA:14217"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="Rhea" id="RHEA-COMP:12313"/>
            <dbReference type="Rhea" id="RHEA-COMP:12315"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16044"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:44120"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="EC" id="1.8.4.11"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the MsrA Met sulfoxide reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.8.4.11" evidence="4"/>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92393">
        <property type="protein sequence ID" value="PRC92393"/>
        <property type="gene ID" value="S2091_2768"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033744">
        <property type="term" value="F:L-methionine:thioredoxin-disulfide S-oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008113">
        <property type="term" value="F:peptide-methionine (S)-S-oxide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1060.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01401">
        <property type="entry name" value="MsrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002569">
        <property type="entry name" value="Met_Sox_Rdtase_MsrA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036509">
        <property type="entry name" value="Met_Sox_Rdtase_MsrA_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01625">
        <property type="entry name" value="PMSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55068">
        <property type="entry name" value="SSF55068"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00401">
        <property type="entry name" value="msrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PMSR" evidence="5">
        <location>
            <begin position="6"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01625"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC92393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="173" mass="19306" checksum="AA1F3A190A0FE30E" modified="2018-07-18" version="1">MAIEIATIGGGCFWCTEAVYQELKGVTQIISGYAGGSVLNPTYEQVCTGTTGHAEVVQLSFDTDVVSYRKILEVFFTIHDPTTLNRQGNDVGTQYRSVVFYHADEQHEMAKHVIAEMASVWDAPLVTELSPVPTFYSAEAYHQNYYRQHPDQGYCAFVVATKVAKFRKMFISG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXM6</accession>
    <name>A0A2S9GXM6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Esterase, PHB depolymerase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2836</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92461">
        <property type="protein sequence ID" value="PRC92461"/>
        <property type="gene ID" value="S2091_2836"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010126">
        <property type="entry name" value="Esterase_phb"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10503">
        <property type="entry name" value="Esterase_PHB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01840">
        <property type="entry name" value="esterase_phb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="344" mass="38579" checksum="FCDDCEABC644CE91" modified="2018-07-18" version="1">MMKDSLSSKLPYNLKDAKQIIWRRTWNKPAARFLGTFLGLKQRFFNTVLRRKNELDDLGQSQFLNDSFTNFSGSLRYHLFIPSNHHAGMSLLVMLHGCNQDAEIFSVGTRMNEHAEQLGFMVLYPAQSGAANANKCWNWFKSANQYRNMGEPAVIAGMTKKIMREYAINSRKVYIAGLSSGAAMAYIVGSVYADIFAAIGVHSGLLYRGVNNIFSALAAMKAGSEQAGQTSEITEQELAPRITQPLIIFHGDNDQVVHAQNAIDLMAYHHQQEFFKQHSHHESEKNYSHTRTIYKDANGADLAEKWIIHGAGHAWSGGCVDGNFTDPKGPDASFEMLRFFMKLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXT7</accession>
    <name>A0A2S9GXT7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glyoxalase-like domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2896</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92521">
        <property type="protein sequence ID" value="PRC92521"/>
        <property type="gene ID" value="S2091_2896"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="57" mass="6462" checksum="3EA3EB6CC9BEA073" modified="2018-07-18" version="1">MINYAVDDMDAIPSRLLAKGVTVLKRTDDDPNGRLARILDPEDNKIELWEPKRKASP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXY8</accession>
    <name>A0A2S9GXY8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2637</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92582">
        <property type="protein sequence ID" value="PRC92582"/>
        <property type="gene ID" value="S2091_2637"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021102">
        <property type="entry name" value="PNGase_A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31104">
        <property type="entry name" value="PTHR31104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12222">
        <property type="entry name" value="PNGaseA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015505653" evidence="1">
        <location>
            <begin position="29"/>
            <end position="593"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="593" mass="63708" checksum="ADF6C8674F87E205" modified="2018-07-18" version="1">MRSCFASHPVIIFSSILLSSLLSTSATAAALPPGFTLGSANVAIADPAVPRPSSQPCTVVLFSNQQFADFNNHSFNYAPPAACPGPWSKVVLEVDLSINAGNQYDRTAHIWLGGVNIYTGTTEEPSATVARNWHVERDITDYSALLNAAQQGSVDLGNIVNSTYTGILQGTATLQLYPAVPGFKPARTPDVVYPMSASATGGAVALNTTTDQLTQTITFPRNVERAFIDVLAQGQSGDEFWYTCVPNALSSQLQSCGSTAFREAEISIDGQAAGVAPVYPWIFTGGIDPLLWRPTPGVQTLNLLPYRVDISPFAAQLSNGQSHTVAISVYNANNYFLASGAVLVYRDPKTVQVTGALTSNTLAAIVAPTINNQLVTDSQGNVTGTLTTSSKRNFKIAGYIQTSHGRIDTMVTQNMHYQNKQAFTINSSDYVQNISQQTEVETDTGVFSNGSEAHEHHHANFPLTMNINYATPPGQPVTQATTVVQAFDNSNWLALNGWMIYQSEVHNKVSPSDTLNFDASGNFTGNSGQQSVQKYTFTDSTGSCYKRTVTSSAGLLTAVTDGKDCRGNQNAPRWFVDPYGIALPDLSTLNMYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GY25</accession>
    <name>A0A2S9GY25_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2682</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92627">
        <property type="protein sequence ID" value="PRC92627"/>
        <property type="gene ID" value="S2091_2682"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021686">
        <property type="entry name" value="DUF3268"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11672">
        <property type="entry name" value="DUF3268"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="162" mass="18254" checksum="CE1EAD3EBE09787B" modified="2018-07-18" version="1">MYEAMKKSGVLPKRTAPITPSNPSRKATARVRNPLPIPTICPHCKSAVELVNNSEIYGREYGEWPWAYRCEGDDCDSYVGLHPFTNIPLGTLANEDVRDARKKAKNIFNPIWQSRGMTRSAAYAWLAEALGIQDVNECHIGWFDVETCERVFALCNDKLHAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GY45</accession>
    <name>A0A2S9GY45_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92645">
        <property type="protein sequence ID" value="PRC92645"/>
        <property type="gene ID" value="S2091_2700"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="60" mass="7221" checksum="4DD3DE2176FD6EB8" modified="2018-07-18" version="1">MTELKQAEELASRASTRFYEVDSKVIADKREKKNTEGLLEDWNVKRREWRHAECVLEKLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYE0</accession>
    <name>A0A2S9GYE0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2472</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92742">
        <property type="protein sequence ID" value="PRC92742"/>
        <property type="gene ID" value="S2091_2472"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="29" mass="3363" checksum="4431F105983BDA6F" modified="2018-07-18" version="1">MDTTMGSFEAYFIDAVRALEYEPYNNRSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYI8</accession>
    <name>A0A2S9GYI8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glutathione S-transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2514</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92784">
        <property type="protein sequence ID" value="PRC92784"/>
        <property type="gene ID" value="S2091_2514"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00043">
        <property type="entry name" value="GST_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13409">
        <property type="entry name" value="GST_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="SSF47616"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GST N-terminal" evidence="1">
        <location>
            <begin position="3"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="2">
        <location>
            <begin position="90"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="216" mass="24125" checksum="4F1A83A90855611D" modified="2018-07-18" version="1">MALILYTGTKNASSWALRAWLPLRELNIPFQEHVVDIRRPQRYANLAKIAEFSVPGAVPVLVDDGVVIFDSLAVMEYANELGGGTLLPKEIRLRAHARSLVAWVHSGMSELCSSISFESSFYKEHTPLSATETAEVESVFAIWEQELARSGGPFLVGELSLADLTFVPTIRRLLSRDVSIAEWPLAQAWTERMISRQSVVEWMREAESLPPVISDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYU6</accession>
    <name>A0A2S9GYU6_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">4-hydroxy-tetrahydrodipicolinate synthase</fullName>
            <ecNumber evidence="4">4.3.3.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">S2091_2300</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>L-aspartate 4-semialdehyde + pyruvate = (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + H(+) + H2O</text>
            <dbReference type="Rhea" id="RHEA:34171"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:67139"/>
            <dbReference type="ChEBI" id="CHEBI:537519"/>
            <dbReference type="EC" id="4.3.3.7"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; (S)-tetrahydrodipicolinate from L-aspartate: step 3/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the DapA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.3.3.7" evidence="4"/>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92883">
        <property type="protein sequence ID" value="PRC92883"/>
        <property type="gene ID" value="S2091_2300"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00034">
        <property type="reaction ID" value="UER00017"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008840">
        <property type="term" value="F:4-hydroxy-tetrahydrodipicolinate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019877">
        <property type="term" value="P:diaminopimelate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005263">
        <property type="entry name" value="DapA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002220">
        <property type="entry name" value="DapA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020625">
        <property type="entry name" value="Schiff_base-form_aldolases_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12128">
        <property type="entry name" value="PTHR12128"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00701">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001365">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00146">
        <property type="entry name" value="DHPICSNTHASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01130">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00674">
        <property type="entry name" value="dapA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00666">
        <property type="entry name" value="DHDPS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0220">Diaminopimelate biosynthesis</keyword>
    <keyword evidence="9" id="KW-0456">Lyase</keyword>
    <keyword evidence="7" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0704">Schiff base</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR001365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC92883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="295" mass="32052" checksum="B96BE2F0698689E5" modified="2018-07-18" version="1">MKINGVIVPIVTPFDKENRLDLAALEKLLEHFIEKGVHGVVACGTTGEYYALNDVERQQVLACIARVAKGRISLIAGANDLSTQGAILRAKQAAELGYEALMMAPPAYSLPNQAEIIAHYKAVAEVSPLPIIMYNFPARAGVEIDIDSVLELAKLPNIIGLKESSGNFSRALAIIQAKLPNFEVVCGCDDQAADFLFWGVTSWISGAANVFPAEQVAMLRAAQGKDWAEVKQLMTAMYPVIQSMESGGYNQKAKLGCLRHDIQVGEVRQPLQSISATEATHFQQLMQQFIATQAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYV2</accession>
    <name>A0A2S9GYV2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Pyruvate/2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2305</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92888">
        <property type="protein sequence ID" value="PRC92888"/>
        <property type="gene ID" value="S2091_2305"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005475">
        <property type="entry name" value="Transketolase-like_Pyr-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033248">
        <property type="entry name" value="Transketolase_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02779">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02780">
        <property type="entry name" value="Transketolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00861">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="SSF52922"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transket_pyr" evidence="1">
        <location>
            <begin position="22"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="355" mass="38950" checksum="7F14A54F89C2D5C4" modified="2018-07-18" version="1">MEEVMDKAMDQKTSQKTKPMTMTMIQALRSAMDVMLERDNNVVVFGQDVGYFGGVFRCTEGLQQKYGTSRVFDTPISEGGIVGVAIGMGAYGLRPVVEIQFADYFYPACDQIVSEAARLRYRSAGQFIAPLTIRMPCGGGIYGGQTHSQSPEAMFTHVCGLRTVMPSNPYDAKGLLISCIENDDPVIFLEPKRLYNGPFDGHHDKPVVPWSKHPLGEVPEGYYTVPLDSASIFRAGSDLTVLAYGTMVFVSEAAAKESGVDAEIIDLRSIWPLDLATIVASVKKTGRCVIVHEATHTSGFGAELSALVQEHCFYHLEAPIERVTGWDTPYPHAQEWAYFPGPGRIAAAFKRTMEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYX1</accession>
    <name>A0A2S9GYX1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2317</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92900">
        <property type="protein sequence ID" value="PRC92900"/>
        <property type="gene ID" value="S2091_2317"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="368" mass="40185" checksum="BFC35D41EA9CFEFA" modified="2018-07-18" version="1">MSGPTTAIIVADPVALLLSAAGIRAAMAIRQGYEDSAALAAEHAAQHGQILQTQHAANLQGQQAMLQQLAQSEAEFAQLSQLADSLGASERILAGRPTRPDTTNDNDAALISYLRTLQSYSAELKSILLTESARLMGSTGSDETPAFQEFANLAASEVEPESDAVMQTAARLLARIAHLGALPQQIQQLAQQLNRNLPTERAELLTSELRRQIQLHLEQTQQQQVQEATALVLQQSLKDLGYQVEEFSSTLFVEGGVVHFRRHDWGAYMVRMRINEATGTANFNVIRSVTNASNERSVLDHLAEDRWCAEFPALLKALEACGLGLNVTRRLEAGELPVQLVNKDLLPQFAEHEDARTSAPLLSREIPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZ07</accession>
    <name>A0A2S9GZ07_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phasin: phasin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2360</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92943">
        <property type="protein sequence ID" value="PRC92943"/>
        <property type="gene ID" value="S2091_2360"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018968">
        <property type="entry name" value="Phasin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010127">
        <property type="entry name" value="Phasin_subfam-1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09361">
        <property type="entry name" value="Phasin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01841">
        <property type="entry name" value="phasin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phasin_2" evidence="2">
        <location>
            <begin position="8"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="167"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="186" mass="20333" checksum="2F7ACB3C101EA5B0" modified="2018-07-18" version="1">MSASTQEKMIGTIQEQQAQWLAFVAKALESSMKLVELNARMTKQSLDDSSQSLRYLLEVKAPGQIFALDAERIQDKLNRMLSYANEFSAITSAFGTEFSQIAQAQISGSCNNANKLFEGAQQVTPDTLQKPFDVMFSALGNPQNGYEQWMGAGKKFAEVIGQNLMMTPSESAPAKRKSAKSTSNGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZF8</accession>
    <name>A0A2S9GZF8_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein-arginine rhamnosyltransferase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">EF-P arginine rhamnosyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_2200</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Protein-arginine rhamnosyltransferase that catalyzes the transfer of a single rhamnose to elongation factor P (EF-P) on 'Lys-32', a modification required for EF-P-dependent rescue of polyproline stalled ribosomes.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>dTDP-beta-L-rhamnose + L-arginyl-[protein] = dTDP + H(+) + N(omega)-(alpha-L-rhamnosyl)-L-arginyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:66692"/>
            <dbReference type="Rhea" id="RHEA-COMP:10532"/>
            <dbReference type="Rhea" id="RHEA-COMP:17096"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29965"/>
            <dbReference type="ChEBI" id="CHEBI:57510"/>
            <dbReference type="ChEBI" id="CHEBI:58369"/>
            <dbReference type="ChEBI" id="CHEBI:167445"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="3">
            <dbReference type="Rhea" id="RHEA:66693"/>
        </physiologicalReaction>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the glycosyltransferase 104 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93114">
        <property type="protein sequence ID" value="PRC93114"/>
        <property type="gene ID" value="S2091_2200"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106361">
        <property type="term" value="F:protein-arginine rhamnosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016633">
        <property type="entry name" value="EarP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10093">
        <property type="entry name" value="EarP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015557">
        <property type="entry name" value="UCP015557"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03837">
        <property type="entry name" value="efp_adjacent_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00024303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00024346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00030025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC93114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="387" mass="43104" checksum="C32EB7DD5216FD7C" modified="2018-07-18" version="1">MHQKNHQARSLALFCKVIDNYGDIGICWRLALQLEREHGIAVTLWVDDLVSFQRICPEVVINCDVQHIGTIIVRHWLNQDGVFAADDVTDIVIEFFGCDIPPVYILAMAQRAVKPAWINLEGLTAEQWVEGCHRLPSSHPSLPLKKYFFYPGFTELTGGLLIESNLTLQRQKFQQDPAAMTAFLGQFGVTAAEMTSLKVSLFCYPQAPVAALFNAWECGATAVTCLVPEGVAADAVQLFLGQSAKAGATATRGALTVRVMPFVPQSDYDKLLWACDLNFVRGEDSFVRAQWAGQPFIWHIYPQDNDLHHVKLNAFLQRYKAKTQSLVDMSLNWNAVKGVVSPHELASTWLLLQADLPKIAALTSDWQQNMLANGNFTANLLKFIDGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZI7</accession>
    <name>A0A2S9GZI7_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Carbamoyl-phosphate synthase large chain</fullName>
            <ecNumber evidence="13">6.3.5.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Carbamoyl-phosphate synthetase ammonia chain</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">carB</name>
        <name evidence="17" type="ORF">S2091_2227</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>2 ATP + H2O + hydrogencarbonate + L-glutamine = 2 ADP + carbamoyl phosphate + 2 H(+) + L-glutamate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:18633"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58228"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.5.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="13">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="13">Binds 4 Mg(2+) or Mn(2+) ions per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="13">Amino-acid biosynthesis; L-arginine biosynthesis; carbamoyl phosphate from bicarbonate: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 13">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 1/3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="13">Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 13">Belongs to the CarB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.5" evidence="13"/>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93141">
        <property type="protein sequence ID" value="PRC93141"/>
        <property type="gene ID" value="S2091_2227"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00068">
        <property type="reaction ID" value="UER00171"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00070">
        <property type="reaction ID" value="UER00115"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004088">
        <property type="term" value="F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044205">
        <property type="term" value="P:'de novo' UMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006526">
        <property type="term" value="P:arginine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01424">
        <property type="entry name" value="MGS_CPS_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1030.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01210_A">
        <property type="entry name" value="CPSase_L_chain_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01210_B">
        <property type="entry name" value="CPSase_L_chain_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006275">
        <property type="entry name" value="CarbamoylP_synth_lsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005480">
        <property type="entry name" value="CarbamoylP_synth_lsu_oligo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036897">
        <property type="entry name" value="CarbamoylP_synth_lsu_oligo_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005479">
        <property type="entry name" value="CbamoylP_synth_lsu-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005483">
        <property type="entry name" value="CbamoylP_synth_lsu_CPSase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011607">
        <property type="entry name" value="MGS-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036914">
        <property type="entry name" value="MGS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033937">
        <property type="entry name" value="MGS_CPS_CarB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02786">
        <property type="entry name" value="CPSase_L_D2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02787">
        <property type="entry name" value="CPSase_L_D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02142">
        <property type="entry name" value="MGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00098">
        <property type="entry name" value="CPSASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01096">
        <property type="entry name" value="CPSase_L_D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00851">
        <property type="entry name" value="MGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48108">
        <property type="entry name" value="SSF48108"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52335">
        <property type="entry name" value="SSF52335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="SSF52440"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01369">
        <property type="entry name" value="CPSaseII_lrg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00866">
        <property type="entry name" value="CPSASE_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00867">
        <property type="entry name" value="CPSASE_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51855">
        <property type="entry name" value="MGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="13" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="9 13 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 13" id="KW-0436">Ligase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="12" id="KW-0464">Manganese</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 13 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11 13" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 13" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="ATP-grasp" evidence="15">
        <location>
            <begin position="133"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-grasp" evidence="15">
        <location>
            <begin position="673"/>
            <end position="868"/>
        </location>
    </feature>
    <feature type="domain" description="MGS-like" evidence="16">
        <location>
            <begin position="935"/>
            <end position="1072"/>
        </location>
    </feature>
    <feature type="region of interest" description="Carboxyphosphate synthetic domain" evidence="13">
        <location>
            <begin position="1"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="region of interest" description="Allosteric domain" evidence="13">
        <location>
            <begin position="935"/>
            <end position="1072"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="285"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="299"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="301"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="823"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="839"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="841"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>4</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="PRC93141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="1072" mass="117680" checksum="C80A28D0C53304BF" modified="2018-07-18" version="1">MPKRSDIKSILIIGAGPIIIGQACEFDYSGAQACKALREEGYKVILVNSNPATIMTDPEMADVTYIEPITWQVVERIIAKERPDAILPTMGGQTALNCALDLHRHGVLEKYSCELIGASPEAIDKAEDRSKFKAAMTKIGLGSARSDVAHTLEESWAVQRTLGFPVIIRPSFTMGGTGGGIAYNEEEFETICKRGLEASPTSELLIEESLIGWKEFEMEVVRDSADNCIIVCSIENLDPMGVHTGDSITVAPAQTLTDKEYQIMRNASIAVLREIGVDTGGSNVQYAINPADGRMIVIEMNPRVSRSSALASKATGFPIAKIAAKLAVGYTLNELRNDITGSATPASFEPTIDYVVTKIPRFTFEKFPQANDHLTTQMKSVGEVMAIGRTFQESFQKALRGLEVGVDGLNEKTRDHEVIKEELGEPGPERIWYVGDAFAQGFSLEEVHQLTHIDPWFLAQIKDIVDIELWLETQKLEQLDKNILFRLKQKGFADRRLAKLLHTTDKEVREYRHSLNIFPVYKRVDTCAAEFATKTAYMYSTYEEECESLPTNNKKIMVLGGGPNRIGQGIEFDYCCVHAALAMREDGYETIMVNCNPETVSTDYDTSDRLYFEPVTLEDVLEIVAKEKPIGVIVQYGGQTPLKLALDLEANGVPIIGTSPDMIDAAEDRERFQKLLHELNLRQPPNRTARTEEDALRLAAEIGYPLVVRPSYVLGGRAMEIVHEQRDLERYMREAVKVSHDSPVLLDRFLNDAIEVDVDCLSDGERTFIGGVMEHIEQAGVHSGDSACSLPPYSLSAETIAELKRQTSLMAKGLNVVGLMNVQFAIQQAEGKDVVFVLEVNPRASRTVPFVSKVTGLQLAKIAARCMAGQSLDSQGIINEVVPSYYSVKEAVFPFVKFPGVDTILGPEMKSTGEVMGVGKTFGEAFVKSQLGAGVHLPKAGKVFLSVKNNDKPRAVKVAANLVKMGFTILATKGTAAQISAAGVPVTPVNKKSEGRPHIVDMIINREIALVINTVEEKRSAIQDSGAIRVSSLAARVTTFTTIAGAEAAVEGMRHLDELHVYDLQGLHKTLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZS5</accession>
    <name>A0A2S9GZS5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1977</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93239">
        <property type="protein sequence ID" value="PRC93239"/>
        <property type="gene ID" value="S2091_1977"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="88" mass="9383" checksum="9378591A4DB66230" modified="2018-07-18" version="1">MKKTGMAKSSAKKLMGKMVAPGASEFGKGDVAVIDRREQRKLDQALGLVPFAVKLNSTLVQQLEVQAKERGIELNAFVAEVLAKGLAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H023</accession>
    <name>A0A2S9H023_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_2036</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93298">
        <property type="protein sequence ID" value="PRC93298"/>
        <property type="gene ID" value="S2091_2036"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025645">
        <property type="entry name" value="DUF4349"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14257">
        <property type="entry name" value="DUF4349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015773010" evidence="3">
        <location>
            <begin position="23"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="227"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="164"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC93298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="270" mass="29516" checksum="E12C69BC8DE6EA68" modified="2018-07-18" version="1">MKRLLFCSFLIASLSACSHKEAGMSPDSAPAAKMAASGASLQKQYLAYQHTIRIDTDEQKVTLIFNAGQAACLAAVSEHCVILASELSTGRSSSAYLKIRATAAGIQKLITALSTQGPITSQATTAEDLAGSIEDAVKKLAMLTSYRHQLEELQAKPGSNIDTLIKLNKELAEVQSEIEAMTGKQAQLMQRVETETLSVYIDSAHRSGFWTPIKQALSEFTGNLSQAMSALITFIAFMLPWSVLLALLLWIVRKIWRRWKAPKTLKVKNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0L8</accession>
    <name>A0A2S9H0L8_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">L-arabinose-binding periplasmic protein</fullName>
            <shortName evidence="1">ABP</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_1793</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial solute-binding protein 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93406">
        <property type="protein sequence ID" value="PRC93406"/>
        <property type="gene ID" value="S2091_1793"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042882">
        <property type="term" value="P:L-arabinose transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01540">
        <property type="entry name" value="PBP1_arabinose_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026266">
        <property type="entry name" value="AraF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001761">
        <property type="entry name" value="Peripla_BP/Lac1_sug-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00532">
        <property type="entry name" value="Peripla_BP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002816">
        <property type="entry name" value="AraF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0574">Periplasm</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015377488" description="L-arabinose-binding periplasmic protein" evidence="1">
        <location>
            <begin position="27"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="domain" description="Peripla_BP_1" evidence="3">
        <location>
            <begin position="37"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="site" description="The binding site for the sugar molecule has not yet been established, but C-87 may be involved" evidence="2">
        <location>
            <position position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR002816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR002816-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC93406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="336" mass="35928" checksum="5358DC3EC864A031" modified="2018-07-18" version="1">MNTQLTSLLRSLPLLAAFISSNLVEAAEPQKPGEPIKIGFLVKQAEEPWFQDEWRFAEQAAREKGFTLIKIGTPNGEKMMAAIDNLAAQKAQGFVICAPDVKLGVAIERAAMRNSLKVMAVDDQLIDASGKPVTSIPYMGISGGDIGRQVGQGLISAMKERGWQPSEVGALRMAFDQLPTARERTMGAAEVLKAAGVPSANIIDASQGKSDTESAFNAANIAFTKQAHFKHWLVFGMNDEAVLGAVRAAESHGLKSDSLIGIGIGGSKTAQNEFAKPMITGFYGTVLISPKRHGYETALNMYKWIVDNQQPVAVTLTAGTLMTRVNQAAVRAANGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0M3</accession>
    <name>A0A2S9H0M3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Efflux transporter, RND family, MFP subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1904</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93517">
        <property type="protein sequence ID" value="PRC93517"/>
        <property type="gene ID" value="S2091_1904"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006143">
        <property type="entry name" value="RND_pump_MFP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01730">
        <property type="entry name" value="RND_mfp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HlyD_D23" evidence="2">
        <location>
            <begin position="67"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="383" mass="40744" checksum="D48511AE62A68D88" modified="2018-07-18" version="1">MNNFILSLRYGRLGRFALFAITLLVSGCSKPIDNVNEVRPVRVIKLTSTNAEIDAEFAGEVRARIESRLGFRVGGKIVSRAVEVGSLVKSGQILMQLDPLDQKLAQAQAVAALTASESNRDLASAELKRYLNLRDKNFVSQAVLDSKEGAFKSAEAAYEQSVAINKSQSNQVNYTTLVANADGVVTNINAEVGQVVVAGADILRVAELAEKEVVIGIPENKVDTLRTTSDVQVRIWAHPKDLIAGKIREISPIADPATRTFITKVSLIDAPADVHLGMTAYVIFSAKSANQSIKVPLTALFQDKGSSAVWVVENNLTKLTRVEIGAPIGNDIILTGGVSNGQMVVTAGVNSLKQGQRVRVLDEEPVTNASSAAAAAGTGAVVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0Y0</accession>
    <name>A0A2S9H0Y0_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 10">Sec translocon accessory complex subunit YajC</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">yajC</name>
        <name evidence="11" type="ORF">S2091_1643</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Part of the SecDF-YidC-YajC translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the YajC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93642">
        <property type="protein sequence ID" value="PRC93642"/>
        <property type="gene ID" value="S2091_1643"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003849">
        <property type="entry name" value="Preprotein_translocase_YajC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33909">
        <property type="entry name" value="PTHR33909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02699">
        <property type="entry name" value="YajC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01853">
        <property type="entry name" value="YAJCTRNLCASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01323">
        <property type="entry name" value="YajC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00739">
        <property type="entry name" value="yajC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0811">Translocation</keyword>
    <keyword evidence="7 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5 10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004377"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU366028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC93642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="109" mass="11945" checksum="FE5DFBC0C2950DF5" modified="2018-07-18" version="1">MFISNAYAQSAATPGLMDGNLMSFLPIIMMFVVLYFLMIRPQMKRQKEQKAMMDALAKNDEVITVGGILGKVTKVADGYVTVEIADNTEVVIQKSAVTMLLPKGTIKTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0Y4</accession>
    <name>A0A2S9H0Y4_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 4">Phosphatase NudJ</fullName>
            <ecNumber evidence="4">3.6.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">nudJ</name>
        <name evidence="6" type="ORF">S2091_1614</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="2 4">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the Nudix hydrolase family. NudJ subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.-" evidence="4"/>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93613">
        <property type="protein sequence ID" value="PRC93613"/>
        <property type="gene ID" value="S2091_1614"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017110">
        <property type="term" value="F:nucleoside-diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017111">
        <property type="term" value="F:nucleoside-triphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004787">
        <property type="term" value="F:thiamine-diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03675">
        <property type="entry name" value="Nudix_Hydrolase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033713">
        <property type="entry name" value="NudJ"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="5">
        <location>
            <begin position="4"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007608"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU364043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC93613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="159" mass="18197" checksum="005E479A40C06503" modified="2018-07-18" version="1">MSDIWKPAVTVAAIIERNGLFFMIEEETSDGLRINQPAGHLDPEESLIDAVIRETKEETAHEFMPSYLVGTYLSRYMSKRRGIPVSYLRFAFAGKLGQEYQQPLDVGIVRTMWMSYDELVATKERHRSELILRCIDDYLAGARIPLSFIYTDSSVTEPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H101</accession>
    <name>A0A2S9H101_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative redox protein regulator of disulfide bond formation</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1665</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93664">
        <property type="protein sequence ID" value="PRC93664"/>
        <property type="gene ID" value="S2091_1665"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003718">
        <property type="entry name" value="OsmC/Ohr_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036102">
        <property type="entry name" value="OsmC/Ohrsf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02566">
        <property type="entry name" value="OsmC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82784">
        <property type="entry name" value="SSF82784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="145" mass="15564" checksum="B63903D97617FBA3" modified="2018-07-18" version="1">MECTVRWTGQSGMTFLAETGSGHVVAMDGAPDGGGRNLAPRPMEMVLLGTGGCTAYDVVLILRKGGQTITNCDVKLTAERAEKEPKVFTKVHFHFTVSGSNIKVSAVERAIKLSHEKYCSASIMLEKTAEITHSYEIVDDSIASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1C2</accession>
    <name>A0A2S9H1C2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="8">P pilus assembly protein chaperone PapD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_1391</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the periplasmic pilus chaperone family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93782">
        <property type="protein sequence ID" value="PRC93782"/>
        <property type="gene ID" value="S2091_1391"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030288">
        <property type="term" value="C:outer membrane-bounded periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061077">
        <property type="term" value="P:chaperone-mediated protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008962">
        <property type="entry name" value="PapD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036316">
        <property type="entry name" value="Pili_assmbl_chap_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001829">
        <property type="entry name" value="Pili_assmbl_chaperone_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016148">
        <property type="entry name" value="Pili_assmbl_chaperone_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016147">
        <property type="entry name" value="Pili_assmbl_chaperone_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02753">
        <property type="entry name" value="PapD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00345">
        <property type="entry name" value="PapD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00969">
        <property type="entry name" value="CHAPERONPILI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49354">
        <property type="entry name" value="SSF49354"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49584">
        <property type="entry name" value="SSF49584"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0574">Periplasm</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015543957" evidence="5">
        <location>
            <begin position="25"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="domain" description="PapD_N" evidence="6">
        <location>
            <begin position="26"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="domain" description="PapD_C" evidence="7">
        <location>
            <begin position="174"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC93782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="252" mass="28169" checksum="E08D7EC3EE725AC7" modified="2018-07-18" version="1">MRKNWKIIGSALFLSVLTMAPALASVVMTNTRVIYPANAREKSIQLTNQDSLPSVMQVWIDSGDDKSTPETAEAPFLVTPPLFRIEPNEGQTIRLVFIGEGLPQDRESVFYLNTVQIPSLDANSADQNQMIVMLRNRIKLFYRPTTIKGGIERATDQFSFSVQQEGADWRVTAENKSGYHISLVNAKVVSNAQEFPFEPSMVAPYSKADWVIKNPGHPMQLPMTVNYSFINDYGGTGQGEYKFNPDTPVTDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1F9</accession>
    <name>A0A2S9H1F9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1430</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93821">
        <property type="protein sequence ID" value="PRC93821"/>
        <property type="gene ID" value="S2091_1430"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015655582" evidence="1">
        <location>
            <begin position="28"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="245" mass="27915" checksum="3A296310EDDFCA65" modified="2018-07-18" version="1">MNIKQFPLVARYLVAFILCCFSLTALAQATDLGEFKDGAWVSYRDAYLKMIRFEKYGGPKQFIQNNLRVVVTDKKTSMDGLRLILEGKNTHLNLLLDPIGRAIFPMLKTAYDDNAELRVNRPDNSVTFEYRISIFTRPDGVYDVSDLRSACDQVLHYLRYQDLLRYTLKQCIGVKFSYLKDQYNISLKAKINDQNPVSISLSDGSVFNEDNFNMFKVGVYKFIGGTEKGQIISSNVPLAITAIIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H223</accession>
    <name>A0A2S9H223_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Histidinol dehydrogenase</fullName>
            <shortName evidence="4">HDH</shortName>
            <ecNumber evidence="4">1.1.1.23</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">hisD</name>
        <name evidence="11" type="ORF">S2091_1180</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>H2O + L-histidinol + 2 NAD(+) = 3 H(+) + L-histidine + 2 NADH</text>
            <dbReference type="Rhea" id="RHEA:20641"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57595"/>
            <dbReference type="ChEBI" id="CHEBI:57699"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.23"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4 9">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="4 9">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 9/9.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 5 10">Belongs to the histidinol dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.23" evidence="4"/>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94007">
        <property type="protein sequence ID" value="PRC94007"/>
        <property type="gene ID" value="S2091_1180"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00014"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004399">
        <property type="term" value="F:histidinol dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06572">
        <property type="entry name" value="Histidinol_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01024">
        <property type="entry name" value="HisD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001692">
        <property type="entry name" value="Histidinol_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022695">
        <property type="entry name" value="Histidinol_DH_monofunct"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012131">
        <property type="entry name" value="Hstdl_DH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21256">
        <property type="entry name" value="PTHR21256"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00815">
        <property type="entry name" value="Histidinol_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000099">
        <property type="entry name" value="Histidinol_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00083">
        <property type="entry name" value="HOLDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00069">
        <property type="entry name" value="hisD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00611">
        <property type="entry name" value="HISOL_DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="1 4 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 7" id="KW-0520">NAD</keyword>
    <keyword evidence="3 4 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4 9" id="KW-0862">Zinc</keyword>
    <feature type="active site" description="Proton acceptor" evidence="4 6">
        <location>
            <position position="337"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4 6">
        <location>
            <position position="338"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4 7">
        <location>
            <position position="140"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4 7">
        <location>
            <position position="201"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4 7">
        <location>
            <position position="224"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4 8">
        <location>
            <position position="247"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4 8 9">
        <location>
            <position position="269"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4 8 9">
        <location>
            <position position="272"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4 8">
        <location>
            <position position="338"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4 8 9">
        <location>
            <position position="371"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4 8">
        <location>
            <position position="425"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4 8 9">
        <location>
            <position position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR000099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000099-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000099-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000099-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000099-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC94007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="439" mass="46636" checksum="46D772F1CF52F7D7" modified="2018-07-18" version="1">MSAPIAITKLDSSTADFQQRLASLLAFETSQDDAIEHAVAQILTDVRQHGDAAVLAATQRFDRLTASSVAELEISKDEMQQALNSLPTERRIALETAAQRVRAYHQIQKQECGSSGFSYTEPDGTVLGQKVTPLDRVGIYVPGGKAAYPSSVLMNAIPAKVAGVAEVIMVVPTPDGVKNPLVLAAAFIAGVDKIFTIGGAQAVAALAYGTATIPAVDKIVGPGNAYVASAKRRVFGTVGIDMIAGPSEILVLCDGTTNPDWVAMDLFSQAEHDELAQSILLCPDADYIAAVERSINHLIATMPRQEIIRTSLTNRGALILVRDMDEACSIANSIAAEHVEISTQQPEHWAAKIRHAGALFLGRFSSEALGDYCAGPNHVLPTSRTARFSSPLGVYDFQKRSSMICVSEAGAQTLGKVAAELAYGEGLQAHARSAELRIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H294</accession>
    <name>A0A2S9H294_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_1275</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94102">
        <property type="protein sequence ID" value="PRC94102"/>
        <property type="gene ID" value="S2091_1275"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015562">
        <property type="term" value="F:efflux transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003423">
        <property type="entry name" value="OMP_efflux"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010131">
        <property type="entry name" value="RND_efflux_OM_lipoprot_NodT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02321">
        <property type="entry name" value="OEP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01845">
        <property type="entry name" value="outer_NodT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0564">Palmitate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1134">Transmembrane beta strand</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="48"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU362097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC94102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="487" mass="51948" checksum="5222E07F84CFDE48" modified="2018-07-18" version="1">MLMLMVPMKFHCCWKKVKFALLLGAVILAGCSVGPEYKRPDIAAPSAWHENASSSSPPISNTTAPETAHWPSTEWWHGFACAELDAYIAQAKLTNNDLAAAVARVRQADQLANIAGAALLPTLGASFTALNEREQATTGNYVAVKQFSPQLNASYMLDFWGKNRAAQDAAIATAAASRHDQVTVELTVISSVAQSYFQSLALRERVAVAEHNLANAEITLKGLQQQLHAGVATALDVAQQETTVATLAAALPPLRLQLRQTLNALAILVGKTPETVEVSNQTLADLTVPEVRPGLPSELLERRPDVAEAEDQLIAANANIGVARAAFFPSIELTASYGYASSALAGMTNSANIIHTLAAGITQPIFDGGAIKGQYEFSKARYDELLANYRKAILSALGNVEDALVAVQQNTEQVKRLEFAVQKAARAHHIAQAQLHAGTVNILAVLNTETALFTAQDALIQAKNSHLEAYLSLFGALGGGWQKEAGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H295</accession>
    <name>A0A2S9H295_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 8">S-(hydroxymethyl)glutathione dehydrogenase</fullName>
            <ecNumber evidence="5 8">1.1.1.284</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">S2091_1284</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>NAD(+) + S-(hydroxymethyl)glutathione = H(+) + NADH + S-formylglutathione</text>
            <dbReference type="Rhea" id="RHEA:19985"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57688"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58758"/>
            <dbReference type="EC" id="1.1.1.284"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>NADP(+) + S-(hydroxymethyl)glutathione = H(+) + NADPH + S-formylglutathione</text>
            <dbReference type="Rhea" id="RHEA:19981"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57688"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:58758"/>
            <dbReference type="EC" id="1.1.1.284"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3 8">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4 8">Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.284" evidence="5 8"/>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94111">
        <property type="protein sequence ID" value="PRC94111"/>
        <property type="gene ID" value="S2091_1284"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106322">
        <property type="term" value="F:S-(hydroxymethyl)glutathione dehydrogenase NAD activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106321">
        <property type="term" value="F:S-(hydroxymethyl)glutathione dehydrogenase NADP activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006069">
        <property type="term" value="P:ethanol oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08300">
        <property type="entry name" value="alcohol_DH_class_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014183">
        <property type="entry name" value="ADH_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02818">
        <property type="entry name" value="adh_III_F_hyde"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0520">NAD</keyword>
    <keyword evidence="7 8 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="PKS_ER" evidence="9">
        <location>
            <begin position="13"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012309"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00021865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC94111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="374" mass="39867" checksum="C3642EAFB3CA3FF9" modified="2018-07-18" version="1">MNFIKTRAAVAWAANQPLSIEEVDLMPPQAGEVLVKIIASGVCHTDAYTLSGKDSEGIFPVILGHEGAGIVMALGSGVTSVAIGDHVIPLYTPECGECKFCKSGKTNLCQKIRETQGRGVMPDGTTRFYKDGKPIYHYMGTSTFSEYTVLPEISLAKINKEAPLEEVCLLGCGVTTGMGAVMNTAKVKAGDTVAIFGLGGIGLSAIIGARMAGASRIIGIDINTSKFALAKQLGATDLINPAELDQPIHQAIIAMTDGGVDFSFECIGNVNVMRQALECCHKGWGESIIIGVAEAGAEITTRPFQLVTGRVWRGSAFGGVRGRSELPSYVDRYMKGEFALSDFITHTMPLEEINTAFDLMHEGKSIRSVIHFAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2A1</accession>
    <name>A0A2S9H2A1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposase IS66 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1159</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC93986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93986">
        <property type="protein sequence ID" value="PRC93986"/>
        <property type="gene ID" value="S2091_1159"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004291">
        <property type="entry name" value="Transposase_IS66_central"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03050">
        <property type="entry name" value="DDE_Tnp_IS66"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_Tnp_IS66" evidence="1">
        <location>
            <begin position="2"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="166" mass="18977" checksum="1E8CE9390B408D2C" modified="2018-07-18" version="1">MAERLSELLKQRSVLHADETPVPQLDPRKGKTKRAYLRAYRSNNLEAGAPIVVFEFQASRSGTHVQDFLADWRGHLMVDDYGGYKHLFKQGITELACLAHARRKFFDLHAANQHPIAEEALQRIAELYRLESEAAGYSIEERQRWRAEHAKPARKAVSCRAPLITV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2D6</accession>
    <name>A0A2S9H2D6_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">30S ribosomal protein S8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpsH</name>
        <name evidence="7" type="ORF">S2091_1301</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the universal ribosomal protein uS8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94128">
        <property type="protein sequence ID" value="PRC94128"/>
        <property type="gene ID" value="S2091_1301"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01302_B">
        <property type="entry name" value="Ribosomal_S8_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000630">
        <property type="entry name" value="Ribosomal_S8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035987">
        <property type="entry name" value="Ribosomal_S8_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11758">
        <property type="entry name" value="PTHR11758"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00410">
        <property type="entry name" value="Ribosomal_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56047">
        <property type="entry name" value="SSF56047"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00053">
        <property type="entry name" value="RIBOSOMAL_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC94128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="131" mass="14062" checksum="48ADB18DA6D9BA16" modified="2018-07-18" version="1">MSMSDPIADMLTRIRNAQVVHKTAVAMPSSKVKVAIANVLKDEGYIEDFAISETAGKAELKIGLKYYAGRPVIERLERVSRPGLRIYKGKGDIPNVMNGLGVAIVSTPQGVMTDRKARATGVGGEVICYVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2G5</accession>
    <name>A0A2S9H2G5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Two-component sensor kinase N-terminal</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_1323</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94150">
        <property type="protein sequence ID" value="PRC94150"/>
        <property type="gene ID" value="S2091_1323"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013727">
        <property type="entry name" value="2CSK_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08521">
        <property type="entry name" value="2CSK_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="172"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="domain" description="2CSK_N" evidence="6">
        <location>
            <begin position="21"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08521"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC94150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="295" mass="33039" checksum="C456D8EE2264A46E" modified="2018-07-18" version="1">MFKPLRSLKSRLILWVFLPALLISFVDLLFTYNSTDKIATLVQEQLLKSSAKIMSEQINLINGEVEFNLPPAAFELFASPYQDHVYYSIRSEQGKLIAGADEIAPLNIDIPLEQAHYFSSRVGSESVRFIAYAHALPTGSAHDIVITQIAQTQKGQAAFRQELFMLTMRRHFMLLCMVLAGLMVASRWALRPLISFGEKITQRQGGSLEQLDTKDVPSELLPVISAMNDYVMRLDNTLSSYEQFVASTAHQLRTSFAVLTSQLNFGRRSATLDSTQNEVFIALQKTVAQGSKVIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2H8</accession>
    <name>A0A2S9H2H8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">MarR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1341</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94168">
        <property type="protein sequence ID" value="PRC94168"/>
        <property type="gene ID" value="S2091_1341"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01047">
        <property type="entry name" value="MarR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="1">
        <location>
            <begin position="25"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="223" mass="24317" checksum="9606CE788EC10AE3" modified="2018-07-18" version="1">MAKIDFDEAKSWVTSALSLHAHDLIKALASRYQVSSSTASATVKKLEQAGVIKRTGAVNRPIFEAASNITVMQSYSLPLGDAEQIWQRDFAPFLMQDLNENLRKLISSSFTAIANNASQHSQGNSMHVIAEQTADHIELTVQDNGIGVFKQISKTKQCADLAAAAALLERSNSAIKALAQKFDFFLIEANGMHYPEQAAPAVDTETEELFEQGTTVIMELTLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2J4</accession>
    <name>A0A2S9H2J4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1353</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94180">
        <property type="protein sequence ID" value="PRC94180"/>
        <property type="gene ID" value="S2091_1353"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021279">
        <property type="entry name" value="DUF2721"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11026">
        <property type="entry name" value="DUF2721"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="75"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="106"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="152" mass="16940" checksum="09EF2DC98218A2D0" modified="2018-07-18" version="1">MNIQLDDIGKIIQLSIAPVFMLSGVGTHLIVLTNRLARIIDRSRKLEETLTPEALHHDIELDELYARSHLINRSITLSCLCALLICLVIATLFVSDALEIALAKPIASMFVLGILSLIGSFVYFLREIFVATRTLERDRLRRGGGIIRSDQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2W6</accession>
    <name>A0A2S9H2W6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Anthranilate/para-aminobenzoate synthases component I</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0904</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94283">
        <property type="protein sequence ID" value="PRC94283"/>
        <property type="gene ID" value="S2091_0904"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044249">
        <property type="term" value="P:cellular biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901576">
        <property type="term" value="P:organic substance biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005801">
        <property type="entry name" value="ADC_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019999">
        <property type="entry name" value="Anth_synth_I-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006805">
        <property type="entry name" value="Anth_synth_I_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015890">
        <property type="entry name" value="Chorismate_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11236">
        <property type="entry name" value="PTHR11236"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04715">
        <property type="entry name" value="Anth_synt_I_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00425">
        <property type="entry name" value="Chorismate_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00095">
        <property type="entry name" value="ANTSNTHASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56322">
        <property type="entry name" value="SSF56322"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Anth_synt_I_N" evidence="2">
        <location>
            <begin position="30"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="domain" description="Chorismate_bind" evidence="1">
        <location>
            <begin position="239"/>
            <end position="491"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="518" mass="57381" checksum="A34E002107F626F4" modified="2018-07-18" version="1">MLNQEQFLEYGKQGFNLVPLWQILPLPPQLEALSLYRVLCMQGNDYLFETGQWEGGNFQRHYSIIGLPAAERIEIGEHWFKHIKEGEIIQELSTSEPLDELERLLASFRVPQIAALPPFSGGLFGYFGFETTRLIEPRLARQPRKPSGLDVPDVVQLVSKELLVFDHRQSQLFCIVHDDPGVADSYLRTHNRLYALCEHVLHKMTEIATNFPAQTYAPKTTTHAAPALHDELTYAFPRAQFEQAVGAIKTYIAAGDVMQVVLSQRMSRSLSCDAPTLYQALRSLGQTPYSYIVDLGQFQVVGASPEMLVQRQTNTMTSRPMAGTRRRGADASADLQLTQELLADPKEIAEHMMLLDLARNDLGRVAEVGSVQVKNILSVEYFSHVMHIVSTVTGLAPSQLSGLEVFKSTFPAGTLSGASKIRALEVIAQLEPHARGIYGGAIGCMDWHGGVDLAIAIRTGVLQAGILQVQAGAGVVQDSVAEREWQETIEKSRMMLLAAQLAQSWQQEMTVLEDPACI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2X8</accession>
    <name>A0A2S9H2X8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">LysM domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0949</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94328">
        <property type="protein sequence ID" value="PRC94328"/>
        <property type="gene ID" value="S2091_0949"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00118">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036779">
        <property type="entry name" value="LysM_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01476">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00257">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54106">
        <property type="entry name" value="SSF54106"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51782">
        <property type="entry name" value="LYSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LysM" evidence="1">
        <location>
            <begin position="150"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="244" mass="27323" checksum="95F6027CC581E4C8" modified="2018-07-18" version="1">MATSQHANGLDAWKDGIRKAAGDPKWDAHDAEIKSTLTTYTHHLIRQGYRQPNLSWQMIKAMVWVETGAGNDEWKIKPMQIGNRNDPGIDDFLANDKGAEIIVPPHLRIMLTRERIKHNSSYNIQAGIGYLLMRSAEYGFENTLLNTTVLSYTVKPGDSLDRIARTQGSTIATLKKLNPSAHILRPGQVLKYQKSTIKKVITGWSPITTGMIAIRYNKGDKNYAEKLEFALNVICNRKGASCSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2Z2</accession>
    <name>A0A2S9H2Z2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0948</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94327">
        <property type="protein sequence ID" value="PRC94327"/>
        <property type="gene ID" value="S2091_0948"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015765176" evidence="1">
        <location>
            <begin position="26"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="146" mass="16742" checksum="538A8B919CA0F3FC" modified="2018-07-18" version="1">MFTINRLTKFFILSFCVISPWLVFAADKPFTGVFEGQGRGCYGKLFIKTKTIEWNTPFTVCKQTPYTILEKDFSTKSPHIAYLLKNSSEKACGLQVIEVKFNPEYPDYWKAIGYPTIDDFYNKNDPNSDTLSCSIWVLKGSQLMGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H310</accession>
    <name>A0A2S9H310_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">HipA N-terminal domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_0990</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HipA Ser/Thr kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94369">
        <property type="protein sequence ID" value="PRC94369"/>
        <property type="gene ID" value="S2091_0990"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012893">
        <property type="entry name" value="HipA-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017508">
        <property type="entry name" value="HipA_N1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13657">
        <property type="entry name" value="Couple_hipA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07804">
        <property type="entry name" value="HipA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03071">
        <property type="entry name" value="couple_hipA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Couple_hipA" evidence="4">
        <location>
            <begin position="5"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="domain" description="HipA_C" evidence="3">
        <location>
            <begin position="146"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC94369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="434" mass="48678" checksum="DF34BBD93291F76B" modified="2018-07-18" version="1">MRQLNATLNEELVGVLSEDNNIWVFTYDPEWAASPSGFDLSPALSRSQLQHVDGSTVRSVQWYFDNLLPEEELRSALAKENKFDGSDAFSLLEYFGAESAGSLVLLPPGQQEPPISQTRELPDEALCQRIKNLPHATFAKNAPKRMSLAGAQHKLLVVYMDGKLHEPVGRTPSTHILKPNHQSADYPASVMNEYFTMRLASKLGLNVPPIYRHYTPEPVYIIQRFDRYTDPSGQTQRHHIIDTCQLLNKDRLFKYKDASIATLKAVISRCRNRVLATSRLYQWLVFNVLIANEDNHLKNLSFTVGQQGIDLSPFYDILSTGVYHTRAIANDRAAWDKVDMVIALGDVKSFSDVTRAAILQAGADLGLRPAACVRELDRQISKLPKAVEQMEAEIVKENATLNPETAKFLASEIRLIGVIKHIIVPEMINKASVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H362</accession>
    <name>A0A2S9H362_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 3">Pyrroline-5-carboxylate reductase</fullName>
            <shortName evidence="2">P5C reductase</shortName>
            <shortName evidence="2">P5CR</shortName>
            <ecNumber evidence="2 3">1.5.1.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">PCA reductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">proC</name>
        <name evidence="6" type="ORF">S2091_1043</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>L-proline + NAD(+) = 1-pyrroline-5-carboxylate + 2 H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:14105"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15893"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:60039"/>
            <dbReference type="EC" id="1.5.1.2"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 3">
            <text>L-proline + NADP(+) = 1-pyrroline-5-carboxylate + 2 H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:14109"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15893"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:60039"/>
            <dbReference type="EC" id="1.5.1.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 3">Amino-acid biosynthesis; L-proline biosynthesis; L-proline from L-glutamate 5-semialdehyde: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2 3">Belongs to the pyrroline-5-carboxylate reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.5.1.2" evidence="2 3"/>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94422">
        <property type="protein sequence ID" value="PRC94422"/>
        <property type="gene ID" value="S2091_1043"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00098">
        <property type="reaction ID" value="UER00361"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004735">
        <property type="term" value="F:pyrroline-5-carboxylate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055129">
        <property type="term" value="P:L-proline biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01925">
        <property type="entry name" value="P5C_reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028939">
        <property type="entry name" value="P5C_Rdtase_cat_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029036">
        <property type="entry name" value="P5CR_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000304">
        <property type="entry name" value="Pyrroline-COOH_reductase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11645">
        <property type="entry name" value="PTHR11645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03807">
        <property type="entry name" value="F420_oxidored"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14748">
        <property type="entry name" value="P5CR_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000193">
        <property type="entry name" value="Pyrrol-5-carb_rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00112">
        <property type="entry name" value="proC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00521">
        <property type="entry name" value="P5CR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 3" id="KW-0521">NADP</keyword>
    <keyword evidence="2 3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2 3" id="KW-0641">Proline biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F420_oxidored" evidence="4">
        <location>
            <begin position="1"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="domain" description="P5CR_dimer" evidence="5">
        <location>
            <begin position="149"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF14748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC94422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="263" mass="27860" checksum="6D244AEBD7B1BFA0" modified="2018-07-18" version="1">MASALIGGLCGTVSQPEDIHVVDVSPVCLSQLTERFGIKTSNQIDAQIAECDVVLLAVKPQQMREVAEQLVPYLKGQLIISIAAGIRALDLSRWLNGYPQIVRTMPNMPALINQGITGMYAMPVVSAEQRTIANAIMSAVGATVWLDNEALLDPLTAISGSGPAYVFYFIEAMQKAAQEMGLDQEQGRQLALATFLGASQLAAQSSEPAAVLRERVTSKGGTTYAALTSMEQSGVSNAIVTALKAAAERSSELGDEFGSEPSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3C2</accession>
    <name>A0A2S9H3C2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ABC-type antimicrobial peptide transport system ATPase component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_1092</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94471">
        <property type="protein sequence ID" value="PRC94471"/>
        <property type="gene ID" value="S2091_1092"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03255">
        <property type="entry name" value="ABC_MJ0796_LolCDE_FtsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017911">
        <property type="entry name" value="MacB_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-1278">Translocase</keyword>
    <feature type="domain" description="ABC transporter" evidence="7">
        <location>
            <begin position="5"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="41"/>
            <end position="48"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC94471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="242" mass="26489" checksum="F409F0A2DC7E29BB" modified="2018-07-18" version="1">MTELIRLHDIGKQYQMGGEIIAALDGINLTIQRNEYMAFIGSSGSGKSTMMNILGCLDTPSRGSYSLNGRNVASMSQAELAQTRNREIGFIFQSFNLLPRATALQNVMQPLIYRGIRPAERERRARQVLARVGLENRVDHLPNQLSGGQRQRVAIARALCGEPSILLADEPTGNLDSTTAADIMSLFDTLHSEGQTIIVVTHEPDIANHCQRTVRLSDGRVLTDTNTASTTALSPTEEIVRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3C8</accession>
    <name>A0A2S9H3C8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Efflux transporter, RND family, MFP subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1091</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94470">
        <property type="protein sequence ID" value="PRC94470"/>
        <property type="gene ID" value="S2091_1091"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006143">
        <property type="entry name" value="RND_pump_MFP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01730">
        <property type="entry name" value="RND_mfp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HlyD_D23" evidence="2">
        <location>
            <begin position="43"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="413" mass="44827" checksum="AB4F31CC8FB9E695" modified="2018-07-18" version="1">MKRKWLVFTGIACLFAVPFLLKLVHSETAQLVEVQKVAPREIKASILASGNLVFQEQALLSPEVIGKVRSVLVKEGDHVEAGQVVLTLDDQAYRADLAQQQALVRQGQIDIEHQQLSITNQTSQYQRKLDMQRLKMVSDSALDDARYAFDLSKIELRKSREGLQQAQAVLNQSMERLAKTNIRSPISGTVTSLDIKVGETAVASQIGIAGSSLMTIANTASLMAEVNVDEADIARIMLGQEVLIHTAAYPDTPLTGVVKTIPLSPKKDSGQTGTSLARNYSVKVSIANPDKLILHPGMTCRAEIYTATSGKSLAVPLQAVQSNNDQQTDVGADNKTKNKATVKIENYVFVLENGVSHKRVVKLGISDDTNQEIVAGLTQGDSVIIGPYKILRHLKPDEKLQASAANETAAVKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3D4</accession>
    <name>A0A2S9H3D4_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Glucose-6-phosphate 1-dehydrogenase</fullName>
            <shortName evidence="5">G6PD</shortName>
            <ecNumber evidence="5">1.1.1.49</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">zwf</name>
        <name evidence="9" type="ORF">S2091_0492</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>D-glucose 6-phosphate + NADP(+) = 6-phospho-D-glucono-1,5-lactone + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:15841"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:57955"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:61548"/>
            <dbReference type="EC" id="1.1.1.49"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5">Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 1/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the glucose-6-phosphate dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.49" evidence="5"/>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94489">
        <property type="protein sequence ID" value="PRC94489"/>
        <property type="gene ID" value="S2091_0492"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00115">
        <property type="reaction ID" value="UER00408"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004345">
        <property type="term" value="F:glucose-6-phosphate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006006">
        <property type="term" value="P:glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006098">
        <property type="term" value="P:pentose-phosphate shunt"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00966">
        <property type="entry name" value="G6PD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001282">
        <property type="entry name" value="G6P_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019796">
        <property type="entry name" value="G6P_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022675">
        <property type="entry name" value="G6P_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022674">
        <property type="entry name" value="G6P_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23429">
        <property type="entry name" value="PTHR23429"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02781">
        <property type="entry name" value="G6PD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00479">
        <property type="entry name" value="G6PD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000110">
        <property type="entry name" value="G6PD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00079">
        <property type="entry name" value="G6PDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00871">
        <property type="entry name" value="zwf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00069">
        <property type="entry name" value="G6P_DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="1 5" id="KW-0313">Glucose metabolism</keyword>
    <keyword evidence="2 5" id="KW-0521">NADP</keyword>
    <keyword evidence="3 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="G6PD_N" evidence="7">
        <location>
            <begin position="5"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="domain" description="G6PD_C" evidence="8">
        <location>
            <begin position="183"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="234"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="8"/>
            <end position="15"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="42"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="142"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="172"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 6">
        <location>
            <position position="176"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="210"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="229"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="334"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022526"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC94489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="486" mass="54191" checksum="3741BD38BAE567F3" modified="2018-07-18" version="1">MTTFVLFGGTGDLAKRKIIPALYSAFLNGRLDSNFTFVGAAREAISDDEFRERVAASISSHAKPDGVGTPEQLKSFLAKTLYSKIDARVDADFAALKNKIASPDSNATLFYLATGPDIFVPIVQQLSSHDLVGSQARVVLEKPLGRDAQSARDINQALRTYLKENQIYRIDHYLGKEMVQNLLALRFANSFLEPLWNRKWIHDVQISIAEQVGVEARGEFYDHTGALRDMVQNHLLQLLSIVAMEPPVNAAPDSIRDEKVKVLRALHKFTPDEVIKRTVRGQYRAGAVNGQPVVGYQNETGVPAHTRTETFVAIRAEIDSWRWAGVPFYLRTGKRMASRSAEITINFKPIPYSIFGTSQTNLRSNRLVISLQPEESVQLFLKAKEPGEGIRLSDVALNLDFAEASTSRRVEAYERLLLDAMHGDLTLFVRDDELGAAWDWVDPIMSTWQTDTEGLKSYIAGSWGPAASSYLLAQHGSTWGEEFVED</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3D7</accession>
    <name>A0A2S9H3D7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Amidases related to nicotinamidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0498</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94495">
        <property type="protein sequence ID" value="PRC94495"/>
        <property type="gene ID" value="S2091_0498"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.850">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000868">
        <property type="entry name" value="Isochorismatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036380">
        <property type="entry name" value="Isochorismatase-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00857">
        <property type="entry name" value="Isochorismatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52499">
        <property type="entry name" value="SSF52499"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Isochorismatase" evidence="1">
        <location>
            <begin position="17"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="214" mass="23366" checksum="8A51DE8C63EE9941" modified="2018-07-18" version="1">MSASAISAKPTKILKRALVVIDVQNEYFSGNLLVEYPDPNVSLKNVGLAMDVAHAAGVPILVVQHTAPQGAPIFQKGQPEWELHDIVKSRKHDHYVEKNLASIFSGTNVATWLKENEIDTLSIIGYMTQNCNASTIYQAMHDGYKVEVLNDATGAVPYSNEAGRATAEEIHRVFNVVFHSNFAAVVSTADWIQTVHADAPIAKGDVFTSNRNAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3F0</accession>
    <name>A0A2S9H3F0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Chorismate binding enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1084</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94463">
        <property type="protein sequence ID" value="PRC94463"/>
        <property type="gene ID" value="S2091_1084"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044249">
        <property type="term" value="P:cellular biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901576">
        <property type="term" value="P:organic substance biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005801">
        <property type="entry name" value="ADC_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001544">
        <property type="entry name" value="Aminotrans_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036038">
        <property type="entry name" value="Aminotransferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019999">
        <property type="entry name" value="Anth_synth_I-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043132">
        <property type="entry name" value="BCAT-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043131">
        <property type="entry name" value="BCAT-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015890">
        <property type="entry name" value="Chorismate_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11236">
        <property type="entry name" value="PTHR11236"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01063">
        <property type="entry name" value="Aminotran_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00425">
        <property type="entry name" value="Chorismate_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00095">
        <property type="entry name" value="ANTSNTHASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56322">
        <property type="entry name" value="SSF56322"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56752">
        <property type="entry name" value="SSF56752"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chorismate_bind" evidence="1">
        <location>
            <begin position="119"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="614" mass="67930" checksum="05AFF4DB458D9761" modified="2018-07-18" version="1">MSSFTLLDDSDASAAQPTSRLYTDLQQVLSCTDAAQFSFMLEQMQAALQQGLYAVAVFSYELGVELQGLDSGPAQPSSILLYRQCQHLSHEQVGSWLQQQSECVAEVAGIAGLRSSVDEDEFTRAIERIQRYIASGDTYQVNYTFRLHFTTYGSICALYRRLRERQSVPYGALIAMPDGSAMLSLSPELFVRHSQGKLSARPMKGTAAASNTCDATLNQQLNTQRSEHLSLDVKNRAENLMIVDLLRNDLGRIAQLGSVQVPKLFEVQRFNSVLQMTSSVTAQLRADVNLTDLFLAIYPCGSITGAPKIRTMQIIQEVETETRGIYTGAIGWFDPTQHSSYGIQNIPDFCLSVPIRTLHLQAPQANGNRRGVMGVGAGIVFDSVAADEYQECQLKARFLTDLPAQFALFETMYATKENGCRHVERHLQRLAKSTHYFGLPLHVSDIEQQLQTACAALPENIPHRLKLSVDGTGQIQIQSAVLAPLTMPVKVLFASAQQQTQNLWLQHKTTQRAEYDQAWQMAESQGAFDMLFCNERGELTEGGRTNLLVKIDGRWITPPLSAGVLPGVMRSVLMDDPAWALTERSISVELLMNAEEIAVCNALRGVLTAQLVLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3G5</accession>
    <name>A0A2S9H3G5_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Enoyl-[acyl-carrier-protein] reductase [NADH]</fullName>
            <ecNumber evidence="6">1.3.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">S2091_0521</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>a 2,3-saturated acyl-[ACP] + NAD(+) = a (2E)-enoyl-[ACP] + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:10240"/>
            <dbReference type="Rhea" id="RHEA-COMP:9925"/>
            <dbReference type="Rhea" id="RHEA-COMP:9926"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:78784"/>
            <dbReference type="ChEBI" id="CHEBI:78785"/>
            <dbReference type="EC" id="1.3.1.9"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.9" evidence="6"/>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94518">
        <property type="protein sequence ID" value="PRC94518"/>
        <property type="gene ID" value="S2091_0521"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00094"/>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004318">
        <property type="term" value="F:enoyl-[acyl-carrier-protein] reductase (NADH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016631">
        <property type="term" value="F:enoyl-[acyl-carrier-protein] reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd05372">
        <property type="entry name" value="ENR_SDR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014358">
        <property type="entry name" value="Enoyl-ACP_Rdtase_NADH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43159">
        <property type="entry name" value="PTHR43159"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000094">
        <property type="entry name" value="Enoyl-ACP_rdct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="5 6" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="6" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="5 6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="4 6 9" id="KW-0520">NAD</keyword>
    <keyword evidence="3 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="149"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="159"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="17"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="23"/>
            <end position="24"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="68"/>
            <end position="69"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="96"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="99"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="166"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR000094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000094-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000094-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000094-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC94518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="258" mass="27177" checksum="FFCC729940933F19" modified="2018-07-18" version="1">MNSTSTTLVGKKGLIIGVANAHSIAWGCAQAMHNAGAELALTWLNERTHTEIQPLAEQLGAALCMPLDVEQAGQLEAVFEAITQQWGKLDFVVHSIAFAPQKDLHGRVVDSSAQGFARAMDISCHSFIRVAKLAEPLMKNGGSLQTMSYLGADSVIANYGLMGPVKAALESTVRYLAAELGLSGIRVNAISPGALETRAASGIAHFDQLLDDAKQRSPMRQLTTIHEVGALSAFLASDAACSMTGGTLFVDGGMNILN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3J9</accession>
    <name>A0A2S9H3J9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0551</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94548">
        <property type="protein sequence ID" value="PRC94548"/>
        <property type="gene ID" value="S2091_0551"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13443">
        <property type="entry name" value="HTH_26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="19"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="82" mass="9145" checksum="B8949C12FA3917BC" modified="2018-07-18" version="1">MPILINLDVMLAKNKVKSKELALFVGITEQNLSLLKSGKVKGVRFDTLQKICERLNCQPGDILEYRAGPVIRKDAEEALESC</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3T6</accession>
    <name>A0A2S9H3T6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="10">MacB-like periplasmic core domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">S2091_0624</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94621">
        <property type="protein sequence ID" value="PRC94621"/>
        <property type="gene ID" value="S2091_0624"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025857">
        <property type="entry name" value="MacB_PCD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12704">
        <property type="entry name" value="MacB_PCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="21"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="317"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="361"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="403"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="domain" description="MacB_PCD" evidence="9">
        <location>
            <begin position="20"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="8">
        <location>
            <begin position="344"/>
            <end position="433"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF12704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC94621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="440" mass="48180" checksum="D81990340ADF5ECC" modified="2018-07-18" version="1">MYSYYLMLGWRSLRRNPILTGLMVLTLAVGIAASVSTLTILHVLSSNPIPHKSSNLLVPVMDNGPLDDYVPGEPNSPRKSSQMTYRDANNLLALGFGSNRTALYSVRMLVESPKRELGLIGVRGIATTSAYFPMFEVPFRYGSAWSAEDDKNAAKVVVLSQNTSEKFFGNDNPVGKQLRFQQQDFTIIGVLAPWSPLPHYTNLLSGKSAVVGEEEIYIPFNTAITNKFENNGNLSCSGPTGPGFQGVLDSECIWIQFWFETNSATQNSQLKDQLDAYTKDQKKLGRFPRQAPNGLFNVMQWMEYLKVVPNDSKLSTWLSFGFLALCLVNTVGLLLAKFSARAAEIGVRRALGASQADIFKQFLIETVVLGLVGGVLGLALSFLGLWGISHQTADLAVIAHMDLTMLAITFVLSVAASVLAGLLPTWRACRVTPAIQLKSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3U4</accession>
    <name>A0A2S9H3U4_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_0655</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94652">
        <property type="protein sequence ID" value="PRC94652"/>
        <property type="gene ID" value="S2091_0655"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013767">
        <property type="entry name" value="PAS_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00989">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="253"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="6">
        <location>
            <begin position="291"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="5">
        <location>
            <begin position="551"/>
            <end position="764"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC94652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="766" mass="86063" checksum="2936302E6268F006" modified="2018-07-18" version="1">MSSTTQKFVQSRWPWLAASLILTVALFVSSTLGWLWYADQRDAAARELSLDLLWLEQNVTQTLSDNEHMLDNWARDLQTPSAHSYADFLSLADGLMKENPALISIDYLNKNGQRVIGLPNYTERPAKLPPVNDPLITEAIQRCYTLKKPVFSRVIEQYAPLWVMVVPVSDEVSNEGVVLATYDLDQLLSLQVPWWFVQRYDLSLVDRDNKQLSPHDGSTIEVSRDVHKLNFGPDNSGLSLRASSHAREHSEGLLLWLSAAVVAFGLLIIWLLRLLQRWLRERQIAQQALSHELRFREAMEQSLVTGLLAFDKAGRIIYVNPALCNMLGLSAESLIGSSAPFPFWPQENLNECQAAHDAMLRGDNPDNGRRLNLMDADGTRLSVRLFASRLASPIVNGDNKQNGWMVSLYDTTELQKEREALASSREQLYAVLSGLDAAVYVSSLSDGRVLFRNRHHAALFRFDAEGDCCLICWPELMHGSELTSVEFRDRQSGRWYHLERRTILWVDNSPVLLDIATDISAKREAADTAQERDELLQHTARLANLAEFASGIAHELNQPLAAIANYSAAADAFLEAQPVQTAKVHEAVRRMGDESRRAGKIIHSMRSFIQKRAIRHDFHHLKELLTEPLALLAPLAQRLQVEIVLELLEEEITIECDAVMIEQVLFNLIRNALEAVAGSDQTDEGVIVRIERDDENVTVSVSDRGPGIQEPDKLFQPFYTTKSEGMGLGLAICRTVIESHGGRLWAEANVGGGARFSFRLRCNAFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3V4</accession>
    <name>A0A2S9H3V4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">NAD(P)-binding Rossmann-like domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0668</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94665">
        <property type="protein sequence ID" value="PRC94665"/>
        <property type="gene ID" value="S2091_0668"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="646" mass="70596" checksum="E05FCC201558754D" modified="2018-07-18" version="1">MNDRDKCEGITRRDLLQSLALAISVPGLLTSEQSAAQTSTSAQNIPNAASTVATQLHDAVSDYPPARTGLRGTHVGAFEVAHNLRDGHQPYPIEESGQHYDLVIVGAGISGLAAAWFYRQQRPHARILILDNHDDFGGHAKRNEFNLNGELHLMNGGTLSIQSPRPYSAVAESLLRSVGINAQVLNKRIQNRKFYENHGLTSGIFFDTETFGRDALIRKVAGHSWKQVLADAPLGPQARKDIARIEEDHIDYLPGLTSDQKKQRLSDISYRDFLLDIVKADPETIKFYQQRTHGEYCIGIEAVSALDCWGLDFPGFQGLGLAPGSIPRMGPTAGGFADTEGSVDVHLPDGGATVARSLVRSLIPAAIPGHTVEDLITAHVDYSMLDRPENTLHIRLNSIVVSAKNMAGQEGKPDAVRVEYVTAERGYAVHATQCVMACWNMVIPYLCPELPEPQKEALKSLAKAPLVYASVAIKNWKAFEKLGVSSIYSPGAYFYSVWLNEWLSIGKYHTPHSSDHPIVVHMVHTPCEPGQNGTDQLRIGRAKLLATSLETFQINIRTQLDAMLGKAGFDSSRDILAITVNRWPHGYAFEYDPMLGPPNAPGSEPFVIGRQRFGSIAIANSDSGGLAYMDSAIDQAHRAVSELLST</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4D5</accession>
    <name>A0A2S9H4D5_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 3 4">Single-stranded DNA-binding protein</fullName>
            <shortName evidence="2">SSB</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_0804</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homotetramer.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94801">
        <property type="protein sequence ID" value="PRC94801"/>
        <property type="gene ID" value="S2091_0804"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04496">
        <property type="entry name" value="SSB_OBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00984">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000424">
        <property type="entry name" value="Primosome_PriB/ssb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011344">
        <property type="entry name" value="ssDNA-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10302">
        <property type="entry name" value="PTHR10302"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00436">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002070">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00621">
        <property type="entry name" value="ssb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50935">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0227">DNA damage</keyword>
    <keyword evidence="2" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="2" id="KW-0234">DNA repair</keyword>
    <keyword evidence="2" id="KW-0235">DNA replication</keyword>
    <keyword evidence="1 2 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="102"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Important for interaction with partner proteins" evidence="2">
        <location>
            <begin position="159"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="121"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR002070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC94801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="164" mass="17887" checksum="F335FE67CEF924DC" modified="2018-07-18" version="1">MASVNKVIILGNLGRDPETRYMPSGDAMTTISIATTDSWKDKASGEKKETTEWHRVTFFGKLAEIAGQYLKKGSSVYVEGSLRTRKYTDKDGIEKYATDIKADSMQMLGGRPGAGSMDDGYDSQPSMQNSAPAPRQSAPAAQPQQRPASRPAPNFSDMDDDIPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4J0</accession>
    <name>A0A2S9H4J0_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 9">Adenylate kinase</fullName>
            <shortName evidence="7">AK</shortName>
            <ecNumber evidence="7 9">2.7.4.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">ATP-AMP transphosphorylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">ATP:AMP phosphotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Adenylate monophosphate kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">adk</name>
        <name evidence="11" type="ORF">S2091_0100</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7 9">
            <text>AMP + ATP = 2 ADP</text>
            <dbReference type="Rhea" id="RHEA:12973"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Purine metabolism; AMP biosynthesis via salvage pathway; AMP from ADP: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7 9">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7 9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="7">Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7 8">Belongs to the adenylate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.3" evidence="7 9"/>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94905">
        <property type="protein sequence ID" value="PRC94905"/>
        <property type="gene ID" value="S2091_0100"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00588">
        <property type="reaction ID" value="UER00649"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004017">
        <property type="term" value="F:adenylate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044209">
        <property type="term" value="P:AMP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01428">
        <property type="entry name" value="ADK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00235">
        <property type="entry name" value="Adenylate_kinase_Adk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006259">
        <property type="entry name" value="Adenyl_kin_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000850">
        <property type="entry name" value="Adenylat/UMP-CMP_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033690">
        <property type="entry name" value="Adenylat_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007862">
        <property type="entry name" value="Adenylate_kinase_lid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23359">
        <property type="entry name" value="PTHR23359"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05191">
        <property type="entry name" value="ADK_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00094">
        <property type="entry name" value="ADENYLTKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01351">
        <property type="entry name" value="adk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00113">
        <property type="entry name" value="ADENYLATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 7 8" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 7" id="KW-0545">Nucleotide biosynthesis</keyword>
    <keyword evidence="4 7 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ADK_lid" evidence="10">
        <location>
            <begin position="123"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="NMP" evidence="7">
        <location>
            <begin position="30"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="LID" evidence="7">
        <location>
            <begin position="122"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="10"/>
            <end position="15"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="31"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="36"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="57"/>
            <end position="59"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="85"/>
            <end position="88"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="92"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="123"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="132"/>
            <end position="133"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="156"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="167"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="203"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF05191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC94905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="218" mass="23740" checksum="459A98AFBA0ABB2D" modified="2018-07-18" version="1">MRLILLGAPGAGKGTQATFIKEKYNIPQISTGDMLRAAVKAGTEMGLAAKKVMDAGGLVSDDIIIGLVKDRLKEADCANGYLFDGFPRTTPQADAMKDAGVVIDYVLEIDVPDSAIVERMSGRRVHLVSGRTYHVKFNPPKVEGRDDVTGEELIQRDDDKEATVTKRLSVYHEQTEVLLGYYGEWAQSGRPGAPKYRKIAGVGAVEAIRDQAFKALEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4N8</accession>
    <name>A0A2S9H4N8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Succinylglutamate desuccinylase / Aspartoacylase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_0031</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94836">
        <property type="protein sequence ID" value="PRC94836"/>
        <property type="gene ID" value="S2091_0031"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007036">
        <property type="entry name" value="Aste_AspA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04952">
        <property type="entry name" value="AstE_AspA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC94836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="332" mass="36219" checksum="6203E422B8BF18FA" modified="2018-07-18" version="1">MSNLLDKTNVPTHHSHYFKSSTYTAPKSGPAIIITGAVHGNETCGTQAILRVMHEIETGQLQIKAGMVTFVPIANPLAYQRGERNGERNLNRKLIPTSEPAQFEDYVVNWLCPLLAQHDVLLDLHSFRSAGQPFVLIGPENNSGALEPFQYAEKEHALAIRLGVRRMVDGWLSTYADGVARRKAAATATTAAAPNHDPQFGIGTTEYMRSMGGYALTLECGQHSDASAPEVAYQAILNTLRHMEVLTGEAPQPAPKIEAIRMVEVVDKCHPDDSFSRPWCSFDALKKGDIIGSSHNGTPVLAAFDGYILFPSAQAEAGEEWFYLAKASSRSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H527</accession>
    <name>A0A2S9H527_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">S2091_0262</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95067">
        <property type="protein sequence ID" value="PRC95067"/>
        <property type="gene ID" value="S2091_0262"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00088">
        <property type="entry name" value="HPT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.160">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004105">
        <property type="entry name" value="CheA-like_dim"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036061">
        <property type="entry name" value="CheW-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002545">
        <property type="entry name" value="CheW-lke_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036641">
        <property type="entry name" value="HPT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008207">
        <property type="entry name" value="Sig_transdc_His_kin_Hpt_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01584">
        <property type="entry name" value="CheW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02895">
        <property type="entry name" value="H-kinase_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01627">
        <property type="entry name" value="Hpt"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00260">
        <property type="entry name" value="CheW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01231">
        <property type="entry name" value="H-kinase_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00073">
        <property type="entry name" value="HPT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47226">
        <property type="entry name" value="SSF47226"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50341">
        <property type="entry name" value="SSF50341"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50851">
        <property type="entry name" value="CHEW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50894">
        <property type="entry name" value="HPT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HPt" evidence="10">
        <location>
            <begin position="709"/>
            <end position="816"/>
        </location>
    </feature>
    <feature type="domain" description="HPt" evidence="10">
        <location>
            <begin position="1083"/>
            <end position="1186"/>
        </location>
    </feature>
    <feature type="domain" description="HPt" evidence="10">
        <location>
            <begin position="1330"/>
            <end position="1437"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="7">
        <location>
            <begin position="1606"/>
            <end position="1811"/>
        </location>
    </feature>
    <feature type="domain" description="CheW-like" evidence="9">
        <location>
            <begin position="1813"/>
            <end position="1948"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="8">
        <location>
            <begin position="1996"/>
            <end position="2112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="598"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="1514"/>
            <end position="1548"/>
        </location>
    </feature>
    <feature type="modified residue" description="Phosphohistidine" evidence="3">
        <location>
            <position position="756"/>
        </location>
    </feature>
    <feature type="modified residue" description="Phosphohistidine" evidence="3">
        <location>
            <position position="1129"/>
        </location>
    </feature>
    <feature type="modified residue" description="Phosphohistidine" evidence="3">
        <location>
            <position position="1377"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="4">
        <location>
            <position position="2045"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC95067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="2119" mass="232391" checksum="3CD4611ABD6EB7F8" modified="2018-07-18" version="1">MISSDATQNMQNKFDTGPLSWVMAETREALMHAKRALHDALEQSAESQSTLLKHAKIYLHQAHGALQMVDVDGVSKLSETIEVLLDRMADGQLSVEPGHVNPIEHALDAIQEYLDELVVSGVQQPVRLFPYYRNLLMIKGGDRVNPVDLFFPDLMAHAPLTLIADADHPKPKKASYTNIRKRFEAALLPFLKQADTDLLQASAKQMQELIAEVWAAQNSAQARSFWAVMHGFAELVADQRLFGEQNVKQLFGRINLQIRRLVEGASSIPESLLRDALFFIARAENLPPNAANVRNAYQLDGQVPANFETQHFGGIEPGALSISKERLAQIKTLWAKIANGEGALFEKFEQKMKDLADVGLKLKSPPLSKLLRELTGLTRHVMQNRPSAAFALEMATSLLFIESALDQISHLPADFSERADILAARLLSLVSGESLDESAPWLDEMSQKAQQRQTMTALVGEMQSSLRIVEKTLDEYFRAPENTADLVQIDPIMHQIAGALAILDQDDANLALVHTKDLIRQIAQSEQPVDSALHTKIAQNIGALSFLIEALQTQPDTAKNKFSFDSETGFFRSHFLDVPAPVQVAEEVGDVDLHATSATSPENVQVSTEHELAEQQKQSANLASSLLEEPHNADIQAQLLASLEQERSVARLLDDPNASERATHAIAALAQTDFDVSEPQMSNIISAVGTEPEAVAPMLPSHPPMPVGDEAIDAELLEVFLMEAEEVMACVNDTIPMSRNDPSNQEHLITLRRSFHTLKGSSRMVGLGAFGNAGWSVEQVMNSWLADAHSGTDDLYALLEKASEIMGAWVRDLNAMGTSDCNGKALIEAADRLKNGGAFSYQEVVEEPMPSTVHVPYEVHQAVSIEHHVFTDAVVEPMVDSLPSITPELVSGTEEIIASNVITIHGEQLAEPEPELKSEFDAEADADLGFEFELPTLQEAHPINPLVLPTEPVEELAEPEVLLSEFEFAINSPALLDEAHAETMHEVAEPLVAESLSEPFAEPANDPAIETPAEYSIDDLIEYSLEDSLAAPVETPVEAPIDAPIEVPVEAPITPLQEAKIIDFPTNSGYFPAFEDNVKKIGNIEIGVPLYNIYLAETDEIVRFLSQDFSEWRHEPHRPVTTHAVHAAHSLAGSSATVGFASLQQVAHALEMVLQRLERHPVLLLPGEFDTLDRCVACVKGMLHQFALAEMAAYKPEQILVLEQLLGILTDRAQPHEMDMPDSKFDADFDFDADFDADFDADFESDVEAVVATAPVDDFVDFLPEAVVTEPAADAESALVELDVSAPLTEEEILAPIVIPTAIIPEAPSVLAAPHHIDETKLVDVTTLPKDDLDADLLPIFLEEGSDLFPLIGETLRAWQAAPHDVEISQSMLRLLHTVKGSARMAGAMALGQHTHDMESLIENYMQAGVLPPAALENLLSYHDAAVALFDQLRNPGAAVAPVVAPAAAFDANQSALIEVPATSVAKASTPAVARAGAAPVANLNAAANVALVRVRADILDRLVNQAGEVSISRSRLENEVTTLRSSMLELNENVGRLRDQLREVEIQAETQISSRMAMSGEREFDPLEFDRFTRLQELTRMMAESVNDVSTVQANISKTVEGATDDLISQARLTRELQQDLMRVRMVPFASISERLYRITRQASKELDKRVNLDIRGTSVEIDRSVLEKMAGPFEHLLRNAIVHGIESREKRQAMGKNEIGEILVQIRQEGNEVVINFNDDGQGLDLQRIREKAQHSGLLAIDEEVTDSEAVNLIFQSGFSTAHEVTELAGRGIGMDVVRSEATALGGRVSVTSTPNQGSNFTIHLPLTLAVTQVVLLSSGGKTYAVPSVLVEQVQQLKAQALAAAYNEGAIIWQEQRVAMHYLSTVLADYNALPVAQQYTPIIIMRSGNERVALHVDQVIGNREVVVKNIGQQLARMIGISGATVLGSGDIVLILNPLPLAQKMEHDMLRAPRLLQENSENPNLSATNEQLGAVSETRHSATHQPVQGLRRHHVVMVVDDSLTVRKVTQRLLLREGYQVVLAKDGVDALQQLQSITPDVMLVDIEMPRMDGFDLTRNVRNDERLRHVPIIMITSRTADKHRNYAQELGVNAYFGKPYQEDVLLSAIAGYLPQENTVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H542</accession>
    <name>A0A2S9H542_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0238</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95043">
        <property type="protein sequence ID" value="PRC95043"/>
        <property type="gene ID" value="S2091_0238"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009781">
        <property type="entry name" value="DUF1345"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07077">
        <property type="entry name" value="DUF1345"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="36"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="75"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="108"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="194"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC95043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="216" mass="23970" checksum="7F74EC406DE91466" modified="2018-07-18" version="1">MIVQLVKSRPRLVIAFMSGTMLSLLLPMQWNLLSRVLLGWNAAVWAYLFLMLWLMVRATPAKVAQLAEQEDKADLAIVAIMSFAATASLVAIILELGSMKELTPAHKLLHYGVTGATVLGSWCFIATIFTFHYAKLYYRSSPQQRALRFPDANLQPNYWDFLYFSFTIAVAAQTSDVTLTSRAIRKTALAQSVLSFWFNMAILGLSINIAAGLVGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H564</accession>
    <name>A0A2S9H564_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glyoxalase-like domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0330</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95135">
        <property type="protein sequence ID" value="PRC95135"/>
        <property type="gene ID" value="S2091_0330"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041581">
        <property type="entry name" value="Glyoxalase_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18029">
        <property type="entry name" value="Glyoxalase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015721026" evidence="1">
        <location>
            <begin position="24"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="domain" description="VOC" evidence="2">
        <location>
            <begin position="41"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC95135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="162" mass="17752" checksum="10CB8B282A520E19" modified="2018-07-18" version="1">MKKIAISILFPALFLSLSGPSWSSDVTSESAPVETAGHITGVGGVFFKAKDPKALAAWYRDVLGMPLEVWGGAALRYDAPKHPSALIWNAFPASTKYFAPSTSQFMINYAVDDMDALISRLLAKGVTVLKRTDDDPNGRFAWILDPEDNKIELWEPKRTAPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5J0</accession>
    <name>A0A2S9H5J0_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Probable cytosol aminopeptidase</fullName>
            <ecNumber evidence="8">3.4.11.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Leucine aminopeptidase</fullName>
            <shortName evidence="8">LAP</shortName>
            <ecNumber evidence="8">3.4.11.10</ecNumber>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Leucyl aminopeptidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">pepA</name>
        <name evidence="10" type="ORF">S2091_0449</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>Release of an N-terminal amino acid, Xaa-|-Yaa-, in which Xaa is preferably Leu, but may be other amino acids including Pro although not Arg or Lys, and Yaa may be Pro. Amino acid amides and methyl esters are also readily hydrolyzed, but rates on arylamides are exceedingly low.</text>
            <dbReference type="EC" id="3.4.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 8">
            <text>Release of an N-terminal amino acid, preferentially leucine, but not glutamic or aspartic acids.</text>
            <dbReference type="EC" id="3.4.11.10"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="8">Binds 2 manganese ions per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the peptidase M17 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.1" evidence="8"/>
    <dbReference type="EC" id="3.4.11.10" evidence="8"/>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95254">
        <property type="protein sequence ID" value="PRC95254"/>
        <property type="gene ID" value="S2091_0449"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00433">
        <property type="entry name" value="Peptidase_M17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.220.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00181">
        <property type="entry name" value="Cytosol_peptidase_M17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011356">
        <property type="entry name" value="Leucine_aapep/pepB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043472">
        <property type="entry name" value="Macro_dom-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000819">
        <property type="entry name" value="Peptidase_M17_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023042">
        <property type="entry name" value="Peptidase_M17_leu_NH2_pept"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008283">
        <property type="entry name" value="Peptidase_M17_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11963">
        <property type="entry name" value="PTHR11963"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00883">
        <property type="entry name" value="Peptidase_M17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02789">
        <property type="entry name" value="Peptidase_M17_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00481">
        <property type="entry name" value="LAMNOPPTDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52949">
        <property type="entry name" value="SSF52949"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00631">
        <property type="entry name" value="CYTOSOL_AP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8 10" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 8" id="KW-0464">Manganese</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 8" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CYTOSOL_AP" evidence="9">
        <location>
            <begin position="368"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="300"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="374"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="288"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="293"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="311"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="370"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS00631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC95254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="521" mass="54106" checksum="F1C25C71C7A10D7A" modified="2018-07-18" version="1">MANCLSIKEEKHVDFSTKPLAANSNFSSSKTACIVVGIYENKKLSPEAEALNSQGAISAALKSGDITGKVGSTLVLRNLAGVAAERVVLVGLGSAPAAKAVTTLNNATFTKVAQATAQCLASLSAADALITLTLHAENLNAAIRSLVLALRASAYRCDGLKSKPEVITTGVAKVAFSIQSKDQASAKTSLTQSIALANGIALTKQLADLPGNFCTPTYLANTAKKIAAEFNAATFKISTEILDRKQCQALKMGSFLSVTNGSDEPPKFIVLKHMGGKAKDAPVVLVGKGITFDSGGISLKAGAGMDEMKYDMGGAASVLGTMRAIAELKLKLNVIAVIPSCENMPNGRATKPGDIVTSMSGQTIEILNTDAEGRLVLCDALTYVERFKPAAVVDVATLTGACITSLGHHNSGLFTRHDAVHDDLANELLAAGVDTGDTAWRMPIGEAYNEQLKSNFADVANIGGPAGGSITAACFLERFTKQYTWAHLDIAGTAWKSGAAKGATGRPVSLLTTFLINRASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5K5</accession>
    <name>A0A2S9H5K5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0457</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95262">
        <property type="protein sequence ID" value="PRC95262"/>
        <property type="gene ID" value="S2091_0457"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC95262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="72" mass="7954" checksum="0F4DEFBC13AE0C3E" modified="2018-07-18" version="1">MKIKQLASFQGEVVLFVFDDIGANWELVWRWRNVGRGNCCGSGVIIVEGPAIVEVVNIGGSMILKKRGLHQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GST8</accession>
    <name>A0A2S9GST8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative hydrolase of the alpha/beta superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4506</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000036">
        <property type="protein sequence ID" value="PRC90758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90758">
        <property type="protein sequence ID" value="PRC90758"/>
        <property type="gene ID" value="S2091_4506"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000801">
        <property type="entry name" value="Esterase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00756">
        <property type="entry name" value="Esterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015454815" evidence="1">
        <location>
            <begin position="23"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="282" mass="31282" checksum="1F525B90C9EAC711" modified="2018-07-18" version="1">MVIRSKLMSWFFFLMVPMTAMAADNIQPLVIGETFTVTSKILGEVRRINVYAPPGYYESTNESTQEKVPVLYMPDGGMAEDFLHVAGLVQVSVGNGTMRPYLLVGIENTQRRRDMTGPTENANDKKIAPQVGGSAAFRKFIRDELMPAINSRYRTTHESAIVGESLAGLFVMETLLLEPDLFDTYIAIDPTLGWNNENLSKIAGSILNTQSGMKKHLYLTSSGDGNPEVSQRFAEVLAKDAPAGLRWHYEKMPEEKHLTIYEPAALKAFRAELGPVPTSLPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSU4</accession>
    <name>A0A2S9GSU4_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Flagellar protein FliL</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_4531</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 8">Controls the rotational direction of flagella during chemotaxis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell inner membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the FliL family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000036">
        <property type="protein sequence ID" value="PRC90783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90783">
        <property type="protein sequence ID" value="PRC90783"/>
        <property type="gene ID" value="S2091_4531"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009425">
        <property type="term" value="C:bacterial-type flagellum basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071973">
        <property type="term" value="P:bacterial-type flagellum-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005503">
        <property type="entry name" value="FliL"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35091">
        <property type="entry name" value="PTHR35091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03748">
        <property type="entry name" value="FliL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9" id="KW-0966">Cell projection</keyword>
    <keyword evidence="8" id="KW-0145">Chemotaxis</keyword>
    <keyword evidence="9" id="KW-0969">Cilium</keyword>
    <keyword evidence="8" id="KW-0283">Flagellar rotation</keyword>
    <keyword evidence="9" id="KW-0282">Flagellum</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="27"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU364125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC90783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="177" mass="19514" checksum="CCE839C8B2D551AA" modified="2018-07-18" version="1">MSKPPPKPEAAAADAVVPETGSKKKKIIIIAVIVAVILASAGGGAMMFLGKKDPNKKDEKKSAEKSTPPVFLALDNFVVNVQSENGDKFLQAGITLQVKNEEQMTYYKGYMPQLRSRILLLLSSKAADELLTNEGKEKLSSDIIKQIQRPYNNEEPTPKEAEERKILGVYFTSFMIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSV9</accession>
    <name>A0A2S9GSV9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Bacterial export protein, family 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_4539</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FliR/MopE/SpaR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000036">
        <property type="protein sequence ID" value="PRC90791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90791">
        <property type="protein sequence ID" value="PRC90791"/>
        <property type="gene ID" value="S2091_4539"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006605">
        <property type="term" value="P:protein targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002010">
        <property type="entry name" value="T3SS_IM_R"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30065">
        <property type="entry name" value="PTHR30065"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01311">
        <property type="entry name" value="Bac_export_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00953">
        <property type="entry name" value="TYPE3IMRPROT"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="43"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC90791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="81" mass="8929" checksum="2BA83C3CB7A390F3" modified="2018-07-18" version="1">MPAFDSELERKYTNLPIIAALLVTNIALGILTRAAPQLNIFGIGFPITMTVGFLMLFIIIPYLALPLQKILEFGIQLAALR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GT13</accession>
    <name>A0A2S9GT13_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Fido domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_4438</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000034">
        <property type="protein sequence ID" value="PRC90857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90857">
        <property type="protein sequence ID" value="PRC90857"/>
        <property type="gene ID" value="S2091_4438"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025758">
        <property type="entry name" value="Fic/DOC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003812">
        <property type="entry name" value="Fido"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036597">
        <property type="entry name" value="Fido-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040198">
        <property type="entry name" value="Fido_containing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026287">
        <property type="entry name" value="SoFic-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13504">
        <property type="entry name" value="PTHR13504"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02661">
        <property type="entry name" value="Fic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13784">
        <property type="entry name" value="Fic_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038925">
        <property type="entry name" value="AMP-prot_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140931">
        <property type="entry name" value="SSF140931"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51459">
        <property type="entry name" value="FIDO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fido" evidence="4">
        <location>
            <begin position="116"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="197"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="69"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="197"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="201"/>
            <end position="208"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="202"/>
            <end position="208"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="239"/>
            <end position="240"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="239"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR038925-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR640198-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR640198-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC90857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="361" mass="41102" checksum="0E4347A6EEED968D" modified="2018-07-18" version="1">MAYDKDQPYNDLPLVPPTYELETKAVLKKAISATAALAELRGIGNQIPNQSMLIRAFVLQEARLSSEIENVVTTNDELYKAFAEVEGKFDSATKEVLRYENALWHGYQGMKDRPLLTTNLFIELVGIINQLDGLGIRTGGGTKLANPTTRETIYTPPEGEKVIRDKLANLEDFIHSPDDLDPLVRMAIMHYQFEAIHPFSDGNGRTGRIINILYLVMKGMIDIPVLYLSRYIIEHKAAYYQGLRDVTEKGAWESWILYMLDAVEQTARATSKKILDIRALLQEYVTVVQEKLPKIYTKDLVEVLFSQPYCRIRFLEQANIAKRQAASTYLQQLEGIGLLRSVKVGREVYYVNDRLYSILTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GT16</accession>
    <name>A0A2S9GT16_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">tRNA-dihydrouridine(20/20a) synthase</fullName>
            <ecNumber evidence="6">1.3.1.91</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">U20-specific dihydrouridine synthase</fullName>
            <shortName evidence="6">U20-specific Dus</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">tRNA-dihydrouridine synthase A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">dusA</name>
        <name evidence="10" type="ORF">S2091_4434</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>5,6-dihydrouridine(20) in tRNA + NAD(+) = H(+) + NADH + uridine(20) in tRNA</text>
            <dbReference type="Rhea" id="RHEA:53340"/>
            <dbReference type="Rhea" id="RHEA-COMP:13533"/>
            <dbReference type="Rhea" id="RHEA-COMP:13534"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
            <dbReference type="EC" id="1.3.1.91"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>5,6-dihydrouridine(20) in tRNA + NADP(+) = H(+) + NADPH + uridine(20) in tRNA</text>
            <dbReference type="Rhea" id="RHEA:53336"/>
            <dbReference type="Rhea" id="RHEA-COMP:13533"/>
            <dbReference type="Rhea" id="RHEA-COMP:13534"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
            <dbReference type="EC" id="1.3.1.91"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>5,6-dihydrouridine(20a) in tRNA + NAD(+) = H(+) + NADH + uridine(20a) in tRNA</text>
            <dbReference type="Rhea" id="RHEA:53348"/>
            <dbReference type="Rhea" id="RHEA-COMP:13535"/>
            <dbReference type="Rhea" id="RHEA-COMP:13536"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>5,6-dihydrouridine(20a) in tRNA + NADP(+) = H(+) + NADPH + uridine(20a) in tRNA</text>
            <dbReference type="Rhea" id="RHEA:53344"/>
            <dbReference type="Rhea" id="RHEA-COMP:13535"/>
            <dbReference type="Rhea" id="RHEA-COMP:13536"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 6 7">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the Dus family. DusA subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the dus family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.91" evidence="6"/>
    <dbReference type="EMBL" id="PUGF01000034">
        <property type="protein sequence ID" value="PRC90853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90853">
        <property type="protein sequence ID" value="PRC90853"/>
        <property type="gene ID" value="S2091_4434"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102264">
        <property type="term" value="F:tRNA-dihydrouridine20 synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd02801">
        <property type="entry name" value="DUS_like_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02041">
        <property type="entry name" value="DusA_subfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035587">
        <property type="entry name" value="DUS-like_FMN-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001269">
        <property type="entry name" value="DUS_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004653">
        <property type="entry name" value="DusA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018517">
        <property type="entry name" value="tRNA_hU_synthase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42907">
        <property type="entry name" value="PTHR42907"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01207">
        <property type="entry name" value="Dus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006621">
        <property type="entry name" value="Dus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00742">
        <property type="entry name" value="yjbN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01136">
        <property type="entry name" value="UPF0034"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6 7" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3 6 7" id="KW-0288">FMN</keyword>
    <keyword evidence="6" id="KW-0521">NADP</keyword>
    <keyword evidence="5 6 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 6 7" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="6" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="Dus" evidence="9">
        <location>
            <begin position="18"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="6 8">
        <location>
            <position position="103"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="20"/>
            <end position="22"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="73"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="142"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="174"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="214"/>
            <end position="216"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="236"/>
            <end position="237"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="site" description="Interacts with tRNA" evidence="6">
        <location>
            <position position="100"/>
        </location>
    </feature>
    <feature type="site" description="Interacts with tRNA; defines subfamily-specific binding signature" evidence="6">
        <location>
            <position position="186"/>
        </location>
    </feature>
    <feature type="site" description="Interacts with tRNA" evidence="6">
        <location>
            <position position="189"/>
        </location>
    </feature>
    <feature type="site" description="Interacts with tRNA; defines subfamily-specific binding signature" evidence="6">
        <location>
            <position position="306"/>
        </location>
    </feature>
    <feature type="site" description="Interacts with tRNA; defines subfamily-specific binding signature" evidence="6">
        <location>
            <position position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR006621"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR006621-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC90853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="335" mass="37591" checksum="59A55003F450D18A" modified="2018-07-18" version="1">MTSPLGKTPVLPSRRLSVAPMMDWTDRHCRQFHRHITRHTWLYTEMVTTGALLHGDVARHLDFAEIEHPIALQLGGSEPADLSKSAKLGEQWGYDEINLNCGCPSERVQRGAFGACLMAEPTLVADCVKAMRDAVSIDVTVKHRIGINDTNSYAFMRDFVGEIADAGCSTFIVHARNAILKGLSPKENREIPPLNYEYAYQLKRDFPALEIIVNGGIKTCAEIDLHLQHLDGVMLGREAYHNPYVMAEFDARYYQDAMPIKSRFEVLQAMLPYVQDQLDLYAQRGLKLNSITRHMLGLMTGLAGARSFRQMLSDSKQLASGRAELLLEAMAKVRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GT18</accession>
    <name>A0A2S9GT18_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phage capsid scaffolding protein (GPO) serine peptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4445</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000034">
        <property type="protein sequence ID" value="PRC90864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90864">
        <property type="protein sequence ID" value="PRC90864"/>
        <property type="gene ID" value="S2091_4445"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019069">
        <property type="term" value="P:viral capsid assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009228">
        <property type="entry name" value="Capsid_scaffold_GpO"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05929">
        <property type="entry name" value="Phage_GPO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="253"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="275" mass="29971" checksum="966AD019BA919FA6" modified="2018-07-18" version="1">MPTSKFFRVATEGATTDGRVIDRATITQLAQSFNPKTYGARIWMEHIRGMTADSIFKAYGDVVAVKADEVETDTGKKLALFAQISPTPDLIAMSKARQKIYTSLEINPKFSDTGLPYLVGLGITDSPASLGTDILTFSAQQGENSPFAARKQNPDNFYTEAVEITVEFDDKPTDPDTGKLTTTLKNLFKKITTSDAAQDARFAELSTAIETVAQHVVTELDSYASQLTQIATLEKTITDLHNNFTAFKQLMDTQDSNPDQRPPAIGGPGTILTDC</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GT59</accession>
    <name>A0A2S9GT59_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Tryptophan 2,3-dioxygenase</fullName>
            <shortName evidence="7">TDO</shortName>
            <ecNumber evidence="7">1.13.11.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Tryptamin 2,3-dioxygenase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Tryptophan oxygenase</fullName>
            <shortName evidence="7">TO</shortName>
            <shortName evidence="7">TRPO</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Tryptophan pyrrolase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Tryptophanase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">kynA</name>
        <name evidence="8" type="ORF">S2091_4405</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-tryptophan + O2 = N-formyl-L-kynurenine</text>
            <dbReference type="Rhea" id="RHEA:24536"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:57912"/>
            <dbReference type="ChEBI" id="CHEBI:58629"/>
            <dbReference type="EC" id="1.13.11.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
        <text evidence="7">Binds 1 heme group per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="7">Amino-acid degradation; L-tryptophan degradation via kynurenine pathway; L-kynurenine from L-tryptophan: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the tryptophan 2,3-dioxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.13.11.11" evidence="7"/>
    <dbReference type="EMBL" id="PUGF01000033">
        <property type="protein sequence ID" value="PRC90912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90912">
        <property type="protein sequence ID" value="PRC90912"/>
        <property type="gene ID" value="S2091_4405"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00333">
        <property type="reaction ID" value="UER00453"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004833">
        <property type="term" value="F:tryptophan 2,3-dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019441">
        <property type="term" value="P:tryptophan catabolic process to kynurenine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01972">
        <property type="entry name" value="T23O"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037217">
        <property type="entry name" value="Trp/Indoleamine_2_3_dOase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017485">
        <property type="entry name" value="Trp_2-3-dOase_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004981">
        <property type="entry name" value="Trp_2_3_dOase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10138">
        <property type="entry name" value="PTHR10138"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03301">
        <property type="entry name" value="Trp_dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140959">
        <property type="entry name" value="SSF140959"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03036">
        <property type="entry name" value="trp_2_3_diox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7 8" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="1 7" id="KW-0349">Heme</keyword>
    <keyword evidence="5 7" id="KW-0408">Iron</keyword>
    <keyword evidence="2 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7" id="KW-0823">Tryptophan catabolism</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="47"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="109"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="113"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="7">
        <location>
            <position position="236"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="250"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC90912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="278" mass="31847" checksum="97884410F07C8A3B" modified="2018-07-18" version="1">MTTTKPTDWHDAKLDFSKDMSYGDYLGLGQILSAQHPLSPNHNEMLFIIQHQTSELWIKLMLHELHAVRQQMRTGDLPPAFKMLSRVARIMDQLVHAWDVLATMTPPEYTAIRPYLGQSSGFQSYQYRELEFILGNKNATLMQVHLSAPENYAKLDAVLTTPSIYDEAILLMARSGLTIEANRLQQDWTLPMQSNASVQAAWTQVYKAPEQHWALYELAEKLVDLETSFRTWRFRHVTTVERIIGFKTGTGGTAGVSYLRKMLDVVLFPELFALRTEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GT98</accession>
    <name>A0A2S9GT98_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative enzyme of the cupin superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4334</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000032">
        <property type="protein sequence ID" value="PRC90933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90933">
        <property type="protein sequence ID" value="PRC90933"/>
        <property type="gene ID" value="S2091_4334"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008579">
        <property type="entry name" value="UGlyAH_Cupin_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05899">
        <property type="entry name" value="Cupin_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cupin_3" evidence="1">
        <location>
            <begin position="39"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="114" mass="12849" checksum="B9CE65B3C83E7E7B" modified="2018-07-18" version="1">MVTPYLRNPLAQTELIAWGVIPTMLEGTSHTSGKLLHKGPDGQSECGIWRCTPGKWICHVTRDEFCHFLAGRCTYVHESGEIIEITPDTAAFFPQDWKGVCTVHETVTKVYMIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTD6</accession>
    <name>A0A2S9GTD6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4273</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000031">
        <property type="protein sequence ID" value="PRC90977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90977">
        <property type="protein sequence ID" value="PRC90977"/>
        <property type="gene ID" value="S2091_4273"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC90977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="460" mass="49090" checksum="A7837E8BA6C49F05" modified="2018-07-18" version="1">MANVKETNQWVDGIYQLEKTDDVIGGEDGIDNRQAIQLASRTTFLKNHVEDLETGKKAAGKAIKLNTARTINIDGDAEGHAEFDGSENVTMTLTQKESGIKAGSYRQVTVDAKGRVTDGNNPTTLAGYEITDAASISYVEKFEAWVQDSLSNKAGGKGIILNWDEREGQPTWLHGGNSPGNCALYNPSNFAVRHAGTAGNATNADTAQVTFKINNGADHMAFNWHDPGGQTTYVWGSDNSNSARLSATKNLRVGHADTAGNAALWCGYGYRYEENPGQIPYYVLGVTATSKGQISIYNVSNLLAGKEDRFPAGTRMPFAQAAAPTGWTQVNDDSTNNRMLRVVNGGGGGTGGDHDPVINNVVPAHTHSFTTGVESADHTHYIQDPGHVHSVPVRARGSTGAGFSDSGDRITYTGYSNAAVTGIWNSGISANHTHSGSTDNGSSQTNWQARYIDMIICAKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GU28</accession>
    <name>A0A2S9GU28_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_4022</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="PUGF01000026">
        <property type="protein sequence ID" value="PRC91237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91237">
        <property type="protein sequence ID" value="PRC91237"/>
        <property type="gene ID" value="S2091_4022"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Response regulatory" evidence="6">
        <location>
            <begin position="6"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="5">
        <location>
            <begin position="162"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="4">
        <location>
            <position position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC91237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="403" mass="45384" checksum="FD023075E278F3E8" modified="2018-07-18" version="1">MNKNFVILIVDDNLNNRFSVRELLVRIPHTEIIEAASGEKSLLLTIERDVHLILLDVQMPGMDGYETANILQMTERTRDIPIIFLTAVFKAEEFVKRGYALGAVDYLTKPLDDNILLNRVRHYQHLHERERKLSETLVELRTTRENLLQVEKFSALGTMVAGVSHELNTPLGNAKMAASTLHDRIVEIKKNYDAGTMKRNQIEQFFIEGEEITALVHRALDRAVDLVLNFKQVAVDQTSEQRSTFDFATVIEETIATLLINFKHEPWQVVLKLPSGIEIDSYPGSLEQIIVNLVHNSIRHGFHGRDHGCITINAYREHLPNKLYDQIVLIFSDDGVGIAPENLNRVFDPFFTTRLGQGGSGMGLSVCYRITTVLLGGSIEVETSSGSGTTFKLTFPLTAPVMM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GU57</accession>
    <name>A0A2S9GU57_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Porphobilinogen deaminase</fullName>
            <shortName evidence="8">PBG</shortName>
            <ecNumber evidence="8">2.5.1.61</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Hydroxymethylbilane synthase</fullName>
            <shortName evidence="8">HMBS</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Pre-uroporphyrinogen synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">hemC</name>
        <name evidence="11" type="ORF">S2091_4052</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 8">Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>H2O + 4 porphobilinogen = hydroxymethylbilane + 4 NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:13185"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:57845"/>
            <dbReference type="ChEBI" id="CHEBI:58126"/>
            <dbReference type="EC" id="2.5.1.61"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>dipyrromethane</name>
            <dbReference type="ChEBI" id="CHEBI:60342"/>
        </cofactor>
        <text evidence="8">Binds 1 dipyrromethane group covalently.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; coproporphyrinogen-III from 5-aminolevulinate: step 2/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5 8">Monomer.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="8">The porphobilinogen subunits are added to the dipyrromethane group.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 8">Belongs to the HMBS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.61" evidence="8"/>
    <dbReference type="EMBL" id="PUGF01000026">
        <property type="protein sequence ID" value="PRC91267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91267">
        <property type="protein sequence ID" value="PRC91267"/>
        <property type="gene ID" value="S2091_4052"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00251">
        <property type="reaction ID" value="UER00319"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004418">
        <property type="term" value="F:hydroxymethylbilane synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018160">
        <property type="term" value="P:peptidyl-pyrromethane cofactor linkage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006782">
        <property type="term" value="P:protoporphyrinogen IX biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00260">
        <property type="entry name" value="Porphobil_deam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000860">
        <property type="entry name" value="HemC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022419">
        <property type="entry name" value="Porphobilin_deaminase_cofac_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022417">
        <property type="entry name" value="Porphobilin_deaminase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022418">
        <property type="entry name" value="Porphobilinogen_deaminase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036803">
        <property type="entry name" value="Porphobilinogen_deaminase_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11557">
        <property type="entry name" value="PTHR11557"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01379">
        <property type="entry name" value="Porphobil_deam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03900">
        <property type="entry name" value="Porphobil_deamC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001438">
        <property type="entry name" value="4pyrrol_synth_OHMeBilane_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00151">
        <property type="entry name" value="PORPHBDMNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54782">
        <property type="entry name" value="SSF54782"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00212">
        <property type="entry name" value="hemC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00533">
        <property type="entry name" value="PORPHOBILINOGEN_DEAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Porphobil_deam" evidence="9">
        <location>
            <begin position="50"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="domain" description="Porphobil_deamC" evidence="10">
        <location>
            <begin position="270"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="modified residue" description="S-(dipyrrolylmethanemethyl)cysteine" evidence="8">
        <location>
            <position position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004735"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00260"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF03900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC91267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="357" mass="38290" checksum="DBDF5D959C6AF0F8" modified="2018-07-18" version="1">MHPIAQSQLGLAVIKFGTKICNKSRIGLVCVTWKESVLTPMLPKSAPKKLIIATRESRLAMWQAEHVQARLQALYPECVIELLGMTTRGDQILDRALSKVGGKGLFVKELETAMLDGRADLAVHSLKDMPMDVPVGLQLAAVLERADPRDALVSNLYATLTDLPAGAVIGTSSLRRQAALMAAYPHLLIKPLRGNLDTRLRKLDQGDYAAIILAAAGLKRLGLPERIRAYLEPEQSLPSAGQGAMAIEIADNRPELAAWLAPLNHHVSALAVHAERAVSKAFGGSCQIPLAAYATITDDVMHLRAFVATPDGSKIARAEVCGNSLDGAQLSAQIIDQLQAQDAATILAQCLSVEDKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUJ0</accession>
    <name>A0A2S9GUJ0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Response regulator containing CheY-like receiver AAA-type ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">S2091_3924</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000024">
        <property type="protein sequence ID" value="PRC91379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91379">
        <property type="protein sequence ID" value="PRC91379"/>
        <property type="gene ID" value="S2091_3924"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002197">
        <property type="entry name" value="HTH_Fis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002078">
        <property type="entry name" value="Sigma_54_int"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025943">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025944">
        <property type="entry name" value="Sigma_54_int_dom_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02954">
        <property type="entry name" value="HTH_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00158">
        <property type="entry name" value="Sigma54_activat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01590">
        <property type="entry name" value="HTHFIS"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00676">
        <property type="entry name" value="SIGMA54_INTERACT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00688">
        <property type="entry name" value="SIGMA54_INTERACT_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50045">
        <property type="entry name" value="SIGMA54_INTERACT_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Response regulatory" evidence="9">
        <location>
            <begin position="13"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma-54 factor interaction" evidence="8">
        <location>
            <begin position="146"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="416"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="416"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="6">
        <location>
            <position position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC91379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="535" mass="58045" checksum="60B64CA0B3DD6148" modified="2018-07-18" version="1">MQQIKNPSASVPRILVVDDEAHIRELLEITLIRMGMDVDSAENLTIARQYFAQNNYALVLTDMRLPDGLGLELVEEVAKSNKNTPIAVITAFGSTDNAVIALKAGAFDYVSKPVALDQLRKLVNSALQVSHIKSSANHTVTNASRLLGQSQAMQDLRSQIGRLARSMAPVSICGESGSGKELAAREIHAQSARANKPFVAVNCGAIPEALMEAEFFGYRKGAFTGANEERDGFFQAANGGTLMLDEVADLPLAMQVKLLRAIQERAVRKIGATAEETADVRIISATHQNLEECVANKRFRQDLYYRLNVIELKLPSLRERLDDVALLSEGILQRLSGKAVTLSPDALNALLHYDFPGNVRELENILERALAFANDGIVELADLALKQAKSTLTPAGSFASVDMLLDVAEKNTADSVSVAPTPATAPTPATAPTPTQAATQAPAPLPEVPPIAVKEVPGQNTQTPVAASIPPGGFKHFDDELPKSLPAYLEQVEREIILRALQKTRYNKTQAAELLGVSFRQLRYQIQKLKIYEAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUK9</accession>
    <name>A0A2S9GUK9_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">50S ribosomal protein L27</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpmA</name>
        <name evidence="7" type="ORF">S2091_3936</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the bacterial ribosomal protein bL27 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000024">
        <property type="protein sequence ID" value="PRC91391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91391">
        <property type="protein sequence ID" value="PRC91391"/>
        <property type="gene ID" value="S2091_3936"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00539">
        <property type="entry name" value="Ribosomal_L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001684">
        <property type="entry name" value="Ribosomal_L27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018261">
        <property type="entry name" value="Ribosomal_L27_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15893">
        <property type="entry name" value="PTHR15893"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01016">
        <property type="entry name" value="Ribosomal_L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00063">
        <property type="entry name" value="RIBOSOMALL27"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00062">
        <property type="entry name" value="L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00831">
        <property type="entry name" value="RIBOSOMAL_L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00029549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00539"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC91391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="90" mass="9436" checksum="B902F6D6D8A161A9" modified="2018-07-18" version="1">MAHKKGGGTTRNGRDSESKRLGVKVYGGQAINAGGIIIRQRGTRVHPGENVGMGKDHTLFALIPGKVQFIIKGAKQNQYVTIVPAAAVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUM7</accession>
    <name>A0A2S9GUM7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative intracellular protease/amidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3835</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000023">
        <property type="protein sequence ID" value="PRC91420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91420">
        <property type="protein sequence ID" value="PRC91420"/>
        <property type="gene ID" value="S2091_3835"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002818">
        <property type="entry name" value="DJ-1/PfpI"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01965">
        <property type="entry name" value="DJ-1_PfpI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DJ-1_PfpI" evidence="2">
        <location>
            <begin position="24"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="225" mass="23945" checksum="B8AE7D11431E4920" modified="2018-07-18" version="1">MNILMVLTSHDKLGDTGAKTGFWLEEFAAPYYVFQKAGAKITLTSPLGGQPPLDPKSDDPASQTESTIRFKSDSAAQATLANTRKLSDISTNDYDAVFYPGGHGPLWDLVNDKLSIALIEVMLEAGKPVAAVCHAPGVLRYVNNPDGTSVLKGKAVTGFTNSEEQAVGLSKVVPFLVEDMLKENGANYSKLADWQPHVVTDGLLITGQNPASSEPAAQALLKMLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUP5</accession>
    <name>A0A2S9GUP5_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ribonucleoside-diphosphate reductase subunit beta</fullName>
            <ecNumber evidence="3">1.17.4.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_3921</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>[thioredoxin]-disulfide + a 2'-deoxyribonucleoside 5'-diphosphate + H2O = [thioredoxin]-dithiol + a ribonucleoside 5'-diphosphate</text>
            <dbReference type="Rhea" id="RHEA:23252"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="ChEBI" id="CHEBI:57930"/>
            <dbReference type="ChEBI" id="CHEBI:73316"/>
            <dbReference type="EC" id="1.17.4.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3 5">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
        <text evidence="3 5">Binds 2 iron ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 3">Genetic information processing; DNA replication.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the ribonucleoside diphosphate reductase small chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.17.4.1" evidence="3"/>
    <dbReference type="EMBL" id="PUGF01000024">
        <property type="protein sequence ID" value="PRC91376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91376">
        <property type="protein sequence ID" value="PRC91376"/>
        <property type="gene ID" value="S2091_3921"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00326"/>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004748">
        <property type="term" value="F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009263">
        <property type="term" value="P:deoxyribonucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01049">
        <property type="entry name" value="RNRR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.620.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012348">
        <property type="entry name" value="RNR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033909">
        <property type="entry name" value="RNR_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000358">
        <property type="entry name" value="RNR_small_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23409">
        <property type="entry name" value="PTHR23409"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00268">
        <property type="entry name" value="Ribonuc_red_sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000355">
        <property type="entry name" value="NrdB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="SSF47240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0235">DNA replication</keyword>
    <keyword evidence="3 5" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="218"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="160"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="122"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="153"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="156"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="226"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="260"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="263"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR000355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000355-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000355-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC91376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="381" mass="43791" checksum="B552D010A74C5C07" modified="2018-07-18" version="1">MLSWDEEVTTPTAPNQPDRAPEPVFTPAAAAVAEAPAAAEQIARRVNAADKRIINGTTDVNQLVPFKYKWAWDKYLAGCANHWMPQEINMQRDIELWKNPNGLTPDERRLVIRNLGFFVTADSLAANNIVLGTYRHITAPECRQYLLRQAFEEAIHTHAYQYIVESLGLDEGEVFNAYHEVASIRDKDEFLIPFIDALTNPEFKTGTPENDQTLLKSLIVFACLMEGLFFYVGFTQILALGRQNKMMGAAEQYQYILRDESMHCNFGIDLINTIKMENPHLWTVEFREEIKALFLQAVELEYRYAEDTMPRGVLGLNAPMFKGYLRFIANRRAQQIGLEALFPNEENPFPWMSEMIDLKKERNFFETRVIEYQTGGALSWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUS1</accession>
    <name>A0A2S9GUS1_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Mannose-1-phosphate guanylyltransferase</fullName>
            <ecNumber evidence="3">2.7.7.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_3874</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>alpha-D-mannose 1-phosphate + GTP + H(+) = diphosphate + GDP-alpha-D-mannose</text>
            <dbReference type="Rhea" id="RHEA:15229"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:57527"/>
            <dbReference type="ChEBI" id="CHEBI:58409"/>
            <dbReference type="EC" id="2.7.7.13"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the mannose-6-phosphate isomerase type 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.13" evidence="3"/>
    <dbReference type="EMBL" id="PUGF01000023">
        <property type="protein sequence ID" value="PRC91459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91459">
        <property type="protein sequence ID" value="PRC91459"/>
        <property type="gene ID" value="S2091_3874"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004475">
        <property type="term" value="F:mannose-1-phosphate guanylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000271">
        <property type="term" value="P:polysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006375">
        <property type="entry name" value="Man1P_GuaTrfase/Man6P_Isoase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001538">
        <property type="entry name" value="Man6P_isomerase-2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005835">
        <property type="entry name" value="NTP_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01050">
        <property type="entry name" value="MannoseP_isomer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00483">
        <property type="entry name" value="NTP_transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01479">
        <property type="entry name" value="GMP_PMI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5 9" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NTP_transferase" evidence="7">
        <location>
            <begin position="5"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="domain" description="MannoseP_isomer" evidence="8">
        <location>
            <begin position="316"/>
            <end position="466"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC91459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="478" mass="52588" checksum="AC575FE9DEC9732A" modified="2018-07-18" version="1">MRLVPTILCGGAGSRLWPVSREQHPKPFIRLADGQSLLQKAFLRGAELNGVDEILTVTNRELFFKTEDEYREINQAKLATSYILEPFGRNTAAAIAAAALHISKKHGPDTLMLVLAADHLIADQAAFEQAVSEAIALAKREKIVTFGIQPDAPETGYGYIEASGNKVLRFVEKPSLATAQTYLDSGNFLWNSGMFCFMAGTILQAMEQHCPEILASTKVCMEQSRIAQADGFSQLELDADSFAAIPDNSIDYAVMEKSNHVAVVPCDIGWNDIGSWDSLGNLTVPDEQGNRLDGQTMLHKVENCYIQSKGRMVGVVGVSNLIIVDTPDALLVVDKSHTQDVKHIYAALKAKGHTAHKSHLTVHRPWGTYTVLEEGPGFKIKRIEVKPGASLSLQMHHHRSEHWIVVNGMAKVLNGDHEFLVSVNESTYIPAGHMHRLENPGVINLVMIEVQSGAYLGEDDIVRFQDKYGRCQVGQAQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUW2</accession>
    <name>A0A2S9GUW2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fimbrial protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3795</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000022">
        <property type="protein sequence ID" value="PRC91517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91517">
        <property type="protein sequence ID" value="PRC91517"/>
        <property type="gene ID" value="S2091_3795"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009289">
        <property type="term" value="C:pilus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007155">
        <property type="term" value="P:cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1090">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000259">
        <property type="entry name" value="Adhesion_dom_fimbrial"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036937">
        <property type="entry name" value="Adhesion_dom_fimbrial_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008966">
        <property type="entry name" value="Adhesion_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00419">
        <property type="entry name" value="Fimbrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49401">
        <property type="entry name" value="SSF49401"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015684100" evidence="1">
        <location>
            <begin position="33"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="domain" description="Fimbrial" evidence="2">
        <location>
            <begin position="199"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="336" mass="35772" checksum="8B8567D93D75D52D" modified="2018-07-18" version="1">MLQLAIKKYRLKYGVYTLFLVMCLVCAGQAQATAPECTWTSVQLSPQITTLEVTPIVGNVPYRGELRVDYSCFFYGAGSIAITPNIGGAGGKGMPLYWTTGLWIVATFVPSTTNTLGSSCWSNGGGIAAPDYAVVTLRSDRRQTCTGVLTQPFRIEVRSTPVAGTISKSNANSKYRSWVNIHGSKPPFGDLPADIPVSAAICTLSTPSMVVRLPSTTNTLLSVPGAVAGLTPFTISLRGCNGSGRTYFARASWSFIQGVSDNVIANTATTNPAANVQVQMLDSQNKPIVNGKRTDLAKIVSGQNAYDITYHAQYYAKGAAGAGKVEAVAYYIISYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUX5</accession>
    <name>A0A2S9GUX5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3789</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000022">
        <property type="protein sequence ID" value="PRC91511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91511">
        <property type="protein sequence ID" value="PRC91511"/>
        <property type="gene ID" value="S2091_3789"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015616582" evidence="1">
        <location>
            <begin position="27"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="236" mass="26816" checksum="5E096DE5BA9EB8D1" modified="2018-07-18" version="1">MSYTFRALSILAASLVASLLMNVARAEQLGEHPVLPTECQIALRIVTSPEYLQKNHSKIPELKNLDEAGMVTAMTNSLMESIKNAPDQEQFCATKIRQNLAYSSAYHFPKQCVDFLPLLKKSFEDRVAFKTDRSDSAQQKMNNAIVEMLVLDETDPAKLVQRCDVGIQVMQVNLNDKHLREKYPLPAACEVFFADMEKAMILPSQFETIQRQRVIFSIENKDTPERLDEICDEISK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GV07</accession>
    <name>A0A2S9GV07_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Patatin phospholipase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_3819</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000022">
        <property type="protein sequence ID" value="PRC91541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91541">
        <property type="protein sequence ID" value="PRC91541"/>
        <property type="gene ID" value="S2091_3819"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021095">
        <property type="entry name" value="DUF3734"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002641">
        <property type="entry name" value="PNPLA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12536">
        <property type="entry name" value="DUF3734"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01734">
        <property type="entry name" value="Patatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="SSF52151"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51635">
        <property type="entry name" value="PNPLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="1 2" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PNPLA" evidence="4">
        <location>
            <begin position="37"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXGXXG" evidence="2">
        <location>
            <begin position="41"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXSXG" evidence="2">
        <location>
            <begin position="68"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="DGA/G" evidence="2">
        <location>
            <begin position="228"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="2">
        <location>
            <position position="70"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC91541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="399" mass="44179" checksum="B012D954C9B51C67" modified="2018-07-18" version="1">MTSPRKKTPAAAPSSKSTVKSPRHNHPPALDHEHIVLVLQGGGALGAYQAGVFEALAKIPSEPNWVAGVSIGSINAALIVGNEPHRRVARLQEFWELVTSRSNMVAPMFGQQWSTLHQMGASMAASFGVPGFYKPRVPPPMFQPEGTDAAISYYDTTPLRETLERLIDFDLINSGRVRLSLGAVNVRTGNSEYFDNTKQIIGPDHVMASGALPPAFAPIMIDGEPYWDGGIVSNTPLQYVLDNRGLKKTMAVQVDLFSARGAMPLNMGSVLSRQKDIQYSSRTRMGTDKAAELQRSKQAVQRLIAKLPASMHNDPEVKHLMGATRTAHLDIVHLIYRQDRYELESKDYEFSRPTMQAHWEAGLRDMQRTLDHPDWLQMASENDGVTVYDLAHTHCSDKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GV38</accession>
    <name>A0A2S9GV38_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">D-aminoacyl-tRNA deacylase</fullName>
            <shortName evidence="1">DTD</shortName>
            <ecNumber evidence="1">3.1.1.96</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Gly-tRNA(Ala) deacylase</fullName>
            <ecNumber evidence="1">3.1.1.-</ecNumber>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">dtd</name>
        <name evidence="2" type="ORF">S2091_3684</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a D-aminoacyl-tRNA + H2O = a D-alpha-amino acid + a tRNA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13953"/>
            <dbReference type="Rhea" id="RHEA-COMP:10123"/>
            <dbReference type="Rhea" id="RHEA-COMP:10124"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:59871"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:79333"/>
            <dbReference type="EC" id="3.1.1.96"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>glycyl-tRNA(Ala) + H2O = glycine + H(+) + tRNA(Ala)</text>
            <dbReference type="Rhea" id="RHEA:53744"/>
            <dbReference type="Rhea" id="RHEA-COMP:9657"/>
            <dbReference type="Rhea" id="RHEA-COMP:13640"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78522"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="1">A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the DTD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.96" evidence="1"/>
    <dbReference type="EC" id="3.1.1.-" evidence="1"/>
    <dbReference type="EMBL" id="PUGF01000021">
        <property type="protein sequence ID" value="PRC91568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91568">
        <property type="protein sequence ID" value="PRC91568"/>
        <property type="gene ID" value="S2091_3684"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051499">
        <property type="term" value="F:D-aminoacyl-tRNA deacylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106026">
        <property type="term" value="F:Gly-tRNA(Ala) hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043908">
        <property type="term" value="F:Ser(Gly)-tRNA(Ala) hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019478">
        <property type="term" value="P:D-amino acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00563">
        <property type="entry name" value="Dtyr_deacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.80.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00518">
        <property type="entry name" value="Deacylase_Dtd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003732">
        <property type="entry name" value="Daa-tRNA_deacyls_DTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023509">
        <property type="entry name" value="DTD-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10472">
        <property type="entry name" value="PTHR10472"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02580">
        <property type="entry name" value="Tyr_Deacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69500">
        <property type="entry name" value="SSF69500"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00256">
        <property type="entry name" value="TIGR00256"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="1" id="KW-0820">tRNA-binding</keyword>
    <feature type="short sequence motif" description="Gly-cisPro motif, important for rejection of L-amino acids" evidence="1">
        <location>
            <begin position="140"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00518"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="161" mass="17353" checksum="11AC8243F4D24687" modified="2018-07-18" version="1">MIALIQRVSHAQVAVAGNVIGQIEQGLLVLLCAERDDSAKEAQALCEKLLKYRVFSDAQGKMNLSVRDIAGGILLVPQFTLAADTNSGTRPSFTPAAAPALAQELFNHFVALTKAQYPHDGKVATGQFGADMQVSLCNDGPVTFWLECKVVKKTLEEQTHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GV70</accession>
    <name>A0A2S9GV70_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA helicase</fullName>
            <ecNumber evidence="3">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_3729</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O = ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the helicase family. UvrD subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="3"/>
    <dbReference type="EMBL" id="PUGF01000021">
        <property type="protein sequence ID" value="PRC91613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91613">
        <property type="protein sequence ID" value="PRC91613"/>
        <property type="gene ID" value="S2091_3729"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013986">
        <property type="entry name" value="DExx_box_DNA_helicase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014017">
        <property type="entry name" value="DNA_helicase_UvrD-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000212">
        <property type="entry name" value="DNA_helicase_UvrD/REP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014016">
        <property type="entry name" value="UvrD-like_ATP-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11070">
        <property type="entry name" value="PTHR11070"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00580">
        <property type="entry name" value="UvrD-helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13361">
        <property type="entry name" value="UvrD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51198">
        <property type="entry name" value="UVRD_HELICASE_ATP_BIND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51217">
        <property type="entry name" value="UVRD_HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 9" id="KW-0347">Helicase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UvrD-like helicase ATP-binding" evidence="7">
        <location>
            <begin position="6"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="domain" description="UvrD-like helicase C-terminal" evidence="8">
        <location>
            <begin position="284"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="27"/>
            <end position="34"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC91613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="765" mass="85200" checksum="4F4815085220A03B" modified="2018-07-18" version="1">MQNLLHNLNPEQHAAVTLPAESALILAGAGSGKTRVLTTRIAWLIQTGQISPSGLMAVTFTNKAAKEMQARLSAMLPINTRSMWIGTFHGLCNRLLRAHHKDASLPQTFQILDSQDQLSMVKRILKANQIDDDKYPPRTVVYFINSAKEQGLRAAKVVTHDPISRQLAEIYGIYEQQCQRDGVVDFAELLLRTVELLASNQPLREHYQARFKHILVDEFQDTNDLQYRWIKLMAGSKAAVLAVGDDDQSIYAFRGANVGNMASFEREFQVQNRIKLEQNYRSHGHILDSANALISNNTERLGKNLRTDAGLGEVIRIQEASSDREEAQWMVEQIKDLTRQGISSDQIALLYRSNAQSRVIEHALFSANLPYRVYGGLRFFERAEIKHAIAYLQLMDNPHNDSAFLRVMNFPTRGIGAKGQETLQDTARQHGISLYAAVPYLAGKAGSTLGAFVKLIEAARFETQMLPLPELVQRVLELSTLITHYQSEKEGADRVENLEQLVSAAALFISEEGFANDAPALMGPASTVQTALVQGDGMEIMDADAALATLMSPLSAFLSHASLEAGDNQAQVGQDALQLMTVHSAKGLEFDAVFITGLEEGLFPHENSAKETNGIEEERRLMYVAITRARQRLFLSFAQTRMLHGQIRYNTKSRFLNELPDENVKWLTPQIKQNWFAPPKSAWDSDTSYSGNSSFQAKPVNPSHHSIIPTNADGWRIGLSVKHAKFGEGIIIKLEGSGTNCRAHIQFYKLGLKVLDLNIAKLEKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVD5</accession>
    <name>A0A2S9GVD5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">LysR substrate binding domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3742</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000021">
        <property type="protein sequence ID" value="PRC91626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91626">
        <property type="protein sequence ID" value="PRC91626"/>
        <property type="gene ID" value="S2091_3742"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="312" mass="35635" checksum="E666F87CA0B20DF3" modified="2018-07-18" version="1">MDTKWLEDFISLAETHSFSRSAELRHVTQPAFSRRIQSLEAWLGADLIDRTSYPTKLTSAGEVFYEQAIEMLGQISNARALMRNKRSTQQTVVDFAVPHTLSLTYMPKWLTQLESSFGHLNSRLLALNVHDAVMALVEGGCDLMLCYHHPRQPLQLDHSQYEMMVMGVEALRAYARCDAHGVPDFILPGDSENPLPFLAYANNAYLDRMVDVILSDTPTPMHLDKCYETDMAEGLKMMALEGRGIAFLPESSVARELKRKQLARADNGVASWEVEMEIRLYRERPSAQRPGKPLVNRLWEFLMHQHDAKKRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVH1</accession>
    <name>A0A2S9GVH1_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">2-isopropylmalate synthase</fullName>
            <ecNumber evidence="3">2.3.3.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Alpha-IPM synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Alpha-isopropylmalate synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">leuA</name>
        <name evidence="5" type="ORF">S2091_3642</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>3-methyl-2-oxobutanoate + acetyl-CoA + H2O = (2S)-2-isopropylmalate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:21524"/>
            <dbReference type="ChEBI" id="CHEBI:1178"/>
            <dbReference type="ChEBI" id="CHEBI:11851"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="EC" id="2.3.3.13"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid biosynthesis; L-leucine biosynthesis; L-leucine from 3-methyl-2-oxobutanoate: step 1/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.3.13" evidence="3"/>
    <dbReference type="EMBL" id="PUGF01000020">
        <property type="protein sequence ID" value="PRC91704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91704">
        <property type="protein sequence ID" value="PRC91704"/>
        <property type="gene ID" value="S2091_3642"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00048">
        <property type="reaction ID" value="UER00070"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003852">
        <property type="term" value="F:2-isopropylmalate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009098">
        <property type="term" value="P:leucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07942">
        <property type="entry name" value="DRE_TIM_LeuA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00572">
        <property type="entry name" value="LeuA_type2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013709">
        <property type="entry name" value="2-isopropylmalate_synth_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002034">
        <property type="entry name" value="AIPM/Hcit_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005668">
        <property type="entry name" value="IPM_Synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036230">
        <property type="entry name" value="LeuA_allosteric_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039371">
        <property type="entry name" value="LeuA_N_DRE-TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000891">
        <property type="entry name" value="PYR_CT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00682">
        <property type="entry name" value="HMGL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08502">
        <property type="entry name" value="LeuA_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00917">
        <property type="entry name" value="LeuA_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110921">
        <property type="entry name" value="SSF110921"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00970">
        <property type="entry name" value="leuA_yeast"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00815">
        <property type="entry name" value="AIPM_HOMOCIT_SYNTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00816">
        <property type="entry name" value="AIPM_HOMOCIT_SYNTH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50991">
        <property type="entry name" value="PYR_CT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2 3" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="3" id="KW-0432">Leucine biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pyruvate carboxyltransferase" evidence="4">
        <location>
            <begin position="31"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC91704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="571" mass="64282" checksum="2192C9BE4A71D629" modified="2018-07-18" version="1">MLNHPEKKYKRFQAIALPDRTWPNRLITAPPIWMSTDLRDGNQSLIEPMSVAKKLKMFQQLVKIGFKEIEVAFPSASDTDFDFVRSLIEQNLIPDDVTIEILTQSREDLIRRSVESLRGARRAIVHLYNPIAENFRRIVFNADRVEIKELAMQGTRLIKEITQTMPETEWVFQYSPETFSAAEPDFALEICDAVSAIWQPSAEQKMIINLPATVEMSTPNIYADQIEWMHRHLARREQIILSIHPHNDRGTAVAAAELAVMAGAQRVEGCLFGNGERTGNVDLVTLALNLYSQGIHPGLDFSDIDEVRSVVEYCNQLPVHPRHPYAGDLVFTAFSGSHQDAIKKGLAQQQPNTWWEVPYLPVDPDDLNRGYDAVIRVNSQSGKGGVSYILQQEHGIDLPRRLQIEFSRVIQRYTDQTGKEATADIIYHLFKTEYLDIEQPYRYRSHNCSNNPLQSFESDASLVEIDIVLEHQQQVRQILGCGNGPIEAFINGLELEMQVVDYHEHALGSGAQAEAICYMELKIGQHRPFFGIGIDRNSSVAALKSIVNGLNRGGVELGADGLLIASVEVLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVK3</accession>
    <name>A0A2S9GVK3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Acyl-CoA dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_3507</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000019">
        <property type="protein sequence ID" value="PRC91752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91752">
        <property type="protein sequence ID" value="PRC91752"/>
        <property type="gene ID" value="S2091_3507"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003995">
        <property type="term" value="F:acyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006089">
        <property type="entry name" value="Acyl-CoA_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="SSF47203"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="SSF56645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00073">
        <property type="entry name" value="ACYL_COA_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA_dh_N" evidence="7">
        <location>
            <begin position="19"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_M" evidence="6">
        <location>
            <begin position="135"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_1" evidence="5">
        <location>
            <begin position="239"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC91752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="391" mass="42831" checksum="22BFF2F8590696C7" modified="2018-07-18" version="1">MSKVAFHWDDPLLLNAQLTDEERMVRDAAQAYCSERLAPRVLEAFRHEQTDPAIFREMGELGLLGSTIPVEYGGAGMNYVCYGLVAREVERIDSGYRSMMSVQSSLVMVPINEFGSEAQKQKYLPKLATGEYIGCFGLTEPNHGSDPGSMVTRAKSVPGGYALSGSKMWITNSPIADVFVVWAKTDDGRIRGFILEKGWKGLTAPAIHGKVGLRASITGEIVMDEVFVPEENLMPNVEGLKGPFTCLNSARFGIAWGALGAAEFCWHMARQYTMDRKQFGRPLAANQLIQKKLADMQTEITLALQGCLRLGRMKDEGTAAVEITSIMKRNSCGKSLDIARMARDMLGGNGISDEFGIARHLVNLEVVNTYEGTHDIHALILGRAQTGIAAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVK9</accession>
    <name>A0A2S9GVK9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphatidylserine/phosphatidylglycerophosphate/ cardiolipin synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3499</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000019">
        <property type="protein sequence ID" value="PRC91744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91744">
        <property type="protein sequence ID" value="PRC91744"/>
        <property type="gene ID" value="S2091_3499"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019637">
        <property type="term" value="P:organophosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025202">
        <property type="entry name" value="PLD-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001736">
        <property type="entry name" value="PLipase_D/transphosphatidylase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13091">
        <property type="entry name" value="PLDc_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00155">
        <property type="entry name" value="PLDc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50035">
        <property type="entry name" value="PLD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PLD phosphodiesterase" evidence="1">
        <location>
            <begin position="172"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="domain" description="PLD phosphodiesterase" evidence="1">
        <location>
            <begin position="418"/>
            <end position="445"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="532" mass="59678" checksum="C34FEA3028E6AE16" modified="2018-07-18" version="1">MILISKLYYAAALLTVVILGGCASLPPGADFPKNTSTAFEHPENTLLGKNFDKAAHANAGNSGFRIIPVGADGFLMRMQMIKAAEHTLDLQYYIFHGDETGRLLTGAILSAADRGVRVRILIDDGETVDGDEQISVLEAHPSIEIRIFNPFNYRGHIQFFRATEFMFNAARLDYRMHNKLLVIDNSIALMGGRNIGDQYFQIDPESQFADDDLFAAGPITQHLSMTFDEYWNNALSIPVKALSSETHSLLALNDHRQELKEESRQLKADGVDYVKQIATGEPFNGIISGRLPLIWAHAQLVYDSPDKKKVESGAMVGRLMQREVANATIEVQSELLMITPYLIPGKEGMQLFKDLRQRHVHVRILTNSLESSAMLLAQAGYMHYRKPLLEDGVELYEIRALLENSKGSGQTPVISRYGNYSLHGKLFVLDRKRLFIGSMNFDQRSMHLNTEIGLIIDSPELAQQVAARFEAMVQPGNAYRLTLSTDNAASQNIVWHTQINKEPVEYDIEPARTNWQRFKVTILSLLPLDSEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVL7</accession>
    <name>A0A2S9GVL7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Heavy metal translocating P-type ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_3517</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000019">
        <property type="protein sequence ID" value="PRC91762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91762">
        <property type="protein sequence ID" value="PRC91762"/>
        <property type="gene ID" value="S2091_3517"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019829">
        <property type="term" value="F:ATPase-coupled cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00371">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006121">
        <property type="entry name" value="HMA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036163">
        <property type="entry name" value="HMA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027256">
        <property type="entry name" value="P-typ_ATPase_IB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00941">
        <property type="entry name" value="CDATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55008">
        <property type="entry name" value="SSF55008"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="SSF81653"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="SSF81665"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01525">
        <property type="entry name" value="ATPase-IB_hvy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50846">
        <property type="entry name" value="HMA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-1278">Translocase</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="177"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="380"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="412"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="716"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="742"/>
            <end position="761"/>
        </location>
    </feature>
    <feature type="domain" description="HMA" evidence="8">
        <location>
            <begin position="71"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="17"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC91762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="768" mass="81230" checksum="578E8A17DE578E9E" modified="2018-07-18" version="1">MANYLQIKSKHSHGSNCNHGHSHDHGHDHKHEEKQEHKHDHGAHAGRACSAGAPVTFTGLAAQIAVDGGVRTAMRITQMDCPTEEGLIRKKLGGMAQVKSMEFNLMQRVLTVVHAPEALDSVIQAIRSLGFEPELPGASGELAAEVQAPAKAWWPLALAVVAAIGAEASSWLAWPAALGIALALLAIGACGLSTYKKGWIALRNGNLNINALMSIAVTGAALIGQWPEAAMVMVLFTIAELIEAKSLDRARNAIKGLMQLTPERATVQQADGSWSDVDAKSVTLGSVVRIKPGERIGLDGQIVQGRSSINQAPITGESLPVDKAEGDAVFAGTINESGSFDYRVTAAANDSTLARIIHAVEEAQGAKAPTQRFVDQFSRIYTPTVFGLAVLVAVLPPLLITGAGWHEWIYKALVLLVIACPCALVISTPVTIVSGLAAAARRGILIKGGVYLEDGRKLSWLALDKTGTITHGKPMQTDFAVIATDVSAEDSQRWAMSLAARSDHPVSKAIAKANIGTAPEQVEAFEALLGRGVRGVINGRNYFLGNHHMVEELGRCSLELEARLDVLERQGKSVVLLVDDSHVLALFAVADTVKESSRAAIAELHALGIKTMMLTGDNPHTAEAIAAQVGIDEARGNQLPQDKLQAIEALARKGAVVGMVGDGINDAPALARANIGFAMGAMGTDTAIETADVALMDDDLRKIPGFVRLSRATHSILMQNIALALGIKLVFLVLTLTGAGTMWMAVFADVGASLLVIGNGLRLMRHKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVP3</accession>
    <name>A0A2S9GVP3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3539</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000019">
        <property type="protein sequence ID" value="PRC91784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91784">
        <property type="protein sequence ID" value="PRC91784"/>
        <property type="gene ID" value="S2091_3539"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="32" mass="3522" checksum="88B513DD071753C5" modified="2018-07-18" version="1">MTVYGHFAGKHFKNINDCDLGGLLASHDMTDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GW36</accession>
    <name>A0A2S9GW36_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">MerR HTH family regulatory protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3275</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000017">
        <property type="protein sequence ID" value="PRC91933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91933">
        <property type="protein sequence ID" value="PRC91933"/>
        <property type="gene ID" value="S2091_3275"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="107" mass="12068" checksum="55F5C89C643FB7B4" modified="2018-07-18" version="1">MSTNISECIWLSDHDVCSANHLIAVSGLSAEEFDELVQIGIITPINDSKYYRLSYIVTANTARRLRDDFELDLHGMGLAMTLMLRIENLQAELNNARARIPASIRPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GW75</accession>
    <name>A0A2S9GW75_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Serine hydroxymethyltransferase</fullName>
            <shortName evidence="7">SHMT</shortName>
            <shortName evidence="7">Serine methylase</shortName>
            <ecNumber evidence="7">2.1.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">glyA</name>
        <name evidence="10" type="ORF">S2091_3315</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + glycine + H2O = (6S)-5,6,7,8-tetrahydrofolate + L-serine</text>
            <dbReference type="Rhea" id="RHEA:15481"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="EC" id="2.1.2.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 7 8">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Amino-acid biosynthesis; glycine biosynthesis; glycine from L-serine: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="7">One-carbon metabolism; tetrahydrofolate interconversion.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the SHMT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.1" evidence="7"/>
    <dbReference type="EMBL" id="PUGF01000017">
        <property type="protein sequence ID" value="PRC91973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91973">
        <property type="protein sequence ID" value="PRC91973"/>
        <property type="gene ID" value="S2091_3315"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00193"/>
    <dbReference type="UniPathway" id="UPA00288">
        <property type="reaction ID" value="UER01023"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004372">
        <property type="term" value="F:glycine hydroxymethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019264">
        <property type="term" value="P:glycine biosynthetic process from serine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035999">
        <property type="term" value="P:tetrahydrofolate interconversion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00378">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00051">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001085">
        <property type="entry name" value="Ser_HO-MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019798">
        <property type="entry name" value="Ser_HO-MeTrfase_PLP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039429">
        <property type="entry name" value="SHMT-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11680">
        <property type="entry name" value="PTHR11680"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00464">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000412">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00096">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4 7" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="6 7 8" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SHMT" evidence="9">
        <location>
            <begin position="11"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="128"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="38"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="58"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="60"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="67"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="68"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="124"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="179"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="207"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="232"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="239"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="365"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="7 8">
        <location>
            <position position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000412-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC91973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="423" mass="45259" checksum="2113719AE179E7FA" modified="2018-07-18" version="1">MSNKAFFNNSLAQTDSAVMTAINGEMHRQRDQIEMIASENIVSKAVLEAQGSVLTNKYAEGYPGKRYYGGCDQVDVVETLAIERAKQLFDAAYVNVQPHSGAQANGAVMLALVKPGETVLGMSLSAGGHLTHGAKPALSGKWFNAIQYGVRRVDCLIDYEEVERLALEHKPKLIIAGFSAYPREVDWARFRAIADSVGAYLMVDMAHIAGLVATGLHASPVPHAHVTTSTTHKTLRGPRGGIIMTNDEEIAKKINSAVFPGLQGGPLMHVIAAKAVAFGEALQPEFTSYIKQVVANARALGEVLVAGGVDLVTGGTDNHLLLVDLRPMGLKGNTTEHALERAGFTCNKNGIPFDDEKPTVTSGVRLGTAAGTTRGFGEQEFRQIGALILDVLNGLRTNPEGNSAIENRVRAEVAAICKEFPIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GW78</accession>
    <name>A0A2S9GW78_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Helix-turn-helix domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3472</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000018">
        <property type="protein sequence ID" value="PRC91916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91916">
        <property type="protein sequence ID" value="PRC91916"/>
        <property type="gene ID" value="S2091_3472"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025194">
        <property type="entry name" value="DUF4115"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13464">
        <property type="entry name" value="DUF4115"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="134"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="domain" description="HTH cro/C1-type" evidence="2">
        <location>
            <begin position="30"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00530"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="328" mass="35146" checksum="10171A5A0FD2F678" modified="2018-07-18" version="1">MSEGVKLAIVSESGASQSTHASNAMSVGERLAFARTQQGLSIEQIAGQLKWSTRQIVEIEAGNYAVLPDLSTVRGFVRTYAKILKLDAAPLLEELSLEFAKLPVKAVDRPLLDTPFPTGRMPWLGRQNNRSQRVFGGLFLAFLVLLAVFVYRAELFHLFRSILPVSVESKAEHADVLTVQPDTHIAMPATLEANSPSVGISPSGVSRPVAEASVAPVSASVPTQVPASVSANESLPVTPVQKTETKNINPDDSLVLSFKQDSWVQIKHSDGSAVSSHLYKAGTEEVVNVSQPLNLIIGNGPGVEAKLRGQNLVLQKQNGSNVVNLSVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GW96</accession>
    <name>A0A2S9GW96_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3347</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000017">
        <property type="protein sequence ID" value="PRC92005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92005">
        <property type="protein sequence ID" value="PRC92005"/>
        <property type="gene ID" value="S2091_3347"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="83"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="129"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="155"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="188"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="217"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="256"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="297"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="324" mass="36051" checksum="28B9D3D89121DF6D" modified="2018-07-18" version="1">MKTMKWLIRREFWEHKGSFFWAPLIVAAIMSVFILGIVSLGVSADNIRGTYGEVNDTQVSMSTLAAQVSDAQKAQLANTMANAYMFVTAPLFIVLSFIVFFYCLSSLYEERRDRSILFWKSLPVSDGMTVLSKLMMAAGVAPLITIAVATVTSLLVLLMFCAALAFKGINVFGLLLSTPALYAAPFQLLGMLPIYLLWALPTIGWLLMVSAWARSKVFLWAVGVPCLSMALLVWAERLFNFQWNIVWYAKNIVARLLLGVIPGGWVSLVDLGNAQIITQHRSGVEMSGIFTQSWATLAYPELWIGVAAGVAMIYVAIRLRRWRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWG4</accession>
    <name>A0A2S9GWG4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3166</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000016">
        <property type="protein sequence ID" value="PRC92031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92031">
        <property type="protein sequence ID" value="PRC92031"/>
        <property type="gene ID" value="S2091_3166"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015553607" evidence="1">
        <location>
            <begin position="30"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="145" mass="16195" checksum="C1BAFE0B3A04E918" modified="2018-07-18" version="1">MKKISINPIALFPLTALLFFVLPSQQAYAQTKTAQDLAPLNLDTAQIAKEISHDEHDEHVEKHTETLSAAPNKFTESFSKAAVVRRGPPTVEEIHEQGTTDRVDKVIPVWGDEYCVYSPSQGRTDGIDPIQTGMPTQFRSCPHYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWM6</accession>
    <name>A0A2S9GWM6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3260</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000016">
        <property type="protein sequence ID" value="PRC92125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92125">
        <property type="protein sequence ID" value="PRC92125"/>
        <property type="gene ID" value="S2091_3260"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="191" mass="22397" checksum="2972A7DC51FFE1F8" modified="2018-07-18" version="1">MPCPKPEIYCNLFGCMTQAEWLQSIGYGIATVVAGFSIWSYFYSQKKQRELDMVKFSIELHRRLFDDEDLKEILNLIDGTILEQASLEEFKMGSKKRKFITFFEEMSLLVRAKFISEDFALYMFGYYAMQAKDNKHFMNDDMSDERVDFGIFFDFAESYRAKESTLNPSKILITHPSLITKLKNRLNPFGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWU1</accession>
    <name>A0A2S9GWU1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3261</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000016">
        <property type="protein sequence ID" value="PRC92126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92126">
        <property type="protein sequence ID" value="PRC92126"/>
        <property type="gene ID" value="S2091_3261"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009659">
        <property type="entry name" value="DUF1249"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06853">
        <property type="entry name" value="DUF1249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="73" mass="8350" checksum="EB85878F1137A9B0" modified="2018-07-18" version="1">MIADPDMVIAVYPEAEMVEVMTYQDCFGFRKVYSDDMSLVSPSTKKELNSFLSQWLTNIKNQGHQIGKNESEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWU9</accession>
    <name>A0A2S9GWU9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Membrane-bound lysozyme-inhibitor of c-type lysozyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3094</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92178">
        <property type="protein sequence ID" value="PRC92178"/>
        <property type="gene ID" value="S2091_3094"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036328">
        <property type="entry name" value="MliC_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141488">
        <property type="entry name" value="SSF141488"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015671141" evidence="1">
        <location>
            <begin position="22"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="141" mass="15752" checksum="8A4D922DA081C744" modified="2018-07-18" version="1">MKFCTICAAITLSITSQFVFAQSTTPTPVKKTATKKAVPAQEVSNDEDDMTPDIKESTTYEYKCELKDSLTIYTNSDDNDHVALRWKNKLYRLKRVVTTTGANRFENKKAGLVWIGIPTKGMLLDSRHGQQLANDCKTAGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWV0</accession>
    <name>A0A2S9GWV0_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">Dihydrolipoyl dehydrogenase</fullName>
            <ecNumber evidence="3 7">1.8.1.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">S2091_3106</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>(R)-N(6)-dihydrolipoyl-L-lysyl-[protein] + NAD(+) = (R)-N(6)-lipoyl-L-lysyl-[protein] + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:15045"/>
            <dbReference type="Rhea" id="RHEA-COMP:10474"/>
            <dbReference type="Rhea" id="RHEA-COMP:10475"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:83100"/>
            <dbReference type="EC" id="1.8.1.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5 7">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="5 7">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="7">The active site is a redox-active disulfide bond.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.8.1.4" evidence="3 7"/>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92190">
        <property type="protein sequence ID" value="PRC92190"/>
        <property type="gene ID" value="S2091_3106"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004148">
        <property type="term" value="F:dihydrolipoyl dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016156">
        <property type="entry name" value="FAD/NAD-linked_Rdtase_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006258">
        <property type="entry name" value="Lipoamide_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001100">
        <property type="entry name" value="Pyr_nuc-diS_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004099">
        <property type="entry name" value="Pyr_nucl-diS_OxRdtase_dimer"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02852">
        <property type="entry name" value="Pyr_redox_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000350">
        <property type="entry name" value="Mercury_reductase_MerA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55424">
        <property type="entry name" value="SSF55424"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01350">
        <property type="entry name" value="lipoamide_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0274">FAD</keyword>
    <keyword evidence="7" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5 7" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyr_redox_2" evidence="9">
        <location>
            <begin position="5"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="domain" description="Pyr_redox_dim" evidence="8">
        <location>
            <begin position="356"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="454"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="58"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="122"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="153"/>
            <end position="155"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="190"/>
            <end position="197"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="213"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="281"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="322"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="328"/>
            <end position="331"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="6">
        <location>
            <begin position="49"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012608"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC92190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="475" mass="50173" checksum="989B8E71536FBBCA" modified="2018-07-18" version="1">MSIQFDVVVIGGGPGGYIAAIRAAQLGFKVACIDEWKNAKGGAAPGGTCTNVGCIPSKALLQSSEHFEHAGHSFADHGIEVQGLKLDLVQMLKRKETIIKQNNDGILYLFKKNKVNFFHGRGAFVAAVDGGYEISVTGVNSENITGKHIIVATGSNARALPGTPFDEELILSNTGALDINAVPKKLGVIGAGVIGLEMGSVWRRLGSEVTVLEALPAFLGAVDDQIAKEALKLFTKQGLAINLGVKIGKITSGKKNVTVEYTDAKGAEQKAEFDKLIISIGRTPNTIGLNAEAIGLQLDERGFVAVDGDCKTNLANVWAVGDVVRGPMLAHKAEEEGVAVAERIAGQHGHVNFNTVPWVIYTSPEIAWVGRTEQQLKADGVAYKAGTFPFMANGRARALGDTSGMVKFLADAVTDEILGVHIIGPMASELISEAVVAMEFKASAEDIARICHAHPSLSEATKEAALAVDKRALNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GX13</accession>
    <name>A0A2S9GX13_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2918</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92259">
        <property type="protein sequence ID" value="PRC92259"/>
        <property type="gene ID" value="S2091_2918"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="78"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="161"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="192" mass="22197" checksum="CBCE03DFBB011911" modified="2018-07-18" version="1">MKLMKNAPSILNVLYSTLTAKYWKKRPESHEIIVLALLLVFMSYKMMHTGWVPLLDWATLTIHEAGHPIIGMLLGNRMMVYGGSLFQLIFPLVFVWHFARQDQALGYCFAISWEASSLHALGRYVADARAQELPLVGNGDRIHDWNEILGRWNLLDYDRLLGGWLYVLCWMLMACCFFMLWNLWRALGDAGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GX26</accession>
    <name>A0A2S9GX26_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Short chain fatty acids transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2936</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92277">
        <property type="protein sequence ID" value="PRC92277"/>
        <property type="gene ID" value="S2091_2936"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006160">
        <property type="entry name" value="SCFA_transpt_AtoE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41983">
        <property type="entry name" value="PTHR41983"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02667">
        <property type="entry name" value="SCFA_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="27"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="103"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="145"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="194"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="254"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="277"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="318"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="350"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="436"/>
            <end position="459"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="470" mass="50608" checksum="F76BCD8D3DCEBEA4" modified="2018-07-18" version="1">MATIFSNALEHTAQAVTSWAEKWFPDAYIFAALAVVVVAAGAWFMGAPLTQIGIAFGDGYWSLIPFTMQMAMVAISGYVLAVSPPAAALIARLAKLPRSGRSAVAFVAMVSIIASFISWAISLIFAGLLVRALARRTDLRMDYRAAGAAAYLGLGATWALGLSSSAAQLQTNPASLPPTLLAITGVLPFSQTIFLPQSMLLALIIMLVSICIAYFSAPRDANASTADDLAVNLDDTPETTDIDRPGDWLERSPLLTLLIVALGALWIWHEFSSKNPLIAITNLNTYNFVLLLFGMLCNWRPQRFLRAVTQSVPSTAGVLIQFPLYGGIAFILTKAGAADGHTLSHYLAQFFVTISTHSSFPGVIGIYSAILGFFVPSGGGKWIIEAPYVMQAAIDLKVHLGWAVTVYNAAEALPNLINPFWMLPLLGILRLKARDIVGYTFVQFIVHVPLVIFLLWALAGTLSYLPPAMP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GX71</accession>
    <name>A0A2S9GX71_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NUDIX domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2972</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92313">
        <property type="protein sequence ID" value="PRC92313"/>
        <property type="gene ID" value="S2091_2972"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="1">
        <location>
            <begin position="10"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="229" mass="25849" checksum="D127F74941AE6515" modified="2018-07-18" version="1">MNTILQIEKPLFTVDSVLFTVHDGVLKVLMAKRAESPFEGYWGLPGGFIDINVDENTDMTARRKLLNKTGLVPSYLEQLQVISGPKRDPRGYSVTLAYYALVAHQNVESKIASVESACWLSVSELPKLLIAFDHRHIIDIAQQRLQQKTLYSMIPVFCLPEKFSIGQLIKVIEAIIEKPIQRKSLMRRIEASEMFEISNEKISSGGRLAQLYSLKPGADIVNFERNLSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXB0</accession>
    <name>A0A2S9GXB0_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cell division protein FtsB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">ftsB</name>
        <name evidence="4" type="ORF">S2091_3008</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Part of a complex composed of FtsB, FtsL and FtsQ.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell inner membrane</location>
            <topology evidence="3">Single-pass type II membrane protein</topology>
        </subcellularLocation>
        <text evidence="3">Localizes to the division septum.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the FtsB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92349">
        <property type="protein sequence ID" value="PRC92349"/>
        <property type="gene ID" value="S2091_3008"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032153">
        <property type="term" value="C:cell division site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043093">
        <property type="term" value="P:FtsZ-dependent cytokinesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00599">
        <property type="entry name" value="FtsB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023081">
        <property type="entry name" value="Cell_div_FtsB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007060">
        <property type="entry name" value="FtsL/DivIC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37485">
        <property type="entry name" value="PTHR37485"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04977">
        <property type="entry name" value="DivIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="1 3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2 3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="topological domain" description="Cytoplasmic" evidence="3">
        <location>
            <begin position="1"/>
            <end position="3"/>
        </location>
    </feature>
    <feature type="topological domain" description="Periplasmic" evidence="3">
        <location>
            <begin position="22"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="36"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00599"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC92349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="95" mass="10909" checksum="EE3A0788F8F49FA9" modified="2018-07-18" version="1">MRLIAIVLAALLLLIQYPLWLGKGGWLRVWDMEHQVDVAHIKIQELKTRNAKLESEVNDLKEGTDAVEERARFELGMLKKGEVFIQILDAPKKSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXB3</accession>
    <name>A0A2S9GXB3_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6249 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3021</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92362">
        <property type="protein sequence ID" value="PRC92362"/>
        <property type="gene ID" value="S2091_3021"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046216">
        <property type="entry name" value="DUF6249"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19762">
        <property type="entry name" value="DUF6249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="14"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="90"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="114"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6249" evidence="2">
        <location>
            <begin position="26"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF19762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="141" mass="15489" checksum="8BA52919BE5D2632" modified="2018-07-18" version="1">MYSNDSISIISSQIVPIVAIIMSIGTPVAIVMAILHYKAKRNQMLHETIQQLAQKGLPIPRELLNGVANNSDSNKSDFDNPGKKSALSKGIILIAIGIGMSIMFYVLPDRINNAWGVGMIPLLMGIGYLLIWKLENRDQNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXC3</accession>
    <name>A0A2S9GXC3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">MoaD: molybdopterin converting factor, subunit 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3031</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92372">
        <property type="protein sequence ID" value="PRC92372"/>
        <property type="gene ID" value="S2091_3031"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016155">
        <property type="entry name" value="Mopterin_synth/thiamin_S_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003749">
        <property type="entry name" value="ThiS/MoaD-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02597">
        <property type="entry name" value="ThiS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54285">
        <property type="entry name" value="SSF54285"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="89" mass="9711" checksum="EAF5F2E6C50309B4" modified="2018-07-18" version="1">MTAGFTIQLRFFASVREQLGCSEQTVTLPPEVVTVGQVRQWLIGRGGVWAVTLAQGRNLRAAYQQEMCDESVEIADGHEVAFFPPVTGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXH2</accession>
    <name>A0A2S9GXH2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2783</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92408">
        <property type="protein sequence ID" value="PRC92408"/>
        <property type="gene ID" value="S2091_2783"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="141" mass="15391" checksum="1284F96998F00CA6" modified="2018-07-18" version="1">MKTFTIEQARAATSSGGVLSVNLKPIGSMFALEFVTHNGPAMLIAAVSKQVRRFSNPIKAFEIVRELGLEGGHFSVAEWHPEEKALDRPTRPDKAAALKAAHQAAGLKHLLDERVNLANAPDAIWHEAEDVFAELEIRNAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXK3</accession>
    <name>A0A2S9GXK3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">GGDEF: diguanylate cyclase (GGDEF) domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_2832</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92457">
        <property type="protein sequence ID" value="PRC92457"/>
        <property type="gene ID" value="S2091_2832"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01948">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001633">
        <property type="entry name" value="EAL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035919">
        <property type="entry name" value="EAL_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00563">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00052">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141868">
        <property type="entry name" value="SSF141868"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50883">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GGDEF" evidence="3">
        <location>
            <begin position="181"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="domain" description="EAL" evidence="2">
        <location>
            <begin position="323"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC92457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="586" mass="64942" checksum="3B07F4A56039F90C" modified="2018-07-18" version="1">MSIDDNGLTSHREHSDQSNVTSLHKGASPPVDEQNITSRESAVVDDEIAVRDREKLASSREDAAHLRENAIGLREDAAHMRERTALAREREARVRESAVTLREQEICGPGPSSDHSIVLRQANEHLVIAAIESQKLVEIVQTAKMELDHLAHHDVLTDLPNRILLLDRLTQAIELARRQGKQLAVMFLDLDHFKYINDSLGHTVGDLLLQSIAHLLVACVRNSDTVSRQGGDEFVLLLPSIEHVNDAAHCAQKIITAFTLPHSIDQHNLHISVSIGVSIYPDDGLDAETLIKSADTAMYHAKEGGRENFKFFKQEMNDRAVQRQSVEASLRLALERQEFVLYYQPKVNLRSGAIVGCEALIRWQHPERGLLSPEQFVSIAEDCGLILPIGRWVLREACLQALAWRQAGLRPIVVAVNTSALELRAMDFLENIRATLVETSMEPRYLELELTESVLMQDAESSNSALLALHDLGAKLALDDFGTGYSSLSYLRRFPIDTLKIDQSFVNHITSNKDDATIVCSVVSLGKSLNKRVIAEGVETQEQYEFLLAQECDEGQGFYLSRPVVAAALAALLQSGVSLPVYDGAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXM4</accession>
    <name>A0A2S9GXM4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Helix-turn-helix domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2847</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92472">
        <property type="protein sequence ID" value="PRC92472"/>
        <property type="gene ID" value="S2091_2847"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018062">
        <property type="entry name" value="HTH_AraC-typ_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013656">
        <property type="entry name" value="PAS_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020449">
        <property type="entry name" value="Tscrpt_reg_HTH_AraC-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08448">
        <property type="entry name" value="PAS_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00032">
        <property type="entry name" value="HTHARAC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00041">
        <property type="entry name" value="HTH_ARAC_FAMILY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="2">
        <location>
            <begin position="161"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="264" mass="29635" checksum="B2A31D22DCF84CDC" modified="2018-07-18" version="1">MINHANAAKNSPSSTMLQSLLGCEPSIRIADLGFVESLFDALLDVVFFVKDKQGRYLIVNNTLVRRCGLRSKEEMIGKMVDSVFAKPLAESFNAQDQMVITTGIALEKHLELHLYQTRERGWCLTHKIPLRDTSGAVVGLVGISQDLGLPDKTHPEYRQIASITDTIRENYHQDISISKLAENAKMPLARVERLFQKVFHFSPRQLLLQSRLNAALAIIESGDQRSIADIAYACGYTDHSAFSRQFKALIGMPPVEYRAHFFAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXQ0</accession>
    <name>A0A2S9GXQ0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Acetyltransferase (GNAT) family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2811</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92436">
        <property type="protein sequence ID" value="PRC92436"/>
        <property type="gene ID" value="S2091_2811"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13673">
        <property type="entry name" value="Acetyltransf_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="2">
        <location>
            <begin position="1"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="169"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="191" mass="21636" checksum="5BC9D70640D33D5F" modified="2018-07-18" version="1">MIRAAISADITALLAIENSSFQGDRLTQRSFRHLLMHGNSITLVDEHNGQLRGYVTLLFRRNNSRSRLYSIATHPHFLGQGVAAMLLIAAEQAALSSNCVTMRLEIRKDNQASLQLFQHRGYRIFDEYSGYYQDGMSAFRLEKSLTHLLRPEPVRAPYYRQTLGFSLSDDGDESIQTQSRSKSHTRATTLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXT0</accession>
    <name>A0A2S9GXT0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="12">AhpF: alkyl hydroperoxide reductase subunit F</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">S2091_2841</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="8">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92466">
        <property type="protein sequence ID" value="PRC92466"/>
        <property type="gene ID" value="S2091_2841"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008785">
        <property type="term" value="F:alkyl hydroperoxide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000302">
        <property type="term" value="P:response to reactive oxygen species"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03026">
        <property type="entry name" value="AhpF_NTD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02974">
        <property type="entry name" value="AhpF_NTD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044141">
        <property type="entry name" value="AhpF_NTD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044142">
        <property type="entry name" value="AhpF_NTD_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012081">
        <property type="entry name" value="Alkyl_hydroperoxide_Rdtase_suF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008255">
        <property type="entry name" value="Pyr_nucl-diS_OxRdtase_2_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012336">
        <property type="entry name" value="Thioredoxin-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13192">
        <property type="entry name" value="Thioredoxin_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000238">
        <property type="entry name" value="AhpF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03140">
        <property type="entry name" value="AhpF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00573">
        <property type="entry name" value="PYRIDINE_REDOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5 8" id="KW-0520">NAD</keyword>
    <keyword evidence="8" id="KW-0521">NADP</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7 9" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin-like_fold" evidence="11">
        <location>
            <begin position="128"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="domain" description="Pyr_redox_2" evidence="10">
        <location>
            <begin position="216"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="217"/>
            <end position="232"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="481"/>
            <end position="491"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="9">
        <location>
            <begin position="348"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000238-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000238-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF13192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PRC92466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="521" mass="56049" checksum="BC4AD5AC0B1082F5" modified="2018-07-18" version="1">MLDSTLKTQLKAYLEKVTQPIELVATLDNSDVSRDMRALLDDIVSLSNQITLTISTDATLRAPSFSINRLHKEQGEVGIRFAGIPMGHEFTSLVLALLQTGGHPPKVDTAVIEQIVQLDGDYQFETYISLTCQNCPEVVQSLNLMAVLNPRIRSVVIDGALFQEEVEQRQVMAVPTIFLNGKVFDQGRLSIEEILAKLDSGLEKRTAEKLDASASYDVLVVGGGPAGAAAAIYSARKGIRTGVVGERFGGQVLDTMSIENFISVTETEGPKFAAALEQHVKTYDVDIINLQRAEKLIPASAANPLTEIKLASGATLKAKTVIIATGARWREINVPGEREYRNHGVAYCPHCDGPLFKGKRVAVIGGGNSGVEAAIDLAGLVSHVTLLEFGAELRADEVLQRKLRSLTNVTVHTSAQTTEVKGDGKKVNGIDFKDLTSGELKHVELEGVFVQIGLVPNTEWLKGTLELSRHGEIIVDARGQTSLPGVFAAGDVTTVPFKQIVIAVGEGAKAALSAFDHLIRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GY79</accession>
    <name>A0A2S9GY79_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2740</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92685">
        <property type="protein sequence ID" value="PRC92685"/>
        <property type="gene ID" value="S2091_2740"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="158" mass="18192" checksum="6433B4DE34CF5847" modified="2018-07-18" version="1">MIFLYPFLACFSLLITIFSMLVLNWIVVLFVDAKGNLPPWLSYFQTFDAPLPTGYLTGVMWLMRNPTYGFDYFVFGIPWDPDEWTVQLFRTNATRDFFIATSKNGGFNFYYLGTLGMYKFGWKAWNCFDSATGKFSGTFGDGSHVPICITFNPFKTKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYB4</accession>
    <name>A0A2S9GYB4_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="4">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">S2091_2445</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="4"/>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92715">
        <property type="protein sequence ID" value="PRC92715"/>
        <property type="gene ID" value="S2091_2445"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000687">
        <property type="entry name" value="RIO_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018935">
        <property type="entry name" value="RIO_kinase_CS"/>
    </dbReference>
    <dbReference type="SMART" id="SM00090">
        <property type="entry name" value="RIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01245">
        <property type="entry name" value="RIO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 12" id="KW-0418">Kinase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 12" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="17"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PRC92715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="283" mass="31600" checksum="54AE2B1769595ABF" modified="2018-07-18" version="1">MKTPKRILPLVEEGLIDEVVRQLMSGKEATVFVVRCGDEIRCAKVYKEANQRSFHQAVAYQEGRRVKNSRQARAMEKGSKYGRKMAEEVWQNAEVDALYRLAAAGVRVPTPYICFEGVLLMDLVTDANGNVAPRLNDVEFDHDKALKFHTMLLREVVLMLCAGVIHGDLSEYNILVDEQGPVIIDLPQAIDAAGSSVASSMLERDVTNLANFFGTFAPELIGSQYGKEIWNLYEAGLLTPDFALTGKVPAPTEPVDVESVINEIESARLEEEDRVRRQLEMQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYC4</accession>
    <name>A0A2S9GYC4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2457</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92727">
        <property type="protein sequence ID" value="PRC92727"/>
        <property type="gene ID" value="S2091_2457"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="150" mass="16796" checksum="28BF4C670420DB19" modified="2018-07-18" version="1">MGYLKLRLEDEGDGSGELFVQFEQNGFSGHGSAWFNLKLLGEKAMEFKKYPLQNDRSAYISGGFWEESYPAKLKEELLHISAYPINQRGGVAIYVKVANRPFGSERESEPLSIAAAEIVTSYPRLEVFSNDLKNLLDGILDEVVLSTGRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYK0</accession>
    <name>A0A2S9GYK0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2521</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92791">
        <property type="protein sequence ID" value="PRC92791"/>
        <property type="gene ID" value="S2091_2521"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="189"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="279" mass="30710" checksum="5EC813EDF12A4373" modified="2018-07-18" version="1">MISIIAHKTNQDKIPQDRTVLWLRIGALLVGIIASVLFLISFLNYSNYRKTFLELNLNRYLVMAKDVRQTIVLGLNVGLKPAENTHLPPIMKDMIQRQSGIRYIGIVDESGEAITQGQVAAKTVAEWKTWINKTAAEDSWHTSDADTFQIGVPFLNNFNVKVGAVVIGYDKHVIEGAINDMGRTLLLDVLATLSFFTVITFAGVYLLTRKFVGKIAAIGQAIDSTLIAIEPTEVGDDMLDSGVAKDINDFTASSQQLVSTIAKLERAILPSHHKNVEAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYK4</accession>
    <name>A0A2S9GYK4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2510</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92780">
        <property type="protein sequence ID" value="PRC92780"/>
        <property type="gene ID" value="S2091_2510"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="40" mass="4797" checksum="010ABF979C558048" modified="2018-07-18" version="1">MSTSPFSLWQGLLKTRFSKRPWMIDRSINPARSQFVLLHY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYL6</accession>
    <name>A0A2S9GYL6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Outer membrane efflux protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2528</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92798">
        <property type="protein sequence ID" value="PRC92798"/>
        <property type="gene ID" value="S2091_2528"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015562">
        <property type="term" value="F:efflux transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003423">
        <property type="entry name" value="OMP_efflux"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02321">
        <property type="entry name" value="OEP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="21"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="539" mass="58350" checksum="450CD6688F71A3A1" modified="2018-07-18" version="1">MHKIKTISVNYGDQSISNNGLVRLLMMAFFVFLFPRLVCAGELRLDEAIRLALAHNPDVKVQERQVDVAVGQRMEATGQFDLTLVSGANYSKAITPFIDNLNTLNQTLAISTGYQIGLNKELRDGISLTTAMQAAAIQSSGYGVSPQLQQNAMALNITLNVPLLKGGGSDEVTEAEDVGKINVVASQYGLRNQVVQTVYNTLQSYWNYLASLELLKVAQSSEERSKNLLDSNQKLVDAAEKPRADLVLLKADYADKIVARQMAALTATNAKLALGRVLGIDAVAIRAMADPIDGFPADMNAVSLVPRLEAMSSEALLIRPDVKVLALQLEAAQRHLLAAQKKLRPQLNLSLGVNYTNVSAGGSPYGFIADPSRPVSTPSVNVQLNYQFPIDNTQAKGSFLENSALVDQLSVKQRDLEIDVTTSVDNALQSAIQTAAQLKISQESLALYEQAVSQEIIKQKNGISTLIDVINVEARFVSARVNYIQQQQAYANALATLRLVTGTFLPNTAPFESGGNSFSLDIGSLVGLGPLNHYRSFPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYU5</accession>
    <name>A0A2S9GYU5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2287</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92870">
        <property type="protein sequence ID" value="PRC92870"/>
        <property type="gene ID" value="S2091_2287"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004844">
        <property type="term" value="F:uracil DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002043">
        <property type="entry name" value="UDG_fam1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036895">
        <property type="entry name" value="Uracil-DNA_glycosylase-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11264">
        <property type="entry name" value="PTHR11264"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52141">
        <property type="entry name" value="SSF52141"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="263" mass="28813" checksum="9278AC4BA8E48A22" modified="2018-07-18" version="1">MTAAKKVALPEFIETALAAAHPSWHAHLRSGLNAMSAEQPNYFSTLAQHDFFPTENRLFAAFTQPITSVRFVLLGEGPYPRAASATGVCFMDGAVQSLWQPGAGLSKPVNRATSLRNFIKMVLVAEGVLNIQNTTASALTSVAELACAPNSGWIQTGAELQANLMQQGFLLLNASLVFRTEVAPVQDAKAWLPFLRTILQALSMQNELEIKLILWGKIAEKIRELPEADKFLALASEHPYNLSFIANPVMQNLFKSLHLFKAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZ09</accession>
    <name>A0A2S9GZ09_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Probable chemoreceptor glutamine deamidase CheD</fullName>
            <ecNumber evidence="3">3.5.1.44</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">cheD</name>
        <name evidence="4" type="ORF">S2091_2389</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>H2O + L-glutaminyl-[protein] = L-glutamyl-[protein] + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:16441"/>
            <dbReference type="Rhea" id="RHEA-COMP:10207"/>
            <dbReference type="Rhea" id="RHEA-COMP:10208"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29973"/>
            <dbReference type="ChEBI" id="CHEBI:30011"/>
            <dbReference type="EC" id="3.5.1.44"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CheD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.44" evidence="3"/>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92972">
        <property type="protein sequence ID" value="PRC92972"/>
        <property type="gene ID" value="S2091_2389"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050568">
        <property type="term" value="F:protein-glutamine glutaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd16352">
        <property type="entry name" value="CheD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01440">
        <property type="entry name" value="CheD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038592">
        <property type="entry name" value="CheD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005659">
        <property type="entry name" value="Chemorcpt_Glu_NH3ase_CheD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011324">
        <property type="entry name" value="Cytotoxic_necrot_fac-like_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35147">
        <property type="entry name" value="PTHR35147"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03975">
        <property type="entry name" value="CheD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64438">
        <property type="entry name" value="SSF64438"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0145">Chemotaxis</keyword>
    <keyword evidence="2 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01440"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC92972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="203" mass="22577" checksum="293923B96800F70D" modified="2018-07-18" version="1">MSVMSIEHLASNFYFDRTFDCEAAKILPGEYYFSGKDMVIVTVLGSCVSACIRDRVTGVGGMNHFMLPDGGGDADSPVSASMRYGTYAMEILINELLKAGARRENFEAKVFGGGNVLRGFTSINVGERNAKFVREYLKTENIKITAEDLIDIHPRKVYFFPRTGKVLVKKLKVVHNDTLKQRELEYAGKLKKDSLGGGEIDLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZ31</accession>
    <name>A0A2S9GZ31_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 13">Dihydrolipoyl dehydrogenase</fullName>
            <ecNumber evidence="3 13">1.8.1.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">S2091_2303</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>(R)-N(6)-dihydrolipoyl-L-lysyl-[protein] + NAD(+) = (R)-N(6)-lipoyl-L-lysyl-[protein] + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:15045"/>
            <dbReference type="Rhea" id="RHEA-COMP:10474"/>
            <dbReference type="Rhea" id="RHEA-COMP:10475"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:83100"/>
            <dbReference type="EC" id="1.8.1.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11 13">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="11 13">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="13">The active site is a redox-active disulfide bond.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.8.1.4" evidence="3 13"/>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92886">
        <property type="protein sequence ID" value="PRC92886"/>
        <property type="gene ID" value="S2091_2303"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004148">
        <property type="term" value="F:dihydrolipoyl dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016156">
        <property type="entry name" value="FAD/NAD-linked_Rdtase_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006258">
        <property type="entry name" value="Lipoamide_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001100">
        <property type="entry name" value="Pyr_nuc-diS_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004099">
        <property type="entry name" value="Pyr_nucl-diS_OxRdtase_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012999">
        <property type="entry name" value="Pyr_OxRdtase_I_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02852">
        <property type="entry name" value="Pyr_redox_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000350">
        <property type="entry name" value="Mercury_reductase_MerA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55424">
        <property type="entry name" value="SSF55424"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01350">
        <property type="entry name" value="lipoamide_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00076">
        <property type="entry name" value="PYRIDINE_REDOX_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5 11 13" id="KW-0274">FAD</keyword>
    <keyword evidence="4 13" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7 11 13" id="KW-0520">NAD</keyword>
    <keyword evidence="11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9 13" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyr_redox_2" evidence="15">
        <location>
            <begin position="8"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="domain" description="Pyr_redox_dim" evidence="14">
        <location>
            <begin position="353"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="10">
        <location>
            <position position="451"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="52"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="154"/>
            <end position="156"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="190"/>
            <end position="197"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="213"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="279"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="319"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="325"/>
            <end position="328"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="12">
        <location>
            <begin position="43"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012608"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU003692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="PRC92886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="472" mass="49443" checksum="F041FDA228B2928C" modified="2018-07-18" version="1">MHTQTTTLLIIGGGPGGYVAAIRAAQLGIATTLVEAAELGGTCLNIGCIPSKAMIHAAEEFAKACEYAGTSPLGIHVQAPRIEVSQTVLWKNGIVGKLTGGVGALLKKHNVTVIKGWAKIVDGKTVDVTQKEGDAKGDATTTLRISCRHLLLATGSLPVALPTMPFGGRVISSTEALSPTSLPKKLVVVGAGYIGLELGTAYRKMGVEVSVVESLDRVLPAYDTELTRPVGASLKRLGINLHLGCTVQGLNAAGDAVRIRNGEGIESELPADQVLVAVGRRPNTAGWNMESLMLDMNGRSVSINDQCRTSMLDVWAIGDLTGEPMLAHRAMAQGEMVAEIIAGKRRHFQPAAMPAVCFTDPEVVVVGKTPNDAQQAGLDCINATFPFAANGRAMTIESNDGFVRVVARRDNHLIVGWQAVGRGVSELSAAFSQSIEMGAALEDIAGTIHAHPTLGEAVQEAALRAMGHALHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZ88</accession>
    <name>A0A2S9GZ88_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">MutS domain V</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_2127</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93041">
        <property type="protein sequence ID" value="PRC93041"/>
        <property type="gene ID" value="S2091_2127"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030983">
        <property type="term" value="F:mismatched DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000432">
        <property type="entry name" value="DNA_mismatch_repair_MutS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045076">
        <property type="entry name" value="MutS_family"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361">
        <property type="entry name" value="PTHR11361"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00488">
        <property type="entry name" value="MutS_V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00534">
        <property type="entry name" value="MUTSac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="165"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="domain" description="DNA_MISMATCH_REPAIR_2" evidence="4">
        <location>
            <begin position="334"/>
            <end position="513"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC93041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="533" mass="59998" checksum="D47CFA377D0FE652" modified="2018-07-18" version="1">MFSFIFNFAASKSAKISRSFFPEKEPAAFPEYTFEQIAAFHQITLHNARQMDDATWRDLQVDAYLRKISASVSIFARQTLYKLLRSHQQASASLSLQKRIRELQLRPDVLEQIAAASAVLRRVPGDASSLLFSEQGSDTPYWAKAVFLIPLGLLLGFFLFTQTVFGLAVMALFFSLILALQSRFNREMVLWRSQWGAVCALMNALQRLAQPCQIHIAGCENSADVERLARLIHKQISAKPSISIETEAYGNWFLLTNIKHHFKAMQNYRLHREFIRASFVQLGEIEAAYALVLHLQSVPYTTWMEWQQAETFHFDGVVHPLLENPQAISVNLTAPGMLITGQNAGGKSTFMRTLGLNMIVARAFGFCYAKQARAPYLPVYANMQNQDDLQGGESYYIAELRRAKELLNSAQNSGRGLYLIDEIFRGTNHIESVAAASSFLHALSKLAPVVAASHNIELAVILKERFQAMRFQHGTANKYQLEEGILELSNGLCLFEREDFGEEVNQGAVNALGFLQQHCRHPDLSKLVLPTLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZG7</accession>
    <name>A0A2S9GZG7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2207</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93121">
        <property type="protein sequence ID" value="PRC93121"/>
        <property type="gene ID" value="S2091_2207"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1010.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035996">
        <property type="entry name" value="4pyrrol_Methylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014777">
        <property type="entry name" value="4pyrrole_Mease_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014776">
        <property type="entry name" value="4pyrrole_Mease_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008189">
        <property type="entry name" value="rRNA_ssu_MeTfrase_I"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46111">
        <property type="entry name" value="PTHR46111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005917">
        <property type="entry name" value="MTase_YraL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53790">
        <property type="entry name" value="SSF53790"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="248" mass="26979" checksum="096F618A7EB7635F" modified="2018-07-18" version="1">MKNGTLYLLPNTLGIAHPSQPLFDVIPVEVQKITANLAYFVAENAKTTRAFLKLVNSNFPLAKPLQEIQISELNVNTKESALPDLLSPLLQGHDVGLISEAGVPAVADPGANLVKLAHQCGIKVRPMVGPSSLLLAVMASGLNGQSFAFNGYLPTDAALRSKRLQELELRSRKDKQTQLFIETPYRNAALLEAFCQSCNPATELCVATDLSLETEQIQTLPVSQWKALLAKGKMPDFNKKPTVFLFLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZI8</accession>
    <name>A0A2S9GZI8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">CRS1 / YhbY (CRM) domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_2230</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93144">
        <property type="protein sequence ID" value="PRC93144"/>
        <property type="gene ID" value="S2091_2230"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.110.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001890">
        <property type="entry name" value="RNA-binding_CRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035920">
        <property type="entry name" value="YhbY-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01985">
        <property type="entry name" value="CRS1_YhbY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01103">
        <property type="entry name" value="CRS1_YhbY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75471">
        <property type="entry name" value="SSF75471"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51295">
        <property type="entry name" value="CRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="CRM" evidence="4">
        <location>
            <begin position="2"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="129"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00626"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC93144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="158" mass="17136" checksum="7C431A639C95996A" modified="2018-07-18" version="1">MLKLTAIERSALRSEAHALNPIVLIGEAGLSEAVMKEIDNGLNSHGLIKVRVFGDDREARLAMYETICTTLKAAPIQHIGKLFVLFRPKLEGSVEKVLRKTGGGLREVTIVKPSPSGQKRPTVSKVMLKGNERVTQGGNIKRAKPRQASAKKSALKSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZJ9</accession>
    <name>A0A2S9GZJ9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ABC nitrate/sulfonate/bicarbonate family transporter, ATPase subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_2216</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93130">
        <property type="protein sequence ID" value="PRC93130"/>
        <property type="gene ID" value="S2091_2216"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018632">
        <property type="entry name" value="AAA-associated_dom_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09821">
        <property type="entry name" value="AAA_assoc_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-1278">Translocase</keyword>
    <feature type="domain" description="ABC transporter" evidence="7">
        <location>
            <begin position="18"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="55"/>
            <end position="62"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC93130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="442" mass="48939" checksum="09E60D4051CBDC62" modified="2018-07-18" version="1">MDQSAKQPTNTPANQALINLSGVSKNFRTADGSERVVLEGVDFTLKEGEIVALLGKSGSGKSTLLRIMAGLLPADKGQVIYRGQQLFGPARGIAMVFQSFALFPWLTVQQNVELGLEAQGIPKEIRAEQAEAAIEMIGLAGFEGALPRELSGGMKQRVGIARALVMKPDVLLMDEAFSALDVLTGETLRNDMLELWESKKTPMKGILIVSHNIEEAVMMADRILIFSSDPGRVRAEIKVSLPRDRSEDSPEVRALIDEVYTQMTTTPVESDFSGQSSAQNQAFRLPEAEISQMEGLLEMLADEPFNGRADLPKLAEEAGLSDDDLFPVYEALRLIGLVHIEHGDIHLTSLGQRYCQADQAFRKHLFGQQLLENVPLAARIHHSLKQEKSGEIRKEPFLNLLEEFLSAEEAKQMLEVAVEWGRYGEMYEYNYHTGMLKLPDAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZY5</accession>
    <name>A0A2S9GZY5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="8">2a37: transporter, monovalent cation:proton antiporter-2 (CPA2) family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_1996</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93258">
        <property type="protein sequence ID" value="PRC93258"/>
        <property type="gene ID" value="S2091_1996"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015299">
        <property type="term" value="F:solute:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006813">
        <property type="term" value="P:potassium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006153">
        <property type="entry name" value="Cation/H_exchanger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004771">
        <property type="entry name" value="K/H_exchanger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003148">
        <property type="entry name" value="RCK_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00999">
        <property type="entry name" value="Na_H_Exchanger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02254">
        <property type="entry name" value="TrkA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00932">
        <property type="entry name" value="2a37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51201">
        <property type="entry name" value="RCK_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0406">Ion transport</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="33"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="56"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="86"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="114"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="154"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="187"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="220"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="277"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="307"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="341"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="370"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="domain" description="RCK N-terminal" evidence="7">
        <location>
            <begin position="420"/>
            <end position="542"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC93258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="549" mass="58532" checksum="2DFDAB998F1B2FA1" modified="2018-07-18" version="1">MLHQTPLIATIIGGLVLAFIFGALANRLRMPPLIGYLVAGIVAGPFTPGFVADTHLAQELAEIGVILLMFGVGLHFSLKDLLAVKYIAIPGAVLQITFATLLGMGLAWGMGWTLGQGLIFGLALSCASTVVLLKALQDRRLVDTRRGQIAIGWLIVEDIMMVLALVLIPALSGLLGGTGEVLSTGEFLITLAITLGKVVAFVAVMLVFGKRAIPWILERVAATGSRELFGLSVLAIALGFALGSTYLFGVSFALGAFFAGMMLAESDLSHRAAEESLPLREVFSVLFFVSVGMLFDPSILLREPLMVVATVFIIVIGKSLVSMALVLAFRYPLSTALTISASLAQIGEFSFILATLGISLGILPPEGRDLILAGAIFSIILNPLVFFGVDYLKPWLDKREGYAKEPETENAAMCAQQQGHTILIGYGELGQLVGEELKAKHQPFIIVEDHPDIIHDTHLPDTPIVYGYASAPGVLDDAKIDSARCMVLTISDAIVAGQLITYARSLNPNITTIARASSDLEAEHLKEHGATHVIVSKREVAKNLAMLVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZY7</accession>
    <name>A0A2S9GZY7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2001</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93263">
        <property type="protein sequence ID" value="PRC93263"/>
        <property type="gene ID" value="S2091_2001"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007488">
        <property type="entry name" value="DUF535"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38785">
        <property type="entry name" value="PTHR38785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04393">
        <property type="entry name" value="DUF535"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="315" mass="35767" checksum="21EB8424833DA8A7" modified="2018-07-18" version="1">MHSGRKDASWKRAIRFMFHTMFHVKTSANWLRFLSGNSVLANSTTEATFFDRIHRPFFDKRSNTRQRTQLLLAHFDILTHILDAKQLQSVMSGSGINLASLIGKTGEVIDVNLTRFPDFDKEGGASLELTVDGKTILLLTFTLTRKYNNIALTIGGIQSREHAQTDCRTLLRDATHALHGIQPRILMIETLRSIAQQLACNTIECVNENNHIYRALRYRNKRVIHAQYNQLWLLVGGIEMTNGNFSIPSFVEEKSIESRPSKKRNEYRNRATLLHSVRTQVCEVIPPFSLINKNTNAAATVKIDAIFSNTTIEAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H041</accession>
    <name>A0A2S9H041_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Response regulator receiver domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2056</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93318">
        <property type="protein sequence ID" value="PRC93318"/>
        <property type="gene ID" value="S2091_2056"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002197">
        <property type="entry name" value="HTH_Fis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02954">
        <property type="entry name" value="HTH_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="3"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="248" mass="27584" checksum="BCF7AD0CACAECC1C" modified="2018-07-18" version="1">MANILVVDDEMGIRELLSEILGDEGHVVQSAENAQQARELRGLSRPDLVLLDIWMPDTDGVTLLKEWQRDGLLTMPVIMMSGHATIDTAVEATRIGALNFLEKPISLQKLLKAVQQGLTKTTEPQRGSLPNRMALTTDAGMVVSHQASYGNSSIQTTQIGTHHVVGGSFDARLAPAPMPLNPLSQFSFDLPLREARDSFERIYFEYHLQREGGSMTRVAERTGLERTHLYRKLKQLGVESLKSSKRHN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0Q2</accession>
    <name>A0A2S9H0Q2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltransferase domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1563</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93562">
        <property type="protein sequence ID" value="PRC93562"/>
        <property type="gene ID" value="S2091_1563"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_25" evidence="1">
        <location>
            <begin position="59"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="209" mass="24213" checksum="BFAF721AA62D1926" modified="2018-07-18" version="1">MLNKKTDLLTEIAEYYSTKLAEHGETPLGVDWNGEDSQLLRFEHLCKIIDPINRFSLNDLGCGYGALYDFLLKKYTQLSYSGIDVAEVMISAAEQRYKDQPLARFIISHEPDQIADYSVASGIFNVRLDKTDDEWLSYLKTTLDVLNHSSRKGFAFNCLTSYSDKDRMRDYLYYADPCILFDLCKSRYSRNVALLHDYGLYEFTILVRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0T0</accession>
    <name>A0A2S9H0T0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1569</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93568">
        <property type="protein sequence ID" value="PRC93568"/>
        <property type="gene ID" value="S2091_1569"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015578331" evidence="2">
        <location>
            <begin position="28"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="96"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="113" mass="12661" checksum="BBF302FE39243F71" modified="2018-07-18" version="1">MKNSTRIMMTLAAIATVSTLLASSAFADETQWQKDHPRRDQVNDRLANQNKRITKEVKEGEITKAQAHNLRANDKTIHGEEKAMASQDHGHITKTDQKALNQQLNQNSQAIGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H132</accession>
    <name>A0A2S9H132_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cation/multidrug efflux pump</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1654</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93653">
        <property type="protein sequence ID" value="PRC93653"/>
        <property type="gene ID" value="S2091_1654"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2090.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027463">
        <property type="entry name" value="AcrB_DN_DC_subdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001036">
        <property type="entry name" value="Acrflvin-R"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32063">
        <property type="entry name" value="PTHR32063"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00873">
        <property type="entry name" value="ACR_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00702">
        <property type="entry name" value="ACRIFLAVINRP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82714">
        <property type="entry name" value="SSF82714"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="335"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="361"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="387"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="432"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="467"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="554"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="896"/>
            <end position="919"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="926"/>
            <end position="944"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="950"/>
            <end position="976"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="997"/>
            <end position="1020"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1032"/>
            <end position="1055"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="1076" mass="117042" checksum="9FC7CAC54993FB13" modified="2018-07-18" version="1">MLWFVRIALKRPYTFVVLALLILIFGPLAALRSPTDIFPDIKIPVISAVWTYSGLSPEDMSGRVVYYYERQLSSTVNDIDHIESQSLAGYGIVKIFFQPNVDIRTATAQVTSISQTVLKQMPPGITPPLILNYNASTVPILQLALSSIQETEQKLFDFGQNFIRPQLATVPGTTIPSPYGGKVRQIQIDVNQEALQAKRLSAEDVENALAAQNQIIPVGTQKIGKFEYSVKLNNSPDAFEKLSDLPIKAVDGTIIYMRDIASIRDGNPPQTNIVRVNGSRAVLMTVLKSGAASTLDIVSNVKKLLPTIEETLPKSVHINAIGDQSIFVKAAVSGVAREAVIAALLTSLMILLFLGSWRSTLIITASIPLAILSSIAALYAMGETLNIMTLGGLALAVGILVDDATVTIENINWHLEQGKEVRTAIMDGAHQIVGPAFVSLLCICIVFIPMFFLSGVAHYLFVPMAEAVMFAMIASFILSRTLVPTMAAYLLRMHSIDGHPSGELLQMMQPNHITPSHSKNPLVRFQQAFERLFIRIRDVYYDFLRLAMENQRKFVIGFLSIVLLSFALVPWLGRDFFPAVDSGQIKLHVRAQIGTRIEETAKLFDQVEQQIRTTIPKEELGSIVDNIGLTVSGINQVYNNTGTIGPQDGDILISLNEGHAPTDDYVTKLRKQLSQQFPGTTFSFLPADIISQILNFGAPAPIDVQVMGPNGEANMAYAQKLLREISNISGIADTRIQQANNYPQLLVDVDRTRAKQMGITERDVTNSLVVTMAGSGQVAPAFWLNKRNGVSYPVVAQTPEYRIQTLSDLQNIPIAGDNVKGPQILGGLATITRSSTAAVVSHYAVQPAIDIFATPQHRDLGGVASDIERILKANEKDRPKGSTISLRGQVQTMNTAFSGLLFGLLAAVVLIYLLIVVNFQSWSDPFVIITALPAALAGIVWMLFATHTTLSVPALTGAIMCMGVATANSILVISFARERLQHTGNSTKAALEAGFTRFRPVVMTALAMIIGMAPMALGLGEGGEQNAPLGRAVIGGLMAATVATLFFVPIVFSMVHRHYQHTQSNENTSDGETNEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H133</accession>
    <name>A0A2S9H133_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RNA polymerase sigma factor RpoH</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">RNA polymerase sigma-32 factor</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rpoH</name>
        <name evidence="9" type="ORF">S2091_1690</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Interacts with the RNA polymerase core enzyme.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the sigma-70 factor family. RpoH subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93689">
        <property type="protein sequence ID" value="PRC93689"/>
        <property type="gene ID" value="S2091_1690"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009408">
        <property type="term" value="P:response to heat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00961">
        <property type="entry name" value="Sigma70_RpoH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000943">
        <property type="entry name" value="RNA_pol_sigma70"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009042">
        <property type="entry name" value="RNA_pol_sigma70_r1_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007630">
        <property type="entry name" value="RNA_pol_sigma70_r4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012759">
        <property type="entry name" value="RNA_pol_sigma_RpoH_proteobac"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00140">
        <property type="entry name" value="Sigma70_r1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04545">
        <property type="entry name" value="Sigma70_r4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000770">
        <property type="entry name" value="RNA_pol_sigma-SigE/K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00046">
        <property type="entry name" value="SIGMA70FCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02392">
        <property type="entry name" value="rpoH_proteo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00715">
        <property type="entry name" value="SIGMA70_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00716">
        <property type="entry name" value="SIGMA70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="2 6" id="KW-0346">Stress response</keyword>
    <keyword evidence="5 6" id="KW-0804">Transcription</keyword>
    <keyword evidence="1 6" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="RNA_pol_sigma70" evidence="7">
        <location>
            <begin position="89"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="domain" description="RNA_pol_sigma70" evidence="8">
        <location>
            <begin position="264"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="6">
        <location>
            <begin position="265"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Sigma-70 factor domain-2" evidence="6">
        <location>
            <begin position="65"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Interaction with polymerase core subunit RpoC" evidence="6">
        <location>
            <begin position="89"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS00715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS00716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC93689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="298" mass="33233" checksum="66DA5CF04C2AB6B5" modified="2018-07-18" version="1">MNHSTNALPLTSSNTALALGFTGTLGNIDAYISAVNRLPMLTHEEEIRLATALRDENDLAAAQQMVMSHLRLVVSIARGYLGYGLPHADLIQEGNIGLMKAVKRFDPDHGVRLVSYAMHWIKAEMHEYILKNWRLVKVATTKAQRKLFFNLRSHKLGFESMTQSQIDNLAETLNVKREEVIEMEMRLAGRDMALDAPTDDDDDKFAPIAYLASDNNEPTKVLEAQHYDQLQTVGLETALENLDARSRRIIEARWLANDDGSGATLHDLAAEFSVSAERIRQIESAALKKMKGSLAAYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H144</accession>
    <name>A0A2S9H144_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Cytochrome c oxidase subunit 1</fullName>
            <ecNumber evidence="8">7.1.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">S2091_1702</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>4 Fe(II)-[cytochrome c] + 8 H(+)(in) + O2 = 4 Fe(III)-[cytochrome c] + 4 H(+)(out) + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:11436"/>
            <dbReference type="Rhea" id="RHEA-COMP:10350"/>
            <dbReference type="Rhea" id="RHEA-COMP:14399"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="EC" id="7.1.1.9"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Energy metabolism; oxidative phosphorylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the heme-copper respiratory oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.1.1.9" evidence="8"/>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93701">
        <property type="protein sequence ID" value="PRC93701"/>
        <property type="gene ID" value="S2091_1702"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00705"/>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045277">
        <property type="term" value="C:respiratory chain complex IV"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004129">
        <property type="term" value="F:cytochrome-c oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015990">
        <property type="term" value="P:electron transport coupled proton transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006119">
        <property type="term" value="P:oxidative phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01663">
        <property type="entry name" value="Cyt_c_Oxidase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.210.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023616">
        <property type="entry name" value="Cyt_c_oxase-like_su1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036927">
        <property type="entry name" value="Cyt_c_oxase-like_su1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000883">
        <property type="entry name" value="Cyt_C_Oxase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023615">
        <property type="entry name" value="Cyt_c_Oxase_su1_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033944">
        <property type="entry name" value="Cyt_c_oxase_su1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014241">
        <property type="entry name" value="Cyt_c_oxidase_su1_bac"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10422">
        <property type="entry name" value="PTHR10422"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00115">
        <property type="entry name" value="COX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01165">
        <property type="entry name" value="CYCOXIDASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81442">
        <property type="entry name" value="SSF81442"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02891">
        <property type="entry name" value="CtaD_CoxA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50855">
        <property type="entry name" value="COX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00077">
        <property type="entry name" value="COX1_CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0186">Copper</keyword>
    <keyword evidence="7" id="KW-0249">Electron transport</keyword>
    <keyword evidence="7" id="KW-0349">Heme</keyword>
    <keyword evidence="8" id="KW-0408">Iron</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="42"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="83"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="127"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="166"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="204"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="251"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="287"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="321"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="357"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="391"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="437"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="476"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="domain" description="COX1" evidence="10">
        <location>
            <begin position="30"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC93701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="534" mass="59778" checksum="DA0470876EBAF215" modified="2018-07-18" version="1">MSNTTMDHAHAADHSHDHAHDDHPHGFRRWLFATNHKDIGTLYLIFALTMLFAGGTMALMIRAELFQPGLQFMQPEFFNQLTTMHGLVMVFGAIMPAFVGFANWMIPLQIGASDMAFARMNNFSFWLLPPAAILLMGSFWVPGGATAAGWTLYAPLSTQMGPGMDMAIFAIHIMGASSIMGSINIITTILNMRAPGMTLMKMPMFCWTWLITAYLLIAVMPVLAGAITMTLTDRHFGTSFFNAAGGGDPVMYQHIFWFFGHPEVYIMILPAFGIVSQIIPAFARKPLFGYASMVYATASIAILSFIVWAHHMFTTGMPVTAQLFFMYATMLIAVPTGVKVFNWIATMWQGSMTFETPMLFAIGFIFVFTIGGFTGLILAVTPIDIQMQDTYYVVAHFHYVLVAGSLFGLFAGFYYWSPKWTGFMYNETRGKIHFWSSLFWFNVTFFPMHFLGLAGMPRRYADYPAQFTDFNMLASVGAFFFGFTQLYFILFVVIPAYRGGKPAGDKPWEGAEGLEWTIPSPAPFHTFETPPTVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1J1</accession>
    <name>A0A2S9H1J1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Helix-turn-helix domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1464</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93855">
        <property type="protein sequence ID" value="PRC93855"/>
        <property type="gene ID" value="S2091_1464"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018062">
        <property type="entry name" value="HTH_AraC-typ_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00041">
        <property type="entry name" value="HTH_ARAC_FAMILY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="2">
        <location>
            <begin position="79"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="183" mass="19290" checksum="32B8A8B84345F789" modified="2018-07-18" version="1">MDSKDVNSLAKLQAFIDNALGISVGAPATASCPGATAATAVSLSALSAVGGSQLTANFLRMAIDGTPEYCRIAASLRRTEAYSMVSFLLQEGQGEKVRSLSARYGISAGHFRRIFRAALGGSPKSALNDWRLATAILALVERQQSVTEVAMAHGFASPSHFSSEVKKSLGQSLTHLFDAQKKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1L3</accession>
    <name>A0A2S9H1L3_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Translocator protein BipB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">S2091_1478</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Plays a role in the bacterium-induced formation of multinucleated giant cell (MNGC), which is formed after host cell fusion, as well as in the intercellular spreading of bacteria and in the induction of apoptosis in macrophages. May act in concert with other effector proteins to induce fusion of host cell membranes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Host membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the invasin protein B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93869">
        <property type="protein sequence ID" value="PRC93869"/>
        <property type="gene ID" value="S2091_1478"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033644">
        <property type="term" value="C:host cell membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006972">
        <property type="entry name" value="SseC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003895">
        <property type="entry name" value="T3SS_invasion_prot_B"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04888">
        <property type="entry name" value="SseC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01375">
        <property type="entry name" value="BACINVASINB"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="319"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="403"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="54"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="129"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="282"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010380"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00018823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00025490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC93869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="597" mass="63201" checksum="EDB927AE930A1D9D" modified="2018-07-18" version="1">MSAVIVNRRVENFLRDPSMVEKARDVTTMSPSILKEAERLADELAELITDELEEDQVSRKRRQSNAMRPQLAPPRQTGAEATAGTRDAGKMLASMLVLLEGAKLSKLAFNAYSAAVQGEARDAGNAKLVEDYESALNAVSEMVEQLAALKDQLAGLSDKAKALERQLADAEAALAELDPDTPEYEAAMSARDTLSSALAIVKSDLARVQGEVRAMQSGVAELQKIADDLFVRAGQAGVDLPRTVVEKDVSNIARMLALMTQLGELMLEVGETLFAVQRELLKVQEDARITQLNKDAEKAEKEMAKAEALNKAMGCVGKILGAIVTAVSLVGAIFTGGASLALAGIGLALMMADEIYKGVTGNSFMEEAFKPLMKVLEPILQYVMNIVSDMLVGLGVDAQTAKMAAMIVVSVVIAAAVVALAVTGAGSAIAKVASSAAKQVSKVLTKVMEKTIAKLVPQMLKKSIAQMTKKMSGTTSKMFDAVSQRLGLSTDVASKQIYASNLGRVAAGVNFGKTVITSGLDVGAQVANKEVEESVVSMDRVMFLQEQGRKATDDLVARLIKSSSSWGEPFAFISEAIGQSTSVAVAVIRAIRGGRAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1R8</accession>
    <name>A0A2S9H1R8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1107</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC93934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93934">
        <property type="protein sequence ID" value="PRC93934"/>
        <property type="gene ID" value="S2091_1107"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="34" mass="3891" checksum="7454D25960EDCC7E" modified="2018-07-18" version="1">MWLIFVEATGAFLVFALIVWWTMFSGAKPPSDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1S9</accession>
    <name>A0A2S9H1S9_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Flagellar basal body protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_1526</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 4">Bacterial flagellum basal body</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the flagella basal body rod proteins family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93917">
        <property type="protein sequence ID" value="PRC93917"/>
        <property type="gene ID" value="S2091_1526"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009425">
        <property type="term" value="C:bacterial-type flagellum basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.98.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037058">
        <property type="entry name" value="Falgellar_hook_FlgE_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001444">
        <property type="entry name" value="Flag_bb_rod_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019776">
        <property type="entry name" value="Flagellar_basal_body_rod_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020013">
        <property type="entry name" value="Flagellar_FlgE/F/G"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010930">
        <property type="entry name" value="Flg_bb/hook_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037925">
        <property type="entry name" value="FlgE/F/G-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00460">
        <property type="entry name" value="Flg_bb_rod"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06429">
        <property type="entry name" value="Flg_bbr_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117143">
        <property type="entry name" value="SSF117143"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03506">
        <property type="entry name" value="FlgEFG_subfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00588">
        <property type="entry name" value="FLAGELLA_BB_ROD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0975">Bacterial flagellum</keyword>
    <keyword evidence="7" id="KW-0966">Cell projection</keyword>
    <keyword evidence="7" id="KW-0969">Cilium</keyword>
    <keyword evidence="7" id="KW-0282">Flagellum</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flg_bb_rod" evidence="5">
        <location>
            <begin position="7"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="domain" description="Flg_bbr_C" evidence="6">
        <location>
            <begin position="316"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU362116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF06429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC93917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="397" mass="40366" checksum="57A170663BC0BDDE" modified="2018-07-18" version="1">MSLSSSIDIGMSGLLGFSQELQTISNNVANLNTPGFKGSDSQFSDLFSQDNSFSGGSGDSTGGGMQVLPAVINFSQGQTTQTGVATNMVDSGNSFFVLKDPKTGQISYTQDGQFQFNSSGVLVDSTGNFDVQALDSSGKLANLTQSGLQNSLPKASSTITLAGNLSTTTSPDVVSSINVTDAAGGTHTLTATFTNSTKTPGTWTVSLADANGTVSSGGSFVFTNGTLTTTGGANSYAFTYSPAGVPAMNLTLTLDPSSTYLASSSTLGVESVDGYAAGTVTNATFNQSGTLVLSYSNGQTVNGPNVALANFSSTANLQHAGNNAFITSNNGDAQLGIAGNTSAWGTINSGSIQASNVDLSTEFSNIIITQRGYQAASEIVSTANQMMQNVLDMKGQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1U4</accession>
    <name>A0A2S9H1U4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">RF-1 domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1445</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93836">
        <property type="protein sequence ID" value="PRC93836"/>
        <property type="gene ID" value="S2091_1445"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003747">
        <property type="term" value="F:translation release factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000352">
        <property type="entry name" value="Pep_chain_release_fac_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00472">
        <property type="entry name" value="RF-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00745">
        <property type="entry name" value="RF_PROK_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RF_PROK_I" evidence="2">
        <location>
            <begin position="19"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="108"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS00745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="135" mass="15036" checksum="E4EF1583EE354E2F" modified="2018-07-18" version="1">MTLSEINIPLAEIELSAIRAQGAGGQNVNKVSSAVHLRFDVINSSLPDELKQRILESGDQRITKNGVIVLKAQSHRTQERNKEDALQRLHEIVQEAAYVAKVRYPTKPGKAAKTRRLDGKTQRGQVKSLRSKVIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1W9</accession>
    <name>A0A2S9H1W9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyl transferases group 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1123</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC93950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93950">
        <property type="protein sequence ID" value="PRC93950"/>
        <property type="gene ID" value="S2091_1123"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="210"/>
            <end position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="391" mass="43845" checksum="974F087FAF86F965" modified="2018-07-18" version="1">MKILFNADAIRYPLTGIGRYAHELGNRLPKAEEIEKVLYFRDGALHSDLSIRPNTGNHSEKARVRLRRWAGSMPLISKAYHKLIAKQQERAACKLKDEGYIYHGPNYYLPEFSGPCVATFHDLSIFLWPECHPEARVRHMSKELPLTIKRAQVLLTDSEFTRQEIASYFNFPLDRIVTAPLAASPDYRPMSAFEVAPVLSTLKLNYGSYSLFVGTLDPRKNIDILIDVYERMPDALRQRIPLIVAGFEGWHSEKTIERLKAGEHAGWARYLGFVDEAALPSLYAGARVFLFPSRYEGFGLPVLEAMAAGVPVICSNAASLPEVTGTDGATLIPADDVDQLYDAIVRALEDDTWCVAARERGINRASHFSWDKTAAATITAYKLAQKIKQQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1X0</accession>
    <name>A0A2S9H1X0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Bacterial membrane protein YfhO</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1130</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC93957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93957">
        <property type="protein sequence ID" value="PRC93957"/>
        <property type="gene ID" value="S2091_1130"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018580">
        <property type="entry name" value="Uncharacterised_YfhO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38454">
        <property type="entry name" value="PTHR38454"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="30"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="150"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="203"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="249"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="309"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="340"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="370"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="410"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="433"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="756"/>
            <end position="776"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="795" mass="87390" checksum="6824C39B9A207AD4" modified="2018-07-18" version="1">MKFIAPLHQKSDSVSTLTNSPNKPLISIRSLWLGMVLITILALIMWRFPLFTPSSVFHGDMIGFGLPLFNLAGRAFSGHASLLWASGVYGGHPIFAEGQGAFANPLTFLIGTIITPIAGPIFAMNFFQFICLLLTGAGMLGLCRQIGFSAVASAFSALAVTFSPFWIYTILDNPVGTGTFLWVPWCLWSLEKWLQQPNLRSSVFLGSTCTAMLLAGYTPGFHATVLYMGVRVIADAFNENTRNIWINTWSIRIATGIAAILICIGLSAIQWLPLLELIAQSHRNDGTGLTLIVDVTTTLRGMFYGNPRAVSFVNIGSPLILALALCALSGVRSIRITGHLFAAIILIQLGCNSPFFRFVYDHNLIPGIHYVRITFQFLIPGIIGIILIAGSSIDAFNPWFSMQTRARRSAILFGVALVWITAAATLYTPDIAIIQLGIAITAFITVTILLSSKYGRFVPITLLFLLTVECSMRLNPFQTANNDNFKIPTSVLAIKSTKNWQDYKVLDTTVALGYAFHDPHTPNLTAEMKVMLYSLSGLTSTLWGINSMDGALALPLKRHTLLTNPILNEINGTSSLPPGLRLIDTLGIRYISTHEPAKDDLAFRTFLHSDGFPWIIENTAAMPRFQIYQDHVTVDSPEAALAVMQTWTKRTLVIENAAGSNHQIEPSDFVSRQPIAADSPSPANFEIIKASDTHYHLNLHATKPCWLFLADANYPGWKAYLDGKPVPVFSAQVQGKAVAIPEGQHQLEFTFESSSFRWGACISFITLMLTTVALLLDWRKRIMGLQLTNKISGNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2E4</accession>
    <name>A0A2S9H2E4_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_1322</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94149">
        <property type="protein sequence ID" value="PRC94149"/>
        <property type="gene ID" value="S2091_1322"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004673">
        <property type="term" value="F:protein histidine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Histidine kinase" evidence="3">
        <location>
            <begin position="1"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC94149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="169" mass="18576" checksum="4810913BE8255C4A" modified="2018-07-18" version="1">MAALERTQQNHVVTHPCVLADIVKQVLEELAPLAQHKNSDLGIDNLDETVLISAPVYLLHELVLNLVENAIQHMTKSGVVTISILREKNNCIFRVVDNGPGIPESERKNVLQRFYRLDASQSTSSGLGLSIANEIALSINAQLVLTTPLSGQGLQVDMRFISTIFTRPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2H2</accession>
    <name>A0A2S9H2H2_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">50S ribosomal protein L7/L12</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rplL</name>
        <name evidence="7" type="ORF">S2091_1330</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the bacterial ribosomal protein bL12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94157">
        <property type="protein sequence ID" value="PRC94157"/>
        <property type="gene ID" value="S2091_1330"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00387">
        <property type="entry name" value="Ribosomal_L7_L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.710">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00368">
        <property type="entry name" value="Ribosomal_L7_L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000206">
        <property type="entry name" value="Ribosomal_L7/12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014719">
        <property type="entry name" value="Ribosomal_L7/12_C/ClpS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013823">
        <property type="entry name" value="Ribosomal_L7/L12_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008932">
        <property type="entry name" value="Ribosomal_L7/L12_oligo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036235">
        <property type="entry name" value="Ribosomal_L7/L12_oligo_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45987">
        <property type="entry name" value="PTHR45987"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00542">
        <property type="entry name" value="Ribosomal_L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16320">
        <property type="entry name" value="Ribosomal_L12_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48300">
        <property type="entry name" value="SSF48300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54736">
        <property type="entry name" value="SSF54736"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00855">
        <property type="entry name" value="L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Ribosomal_L12_N" evidence="6">
        <location>
            <begin position="5"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="domain" description="Ribosomal_L12" evidence="5">
        <location>
            <begin position="57"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007197"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF16320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC94157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="123" mass="12469" checksum="6ABE60A84C4C5F13" modified="2018-07-18" version="1">MAISKDDILEAVGAMSVMDLNDLVKAFEEKFGVSAAAMAVAGPAAGGAAAAEEQTEFNVILTEIGANKVGVIKAVRELTGLGLKEAKDVVDGAPKAVKEAVSKADADAAKKKLEEAGAKAEIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2I9</accession>
    <name>A0A2S9H2I9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">4HPPD: 4-hydroxyphenylpyruvate dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_0822</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
        <text evidence="5">Binds 1 Fe cation per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the 4HPPD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94201">
        <property type="protein sequence ID" value="PRC94201"/>
        <property type="gene ID" value="S2091_0822"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003868">
        <property type="term" value="F:4-hydroxyphenylpyruvate dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009072">
        <property type="term" value="P:aromatic amino acid family metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07250">
        <property type="entry name" value="HPPD_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd08342">
        <property type="entry name" value="HPPD_N_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005956">
        <property type="entry name" value="4OHPhenylPyrv_dOase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041735">
        <property type="entry name" value="4OHPhenylPyrv_dOase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041736">
        <property type="entry name" value="4OHPhenylPyrv_dOase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004360">
        <property type="entry name" value="Glyas_Fos-R_dOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11959">
        <property type="entry name" value="PTHR11959"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00903">
        <property type="entry name" value="Glyoxalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF009283">
        <property type="entry name" value="HPP_dOase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01263">
        <property type="entry name" value="4HPPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="4 5" id="KW-0408">Iron</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="VOC" evidence="6">
        <location>
            <begin position="14"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="domain" description="VOC" evidence="6">
        <location>
            <begin position="169"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="172"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="250"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="331"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR009283-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC94201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="370" mass="41641" checksum="377A01DCF35B61DC" modified="2018-07-18" version="1">MEFKGWENPMGTDGFEFIEYAAPDPKALGALFEQMGFMAIARHRHKDVTLYRQGDINFIINAEPDSFAQRFARKHGPSVCAFAFRVNDAAAAYKRALELGAWGFDNKTGPMELNVPAIKGIGDSLIYFVDRWRGKTGEAGAIGDISIYDADFVAIPGTPLNPVGHGLTYIDHLTHNVHRGRMKEWAEFYENYFGFREVRYFDIEGKMTGLKSKAMTSPCGKIRIPINESSDDKSQIAEYLDLYHGEGVQHIALGSDDVYSSVASMKKAEVAFQDTIETYYDLIDRRLPGHGENLARLRELRILVDGTSTETKRELLLQIFTQTVIGPIFFEIIQRKGDEGFGEGNFRALFESIELDQIRRGVLKEEPAKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2S8</accession>
    <name>A0A2S9H2S8_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Glutaredoxin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_0864</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the glutaredoxin family. Monothiol subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94243">
        <property type="protein sequence ID" value="PRC94243"/>
        <property type="gene ID" value="S2091_0864"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097573">
        <property type="term" value="F:glutathione oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03028">
        <property type="entry name" value="GRX_PICOT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002109">
        <property type="entry name" value="Glutaredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033658">
        <property type="entry name" value="GRX_PICOT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014434">
        <property type="entry name" value="Monothiol_GRX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004480">
        <property type="entry name" value="Monothiol_GRX-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10293">
        <property type="entry name" value="PTHR10293"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00462">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005894">
        <property type="entry name" value="Monothiol_GRX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00365">
        <property type="entry name" value="TIGR00365"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="4 7" id="KW-0408">Iron</keyword>
    <keyword evidence="5 7" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutaredoxin" evidence="8">
        <location>
            <begin position="17"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="30"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR005894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR005894-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC94243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="103" mass="11316" checksum="0CE23B34CD03D7FF" modified="2018-07-18" version="1">MNDVQSWIKETVTNNQVVLFMKGTAQFPQCGFSGRAVQILKACGVENLVTVNVLEDADVRQGVKDFSNWPTVPQLYVKGEFIGGSDIMGEMYDSGELKALIQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2T6</accession>
    <name>A0A2S9H2T6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Methyl-accepting chemotaxis protein (MCP) signaling domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_1349</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyl-accepting chemotaxis (MCP) protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94176">
        <property type="protein sequence ID" value="PRC94176"/>
        <property type="gene ID" value="S2091_1349"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004888">
        <property type="term" value="F:transmembrane signaling receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004090">
        <property type="entry name" value="Chemotax_Me-accpt_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024478">
        <property type="entry name" value="HlyB_4HB_MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004089">
        <property type="entry name" value="MCPsignal_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12729">
        <property type="entry name" value="4HB_MCP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00015">
        <property type="entry name" value="MCPsignal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00260">
        <property type="entry name" value="CHEMTRNSDUCR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00283">
        <property type="entry name" value="MA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50111">
        <property type="entry name" value="CHEMOTAXIS_TRANSDUC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0807">Transducer</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="192"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="6">
        <location>
            <begin position="213"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="domain" description="Methyl-accepting transducer" evidence="5">
        <location>
            <begin position="270"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="558"/>
            <end position="580"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00029447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC94176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="580" mass="61970" checksum="1A75F069B7F426F0" modified="2018-07-18" version="1">MLSFKDLKISSKLLVSASLSVFLAILVGVFSITQLAKVNQATDDLGNNWMPSAVSILQVKANMASYRAQELEHVLAKDEAGKAKYEQRLETYLSNAKKNRDIYEKLLTFPDEKAKFAEYLTLWDQYLAVHSKIIALSNQNKIDEAMVLMGTESSQANSKMIQLVNDMADINTNAGARSYTDSVQTYQSSRTWIIGLLLVSVAVNLVFSIWINRLISIPMQEALQVAQTVASGDLTSHIVVSSKDETGHLLQALHDMNAHLNEVMGEVRASSETIAVATSQIAAGNMDLSQRTERQAGSLEETAASTEELTSTVKQNLDNARQANQFSIAASEVAVRGGKVVSDVVSTMGEIDASARKIVDIIGVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVASEVRNLAQRSASAAKEIKELIGNSVEKVQEGSRLVNHAGSTMEEVVSSIQKVTTIMADITIASQEQSSGVQQVNDAIMQMDQVTQQNAALVEEAAAAASSMEQQTSVLNKLVGQFKLSGGGGRVAARATTVASPKKVTATVRPVVKVPNKPAAMARLVANKNAAAPATSSAASKADPGDWEEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2U1</accession>
    <name>A0A2S9H2U1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Metallo-beta-lactamase superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0909</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94288">
        <property type="protein sequence ID" value="PRC94288"/>
        <property type="gene ID" value="S2091_0909"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015547540" evidence="1">
        <location>
            <begin position="40"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="domain" description="Lactamase_B" evidence="2">
        <location>
            <begin position="88"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="333" mass="36827" checksum="3CB226D9D8A3C4DE" modified="2018-07-18" version="1">MKTATPHFFTLSRPIRPTWCRTMLALVMLALFTTLSCQAQDVIPLLLTTKFSPGASDCDHNPPPPLEIRQFDATTYVLRESLCVTDEAPFMYLIIGSTRALLIDTGDVADPKKMPLAQTVLRLLPAKAGLTLPLLVAHSHRHSDHREGDVQFRGLPNVEVIGHDIDSVKTYFGFVDWPNGEAHIDLGGRIVDVIPTPGHNETHVAFYDRTTALVFSGDFLMPGRLLINDKQADLASARRMAAFASQHLVSYVLGGHVEINDAGETFSWGATMHANEHVLPLTKKDLMALPEAVEHFNHFYTHYGSFIMQDQLFVPPFLTLAAPDSLVLLGSTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2X2</accession>
    <name>A0A2S9H2X2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0928</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94307">
        <property type="protein sequence ID" value="PRC94307"/>
        <property type="gene ID" value="S2091_0928"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015671142" evidence="1">
        <location>
            <begin position="24"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="194" mass="22116" checksum="64FAD250A9D07878" modified="2018-07-18" version="1">MNWYRTLITLAMCLLIAPNFVSAQATTPTTVEIQPALHDGQHDFDFYFGSWKQHLKRLIHPLTGSTTWAEFDGTIVVRRVWDGRANLNEFEGEGPSGHIEGLTLRLYNPQTHQWSLYWANSKDGAIGGPPSVGEFKNGRGEFFCQDTLNGRAIFIRYIWSDITPNSAHFEQSYSDDGGKTWEVNWISTMTRLQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H339</accession>
    <name>A0A2S9H339_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1001</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94380">
        <property type="protein sequence ID" value="PRC94380"/>
        <property type="gene ID" value="S2091_1001"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018673">
        <property type="entry name" value="DUF2141"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09912">
        <property type="entry name" value="DUF2141"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015689959" evidence="1">
        <location>
            <begin position="23"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="141" mass="14666" checksum="24B7C2AD3B384E31" modified="2018-07-18" version="1">MKRILKMALLSALVASAASASAATLQVKIDGVASGKGKLRVAVCDESTFLKKCTIGALAPAHTGSVTVDVPDVPTGNWAVMAYHDENDNQKLDRDEMGIPTEGYGFSNGATAKYGPPQFRQAAVIVSAGATAVPVQITLKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H340</accession>
    <name>A0A2S9H340_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphopantetheine attachment site</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1012</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94391">
        <property type="protein sequence ID" value="PRC94391"/>
        <property type="gene ID" value="S2091_1012"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="1">
        <location>
            <begin position="5"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="120" mass="13259" checksum="5C02B42431E1D158" modified="2018-07-18" version="1">MNANQISQIAASVLYLDDANAIDTGKSLFKEYGMSSLDFVDFAYELKAAANKEFDPDQLWPINVMMNNPVFYAGGSWTDAGRAELVRLFDGYTTVPASGGTEELYALFSVGYVEHRLRAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3A3</accession>
    <name>A0A2S9H3A3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1058</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94437">
        <property type="protein sequence ID" value="PRC94437"/>
        <property type="gene ID" value="S2091_1058"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="47" mass="5596" checksum="336E75E236930E14" modified="2018-07-18" version="1">MLVVAAWSLMDMVGGWAKLEPLNNPNYRQKIIEWLQRKLNRINSRQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3B3</accession>
    <name>A0A2S9H3B3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1096</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94475">
        <property type="protein sequence ID" value="PRC94475"/>
        <property type="gene ID" value="S2091_1096"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="82" mass="9252" checksum="46DC8F5F7AB554BF" modified="2018-07-18" version="1">MTACYPGHAEAIRSKVSPNSWNHLHHVAGDKSVDVSPFLDEGRLLPNDSPHYNNAFNGFATSYFYYSVLREAQDWQGLAVPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3B7</accession>
    <name>A0A2S9H3B7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Pro-kumamolisin, activation domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0977</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94356">
        <property type="protein sequence ID" value="PRC94356"/>
        <property type="gene ID" value="S2091_0977"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11377">
        <property type="entry name" value="Pro-peptidase_S53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015366">
        <property type="entry name" value="S53_propep"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09286">
        <property type="entry name" value="Pro-kuma_activ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00944">
        <property type="entry name" value="Pro-kuma_activ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015504157" evidence="1">
        <location>
            <begin position="23"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="domain" description="Pro-kuma_activ" evidence="2">
        <location>
            <begin position="40"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="189" mass="19765" checksum="7797973CF749DE5A" modified="2018-07-18" version="1">MKLKTNLITIFATALITHYVVAAAQPNTVWVPIQSHTPDVSMAKPGAVMNADEALHITVSLQVRDKAGLDALTSGVTAGASPAPLTSAQFQSKYAPADDAVSAVVAYLSKNGFSNITVASNHLLITANGNVGAAKSAFHVNMQHFSVGGRDAYANVNDPVVPKELGTIVLAVQGLQNVHMPHTMLKAKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3G0</accession>
    <name>A0A2S9H3G0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1094</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94473">
        <property type="protein sequence ID" value="PRC94473"/>
        <property type="gene ID" value="S2091_1094"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="9"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="156" mass="17580" checksum="4576A77F7ED7C429" modified="2018-07-18" version="1">MGNLMKYQALIRKFEHRDLNELAQLFDAYRQFYEQAPDLALAEHYLATRVEKRESVILVAENSAGGLSGFCQLYPTFCSVLAQPIYVLYDLFVSPEARGNGVAKHLLNAARELGISDGKARLDLTTAKTNSTAQSLYASLGWVRDEEFYTYNLTLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3G4</accession>
    <name>A0A2S9H3G4_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF2846 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0528</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94525">
        <property type="protein sequence ID" value="PRC94525"/>
        <property type="gene ID" value="S2091_0528"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022548">
        <property type="entry name" value="DUF2846"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11008">
        <property type="entry name" value="DUF2846"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015449928" description="DUF2846 domain-containing protein" evidence="1">
        <location>
            <begin position="29"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="domain" description="DUF2846" evidence="2">
        <location>
            <begin position="40"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF11008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="511" mass="54069" checksum="620C9FDC8C5D40C0" modified="2018-07-18" version="1">MKRIVGIFIAAMVVLLTGCASVPMASLAQDSKAKEFTPDQNKASLYIYRNETIGAAISMPVSVNGATIGETASKTYFQLDLLPGAYNLKSEAENDSNLALTLIAGKNYFVWQEVKMGIFSARNKLQLVDDETGRAGVTESKLILISSSAYKTPAVNQHDDKTPLAVVAPMVASAPITTIAADATVATNVQQSIPSSPLSSDPVAAKKVEFNFGQSSITVEKMAKQQNCNPGVGANLISKNGVEEQYSVKCSDGRELKAQCEYRQCAFTTQNTPVAAVTPVAPVAVISTVTIAPSTAQAAPTTSVTLATNSSIPASDNSNAVISTPVATQNTAPEPVMEAPQPEKQLNIVLGLGLTAGGDNLETTTYTNGSTSSIHAGSGVQFLTGLDYRINDSFSVQGTVGFQDMVSAARNGNVSFTRFPIELLGYYSLNKSWRIGGGVRFVQDPTLSGNGIGSNISVDFNNTVGSVLEVEYLANKHLGFKFRAVKESFTAVGQTESVNGDQFGFFTNFYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3P6</accession>
    <name>A0A2S9H3P6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0608</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94605">
        <property type="protein sequence ID" value="PRC94605"/>
        <property type="gene ID" value="S2091_0608"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="3"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="299" mass="32887" checksum="61A0D0E06292CEC3" modified="2018-07-18" version="1">MIDRFTSMSVFVRVANKGSFAAAAEGLGLTPAMVGRHVRYLEDWVGAALLNRTTRRQSLTELGQLFLERAQNILTEVELTEGMLDSARVLPSGTLRVTAPISFGEVLAPALVDYSLLYPKVTIDLNLSDSLVDVPGEGFDIAIRTGPLADSGLISRSLAPYRFLLCAAPSYLAKFPAPKEPEDLQQHRCLAFSGWMDGVDWTFLRADGVERHVRIQSQIRINNRVAMRAAAMAGGGIVMQPMASLALAVEEGSLVRLLPEWAPPSKQLHLVWAQNRHITQKLRTFIDFAVARFGEQESV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3S5</accession>
    <name>A0A2S9H3S5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Xth: exodeoxyribonuclease III (Xth)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0614</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA repair enzymes AP/ExoA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94611">
        <property type="protein sequence ID" value="PRC94611"/>
        <property type="gene ID" value="S2091_0614"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008853">
        <property type="term" value="F:exodeoxyribonuclease III activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004808">
        <property type="entry name" value="AP_endonuc_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020847">
        <property type="entry name" value="AP_endonuclease_F1_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22748">
        <property type="entry name" value="PTHR22748"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="SSF56219"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00633">
        <property type="entry name" value="xth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00726">
        <property type="entry name" value="AP_NUCLEASE_F1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51435">
        <property type="entry name" value="AP_NUCLEASE_F1_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Endo/exonuclease/phosphatase" evidence="2">
        <location>
            <begin position="6"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007092"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="256" mass="28813" checksum="9CBCC5714B3762C4" modified="2018-07-18" version="1">MMKIISANLNGIRSAAKKGFFEWMAAESADFVCVQELKAQVGDMQPEFLAPGGYHGHFHYAQKKGYSGVGVYSKQEPNAVYIGFGNEEFDAEGRYVRCDFGKLSVISLYCPSGSSGEERQAAKFRFMDVFLAHLNELKASGQEIVICGDWNIAHKEIDLKNWKGNLKNSGFLPEERAWFSHVIGEVGYVDAFRCVEPAAEQYTWWSNRGQAWAKNVGWRIDYHVTTPAIAAKAKRVAIYKEQRFSDHAPLTIEYSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H483</accession>
    <name>A0A2S9H483_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Lipopolysaccharide export system ATP-binding protein LptB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">S2091_0795</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. Probably responsible for energy coupling to the transport system.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12">Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell inner membrane</location>
            <topology evidence="3">Peripheral membrane protein</topology>
            <orientation evidence="3">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the ABC transporter superfamily. Outer membrane lipopolysaccharide export (TC 1.B.42) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94792">
        <property type="protein sequence ID" value="PRC94792"/>
        <property type="gene ID" value="S2091_0795"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03218">
        <property type="entry name" value="ABC_YhbG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032823">
        <property type="entry name" value="BCA_ABC_TP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030921">
        <property type="entry name" value="LPS_export_LptB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12399">
        <property type="entry name" value="BCA_ABC_TP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04406">
        <property type="entry name" value="LPS_export_lptB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-1278">Translocase</keyword>
    <feature type="domain" description="ABC transporter" evidence="14">
        <location>
            <begin position="5"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="37"/>
            <end position="44"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00024818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00026081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="PRC94792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="247" mass="27391" checksum="BD32E88F74BD7808" modified="2018-07-18" version="1">MNSHLQVQGLQKHYGARQVVRDVSIDVTSGEVVGLLGPNGAGKTTSFYMIVGLVPSDAGIIKLNDVDISNLPIHKRARLGLSYLPQEASVFRKLSVEDNIRAVLELQRDEQGNPLSKDAIDDRLNTLLGELQIEKIRENMALSLSGGERRRVEIARALATNPRFVLLDEPFAGVDPIAVIEIQRIVRFLKERNIGVLITDHNVRETLGICDRAYIINQGAVLASGHPDDIISNESVRRVYLGDHFRM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4E0</accession>
    <name>A0A2S9H4E0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">WYL domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0749</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94746">
        <property type="protein sequence ID" value="PRC94746"/>
        <property type="gene ID" value="S2091_0749"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026881">
        <property type="entry name" value="WYL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016634">
        <property type="entry name" value="WYL_dom_s026"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13280">
        <property type="entry name" value="WYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015558">
        <property type="entry name" value="Txn_reg_DeoR_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WYL" evidence="1">
        <location>
            <begin position="121"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="291" mass="33262" checksum="D9BEF2C3D7EEB852" modified="2018-07-18" version="1">MNIRSIENFAQTQRDRLAFIEFRLWFLGDISRRDLMERFGIAPAMATRDLAAYRDLAPGNIDFEGSRKIYVTGRNFSPLFEHDAERILSALSKGFGDGTSEATQGYLPFESPLRLNRPSLPVLATISRAIHQQMVVRVKYHSLKRGPSKREIIPHALVDSGLRWHVRAYDRRLAQFRDLVLSRIEAPILQADSIVEEHELCDRDDQWTRIVALELVPHPNHAWKEIVARDFGMTKDKLIVKVRAAIAGYLLRLWNVDCSADNHLDPAIHRLWLRNTNVLRGVISAEIAPGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4H1</accession>
    <name>A0A2S9H4H1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0080</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DinB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94885">
        <property type="protein sequence ID" value="PRC94885"/>
        <property type="gene ID" value="S2091_0080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007837">
        <property type="entry name" value="DinB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034660">
        <property type="entry name" value="DinB/YfiT-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37302">
        <property type="entry name" value="PTHR37302"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05163">
        <property type="entry name" value="DinB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109854">
        <property type="entry name" value="SSF109854"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="168" mass="19431" checksum="45665803B9D47618" modified="2018-07-18" version="1">MTELNNIRMLTRYKAWANKIIYETVASLPADEATKERPTRFKNMVHTLNHIYVIDHIFQAHLEGRKHDYQARNTPTHPPLEQLWQSVQVLDNWYVELSDKLTADALGEMINFHFVDGGAGRMTRAQMILHVVNHGTYHRGFVGDMLYQVPVIPPATDLPVFLRDVPQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4J2</accession>
    <name>A0A2S9H4J2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0097</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94902">
        <property type="protein sequence ID" value="PRC94902"/>
        <property type="gene ID" value="S2091_0097"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="200" mass="22347" checksum="213A48E86872B60E" modified="2018-07-18" version="1">MLTSKNKRNINAAGTSDTPKLTRIERTQQIADIVLKILSCIAIVATGIWAYYQYYIKGANDWMVNLTITTEVLPYQEKLRLLVVHIKSKNPTSAKLDFEKEKGTFDLIVRKLPDKLKEGSTLDEITGEKIAEIDLLTEDLEILPSAEFDNMKTIVVPVGSTLSLTSAMEYENGTLTKEGKPDHDFVSASTVIHIDDKKSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H544</accession>
    <name>A0A2S9H544_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Outer membrane protein assembly factor BamE</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">bamE</name>
        <name evidence="7" type="ORF">S2091_0299</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the Bam complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the BamE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95104">
        <property type="protein sequence ID" value="PRC95104"/>
        <property type="gene ID" value="S2091_0299"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043165">
        <property type="term" value="P:Gram-negative-bacterium-type cell outer membrane assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051205">
        <property type="term" value="P:protein insertion into membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1450.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00925">
        <property type="entry name" value="OM_assembly_BamE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026592">
        <property type="entry name" value="BamE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037873">
        <property type="entry name" value="BamE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007450">
        <property type="entry name" value="Lipoprotein_SmpA/OmlA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37482">
        <property type="entry name" value="PTHR37482"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04355">
        <property type="entry name" value="SmpA_OmlA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="2 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015791319" description="Outer membrane protein assembly factor BamE" evidence="4">
        <location>
            <begin position="28"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="domain" description="SmpA_OmlA" evidence="6">
        <location>
            <begin position="94"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="47"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC95104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="202" mass="22385" checksum="E473BD5722C34350" modified="2018-07-18" version="1" precursor="true">MRMLQNCNTKYYLMLSMFVLISGCASQNPPVQDSSIAASQTTAPATPAAAAPVATSGSSESSDPDHLSTKTVAPVGFEKFMGIFTPYRITIQQGNFVSQEMVAQVKEGMTREQVRFLLGTALLTDMFHADRWDYIFRLLKPSGELITSRVTVTFSKSLVSKIERGELPNEQEYLTRITNAAIVDTIEHTDRKADKPKPKKDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H594</accession>
    <name>A0A2S9H594_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0355</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95160">
        <property type="protein sequence ID" value="PRC95160"/>
        <property type="gene ID" value="S2091_0355"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002123">
        <property type="entry name" value="Plipid/glycerol_acylTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01553">
        <property type="entry name" value="Acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00563">
        <property type="entry name" value="PlsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="domain" description="PlsC" evidence="2">
        <location>
            <begin position="86"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC95160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="257" mass="28927" checksum="B1502C70917F1CE1" modified="2018-07-18" version="1">MLERAFYGWRLLATGFCFAVFGIGGLFLRVLVCPLLNLLVWNRAYRTALARTMIRVAFRFFVGLMQGLGVLRYEIIGRQRLDRSGLLILANHPTLIDTVFLMAFVKRADCIVKADLQTNLFTRGAVIAAGYIFNNHGSELVNDCINSLECGSNLIVFPEGTRTPSDGQICLKRGAANIAVRAKCNVTPVVITCYPKTLSKGEKWWQIPLRPATFRIEVKDDIEIDQFTNNAVSDVMSARHLTTYLQTYFAEEIQRHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5G6</accession>
    <name>A0A2S9H5G6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Amino acid/peptide transporter (Peptide:H+ symporter)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_0417</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95222">
        <property type="protein sequence ID" value="PRC95222"/>
        <property type="gene ID" value="S2091_0417"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904680">
        <property type="term" value="F:peptide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006857">
        <property type="term" value="P:oligopeptide transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17346">
        <property type="entry name" value="MFS_DtpA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005279">
        <property type="entry name" value="Dipep/tripep_permease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000109">
        <property type="entry name" value="POT_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018456">
        <property type="entry name" value="PTR2_symporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11654">
        <property type="entry name" value="PTHR11654"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00854">
        <property type="entry name" value="PTR2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00924">
        <property type="entry name" value="yjdL_sub1_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01022">
        <property type="entry name" value="PTR2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0571">Peptide transport</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="33"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="63"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="93"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="116"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="155"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="184"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="236"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="278"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="312"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="344"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="379"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="410"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="444"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="482"/>
            <end position="500"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC95222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="512" mass="56046" checksum="EB85EA143C138B09" modified="2018-07-18" version="1">MNTQPSANPAQASVMGHPEGLFFLFFTEMWERFSYYGMRSLLVLFLISSTAKGGWGWERADALSLYGSYTFWVYVTGILGGYLADKVLGARKAVVIGGFIISAGHICLTLETHATFYLGLALLVAGTGLFKPNISTIVGQLYGKGEAEDEKRDAGYTLFYMGVNSGAFFGMALCGYIGEKISWSYGFGLAGFFMVLGALQFYFVQGVFGNIGGVVKDAPIAVAEVEEHAHIVRDRLIAIGIFSAVTIFFWMAFEQAGGSMTIFAADYTDRTLEGTTGMIFKVVNTLLLVIPTMVLTWVLFTLSRATVKRYPLSNFLIFTCFAAVWGLLIWMLGREFASDKSEIAATWFGILNSFFIIILAPFFSRLWQDYWKPSGPIKFATGLILLGIGFGVLAYGASGIPSGAKTASVSIIWLVLAYLFHTMGELCVSPVGLSYISKLAPSRLLGLMFGVWFVMTAIANYLAGMTGSFIDKISSTYSLSTFFLIFTLLPIGAGLGMMLINKWMLRKMHGVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5P7</accession>
    <name>A0A2S9H5P7_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Lipopolysaccharide export system permease protein LptF</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">S2091_0448</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95253">
        <property type="protein sequence ID" value="PRC95253"/>
        <property type="gene ID" value="S2091_0448"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030922">
        <property type="entry name" value="LptF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005495">
        <property type="entry name" value="LptG/LptF_permease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33529">
        <property type="entry name" value="PTHR33529"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03739">
        <property type="entry name" value="LptF_LptG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04407">
        <property type="entry name" value="LptF_YjgP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="52"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="266"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="300"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="332"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00014213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC95253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="383" mass="43114" checksum="9A1B9CA984ABAD6F" modified="2018-07-18" version="1">MIFKRALQRELASTAGAVFTILFTIAITVRPIKILGMAASGKVDSDDVFTLIGFAALNLLPIIIVLTGFISVLMVVTRSYQDSEMVVWFASGVSLTNWIVPILRFAAPLFVLTALMSFFVTPWANQHSVEYTDRFEQRSDIARVSPGKFQESASRERVFFVEGVAGDLSKVRNIFVNTIQNGRHSVVIAKEGEIVLDKFGDKFLIMHQGRRYDGAPNQTDFQMMQFDRYGVLVDSDTKALITEKKAEALSMSELWADQNPINMGELLWRISLPIMGVLLMVLAVPLGYVNPRSGRSANFLLALFLCVFYYNMVLVSQAWVKQSKFSLFLSWWPIHLACLLLITVLFVWRLNVNSRYHPLQIWAQLVRKKPACQVPQSAQGSAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSA6</accession>
    <name>A0A2S9GSA6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ankyrin repeats (3 copies)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4680</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000044">
        <property type="protein sequence ID" value="PRC90612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90612">
        <property type="protein sequence ID" value="PRC90612"/>
        <property type="gene ID" value="S2091_4680"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="SSF48403"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="36"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="69"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="125" mass="13730" checksum="FA1FB816EF6A0E45" modified="2018-07-18" version="1">MKNHANDKLENILRKYAALDMFEGYPINSPTSPGPDGDTPFHIAAYDGDIDGVKIMLPYVNDVNLKGDVGNTPLHYAISNRQLLMVEALISSGANVNLGNDYGDTPIDYMEGDEMFLPILAKLTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSA9</accession>
    <name>A0A2S9GSA9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Polysaccharide biosynthesis protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_4705</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000048">
        <property type="protein sequence ID" value="PRC90585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90585">
        <property type="protein sequence ID" value="PRC90585"/>
        <property type="gene ID" value="S2091_4705"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002797">
        <property type="entry name" value="Polysacc_synth"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01943">
        <property type="entry name" value="Polysacc_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="34"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="78"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="122"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="154"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="179"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="212"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="265"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="302"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="339"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="377"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="431"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="454"/>
            <end position="473"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC90585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="494" mass="55105" checksum="AB913C41AAEE5E96" modified="2018-07-18" version="1">MLIRNTFYNLLGLGLPLLVAIGSMPVLIHHLGDSRFGVLTLIWAVVSYFGLFDLGLGRALTQQLSLFIIEKRDHDIPSLIYTSFLLLLGLGIFAGLLMWLGAKWGANQMAYGGDVNEIIGSIHIMAIAMPFIVLTSGLRGILEAKLAFGVINLIRFPMGVFTFIGPLVVVLWYKNDLVSVTAVLTIGRIIACFAHGYYAVKKLPKMLSDRRYSPNLFRSLMVSGGWMTVSNIISPLMSYLDRFLISVTISAAAVAYYVTPNEMVTKIWIIPGALTAVLFPRFSAPIGDIANSEILTLFRSSVFYLVLIIAPITLMISYASQDILSLWLGYAFAEKSENLLKIFAYGVLLSSIAQIPFSLLQGNGKSFITARIHVAEFPVYCLMLWLGGTYFGLIGAGLIWLLRISVDTYLMFYCSFQIFDLKFKELLGMKFVILMLLITSSFLLSLVNDGILRLFLFIFSLILIAIYIWRIFLSVNEKLFFLKKIKNLTGNINA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSE5</accession>
    <name>A0A2S9GSE5_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">GDT1 family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_4666</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Membrane</location>
            <topology evidence="1 6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the GDT1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000042">
        <property type="protein sequence ID" value="PRC90630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90630">
        <property type="protein sequence ID" value="PRC90630"/>
        <property type="gene ID" value="S2091_4666"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001727">
        <property type="entry name" value="Gdt1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12608">
        <property type="entry name" value="PTHR12608"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01169">
        <property type="entry name" value="UPF0016"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="35"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="67"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="96"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="132"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="165"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU365102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC90630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="190" mass="20341" checksum="27B909EF40F3A6D1" modified="2018-07-18" version="1">MEAFLVSVVAITIGEIGDKTQLLALLLAARFKRPLPIVLGIFVATISNHILAALLGHWVATHLSADFLRWALGVSFLAIAAWTLKPDKMEESKIDYGKYGVFTITVITFFLAEIGDKTQIATMALAAKYDDIYMVLAGSTLGIMIADVPAVFLGKVASPNFPFKWIRWGAAAIFAVLGAAVLLGFGGGLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSH3</accession>
    <name>A0A2S9GSH3_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8 9">Chorismate synthase</fullName>
            <shortName evidence="8">CS</shortName>
            <ecNumber evidence="4 8 9">4.2.3.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">5-enolpyruvylshikimate-3-phosphate phospholyase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">aroC</name>
        <name evidence="10" type="ORF">S2091_4610</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8 9">
            <text>5-O-(1-carboxyvinyl)-3-phosphoshikimate = chorismate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:21020"/>
            <dbReference type="ChEBI" id="CHEBI:29748"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57701"/>
            <dbReference type="EC" id="4.2.3.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8 9">
            <name>FMNH2</name>
            <dbReference type="ChEBI" id="CHEBI:57618"/>
        </cofactor>
        <text evidence="8 9">Reduced FMN (FMNH(2)).</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 8 9">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 7/7.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8 9">Belongs to the chorismate synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.3.5" evidence="4 8 9"/>
    <dbReference type="EMBL" id="PUGF01000039">
        <property type="protein sequence ID" value="PRC90660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90660">
        <property type="protein sequence ID" value="PRC90660"/>
        <property type="gene ID" value="S2091_4610"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00053">
        <property type="reaction ID" value="UER00090"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004107">
        <property type="term" value="F:chorismate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:cellular amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009423">
        <property type="term" value="P:chorismate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd07304">
        <property type="entry name" value="Chorismate_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00300">
        <property type="entry name" value="Chorismate_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000453">
        <property type="entry name" value="Chorismate_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035904">
        <property type="entry name" value="Chorismate_synth_AroC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020541">
        <property type="entry name" value="Chorismate_synthase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21085">
        <property type="entry name" value="PTHR21085"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01264">
        <property type="entry name" value="Chorismate_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001456">
        <property type="entry name" value="Chorismate_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103263">
        <property type="entry name" value="SSF103263"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00033">
        <property type="entry name" value="aroC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00787">
        <property type="entry name" value="CHORISMATE_SYNTHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00788">
        <property type="entry name" value="CHORISMATE_SYNTHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00789">
        <property type="entry name" value="CHORISMATE_SYNTHASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8 9" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6 8 9" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0274">FAD</keyword>
    <keyword evidence="8" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-0288">FMN</keyword>
    <keyword evidence="7 8 9" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-0521">NADP</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="8">
        <location>
            <position position="48"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="54"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="125"/>
            <end position="127"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="240"/>
            <end position="241"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="280"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="295"/>
            <end position="299"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="321"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC90660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="367" mass="39260" checksum="C5F3AE91D07E5CE5" modified="2018-07-18" version="1">MSGNSFGSLFSVTTFGESHGPAIGCVIDGCPPGMVLSEADIQPELDRRKPGTSRHVTQRQESDKVEILSGVFEGKTTGTPIALLIRNEDQRSKDYGNIVDTFRPGHADYTYWHKYGIRDHRGGGRSSARLTAPAVGAGAIAKKWLREKYGTIIRGYMSQLGEIAIPFDDWQHVHANPFFAATDDPATIAKLEAYMDDLRKQGDSIGARINVVAQHVPVGLGEPIYDKLDAEIAYAMMGINAVKGVEIGAGFASIAQKGSEHGDELTPEGFIGNNSGGILGGISSGQDITVSIAIKPTSSIRTARNSIDQQGQAGVVQTFGRHDPCVGIRATPIAEAMLALVLMDHALRHRAQCGDVQVTTPNIAEKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSI3</accession>
    <name>A0A2S9GSI3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Membrane protease subunit stomatin/prohibitin-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_4620</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the band 7/mec-2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000039">
        <property type="protein sequence ID" value="PRC90670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90670">
        <property type="protein sequence ID" value="PRC90670"/>
        <property type="gene ID" value="S2091_4620"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001107">
        <property type="entry name" value="Band_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036013">
        <property type="entry name" value="Band_7/SPFH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032435">
        <property type="entry name" value="Band_7_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001972">
        <property type="entry name" value="Stomatin_HflK_HflKC_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01145">
        <property type="entry name" value="Band_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16200">
        <property type="entry name" value="Band_7_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00721">
        <property type="entry name" value="STOMATIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00244">
        <property type="entry name" value="PHB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117892">
        <property type="entry name" value="SSF117892"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="domain" description="PHB" evidence="3">
        <location>
            <begin position="22"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC90670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="306" mass="33334" checksum="D0E3DD074B0E7DBF" modified="2018-07-18" version="1">MEFNFGSVAFIMFVIAMVFVVKTINVVPQQHAWVVERLGKYHATLGPGLNIVLPFIDRIAYKHILKEIPLDVPPQVCITRDNTQLSVDGILYFQVTDAMRASYGSSNYIAAITQLAQTTLRSVIGKMELDKTFEERDHINTAIVNAIDESAANWGVKVLRYEIKDLTPPKEILHAMQAQITAEREKRALIAASEGRKQEQINIATGEREASIAKSEGEKQASINRAQGQAAAILSIAEASAEAIRKTAAAIQSPGGSDAVNLKVAEQYVSAFAQLAKTNNSIIIPANMGDISSLIATAMQVVKTQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSL6</accession>
    <name>A0A2S9GSL6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4588</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000038">
        <property type="protein sequence ID" value="PRC90695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90695">
        <property type="protein sequence ID" value="PRC90695"/>
        <property type="gene ID" value="S2091_4588"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="29"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="296" mass="33347" checksum="321FEF5CFBAF4EF2" modified="2018-07-18" version="1">MKTSTSEFIALRGHQYHCRHWGDPTAPMIFMVHGWMDVGASFQFVVDSLKADWHVIAPDMRGFGLTNGPTTDAYWFPDYLADLDALLQHYSPDAAINLVGHSMGGNVVGLYAGIRPERIAKLVILEGFGLPTTKPTQAPARYKKWLDELREKPEMRTYASAAEVAKRLQKTNPRLNDERAAFLAQHWSRENASGQWEILGDPAHKLSSPILYRVEEVMACWEAVTAPVLWVEADDTAIWSWIGGKEKGRPETDRRLTHFKQLKTELVLDAGHMLHHDQPQALAKLIEDFVGLPKAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSR5</accession>
    <name>A0A2S9GSR5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_4562</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000037">
        <property type="protein sequence ID" value="PRC90736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90736">
        <property type="protein sequence ID" value="PRC90736"/>
        <property type="gene ID" value="S2091_4562"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="11"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC90736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="321" mass="34811" checksum="43ADD1452DD14578" modified="2018-07-18" version="1">MKTTLSARDVLTPDALAMLQGIADTGSFAAAARALGMVPSALTYRVRQIEDALDVLLFDRSSRQAQFTVAGSELLREGARLLADVDAIANRVKRVATGWEPTFTIAIDSIIHRTVILELCEAFFGLNPPTRVRLRAETLSGTLESLTSGQADLAIGVTDEAANSAGFQVRPLGDSRFVYAVAPHHPLAHETEPLSDELIRQHRAVAVADSVQRGGGLTLGLLGGQDVFTVPNMQAKLEAQLRGIGSGFLPEFLAEPYIKTGRLVEKRVERVERVVRVSYAWRKTPGTSRGNAMKWWLEQLDSAKTRNALLGGIPVGFLDVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSV6</accession>
    <name>A0A2S9GSV6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4541</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000036">
        <property type="protein sequence ID" value="PRC90793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90793">
        <property type="protein sequence ID" value="PRC90793"/>
        <property type="gene ID" value="S2091_4541"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="60"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="425" mass="48027" checksum="84EBABAF476F395A" modified="2018-07-18" version="1">MQKIPYIAAAVIGLLLSAYSLIFAMLSGPQFAWIIGCSLLLAHILAAIIAIKKATNNKMVFAIVTLISPVFIVFIGAMLFLYAESLENRYLPDKNFVKICEDSELKYFRSPKLKVSSIHLDWAPMSGSIMSKYIIDSDHMFEDVEDNLIVPDMISDSTLSDVLVTHEISNPDELNQAIVNRGLIQYTLTVTDRRDGSKLATMKYAVDHSKKRACGNNTSNAIDLNAFITNATALSDVGNSVLISSKMQQNSTLDKEKNISDNPISVDFEVLETEKYSRRRVVTNGEIDLFFKEQEQICDSLLKPYRLGTPWMTFKKDPSGLKKIDFYTGFKFCGSNAVWMGDYVYKGDSKHFVLTKYADNGDFNYRIRILRPNNPIFDTASLDETTFHAADGVITFDWINFDRDSGVIRISQRMKIQIKEPIKRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GT25</accession>
    <name>A0A2S9GT25_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Serine--tRNA ligase</fullName>
            <ecNumber evidence="8">6.1.1.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Seryl-tRNA synthetase</fullName>
            <shortName evidence="8">SerRS</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Seryl-tRNA(Ser/Sec) synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">serS</name>
        <name evidence="10" type="ORF">S2091_4427</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>ATP + L-serine + tRNA(Sec) = AMP + diphosphate + H(+) + L-seryl-tRNA(Sec)</text>
            <dbReference type="Rhea" id="RHEA:42580"/>
            <dbReference type="Rhea" id="RHEA-COMP:9742"/>
            <dbReference type="Rhea" id="RHEA-COMP:10128"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78533"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.11"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>ATP + L-serine + tRNA(Ser) = AMP + diphosphate + H(+) + L-seryl-tRNA(Ser)</text>
            <dbReference type="Rhea" id="RHEA:12292"/>
            <dbReference type="Rhea" id="RHEA-COMP:9669"/>
            <dbReference type="Rhea" id="RHEA-COMP:9703"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78533"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.11"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="8">Aminoacyl-tRNA biosynthesis; selenocysteinyl-tRNA(Sec) biosynthesis; L-seryl-tRNA(Sec) from L-serine and tRNA(Sec): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer. The tRNA molecule binds across the dimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="8">Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.11" evidence="8"/>
    <dbReference type="EMBL" id="PUGF01000034">
        <property type="protein sequence ID" value="PRC90846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90846">
        <property type="protein sequence ID" value="PRC90846"/>
        <property type="gene ID" value="S2091_4427"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00906">
        <property type="reaction ID" value="UER00895"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004828">
        <property type="term" value="F:serine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016260">
        <property type="term" value="P:selenocysteine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097056">
        <property type="term" value="P:selenocysteinyl-tRNA(Sec) biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006434">
        <property type="term" value="P:seryl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00770">
        <property type="entry name" value="SerRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00176">
        <property type="entry name" value="Ser_tRNA_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002314">
        <property type="entry name" value="aa-tRNA-synt_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002317">
        <property type="entry name" value="Ser-tRNA-ligase_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015866">
        <property type="entry name" value="Ser-tRNA-synth_1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042103">
        <property type="entry name" value="SerRS_1_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033729">
        <property type="entry name" value="SerRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010978">
        <property type="entry name" value="tRNA-bd_arm"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43697">
        <property type="entry name" value="PTHR43697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02403">
        <property type="entry name" value="Seryl_tRNA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00587">
        <property type="entry name" value="tRNA-synt_2b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001529">
        <property type="entry name" value="Ser-tRNA-synth_IIa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00981">
        <property type="entry name" value="TRNASYNTHSER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46589">
        <property type="entry name" value="SSF46589"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00414">
        <property type="entry name" value="serS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 8 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="9">
        <location>
            <begin position="170"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="region of interest" description="Serine binding" evidence="8">
        <location>
            <begin position="237"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="268"/>
            <end position="270"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="291"/>
        </location>
        <ligand>
            <name>L-serine</name>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="355"/>
            <end position="358"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="390"/>
        </location>
        <ligand>
            <name>L-serine</name>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC90846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="434" mass="47905" checksum="A10163BC6D2640E6" modified="2018-07-18" version="1">MIDIQLLRKDISTVAERLAQRKFSLDVDGFNALEAQRKQCQSRSEELQGLRNSLSKQIGMLKGKGEDASALMEQVNGIADELKSSATRLEQIQVELTNFAEGIPNLPHPTTPIGASEENNVEVRRFGTPRQFDFEVRDHVDVGASLGLDFDTAVKLTGSRFTLLKGGIARLHRALAQFMLDTHTMEHGYTECYTPYIVNAASMRGTGQLPKFADGLFSVKKGGQEGGEEETLYLIPTSEVSLTNIVRDEIVPLASLPMKFTAHTPCFRSEAGSYGRDTRGMIRQHQFDKVELVQIVHPDESDATLEQMVLQAEVILQKLDLPYQVMALCTGDMGFSAAKTYDINVWLPAQNTYREISSLSNMEAFQARRMQARFRNAQGKPELLHTLNGSGLAVGRTLVAILENHQQADGSVNIPAVLHPYMGGVISLKPEGAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GT49</accession>
    <name>A0A2S9GT49_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Calcineurin-like phosphoesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4395</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000033">
        <property type="protein sequence ID" value="PRC90902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90902">
        <property type="protein sequence ID" value="PRC90902"/>
        <property type="gene ID" value="S2091_4395"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003993">
        <property type="term" value="F:acid phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP_ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039331">
        <property type="entry name" value="PPA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22953">
        <property type="entry name" value="PTHR22953"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallophos" evidence="1">
        <location>
            <begin position="140"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="480" mass="51220" checksum="18537659198C30AD" modified="2018-07-18" version="1">MLESAISSTIAMAISTFPILLFLSACSTVSLTKSTNAAQVQADAAQIQAAWVVIGEQGQAVARVITRAAVCPVMQQDDTELPMQVRAASGTVAQRTTLSSTADSKPSEFPVLTCEAQLKSGVISASVAGKPLPVPKPVPLKILVVGDSGCRMKLADNAFQSCNDVDKWAFSTVAKTAAGFAPDLVIHVGDYQYRENPCPAGNATCAGSPWGFGWDTWQADFFTPAAPLLAAAPWVMARGNHESCARAGQGWWRFMDPRALQQGRDCNVENDDMQGDYSAPYAVPLGAGAQLIVFDSSKTSAKPLAKTDSAYSIYSAQFKAVDHLAEQAEFSIFLEHHPILGFAPEKKNTSGVEVKPGNLALQSVLQDQHPQRLFAPNVQLLLAGHVHLFEAITFDTDHPMQLVSGNGGSSPDVDLPAKLSPQATPFVNAKVAHFNSTSQSGFMTMERASVTATDWVVKAWDKNGVLMTTCSVSKLKKECS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GT50</accession>
    <name>A0A2S9GT50_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">P2-like prophage tail protein X</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4449</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000034">
        <property type="protein sequence ID" value="PRC90868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90868">
        <property type="protein sequence ID" value="PRC90868"/>
        <property type="gene ID" value="S2091_4449"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008861">
        <property type="entry name" value="GpX-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05489">
        <property type="entry name" value="Phage_tail_X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC90868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="70" mass="7653" checksum="3FDCBFE450B85A6C" modified="2018-07-18" version="1">MSITVRTQQYDTLDLVCWRHLGTTNGVVEAALELNRTIADPGAILPHGTLVTLPEPSAMTPTSHVVQLWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTD7</accession>
    <name>A0A2S9GTD7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_4367</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000032">
        <property type="protein sequence ID" value="PRC90966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90966">
        <property type="protein sequence ID" value="PRC90966"/>
        <property type="gene ID" value="S2091_4367"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="2">
        <location>
            <begin position="70"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="214"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC90966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="393" mass="43706" checksum="35AF450A8A9DE472" modified="2018-07-18" version="1">MKLLTFSTLYPNAEQANHGIFVETRLRYLVASGQAESRVIAPIPWFPSKHPHFGRYASFARVPEAETRQGIHIDHPRYTQIPKIGMHLSPLLMAHSLKKTLARIIDEGYDFDLIDAHYFYPDGVAAVMLGKYFNKPVVITARGTDINLIPQYHLPKKMILWAAKNARGVITVCHALKDEMVKLGVPSEHITPLRNGVDLQRFQPMDRQKVRQELGLQHFTLLSVGSLTTHKGHDLVIRALSSLTDIHLMIAGSGPEHQKLHELAQQLGVADRVQWLGSVPQTELKTFYSAADALVLVSSREGWANVLLESMACGTPVIASNVGGSPEVVTSLDAGILISERTPQALIAAIHSLRANYPEHEATRRYAEKFSWDETTQGQLRLFNTILNGGKAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTK3</accession>
    <name>A0A2S9GTK3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4235</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000030">
        <property type="protein sequence ID" value="PRC91047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91047">
        <property type="protein sequence ID" value="PRC91047"/>
        <property type="gene ID" value="S2091_4235"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010281">
        <property type="entry name" value="DUF885"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33361">
        <property type="entry name" value="PTHR33361"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05960">
        <property type="entry name" value="DUF885"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015605187" evidence="1">
        <location>
            <begin position="22"/>
            <end position="597"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="597" mass="66506" checksum="E31408F1E30F6BA7" modified="2018-07-18" version="1">MFQSKLFLATCLMGFVTCVSAAQETQTHVQLVQLAQDMTQTTAKLYPISATMMGITGHDGELEQPSEAYRQHYIGQMNLWQKQLKTIVAGAGKTMSLVDQDDAKLLQSKIARELNQLTIYRQDRKDYGSWALNIVGVIYDQFLHLPVNGVEGASNADVTSAWNDIIARMSKASDYIVRGQRLSTTPGHLFGVISSEQLGGAPEFLNEALTGAAKSQLGEQSAEYRRFVQARDQVLQTLSVTKSYIDAHLKSWPENHTITPETYDMMLRDEQLLPFKSVDVQRMGWDELSHGWAEEAWLKSRSVKSGLPFGPLSGGGIAPDGAALIDYYRDRIADLRKFVVDNDVVTVPAWLGSMKIIETPSFLQSVSPGASMNSPRLFSTSTTGFYFITPPKSLKEAAERLDMNQDFDSDRIMSTAAHEAMPGHFMQLSIAKRHSNYIRRIQESGVFAEGWAFYGEEMFVRLGMYGDNLDGRLFTARWERVRGARAIVDYKFITGEWSYELAAEFYSKQSGFTLDAAKAAVAGIAKNPGYMIAYTVGRLQLQTLLGEYMLRTGANGSLHDFHDRLLSYGTTPFAVVGPELLQDLNKPVQEVRAAANY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTP0</accession>
    <name>A0A2S9GTP0_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Enoyl-[acyl-carrier-protein] reductase [NADH]</fullName>
            <ecNumber evidence="6">1.3.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">S2091_4176</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>a 2,3-saturated acyl-[ACP] + NAD(+) = a (2E)-enoyl-[ACP] + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:10240"/>
            <dbReference type="Rhea" id="RHEA-COMP:9925"/>
            <dbReference type="Rhea" id="RHEA-COMP:9926"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:78784"/>
            <dbReference type="ChEBI" id="CHEBI:78785"/>
            <dbReference type="EC" id="1.3.1.9"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.9" evidence="6"/>
    <dbReference type="EMBL" id="PUGF01000029">
        <property type="protein sequence ID" value="PRC91080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91080">
        <property type="protein sequence ID" value="PRC91080"/>
        <property type="gene ID" value="S2091_4176"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00094"/>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004318">
        <property type="term" value="F:enoyl-[acyl-carrier-protein] reductase (NADH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016631">
        <property type="term" value="F:enoyl-[acyl-carrier-protein] reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd05372">
        <property type="entry name" value="ENR_SDR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014358">
        <property type="entry name" value="Enoyl-ACP_Rdtase_NADH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43159">
        <property type="entry name" value="PTHR43159"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000094">
        <property type="entry name" value="Enoyl-ACP_rdct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="5 6" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="6" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="5 6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="4 6 9" id="KW-0520">NAD</keyword>
    <keyword evidence="3 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="146"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="156"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="13"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="19"/>
            <end position="20"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="64"/>
            <end position="65"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="92"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="95"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="163"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="192"/>
            <end position="196"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR000094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000094-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000094-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000094-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC91080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="259" mass="27581" checksum="01D786274E107F36" modified="2018-07-18" version="1">MAFLQGKKILITGLLSNRSIAYGIAQACKREGAELAFTYVGERFKDRITDFAAEFDSKLIFDCDVGSDEQIDAVFADLSKSWDKLDGLVHAIGFAPREAIAGDFLEGLSRESFKIAHDISAYSFPALAKAAQSMLSDEAALITLTYLGAERAIPNYNTMGLAKASLEASVRYLAETMGKDGVRVNGISAGPIKTLAAAGIKDFSKLLGLAAQMAPLRRNVTIHDVGNTAAFLLSSLSSGITGEIIYVDGGFSHVAVNVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTR6</accession>
    <name>A0A2S9GTR6_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_4197</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="PUGF01000029">
        <property type="protein sequence ID" value="PRC91101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91101">
        <property type="protein sequence ID" value="PRC91101"/>
        <property type="gene ID" value="S2091_4197"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="6">
        <location>
            <begin position="6"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="5">
        <location>
            <begin position="162"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="4">
        <location>
            <position position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC91101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="402" mass="44939" checksum="4C281A1195FFA0C6" modified="2018-07-18" version="1">MGELFKILAVDDNQGNRFLLNELLARLPDVEVIEASSGAEALLRTVEHDFQLILLDVHMPIMDGYETARLLQMTSRTRNIPIVFLTAVFKSEEFIKRGYALGAVDYLTKPLDDNIFLNRVRHYQHLQDRENRLITALSEMRSMQDNLLQSEKLSALGAMVAGVSHELNTPLGNSKLAISTMHDRLNELNRHYLAGTIKRSNIEEFIKESLDIVVLANRSIERALNLVVTFKQVAVDQTSEQRRLFDLATVINETITSLRPSFKHDPWQFDIEIPAGIQMDSYPGPLEQIIINLVHNSIRHGFDGRGHGCITIRASTEENDLSQKLVTIVFKDDGNGIAPNNIGRVFDPFFTTRLGRGGSGIGLNITHRIATSLLAGSIHVESEFGFGATFTLTVPCKVHSAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTU3</accession>
    <name>A0A2S9GTU3_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">UPF0301 protein S2091_4209</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_4209</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the UPF0301 (AlgH) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000029">
        <property type="protein sequence ID" value="PRC91113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91113">
        <property type="protein sequence ID" value="PRC91113"/>
        <property type="gene ID" value="S2091_4209"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00758">
        <property type="entry name" value="UPF0301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003774">
        <property type="entry name" value="UPF0301"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30327">
        <property type="entry name" value="PTHR30327"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02622">
        <property type="entry name" value="DUF179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00758"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="218" mass="23784" checksum="DE857137996C0F2C" modified="2018-07-18" version="1">MTEHIKPYQISTESGSKPGSSFHVDFMPLSDLNLANHFLIAMPSMQDPMFGGTVIYLCEHNDRGALGVVINKPTDMNIETLLERISIKLDITPELCQETKKLVMFGGPVQDDRGFVLHAPLDDYTSTIKISDQIAFTTSRDVLEAVANGSGPKRLLVSVGYAGWSAGQLEDEIIRNGWLTVPADPAILFDMPIELRFSAALKLLGIDPIMLSGEAGHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTV3</accession>
    <name>A0A2S9GTV3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Enoyl-CoA hydratase/carnithine racemase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4139</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the enoyl-CoA hydratase/isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000028">
        <property type="protein sequence ID" value="PRC91138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91138">
        <property type="protein sequence ID" value="PRC91138"/>
        <property type="gene ID" value="S2091_4139"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018376">
        <property type="entry name" value="Enoyl-CoA_hyd/isom_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00166">
        <property type="entry name" value="ENOYL_COA_HYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="261" mass="28059" checksum="3328C7B8D62BD84D" modified="2018-07-18" version="1">MTEEVLIVETIGSVARITLNRPRAMNSLNFAILAELERNLINIAANDELRAVILTGAGTAFCAGADLKEVLQGKQNKPGEADFLDRANQVFGLLRNFPKPVIAALNGVTMAGGLELAMCADVIVAASSATIADAHANFGVYPGAGGAAVLSRLIPLNMAMYLLLTGKSLTATEMHNCGLVCEVHADDELADATLKLAAHIAKKSPIALFRMKQVARASADKSREDALLHEQVMLRQHMRSFDFQEGLQSFMEKRAPNFQGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUA6</accession>
    <name>A0A2S9GUA6_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transcription elongation factor GreB</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Transcript cleavage factor GreB</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">greB</name>
        <name evidence="7" type="ORF">S2091_3961</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the GreA/GreB family. GreB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000025">
        <property type="protein sequence ID" value="PRC91290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91290">
        <property type="protein sequence ID" value="PRC91290"/>
        <property type="gene ID" value="S2091_3961"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070063">
        <property type="term" value="F:RNA polymerase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032784">
        <property type="term" value="P:regulation of DNA-templated transcription, elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00105">
        <property type="entry name" value="GreA_GreB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00930">
        <property type="entry name" value="GreB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036953">
        <property type="entry name" value="GreA/GreB_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028624">
        <property type="entry name" value="Tscrpt_elong_fac_GreA/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001437">
        <property type="entry name" value="Tscrpt_elong_fac_GreA/B_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023459">
        <property type="entry name" value="Tscrpt_elong_fac_GreA/B_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022691">
        <property type="entry name" value="Tscrpt_elong_fac_GreA/B_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036805">
        <property type="entry name" value="Tscrpt_elong_fac_GreA/B_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006358">
        <property type="entry name" value="Tscrpt_elong_fac_GreB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30437">
        <property type="entry name" value="PTHR30437"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01272">
        <property type="entry name" value="GreA_GreB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03449">
        <property type="entry name" value="GreA_GreB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006092">
        <property type="entry name" value="GreA_GreB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46557">
        <property type="entry name" value="SSF46557"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01461">
        <property type="entry name" value="greB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0804">Transcription</keyword>
    <keyword evidence="1 4" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="GreA_GreB_N" evidence="6">
        <location>
            <begin position="27"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="domain" description="GreA_GreB" evidence="5">
        <location>
            <begin position="106"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC91290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="181" mass="20362" checksum="E9BCE308927F42F3" modified="2018-07-18" version="1">MNNNQSNQDDDEEQTSALLQISPGAKNYITMPGYLAMKDEFLQLMDVARPEMVKIVSWAASNGDRSENGDYIYGKRRLREIDRRIRFLTKRIDLAEVVDPRVHHGSDQVFFGATVKYETQAGVEHEVTIVGVDEFDPLRGKISWVSPIARALNKAHEGDTIVLQTPAGLEEITLLEVSYPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUB4</accession>
    <name>A0A2S9GUB4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, Spx/MgsR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3996</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the ArsC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000025">
        <property type="protein sequence ID" value="PRC91325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91325">
        <property type="protein sequence ID" value="PRC91325"/>
        <property type="gene ID" value="S2091_3996"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006660">
        <property type="entry name" value="Arsenate_reductase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006504">
        <property type="entry name" value="Tscrpt_reg_Spx/MgsR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30041">
        <property type="entry name" value="PTHR30041"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03960">
        <property type="entry name" value="ArsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01617">
        <property type="entry name" value="arsC_related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51353">
        <property type="entry name" value="ARSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="123" mass="14160" checksum="93FB60933505761B" modified="2018-07-18" version="1">MNVTLYGIPNCDQVKKARTWLSEHQVTVDFHDFKKAGVTPALISPWLKQLDWQILLNRRGTTWRKLPEAEQQAVIDADSAVQCMVNSPSVIKRPVLVIQTDMQVEIMVGFSEAEYRRWFTTQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUE9</accession>
    <name>A0A2S9GUE9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_4010</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000025">
        <property type="protein sequence ID" value="PRC91339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91339">
        <property type="protein sequence ID" value="PRC91339"/>
        <property type="gene ID" value="S2091_4010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="129"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="385"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="458"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="536"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="609"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="769"/>
            <end position="818"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="850"/>
            <end position="996"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1075"/>
            <end position="1123"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1213"/>
            <end position="1243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="1331" mass="150912" checksum="B2C0E516FD2DA5CA" modified="2018-07-18" version="1">MDIEHSQQQNQDDEHIGGMGSHERVMDLKSIRAAIARVEAEARATVAAENRAFVEARARAVAEDRAELDNQALLEAEQTLQLEEQAKIASKSRWQAEQQARLAQQIRIAASQKEIQAIEARVQMDAQAAQASKERLQVEQYAREQAEEQINLEKSLSERAKQAGEQYKNQAAIAREQCVLLSETETAAKQEAAARAQSEAKLVELARTEQKIENSAKIRAEALVESQEKMLAIRAERELVQVAALHLSMQNTSTEVWALEQAKAHASVLKEQLSIFEARSETEQAATHALETRLKAEHELQQAAERRLYTESMAATTAQARRSAEQKLQFIAEQRIATEKALQDQAWQQVEQQQKAEQAAQLRLQHEAEVIQQAALREQADQDALHLLQQSLQSEQQAKKSAEQRLQLAQQAADAALAQQLSEQAQQAAQAEHTRLQRENSYLHAQEAEQARQLVIVERQHLQALQTARQLLEQQKENKQQLLKQEEQQAATLQAQNGVLKMQEQAALAAQQISATSYRAGKLLLQQNVHYSELKRQEAENLIEKGRQTLELVQLQQQRVEQEQQTLQLLQKKGLLEQKRAQSAAEVAAATQEKIDQEQRSFVLNQEQCLAEQEQKQALEQQCAEQQKIILAKQAQVKAEQHQLAQLQVQREAQRQAALAALEQAKQSVNLSQAKLRHAQLEQEAARAMHEKCQAEQALCEQTQQRKAAELVQTGVLQQLTEQELAAQNAIHEATRLTSERLIAANAQTALRQQVLSVAEAKQQIAADLLGQEQKNYELEQQAQLAEQQKLETQRAHHQQLQQRLVEEQKSRDLHQQNLQQEQAATQAASLISQQKTALLQQTTQLSLSRQAVQQLLATKEQTAKKLAEEVQERNQSEQLLLQKMVDARELIEQRIAKNRHLEKAQQQRVQEEQHAIQLLEERLQTEQELTKLHQQRSLAEQEAKDLLESSYAEQQARLTQIEKLARINARLTQRAQQLEQKHSTELQAIKTLQQQKVRDQQAAVLALQQQRLAEQESVKAVAEQTVQQKNQAQLARQQCQHELEARQAFEAECAAQQAITEQSKLQAEAALQCQAEKQQRLQEMQHLVELEQRKTSLEQQMRDDLSVKLAALQRQISIAKTRAELEHRQAHCNVQRTQVEQQALQLLQVQHQEHEAFLANEKQKMLHLAKGVELAREKTRLEQEAAKKAESDTQQQQHSLELMMQKLDQQSHKSQQRELAAQQKLEREIEAEMTQATQLSAQLFERLSCQQSGSKEWVRRARLVLQEAPSPLRPVAKSPYRRMAGVIVGVVALIGVSSATFLPPAAAPGLVAHAAVADLKMSYSLADKRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUK1</accession>
    <name>A0A2S9GUK1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Negative regulator of beta-lactamase expression</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3923</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000024">
        <property type="protein sequence ID" value="PRC91378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91378">
        <property type="protein sequence ID" value="PRC91378"/>
        <property type="gene ID" value="S2091_3923"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008745">
        <property type="term" value="F:N-acetylmuramoyl-L-alanine amidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009253">
        <property type="term" value="P:peptidoglycan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06583">
        <property type="entry name" value="PGRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.80.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036505">
        <property type="entry name" value="Amidase/PGRP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002502">
        <property type="entry name" value="Amidase_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01510">
        <property type="entry name" value="Amidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00644">
        <property type="entry name" value="Ami_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55846">
        <property type="entry name" value="SSF55846"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetylmuramoyl-L-alanine amidase" evidence="1">
        <location>
            <begin position="25"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="209" mass="23415" checksum="9405FAAC9875BEE7" modified="2018-07-18" version="1">MSNPLSLPLIAMQDGWASQAEQQASPNFDARPTACAPELLVIHAISLPLGQFSEAGAQAFYIADLFLNQLDYSAHPDFEQLKGVRVSAHFLIRRDGSLVQFVSTDQRAWHAGLSDFMGRTRCNDFSIGIELEGSDFVPFEAAQYVTLTRLTATLVQHYPIQHIVGHQDIAPARKTDPGPFFNWQQYQDLLHQHFPLVLTNAAIRFHADR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUS3</accession>
    <name>A0A2S9GUS3_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Common pilus major fimbrillin subunit EcpA</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">MatB fimbrillin</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_3863</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="5">Self-associates. Forms filaments. Interacts with EcpD.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Fimbrium</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the EcpA/MatB fimbrillin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000023">
        <property type="protein sequence ID" value="PRC91448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91448">
        <property type="protein sequence ID" value="PRC91448"/>
        <property type="gene ID" value="S2091_3863"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009289">
        <property type="term" value="C:pilus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.3290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016514">
        <property type="entry name" value="EcpA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038478">
        <property type="entry name" value="Fimbrillin_EcpA_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16449">
        <property type="entry name" value="MatB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0281">Fimbrium</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015584427" description="Common pilus major fimbrillin subunit EcpA" evidence="7">
        <location>
            <begin position="23"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00014507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00026091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00031192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC91448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="226" mass="23538" checksum="CB438C9D76956ACA" modified="2018-07-18" version="1">MKNLVKLSVLGVLVAASFSASASGEVTTANTSVKWNAEAVKKSDVELNVFASNDALQFKWDVTNKRFSNASSSLTIQAAGKPNSTAYSITSQLLRKKLTHLSGAGTGTLSLGATLGGLAMTDKPVSILAGNDFDMTASAAGMQAMNLSKAGPNTTPKGSYHEANNVMVDFRIEEGTDSAGKELTLGSDDKGLDMLADGVYEGQVELAFVASWTAGYSSKPSEPDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUY4</accession>
    <name>A0A2S9GUY4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3815</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000022">
        <property type="protein sequence ID" value="PRC91537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91537">
        <property type="protein sequence ID" value="PRC91537"/>
        <property type="gene ID" value="S2091_3815"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="7"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="306" mass="33674" checksum="C766457F7B4419CE" modified="2018-07-18" version="1">MAAFPHITLEQWRALITVVDTGSYANAAEALHKSQSSVTYAVQKLESLLGISAFEIQGRKAVLTPTGQLLYRRALHLLAEAENIERAAKKISAGWEPEIRLAADIIFPSFILLDCFDQFGKKSPHTRIELIESVMGGTIEALLTGQVDLAIATSIPQGFLGRTLIQLRFIPVAHPNHPLHQLNRELSIRDLETERHLVIRESGSKRTTNTLIAQAPQRWTVGHSATSIEAVARGYGFAWFPEVNIRHQLKEGTLKALPLKDGGERFATMYLIFADPDVAGPGTQYLAQLIQDAVLSTCAEHVANKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUY5</accession>
    <name>A0A2S9GUY5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ABC-type cobalamin/Fe3+-siderophore transport systems ATPase component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_3801</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000022">
        <property type="protein sequence ID" value="PRC91523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91523">
        <property type="protein sequence ID" value="PRC91523"/>
        <property type="gene ID" value="S2091_3801"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-1278">Translocase</keyword>
    <feature type="domain" description="ABC transporter" evidence="7">
        <location>
            <begin position="3"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="35"/>
            <end position="42"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC91523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="266" mass="29348" checksum="2F67A2510078F61F" modified="2018-07-18" version="1">MKLQTKNLTLSVGKRSLVANLNWQVNAGECWCIIGRNGAGKTTLLRCLAGLFDVAANAGEVLINDRSLAKWPLTELAKVRSYLPQGRNDAFAYRVIESVLGARHPYHDGHYWESDQDLAAAYAALTELDVADLAERDVRSLSGGERQRVAIASLLAQDAQLMLLDEPTNALDLAHQISVMQTFSQRCKNQQKALLMVSHDLNLAYSIATHALLLMGDGSWQAGTVLEIMTEANLSQCLGHPIEMIWHGKQRLFLPVQAQLLAQTFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GV49</accession>
    <name>A0A2S9GV49_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3713</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000021">
        <property type="protein sequence ID" value="PRC91597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91597">
        <property type="protein sequence ID" value="PRC91597"/>
        <property type="gene ID" value="S2091_3713"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="410" mass="46154" checksum="B5F9DCDDFE4D4241" modified="2018-07-18" version="1">MSDTDSDFQVATFEDRPFFEKALRYGFQQGIINNEKISAIAIEAPKGMVQIAAAFGSQYLRPEIDTARLRIVNLASLYLIETAKGDLELAAKLIRDNTFLSLSRGGSNLLKALFAMPEYAILGMDEKGRIEDFLEFWSRKKTGPDYQAAVQQRQTNQVEINLALKLGKALGLSAHDFHDQHSEAEAIIRSALLISLQKKVIVNIRCFNQVEFANMLNLTRSKGIAKAAKLSIELSQQLSTAEQAIITRLQHDILTNDIPKILDTEISLDKLINQLKDRFFIRDHDMEDSASYDALVSKEWSKHTKGKTDIDAILTMLLCIAAATPAKTSLSEKAAKTLVKKIRSEGFQPELASDFIKQHAPHEKQASLLDDWTDFSLEAQTYLLDDWDTNLYGAMRFLQENCYVEKSVKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVC4</accession>
    <name>A0A2S9GVC4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">CBS domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3602</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000020">
        <property type="protein sequence ID" value="PRC91664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91664">
        <property type="protein sequence ID" value="PRC91664"/>
        <property type="gene ID" value="S2091_3602"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0129">CBS domain</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBS" evidence="2">
        <location>
            <begin position="8"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="2">
        <location>
            <begin position="75"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="150" mass="16866" checksum="2DAFF6232E0DC7BF" modified="2018-07-18" version="1">MKVSEILQVKGDILYTVTPDESMVNAVNIMEEKDIGSLVVMEFGEVAGMLSFREVIKAIHSNGGSLGAGTVRKYMDDHPLTVTPDTEVNEVRRVMLEKHARYLPVMNAKMLLGVISFYDVAKAVLEAQSFENKMLKAYIRDWPAEQEQEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVK1</accession>
    <name>A0A2S9GVK1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Proton-translocating NADH-quinone oxidoreductase, chain M</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_3624</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 3">Membrane</location>
            <topology evidence="1 3">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the complex I subunit 4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000020">
        <property type="protein sequence ID" value="PRC91686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91686">
        <property type="protein sequence ID" value="PRC91686"/>
        <property type="gene ID" value="S2091_3624"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008137">
        <property type="term" value="F:NADH dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042773">
        <property type="term" value="P:ATP synthesis coupled electron transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000260">
        <property type="entry name" value="NADH4_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010227">
        <property type="entry name" value="NADH_Q_OxRdtase_chainM/4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003918">
        <property type="entry name" value="NADH_UbQ_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001750">
        <property type="entry name" value="ND/Mrp_mem"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43507">
        <property type="entry name" value="PTHR43507"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01059">
        <property type="entry name" value="Oxidored_q5_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00361">
        <property type="entry name" value="Proton_antipo_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01437">
        <property type="entry name" value="NUOXDRDTASE4"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01972">
        <property type="entry name" value="NDH_I_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="34"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="87"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="114"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="138"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="170"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="210"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="242"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="274"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="304"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="335"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="374"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="407"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="449"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="domain" description="Oxidored_q5_N" evidence="6">
        <location>
            <begin position="66"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="domain" description="Proton_antipo_M" evidence="5">
        <location>
            <begin position="136"/>
            <end position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC91686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="494" mass="54282" checksum="1F3055C2CC9BD8C8" modified="2018-07-18" version="1">MMQSTSILLSLAIWLPIAFGIFVIAFGKDENPNLVRIVSLIGAVTSFLVTLPLIKEFDNAAHGMQFVEHSSWIERFNVNYYLGIDGISLWMVILTAFISVIVVIAGWVVIEKRVAQYMGAFLILSGLMIGVFCALDGLLFYVFFEATLIPMYIIIGVWGGANRVYASFKFFLYTLMGSLLTLIAIIYLYTQSGSFDILVWHKLPLNLNQQILIFCAFLMAFAVKVPMWPVHTWLPDAHVEAPTGGSVVLAAIMLKLGAYGFLRFSLPIAPDASHYLSGFIITLSLIAVIYIGLVALVQTDMKKLVAYSSIAHMGFVTLGFFMFNDMSVQGGLVQMISHGFISGAMFLCIGVLYDRVHSRQIVDYGGVVNTMPKFAAFFVLFSMANCGLPATSGFVGEFMVIMGAVKFNFWIGMLAATALIFGAAYSLWMVKRVVFGAVTHKHVAELTDLSAREFFMLAVLAIAVLAMGLYPQPFTAAMQTTVTDLLAHVATSKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVL4</accession>
    <name>A0A2S9GVL4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Thioesterase superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3509</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000019">
        <property type="protein sequence ID" value="PRC91754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91754">
        <property type="protein sequence ID" value="PRC91754"/>
        <property type="gene ID" value="S2091_3509"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006683">
        <property type="entry name" value="Thioestr_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03061">
        <property type="entry name" value="4HBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4HBT" evidence="1">
        <location>
            <begin position="18"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="143" mass="16199" checksum="469FD6C3B05F4FE0" modified="2018-07-18" version="1">MKFTLPIQIRFAHCDPAGIVFYPRYFEFFNTVIEDWCEHGLGSSFREMHMQLGYGLPTAHVECSFLKPSELGEILQAQLSLTKVGNTSLHVEIALLGPDAVQRVLAKMVLVLMDMKTRKAISLPVSLRQKMMPYLKEVLGTEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVM8</accession>
    <name>A0A2S9GVM8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3534</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000019">
        <property type="protein sequence ID" value="PRC91779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91779">
        <property type="protein sequence ID" value="PRC91779"/>
        <property type="gene ID" value="S2091_3534"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000551">
        <property type="entry name" value="MerR-type_HTH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13411">
        <property type="entry name" value="MerR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00040">
        <property type="entry name" value="HTHMERR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00422">
        <property type="entry name" value="HTH_MERR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50937">
        <property type="entry name" value="HTH_MERR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH merR-type" evidence="2">
        <location>
            <begin position="5"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="79"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="152" mass="17029" checksum="948803520919CE06" modified="2018-07-18" version="1">MHKCNYTIGQLSKVAEVGIETIRYYQRRQLLSIPAASSGAVRIYSSQFVERLRFIKGAKELGFTLDEVASLLQLNDQESDQGSEVTSQKHLKQTSRSSVRQLASDKLTQVRKKMDDLQKIEHILVRLISECADTDSSLPCPIVEAITCKIAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVN9</accession>
    <name>A0A2S9GVN9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major Facilitator Superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_3544</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000019">
        <property type="protein sequence ID" value="PRC91789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91789">
        <property type="protein sequence ID" value="PRC91789"/>
        <property type="gene ID" value="S2091_3544"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="51"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="79"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="103"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="136"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="167"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="218"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="246"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="277"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="301"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="342"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="367"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="13"/>
            <end position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC91789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="404" mass="43084" checksum="D3B9F9D2A86A3D6E" modified="2018-07-18" version="1">MKSVTNTRLHPGLIILMSLATGISVASNYYVQPLLHTIAAYFRITNSTAGLIVTSAQIAFALGLMLLVPLADLIERKKLIVVMTLLAGAGMLVTAAAPSIIFVFIGTTVTGMFSVVAQILVPYAATLAQPEERGKIVGHMMSGLLLGILLARTVSGYCSTWFGWQSIYWLGAGMMFITGAVLGRNLPRYHSSIKISYPSLLKSTLTLFIDERVLRIRALLGAIIFCIFSILWTSISFLLANAPFNYSDGTIGLFGLVGAAGALAASRVGKLIDSGKTNLVTSLCIGLLLFSWFPLAVSKSSLLALIIGILLLDLAVQALHITNLSVLNHLSAESRNRLTSGYMTCYFAGGACGSVLSTVLFDYAGWLAVSLCGVTLSLVGVIVWWLSQRDNSSSTSTPAQGHHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVU3</accession>
    <name>A0A2S9GVU3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3401</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000018">
        <property type="protein sequence ID" value="PRC91845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91845">
        <property type="protein sequence ID" value="PRC91845"/>
        <property type="gene ID" value="S2091_3401"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="187" mass="20181" checksum="47BCE2A26E2F2D44" modified="2018-07-18" version="1">MQIENNVFLNFPNQYATQGFSALSKSLNSQVQNAITPTSSTIVTLSSAATANSNSNDNANDVTLPPIQQQIINQLNNSSPSWAMQTVQDVATNPDSELVNISHATFGPNGIQGVVYTNNGEPVTSQSSAQFATLAQQVLTQKTAIFEQGKAEGLSAGQIYTKIQDYMATQPQWYLQQMDWNGSTAQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVY7</accession>
    <name>A0A2S9GVY7_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">PKHD-type hydroxylase S2091_3427</fullName>
            <ecNumber evidence="7">1.14.11.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_3427</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="7">Binds 1 Fe(2+) ion per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>L-ascorbate</name>
            <dbReference type="ChEBI" id="CHEBI:38290"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.11.-" evidence="7"/>
    <dbReference type="EMBL" id="PUGF01000018">
        <property type="protein sequence ID" value="PRC91871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91871">
        <property type="protein sequence ID" value="PRC91871"/>
        <property type="gene ID" value="S2091_3427"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016706">
        <property type="term" value="F:2-oxoglutarate-dependent dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031418">
        <property type="term" value="F:L-ascorbic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00657">
        <property type="entry name" value="Hydroxyl_YbiX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041097">
        <property type="entry name" value="PKHD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023550">
        <property type="entry name" value="PKHD_hydroxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006620">
        <property type="entry name" value="Pro_4_hyd_alph"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044862">
        <property type="entry name" value="Pro_4_hyd_alph_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41536">
        <property type="entry name" value="PTHR41536"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13640">
        <property type="entry name" value="2OG-FeII_Oxy_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18331">
        <property type="entry name" value="PKHD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00702">
        <property type="entry name" value="P4Hc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="6 7" id="KW-0408">Iron</keyword>
    <keyword evidence="2 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0847">Vitamin C</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="8">
        <location>
            <begin position="78"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="97"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="99"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="159"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="169"/>
        </location>
        <ligand>
            <name>2-oxoglutarate</name>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC91871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="227" mass="25536" checksum="43E1CE33EA0B0BB3" modified="2018-07-18" version="1">MLLQLKQILLPEEVTQARTILAHAPWGDGRVTSGAQAAQVKNNSQLPEQCDAAQALQKLVLQGLKRNSAFFSAALPKHISPPLFNHYGGSANNFGDHVDSSVRYLHNGERVRTDISCTLFLSEPHDYCGGELVIADGYRDERIKLAAGDLILYSADRIHRVEAVTEGQRYAGFFWIESMVRQEDQRRMLYAMDTHLINLREQMGETHSAVIGLTSTYHNLLRMWVDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVZ5</accession>
    <name>A0A2S9GVZ5_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF1801 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3448</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000018">
        <property type="protein sequence ID" value="PRC91892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91892">
        <property type="protein sequence ID" value="PRC91892"/>
        <property type="gene ID" value="S2091_3448"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014922">
        <property type="entry name" value="DUF1801"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08818">
        <property type="entry name" value="DUF1801"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF1801" evidence="1">
        <location>
            <begin position="26"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="138" mass="15443" checksum="FEBCB8375760ADAD" modified="2018-07-18" version="1">MQENKTKATDASVESYLSAIEDEARRMDCTALNKLISKALNEPPKMWGASIVGFGSYHYKYESGREGDSCLTGFSSRKGDISIYLVADFPGQDELLERLGKHKRGKGCLYVRQLSEIDLNVLEQLIVGSVAERKLRHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWG3</accession>
    <name>A0A2S9GWG3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3173</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000016">
        <property type="protein sequence ID" value="PRC92038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92038">
        <property type="protein sequence ID" value="PRC92038"/>
        <property type="gene ID" value="S2091_3173"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06259">
        <property type="entry name" value="YdcF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003848">
        <property type="entry name" value="DUF218"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02698">
        <property type="entry name" value="DUF218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF218" evidence="1">
        <location>
            <begin position="52"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="225" mass="24864" checksum="E7547600B0CB16EB" modified="2018-07-18" version="1">MMTKRFICWCVVGSIGLLISCAMLIIVLADWRISDVAKNKIVAQAEQVVDQDVVLVLGTSPQIGSKPNYFYVERIRAVVQLWQLGKVRAVLVSGDNSTPHYNEPDRMKRDLVAAGIPPEFITCDYAGLRTYDSIARAGKIFGLKRVVIVSQREHLERALYLASAMHLDATGLAAADAPNWWQVRQQVREALARVKAMLDIAVELPPKHLGLPIVVPLAPKLATSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWP5</accession>
    <name>A0A2S9GWP5_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 3">Methionine aminopeptidase</fullName>
            <shortName evidence="2">MAP</shortName>
            <shortName evidence="2">MetAP</shortName>
            <ecNumber evidence="2 3">3.4.11.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Peptidase M</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">map</name>
        <name evidence="5" type="ORF">S2091_3059</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 2">Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 3">
            <text>Release of N-terminal amino acids, preferentially methionine, from peptides and arylamides.</text>
            <dbReference type="EC" id="3.4.11.18"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 3">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
        <cofactor evidence="2 3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <cofactor evidence="2 3">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <cofactor evidence="2 3">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="2 3">Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.18" evidence="2 3"/>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92143">
        <property type="protein sequence ID" value="PRC92143"/>
        <property type="gene ID" value="S2091_3059"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046914">
        <property type="term" value="F:transition metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070084">
        <property type="term" value="P:protein initiator methionine removal"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01086">
        <property type="entry name" value="MetAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01974">
        <property type="entry name" value="MetAP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001714">
        <property type="entry name" value="Pept_M24_MAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002467">
        <property type="entry name" value="Pept_M24A_MAP1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00599">
        <property type="entry name" value="MAPEPTIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="SSF55920"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00500">
        <property type="entry name" value="met_pdase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00680">
        <property type="entry name" value="MAP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 5" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 3" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_M24" evidence="4">
        <location>
            <begin position="14"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="85"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="102"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="113"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="176"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="183"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="209"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002521"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC92143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="270" mass="29666" checksum="81ACD2E117CB4407" modified="2018-07-18" version="1">MSAITIKTAEDIQGMRIAGRLGSEVLDYITPYVKVGVTTGELDRLCHEYMVNVQGTIPAPLNYCPPGYTPYPKAICTSVNDVVCHGIPGDKVLKSGDVVNLDITVIKDGYHGDTSRMFFVGEPSIMAKRLSAITFECMWLGISKIKPGNHLGDIGFIIQQYAEKAGYSVVREFCGHGIGKIFHEEPQILHYGRPGTLAEMLPGMIFTVEPMINSGRKEIREMPDGWTIKTRDRSLSAQWEHTVLVTETGYEVLTASAGMPPPPEFISAKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWQ9</accession>
    <name>A0A2S9GWQ9_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Outer membrane protein assembly factor BamA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">bamA</name>
        <name evidence="8" type="ORF">S2091_3070</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Part of the Bam complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the BamA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92154">
        <property type="protein sequence ID" value="PRC92154"/>
        <property type="gene ID" value="S2091_3070"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043165">
        <property type="term" value="P:Gram-negative-bacterium-type cell outer membrane assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051205">
        <property type="term" value="P:protein insertion into membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01430">
        <property type="entry name" value="OM_assembly_BamA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000184">
        <property type="entry name" value="Bac_surfAg_D15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010827">
        <property type="entry name" value="BamA/TamA_POTRA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039910">
        <property type="entry name" value="D15-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023707">
        <property type="entry name" value="OM_assembly_BamA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034746">
        <property type="entry name" value="POTRA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12815">
        <property type="entry name" value="PTHR12815"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12815:SF23">
        <property type="entry name" value="PTHR12815:SF23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01103">
        <property type="entry name" value="Omp85"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07244">
        <property type="entry name" value="POTRA"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006076">
        <property type="entry name" value="OM_assembly_OMP85"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03303">
        <property type="entry name" value="OM_YaeT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51779">
        <property type="entry name" value="POTRA"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 6" id="KW-1134">Transmembrane beta strand</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015792836" description="Outer membrane protein assembly factor BamA" evidence="6">
        <location>
            <begin position="33"/>
            <end position="795"/>
        </location>
    </feature>
    <feature type="domain" description="POTRA" evidence="7">
        <location>
            <begin position="36"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="domain" description="POTRA" evidence="7">
        <location>
            <begin position="104"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="domain" description="POTRA" evidence="7">
        <location>
            <begin position="187"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="domain" description="POTRA" evidence="7">
        <location>
            <begin position="278"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="domain" description="POTRA" evidence="7">
        <location>
            <begin position="359"/>
            <end position="433"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC92154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="795" mass="88197" checksum="47F275A0A0DFCD50" modified="2018-07-18" version="1" precursor="true">MKLHSAYFPLPNFPRRLVAIAAFALSSGSALAIQPFVVKDIRVEGAQRTEAGTIFSYLPVRVGDTFTDEKSIAAIKSLYATGFFKDVQIEAQGNVLVIVLEERPSVGLVEFTGMKEFEKDVLIKALKEIGVGEGRIFDKASVDRAEQELKRQYLSRGLYGVQVTTTVTPIERNRVNINFVVDEGEVARIKKISFIGNKAFSDKELQDNIALRTPGWFTWYSKADQYSKQKLSGDLESLKSFYQNRGYIEMNVDSTQISITPDKKDIYITINLTEGEQYTVTDIRLEGETFGRDAEFKSLLTLKSGETYSAAKLTESTKKITDRMGNFGYAFANVNANPDVDREKKEVAFTIFLDPGKRVYVRKIGFAGNTTTRDEVIRREFRQFEGSWYDGQKIKLSRDRVDRLGYFKEVTIETPEVAGSTDQIDVNLNVVENPTGNFTLGAGYSQAEHFTISGGLSKSNAFGSGDTIGISVNTSQINRTVALSRYEPYLTDDGISRSEEVYLRTNTAPIGSFGGYNVRTIGSDVKFGVPFTELDTIYFGLGVENTKVETKTGSPYRYQKYVTDYGNGQIFYVPENPITGAPSYIDEVPGVAKTFAFPMTMAWQRDSRDSALTPSIGSYQRANLEVALLGDMKYMRTVYQRQYFQPFFSNFATLALNGEIDYGRGFNGNPFPIFKNWYAGGIGSVRGFETSSLGSKDPVTGDSTGGASRLILNAELQFPFPGSANDRSLRWFVFSDAGNVYDEGAAFRGGVKASYGIGISWLSPMGPLKLSLAHAINATDLDRKKPFDFQIGGGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWT4</accession>
    <name>A0A2S9GWT4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Citrate lyase beta subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_3095</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92179">
        <property type="protein sequence ID" value="PRC92179"/>
        <property type="gene ID" value="S2091_3095"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005000">
        <property type="entry name" value="Aldolase/citrate-lyase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040186">
        <property type="entry name" value="Citramalyl-CoA_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011206">
        <property type="entry name" value="Citrate_lyase_beta/mcl1/mcl2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_Kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11105">
        <property type="entry name" value="PTHR11105"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03328">
        <property type="entry name" value="HpcH_HpaI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015582">
        <property type="entry name" value="Cit_lyase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="SSF51621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HpcH_HpaI" evidence="5">
        <location>
            <begin position="46"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="83"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3 4">
        <location>
            <position position="145"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="171"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR015582-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR015582-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC92179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="321" mass="35311" checksum="9F1C414D3F682AAD" modified="2018-07-18" version="1">MHPSNVLFQDDLLPVSLPVCDHYAGSEKLMRKSMILQQESATLFDITFDCEDGAAYGNETAHAQLIAELLESDANHFGRIGVRLHEPSSPFFAQDIQHICTSRKLAYVVLPKVHNVAQLQTAIKAIALQRDFSGLPAIPIHVLIETHGALAEVQQIAALKSVECLSFGIMDFVSAHYGAIPGNAMRTPGQFTHPLVMRAKLDIAAACHLHGKVASHNVTTEFKDTAVVANDAQRAFNECGYSRMWSIHPDQIKPIIKAFAPRSSELQEAITILTAAQAAAWGPIQVNGRLHDRASYRYYWMVLKRAKTNGLALPETALELL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWZ1</accession>
    <name>A0A2S9GWZ1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">RNA polymerase sigma factor RpoE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_3134</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92218">
        <property type="protein sequence ID" value="PRC92218"/>
        <property type="gene ID" value="S2091_3134"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014286">
        <property type="entry name" value="RNA_pol_sigma70_RpoE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02939">
        <property type="entry name" value="RpoE_Sigma70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="3">
        <location>
            <begin position="26"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="4">
        <location>
            <begin position="135"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="92"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="98"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC92218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="200" mass="22819" checksum="B3227A2CD5CB2FA9" modified="2018-07-18" version="1">MTTERDVDQVLVECVQAGDKRAFELLVVKYQRKLMRLILYFVKDHAEAEDVMQETFIKAYRALPNFRGESAFYTWLYRIGVNSAKNHLISQRRRVPTSTDSDAQEAETFKDAGGLRESNTPESILASKQLAATVNEAMNALPEDLRIAISLREIEGLSYDEIADMMDCPIGTVRSRIFRARESIANKIRPLLGTSLDKRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GX52</accession>
    <name>A0A2S9GX52_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 8">Elongation factor G</fullName>
            <shortName evidence="8">EF-G</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">fusA</name>
        <name evidence="10" type="ORF">S2091_2961</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7 8">Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92302">
        <property type="protein sequence ID" value="PRC92302"/>
        <property type="gene ID" value="S2091_2961"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd16262">
        <property type="entry name" value="EFG_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01434">
        <property type="entry name" value="EFG_mtEFG1_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03713">
        <property type="entry name" value="EFG_mtEFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00054_B">
        <property type="entry name" value="EF_G_EF_2_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041095">
        <property type="entry name" value="EFG_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009022">
        <property type="entry name" value="EFG_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035649">
        <property type="entry name" value="EFG_V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000640">
        <property type="entry name" value="EFG_V-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004540">
        <property type="entry name" value="Transl_elong_EFG/EF2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005517">
        <property type="entry name" value="Transl_elong_EFG/EF2_IV"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00679">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14492">
        <property type="entry name" value="EFG_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03764">
        <property type="entry name" value="EFG_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00838">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00889">
        <property type="entry name" value="EFG_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="SSF54980"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00484">
        <property type="entry name" value="EF-G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 8 10" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="6 8" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="9">
        <location>
            <begin position="8"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="17"/>
            <end position="24"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="88"/>
            <end position="92"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="142"/>
            <end position="145"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00017872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC92302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="703" mass="77868" checksum="42B9C4E5C72B7BB5" modified="2018-07-18" version="1">MTRKTPIERYRNIGISAHIDAGKTTTTERILFYTGVNHKIGEVHNGAATMDWMEQEQERGITITSAATTAFWKGMAGNLAEHRINIIDTPGHVDFTIEVERSMRVLDGAVMVYDAVGGVQPQSRTVWRQANKYAVPRIAFVNKMDRVGADFFRVHQQITEHLKGNAVPIQIPLGAEDHFQGVIDLVKMRAISWDDASQGVQFTYEEIPAELKELAQKWRDHMVGAAAEATPELTEKYLNGETLTEDEIKQALRLRTIRNEIVPMLAGSAFKNKGVQAILDAVVDYLPSPADVPAIAGHDEDDNLIERHPLDDEPFSALAFKIMSDPFVGHLTFFRVYSGVVHAGDTVYNPTKSQKERLGRIFQMHANERKEVKDVYAGDIAAAVGLKTVTTGDTLSAPEHVIVLEKMIFPEPVISQAVEPKTKVDQEKMGVALNRLAQEDPSFRVHTDQESGQTIIAGMGELHLEILVDRMKREFGVDATVGKPQVAYRETIRKQVSDVEGKFIKQSGGKGQYGHVVLKLEPMEPGKGYEFVDAIKGGVVPREFIPAVDKGIQETLRSGVLAGYPVVDVRVSLTFGSYHDVDSNENAFRMAGSMAFKDGMRRADPQLLEPMMQVEVETPEEFMGNAMGDLTSRRGMVQGTDEIPGGGGKLIKALVPLAEMFGYSTTLRSLSQGRATYTMEFKHYAIVPKHILEQVMVKAATKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXG3</accession>
    <name>A0A2S9GXG3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Plasmid stabilization system protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2784</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92409">
        <property type="protein sequence ID" value="PRC92409"/>
        <property type="gene ID" value="S2091_2784"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2310.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007712">
        <property type="entry name" value="RelE/ParE_toxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035093">
        <property type="entry name" value="RelE/ParE_toxin_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05016">
        <property type="entry name" value="ParE_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-1277">Toxin-antitoxin system</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="96" mass="10924" checksum="003439573638233C" modified="2018-07-18" version="1">MRIKFLEQAKADLAEHNDYYRKLGGVALASKMMDRIKGPVLALKDNPAIAQSYELAPDMRRLVVARGAFLVFYRVDVDIEVLHILRAERIPLSDPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXI9</accession>
    <name>A0A2S9GXI9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3035</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92376">
        <property type="protein sequence ID" value="PRC92376"/>
        <property type="gene ID" value="S2091_3035"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="83" mass="8459" checksum="47E0282B6A426917" modified="2018-07-18" version="1">MTFASASLKGLGITLLFAIAVSLQATTSVDIKAKLSAIPTSTPVATLNTNKNTVSLDVISMADPHAVFVAQPSVPDALGGAYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXN5</accession>
    <name>A0A2S9GXN5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alpha/beta hydrolase fold</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2846</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S33 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92471">
        <property type="protein sequence ID" value="PRC92471"/>
        <property type="gene ID" value="S2091_2846"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002410">
        <property type="entry name" value="Peptidase_S33"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00793">
        <property type="entry name" value="PROAMNOPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="2">
        <location>
            <begin position="53"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="436" mass="48671" checksum="480D2895293C9345" modified="2018-07-18" version="1">MSDSFRMDDVVCIDHWLTVPLDYAQPNGPQIRIYGRELVLRLQANIPQLPWALFLQGGPGFESPRPMGRAGWLTPILIGHRLFLLDQRGTGRSSALSTKQIAAIGTPQQQAEQLRHYRQDNIVRDAEAFRKHLTKEKPWLVIGQSFGGFCAATYLSHAPEGIAAVILTGALPPVGWQIDDVYRVTYRLAERASLHLYERIPALQIQFTRLAELLSRQPAKLPNGGILTVRGLQSLGLQLYRAQGAYTLAYLLERAFPNGSDQAPVCTDAFLSAVTPLLATFASNPFFLLLHEAIYADGAGQATNWSAQRIRKEFPQFDQFDGTTLLLTAEHMYPWMADEFPGSAQLAEVAEILAKKSDWEPLYDASRLQANTIPIAAVVYYDDLCCGFDYSIDFANRLGGIKRWITSEFAHDGIHTDGEHIMWRLLGMLEGDIPSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXW4</accession>
    <name>A0A2S9GXW4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC-type sugar transport system periplasmic component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_2622</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial solute-binding protein 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92567">
        <property type="protein sequence ID" value="PRC92567"/>
        <property type="gene ID" value="S2091_2622"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008643">
        <property type="term" value="P:carbohydrate transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006059">
        <property type="entry name" value="SBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006061">
        <property type="entry name" value="SBP_1_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01547">
        <property type="entry name" value="SBP_bac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01037">
        <property type="entry name" value="SBP_BACTERIAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015785067" evidence="4">
        <location>
            <begin position="32"/>
            <end position="415"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC92567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="415" mass="45179" checksum="CB967B6AA77CF8FA" modified="2018-07-18" version="1">MKFISSTAQIQSALACLCIAASLFGVTQAQAETVQTVRIAVAHYSDQTLPYFQKMAKEFNKTNPGITIKIEEVNWDNLQQKLQTDISSGTNPDLSIVGTRWLLDLVKDDVLEPLAGHMTAPFKDRFIGEFLNSGNINGQVYGLPIAASARGLYYNKIMLKNAGFPNGPKTWDDVFAASKKIKANGAYGFGLQGKEIETEVYWFYALWSQGGTIIDANGKAVFDSAAGIKAASMYKELINQGLTQPGVTSYSREDVQNLFKQGRVAMVITAPFLAKQIQKENPALQYGVTAVPGDVASATYATTDSLVMFKNSKVKAAAWKFADFLFSKAPRVTFTSSEGFLPTTKEEASDPVFADDVTKEFIGFLPTAKFPPVIAGWEDLSKILSNALQSIYLGKTKPDVALKAAAAQTNHVLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GY66</accession>
    <name>A0A2S9GY66_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2695</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92640">
        <property type="protein sequence ID" value="PRC92640"/>
        <property type="gene ID" value="S2091_2695"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="55" mass="5973" checksum="31304CF42D787C91" modified="2018-07-18" version="1">MTDEIKPLTTEVAHLTPPEMRLIKLFREATAGGKSLITTMAEEAPKESTAANDES</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYF0</accession>
    <name>A0A2S9GYF0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2479</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92749">
        <property type="protein sequence ID" value="PRC92749"/>
        <property type="gene ID" value="S2091_2479"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="102"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="130"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="194"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="382" mass="43039" checksum="4C3BE9784E393003" modified="2018-07-18" version="1">MTPTTLLLICVVLTDLALNFMLVPFYFQHGIVVFRRKIKCDQRETPIPSIAQIEVRIPSSIWPDFLLKEIDPIQFAFRERVFKSMMTYTPIMHGVLRLDTESGYVVVTGRLNWTTLAFIVFAFFNLSDHVDLSFGFMALLILSVIYLIQAIRYSQIANTAAIIWRESSSQNQDQSNANFNLNASDHVQSRSFRLANIPAGAVVGIGIASFVLAIHFIGAKQDPYGDLETAFKSTNYLQTKAISPTSVGFTSPDRKYSKYKGTMDIRLSADAMELDPTFPSSISNKKIVVPMNRIAACSRTCSGDNTWSADILIDNPATEIAVTQSQEVLEWCWDNHIPMVSGKDRRAFVYTRTPVPERSRYTEQLSSKAIYMEQGRQSCLGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYH5</accession>
    <name>A0A2S9GYH5_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Phosphonoacetaldehyde hydrolase</fullName>
            <shortName evidence="2">Phosphonatase</shortName>
            <ecNumber evidence="2">3.11.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Phosphonoacetaldehyde phosphonohydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">phnX</name>
        <name evidence="3" type="ORF">S2091_2507</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Involved in phosphonate degradation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>H2O + phosphonoacetaldehyde = acetaldehyde + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:18905"/>
            <dbReference type="ChEBI" id="CHEBI:15343"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58383"/>
            <dbReference type="EC" id="3.11.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="2">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the HAD-like hydrolase superfamily. PhnX family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.11.1.1" evidence="2"/>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92777">
        <property type="protein sequence ID" value="PRC92777"/>
        <property type="gene ID" value="S2091_2507"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050194">
        <property type="term" value="F:phosphonoacetaldehyde hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019700">
        <property type="term" value="P:organic phosphonate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02586">
        <property type="entry name" value="HAD_PHN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01375">
        <property type="entry name" value="PhnX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006323">
        <property type="entry name" value="Phosphonoacetald_hydro"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01509">
        <property type="entry name" value="HAD-SF-IA-v3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01422">
        <property type="entry name" value="phosphonatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0704">Schiff base</keyword>
    <feature type="active site" description="Nucleophile" evidence="2">
        <location>
            <position position="24"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with substrate" evidence="2">
        <location>
            <position position="65"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="24"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="26"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="199"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="282" mass="30554" checksum="208952DBB18B3E32" modified="2018-07-18" version="1">MTQHHQDYRYTRHYQGQVQAVIFDWAGTLVDFGSFAPTRILIDAFAGFGITITLSEARIPMGLGKWDHIKALGQQPAVAQRWVAHHGRDMTDSDVDAIYAAFLPLQIARVGEYSDVIPGALEVLADLAERGIRRGSCSGYPRVVMDKLLEHAAQKGVIVEHAVATDDLPHGGRPGPWMALANVIALGAGDVSACVKVDDTTPGIEEGLAAGMWTVGLALSGNEVGLTLQELKTLPPAEVERKRAFAYQKLMRAGAHFVIDTIADLPAILDLIESRMVKGERP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYM7</accession>
    <name>A0A2S9GYM7_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">tRNA uridine(34) hydroxylase</fullName>
            <ecNumber evidence="1">1.14.-.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">tRNA hydroxylation protein O</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">trhO</name>
        <name evidence="3" type="ORF">S2091_2538</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>AH2 + O2 + uridine(34) in tRNA = 5-hydroxyuridine(34) in tRNA + A + H2O</text>
            <dbReference type="Rhea" id="RHEA:64224"/>
            <dbReference type="Rhea" id="RHEA-COMP:11727"/>
            <dbReference type="Rhea" id="RHEA-COMP:13381"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:136877"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the TrhO family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.-.-" evidence="1"/>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92808">
        <property type="protein sequence ID" value="PRC92808"/>
        <property type="gene ID" value="S2091_2538"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00469">
        <property type="entry name" value="TrhO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020936">
        <property type="entry name" value="TrhO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040503">
        <property type="entry name" value="TRHO_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43268">
        <property type="entry name" value="PTHR43268"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17773">
        <property type="entry name" value="UPF0176_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="SSF52821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Rhodanese" evidence="2">
        <location>
            <begin position="133"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="297" mass="33771" checksum="F0FA9A3133F90E63" modified="2018-07-18" version="1">MQSSTPQYINISAYKFITFNDTAEKRPEFLAICQQLNLKGTILLTPEGINLFLAGLRHEIDGFMDWLHTDPRFSDVVAKESISDSQPFTKLLIKLKAETITMRMPLIRPEDGRAPFVAPTTLKRWLDQGHDDTGRPVVMVDTRNDFEVDVGSFNNTVDFRIKKFTEFPEVIAANKDELNDKTVVTFCTGGIRCEKAAIHMQNVGYEHVYQLEGGILKYFEEVGGDHYHGDCFVFDYRTALNPQLEATDTEQCYACRAVVTPREQLSPYYIPGKSCPHCKKQCREEITPTVEIEAKLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYR8</accession>
    <name>A0A2S9GYR8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Outer membrane insertion C-terminal signal</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2578</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92848">
        <property type="protein sequence ID" value="PRC92848"/>
        <property type="gene ID" value="S2091_2578"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011250">
        <property type="entry name" value="OMP/PagP_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023614">
        <property type="entry name" value="Porin_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56925">
        <property type="entry name" value="SSF56925"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015709450" evidence="2">
        <location>
            <begin position="24"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="146" mass="16044" checksum="67679C9CE2293C69" modified="2018-07-18" version="1">MATQSHYIHPIALLACIASPASAELPLTIEDLLTDKGKVTFDATYSYANNNQQGIAVGEPIIVQTGPTSFITIPTRIGETRTDIDTSAVTLGLRYGLSKDTELYGRGSYLWNNTRSSNFSDLSNSNSQQFSDAWLGLNYRFLKDEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYS9</accession>
    <name>A0A2S9GYS9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2302</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92885">
        <property type="protein sequence ID" value="PRC92885"/>
        <property type="gene ID" value="S2091_2302"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012545">
        <property type="entry name" value="DUF1697"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36439">
        <property type="entry name" value="PTHR36439"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08002">
        <property type="entry name" value="DUF1697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF008502">
        <property type="entry name" value="UCP008502"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="180" mass="19922" checksum="DF5C1D5038E155C8" modified="2018-07-18" version="1">MKTWIALLRGINVGGRNKLPMKALAAELESLGLSDIKTYIQSGNVVFRGSDTRARNIATSIGAAIHAKFGFEPPVIVISDKDLADAITANPFPESTTEKEGRTLHFFFLDKAPSNIDHDRLESVRRPSERWQVKGTVLYLHTPEGFGDSKLAVQIERIFGVTATARNWRTVCALRDLSVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZ12</accession>
    <name>A0A2S9GZ12_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="12">MotA1: flagellar motor stator protein MotA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">S2091_2382</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MotA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92965">
        <property type="protein sequence ID" value="PRC92965"/>
        <property type="gene ID" value="S2091_2382"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097588">
        <property type="term" value="P:archaeal or bacterial-type flagellum-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006811">
        <property type="term" value="P:ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000540">
        <property type="entry name" value="Flag_MotA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022522">
        <property type="entry name" value="Flagellar_motor_stator_MotA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002898">
        <property type="entry name" value="MotA_ExbB_proton_chnl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30433:SF4">
        <property type="entry name" value="PTHR30433:SF4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01618">
        <property type="entry name" value="MotA_ExbB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03818">
        <property type="entry name" value="MotA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01307">
        <property type="entry name" value="MOTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="12" id="KW-0966">Cell projection</keyword>
    <keyword evidence="12" id="KW-0969">Cilium</keyword>
    <keyword evidence="6" id="KW-0283">Flagellar rotation</keyword>
    <keyword evidence="12" id="KW-0282">Flagellum</keyword>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="171"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="201"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="domain" description="MotA_ExbB" evidence="11">
        <location>
            <begin position="129"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PRC92965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="286" mass="30988" checksum="7C0BD25D7B6FE1FC" modified="2018-07-18" version="1">MLVIVGYILVVGSVFGGFAMAGGHLAALFQPLELLMIGGAAVGASMVGNNVKTLKASLKALPGVLKGSKYNKTMYLELMTMLFDVLSKVRKEGLMSIEGDIEKPEESPLFSKYEKVVHDHHLMEFICDYLRLMVSGNMDAFQIENLMDNEIETHHIEAHAPVHFVAKLGDGLPAFGIVAAVMGVVHTMESVGIPPSELGELIAHALVGTFLGILLAYGFVGPLSGLLEQQLDESSKTFQCVKVTLLASLNGFAPALAIEFGRKVLYSTERPSFIELEDHIKQNKSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZ39</accession>
    <name>A0A2S9GZ39_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Phosphoserine aminotransferase</fullName>
            <ecNumber evidence="9">2.6.1.52</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Phosphohydroxythreonine aminotransferase</fullName>
            <shortName evidence="9">PSAT</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">serC</name>
        <name evidence="12" type="ORF">S2091_2419</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>2-oxoglutarate + 4-(phosphooxy)-L-threonine = (R)-3-hydroxy-2-oxo-4-phosphooxybutanoate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:16573"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58452"/>
            <dbReference type="ChEBI" id="CHEBI:58538"/>
            <dbReference type="EC" id="2.6.1.52"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 9 10">
            <text>2-oxoglutarate + O-phospho-L-serine = 3-phosphooxypyruvate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:14329"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:18110"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57524"/>
            <dbReference type="EC" id="2.6.1.52"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
        <text evidence="9">Binds 1 pyridoxal phosphate per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 9 10">Amino-acid biosynthesis; L-serine biosynthesis; L-serine from 3-phospho-D-glycerate: step 2/3.</text>
    </comment>
    <comment type="pathway">
        <text evidence="9">Cofactor biosynthesis; pyridoxine 5'-phosphate biosynthesis; pyridoxine 5'-phosphate from D-erythrose 4-phosphate: step 3/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 9">Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.52" evidence="9"/>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC93002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93002">
        <property type="protein sequence ID" value="PRC93002"/>
        <property type="gene ID" value="S2091_2419"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00135">
        <property type="reaction ID" value="UER00197"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00244">
        <property type="reaction ID" value="UER00311"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004648">
        <property type="term" value="F:O-phospho-L-serine:2-oxoglutarate aminotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006564">
        <property type="term" value="P:L-serine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008615">
        <property type="term" value="P:pyridoxine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00611">
        <property type="entry name" value="PSAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00160">
        <property type="entry name" value="SerC_aminotrans_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020578">
        <property type="entry name" value="Aminotrans_V_PyrdxlP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022278">
        <property type="entry name" value="Pser_aminoTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43247">
        <property type="entry name" value="PTHR43247"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000525">
        <property type="entry name" value="SerC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01364">
        <property type="entry name" value="serC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00595">
        <property type="entry name" value="AA_TRANSFER_CLASS_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5 9 10" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 9" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="7 9" id="KW-0664">Pyridoxine biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 9 10" id="KW-0718">Serine biosynthesis</keyword>
    <keyword evidence="9 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_5" evidence="11">
        <location>
            <begin position="2"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="region of interest" description="Pyridoxal phosphate binding" evidence="9">
        <location>
            <begin position="243"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="40"/>
        </location>
        <ligand>
            <name>L-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="105"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="159"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="178"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="201"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="9">
        <location>
            <position position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001871"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PRC93002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="367" mass="40069" checksum="6AD1056ED222472A" modified="2018-07-18" version="1">MIYNFSAGPAVLPKEVLQQAAAEMLDWHGSGMSVMEMSHRGTEFMSILANAQQDLRELLAVPSNYKILFMQGGAIAENAIVPLNLAGLGNRAQPATLDYICTGSWSVKSIKEAAKYGTVNVAADARTFSPDGKFSSIPAPSNWQLSSDAAYLHICTNETIDGVEYGFTPNVSMPIVADMSSHILSRVISVSDYGVIYGGAQKNIGPAGLTIVIVREDLLGYALPACPSAFNWKTVADNDSMFNTPPTYAIYIAGLVFQWIKRQGGVAALEKINVAKAALLYDYLDNSRLYENRIVKDCRSRMNVPFFLRDESLNAIFLSEAKARGLLQLKGHSSVGGMRASIYNAMPIEGVQALVAFMDEFERQYFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZ48</accession>
    <name>A0A2S9GZ48_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">3-phosphoshikimate 1-carboxyvinyltransferase</fullName>
            <ecNumber evidence="7">2.5.1.19</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">5-enolpyruvylshikimate-3-phosphate synthase</fullName>
            <shortName evidence="7">EPSP synthase</shortName>
            <shortName evidence="7">EPSPS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">aroA</name>
        <name evidence="9" type="ORF">S2091_2422</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>3-phosphoshikimate + phosphoenolpyruvate = 5-O-(1-carboxyvinyl)-3-phosphoshikimate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:21256"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57701"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:145989"/>
            <dbReference type="EC" id="2.5.1.19"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 6/7.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the EPSP synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.19" evidence="7"/>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC93005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93005">
        <property type="protein sequence ID" value="PRC93005"/>
        <property type="gene ID" value="S2091_2422"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00053">
        <property type="reaction ID" value="UER00089"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003866">
        <property type="term" value="F:3-phosphoshikimate 1-carboxyvinyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:cellular amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009423">
        <property type="term" value="P:chorismate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01556">
        <property type="entry name" value="EPSP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.65.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00210">
        <property type="entry name" value="EPSP_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001986">
        <property type="entry name" value="Enolpyruvate_Tfrase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036968">
        <property type="entry name" value="Enolpyruvate_Tfrase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006264">
        <property type="entry name" value="EPSP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023193">
        <property type="entry name" value="EPSP_synthase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013792">
        <property type="entry name" value="RNA3'P_cycl/enolpyr_Trfase_a/b"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00275">
        <property type="entry name" value="EPSP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000505">
        <property type="entry name" value="EPSPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55205">
        <property type="entry name" value="SSF55205"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01356">
        <property type="entry name" value="aroA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00104">
        <property type="entry name" value="EPSP_SYNTHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00885">
        <property type="entry name" value="EPSP_SYNTHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6 7" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="EPSP_synthase" evidence="8">
        <location>
            <begin position="14"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="region of interest" description="Shikimate-3-phosphate binding" evidence="7">
        <location>
            <begin position="28"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Phosphoenolpyruvate" evidence="7">
        <location>
            <begin position="99"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Shikimate-3-phosphate binding" evidence="7">
        <location>
            <begin position="175"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="322"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="7">
        <location>
            <position position="350"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="33"/>
        </location>
        <ligand>
            <name>3-phosphoshikimate</name>
            <dbReference type="ChEBI" id="CHEBI:145989"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="129"/>
        </location>
        <ligand>
            <name>phosphoenolpyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="205"/>
        </location>
        <ligand>
            <name>3-phosphoshikimate</name>
            <dbReference type="ChEBI" id="CHEBI:145989"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="349"/>
        </location>
        <ligand>
            <name>3-phosphoshikimate</name>
            <dbReference type="ChEBI" id="CHEBI:145989"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="353"/>
        </location>
        <ligand>
            <name>phosphoenolpyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="395"/>
        </location>
        <ligand>
            <name>phosphoenolpyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="425"/>
        </location>
        <ligand>
            <name>phosphoenolpyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC93005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="440" mass="47482" checksum="22F98BBC0B779258" modified="2018-07-18" version="1">MKIPHFPPYIDLNPVTRTQGAIQLPGSKSISNRTLLLAALAEGNTEISELLASDDTLVMLNALQTLGVQWQQKGISQDYLVHGVDGKFPIKQADLFMGNAGTAIRPLVAALSVLGGNYTLHGVQRMHERPIGDLVDALRRVGSDIAYTGLPGFPPLHIQSGQIRPQGWKVAGNVSSQFLTALLMAAPLIICDHDIVIEVVGELISKPYIEITLNLMQRFGVHVERDGWQRFTIARGQYYQSPGSIHVEGDASSASYFLAAGAICGGPVRVTGVGRNSIQGDVRFVEALEKMGASITMGDNFIEARSNGALKAIDADFNAIPDAAMTIAIAALYADGTSVLRNIASWRVKETDRIDAMATELTKLGAQVETGIDYLAITPPAQLKPASIETYDDHRMAMCFSLATLNGALRAGTKVRILDPKCVAKTFPEYFSVFAAIKQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZQ8</accession>
    <name>A0A2S9GZQ8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_1935</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93197">
        <property type="protein sequence ID" value="PRC93197"/>
        <property type="gene ID" value="S2091_1935"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000485">
        <property type="entry name" value="AsnC-type_HTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019888">
        <property type="entry name" value="Tscrpt_reg_AsnC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019887">
        <property type="entry name" value="Tscrpt_reg_AsnC/Lrp_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01037">
        <property type="entry name" value="AsnC_trans_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13404">
        <property type="entry name" value="HTH_AsnC-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00033">
        <property type="entry name" value="HTHASNC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00344">
        <property type="entry name" value="HTH_ASNC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50956">
        <property type="entry name" value="HTH_ASNC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH asnC-type" evidence="4">
        <location>
            <begin position="5"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC93197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="148" mass="16265" checksum="21F9A1EA925EC191" modified="2018-07-18" version="1">MNAKIDNYDQKILGLLQQDARISHAEIGRQIHLSQPSVSERIKRLESSGVIRGYHANINPDAFGYQITAMIRLSTQQGRPYADFVATQPEIIDCYTVTGEDGAVMRVLATDVAHLQRLIDKLNRYGSTSTAIVLTTHVAGKAVSMPVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZX4</accession>
    <name>A0A2S9GZX4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Di-hem cytochrome c peroxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_1986</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93248">
        <property type="protein sequence ID" value="PRC93248"/>
        <property type="gene ID" value="S2091_1986"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004852">
        <property type="entry name" value="Di-haem_cyt_c_peroxidsae"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03150">
        <property type="entry name" value="CCP_MauG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0349">Heme</keyword>
    <keyword evidence="3 4" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="49"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="6">
        <location>
            <begin position="140"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="6">
        <location>
            <begin position="360"/>
            <end position="537"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC93248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="550" mass="59794" checksum="07FE6E796566D94E" modified="2018-07-18" version="1">MTYDNLMTCGNIFIIKLLIFQFIKLTYLSVTLGDFNLRARRQLLLTNRLITTIYDLFITMSMLIPVVSERRAVTSKLALPLLVSCTVFLFAACGHSEKSAATVAISAASAPTTVPAATPAELAAKGAQNRLSAPAQPLSAVAELGKKIFYDASLSASGKLSCASCHSPDNAYAPANNLAVQLGGTGMQQQGGRAVPSLKYHEHTPPFSIGPDLKPEADDIEAERQALAANAAVRAPLAIHAKADLAQAAGAPAVVQENVPQGGFDWDGRAQNLTDQAGGPLMAANEMANKDTHSLLDKFKKSPYANDFLQLFGPSVFSSPNIVLGEAYFALARFQTEDRSFHPYDSKYDYYLAQKVALSAQEERGLTLFKDPKKGNCASCHLEKPSRDGVLAPAFTDYQFEALGAPRNKDIVANRNPHYADLGMCGPLRQDAAKMQNYCGFFKTPSLRNTATRQVFFHNGVFKSLDEVMHFYVERETQPEKWYPSAHGKVEKYNDIPASKRSSVDVTDAPFNSKLGDQAALSDEEIKDVIAFLKTLTDGYKLNATVSAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H081</accession>
    <name>A0A2S9H081_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">VOC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1764</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93377">
        <property type="protein sequence ID" value="PRC93377"/>
        <property type="gene ID" value="S2091_1764"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041581">
        <property type="entry name" value="Glyoxalase_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18029">
        <property type="entry name" value="Glyoxalase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="9"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="158" mass="16858" checksum="205B41EFE5E47E6D" modified="2018-07-18" version="1">MSVKSPPAGFHSITPALAIKGAARAIEFYKEIFGAVVVSRYASPDGVVGHAELKIGDSHIMVSDEYPDFGSVSPLSLGGSPVTFMLYMDDVDSVVECAVAAGATLQRPVADQFHGDRTGTITDPFGHKWTIAKHIEDVSSTELSKRAQELFGMSLTKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H088</accession>
    <name>A0A2S9H088_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1786</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93399">
        <property type="protein sequence ID" value="PRC93399"/>
        <property type="gene ID" value="S2091_1786"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="14"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="332" mass="36964" checksum="FED17C1FA2C31C39" modified="2018-07-18" version="1">MRNSASEKFVRHYLKIKHLVLMVELGRHGSISRAAQSVHMTQSAVSKLLAEIEYALNVTLFERQPRGIFPTRYGEVMIRRAEAALNEMTVAQQEIDERRSGLCGRVALGTVLAPSISVVPRAIQILKQRYARINVSVTVDTSVQLLQKLRSAELDLVIGHQLNPDEEFTFEAIRDEPHSLFVRAGHPWLTHTDLSLKSLLEGSWILPSPGSILRARLTNLFLAQGLDCPSGTVETEDISLISVLLADSNMIVALPREAMRVYLDAGLLDELPFQLGIGLEAYGFMMRSRCRLSLSAELMLDALRASQAMRLMESPARTGLAPTFHFHIPTIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0F3</accession>
    <name>A0A2S9H0F3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative addiction module component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1825</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93438">
        <property type="protein sequence ID" value="PRC93438"/>
        <property type="gene ID" value="S2091_1825"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013406">
        <property type="entry name" value="CHP02574_addiction_mod"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09720">
        <property type="entry name" value="Unstab_antitox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="74" mass="8206" checksum="3F8FE3364BB1F6A6" modified="2018-07-18" version="1">MFSNIESLETEALCLPVEQRANLVKKLIANLDAEPAIEAAWVSEVLRRHAEIEAGTVALLPGTETMARLRTEFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0K8</accession>
    <name>A0A2S9H0K8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="10">TonB-dependent Receptor Plug Domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">S2091_1783</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93396">
        <property type="protein sequence ID" value="PRC93396"/>
        <property type="gene ID" value="S2091_1783"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="3 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 10" id="KW-0675">Receptor</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="2 6" id="KW-0798">TonB box</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015698143" evidence="7">
        <location>
            <begin position="30"/>
            <end position="962"/>
        </location>
    </feature>
    <feature type="domain" description="Plug" evidence="9">
        <location>
            <begin position="56"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="8">
        <location>
            <begin position="377"/>
            <end position="960"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC93396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="962" mass="103478" checksum="2A553D17EA267DE7" modified="2018-07-18" version="1">MEFKNKLRITPIKFAVSILVGSACVVAHADPTQSDPDDKVTKVIITGSNIKTVDTETASPVQVITRADITRQGVSTVADLIGNISGSTGGLSDLGGSNSFAPGASNVSLRNLGPQSTLVLVNGRRISSYGFADYTNVFSNVDAIPLDAVERVEILKSGASAIYGSDAVAGVINIITRTNFQGLEVNADAVKSLQSHTFGTNKASITTGFGDMNKDGYNILLNADFLKRDNVMWTNLEQYTNPDLTKTSPGFGTFSSYSTPGNIIDGPNTQPVAGCAPSLIIGGLCKYNRYQRFQAVPESERANFFSTGTFKLEGGIEAFSEISFSRNTTKYLGAFPYYGDGLAPTQWGNPSTGKSLVFNELGLAANSPLNPTGDDGVGFRYRFTDAPDYQDVTATQFRVLGGLRGNINQYEWESALGVMGSKAVQSSQGTFSSAGFIQEIGNYNNFRLNNNPNVNLAYTASDPNFFAQPGGYHPGQVNSPAVLNTLFPVYGNTGDTKAEFADAKITGPLFKVPAGMINFAAGGEIRHESMSIQPTSNLLDGDIVGYGISAADSSRNIESAYSELSIPLAKDLEMQAALRADKYPNLATHFSPKLALRYAVTDSLLLRGTYENGFRAPNLIESANSVKFAYANGTADPQRCPQASALSNSLYAQAAALPANDPQAAVLNARAESVWAQECSFGLASEVRNNPNLQPESSKSFSFGAVYEPVKGYSTSLDYWHIDRRNTIGTPSTSQLLNGGPLPAGVQINRVPFNSGGDQTFSATELTQYGVTTGPLQNMTLQMENIFQQSTSGIDIAFKGNQNLGSWGKLLEILDGTYNMTYYDTSVSTANENLTGQYDMPQMVANFTLGWDYKGFSNSLRYNYTGGYDLQYGQNDTTWSLKGCATNGFSASQCRVASARTTDYALSYSGFKNLVLKMNLLNMFQQRAPADLRAFGVGGIIPSSLQDAEGRMLRLSVDYKFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0N7</accession>
    <name>A0A2S9H0N7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ferritin-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1813</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93426">
        <property type="protein sequence ID" value="PRC93426"/>
        <property type="gene ID" value="S2091_1813"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012347">
        <property type="entry name" value="Ferritin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026820">
        <property type="entry name" value="VioB/RebD_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12902">
        <property type="entry name" value="Ferritin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="SSF47240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ferritin-like" evidence="1">
        <location>
            <begin position="25"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="368" mass="40106" checksum="6FB930999E5733CA" modified="2018-07-18" version="1">MQVLNQKYIQELQKTEQLSDIHRALTYAVQLELATIPPYLTALFSLKNGSNQQIASLLQSIVVEEMLHMTLAANTLIAIGGNPDLLALGMELQYPGPLPLSVDDGLIVSLAAVSPSQVQQVFMAIEKPDSQEILPGETTPAPPPKIPGEFASIGNFYHAILQGLAHLERQGGHCFAKPRLEQQVNVSLWFPGLRAANPSGKVHDLSTATKVLETIMVQGEGMPFRGDFSPVDPTDSSYAHYFKFGEIFHEQRLIRDPFAPSGWSYSGENVPLDSANVYSFLPNAALSDYPKDSGAGVAANQFYGTYQRLLTSLNLVFNGHPEALRAAMGVMYELKLAAQKVVQHPADPLKPEIIAAPPFMLTKTTNLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H100</accession>
    <name>A0A2S9H100_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">50S ribosomal protein L13</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rplM</name>
        <name evidence="5" type="ORF">S2091_1666</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uL13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93665">
        <property type="protein sequence ID" value="PRC93665"/>
        <property type="gene ID" value="S2091_1666"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00392">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01366">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005822">
        <property type="entry name" value="Ribosomal_L13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005823">
        <property type="entry name" value="Ribosomal_L13_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036899">
        <property type="entry name" value="Ribosomal_L13_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11545">
        <property type="entry name" value="PTHR11545"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00572">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002181">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52161">
        <property type="entry name" value="SSF52161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01066">
        <property type="entry name" value="rplM_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC93665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="142" mass="15964" checksum="A0135971D97E43D8" modified="2018-07-18" version="1">MKTFSAKAHEVQRDWFVIDATDKILGRVASEVALRLRGKHKPEFTPHVDTGDFIVVVNAGKLRVTGTKALNKTYYRHTGYPGGIYETNFQKMQERFPGRALEKAVKGMLPKGPLGYAMIKKLKVYAEATHPHSAQQPKVLEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H116</accession>
    <name>A0A2S9H116_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Protein-export membrane protein SecF</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">secF</name>
        <name evidence="10" type="ORF">S2091_1641</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the SecD/SecF family. SecF subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93640">
        <property type="protein sequence ID" value="PRC93640"/>
        <property type="gene ID" value="S2091_1641"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015450">
        <property type="term" value="F:protein-transporting ATPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0065002">
        <property type="term" value="P:intracellular protein transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006605">
        <property type="term" value="P:protein targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043952">
        <property type="term" value="P:protein transport by the Sec complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01464_B">
        <property type="entry name" value="SecF_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022813">
        <property type="entry name" value="SecD/SecF_arch_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022645">
        <property type="entry name" value="SecD/SecF_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022646">
        <property type="entry name" value="SecD/SecF_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005665">
        <property type="entry name" value="SecF_bac"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30081">
        <property type="entry name" value="PTHR30081"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07549">
        <property type="entry name" value="Sec_GG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02355">
        <property type="entry name" value="SecD_SecF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01755">
        <property type="entry name" value="SECFTRNLCASE"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00916">
        <property type="entry name" value="2A0604s01"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00966">
        <property type="entry name" value="3a0501s07"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0811">Translocation</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="138"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="162"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="189"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="249"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="275"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC93640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="313" mass="34449" checksum="878B2B6CA3E89378" modified="2018-07-18" version="1">MELFRIKKDIPFMRHALIFNVISALTFVAAVFFLLHRGLNLSIEFTGGTEMVVSYDQAAKVDVVKQTLEQLGFHDTSASTFGRAQDVLIRLPAPKAGESTGEQTDAVIAALQKHDASATKKRFSVVGPQVGEELWTNGMYALLMVIVGVAIYLAIRFEWKYAVSAIIANLHDVVIILGFFAFFQWEFSLSVLAGVLAVLGYSVNESVVIFDRIRENFRKQRKTSVTEVIDSAITSTISRTIITHGSTQMMVLSMYFFGGATLHGFSMALTIGICFGIYSSVFVAAAIAMWLGVKREDLIKPIKPKDETDGAVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H119</accession>
    <name>A0A2S9H119_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Queuine tRNA-ribosyltransferase</fullName>
            <ecNumber evidence="4">2.4.2.29</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Guanine insertion enzyme</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">tRNA-guanine transglycosylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">tgt</name>
        <name evidence="6" type="ORF">S2091_1644</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>7-aminomethyl-7-carbaguanine + guanosine(34) in tRNA = 7-aminomethyl-7-carbaguanosine(34) in tRNA + guanine</text>
            <dbReference type="Rhea" id="RHEA:24104"/>
            <dbReference type="Rhea" id="RHEA-COMP:10341"/>
            <dbReference type="Rhea" id="RHEA-COMP:10342"/>
            <dbReference type="ChEBI" id="CHEBI:16235"/>
            <dbReference type="ChEBI" id="CHEBI:58703"/>
            <dbReference type="ChEBI" id="CHEBI:74269"/>
            <dbReference type="ChEBI" id="CHEBI:82833"/>
            <dbReference type="EC" id="2.4.2.29"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="4">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">tRNA modification; tRNA-queuosine biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the queuine tRNA-ribosyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.29" evidence="4"/>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93643">
        <property type="protein sequence ID" value="PRC93643"/>
        <property type="gene ID" value="S2091_1644"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00392"/>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008479">
        <property type="term" value="F:queuine tRNA-ribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008616">
        <property type="term" value="P:queuosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0101030">
        <property type="term" value="P:tRNA-guanine transglycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.105">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00168">
        <property type="entry name" value="Q_tRNA_Tgt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004803">
        <property type="entry name" value="TGT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036511">
        <property type="entry name" value="TGT-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002616">
        <property type="entry name" value="tRNA_ribo_trans-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01702">
        <property type="entry name" value="TGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51713">
        <property type="entry name" value="SSF51713"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00430">
        <property type="entry name" value="Q_tRNA_tgt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00449">
        <property type="entry name" value="tgt_general"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0671">Queuosine biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4 6" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 4" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="TGT" evidence="5">
        <location>
            <begin position="14"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="4">
        <location>
            <begin position="92"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="RNA binding" evidence="4">
        <location>
            <begin position="253"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="region of interest" description="RNA binding; important for wobble base 34 recognition" evidence="4">
        <location>
            <begin position="277"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="92"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4">
        <location>
            <position position="272"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="146"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="195"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="222"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="310"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="312"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="315"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="341"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC93643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="377" mass="42301" checksum="8785865C9250E73A" modified="2018-07-18" version="1">MLDFKLIKKDPNSAARRGQVTVNHGVIQTPIFMPVGTYGSVKAMSPLELKEIQAQIILGNTFHLWLRPGLEVVKKFGGLHKFMGWDQPILTDSGGFQVFSLGAMRKITEEGVKFASPISGERLFLSPEISMQIQKVLNSDIVMQFDECTPYEIDGRPATNDEAARSMRMSLRWAKRSMNEFNREENPNALFGIVQGGMFEHLRDESLAGLEELDFHGVAIGGLSVGEPKEDMLRVLQHVGPRLPANKPHYLMGVGTPEDLVAGVTNGIDMFDCVMPTRNARNGWLFTRFGDIKIKNARYKEDTAPLDSTCGCYACQNFSRAYLHHLHRTGEILGARLNTIHNLHYYLELMQEMRNALDVDAFSAFVVQFHADRARGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H168</accession>
    <name>A0A2S9H168_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase</fullName>
            <ecNumber evidence="2">2.7.7.70</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_1708</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + D-glycero-beta-D-manno-heptose 1-phosphate + H(+) = ADP-D-glycero-beta-D-manno-heptose + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:27465"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:59967"/>
            <dbReference type="ChEBI" id="CHEBI:61593"/>
            <dbReference type="EC" id="2.7.7.70"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.70" evidence="2"/>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93707">
        <property type="protein sequence ID" value="PRC93707"/>
        <property type="gene ID" value="S2091_1708"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033786">
        <property type="term" value="F:heptose-1-phosphate adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016773">
        <property type="term" value="F:phosphotransferase activity, alcohol group as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004821">
        <property type="entry name" value="Cyt_trans-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011914">
        <property type="entry name" value="RfaE_dom_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01467">
        <property type="entry name" value="CTP_transf_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00125">
        <property type="entry name" value="cyt_tran_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02199">
        <property type="entry name" value="rfaE_dom_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="CTP_transf_like" evidence="6">
        <location>
            <begin position="25"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC93707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="155" mass="16675" checksum="16D9B333FCC6854D" modified="2018-07-18" version="1">MFEEKITTAAALQQRISALPKPVVLTNGVFDILHRGHVTYLAQARALGASLVVAVNTDASVKRLGKGDDRPINNCEDRMAVLAALESVSLVIAFDEDTALEVVQAGRPDIYAKGGDYQMDAIPEGRAVLAYGGKVEAINFLHDRSTSKLLAKVRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1A5</accession>
    <name>A0A2S9H1A5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1647</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93646">
        <property type="protein sequence ID" value="PRC93646"/>
        <property type="gene ID" value="S2091_1647"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="313" mass="33955" checksum="DA16B38D6BB0D936" modified="2018-07-18" version="1">MTLTELKYIVAVARHRHFGHAAEACFVAQPTLSVAIKKLEDELGVILFERGGSEITTTPIGAQIVAQAERVLEQTAAIKEIAKQNNDPLAGVFRLGVIYTIGPYLLPTLVKGMIAHAPQMPLVLQENFTTRLLELLRQGELDAAIVALPLPENGFMTLPVYDEPFVVAVPNQHAWVERTGINADELKSETMLLLGNGHCFRDQVLEVCPEMARFATSDDGIARTFEGSSLETIRHMVASGIGITVLPKASAPNPTSADGMLHHLPFNEPIPMRQVALVWRKSFTRGAAISALQQVILNCDLPGVAMLPDAVAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1H6</accession>
    <name>A0A2S9H1H6_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 6">Lactoylglutathione lyase</fullName>
            <ecNumber evidence="4 6">4.4.1.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Glyoxalase I</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_1441</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>(R)-S-lactoylglutathione = glutathione + methylglyoxal</text>
            <dbReference type="Rhea" id="RHEA:19069"/>
            <dbReference type="ChEBI" id="CHEBI:17158"/>
            <dbReference type="ChEBI" id="CHEBI:57474"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="EC" id="4.4.1.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Ni(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:49786"/>
        </cofactor>
        <text evidence="6">Binds 1 nickel ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 6">Secondary metabolite metabolism; methylglyoxal degradation; (R)-lactate from methylglyoxal: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 6">Belongs to the glyoxalase I family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.4.1.5" evidence="4 6"/>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93832">
        <property type="protein sequence ID" value="PRC93832"/>
        <property type="gene ID" value="S2091_1441"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00619">
        <property type="reaction ID" value="UER00675"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004462">
        <property type="term" value="F:lactoylglutathione lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004360">
        <property type="entry name" value="Glyas_Fos-R_dOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004361">
        <property type="entry name" value="Glyoxalase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018146">
        <property type="entry name" value="Glyoxalase_1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00903">
        <property type="entry name" value="Glyoxalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00068">
        <property type="entry name" value="glyox_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00934">
        <property type="entry name" value="GLYOXALASE_I_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00935">
        <property type="entry name" value="GLYOXALASE_I_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0533">Nickel</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="7">
        <location>
            <begin position="2"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC93832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="134" mass="14643" checksum="95A9FC889E05AE98" modified="2018-07-18" version="1">MRILHTMLRVGDLQRSIDFYTNVLGMKLLRVTENPEYKYTLAFVGYGTNPEHAELELTYNYGVDNYELGTAYGHIAIAVANAVEACSAAKAAGGNVTREAGPVKGGKTVIAFITDPDGYKIELIERNPDGSRID</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1I7</accession>
    <name>A0A2S9H1I7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Beta-lactamase superfamily domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1451</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93842">
        <property type="protein sequence ID" value="PRC93842"/>
        <property type="gene ID" value="S2091_1451"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070290">
        <property type="term" value="F:N-acylphosphatidylethanolamine-specific phospholipase D activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024884">
        <property type="entry name" value="NAPE-PLD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12706">
        <property type="entry name" value="Lactamase_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038896">
        <property type="entry name" value="NAPE-PLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lactamase_B" evidence="1">
        <location>
            <begin position="94"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="343" mass="38285" checksum="74AF70676EE3989F" modified="2018-07-18" version="1">MTAPLIISDNPLLMASIQRDGKFRNSRPIARSGLIKTIKLAWRFAFQKPANTTPSHAIPVQNITQAQLMAAPDQTLYRLGHSTMLLKLDNAFWLTDPVFSERASPFSMLGPKRFHQPPISIADLPPIKGVILSHDHYDHLDYHAILALADKVEHFLAPTGVGRRLIDWGIPAHKVQELGWWSETTIGKIRFVATPARHFSGRSLTDSNQTLWASWVILTPELRLFFSGDSGYFDGFKSIGDTYGPFDLTMIETGAYDAEWPDVHMQPTETLQAHQDLRGRWLLPVHNGTFDLALHAWDDPFDKITQLAASKGISISTPQMGEALAINAPSAGSRWWVNGYAAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1K7</accession>
    <name>A0A2S9H1K7_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">S2091_1483</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93874">
        <property type="protein sequence ID" value="PRC93874"/>
        <property type="gene ID" value="S2091_1483"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036641">
        <property type="entry name" value="HPT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008207">
        <property type="entry name" value="Sig_transdc_His_kin_Hpt_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47226">
        <property type="entry name" value="SSF47226"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50894">
        <property type="entry name" value="HPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="11" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="25"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="353"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="9">
        <location>
            <begin position="459"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="7">
        <location>
            <begin position="527"/>
            <end position="749"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="8">
        <location>
            <begin position="893"/>
            <end position="1007"/>
        </location>
    </feature>
    <feature type="domain" description="HPt" evidence="10">
        <location>
            <begin position="1023"/>
            <end position="1118"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="5">
        <location>
            <position position="942"/>
        </location>
    </feature>
    <feature type="modified residue" description="Phosphohistidine" evidence="4">
        <location>
            <position position="1062"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC93874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="1118" mass="123971" checksum="8CB09A99DA11942A" modified="2018-07-18" version="1">MAVKVNSTTQKSCEIKLLRRYQRTLLLCGGALLSTALIVSACLALWMDIQDYIAEGRAMYVANKALVTQEIEKKQSAMRRGVIYSELVWSEIGSERRVDDFRHGHLLMHDNPHIVPQLLLGAVTLDNPPQRYARFLEFSRIQAYSATAGALERGESFAGYFFDPAHTFIAIASPSSTLKQLNNIPSSDVPDLIDRLAPDIGDLNDPVYLAAVRDSRRVFWQRPMPDPLSGETVLQVAVPGFDGGRPFAIFVSSISFDVLYQWLKKSSYGGNFMIIGRKGDLILSSWDHDIIDPTLTTRVLDSGAWKEKLDSSGYVYHDGIFTISEPLSDTGWVFAYAVSWRTIFTARGNFIKIYAAGTLLLLGLLWTLIGFYLKRVLNPLLLRSQRVFDSEKLNRTIIATAPNGLCLIAEGSGKVLLQNEIMKQYDGADMPLSKRFLSLWRETGIGIGAPAQPMAGPVSKHDLTVTNCDNEPRYLLVNIVRTRYLRENFLLCSFSDITERKQLESSLREARLAAESANQAKSVFLATMSHEIRTPLNGILGNLELLLHTPLTELQQDRLQTITHSSHTMLDLTNDVLDFSKIESGQMQLENIDFDLIDLVEQAMLIFVPIAEDKGLNLYYRVAPQLPRCHLGDPTRVRQIVVNLLSNAIKFTERGKVSISLDVVSPHSENVTLLVLRVADTGPGISVTQRQQLFQPFEQGNASIARQYGGSGLGLALCRRLTQLMNGEIEIESESGQGTVFAVTLPLRMAEKTSQQIAMSFSEIGVLCESSEWQVQLFPQLQAWGLTVRLLQHPGEWSKSGAPLLLFCTPRSWSVASEESAMVRGTRIIDAREDGPRLPVVQGNRVLVSCYSLEGLQRALLLAQNSSTAGSNEELTRLISLSAAVPVQQGMVRVLVVEDHLVNRELIGAQLHLLGYDVSLAADAGEALQLYSGGDYDIVLTDLSMKDVDGYMLARMLRAQGGKLPIVAITAQASSDDRQRCYGAGIDDVLLKPMSLLEIDCVIRRQLAASRTLSARPIPEQQNQTLSSHLVQALRDSSEASMEHMRAACAQQMHDVVLEQLHAIKGAFAMQQQAQVVNLCNELERDCKIVVPANFQLRLDALQALVRQVISHLEKTCD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1K9</accession>
    <name>A0A2S9H1K9_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Translocator protein BipD</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_1480</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Required for invasion of epithelial cells, as well as for survival within host cells, escape from endocytic vesicles and subsequent actin-tail formation. Probably regulates the secretion of effectors BipB and BipC and their final integration into the target cell membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the invasin protein D family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93871">
        <property type="protein sequence ID" value="PRC93871"/>
        <property type="gene ID" value="S2091_1480"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036708">
        <property type="entry name" value="BipD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009483">
        <property type="entry name" value="IpaD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06511">
        <property type="entry name" value="T3SS_TC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140693">
        <property type="entry name" value="SSF140693"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <keyword evidence="5" id="KW-0843">Virulence</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="130"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="48"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00025541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC93871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="370" mass="40248" checksum="311F70A77A4CB6E7" modified="2018-07-18" version="1">MMPITLQQRPPVMMSALDGAAVDKVRHSEQEPAAVAVENEPHVSKVSLEKIQRAMADLLELRNEQHQEYTQIEQVQKQALVPGNMSGNKLAALSEALDSAEISEKLNASKMSAAGESLLNLLSATFGNAGASGRSENAEDAPTDAPYAARSMPPSSQSGNTARGGLGDIWKQLADMIGKSEKGDLADYAAALAKYTDLYRAMTNILSKLAQWVSATDASNLKVDFGALVKELEALINEYERNPIAKGLSLQEAGALCKKLGLDPEACRVFDPITGNYRVIADLSQVKAMLSGIKDLIKTLPGNGPKYAITLVKYNAWKAGFDSQVSRLEEALQERGQKYSNNYSRFESFHKTISSIIQSMADMLRQFLQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1W0</accession>
    <name>A0A2S9H1W0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative MobA-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1120</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC93947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93947">
        <property type="protein sequence ID" value="PRC93947"/>
        <property type="gene ID" value="S2091_1120"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025877">
        <property type="entry name" value="MobA-like_NTP_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12804">
        <property type="entry name" value="NTP_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NTP_transf_3" evidence="2">
        <location>
            <begin position="8"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="194" mass="20442" checksum="6F939AD22B718DCD" modified="2018-07-18" version="1">MSQQNTVGILLAAGGGLRFDPTGVQNKLTQILPSGTPVAVQAAGNLLAVLTKVIAVVRCATLAQQLTEAGCEVHLFSQAEQGMGASLAYVIHHAAGANVDSVLVALADMPYLQTETIRKMLAALAAGTDIVQPYYQQQAGHPVGFSKRHFPALMSLTGDIGARHLLREFSVLQLPVDDAGVVRDIDFLSDLQGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2D4</accession>
    <name>A0A2S9H2D4_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">50S ribosomal protein L2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rplB</name>
        <name evidence="7" type="ORF">S2091_1312</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uL2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94139">
        <property type="protein sequence ID" value="PRC94139"/>
        <property type="gene ID" value="S2091_1312"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01320_B">
        <property type="entry name" value="Ribosomal_L2_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022666">
        <property type="entry name" value="Rbsml_prot_L2_RNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_L2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002171">
        <property type="entry name" value="Ribosomal_L2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005880">
        <property type="entry name" value="Ribosomal_L2_bac/org-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022669">
        <property type="entry name" value="Ribosomal_L2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022671">
        <property type="entry name" value="Ribosomal_L2_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014726">
        <property type="entry name" value="Ribosomal_L2_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13691">
        <property type="entry name" value="PTHR13691"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00181">
        <property type="entry name" value="Ribosomal_L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03947">
        <property type="entry name" value="Ribosomal_L2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002158">
        <property type="entry name" value="Ribosomal_L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01383">
        <property type="entry name" value="Ribosomal_L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01382">
        <property type="entry name" value="Ribosomal_L2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="SSF50104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01171">
        <property type="entry name" value="rplB_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00467">
        <property type="entry name" value="RIBOSOMAL_L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_L2_C" evidence="6">
        <location>
            <begin position="124"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="224"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="255"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC94139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="275" mass="29941" checksum="D4E13BCFAFFED19B" modified="2018-07-18" version="1">MALVKVKPTSPGRRGMVKVVTEGLHKGRPFAALLEKKSKTAGRNNNGHITTRHIGGGHKQHYRLVDFKRTKDGIPAKVERIEYDPNRTAHIALLCYADGERQYIIATKGMAAGDQVMNGAQAPIKSGNCLPIRNIPVGTTMHCVEMLPGKGAQMARTAGAGVVLMAREGVYAQVRLRSGEVRRVHIECRATVGEVGNGEHNLRKIGKAGAMRWRGVRPTVRGVVMNPVDHPHGGGEGKTAAGRHPVSPWGQQTKGKKTRRNKRTTSMIVSRRGKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2E9</accession>
    <name>A0A2S9H2E9_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 6">Transcription termination/antitermination protein NusG</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">nusG</name>
        <name evidence="9" type="ORF">S2091_1334</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 6">Participates in transcription elongation, termination and antitermination.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the NusG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94161">
        <property type="protein sequence ID" value="PRC94161"/>
        <property type="gene ID" value="S2091_1334"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006354">
        <property type="term" value="P:DNA-templated transcription, elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006353">
        <property type="term" value="P:DNA-templated transcription, termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032784">
        <property type="term" value="P:regulation of DNA-templated transcription, elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031564">
        <property type="term" value="P:transcription antitermination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.940">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00948">
        <property type="entry name" value="NusG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005824">
        <property type="entry name" value="KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006645">
        <property type="entry name" value="NGN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036735">
        <property type="entry name" value="NGN_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043425">
        <property type="entry name" value="NusG-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_L2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001062">
        <property type="entry name" value="Transcrpt_antiterm_NusG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015869">
        <property type="entry name" value="Transcrpt_antiterm_NusG_bac_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30265">
        <property type="entry name" value="PTHR30265"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30265:SF2">
        <property type="entry name" value="PTHR30265:SF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00467">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02357">
        <property type="entry name" value="NusG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00338">
        <property type="entry name" value="NUSGTNSCPFCT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00739">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00738">
        <property type="entry name" value="NGN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="SSF50104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82679">
        <property type="entry name" value="SSF82679"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00922">
        <property type="entry name" value="nusG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01014">
        <property type="entry name" value="NUSG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 5 6" id="KW-0889">Transcription antitermination</keyword>
    <keyword evidence="3 5 6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="1 5 6" id="KW-0806">Transcription termination</keyword>
    <feature type="domain" description="NGN" evidence="7">
        <location>
            <begin position="20"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="domain" description="KOW" evidence="8">
        <location>
            <begin position="141"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC94161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="195" mass="21918" checksum="35A9AF6A644E97D9" modified="2018-07-18" version="1">MSENLSSTNDPVAAVTPTGNMRWYVVHAYSGMEKSVQRALTERIERAGMQDKFGQILVPSEEVVEVKNGQKAVTERRLFPGYVFVEMEMTDDTWHLVKNTSKVTGFIGGKSNKPTPIAPHEVAKIMQQVQEGVEKPRPKVLYEIGEVIRIKDGPFTDFNGNVEEVNYEKSKVRVTVTIFGRATPVELDFSQVEKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2I7</accession>
    <name>A0A2S9H2I7_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">5-formyltetrahydrofolate cyclo-ligase</fullName>
            <ecNumber evidence="3">6.3.3.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_0815</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>(6S)-5-formyl-5,6,7,8-tetrahydrofolate + ATP = 5,10-methenyltetrahydrofolate + ADP + phosphate</text>
            <dbReference type="Rhea" id="RHEA:10488"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57455"/>
            <dbReference type="ChEBI" id="CHEBI:57457"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.3.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.3.2" evidence="3"/>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94194">
        <property type="protein sequence ID" value="PRC94194"/>
        <property type="gene ID" value="S2091_0815"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030272">
        <property type="term" value="F:5-formyltetrahydrofolate cyclo-ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002698">
        <property type="entry name" value="FTHF_cligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024185">
        <property type="entry name" value="FTHF_cligase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01812">
        <property type="entry name" value="5-FTHF_cyc-lig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006806">
        <property type="entry name" value="FTHF_cligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02727">
        <property type="entry name" value="MTHFS_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="2">
        <location>
            <position position="59"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="134"/>
            <end position="142"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR006806-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC94194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="182" mass="20160" checksum="60B7A59D8944A003" modified="2018-07-18" version="1">MKIKNMNRTAQRAALIAARRSIGVQLRNKWDMQIAEQVFAWCKAHSIKTAGIYSPIQAEPCLFGVYPLLTDLGVKLALPSAPVKDHALTFSEWVPGDELMKDRYGVLVPLETAPVVQPEVLFIPCVGFTADGYRLGYGGGFYDRTLAAKPKPKAIGIAYRISLCELEIMPHDIAMDSMITDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2K3</accession>
    <name>A0A2S9H2K3_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Phospholipase C</fullName>
            <ecNumber evidence="2">3.1.4.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_1269</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial phospholipase C family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.4.3" evidence="2"/>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94096">
        <property type="protein sequence ID" value="PRC94096"/>
        <property type="gene ID" value="S2091_1269"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034480">
        <property type="term" value="F:phosphatidylcholine phospholipase C activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017767">
        <property type="entry name" value="Bact_PC-PLC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007312">
        <property type="entry name" value="Phosphoesterase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008475">
        <property type="entry name" value="PLipase_C_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31956">
        <property type="entry name" value="PTHR31956"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05506">
        <property type="entry name" value="DUF756"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04185">
        <property type="entry name" value="Phosphoesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03396">
        <property type="entry name" value="PC_PLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015783577" description="Phospholipase C" evidence="3">
        <location>
            <begin position="34"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="domain" description="DUF756" evidence="4">
        <location>
            <begin position="469"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="domain" description="DUF756" evidence="4">
        <location>
            <begin position="568"/>
            <end position="652"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF05506"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC94096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="662" mass="71211" checksum="74221AEDD3CE020C" modified="2018-07-18" version="1">MTKIRGSRRQFLTTSAATAATAFIPSVLKTAMAATPAGSSLSAVKHVVIFMQENRSFDHYYGSLQGVRGFNDRTALTLRNGNTVFKQPSGSSYEMPFHLDTTATSAQCMSDLDHSWTGTHSAWDNAKYDNWVAAKGSLTMGYYTRADIPFHYAMADAFTICDNYFCSIMGPTNPNRLYLWSGMIDPNGTGGGPITNNDEPGFSWTTYPERLQAAGVSWKVYQKTSDNFDDNALAWFTQYRNAAVGSPLYNNGMSSVPVVTGNTVSDIVAAIKNDVLNNTLPQVSWVVAPASASEHPSNPPANGADMVSQVLGALTSNPTVWASTVMFLNYDENDGYFDHIVPPVPAAGTASEFVSGVPIGLGPRVPMTVISPWSRGGYVNSQVFDHTSVIRFLETWTGVQEPNISAWRRLICGDLTSTLNFNSTTVSVPSMPNTAALAQQAATQCSTLPAPTAPLNQITPLQEFGTRLACALPYQPNGTSLVAKSTGIVWITMTNTGSQAVHHSIYANNYRSDGPWQYDVAANGSVKDYFHVQTYGGGYYDLSLYGPNGFMRRFVGNINTAAGGLLEVTSSYSFATAGNAQLLLTMVNNTTASVTFTVTSNGYRTDGPWTCVVAAGATVSSYWNVQTVTSGWYDFTATVNADSSFSRRFAGHVELGGTSITG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2L0</accession>
    <name>A0A2S9H2L0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cupin domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0843</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94222">
        <property type="protein sequence ID" value="PRC94222"/>
        <property type="gene ID" value="S2091_0843"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013096">
        <property type="entry name" value="Cupin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07883">
        <property type="entry name" value="Cupin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cupin_2" evidence="1">
        <location>
            <begin position="58"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="169" mass="18529" checksum="4968653F76BD796A" modified="2018-07-18" version="1">MSIVSKPANSMNSEGVFEPFPIADVPWEEFAKGQRFGMRFQHLSSYGGATQIGVANEVLLPGKQANPAHYHMLEEEHVFILEGALTLRLGDKAYIMSAGQYVCFPAGQKQGHALFNHTDVACRYLIIGNTQANDVAVHTETGRVAVKLMGVGYSGTATMDYWDSMNIDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2L8</accession>
    <name>A0A2S9H2L8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Bacterial extracellular solute-binding protein, family 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_0842</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94221">
        <property type="protein sequence ID" value="PRC94221"/>
        <property type="gene ID" value="S2091_0842"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001638">
        <property type="entry name" value="Solute-binding_3/MltF_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00497">
        <property type="entry name" value="SBP_bac_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00062">
        <property type="entry name" value="PBPb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015461796" evidence="2">
        <location>
            <begin position="26"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="domain" description="PBPb" evidence="3">
        <location>
            <begin position="27"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC94221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="256" mass="28553" checksum="8CBB27794A0B69C4" modified="2018-07-18" version="1">MMSQILNVVKICIICTVFSALPAQAEELVVYGGEAFQPLIYLDSEQAAGIFPALFQRLSKSTGDTYKLVLLPWKRAISESAAGKGGITSFTWTEERAKLYDFSEPVYRNTIELTVLKNKAFKFNQLTDLTGKIIGIPLGSSFGDAFDKAVADNLITSDTDPSQVSRLRKLLIGRIDVAIIGERALEQAIRSDPVLLANQNKFTVLPVPLTQDWLYLAFPKTMHKLPALQRFNQALIALKKTKEYQQIIDDNSFHSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2M6</accession>
    <name>A0A2S9H2M6_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peptide chain release factor 1</fullName>
            <shortName evidence="5">RF-1</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">prfA</name>
        <name evidence="7" type="ORF">S2091_0855</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 5">Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="5">Methylated by PrmC. Methylation increases the termination efficiency of RF1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the prokaryotic/mitochondrial release factor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94234">
        <property type="protein sequence ID" value="PRC94234"/>
        <property type="gene ID" value="S2091_0855"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016149">
        <property type="term" value="F:translation release factor activity, codon specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00093">
        <property type="entry name" value="Rel_fac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005139">
        <property type="entry name" value="PCRF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000352">
        <property type="entry name" value="Pep_chain_release_fac_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045853">
        <property type="entry name" value="Pep_chain_release_fac_I_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004373">
        <property type="entry name" value="RF-1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03462">
        <property type="entry name" value="PCRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00472">
        <property type="entry name" value="RF-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00937">
        <property type="entry name" value="PCRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75620">
        <property type="entry name" value="SSF75620"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00019">
        <property type="entry name" value="prfA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00745">
        <property type="entry name" value="RF_PROK_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5" id="KW-0488">Methylation</keyword>
    <keyword evidence="4 5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RF_PROK_I" evidence="6">
        <location>
            <begin position="224"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="modified residue" description="N5-methylglutamine" evidence="5">
        <location>
            <position position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS00745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC94234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="355" mass="39822" checksum="5B05EAABB281314F" modified="2018-07-18" version="1">MLTKLDHLAERLVEINQLLMQEGSTSNMDNYRKLNREHAELTPVVELYHRYQQTQLDIDSAQEMMSDPDMKEFAQEEIANAKAVMETLDGELQTMLLPKDPNDERNIILEIRAGTGGDESALFSGDLLRMYTRYAERNRWQVEMMSESPSDLGGYKEVIIRIAGLGAYSKLKFESGGHRVQRVPATETQGRIHTSACTVAVMPEADELTDVIINTSDLRIDTFRASGAGGQHINKTDSAVRLTHMPTGIVVECQDGRSQHQNKAQAMRVLASRIMDGQLRAKQAKEAATRKSLIGSGDRSERIRTYNFPQGRMTDHRINLTLYKLDFIMDGDLTDLTNALLAEHQAELLAQLAGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2T9</accession>
    <name>A0A2S9H2T9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative NADP-dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0920</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94299">
        <property type="protein sequence ID" value="PRC94299"/>
        <property type="gene ID" value="S2091_0920"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016628">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041694">
        <property type="entry name" value="ADH_N_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045010">
        <property type="entry name" value="MDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43205">
        <property type="entry name" value="PTHR43205"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16884">
        <property type="entry name" value="ADH_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PKS_ER" evidence="1">
        <location>
            <begin position="21"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="343" mass="36653" checksum="70D69E06C2312B59" modified="2018-07-18" version="1">MIVHPLTSREVKLARRPDETPRPEHFEIVTSPMPRPSAQEILVRNRWFRISISARLMMSAGAEDIKGIPFPPIKPGDTLADGAIGEVVSAPSESGLQPGDFVSHHCGWREYAAVPLNQCVLLPSGPVNPVAYLGHGWTAYAALTRGVQVRQGDTVFVSSGAGAIGSMAGQIARRLGAARVIGSTTSHTKAEWMKTALGYDAVIVIGSTPIAELLADAAPEGIDVYVDIVGGEHLQAAVEVARQGARFVLLGALTAELAAKGATKVAPVELDSFQLIIKGMTLRGYSADNDPDAFNEWLQHLDEWQQDNGIHLTSSKFTGIESAPQALHEACLGRLKGLVYVEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H305</accession>
    <name>A0A2S9H305_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">GGDEF: diguanylate cyclase (GGDEF) domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_0867</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94246">
        <property type="protein sequence ID" value="PRC94246"/>
        <property type="gene ID" value="S2091_0867"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041617">
        <property type="entry name" value="TPR_MalT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17874">
        <property type="entry name" value="TPR_MalT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015615403" evidence="2">
        <location>
            <begin position="31"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="439"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="3">
        <location>
            <begin position="515"/>
            <end position="653"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC94246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="699" mass="77710" checksum="0E55AC6F879042B9" modified="2018-07-18" version="1">MRIYGDNYFSSHVCLISFVLLCFWATTSYAIDANPTPVQAEINRLVDLSETQKEESLKQLIALQNQLPADAKLEDQRDALIGLIDLYIKNEQSVPARKQNADLSALGVRYHDNWSSAMALNFQAVFLQNDGKLDQAKETIEQALLLAKNVNVNKVTNRINGVAGSIYQDLGDFEAALQHQLVAMDSLEEGGRNAVLMRIVVLNDIGILYLSLKNPELALEYNAKATKLALSVDAKSKMDTLAINRGHAYGAQGKYADAMSAYKEARNYARRNSNVRSEVVAVNNLADVTYRMGHYTECLQYAKQTLLLAEILENSSDTADAHVNIGLCRMGLGEVQTGAAEVNLGIDSMRKANAKPDIEMVLGKLASAYEKAGMYREAYKAQSDQIALTTELFGKERNRTVSEMKAKYDAIQSEKQIEVLEQKTRLQSVEINNKSLQRVISILASLIAVSITLTILFLYRKVRETNHNLEQANLKLAQQSTRDPLTGLLNRRAFHEAMQFRAQITDRRTPADTSLSHALVLLDIDHFKRINDKFGHAAGDKVLIELSNRLTVVMREKDMLMRWGGEEFLIFLNHIPIVNLQQVIERILVSVGGKPVVYGKNILQVTVSAGYISLPQGAESEVDLNWEKSLNLADSALYMAKTRGRNQAIGIKKVDVPKEEFDELLQGDLENSIKQGKITIEQIAGPPQSDIVAEPGSQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H396</accession>
    <name>A0A2S9H396_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Lauroyl/myristoyl acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_1061</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94440">
        <property type="protein sequence ID" value="PRC94440"/>
        <property type="gene ID" value="S2091_1061"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009247">
        <property type="term" value="P:glycolipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd07984">
        <property type="entry name" value="LPLAT_LABLAT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004960">
        <property type="entry name" value="LipA_acyltrans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30606">
        <property type="entry name" value="PTHR30606"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03279">
        <property type="entry name" value="Lip_A_acyltrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF026649">
        <property type="entry name" value="MsbB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC94440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="287" mass="31570" checksum="4BA7FE73F0D2EBE5" modified="2018-07-18" version="1">MLVGLFRLLSFLPLPILHGIGASLGWLVYLISPSYRHRLQTNIRQAGFAEHTRSAVSEAGKNILELAFVWCAPPDKVLKTATIENWEIAQAALDAKQGVIFLTPHLGCFEIIAQAIAVRTPLTALYRPPRKQALQPLMTDARSRTNLLLAPANLTGVRSMLKALKKGGAVGLLPDQVPQQGEGIWANFFGRPAYTMTLSSKLHSMTGAPIILSYAERLSFGRGFLIRFVPFTETLTGTPEQQASAINLAMEKLIAQCPAQYFWSYNRYKTPANVAAPTTNSDNNHKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3A0</accession>
    <name>A0A2S9H3A0_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ATP-dependent protease ATPase subunit HslU</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Unfoldase HslU</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">hslU</name>
        <name evidence="8" type="ORF">S2091_1072</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the ClpX chaperone family. HslU subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94451">
        <property type="protein sequence ID" value="PRC94451"/>
        <property type="gene ID" value="S2091_1072"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009376">
        <property type="term" value="C:HslUV protease complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036402">
        <property type="term" value="F:proteasome-activating activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043335">
        <property type="term" value="P:protein unfolding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00249">
        <property type="entry name" value="HslU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019489">
        <property type="entry name" value="Clp_ATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004491">
        <property type="entry name" value="HslU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48102:SF3">
        <property type="entry name" value="PTHR48102:SF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07724">
        <property type="entry name" value="AAA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01086">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00390">
        <property type="entry name" value="hslU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 5" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="6">
        <location>
            <begin position="52"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="domain" description="ClpB_D2-small" evidence="7">
        <location>
            <begin position="339"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="21"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="63"/>
            <end position="68"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="260"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="325"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="397"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM01086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC94451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="447" mass="49622" checksum="5E8C1C82BADF7EF6" modified="2018-07-18" version="1">MNNMMSMTPQEIVSELDKHVVGQDRAKRAVAIALRNRWRRQQVAEPLRNEITPKNILMIGPTGVGKTEIARRLAKLADAPFIKIEATKFTEVGYVGRDVDTIIRDLIEIGIKQTRATEIKKVRARAEDAAEDRILDILLPPARDFGLNPPDAAPADNNTRQTLRKRLREGALNDKEIEIEVADVAPQLEIMAPPGMEEMTEQIKSMFSGVGGSRKKSRKLLIPEALKLLIEEEASKLLNEDDIKQNAIQSVEQNGIVFLDEIDKIASRSETGGAEVSRAGVQRDLLPLVEGTTVNTKYGTIKTDHILFIASGAFHLAKPSDLIPELQGRFPIRVELESLSIADFERILTGTDACLTKQYIALLATENVQIVFVDSGIKKLAEIAYSVNETTENIGARRLYTVMEKLLEEISFEADKNSGDAIEINGEYVQQRLGALAVDDDLSRYVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3A5</accession>
    <name>A0A2S9H3A5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1083</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94462">
        <property type="protein sequence ID" value="PRC94462"/>
        <property type="gene ID" value="S2091_1083"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="111" mass="11757" checksum="0BBD5366CBEB0CF7" modified="2018-07-18" version="1">MPNLTHLLIAYPALTVLLAGPMALPGTVITAPACVFTVLPVPFTVMVEPLEVMIVPDGTKTELFAGIVYELPAVSDDGAEVAELGLEPPPQADKVATKQSAKNVRRLFCML</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3F9</accession>
    <name>A0A2S9H3F9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Multicopper oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_0500</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94497">
        <property type="protein sequence ID" value="PRC94497"/>
        <property type="gene ID" value="S2091_0500"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011706">
        <property type="entry name" value="Cu-oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045087">
        <property type="entry name" value="Cu-oxidase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011707">
        <property type="entry name" value="Cu-oxidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033138">
        <property type="entry name" value="Cu_oxidase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002355">
        <property type="entry name" value="Cu_oxidase_Cu_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709">
        <property type="entry name" value="PTHR11709"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07731">
        <property type="entry name" value="Cu-oxidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07732">
        <property type="entry name" value="Cu-oxidase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="SSF49503"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00079">
        <property type="entry name" value="MULTICOPPER_OXIDASE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00080">
        <property type="entry name" value="MULTICOPPER_OXIDASE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="6">
        <location>
            <begin position="164"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="5">
        <location>
            <begin position="471"/>
            <end position="597"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF07732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC94497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="603" mass="66670" checksum="DE8D0DC95F22DC3F" modified="2018-07-18" version="1">MFGFKLDCRYLFCCTRVRCSALPFIALLFFTSLYSLSGWAGSLPQTGTPGAPLDLCPRPQAGSAVPEPEDLRSQNGVLKLDLSIHNYRQQDGSTRYCYLLPDGTQSPTLRLHPGDLLILRLKNDLVPDKSATLDLQALGKQTVCSVKPKKQINACTSGAMTTISTNLHFHGLTVPPVCHQDDVLKTAIQPSDSAFEYRFKIPRNEPPGLYWYHPHIHGFSSKQVQGGASGALIIEGIERAIPDVAGLPERVLIIRDQDLLYPDAAPSKSEPVVPKMLMDRDGDAGNNGTGFGKPAKDLSINFVPVPYPEYPPASITMKPDERQLWRVLNASSITYLNLSLLFQHSPQQLGIIAIDGVPIKTDREHTTAIEWVNHIGLPPGARVEFIMNGPPVGVPGLFVTRTVDTGPSGENDTNRALATVLAKEEAATLQSTLPTSHDPLPPSAVAWLGDVTPTRVRKLYFSEKQADPSDPNSATEFYITEDGKTPTLFDPQAGMPNIVTTQGDVEDWIIENRSTELHAFHIHQIHFLVMDWSGIPIDEPFLRDTVNIPYFKDNMLTYPSVRLRMDFRDPNTIGTFVYHCHLLEHEDGGMMGTVRVERPTKKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3K7</accession>
    <name>A0A2S9H3K7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC-type spermidine/putrescine transport system permease component II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_0568</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94565">
        <property type="protein sequence ID" value="PRC94565"/>
        <property type="gene ID" value="S2091_0568"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="57"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="107"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="134"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="195"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="239"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="61"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC94565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="276" mass="30620" checksum="FB81B0D9703F1FBB" modified="2018-07-18" version="1">MNAYRWFGRGWLSLGYLFLYIPIIMLIVYSFNNSSQDMVWKGFTLHWYSALMDDHEIIAGFFLSLKVATLSATFSVVLGTFTAYVLNNYRKFNGRALFKGMASAPLVMPEVIIGLSLLLMLVGLENAFGFPQRGLPTLVFGHTVLGVAYSTVVIESRLREMSKSLSEAAMDLGCKPYQVFGLVTLPNISQSLVSAWLLTFTLSLDDVVVSAFLTGPGYSTMPIVIFSRARLGLDPRVNTVAALTILVVTIAVVLSSLYMARKERKRQKEISAAFKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3L3</accession>
    <name>A0A2S9H3L3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Nitrogen regulatory protein PII</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_0526</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the P(II) protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94523">
        <property type="protein sequence ID" value="PRC94523"/>
        <property type="gene ID" value="S2091_0526"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030234">
        <property type="term" value="F:enzyme regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006808">
        <property type="term" value="P:regulation of nitrogen utilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002187">
        <property type="entry name" value="N-reg_PII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011322">
        <property type="entry name" value="N-reg_PII-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015867">
        <property type="entry name" value="N-reg_PII/ATP_PRibTrfase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017918">
        <property type="entry name" value="N-reg_PII_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002332">
        <property type="entry name" value="N-reg_PII_urydylation_site"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30115">
        <property type="entry name" value="PTHR30115"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00543">
        <property type="entry name" value="P-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039144">
        <property type="entry name" value="GlnB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00340">
        <property type="entry name" value="PIIGLNB"/>
    </dbReference>
    <dbReference type="SMART" id="SM00938">
        <property type="entry name" value="P-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54913">
        <property type="entry name" value="SSF54913"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00638">
        <property type="entry name" value="PII_GLNB_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51343">
        <property type="entry name" value="PII_GLNB_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00496">
        <property type="entry name" value="PII_GLNB_UMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="modified residue" description="O-UMP-tyrosine" evidence="2">
        <location>
            <position position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR039144-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR602187-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC94523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="112" mass="12204" checksum="73E066B15831BE5A" modified="2018-07-18" version="1">MKLITAIIKPFKLDEVREALSGIGVQGITVTEVKGFGRQKGHTELYRGAEYVVDFLPKTKIEAAVDDALVERVVEAIETAARTGKIGDGKIFVYALEQVVRIRTGETGNDAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3M9</accession>
    <name>A0A2S9H3M9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">BlaR1 peptidase M56</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0597</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94594">
        <property type="protein sequence ID" value="PRC94594"/>
        <property type="gene ID" value="S2091_0597"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008756">
        <property type="entry name" value="Peptidase_M56"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05569">
        <property type="entry name" value="Peptidase_M56"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="101"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="303"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M56" evidence="2">
        <location>
            <begin position="102"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="528" mass="58747" checksum="2FBA84013B35D7D5" modified="2018-07-18" version="1">MNAQFGFVSAVAHALLHSLWQVALLALLAEVSFSQLRHRSAMARHAVGMGWLVMMLLVPLLTFTQFWQSPSLATDGVPIMPIPFTPGVEHFTPASQPWLDWVLVATTELWLLGAALMLVLQLGGWRMIKHMEQQPYVDLPPEWRNRIERLRGALGISRAVAIRMASKISSPCTAHVLRPIIWLPLTLLTHLPPDQIEALLAHELAHIRRLDWCWNALQCVIESVLFFHPAMWWLSRRIREEREHACDDLAVAVCGNPIALAEALAGLQRQRLVTPRFALAAQGGSLMKRISHLLSGPPARQNWRIPVVLLLLLCSGTLLAMQVEPPRHLLLNLRIDASSNGALTPGNFREYTADYVFDKQRYYRISMDQQGQVREVYKEDGRVKPVDNAVHMWAKELQSMATPPEPPELPALAEVGAPPIPPTPPVPPEFQYSDELKDLFKSMQADGRLAAMVGAPISVERGSFHGSFHTWGARDFHLWGIDDPVGGKAGFSINFVGPKGRAKVAYAGKTQAGVWQASKLEISPLVAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3Y2</accession>
    <name>A0A2S9H3Y2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative virion core protein (Lumpy skin disease virus)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0697</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94694">
        <property type="protein sequence ID" value="PRC94694"/>
        <property type="gene ID" value="S2091_0697"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03408">
        <property type="entry name" value="SPFH_like_u1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036013">
        <property type="entry name" value="Band_7/SPFH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033880">
        <property type="entry name" value="SPFH_YdjI"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13421">
        <property type="entry name" value="Band_7_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117892">
        <property type="entry name" value="SSF117892"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Band_7_1" evidence="1">
        <location>
            <begin position="27"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13421"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="344" mass="37473" checksum="269F2CF4242E317E" modified="2018-07-18" version="1">MSLGSFIKKQFIDVLQWNEDTEGVLAWRFPMQDFEIQNGGMLTVRESQIAVFVNEGQVADVFGPGNHKLTTQTLPVLTYLKNWDKLFESPFKSDVYFFSTRIQTGRKWGTTQPITIRDKDFDMVRIRAFGMYSYRVTDAKKFFTEISGTREQYTRDEVEDQLRGITLATMANSIGTANVPFLDMAANQTLMAQHVKGDLAQAFEKYGLGLDEFNVTSVSLPDELQAALDERISAGMKGGLSAEKMGGFTQFQVASSIPLAAQNEGGLAGLGAGLASGVAFGQVMAQGLAAPATPSTNPSAPPVAPAEDAIEVRLEKLKGLLDKALISASDYETAKAELLKKLIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H433</accession>
    <name>A0A2S9H433_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0742</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94739">
        <property type="protein sequence ID" value="PRC94739"/>
        <property type="gene ID" value="S2091_0742"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="79"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="107" mass="11296" checksum="46C8F6F779E9DBD5" modified="2018-07-18" version="1">MKLPPYQLSKREGQPWRIPLNVSLLIFQSWVACALFALAMIGISNALGCSVNEGGTSPCLIAGMDIQILILTPTLLAVFGAPLFLIGISGSAAVALTTFLFVSMKGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H469</accession>
    <name>A0A2S9H469_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glyoxalase-like domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0754</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94751">
        <property type="protein sequence ID" value="PRC94751"/>
        <property type="gene ID" value="S2091_0754"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004360">
        <property type="entry name" value="Glyas_Fos-R_dOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026275">
        <property type="entry name" value="Glyoxalase/dOase/EhpR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00903">
        <property type="entry name" value="Glyoxalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039020">
        <property type="entry name" value="EhpR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="3"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="123" mass="13243" checksum="31BEEC04EBBC3B87" modified="2018-07-18" version="1">MFNPNFILLYVANPLASADFYAKLLGKPAIEKSPTFAMFALESGVKLGLWAKHTVEPAVTASQGGSELAFAVANNDIVTAQHNDWKERGLVIAQTPTAMDFGYTFVALDPDGNRLRVFAPSAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4E1</accession>
    <name>A0A2S9H4E1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative amidohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_0049</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94854">
        <property type="protein sequence ID" value="PRC94854"/>
        <property type="gene ID" value="S2091_0049"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016811">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006807">
        <property type="term" value="P:nitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07572">
        <property type="entry name" value="nit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003010">
        <property type="entry name" value="C-N_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036526">
        <property type="entry name" value="C-N_Hydrolase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045254">
        <property type="entry name" value="Nit1/2_C-N_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001110">
        <property type="entry name" value="UPF0012_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00795">
        <property type="entry name" value="CN_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56317">
        <property type="entry name" value="SSF56317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50263">
        <property type="entry name" value="CN_HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01227">
        <property type="entry name" value="UPF0012"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CN hydrolase" evidence="3">
        <location>
            <begin position="2"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC94854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="270" mass="29687" checksum="1EDA50C9D7B9D5D8" modified="2018-07-18" version="1">MMKIAAIQMTSGPLLHDNINTATRLIDEAVAAGAKLVLLPEYWPVMGMHEQDKTRLAQSPDAALMTEFMAEQARSHGIYLIGGTIPCPSPEVDKVYNSSLVFDPQGHQVARYDKIHLFGFTKGAESYQESLSILAGTKPVSVEAKVGADTYKIGLSICYDLRFPELYRAFGACDLIVVPAAFTYTTGSVHWEVLLRARAIENQCYVLASGQVGRHPNGRHTWGHSMLIDPWGKIVSVLPDSEGVVAGELDTQLIQEVRRNLPALQHRMLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4V0</accession>
    <name>A0A2S9H4V0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0210</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95015">
        <property type="protein sequence ID" value="PRC95015"/>
        <property type="gene ID" value="S2091_0210"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018750">
        <property type="entry name" value="DUF2306_membrane"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10067">
        <property type="entry name" value="DUF2306"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="64"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="96"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="129"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC95015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="176" mass="19247" checksum="7DBCA2BA69978F3B" modified="2018-07-18" version="1">MALDIGIIGWVHTIACIIALISGFILLWKLKGGDVHKRLGGNYVIASVIANITALAIYKIGGFTLFHILALATLISLIIAFVSARWKIPGQFWLRVHLTAIIFSYYQLVGGLINEVFLRVPGLKEKTAAISNFQGLALVFFLMLIAYFGGKTSRSLIQATSVRPRANINHPKISGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4V3</accession>
    <name>A0A2S9H4V3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acetyltransferase (GNAT) domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0204</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95009">
        <property type="protein sequence ID" value="PRC95009"/>
        <property type="gene ID" value="S2091_0204"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13508">
        <property type="entry name" value="Acetyltransf_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="8"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC95009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="166" mass="19007" checksum="949C0E5885F28797" modified="2018-07-18" version="1">MQITHPNTALRPINDTDMAFLKQVYGSTREEELRQTNWNDAQKTSFIDMQFQAQHSAYSAYPNAEFFLILHDTQQVGRVYLQHRPDAILIIDLALLTQFRGRGIGSGILQSIFTEAQQLGKSVLIHVEKFNPALLLYQRLGFKLIADKGVYLLLEWQSPELVSTIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4W0</accession>
    <name>A0A2S9H4W0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC-type sugar transport systems permease component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_0168</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94973">
        <property type="protein sequence ID" value="PRC94973"/>
        <property type="gene ID" value="S2091_0168"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008643">
        <property type="term" value="P:carbohydrate transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="45"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="97"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="131"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="180"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="226"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="286"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="94"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC94973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="319" mass="34970" checksum="DF5640B367153021" modified="2018-07-18" version="1">MSEIYPGIASSAQQASNIKHPIPLQRRFQTFADIWLPRLVLSPTILLSLIFVYGFIGFTAYLSLTPSRLMPNYTYTGFGQYAALFDIDRWWVSATNLGIFGGLFILICLGVGLLLAIFLDQKIRAEGALRAIYLYPMALSFIVTGAAWKWILNPGLGLEKMVHAWGFPNFSMDWLVNSDMAIYTVVIAGVWQSSGFVMALFLAGLRGVDDSIIKAAMVDGASLPTIYRRIVIPALRPVFFSVLLVLSHIAIKSFDLVMALTAGGPGTSTDVPAIFMYQFSFTRGQLGLGAASAMMMLATVLAVLVPLIYLETKEARRAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H502</accession>
    <name>A0A2S9H502_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Response regulator receiver domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0265</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95070">
        <property type="protein sequence ID" value="PRC95070"/>
        <property type="gene ID" value="S2091_0265"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="5"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC95070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="121" mass="13422" checksum="B119B35DED0A05F3" modified="2018-07-18" version="1">MAIQKILVVDDSPTERYFLTDILAKNGFSVSTAENGEEALLKIKADKPHLILMDVVMPGQNGFQITRAIARDAETQDVPVIICTSKNQETDRIWGLRQGARDYLVKPIDPQELLAKIASLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H525</accession>
    <name>A0A2S9H525_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Outer membrane protein (Porin)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_0287</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95092">
        <property type="protein sequence ID" value="PRC95092"/>
        <property type="gene ID" value="S2091_0287"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046930">
        <property type="term" value="C:pore complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015288">
        <property type="term" value="F:porin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006811">
        <property type="term" value="P:ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00342">
        <property type="entry name" value="gram_neg_porins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033900">
        <property type="entry name" value="Gram_neg_porin_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023614">
        <property type="entry name" value="Porin_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002299">
        <property type="entry name" value="Porin_Neis"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13609">
        <property type="entry name" value="Porin_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00184">
        <property type="entry name" value="NEISSPPORIN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0406">Ion transport</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0626">Porin</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1134">Transmembrane beta strand</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015652734" evidence="5">
        <location>
            <begin position="32"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="domain" description="Porin_4" evidence="6">
        <location>
            <begin position="19"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF13609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC95092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="348" mass="36946" checksum="A0B5599AAB4AB74F" modified="2018-07-18" version="1">MLLPDFFDWNMNMKKSVFATALLGTFGLASAQSTMTIYGILDAGISADNSSAAGSVAKLESGMESGSRFGFKGTEDLGNGLKALFVLEQGIALDTGTLTSGGHLFGRQALVGLGGTFGTVTMGRQYTPIFSAYGSIDPFGNNSAGDINTLFGKNSNFISKDYRMDNSVIYTAPVNLGGFNAAVAYGFGEQAGDSAAQSQVGLSLGYASGPIKAVYAYHAENNANSIVDTDTYKSHFLGATYDFNRVKVHAAFDQTTQGADHKTQSYLLGATVPLGIHSIFADVTYRDNKLLNDANASQIAIGYNHTLSKRTNLYTILGCIINDDNSKVNTQVLGKTVNKVQVGMRHVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H543</accession>
    <name>A0A2S9H543_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acid phosphatase, Burkholderia-type</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0181</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94986">
        <property type="protein sequence ID" value="PRC94986"/>
        <property type="gene ID" value="S2091_0181"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003993">
        <property type="term" value="F:acid phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017768">
        <property type="entry name" value="AcpA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007312">
        <property type="entry name" value="Phosphoesterase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31956">
        <property type="entry name" value="PTHR31956"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04185">
        <property type="entry name" value="Phosphoesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03397">
        <property type="entry name" value="acid_phos_Burk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="551" mass="59530" checksum="9726EDB4F2851C55" modified="2018-07-18" version="1">MQAKDNDQINQPDDPPTNPARRRLLQAGAAAGVLGSVPLAVNSKPVPSGSSLNAKLKDNIKNVVVIFLENRSFTNLFANFPGVSKPLSEVPAAAYAQLDRNGQVLTQLPKIWGGIVPQEQTLGGKQYQITESKITGLPNAPFALTDGDGKPLPEGLITRDLAHLFYQNQMQINGGKNDQFVAWGNSGAMVMGHYGETQKNLGLWQVAKEYTLCDNFFMAAFGGSFLNHQFLISGRAPEYFNAASSPAKDKIVVTEDGPTGTRLAIAKDNPASAVDGPPKFVRDGSISPDGYAVNTMAPPFQPSYIKPAESGDQTLADAQNPSTLPPQTFRTIGDVLSQKGVSWAWYGGAWQAALDAKGGGPRPNFQYHHQPFNYFQKFAPGSKERAEHLRDGGVGDSPISNKFLTDVVAGKLPAVTFYKPQGNLNLHAGYSDVESGDQHVVNVLEHLKHSPQWKNMLVVITFDENGGWWDHVAPPKGDRWGPGSRVPAIIVSPFAKKGNVDHSFYDTTSIMRFISRLYDLPLLEGLAVRNAAFAERGALPPGDLTGALSFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H552</accession>
    <name>A0A2S9H552_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Gram-negative porin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_0191</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94996">
        <property type="protein sequence ID" value="PRC94996"/>
        <property type="gene ID" value="S2091_0191"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046930">
        <property type="term" value="C:pore complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015288">
        <property type="term" value="F:porin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034220">
        <property type="term" value="P:ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00342">
        <property type="entry name" value="gram_neg_porins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033900">
        <property type="entry name" value="Gram_neg_porin_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023614">
        <property type="entry name" value="Porin_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001702">
        <property type="entry name" value="Porin_Gram-ve"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002299">
        <property type="entry name" value="Porin_Neis"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13609">
        <property type="entry name" value="Porin_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00182">
        <property type="entry name" value="ECOLNEIPORIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00184">
        <property type="entry name" value="NEISSPPORIN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0626">Porin</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1134">Transmembrane beta strand</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015392798" evidence="7">
        <location>
            <begin position="30"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="domain" description="Porin_4" evidence="8">
        <location>
            <begin position="17"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF13609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC94996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="363" mass="38398" checksum="A9D97F69012799E9" modified="2018-07-18" version="1">MNNTAFKESCLQFLLLTTVLGACSGQVKAQSNVTLYGRVDAEVNYQSNQNTGRIDSNGVAITGSQWSAPGNEWGTSFFGFKGAEDLGGGMKALFTLESGFATGNGVVNGGSALWSRRAFVGLSGDYGTLKLGRDLTLPSDIVWSLDPTGQQAMGTATLAKGRNWPQTSNQVQYITPDMNGFSAVGMYGFGEVAGSTQDSSSNGIELGYNKDGLELKVMYDVAYDPSGQLSTLFQYSKELTAGGTLTLDKWKLFAGCQTQSAPDMLASYGNPDKATQFWLGANYKITPALTLIPAAFHVNLNQSTGSANLIMLGANYSLSKRTLLFASIGSLHNSALTSFAIEVGNSAVGVNQSAFYTGISQSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5A1</accession>
    <name>A0A2S9H5A1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Prc: C-terminal processing peptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_0357</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the peptidase S41A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95162">
        <property type="protein sequence ID" value="PRC95162"/>
        <property type="gene ID" value="S2091_0357"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07560">
        <property type="entry name" value="Peptidase_S41_CPP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004447">
        <property type="entry name" value="Peptidase_S41A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005151">
        <property type="entry name" value="Tail-specific_protease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020992">
        <property type="entry name" value="Tail_Prtase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040573">
        <property type="entry name" value="TSP_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11818">
        <property type="entry name" value="DUF3340"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00595">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03572">
        <property type="entry name" value="Peptidase_S41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17804">
        <property type="entry name" value="TSP_NTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00245">
        <property type="entry name" value="TSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="SSF50156"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00225">
        <property type="entry name" value="prc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0720">Serine protease</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015506395" evidence="5">
        <location>
            <begin position="20"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="domain" description="PDZ" evidence="6">
        <location>
            <begin position="229"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="614"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="614"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="667"/>
            <end position="685"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC95162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="706" mass="78519" checksum="D7F6D9FFC5189DB6" modified="2018-07-18" version="1">MKNKILWILLALFSTTLNATQENGALSPLPQQARAAHFAARVLAQENYEHLPFDEKLSSAIFDNYIKELDGEKLIFLQSDIDQFANARPQFGLALLNEDLSIPFAIFNLRQQRIAEHLNYSRSLLAHGFNFKEKESLQPDRKYATWPKSKEEMNDLWRKRAKNDWLRLKLAGKDDKGIVDILDKRYDNSLKSILRIKGDDVFQIFMDAYATANDPHTNYFGVRAAESFDISMKLSLTGIGAELQYKDEYITIRHLVPGSPAELSGKLKAGDRILAVGQGEKGPTSDVMGMSIFDAVALIRGAEDSVVRLDVLPAEAGPDGTHQLVTLIRKKITLENQSAKKSIIDVQDGATTRHIGVISLPGFYRDFFAQKNGDNDFKSAARDVSLILEEFKKEQVDGVLLDLRNNGGGSVEEAIELTGLFVEKGPVMQQLDSKDRVKVDKISAAGTPVWKGPFGVLINRASASASEIFAAAIQDYGRGIVIGETSFGKGSTQAVVNLDRLVKNDKPDFGELKMTVTKWFRINGDAIQLRGVTPDIILPMFTDAENFGESSFDNALPWGKIPATDYKSSSDLVHIVPTLIADHNARVSKDKAFQDLQEDITEFKTQRKKNLISLNEDERRKEREAQKAKVKLRKNELAKTKSGNSSEKDAAGTDASTRQDDGLLATERNFTNDKDADKKDSADKDVLLKEAAHIIDDEASLLRAKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5D6</accession>
    <name>A0A2S9H5D6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative thioesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0346</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95151">
        <property type="protein sequence ID" value="PRC95151"/>
        <property type="gene ID" value="S2091_0346"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC95151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="144" mass="16567" checksum="15D03302890F29F8" modified="2018-07-18" version="1">MRRQAESSRWWAETEIKVQFFDLDPMQIVWHGNYVKYLEIVRCELLNKIGYNYSEMLASGFSWPIIDMQLRYVGAAVFNQRLKLRAEIVEWESRLKINYLISDAATGKRLTRASTTQVAVNIASGEMCFVSPPALLTKLGVDPC</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GS68</accession>
    <name>A0A2S9GS68_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">RHS repeat-associated core domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4729</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000056">
        <property type="protein sequence ID" value="PRC90562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90562">
        <property type="protein sequence ID" value="PRC90562"/>
        <property type="gene ID" value="S2091_4729"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001826">
        <property type="entry name" value="RHS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022385">
        <property type="entry name" value="Rhs_assc_core"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00394">
        <property type="entry name" value="RHSPROTEIN"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03696">
        <property type="entry name" value="Rhs_assc_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC90562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="226" mass="22131" checksum="C839F8C3BEEB6A5F" modified="2018-07-18" version="1">MYGKSASGSSLDAETNLHQNYYRNYDPNSGRYIESDPLGLGGGISTYGYVGGNPLSFDDPFGLCITQAQADAISAGLGGFVGGYIGSGGKWQVGVLTGVVGGIAGYISSDTGISGNVVAGTAGGIGYAAKGGGGVPGIIGNGIAGFLINGLASTATQTGTENTSGGALGGTVGGLITGLLMKAPIGNNVNPILGAGYGFLGGLAAGLTQDFINDLLKSQICTCDKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSA2</accession>
    <name>A0A2S9GSA2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transposase DDE domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_4727</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000055">
        <property type="protein sequence ID" value="PRC90568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90568">
        <property type="protein sequence ID" value="PRC90568"/>
        <property type="gene ID" value="S2091_4727"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025668">
        <property type="entry name" value="Tnp_DDE_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13751">
        <property type="entry name" value="DDE_Tnp_1_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tnp_DDE_dom" evidence="2">
        <location>
            <begin position="182"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="52"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC90568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="311" mass="35461" checksum="0EA441315FE2F7E4" modified="2018-07-18" version="1">MKEIESSINQYLTELDTADRHEPEIKQARTERLHQKIAKLQTQMKQLAHIKEQLDDTPDNQLSQTDPDARSMRTRGSGIVGYNVQTAVDTKHHLIVAHEVSNDGNDRDQLFNMATQARDAMGVKELTAIGDRGYYKNTEILACDQANIKAIVAKSVTSNATSDGRFGKDDFIYDASNDVYRCPAGQQLIKRMTVVERGITSHKYWASGCKTCPLKSQCTPSPQRRVSRWENEAVLDEMQRRLDHFPQAMRIRRETVEHTFGTIKFWMGTQHFLMRTLKHVATEMSLHVLAYNMKRMIKIIGIAPLMQAVQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSD8</accession>
    <name>A0A2S9GSD8_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Probable membrane transporter protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_4642</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000041">
        <property type="protein sequence ID" value="PRC90634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90634">
        <property type="protein sequence ID" value="PRC90634"/>
        <property type="gene ID" value="S2091_4642"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002781">
        <property type="entry name" value="TM_pro_TauE-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01925">
        <property type="entry name" value="TauE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="40"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="105"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="172"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="208"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="236"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="266"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC90634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="289" mass="31183" checksum="CBFF5AC5A99EA623" modified="2018-07-18" version="1">MRQSNILFLHILLESYSTTYPQCFLPNIYSNFFLNSMTEYLILCIAAFSAGLIDAVVGGGGLINVPAIFSTFPNGIPATLLGTNKLGGIWGTAAAAVNYARVVKIIWNVAISVACAVLVFSFIGAYTVTRIPSDFLRKCLPLILVMVAIYTFKRKNFGQSHTPFHTDTKERTLAFSTGAGIGFYDGFFGPGTGSFLIFVFVRFFGFDFLTASAISKIVNVACNGAALLLFGISGHVMWAVGFTMAVFGVAGSLVGTRLAIKNGSGFVRKLFLCIVVVLIIKTSYDAFLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSG2</accession>
    <name>A0A2S9GSG2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative FAD-dependent dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4634</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000040">
        <property type="protein sequence ID" value="PRC90651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90651">
        <property type="protein sequence ID" value="PRC90651"/>
        <property type="gene ID" value="S2091_4634"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028348">
        <property type="entry name" value="FAD-binding_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42842">
        <property type="entry name" value="PTHR42842"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038984">
        <property type="entry name" value="FAD_binding_protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC90651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="533" mass="58304" checksum="5B6D49AE2D023F13" modified="2018-07-18" version="1">MLRLTDIQLPLDHPDTAIRLAILKKLGILDEELLSFEVFRRSYDARKKSAISLIYTLDIVTTKNEQLITQFHGDKNVTRTPDTNYQFVAHATNQDFLRPVVIGTGPCGLFAGLLLAQMGFRPIILERGKAVRERTQDTWGLWRKRELNPESNVQFGEGGAGTFSDGKLYSQIKDPKHYGRKVLTEFVKAGAPEEIMYVSKPHIGTFRLVKMVEDMRATIIALGGEVRFSQKVVDILREDEAIRGVILENGEQIRTNHVVLAIGHSARDTFEMLCERGVYIEAKPFSVGFRVEHPQSIIDRCRFGPSAGHPILGAADYKLVHHASNGRSVYSFCMCPGGTVVAATSEPNRIVTNGMSQYSRNERNANSAIVVGITPEDYPGHPLAGIPFQRALESHAYILGGSNYNAPGQLVGDFIAGRASSEFGAVQPSYKPGVQLGDLSSALPDYAISAMREALPAFDKQIRGFAMNDAVLTGVETRTSSPIRIKRNDIDLQSLNTRGLFPAGEGAGYAGGILSAAVDGIRVAEAVALSMTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSQ5</accession>
    <name>A0A2S9GSQ5_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">YceI domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_4566</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000037">
        <property type="protein sequence ID" value="PRC90740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90740">
        <property type="protein sequence ID" value="PRC90740"/>
        <property type="gene ID" value="S2091_4566"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007372">
        <property type="entry name" value="Lipid/polyisoprenoid-bd_YceI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036761">
        <property type="entry name" value="TTHA0802/YceI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04264">
        <property type="entry name" value="YceI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00867">
        <property type="entry name" value="YceI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101874">
        <property type="entry name" value="SSF101874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015615397" description="YceI domain-containing protein" evidence="1">
        <location>
            <begin position="24"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="domain" description="YceI" evidence="2">
        <location>
            <begin position="27"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC90740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="192" mass="20753" checksum="DD09D2619A4712C5" modified="2018-07-18" version="1">MKSLTQLTLASALIASLSGTAFAAPETFVIDSTHTMPRFSYSHFGYSTQLSRFDKTTGTIVLDKEAKTGSVDVTIDMKSVDTGYPLFNGHIQGADFFDTENYPTATFKSTKVNFDGDKPSTVEGNLTIKGVTKPVTLKLSSFQMMPHPMLKKDAIGANASTTVKRTDFNAGKYAPYVGDDVTIDIAVEAINQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSU8</accession>
    <name>A0A2S9GSU8_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ribonuclease VapC</fullName>
            <shortName evidence="5">RNase VapC</shortName>
            <ecNumber evidence="5">3.1.-.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Toxin VapC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">vapC</name>
        <name evidence="7" type="ORF">S2091_4514</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Toxic component of a toxin-antitoxin (TA) system. An RNase.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the PINc/VapC protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="5"/>
    <dbReference type="EMBL" id="PUGF01000036">
        <property type="protein sequence ID" value="PRC90766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90766">
        <property type="protein sequence ID" value="PRC90766"/>
        <property type="gene ID" value="S2091_4514"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004540">
        <property type="term" value="F:ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090729">
        <property type="term" value="F:toxin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00265">
        <property type="entry name" value="VapC_Nob1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002716">
        <property type="entry name" value="PIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022907">
        <property type="entry name" value="VapC_family"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01850">
        <property type="entry name" value="PIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="SSF88723"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 5" id="KW-0540">Nuclease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0800">Toxin</keyword>
    <keyword evidence="1 5" id="KW-1277">Toxin-antitoxin system</keyword>
    <feature type="domain" description="PINc" evidence="6">
        <location>
            <begin position="5"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="7"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="99"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC90766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="134" mass="15059" checksum="D0326A9268F123F6" modified="2018-07-18" version="1">MMLHMLDTDTASYLIKGKSPSIEVKLAALVPSMICISVMTRAELLYGLKRLPTDHRLHLAVRQFLKIVRVLSWDAEAADWYAEIRHQLIGSGQPIGELDMMIAAHSLSAGAVLVTNNIRHYQRIEAPLILDNWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSV3</accession>
    <name>A0A2S9GSV3_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Flagellar motor switch protein FliG</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">S2091_4526</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Bacterial flagellum basal body</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the FliG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000036">
        <property type="protein sequence ID" value="PRC90778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90778">
        <property type="protein sequence ID" value="PRC90778"/>
        <property type="gene ID" value="S2091_4526"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009425">
        <property type="term" value="C:bacterial-type flagellum basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003774">
        <property type="term" value="F:cytoskeletal motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071973">
        <property type="term" value="P:bacterial-type flagellum-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000090">
        <property type="entry name" value="Flg_Motor_Flig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023087">
        <property type="entry name" value="Flg_Motor_Flig_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011002">
        <property type="entry name" value="FliG_a-hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032779">
        <property type="entry name" value="FliG_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028263">
        <property type="entry name" value="FliG_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30534">
        <property type="entry name" value="PTHR30534"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01706">
        <property type="entry name" value="FliG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14841">
        <property type="entry name" value="FliG_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14842">
        <property type="entry name" value="FliG_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003161">
        <property type="entry name" value="FliG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00954">
        <property type="entry name" value="FLGMOTORFLIG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48029">
        <property type="entry name" value="SSF48029"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00207">
        <property type="entry name" value="fliG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0975">Bacterial flagellum</keyword>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="13" id="KW-0966">Cell projection</keyword>
    <keyword evidence="6" id="KW-0145">Chemotaxis</keyword>
    <keyword evidence="13" id="KW-0969">Cilium</keyword>
    <keyword evidence="7" id="KW-0283">Flagellar rotation</keyword>
    <keyword evidence="13" id="KW-0282">Flagellum</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FliG_N" evidence="12">
        <location>
            <begin position="5"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="domain" description="FliG_M" evidence="11">
        <location>
            <begin position="115"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="domain" description="FliG_C" evidence="10">
        <location>
            <begin position="216"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF14841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF14842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PRC90778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="332" mass="36456" checksum="79F80C5888C49645" modified="2018-07-18" version="1">MSDVGLQKAAILMLALGEDCASEVMRHLGPREVQKLGISMAGMTAIPHETVAATLGEFLNDADVSSSMGIDSDDYIRNVLTKALGDDKASSLLNRILGGRDASGIESLKWMDSPSVAELIRNEHPQIIATILVHLERDQACEILTNFTERLRNDVILRIATLDGIQPAALRELNDVLTKLLTGNESLKKKTIGGVRAAAEILNFMSGEQEASVMSNLRNYDGDMAEKIMDEMFVFDNIMDIDDRGIQLLLREVQSDTLIVALKGANPEMRDKIFKNMSQRAAEMMRDDLESKGPVRLSEVEAQQKAILIIVRRLADEGQIMLGSKGGEDAFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSZ1</accession>
    <name>A0A2S9GSZ1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4484</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000035">
        <property type="protein sequence ID" value="PRC90821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90821">
        <property type="protein sequence ID" value="PRC90821"/>
        <property type="gene ID" value="S2091_4484"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="72" mass="7578" checksum="A6A05C1C27C740ED" modified="2018-07-18" version="1">MNLVKMMAVALIVAGVLGLVYGGFSYTKETHDVKIGTFELSLNEKQTINIPIWAGVGAIAIGGFLLALGGKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GT10</accession>
    <name>A0A2S9GT10_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phage portal protein, PBSX family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4443</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the phage portal family. PBSX subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000034">
        <property type="protein sequence ID" value="PRC90862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90862">
        <property type="protein sequence ID" value="PRC90862"/>
        <property type="gene ID" value="S2091_4443"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030935">
        <property type="entry name" value="PBSX_Proteobac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006944">
        <property type="entry name" value="Phage/GTA_portal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006430">
        <property type="entry name" value="Phage_portal_PBSX"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04860">
        <property type="entry name" value="Phage_portal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018494">
        <property type="entry name" value="PBSX_VPQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01540">
        <property type="entry name" value="portal_PBSX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="344" mass="38579" checksum="A4FC417333E06F79" modified="2018-07-18" version="1">MSESIPPDTVPATTNNTRMEAFTFGDPTPVLEHSEMLDSFECWLNGRWYEPPISFPGLAKSLNASVHHSSAIYFKTNILTSTFVPNKFLTRDAFKRFALDFLIFGNAYLEKRTSRSGLLLSLAPALAKFVRRGKELNSYYFVTGWQQEHEFAAGSIFHLIDPDINQEVYGVPQYLSALQSAWLNEAATLFRRKYYKNGSHAGFIFYMTDAAQNQTDVDSLRKAMRESKGPGNFRNLFMYAPNGKKDGIQILPVSDVAAKDEFFNIKGVTRDDVLAAHRVPPQLLGIMPNNTGGFGAVEPAARVFARNELVPLQAQFRALNDWLGQDVIQFTDYELSTMPTGVTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GT14</accession>
    <name>A0A2S9GT14_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4417</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000034">
        <property type="protein sequence ID" value="PRC90836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90836">
        <property type="protein sequence ID" value="PRC90836"/>
        <property type="gene ID" value="S2091_4417"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002686">
        <property type="entry name" value="Transposase_17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036515">
        <property type="entry name" value="Transposase_17_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01797">
        <property type="entry name" value="Y1_Tnp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01321">
        <property type="entry name" value="Y1_Tnp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143422">
        <property type="entry name" value="SSF143422"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Y1_Tnp" evidence="1">
        <location>
            <begin position="9"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="177" mass="21288" checksum="D8EBE5D637DF2013" modified="2018-07-18" version="1">MSNYRRAWHKGGTYFFTVNLLQRKENDLLVRHIDFLRDAVRQTIKSHPFTIHGWVVLPDHLHCVMTLPIGDSDFALRWRLIKSRFSKTIPDKEWRSDIRKKRGERGVWQRRYWEHLIRDEKDFTAHMDYVHINPLKHGLVKQVCDWPFSTFHRLVQDGVYPIDWAGGSSEIPEYVDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GT94</accession>
    <name>A0A2S9GT94_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_4401</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000033">
        <property type="protein sequence ID" value="PRC90908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90908">
        <property type="protein sequence ID" value="PRC90908"/>
        <property type="gene ID" value="S2091_4401"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000485">
        <property type="entry name" value="AsnC-type_HTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019888">
        <property type="entry name" value="Tscrpt_reg_AsnC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019887">
        <property type="entry name" value="Tscrpt_reg_AsnC/Lrp_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01037">
        <property type="entry name" value="AsnC_trans_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00033">
        <property type="entry name" value="HTHASNC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00344">
        <property type="entry name" value="HTH_ASNC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50956">
        <property type="entry name" value="HTH_ASNC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH asnC-type" evidence="4">
        <location>
            <begin position="3"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC90908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="159" mass="18136" checksum="32FD520C6C314BF7" modified="2018-07-18" version="1">MELDKTDLAILRYLQEDGRINNSDLADKIFLSASSCLRRVRALEEAGVISSYCAVLDADSVGLEVDAFVQVTMRRDIEQWHENFSKEIQHWPEVVGSFIITGEANYLLRVRARNLKHYSTFIMDRLYKTSGVLDIRSNIVLQTLKDTHVIDSALLKSTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTC8</accession>
    <name>A0A2S9GTC8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Polysaccharide pyruvyl transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4357</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000032">
        <property type="protein sequence ID" value="PRC90956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90956">
        <property type="protein sequence ID" value="PRC90956"/>
        <property type="gene ID" value="S2091_4357"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007345">
        <property type="entry name" value="Polysacch_pyruvyl_Trfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04230">
        <property type="entry name" value="PS_pyruv_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PS_pyruv_trans" evidence="1">
        <location>
            <begin position="67"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="425" mass="47633" checksum="D833D9220D44DDDE" modified="2018-07-18" version="1">MAISNSKKMKIYLHVAIPSSKENHALPTSLKKRVKRVMRTALDWLAWGINKTFLFKCYNYTQRAYCNRGDIAIKLAIKELLQKGLHDVELDFVETEWGCLNKEILADINQNAAIFVIAGGGYWVFSKTKKLSRAFLADSPFFPKISCPIAVFGSGVNFNMPSADAVLNVHLDAELQKVFMEFDQRVNFLAVRDQLTVDFFRSLGMKKTTLLCDPAVFLEPAAMQARPSGTPISIGINLAFHGPFAAQIFKKNILFYIEFLKSVQKKFHAKFMYFVHSDEELLIVQLLRFSGIKLEVVDQPAAELTGAYAQLDVLLCQMMHSNILSFNVGVPALNIAYDSKNFGFNQLIGMEDYCVSAHNLDAQVLLEKMSDLIANRAALALKLASKKKELSFPMEAFLHEVRELALSPQSVEIESPLPSLCVKSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTI1</accession>
    <name>A0A2S9GTI1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Prepilin-type N-terminal cleavage/methylation domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4316</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000031">
        <property type="protein sequence ID" value="PRC91020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91020">
        <property type="protein sequence ID" value="PRC91020"/>
        <property type="gene ID" value="S2091_4316"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043683">
        <property type="term" value="P:type IV pilus assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032092">
        <property type="entry name" value="PilW"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16074">
        <property type="entry name" value="PilW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="265" mass="27834" checksum="F56F2CDDCD2E0084" modified="2018-07-18" version="1">MTNLTFSPHASMAPGLRKNGFSLIELMVAVTIGLFITLGLSQVFLSMYSTSKSQNSLAQFQDNERLALVMLTNTVELAGYFASPLTTTLASLQATAYTNTDGSVFSNGIGVVGKNTYPTTGTSDSLNVYYQSSGNDGVINCQGQPATTGTSTVFINSFTINSKNELVCAVTPIISGTTGSTTSALVLASNVASMTILYGVDVLGTGTTSSYLTATALNNSSPSLWPNVRTVQITLNFYVANVFNLATAPTTTTAWVQTINIMRAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTN4</accession>
    <name>A0A2S9GTN4_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 10 14">Catalase</fullName>
            <ecNumber evidence="3 10 14">1.11.1.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">S2091_4261</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Serves to protect cells from the toxic effects of hydrogen peroxide.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 14">
            <text>2 H2O2 = 2 H2O + O2</text>
            <dbReference type="Rhea" id="RHEA:20309"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="EC" id="1.11.1.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 10 12">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the catalase family. HPII subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.6" evidence="3 10 14"/>
    <dbReference type="EMBL" id="PUGF01000030">
        <property type="protein sequence ID" value="PRC91073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91073">
        <property type="protein sequence ID" value="PRC91073"/>
        <property type="gene ID" value="S2091_4261"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004096">
        <property type="term" value="F:catalase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042744">
        <property type="term" value="P:hydrogen peroxide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03132">
        <property type="entry name" value="GATase1_catalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1370.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018028">
        <property type="entry name" value="Catalase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024708">
        <property type="entry name" value="Catalase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024712">
        <property type="entry name" value="Catalase_clade2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043156">
        <property type="entry name" value="Catalase_clade2_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011614">
        <property type="entry name" value="Catalase_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002226">
        <property type="entry name" value="Catalase_haem_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010582">
        <property type="entry name" value="Catalase_immune_responsive"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041399">
        <property type="entry name" value="Catalase_large_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020835">
        <property type="entry name" value="Catalase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42821">
        <property type="entry name" value="PTHR42821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00199">
        <property type="entry name" value="Catalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06628">
        <property type="entry name" value="Catalase-rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18011">
        <property type="entry name" value="Catalase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038927">
        <property type="entry name" value="Catalase_clade2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00067">
        <property type="entry name" value="CATALASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01060">
        <property type="entry name" value="Catalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56634">
        <property type="entry name" value="SSF56634"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00437">
        <property type="entry name" value="CATALASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00438">
        <property type="entry name" value="CATALASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51402">
        <property type="entry name" value="CATALASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10 13" id="KW-0349">Heme</keyword>
    <keyword evidence="9 10 14" id="KW-0376">Hydrogen peroxide</keyword>
    <keyword evidence="8 10 12" id="KW-0408">Iron</keyword>
    <keyword evidence="6 10 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 10 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4 10 14" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Catalase" evidence="15">
        <location>
            <begin position="44"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="91"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="164"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="88"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="128"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="177"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="374"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="12">
        <location>
            <position position="378"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="385"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR038927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR038927-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR038927-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR038927-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU000498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM01060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="PRC91073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="703" mass="77750" checksum="0161D3436706CE3F" modified="2018-07-18" version="1">MSDIKVGIPPAKLVLVTVPTAIPSTLGRGDELHQSIVSDYPALTTNQGVIIADNQNSLRATAHGPTLLEDFILREKITHFDHERIPERIVHARGTGVHGFFELTESLSQYTTAKVLTEVGEKTPLFARFSTVAGGAGSADTPRDVRGFAVKFYTKQGNWDLVGNNIPVFFIQDALKFPDLIHAVKMEPDRGFPQAATGHDTFWDYISLTPEAMHMVMWIMSDRTLPRSLRMMEGFGIHSFRLINAEYESTFVKFHWRPKLGLQSTLWDEAVKISGADADFHRRDMFEAISNGNFPEWELAVQLFTQKQADSFPFDHLDATKLIPEEMIPLQVIGRMVLNRWPDNFFAETEQVAFCPSHIVPGIDFSNDPLLQGRLFSYLDTQLSRLGSANFNQIPINAPKCPFANQQRDGHMQMTQPVGRVAYEPNTLATDSPREKIAGGFRSAIVVDSGEKSRIRPESFADHYSQARQFYRSQTEYEQAHIASALVFELSKLEHPHIRESIVAHLRNIDEQLAGRVGHGLGMKQLPEAALKAVAIQDMMLSPSLQIIGKMKATLEGRVVGVLIMRGSDSTHINAIRHAIITAGAAIKFISPIIGEVELSDGSLQVIDGQLAGTPSVIYDAIAVILTEISVSTLCKEATALEFVRDAFCHLKAICVDEGGNTLLQKAGIEKTSGVIGITALGDFIEAAATRQWEREASIRTLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTU2</accession>
    <name>A0A2S9GTU2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative NTP binding protein (Contains STAS domain)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4131</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000028">
        <property type="protein sequence ID" value="PRC91130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91130">
        <property type="protein sequence ID" value="PRC91130"/>
        <property type="gene ID" value="S2091_4131"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13466">
        <property type="entry name" value="STAS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SSF52091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50801">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="STAS" evidence="1">
        <location>
            <begin position="1"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="109" mass="11914" checksum="7F35D76DF096F00D" modified="2018-07-18" version="1">MTAETITATATLRIEGEMDIYRAAELKNTLLAALDQTKQLELDLASVSELDTAGVQVLIMIKKQALANGRTLRLIAHSRAVIEVLKLFNLITYFDDSPLISASPATGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTW1</accession>
    <name>A0A2S9GTW1_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">FGE-sulfatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_4142</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000028">
        <property type="protein sequence ID" value="PRC91141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91141">
        <property type="protein sequence ID" value="PRC91141"/>
        <property type="gene ID" value="S2091_4142"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005532">
        <property type="entry name" value="SUMF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042095">
        <property type="entry name" value="SUMF_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03781">
        <property type="entry name" value="FGE-sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="SSF56436"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FGE-sulfatase" evidence="2">
        <location>
            <begin position="34"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="293"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="369" mass="40430" checksum="D5EF46FFE6AF9FF0" modified="2018-07-18" version="1">MKNSLLLKILLGLLAISSMIIVTSLSHGRKPPPTGMVWIPAGDFLMGSASKLAKANEQPVFKARVSGFWMDSCDVTNAQFSAFVRATGYITTAERKPDWESLRVQLPAGTPKPDDAVLVAGAMVFTGTSKPILLNDWSAWWTYVAGANWKHPNGPASDLTGKNNYPVVQVSWLDAQAYAKWVGKRLATEVEWEYAARGGIEQADYAWGNELKPAGKTMTNIFPNQGKFPVIDVATEAHTTTQIGTQAVKSYPANGYGLYDMTGNVWQWTADYYRADRFQQLKGLKNEFGVVQNPPGPAESFDPEDSNAPANAPKRVIRGGSFLCDESYCQSYRPSARRGADPANPMSHIGFRLVLSAENQQESIKIATQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GU99</accession>
    <name>A0A2S9GU99_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">S2091_4021</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="PUGF01000026">
        <property type="protein sequence ID" value="PRC91236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91236">
        <property type="protein sequence ID" value="PRC91236"/>
        <property type="gene ID" value="S2091_4021"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902531">
        <property type="term" value="P:regulation of intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024478">
        <property type="entry name" value="HlyB_4HB_MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12729">
        <property type="entry name" value="4HB_MCP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13185">
        <property type="entry name" value="GAF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3 6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="196"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="9">
        <location>
            <begin position="589"/>
            <end position="809"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="10">
        <location>
            <begin position="849"/>
            <end position="962"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="10">
        <location>
            <begin position="1127"/>
            <end position="1243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="507"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="6">
        <location>
            <position position="898"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="6">
        <location>
            <position position="1176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC91236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="1247" mass="136025" checksum="16F12496A9EB28A3" modified="2018-07-18" version="1">MRLTVTQRMVFLIGTAIVGIAIMVGIGQYMMEKVYDSANNANVNAVPSLLVLGELRKNFDQTRMLVYRHILSYDDAKMAAMEVSLTAERQNVVESIQKYETNGCLGVNCFADDKDKSYLDQEKVLWAKFNAQIDAILVESRKGERGMAKAREGIESTLGLTEDISMLIDQHFAYNAEVARKFSVEAAATKSRALNLMLVLGILAAASIGLLGTFIARTILRLLGGEPEEAAAIAGRLALGDVSSTIDVIPGDTTSLMAKIKVLIETMRRIANRADAVGLGNLTDEVEILSGQDKLGKAINNMVTVLRSAKVMDDRRNWISDGNSQLSAALTGDFTLQQIADSAISVLGSYLGAGRGVLYVLRPDGSSLDLLGSYMYTERVNLGTSFKIGEGAIGQVAREKKPIILTTIAVDAAPIITGTTCAPPLYTYTYPLLRDNLLLGAVELGSFERFDEVKLEFLHGAVEVIASSLHIAEQRGQISKLLSVAEQAERDVRAQNENLQEINAQMEEQQQQLQQQSGELQLSNSQMEEQQQQLQQQSEELQQTNAQMEEQQKLLEKNNAELRHSQSDIDEKAKQLEQSNQYKSEFLANMSHELRTPLNAIILLSKMMADNHEGRLGATEIKRAEVIHRSGEDLLHLINDVLDLSKVDAGHMDLNFVMTSSASMTMELKDLFGSTAQSRGLEFIVQDQLQSGFISDPGKISQILRNLLSNAFKFTKEGSVSLVLERSPSEYLPLRIKVIDSGIGIPKNKLGTIFEAFRQVDGSTSREFGGTGLGLTISLRFAELLGGTIKVQSVEGKGSEFVLCLPDIPPELSARQSENEQLTAAAKGNEFGARLVSDDRDQLTAGDKVILLIDDDREFCSAIVDINHRLGYKTIVANCGADGVAFARKYKPAGILLDLGLPDINGIELLDNIKASSDLAMIPVYIVSAKDRDAALGRSNIVGYLQKPVVSNQIAEAEALLLAAIANVSDAGVLIVAGRDKSRNASCDDGSGAVLNMLKSTPNIGQRELREVSLGAELPAALEALSWGAVVIDLTQLSIKEGLSVAKTVRANNSVTALLFCGVDHLNDEEEASLRIYTDCIIVNTPKSEQRLLENIERFLRTVPLKDDANVARINDSFKGARLTGKSIMVVDDDPRNLFVITAALEQEGARVISAINGLWALELLKKEKVNLMITDIMMPEMDGYQTITAVRANPAFASIPIIALTAKAMPQDRENILEIGADDYLSKPVDYDVLNNMAALWCSKKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUD5</accession>
    <name>A0A2S9GUD5_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">UDP-N-acetylmuramate--L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptandioate ligase</fullName>
            <ecNumber evidence="6">6.3.2.45</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Murein peptide ligase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">mpl</name>
        <name evidence="10" type="ORF">S2091_3890</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate by linking it to UDP-N-acetylmuramate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>ATP + L-alanyl-gamma-D-glutamyl-meso-diaminoheptanedioate + UDP-N-acetyl-alpha-D-muramate = ADP + H(+) + phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptanedioate</text>
            <dbReference type="Rhea" id="RHEA:29563"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61401"/>
            <dbReference type="ChEBI" id="CHEBI:70757"/>
            <dbReference type="ChEBI" id="CHEBI:83905"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.45"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="6">Cell wall biogenesis; peptidoglycan recycling.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the MurCDEF family. Mpl subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.45" evidence="6"/>
    <dbReference type="EMBL" id="PUGF01000024">
        <property type="protein sequence ID" value="PRC91345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91345">
        <property type="protein sequence ID" value="PRC91345"/>
        <property type="gene ID" value="S2091_3890"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00544"/>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106418">
        <property type="term" value="F:UDP-N-acetylmuramate-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptanedioate ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009254">
        <property type="term" value="P:peptidoglycan turnover"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02020">
        <property type="entry name" value="Mpl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005757">
        <property type="entry name" value="Mpl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036565">
        <property type="entry name" value="Mur-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004101">
        <property type="entry name" value="Mur_ligase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036615">
        <property type="entry name" value="Mur_ligase_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013221">
        <property type="entry name" value="Mur_ligase_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000713">
        <property type="entry name" value="Mur_ligase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01225">
        <property type="entry name" value="Mur_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02875">
        <property type="entry name" value="Mur_ligase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08245">
        <property type="entry name" value="Mur_ligase_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53244">
        <property type="entry name" value="SSF53244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53623">
        <property type="entry name" value="SSF53623"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01081">
        <property type="entry name" value="mpl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 6" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1 6" id="KW-0132">Cell division</keyword>
    <keyword evidence="2 6" id="KW-0133">Cell shape</keyword>
    <keyword evidence="5 6" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="6 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3 6" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mur_ligase" evidence="7">
        <location>
            <begin position="2"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="domain" description="Mur_ligase_M" evidence="9">
        <location>
            <begin position="108"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="domain" description="Mur_ligase_C" evidence="8">
        <location>
            <begin position="310"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="110"/>
            <end position="116"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC91345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="468" mass="50774" checksum="5B832B2FAAB33976" modified="2018-07-18" version="1">MRIHILGICGTFMGGLAVLAQQAGHTVTGCDANVYPPMSTQLREQGITLIEGYDPEQINQDIDLYVVGNAIVRGNPLMEAILNRGLPYCSGPAWMGEHILTGKWVLAVAGTHGKTTTSAMLAWILQEAGYEPGFLIGGVPNNFGISARLGADATKPASNFFVIEADEYDSAFFDKRSKFVHYRAKTAILNNLEYDHADIFPDLAAIETQFHHLVRTVPGIGQLVVNGQEPALQRVLQRGCWSEKTFFGVADGWHFVGDEVLFKERAYGPLVWQIQGEHNRQNALAAIAAAHHVGIAPELALEALSHFENVKRRMEVRGVVNNITVYDDFAHHPTAITTTIAGLRKKVGTARILAVLEPRSNTMKLGSMKAALPGSLEQADLVFAYGALQGRDTLGWDLAESLAPLGERVTTFSDLSALQNALLAQARPGDHILIMSNGGFGGIHQKLVDSLATNLSVPFNHPTQAELT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUF9</accession>
    <name>A0A2S9GUF9_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Shikimate dehydrogenase (NADP(+))</fullName>
            <shortName evidence="8">SDH</shortName>
            <ecNumber evidence="3 8">1.1.1.25</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">aroE</name>
        <name evidence="12" type="ORF">S2091_3895</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>NADP(+) + shikimate = 3-dehydroshikimate + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:17737"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16630"/>
            <dbReference type="ChEBI" id="CHEBI:36208"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.25"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 4/7.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the shikimate dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.25" evidence="3 8"/>
    <dbReference type="EMBL" id="PUGF01000024">
        <property type="protein sequence ID" value="PRC91350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91350">
        <property type="protein sequence ID" value="PRC91350"/>
        <property type="gene ID" value="S2091_3895"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00053">
        <property type="reaction ID" value="UER00087"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004764">
        <property type="term" value="F:shikimate 3-dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:cellular amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009423">
        <property type="term" value="P:chorismate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019632">
        <property type="term" value="P:shikimate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00222">
        <property type="entry name" value="Shikimate_DH_AroE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminiacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041121">
        <property type="entry name" value="SDH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011342">
        <property type="entry name" value="Shikimate_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013708">
        <property type="entry name" value="Shikimate_DH-bd_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022893">
        <property type="entry name" value="Shikimate_DH_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006151">
        <property type="entry name" value="Shikm_DH/Glu-tRNA_Rdtase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21089">
        <property type="entry name" value="PTHR21089"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18317">
        <property type="entry name" value="SDH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01488">
        <property type="entry name" value="Shikimate_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08501">
        <property type="entry name" value="Shikimate_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="SSF53223"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00507">
        <property type="entry name" value="aroE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7 8" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="5 8" id="KW-0521">NADP</keyword>
    <keyword evidence="6 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Shikimate_dh_N" evidence="10">
        <location>
            <begin position="14"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="domain" description="Shikimate_DH" evidence="9">
        <location>
            <begin position="124"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="domain" description="SDH_C" evidence="11">
        <location>
            <begin position="244"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Shikimate binding" evidence="8">
        <location>
            <begin position="22"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="73"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="69"/>
        </location>
        <ligand>
            <name>shikimate</name>
            <dbReference type="ChEBI" id="CHEBI:36208"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="94"/>
        </location>
        <ligand>
            <name>shikimate</name>
            <dbReference type="ChEBI" id="CHEBI:36208"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="109"/>
        </location>
        <ligand>
            <name>shikimate</name>
            <dbReference type="ChEBI" id="CHEBI:36208"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="134"/>
            <end position="138"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="221"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="223"/>
        </location>
        <ligand>
            <name>shikimate</name>
            <dbReference type="ChEBI" id="CHEBI:36208"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="244"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="251"/>
        </location>
        <ligand>
            <name>shikimate</name>
            <dbReference type="ChEBI" id="CHEBI:36208"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004871"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF08501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF18317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PRC91350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="278" mass="29793" checksum="D955A41EE39FF347" modified="2018-07-18" version="1">MQNKASQPLDQYAVIGNPVAHSKSPLLHAAFAAQCQQAICYRALLAPPDSFAATVKQFINDGGRGANVTLPFKLEAFNLCTALTPRAQAAGAVNTMCFEGQKIIGDNTDGCGLVSDIVRNAGVTLQGKRILLLGAGGAARGAILPLLECQPAELIIANRSIEKAQQLAEQFSSFGQISSSEFAQIKGQFDVIINATSASIAAQIPPIPDTAYNSNSLAYDMMYSDQPTVFMQHAAKHQAQTRDGWGMLVEQAAEAFYVWRGMRPDTSELLTRNMSRAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUK6</accession>
    <name>A0A2S9GUK6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">CNP1-like family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3933</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000024">
        <property type="protein sequence ID" value="PRC91388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91388">
        <property type="protein sequence ID" value="PRC91388"/>
        <property type="gene ID" value="S2091_3933"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014861">
        <property type="entry name" value="Uncharacterised_CNP1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08750">
        <property type="entry name" value="CNP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015741079" evidence="1">
        <location>
            <begin position="40"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="domain" description="CNP1" evidence="2">
        <location>
            <begin position="50"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="184" mass="20589" checksum="731CA7724197167A" modified="2018-07-18" version="1">MARMKQFKKPRNQEKISMNKTKRAIFTLLFLSLMNAAVAQEKQETHDAPAPPNLPSVAQRYIDFYSSLQLDFAIDPDSITIQPGAQKEVRYTLKATSKQGAINISYEGISCDNRQKIIYAVGRSDGSWSRARSPEWAAIYTTGLNLQHANLANGYFCSGNALSGDLKSILKRFETKQPLDAIVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUW4</accession>
    <name>A0A2S9GUW4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uracil DNA glycosylase superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3787</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000022">
        <property type="protein sequence ID" value="PRC91509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91509">
        <property type="protein sequence ID" value="PRC91509"/>
        <property type="gene ID" value="S2091_3787"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036895">
        <property type="entry name" value="Uracil-DNA_glycosylase-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52141">
        <property type="entry name" value="SSF52141"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="187" mass="19982" checksum="E8B1228FC74FD2A8" modified="2018-07-18" version="1">MLLSRLNEMSVGPLWVLRNQPVAQLETQAEFQSEIQSKTQSQIQTDACPVCGQAWLQSTLEGSSIVVVLAAPITDAAQQKLLDNCLQAAGWHAESSCFTLHVSCTSSPDASLMALQAQIAAQTPELIVVFGSTAATMINAEFSSGQIAQYANTRLIVTHHPAEMIANPSLKAQVWADLCLAKFGIVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GV42</accession>
    <name>A0A2S9GV42_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fructose-26-bisphosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3804</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000022">
        <property type="protein sequence ID" value="PRC91526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91526">
        <property type="protein sequence ID" value="PRC91526"/>
        <property type="gene ID" value="S2091_3804"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="SSF53254"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0312">Gluconeogenesis</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="189" mass="21190" checksum="ACC7481FAB7E7E75" modified="2018-07-18" version="1">MRIYLVRHPQPEIGKEFCYGSTDLVVDPHELEKVLASLMVHLPKDALLFSSPLQRCAGLAQALAEHMTTLIKFDARLVEMNFGTWELRAWNDIPRAEIDAWAEDVVNYQPGGGECVLQMAQRVASFYQELCLHQQDSIVICHAGTIRLLLACHRGLTPLQMADFAANNSHQIGYGEIVTLACTVKPVRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GV95</accession>
    <name>A0A2S9GV95_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Anaerobic dehydrogenases typically selenocysteine-containing</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_3746</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000021">
        <property type="protein sequence ID" value="PRC91630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91630">
        <property type="protein sequence ID" value="PRC91630"/>
        <property type="gene ID" value="S2091_3746"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043546">
        <property type="term" value="F:molybdopterin cofactor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02786">
        <property type="entry name" value="MopB_CT_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009010">
        <property type="entry name" value="Asp_de-COase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006657">
        <property type="entry name" value="MoPterin_dinucl-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006656">
        <property type="entry name" value="Mopterin_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006963">
        <property type="entry name" value="Mopterin_OxRdtase_4Fe-4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006655">
        <property type="entry name" value="Mopterin_OxRdtase_prok_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037920">
        <property type="entry name" value="YoaE_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04879">
        <property type="entry name" value="Molybdop_Fe4S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00384">
        <property type="entry name" value="Molybdopterin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01568">
        <property type="entry name" value="Molydop_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00926">
        <property type="entry name" value="Molybdop_Fe4S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50692">
        <property type="entry name" value="SSF50692"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51669">
        <property type="entry name" value="4FE4S_MOW_BIS_MGD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00490">
        <property type="entry name" value="MOLYBDOPTERIN_PROK_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="3 5" id="KW-0408">Iron</keyword>
    <keyword evidence="4 5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4Fe-4S Mo/W bis-MGD-type" evidence="6">
        <location>
            <begin position="3"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="10"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="14"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="18"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="46"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC91630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="694" mass="75648" checksum="16EFA341C3AF5296" modified="2018-07-18" version="1">MSTTIVRGVCPHDCPDTCALLVTVSDGVATEVRGDPDHPTTAGVLCTKVARYTERTYHPDRLLYPQKRVGKKGEGKFVRISWDEALETIAQNLTNIAANNPQAIVPYSYAGTMGLIQGEAMAHRFFHQIGASLLDRTICATAGATGYKYTIGASIGTDLEQVQHAKLILIWGSNPIVSNLHFWMRAQEAKRAGAKLIAIDPYRSLTAEKCHQHIALMPGTDAALALGLMHVLIKEELIDRDYIAKYTLGFDELAKRAEQWPPERTAATCGISVDEVVQLARAYGECCRNGDAALIRLNYGVQRVHGGGMAVRNITCLPALTGAWRQAAGGAMLSLSGGFPKNNAAMQRPDLIPIDVIPRTINMSTIGDDLLSPASPEFGPKIEAVIVYNSNPVAVAPDSEKVVQGFAREDLFTVVLEHFQTDTADYADILLPATTQLEHVDVHGAYGHYYMMANNAAIAPLGEAKPNSEFFRLLAQKMGYTDPCFSQTDDQIAAQAFRTDDVKAMHFDWDALKQSGWKKLNLPAAPFAEGGFLTPSGKCEFYSNQMLHAGLDPLPTFIAPYESVASNRELAQHYPLAMISPPARNFMNSTFVNVKSLRDTEGEPHLDMHPQDAAPRAIETGAMVRIFNQRGSMQARVRVTEKARVGVVVGLSIWWKKLAGDGQNANAVTSQKLTDMGGGATFYDVLVEVEKLSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVI6</accession>
    <name>A0A2S9GVI6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PRC-barrel domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3492</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000019">
        <property type="protein sequence ID" value="PRC91737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91737">
        <property type="protein sequence ID" value="PRC91737"/>
        <property type="gene ID" value="S2091_3492"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027275">
        <property type="entry name" value="PRC-brl_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011033">
        <property type="entry name" value="PRC_barrel-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05239">
        <property type="entry name" value="PRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50346">
        <property type="entry name" value="SSF50346"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PRC" evidence="1">
        <location>
            <begin position="13"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="122" mass="13596" checksum="D865D081594F8F04" modified="2018-07-18" version="1">MNHLHGFLNSPIKASSIIGTDVVDPKNESLGDIKEIVIDPSSGRVAYAVVSFGGFLGMGEKLFAIPFGSFKYQFDGNNYVLDVPKDVLKAAPGFDADHWPSMADEQWNRDVHAYYDRPPFWM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVN7</accession>
    <name>A0A2S9GVN7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Bacterial Ig-like domain (Group 2)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3537</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000019">
        <property type="protein sequence ID" value="PRC91782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91782">
        <property type="protein sequence ID" value="PRC91782"/>
        <property type="gene ID" value="S2091_3537"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003343">
        <property type="entry name" value="Big_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008964">
        <property type="entry name" value="Invasin/intimin_cell_adhesion"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02368">
        <property type="entry name" value="Big_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00635">
        <property type="entry name" value="BID_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49373">
        <property type="entry name" value="SSF49373"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015721021" evidence="1">
        <location>
            <begin position="28"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="domain" description="BIG2" evidence="2">
        <location>
            <begin position="50"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="domain" description="BIG2" evidence="2">
        <location>
            <begin position="135"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="domain" description="BIG2" evidence="2">
        <location>
            <begin position="227"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="domain" description="BIG2" evidence="2">
        <location>
            <begin position="409"/>
            <end position="493"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="496" mass="49447" checksum="906E5D9043F0F6D9" modified="2018-07-18" version="1">MRNYINNKLIIFNLKCCLTLFFIFVMAACGGGGSSNSSSPAQSNATATPTLQSISVTPNLSSMAAGLTLQYTATGNYSDGTSQVIQSPSWNSSAPSVATISATGLITSTQAGSSTITASANGMNGSTTLTVTAATLQSITVTSSSSSVAAGLTVQFIATGQYSDGTSQVIQSPTWSSSLIANATISSTGLATTLLPGNTVITASSNGVTGSSNGVSGSVHLTITAAILQSIAVTASSISIPLTFTEQFLAKGHYSDGSTQELPSAIWSSSTNTVATVSSTGMVTSTQSGSTTISALANGITGSLAISVSTATPSSISIVENYGTSSYLPQASIPTTLYLGSVIQLTPLVLYTDGSSMILSLPVSNTSVGSVATIGPTGVLTPVAPGTAVVSVSFSGFTTSITFTVSSATLTSIAISPSSFSISPSSTQTLTATATYSDSTSQVIQEQAVQPIIWSSSANNVVTVSQGVVNWISAGNAVITATFGGKSGTASVTSTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVY1</accession>
    <name>A0A2S9GVY1_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Lysine--tRNA ligase</fullName>
            <ecNumber evidence="8">6.1.1.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Lysyl-tRNA synthetase</fullName>
            <shortName evidence="8">LysRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">lysS</name>
        <name evidence="11" type="ORF">S2091_3430</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8 9">
            <text>ATP + L-lysine + tRNA(Lys) = AMP + diphosphate + L-lysyl-tRNA(Lys)</text>
            <dbReference type="Rhea" id="RHEA:20792"/>
            <dbReference type="Rhea" id="RHEA-COMP:9696"/>
            <dbReference type="Rhea" id="RHEA-COMP:9697"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32551"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78529"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8 9">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="8 9">Binds 3 Mg(2+) ions per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.6" evidence="8"/>
    <dbReference type="EMBL" id="PUGF01000018">
        <property type="protein sequence ID" value="PRC91874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91874">
        <property type="protein sequence ID" value="PRC91874"/>
        <property type="gene ID" value="S2091_3430"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004824">
        <property type="term" value="F:lysine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006430">
        <property type="term" value="P:lysyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00775">
        <property type="entry name" value="LysRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04322">
        <property type="entry name" value="LysRS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00252">
        <property type="entry name" value="Lys_tRNA_synth_class2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004364">
        <property type="entry name" value="Aa-tRNA-synt_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002313">
        <property type="entry name" value="Lys-tRNA-ligase_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044136">
        <property type="entry name" value="Lys-tRNA-ligase_II_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018149">
        <property type="entry name" value="Lys-tRNA-synth_II_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004365">
        <property type="entry name" value="NA-bd_OB_tRNA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00152">
        <property type="entry name" value="tRNA-synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01336">
        <property type="entry name" value="tRNA_anti-codon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00982">
        <property type="entry name" value="TRNASYNTHLYS"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00499">
        <property type="entry name" value="lysS_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 8 11" id="KW-0436">Ligase</keyword>
    <keyword evidence="8 9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="10">
        <location>
            <begin position="190"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="421"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="428"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00252"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC91874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="511" mass="57820" checksum="BDDE0DA022FDEB94" modified="2018-07-18" version="1">MTEPQANPAAAPAEDEHSIIAERRAKLTAIRAQGVAFPNDFRPTDKCAALQEKYGAFTREQLEEMNVTVAVGGRMMLKREAGKKAAFAVLQDASGKQADGRIQLYVTTEKTGEAEMEAFRTYDLGDILGIEGLLFKTKTDELTIKVSTLRLLTKSLRPLPDKFHGLANQEMKYRQRYVDLIMSEDTRRTFKARTAAMSSIRRFMEDNAFMEVETPMLHVIPGGAAAKPFITHHNALDMQMFLRIAPELYLKRLVVGGFERVFEVNRNFRNEGVSPRHNPEFTMMEFYAAYVDYKWLMDFTEQVIRKAAIDAHGTAVLTYQGRELDLSKPFHRLTIVGAINKYAPHYTNEQLHDIDFVKTELAKFGVKPFATSGLGALQLALFEETAEAQLWEPTYIIDYPVEVSPLARASDTQPEITERFELFMTGREIANGFSELNDSEDQAARFKAQMDAKEAGDEEAMYYDADYIRALEYGLPPTGGCGIGIDRLMMLITDSPNIRDVILFPHLRRED</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GW85</accession>
    <name>A0A2S9GW85_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">BNR/Asp-box repeat</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3329</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000017">
        <property type="protein sequence ID" value="PRC91987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91987">
        <property type="protein sequence ID" value="PRC91987"/>
        <property type="gene ID" value="S2091_3329"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002860">
        <property type="entry name" value="BNR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028203">
        <property type="entry name" value="PSII_CF48-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02012">
        <property type="entry name" value="BNR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14870">
        <property type="entry name" value="PSII_BNR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015548241" evidence="1">
        <location>
            <begin position="23"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="domain" description="PSII_BNR" evidence="2">
        <location>
            <begin position="85"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="330" mass="34676" checksum="2174E7BD31EC1B29" modified="2018-07-18" version="1">MKNQHKLILAVSGALFSVSVMASSIESPVAVNKPQLKVTAAEHFAGATSVKMLAATRAGKRIVAVGDYGVVLLSDDEGKSFHQAKSVPVSSTLTSVTFTDANNGWAVGHWGAILKTADGGQSWVLQRSDFAVDQPLFSVYFKNANEGWAVGLWSLMLHTADGGASWSVVSLPPPAGAKKADRNLYAIFGDAKSCLYATSEQGRVLHSEDAGATWEYAETGYSGSLWTGLNLADGALLVGGLRGTIYRSDDGGKSWQVSKTNLKSSVTNMTQRADKSIVAVGLDGLNMISVDGGVSFVGKQRQDRAALTAVIETQTPSGMQLFSSLGPVGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWB1</accession>
    <name>A0A2S9GWB1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">MatE: MATE efflux family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3342</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000017">
        <property type="protein sequence ID" value="PRC92000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92000">
        <property type="protein sequence ID" value="PRC92000"/>
        <property type="gene ID" value="S2091_3342"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042910">
        <property type="term" value="F:xenobiotic transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002528">
        <property type="entry name" value="MATE_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01554">
        <property type="entry name" value="MatE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006603">
        <property type="entry name" value="DinF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00797">
        <property type="entry name" value="matE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="46"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="95"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="136"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="164"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="191"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="239"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="281"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="320"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="358"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="386"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="417"/>
            <end position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="469" mass="50508" checksum="F828557476588AB3" modified="2018-07-18" version="1">MIKDLTQGSIRRHLITMSIPIGIGMFVQTLYFMVDLYFVGRLGDAALAGVSAAGTIMYIVMALTQMLGVGTVALMARAIGAHDKVDSNLIFNQSLLMSGLCAVVILFTGLVLTPYYFHALGADPQTTEMGVSYLRWYAPGLALQFILNAIGSALRAGGIVKPGMLVQIVTVLINIVLAPVLIAGWGTGYPLGVMGAGLASSIAIAIGVVMLFVYFVKQERFVRFQRNQMHPQWGVWRRILNIGFPAGAEFACFFVFMAVIYSIISHFGPAAMAGFGVGSRLMQAIFLPGMAIAFAVPAIAGQNMGAKAMGRVKETMRQAIYLEVGVMVFLTLVCKFQPSWLVGTFARDPQSALVAAEFLHIISWNFVATGLIFVCSGFFQALGNTWPSLLSTGTRLFLFAVPAYWLSLRPEFTLHQLWYLSVATVACQAVMSLCLLRWQWKKSMAGVASGSAAAAAESGNSVGLNLSAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWB6</accession>
    <name>A0A2S9GWB6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Oxidoreductase FAD-binding domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_3355</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000017">
        <property type="protein sequence ID" value="PRC92013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92013">
        <property type="protein sequence ID" value="PRC92013"/>
        <property type="gene ID" value="S2091_3355"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00207">
        <property type="entry name" value="fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006058">
        <property type="entry name" value="2Fe2S_fd_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008333">
        <property type="entry name" value="Cbr1-like_FAD-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001709">
        <property type="entry name" value="Flavoprot_Pyr_Nucl_cyt_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00970">
        <property type="entry name" value="FAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00111">
        <property type="entry name" value="Fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00371">
        <property type="entry name" value="FPNCR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="SSF52343"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="SSF54292"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="SSF63380"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00197">
        <property type="entry name" value="2FE2S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="5">
        <location>
            <begin position="3"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="6">
        <location>
            <begin position="99"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC92013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="339" mass="37404" checksum="7A384681E8DE83CE" modified="2018-07-18" version="1">MTFQVTVSPSGRQFECGADETVLAAALRVGLVLPHGCKNGACGACKGRILSGQTVLNKHQEKTLTPAEEQQGLSLFCCAKPQSDVTIEAREVEAGEFASKKLPTRIAKIEKLSHDVMLVCLQLPATEKFVYHAGQYIEFLLRDGKRRSYSMANAAHTSDQISLHIRHMPGGLFTDQVFSTLKERDILRIEGPQGTFYLREDSDKPMVLLASGTGFAPIKAIIEYVVEQKITRPMTLYWGGRRPADLYMHQLCLDWAANIPNFSYVPVVSDATPEDNWIGRNGFVHRAVLDDFSDLSGVQVYACGAPIVVDSAKRDFVALAKLPVEEFYADSFISEADLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWD5</accession>
    <name>A0A2S9GWD5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3350</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000017">
        <property type="protein sequence ID" value="PRC92008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92008">
        <property type="protein sequence ID" value="PRC92008"/>
        <property type="gene ID" value="S2091_3350"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="200" mass="22648" checksum="99830D5DDE9BE308" modified="2018-07-18" version="1">MKTSIKEQIKASLKASRKQVFLRADFTHFGEYRQVTRALSSLASEGLINRVGYGIYCRKMGSDSQTNQIVGKIKSRLGKRVNRLIQLGEISIRLGQPQPPNAQVSLDAFKLRLAQEIIRQVEFSDIREKSLANLSRWKLNGVWSSAYDEWEQLMKSGSEAKIMAIMIGQDEDANRLRQSAPYTGLLDQQTVERVREATTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWV7</accession>
    <name>A0A2S9GWV7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="9">TonB-dependent Receptor Plug Domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_3120</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92204">
        <property type="protein sequence ID" value="PRC92204"/>
        <property type="gene ID" value="S2091_3120"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039423">
        <property type="entry name" value="TonB-dep_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32552">
        <property type="entry name" value="PTHR32552"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="3 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0675">Receptor</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="2 5" id="KW-0798">TonB box</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015437462" evidence="6">
        <location>
            <begin position="31"/>
            <end position="779"/>
        </location>
    </feature>
    <feature type="domain" description="Plug" evidence="8">
        <location>
            <begin position="68"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="7">
        <location>
            <begin position="348"/>
            <end position="777"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC92204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="779" mass="84559" checksum="8CFB81BD9DA1454D" modified="2018-07-18" version="1">MRKIITQASFYIRSSLIFILMQIVSLPNAAAQEANNAATPTTKTVAPTSDDDGEHQVIITAQKRSEQLQNAPISVTALDSHELEKMGIESVADVARQTPGLTVVSSGPGQNILIIRGISSTAGTAGTVGYYLDDTPIAASSNASLLSLRGVIDPSIFDIDQVEVLRGPQGTLYGSSSMGGTVRYLTKQPNFDTFQFNLDTSISKTDGGGWNYTTNAVVNIPLVENTVAARIAVFDRRQDGFIDRYTINPTNYLTAPTTAPTQENANSEKTTGIRAIVKFRLEDDLTIAVSGMHQNTFLAAPFQIDVPPGNLNSLIQTRLVPEPSTQISTLANISVHKGYDQFELLSSTSYYDRSVEIAEDASKVLYYFYAPAQQSYIYPTVMTGDYINKEFTQEVRFTSDFKGPWQIIGGAYYHHVNAPLASSIPTPPGYNATFGTQIDSIFAGARQATVSETALFEETSYRISPDLTALVGLRGFRVNQTYAQQVSGEFVGDVASSVTGVSSDTGINPKFNLAWQMNKDVLLFATASKGYRPGGPNNPAPAAVCGAEVATLNLSNSALVKFGPDTLWNYELGEKSAWLDNSLLVDASVYYIDWSQVQQQIVLQCGFNITANFGTATSKGAELEMNYRPIKKLNLRLAGNFTQAKLGNDVPGTPAQKGDPLLDVPRWSASTSAEYSLLMPNGMPGFARVDYSYIGNSIALYDRTSPFYLSKGFSLVNLRVGSRKISESSHWGASLFVDNVFNKIGETGLPTAISADLPDTRRIGINRPRTIGINLKYQM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWV9</accession>
    <name>A0A2S9GWV9_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Oxoglutarate dehydrogenase (succinyl-transferring)</fullName>
            <ecNumber evidence="4">1.2.4.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_3104</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the alpha-ketoglutarate dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.4.2" evidence="4"/>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92188">
        <property type="protein sequence ID" value="PRC92188"/>
        <property type="gene ID" value="S2091_3104"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004591">
        <property type="term" value="F:oxoglutarate dehydrogenase (succinyl-transferring) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11610">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032106">
        <property type="entry name" value="2-oxogl_dehyd_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011603">
        <property type="entry name" value="2oxoglutarate_DH_E1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001017">
        <property type="entry name" value="DH_E1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031717">
        <property type="entry name" value="KGD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042179">
        <property type="entry name" value="KGD_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005475">
        <property type="entry name" value="Transketolase-like_Pyr-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23152">
        <property type="entry name" value="PTHR23152"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16078">
        <property type="entry name" value="2-oxogl_dehyd_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00676">
        <property type="entry name" value="E1_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16870">
        <property type="entry name" value="OxoGdeHyase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02779">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000157">
        <property type="entry name" value="Oxoglu_dh_E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00861">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00239">
        <property type="entry name" value="2oxo_dh_E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0786">Thiamine pyrophosphate</keyword>
    <feature type="domain" description="Transket_pyr" evidence="7">
        <location>
            <begin position="597"/>
            <end position="794"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC92188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="951" mass="105653" checksum="6D70488F4283AB32" modified="2018-07-18" version="1">MMQEYNANSYLFGGNAPYVEELYEAYLNNPGSVPDNWRSYFDAMQNVPAVDGTSKPDVAHAPVIASFAERAKSGPIRVVTASADVEMGRKRTAVQQIIAAYRFLGSSWANLDPLQRQERPNIPELDPASYGLSDADMDVKFNISNTYFGPETSSLRDLMNSLRDTYCRSIGAEFMYISNPVEKRWLQQKLESIRATPNFTVEKKKHILDRLTAAEGLERYLHTRYVGQKRFSLEGGESFIASMDEAIQRAGEFGVQEIVIGMAHRGRLNVLVNTLGKMPQDLFAEFEGKHGDDLPAGDVKYHQGFSSDISTPGGPVHLSLAFNPSHLEIVNPVVEGSVRARIERRGDGGSAQVLPIIVHGDAAFAGQGVVMETLNLAQTRGYGTGGTLHIVINNQIGFTTSDPRDARSTLYCSDVVKMIEAPVLHINADDPEAVVLATQIALDYRQEFKKDIVLDIICYRKLGHNEQDTPALTQPLMYKKIGQHPGTRKLYADKLVAQGSIGATDGDDMVKVFRDAMDAGKLTVDPVITNFKNKFAVDWIPFLNRKWTDAADTAVPMTELKRLAQRITTIPESFQPHSLVQKVLADRAAMGRGEINLDWGMGEHLAYASLVASGYSVRLTGQDAGRGTFVHRHAVLHDQKRERWDSGTYVPLQNVSDGQAPFRVIDSVLSEEAVLAFEYGYSAAEPNALTIWEAQFGDFANGAQVVIDQFISSGEVKWGRASGLTMMLPHGYEGQGPEHSSARPERFLQLCADNNMQVVQPTSAAQIFHLLRRQMIRPFRKPLVILTPKSLLRNKDAGSPLTEFAKGNFHTVIGEVDESIDPKKVKRIIACSGKIYYDLVNARKERAQTDVAIIRVEQLYPFPHKAFAAELKKFPLFNELMWTQDEPQNQGAWFQIQHNIFEALEDGQKLAYAGRPASASPAVGYYDKHYAQLKSLIDTAFSKLKGFVLTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWY1</accession>
    <name>A0A2S9GWY1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GAF domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3141</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92225">
        <property type="protein sequence ID" value="PRC92225"/>
        <property type="gene ID" value="S2091_3141"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13185">
        <property type="entry name" value="GAF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GAF" evidence="1">
        <location>
            <begin position="36"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="170" mass="18275" checksum="433A21BF05FD6B62" modified="2018-07-18" version="1">MFISPAAALKPDYSILARQVTSLLDGERDLTANAAQFSALIYEAIADLNWAGFYWVRPAKNAGNDSQRKDLLVGPFQGKVACARIAFGRGVCGTAALERRTILVADVHAFPGHIACDSASNAEIVIPVIKDGQLFGVFDIDSPSTSRFSEEDQKGLEELVAAFIAATDFH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWY9</accession>
    <name>A0A2S9GWY9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ferredoxin subunit of nitrite reductase and ring-hydroxylating dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_3151</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92235">
        <property type="protein sequence ID" value="PRC92235"/>
        <property type="gene ID" value="S2091_3151"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.102.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017941">
        <property type="entry name" value="Rieske_2Fe-2S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036922">
        <property type="entry name" value="Rieske_2Fe-2S_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00355">
        <property type="entry name" value="Rieske"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50022">
        <property type="entry name" value="SSF50022"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51296">
        <property type="entry name" value="RIESKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rieske" evidence="4">
        <location>
            <begin position="4"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC92235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="121" mass="13257" checksum="9E78527B927BE2C0" modified="2018-07-18" version="1">MTEIWVCASEDVHEGGKGIRFPVTAGNDDSTGFVVRYSGVVHGYLNRCAHVPIELDWSPGEFFEGSGLYLMCSTHGAIYEPDTGHCSGGPCKGGRLRVIKVSEKEGKVFWHPDEFVKPVRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GX09</accession>
    <name>A0A2S9GX09_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">ModA: molybdate ABC transporter, periplasmic molybdate-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_3112</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial solute-binding protein ModA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92196">
        <property type="protein sequence ID" value="PRC92196"/>
        <property type="gene ID" value="S2091_3112"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030973">
        <property type="term" value="F:molybdate ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015689">
        <property type="term" value="P:molybdate ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd13539">
        <property type="entry name" value="PBP2_AvModA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044084">
        <property type="entry name" value="AvModA-like_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005950">
        <property type="entry name" value="ModA"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004846">
        <property type="entry name" value="ModA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01256">
        <property type="entry name" value="modA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0500">Molybdenum</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="binding site" evidence="3">
        <location>
            <position position="71"/>
        </location>
        <ligand>
            <name>molybdate</name>
            <dbReference type="ChEBI" id="CHEBI:36264"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="179"/>
        </location>
        <ligand>
            <name>molybdate</name>
            <dbReference type="ChEBI" id="CHEBI:36264"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR004846-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC92196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="262" mass="27798" checksum="93E4AD00CFD28BBF" modified="2018-07-18" version="1">MLEFGALFIRSSEIAMLRKLIGCCLVLLAGSSFADEVQVAVAANFAAPMKQIALAFEQTTGHKALLSFGATGKFYAQIKNAAPFDILLAADQTTPTQLAQEQAAVAGSQFTYAIGKLVLWSAAAGLVDAQGAILKHGSFAHLALASPKQAPYGAAALETLTALNLVKELSPKFVQGESIGQTYTFVATGNAELGFVALSQVWENNQIKSGSAWIVPENLYAPLRQDAILLKHGKDNSAALALLAYLKTDAAKNIIRSYGYRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GX82</accession>
    <name>A0A2S9GX82_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Chaperonin GroEL</fullName>
            <ecNumber evidence="6">5.6.1.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">60 kDa chaperonin</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Chaperonin-60</fullName>
            <shortName evidence="6">Cpn60</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">groEL</name>
        <name evidence="6" type="synonym">groL</name>
        <name evidence="9" type="ORF">S2091_2977</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 8">Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6 8">Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the chaperonin (HSP60) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.1.7" evidence="6"/>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92318">
        <property type="protein sequence ID" value="PRC92318"/>
        <property type="gene ID" value="S2091_2977"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042026">
        <property type="term" value="P:protein refolding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03344">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.7.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00600">
        <property type="entry name" value="CH60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018370">
        <property type="entry name" value="Chaperonin_Cpn60_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001844">
        <property type="entry name" value="Cpn60/GroEL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002423">
        <property type="entry name" value="Cpn60/GroEL/TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027409">
        <property type="entry name" value="GroEL-like_apical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027413">
        <property type="entry name" value="GROEL-like_equatorial_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027410">
        <property type="entry name" value="TCP-1-like_intermed_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00118">
        <property type="entry name" value="Cpn60_TCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00298">
        <property type="entry name" value="CHAPERONIN60"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48592">
        <property type="entry name" value="SSF48592"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52029">
        <property type="entry name" value="SSF52029"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54849">
        <property type="entry name" value="SSF54849"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02348">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00296">
        <property type="entry name" value="CHAPERONINS_CPN60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 6" id="KW-0143">Chaperone</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="30"/>
            <end position="33"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="51"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="87"/>
            <end position="91"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="415"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="478"/>
            <end position="480"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="494"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC92318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="548" mass="57723" checksum="C75DB16A9EC20D08" modified="2018-07-18" version="1">MAAKEVIFGDAARAKMVEGVNILANAVKVTLGPKGRNVILERSFGAPTITKDGVSVAKEIELKDKLMNMGAQMVKEVASRTSDNAGDGTTTATVLTQAIVREGMKYVAAGMNPMDLKRGIDKAVAATVEELKRIAKPCTTTKEIAQVGSISANSDTSIGDRIAEAMDKVGKEGVITVEDGKSLNDELDIVEGMQFDRGYLSPYFINTPEKQVAILENPFVLLYDKKISNIRDLLPTLEQVAKAGRPLLIVAEDIDGEALATLVVNNIRGILKTCAVKAPGFGDRRKAMLEDIAVLTGGQVIAEEVGLTLEKVTLADLGQAKRIEVSKENTIVIDGAGQTLAIEARVKQIRVQIEEATSDYDREKLQERVAKLAGGVAVIKVGAATEVEMKEKKARVEDALHATRAAVEEGIVPGGGVALLRARAAINVKGDNPDQEAGIKIVLRAMEEPLRMIVQNAGEEASVVVAAVLAGKGNFGYNAANGTYGDMVEMGVLDPAKVTRSALQNAASIASLMLTTDCMIAEIADDKAAGGMGGMGGMGGMGGMDGMM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GX83</accession>
    <name>A0A2S9GX83_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Prephenate dehydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2988</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92329">
        <property type="protein sequence ID" value="PRC92329"/>
        <property type="gene ID" value="S2091_2988"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="200" mass="22380" checksum="0D4E74A0F14F6598" modified="2018-07-18" version="1">MIMFYKSIAKASDYSGNLDAYNVIATLGPTGTSSENTALFFGTKMRSKPKIKLFDTYEDAEHFIFSSQHSLMLVANAYKRINEFYISDRTNPLLSFFFNTPPYGIATKTGVDLTELNRERILHIASHHAPKHLIAKLLPNHQFNVLDAASTSLAAKMVAKGEVDACLTTKIACEKEGLVLQSHEVDIQMLWTAFTKKVQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GX85</accession>
    <name>A0A2S9GX85_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2935</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92276">
        <property type="protein sequence ID" value="PRC92276"/>
        <property type="gene ID" value="S2091_2935"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="131" mass="14916" checksum="CD9F495AEB44B2D7" modified="2018-07-18" version="1">MLESITISISIQRNWKDLYEAIWRPEDFPKWASGLTKSPLIKEGASWKAEGPEGPITVRFTDHNEFGVMDHYVDLGNGTEIYVPLRVIPNSDGADVLLTLFRQAGMSNSKFKEDVDWVKRDFLTLKALVMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXB7</accession>
    <name>A0A2S9GXB7_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 6 8">Proline iminopeptidase</fullName>
            <shortName evidence="6">PIP</shortName>
            <ecNumber evidence="4 6 8">3.4.11.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Prolyl aminopeptidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">S2091_3024</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 6 8">
            <text>Release of N-terminal proline from a peptide.</text>
            <dbReference type="EC" id="3.4.11.5"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 6 8">Belongs to the peptidase S33 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.5" evidence="4 6 8"/>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92365">
        <property type="protein sequence ID" value="PRC92365"/>
        <property type="gene ID" value="S2091_3024"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002410">
        <property type="entry name" value="Peptidase_S33"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005944">
        <property type="entry name" value="Pro_iminopeptidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43722">
        <property type="entry name" value="PTHR43722"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006431">
        <property type="entry name" value="Pept_S33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00793">
        <property type="entry name" value="PROAMNOPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01249">
        <property type="entry name" value="pro_imino_pep_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8 10" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 8" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="9">
        <location>
            <begin position="40"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="7">
        <location>
            <position position="114"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="268"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="7">
        <location>
            <position position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00021843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR006431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR006431-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003421"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC92365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="321" mass="35661" checksum="3C0B8FACE0EF41AD" modified="2018-07-18" version="1">MPEIISPLFPEIQPYRSGHLSVDGGHSLYWEECGNPNGQPVLFLHGGPGAGLSPSHRQFFDPAYYRIVLFDQRGAGKSTPLGEYRHNTTPLLIQDIEAIRTMLKIDQWLVFGGSWGSTLALAYGEAHPSACLGFVLRGIFLCTQVEVEWFINGMKNFFPEVYAEFAAAIPSDERHDLLDAYAKRLFSDDPALYLPAARSWSRYEGSCLFLEPQASAVEAFEKEEVSLGLGRLEAHYMVYGGFMEEDQLIKNIDKISHLPAVIVQGRYDVICPPTSAFRLHAAWPESVLKVIPTAGHAALEPGTAAALVAATEQFKLQRRFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXG5</accession>
    <name>A0A2S9GXG5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Serine/threonine protein phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3015</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92356">
        <property type="protein sequence ID" value="PRC92356"/>
        <property type="gene ID" value="S2091_3015"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016539">
        <property type="term" value="P:intein-mediated protein splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006470">
        <property type="term" value="P:protein dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00143">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006141">
        <property type="entry name" value="Intein_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015655">
        <property type="entry name" value="PP2C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832">
        <property type="entry name" value="PTHR13832"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00331">
        <property type="entry name" value="PP2C_SIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="SSF81606"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50817">
        <property type="entry name" value="INTEIN_N_TER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="1">
        <location>
            <begin position="2"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="315" mass="35077" checksum="293959EB78941333" modified="2018-07-18" version="1">MRFSVYQESHIGGRKVNQDRMGYCFTRDSLLLLLADGMGGHIMGEMAATIAMQTIGNLFQQQAKPCIGRPERFLEESFLAAHKEIHRFKIINNLPDTPRTTIVACLIQHDTAFWAHCGDSRLYWMRNGQLLLRTRDHSRLETLIAQGAIDASQRDTHPDRNKLFNCLGAPNLPIVEMSRRVNLQAGDVMLLCSDGLWSVLPEHVLLQHLRERTIVRAVPELLNKALSIAGKSSDNVTALAMMWEGGDDNPSTVTTHTLPIGAVTTTIHSTILDDERSGIQEGGEEIDGFDEADIEKAIEEIRKAIQKSSKVGLKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXH8</accession>
    <name>A0A2S9GXH8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glycosyl transferase family 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_2800</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92425">
        <property type="protein sequence ID" value="PRC92425"/>
        <property type="gene ID" value="S2091_2800"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="275"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_trans_2-like" evidence="3">
        <location>
            <begin position="49"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC92425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="386" mass="42954" checksum="D862AD72B286F5B6" modified="2018-07-18" version="1">MGVEFWLSLTVFLITVAISLEIVIGVRKIKQLEDTAPVSAPAGDAPKVSIIVSALNEAETIEPALLSLLAIDYPNLEIIAINDRSTDATPEILDRIAKTHPGLRVLHLSTLPPGWLGKNHALYQGAQLASGSYLLFTDADVIFEPSSISRAVNYCELFQVDHLAILFKVIAKTQLLRMLLVLFQIGVLARYKPWKVATSTKHFLGIGGFNMVRKSAYEESGGHAALALQVLDDLMLGKLIKAKGYCQHVLSTSKLITVEWYQNTPGMVKGLQKNIFCAFAYQISQLIGMTLFILVLRFWPLVGLFVTDGVTRMLNAASVLASCALCVDIIRRNEWEYRCLLFAPIAMSVELLMWWRSCLLTLLRGGIDWRGTHYPLRDLRQAQLKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXJ1</accession>
    <name>A0A2S9GXJ1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Aerobic-type carbon monoxide dehydrogenase middle subunit CoxM/CutM-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2820</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92445">
        <property type="protein sequence ID" value="PRC92445"/>
        <property type="gene ID" value="S2091_2820"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005107">
        <property type="entry name" value="CO_DH_flav_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036683">
        <property type="entry name" value="CO_DH_flav_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016167">
        <property type="entry name" value="FAD-bd_PCMH_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002346">
        <property type="entry name" value="Mopterin_DH_FAD-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03450">
        <property type="entry name" value="CO_deh_flav_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00941">
        <property type="entry name" value="FAD_binding_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01092">
        <property type="entry name" value="CO_deh_flav_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55447">
        <property type="entry name" value="SSF55447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="SSF56176"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0274">FAD</keyword>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="331" mass="35573" checksum="485B14B3BA2562CB" modified="2018-07-18" version="1">MNPFQYSRAQSIDQAIQSIRAADGGNARFIAGGTNLLDLMKMNVEQPGQLIDINYLPLSELHIDNTMLSIGALARMSDVAANTEVARRFPVIAQSLLASASPQLRNMASIGGNMMQRTRCSYFRDTACACNKREPGSGCAALGGDNRRHAILGISPHCIATHPSDLAVALMALSARIKLHGPNSDRTVPIDDFFLVPGSTPNLEHNIQIDELIVAIEVPASPLATRSFYLKVRERASFEFALTSAAVALDIRNGVIAESRIVLGGIATKPWRARDAEVYLAGKPVQESHFVAAAHIALAQAQPGKDNKFKVKLAQRTVVRALTTLAAGEIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXJ5</accession>
    <name>A0A2S9GXJ5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2805</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92430">
        <property type="protein sequence ID" value="PRC92430"/>
        <property type="gene ID" value="S2091_2805"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025361">
        <property type="entry name" value="DUF4265"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14085">
        <property type="entry name" value="DUF4265"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="94"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="127"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="328" mass="36067" checksum="A2FEB7572E3BA61D" modified="2018-07-18" version="1">MAQSSASKLVIISIISYIISLVTPAFSYHLGQNPYAQYCQGFYPLLIGWFPLLFELISIPQGKGTFDGLGCFAWLSNPLIFIAWIGISQKAKTISIFTAVTAIILSLTFLSINQLPTGEPGQNWSNITVNIGFFLWLISMVLAVLSANCLEISNKKSMSVSTRNEPGKTISTETRNGLIKIRVNLPNRATIGAESFWAKNLGNGNYQIKNIPFCAFGLNFDDIVRAEISPVSEIPVIKNLVEAKGHQTLRVTFLGIGTKEERLEVIKSVQTEYITYEGNDSDLYALDVAPGGDYGTLFSDLKALELKIILVVETCESRIEGSFDDSLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXP7</accession>
    <name>A0A2S9GXP7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">5'-nucleotidase/2'3'-cyclic phosphodiesterase and related esterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_2869</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the 5'-nucleotidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92494">
        <property type="protein sequence ID" value="PRC92494"/>
        <property type="gene ID" value="S2091_2869"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0110165">
        <property type="term" value="C:cellular anatomical entity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009166">
        <property type="term" value="P:nucleotide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.780.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008334">
        <property type="entry name" value="5'-Nucleotdase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036907">
        <property type="entry name" value="5'-Nucleotdase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006146">
        <property type="entry name" value="5'-Nucleotdase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006179">
        <property type="entry name" value="5_nucleotidase/apyrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11575">
        <property type="entry name" value="PTHR11575"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02872">
        <property type="entry name" value="5_nucleotid_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01607">
        <property type="entry name" value="APYRASEFAMLY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55816">
        <property type="entry name" value="SSF55816"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00786">
        <property type="entry name" value="5_NUCLEOTIDASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="5_nucleotid_C" evidence="3">
        <location>
            <begin position="335"/>
            <end position="522"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006654"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU362119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC92494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="623" mass="66861" checksum="5CAD32F90E29E64A" modified="2018-07-18" version="1">MRTASLIRAARSEFSNSMLFDNGDAIQGTPLADYQAIANPIKCDQTLAVYKVMNATKYDAAGIGNHEFNFGLPYLAQVTGSKFNVDGLPAVADQQQCAGPNFPQILANVVSNRDQQPLFKPYVILDKVVSATDPNGKTVSATIKVGVIGFTPPTITSWDSRWLNGKVSTVGIKETAEKYIPEMRAKGADIVVAISHGGLDNSPYTPSMEDGNYYLSQVAGIDAMLIGHVHQIFPNASSTVPQFQLPGVDKVAGLVNGVPTVMANYWGKHLGVIQLALTYNGTHWVVDKTKTVVQTRGTTTLDANKAATTVAADPTIAPIIEAEHQATIAYMKTPVGRTDFEMSSFFADLGDPTAIQIVNQAQTEYVSNVVKTNFPQLANLPVLSVSAPFKSGRGGAHDYTDVPAGNLVLSNTADLYYFANTITAVKISGADLHAWLEKSAYRFNQINPTLTTDQALINPNSYGYNFDTFTSKDISYEIDVTQPLGARIKNLTYLGAAVADSQQFIVATNNYRASGGGNFPGLDGSKTIYSSEDANRAVLAAYVKAQKSNLSLSSNGSDRSWHFTKVATLGNVTYTAPQGKLALASSVGMRNLSVLSSDPLTGLTIYKVDLNMVDLTRVSLTKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXU3</accession>
    <name>A0A2S9GXU3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2903</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92528">
        <property type="protein sequence ID" value="PRC92528"/>
        <property type="gene ID" value="S2091_2903"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="107" mass="11924" checksum="51D3F362AF67DF9C" modified="2018-07-18" version="1">MLASLELLEEIQLRSGLQVRVFRSSDLGECDPGTEAKSCPKSQLYIVRSVVTEGPANNTLWTSARFTQWKLAGRLSEEAVNLQNKQEEYFGAVSFELSACRAPENVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXW2</accession>
    <name>A0A2S9GXW2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2603</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92548">
        <property type="protein sequence ID" value="PRC92548"/>
        <property type="gene ID" value="S2091_2603"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="62"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="100"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="131"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="168" mass="18222" checksum="7955CC187A81CC88" modified="2018-07-18" version="1">MSQLLQMIPTWVFFLFFTLLYLGYAQSKTREVSMARLTILPFAMVILSLYSVWTAFGSSLAFGAWIIGAGAALAVNSKLQHGRGVTRHTISGHVVVPGSWLPLGLMMSIFVTKFIVAFMIASHAMLANTPAFPVIASFCFGVFSGTFFARSLYIGHAARSQTGTLIAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYA0</accession>
    <name>A0A2S9GYA0_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Type II secretion system core protein G</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">S2091_2757</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the GSP G family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92702">
        <property type="protein sequence ID" value="PRC92702"/>
        <property type="gene ID" value="S2091_2757"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015627">
        <property type="term" value="C:type II protein secretion system complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015628">
        <property type="term" value="P:protein secretion by the type II secretion system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000983">
        <property type="entry name" value="Bac_GSPG_pilin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013545">
        <property type="entry name" value="T2SS_protein-GspG_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010054">
        <property type="entry name" value="Type2_sec_GspG"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08334">
        <property type="entry name" value="T2SSG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00813">
        <property type="entry name" value="BCTERIALGSPG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01710">
        <property type="entry name" value="typeII_sec_gspG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="15"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="domain" description="T2SSG" evidence="11">
        <location>
            <begin position="39"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004377"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF08334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PRC92702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="144" mass="15748" checksum="43C12EFF9BBC35B0" modified="2018-07-18" version="1">MYKYKIPTTPPKNTGFTLLELLVVIVIIGLLAAYVGPKYFAQLGKSEVTIAKSQIEAFDKAVDTFRLDVGRFPTAEEGLSALNIKPADAEKWNGPYLKKDIPLDPWGHPYIYKVPGTKGDFEIISYGKDGQPGGVGDDADISNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYB7</accession>
    <name>A0A2S9GYB7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2753</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92698">
        <property type="protein sequence ID" value="PRC92698"/>
        <property type="gene ID" value="S2091_2753"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="25"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="183" mass="20755" checksum="F6286A5F3574DA22" modified="2018-07-18" version="1">MTINRIDFAPPTFARTLYRTQIRTWFFICIGLALCASAIVIGLQQQHNIDANKKTLQLLTPQLNARNNPKTVRKKSTITETQANAVNTAIAQLNLPWRDVLDAMESATPTTIALLSLEPDARRNAVKGIAEAKDSDDMVRYIELLKKEDFFSDIFITMHEINQLDPNKPVRFQFEAHWQNAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYI6</accession>
    <name>A0A2S9GYI6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Polysaccharide deacetylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_2498</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92768">
        <property type="protein sequence ID" value="PRC92768"/>
        <property type="gene ID" value="S2091_2498"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029030">
        <property type="entry name" value="Caspase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002509">
        <property type="entry name" value="NODB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01522">
        <property type="entry name" value="Polysacc_deac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52129">
        <property type="entry name" value="SSF52129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="SSF88713"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51677">
        <property type="entry name" value="NODB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="15"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="domain" description="NodB homology" evidence="3">
        <location>
            <begin position="264"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="796"/>
            <end position="829"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="830"/>
            <end position="863"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="864"/>
            <end position="897"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC92768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="910" mass="100394" checksum="248BD5048078D919" modified="2018-07-18" version="1">MNFICFSYIGLKVNYIKIIAIALISILIAVGGTLFYRSKSSNNAIIPMNSSANDAALENKFKEILSNYRKIIVLVADEDKLSKPELDASIRIGQEVFHENQEKIAEVERTLDSFVTSTQTTRFETTNRLLDYVESDNTLFDADRLAFKDVLASLQTSVTKDTSLTAIKMHKRISEDLEALNEIEHNYEKEMGQIFSHFEQRGIVLKREKWDTYVAHLKQLYSREKILKDYGTVLPAAIKTEPVVGVPENSKPEGEIFGNKLPPKTIVLTFDDGPHKQYTEEIAAILKQYDAPAVFFNVGQNLGSVDANGTAKLSPAAKISQKLRDSGYVIGNHSFTHAQLSKLSGDNLHAEIFNTDALLKAMDANRSTLFRFPYGAHNQEGLQALEKAHLKSVMWNIDSLDWADPVPSSIADRVLRTVEKEGRGIILFHDIHDRAVKALPIVLDRLVAEGYQFAGWDGNAFTVAKSDKAPQEKVSVSSGYSNSWAIVIGINDYAKWPKLQYAVQDSQGVRQILIEKLGFPSDHVFSLQNGEATRNGILAMFHDRLANSSVQKDDRIFVFFAGHGATRKLSSGRDLGYIVPVDSDPNEFAADAIPMTEIQNISESLNSKHVFFVMDACYSGLGLTRGGGSSNYLRDNAKRIGRQMLTAGGTDQMVADGGPNGHSVFTWTLLQGLSGKADLNGDGIITATELAAYVAPAVSAVSQQTPAFGSLPGSEGGDFVFELPAETEYINTATTQLSSDAIALNSKLDSTRSEPVIDEKSIKTKSNPVIKVKDLQGTVQTIVTPTAVPVSARQMAQHANDRGLQLYKEKQYAEAESQFTEALKLRPDFALAANNLGFVYYKQEKYVEAARWFENTIKIDPSRAIAYLNFGDAQFHGGDKDKARKGYQTFLELSPNSPSAGYAKQQLEKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYJ9</accession>
    <name>A0A2S9GYJ9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Helix-turn-helix domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2466</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92736">
        <property type="protein sequence ID" value="PRC92736"/>
        <property type="gene ID" value="S2091_2466"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="267" mass="29761" checksum="F4CE53B8FB12F179" modified="2018-07-18" version="1">MNKALLSMILVLRLNHAAKFVLLALAMLADEAGKNIWISIDKLSFFVSMHRRTVVRTLRVLEQSLILQTVKNEHGGAPGASCHRQIDIARIEEILCKQRLAECENGGGIDFSVMKEIALCTGGALPSKVVVVDFKDTTTTLNSEAPAQDLSTYDWPESLRPDDRAAILDIFNASSQETKANQYILDELRAAMAHREIRLKVAWVKGVLLRGIERTDTGRAYEKARLHRKVVGPVSSKADLVPKTSLEKQVIHERIKKLKEAFKNGPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYL4</accession>
    <name>A0A2S9GYL4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">4Fe-4S single cluster domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_2520</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92790">
        <property type="protein sequence ID" value="PRC92790"/>
        <property type="gene ID" value="S2091_2520"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC92790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="393" mass="44479" checksum="68795DB48FD1D1D4" modified="2018-07-18" version="1">MNAQIESHQQRKLAIAERLPVLLAGAPDLAQRFKAVREFSSQIRASEYHLTNACNIRCKGCWFFEFGHDKTSTEAKDLADWEQFTIDQSYQGINCALLIGGEPTLFADRIGAFAETMQYVSISTNGLKPFPNRDPFRNVTVFISLFGGGPLDDQLRAIKPSGTAFTGLFETTLKNYHNDPRATFVFAATEDGIEYIEPTVKRIRDNGNVVTFNFYSKYNTGHPLRMKNERRLLEEMQRVRNEYPETVLNHPSHIEAIVTGKTWCGTFGHDVCPSISQDHPGNAARQANGNPTLPLFNAYKADLKTLEICCTSGRCSDCRDSQAVYSWLMVSLSKSLDSIETLTTWVEVAESYWRQFIWSPYHHSAKNKPDQRELNLAGIHIERNSRPLSHFPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYL9</accession>
    <name>A0A2S9GYL9_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cytochrome bo(3) ubiquinol oxidase subunit 4</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Cytochrome o ubiquinol oxidase subunit 4</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Oxidase bo(3) subunit 4</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">Ubiquinol oxidase polypeptide IV</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Ubiquinol oxidase subunit 4</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">S2091_2486</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Heterooctamer of two A chains, two B chains, two C chains and two D chains.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome c oxidase bacterial subunit 4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92756">
        <property type="protein sequence ID" value="PRC92756"/>
        <property type="gene ID" value="S2091_2486"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009486">
        <property type="term" value="F:cytochrome bo3 ubiquinol oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015990">
        <property type="term" value="P:electron transport coupled proton transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005171">
        <property type="entry name" value="Cyt_c_oxidase_su4_prok"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014210">
        <property type="entry name" value="Cyt_o_ubiqinol_oxidase_su4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03626">
        <property type="entry name" value="COX4_pro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02847">
        <property type="entry name" value="CyoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 15" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="28"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="59"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="89"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00025694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00030071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00030211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00031887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00032185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="PRC92756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="163" mass="17772" checksum="C2DEAE5ADD2C20F3" modified="2018-07-18" version="1">MSAHSHDQHHQHHDSHELHADHGSLKSYATGFILAVILTAIPFWLVMGNVFEKSSTTGFVILGFAAVQIVVHMIYFLHMNTKSEGGWSMLALIFTGILVIIMMSGSLWVMYHLNHNMMPGMMTETRTETVPESIAKPAGLPITLPTALPTAAPTPAEPASTAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYU4</accession>
    <name>A0A2S9GYU4_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ribosome-binding factor A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">rbfA</name>
        <name evidence="4" type="ORF">S2091_2295</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RbfA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92878">
        <property type="protein sequence ID" value="PRC92878"/>
        <property type="gene ID" value="S2091_2295"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030490">
        <property type="term" value="P:maturation of SSU-rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00003">
        <property type="entry name" value="RbfA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000238">
        <property type="entry name" value="RbfA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023799">
        <property type="entry name" value="RbfA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33515">
        <property type="entry name" value="PTHR33515"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02033">
        <property type="entry name" value="RBFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89919">
        <property type="entry name" value="SSF89919"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00082">
        <property type="entry name" value="rbfA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="123"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC92878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="142" mass="15704" checksum="D3110A07412C3C6F" modified="2018-07-18" version="1">MAKNSKSIPGRGLRVADQIQRDLSVIISAELKDPRVGMITLTEVQVTPDYAHAKVYFTSLRDTPEQIKVTLTCLNNAAGFLRMHLGKCLHIHTLPQLHFVHDTSTMYGMAMSKLIDEAMATSAPLVEPESDQDENPESGIKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYY4</accession>
    <name>A0A2S9GYY4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acyl-CoA-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2362</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92945">
        <property type="protein sequence ID" value="PRC92945"/>
        <property type="gene ID" value="S2091_2362"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000062">
        <property type="term" value="F:fatty-acyl-CoA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.80.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000582">
        <property type="entry name" value="Acyl-CoA-binding_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035984">
        <property type="entry name" value="Acyl-CoA-binding_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014352">
        <property type="entry name" value="FERM/acyl-CoA-bd_prot_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00887">
        <property type="entry name" value="ACBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00689">
        <property type="entry name" value="ACOABINDINGP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47027">
        <property type="entry name" value="SSF47027"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51228">
        <property type="entry name" value="ACB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ACB" evidence="1">
        <location>
            <begin position="3"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="83" mass="9322" checksum="BAD5967635BA77E0" modified="2018-07-18" version="1">MSLSEQFAQAQLDSKNLPERPDNMTLLKIYALFKQTSNGDASGERPGFTDMIGRAKWDAWNSLAGTAQEEAQQQYIDLINDLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYZ3</accession>
    <name>A0A2S9GYZ3_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Ferredoxin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_2358</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>[3Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:21137"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 7">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92941">
        <property type="protein sequence ID" value="PRC92941"/>
        <property type="gene ID" value="S2091_2358"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051538">
        <property type="term" value="F:3 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000813">
        <property type="entry name" value="7Fe_ferredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022569">
        <property type="entry name" value="Fd_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11953">
        <property type="entry name" value="DUF3470"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00037">
        <property type="entry name" value="Fer4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12800">
        <property type="entry name" value="Fer4_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00354">
        <property type="entry name" value="7FE8SFRDOXIN"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 7" id="KW-0003">3Fe-4S</keyword>
    <keyword evidence="7" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="7" id="KW-0249">Electron transport</keyword>
    <keyword evidence="4 7" id="KW-0408">Iron</keyword>
    <keyword evidence="5 7" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="8">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="8">
        <location>
            <begin position="31"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU364098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC92941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="108" mass="12199" checksum="9F8ACABFB6CA7304" modified="2018-07-18" version="1">MTHVVTESCIRCRYTDCVDVCPVDCFRVGPNFLAIDPDECIDCAVCVAECPVNAIYAEEDVPADQQDYLKLNADLSRTWPSITKTIAPLPDADDWKDVKDKIQYLKRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYZ7</accession>
    <name>A0A2S9GYZ7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2350</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92933">
        <property type="protein sequence ID" value="PRC92933"/>
        <property type="gene ID" value="S2091_2350"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="72"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="145" mass="13901" checksum="D781966E25BD425D" modified="2018-07-18" version="1">MSTITSSAPASPFTPPAYVNPVASSSTYAGLSTTATKLGLESSIVANLGSSSSGTPLYNAVGLLNSIITAGQPAAPSSATSTGSAGATPPASTSGIYTASGTVQGTSTNLNANWATILKSEPATAGTVAADSTIQGILSSISTTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZ54</accession>
    <name>A0A2S9GZ54_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="11">LolCE: lipoprotein releasing system, transmembrane protein, LolC/E family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">S2091_2105</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93019">
        <property type="protein sequence ID" value="PRC93019"/>
        <property type="gene ID" value="S2091_2105"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042953">
        <property type="term" value="P:lipoprotein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011925">
        <property type="entry name" value="LolCE_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025857">
        <property type="entry name" value="MacB_PCD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12704">
        <property type="entry name" value="MacB_PCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02212">
        <property type="entry name" value="lolCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="11" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="29"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="279"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="338"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="386"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="domain" description="MacB_PCD" evidence="10">
        <location>
            <begin position="34"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="9">
        <location>
            <begin position="307"/>
            <end position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF12704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC93019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="420" mass="45716" checksum="2070FE0AF9644D73" modified="2018-07-18" version="1">MNFLKKLPYEWQIGLRYTRAGRRSGRNSFISFISLISMAGIGLGVAALIIVLSVMNGFQKEVRDRMLSVVSHIEVSGAGGVLPDWQETARETLLNKHVKAAAPYVEGQALIISDSMRGVIVRGILPEQEPTVSEVISKIKQGSFTSLQSGEFNIVIGKDLALALDAHLGDKITLAVPQGQVTPAGVTPRLKSFTVTGIFEAGTYEYDSALVFVQMTDAEKLFRLSAPTGVRLRVDDLLQAPAIALELSTSLSGDLLLRDWSQQNRNYFAAVKVEKRMMFIILTLIIAVAAFNLVSTLVMTVRDKQADIAILRTLGASPASIMKIFMVQGSMVGTLGTLLGVGLGVIVALNIPAMVGFFEHLFGVQFLDKAIYFITSVPSDLHWDDVSYIGGMALVFALLSTIYPSWRASNVKPAEALRYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZ74</accession>
    <name>A0A2S9GZ74_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Bifunctional chorismate mutase/prephenate dehydratase</fullName>
            <ecNumber evidence="8">4.2.1.51</ecNumber>
            <ecNumber evidence="7">5.4.99.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="18">Chorismate mutase-prephenate dehydratase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="17">p-protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="23" type="ORF">S2091_2420</name>
    </gene>
    <organism evidence="23 24">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="23 24" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="23 24">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>H(+) + prephenate = 3-phenylpyruvate + CO2 + H2O</text>
            <dbReference type="Rhea" id="RHEA:21648"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:18005"/>
            <dbReference type="ChEBI" id="CHEBI:29934"/>
            <dbReference type="EC" id="4.2.1.51"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>chorismate = prephenate</text>
            <dbReference type="Rhea" id="RHEA:13897"/>
            <dbReference type="ChEBI" id="CHEBI:29748"/>
            <dbReference type="ChEBI" id="CHEBI:29934"/>
            <dbReference type="EC" id="5.4.99.5"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5">Amino-acid biosynthesis; L-phenylalanine biosynthesis; phenylpyruvate from prephenate: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="6">Metabolic intermediate biosynthesis; prephenate biosynthesis; prephenate from chorismate: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="23">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.51" evidence="8"/>
    <dbReference type="EC" id="5.4.99.5" evidence="7"/>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC93003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93003">
        <property type="protein sequence ID" value="PRC93003"/>
        <property type="gene ID" value="S2091_2420"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00120">
        <property type="reaction ID" value="UER00203"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00121">
        <property type="reaction ID" value="UER00345"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004106">
        <property type="term" value="F:chorismate mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004664">
        <property type="term" value="F:prephenate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046417">
        <property type="term" value="P:chorismate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009094">
        <property type="term" value="P:L-phenylalanine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.59.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008242">
        <property type="entry name" value="Chor_mutase/pphenate_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036263">
        <property type="entry name" value="Chorismate_II_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036979">
        <property type="entry name" value="CM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002701">
        <property type="entry name" value="CM_II_prokaryot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010957">
        <property type="entry name" value="G/b/e-P-prot_chorismate_mutase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001086">
        <property type="entry name" value="Preph_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018528">
        <property type="entry name" value="Preph_deHydtase_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01817">
        <property type="entry name" value="CM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00800">
        <property type="entry name" value="PDT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001500">
        <property type="entry name" value="Chor_mut_pdt_Ppr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00830">
        <property type="entry name" value="CM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48600">
        <property type="entry name" value="SSF48600"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01807">
        <property type="entry name" value="CM_P2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51168">
        <property type="entry name" value="CHORISMATE_MUT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00857">
        <property type="entry name" value="PREPHENATE_DEHYDR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00858">
        <property type="entry name" value="PREPHENATE_DEHYDR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51171">
        <property type="entry name" value="PREPHENATE_DEHYDR_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="11" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="12" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="14" id="KW-0413">Isomerase</keyword>
    <keyword evidence="15" id="KW-0456">Lyase</keyword>
    <keyword evidence="16" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="13" id="KW-0584">Phenylalanine biosynthesis</keyword>
    <keyword evidence="24" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chorismate mutase" evidence="20">
        <location>
            <begin position="1"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="domain" description="Prephenate dehydratase" evidence="21">
        <location>
            <begin position="91"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="domain" description="ACT" evidence="22">
        <location>
            <begin position="278"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="site" description="Essential for prephenate dehydratase activity" evidence="19">
        <location>
            <position position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00002364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00004817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00012404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00013147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00014401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00031175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00031520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="PIRSR" id="PIRSR001500-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS51168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS51171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="EMBL" id="PRC93003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="358" mass="38884" checksum="DE48A2CE5E0CAF44" modified="2018-07-18" version="1">MSIDKQLQPLREKIDAVDAQILSLLNSRAELAQQVGHLKANTNAPVFRPEREAQVLRGVAERNVGPLPSLDIQLIFREIMSACRALERRVTVAYLGPAGTFSEQAVFQQFGHAIVLLPCVSIDEVFRTTEAGTADFGVVPVENSSEGAVNRTLDLLLQTSLSISGELSIPVQHSLMTASGDLAGITKICAHSQALAQCQTWLNQHYPNVERVAVASNGEAARMASLDSSVAAIAGETAGAQYELQAVHAHIQDDPHNRTRFVVIGNSHCQPSGKDQTSLVLAVPNKAGAVYSLLAPFMQFGVSMTRFESRPARTGTWEYYFYVDVEGHQHDESVARSLSELRNSAAFFKILGSYPLSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZ76</accession>
    <name>A0A2S9GZ76_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">C4-dicarboxylate transport protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">dctA</name>
        <name evidence="10" type="ORF">S2091_2117</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate across the membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93031">
        <property type="protein sequence ID" value="PRC93031"/>
        <property type="gene ID" value="S2091_2117"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015293">
        <property type="term" value="F:symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006835">
        <property type="term" value="P:dicarboxylic acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3860.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01300">
        <property type="entry name" value="C4_dicarb_transport"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023954">
        <property type="entry name" value="C4_dicarb_transport"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001991">
        <property type="entry name" value="Na-dicarboxylate_symporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018107">
        <property type="entry name" value="Na-dicarboxylate_symporter_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036458">
        <property type="entry name" value="Na:dicarbo_symporter_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42865">
        <property type="entry name" value="PTHR42865"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00375">
        <property type="entry name" value="SDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118215">
        <property type="entry name" value="SSF118215"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00713">
        <property type="entry name" value="NA_DICARBOXYL_SYMP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00714">
        <property type="entry name" value="NA_DICARBOXYL_SYMP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0769">Symport</keyword>
    <keyword evidence="5 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="47"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="77"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="143"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="183"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="225"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="350"/>
            <end position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC93031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="414" mass="43987" checksum="FF062E3288BAD1C7" modified="2018-07-18" version="1">MKKPFYKILYVQVLFAICCGILIGVFQPHFGVELKPLGDGFIKLIKMIIAPVIFCTVVSGIAGMQDIKKVGRVGGKALIYFEVLSSIALLIGLIVANVIRPGDGFNANLASLDTSGIAQFTTKAMPTTVEFIMNIIPETLVGAFAHGDILPVLLIAILFGFALSTLGEKGKPILHLVDDLSKVIFAVVGILMKAAPIGAFGAMAFTISKYGIASLLPLAKLMGSFYLTCGLFIFVVLGIVAKLTGFSIWRFLVYIKEELLIVLGTSSSESGLPLLMEKLQRLGCAKSVVGLVVPTGYSFNLDGTNIYMTMAALFIAQATNTDLTLTQQLTILGVAMLTSKGASGITGAGFITLAATLAVVPTIPITGMALILGIDRFMSECRALTNFIGNGVATIVVSKWENELDMSILKQELS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZ90</accession>
    <name>A0A2S9GZ90_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">LysR substrate binding domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2363</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92946">
        <property type="protein sequence ID" value="PRC92946"/>
        <property type="gene ID" value="S2091_2363"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="294" mass="32676" checksum="B619142526EBFFE3" modified="2018-07-18" version="1">MKWDDIKLFLAVVEQGSLSAAARELKLGQPTLSRRIGELESLIGEALFIRQTQGVTLTSAGEKLLPAAQRMAEWANEATQSLSKQKQQLSGKIKIAAPPGVALDFVVPLAQTLQQHHPQLRIEVLAGIETLNLSRGEADISLRTRAPTDDDLICLDQIKAPMRILASSAYIKQLPDSYTLDDLDWICWSDSHQELQMVQELKKQVKQFNPVFTSNDFNIQMAACRAGLGVMLLAKVPPIFPHLNQLHELNIAHGFSSEAELFVVCHKRHRHLPKVAIVLEAISAQFALARRQMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZ98</accession>
    <name>A0A2S9GZ98_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 13">Chaperone protein ClpB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">clpB</name>
        <name evidence="15" type="ORF">S2091_2140</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Homohexamer. The oligomerization is ATP-dependent.</text>
    </comment>
    <comment type="subunit">
        <text evidence="13">Homohexamer; The oligomerization is ATP-dependent.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 13">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the ClpA/ClpB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93054">
        <property type="protein sequence ID" value="PRC93054"/>
        <property type="gene ID" value="S2091_2140"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042026">
        <property type="term" value="P:protein refolding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009408">
        <property type="term" value="P:response to heat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1780.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017730">
        <property type="entry name" value="Chaperonin_ClpB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019489">
        <property type="entry name" value="Clp_ATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036628">
        <property type="entry name" value="Clp_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004176">
        <property type="entry name" value="Clp_R_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001270">
        <property type="entry name" value="ClpA/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018368">
        <property type="entry name" value="ClpA/B_CS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028299">
        <property type="entry name" value="ClpA/B_CS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041546">
        <property type="entry name" value="ClpA/ClpB_AAA_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07724">
        <property type="entry name" value="AAA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17871">
        <property type="entry name" value="AAA_lid_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02861">
        <property type="entry name" value="Clp_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10431">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00300">
        <property type="entry name" value="CLPPROTEASEA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01086">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81923">
        <property type="entry name" value="SSF81923"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03346">
        <property type="entry name" value="chaperone_ClpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51903">
        <property type="entry name" value="CLP_R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00870">
        <property type="entry name" value="CLPAB_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00871">
        <property type="entry name" value="CLPAB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 12" id="KW-0143">Chaperone</keyword>
    <keyword evidence="7 13" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="13" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0677">Repeat</keyword>
    <keyword evidence="13" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="Clp R" evidence="14">
        <location>
            <begin position="3"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="13">
        <location>
            <begin position="412"/>
            <end position="492"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00026057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU004432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU362034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="PRC93054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="861" mass="95376" checksum="1D0C69F09486A379" modified="2018-07-18" version="1">MRFDKLTTKLQAALANAQSLAVRHDNAYIEPVHILLALLDDDDMSASSILQRAGVNVAALTTSLNAALGRFAKISGHGGEVQLSRESSALFNLAEKESQQRGDQFLASEIVLLTFCDDKSEAGQLARQHGLNKTAMKAAIEAVRGGAAVDAPEAEGQREALKKYTVDLTALARKGKLDPVIGRDDEIRRTIQILQRRSKNNPVLIGEPGVGKTAIVEGLAQRIVNGEVPDSLKSKRVLSLDMASLLAGAKYRGEFEERLKSVLKEIALDEGQTIVFIDELHTMVGAGKAEGAIDAGNMLKPALARGELHCVGATTLDEYRKYVEKDAALERRFQKVLVDEPSVEATIAILRGLQEKYEVHHGVDITDPAIIAAAELSHRYITDRFLPDKAIDLIDEAAAKIKIEIDSRPEVMDKLDRRTIQLKIEREAIKKEKDDGSKKRLLLLDEEIVKLEREYADLEEIWKAEKASVQGSTLIKEEIEKARLQMEEARRKGDWQAMSELQYGRLPELEAQQKQIDKGEAKADGKTPKLRLLRTQVGAEEIAEVVSRATGIPVSRMMTGEREKLLQMEQRLHQRLVGQDEAVVAVSDAIRRSRAGLSDTTRPYGSFLFLGPTGVGKTELCKALAGFLFDSEDALIRIDMSEFMEKHSVARLIGAPPGYVGYEEGGYLTEAVRRKPYSVILLDEVEKAHHDVFNVLLQVLDDGRMTDGQGRTVDFKNTVIVMTSNLGSHRIQAMEESEPSLVKMAVMAEVREHFRPEFINRIDEIVVFHALDAKNIGSIAKIQLGILQGRLAKLEIGFEINNEALLKIAEAGFDPVYGARPLKRAIQQMIENPLSKLILEGRYAPKQTVHVLVKEGQIAFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZB6</accession>
    <name>A0A2S9GZB6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">GGDEF: diguanylate cyclase (GGDEF) domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2133</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93047">
        <property type="protein sequence ID" value="PRC93047"/>
        <property type="gene ID" value="S2091_2133"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013767">
        <property type="entry name" value="PAS_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00989">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PAS" evidence="1">
        <location>
            <begin position="15"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="2">
        <location>
            <begin position="183"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="320" mass="35552" checksum="84445D5C2469DBA6" modified="2018-07-18" version="1">MTKENVPAIQFDWAQLFEALNIGLILVDEQGCVLLWNEWITKHSGIHSDTVINKALINAFPEPLAGSFIAAINRALSTKLPVVLSNALHKFPLPLFNLNGSGERISQSIILSPLKNLHDQGKLMCLIQVNDSSTSIKREQMLRDHSETHKKDATTDPLTGIYNRRFFDAHYKLEISQAQRQKTTLSLIMLDIDYFKNYNDHYGHPAGDAAIIAVANCIKNKLQRSSDMAARYGGEEFIVLLPNSTSTAAQLFAEIIRQAVFDLKIPHLSSLTAKHLSVSIGVSSCPPGMIVDADTFLKNTDLALYAAKQKGRNQVQYLPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZF7</accession>
    <name>A0A2S9GZF7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Nucleotidyltransferase/DNA polymerase involved in DNA repair</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_2197</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA polymerase type-Y family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93111">
        <property type="protein sequence ID" value="PRC93111"/>
        <property type="gene ID" value="S2091_2197"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009432">
        <property type="term" value="P:SOS response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017961">
        <property type="entry name" value="DNA_pol_Y-fam_little_finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025188">
        <property type="entry name" value="DUF4113"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024728">
        <property type="entry name" value="PolY_HhH_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001126">
        <property type="entry name" value="UmuC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13438">
        <property type="entry name" value="DUF4113"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00817">
        <property type="entry name" value="IMS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11799">
        <property type="entry name" value="IMS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11798">
        <property type="entry name" value="IMS_HHH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="SSF56672"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50173">
        <property type="entry name" value="UMUC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0741">SOS mutagenesis</keyword>
    <keyword evidence="3" id="KW-0742">SOS response</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="UmuC" evidence="4">
        <location>
            <begin position="8"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC93111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="423" mass="47498" checksum="263ECEEAE9684A9E" modified="2018-07-18" version="1">MATLPRSIALVDCNNFYVSCERVFRPDLQNRPVLVLSNNDGCVVSRSNEAKEFGIKMAVPVFQIRDLVKQHGIAVFSSNYVLYADLSNRVMSILQEYSPVQEVYSIDETFLDLTGFTDINERALAMRNQVFQHIGIPVCVGIGPTKTLAKLANFVAKRHPRSNGVCNFNRYSPTQINSVLNNIPVDEVWGIGRKLSATLESLNINCVAQLRDANVASMRARFGVVMEKTIRELRGECCIDLEDATPAKKQIINSRSFGRSVTEIDDLQDALAHFVSNAAKKLREQESITAMLQVFIQTDRFRTDRSQYCPCVSIPLTSPTANTMKLQHWALGGLKSIYKTGYHYKKAGVILSEISAASHWQGDLFSSTTENSTLMRTLDALNDRYGKGTVKISQDGSRHSWKMRQESKSPEYTTNWHELPSCH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZI6</accession>
    <name>A0A2S9GZI6_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">tRNA-specific adenosine deaminase</fullName>
            <ecNumber evidence="3">3.5.4.33</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">tadA</name>
        <name evidence="5" type="ORF">S2091_2204</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>adenosine(34) in tRNA + H(+) + H2O = inosine(34) in tRNA + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:43168"/>
            <dbReference type="Rhea" id="RHEA-COMP:10373"/>
            <dbReference type="Rhea" id="RHEA-COMP:10374"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:82852"/>
            <dbReference type="EC" id="3.5.4.33"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="3">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the cytidine and deoxycytidylate deaminase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.33" evidence="3"/>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93118">
        <property type="protein sequence ID" value="PRC93118"/>
        <property type="gene ID" value="S2091_2204"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052717">
        <property type="term" value="F:tRNA-specific adenosine-34 deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002100">
        <property type="term" value="P:tRNA wobble adenosine to inosine editing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00972">
        <property type="entry name" value="tRNA_aden_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016192">
        <property type="entry name" value="APOBEC/CMP_deaminase_Zn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002125">
        <property type="entry name" value="CMP_dCMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028883">
        <property type="entry name" value="tRNA_aden_deaminase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14437">
        <property type="entry name" value="MafB19-deam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="SSF53927"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00903">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51747">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="2 3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CMP/dCMP-type deaminase" evidence="4">
        <location>
            <begin position="19"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="3">
        <location>
            <position position="72"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="70"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="100"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="103"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC93118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="174" mass="18577" checksum="1AABA6C868E479B8" modified="2018-07-18" version="1">MTQVFVTDSVINPLTDLVDQDAHFMRLAIAQAELAASAGEVPVGAVLVKDGVVIASGFNHPIGLHDPSAHAEMQALRAAGVELQNYRLPGCDLYVTLEPCAMCAGAMLHARLSRVIFGATDPKTGVAGSVFNLFEQEKLNHHTSLTGGVLAEECSNMLSSFFAQRRLQKKSTIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZJ3</accession>
    <name>A0A2S9GZJ3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">GGDEF: diguanylate cyclase (GGDEF) domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_2213</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93127">
        <property type="protein sequence ID" value="PRC93127"/>
        <property type="gene ID" value="S2091_2213"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="23"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="3">
        <location>
            <begin position="181"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC93127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="319" mass="35679" checksum="9167C1B0E6513F99" modified="2018-07-18" version="1">MINTPIDTFSASAQTGSTMNRQRLLIVDDQPLNIQTLYELFSANYQIFMATSGEQALSLCQSKLPDLIILDVEMPDMDGYEVCRRLKADVHTSNIPVIFITGHHNEAEETKGLDTGAVDFISKPINPRIVHARVKNQLMLKAQSDMLRDWVYIDGLTGVKNRRYFDERLNAEWGRAIRHNSELSIIIIDVDFFKLYNDCYGHLMGDDCLRLVANKLNSCINRSVDLMARYGGEEFVCLLPDTNLAGAMTVAEQLRQEVISLQIPHAVSKAAPFLTISLGVCTKQSMMVDSATSILTQADAELYLAKNQGRNHVCGKVMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZR4</accession>
    <name>A0A2S9GZR4_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF4382 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_1931</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93193">
        <property type="protein sequence ID" value="PRC93193"/>
        <property type="gene ID" value="S2091_1931"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025491">
        <property type="entry name" value="DUF4382"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14321">
        <property type="entry name" value="DUF4382"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015727828" description="DUF4382 domain-containing protein" evidence="2">
        <location>
            <begin position="21"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4382" evidence="3">
        <location>
            <begin position="45"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF14321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC93193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="589" mass="61600" checksum="4DDBAC495EC0D2DC" modified="2018-07-18" version="1">MQQKKLVQALVSIGLIGLLAACGGGGGSSGSSTGSSGTGVPTGTTGTVTMGVTDGPSDTFNHVWVTVTSISFHTSATQIWSKSDATWQTTTLPAPITIDLAALNNGALNNVFANMTLPVGTYKQIRFFFASDSDALSSSAQAISDNETTPTPLQWNDQVEYTNTRGTVSEAPLEIAYPTQGMQLLGTFNVTAGSATNLVTDFDLDKIIVPFNQDGQQAFTMRPDLRYFNLTQSGAITGTIDPTKLCQTVSTSNCAFNLIVHAETLSADGTRHVDVRSTNVDPVTGSFTLSPLSLVDSNNNPITYDIVVRGRNMETMLITGVTPTGTYTGTTVSGGAVLQSTPLEPTAATEYGTNLLTPLNPLTSGFAVFQQTLPSTAAIANPVPYEIRWSNTDPYTGVFYRAGCWNSNFMLTNGSISVAPYNAGNALVFTSVTPQEGNGGYSVATNEVVYYNLSNNLPLAAPTTGNISNFTPPTPTLDSGINPGSISGNIAISNASAYDHGTLVIARLGQIITSVDVSSLLSSGGGTFTVGNIPSGSATAAVPGAYYYSYIRLWKHNVNKHVKIVPITGSIDLRTTNSVTGMNVTVAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZZ4</accession>
    <name>A0A2S9GZZ4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2042</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93304">
        <property type="protein sequence ID" value="PRC93304"/>
        <property type="gene ID" value="S2091_2042"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="323" mass="37360" checksum="5131DD7EE8A07700" modified="2018-07-18" version="1">MNRQVIQGDGMEFKKWINKQRWCSKFTIITATFLALVTLQARAETLLIHPAAESAADPRYQYDWAVLRAAMDETVDTFGPYKIQEADELGMVQKRVDYEMQIPTGSINVFVRATSIDLEKLFLPIRIPVDRGILGYRVFLVRNADLPRFASVHKLDELRKFRFGQGKDWIDVQILTSAGFTVIEGTNYDGLFSMLTHLRFDIFSRSIDEAFSEYGKQQESNPTMSIEPSLVLHYPLPRYFFVRRDPQGKQLAKRIEKGMEKMVRDGSLVKLFFQFKKQQITQARLDKRAVLNISNPLLPPETPLSRRELWYDPLDPISASNKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H076</accession>
    <name>A0A2S9H076_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1772</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93385">
        <property type="protein sequence ID" value="PRC93385"/>
        <property type="gene ID" value="S2091_1772"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015590619" evidence="1">
        <location>
            <begin position="34"/>
            <end position="414"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="414" mass="44721" checksum="71E77F504822F75B" modified="2018-07-18" version="1">MTKFRYARFGVLIAALGLSAVSSMVPTAAFAQAAETVKPAIGTALHEASELAKAKKYKEALGKVRDADAVPGKTAYESYVIESTRGSYAMAAGDKETAVKAYEAVVSSGRLSGPQKLAMYESLGGSYYSMNNLPKASVWYGRYLSEGGDDPKIRAMMTQISFQNGDCSKVSKEISANVRAEEKAGRTPAEGDLQMLANCMKNDKAGYVGAMEKLTTYYPKKEYWKDLLNRLPARPGYSERLLLDVYRLKQDLGQLASVNDYMEMSQLSLQAGLPAEAQKIIDQGYKAGVFGVGPEAARHQRLKDLAAKNAAADLKALPQAEADANAAKEGTGLVNLGFAYVVSGQYPKGIALMEQGIAKDGLSRPDDAKLHLGIAYLWAGKKADAVKMFKTVEGKDGTADLARYWMIQANRPLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0A8</accession>
    <name>A0A2S9H0A8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ABC-type sugar transport system ATPase component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_1794</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93407">
        <property type="protein sequence ID" value="PRC93407"/>
        <property type="gene ID" value="S2091_1794"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015612">
        <property type="term" value="F:ABC-type L-arabinose transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042882">
        <property type="term" value="P:L-arabinose transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017917">
        <property type="entry name" value="ABC_transptr_Ara_ATP-bd_AraG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43790:SF6">
        <property type="entry name" value="PTHR43790:SF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="4" id="KW-1278">Translocase</keyword>
    <keyword evidence="8" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="7">
        <location>
            <begin position="5"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="7">
        <location>
            <begin position="253"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="37"/>
            <end position="44"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC93407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="496" mass="54729" checksum="7F6BF4FFBE4D2851" modified="2018-07-18" version="1">MTAYLQFDQVSKHFSGVRALAGVSFDAHAGTVHGLLGENGAGKSTLLKILGGQYRPDGGRLLVNSVPCQFNSAADAIRAGIAVIHQELQYVPELTVTENILMGRFPARFGLIDRNKARRMVLQRLSEIGVDLDPDARLSHLSIAQRQMVEICKAVMQNAQIIAFDEPTSSLSYTESEILFRLVRELRSTGHTLIYISHRLEELYSLCDACTIFRDGRKIVTHPVMAQVPRETLIHDMVGRELSDIYGYRPRPLGAQRLQVRGLRGKNDPTGCNFSVRGAEIVGFFGLVGAGRSELMRLLYGADRRLAGSVLLDGVPVPANSPPAAIEAGILLCPEDRKEQGILAQASVAENINISCRRHDLRVGFFLRRNKEAARADFFIDRLRIKTPNRDQEIRFLSGGNQQKVILARWLAESTMKVLILDEPTRGIDVGAKNEIYRIIQEVAEQGCCVIVVSSELPEVLGIADRVLVMRNKEISGVLDRSEATETAVLNLALAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0D4</accession>
    <name>A0A2S9H0D4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Phage tail sheath protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_1829</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the myoviridae tail sheath protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93442">
        <property type="protein sequence ID" value="PRC93442"/>
        <property type="gene ID" value="S2091_1829"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035089">
        <property type="entry name" value="Phage_sheath_subtilisin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020287">
        <property type="entry name" value="Tail_sheath_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04984">
        <property type="entry name" value="Phage_sheath_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17482">
        <property type="entry name" value="Phage_sheath_1C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phage_sheath_1" evidence="2">
        <location>
            <begin position="301"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="domain" description="Phage_sheath_1C" evidence="3">
        <location>
            <begin position="399"/>
            <end position="503"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC93442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="508" mass="56022" checksum="6B0FFF47C398751C" modified="2018-07-18" version="1">MAGAYKTPGVYIVEKNAFPNSVVEVATAVPAFIGYTKIADNKGTSLTNKPWRITSLTEFINYFGDAPEDRFDIAEKTDADLTSDFKSGGKEFVLKRENNKADTKRYYLYRCMQLFFQNGGSPCYIVSIGGYSGDGVQRKPMELGIDLLLKEQEPTMVVIPDAVALDEGDCIGLQQYSLKHCGFQMKNRFAILDVYDGFRERSDPTGDCVTKFRADLGTNFLNYSAAYYPWLNTSIVQTTDLDFSSFVSLENVKNLLLTEAGGDTAPQDIKDILAQVGKADRDPKEKTYLSDDELHKILFSVSPTYANMLLAIKNKLNLLPPAAAMAGVYTMVDNARGVWKAPANVSLASVISPAVNITHDEQEDLNVTTAGKSINAIRSFIGEGTLVWGARTLDGNSLDWRYINVRRTMIMLEESLRLATKAYVFEPNVSGTWVTISSMASNFLTGIWKRGGLAGASPEDAFSVHVGLGETMTAEDILEGILRVTILVALSRPAEFIEITFQQQMQKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0I2</accession>
    <name>A0A2S9H0I2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phosphate acetyl/butaryl transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1855</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93468">
        <property type="protein sequence ID" value="PRC93468"/>
        <property type="gene ID" value="S2091_1855"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005835">
        <property type="term" value="C:fatty acid synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004312">
        <property type="term" value="F:fatty acid synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003965">
        <property type="entry name" value="Fatty_acid_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002539">
        <property type="entry name" value="MaoC-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002505">
        <property type="entry name" value="PTA_PTB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01575">
        <property type="entry name" value="MaoC_dehydratas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01515">
        <property type="entry name" value="PTA_PTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01483">
        <property type="entry name" value="FASYNTHASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="MaoC-like" evidence="2">
        <location>
            <begin position="18"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="domain" description="PTA_PTB" evidence="1">
        <location>
            <begin position="236"/>
            <end position="451"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="462" mass="49261" checksum="326AAD585D640F47" modified="2018-07-18" version="1">MDRIENRTFDEIEVGETARLTRTLTHKDIELFAIVSGDVNPAHVDAEFARSDMFHKVIAHGMWGGALISTVLGTELPGPGTIYLNQTLSFRNPVALGDTVTVVVTVSDKIEKGHRIALDCLVTNQRGETVISGKAEVVAPTEKVSRKRIVLPEVEFREKGRGYRRLIEMTSGMVPLRTAVVHPVDTNSLVGAVEAAHEGLIVPILVGPEAKIRAAAKLAAIDLSAFEIIDALHSDDAAAKAVALARSGKVEALMKGALHTDELLHAVVDRETGLRTERRMSHVFAIDAPGYPRPLFITDAAINVYPTLEDKRDIVQNAIDLAHALGIPQPKVALLSAVETVTPLIKSTLDAAALCKMADRGQITGGILDGPLAFDNAVSIEAAKTKGIVSAVAGVADIFVVPDLEAGNMLAKQLEYLADADVAGIALGARVPIILTSRADKTLSRLGSCAIALLLARHKEKC</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0K9</accession>
    <name>A0A2S9H0K9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1885</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93498">
        <property type="protein sequence ID" value="PRC93498"/>
        <property type="gene ID" value="S2091_1885"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="186" mass="21271" checksum="7B6B358C49EA2AE2" modified="2018-07-18" version="1">MKQTKASAEWSKNFPNAAPAGFLCRDAYADRWLRIHSLPESKRYAESESERLELLRRHNTVASDILGEDSDCILFLGQFGSDKIWQDDLDTPLNGILPVYAMTYEYDDDEWQFFSVPVRWQRARFDDLILAKANDLTGPVMFANTKLGTAYSPYDGGADLFYSMQSNLERAKLNYSAWLSGRDNSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0P8</accession>
    <name>A0A2S9H0P8_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Transport permease protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_1552</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell inner membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the ABC-2 integral membrane protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93551">
        <property type="protein sequence ID" value="PRC93551"/>
        <property type="gene ID" value="S2091_1552"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC_2_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000412">
        <property type="entry name" value="ABC_2_transport"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006648">
        <property type="entry name" value="DrrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00164">
        <property type="entry name" value="ABC2TRNSPORT"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51012">
        <property type="entry name" value="ABC_TM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="48"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="89"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="128"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="163"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="199"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="252"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="domain" description="ABC2_membrane" evidence="7">
        <location>
            <begin position="31"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC93551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="284" mass="31946" checksum="D55D0CEF0E05D42C" modified="2018-07-18" version="1">MTLSSIAINPHANQPVSFTSLLKSLWHNRQLIFQMSKREVIGRYRGSALGLAWSFFNPVFMLIVYTFVFSEIFKSRWGGMSASGSKTEFAVVLFVGLIVQGLFAEMLNRAPSLILSNVNYVKKVVFPLEILPVIALGSTLFHCMVSITVWLIAFVAFNGYLHWTIVFIPLVLLPMIILITGLAWILASLGVYLRDIGQTIIILTTVLMFLAPIFYPVIAVPEQFRPFIMANPLTFIIEQARDVLVWGVQPNWVGLGVYALVALIIFWAGYTFFQKTRKGFADVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0T1</accession>
    <name>A0A2S9H0T1_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_1590</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93589">
        <property type="protein sequence ID" value="PRC93589"/>
        <property type="gene ID" value="S2091_1590"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="29"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="266"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="6">
        <location>
            <begin position="301"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="7">
        <location>
            <begin position="376"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="5">
        <location>
            <begin position="448"/>
            <end position="663"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC93589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="670" mass="75728" checksum="4A7EF7F31CFBE43B" modified="2018-07-18" version="1">MPILKLPKPITIVDNHISRTRSPFIKQHWVPPILLAILLLPVLILLPWRSQKIEFEDRQQQLIADTLWVEQGIRFQLIRNEDSLRVLGDDIIANSVAPEQLKARFSALIQKHPELHQLIWLDAKDQVRFSTRPFTPADFSLYSKQAIVHARSSETPQYAQPATQEGEDSVILMDYHLPLFRHNRYIGSLVVSYEMSEILEKLVPWWFAKDNEISLTDIDDIVFAMRADGGYGHNVYTHSRNLDLSGVNLILKINSIKSTPRLLSNYLVAAVVLLGLGLVWSLWALWRDILRRQAAETALREQMAFRSAMEKSLVTGLRVRSLDGRLVYVNPAFCDMVGYTEQQLVGQKAPLPFWAAEAIDSYQKRLPIMGKNMSLSGFETVYKHADGHLIPVLIYESALLDDDGMQTGWMGSILDISDRKQAEQILRQHEERLESSARLSTMGELASVMAHELNQPLAAISSYATGALNMMKMGDVEPSVLQPALIQMQNQAQRAGQIIRSVHDFVVKREPNRTQMQLKAVFNSVLPLIELQAKSYLINVQIYIEHPLPDVLVDSISLEQVILNLTRNALQAMQELTLQQRILQIEVKKYGNYVQVEVIDHGAGMDQDVVDRLFSPFFSTKAEGMGMGLNICRTIIEFHGGQLTFRANPTGGTIFCFTLPAIESSSTIEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0T4</accession>
    <name>A0A2S9H0T4_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 11">Tyrosine recombinase XerD</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">xerD</name>
        <name evidence="15" type="ORF">S2091_1593</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the 'phage' integrase family. XerD subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93592">
        <property type="protein sequence ID" value="PRC93592"/>
        <property type="gene ID" value="S2091_1593"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009037">
        <property type="term" value="F:tyrosine-based site-specific recombinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01808">
        <property type="entry name" value="Recomb_XerC_XerD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01807">
        <property type="entry name" value="Recomb_XerD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044068">
        <property type="entry name" value="CB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002104">
        <property type="entry name" value="Integrase_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010998">
        <property type="entry name" value="Integrase_recombinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004107">
        <property type="entry name" value="Integrase_SAM-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011932">
        <property type="entry name" value="Recomb_XerD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023009">
        <property type="entry name" value="Tyrosine_recombinase_XerC/XerD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02899">
        <property type="entry name" value="Phage_int_SAM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00589">
        <property type="entry name" value="Phage_integrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02225">
        <property type="entry name" value="recomb_XerD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51900">
        <property type="entry name" value="CB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51898">
        <property type="entry name" value="TYR_RECOMBINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 11" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="5 11" id="KW-0132">Cell division</keyword>
    <keyword evidence="6 11" id="KW-0159">Chromosome partition</keyword>
    <keyword evidence="4 11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 11" id="KW-0229">DNA integration</keyword>
    <keyword evidence="9 11" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="8 11 12" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core-binding (CB)" evidence="14">
        <location>
            <begin position="5"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="domain" description="Tyr recombinase" evidence="13">
        <location>
            <begin position="111"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="151"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="175"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="246"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="249"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="272"/>
        </location>
    </feature>
    <feature type="active site" description="O-(3'-phospho-DNA)-tyrosine intermediate" evidence="11">
        <location>
            <position position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="PRC93592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="300" mass="34225" checksum="6CE8E3B63CE376DD" modified="2018-07-18" version="1">MVINPLMQSEIDEFCDTLWLEDGLSKNTLEAYRRDLTLFAKWRTSKEHDSLINASAAEINQYTSYLHESSKATTANRRLAVFKRFYQHALRQQKIKADPTLKIASAKTPTRNIQTLSEAQVEALLAAPNHSTELGLRDRCMLELMYASGLRVTELVLLKMQEVSLNDNVLRITGKGDKTRLVPFGEIASSWISRYLKEARPLIMKGQIDDALFVTARGGAMTRQMFWIMIKKYSLQAEINAPLSPHTLRHAFATHLINHGADLRVVQLLLGHSDITTTQIYTHVARERLKRLHKEHHPRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0V0</accession>
    <name>A0A2S9H0V0_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">tRNA-specific 2-thiouridylase MnmA</fullName>
            <ecNumber evidence="7">2.8.1.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">mnmA</name>
        <name evidence="8" type="ORF">S2091_1615</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>AH2 + ATP + S-sulfanyl-L-cysteinyl-[protein] + uridine(34) in tRNA = 2-thiouridine(34) in tRNA + A + AMP + diphosphate + H(+) + L-cysteinyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:47032"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11726"/>
            <dbReference type="Rhea" id="RHEA-COMP:11727"/>
            <dbReference type="Rhea" id="RHEA-COMP:11728"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61963"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:87170"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.8.1.13"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the MnmA/TRMU family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.13" evidence="7"/>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93614">
        <property type="protein sequence ID" value="PRC93614"/>
        <property type="gene ID" value="S2091_1615"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016783">
        <property type="term" value="F:sulfurtransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01998">
        <property type="entry name" value="tRNA_Me_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.280">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00144">
        <property type="entry name" value="tRNA_thiouridyl_MnmA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023382">
        <property type="entry name" value="Adenine_a_hdrlase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004506">
        <property type="entry name" value="tRNA-specific_2-thiouridylase"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00420">
        <property type="entry name" value="trmU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 7 8" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 7" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="2 7" id="KW-0820">tRNA-binding</keyword>
    <feature type="region of interest" description="Interaction with target base in tRNA" evidence="7">
        <location>
            <begin position="95"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Interaction with tRNA" evidence="7">
        <location>
            <begin position="146"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Interaction with tRNA" evidence="7">
        <location>
            <begin position="312"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="7">
        <location>
            <position position="100"/>
        </location>
    </feature>
    <feature type="active site" description="Cysteine persulfide intermediate" evidence="7">
        <location>
            <position position="196"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="9"/>
            <end position="16"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="35"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="124"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="site" description="Interaction with tRNA" evidence="7">
        <location>
            <position position="125"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with tRNA" evidence="7">
        <location>
            <position position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC93614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="363" mass="40089" checksum="2D9951EFE9C7AF9E" modified="2018-07-18" version="1">MAKKRVVIGMSGGVDSSVSAHLLKEQGYEVIGLFMKNWEDDDNSEFCSSRQDWIDAVSVADVVGVDIEAVNFAAEYKDRVFSEFLREYQAGRTPNPDVLCNAEIKFKAFLDHAMHLGADFIATGHYARVREVDGRFELLKALDLSKDQSYFLHRLNQAQLCKTLFPLGEIHKTEVRKIAEQLQLPNATKKDSTGICFIGERPFREFLNRYLVQKPGPMKTPEGELVGQHIGLSFYTLGQRKGIGIGGIKSHQNAEGSSDAWYVARKDIANNTLYVVQGHDHPWLLSPTLAADQASWVAGSPPETGQLNAKTRYRQADVAGLFEATGANQFNLAFTDPQWAVTPGQSAVLYQGDVCLGGGIICS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0W1</accession>
    <name>A0A2S9H0W1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative heme degradation protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1626</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93625">
        <property type="protein sequence ID" value="PRC93625"/>
        <property type="gene ID" value="S2091_1626"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006826">
        <property type="term" value="P:iron ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007845">
        <property type="entry name" value="HemS/ChuX_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05171">
        <property type="entry name" value="HemS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HemS" evidence="1">
        <location>
            <begin position="42"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="domain" description="HemS" evidence="1">
        <location>
            <begin position="226"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="358" mass="40442" checksum="ED1E2A5B28ACF8EF" modified="2018-07-18" version="1">MQSNVQKNYSESSDLSTDLQARYQKLKQQTKIRVRDAAQQLGVSEAELVASGMNENVIRLDGPFHDLMARIHELGTVMALTRNESVVHEKDGIYLNMSCQGEVGMALGAEIDLRIFYRHWHHGFAVIDMLETEHETRAQRSLQFFDAQGTAVHKIYLRNHSNVTAFSQLVSDFASQDQTSQLAILPAAVKSRIKPDQEIDVDGLRAAWSSMQDTHEFFGLLKKFEADRHQALRLTKTEFAYQVSLSSVRLLLQTVAMRATPIMVFVGNQGMIQIHSGPIQNVKVMDSWLNILDPGFNLHLREDDIASVWVVKKPTADGIVTSLELFNADNENITMFFGQRKPGKPELTEWQDAINELS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H108</accession>
    <name>A0A2S9H108_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyl transferase family 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1547</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93546">
        <property type="protein sequence ID" value="PRC93546"/>
        <property type="gene ID" value="S2091_1547"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="2">
        <location>
            <begin position="13"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="322" mass="37130" checksum="EDB93645817D26D7" modified="2018-07-18" version="1">MNEMNKPHEIKLSVLLVTYNHKKYLNQALQSLFQQNICGVVELVIADDCSQDSTLDIIKSYEGKNNQFIFKYLDNTKNLGITKNYQRAFSACSGEYVAVLEGDDYWVSPFKLQRQIEFLDTHWECDLCSVNYFVYEENRNLFYPRVAISNNHRLVTARDLIADNLVGNFSTCMYRKSALENLPEELFNICSYDWIVNICIAKKSMIGFLEQPMSVYRVHSNGVWSQTPHIEQLKLQLELIPSYDALTQHIYHAEFENLSNHLTNMIAKSNFIHVVSTAINPPAGLLAQVVDWLPPFVMGLMRGLIPPNLKKYIVNFFHRGAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1H3</accession>
    <name>A0A2S9H1H3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cation/multidrug efflux pump</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1438</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93829">
        <property type="protein sequence ID" value="PRC93829"/>
        <property type="gene ID" value="S2091_1438"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2090.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027463">
        <property type="entry name" value="AcrB_DN_DC_subdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001036">
        <property type="entry name" value="Acrflvin-R"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32063">
        <property type="entry name" value="PTHR32063"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00873">
        <property type="entry name" value="ACR_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00702">
        <property type="entry name" value="ACRIFLAVINRP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82714">
        <property type="entry name" value="SSF82714"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="334"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="360"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="431"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="463"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="529"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="858"/>
            <end position="876"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="909"/>
            <end position="934"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="954"/>
            <end position="975"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="987"/>
            <end position="1013"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1023"/>
            <end position="1054"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="1054" mass="113861" checksum="B5E7873DC365348B" modified="2018-07-18" version="1">MNLSRPFIERPVATALLMVALLLVGLMAYRLLPLSALPEVDYPTIQVVTLYPGASPEVITSSITAPLERQFGQMPGLNQMSSSSSGGASVITLQFSLALSLDVAEQEVQASINAAGNLLPVDIPAPPIYNKVNPADTPIMTLALTSKTLPLPQVQSFADTRLAQKISQVSGVGLVSISGGQRPAVRVQVNPTALASYGLNIEDVRTAIGAANVNQAKGSFDGPARAFTIDANDQLKSAAEYRDVFVAYRNNAPVRLSDVADVIEDAENVKLAAWVNDKPAIILNIQRQPGANVIDVVDHVKQLLPRLKAAIPAGIEVSILSDRTDTIRSSVKDVQFELMLSVALVVMVIFLFLRNLAATIIPSVAVPLSVIGSFSVMYLAGFSLNNLSLMALTISTGFVVDDAIVMIENIARYIEEGEEPLAAAIKGSKQIGFTILSLTISLIAVLIPLLFMGDIVGRLFREFAITLSVTIVISAIVSLTLTPMMCAKLLRHTPEDQQSRFYHASGQFYERVIERYGVWLNWVLERQTATLLVAIGTLVLTVLLYIVVPKGFFPLQDTGVIQGISEAPQSISFPAMADRQQALAKVILQDPEVESLSSFIGVDGVNTTLNSGRIQINLKPHDDREHSAAEIIQRLQKKLADVEGISLYMQPVQDLTIETRVSRTQYQFSVEDADPEQLSTWTPKLVEVLNKLPELRDVASDLQDQGLQVALTIDRSTAARMGITPTAIDSTLYSAFGQRIVSTIFTQTNQYRVILEVKPEFQISPAALKNIYISGTNDTQVPLSAIASITEKHTPLVINHIGQFPANTVSFNLAPGVSLGQAVEAINKAKLAVNLPASTQINFQGAAQAFNASLGNELLLILAAIVTVYIVLGVLYESYIHPITILSTLPSAGMGALLALMAFGSDLGIIAVIGIILLIGIVKKNAIMIIDFALDAERNQNMSPRDAIYQACLLRFRPIMMTTMAALLGALPLMLGGGVGSELRHPLGITIVGGLIVCQVLTLFTTPVIYLAFDRLARRINPQASSRLEENEEEEQPDELETKLPTQLPPARPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1J9</accession>
    <name>A0A2S9H1J9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Efflux transporter, RND family, MFP subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_1439</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93830">
        <property type="protein sequence ID" value="PRC93830"/>
        <property type="gene ID" value="S2091_1439"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039562">
        <property type="entry name" value="MFP_biotin_lipoyl_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006143">
        <property type="entry name" value="RND_pump_MFP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13533">
        <property type="entry name" value="Biotin_lipoyl_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01730">
        <property type="entry name" value="RND_mfp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="21"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="domain" description="Biotin_lipoyl_2" evidence="4">
        <location>
            <begin position="96"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="394"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="423"/>
            <end position="439"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC93830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="439" mass="45984" checksum="F8D0088B28A7E6B9" modified="2018-07-18" version="1">MNKITPSSTNSSPSTKSSNKWLWLLALVIIAGAGAVYFSKSAKSAKDGGAASASADGGKHGGANAAKPIPVVTALAKTDDINVYLNGLGTVTPLATVTVKSRIDGEIMKIYFTEGQMVKRGDVLAEIDPRPYQAAWTQAEGQLMRDKALLANARIDLERYRTLLKQDSIASQQVDTQLALVDQYEGTVKVDEGLLATAKLNLVYSKVTAPVSGRAGLRQVDLGNVIHASDSTGIVIITQLQPMSVLFTLPEDSIPALLKNLQSGKKIAVDAYDRAFKEKITSGGLQTIDNQIDPTTGMVKLKAEFANTDLNLFPSQFVNAKLLLETKHNVITVPSSAIQRGRSSSFAFVVAADSTVSQHTVVVGTTQGDKTEVVSGLQSGDIVVIDGADKLRDGAKVDTASNTDAAKGDKGSKDGSGKHKHAASASASASSSSSASAPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1V1</accession>
    <name>A0A2S9H1V1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aerobic-type carbon monoxide dehydrogenase small subunit CoxS/CutS-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1110</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC93937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93937">
        <property type="protein sequence ID" value="PRC93937"/>
        <property type="gene ID" value="S2091_1110"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002888">
        <property type="entry name" value="2Fe-2S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036884">
        <property type="entry name" value="2Fe-2S-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00111">
        <property type="entry name" value="Fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01799">
        <property type="entry name" value="Fer2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47741">
        <property type="entry name" value="SSF47741"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="SSF54292"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="1">
        <location>
            <begin position="6"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="183" mass="20167" checksum="692C82AD182A15FD" modified="2018-07-18" version="1">MSRTIYPITLHINGKPVGPVPVPEGIMMIDFLHEYLDLTGSRLGCGQGICHACVVILDKPDGSSEEVRSCITGAHFFDGKQIRTVEGHAQRNEQGEVVTLSPVQQKFLEHYSFQCGYCTPGFVNAATVLLEKLKRHPVSRAQLDQAITDGLNHHICRCTGYVRYFEAVKEVALSTAGLVKDVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2B9</accession>
    <name>A0A2S9H2B9_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 2">50S ribosomal protein L24</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">rplX</name>
        <name evidence="3" type="ORF">S2091_1304</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.</text>
    </comment>
    <comment type="function">
        <text evidence="2">One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the universal ribosomal protein uL24 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94131">
        <property type="protein sequence ID" value="PRC94131"/>
        <property type="gene ID" value="S2091_1304"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06089">
        <property type="entry name" value="KOW_RPL26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01326_B">
        <property type="entry name" value="Ribosomal_L24_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041988">
        <property type="entry name" value="KOW_RPL26/RPL24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_L2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003256">
        <property type="entry name" value="Ribosomal_L24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005825">
        <property type="entry name" value="Ribosomal_L24/26_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12903">
        <property type="entry name" value="PTHR12903"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17136">
        <property type="entry name" value="ribosomal_L24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="SSF50104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01079">
        <property type="entry name" value="rplX_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01108">
        <property type="entry name" value="RIBOSOMAL_L24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 3" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00029550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="104" mass="11104" checksum="555B042F47F1507E" modified="2018-07-18" version="1">MNKIRKNDEVIVLTGKDKGKRGQVQQWIDADHVVVAGVNIAKKAVKPNPMTGATGGIVDKVMPIHVSNVALFNAATGKADRVGFKVVDGVKVRVFKSNGEVVKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2K9</accession>
    <name>A0A2S9H2K9_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Methyltransferase</fullName>
            <ecNumber evidence="4">2.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_0846</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the N(4)/N(6)-methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="4"/>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94225">
        <property type="protein sequence ID" value="PRC94225"/>
        <property type="gene ID" value="S2091_0846"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008170">
        <property type="term" value="F:N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006306">
        <property type="term" value="P:DNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002941">
        <property type="entry name" value="DNA_methylase_N4/N6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001091">
        <property type="entry name" value="RM_Methyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01555">
        <property type="entry name" value="N6_N4_Mtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00508">
        <property type="entry name" value="S21N4MTFRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N6_N4_Mtase" evidence="5">
        <location>
            <begin position="41"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU362026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC94225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="301" mass="34126" checksum="4D5B33ACD87A67BB" modified="2018-07-18" version="1">MNRSSFKASLILPKAPMSHYINTVFNEDALEGFKRIPDASIDLIIADPPYSLGKDYGNESDKLATGDYLQWMENWIDAVLPKLKPSGSFYIFLTWRYSPEIFVMLKQRMQMMNEIIWDRRVPSMGGSVRSFSSVHDTIGFFVKEKGYYFDLDAVRIPYDAVTKKARSRSIFVGAKWLEVGYNPKDLWSVSRVHKSDPERADHPTQKPLEIIDRMIHASCPPGGLVLDPFMGSGTTAVSAQRCGRNFVGFELNSSYCEIIQQRLAAPEAQLVMRNNHPTEPIRAKVKKERIIKKAPSSPQAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H318</accession>
    <name>A0A2S9H318_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Type II secretion system protein I</fullName>
            <shortName evidence="5">T2SS minor pseudopilin I</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_0981</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Type II secretion is composed of four main components: the outer membrane complex, the inner membrane complex, the cytoplasmic secretion ATPase and the periplasm-spanning pseudopilus.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell inner membrane</location>
            <topology evidence="5">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="5">Cleaved by prepilin peptidase.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the GSP I family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94360">
        <property type="protein sequence ID" value="PRC94360"/>
        <property type="gene ID" value="S2091_0981"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015627">
        <property type="term" value="C:type II protein secretion system complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015628">
        <property type="term" value="P:protein secretion by the type II secretion system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003413">
        <property type="entry name" value="T2SS_GspI_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010052">
        <property type="entry name" value="T2SS_protein-GspI"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38779">
        <property type="entry name" value="PTHR38779"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02501">
        <property type="entry name" value="T2SSI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01707">
        <property type="entry name" value="gspI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0488">Methylation</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="21"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="domain" description="T2SSI" evidence="6">
        <location>
            <begin position="59"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU368030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC94360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="141" mass="15653" checksum="DD9A55A4AF1F6012" modified="2018-07-18" version="1">MVIFRTGDLEQQRYPQTYKRYKASGFTLLEVLVALVIVGTALSASLRAVSNLTRNSGALHASTMGSWSAENTLVNLRLSKVWPDVGKQSINCPQDDMQLVCEQSVTASNNPNFRRVEINVYDAQDTQRRVAHLVQLVSNGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H319</accession>
    <name>A0A2S9H319_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Phage tail sheath protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_0992</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the myoviridae tail sheath protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94371">
        <property type="protein sequence ID" value="PRC94371"/>
        <property type="gene ID" value="S2091_0992"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035089">
        <property type="entry name" value="Phage_sheath_subtilisin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020287">
        <property type="entry name" value="Tail_sheath_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04984">
        <property type="entry name" value="Phage_sheath_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17482">
        <property type="entry name" value="Phage_sheath_1C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phage_sheath_1" evidence="2">
        <location>
            <begin position="329"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="domain" description="Phage_sheath_1C" evidence="3">
        <location>
            <begin position="414"/>
            <end position="520"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC94371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="526" mass="56296" checksum="1FB867B573CA8189" modified="2018-07-18" version="1">MTTSLSTPGVYINEINGFPNSVVPVETAVPAFIGYTAAAAYLGKSYFNIPSLITSFAEFQAIFMLPDPPPPADPAKQYNPEYYLVAQIGVPTAGDYVLIDGVYYSVLPDPNTIYYMYNSVRLFFQNGGANAYIVSVGTYGPPSGKPVSGPNVNVVNPNVQLSDLQRGLSLLLNEMEPTMYICPDATLLSLPDNEKLMQSMLLQAAKMQTAVCLLDVIGGVNPDPIMYTTNIQNFRNSTGSLGLNYGISYYPFIGTTIMQSGDVDFTNLFGGDIKQLAAILNPPSNPNPVAGQILSMIETPPSDPKTNSQLQADLIDASPLYSKIINLVLAEANILPPSGAMAGVYTVNDNMAGVWNSPANTSIVGAVSLPINLSDSQQANLNVDAVSGKSINAIRSFPGQGILIWGARTLDGNSQDWRYLSVRRMMIFLEQSIKLAARSYVFEPNDANTWAAIKSTVDSFLTSVWKEGGLIGATPADAFNVSVGLGTTMTGDDVLNGILNVTVQVCVVHPAEFITITFQQVQANSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3E8</accession>
    <name>A0A2S9H3E8_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Phosphogluconate dehydratase</fullName>
            <ecNumber evidence="6">4.2.1.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">edd</name>
        <name evidence="7" type="ORF">S2091_0493</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the dehydration of 6-phospho-D-gluconate to 2-dehydro-3-deoxy-6-phospho-D-gluconate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>6-phospho-D-gluconate = 2-dehydro-3-deoxy-6-phospho-D-gluconate + H2O</text>
            <dbReference type="Rhea" id="RHEA:17277"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:57569"/>
            <dbReference type="ChEBI" id="CHEBI:58759"/>
            <dbReference type="EC" id="4.2.1.12"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="6">Binds 1 [4Fe-4S] cluster.</text>
    </comment>
    <comment type="pathway">
        <text evidence="6">Carbohydrate metabolism; Entner-Doudoroff pathway.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the IlvD/Edd family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.12" evidence="6"/>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94490">
        <property type="protein sequence ID" value="PRC94490"/>
        <property type="gene ID" value="S2091_0493"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00226"/>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004456">
        <property type="term" value="F:phosphogluconate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046177">
        <property type="term" value="P:D-gluconate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009255">
        <property type="term" value="P:Entner-Doudoroff pathway through 6-phosphogluconate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02094">
        <property type="entry name" value="Edd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004786">
        <property type="entry name" value="6-phosphgluc_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042096">
        <property type="entry name" value="Dihydro-acid_dehy_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000581">
        <property type="entry name" value="DiOHA_6PGluconate_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020558">
        <property type="entry name" value="DiOHA_6PGluconate_deHydtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037237">
        <property type="entry name" value="IlvD/EDD_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43661:SF1">
        <property type="entry name" value="PTHR43661:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00920">
        <property type="entry name" value="ILVD_EDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143975">
        <property type="entry name" value="SSF143975"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01196">
        <property type="entry name" value="edd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00886">
        <property type="entry name" value="ILVD_EDD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00887">
        <property type="entry name" value="ILVD_EDD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="5 6" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="3 6" id="KW-0311">Gluconate utilization</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4 6" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="6">
        <location>
            <position position="165"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="232"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC94490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="618" mass="65761" checksum="87CA9E89443DE8F9" modified="2018-07-18" version="1">MTAITPSALTPIHPVIEQVTERIRVRSLTLRTAYLARIEQFRGRPPRRAQLSCANQAHANAAAESRAKIWLNQAQKPNIGIVTAYNDMLSAHQPYASYPDQIKAAALRFGATAQVAGGVPAMCDGVTQGRPGMELSLFSRDVIAQATAVALSHDAFDAALCLGICDKIVPGLLIGALAFGHLPTIFIPAGPMGSGLSNKDKAAVRERFAQGKATKEELLAAESAAYHSAGTCTFYGTANSNQMLLEAMGLHLPGAAFIHPGTALRHALTDAAVEQVIQLTEQGNHYTPIGHVVNEKSIVNAIIALLATGGSTNHTMHWIAVARAAGILIDWQDFDELSAVIPLLTRIYPNGSADVNEFEDAGGPVFVIRELLAAGLMHGDVQTVFGTTGLYAHTRQPELQNEVLSWRDLPEQSTNTGVVRKVSEPFAATGGLRLLQGNLGRAIIKASAVPAEAWTIRAPAKVFESQDALVSAFKAGQLNMDFVAVVIFQGPQANGMPELHHFTPVLGSLMSAGFKVALVTDGRMSGASGKVPAALHISPEAAQGGALARVQDGDMVELDVAEGRLHVDVPEAEFAARIPRVLRAAHLDDTVDFGRELFVNQRRFVTAPEHGASTLFKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3Z9</accession>
    <name>A0A2S9H3Z9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Peptidase family M28</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_0599</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Golgi apparatus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Lysosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94596">
        <property type="protein sequence ID" value="PRC94596"/>
        <property type="gene ID" value="S2091_0599"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005764">
        <property type="term" value="C:lysosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070573">
        <property type="term" value="F:metallodipeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039866">
        <property type="entry name" value="CPQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007484">
        <property type="entry name" value="Peptidase_M28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12053">
        <property type="entry name" value="PTHR12053"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04389">
        <property type="entry name" value="Peptidase_M28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_M28" evidence="7">
        <location>
            <begin position="289"/>
            <end position="475"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC94596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="498" mass="54152" checksum="000333A3A5A12F32" modified="2018-07-18" version="1">MQAQSKASASLPYKNSLQTQAKDAMNFFSRKPLMGVLLASLLMHASLVHSQIGTAQLTELPSSAPTSILIKEIADHAELMKNLETICDDVGPRLTGSQQLRTAQAWAMEKLNAYGAVDVHEEAYDLGRPWQRGIARAHLVNANGIALDIVQKAWTVGTNGVIRADVALLDVKTLDEFNAVAPTLRGKIVLVISGPKATPEQNKNIKQYSAEVNRAIHEAHFAAVLLTSDKDNGLQNMWGSPSSRFDRNAGIITSENANLLKRLLARGITPKLEMELTGNFSKESVKAYNVVADFKGTEAADEMVIIGAHLDSWDLGTGATDNGTGVVVAMEILRAMHAQGLHPKRSLRVVLFSGEEQGLLGSKAYLVKHREELAKIQAIIVQDAGSGRIMGFPDMKVEAWYTALTAAIAPAKELGAQDVIYAIGNGSDHDVFFEQGIPAFTPMQDPLDYRSHTHHSQVDTVDHVVLADLMQSAQVMAITVWGLLNGERLPHQEQSEKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H412</accession>
    <name>A0A2S9H412_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Probable 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase</fullName>
            <shortName evidence="2">2-(5''-triphosphoribosyl)-3'-dephospho-CoA synthase</shortName>
            <ecNumber evidence="2">2.4.2.52</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">mdcB</name>
        <name evidence="3" type="ORF">S2091_0722</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Involved in the formation of 2-(5''-phosphoribosyl)-3'-dephosphocoenzyme-A, the prosthetic group of the acyl-carrier protein of the malonate decarboxylase.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 2">
            <text>3'-dephospho-CoA + ATP = 2'-(5''-triphospho-alpha-D-ribosyl)-3'-dephospho-CoA + adenine</text>
            <dbReference type="Rhea" id="RHEA:15117"/>
            <dbReference type="ChEBI" id="CHEBI:16708"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57328"/>
            <dbReference type="ChEBI" id="CHEBI:61378"/>
            <dbReference type="EC" id="2.4.2.52"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CitG/MdcB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.52" evidence="2"/>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94719">
        <property type="protein sequence ID" value="PRC94719"/>
        <property type="gene ID" value="S2091_0722"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046917">
        <property type="term" value="F:triphosphoribosyl-dephospho-CoA synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01883">
        <property type="entry name" value="MdcB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002736">
        <property type="entry name" value="CitG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017555">
        <property type="entry name" value="TriPribosyl-deP-CoA_syn"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30201">
        <property type="entry name" value="PTHR30201"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01874">
        <property type="entry name" value="CitG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03132">
        <property type="entry name" value="malonate_mdcB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="303" mass="32600" checksum="4C5828631FF7F6B1" modified="2018-07-18" version="1">MVEIYQVIESNALAEKLADMVIAALIDEATLTPKPGLVDMRSRGAHYDMSWSLMCDSALALRPTFYAMADAGMQRYPQRQLREIIGALGRAGEVRMMEVSNGVNTHRGAIWALGLLVTAAAQNLSALSVNAITECAARLAQIDDQFAPKFTGNKGEQACFRYQVGGARAQAQTGFPFVVDHALPTLHRSRKQGDKETCAQLNALLSIMAVLDDTCILSRGGTSALTSVQIGARKVLELGGVTTAPGKAALHNLEADMLRRHVSPGGSADMLAAALFVDNLTKQPKWLSSKFVDSDNQIQTIGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H443</accession>
    <name>A0A2S9H443_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Bifunctional protein GlmU</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="15">UDP-N-acetylglucosamine pyrophosphorylase</fullName>
                <ecNumber evidence="15">2.7.7.23</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="15">N-acetylglucosamine-1-phosphate uridyltransferase</fullName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="15">Glucosamine-1-phosphate N-acetyltransferase</fullName>
                <ecNumber evidence="15">2.3.1.157</ecNumber>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name evidence="15" type="primary">glmU</name>
        <name evidence="17" type="ORF">S2091_0758</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>H(+) + N-acetyl-alpha-D-glucosamine 1-phosphate + UTP = diphosphate + UDP-N-acetyl-alpha-D-glucosamine</text>
            <dbReference type="Rhea" id="RHEA:13509"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
            <dbReference type="ChEBI" id="CHEBI:57776"/>
            <dbReference type="EC" id="2.7.7.23"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>acetyl-CoA + alpha-D-glucosamine 1-phosphate = CoA + H(+) + N-acetyl-alpha-D-glucosamine 1-phosphate</text>
            <dbReference type="Rhea" id="RHEA:13725"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:57776"/>
            <dbReference type="ChEBI" id="CHEBI:58516"/>
            <dbReference type="EC" id="2.3.1.157"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="15">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="15">Bacterial outer membrane biogenesis; LPS lipid A biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="15">Nucleotide-sugar biosynthesis; UDP-N-acetyl-alpha-D-glucosamine biosynthesis; N-acetyl-alpha-D-glucosamine 1-phosphate from alpha-D-glucosamine 6-phosphate (route II): step 2/2.</text>
    </comment>
    <comment type="pathway">
        <text evidence="15">Nucleotide-sugar biosynthesis; UDP-N-acetyl-alpha-D-glucosamine biosynthesis; UDP-N-acetyl-alpha-D-glucosamine from N-acetyl-alpha-D-glucosamine 1-phosphate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="15">Homotrimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 15">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 15">In the C-terminal section; belongs to the transferase hexapeptide repeat family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 15">In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.23" evidence="15"/>
    <dbReference type="EC" id="2.3.1.157" evidence="15"/>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94755">
        <property type="protein sequence ID" value="PRC94755"/>
        <property type="gene ID" value="S2091_0758"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00113">
        <property type="reaction ID" value="UER00532"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00973"/>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019134">
        <property type="term" value="F:glucosamine-1-phosphate N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003977">
        <property type="term" value="F:UDP-N-acetylglucosamine diphosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000902">
        <property type="term" value="P:cell morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009245">
        <property type="term" value="P:lipid A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006048">
        <property type="term" value="P:UDP-N-acetylglucosamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd03353">
        <property type="entry name" value="LbH_GlmU_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01631">
        <property type="entry name" value="GlmU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005882">
        <property type="entry name" value="Bifunctional_GlmU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038009">
        <property type="entry name" value="GlmU_C_LbH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025877">
        <property type="entry name" value="MobA-like_NTP_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14602">
        <property type="entry name" value="Hexapep_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12804">
        <property type="entry name" value="NTP_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01173">
        <property type="entry name" value="glmU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13 15" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="10 15" id="KW-0133">Cell shape</keyword>
    <keyword evidence="14 15" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="4 15" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 15" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12 15" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="6 15" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="11 15" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 15" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 15 17" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NTP_transf_3" evidence="16">
        <location>
            <begin position="5"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Pyrophosphorylase" evidence="15">
        <location>
            <begin position="1"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="region of interest" description="UDP-GlcNAc binding" evidence="15">
        <location>
            <begin position="7"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="region of interest" description="UDP-GlcNAc binding" evidence="15">
        <location>
            <begin position="77"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Linker" evidence="15">
        <location>
            <begin position="226"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="N-acetyltransferase" evidence="15">
        <location>
            <begin position="247"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="region of interest" description="Acetyl-CoA binding" evidence="15">
        <location>
            <begin position="382"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="15">
        <location>
            <position position="359"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="21"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="72"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="101"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="136"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="150"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="165"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="223"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="329"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="347"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="362"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="373"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="376"/>
        </location>
        <ligand>
            <name>acetyl-CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="401"/>
        </location>
        <ligand>
            <name>acetyl-CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="419"/>
        </location>
        <ligand>
            <name>acetyl-CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="436"/>
        </location>
        <ligand>
            <name>acetyl-CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF12804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="PRC94755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="453" mass="48012" checksum="1718574AE9D5A214" modified="2018-07-18" version="1">MINIVILAAGMGKRMRSDLPKVLHNIAGKPLVNHVLDTARGLSPATLCVIYGHGGEQVPTKLAASDVQFAKQEPQLGTGHAVQQALPFLNETLPTLILAGDVPLTKLSSLQALVAAAGSDKLGILTVDLTDPTGYGRIVREDGKISKIVEHKDATSAQHAIREVNTGIMIMPTTKLKQWLATLSNNNAQGEYYLTDVIAKAVADGVELVSAQPDAEWETMGVNSKTQLAELERLYQRNQADLLLENGVTLLDPQRIDIRGTLQCGRDVSIDVGCIFEGNVTVEDGVQIGAYCVIKDAHLAKNSNIKPFCHIDGSTVGAGSQIGPYARLRPGAELAADVHIGNFVEVKKSQIGAHSKANHLAYIGDATIGERVNIGAGTITCNYDGVNKFRTIIEDDAFIGSDSQLIAPVTVGKGATLGAGTSLSKDAPAGQLTVSRARQVSIAGWVRPVKKTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H451</accession>
    <name>A0A2S9H451_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_0762</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94759">
        <property type="protein sequence ID" value="PRC94759"/>
        <property type="gene ID" value="S2091_0762"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12710">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003788">
        <property type="entry name" value="NDUFAF7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038375">
        <property type="entry name" value="NDUFAF7_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12049">
        <property type="entry name" value="PTHR12049"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02636">
        <property type="entry name" value="Methyltransf_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC94759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="383" mass="41842" checksum="9492DF9C65591457" modified="2018-07-18" version="1">MQKLQLPQPSPEAQAASQALLELIAQEISANGGWISFARYMELALYAPQLGYYTGGAAKLGSAGDFTTAPEISSLFGAALANFALQVLPQTANQIMEFGAGTGKLAFDLLTELHHQASPPERYYIVELSGELRSRQEQLLKDFPEVVWLQQMPASFSGLILGNEVLDAMPVQLVKKTASGWNELGVSWQAGALKWTEQALVESALLAQIPDEEALPVGYLTELHPIAQGFMTSVAQMLKAGGAGISLFIDYGFPAAEYYLHQRDQGTLMCHYRHHSHTEPFYWPGLQDITSHVDFSAMQHAGQLAGLELLCYTSQAGFLLHAGIGDVLLRTSPSDAMRYLPQANALQKLISPAEMGELFKVLAMGVNVTLPEKILQQDRSHRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H474</accession>
    <name>A0A2S9H474_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0736</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94733">
        <property type="protein sequence ID" value="PRC94733"/>
        <property type="gene ID" value="S2091_0736"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="75" mass="8329" checksum="AA56511C3004020C" modified="2018-07-18" version="1">MTQLLYSGYPNRYTAVAGDILPNISNGPPRHDGQTIIGDDYVMPGKWTGNVKIRRDKIAACPPDQILTIDVWDQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H492</accession>
    <name>A0A2S9H492_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Sodium/hydrogen exchanger family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_0800</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94797">
        <property type="protein sequence ID" value="PRC94797"/>
        <property type="gene ID" value="S2091_0800"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015299">
        <property type="term" value="F:solute:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006813">
        <property type="term" value="P:potassium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006153">
        <property type="entry name" value="Cation/H_exchanger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006037">
        <property type="entry name" value="RCK_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036721">
        <property type="entry name" value="RCK_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003148">
        <property type="entry name" value="RCK_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00999">
        <property type="entry name" value="Na_H_Exchanger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02254">
        <property type="entry name" value="TrkA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116726">
        <property type="entry name" value="SSF116726"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51202">
        <property type="entry name" value="RCK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51201">
        <property type="entry name" value="RCK_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0406">Ion transport</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0630">Potassium</keyword>
    <keyword evidence="1" id="KW-0633">Potassium transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="30"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="54"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="85"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="117"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="154"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="183"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="217"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="275"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="300"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="330"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="361"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="domain" description="RCK N-terminal" evidence="7">
        <location>
            <begin position="416"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="domain" description="RCK C-terminal" evidence="8">
        <location>
            <begin position="578"/>
            <end position="661"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC94797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="661" mass="72096" checksum="3F0657E4ED755E72" modified="2018-07-18" version="1">MQSALEITLLFLGASVFGVVIFRKLRLPPMLGYLMVGVVIGPYGFAWAENSVATQGFASFGVVFLMFSIGLEFSLPKLKSMRRTVFGLGLAQVLVTIISTMLAAWLSSLILPTIWHISWQAAFALGGAFSMSSTAIVSKILVERLEIETIHGRQIFGILLFQDLALVPLLIIAPALAAQDEHLLQTLIYAIAKATLVLVLLLFFGKKIMRGWFKLVVLLRSQELFMLNLLLITLGAAWITERAGLSLALGAFVAGMLISETEYKHQVEEDIKSFRDVLLGLFFVTIGMLLNVGLVVEHWWLVLLLLVIPVAFKCGLVVLLAKLFGGSTGVALRTGLALAQAGEFGFVLLSQMSHLNLMNPLFTQLVLASMVLSMLVAPFLLLHSDAIAMKFSHSDWMQQSLALTKIASRAMGQDKHVLIAGFGRTGQSLAILLNEEKIPYHALDLDPDRVQAAQAAGSIVSYGDAARRESLIAAGIMRASVLVVTHTGTASALKVLHYVKELNPALPVIVRSYDDSDLEKLREAGATEVVPDVIEGSLMLASHALVLLGVPVRRVVHRVQRARDDRYESLRGYFHGASDAVDDADNLQVRLQPIQLSEGAAAIGKLIAELCLAELEVEIISMRRAMQRFEFTPETRLASGDVLVLRGTTEVLALTEERLLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4B1</accession>
    <name>A0A2S9H4B1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Tfp pilus assembly protein PilO</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0784</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94781">
        <property type="protein sequence ID" value="PRC94781"/>
        <property type="gene ID" value="S2091_0784"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043683">
        <property type="term" value="P:type IV pilus assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043107">
        <property type="term" value="P:type IV pilus-dependent motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007445">
        <property type="entry name" value="PilO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014717">
        <property type="entry name" value="Transl_elong_EF1B/ribosomal_S6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04350">
        <property type="entry name" value="PilO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016482">
        <property type="entry name" value="PilO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="28"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="215" mass="23604" checksum="1A90C3E8C34A24D2" modified="2018-07-18" version="1">MKSMTELSESLSAQFRDLNGIHPGLWPIAPRLLCAIGTMIVVLGGGWYFYWSGQFDELNRGQQEEVTLKEGYKSKIQQSINLEGLRKQKVQVGLFVSALEKQLPSKAEMDALLSDITQAGLGRGLQIEMFKPGQAVPKDYYAELPIDVKASGSFHDMGAFASDVAHLSRIVTLNNLNVNTGKDGVLTLDVVAKTFRYLDPEEVASQKKAAKGAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4J6</accession>
    <name>A0A2S9H4J6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="8">KpsF: sugar isomerase, KpsF/GutQ family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_0799</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the SIS family. GutQ/KpsF subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94796">
        <property type="protein sequence ID" value="PRC94796"/>
        <property type="gene ID" value="S2091_0799"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097367">
        <property type="term" value="F:carbohydrate derivative binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901135">
        <property type="term" value="P:carbohydrate derivative metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05014">
        <property type="entry name" value="SIS_Kpsf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004800">
        <property type="entry name" value="KdsD/KpsF-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001347">
        <property type="entry name" value="SIS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046348">
        <property type="entry name" value="SIS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035474">
        <property type="entry name" value="SIS_Kpsf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01380">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004692">
        <property type="entry name" value="KdsD_KpsF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53697">
        <property type="entry name" value="SSF53697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00393">
        <property type="entry name" value="kpsF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51464">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0129">CBS domain</keyword>
    <keyword evidence="8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="SIS" evidence="7">
        <location>
            <begin position="55"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="6">
        <location>
            <begin position="224"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="6">
        <location>
            <begin position="291"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="96"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="site" description="Catalytically relevant" evidence="4">
        <location>
            <position position="73"/>
        </location>
    </feature>
    <feature type="site" description="Catalytically relevant" evidence="4">
        <location>
            <position position="125"/>
        </location>
    </feature>
    <feature type="site" description="Catalytically relevant" evidence="4">
        <location>
            <position position="166"/>
        </location>
    </feature>
    <feature type="site" description="Catalytically relevant" evidence="4">
        <location>
            <position position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR004692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR004692-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR004692-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC94796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="343" mass="36469" checksum="748619B8EDB75FAD" modified="2018-07-18" version="1">MSVPYTKSPQTTFDPIRALQLASSTLTIEADAIQALNRRLTTKSDDNLGSNFTAAVGLLLNCQGRVVVSGIGKSGHIARKIAATFASTGTPAFFVHAAEAAHGDLGMVTANDVFIAISYSGEAGELLAIMPLIKRMGAQLIAITGNPASRLAQLADVHLNAHVDKEACPLNLAPTASTTVTLALGDALAVAVLDASGFREEDFARSHPGGALGRRLLTHVRDVMRTGKDIPSVQLDCSLIAALLEITKKGIAMTAVVDANNHLLGVFTDGDLRRLLERMHDFTDIKIADVMHKNPRTIGPDKLAVEAVKLMETHRINQLLVADHEGKLVGALHIHDLTRAKVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4N0</accession>
    <name>A0A2S9H4N0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0139</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94944">
        <property type="protein sequence ID" value="PRC94944"/>
        <property type="gene ID" value="S2091_0139"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002123">
        <property type="entry name" value="Plipid/glycerol_acylTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01553">
        <property type="entry name" value="Acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00563">
        <property type="entry name" value="PlsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PlsC" evidence="1">
        <location>
            <begin position="41"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="207" mass="23572" checksum="2F798478FAB409A1" modified="2018-07-18" version="1">MHHTIFDTPVVNTVMRWISVLMLRLLGWRVDGKAPDEAKYVLIAAPHTSNWDFPFTLMVCFALRLRVYWMGKSSLFPPVMGSVMRWLGGIPVDREKSGNLVQGTIDAFNRTERLTVIVPPEGTRDKVSHWKTGFYYIALGAKVPILLGFMDFKDKVGGVAHLFHPSGDIEHDMQEIKQFYRGFTGKNPQQFDDETIQIKAGSKDRES</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4P8</accession>
    <name>A0A2S9H4P8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="10">FtsX-like permease family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">S2091_0147</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94952">
        <property type="protein sequence ID" value="PRC94952"/>
        <property type="gene ID" value="S2091_0147"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025857">
        <property type="entry name" value="MacB_PCD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12704">
        <property type="entry name" value="MacB_PCD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="21"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="291"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="343"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="386"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="430"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="682"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="734"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="768"/>
            <end position="787"/>
        </location>
    </feature>
    <feature type="domain" description="MacB_PCD" evidence="9">
        <location>
            <begin position="20"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="8">
        <location>
            <begin position="323"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="domain" description="MacB_PCD" evidence="9">
        <location>
            <begin position="459"/>
            <end position="648"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF12704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC94952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="804" mass="87537" checksum="CFB1DEBD5D5A1DE5" modified="2018-07-18" version="1">MNLRDFRIGWRLLINEPAYSMVVIFGLTLGFAVCFLLLGFVRYSFSYDSQVPDNENVYVLQHKVNIMPVPQWMEFMPMPVRSVALNSGMVSSVSAAIPISVTIKVGNHMVKDELMAVDPSFQTMWGVMPLEGDLHAALTRPDAIALTVSLAQKIFGEMHVLGKTLDIKGKQFQVVALLPEAQLNTTLPYTALVGLNTQAMTDEGRSGMLSQWQRVTGKVYLKLAAGITPAQMTEILQNAFDHSPWTEFPPEMLKRLGHNKIFDVRLVSLQNAYFDMDVANNLRSGPRASKLGVLALAGVALLILILASTNFVNLATVRTLRRKREIAVRKILGAKAGRVVSQFFAEAILVSLTATCLGLLLAWLLLPLFSDLVNRHLGNLFTPAYCLISLSIGVLIGLVSGLYPTWVALKVHPALVLSGRSNSNSIGSLLIQRGLTALQFSIAMMLSAIAVAIAWQTSFATHRDPGFDTSNLITITMPDDAGHENIVSFREQLLHLPDVQGVTATEKAVGEQGIGSSTDYKSADGKSVSAVVAYVGANFFDVYGLKPVFGRLFNSAIEFDENAGVVVINSVAARAFGFATPEAAIGQIIQGTFAGMKPLKIIGIAPDIRHQNLREVIQPLVYLPNNEDLLTLTVRTSGDVSRLESAIENIWQKKFPPYALQMRRVKNVFIEIYAEDLGLAKMIGIASLVAIGLALFGVYALSANNLQRRHREIILRKLYGATSQKIAKLVARDFIGLVALGAIVGLPIAGVVIARYMSSFVERAPLGIWPLVAAFGLALIIALIATLRHTLIAIRMKPAQALSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H587</accession>
    <name>A0A2S9H587_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Outer membrane lipoprotein carrier protein LolA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0345</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95150">
        <property type="protein sequence ID" value="PRC95150"/>
        <property type="gene ID" value="S2091_0345"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16325">
        <property type="entry name" value="LolA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029046">
        <property type="entry name" value="LolA/LolB/LppX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004564">
        <property type="entry name" value="OM_lipoprot_carrier_LolA-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19574">
        <property type="entry name" value="LolA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89392">
        <property type="entry name" value="SSF89392"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015734553" evidence="2">
        <location>
            <begin position="22"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC95150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="204" mass="21921" checksum="2167FE2CC5B1154B" modified="2018-07-18" version="1">MLKQLCTLFCWAALASNASVAAPSPVVTKIQSMLAKPSVLCGRFDQTKQLNGMKKPLASNGRFCVVAGKGVVWRTLQPFPNTLRLTRDEIVNYQGDRVAMRLDAKQEPTVRMINSVLFSLLAGDLAQLDTLFEVDGNADAATWHVALKAREPALAKAIGAISLDGGAYVKTININEASGDHTTIVFSAIQTGDTAMQPEEAALF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5C4</accession>
    <name>A0A2S9H5C4_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Aldehyde dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_0362</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3 7">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95167">
        <property type="protein sequence ID" value="PRC95167"/>
        <property type="gene ID" value="S2091_0362"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016620">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006081">
        <property type="term" value="P:cellular aldehyde metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012394">
        <property type="entry name" value="Aldehyde_DH_NAD(P)"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43570">
        <property type="entry name" value="PTHR43570"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036492">
        <property type="entry name" value="ALDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
        <property type="entry name" value="ALDEHYDE_DEHYDR_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldedh" evidence="8">
        <location>
            <begin position="68"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="active site" evidence="4 5">
        <location>
            <position position="256"/>
        </location>
    </feature>
    <feature type="active site" evidence="4 6">
        <location>
            <position position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR036492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR036492-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC95167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="513" mass="57510" checksum="F95C39BD99EA788D" modified="2018-07-18" version="1">MRFEQVCLGVLLQNTNRPMFYVICVSPTLIESSRTMNARLNSEIPTEFSDCFQKQRAAYLKDPVPSYDSRRSDLQQLARMLNENKDEIIAAINADYGNRSTFETLFAEFFVVLQEIKDNMKHLKKWMRPQRRKIDFMLYPTSRAAVIPQPLGVVGVIVPWNFPLNLSFAPLAAIFAAGNRAMLKMSENSNNLARLLIKIAPLYFSADKLQFFEDGGGRGPAFSSIPFDHLFFTGSGQTGRAVMANAARNLTPVTLELGGKSPAVVGVDFPIASAVGQILWAKAFNAGQICTNIDYVFIPEGSEAAFITEAQQIIAKRYPDINHNDYTSIIDQRSYHRLQETLNEAIKKGARSVNLFEGSNPDPAMRKFPLTLVFDVSDNMQIMQREIFGPLLPIKTYRNAQEVVDYINAHDRPLALYPFTNDKQLQDFYITHVMSGGVSVNTALLHVAQHDIPFGGVGASGMGHYHGHEGFVTFSKLRPIYYQGFFSAIKLLMMPPYNNGANTFIKLLIKLFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5K2</accession>
    <name>A0A2S9H5K2_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 10">Adenine phosphoribosyltransferase</fullName>
            <shortName evidence="10">APRT</shortName>
            <ecNumber evidence="5 10">2.4.2.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">apt</name>
        <name evidence="12" type="ORF">S2091_0459</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>AMP + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + adenine</text>
            <dbReference type="Rhea" id="RHEA:16609"/>
            <dbReference type="ChEBI" id="CHEBI:16708"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.4.2.7"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 10">Purine metabolism; AMP biosynthesis via salvage pathway; AMP from adenine: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the purine/pyrimidine phosphoribosyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.7" evidence="5 10"/>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95264">
        <property type="protein sequence ID" value="PRC95264"/>
        <property type="gene ID" value="S2091_0459"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00588">
        <property type="reaction ID" value="UER00646"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003999">
        <property type="term" value="F:adenine phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006168">
        <property type="term" value="P:adenine salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044209">
        <property type="term" value="P:AMP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006166">
        <property type="term" value="P:purine ribonucleoside salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00004">
        <property type="entry name" value="Aden_phosphoribosyltr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005764">
        <property type="entry name" value="Ade_phspho_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRibTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00156">
        <property type="entry name" value="Pribosyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01090">
        <property type="entry name" value="apt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 10 12" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9 10" id="KW-0660">Purine salvage</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 10 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pribosyltran" evidence="11">
        <location>
            <begin position="31"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PRC95264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="180" mass="19871" checksum="B85D77707E8C020F" modified="2018-07-18" version="1">MYNPSDYIKNHIRTVANWPQDGVMFRDITPLLQNPKTFRVLIDLFVHRYMDANLDLIAGMDARGFIIGSVVAYELNLGFVPIRKKGKLPFTTMSEEYTLEYGSATVEMHTDACKPGDRVVLIDDLIATGGTMLAGKKLLERNGAFIIEGAAIVDLVDLGGSAMLKKSGLPLFTVCEFDGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5L2</accession>
    <name>A0A2S9H5L2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_0470</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95275">
        <property type="protein sequence ID" value="PRC95275"/>
        <property type="gene ID" value="S2091_0470"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007452">
        <property type="entry name" value="TamB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04357">
        <property type="entry name" value="TamB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="29"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC95275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="1387" mass="148542" checksum="CC56784F05BD4A33" modified="2018-07-18" version="1">MTDPTNTANHINAAAATPKQNKKSVARRIFNMLFLSALLFIALLILAAAWLVATEAGAKTTLALLDRYASIHSQGVSGSLLHQLKIQHIELRNKELDLVVDDVALQWQPSALWRQQLQLDYLRINSLQLALAPTPSDDKPAILPASLSLPRLIKLVKADQLAINNFQLSTLDASGKHGGVQQFSALTAQVVINSENYQLQFSGTTPWGNAALSGNLGSAAPFNLQAKFDWQGLAIQQSGVTVPVTQLHGTLSGNLKKLLLQAQLDVAEIEKNAAPNFKPASGQIHAVLTPFSVLPLDTLQLDLNSVNPASFYADAPKANLHLKADFKAVGDVKAPILRGHFAIKNTMPMIWNAGGIPVAAISSDITLDEHQISWQATQIELEAGGSVLGSGHLNLHKTALPDLFAQLDLKNVDLLHIDKRLKKTQLSGQVRVENITTGLQFALNLHESQPNLSANLKANVHLSNEQLLSVQKLELLAKDATLNAQGSFALQGRQEFLLQGEAHNLNPARWIDVPEGHIATRFKVAGQVQQGWRIDAQLAELSGQFAGLALQGESNLIAQQGKLLSIKKLELNWGKSHLSASGNWQLNESANANQHEQLQLALAVPDLAALSRPFEKIVPISLKGSLFVDGILSGNSKQPSGRLNVKADKLAIPELITLEKLQANIELAEGITGKIDGNLELTGLAAGKSETENFKIERIQASLSGLRHAHQLHVSANLPQQHQIELQAQGDLQEASAGTDNVTQWQGQIQKLNLAGELDFQLAAPFALKISSKAAQMGAANWQGKLGQLQVQQVNWSRGQLSTQGKLQGLQVVNALKLWHADIPLAGKLQIDAAWQLDIGQQIAGQFEIKRTSGDLSVKDMASGYNQTLALGLQNLFLKASTGDGGGSARQQAINVQLQAQGAQLGQIEANLRSAVNKTEQGWALAANAPLSGTASIQIQNIQWVSQLLGSGIALRGELQAQGQLSGTLDKPDYSAQINGKDLQISLTELGVLLPNGSLKASMDKTQFTLSSLKFSQTIKAPPRHDKLTEFTWLNETGFVESSGTVDLQSGRGSITTRWQHFPFLQNADSWLVATGDAQLTESGKTWNLTGQLLADGAYFSVPKQAPPKLSSDVVVLKKNAKKSVEKSDGLQSSVDFSIKTGKNFVFVGRGLDTSLDGDLRIRIKNGGSILATGSIQTTGGTYEGYGQQLAIERGILNFQGAPDNPGLNVRAIRRGLPVEAGVEVIGTVAKPEVRLISEPNVPDPDKLSWMVLGRSSDQMAGSEAALLMSAAGAIFGGDSGSGSNMPRDIAHSLGLDDLSVGTTSTAPGSQLPSQTVAGNISATSPNEQAFSVGKRITPNLVFSIERSLTDATNGLKLTWQLTRRFSVIGRAGSDTAIDGQYTFSFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GS69</accession>
    <name>A0A2S9GS69_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4742</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000064">
        <property type="protein sequence ID" value="PRC90551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90551">
        <property type="protein sequence ID" value="PRC90551"/>
        <property type="gene ID" value="S2091_4742"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014449">
        <property type="entry name" value="UCP007050_HI0931"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10008">
        <property type="entry name" value="DUF2251"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC90551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="139" mass="15704" checksum="7969AD09430C270A" modified="2018-07-18" version="1">MTKLRSIQFVTEEKFKFGNETVVEGDAPQGSFTVFFEDDGSTGYFYAVDTVLKEQIIQDALHIYSIGGDMERGKDCVAKIGWSTDSQKALLLIDDRVHAVFDFDERQGYCLTGYPAAPSNNVWSTRGHEWNDEALEKFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSI9</accession>
    <name>A0A2S9GSI9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">YD repeat (Two copies)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_4641</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000040">
        <property type="protein sequence ID" value="PRC90658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90658">
        <property type="protein sequence ID" value="PRC90658"/>
        <property type="gene ID" value="S2091_4641"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031325">
        <property type="entry name" value="RHS_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006530">
        <property type="entry name" value="YD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05593">
        <property type="entry name" value="RHS_repeat"/>
        <property type="match status" value="13"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01643">
        <property type="entry name" value="YD_repeat_2x"/>
        <property type="match status" value="19"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51782">
        <property type="entry name" value="LYSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LysM" evidence="2">
        <location>
            <begin position="4990"/>
            <end position="5037"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="3674"/>
            <end position="3703"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC90658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="5961" mass="621999" checksum="CD3A4EBF076CAF73" modified="2018-07-18" version="1">[encoded data, 5961 characters]</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSM1</accession>
    <name>A0A2S9GSM1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Efflux transporter, RND family, MFP subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_4545</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000037">
        <property type="protein sequence ID" value="PRC90719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90719">
        <property type="protein sequence ID" value="PRC90719"/>
        <property type="gene ID" value="S2091_4545"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006143">
        <property type="entry name" value="RND_pump_MFP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01730">
        <property type="entry name" value="RND_mfp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="domain" description="HlyD_D23" evidence="5">
        <location>
            <begin position="75"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="393"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="120"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC90719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="419" mass="44513" checksum="E17DA0F53D40FB31" modified="2018-07-18" version="1">MNSNNKLTSSTKPLYAAMVVTGIVGVAVLVLAGCNFATGKTNESQAASPAGGPPVSVSAVIEKQIEQTQEFSGRLEAIERVDIRSRVSGFITEVNFKPGSEVKKGAVLFVIDPRPYQAELDRAEAAASSARAKAELAKLELNRSEKLLAEKAIAQREYDESASSMKELDANARAAQASYEAAKLNLSYTQVKSPIDGRVSKAEITTGNLIDASAILTSVVSTDHIYASFDGDEDTYLRVGALSHQGKAVAVRVGLANETGFPHEGKLEFVDNQLDPQTGSVRMRATFINADNVLVPGLFARVQLGGGKDLTKALLINDRAVGTDQNRKFVFVIDANNKAEYRPVKLGQTVAGLRVVSEGLKAGENVVVNGLQRVHPGAPITPEVVTMDFDPAATPDKTAKAPKVAMNATTAKNTTSTKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSP4</accession>
    <name>A0A2S9GSP4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Pirin-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_4563</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the pirin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000037">
        <property type="protein sequence ID" value="PRC90737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90737">
        <property type="protein sequence ID" value="PRC90737"/>
        <property type="gene ID" value="S2091_4563"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012093">
        <property type="entry name" value="Pirin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003829">
        <property type="entry name" value="Pirin_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041602">
        <property type="entry name" value="Quercetinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43212">
        <property type="entry name" value="PTHR43212"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02678">
        <property type="entry name" value="Pirin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17954">
        <property type="entry name" value="Pirin_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006232">
        <property type="entry name" value="Pirin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pirin" evidence="3">
        <location>
            <begin position="6"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="Pirin_C_2" evidence="4">
        <location>
            <begin position="144"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003457"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF17954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC90737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="231" mass="25241" checksum="03BEBFD1F547A97E" modified="2018-07-18" version="1">MITLRHTQERGQADHGWLKSQHSFSFAGYYDPEHMGWGNLRVINEDRLAAGAGFGTHGHQDMEIISYVLSGALAHQDDMGNGTTIPAGDVQRMSAGSGVRHSEFNKLDDQATHFFQIWILPNVQGIKPGYEQKTFDVQAGSMQLIASPDGDNGSVTIHADALLYRGFFNDADQVSLALSPKRKAYLHLVRGEIRVNDLTLQAGDAVLVANESMLNLSGAENAEVLFFDLAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSP7</accession>
    <name>A0A2S9GSP7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">AhpC/TSA family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4559</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000037">
        <property type="protein sequence ID" value="PRC90733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90733">
        <property type="protein sequence ID" value="PRC90733"/>
        <property type="gene ID" value="S2091_4559"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016209">
        <property type="term" value="F:antioxidant activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000866">
        <property type="entry name" value="AhpC/TSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
        <property type="entry name" value="AhpC-TSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="1">
        <location>
            <begin position="3"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="172" mass="19441" checksum="1B6C51346637F0EE" modified="2018-07-18" version="1">MKVRIGQKINSFTVETINGEQQMVPDPSRKFTHLQFRRFAGCPICNYHLHTFTKSAEQLKAADIQEIILFHSSATEMRKFQHDIPFATVADPEKTLYKKFGVDKSLFATMHPKPLWAGIRGMVLGKVGLKVENGPLGLPADILINQEGIVVAFKYGTHAYDQWEVNELLKIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSU1</accession>
    <name>A0A2S9GSU1_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 12">Flagellar biosynthetic protein FliP</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">fliP</name>
        <name evidence="14" type="ORF">S2091_4535</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Plays a role in the flagellum-specific transport system.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Cell membrane</location>
            <topology evidence="12">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="12">Bacterial flagellum basal body</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the FliP/MopC/SpaP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000036">
        <property type="protein sequence ID" value="PRC90787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90787">
        <property type="protein sequence ID" value="PRC90787"/>
        <property type="gene ID" value="S2091_4535"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009425">
        <property type="term" value="C:bacterial-type flagellum basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044781">
        <property type="term" value="P:bacterial-type flagellum organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005837">
        <property type="entry name" value="FliP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005838">
        <property type="entry name" value="T3SS_IM_P"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30587">
        <property type="entry name" value="PTHR30587"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30587:SF0">
        <property type="entry name" value="PTHR30587:SF0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00813">
        <property type="entry name" value="FliP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00951">
        <property type="entry name" value="FLGBIOSNFLIP"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01302">
        <property type="entry name" value="TYPE3IMPPROT"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01103">
        <property type="entry name" value="fliP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01061">
        <property type="entry name" value="FLIP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0975">Bacterial flagellum</keyword>
    <keyword evidence="7 12" id="KW-1005">Bacterial flagellum biogenesis</keyword>
    <keyword evidence="11 12" id="KW-1006">Bacterial flagellum protein export</keyword>
    <keyword evidence="5 12" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="14" id="KW-0966">Cell projection</keyword>
    <keyword evidence="14" id="KW-0969">Cilium</keyword>
    <keyword evidence="14" id="KW-0282">Flagellum</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-0653">Protein transport</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0732">Signal</keyword>
    <keyword evidence="6 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 12" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015736609" description="Flagellar biosynthetic protein FliP" evidence="13">
        <location>
            <begin position="34"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="57"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="98"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="197"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="231"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006257"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU362069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="PRC90787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="256" mass="28041" checksum="41F09F24E2090FEB" modified="2018-07-18" version="1">MSKKPKPNNHLASTALISISLCLLCLISNDAFAQVPVVTSTPTTGGGQNYVLSIQTLLFLTSLSFLPAALLMMTSFTRIVIVLSMLRQAIGTASSPPNQVIIGLSLFLTLFVMSPVIDKIYQDAYQPFNENKITLTDALDKGAKPLKQFMMKQTRQADLALYIKLARSPQIQGPEDVTLTVLIPAFITSELKTAFQISFAIFIPFLIIDMVVACVLMSMGMMMMSPATVSLPFKIMLFVLVDGWQLLIGSLAQSFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GT11</accession>
    <name>A0A2S9GT11_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="12">ABC-type bacteriocin/lantibiotic exporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">S2091_4422</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000034">
        <property type="protein sequence ID" value="PRC90841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90841">
        <property type="protein sequence ID" value="PRC90841"/>
        <property type="gene ID" value="S2091_4422"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="PTHR24221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="SSF90123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-1278">Translocase</keyword>
    <keyword evidence="2 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="198"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="232"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="305"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="336"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="431"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="11">
        <location>
            <begin position="198"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="511"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="545"/>
            <end position="552"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PRC90841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="739" mass="82004" checksum="C4308805ADD9A74B" modified="2018-07-18" version="1">MPRRLLRLVSTPWQDNSRPSAAPYVFSVDDVVWAMGSFCALNRKPFDAGLLTKQFPPPYNADSFIHAGRALGFKIKRKECKEGTSQEVGRLNLPCLVVMEVQQAIIDVVDQVASRTTRPALVVQVTEEHVILFEAGSNVPKTLTPEEFESAFTGTAFQLALATLALKDPDGAQGQHTTFGFKWFIPELLKHRKVWRDVLIASLIIQLLALGTPLFTQVVIDKVVVHRTESTLIVIAIGLGVFMLFSALLSWVRQYLVLHTGNRVDAVLGSAVFNHLFKLPPRYFEHRPTGVIAARLHGVETIREFVASAAVTLTLDFPFLLIFVGIMFYYSVMLSLVALSLISCIVLLSLIMAPIFRTRLNQQFLLSARNQAFITEYVSGLETVKSLQMEPQLSARYGDYLADYLQAGFSMKQIANTYNVVANGLEQLMSLLILVVGAYTVMHDSTFTIGMLIAFQMFAGRVSQPMLRIVGLWQQFQQANMSVQRLGDIMNAPTEPYSILPSRLRENRGSIDIENLSFRYGDNLPYLYQGFAMKVEPGKVVAIMGPSGSGKSTLAKLLQGFYIPADGQIKLDGNDIRYLSANELRHYFGVVPQETVLFSGTIYDNLLMANPHATFDQAVHACKMAEIHDTIEGLPQGYQTEIGERGVGLSGGQKQRMAIARALLKQPKILVFDEATSSLDSETAEHFAATINQLKGKVTMLFITHALPKSLLVDEVVQIGRKASDENGIQLNQRGYQTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTA1</accession>
    <name>A0A2S9GTA1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="8">PEP-CTERM-box response regulator transcription factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_4353</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000032">
        <property type="protein sequence ID" value="PRC90952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90952">
        <property type="protein sequence ID" value="PRC90952"/>
        <property type="gene ID" value="S2091_4353"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002197">
        <property type="entry name" value="HTH_Fis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014264">
        <property type="entry name" value="Sig_transdc_resp-reg_PEP-CTERM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002078">
        <property type="entry name" value="Sigma_54_int"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025662">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025943">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02954">
        <property type="entry name" value="HTH_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00158">
        <property type="entry name" value="Sigma54_activat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01590">
        <property type="entry name" value="HTHFIS"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02915">
        <property type="entry name" value="PEP_resp_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00675">
        <property type="entry name" value="SIGMA54_INTERACT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00676">
        <property type="entry name" value="SIGMA54_INTERACT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50045">
        <property type="entry name" value="SIGMA54_INTERACT_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Response regulatory" evidence="7">
        <location>
            <begin position="7"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma-54 factor interaction" evidence="6">
        <location>
            <begin position="148"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="5">
        <location>
            <position position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC90952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="450" mass="49960" checksum="B1CCD948F3F9902A" modified="2018-07-18" version="1">MNQEKKKLLIIEDDLGLQKQLRWSLDAYEVIVAGDRESAMAQVRRHEPAVITMDLGLPPDPDGSSEGLAILQQVLSMAPDTKLIVLSGNQDRQNALKAIAMGAYDFHQKPCDPEMLNLVIQRAFFLHALQQENRRMLQNQAASPMAGVITRDPAMLKVCRNIEKVGPSSASVMLLGDSGTGKEVLARALHQLSPRQDKRFMAINCAAIPENLLESELFGYEKGAFTGAVKQNLGKIELANEGTFFLDEVGDLPMALQAKLLRFLQERVFERIGGHKEIPVDVRIVCATHQNLKELASTGRFREDLYYRLSEIVINIPPLADRAGDAALLAHHFKNKFNAKEGRPGLNFSQDALALIESHRWPGNVREMENCIKRAVIMADGLQITVEDLGLSANNIAEEPINLRQIREDAEYKAVVKALAHVDGNIAKAAELLGISRPTLYDLMNRHSIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTA9</accession>
    <name>A0A2S9GTA9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Pyridoxal-dependent decarboxylase, exosortase A system-associated</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_4355</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Orn/Lys/Arg decarboxylase class-II family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000032">
        <property type="protein sequence ID" value="PRC90954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90954">
        <property type="protein sequence ID" value="PRC90954"/>
        <property type="gene ID" value="S2091_4355"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016831">
        <property type="term" value="F:carboxy-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.37.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009006">
        <property type="entry name" value="Ala_racemase/Decarboxylase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017530">
        <property type="entry name" value="DCO2ase_PEP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022643">
        <property type="entry name" value="De-COase2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022644">
        <property type="entry name" value="De-COase2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000183">
        <property type="entry name" value="Orn/DAP/Arg_de-COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029066">
        <property type="entry name" value="PLP-binding_barrel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02784">
        <property type="entry name" value="Orn_Arg_deC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00278">
        <property type="entry name" value="Orn_DAP_Arg_deC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01179">
        <property type="entry name" value="ODADCRBXLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50621">
        <property type="entry name" value="SSF50621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51419">
        <property type="entry name" value="SSF51419"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03099">
        <property type="entry name" value="dCO2ase_PEP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Orn_DAP_Arg_deC" evidence="3">
        <location>
            <begin position="42"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="domain" description="Orn_Arg_deC_N" evidence="4">
        <location>
            <begin position="50"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC90954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="413" mass="44221" checksum="695D08338952059B" modified="2018-07-18" version="1">MSMNSDKPVHAAQTSFTVADNCLQVGNVSLTRLALRVGGTPFYAYDREVISAKIHTLRSVLPAQLALHYSIKANPMPAVVQHLAGLVDGLDVASAGEMQLALDTLTPSERISFAGPGKTDAELQQAVAAGVVLNLESVNELRRLQRISGELGYVPKIVLRVNPDFELKSSGLKMGGGAKQFGIDAELVPEVLAELANMDMEFLGFHIYAGSQNLNPEAIIEAHAKSSAMAIRLADIARQEVRTLNLGGGFGIPYFPGDIPLDIAPIADHLHRCLERVKLALPKATVALELGRYLVGEAGIYVTRVIDKKMSRGKCYLITDGGLHHHLAASGNFGQVLRKNYPVAVGDKMQTMSDELVSVVGPLCTPLDLLADQMPLAHAEVGDLIVVFQSGAYGYSASPMAFLSHPSAREVLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTI5</accession>
    <name>A0A2S9GTI5_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Y1_Tnp domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4323</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000031">
        <property type="protein sequence ID" value="PRC91027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91027">
        <property type="protein sequence ID" value="PRC91027"/>
        <property type="gene ID" value="S2091_4323"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002686">
        <property type="entry name" value="Transposase_17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036515">
        <property type="entry name" value="Transposase_17_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM01321">
        <property type="entry name" value="Y1_Tnp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143422">
        <property type="entry name" value="SSF143422"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Y1_Tnp" evidence="1">
        <location>
            <begin position="20"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="190" mass="21725" checksum="1374DEDC4A3484A9" modified="2018-07-18" version="1">MKPNLPSRQSLRLKDYDYSLPGLYFITICSDRRIPLFGQIADDQMSLNGAGEMIAKRWMELPLRYPKIELHEFIVMPNHLHGILQINPMVKIVGASLVGALGISTENSEPPVSTSAPVVTIGQIVGAFKSLTTNDYVQGVRDNGWPKFNKKIWQRNFYEHVIRNEKSYLSIAEYIQTNPQRWLDDIYCVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTJ3</accession>
    <name>A0A2S9GTJ3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NYN domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4218</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000030">
        <property type="protein sequence ID" value="PRC91030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91030">
        <property type="protein sequence ID" value="PRC91030"/>
        <property type="gene ID" value="S2091_4218"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004540">
        <property type="term" value="F:ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021139">
        <property type="entry name" value="NYN_MARF1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01936">
        <property type="entry name" value="NYN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NYN" evidence="1">
        <location>
            <begin position="108"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="220" mass="24826" checksum="637E61E6034434BB" modified="2018-07-18" version="1">MYYGRLRGTSFKWLDIVQLFQALLIQRSQNEHLEKVNFFTAPALANFATHGVASVNAQSAYHRALKKLHGDRLEITNGTHTFDSKGTLLPAFTSGQPYNRTNRVRVWKLEEKKTDVNLALSMYRDATKGLYDRIILVSNDSDAEPALQVIRQDFPHIMIGVVMPIHPPKPGSTVNRRASGSLSNHSDWAITHLTDDQLSLAQLPSMVSTNKKPILKPEHW</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTN7</accession>
    <name>A0A2S9GTN7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Response regulator receiver domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_4263</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000030">
        <property type="protein sequence ID" value="PRC91075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91075">
        <property type="protein sequence ID" value="PRC91075"/>
        <property type="gene ID" value="S2091_4263"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="20"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="97" mass="10743" checksum="C9361D11810565C0" modified="2018-07-18" version="1">MQNIILPLLSIPENQPHQSTLLYVEDNPANLLLVERLISRRSDIKLLTATNGGAGIKIARNHRPNMIILDISSVPTFLIGETSVLVDFHHQINLIAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTQ8</accession>
    <name>A0A2S9GTQ8_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">L-lactate dehydrogenase</fullName>
            <ecNumber evidence="6">1.1.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">lldD</name>
        <name evidence="10" type="ORF">S2091_4123</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>(S)-lactate + A = AH2 + pyruvate</text>
            <dbReference type="Rhea" id="RHEA:45816"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:16651"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.-.-" evidence="6"/>
    <dbReference type="EMBL" id="PUGF01000028">
        <property type="protein sequence ID" value="PRC91122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91122">
        <property type="protein sequence ID" value="PRC91122"/>
        <property type="gene ID" value="S2091_4123"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004457">
        <property type="term" value="F:lactate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019516">
        <property type="term" value="P:lactate oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02809">
        <property type="entry name" value="alpha_hydroxyacid_oxid_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01559">
        <property type="entry name" value="L_lact_dehydr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012133">
        <property type="entry name" value="Alpha-hydoxy_acid_DH_FMN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000262">
        <property type="entry name" value="FMN-dep_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037396">
        <property type="entry name" value="FMN_HAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008259">
        <property type="entry name" value="FMN_hydac_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020920">
        <property type="entry name" value="LldD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01070">
        <property type="entry name" value="FMN_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000138">
        <property type="entry name" value="Al-hdrx_acd_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00557">
        <property type="entry name" value="FMN_HYDROXY_ACID_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51349">
        <property type="entry name" value="FMN_HYDROXY_ACID_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 8" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6 8" id="KW-0288">FMN</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FMN hydroxy acid dehydrogenase" evidence="9">
        <location>
            <begin position="1"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6 7">
        <location>
            <position position="275"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6 8">
        <location>
            <position position="24"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="77"/>
            <end position="79"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 8">
        <location>
            <position position="106"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 8">
        <location>
            <position position="127"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 8">
        <location>
            <position position="129"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6 8">
        <location>
            <position position="155"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 8">
        <location>
            <position position="164"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6 8">
        <location>
            <position position="251"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="273"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="275"/>
        </location>
        <ligand>
            <name>glyoxylate</name>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 8">
        <location>
            <position position="278"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="306"/>
            <end position="330"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="306"/>
            <end position="310"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="329"/>
            <end position="330"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00024042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000138-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000138-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC91122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="379" mass="41001" checksum="3EED2731776D8622" modified="2018-07-18" version="1">MIISSAADFREAARRKLPRFLFDYIDGGSYVEHTLKANSADLANICLRQRVLKNITNLSLETELFGQKQAMPIVFGPVGLSGMFARRGEVQVAKAAANKGIPFTLSTVSVCSMEEVAAQSSQPIWFQLYVLKDRGFMKNALERAQAAGIKNLVFTVDMPIPGARYRDAHSGMSGRYSAPRRILQAMTKPAWAFDVGINGRPHDLGNVSAYLGKAITLEDYIGWLGKNFDASISWSDLEWVREFWKGPMIIKGILDPDDARDAVKFGADGIVVSNHGGRQLDGVLSTAKALPSIAQAVGSDLTVLADSGVRSGLDVVRMLALGAKGVLLGRAAAYALATNGQQGVEHLLDIFAQEMRVAMTLTGVTTIAQIDETILNLKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTU8</accession>
    <name>A0A2S9GTU8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">EAL domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_4129</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000028">
        <property type="protein sequence ID" value="PRC91128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91128">
        <property type="protein sequence ID" value="PRC91128"/>
        <property type="gene ID" value="S2091_4129"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01948">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001633">
        <property type="entry name" value="EAL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035919">
        <property type="entry name" value="EAL_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00563">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00052">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141868">
        <property type="entry name" value="SSF141868"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50883">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="8"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="domain" description="EAL" evidence="3">
        <location>
            <begin position="145"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC91128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="415" mass="45747" checksum="B4ADA8378ECDE62E" modified="2018-07-18" version="1">MNNWTNKSVLIVEDSSVQRTHLAGLFKSLNFGTVLEACNGVDALRVLSTHGIGMVDLVITDLDMPHMDGIELINHLSDRQLTKHLIVTSARDPRMLEVVESMGLDDAGMHLLGTVVKPVKITDLLTTLQRADHIISHSPAILDPSRFDLAELETALEQGQFIAFFQPKIEVATGIIKGVEALARWRHPEHGILSPLHFIPRIEGSPLMEPFTLAIVGQSLRELVNWHHAGLTSIKVSINLSAENLANLGFIERLVSITNAYGVEPESVIWEVTETMVMSNLSQCLANLVRLRLKGFGLAMDDYGIGYSSMQQLSRCPFTELKIDRAFVDGASERPNRLVILESSIDMGHRLGVVTVAEGVEALADWGLLQELGCDIAQGYLIAKPMQASELLDWIDTNRVRLQSLAKRASVKNSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTW7</accession>
    <name>A0A2S9GTW7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative glycerate kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_4202</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000029">
        <property type="protein sequence ID" value="PRC91106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91106">
        <property type="protein sequence ID" value="PRC91106"/>
        <property type="gene ID" value="S2091_4202"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008887">
        <property type="term" value="F:glycerate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1480.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037035">
        <property type="entry name" value="GK-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038614">
        <property type="entry name" value="GK_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007835">
        <property type="entry name" value="MOFRL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025286">
        <property type="entry name" value="MOFRL_assoc_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039760">
        <property type="entry name" value="MOFRL_protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12227">
        <property type="entry name" value="PTHR12227"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13660">
        <property type="entry name" value="DUF4147"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05161">
        <property type="entry name" value="MOFRL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DUF4147" evidence="2">
        <location>
            <begin position="10"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="domain" description="MOFRL" evidence="1">
        <location>
            <begin position="314"/>
            <end position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="426" mass="44206" checksum="79999500BEA9C4A3" modified="2018-07-18" version="1">MNSFVPKTFLLELFNCAVNAVSAEKCLPSYLPTPPVHGKTIVIGAGKGAAAMARVIEQHWPGEISGLVVTRYGHGADCQKIEVVEAAHPVPDEAGRQAAARMLNMVHGLTEHDLVLCLISGGGSALLSLPAEGITLEQKQAINKALLKSGATIAEINCVRKHLSAIKGGRLALACAPARVVTLLISDIPGDDATIIASGPTLPDATTCAEALAILRHYGITIPANIEQHLASSAGETPKPGDTRFANNSHQIIASAQTALTAAADLARAAGITPYILSDKMEGEAREVGNMHAVLAKQIARQVNLQGQPFKKPCVLISGGETTVTVRGSGRGGRNAEFLLSLAIGLDGQPDIYAIACDTDGIDGSEDNAGAVLSPDSIARATSLAIEAQALLDNNDGYGFFSALGDLVISGPTRTNVNDFRAVLIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GU05</accession>
    <name>A0A2S9GU05_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Dipeptidyl aminopeptidase/acylaminoacyl-peptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_4088</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S9C family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000027">
        <property type="protein sequence ID" value="PRC91193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91193">
        <property type="protein sequence ID" value="PRC91193"/>
        <property type="gene ID" value="S2091_4088"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011659">
        <property type="entry name" value="PD40"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07676">
        <property type="entry name" value="PD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015624532" evidence="3">
        <location>
            <begin position="24"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S9" evidence="4">
        <location>
            <begin position="478"/>
            <end position="687"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC91193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="688" mass="76239" checksum="E470FF2DB62EEFB7" modified="2018-07-18" version="1">MKLRLLLITALCAAQFTTTHALAAPRGFTVEDMVKMERVGSPLMSPDASKVIYTVRSTDSAKNAGHTEIWMLDLRDAHAMPHRLTHAAASSSDPEWSPNGDAVYFLSARSGTSQVWRLPMNGGEAEMATDLPLDVTSFRLSPRADRIALSVEVFRDCADLACTKKRLDEQTKTQASGHVFDKLFVRHWDTWADGRNTVLYSTALDATGHARGELANLSGSLDGDVPSKPSGDHDDYQFSPDGTTIAFSLRLAGKTEAWSTNFDIYEVPAAGGKAPRNLTADNPAWDGKPTFSPDGHTLAYLAMDRAGFEADRFHVVLMDIASGKKRTLANNWDHSVADYAWSSDSKTLYAGADDVGQHRVFAIDVASGSVKSLTGPGWVSGFDVKHDMLLVTYQNLASAAQLFKLKLGSPEMTQLTHNNAQALADVKFGEYEQFSFAGHNGDKVYGYVMKPWNAKEGGKYPIAFIVHGGPQGSFGNEWSYRWNPQIYAGAGYASVFIDFHGSTGYGQKFTDAISQDWGGAPLEDLQKGLEAAVKQFPWLDRGHSCALGASYGGYMMNWIEGNWPDGFRCIVNHDGVFDNRAMYYSTDELWFNEWENGGTYYKNPQGHEKFNPVNFVTNWKTPMLVVQGEQDFRIPFTQAMGAFTALQRQGIESKFLVFPDENHWVLKPANSVLWHHTVLDWLDQHLKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GU85</accession>
    <name>A0A2S9GU85_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">LysR substrate binding domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3963</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000025">
        <property type="protein sequence ID" value="PRC91292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91292">
        <property type="protein sequence ID" value="PRC91292"/>
        <property type="gene ID" value="S2091_3963"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="7"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="301" mass="34390" checksum="C0562BE7097C467E" modified="2018-07-18" version="1">MLDPRNIDLNLLVVFNEIFQEQQISSVAKRLNLSQPAVSNALARLRRTFDDQLFVRTKEGMQPTPFAEQLAEPIRLALNGLTEAMNVHEKFDAANSNRHFNIALTDVAELYFMPKLINHCTLLAPQVRISTERTARLDLMAEMGAGKIDVAIGAFNEVSEALYQRRLFKQNYVVMMRAEHPLAGEALSIERFMAAEHLMVASNESPYDKINQDLEKAGILDRVKFSVPHFTAVPYIISNSDLLVTVPQKLAESTALPFKLHYQHHPLNLPDLQTNIFWHRRYHQDQGNQWLRSLISEVFAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUC6</accession>
    <name>A0A2S9GUC6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Plasmid stabilization system protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4008</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000025">
        <property type="protein sequence ID" value="PRC91337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91337">
        <property type="protein sequence ID" value="PRC91337"/>
        <property type="gene ID" value="S2091_4008"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2310.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007712">
        <property type="entry name" value="RelE/ParE_toxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035093">
        <property type="entry name" value="RelE/ParE_toxin_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05016">
        <property type="entry name" value="ParE_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-1277">Toxin-antitoxin system</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="84" mass="9798" checksum="25C7D27CAFDF0DEC" modified="2018-07-18" version="1">MELLWTNKALSDLARHHEFLTAVNKLAAARTIRALTAAPSSLLVNPRIGERLEEFELREVRRIFVGRYEMRYEILASTIYLLRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUH0</accession>
    <name>A0A2S9GUH0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Type II toxin-antitoxin system</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3899</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the phD/YefM antitoxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000024">
        <property type="protein sequence ID" value="PRC91354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91354">
        <property type="protein sequence ID" value="PRC91354"/>
        <property type="gene ID" value="S2091_3899"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036165">
        <property type="entry name" value="YefM-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143120">
        <property type="entry name" value="SSF143120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009981"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="78" mass="8803" checksum="DA850096DCAE8B5D" modified="2018-07-18" version="1">MNSNQVSKSEFKAKALEFFRQVEASGQSVIVTDHGKPTLEVRPYRSTEHLPLDVLRGSVVRYDNPTDPIADDEWEAAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUJ8</accession>
    <name>A0A2S9GUJ8_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Glutamate 5-kinase</fullName>
            <ecNumber evidence="8">2.7.2.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Gamma-glutamyl kinase</fullName>
            <shortName evidence="8">GK</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">proB</name>
        <name evidence="10" type="ORF">S2091_3934</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>ATP + L-glutamate = ADP + L-glutamyl 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:14877"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58274"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.2.11"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="8">Amino-acid biosynthesis; L-proline biosynthesis; L-glutamate 5-semialdehyde from L-glutamate: step 1/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the glutamate 5-kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.2.11" evidence="8"/>
    <dbReference type="EMBL" id="PUGF01000024">
        <property type="protein sequence ID" value="PRC91389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91389">
        <property type="protein sequence ID" value="PRC91389"/>
        <property type="gene ID" value="S2091_3934"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00098">
        <property type="reaction ID" value="UER00359"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004349">
        <property type="term" value="F:glutamate 5-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055129">
        <property type="term" value="P:L-proline biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04242">
        <property type="entry name" value="AAK_G5K_ProB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00456">
        <property type="entry name" value="ProB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036393">
        <property type="entry name" value="AceGlu_kinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001048">
        <property type="entry name" value="Asp/Glu/Uridylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041739">
        <property type="entry name" value="G5K_ProB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001057">
        <property type="entry name" value="Glu/AcGlu_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011529">
        <property type="entry name" value="Glu_5kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005715">
        <property type="entry name" value="Glu_5kinase/COase_Synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019797">
        <property type="entry name" value="Glutamate_5-kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002478">
        <property type="entry name" value="PUA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036974">
        <property type="entry name" value="PUA_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00696">
        <property type="entry name" value="AA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01472">
        <property type="entry name" value="PUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000729">
        <property type="entry name" value="GK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00474">
        <property type="entry name" value="GLU5KINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00359">
        <property type="entry name" value="PUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53633">
        <property type="entry name" value="SSF53633"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="SSF88697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01027">
        <property type="entry name" value="proB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00902">
        <property type="entry name" value="GLUTAMATE_5_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3 8" id="KW-0641">Proline biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PUA" evidence="9">
        <location>
            <begin position="281"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="14"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="54"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="141"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="153"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="173"/>
            <end position="174"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC91389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="374" mass="40216" checksum="1F3962C4E844D59A" modified="2018-07-18" version="1">MSTELQSSKRLIIKVGSSLVTNDGRGLDHAAIQNWAAQIASLRNMGKEVVLVSSGAIAEGMLRLGFVKRPTEIDELQACAAVGQMGLAQIYESSFRQHNLGTAQVLLTHADLADRERYLNARSTLRTLLRFGIVPIINENDTVVTDEIKLGDNDTLGALVANLIEADALIILTDQTGLFSADPRKNPDAEFIHRATAGDPKLEEMAGGAGSSIGRGGMLTKILAAKRAANSGAHTIIAWGREQNVLTRLLQGELIGTHLVAQTEPLAARKQWLQDHLQTSGQFILDDGAVNKLLNEGKSLLPIGVLEVRGEFGRGAAVTCLNQAGVAIARGLSNYSSSDARRIKRHASSEIINILGFMEASELIHRDNLVLLNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUM9</accession>
    <name>A0A2S9GUM9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3852</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000023">
        <property type="protein sequence ID" value="PRC91437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91437">
        <property type="protein sequence ID" value="PRC91437"/>
        <property type="gene ID" value="S2091_3852"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="36"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="89"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="118" mass="12767" checksum="9C050D92D50A8AB9" modified="2018-07-18" version="1">MTDPNQGVTVHLGVEEANVGPTPIEEAQARSLTADMIFRGIMVVVVCVIFSWLNWNVMSFVREAFASDNAGLIAKPPMLPADRLITPNVVMAMIGATVVQTGIGFIAIMSYLFPKRTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUN5</accession>
    <name>A0A2S9GUN5_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ABC_trans_aux domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3839</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000023">
        <property type="protein sequence ID" value="PRC91424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91424">
        <property type="protein sequence ID" value="PRC91424"/>
        <property type="gene ID" value="S2091_3839"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005586">
        <property type="entry name" value="ABC_trans_aux"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03886">
        <property type="entry name" value="ABC_trans_aux"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC_trans_aux" evidence="1">
        <location>
            <begin position="39"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="227" mass="24959" checksum="5919EE7FDD23D245" modified="2018-07-18" version="1">MNRESYSQLFKCLINTLPIILLSACSALHPIETAPPTFYSLDYPTAKSNQAKPTLPDYAPTLLVNPPVAASGFDSQRIIYTRVAHQLEYFAHSEWIDTPARMIAPLIVDALANSGAFRAVAPATSAAAGGLRLNTEIVRLQHDFSTQPSQLRFTIRAYVLDNATRKVLAWHEFDEVVVAASDTPYDGIVAANQAVQIGLQELTRFCVDTTRQWQASKDAEHSNGTLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUT2</accession>
    <name>A0A2S9GUT2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3873</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000023">
        <property type="protein sequence ID" value="PRC91458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91458">
        <property type="protein sequence ID" value="PRC91458"/>
        <property type="gene ID" value="S2091_3873"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015673981" evidence="1">
        <location>
            <begin position="29"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="107" mass="12088" checksum="B639B71DDF41F599" modified="2018-07-18" version="1">MNINLTNSIMTSVPIICLFILSISASYAQSNQDASIAQPGDPARWYQEDMTPHGYFLTLKKEAMNVYQDSSKKCMSEEKSNRKQCMIEAKNTFKQDMDAAKEKSGSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUX1</accession>
    <name>A0A2S9GUX1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ABC-type Fe3+-hydroxamate transport system periplasmic component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3810</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000022">
        <property type="protein sequence ID" value="PRC91532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91532">
        <property type="protein sequence ID" value="PRC91532"/>
        <property type="gene ID" value="S2091_3810"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002491">
        <property type="entry name" value="ABC_transptr_periplasmic_BD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01497">
        <property type="entry name" value="Peripla_BP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50983">
        <property type="entry name" value="FE_B12_PBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015528949" evidence="1">
        <location>
            <begin position="21"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="domain" description="Fe/B12 periplasmic-binding" evidence="2">
        <location>
            <begin position="40"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="293" mass="31723" checksum="81F2B1CB7B7848FC" modified="2018-07-18" version="1">MNIVKLIGGLVCLIAVTANAAITVQDDDGKTVTLQKPAQRIISLAPHVTELLFAAGGGDLIKGVVSYSDYPEAAKLIPIIGDNREVDIERIIALKPDLLVIWRHGSSDKQVEQLRKLGVPLFYSEPHKLVDIPNNIRVLGQLMGTEKQANSVAAELSQQLTALTAKYANRSPVRLFYQVWDKPLFTLNGQHIVSDAIRVCGGVNIFANLKTTAPNVGIEAVLQEDPEAIIGTAEKSPSDGGVAMWKRYPGMTAVKRANLFLVDGNLINRSGPRMIAGTAALCEKLDLARSNRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUX9</accession>
    <name>A0A2S9GUX9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3792</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000022">
        <property type="protein sequence ID" value="PRC91514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91514">
        <property type="protein sequence ID" value="PRC91514"/>
        <property type="gene ID" value="S2091_3792"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="103" mass="12334" checksum="9A4058134AEB872F" modified="2018-07-18" version="1">MRLDVVEFSRPVVDRQLPTFFASPKKVGQKRRPRYFGNPDFSKKKREKFETRLRLKQRTFLILFPLEKSAELEVGVGQNQLQRQLQKQLHDHESFTFTLNKKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GV52</accession>
    <name>A0A2S9GV52_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative nucleic-acid-binding protein contains PIN domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3715</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000021">
        <property type="protein sequence ID" value="PRC91599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91599">
        <property type="protein sequence ID" value="PRC91599"/>
        <property type="gene ID" value="S2091_3715"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002716">
        <property type="entry name" value="PIN_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01850">
        <property type="entry name" value="PIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="SSF88723"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PINc" evidence="1">
        <location>
            <begin position="4"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="131" mass="14395" checksum="A433B0C20EBC46BF" modified="2018-07-18" version="1">MIGLDTNVLVRYIAQDEPQQSAIATTLITSLSSENPGYITIVALTELVWVMQSCYNATKPEVITILDMLLKTKELVVENAETAIKALTIFTRSNADFSDCLIERSAHKAGCDYTATFDKKAAKTTGMRLQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVD2</accession>
    <name>A0A2S9GVD2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lysophospholipase L1 and related esterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3611</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000020">
        <property type="protein sequence ID" value="PRC91673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91673">
        <property type="protein sequence ID" value="PRC91673"/>
        <property type="gene ID" value="S2091_3611"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013830">
        <property type="entry name" value="SGNH_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13472">
        <property type="entry name" value="Lipase_GDSL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SGNH_hydro" evidence="1">
        <location>
            <begin position="42"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="219" mass="23999" checksum="AE471EF79244B4B1" modified="2018-07-18" version="1">MQKFRLTEKWFKKLSWVLFLTILFTALSGFRTAYSAPKTVLVLGDSLSAEYGLARGTGWVALLEQRIQDKKLAVQVINASISGDTTSGGLARINDLLKKHQPTTVIIELGGNDGLRGLSLTASEQNFRAMIAASKTAKANVLLVGMQIPPNYGRTYTDQFSAMYGKIAKETKIPLVPFLLAGVADKPELFQADRIHLIAAAHPSILNNVWPYLLPLISK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVG5</accession>
    <name>A0A2S9GVG5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_3655</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000020">
        <property type="protein sequence ID" value="PRC91717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91717">
        <property type="protein sequence ID" value="PRC91717"/>
        <property type="gene ID" value="S2091_3655"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004638">
        <property type="entry name" value="EmrB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00711">
        <property type="entry name" value="efflux_EmrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="46"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="76"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="101"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="134"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="164"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="195"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="226"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="265"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="296"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="329"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="353"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="400"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="429"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="10"/>
            <end position="458"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC91717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="468" mass="50686" checksum="990C161AC2C047C9" modified="2018-07-18" version="1">MMESVVKRYLPWVVASALFMEQLDSTIVNTAVPAMAASLNVTPLSLKAVVTSYILSLAVCIPVSGWIADRYGTRRVFSYAVTIFTIASILCGLSMSVPMLVAARILQGIGAALMLPVGRITIVRTFPKSELLAAMNFVIIPALIGPLLGPLVGGLIVHWLSWRVIFFVNIPVGLVALYLSHRFMPNYFGEEQRPLDVLGLVLFGTGTALLSWLLEIFGEHSLDSTSVGVLFVVAVVLLATYVWHARQHAYPLLNLALFKIRTFRVSVAGGFITRLGIGALPFLLPLLYQLGLGLPAWQSGLLMMPAALAAMGMKMIASKVLARLGYRRILMVNTVMIGCTISCFSLITPNTPIALIVMLGFTMGFFNSLQFTCMNSMAYADIQITDSSMASTIASSLQQLSMSFGLACGLLITSWFLDGLPQTNHPAILSALHHAFVAMGMLTILSALTFTTLQARDGENVSRAKIEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVJ8</accession>
    <name>A0A2S9GVJ8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Dehydrogenases with different specificities (Related to short-chain alcohol dehydrogenases)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3489</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000019">
        <property type="protein sequence ID" value="PRC91734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91734">
        <property type="protein sequence ID" value="PRC91734"/>
        <property type="gene ID" value="S2091_3489"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="257" mass="27658" checksum="147C19068A330D76" modified="2018-07-18" version="1">MNTQFNGKKLLVVGGTSGMGLQTARMVLEQGGSVVIVGHRQDKAEEARKELSLLGSVTALTADLSRAEDVRRLLDNIDEHHKDIDLLVNAAGVFFPKAFLDHTESDYEQYLTLNKAFFFITQKVVANLVTSERSGAIVNIGSMWAKQAIAATPSSAYSMAKAGLHSLTQHLAMELASKKIRVNAVAPAVVETPIYEGFIPKAEVHGALQGFNSFHPIGRVGTPQDIAEAIIFLLSEKAAWVTGAVWDVDGGVMAGRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVW5</accession>
    <name>A0A2S9GVW5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="9">TonB-dependent Receptor Plug Domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_3419</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000018">
        <property type="protein sequence ID" value="PRC91863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91863">
        <property type="protein sequence ID" value="PRC91863"/>
        <property type="gene ID" value="S2091_3419"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039423">
        <property type="entry name" value="TonB-dep_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32552">
        <property type="entry name" value="PTHR32552"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="3 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0675">Receptor</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="2 5" id="KW-0798">TonB box</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015767689" evidence="6">
        <location>
            <begin position="31"/>
            <end position="821"/>
        </location>
    </feature>
    <feature type="domain" description="Plug" evidence="8">
        <location>
            <begin position="66"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="7">
        <location>
            <begin position="296"/>
            <end position="815"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC91863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="821" mass="88743" checksum="A3F22F7264A65909" modified="2018-07-18" version="1">MKFRQKNLAFSISLALLTGALGGTATTANAAEQTADNPAPAPAASAPEDASIAVITITAQNRSQQMQEVPISLQVITNDQITKLAANNLSDLNGYIPGLVVNGSQPTQPGYSIRGIGTGDFGIGTDSPVGIYVDGVYTGKTGGALMNFNDVERVEVLKGPQGTLFGRNSAAGAISVVTKGPSNEFENDANIRFGQYGERNVDAMLNVPLSDTVALRFTFVDNKSRGWLNDSATGESMNDTGDWGTRATLRWNAPGHTKVIFSWEHESLNQDARPDIGLVPLALQTPAPPFPANPNTYLNPITAPAYNNSDGNLEKRLFNGATLRVEYPFEWGTFDSTTAYRHFNSSNIESNTGSNLVGSYLTTGNLENNTTWQQEFKLSGKNDTVDWLTGVSMFSESAQQTSQVNLNTDTLNNVFNNLYSFPVYGLLNDAAVALGIPVKLFGNSWQENMFNSETSKSYAIYGDAIWHVAPKLNLTTGVRFSYDSKNFSWYNPPRVAPGVDTALATLNQVNFFPNLVQAGAITQAQANQVIGAMTQNIEYGNALSLNAPYSMSNSWTDVSPRVVLDYKLSPDVMVYGSVTKGYQSGGFNAQLVAGAYQPEIVWNYEAGLKSYFPEQHLLINSSLFLYKFSNLQSLSLVPSGSPIPQYQVTSSNQSAVGVDTDVRWQPTHNLRMFAVAEYIDQDYGNYTAADGTNLNNQPTGTPLWTIAGGADYTQRNIWDGSINYSLQHAYTGPVRCNADAVAQGACLSTPTFTLGGSTQRTDGRIGWDAGNHKWGVAVYVNNLFNNRYVTGIDNTALTVLGTPAANISAPRIVGMQLHVSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GW01</accession>
    <name>A0A2S9GW01_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3392</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000018">
        <property type="protein sequence ID" value="PRC91836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91836">
        <property type="protein sequence ID" value="PRC91836"/>
        <property type="gene ID" value="S2091_3392"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="221" mass="23706" checksum="B9E9E37064AF6391" modified="2018-07-18" version="1">MAQTVMRNEDNRPQANALRRLQSLSENAPQMSQLQTLQAKAANASSLTKWHSTEFVAQRFRGATGTAEAAAEVPMTLNNAFVKNHVAEDAQEAINKTNQRILDVNEPAAMKTGSLANSLAPLATWETAINGSEVVLPPQDDWGGEYGFDDTTTYNHKLTGFTVKGWEAKGKANAVIATEKEISKYVGGEWKVAGGTTTNGSNVNTSADATHVTVDIDHCTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GW46</accession>
    <name>A0A2S9GW46_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3289</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000017">
        <property type="protein sequence ID" value="PRC91947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91947">
        <property type="protein sequence ID" value="PRC91947"/>
        <property type="gene ID" value="S2091_3289"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038573">
        <property type="entry name" value="BrnT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007460">
        <property type="entry name" value="BrnT_toxin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04365">
        <property type="entry name" value="BrnT_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="92" mass="10878" checksum="FE76242580CC9D17" modified="2018-07-18" version="1">MEISFDPVKNERNISDRGLSFSLVEQLNWSSALIEEDVRKDYGERRYLALGLIEYRLHAVVFTPRADKMHVISLRKANQREVNYYDEQKTKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GW77</accession>
    <name>A0A2S9GW77_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_3319</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000017">
        <property type="protein sequence ID" value="PRC91977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91977">
        <property type="protein sequence ID" value="PRC91977"/>
        <property type="gene ID" value="S2091_3319"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1060.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004017">
        <property type="entry name" value="Cys_rich_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021872">
        <property type="entry name" value="DUF3483"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009051">
        <property type="entry name" value="Helical_ferredxn"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02754">
        <property type="entry name" value="CCG"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11982">
        <property type="entry name" value="DUF3483"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13183">
        <property type="entry name" value="Fer4_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="67"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="96"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="128"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="154"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="5">
        <location>
            <begin position="227"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="5">
        <location>
            <begin position="300"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC91977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="623" mass="67593" checksum="F9D6D285A7EBF935" modified="2018-07-18" version="1">MLALVLTVSFWTSVAIFLLGLLMRARLWRNGRAAPLALGNLFSIPKRYFVDLHNVVAREPFIARAHAMVAGGAVLALLIIAINYGLAQYSPLLDRVLLLASTLMLFGSALMAWRRLAPPTRLSRGPWMRLPFTLMAFAIGSGLAAWLAPQGAQAPALIVIVLLLIGSAELALGIGMGGPMKHAVAGLLNLAFHPRQDRFAGKRSTNLRLLDLSKGDYGVAKPADFSWNRLLQFDACVQCGKCEAACPALAAGQPLNPKKLIQDMVVGLASKDDSAYAGTPYPGKPVGQHSGAPHLAIIPGLVDADTIWSCTTCRACVQECPMLIEHVDAVIDIRREQTLVQGAVPGKGAQVLENLRHTETVGGFAKSARYNWAIDLNVPTLIPGQKTDWLLIAGEGAFDMRYQRALRSLVRVLQHAGVDFAVLGAAEIDSGDLARRLGDEATFQELAKNNIAMLGKRAFKHIVTPDPHVFHCLKNEYPALGGHYDVWHHSGLIAHLFKERRIRLKKTPLLSAPLTYHDPCYLGRYNGEFDAPREVLEALGHSVREMERSREKARCCGGGGGAPFTDIPGTTRIPDIRIIDANSIGAEIVAVACPNCTFMLEGVVGPRPEVMELAELVEQRLGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWA5</accession>
    <name>A0A2S9GWA5_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">CDP-diacylglycerol--serine O-phosphatidyltransferase</fullName>
            <ecNumber evidence="4">2.7.8.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Phosphatidylserine synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_3344</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a CDP-1,2-diacyl-sn-glycerol + L-serine = a 1,2-diacyl-sn-glycero-3-phospho-L-serine + CMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16913"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:57262"/>
            <dbReference type="ChEBI" id="CHEBI:58332"/>
            <dbReference type="ChEBI" id="CHEBI:60377"/>
            <dbReference type="EC" id="2.7.8.8"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the CDP-alcohol phosphatidyltransferase class-I family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.8" evidence="4"/>
    <dbReference type="EMBL" id="PUGF01000017">
        <property type="protein sequence ID" value="PRC92002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92002">
        <property type="protein sequence ID" value="PRC92002"/>
        <property type="gene ID" value="S2091_3344"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003882">
        <property type="term" value="F:CDP-diacylglycerol-serine O-phosphatidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004533">
        <property type="entry name" value="CDP-diaglyc--ser_O-PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000462">
        <property type="entry name" value="CDP-OH_P_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043130">
        <property type="entry name" value="CDP-OH_PTrfase_TM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01066">
        <property type="entry name" value="CDP-OH_P_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00473">
        <property type="entry name" value="pssA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00379">
        <property type="entry name" value="CDP_ALCOHOL_P_TRANSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="15"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="44"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="83"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="144"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="171"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00032361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC92002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="205" mass="22536" checksum="D7B4C35CBA31D056" modified="2018-07-18" version="1">MTAPKPFSMIREFHLADWFTLSNAFCGVGALFSAMTYLQTGDTMHLYFACGLIPFALLFDVLDGRIARWRQQSSAMGRELDSLADVISFGVAPAVIAYACGMQGLYDRIVLLFFVAAGVSRLARYNVTAEELSDGGDKVKYFEGTPIPTSLVLVIIMALAVWQGALGQQMWFGVLFVGGFQFHPLVLLYAISGSLMISRIRIPKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWS9</accession>
    <name>A0A2S9GWS9_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase</fullName>
            <shortName evidence="7">UDP-N-acetylglucosamine acyltransferase</shortName>
            <ecNumber evidence="7">2.3.1.129</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">lpxA</name>
        <name evidence="9" type="ORF">S2091_3074</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>a (3R)-hydroxyacyl-[ACP] + UDP-N-acetyl-alpha-D-glucosamine = a UDP-3-O-[(3R)-3-hydroxyacyl]-N-acetyl-alpha-D-glucosamine + holo-[ACP]</text>
            <dbReference type="Rhea" id="RHEA:67812"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="Rhea" id="RHEA-COMP:9945"/>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78827"/>
            <dbReference type="ChEBI" id="CHEBI:173225"/>
            <dbReference type="EC" id="2.3.1.129"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Glycolipid biosynthesis; lipid IV(A) biosynthesis; lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 1/6.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homotrimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the transferase hexapeptide repeat family. LpxA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.129" evidence="7"/>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92158">
        <property type="protein sequence ID" value="PRC92158"/>
        <property type="gene ID" value="S2091_3074"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00359">
        <property type="reaction ID" value="UER00477"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008780">
        <property type="term" value="F:acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009245">
        <property type="term" value="P:lipid A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03351">
        <property type="entry name" value="LbH_UDP-GlcNAc_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00387">
        <property type="entry name" value="LpxA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029098">
        <property type="entry name" value="Acetyltransf_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037157">
        <property type="entry name" value="Acetyltransf_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018357">
        <property type="entry name" value="Hexapep_transf_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010137">
        <property type="entry name" value="Lipid_A_LpxA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43480">
        <property type="entry name" value="PTHR43480"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13720">
        <property type="entry name" value="Acetyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000456">
        <property type="entry name" value="UDP-GlcNAc_acltr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01852">
        <property type="entry name" value="lipid_A_lpxA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00101">
        <property type="entry name" value="HEXAPEP_TRANSFERASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 9" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 7" id="KW-0441">Lipid A biosynthesis</keyword>
    <keyword evidence="1 7" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="5 7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 7 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Acetyltransf_11" evidence="8">
        <location>
            <begin position="176"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF13720"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC92158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="262" mass="28415" checksum="85FA21963A1D7C5F" modified="2018-07-18" version="1">MSKIHSTAIIAKEACLDSSVEVGAYSIIGPHVQIAAGTKIGPHVVLEGHTTIGRDNTFFQFSSIGAAPQDKKYAGEPTRLEIGDRNTVREFCTFNLGTVQDADVTRIGHDNLMMAYVHIAHDCQVGNNTIFANNASIAGHVEIGDWVILGGFAGVHQFCKIGAHAMLGMNTSLTQDVPPFVILSGNPAAVHGLNLEGLKRRGFTREQLNAIRQIYKLLYKSGLTLEEAKLAMQAALAEHPAAQQQIQQMQTFLERSTRGIVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWV3</accession>
    <name>A0A2S9GWV3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3115</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92199">
        <property type="protein sequence ID" value="PRC92199"/>
        <property type="gene ID" value="S2091_3115"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="9"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="80" mass="9314" checksum="7C770651C1406E26" modified="2018-07-18" version="1">MNAHEIKEALLWCVAINYAVLFIWFGVLILAHDLLYRLHTRWFKLSVETFDSIHYAGLAIYKIGIILFNLVPLIALYFSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWZ5</accession>
    <name>A0A2S9GWZ5_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">FAD assembly factor SdhE</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_3102</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SdhE FAD assembly factor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92186">
        <property type="protein sequence ID" value="PRC92186"/>
        <property type="gene ID" value="S2091_3102"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.250">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005631">
        <property type="entry name" value="SDH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036714">
        <property type="entry name" value="SDH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03937">
        <property type="entry name" value="Sdh5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109910">
        <property type="entry name" value="SSF109910"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00019418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC92186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="89" mass="10268" checksum="95EDB5838F66DB9E" modified="2018-07-18" version="1">MLITHQADPIKRARLRWRARRGLLENDLILTRFLDANEATLTDDEVEAFSKLMELSDNDLMGLILERNEPTGELDDPVVHTLIQRLRSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXB4</accession>
    <name>A0A2S9GXB4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3023</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92364">
        <property type="protein sequence ID" value="PRC92364"/>
        <property type="gene ID" value="S2091_3023"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032129">
        <property type="entry name" value="DUF5056"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16479">
        <property type="entry name" value="DUF5056"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="62"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="98"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="129" mass="14448" checksum="CB68E431E5B8CA27" modified="2018-07-18" version="1">MENQPKINSAINLDSDSAEQDAWLETLLQEDASESHYLDDNGFSTRVMSSLPRSRASKDYRWILWIAASLGILIGGFWLSGFELYFQALSSSFEGNATSLNCLIILLSPIALLYWFAATLFKCPNCDLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXE4</accession>
    <name>A0A2S9GXE4_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">Cyclic pyranopterin monophosphate synthase</fullName>
            <ecNumber evidence="3 5">4.6.1.17</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Molybdenum cofactor biosynthesis protein C</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">moaC</name>
        <name evidence="7" type="ORF">S2091_2769</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>(8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate = cyclic pyranopterin phosphate + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:49580"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:59648"/>
            <dbReference type="ChEBI" id="CHEBI:131766"/>
            <dbReference type="EC" id="4.6.1.17"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 5">Cofactor biosynthesis; molybdopterin biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homohexamer; trimer of dimers.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the MoaC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.6.1.17" evidence="3 5"/>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92394">
        <property type="protein sequence ID" value="PRC92394"/>
        <property type="gene ID" value="S2091_2769"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00344"/>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061799">
        <property type="term" value="F:cyclic pyranopterin monophosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006777">
        <property type="term" value="P:Mo-molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01420">
        <property type="entry name" value="MoaC_PE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.640">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01224_B">
        <property type="entry name" value="MoaC_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023045">
        <property type="entry name" value="Mo_CF_biosynth-C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036522">
        <property type="entry name" value="MoaC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002820">
        <property type="entry name" value="Mopterin_CF_biosynth-C_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01967">
        <property type="entry name" value="MoaC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55040">
        <property type="entry name" value="SSF55040"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00581">
        <property type="entry name" value="moaC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 5" id="KW-0501">Molybdenum cofactor biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MoaC" evidence="6">
        <location>
            <begin position="24"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="84"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="120"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC92394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="171" mass="18041" checksum="4163CD762847DC7B" modified="2018-07-18" version="1">MSNSPIKSDQSELTHFDASGQAHMVDVSSKAATHRVARASGSITMQPATFALIASGSAKKGDVLGVAKIAAIMAAKRTSDLIPLCHPLAITRVTVDFELVDNSVICTAQVETIGPTGVEMEALTAVQIGLLTIYDMTKAVDRGMVMTNIRVLEKHGGKSGDWVAEIPHTQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXJ8</accession>
    <name>A0A2S9GXJ8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">RDD family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_2761</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92386">
        <property type="protein sequence ID" value="PRC92386"/>
        <property type="gene ID" value="S2091_2761"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010432">
        <property type="entry name" value="RDD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06271">
        <property type="entry name" value="RDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="44"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="99"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="146"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="domain" description="RDD" evidence="6">
        <location>
            <begin position="9"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF06271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC92386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="187" mass="21602" checksum="440DE8D481774BAF" modified="2018-07-18" version="1">MLEENSIIYSGYWRRLSGHVLDVIFIVVFFWITDSLSGGIKSLAALIVVFQGMTYYLYTLFFHASYGQTFGKRIMGIKVVSDDGKPIGFQKSFRRNIPLFFESLPWIIGTLFALSQISNEQFHSLFLQPKLYSITLESLRPDWHNTVQIVFAALIFMELMIMFITKKRQTIHDLIGSTIVIRNSTLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXK9</accession>
    <name>A0A2S9GXK9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2771</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92396">
        <property type="protein sequence ID" value="PRC92396"/>
        <property type="gene ID" value="S2091_2771"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021332">
        <property type="entry name" value="DUF2944"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11161">
        <property type="entry name" value="DUF2944"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="195" mass="21905" checksum="1D3F43D36748BFA7" modified="2018-07-18" version="1">MDKQVQLAMAKWPNVPHCYGWLGLDARGAWRMRDQHAQESDLLGSKIANVILRGFIDRNYQSDDAGRYFFQNGPQRVYVELQSTPYIAHSDPQSGWVLHTGTALTNCDAVWMTSDGHLLLQSAAILAQVDDRDMVDAMACVYLNDQPASDEQVLAWLENPHAGLTFRFQQQSIPITLTSLTELAKTHPFVAHPQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXM5</accession>
    <name>A0A2S9GXM5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycine/D-amino acid oxidases (Deaminating)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2850</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92475">
        <property type="protein sequence ID" value="PRC92475"/>
        <property type="gene ID" value="S2091_2850"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DAO" evidence="1">
        <location>
            <begin position="4"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="372" mass="40047" checksum="BCCBA24296E5143A" modified="2018-07-18" version="1">MSTDVLVIGAGIVGAACARALQQRGLSVALVDATTPGAGVTAAGMGHLVVLDHDETELCLFSMRLWREFNDAHPEIGEFSRCGTLWVAENETQLQEALQRAERYSQRGWNAEFIQGKNMRQLEPQLRSGLCGGVLVSNDAVVFPPKVAQFLAMQCMQFGGKVHLGQRVVALTDGAVELANGVSLTAKHIVLATGVETAQLLPEVPVFARKGHLAITDRYPGLLQHQIVNMNYGQIESGSDNLAVAANVQARPNGQWLVGSCRQDGQLDTKLDFSVLSKVLLSAIELLPCLSEMRILRAWAGMRPATPDGHPLIGPHPFRPGLWLATGHEGLGITTAFATAEILADQIMRQPGSFDASAYLPSRFSMKVDHAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXU2</accession>
    <name>A0A2S9GXU2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2602</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92547">
        <property type="protein sequence ID" value="PRC92547"/>
        <property type="gene ID" value="S2091_2602"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011712">
        <property type="entry name" value="Sig_transdc_His_kin_sub3_dim/P"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07730">
        <property type="entry name" value="HisKA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="61"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="125"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="150"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="domain" description="HisKA_3" evidence="2">
        <location>
            <begin position="193"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="383" mass="42675" checksum="2B0D615DDECA4B9F" modified="2018-07-18" version="1">MRANFPSKRSRAQNNMHELKRILTGPWVPKYHGKAPYFWLLMLVFFAWKYLFTTPSISENVLFWLTIVVFVPLYFGSLWVKNLRSVFFILSVCMLGVLWAPTNFGASVFFIFSAALCSRIEQSRLAFGMLAIVLAILGVVVLTFHLPSNFWFPSLIVSISVGATNILQSNLKRSREQLLRTQEEVAHMATIAERERISRDLHDLLGHTLSLITLKAELAGKLLARDVQACQQEIKDIENSARHALSEVRSAVSGYRQVGFSHELNNARNCLSAANIQLSTQIQTLPLTAATENVLALTLREAVTNIVRHANATHCEIKLELEMDFIVLQIQDNGVGVKNVAAIQQGNGLIGMHERVNATGGRLALKVNNGLALQLFIPMGVAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXW8</accession>
    <name>A0A2S9GXW8_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">dCTP deaminase</fullName>
            <ecNumber evidence="3">3.5.4.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Deoxycytidine triphosphate deaminase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">dcd</name>
        <name evidence="5" type="ORF">S2091_2605</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the deamination of dCTP to dUTP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>dCTP + H(+) + H2O = dUTP + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:22680"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:61481"/>
            <dbReference type="ChEBI" id="CHEBI:61555"/>
            <dbReference type="EC" id="3.5.4.13"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Pyrimidine metabolism; dUMP biosynthesis; dUMP from dCTP (dUTP route): step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homotrimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the dCTP deaminase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.13" evidence="3"/>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92550">
        <property type="protein sequence ID" value="PRC92550"/>
        <property type="gene ID" value="S2091_2605"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00610">
        <property type="reaction ID" value="UER00665"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008829">
        <property type="term" value="F:dCTP deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006226">
        <property type="term" value="P:dUMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006229">
        <property type="term" value="P:dUTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07557">
        <property type="entry name" value="trimeric_dUTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00146">
        <property type="entry name" value="dCTP_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011962">
        <property type="entry name" value="dCTP_deaminase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029054">
        <property type="entry name" value="dUTPase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036157">
        <property type="entry name" value="dUTPase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033704">
        <property type="entry name" value="dUTPase_trimeric"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00692">
        <property type="entry name" value="dUTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51283">
        <property type="entry name" value="SSF51283"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02274">
        <property type="entry name" value="dCTP_deam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 3" id="KW-0546">Nucleotide metabolism</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="dUTPase" evidence="4">
        <location>
            <begin position="82"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="3">
        <location>
            <position position="137"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="111"/>
            <end position="116"/>
        </location>
        <ligand>
            <name>dCTP</name>
            <dbReference type="ChEBI" id="CHEBI:61481"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="135"/>
            <end position="137"/>
        </location>
        <ligand>
            <name>dCTP</name>
            <dbReference type="ChEBI" id="CHEBI:61481"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="156"/>
        </location>
        <ligand>
            <name>dCTP</name>
            <dbReference type="ChEBI" id="CHEBI:61481"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="170"/>
        </location>
        <ligand>
            <name>dCTP</name>
            <dbReference type="ChEBI" id="CHEBI:61481"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="176"/>
        </location>
        <ligand>
            <name>dCTP</name>
            <dbReference type="ChEBI" id="CHEBI:61481"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="180"/>
        </location>
        <ligand>
            <name>dCTP</name>
            <dbReference type="ChEBI" id="CHEBI:61481"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC92550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="188" mass="21267" checksum="68BCC825C3AB9317" modified="2018-07-18" version="1">MSIKSDAWIRRMAQETKMIEPFEPGQVRVENGQKIVSYGTSSYGYDIRCANEFKIFTNINSTIVDPKNFDEKSFVDFQGDVCIIPPNSFALARTMEYFRIPRNVLTICLGKSTYARCGIIVNVTPFEPEWEGYVTLEFSNTTPLPAKIYAGEGCAQVLFFESDEVCEMSYKDRNGKYQGQVGVTLPKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXW9</accession>
    <name>A0A2S9GXW9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">N-acyl-D-aspartate/D-glutamate deacylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2614</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92559">
        <property type="protein sequence ID" value="PRC92559"/>
        <property type="gene ID" value="S2091_2614"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016811">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013108">
        <property type="entry name" value="Amidohydro_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023100">
        <property type="entry name" value="D-aminoacylase_insert_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07969">
        <property type="entry name" value="Amidohydro_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="SSF51338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydro_3" evidence="1">
        <location>
            <begin position="48"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="domain" description="Amidohydro_3" evidence="1">
        <location>
            <begin position="334"/>
            <end position="461"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="490" mass="52635" checksum="47B0D8628A18C1DA" modified="2018-07-18" version="1">MSALEFDIVIRNAEVIDGTGSTPYRADIGIANQKIAAIAKPNSLIAPQILNANGLVVAPGFIDVHTHDDREVLDHPAMHPKLTQGVTTVITGNCGISLAPWLADRDIPAPLNLIGQRADYRYASVADYVAAVRAAAPAVNVGILVGHSTLRLNAMSELNCVANQEEIAHMQALLAEGMQAGALGFSSGLFYQTSQAADNGEVITLAKVAAAAGGVYTSHIRDEYNGVLDALKEACDAGLAAQAPVILSHHKCAGPANWGRTVETLAYITERRAQQPLGLDAYPYTAGSTVLDPDYVDGVIRIMLSFSMPYPEMAGRDLADIAADWGVDQKEAARRLHPAGAVYFQMREDDVQRVLSYPHTMIGSDGLPHDSHPHPRLWGAFPRVLGHYCREQKLFTLAEAVHKMTGLSAQHFGLQQRGKIALNYWADLVIFDPATISDLATFSQPKQAAQGIYWVLVNGEVALNADGPTGHRNGQVLNRNSEQLSADVST</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GY34</accession>
    <name>A0A2S9GY34_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2673</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92618">
        <property type="protein sequence ID" value="PRC92618"/>
        <property type="gene ID" value="S2091_2673"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="135" mass="15193" checksum="F0DAD2F928F14F56" modified="2018-07-18" version="1">MNNQYGLDVGYFKTKLSQIIRDVESYTSDEMFRDLTKYAEVVRPVETVKHTGPVAYAPFWIKESGFRATGISAISDTTFTVPLYTCPISNEDVVDVIKKFNSFASSFNDGDSIAQQVRQFNEVQAAINLIESRMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GY43</accession>
    <name>A0A2S9GY43_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2699</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92644">
        <property type="protein sequence ID" value="PRC92644"/>
        <property type="gene ID" value="S2091_2699"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="84" mass="9522" checksum="945A6B1DEF5B430C" modified="2018-07-18" version="1">MKNKQSRNIAVQVNLTPDDYVAISQKFKTLGLSNSGGFQYLAKRFGSQLDMNVSPIVIQKDRRKAPVKCQHFPGRARSRAVMRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GY52</accession>
    <name>A0A2S9GY52_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2696</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92641">
        <property type="protein sequence ID" value="PRC92641"/>
        <property type="gene ID" value="S2091_2696"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="161" mass="18361" checksum="11A71B1126C4E47A" modified="2018-07-18" version="1">MLLHVLYSIAAMKIWNQLEEAERLNKRFYGINRAAFAREHKIKGGQALIYQHINGLRPIGLEAAIAYTKAFQVRLEEISPRLALVAMSALQADRHLIRTHDECAEVRNASESSEKLHLLWISDQETELITNFRKATNSGKLSIMSLSKDMLEKNNETISRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYD4</accession>
    <name>A0A2S9GYD4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2467</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92737">
        <property type="protein sequence ID" value="PRC92737"/>
        <property type="gene ID" value="S2091_2467"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="250" mass="28161" checksum="A1BDA6F44144552D" modified="2018-07-18" version="1">MGPSKTKFTPPPRMSFLEKQAIADAKVSLILEFLSDGEIYTDVAVTSCLLGSSLSSARRTLKRMVKEYSLKTETHLVRSRACQIYGISTQGVALSGNFDCRPFELGKTNPSFITHHLKTQKARLAAIDHGWTDWVPERSIHGKGYLKVPDALVTNSEGFRVAVEIELNIKTTKRYSEICSAHLQSIAKGHWHEVHYLCPEKLLAGVERIFAGIEFVSVKGDRVSIQQKHRQRFKFFCLDAWPIALQKDTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYJ2</accession>
    <name>A0A2S9GYJ2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Radical SAM superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">S2091_2525</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; Fe-Mo cofactor biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the radical SAM superfamily. NifB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92795">
        <property type="protein sequence ID" value="PRC92795"/>
        <property type="gene ID" value="S2091_2525"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00782"/>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009399">
        <property type="term" value="P:nitrogen fixation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005980">
        <property type="entry name" value="Nase_CF_NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43787:SF3">
        <property type="entry name" value="PTHR43787:SF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0535">Nitrogen fixation</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="9">
        <location>
            <begin position="21"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF04055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC92795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="349" mass="39244" checksum="E943462F35D67E74" modified="2018-07-18" version="1">MEIDKYAGFLSRRQLELIIMPTEQCNFRCTYCYEDFEIGKMKDETVQAIKKLITARLSNPSLSELVFSWFGGEPLMAKDIVYELSEFAQKACATSGIQFSSGMTTNAYGLDSATFDNLLKLNVRSYQISIDGDEDEHNKTRKLISGRGTFAKIWSNLLDLKKSKEQFDVMLRIHIHQENVDSLKQLLPKICSEFADDIRFSIFLKAVGNWGGDGVKQMSLTKNADAVKDDMNACLIEHGWFNLRNSAETSDVVTPCYAARSNSFVIRANGMLNKCTVAFSDPRNSVGHINSDGTLFIQSEKIQPFMRGFQSLDKAALRCPMHGMPKIEEVKTIQFAKSINEVLSEISVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYL5</accession>
    <name>A0A2S9GYL5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">RNaseEG: ribonuclease, Rne/Rng family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_2547</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92817">
        <property type="protein sequence ID" value="PRC92817"/>
        <property type="gene ID" value="S2091_2547"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004540">
        <property type="term" value="F:ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019307">
        <property type="entry name" value="RNA-bd_AU-1/RNase_E/G"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004659">
        <property type="entry name" value="RNase_E/G"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022967">
        <property type="entry name" value="S1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30001">
        <property type="entry name" value="PTHR30001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10150">
        <property type="entry name" value="RNase_E_G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00757">
        <property type="entry name" value="RNaseEG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="S1 motif" evidence="6">
        <location>
            <begin position="39"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC92817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="485" mass="54391" checksum="6F3213CD72F18E51" modified="2018-07-18" version="1">MSENILINITPQETRVALIFQGAVQELHIERTMSLGLVGNIYLGKVVRVLPGMQSAFIDIGLERAAFLHVADIWDSRANENATPTPIEKLLFDGQAITVQVIKDPIGTKGARLSTQISIAGRMLVFLPQDSHIGISQKIGNEAGREMLRTMVQNLLGPNEKGGFIVRTMAEDATEAELQMDVEYLRKTWASICMLAKSKPPTSLLHQDLNLAQRVLRDFVNIETDSIQIDSRENYQKLFEFAENYTPSVIPKLTHYTGERPLFDLYGVEEEIQRALGRRVDLKSGGYLIVDQTEAMTTIDVNTGSFVAGRNFADTIFKTNLEAAHAIARQLRLRNLGGMIILDLIDMDNQEHKTAVLTELNKAFARDRTKLSASGFSALGLVEVTRKRTRESLAHILCETCPACSGKGQVKTARTICYEILRELLREAKQFNPREFRILASQMVVDLFLEEESQHLAMLGDFIGKPISLQVESTYHQEHYDVILM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYM0</accession>
    <name>A0A2S9GYM0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acetyltransferase including N-acetylases of ribosomal protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2541</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92811">
        <property type="protein sequence ID" value="PRC92811"/>
        <property type="gene ID" value="S2091_2541"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="15"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="198" mass="22220" checksum="A37099C517B6F5C0" modified="2018-07-18" version="1">MNFLSCRKHIISDRLVLFRPTEDDLSAIYEIHADPATNLFNPKGPMQSISTAVELLAHWQSEWDDKGWGYWSIALRSEPERIIGFGGVSNRPRFGGSALVQRLNSQNAANLYFRFRPDTWGLGYANEMAQQALRLAFDEAGLDCVFGIARESNVASRRVLERLGLNFVELSEDESGVDSNAVYSIDARTFSTRLGRLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYV9</accession>
    <name>A0A2S9GYV9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2326</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92909">
        <property type="protein sequence ID" value="PRC92909"/>
        <property type="gene ID" value="S2091_2326"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="101" mass="11443" checksum="47965DC6479DB92A" modified="2018-07-18" version="1">MSKLIVQRHKAIWQDAARDYVILVDGKELGRVGNGSEIEIQIKPGTHTVQLKIDWCRSPKITITVATEQAITLDCGPNSTPLLALIYIIFLRKNYLWLRAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYW5</accession>
    <name>A0A2S9GYW5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Prolyl oligopeptidase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_2336</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92919">
        <property type="protein sequence ID" value="PRC92919"/>
        <property type="gene ID" value="S2091_2336"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011044">
        <property type="entry name" value="Quino_amine_DH_bsu"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50969">
        <property type="entry name" value="SSF50969"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015686736" evidence="2">
        <location>
            <begin position="28"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S9" evidence="3">
        <location>
            <begin position="419"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="633"/>
            <end position="658"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC92919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="658" mass="73849" checksum="70CFF8FC22E240A0" modified="2018-07-18" version="1">MAFLPLLKKFVHFIILFSLACAPVCVAALTFDDALSPAGIQAATLSPDGKHIAAIAFTGMNHGIILIDVDTNKAKLINSGKWTTRGNIRYSKEARKVFWIGNDLLAVDFGAYSETITLEGKSVTDIGDIVIGKLNTGQPDSPMLLVHDDFRDDDISIVNAKTGKMTGFSLPGFGTPDHWTFDKHGQLRAITMFNSAFWKDVTTVTNWYRPDTTKPWVKLDEFKVTDNYWFPVAVSDKENTLIISSNMGRDTRAIFSYDTVKHEIGEMMAGHPTQDILDVEGINLDSFTSVLTNGMMPQRFWFDPDWDQIQKTVDAALPKRINIISGDTANRILVFSYSDIDPGRWFILDIPTMKMHLVAEAKPKIDPDKMLPMEIISYPSKDGFVIPAYLTRPANAKGMQPTIVLIHGGPWVRDTWDWNMEVQLLADRGYAIFQPQFRGSYGFGLKFQEAGYQQWGKSMQDDITAGVDYLIKEGIADPKRICIYGASYGGYAALWGLVKTPDLYQCGISFAGVSDIGDMLEDSSDRNHNKITREVQRSRIGDIAMSKEQFAQVSPLKHADQIKAPLLLLHGEDDRRVPISHSKNMMQALDANHKVYEWVEFADEGHGLTYVKDSYRFYEALFKFLDKYNPPDPKPIIEHASEVKSPQPETDESSKPTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYZ6</accession>
    <name>A0A2S9GYZ6_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Antitoxin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2347</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Antitoxin component of a type II toxin-antitoxin (TA) system.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the phD/YefM antitoxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92930">
        <property type="protein sequence ID" value="PRC92930"/>
        <property type="gene ID" value="S2091_2347"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006442">
        <property type="entry name" value="Antitoxin_Phd/YefM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036165">
        <property type="entry name" value="YefM-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02604">
        <property type="entry name" value="PhdYeFM_antitox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143120">
        <property type="entry name" value="SSF143120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009981"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU362080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="81" mass="8788" checksum="050248ECABF3DD76" modified="2018-07-18" version="1">MQTVNIHEAKTHLSRLIEQAAKGESFIIAKAGKPLVKVMSLTSPESGQVKRLGFMSGQLRIPDDFNQMGSTEIEQLFGSGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZ58</accession>
    <name>A0A2S9GZ58_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2428</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC93011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93011">
        <property type="protein sequence ID" value="PRC93011"/>
        <property type="gene ID" value="S2091_2428"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018721">
        <property type="entry name" value="DUF2252"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39441">
        <property type="entry name" value="PTHR39441"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10009">
        <property type="entry name" value="DUF2252"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="408" mass="46165" checksum="51EBC3F80792D79F" modified="2018-07-18" version="1">MKKSQRQLLEPDQRLLFLRAQRNLKMARSVQSYVRGSTTKFYEWLETSSSGKFPEGPAIWICGDCHFGNLGPVANADGQVEVQIRDFDQTVIGNPIHDLIRLGLSLAIAARDSDLPGVITLKMLEQLMEGYAQEFHDETLTMPRPECVKLVMRQASTSKWKNFAKQNLDNLDPSIPLGKRFWPISQSESLAITKMFGDKEFSGLATRLRARNDDAVVTVLDAAYWRKGCSSLGNLRYAALLDIDQEVSKGRDFCLMDIKQAIKALAPRAFDAKMPRDNGKRVLEGALQLSPYLGERMLASQLMGCSVFIRELLPQDLKLEVNKLTQLEAMIAAKYLGSIVGKAHARQMDAGTRSKWCGELLRNQTKKFELPDWLWNSVVELIATHESSYLEHCRTYVMDTEFSEHKIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZB7</accession>
    <name>A0A2S9GZB7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2157</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93071">
        <property type="protein sequence ID" value="PRC93071"/>
        <property type="gene ID" value="S2091_2157"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="72" mass="7656" checksum="9733DF578D6EEB88" modified="2018-07-18" version="1">MKKIDATTLLGGTPTAAADAIGITYQAYSQWPDVLPLRLQDRVQAAIARKHLPPEVLGSKVVSTPASKNSRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZH3</accession>
    <name>A0A2S9GZH3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Mg-dependent DNase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2221</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93135">
        <property type="protein sequence ID" value="PRC93135"/>
        <property type="gene ID" value="S2091_2221"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01310">
        <property type="entry name" value="TatD_DNAse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018228">
        <property type="entry name" value="DNase_TatD-rel_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001130">
        <property type="entry name" value="TatD-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01026">
        <property type="entry name" value="TatD_DNase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005902">
        <property type="entry name" value="DNase_TatD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01091">
        <property type="entry name" value="TATD_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="265" mass="28895" checksum="540CF4A22FD8C839" modified="2018-07-18" version="1">MWIDTHCHLDAPEFNGTGAQVALRAKQRGVRSIVVPAVCRANFASVANLGQFGGYALGIHPIFVPKAEEADLQFLRTSVERAMSDPHFVAIGEIGLDFFVAELCTPEMREKQAYFYREQLRIAKDFGLPVLLHVRRSVDQILKYLRQIGVPGGIAHAFNGSQQQADMLIKLGFKLGFGGAMTYTRALQIRRLASTLPLSSIVLETDAPDIPPNWLEAGQNSPEQLPQIAEVLAQLRGISLDELASATCANASAVLPRLLALPPPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZI3</accession>
    <name>A0A2S9GZI3_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">Phosphate transport system permease protein PstA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_2112</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell inner membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93026">
        <property type="protein sequence ID" value="PRC93026"/>
        <property type="gene ID" value="S2091_2112"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005315">
        <property type="term" value="F:inorganic phosphate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035435">
        <property type="term" value="P:phosphate ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005672">
        <property type="entry name" value="Phosphate_PstA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00974">
        <property type="entry name" value="3a0107s02c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="33"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="81"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="122"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="153"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="207"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="268"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="8">
        <location>
            <begin position="85"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC93026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="298" mass="32235" checksum="9AAF052CF90349E3" modified="2018-07-18" version="1">MNAHSTLTTVETKSTPINNAVYQRRLWVHRIGISLSFLAMVIGVFFLLWILLTLFIKGFSSLNLSMLTESTPPPGSDGGGLLNAIVGSAMMVGVATVICTPIGILAGLYLAEYGEANWFAQLTRFVTDIMLSAPSIVIGLFVYALYVANMNHFSGWAGSIAISLIAIPVIVRTTDNMLQLVPGSLREAAFALGAPRWKVAILVRLRAVKAGVITGVLLAVARISGETAPLLFTALNNQFYNSDMNKPMANLPVVIYQFAMSPYENWRTLAWGGALIITLSVLGLNILSRTLFNQKIQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZJ8</accession>
    <name>A0A2S9GZJ8_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="8 13">Aspartate-semialdehyde dehydrogenase</fullName>
            <shortName evidence="13">ASA dehydrogenase</shortName>
            <shortName evidence="13">ASADH</shortName>
            <ecNumber evidence="8 13">1.2.1.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Aspartate-beta-semialdehyde dehydrogenase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">asd</name>
        <name evidence="15" type="ORF">S2091_2240</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 13">Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>L-aspartate 4-semialdehyde + NADP(+) + phosphate = 4-phospho-L-aspartate + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:24284"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57535"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:537519"/>
            <dbReference type="EC" id="1.2.1.11"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4 13">Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; (S)-tetrahydrodipicolinate from L-aspartate: step 2/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 13">Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-homoserine from L-aspartate: step 2/3.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5 13">Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 2/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7 13">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6 13">Belongs to the aspartate-semialdehyde dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.11" evidence="8 13"/>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93154">
        <property type="protein sequence ID" value="PRC93154"/>
        <property type="gene ID" value="S2091_2240"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00034">
        <property type="reaction ID" value="UER00016"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00050">
        <property type="reaction ID" value="UER00463"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00051">
        <property type="reaction ID" value="UER00464"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004073">
        <property type="term" value="F:aspartate-semialdehyde dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071266">
        <property type="term" value="P:'de novo' L-methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019877">
        <property type="term" value="P:diaminopimelate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009088">
        <property type="term" value="P:threonine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02121">
        <property type="entry name" value="ASADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000319">
        <property type="entry name" value="Asp-semialdehyde_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011534">
        <property type="entry name" value="Asp_ADH_gamma-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012080">
        <property type="entry name" value="Asp_semialdehyde_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000534">
        <property type="entry name" value="Semialdehyde_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012280">
        <property type="entry name" value="Semialdhyde_DH_dimer_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46278:SF4">
        <property type="entry name" value="PTHR46278:SF4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01118">
        <property type="entry name" value="Semialdhyde_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02774">
        <property type="entry name" value="Semialdhyde_dhC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00859">
        <property type="entry name" value="Semialdhyde_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01745">
        <property type="entry name" value="asd_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01103">
        <property type="entry name" value="ASD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="10 13" id="KW-0220">Diaminopimelate biosynthesis</keyword>
    <keyword evidence="11 13" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="12 13" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="13" id="KW-0521">NADP</keyword>
    <keyword evidence="13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 13" id="KW-0791">Threonine biosynthesis</keyword>
    <feature type="domain" description="Semialdhyde_dh" evidence="14">
        <location>
            <begin position="3"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-thioester intermediate" evidence="13">
        <location>
            <position position="135"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="13">
        <location>
            <position position="280"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="10"/>
            <end position="13"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="73"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="102"/>
        </location>
        <ligand>
            <name>phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="162"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="165"/>
            <end position="166"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="242"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="245"/>
        </location>
        <ligand>
            <name>phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="273"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="356"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00005097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00010584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00013120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="PRC93154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="374" mass="40545" checksum="2A57FAAA0B5CB9B6" modified="2018-07-18" version="1">MKLVGLVGWRGMVGSVLLQRMQEEGDFAHIEPVFFSTSNAGGKAPSMAKNETSLQDANDIAALKKCDIIITCQGGDYTSEIFPQLRASGWNGYWIDAASTLRMNDDAIIILDPVNSDVIKSGLSRGIKNYIGGNCTVSCMLMGLGGLFEHDMVEWVTSMTYQAASGGGAQHMRELLTQFGQINASVKSLLDNPSSAILEIDRQVLAQQHAFTAEDTKQFGVPLAGNLIPWIDKDLGDGSSKEEWKAGAETNKILGRGAGFNKTAIPVDGLCIRVGAMRCHSQALTIKLKQDVPLNELADIIAQNNQWVKVVENTREASMRELTPAAVTGSMTIPVGRLRKLQMGGDYLSAFTVGDQLLWGAAEPLRRMLRILVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZL0</accession>
    <name>A0A2S9GZL0_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Dihydropteroate synthase</fullName>
            <shortName evidence="1">DHPS</shortName>
            <ecNumber evidence="1">2.5.1.15</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Dihydropteroate pyrophosphorylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2233</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; tetrahydrofolate biosynthesis; 7,8-dihydrofolate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate and 4-aminobenzoate: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the DHPS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.15" evidence="1"/>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93147">
        <property type="protein sequence ID" value="PRC93147"/>
        <property type="gene ID" value="S2091_2233"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00077">
        <property type="reaction ID" value="UER00156"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004156">
        <property type="term" value="F:dihydropteroate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046656">
        <property type="term" value="P:folic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046654">
        <property type="term" value="P:tetrahydrofolate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00739">
        <property type="entry name" value="DHPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045031">
        <property type="entry name" value="DHP_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006390">
        <property type="entry name" value="DHP_synth_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011005">
        <property type="entry name" value="Dihydropteroate_synth-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000489">
        <property type="entry name" value="Pterin-binding_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20941">
        <property type="entry name" value="PTHR20941"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00809">
        <property type="entry name" value="Pterin_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51717">
        <property type="entry name" value="SSF51717"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01496">
        <property type="entry name" value="DHPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00792">
        <property type="entry name" value="DHPS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00793">
        <property type="entry name" value="DHPS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50972">
        <property type="entry name" value="PTERIN_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0289">Folate biosynthesis</keyword>
    <keyword evidence="1" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pterin-binding" evidence="2">
        <location>
            <begin position="21"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU361205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="288" mass="31788" checksum="B6ACC5D67CC0106C" modified="2018-07-18" version="1">MEKYLQCGRYRFPLIGKDARPLVMGILNVTPDSFSDGSENADLNFLLDRAEAMINAGVDIIDIGGESTRPGAKPVSLELELQRVMPIIYALRDCGIPLSIDTYKPEVMREAQLAGVDMINDVHGFRAEGALEAVANSDCALCIMHMQNTPQTMQDQPQYDDVITEVSDFFAERIRTMQQHRIEKNRLLLDVGFGFGKSLPHNLTLLRQQKLFSERFSLPVLAGLSRKSMLGALTGKPVELRLAASIGAAITAVAHGAQIVRVHDVAETIDALTIWNSIKNINQQGIEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZQ6</accession>
    <name>A0A2S9GZQ6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1957</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93219">
        <property type="protein sequence ID" value="PRC93219"/>
        <property type="gene ID" value="S2091_1957"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12802">
        <property type="entry name" value="MarR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00347">
        <property type="entry name" value="HTH_MARR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="1">
        <location>
            <begin position="25"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="138" mass="15321" checksum="72F4605B60D7E721" modified="2018-07-18" version="1">MDINVLELGRAIKQLQNLNHRRLEIGLREVDSTLAQWDALRAIDANPGVSAHALAEETFQTDQSFGTLATRLIAKELVERQQGMGRALIYSLTPKGQHVLEQGLVVAEQVIDDSFKNLSDSEQAQFLALTRKALLNNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZX3</accession>
    <name>A0A2S9GZX3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein involved in outer membrane biogenesis</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_2022</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93284">
        <property type="protein sequence ID" value="PRC93284"/>
        <property type="gene ID" value="S2091_2022"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007844">
        <property type="entry name" value="AsmA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05170">
        <property type="entry name" value="AsmA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="9"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="domain" description="AsmA" evidence="3">
        <location>
            <begin position="4"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="669"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="673"/>
            <end position="689"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC93284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="699" mass="75187" checksum="6B42F45F87CC8C6B" modified="2018-07-18" version="1">MPAKFLKILFYITAPLLLIVVISMTLLFTYDWNQARPFINRTVSSSIGRDFAVRGDLKIQLISGSQTESGWERYLTTLPILRISADDVQISNPSWSHVGAQMASARRVVVLLKPFALLSKEAIVTELDLDTPLVVLERRADGSNSWSLPDNGPSTWAVQIQRLAFADGNMRYVDYGINLDLHARATSVAGDALAAPDQTKNALTAQQFGLQFILGGTYHHAAISGSGKLGSVLTLENKSTVFPIQADMQIGANKIAFNGVITDPRAPSGINVELTLGGTSLAALYPLTGVLLPETAAYKTRGRLLGQKEHANWNWTYQNFIGTVGASDLAGTLQYVYRLPRPLLRGAVTSNQLRLDDLGPIIGADSNEHKIARGEAPIQPDGKALPVEQFHTAQWGALDADVKFSGKHLIRTHDIPLDNIVTDIHLENKVLSLAPLYFGLAGGDVTSNIVLDGRKPAIDAQIKMAARNLQLRELFPTLQSMKASFGEINGDAALTGHGNSVSAMLASSNGELVATMSQGSVSRYILEAAGLNVANVLFVKMFGDKQVRLNCLVSDFAVNAGVAGVRHFVIDTDDAIVNITGEVDLSRELLNLDVRPNTKGMRIFSLRSPLYAKGSFEHPDVGPYKGPLVLRATAAIALAALSPPAAALASVNLGTTPIIDCPAELNKALRTRSAPKSEPTASPAGRVSNKEIQKSREEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZZ0</accession>
    <name>A0A2S9GZZ0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2043</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93305">
        <property type="protein sequence ID" value="PRC93305"/>
        <property type="gene ID" value="S2091_2043"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="79"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="124" mass="12974" checksum="6A664EE17B37E355" modified="2018-07-18" version="1">MKTMARNSLIITITLTALAFIAVCLMYCFADPMTVIVDSEHVTGITGAGFAFGGVLMAIVAVVLCAVFVSLILAGVSVFLIALFAALFIGGLVLLSPLLFPALLVIGLIMLFHRKKPHHADAAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H051</accession>
    <name>A0A2S9H051_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HDIG: uncharacterized domain HDIG</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93362">
        <property type="protein sequence ID" value="PRC93362"/>
        <property type="gene ID" value="S2091_2100"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006675">
        <property type="entry name" value="HDIG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013976">
        <property type="entry name" value="HDOD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08668">
        <property type="entry name" value="HDOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00277">
        <property type="entry name" value="HDIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51833">
        <property type="entry name" value="HDOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HDOD" evidence="1">
        <location>
            <begin position="16"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="280" mass="31153" checksum="867B11F1AB637C6E" modified="2018-07-18" version="1">MKNIDPNEISNSVQKLPALSAIVVELLSSIDQENIDIDDIAKKISYDHVLTIKTLRLANSSFYGMQHKISSVHEAIVILGFRNVRMLIATSAITSSFSATELQNFSFPSFWRHSIGTAVCAKEIAAHIGSNQEYAFIAGLIHDIGKLVLATQYSGQYEKTLEYQELHNCDPLIAERETLGTDHSAIGTIVAKHWKFPEEMQLAVSQHHPEEGEQVVHLAGVIHLANIFALALDFSNDERAVVPKISPFVWDNIKLDEQACNQIFVSSAKKFEEIAQILIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H068</accession>
    <name>A0A2S9H068_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2086</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93348">
        <property type="protein sequence ID" value="PRC93348"/>
        <property type="gene ID" value="S2091_2086"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015531434" evidence="1">
        <location>
            <begin position="21"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="98" mass="10954" checksum="5E818E8E22FFC78D" modified="2018-07-18" version="1">MCIHQQLPFLLLFASTLCVASDGVIRFTGRIVEPTCIVQTETLPAPRLNACSVHVALSTSVDSVIITPESHMLVWRANDVTKQDLPVNHWKIIRVNYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H085</accession>
    <name>A0A2S9H085_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Phosphate transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_2014</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Membrane</location>
            <topology evidence="1 6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93276">
        <property type="protein sequence ID" value="PRC93276"/>
        <property type="gene ID" value="S2091_2014"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005315">
        <property type="term" value="F:inorganic phosphate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006817">
        <property type="term" value="P:phosphate ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001204">
        <property type="entry name" value="Phos_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11101">
        <property type="entry name" value="PTHR11101"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01384">
        <property type="entry name" value="PHO4"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0592">Phosphate transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="33"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="65"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="108"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="149"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="175"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="214"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="253"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="278"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="430"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="521"/>
            <end position="543"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC93276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="547" mass="57564" checksum="8A7805B6AC4B1F36" modified="2018-07-18" version="1">MDSSAQLNAAVPPHATSTIPSALSEHKTGPATLILFAVLLLLGLIYTAMSLTADVTEAGPTTTQWLPYFLLGLALLIALGFEFVNGFHDTANAVATVIYTHSLPPNFAVMWSGCFNFLGVLLSSGAVAFGIISLLPVELILQVGSGSGFAMVFALLIAAIIWNLGTWWLGLPASSSHTMIGSILGVGIANALMHGRTGTSGVDWAQATKVGYSLLLSPLVGFVCAALLLLAMRAFVKSKELYEAPVGNTPPPWWIRGLLILTCTGVSFAHGSNDGQKGMGLIMLILVGTVPMAYALNRAMPVDHVTQFVAVAHVTQISLDKYTAPLSLPPAASTAASRDTLITFIRTKELTPEALPALSTLTGAIGERVKESGSLANVPATNVTNVRNDMYLVAEAIRVLDKNPAVNFDADTKANLTAFKKQIDDATKFIPLWVKIAVAIALGLGTMVGWKRIVVTVGQKIGKTHLTYAQGASAELVAMLTIGAADVFGLPVSTTHVLSSGVAGSMAANRSGLQMSTIRNLAMAWVLTLPVAILLSGSLYWLFSHLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0U0</accession>
    <name>A0A2S9H0U0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">AcCoA-C-Actrans: acetyl-CoA C-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_1579</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the thiolase-like superfamily. Thiolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93578">
        <property type="protein sequence ID" value="PRC93578"/>
        <property type="gene ID" value="S2091_1579"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00751">
        <property type="entry name" value="thiolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002155">
        <property type="entry name" value="Thiolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020615">
        <property type="entry name" value="Thiolase_acyl_enz_int_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020617">
        <property type="entry name" value="Thiolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020613">
        <property type="entry name" value="Thiolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020616">
        <property type="entry name" value="Thiolase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02803">
        <property type="entry name" value="Thiolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00108">
        <property type="entry name" value="Thiolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000429">
        <property type="entry name" value="Ac-CoA_Ac_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01930">
        <property type="entry name" value="AcCoA-C-Actrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00098">
        <property type="entry name" value="THIOLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00737">
        <property type="entry name" value="THIOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thiolase_N" evidence="5">
        <location>
            <begin position="9"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="domain" description="Thiolase_C" evidence="6">
        <location>
            <begin position="275"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-thioester intermediate" evidence="3">
        <location>
            <position position="95"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="354"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000429-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC93578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="398" mass="41981" checksum="2948196981A5D00E" modified="2018-07-18" version="1">MTKQLQDAYIVAATRTPIGKSGRGMFKNTRPDDLLVRVLQSALAQVPNLDPKLIEDAIVGCSFPEAEQGSNLARMAVLLAGLPQTVGGVTINRFCASGITAVAMAADRIRVGQADVMIAAGAESMSMVPMMGHHPSINMGVFKDENIGMAYGMGLTAEKVAQQWKVSREDQDAFALQSHQRAIAAQNAGYFDAETTSVEIIERIPNFATGQIELKTRTVNRDEGARPDTSLEGLAKLKAVFAAKGTVTAGNSSQTSDGAGALILVSEKILKQFNLTPLARFASFAVRGVPPEIMGIGPKEAIPAACRAAGITQDQIDWFELNEAFAAQSLAVVRDLGLDPAKVNPMGGAIALGHPLGATGAIRSATAIHAMHRNNLKYSMVTMCVGTGMGAAGIFERM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H139</accession>
    <name>A0A2S9H139_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="18">Cytochrome c oxidase subunit 2</fullName>
            <ecNumber evidence="18">7.1.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="24" type="ORF">S2091_1703</name>
    </gene>
    <organism evidence="24 25">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="24 25" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="24 25">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15 18">Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="18">
            <text>4 Fe(II)-[cytochrome c] + 8 H(+)(in) + O2 = 4 Fe(III)-[cytochrome c] + 4 H(+)(out) + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:11436"/>
            <dbReference type="Rhea" id="RHEA-COMP:10350"/>
            <dbReference type="Rhea" id="RHEA-COMP:14399"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="EC" id="7.1.1.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="18">
            <name>Cu cation</name>
            <dbReference type="ChEBI" id="CHEBI:23378"/>
        </cofactor>
        <text evidence="18">Binds a copper A center.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="17">Cell membrane</location>
            <topology evidence="17">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 17">Belongs to the cytochrome c oxidase subunit 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="24">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.1.1.9" evidence="18"/>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93702">
        <property type="protein sequence ID" value="PRC93702"/>
        <property type="gene ID" value="S2091_1703"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070469">
        <property type="term" value="C:respirasome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004129">
        <property type="term" value="F:cytochrome-c oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045187">
        <property type="entry name" value="CcO_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002429">
        <property type="entry name" value="CcO_II-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001505">
        <property type="entry name" value="Copper_CuA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014222">
        <property type="entry name" value="Cyt_c_oxidase_su2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011759">
        <property type="entry name" value="Cyt_c_oxidase_su2_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036257">
        <property type="entry name" value="Cyt_c_oxidase_su2_TM_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22888">
        <property type="entry name" value="PTHR22888"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00116">
        <property type="entry name" value="COX2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02790">
        <property type="entry name" value="COX2_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13442">
        <property type="entry name" value="Cytochrome_CBB3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="SSF49503"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81464">
        <property type="entry name" value="SSF81464"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02866">
        <property type="entry name" value="CoxB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00078">
        <property type="entry name" value="COX2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50857">
        <property type="entry name" value="COX2_CUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50999">
        <property type="entry name" value="COX2_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13 18" id="KW-0186">Copper</keyword>
    <keyword evidence="10 17" id="KW-0249">Electron transport</keyword>
    <keyword evidence="5 16" id="KW-0349">Heme</keyword>
    <keyword evidence="12 16" id="KW-0408">Iron</keyword>
    <keyword evidence="14 19" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 16 18" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="25" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 17" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="20" id="KW-0732">Signal</keyword>
    <keyword evidence="9" id="KW-1278">Translocase</keyword>
    <keyword evidence="7 17 19" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 19" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 17" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="20">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015485167" description="Cytochrome c oxidase subunit 2" evidence="20">
        <location>
            <begin position="26"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="63"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="105"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="domain" description="COX2_TM" evidence="22">
        <location>
            <begin position="38"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="domain" description="COX2_CUA" evidence="21">
        <location>
            <begin position="134"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="23">
        <location>
            <begin position="299"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00024688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU000456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="RuleBase" id="RU004024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS50857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="PROSITE" id="PS50999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="EMBL" id="PRC93702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="396" mass="43705" checksum="5234F7CC80A3C07E" modified="2018-07-18" version="1">MKYAKRLPSLMLGSLMMMAGVSSWAQQVVDKVVDSKGGPAVRGMNFQPPVTQIAEQIYNLHTLMMIICMVIFLIVFGVMFYSILKHRKSLGHKPATFHESITVEIAWTIVPFIIVIAMALPATKTVVAMKDTSNSDITIKATGMQWKWGYDYLKGEGEGISFLSNLSTPREQIGGPGKPPTQARGENYLIEVDNEVVVPVNKKIRIITTANDVIHSWTIPAFGIKQDAIPGFVRDTWFKAEKIGKYRGQCVELCGKEHAFMPVVVNVVSEADYTKWVDGKKKEMAALADDPNKVWTVDELKQRGEKVYSANCIVCHQANGKGVPGAFPALDGSPIVAGPKEAQMHIVMNGKNAMPTWKNVLSDTDIAAVITFTRNNWSNKAQENIVQPAEILAARK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H194</accession>
    <name>A0A2S9H194_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1714</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93713">
        <property type="protein sequence ID" value="PRC93713"/>
        <property type="gene ID" value="S2091_1714"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07377">
        <property type="entry name" value="WHTH_GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00392">
        <property type="entry name" value="GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50949">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="2">
        <location>
            <begin position="19"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="481" mass="53883" checksum="8A4D6C5834F736C8" modified="2018-07-18" version="1">MAKPHILQFSLMLNRASPVRLVEQVVLAMTQLIEQGRLRSGERLPSVRQFAVEQKMGISTVVEAYEQLVARGLLVVRRGAGFFVAFQGNVAQSMPTFKVSKPVIDSAWLLSEVFADERVPNKAGCGWLPSKWLDHDGLHQAERRLMRAPGAQQVGYGHPHGYLPLRLVIAQFLANWSLEVAPEQILTTHGATQALDIIIRTMTQRGDTVLIDEPGYCNLMAMLKLADLNVIGVPRTPGGIDVEQLDRLARLHQPKLFFTASVLQNPTGTSYTPACAMKVLQAAERHHFWVVEDDIFRELGQATDPMLAALDGLQRVIYVGGYSKTIAPSLRLGYIVCQRELARQLVHTKMVQSLTNSEITERLVHSVLTEGHHRRHVEQLALTLLDAGTRVNARLTESGLKPFAIARGGLFCWAKFEHSTLNAREIADRALQQGIWLAPGDFFHFTAPQHPWFRFNVAYADVNELVEFFTLLAKNDVRRQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1B7</accession>
    <name>A0A2S9H1B7_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">4-hydroxythreonine-4-phosphate dehydrogenase</fullName>
            <ecNumber evidence="4">1.1.1.262</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">4-(phosphohydroxy)-L-threonine dehydrogenase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">pdxA</name>
        <name evidence="5" type="ORF">S2091_1367</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>4-(phosphooxy)-L-threonine + NAD(+) = 3-amino-2-oxopropyl phosphate + CO2 + NADH</text>
            <dbReference type="Rhea" id="RHEA:32275"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57279"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58452"/>
            <dbReference type="EC" id="1.1.1.262"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <cofactor evidence="4">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="4">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
        <text evidence="4">Binds 1 divalent metal cation per subunit. Can use ions such as Zn(2+), Mg(2+) or Co(2+).</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Cofactor biosynthesis; pyridoxine 5'-phosphate biosynthesis; pyridoxine 5'-phosphate from D-erythrose 4-phosphate: step 4/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="4">The active site is located at the dimer interface.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the PdxA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.262" evidence="4"/>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93758">
        <property type="protein sequence ID" value="PRC93758"/>
        <property type="gene ID" value="S2091_1367"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00244">
        <property type="reaction ID" value="UER00312"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050570">
        <property type="term" value="F:4-hydroxythreonine-4-phosphate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050897">
        <property type="term" value="F:cobalt ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042823">
        <property type="term" value="P:pyridoxal phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008615">
        <property type="term" value="P:pyridoxine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00536">
        <property type="entry name" value="PdxA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037510">
        <property type="entry name" value="PdxA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005255">
        <property type="entry name" value="PdxA_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30004">
        <property type="entry name" value="PTHR30004"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04166">
        <property type="entry name" value="PdxA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00557">
        <property type="entry name" value="pdxA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0170">Cobalt</keyword>
    <keyword evidence="1 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0520">NAD</keyword>
    <keyword evidence="4" id="KW-0521">NADP</keyword>
    <keyword evidence="3 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-0664">Pyridoxine biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="binding site" evidence="4">
        <location>
            <position position="138"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="139"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="175"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="220"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="275"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="283"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="292"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="301"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC93758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="343" mass="36571" checksum="1BF85632037022B5" modified="2018-07-18" version="1">MIPTLAITVGEPAGIGPEISLRAAWQKRSECHSVLIGDIDFLRVLARQIDPAMVLDSIADLSQISKRNSHTDTALTVLHSPLAVSVIPGTLDARNGLAVLATLDLAIAGAMQGQFDAIVTAPLQKSTINDAGMPFSGHTEYLAEQTHIKKVVMMLACSKTHTQNRALRVALATTHLPLRAVADAINFNELTQIIDIIHADLQSKFGIQQPVILVAGLNPHAGENGYLGCEEIDIIAPAIVAAQARQIDVRGPYPADTLFQEKYLEQADCVLAMYHDQGLPVLKYASFGMGVNITLGLPMIRTSVDHGTALDLAARGVGHADLGSMLEAIDVAVAMTKTKSITK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1C8</accession>
    <name>A0A2S9H1C8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">IPT/TIG domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1376</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93767">
        <property type="protein sequence ID" value="PRC93767"/>
        <property type="gene ID" value="S2091_1376"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005546">
        <property type="entry name" value="Autotransporte_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036709">
        <property type="entry name" value="Autotransporte_beta_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003343">
        <property type="entry name" value="Big_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008964">
        <property type="entry name" value="Invasin/intimin_cell_adhesion"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002909">
        <property type="entry name" value="IPT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02368">
        <property type="entry name" value="Big_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01833">
        <property type="entry name" value="TIG"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="SMART" id="SM00869">
        <property type="entry name" value="Autotransporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00635">
        <property type="entry name" value="BID_2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00429">
        <property type="entry name" value="IPT"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103515">
        <property type="entry name" value="SSF103515"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49373">
        <property type="entry name" value="SSF49373"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="SSF81296"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51208">
        <property type="entry name" value="AUTOTRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Autotransporter" evidence="1">
        <location>
            <begin position="1964"/>
            <end position="2243"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="2243" mass="219453" checksum="61ECF880A273A0CC" modified="2018-07-18" version="1">MQSFEKSIQAIQQCNALLKQFIGYFLHFFVFNSKKQTPRQKSTSNGIGFFGILFSKRLALLFAIACSQLFFSSSASASSCAPTFTVAENSSTYTYTLATNVAGADYSCDPNGTFGIYDDTVCDTGTIATSQGGTALMDGGSPDTIQYTPAAGFSGTDIVTFYNTNNGAVCVAQHATVTVTPSGPSVTSLATTAGPIAGGTSVIITGAGFSSVTAVNFGGTAATSYTVNSTTQITATAPAHSAGVVDVTVTATGGTSATGAGDHYTYAGLPTVTSLSPSSGVVAGGTSVVITGTNFSAATAVKFGATNATSYTVNSATQITATAPAGSAGTVDVTVVTVGGTSATVAGDHYTFVAAPTVTGLSPTSGTAAGSTSVTITGTNFTGATAVQFGGTNATSYTVNSATQITATAPAHSAGTVDVTVITTGGTSATGASDHYTFVAAPTVTGLSPTSGTAAGGTSVTITGTNFTGATAVQFGGTNATSYTVNSATQITATAPAGSSGTVDVTVVTTGGTSATGASDQFTYVSAPVVSSISPGSGPLAGGTSVVITGTNFTGATAVQFGGTNATSYTVNSATQITATAPAGSAGTVDVTVVTTGGTSATGASDHFTYVSAPVVSSISPGSGPVAGGTSVVITGTNFTGATAVQFGGTNATSYTVNSATQITATAPAGSAGTVDVTVVTTGGTSATGAGDHYTYVSTPTVTSLSPGSGVAAGGTSVIITGTNFTGASAVKFGVTNATSYTVNSATQITATAPAGSAGTVDVTVVTSGGTSATGVSDQYTYVSAPTVTSLSPGSGTAAGGTSVVITGTNFSGASAVMFGVTNATSYIVNSATQITATTPAGSAGTVDVTVVTTGGTSATGASDHYTFVAGPTVSGLSPTSGATSGGTSVIITGTNFSGASAVKFGVTNATSYTVNSATQITATAPAGSAGTVDVTVVTTGGTSATGAGDHYTYVSTPTVTSLSPGSGVAAGGTSVIITGTNFTGASAVKFGVTNATSYTVNSATQITATAPAGSAGTVDVTVVTSGGTSATGVSDQYTYVAVATVTGISPGSGAAAGGTSVIITGTNFSGASAVKFGTNNATSYTVNSATQITATSSAGTGTVDVTVVTTGGTSATSVSDQYTYVAAPTVTGLSPNSGLVAGGTSVVVTGTNFSGASAVKFGTSNATSYTVNSATQITATAPSGTGTVNVTVITTGGTSATGVSNQFTYVPIGVLTFTTPTSASVTLGGSLTNAASSTLTGGSYGAITYSSSNTAVATVNSSGVITTVSAGTSTITATQAAVTNVNAQATQTYTLTVNTLPVGTVSFTTPTSASVTLGGSLTNAASSTLTGGSYGAITYSSSNTAVATVSGSGVITPVSAGTSTITATQAAVAGVNAQATRTYLLTVNTLPVGTLSFTTPSSAAVTLGGSLTNAATSTLTGGSYGAITYSSSNTAVAAVGSSGAITPISAGTSTITATQAAVAGVNGVATRTYTLTVNTLPVGTLSFTTPTSASVKVGGSLTNAATSTLSGGSYGAITYSSSNPSVATVNSSGVVTGIGVGTVTITVTQAAVAGVNAQVTQSYTLTVNALSVGVLSFATPSSASVMMGASLTNVATSTLAGGSYGAITYSSSNTAIATVSSSGVVTPVSAGTCTITATQAAVVGMNVVASNTYQLSVNKKVQTTLVVSSSASTIVKGTGTVVLTVTGGSGAGAVSYAVTTGSCTLSGTTLTASATAGTCVVTVTKVADANYAAATATVTVTVQNIASSSVILASSNPAPQQGQTVTLTAAITPASATGTVHFMDGNTMIGTGTVTAGVANYATNTLTMAAHSLVAHYSGDSATAASVSAPLMLTIIGRPNPTLNPAVKANVAAHAAATQRFTMAQMTNIYSHVQLLHNDFSVGNNFNLGMNASHLDMLNLVGNEIINNYTGTYPNDQTNTGLASGSMMTRAPYAGDSGMHNTSAAGDGVDENAERKNNNALHFAGMPIGFWSAGNVDYGSLNSQDGSTNTFSSSGLTIGVDMLVHSNLIVGASLGYARDTTTTDSFGSDSKSRQLSASLYGSYQPMSHWYIDVVAGYGQLNYDNQRWSPDENMMFAGNRDGRVYYASASLAKDILFDRIHLQPFGRFDVLNAHLNSYSEQGGNDMALTYQSSTFTSTAFTGGLTLFRDWAVDAGILTPSLKFQLSHLASGDVNQGMYYSDLGSSSTNYNVIVTGMPENTQSIGFGLNLKTRDGIQANCGWLGSLGSSSYHDNSFKIDVRIGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1D6</accession>
    <name>A0A2S9H1D6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative CDP-diglyceride synthetase/phosphatidate cytidylyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1677</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93676">
        <property type="protein sequence ID" value="PRC93676"/>
        <property type="gene ID" value="S2091_1677"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="76"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="100"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="124"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="194"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="218"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="268"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="288" mass="32143" checksum="7AAF64A765D740A9" modified="2018-07-18" version="1">MLILYSILGISSAVIAIKTRALTVSQLRQQVFAWWRIFPIVTLSLFFYPLGPLLLMLFICGLSMRELATHFSGAQHIFWLACGLVLVCAVFLWIDHSAHFVVFFPCLLILQLLFFMRRRDPNQLVLLLFLFCCYCVGFVINLMHLPLSDDTGLAWLFYLFALTALNDIAQFVSGKLFGCHAIASRISPNKTWEGLIGGVLISMLVSVLLGRYLNLADIPFLLLLALLLSLGGFAGDLLFSAAKRFLGIKDFSQLIPGHGGILDRIDSLTITAPLLYLAIYFSLNGFLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1I0</accession>
    <name>A0A2S9H1I0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Zinc carboxypeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1419</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93810">
        <property type="protein sequence ID" value="PRC93810"/>
        <property type="gene ID" value="S2091_1419"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004181">
        <property type="term" value="F:metallocarboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000834">
        <property type="entry name" value="Peptidase_M14"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00246">
        <property type="entry name" value="Peptidase_M14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_M14" evidence="1">
        <location>
            <begin position="25"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00246"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="562" mass="64402" checksum="B0D8B0123AB38C7F" modified="2018-07-18" version="1">MLPELLTTYEKGNKNQTTTWEECIAFYQHLSGRFPAILQFFQIGVSDGGVPLYAGLVSADGVFDLEQIKREGRPVFFNNNGIHPGEPEGIDVCMALVRDFCIEPERLAALGRTVFLFVPVYNVDGSWNRNSSSRVNQDGPELFGFRANSLNLDLNRDFIKCDSLNAQAFNQLFTTWNPDVMVDTHTSNGADYSYTMTLIQTQADKLGGELGGFLRNTMVPEIYKNMEQRGWPTCPYVNPVTEIPDDGIEDFLEVPRFSTGYAALHHTIGFMPETHMLKPYADRYESMRALVEVALNFTVKHAEQIQTLRAEAKRAAAHKTQWPVSWKVDRSKPSTFRFKGYAAVYSPSLLGNYTRLAYDRSQPWEKDIAYYDNFVEDVVVNVPKAYVIPQAWRAVIQRLRWNGVQLDRLTDTKTCSVQTYHIKAVTSRATPYEGHMFHDEVELEERTEQVILRAGDYLVSLNQPNARYVVETLEPQAHDSFFRWGFFNSVLEKKEAFSNYVFEDTALELLNAEPGLKAQFEQWKSENPALLSDQNAVLSFIFAHCKRFNEPEWKRYPVLRLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1P8</accession>
    <name>A0A2S9H1P8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1524</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93915">
        <property type="protein sequence ID" value="PRC93915"/>
        <property type="gene ID" value="S2091_1524"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="101"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="193"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="287"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="194"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="314" mass="33781" checksum="34D856A4BBAF4332" modified="2018-07-18" version="1">MTTVNSALRPDLELISSSNRQVDAENQKDAWLRQLELSQMSLLQQLGQQNSGSSGNNNGSAVSKDSHDGQSESQPNSSFGGSSETTSATLLPVHPILNQHSTTTDEASHSPTQSNQTVKSNEVSHSSIQTTKPEQETIGQITQNQLDVSNQQGNLSAPIISEQLGSTLTQQISITTPTTVNNLAVIAMRVSNESTSMEKEEASESSEQQKTEPSETHDAASNNVWQKRLMHVAQEGKNVSVSIRDNTLDAHQSSQIVTRLAGDAAQSGLRLRNATVNGKTLLKLPRTTTALPNSPSNDVDITTHSFTSSLEIQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2A9</accession>
    <name>A0A2S9H2A9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">GGDEF: diguanylate cyclase (GGDEF) domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_1256</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94083">
        <property type="protein sequence ID" value="PRC94083"/>
        <property type="gene ID" value="S2091_1256"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013656">
        <property type="entry name" value="PAS_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08448">
        <property type="entry name" value="PAS_4"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="27"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="80"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="103"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="137"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="178"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="443"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="2">
        <location>
            <begin position="483"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="2">
        <location>
            <begin position="607"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="3">
        <location>
            <begin position="762"/>
            <end position="895"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC94083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="898" mass="100368" checksum="752B127B30A645FE" modified="2018-07-18" version="1">MVFNTGLCFALAGVALALPEIMQLPPSNLQTVMGAFLIGLCCITLLEITLDKNFGIDLVALHTWLNYDNVRPGRMAPNSALGFICAGLVLVLMNHVNSKWQAIAVQVLTYVVLVIGLTGLVGYYLNQDLLFGWARSARMSINTAIGMIVTAGALRFSWHHADWYRSQKYLREDQKITLASAAIIIVVIITAGLTSFVVLQQTLEATLNQSLRTKLSERKVLFRTIINAGINKAQVIAQNYLVTQRFIESSRNDQLKQELAEEARKILGSQFTGVTLFDPLGKQIFAGGQNRSADNIQIKLNTQTSATLFWDDGFFLKTEFPIEIQTRQIGKIVLEQKMDEFEHQMFNIDGLGASAEIAICTAVKTKIQCFPNTVKSTPFMVEPVGAAGHPLPMAYALQSETGFVQALDYRQKNVAAFFSPLSNNLGIVVKEDTAELYAGIRDALVSCSLIICILSGFGIVLLRFQLHPLTSRLFSSENKLRKSEKRLKAIADNIPAIIAHLDVEERYLFINAQTSKTFDAGDIDIIGHTIKEIRDPELYAHLQPYIRMVLSGQRVTFESSLNLNGKPTHLQSSYVPDIDADDNVVGFYAMTFDITIPKNNELRQRELEQQLRTITDNLPVLITYIDKELNFKFCNRTMFKWMGIEPQDIINHPVTDLFGITFFEQARAQMDRALRGERVEFSSELTVRNVTRLLQTTYIPEQISDGSIVGIYTLSSDVTDSKIIENKLTMLARVDSLTGLPNRLQLNEKLNEAINRKKRSKKAMAVMFIDIDHFKSINDTMGHAAGDAVLREFGRRLKAAVRTTDTVARMAGDEFVIIIEEIQTVEEAKLIAEKIIEQANQIWQIGAQQLSVTTSIGVAFNLDEDLNSDELLAIADKALYRTKANGRNGYFILPPVVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2J5</accession>
    <name>A0A2S9H2J5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">LTXXQ motif family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_1350</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CpxP/Spy family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94177">
        <property type="protein sequence ID" value="PRC94177"/>
        <property type="gene ID" value="S2091_1350"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012899">
        <property type="entry name" value="LTXXQ"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07813">
        <property type="entry name" value="LTXXQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0574">Periplasm</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015616591" evidence="6">
        <location>
            <begin position="31"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="149"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC94177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="168" mass="18904" checksum="6FE9395151D9830B" modified="2018-07-18" version="1">MKKIGKHLGKKIAFGFIAFGFVAASALVNAQEHVSRACQDQTKMVESVQANMVKHQTQLHEQLKLTEAQEPAWKNFVASMPAPAKPTRLDRAAMEKLTTPERMEQQLNMLKEHEAKMTANLLALKTFYAALTPEQQKTFDDYHSKMGRNAHHKADLKVDTKVEAKSDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2K6</accession>
    <name>A0A2S9H2K6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acetyltransferase (GNAT) family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0819</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94198">
        <property type="protein sequence ID" value="PRC94198"/>
        <property type="gene ID" value="S2091_0819"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="11"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="210" mass="23274" checksum="B7FC19C6AA0084EE" modified="2018-07-18" version="1">MNNPPSNHRTVLVKELSARHRSRVSHHFSSLDQHDRILRFGTHLSNESISNYVKGINFELDKVFGVFSYSFRLVGVGHLAFVPRADRPLVDGVIQKVAEFGVSVSSNARGLGIGSKLFERAAIHCRNANVTTLYMHCLSSNQTMMHIAKKAGMEIHRDYGEADAYLTVLPADPGSVIQEAMQEQVASLDYSLKANTSSVLNFLGFGKKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2Q9</accession>
    <name>A0A2S9H2Q9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0890</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94269">
        <property type="protein sequence ID" value="PRC94269"/>
        <property type="gene ID" value="S2091_0890"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="44" mass="5493" checksum="99A0DDD03803CC10" modified="2018-07-18" version="1">MFYFNNPNQLKMFLMSKHLIHRLLYVAQYKDFARYYMLITLSMP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H354</accession>
    <name>A0A2S9H354_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1036</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94415">
        <property type="protein sequence ID" value="PRC94415"/>
        <property type="gene ID" value="S2091_1036"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="58" mass="6507" checksum="A8FFEFBBEEA18C25" modified="2018-07-18" version="1">MGLMMNVSANSDVMIAGVEVEIVPYLRVRATDELKKSIHREIKNQIKLGPLMSVYFAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3D1</accession>
    <name>A0A2S9H3D1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DprA: DNA protecting protein DprA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1102</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DprA/Smf family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94481">
        <property type="protein sequence ID" value="PRC94481"/>
        <property type="gene ID" value="S2091_1102"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009294">
        <property type="term" value="P:DNA-mediated transformation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003488">
        <property type="entry name" value="DprA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041614">
        <property type="entry name" value="DprA_WH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43022">
        <property type="entry name" value="PTHR43022"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02481">
        <property type="entry name" value="DNA_processg_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17782">
        <property type="entry name" value="DprA_WH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00732">
        <property type="entry name" value="dprA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DprA_WH" evidence="2">
        <location>
            <begin position="317"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="376" mass="40061" checksum="AD556FA691BC3481" modified="2018-07-18" version="1">MSDVSDWIRLTATPGIGCEAARKLLLEFGLPDQIFSASYAALKQVVSERQAKALCEPPTETILALIERTHLWCAEPNNFLITLADNNYPTLLLEIPDPPTLLYVKGRIELLSNTSIAVVGSRNASTQGSINAKQFSSNLSQSGLTIVSGMALGIDTAAHEGGLESLDLTSGSTIAVIGTGADIVYPARNRGLAHKIAEHGCIVSEYALGTPAIASNFPRRNRLISGLSQGVLVIEAAAQSGSLITARMALEQGRDVFAIPGSIHSPLAKGCHLLIKQGAKLVETAQDILQELRLDTLDSKPEPAQSMLPFPSNTNNEIETEAESELLIAIGYDPIHPDVLAQRCNVDSGELSAKLLMLELDGHVEVLAGGLYRRLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3J4</accession>
    <name>A0A2S9H3J4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1057</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94436">
        <property type="protein sequence ID" value="PRC94436"/>
        <property type="gene ID" value="S2091_1057"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07377">
        <property type="entry name" value="WHTH_GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00392">
        <property type="entry name" value="GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50949">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="2">
        <location>
            <begin position="22"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="498" mass="55462" checksum="F0A1F6EC693952AC" modified="2018-07-18" version="1">MTKSFELETLKIRMNETDFQSLGIHQRIQRGLRDLILDGALRAGLKLPSSRTLAVSLRVARDTVENSYEQLHRDGFIVRRKGSGSYVSKTFGAQLRGLSDSRLKPEVSKCNVKNASNGLSRRGRNIFDGGGVSDQQLIKAFATGLPETRNFPIDVWERLQRQTMKEFRSNALLHGDPQGAKPLRRTIAAYLNLERGAKVCAEQIVVLSSTRQSLFLCAQLLVDAGKSILFENPGYFGAKKAFEFAETSIVPIEVDAQGIRTDLLLTDRSSANCIYVTPSHQYPTGVTMSLERRLELISWAAKNDKWIIEDDYDSEFHYDGLPIACVQGLDKYHRTIYLGTFSKTLYPGLRIGYIALPQELVKAFTNARSIIDGHTPQILQLTLARFMEDGHYNSHVRSMRKLYAGRRKIMLDAISKHLAGIVTPLLTEGGLQIPCLLAHGWSEAKTICQAAAAGVELSGLSRLYAGENKKEGWILGYASLTAIEIDVAMRRLAKALRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3P8</accession>
    <name>A0A2S9H3P8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0601</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94598">
        <property type="protein sequence ID" value="PRC94598"/>
        <property type="gene ID" value="S2091_0601"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="36" mass="3942" checksum="C6101DFD4418F494" modified="2018-07-18" version="1">MEGLTRKVRLAAALAEFITRPQADLKSAQGIRITKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3V6</accession>
    <name>A0A2S9H3V6_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Aminopeptidase</fullName>
            <ecNumber evidence="8">3.4.11.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">S2091_0644</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Release of an N-terminal amino acid, Xaa-|-Yaa- from a peptide, amide or arylamide. Xaa is preferably Ala, but may be most amino acids including Pro (slow action). When a terminal hydrophobic residue is followed by a prolyl residue, the two may be released as an intact Xaa-Pro dipeptide.</text>
            <dbReference type="EC" id="3.4.11.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="8">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the peptidase M1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.-" evidence="8"/>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94641">
        <property type="protein sequence ID" value="PRC94641"/>
        <property type="gene ID" value="S2091_0644"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09601">
        <property type="entry name" value="M1_APN-Q_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1730">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045357">
        <property type="entry name" value="Aminopeptidase_N-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042097">
        <property type="entry name" value="Aminopeptidase_N-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024571">
        <property type="entry name" value="ERAP1-like_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034016">
        <property type="entry name" value="M1_APN-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001930">
        <property type="entry name" value="Peptidase_M1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014782">
        <property type="entry name" value="Peptidase_M1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027268">
        <property type="entry name" value="Peptidase_M4/M1_CTD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11838">
        <property type="entry name" value="ERAP1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01433">
        <property type="entry name" value="Peptidase_M1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17900">
        <property type="entry name" value="Peptidase_M1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00756">
        <property type="entry name" value="ALADIPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63737">
        <property type="entry name" value="SSF63737"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 13" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="5 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 8" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="3 8" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <keyword evidence="6 8" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015741087" description="Aminopeptidase" evidence="9">
        <location>
            <begin position="24"/>
            <end position="884"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M1_N" evidence="12">
        <location>
            <begin position="45"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M1" evidence="10">
        <location>
            <begin position="264"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="domain" description="ERAP1_C" evidence="11">
        <location>
            <begin position="555"/>
            <end position="862"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU364040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF11838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF17900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PRC94641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="884" mass="96005" checksum="6FEFBD7CC32BC411" modified="2018-07-18" version="1">MHRHLISAAVLALVGFSCAPVFANSAVTSTPQTQTTTQLPRTVSPTHYALSLTPNAAAATFSANIKISINVLKPTSSITLNASDLAFQQVLLSSAHGKAALKASKISVNAEEETATFHFAHPIAKGSYTLDIAYTGVIGTQANGLFSVDYDTAAGHKRAIYTQFENSDARRLIPSWDEPAYKATFALEVTVPSTQMAVSNMPITSKTDLPDGRSVINFGMTPKMSTYLLFFGLGDFERATDSIDGTEVGVITQKGSLSQAAFPLAASKAILHEYNDYFGVRFPLPKLDNVAAPGSSQFFSAMENWGAIFTFEHGMLLDPSISTQGDKEVSFIIVAHEMAHQWFGDLVTMRWWDDLWLNEGFASWMENRMTERLHPEWNTKLGVVDVHESAMGLDSLSTTHPIVQRIDTVEQASQAFDEITYSKGESVIHMLEGYVGSDAWRDGVRIYMKAHAYSNTTSDDFWHSIEKATNKPISEIAHDFTLQPGIPMIKMGEVSCANGTTSVNLTQAEFSRDHLDKKSLTWHVPVTAQVLGAAPAQTLVADGKGTIQLAGCGPVLINAGQTGYFRTLYTPTQFAALAANFATITPIDQLGLMSDAWSLGLAGLQPMSDFLDLANVTPLTADPQIWNRIANTYSSIHQAYQADPLRQQQFDKFAIARLTPVMAKISWNAHADDTSAIINLRQQLISTLSQLNDPATINEANRRYAAPASDPTAFPVELRKVIMSVIALHADAATWEKLHAAAQTEKSAMMKDQLFYLIATSKDPALATRALEIAISDEPGATNSAGMISVVAHLHPDLAFDFAIAHLAQVEKLVDASSRSRYLPRVASGSAEPAMVDKLNAYANAHLTPSALGSTKTAIASINYHIKVRSQRLPAIDAWLAAHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3X3</accession>
    <name>A0A2S9H3X3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative extracellular repeat, HAF family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0682</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94679">
        <property type="protein sequence ID" value="PRC94679"/>
        <property type="gene ID" value="S2091_0682"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014262">
        <property type="entry name" value="Extracellular_HAF"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02913">
        <property type="entry name" value="HAF_rpt"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015556397" evidence="2">
        <location>
            <begin position="21"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="338"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="380" mass="40092" checksum="29835C4B57D341F0" modified="2018-07-18" version="1">MHRNLQSCIFLLVLFGGEAAATTTTHSLGIVPPAKGGSIAYDMNAAGQVAAVIQDESGGQRGVFFENGKLIELGTLGGKDSEAKRINDKGEIIGSASKKDGAWSAVLYNQASGMHELGTLGGTNSYGTALNNEGSAVGFSDIASGDWHAFLYKNGEQLKDLGTLGGKISYASGINNMGQVVGTATLPDEHRHAFFYEPARGMIDLGTLGGRSSSATAINDKGVIVGASETADHHWHAFVYDGQRMVDLGAIIGRGDSFATSINSAGHVVGTVRIGEDCMSFVWRDNKVTLHYCGKGLFLTNAINDTEQVVGATYDHGLNAATMLSNTAPFVDHGHVKFINQIVLVLLLAGAAVIYRKRYRGILLDGSADLGVGKNRFLPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H460</accession>
    <name>A0A2S9H460_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0744</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94741">
        <property type="protein sequence ID" value="PRC94741"/>
        <property type="gene ID" value="S2091_0744"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="78" mass="8603" checksum="54AB8783283727AC" modified="2018-07-18" version="1">MLGGPPPIGFKITGTYNKAKNVIEIIAYDGNEKGPLGTLVFDEKSNTLVENPSGNSPYHRRFNEIPDDAKSTLLRLRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H465</accession>
    <name>A0A2S9H465_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cytochrome c</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_0770</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94767">
        <property type="protein sequence ID" value="PRC94767"/>
        <property type="gene ID" value="S2091_0770"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008168">
        <property type="entry name" value="Cyt_C_IC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00034">
        <property type="entry name" value="Cytochrom_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13442">
        <property type="entry name" value="Cytochrome_CBB3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00605">
        <property type="entry name" value="CYTCHROMECIC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0349">Heme</keyword>
    <keyword evidence="3 4" id="KW-0408">Iron</keyword>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015528589" evidence="5">
        <location>
            <begin position="24"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="6">
        <location>
            <begin position="32"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="6">
        <location>
            <begin position="129"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC94767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="217" mass="22932" checksum="EA47655BC89E590B" modified="2018-07-18" version="1">MNQKSFLNSILIAMLAFSTLAYAAEEKTLVKADPVKGEALYTNGDATRNIIACVSCHGAAGNSTISQNPKLAGQHAAYLAKQLGNFTEPSRNNAVMTMTAKALSPEDIKNVTAYLSTQVTKSGAAKNSDLVEKGKKIYRSGIASINVPACAGCHGPNGSGIPALFPRLAAQHQDYTVAQLTNFRSGARTNSPEMIAISHRMSDEEIKAVADYVAGLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4G8</accession>
    <name>A0A2S9H4G8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_0053</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94858">
        <property type="protein sequence ID" value="PRC94858"/>
        <property type="gene ID" value="S2091_0053"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.550">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023352">
        <property type="entry name" value="MAPEG-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001129">
        <property type="entry name" value="Membr-assoc_MAPEG"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01124">
        <property type="entry name" value="MAPEG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161084">
        <property type="entry name" value="SSF161084"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="63"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="101"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC94858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="131" mass="14456" checksum="03D1DC51A1AB4DAE" modified="2018-07-18" version="1">MTNALALVVYMAIVTWLTLLIASMMRARGWTLPGIILALGNRENMPEPLAVADRADRAARNTLENFVLFAALVLTAHAMGVVDHRIELGAEIFFWARLAYIPIYIAGIIYVRTVVWTISIIGLGMITSTLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4J9</accession>
    <name>A0A2S9H4J9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Biopolymer transport protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_0105</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Membrane</location>
            <topology evidence="1 6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the exbB/tolQ family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94910">
        <property type="protein sequence ID" value="PRC94910"/>
        <property type="gene ID" value="S2091_0105"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002898">
        <property type="entry name" value="MotA_ExbB_proton_chnl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01618">
        <property type="entry name" value="MotA_ExbB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="14"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="121"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="165"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="domain" description="MotA_ExbB" evidence="8">
        <location>
            <begin position="81"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC94910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="216" mass="23881" checksum="572B8E0E0ADEE552" modified="2018-07-18" version="1">MIKNEFTFVTNREFALFAILQSAGWPIYFLLIASIIALALIIERSLSLRSQRILPRTLLDEVVRVYHNGKVSKDVVEKLEQNSPLGRVLAAGLRNVDAPREVMKEAIEEAGRAAAHELERFLTTLGTIASLATLMGLFGTVVGMIEIFGAQNATGANPAQLAHGISVALYNTAFGILIAMPTFFFYRHFMALVDGFVIDMEQQAVKFVDIVHSNRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4K0</accession>
    <name>A0A2S9H4K0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Hsp70 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_0068</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the heat shock protein 70 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94873">
        <property type="protein sequence ID" value="PRC94873"/>
        <property type="gene ID" value="S2091_0068"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd10231">
        <property type="entry name" value="YegD_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018181">
        <property type="entry name" value="Heat_shock_70_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042054">
        <property type="entry name" value="YegD-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19375">
        <property type="entry name" value="PTHR19375"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00329">
        <property type="entry name" value="HSP70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC94873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="417" mass="45109" checksum="A88AE7358E10568B" modified="2018-07-18" version="1">MVSACGLDFGTSNSTVGWCQHGKATLLALEEGKLTLPSVVFFNVEDDSVSFGRAALAEYLAGYEGRMMRSLKSLLGSNLIDGQTEVGGKIITFRLLLAQFIKELKRRAELAAGHQFSNVVMGRPVYFVDGNADADRLAEKTLSEIASAAGFKNVVFQYEPIAAAFDYEATIQKEELVLIVDIGGGTSDFSLVRLSPDRAAKNDRRDDILATGGVHIGGTDFDKYFSLSSVMPLFGLGTQLRNNTEVPSSYYFNLATWHTINLAYTKKVQAQLADVAQHAKEPEKLGRLLNLVEQRAGHWLALKVEEAKIALSDAESVELALDRLSPQQNLSLNRQQFDDSIAHLISKIETTVTGMLNDAGVSADAVDTVFFTGGSSGVHLLREKIAAMVPSARRVEGDLFGSIGSGLAIDAARLFGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4P0</accession>
    <name>A0A2S9H4P0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ABC-type antimicrobial peptide transport system ATPase component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_0150</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94955">
        <property type="protein sequence ID" value="PRC94955"/>
        <property type="gene ID" value="S2091_0150"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03255">
        <property type="entry name" value="ABC_MJ0796_LolCDE_FtsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017911">
        <property type="entry name" value="MacB_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-1278">Translocase</keyword>
    <feature type="domain" description="ABC transporter" evidence="7">
        <location>
            <begin position="2"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="38"/>
            <end position="45"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC94955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="227" mass="24646" checksum="4478FDA0DE647B99" modified="2018-07-18" version="1">MIKLNNLSKVYSTGEVRTTALNGINLEIDAGEYVAITGPSGCGKSTLLGLLGLLDIPDSGDYWFDGKNVANWSEAKLNQLRRGRIGFIFQSFNLIEELSVFENVELALEYGDVPARERRDRVAAILEKLGISHRAKHRPSQLSGGQQQRVAIARALVSGPAMLLADEPTGNLDSAHGDEVMRLLRKINSEGTTIVMVTHSPMHAAQASRTLHMLDGNILIDAQMAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4S3</accession>
    <name>A0A2S9H4S3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Zn-dependent oligopeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">S2091_0177</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="7">Binds 1 zinc ion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the peptidase M3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94982">
        <property type="protein sequence ID" value="PRC94982"/>
        <property type="gene ID" value="S2091_0177"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06456">
        <property type="entry name" value="M3A_DCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1370.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034005">
        <property type="entry name" value="M3A_DCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024077">
        <property type="entry name" value="Neurolysin/TOP_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045090">
        <property type="entry name" value="Pept_M3A_M3B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001567">
        <property type="entry name" value="Pept_M3A_M3B_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43660">
        <property type="entry name" value="PTHR43660"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01432">
        <property type="entry name" value="Peptidase_M3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 7" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2 7" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="5 7" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015393703" evidence="8">
        <location>
            <begin position="24"/>
            <end position="710"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M3" evidence="9">
        <location>
            <begin position="255"/>
            <end position="708"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC94982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="710" mass="79812" checksum="186FADE4D235B22D" modified="2018-07-18" version="1">MIRLRMMVLATTMAFAASSPVLAAETLASNPFYNSSALPFNAPQFDKIQDTDYQPAIEEGMRLQLLEIQQIANNPEAPTFENTYVAMEKSGAMLTRVLQVFGAITGANTDDALQKVQEDEAPKLAAHQDAIYLNDKLFKRVEAVYKQVGKLKLDAESKRLVDVVYRNFVHAGAKLSAADKTKLKALNEEESTLSTQFGNKLREATKNAALVLDDKAQLAGLSDAAIAAAAATAKERGLDGKYVLSLQNTTQQPELQELTNRATRKALFEASWNRAEKGDANDTRKLLVRIAQIRAAQAKLIGFKNYAAWKLDDQMAKTPATAIKFMEQLVPAATARAKHEAQDIQAQIDKDQAELKQPTFKLEPWDWNFYAEQVRKARFDLDENQIKPYFELNSVLQNGVFYAANQLYGLTFTERHDIPVYQADVRVFEVFDKDGKSLALFYCDYFKRDNKNGGAWMDNFVGQSKLFGTKPVIYNVTNFTKPVAGQPALLSFDDVITMFHEFGHGLHGIFADEQYPTLSGTSTARDFVEFPSQFNEHWATDPKVFANYAKNYQTGELMPQAMVDKLKKAASFNKGYNMTELSAAALLDLNWHTLNANAPLQDANKFEAAALKKEKIDLSEVPSRYRTSYFLHIWGNGYAAGYYAYPWTQMLADDGFEWFKENGGLTRANGDRFRAMVLSRGNTEELSKMYQDWRGRAPSIEPMLENRGLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4W9</accession>
    <name>A0A2S9H4W9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Response regulator of the LytR/AlgR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_0230</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95035">
        <property type="protein sequence ID" value="PRC95035"/>
        <property type="gene ID" value="S2091_0230"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007492">
        <property type="entry name" value="LytTR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04397">
        <property type="entry name" value="LytTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00850">
        <property type="entry name" value="LytTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50930">
        <property type="entry name" value="HTH_LYTTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="2"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="domain" description="HTH LytTR-type" evidence="3">
        <location>
            <begin position="135"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC95035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="239" mass="27198" checksum="E84A24BE76106DAE" modified="2018-07-18" version="1">MNILIVDDELLARRLTREYLSKHTDMQIIGECENGLEAVQAISELAPDLIFLDIQMPKMSGLEVLEVTGRQSGVIFTTAFDEYALKAFDLHAVDYLLKPFSQQRFDAALNQARQLIGQKSANLINLITKSQLDRIVIRDRGQLHFISVSKIDYIEAQDDYIMIHSEGKSILKTQPLSDIEAQLDAKQFVRIHRSYLINIVNLNRIERINKDSLSAVLNNGTQIPISRAGYERIRLLVDC</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H540</accession>
    <name>A0A2S9H540_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 2">Adenylyl-sulfate kinase</fullName>
            <ecNumber evidence="1 2">2.7.1.25</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">APS kinase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">ATP adenosine-5'-phosphosulfate 3'-phosphotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Adenosine-5'-phosphosulfate kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">cysC</name>
        <name evidence="3" type="ORF">S2091_0283</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 2">Catalyzes the synthesis of activated sulfate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 2">
            <text>adenosine 5'-phosphosulfate + ATP = 3'-phosphoadenylyl sulfate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24152"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58243"/>
            <dbReference type="ChEBI" id="CHEBI:58339"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.25"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 2">Sulfur metabolism; hydrogen sulfide biosynthesis; sulfite from sulfate: step 2/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the APS kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.25" evidence="1 2"/>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95088">
        <property type="protein sequence ID" value="PRC95088"/>
        <property type="gene ID" value="S2091_0283"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00140">
        <property type="reaction ID" value="UER00205"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004020">
        <property type="term" value="F:adenylylsulfate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070814">
        <property type="term" value="P:hydrogen sulfide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000103">
        <property type="term" value="P:sulfate assimilation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02027">
        <property type="entry name" value="APSK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00065">
        <property type="entry name" value="Adenylyl_sulf_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002891">
        <property type="entry name" value="APS_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00455">
        <property type="entry name" value="apsK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 2 3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1 2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0808">Transferase</keyword>
    <feature type="active site" description="Phosphoserine intermediate" evidence="1">
        <location>
            <position position="109"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="35"/>
            <end position="42"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU004347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC95088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="203" mass="22187" checksum="C53F6CA20A7484D2" modified="2018-07-18" version="1">MVMQTSLISQHVGDVSPAKRHALLRQTPITLWLTGLSASGKSTLAFALEQELINQGRACYVLDGDNVRHGLSRNLGFSPEDRAENIRRVAEVAKLMNDAGLIVITALISPFRSDRAIAREIIGSDYMREVYVSTPLNVCESRDPKGLYSQARAGKITGFTGISSPYETPVQPDLTIDTTQYSLEMAIAQLVSVTLHQTLRSVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H589</accession>
    <name>A0A2S9H589_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative exporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_0344</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95149">
        <property type="protein sequence ID" value="PRC95149"/>
        <property type="gene ID" value="S2091_0344"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004869">
        <property type="entry name" value="MMPL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000731">
        <property type="entry name" value="SSD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03176">
        <property type="entry name" value="MMPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50156">
        <property type="entry name" value="SSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="253"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="279"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="306"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="348"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="374"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="426"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="645"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="670"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="696"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="727"/>
            <end position="747"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="753"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="domain" description="SSD" evidence="7">
        <location>
            <begin position="253"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC95149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="782" mass="86302" checksum="EE38493A37A8465C" modified="2018-07-18" version="1">MSRRNSIALCWALVVCLLLGHNAYLWLGKRIVPDTDIMALLPVQKRDPVLQQSFTHMVDAAQQRVIVLLGAKDWTDAKRAADAYSAVLSTKAELLTTTQLTDQTQNDWLAKFQEHSLILLSSEQESQLKTQSPQFWLDSALRNLYSPFSGPKLGAWRDDPFGLFTGWVQERAQETPVRPRDGYLFVANAERQYVLLSLTLKDSVFAMGVQQSVMALLKQANEAAHKTAPDAEIITAGVILHAAAAGEQASNEVFTIGLGSMLGIILLMWVTFHSLKPILLILLSIAIGCLGSLSICWILFERIHLLTLVFGASLIGVAQDYGIYFLCNRLSADAKLSSEALLKRLLPSLSLTLLAAVIGYMGLAFTPFPGLRYMAVFSALGLVFAWLTVICWFPLLISGGTLKSGALVRAYGNTLTRWPRLKANKITIFIGLIFVLFAAFGVARLGVNDDIRLLQNPPQHLIADQIKLSKLLDAPTPVQFYLVRGATQEIVLQREEALKKQLDPLIVQHKITGYQALSNWVPSAQTQSVRKALLEEKLLNEGGALTQLAQQLGEDADWVAATRTHLLNSGKLLTLDEFLKTPASEPWRHLWLGKVTDDYASIVALRGLSNVNLPLIQHAGDGLDGVQWVDKVAEISSVLGQYRHYMGWVVMCSYLVVFGLLFVRYRRDTWRVIAPAAIASIATLAILGFFNQHLQLFHVLPLMLLLGIGVDYGIFMQEKASVHHATAWLAIGLSAANTLLSFGLLGLSKTPALQSFGLTMLIGIALVWLIVPFFRKENLHGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5C5</accession>
    <name>A0A2S9H5C5_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glucokinase</fullName>
            <ecNumber evidence="1">2.7.1.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Glucose kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">glk</name>
        <name evidence="3" type="ORF">S2091_0377</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + D-glucose = ADP + D-glucose 6-phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17825"/>
            <dbReference type="ChEBI" id="CHEBI:4167"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61548"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.2"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the bacterial glucokinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.2" evidence="1"/>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95182">
        <property type="protein sequence ID" value="PRC95182"/>
        <property type="gene ID" value="S2091_0377"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004340">
        <property type="term" value="F:glucokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005536">
        <property type="term" value="F:glucose binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00524">
        <property type="entry name" value="Glucokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003836">
        <property type="entry name" value="Glucokinase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02685">
        <property type="entry name" value="Glucokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00749">
        <property type="entry name" value="glk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="1 3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="8"/>
            <end position="13"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU004046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC95182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="324" mass="34803" checksum="1F99851175A7CEF3" modified="2018-07-18" version="1">MTYPHLLADIGGTNARFAVETAPGKLEAILILPCANYATLSDAIKSYLATPLAIEAGASQVRKVGIAIANPVHGDLIQMTNHHWSFSIQSVKNEFNFSTLLVINDFKALAMALPFLDQTQKYQVGAGRAQEGGVIGLLGAGTGLGVSGLIPSKSGWVALDSEGGHTSFAPTNAREIAILQFALQTYKHVSSERLMSGAGLQLIYRALADLHKVTADDIDPPEIMRRGLENECPICSEVLTTFCELLGTMASNLAITLGSKGGIYIGGGIVPRLGSYFNQSHFRQRFEQKGRFANYLEQIPTFVITEPYPAFIGISAMLGQISQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5E8</accession>
    <name>A0A2S9H5E8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative N6-adenine-specific DNA methylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_0291</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95096">
        <property type="protein sequence ID" value="PRC95096"/>
        <property type="gene ID" value="S2091_0291"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034470">
        <property type="term" value="P:ncRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001510">
        <property type="term" value="P:RNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000241">
        <property type="entry name" value="RNA_methylase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004114">
        <property type="entry name" value="THUMP_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02926">
        <property type="entry name" value="THUMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01170">
        <property type="entry name" value="UPF0020"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00981">
        <property type="entry name" value="THUMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51165">
        <property type="entry name" value="THUMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="1 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="THUMP" evidence="3">
        <location>
            <begin position="52"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC95096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="405" mass="45459" checksum="D6A97F54DDF7454A" modified="2018-07-18" version="1">MTHRNSYFCPCPRGMEQALTEELAEITAQYCPTLHVHNQVPGGVHCSGELTDAYQINLHSRIASRVLLRMAHKSYTNENDIYDLTMEQPWEDWFSIHHTIRVDVTAIKSPLRSLEFTTLKIKDAVCDRFRDLCNERPSVDTQTPDIRLVGFLDARNFTLYIDTSGEPLFKRGWRMETGDAPLRENLAAGLLRVAGWKPGMTLFDPMCGSGTILAEAAQMLAGIPPGLHREFAFEKFGNFDAPSWQAIKASIKVNEVTGPATIFGSDISGDMVVMTRNNLNKAGIRFEVPLKQIEAQQIQAPPSEVAGIMLTNPPYGERIGVRGDSTIETDELANAFFSSFGTTLKQRFAGWQVFLFTADLTLPKMLRLKEARKTPFFNGALECRLFRFDMVAGFNRREAAKPKEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5K1</accession>
    <name>A0A2S9H5K1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0460</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95265">
        <property type="protein sequence ID" value="PRC95265"/>
        <property type="gene ID" value="S2091_0460"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015462519" evidence="1">
        <location>
            <begin position="32"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC95265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="110" mass="11606" checksum="66F4B00C7F79E9E9" modified="2018-07-18" version="1">MKTLNLTQANVQSKLILAVALIAAVAATSLAFQNGGGAKNTAIAMTEVPVQQVVIAGKRMTAEEKLAYDLAPKEIARVEIIGQRLSADEKVAMLAEDEINAKHAAAHRKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5N0</accession>
    <name>A0A2S9H5N0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0453</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95258">
        <property type="protein sequence ID" value="PRC95258"/>
        <property type="gene ID" value="S2091_0453"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015467478" evidence="1">
        <location>
            <begin position="23"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC95258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="182" mass="20532" checksum="B20D958971A08F20" modified="2018-07-18" version="1">MKFSPTAICITVLLHCVLYLSATTNFFHHDARKSPYVIVSVALPITTPNILRPHEENTPDLSELIATPESLINTEDTEPPIDEDRYYLPQELSQPVHVLQDDTAGLTTPIRQVVVMALYINEGGTVDDVVIERKGLLTDEEEGELKSAFKTLIFLPGMRGEKVVKALYRIQLEINRKIIIHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5S5</accession>
    <name>A0A2S9H5S5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC-type Fe3+ transport system permease component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_0478</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95283">
        <property type="protein sequence ID" value="PRC95283"/>
        <property type="gene ID" value="S2091_0478"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="29"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="61"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="104"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="167"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="201"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="259"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="299"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="335"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="373"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="427"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="481"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="25"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="300"/>
            <end position="499"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC95283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="506" mass="56037" checksum="27C6B659D1902D18" modified="2018-07-18" version="1">MLFSVFTPETEIWAHLQTYVLPELISNTLWLVLGVVAGTALLGVALAWLTAVCEFPGRTFFSWALMLPLAIPAYVAAFVAIGLFDFTGPLQTMLRDLTGGRSAWFPPIRSLGGAILILSLSLYPYVYLLARQAFLTQGSRALEAGQSLGLTRRMGFFRIALPMARPWIAAGLMLVVMETLADFGAVSIFNVDTFSTAIYKTWFGLFSLSAASQLASLLLLAILILVFAEQYWQRQRRYHSNSPDNSASKRIQLSPQARWYACAFAAVIFASGFVIPVTQLLAWSSKSLTGEWDQRFAGFVWHTVLLSSMAAGMVVLAALVLVITLRRHHDWPTRFFVRLATLGYAIPGTVLAVGIFIPAAWLDQQFFDISGHMLLRGSLALMLCAYLARFLAPAFNTLDSAMQRITKNQEDAARGLGLTGWRLFSRLYFPMLRGGILGAALLVFVDVMKEMPITLMTRPFGWDTLAVRIFEMTSEGQWEHAALPALAIVVIGLLPVFLLIRPKEFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GS74</accession>
    <name>A0A2S9GS74_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4719</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000053">
        <property type="protein sequence ID" value="PRC90572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90572">
        <property type="protein sequence ID" value="PRC90572"/>
        <property type="gene ID" value="S2091_4719"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC90572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="119" mass="12543" checksum="DDA6F48A31C64678" modified="2018-07-18" version="1">MGNGGTNTQYSYGSTSNQLTQVSGSQVNTIQSDANGSITNNVNNQFAYDARGRMVSAQTAIGSVQYKINALGQRVLKVTPTGTTVFNYDQGGKLIGESTGTKGADYIYLNDIPVAVAQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GS92</accession>
    <name>A0A2S9GS92_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">TonB C terminal</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4724</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000055">
        <property type="protein sequence ID" value="PRC90565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90565">
        <property type="protein sequence ID" value="PRC90565"/>
        <property type="gene ID" value="S2091_4724"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015438475" evidence="1">
        <location>
            <begin position="19"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="185" mass="20226" checksum="DA61525D3F60CD7F" modified="2018-07-18" version="1">MKRTVLFAAVFIFCNADAVVTTIGDKNYLVSVQGTNNSGSGVEQMVAATKEAVEFCKSRSGHFQLIKSNRLEPTSEQPPSARLEFSCISDAQLINIQYVKKVIGTIKKNVDYVPPNNQPLENATLEIKINLLPDGSSNGDPQVIKTSGNTNFDEAVKRGISHSFPFPADEYGHVPASLTIRYSLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSG1</accession>
    <name>A0A2S9GSG1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="8">CDF: cation diffusion facilitator family transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_4612</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000039">
        <property type="protein sequence ID" value="PRC90662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90662">
        <property type="protein sequence ID" value="PRC90662"/>
        <property type="gene ID" value="S2091_4612"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1510.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002524">
        <property type="entry name" value="Cation_efflux"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027470">
        <property type="entry name" value="Cation_efflux_CTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036837">
        <property type="entry name" value="Cation_efflux_CTD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027469">
        <property type="entry name" value="Cation_efflux_TMD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01545">
        <property type="entry name" value="Cation_efflux"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16916">
        <property type="entry name" value="ZT_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160240">
        <property type="entry name" value="SSF160240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161111">
        <property type="entry name" value="SSF161111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01297">
        <property type="entry name" value="CDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="26"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="93"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="126"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="domain" description="ZT_dimer" evidence="7">
        <location>
            <begin position="224"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF16916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC90662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="308" mass="33425" checksum="5E5DBBD6AB2FDE95" modified="2018-07-18" version="1">MAVHNHHTIEQPETPERHAAAKRSTLVSVLVNMVLGTVQIMIGIFSGSQGLIADGIHSLSDLMADFVVLVANQKSKKAADDDHQYGHLRYENAASLVLGMLLLAVGVGMLWSAVLKIQSPEHIPEVHVIALWVALGALVAKEGLFRYMLAIAQRIRSSMLIANAWHARSDAASSLVVALGICGNLMGYPLLDPIAALVVGLMVGRMGWKFAWDALHDLMDRAVSPEEANAIRTTLQETSGVLGLHDLRTRKVGDLIIVDVHLELDANLTVMEGHRIATDASDRVMRQHPVLNVMTHVDPVLNGVLIND</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSQ4</accession>
    <name>A0A2S9GSQ4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000036">
        <property type="protein sequence ID" value="PRC90752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90752">
        <property type="protein sequence ID" value="PRC90752"/>
        <property type="gene ID" value="S2091_4500"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC90752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="210" mass="23858" checksum="227A4FA3507D0180" modified="2018-07-18" version="1">MVHSRSEIVFRDASGMQHPFVPVKPQEAKSILAYNQIKFDLLEASEAFKKIQFYNEKNPDDASTMRHLFSSGIALYGRCITTSESRGIHLNPQQIQKLGNEQYEIYKEMEVLRHSHVAHAGKGRNATTVMILLNPIGKPKVIVGVKALDMNFDPTNKSIALKFSDHCLKLIEIVDRCISLAEKSLLKIYEKQNIEDLYRHAKGSFIVEQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSV5</accession>
    <name>A0A2S9GSV5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4462</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000035">
        <property type="protein sequence ID" value="PRC90799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90799">
        <property type="protein sequence ID" value="PRC90799"/>
        <property type="gene ID" value="S2091_4462"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC90799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="100" mass="11319" checksum="3E8217A6B947676C" modified="2018-07-18" version="1">MTSTDQSQTQKQAQFITSHAIDTVDAYTLAHDIVSDLSAIFELLEKLDFADYSNERLSRILSEAGFRHAADRLQLIDEKIIDAKKTLDELIDANKSNMKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSX1</accession>
    <name>A0A2S9GSX1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cytochrome c2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_4473</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000035">
        <property type="protein sequence ID" value="PRC90810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90810">
        <property type="protein sequence ID" value="PRC90810"/>
        <property type="gene ID" value="S2091_4473"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002327">
        <property type="entry name" value="Cyt_c_1A/1B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11961">
        <property type="entry name" value="PTHR11961"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00034">
        <property type="entry name" value="Cytochrom_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00604">
        <property type="entry name" value="CYTCHRMECIAB"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 5" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5" id="KW-0408">Iron</keyword>
    <keyword evidence="3 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015467474" evidence="6">
        <location>
            <begin position="24"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="7">
        <location>
            <begin position="25"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC90810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="125" mass="13698" checksum="B7E9BC14BCEBC614" modified="2018-07-18" version="1">MAPYQYLSGMALFFWGVASTVCAAGNAERGLALYQSKCVACHSIDYNGVGPAHKGLFNRKAGSQTDYVYSPAVKGSTIIWNEQTLDKWLSNPEKLIPGQKMGFSVPSAKERADLITYLKITTEQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSX9</accession>
    <name>A0A2S9GSX9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">FHA domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_4495</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000035">
        <property type="protein sequence ID" value="PRC90832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90832">
        <property type="protein sequence ID" value="PRC90832"/>
        <property type="gene ID" value="S2091_4495"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00060">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00240">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SSF49879"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FHA" evidence="2">
        <location>
            <begin position="149"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC90832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="231" mass="24331" checksum="E49217396A48AA5A" modified="2018-07-18" version="1">MQASPASAPASKSGGASNSSAVTANSVEKCPECMTLRPAGARFCEACRYDFVSRSSFSSLAAAAQTTSAQVPVAVAPSLDCAAPDTAQVLASTSTVADSVAAAANTFVSAQRLLLRVIVDPLLYTDPDPDLPCPTDRPEKIFHLDLNENTLGRQFEGNGVHPEIVVHDPSISRRHLKFVRGKNGEYSVLELGSANGTEFNSKTLEPGVVTALNPGDQITLGMWTRISVEAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSZ7</accession>
    <name>A0A2S9GSZ7_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">FGE-sulfatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4421</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000034">
        <property type="protein sequence ID" value="PRC90840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90840">
        <property type="protein sequence ID" value="PRC90840"/>
        <property type="gene ID" value="S2091_4421"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005532">
        <property type="entry name" value="SUMF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042095">
        <property type="entry name" value="SUMF_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03781">
        <property type="entry name" value="FGE-sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="SSF56436"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FGE-sulfatase" evidence="1">
        <location>
            <begin position="59"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="281" mass="31061" checksum="23B9BDCA9B1C3969" modified="2018-07-18" version="1">MKSENRLIFFTILLSTLIYLPSLSFGEQTITERTNSTSSLIKTITALGATFRDCDDGSCPEMVIIPRGTFMMGADPDSENGLRNEGPVHRVIIGAAFAIGKTTITQGQWKALMGSNPSGFINCGDTCPVENVSWYDAQDYINKLNQKTGKQYRLPSEAEWEYACRSGVRQEYCGSDNADSVAWHSGNSGGSPHPVATKQPNRWGVYDMSGNVSEWVEDCFNTYNAPADGTTRIDKQCKFGRVIRGGEWSGIPEQTRSASRAGLQETYRFVFDGFRVVRTLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GT21</accession>
    <name>A0A2S9GT21_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Thioredoxin reductase</fullName>
            <ecNumber evidence="3">1.8.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_4432</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>[thioredoxin]-dithiol + NADP(+) = [thioredoxin]-disulfide + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:20345"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.8.1.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="4">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.8.1.9" evidence="3"/>
    <dbReference type="EMBL" id="PUGF01000034">
        <property type="protein sequence ID" value="PRC90851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90851">
        <property type="protein sequence ID" value="PRC90851"/>
        <property type="gene ID" value="S2091_4432"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004791">
        <property type="term" value="F:thioredoxin-disulfide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019430">
        <property type="term" value="P:removal of superoxide radicals"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008255">
        <property type="entry name" value="Pyr_nucl-diS_OxRdtase_2_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005982">
        <property type="entry name" value="Thioredox_Rdtase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01292">
        <property type="entry name" value="TRX_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00573">
        <property type="entry name" value="PYRIDINE_REDOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2 3" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyr_redox_2" evidence="5">
        <location>
            <begin position="8"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC90851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="315" mass="33556" checksum="D42033FF3A566728" modified="2018-07-18" version="1">MSSTKHAKVLILGSGPAGYSAAVYAARANLNPVLITGVEQGGQLMTTTDVENWPADPMGVQGPELMQRFQQHAERFNTDIIFDYIHTVKLTEKPMRLIGDQSEYTCDALIIATGASAQYLGLPSEQAFMGKGVSACATCDGFFYKGKEVAVVGGGNTAVEEALYLSNIASKVTLVHRRDKFRAEAILVDRLLAKVAEGKIEIKYNHTLEEVTGDASGVTGINIKSAQDGTVQAIPLHGVFIAIGHKPNTSIFEGQLDMHNGYIQTKTGLEGMATATSIPGVFAAGDVQDHIYRQAITSAGTGCMAALDALRYLEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GT72</accession>
    <name>A0A2S9GT72_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glutathione S-transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_4410</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GST superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000033">
        <property type="protein sequence ID" value="PRC90917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90917">
        <property type="protein sequence ID" value="PRC90917"/>
        <property type="gene ID" value="S2091_4410"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00043">
        <property type="entry name" value="GST_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02798">
        <property type="entry name" value="GST_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="SSF47616"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GST N-terminal" evidence="2">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="3">
        <location>
            <begin position="87"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC90917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="215" mass="24208" checksum="CE2055F02207D68C" modified="2018-07-18" version="1">MSYTLYYSPGTASMAVHWMLIELGVAFETRLVDFESGQQRSPEYLRLNPAGRVPTLVIDGVPYSESTALLMLLAERHPAAALSPAPGTAERCEWMELMVYLANTVLPAMRDWFYADTDGDPIGADTIRNLARSRIEAACERLDKKLADGRTYIVGGKLSTADFLAVMLMRWTRNMPRPAMTWEHIELYVKRLRSLPSFITLNTNEGLTDWQNTAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTH2</accession>
    <name>A0A2S9GTH2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Helix-turn-helix domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_4284</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000031">
        <property type="protein sequence ID" value="PRC90988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90988">
        <property type="protein sequence ID" value="PRC90988"/>
        <property type="gene ID" value="S2091_4284"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="2">
        <location>
            <begin position="8"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="138"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC90988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="166" mass="18091" checksum="569099B62A562318" modified="2018-07-18" version="1">MIDFNVRLRAERKRLGLNQEKFAVLGGVTKDTQLNYESGSRKPDSDYLAAIARAGVDVLYLLTGELAVSALTQEENEVLIGYRSLDTRGKAGVLGLIDGMAPIEKTKKEELKKENLEIPVTPISGGNHFYGKVGEMTDVKGDQYNSGSKTINVGGDKKKKKSTPES</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTN1</accession>
    <name>A0A2S9GTN1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Multidrug resistance efflux pump</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_4258</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000030">
        <property type="protein sequence ID" value="PRC91070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91070">
        <property type="protein sequence ID" value="PRC91070"/>
        <property type="gene ID" value="S2091_4258"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043602">
        <property type="entry name" value="CusB_dom_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00529">
        <property type="entry name" value="CusB_dom_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="102"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="domain" description="CusB_dom_1" evidence="5">
        <location>
            <begin position="117"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="domain" description="HlyD_D23" evidence="6">
        <location>
            <begin position="140"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="280"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="46"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="73"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC91070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="441" mass="48456" checksum="FDDDDEA5C0FC8BE9" modified="2018-07-18" version="1">MHEDEHELDLNDDSNRNNESRPSVKEINDLALVNKKRHGRRATDPVYSVLSQQPVEANAETGMDSENGSKIQATPVKKEKTEDAGKPEDEDKKDDAKPRSKTPLIILAIVILILAIIAFIWWFDTRNQISTDDAYTDGNAVVMAPIVSGYVSSLLVNDNAFVHKGDVLVEIDSRDYAAVRDDAAAQVGLAQAQLESSKIALEMAKVQYPMQLAQAQAQENSALANLKKAQFTYDRQHAVDRRATTDENIDSANSAQAIAKANVDSANAQLKIAALVRQQLLQSQNKVTISQEQLRQAKAKLAATELNVAYCKIIAPSDGWITKRNVQLGSFLAAGTPMFILVNTDIWVTANFKESQLERMHVGDEVNMTVDAYPNRQLHGHVDSIQLGSGSRFAAFPTENATGNFVKIVQRVPVKIVIDRGLDPHQPLSLGLSISPVVLFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTV7</accession>
    <name>A0A2S9GTV7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NADH:flavin oxidoreductase / NADH oxidase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_4192</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000029">
        <property type="protein sequence ID" value="PRC91096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91096">
        <property type="protein sequence ID" value="PRC91096"/>
        <property type="gene ID" value="S2091_4192"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001155">
        <property type="entry name" value="OxRdtase_FMN_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00724">
        <property type="entry name" value="Oxidored_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Oxidored_FMN" evidence="2">
        <location>
            <begin position="30"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="domain" description="Pyr_redox_2" evidence="3">
        <location>
            <begin position="399"/>
            <end position="665"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC91096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="706" mass="76490" checksum="B1EFDA8469561665" modified="2018-07-18" version="1">MQRGVYPQLLPHVYSHLTAIAMTTSSHPHLLAPLDLGFTTLKNRVIMGSMHTGLEDRFYNYSKLAAYFAERARGGVGLMVTGGISPNRSGWLLPFGGTMNHLLDVFNHQKVTKAVHQEGGKIVMQILHSGRYGYQPLVVSASDKKSPISMFKPRALTERGIQGTIRDYVRCAKLAQKAGYDGVEIMGSEGYLLNQFLCTRTNLRKDRWGGSIENRMRLPVEIVKQIRAAVGEKFIVMYRHSILDLVEGGNSWDEVVTVAQALELAGVTILNTGIGWHEARIPTIVTSVPRAAFRSVAARLKAAVKIPVVASNRINTPDIAEDIIASGDADMVSMARPFLADPDFVNKVASNRSDEINTCIGCNQACLDHTFANQRASCLVNPRAAHETELIYLKKSKAKKVAVVGSGPAGLSAATVAAECGHDVTLFDSSDSIGGQFKIAMQVPGKEEFSETLRYFARRIEITGVKLQLNQRVTRDELLAQGFDEIIVATGIVPRTPRIDGVNHPKVLSYIDVLQHKKPVGNKVAIIGAGGIGFDVAEYLLHNPNISLPITVEHWCADWGVDLNATTNGGLATDKLPANPFRQIHLLQRKASKVGAGLGKTSGWVHRAALAHGGVAMLAGVEYNKIDDAGLHITVNGETRLLEVDNVILCAGQDSLTELMPELKVEGTAQTKPTGPRFHRIGGAKLAAELDAKRAIREGAELAASL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GU24</accession>
    <name>A0A2S9GU24_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4017</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000026">
        <property type="protein sequence ID" value="PRC91232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91232">
        <property type="protein sequence ID" value="PRC91232"/>
        <property type="gene ID" value="S2091_4017"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="32" mass="3610" checksum="12489AD2EFDCD65C" modified="2018-07-18" version="1">MLQALARCSYKLEHARLYSINLAVTSEQEASL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GU36</accession>
    <name>A0A2S9GU36_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4114</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000027">
        <property type="protein sequence ID" value="PRC91219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91219">
        <property type="protein sequence ID" value="PRC91219"/>
        <property type="gene ID" value="S2091_4114"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015764876" evidence="1">
        <location>
            <begin position="28"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="146" mass="16070" checksum="F6B0AFB300F5663D" modified="2018-07-18" version="1">MKNLMTARPPKLFALLLLTLACANINAQPLLRCEITYAGTTHTLEARISVDANADAGGAYTTEAMDIGGRFRFKALMLGTEQHVDSIKLYAYYETHRQAVLLQEVKYVAPFTLSTTAYGLTGLNYLYSPPLGRELQYGCALLEAKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GU52</accession>
    <name>A0A2S9GU52_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Vitamin B12-dependent ribonucleotide reductase</fullName>
            <ecNumber evidence="7">1.17.4.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_4019</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>[thioredoxin]-disulfide + a 2'-deoxyribonucleoside 5'-diphosphate + H2O = [thioredoxin]-dithiol + a ribonucleoside 5'-diphosphate</text>
            <dbReference type="Rhea" id="RHEA:23252"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="ChEBI" id="CHEBI:57930"/>
            <dbReference type="ChEBI" id="CHEBI:73316"/>
            <dbReference type="EC" id="1.17.4.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 7">
            <name>adenosylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:18408"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the ribonucleoside diphosphate reductase class-2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.17.4.1" evidence="7"/>
    <dbReference type="EMBL" id="PUGF01000026">
        <property type="protein sequence ID" value="PRC91234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91234">
        <property type="protein sequence ID" value="PRC91234"/>
        <property type="gene ID" value="S2091_4019"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031419">
        <property type="term" value="F:cobalamin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004748">
        <property type="term" value="F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071897">
        <property type="term" value="P:DNA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02888">
        <property type="entry name" value="RNR_II_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000788">
        <property type="entry name" value="RNR_lg_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013344">
        <property type="entry name" value="RNR_NrdJ/NrdZ"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02867">
        <property type="entry name" value="Ribonuc_red_lgC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01183">
        <property type="entry name" value="RIBORDTASEM1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02504">
        <property type="entry name" value="NrdJ_Z"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0846">Cobalamin</keyword>
    <keyword evidence="6 7" id="KW-0170">Cobalt</keyword>
    <keyword evidence="5 7" id="KW-0237">DNA synthesis</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RIBORED_LARGE" evidence="8">
        <location>
            <begin position="85"/>
            <end position="611"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022628"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU364064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC91234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="998" mass="110361" checksum="BCB8D283F2D49424" modified="2018-07-18" version="1">MTIIKNDIIPGKELAPQEITTLILQEKYCKGNETSQLDVLQRVAKGLAKDKQQQAEFLATFQAGFIGGGRIMSAGGTDIGATLINCFVQEVNDCISNPDPGSPGIYDALKQAAETMRRGGGVGYDFSRIRPKGALVKGTQSVASGPLSYMYVFDQSCSTVESAGARRGAQMGVLRIDHPDIEAFIHAKDGLLVNELPVDEATKKLLQDLMATNYDFADKMRMGFTKLRNFNISVAVTDTFMLAVEADSDWELIHQAQPDSSFSTAYQRADGLWVYHKIKARKLWEQIMASTYDHAEPGVLFIDTINNDNNLSYCEKIESTNPCGEQPLPAYGCCDLGSTILTRFVLDPFTDQASFDWKKFAKVVRGAVHILDRVLDVTLWPLPEQQHEAQQKRRIGLGYTGLGDALIMLGLRYDSAAGRAMAAKISEAMCHAAYRASIELAQKFGPFPMFDADQYLASPRFASRLPDDIKSDIRQYGIRNSHLLSIAPTGTISMAFADNASNGIEPPFSWTYQRKKREKDGSEKTIRVVDHALRVYESMHGQVDDYAQLPPYFVCALDIAAQDHMQMCAAVAPFIDTAISKTVNVPADYPFEEFQHLYSSAWKAGLKGIATFRPNSVLGSVLSLESTVESQVQVNITPNDLELNDPDRRIILKEVPQPALASLRWPGRPKIPQGNPSWTYLVEHHKGDFSVVIGQVETGNMHPFEVWVNGNEQPRVLGAIAKTLSMDMRTGDPQWLKMKLESLAKTGGDDGFELNLGEQIIYAPNLVAGLAKIIQHRLQELGVYNIEAPSPMIAALFSKKEPKSGTDGTMSWSVDIKNPSTGDDLLMIVKECRLPNGRLQPYSVWLAGDYPKVMDGLTKLLSMDMRVIDPAWIGMKLRKLLSFSEHRGDFLAKVPGSEKQQSYPSTVAYIATLLLHRFALLGILNKDGIPVEQMGVLAHPHSAQNRMGETTPNVADKEGRQRPYVKTNKKCLECHVYAVIKRDGCDFCTYCSAIGSCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GU80</accession>
    <name>A0A2S9GU80_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Uroporphyrinogen-III synthase</fullName>
            <ecNumber evidence="1">4.2.1.75</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_4053</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>hydroxymethylbilane = H2O + uroporphyrinogen III</text>
            <dbReference type="Rhea" id="RHEA:18965"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:57308"/>
            <dbReference type="ChEBI" id="CHEBI:57845"/>
            <dbReference type="EC" id="4.2.1.75"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; coproporphyrinogen-III from 5-aminolevulinate: step 3/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the uroporphyrinogen-III synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.75" evidence="1"/>
    <dbReference type="EMBL" id="PUGF01000026">
        <property type="protein sequence ID" value="PRC91268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91268">
        <property type="protein sequence ID" value="PRC91268"/>
        <property type="gene ID" value="S2091_4053"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00251">
        <property type="reaction ID" value="UER00320"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004852">
        <property type="term" value="F:uroporphyrinogen-III synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006782">
        <property type="term" value="P:protoporphyrinogen IX biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006780">
        <property type="term" value="P:uroporphyrinogen III biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06578">
        <property type="entry name" value="HemD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10090">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036108">
        <property type="entry name" value="4pyrrol_syn_uPrphyn_synt_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003754">
        <property type="entry name" value="4pyrrol_synth_uPrphyn_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039793">
        <property type="entry name" value="UROS/Hem4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38042">
        <property type="entry name" value="PTHR38042"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02602">
        <property type="entry name" value="HEM4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69618">
        <property type="entry name" value="SSF69618"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0456">Lyase</keyword>
    <keyword evidence="1" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HEM4" evidence="2">
        <location>
            <begin position="19"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU366031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="262" mass="28416" checksum="5CCD3B82293D43CB" modified="2018-07-18" version="1">MASSNKIILTRPIAQAQPLAARLTALGYSVALFPLLEIAPLPEDGELHALLQATLANLSRYAMVAFVSPNAVHNVFQRGLKWPSEVAIAVVGEGSRAALAEYGINSDNTTIYCPTDPFRSDSETLLQELNLPALKGREVLILRAETGRELLSEALIAHGIQVVKVAAYRRFAPQITAHNSQLLLELLSCSDRWVVSSSEALRTLVELARKVAGEAAVVKTQQINLLVSHHRIAETAENMGFKCVRLIGSGDENLLLALQSHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUA1</accession>
    <name>A0A2S9GUA1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3954</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000025">
        <property type="protein sequence ID" value="PRC91283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91283">
        <property type="protein sequence ID" value="PRC91283"/>
        <property type="gene ID" value="S2091_3954"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015562">
        <property type="term" value="F:efflux transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003423">
        <property type="entry name" value="OMP_efflux"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010131">
        <property type="entry name" value="RND_efflux_OM_lipoprot_NodT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02321">
        <property type="entry name" value="OEP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01845">
        <property type="entry name" value="outer_NodT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0564">Palmitate</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1134">Transmembrane beta strand</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015375187" evidence="2">
        <location>
            <begin position="20"/>
            <end position="473"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU362097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="473" mass="50928" checksum="CB4D1D7CFA46757F" modified="2018-07-18" version="1">MKSSLFLRISPLVAALALAGCVSYSGITPHSTAASNTDLSLSSATIQWPSEQWWNVYNDAVLSDLITQALAKNPSIKLAQARLERVAAMAQAVDAGTLPEVGVGLSMTPEHFTENGLYPPPFAGNIYSTNLLMVNAKYEFDFWGKNRAALDSALSTEKAAKAELQSAHLLIAASVAKSYFSLAHFSEQKKVLEMTLAQREELLNVSQQRLAAGLDTQQELHISKEGLPAIRAEIIKLDEQISLSRNALAALIGKGPEATLQVVASFPTDINMNMPDSIPANLIGRRADISAARARVDAANKQIAVAKTEFYPNINLTAFAGFSSLGFSHWLDGSSRDYGVGPAISLPIFDGGRLRANLSSKDAEYDIALESYNQTLIEAVHDIADQISSLRSLAQQQKQQAELQHNAESVYELAQQREKAGLVSKVTVLNAQTAVLTQQSAAIDLKARALDLTVNLNRALGGGFNDQTTASTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUC9</accession>
    <name>A0A2S9GUC9_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">MFS_4 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3887</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000024">
        <property type="protein sequence ID" value="PRC91342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91342">
        <property type="protein sequence ID" value="PRC91342"/>
        <property type="gene ID" value="S2091_3887"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010645">
        <property type="entry name" value="MFS_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06779">
        <property type="entry name" value="MFS_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="78"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="103"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="136"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="169"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="222"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="257"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="285"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="309"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="340"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="373"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="domain" description="MFS_4" evidence="2">
        <location>
            <begin position="23"/>
            <end position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="398" mass="43218" checksum="1671E52A66CCE53F" modified="2018-07-18" version="1">MSQNSNHRQAWQIALCGILAIGVAQGIGRFAFSPLLPMMLHDKLVNLTQGGWLATANYIGYFIGALLCMVFHKHPTRFIRIGLVATTVFTLWMSFSSQLWCLLLLRALAGIASALVFVFTSGWCMQRLTQLGFPTLGGIIYTGPGLGILITGIPVTFMVAADWSAQRGWLVFGVMALLLSAVIWPIFSEHLSINTDTNSSIKPRHLHAAKLSAEQLKHQTRWLIFGYGLAGFGYIITATFLPVMARIALPNSVWPDLFWPMLGASIAIGAALTTRVPMHIDNRSMLMLCYITQATGVLFVILLPNVLGFILSSIFVGLPFSAIVFFVMRDARRLRGDAANRLMGLLTAIYGIGQISGPPLATHLVTLTGSFTASLFVAAGALTVGAVLFGILARSKFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUH3</accession>
    <name>A0A2S9GUH3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transglycosylase SLT domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3930</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000024">
        <property type="protein sequence ID" value="PRC91385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91385">
        <property type="protein sequence ID" value="PRC91385"/>
        <property type="gene ID" value="S2091_3930"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023346">
        <property type="entry name" value="Lysozyme-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008258">
        <property type="entry name" value="Transglycosylase_SLT_dom_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01464">
        <property type="entry name" value="SLT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53955">
        <property type="entry name" value="SSF53955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015550106" evidence="1">
        <location>
            <begin position="23"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="domain" description="SLT" evidence="2">
        <location>
            <begin position="93"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="207" mass="23559" checksum="2CF36FF433B58570" modified="2018-07-18" version="1">MKLIRFIVVCCLFFGFTNAVFAGNQKEEAMANSVRLALAKAVTDNRPPKPSFTVMDDRLNYLQWLGEMSDRLKKKIPDNQTRIEFLETTWYESKRAGLDPAMVLGLIQVESAFRKYATSVVGARGLMQVMPFWSRVIGDSDAQKLFNMATNLRYGCSILRMYIDMEGGNLYMALGRYNGSRGQAEYPNMVLASWKKWEYKTPISGNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUH9</accession>
    <name>A0A2S9GUH9_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF4157 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3906</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000024">
        <property type="protein sequence ID" value="PRC91361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91361">
        <property type="protein sequence ID" value="PRC91361"/>
        <property type="gene ID" value="S2091_3906"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025295">
        <property type="entry name" value="DUF4157"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13699">
        <property type="entry name" value="DUF4157"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4157" evidence="2">
        <location>
            <begin position="128"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="588"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="606"/>
            <end position="624"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="634" mass="69276" checksum="1BF2900F7F1B2C4C" modified="2018-07-18" version="1">MSTAAPLQQTKAESNERRKKSASQPMTQLAADFVDFRSQAATQRQLQKIADNSAQARQLKTCSDMLQNSPRAMQTMKKTTDSVGEGLQDNFRATQRVGKDAFLPAPSSIEDSVQLIEHTATKPNNTGLPNQLKAGIESLSGMSMDHVKVNYDSDKPSQLNAHAYAQGSEIHVAPGQEQHLPHEAWHVVQQAQGRVRPTTQLKEGVPINDDASLEAEADLMGARALSNAQLMPSKKQACPISVSDTKQLMLSKDPKAGANIKIWAGDDGVLEVTFVKHSKGKVFYQPLITGKMPKKSPKPTVIDEKFAFDLMMGNAEIKRRVETDAKEEIEVSDIKSTVPETVLNFLMEKVALFADANDVEKPEMTPTRMLLAMGSSDILKVYLDQDWTDEEGGEKWFIENYAEYFDDETLGLYQSMNAATNSVLRSDTATSSDTSSTTKKAKWMHESIKKQKAVLIGNAGPNKLLSSGTSLHHKLSRSRIKRMLRLFQSASSPAMSSALHAITRETGITDPKKALENWAPNLELGPIVNARAEGTDPGAGFDGNVTDGSLTPRSKELAGIDIALLNAESAVDWDALAAALGRIQTAHGTGNQITPPKLGQWHQTDGGIVRDREPNEGKEEAKQEFEDELSDDSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUN4</accession>
    <name>A0A2S9GUN4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3860</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000023">
        <property type="protein sequence ID" value="PRC91445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91445">
        <property type="protein sequence ID" value="PRC91445"/>
        <property type="gene ID" value="S2091_3860"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015410809" evidence="1">
        <location>
            <begin position="24"/>
            <end position="535"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="535" mass="57266" checksum="A940A9B4F1906E95" modified="2018-07-18" version="1">MLSKLIKSSAVVLFFVGMNVWSAPDPGLPGEPIGVKYHGNIVTSIQPVLIKFGSNYLIQTNSPIAEGGIFGIYNKNAPNMTTMAISFPFKGASDWNYFLGVGMYFIQGGIYNILSDRFPFVVNENYPFSWQPDAPGKPGGYMLSYNGVTYESSYTPNLLGDKSNSNNPRGAQVQGKSRNVLAAAIIAKKSLTAVSLDVYYPNYLENSQIFERMTTKAEGAVGAEGTFGLNKSTLNILPAIENGSIDPLSAGVIGISSQKVLTTVPAGCEIVASPSGVACPISTSGSLEMYSLKSTVAGVSFLVDGALVPVTDTVITPQVKLFMSADWIDSQLGSNEQVVLVDSPLVSLYPNQTPQFIAPFPIFTKLTINRINYQISITERNPGLAVDGYYQGTIGSNSAISIPYTVKQSGPSKATNVTMSVTGDTATQDSDGRAYCKFTTDSKPAQFIAVPLALAFSGKDGVSRQQVDSDCSGTESDITGMPWTETLGTPYMGELWVDLLFNLSSRRILTDINDNYWAGSAKATGNIKVTATWND</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUP1</accession>
    <name>A0A2S9GUP1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_3836</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell inner membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the MlaE permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000023">
        <property type="protein sequence ID" value="PRC91421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91421">
        <property type="protein sequence ID" value="PRC91421"/>
        <property type="gene ID" value="S2091_3836"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003453">
        <property type="entry name" value="ABC_MlaE_Proteobac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030802">
        <property type="entry name" value="Permease_MalE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30188">
        <property type="entry name" value="PTHR30188"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02405">
        <property type="entry name" value="MlaE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SSF52091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00056">
        <property type="entry name" value="TIGR00056"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="172"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="198"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="259"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="315"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="358"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC91421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="378" mass="39754" checksum="FA7CE9898ABAD592" modified="2018-07-18" version="1">MTISTPTMTPAAIDRSKPQTLGLSGAWTVNGMGQISPQLNSATITPSPGLKIDGARIDALDATGAWVINKLLLRLGTQGHAIQLHDLRPEFSHLLGDAGQQSAEQTAPILPVPTKPVLERIGRSVELAVHDTMALLGFVGLSAVSLAKCIPHPAQFRGRSILFNIRSAGVDALPIVGLLTFLLGVVVAYQSANQLRQYGANIFVVDLIGLSMLREFAPLITAIIVAGRSGSAYTAQIGTMAVTEEIDAMRTLGIDPHQMLVVPKIIALMITLPLLTVFADVLGVFGGMIMAQATLGVGFAEFLDRFTKAVNMSAYLLGIGKAVVFAAIIAVVGCYQGFLASGGPDSIGRQTTRSVVQGIFLVIVVDALFSIAFSALDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GV08</accession>
    <name>A0A2S9GV08_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">4-hydroxybenzoate octaprenyltransferase</fullName>
            <ecNumber evidence="8">2.5.1.39</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">4-HB polyprenyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">ubiA</name>
        <name evidence="9" type="ORF">S2091_3660</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>4-hydroxybenzoate + all-trans-octaprenyl diphosphate = 4-hydroxy-3-all-trans-octaprenylbenzoate + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:27782"/>
            <dbReference type="ChEBI" id="CHEBI:1617"/>
            <dbReference type="ChEBI" id="CHEBI:17879"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57711"/>
            <dbReference type="EC" id="2.5.1.39"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="8">Cofactor biosynthesis; ubiquinone biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell inner membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the UbiA prenyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.39" evidence="8"/>
    <dbReference type="EMBL" id="PUGF01000021">
        <property type="protein sequence ID" value="PRC91544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91544">
        <property type="protein sequence ID" value="PRC91544"/>
        <property type="gene ID" value="S2091_3660"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00232"/>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002083">
        <property type="term" value="F:4-hydroxybenzoate decaprenyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047293">
        <property type="term" value="F:4-hydroxybenzoate nonaprenyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008412">
        <property type="term" value="F:4-hydroxybenzoate octaprenyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006744">
        <property type="term" value="P:ubiquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd13959">
        <property type="entry name" value="PT_UbiA_COQ2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01635">
        <property type="entry name" value="UbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006370">
        <property type="entry name" value="HB_polyprenyltransferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039653">
        <property type="entry name" value="Prenyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000537">
        <property type="entry name" value="UbiA_prenyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030470">
        <property type="entry name" value="UbiA_prenylTrfase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044878">
        <property type="entry name" value="UbiA_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11048">
        <property type="entry name" value="PTHR11048"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01040">
        <property type="entry name" value="UbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01474">
        <property type="entry name" value="ubiA_proteo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00943">
        <property type="entry name" value="UBIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="2 8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="8" id="KW-0831">Ubiquinone biosynthesis</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="27"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="50"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="95"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="148"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="171"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="214"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="241"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="273"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC91544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="294" mass="32926" checksum="5209A4E4362D4873" modified="2018-07-18" version="1">MAVLLIKKFTMHRLTLYLQLTRFDKPIGIMLLLWPTLSALWLASNGKPAWHLVLIFTIGTALMRAAGCAVNDYADRDIDKHVKRTEQRPLTSGKIKSWEALLVAAVLALASFALIIPLNGLTKLLSIAAIVIAASYPYFKRFFALPQAYLGIAFGFGIPMAYAAVQNQIPCTAWVLLFANVFWALAYDTEYAMVDKDDDLKIGIRTSAITFGRFDVVAVMFCYAANLGIITWVGWSYGLRLWFTIGILGAFACAIYHYFLIRNRSREGCFAAFRHNNWLGCLIFIGIALDFALR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVH9</accession>
    <name>A0A2S9GVH9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3649</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000020">
        <property type="protein sequence ID" value="PRC91711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91711">
        <property type="protein sequence ID" value="PRC91711"/>
        <property type="gene ID" value="S2091_3649"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="49" mass="5439" checksum="AA4B8A17BD00936E" modified="2018-07-18" version="1">MFSPYEVPYQTTSALPDAINLGLYFFTVTAFALHTTVGVLQTNTQLQLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVP9</accession>
    <name>A0A2S9GVP9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Peptidase M16 inactive domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_3536</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the peptidase M16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000019">
        <property type="protein sequence ID" value="PRC91781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91781">
        <property type="protein sequence ID" value="PRC91781"/>
        <property type="gene ID" value="S2091_3536"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011249">
        <property type="entry name" value="Metalloenz_LuxS/M16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011765">
        <property type="entry name" value="Pept_M16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001431">
        <property type="entry name" value="Pept_M16_Zn_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007863">
        <property type="entry name" value="Peptidase_M16_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00675">
        <property type="entry name" value="Peptidase_M16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05193">
        <property type="entry name" value="Peptidase_M16_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63411">
        <property type="entry name" value="SSF63411"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00143">
        <property type="entry name" value="INSULINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015443896" evidence="4">
        <location>
            <begin position="26"/>
            <end position="908"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M16" evidence="5">
        <location>
            <begin position="52"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M16_C" evidence="6">
        <location>
            <begin position="205"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M16_C" evidence="6">
        <location>
            <begin position="655"/>
            <end position="834"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF05193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC91781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="908" mass="100873" checksum="3FBAB043121F6E59" modified="2018-07-18" version="1">MSDLSKRVIFAATLCMPLMVGNVWAAALPKGITQVATVEGITEYRLANGLKVLLMPDASKPTVTVNITYLVGSRHENYGETGMAHLLEHLLFKGTPKNPKIDLDFNKRGVRFNGTTSLDRTNYYELFQASDDNLKWAIQMEADRMVNSFIAKKDLDSEMTVVRNEYEMGENSPANVLIKRLQSTAYEWHNYGHSTIGNRSDIENVKIENLQAFYHRYYQPDNAVLLISGKFDTNQALNLISSSFGVIPKPTRSLPQFWTVEPTQDGARSVEVRRKGDIQYVIVGYKIPAALNPENDAVSLAAHILADDPTGRLHKSLVETGKAVQVFSFPIGSYAPGLQLIGVAVKKDEPIEPVRDALLAAIESFATTPPTKEELERVKRNYLNDAEKTLSNPESIGLQLSEIMALGDWRYFFQERDQLNSISSEQVAAAAARYFKRDNRTVGMFIPEDSPQRAEIPATPSIQVAMQSFKPVTKVDNSEVFDPSEANIDKRTLHSKIGGLNVALLSKKNKGETVSVALNLHWGDEKSLFGKKTISTLTNEMLMRGNSKYTREQLDDEFAKLKITGNLFRFDTTRENLSAALSLVAQVLKEPNFPETEFEQLKKLNLAELEMQRNDPQAVASHALSQHFNSHYAKGDWRAIASLDEQIEQLKAVKLSDLTAFHKAFYGASHGEISIVGDLDVVATNKAIQQGFGDWVSPAAYTRIDNIYADTAAVEREINTPDQENGFYMANQALNMRDDDPAYPALIVANYIFGGGAGFTSRVMERIRKKDGLSYGVGSWISVNAFDNSASFSLYALSAPQNLNKVALAMKEELHRALKDGFTAEELANAKSGLKQAALQKRAQDAHVASDWNKYSKENRTFAWSQALEDKINALTVAQVNATFTKMIDPTKLSVFTAGDEAKKGNKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GW41</accession>
    <name>A0A2S9GW41_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Alternate F1F0 ATPase, F1 subunit epsilon</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">S2091_3272</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Produces ATP from ADP in the presence of a proton gradient across the membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ATPase epsilon chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000017">
        <property type="protein sequence ID" value="PRC91930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91930">
        <property type="protein sequence ID" value="PRC91930"/>
        <property type="gene ID" value="S2091_3272"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045261">
        <property type="term" value="C:proton-transporting ATP synthase complex, catalytic core F(1)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12152">
        <property type="entry name" value="F1-ATPase_delta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024037">
        <property type="entry name" value="Alt_ATP_synth_F1_esu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001469">
        <property type="entry name" value="ATP_synth_F1_dsu/esu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020546">
        <property type="entry name" value="ATP_synth_F1_dsu/esu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036771">
        <property type="entry name" value="ATPsynth_dsu/esu_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02823">
        <property type="entry name" value="ATP-synt_DE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51344">
        <property type="entry name" value="SSF51344"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03166">
        <property type="entry name" value="alt_F1F0_F1_eps"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="7" id="KW-0139">CF(1)</keyword>
    <keyword evidence="5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ATP-synt_DE_N" evidence="9">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005712"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC91930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="130" mass="14285" checksum="3CD6557AEF6E071D" modified="2018-07-18" version="1">MHLKVLLPFQIFADKPDVARIVAQTPHGSFGLLPNRLDCVTALSPGILSYAMANGEEFYLAVDEGLLVKIGAEVLVSVRNAIGGTDLGHLHETIQKDFLTLDAQEQSVRSVMSKLESNFIQRFAAFHHVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GW42</accession>
    <name>A0A2S9GW42_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3287</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000017">
        <property type="protein sequence ID" value="PRC91945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91945">
        <property type="protein sequence ID" value="PRC91945"/>
        <property type="gene ID" value="S2091_3287"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="41" mass="4674" checksum="7C5C742F36FC0851" modified="2018-07-18" version="1">MKNKQFASVWDAIEDTPEEVTNIKLRSSLMQALKITLLTPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GW54</accession>
    <name>A0A2S9GW54_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3299</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000017">
        <property type="protein sequence ID" value="PRC91957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91957">
        <property type="protein sequence ID" value="PRC91957"/>
        <property type="gene ID" value="S2091_3299"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015562">
        <property type="term" value="F:efflux transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003423">
        <property type="entry name" value="OMP_efflux"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010131">
        <property type="entry name" value="RND_efflux_OM_lipoprot_NodT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02321">
        <property type="entry name" value="OEP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01845">
        <property type="entry name" value="outer_NodT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0564">Palmitate</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1134">Transmembrane beta strand</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015371088" evidence="2">
        <location>
            <begin position="32"/>
            <end position="499"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU362097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="499" mass="53680" checksum="CE9885EFEFF0CD61" modified="2018-07-18" version="1">MTSIFAYSLKQRRLMMTLPAALLLLSGCAVGPDFTRPAAPAVNGYTQEPLATKTVSAPVAGGEAQYFASAEHIPQQWWTLFQSPALNKLIEQALKNNPNLQQAEAALRVAQETVYAQQGAYYPSVSANFTPTRQKEALNSVSSSAASGASLFNLHTAQLNVSYTADVFGNNRRQVENLQAQADSQRFLREAAYLTLTSNVVTAAVQEASLRAQISATNAMIKIEQEQLDLFQRQFELGAVAQANVVAQVATLAQTKAMLPPLQKQLAQQRDLLAALVGGFPGDPMPETFELSMLQLPRKLPVSLPSQLVQQRPDVRSAEEQLHAASALVGVAQSNMLPQFTLSASGGSMSTQISQLFSPGNSFWTLVGGITQPLFDGGTLLHKKRAAEAAYDEAAAQYRSTVISAFQNVADTLQALQFDADGLQTALIAERAAAESLAIARRQVELGDIGYVTLLAAEQSYQLSVLTLVQAQANRYADTAALFQAMGGGWWNQADNVAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GW66</accession>
    <name>A0A2S9GW66_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NADH-quinone oxidoreductase subunit B</fullName>
            <ecNumber evidence="2">7.1.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">NADH dehydrogenase I subunit B</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="2">NDH-1 subunit B</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">nuoB</name>
        <name evidence="5" type="ORF">S2091_3304</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.</text>
    </comment>
    <comment type="function">
        <text evidence="2">NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>a quinone + 5 H(+)(in) + NADH = a quinol + 4 H(+)(out) + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:57888"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="2">Binds 1 [4Fe-4S] cluster.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the complex I 20 kDa subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.1.1.-" evidence="2"/>
    <dbReference type="EMBL" id="PUGF01000017">
        <property type="protein sequence ID" value="PRC91962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91962">
        <property type="protein sequence ID" value="PRC91962"/>
        <property type="gene ID" value="S2091_3304"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008137">
        <property type="term" value="F:NADH dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01356">
        <property type="entry name" value="NDH1_NuoB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006137">
        <property type="entry name" value="NADH_UbQ_OxRdtase-like_20kDa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006138">
        <property type="entry name" value="NADH_UQ_OxRdtase_20Kd_su"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01058">
        <property type="entry name" value="Oxidored_q6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01957">
        <property type="entry name" value="nuoB_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01150">
        <property type="entry name" value="COMPLEX1_20K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="2 3" id="KW-0408">Iron</keyword>
    <keyword evidence="2 3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 3" id="KW-0520">NAD</keyword>
    <keyword evidence="2" id="KW-0874">Quinone</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-1278">Translocase</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <keyword evidence="2" id="KW-0830">Ubiquinone</keyword>
    <feature type="domain" description="Oxidored_q6" evidence="4">
        <location>
            <begin position="35"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="35"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="36"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="100"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="130"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00025189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC91962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="156" mass="17338" checksum="E88FB639D0228D16" modified="2018-07-18" version="1">MDVIGSNNIILSSLDEMADRCRSNSLWYMSFGLACCAVEMMHSAAARYDIDRFGVMPRASPRHSDLMIVAGTLTNKMAPALRKVYDQMPEPRYVISMGSCANGGGYYHYSYSVVRGCDRIVPVDVYVPGCPPTAEALIYGLIQLQRKVTRRTTIAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWG1</accession>
    <name>A0A2S9GWG1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3189</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000016">
        <property type="protein sequence ID" value="PRC92054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92054">
        <property type="protein sequence ID" value="PRC92054"/>
        <property type="gene ID" value="S2091_3189"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015516367" evidence="1">
        <location>
            <begin position="20"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="162" mass="17203" checksum="04C2A0A6D39E1962" modified="2018-07-18" version="1">MNKILIALFLMLQSFYALASDQSDCAAGAGAYISGIVVSGPVFQAASSTLQGVQLSHTHVQLLSDQDGQTYDVAIDNVYAVDYVLNATTIPKSLAAIHVNDRLSTCGALYTSGGLGTHWVHNNCNVPGTAAAPNGFIKKAPTRGPVYANLERSMTYCYLWGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWM2</accession>
    <name>A0A2S9GWM2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3249</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000016">
        <property type="protein sequence ID" value="PRC92114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92114">
        <property type="protein sequence ID" value="PRC92114"/>
        <property type="gene ID" value="S2091_3249"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="139" mass="15813" checksum="38D2523D2B8ABCAC" modified="2018-07-18" version="1">MPNEHQMNSAPHLDNSSIPILTEVISLNDVQEPFTQEQTNLVQTVKAELSVQVQHNQSPEQDWEQLEKTLRENVLRQLLTRVDFVLEHRVRDGLADVLQTAVDGLAQEIRQGLSKSLEEVIHRTISQEISKIQSANSKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWW4</accession>
    <name>A0A2S9GWW4_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Large ribosomal RNA subunit accumulation protein YceD</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">23S rRNA accumulation protein YceD</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_3125</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Plays a role in synthesis, processing and/or stability of 23S rRNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DUF177 domain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92209">
        <property type="protein sequence ID" value="PRC92209"/>
        <property type="gene ID" value="S2091_3125"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003772">
        <property type="entry name" value="YceD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039255">
        <property type="entry name" value="YceD_bac"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38099">
        <property type="entry name" value="PTHR38099"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02620">
        <property type="entry name" value="YceD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010740"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00031841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC92209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="165" mass="18016" checksum="1805552C078D6A69" modified="2018-07-18" version="1">MLIIDAFAFCRNSEQQTGKLKLSELARLRAECVSDDGEVEWTLVGNTHTIGYPSLQLTVTGTVQLVCQRCLTPYVFQISSDAKMLLAKDEQAADELDTSLEDDGIEVIVGSKAFDIIALIEDEALLAIPLSPKHEVCPSKEKLDAFATAKKVSPFAALKDQLSKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWW6</accession>
    <name>A0A2S9GWW6_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="8 10">Acyl carrier protein</fullName>
            <shortName evidence="8">ACP</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">acpP</name>
        <name evidence="12" type="ORF">S2091_3131</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8 10">Carrier of the growing fatty acid chain in fatty acid biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="7">Glycolipid biosynthesis; KDO(2)-lipid A biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="8 10">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="8">4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.</text>
    </comment>
    <comment type="PTM">
        <text evidence="10">4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the acyl carrier protein (ACP) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92215">
        <property type="protein sequence ID" value="PRC92215"/>
        <property type="gene ID" value="S2091_3131"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00094"/>
    <dbReference type="UniPathway" id="UPA00360"/>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000036">
        <property type="term" value="F:acyl carrier activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036104">
        <property type="term" value="P:Kdo2-lipid A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01217">
        <property type="entry name" value="Acyl_carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003231">
        <property type="entry name" value="Acyl_carrier"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20863">
        <property type="entry name" value="PTHR20863"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00517">
        <property type="entry name" value="acyl_carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="4 8" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="2 8" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="5 8" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="1 8 9" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="3 8" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="11">
        <location>
            <begin position="2"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="8 9">
        <location>
            <position position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PRC92215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="79" mass="8728" checksum="A7709E07A7CDA82E" modified="2018-07-18" version="1">MSDIEQRVKKIVAEQLGVAEADIKTESSFVDDLGADSLDTVELVMALEDEFEMEIPDEQAEKITTVQQAIDYATAHLKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GX18</accession>
    <name>A0A2S9GX18_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 16">Homoserine dehydrogenase</fullName>
            <ecNumber evidence="6 16">1.1.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">S2091_2919</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>L-homoserine + NAD(+) = H(+) + L-aspartate 4-semialdehyde + NADH</text>
            <dbReference type="Rhea" id="RHEA:15757"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57476"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:537519"/>
            <dbReference type="EC" id="1.1.1.3"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 16">
            <text>L-homoserine + NADP(+) = H(+) + L-aspartate 4-semialdehyde + NADPH</text>
            <dbReference type="Rhea" id="RHEA:15761"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57476"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:537519"/>
            <dbReference type="EC" id="1.1.1.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4 16">Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-homoserine from L-aspartate: step 3/3.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 16">Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 3/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 17">Belongs to the homoserine dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.3" evidence="6 16"/>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92260">
        <property type="protein sequence ID" value="PRC92260"/>
        <property type="gene ID" value="S2091_2919"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00050">
        <property type="reaction ID" value="UER00063"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00051">
        <property type="reaction ID" value="UER00465"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004412">
        <property type="term" value="F:homoserine dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009086">
        <property type="term" value="P:methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009088">
        <property type="term" value="P:threonine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005106">
        <property type="entry name" value="Asp/hSer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016204">
        <property type="entry name" value="HDH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001342">
        <property type="entry name" value="HDH_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019811">
        <property type="entry name" value="HDH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01842">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00742">
        <property type="entry name" value="Homoserine_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03447">
        <property type="entry name" value="NAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000098">
        <property type="entry name" value="Homoser_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01042">
        <property type="entry name" value="HOMOSER_DHGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 16" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="16" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="9 16" id="KW-0412">Isoleucine biosynthesis</keyword>
    <keyword evidence="13 16" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="11 15 16" id="KW-0521">NADP</keyword>
    <keyword evidence="12 16" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 16" id="KW-0791">Threonine biosynthesis</keyword>
    <feature type="domain" description="ACT" evidence="18">
        <location>
            <begin position="359"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="14">
        <location>
            <position position="209"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <begin position="9"/>
            <end position="16"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="109"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="194"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00006753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00013213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00013376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR000098-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR000098-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU000579"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU004171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="PRC92260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="440" mass="47224" checksum="5837A322BC5C55C9" modified="2018-07-18" version="1">MKPIKVGLLGLGTVGAGTFNVLRRNQEEITRRAGRGIEISMVAVRNLEKAQALIGGVIGNACEIVTDSMLVVTNPEIDIVVEVIGGTELTKQLVMTAIANGKHVVTANKALLAIHGNEIFKAAQDKGVMVAFEAAVAGGIPIIKSLREGLTANRIEWVAGIINGTTNFILSEMRDKGLDFATVLKQAQALGYAEADPTFDIEGVDAAHKATIMAAIAFGIPMQFDKAYVEGISQLQAIDINYAEQLGYRIKLLGIAKRTAKGIELRVHPTLIPNTRLIANVEGAMNAILVQADAVGATMYYGKGAGAEPTASAVIADLVDITRLATADPEHRVPHLAFQPNSISQEVILPMSEITTSYYLRLRVADQTGVLADVTRILADCSISIDAMLQKEPTANEKQTDIIMLTHQTQEKNVLAAIEKIELLNSVFGRVTKIRLEQLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GX59</accession>
    <name>A0A2S9GX59_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">RelA/SpoT family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_2950</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the relA/spoT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92291">
        <property type="protein sequence ID" value="PRC92291"/>
        <property type="gene ID" value="S2091_2950"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015969">
        <property type="term" value="P:guanosine tetraphosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05399">
        <property type="entry name" value="NT_Rel-Spo_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01668">
        <property type="entry name" value="TGS_RSH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004811">
        <property type="entry name" value="RelA/Spo_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007685">
        <property type="entry name" value="RelA_SpoT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004095">
        <property type="entry name" value="TGS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012676">
        <property type="entry name" value="TGS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033655">
        <property type="entry name" value="TGS_RelA/SpoT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13291">
        <property type="entry name" value="ACT_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04607">
        <property type="entry name" value="RelA_SpoT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02824">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00954">
        <property type="entry name" value="RelA_SpoT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81271">
        <property type="entry name" value="SSF81271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00691">
        <property type="entry name" value="spoT_relA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51880">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TGS" evidence="5">
        <location>
            <begin position="420"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="domain" description="ACT" evidence="4">
        <location>
            <begin position="678"/>
            <end position="749"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC92291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="749" mass="84284" checksum="265FEB93CD77974C" modified="2018-07-18" version="1">MVSIAAVNSENIDNLVASLSPEDAQRVLDALEFVSPHYEAVELVTGQNALQFARGVAATLGSLRSDADTRIASLLFELPQIDPRAAEGIEARFGKEIVDLVGGVRGLMRLSALHLMQQAALPEPGRNKNAAQQASTQLETLRKMLLAMASDMRVVLVRLASRLTTLRYFAEQKRFDETSKQYARETFDLYAPLANRLGVWQMKWELEDLSFRFIEPESYSKIARMLEEKRTEREEFIAKSIDRLQHEMNAVGIKAEVFGRPKHIFSIWNKMRGKDIDFDELNDVRAFRIIVDDIKACYTVLGIVHNIWTPVPEEFDDYIARPKPNGYQSLHTVVIADDKRGFEVQVRTKDMHHFAEYGVAAHWRYKEEGGSNFAGQEYDEKIAWLRQLLAWKTDITEAVVGDDNLQREWVEKLKSTTLDDRIYVLTPQARVIELPNNATPIDFAYHLHTSVGHNCRGARVDGVMVPLNTPLKNGQTVEIITAKIGLETGPSRDWLNPEYAVGSRTRSKIRAWFNALDQQETLSKGRAQVEKTLQREGKTVMNLEELARKCGFDKVEDLFLSVGKEEFSLRQVEHALHDEVVPPVSDEVLINKSRASSVIQGAKSGVLVVGTDGLLTLLAKCCKPAPPDVIVGFVTRGKGVSIHRANCKNFTEMRKKSPERVILTTWGQPGRETVYPVDIYVLAQDRQGLLRDISEIFSREKINVIGVSTQSAKGQARMSFTAEIGSTAQLQKALMVLRDVSGVQDVRRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXA1</accession>
    <name>A0A2S9GXA1_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Cysteine--tRNA ligase</fullName>
            <ecNumber evidence="11">6.1.1.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Cysteinyl-tRNA synthetase</fullName>
            <shortName evidence="11">CysRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">cysS</name>
        <name evidence="13" type="ORF">S2091_3002</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>ATP + L-cysteine + tRNA(Cys) = AMP + diphosphate + L-cysteinyl-tRNA(Cys)</text>
            <dbReference type="Rhea" id="RHEA:17773"/>
            <dbReference type="Rhea" id="RHEA-COMP:9661"/>
            <dbReference type="Rhea" id="RHEA-COMP:9679"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78517"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="11">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 11">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.16" evidence="11"/>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92343">
        <property type="protein sequence ID" value="PRC92343"/>
        <property type="gene ID" value="S2091_3002"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004817">
        <property type="term" value="F:cysteine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006423">
        <property type="term" value="P:cysteinyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00041">
        <property type="entry name" value="Cys_tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015803">
        <property type="entry name" value="Cys-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024909">
        <property type="entry name" value="Cys-tRNA/MSH_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032678">
        <property type="entry name" value="tRNA-synt_1_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10890">
        <property type="entry name" value="PTHR10890"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01406">
        <property type="entry name" value="tRNA-synt_1e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00983">
        <property type="entry name" value="TRNASYNTHCYS"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="SSF47323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00435">
        <property type="entry name" value="cysS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 11" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="8 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 11 13" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9 11" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 11" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="tRNA-synt_1e" evidence="12">
        <location>
            <begin position="17"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'HIGH' region" evidence="11">
        <location>
            <begin position="32"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'KMSKS' region" evidence="11">
        <location>
            <begin position="279"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="30"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="222"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="247"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="251"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="282"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PRC92343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="462" mass="53004" checksum="709BBD120D3E2607" modified="2018-07-18" version="1">MTPLHLYDNWERKLRPFQPLRADWVGLYCCGPTVYDYAHIGNLRTYLFEDLLRRALEMNGYTVRHVVNITDVGHLVSDADDGEDKMEKGSRKAGESAWDIADRFTIAFKHDLRALNMLEPQIWCKATDHIAEQIDCIATMEQKGYTYTTSDGVYFDTSKQDDYGFLARIKRDEQEAGKRVAIGDKKSATDFALWKFSPANETRQMEWDSPWGRGFPGWHSECSAMSAKYLEPWFDIHCGGEDHIPIHHTNEIAQSQACYGTRLANFWLHGYFLQIDAGKMSKSSGDFLRLQTLAEQNIDPLAYRYLCLTAHYRSQLNFSWDALLAAQTALQRMREHYYSWPPATQANADFLQRFQAEVNLDLNLPKALAIMWELLKSKLPDAIKKATMNQFDAVLGLGLSEWKPEIISEEVRELAQRRWQARAEKNWALADQLRAQIHALGYEVEDGVDGVQIKSRQIGASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXJ9</accession>
    <name>A0A2S9GXJ9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Type I secretion outer membrane protein, TolC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_2814</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92439">
        <property type="protein sequence ID" value="PRC92439"/>
        <property type="gene ID" value="S2091_2814"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019867">
        <property type="term" value="C:outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015562">
        <property type="term" value="F:efflux transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003423">
        <property type="entry name" value="OMP_efflux"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010130">
        <property type="entry name" value="T1SS_OMP_TolC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02321">
        <property type="entry name" value="OEP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01844">
        <property type="entry name" value="type_I_sec_TolC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015752304" evidence="3">
        <location>
            <begin position="37"/>
            <end position="460"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC92439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="460" mass="49723" checksum="C8E534BF094BB460" modified="2018-07-18" version="1">MNETMNESMNNAKRKKNQIVIYSVLFASLIASGIFAAPASAADLLQTYQEALQNDPQYASARASLTAGQEKSVQGRALLLPTIGITGSTTSSSSNYSSGGVSVNGVKSTNGNYTLQLTQPLIHWENWQQYEQGKLQVLASEALFGQAQLDLMVRVSQAYFDVLSAQDTLESVRANKTAITEQLSFAKRNFEVGTTTITDQHEAQARYDLAVASEFAAENDLEIKRSTLQQIIGHEPDGLAPLHKGVQLSAPEPTNINDWVSAAEFNNYGVVGAQVTQEIAKRTISLNRAGHLPTLDLVANVNRSNNSAIPIEQQPAFVDTSRNIGIQLNIPLFSGFAVTSKVREAIALEDKAGNDFETAKRSAALAARQAYLGVNSGLAQVKAYEAAEISSQSALDSNVLGYQVGVRINIDVLNAQQQLYTTQQNLSKARYDTIMNGLRLKAAASSLKQEDLAQVNALLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXN9</accession>
    <name>A0A2S9GXN9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Amino acid/peptide transporter (Peptide:H+ symporter)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_2845</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Membrane</location>
            <topology evidence="1 5">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92470">
        <property type="protein sequence ID" value="PRC92470"/>
        <property type="gene ID" value="S2091_2845"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904680">
        <property type="term" value="F:peptide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006857">
        <property type="term" value="P:oligopeptide transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17346">
        <property type="entry name" value="MFS_DtpA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005279">
        <property type="entry name" value="Dipep/tripep_permease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000109">
        <property type="entry name" value="POT_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018456">
        <property type="entry name" value="PTR2_symporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11654">
        <property type="entry name" value="PTHR11654"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00854">
        <property type="entry name" value="PTR2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00924">
        <property type="entry name" value="yjdL_sub1_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01022">
        <property type="entry name" value="PTR2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01023">
        <property type="entry name" value="PTR2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0571">Peptide transport</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="31"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="61"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="94"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="154"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="180"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="230"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="305"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="339"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="373"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="436"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="473"/>
            <end position="494"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC92470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="506" mass="55727" checksum="9C80919301E543BF" modified="2018-07-18" version="1">MQRATTITTTTILDHPAGLFTLFFTEMWERFSYYGMRALLVLFLISETTKGGWGWNRAEALTLYSWYTGLVYLTPILGGYLADRVLGSRRAVVWGGFIIAAGHACMLFNTPVLFYIGLGLIVSGTGLFKPNISTIVGQLYGKDNQALRDSGYTLFYMGVNAGAFFGILLCGYIGENIAWNYGFALAGIFMMMGALQFYFIQDIFGNIGVLTKNKTLIPPDETPHIVADRLKVICVLSFFTIFFWLAYEQAGGSMTIFAASYTDRVLAGNSGMVFKVVNSLMSIVPTLILSWVLMKLVMISVKRYLFSSLLLLACFTIIWGLLIWMLQRDFSHDQSSIPASWFGVLPAFFIVILAPLFSTLWEKYWQPSGPIKFAVGLILLGLGFAVLAYGALGIPSGASTASVSMAFLVLAYLLHTMGELCISPVGLSYISKLAPSRLLGLMFGVWFINAAIANKLAGSLGSYIDYISTTYSLASFFLIFATIPITAGLIVLLLNKWMLKNMHGVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXX8</accession>
    <name>A0A2S9GXX8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2624</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92569">
        <property type="protein sequence ID" value="PRC92569"/>
        <property type="gene ID" value="S2091_2624"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="6"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="295" mass="33652" checksum="024E7D925C621DF2" modified="2018-07-18" version="1">MSKRLPPLNSLRVFEVAARRLNFTRAAEELHVTNAAVSHQIKLLEDELGLALFQRKNNVLSLTEAGEMYFPRIKEGFKIFQQATDMLLNGTNVLLRVGVPPSFGSKWLVPRLYRFINKHPNIRIEIVSELDRSYPNCDISIDFRRNQFADFKIESFISTEVFPVCSPQLGMNLKDPADLSRHTLLHEIRAMNDPDYPSWEAWFAALGVPNNNARQGPLFTLALMAMQAAMDGHGVALGQSLLVEYDIAAGRLMRPFQMDTPLRLNYFLIYAADMAENPAFQVFHQWLMDEAKLTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GY12</accession>
    <name>A0A2S9GY12_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="13">PgsA: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">S2091_2669</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">S20-91</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="10">Phospholipid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the CDP-alcohol phosphatidyltransferase class-I family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92614">
        <property type="protein sequence ID" value="PRC92614"/>
        <property type="gene ID" value="S2091_2669"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00591">
        <property type="reaction ID" value="UER00648"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008444">
        <property type="term" value="F:CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000462">
        <property type="entry name" value="CDP-OH_P_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043130">
        <property type="entry name" value="CDP-OH_PTrfase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004570">
        <property type="entry name" value="Phosphatidylglycerol_P_synth"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01066">
        <property type="entry name" value="CDP-OH_P_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000847">
        <property type="entry name" value="Phos_ph_gly_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00560">
        <property type="entry name" value="pgsA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00379">
        <property type="entry name" value="CDP_ALCOHOL_P_TRANSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="9" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 11 13" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="69"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="93"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="134"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="161"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00025707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PRC92614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="196" mass="21742" checksum="D8E65F3D40576ED0" modified="2018-07-18" version="1">MPFNIPILLTWIRVALIPLVVGVFYLPATWLPPFDQGVASTIIFIVAAVTDWFDGFLARRWNQTSAFGAFLDPVADKLMVAGALLVLVQLDRINYGALIAFVIIGREIAISALREWMAQIGASKSVAVSSLGKIKTTAQMTAIPMLLFNGTLFGVFDTSYWGQWFLLVAAILTVWSMFYYLKLAWPLIKEHSGKLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GY49</accession>
    <name>A0A2S9GY49_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2698</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92643">
        <property type="protein sequence ID" value="PRC92643"/>
        <property type="gene ID" value="S2091_2698"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="76" mass="8199" checksum="1A30115307D1015E" modified="2018-07-18" version="1">MLSILNIRFMNIQKTISLIKSAGLTQSQIAKFVGCSAPNISDLANGVHGQVRPSSKVVDGLRKLLSEHGLQEILDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GY89</accession>
    <name>A0A2S9GY89_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Bacterial type II and III secretion system protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">S2091_2750</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the bacterial secretin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92695">
        <property type="protein sequence ID" value="PRC92695"/>
        <property type="gene ID" value="S2091_2750"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008965">
        <property type="entry name" value="CBM2/CBM3_carb-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002102">
        <property type="entry name" value="Cohesin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001775">
        <property type="entry name" value="GspD/PilQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005644">
        <property type="entry name" value="NolW-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038591">
        <property type="entry name" value="NolW-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011662">
        <property type="entry name" value="Secretin/TonB_short_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004846">
        <property type="entry name" value="T2SS/T3SS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00963">
        <property type="entry name" value="Cohesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00263">
        <property type="entry name" value="Secretin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03958">
        <property type="entry name" value="Secretin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00811">
        <property type="entry name" value="BCTERIALGSPD"/>
    </dbReference>
    <dbReference type="SMART" id="SM00965">
        <property type="entry name" value="STN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49384">
        <property type="entry name" value="SSF49384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="3 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="5">
        <location>
            <begin position="37"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="domain" description="STN" evidence="10">
        <location>
            <begin position="220"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="627"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="637"/>
            <end position="666"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC92695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="835" mass="89036" checksum="E49435679DB6E282" modified="2018-07-18" version="1">MLKRPDLPLSLPRTSMQKRFILCSGIIVSILLAGCAGQLAYRDGKNLVEEGKMDEGLSKFKEALANDPHDAKYREAYLQTRERSLYRYLEQADLLVNNGSLDEAKNVYQHALIIVPGNEKALAGLMAIDSAQRQTQLLNAADADFAKKDLESARKKVAEVLIDNAKNTRAIALKKAIDEKVALFSADTQLAKTFQKKITIEFKDVALKQVFEVISRTSGLNFLFDKEVKTDQRTSIFLKNSSIESAIHFTLMTNQLDKQVLDSNTILIYPNTPAKQKEYQELVVRTFFLTNAEAKNVANTLKTIIKSHDIVVDDKLNMIIVRDSPDAIKLAEKLVALQDVAEPEVMLEVEVLEVQRTFLQNLGIQWPASLGLTPQPLSVLQSSTGSTSSTSTSGLSLNDLLHQSKNTLGASIGATTINANLQDSDAKLLTNPRIRVRNHEKAKILIGERVPNITSTATSTGFVSQSINYIDIGLTLNVEPTIYLDDNVGIKVSLEVSSILNQITTQSGTNAYEIGTRTASTVLRLKNGETDVLAGLIDNQERTSGNKIPGVGSMPILGRLFGSTTNNDQNTEIVLSITPHLIRNIQRPDANDAYFLSGTESSLHTRAIASDNSENTPISTPAATTLAKPMAQRPTPPHSPNGLNALTNSESATSPTSASSDLGAGTPMGSGDTPAGAGSINAAGAGAPAAGGVANGVSQVQFNWQSPNQVAAGGTVAVALMMQSSQPISSIPLTLGFDSTKLQVIGVSEGTYLKQGAAPTNFTSRINPNGQIALSDSTSNSSGITNTAVLATVTFRALSVAGPTTIQVLSATPVGAGNTPIPVAIPTPFVLQVTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYA1</accession>
    <name>A0A2S9GYA1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2691</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92636">
        <property type="protein sequence ID" value="PRC92636"/>
        <property type="gene ID" value="S2091_2691"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="263" mass="29573" checksum="0B906AB26115EF2D" modified="2018-07-18" version="1">MHVGVWKLNSGGIPPIISKLEVDSLERAEFEMKVKTATELVKEINLLLSIATHSSDFQTVSTRLDAANEKTIELQKIAAEEPRITLTNFGAAEKLAEKARDMLVKLQYDRKNDAALWCYHARFYLKTPREHLLNHGLMMRCSESDLPIIGDLVGGAWHHALPTFKEMGVDILEFSRGSVASDMGSIPADGGFYMDFLLEFRAIVESGIEIPEMVIMVDALCASRPDFGYVKERHDNALTILKRAHVDVSNFIKKSPPKKQERF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYG5</accession>
    <name>A0A2S9GYG5_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RNA polymerase sigma factor RpoD</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Sigma-70</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rpoD</name>
        <name evidence="11" type="ORF">S2091_2497</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Interacts transiently with the RNA polymerase catalytic core.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the sigma-70 factor family. RpoD/SigA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92767">
        <property type="protein sequence ID" value="PRC92767"/>
        <property type="gene ID" value="S2091_2497"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00963">
        <property type="entry name" value="Sigma70_RpoD_SigA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000943">
        <property type="entry name" value="RNA_pol_sigma70"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009042">
        <property type="entry name" value="RNA_pol_sigma70_r1_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007624">
        <property type="entry name" value="RNA_pol_sigma70_r3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007630">
        <property type="entry name" value="RNA_pol_sigma70_r4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007631">
        <property type="entry name" value="RNA_pol_sigma_70_non-ess"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007127">
        <property type="entry name" value="RNA_pol_sigma_70_r1_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042189">
        <property type="entry name" value="RNA_pol_sigma_70_r1_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012760">
        <property type="entry name" value="RNA_pol_sigma_RpoD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028630">
        <property type="entry name" value="Sigma70_RpoD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04546">
        <property type="entry name" value="Sigma70_ner"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03979">
        <property type="entry name" value="Sigma70_r1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00140">
        <property type="entry name" value="Sigma70_r1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04539">
        <property type="entry name" value="Sigma70_r3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04545">
        <property type="entry name" value="Sigma70_r4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00046">
        <property type="entry name" value="SIGMA70FCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02393">
        <property type="entry name" value="RpoD_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00715">
        <property type="entry name" value="SIGMA70_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00716">
        <property type="entry name" value="SIGMA70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="5 6" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 6" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="RNA_pol_sigma70" evidence="9">
        <location>
            <begin position="723"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="domain" description="RNA_pol_sigma70" evidence="10">
        <location>
            <begin position="892"/>
            <end position="918"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="6">
        <location>
            <begin position="893"/>
            <end position="912"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="496"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="region of interest" description="Sigma-70 factor domain-2" evidence="6">
        <location>
            <begin position="699"/>
            <end position="769"/>
        </location>
    </feature>
    <feature type="region of interest" description="Sigma-70 factor domain-3" evidence="6">
        <location>
            <begin position="778"/>
            <end position="854"/>
        </location>
    </feature>
    <feature type="region of interest" description="Sigma-70 factor domain-4" evidence="6">
        <location>
            <begin position="867"/>
            <end position="920"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="301"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Interaction with polymerase core subunit RpoC" evidence="6">
        <location>
            <begin position="723"/>
            <end position="726"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="20"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="496"/>
            <end position="517"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS00715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS00716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC92767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="934" mass="102645" checksum="963D323DE338F565" modified="2018-07-18" version="1">MKKPAKPQVDFKAKKSSATEKKAANLNLGSALKKTANKAPTKPISKAVNRSVIQPASKAATKVVAPQKTAKAITATKVVTKAVTKAVTKKVTPAVTAKPEVKKAVNKATAKPTAPAVKKTNPVGQHATKITVNKASLNKLSTAVVVKKPGNVVKKAEPAVVTATAKKTTSSSKQNAPAVSSVQVKASALKSDLKTVIKPIKTSAKAEKAQETPETRITSNAPVVNQTTDAALLAAIDTSGYILPGVKVPGRRGRKPKEYQPENEEMAALNAVERAELKAVDKAKAKDRKAKEKALLKDAFSADTEATEEELERRRQKLKALIKMGKDRGYLTYAEINDHLPENIVDPEAIEGIIGTFNDMGIAVYEQAPDAETLLLSDNVVQVTSDDDDAEAAAEAALSTVDSDFGRTTDPVRMYMREMGSVELLTREGEIVIAKKIEEGLKDMIQAISACPTTIAEILLSADRIANDEIKIDEIVDGLVDMNAEDISVVVVAASVAEEEDEEDEEDEEEEEEEEGASAAGAAGYSAEQLEQLKRDALAKFATIATQFEKMRKAFEKEGYNSKPYTKAQEIISHELLGMRFTAKVVEKLCDTLRGQVDEVRHVEKQILDVVVNRCGMSRAHFIKVFPGNEVNLNWVEGEVNAGHAYSAILGRNVPAVQQLQQKLIDLQMRVVLPLIDLRGINKKMSAGEMKARRAKREMTEANLRLVISIAKKYTNRGLQFLDLIQEGNIGLMKAVDKFEYRRGYKFSTYATWWIRQAITRSIADQARTIRIPVHMIETINKMNRISRQILQETGAEPDPATLAIKMEMPEDKIRKIMKIAKEPISMETPIGDDDDSHLGDFIEDNNTLAPADAALHASMRNVVKDVLDSLTPREAKVLRMRFGVEMSTDHTLEEVGKQFDVTRERIRQIEAKALRKLRHPSRSDKLKSFLEGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYG7</accession>
    <name>A0A2S9GYG7_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">30S ribosomal protein S21</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rpsU</name>
        <name evidence="6" type="ORF">S2091_2494</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4 5">Belongs to the bacterial ribosomal protein bS21 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005877634.1">
        <property type="nucleotide sequence ID" value="NZ_PUGF01000011.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92764">
        <property type="protein sequence ID" value="PRC92764"/>
        <property type="gene ID" value="S2091_2494"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00358">
        <property type="entry name" value="Ribosomal_S21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001911">
        <property type="entry name" value="Ribosomal_S21"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038380">
        <property type="entry name" value="S21_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21109">
        <property type="entry name" value="PTHR21109"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01165">
        <property type="entry name" value="Ribosomal_S21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00976">
        <property type="entry name" value="RIBOSOMALS21"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00030">
        <property type="entry name" value="S21p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC92764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="70" mass="8568" checksum="DEB8E471F0DC70E1" modified="2018-07-18" version="1">MTTIRLKENEPFEVAMRRFKRTIEKTGLLTELRAREFYEKPTAERKRKLAAAVKRHYKRIRSQQLPKKMY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYI5</accession>
    <name>A0A2S9GYI5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative glutamine amidotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2517</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92787">
        <property type="protein sequence ID" value="PRC92787"/>
        <property type="gene ID" value="S2091_2517"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016811">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011697">
        <property type="entry name" value="Peptidase_C26"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044668">
        <property type="entry name" value="PuuD-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43235">
        <property type="entry name" value="PTHR43235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07722">
        <property type="entry name" value="Peptidase_C26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="275" mass="30071" checksum="58558B9B3AA16813" modified="2018-07-18" version="1">MNELPLRIGLSARLMHSPPKELGFTGKTLQYLEQSLAHWIMANGALAFMIPTLSQDGGVHRSAVSVRDYVSALDGLVLQGGADVSPESYGEQPLRPEWAGDRIRDLFEMELVWEFIIQGKPVLGICRGAQLINVACGGSLYQDIAEQFPSAGIHRDHALYDGFHHEIEIVAGSRLATLFSGASIGSVNSIHHQAIKTLGNDLIIEARACGDGVIEAIRWTGSGYMFGCQWHPEFQITFPNLIDSSPIMSDFLDASKAARLKSSVSKQISEPELKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYK9</accession>
    <name>A0A2S9GYK9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ABC-type uncharacterized transport system periplasmic component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2523</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92793">
        <property type="protein sequence ID" value="PRC92793"/>
        <property type="gene ID" value="S2091_2523"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06325">
        <property type="entry name" value="PBP1_ABC_unchar_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007487">
        <property type="entry name" value="ABC_transpt-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35271">
        <property type="entry name" value="PTHR35271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04392">
        <property type="entry name" value="ABC_sub_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015652455" evidence="1">
        <location>
            <begin position="21"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="341" mass="37531" checksum="14AA53494C5D31EC" modified="2018-07-18" version="1">MYFRYVFLLCLFATSLSSQGAEPITKPYKIMMMLYRGETDAEKGFMEYFKRHHIPAEFIIRDAQADNAKIAGFIREARDIKPDLIYTFGTTVTSKVVGVIGDDDPETHITDIPVVFDIVADPVGARLTSSLKSSGRNVTGVSHLVPIAAQIQALQSMRTIQRLGVIYNPQEKNAMLAVQELQTLAQKLALTLQLVPVVLDANQHPSTEGVVAAMRDLLAQKPQFIYIPSDSFMIKNANLVVQEAQAAHVPVFAATEAPIRNDGALLGLVSNYFNVGELAAYKAEQILSKKMVVSQVPIESLNRFTYLINMGAAKKLGIYPPVSLFKVAELVNGTDNLDARE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYR2</accession>
    <name>A0A2S9GYR2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2570</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92840">
        <property type="protein sequence ID" value="PRC92840"/>
        <property type="gene ID" value="S2091_2570"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="91"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="118"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="142"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="166"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="257"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="288"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="346"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="370"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="400"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="428"/>
            <end position="445"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="460" mass="53012" checksum="FA6E9B4CD8A3CADC" modified="2018-07-18" version="1">MRNYFPFWLMPFQVRKNQGSMLLLSVILFSPLILIPSIWPATHNLIRSLSLGCAIPFGFLIIAYWASYIVNLRQQLSPINTHLLPKLKSRLFYATLILWLLISISAALIFGLFFNRAMQFWIAISFLMCYLTFLMNGNFIALALYGVFICFSKQIWPVFLLLSSNYTFEICAANLLFCCLLLIQLTHPSQIQAERLQKKFKTLRNWGNGDKAEKNKYELLFEKNGTSVYQFCVQNRISAKKSLFCYGLSPSAHWSRVLNIVILISVAYIFSQLLIGTNITSKNHLSEWTVIAFMSINSGVPLSFITATWQAIHKTKKEQLLMSLLPGSPSQEKCNRIYFHYVVRNNLISLITYFCTLLIVKNIFNLPFFSWDSILLFSSLPLFSMLLVDYSKFTYSTNDIMLKLILPFSIIATISFTCVSFFEIPIWQWDSGLLVISVMLLIWRWNKMMQAPPAFPAGRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYT9</accession>
    <name>A0A2S9GYT9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative nucleotidyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_2312</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92895">
        <property type="protein sequence ID" value="PRC92895"/>
        <property type="gene ID" value="S2091_2312"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041633">
        <property type="entry name" value="Polbeta"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18765">
        <property type="entry name" value="Polbeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Polbeta" evidence="4">
        <location>
            <begin position="14"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF18765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC92895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="96" mass="10361" checksum="C44AB8826F3094C0" modified="2018-07-18" version="1">MKPSVALNMHRDSIRKIVASHRAINARVFGSVVHGNDTDGSDLDILIDPTSTTTLMDVAAIQVELELLLGVTVDVLTPRALPDKFRATVLVEAMPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYZ2</accession>
    <name>A0A2S9GYZ2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Response regulator of the LytR/AlgR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_2335</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92918">
        <property type="protein sequence ID" value="PRC92918"/>
        <property type="gene ID" value="S2091_2335"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007492">
        <property type="entry name" value="LytTR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04397">
        <property type="entry name" value="LytTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00850">
        <property type="entry name" value="LytTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50930">
        <property type="entry name" value="HTH_LYTTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="3"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="domain" description="HTH LytTR-type" evidence="3">
        <location>
            <begin position="150"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC92918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="252" mass="28431" checksum="B83A64744C8C1F3F" modified="2018-07-18" version="1">MPTAVIADDEYLQRDELRRMLSEAWPQLVIVAECEDGSEALDAIVKHQPDIAFLDIRMPGLSGLDVARATDGKCNIVFVTAYDVHAIDAFNLAACDYLLKPIQGQRLAQTIERVQNKLATGEKSLGLLQMMETFEKRLSENASKERIRWISANAGKSIQIFPVEDILFFESDTRYTRVVSATDEGLIRTAIKDLQKGLDAEQFWQINRGILVNMHAIARAHRDEFGGIKVEIKGCKEQLKVSQTYAWRFKGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZ11</accession>
    <name>A0A2S9GZ11_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 6">DNA polymerase III subunit epsilon</fullName>
            <ecNumber evidence="3 6">2.7.7.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">dnaQ</name>
        <name evidence="8" type="ORF">S2091_2378</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="6">DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="3 6"/>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92961">
        <property type="protein sequence ID" value="PRC92961"/>
        <property type="gene ID" value="S2091_2378"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06131">
        <property type="entry name" value="DNA_pol_III_epsilon_Ecoli_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006054">
        <property type="entry name" value="DnaQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006309">
        <property type="entry name" value="DnaQ_proteo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013520">
        <property type="entry name" value="Exonuclease_RNaseT/DNA_pol3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00929">
        <property type="entry name" value="RNase_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00479">
        <property type="entry name" value="EXOIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00573">
        <property type="entry name" value="dnaq"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01406">
        <property type="entry name" value="dnaQ_proteo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0235">DNA replication</keyword>
    <keyword evidence="6" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="6" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0464">Manganese</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Exonuclease" evidence="7">
        <location>
            <begin position="2"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00024632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU364087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC92961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="232" mass="25463" checksum="A283F5DB15A2F9CF" modified="2018-07-18" version="1">MRQVVLDTETTGLNPRTGDRVIEVGCVELIDRKLTGNNFHVYINPERDSDPRALEIHGLTTEFLSDKPKFADIAASLSEYVQGAELIIHNASFDMGFLDAEYAKLKLSSFTSQVLNVVDTLATAKEMHPGKRNSLDALCDRYGISNAHRQLHGALLDSELLADVYLAMSRGQNSFVIDEEDHSSNANNSDAAHEQPLATILVQAANEEELAAHQQSLVGLDKAVRGTCVWNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZ42</accession>
    <name>A0A2S9GZ42_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Mn2+ and Fe2+ transporters of the NRAMP family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_2408</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92991">
        <property type="protein sequence ID" value="PRC92991"/>
        <property type="gene ID" value="S2091_2408"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046873">
        <property type="term" value="F:metal ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001046">
        <property type="entry name" value="NRAMP_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11706">
        <property type="entry name" value="PTHR11706"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01566">
        <property type="entry name" value="Nramp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="51"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="91"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="129"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="156"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="187"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="253"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="295"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="343"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="368"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="407"/>
            <end position="427"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC92991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="429" mass="46556" checksum="028B76BF6D02B112" modified="2018-07-18" version="1">MSNYSDTEVIDSSNETWGNQLGPGLITGAADDDPSGIATYSQAGAQFGYNMLWTLVLTYPFMVAIQVISAKIGRVSGHGLATNIYRHFPAWLLYFLVGLLLVANTINIAADVAAMGAALKLLIGGPAHFYAMGFGVISLVLQIFIPYFRYVRVLKWLTLALFAYVGIIFVVQIPWDIVLKRTFLPHLSLNAAFITTVVAVFGTTISPYLFFWQASQEVEEQRANQQAKPIRYAPNQASANFHRIKLDTVIGMGFSNIVAYFIVLTTAVTLNLHGVTNIQTSEQAASALRPIAGEFAFWLFSAGIIGTGFLAVPVLAGSAAYAMAGALQWKNSLALKPLLAKRFYGIITLATLLGVALCFTPIDPIKSLYWSAVINGVISVPIMVVMMLMASRSDIMGEFVISLRLRLLGWGGTIVMAIAVAAMFWSIGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZ95</accession>
    <name>A0A2S9GZ95_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">LigB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_2137</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93051">
        <property type="protein sequence ID" value="PRC93051"/>
        <property type="gene ID" value="S2091_2137"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008198">
        <property type="term" value="F:ferrous iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016701">
        <property type="term" value="F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006725">
        <property type="term" value="P:cellular aromatic compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07363">
        <property type="entry name" value="45_DOPA_Dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014436">
        <property type="entry name" value="Extradiol_dOase_DODA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004183">
        <property type="entry name" value="Xdiol_dOase_suB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02900">
        <property type="entry name" value="LigB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006157">
        <property type="entry name" value="Doxgns_DODA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="LigB" evidence="5">
        <location>
            <begin position="7"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC93051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="266" mass="29255" checksum="4C32A7473C084FC4" modified="2018-07-18" version="1">MTTLPTYFISHGGGPWPFMKTEYGQTYAKLEATLQDMPRQLGVTPKAILVISAHWEEAEFTVQANATPGMIYDYSGFPEHTYHISYPAPGSPELAKQVQALIEQAGFAAKLDLQRGFDHGTYSALFPIYPNADIPIVQLSLKAHLDPASHIALGRALAPLRQQGILIIGSGLSYHNLRQFGPSGYAASREFDDWLQDTLIQSDSIRRVEKLLAWSQAPSARAAHPREEHLLPLMVALGAAQEDVASCVYHENTFMGGLTVSSFRFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZF3</accession>
    <name>A0A2S9GZF3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2413</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92996">
        <property type="protein sequence ID" value="PRC92996"/>
        <property type="gene ID" value="S2091_2413"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="96" mass="10540" checksum="95613BB14BEDDFD9" modified="2018-07-18" version="1">MKTATLPPIRVEPKFREEMESVLVAGETLSSFIEGAARREAHYRKVHGEFLARGRASLANARETGKTIPAQTAIAELDKIIDAKFGTGSARKRESN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZH4</accession>
    <name>A0A2S9GZH4_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Site-specific DNA-methyltransferase (adenine-specific)</fullName>
            <ecNumber evidence="3">2.1.1.72</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_2193</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 2'-deoxyadenosine in DNA + S-adenosyl-L-methionine = an N(6)-methyl-2'-deoxyadenosine in DNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:15197"/>
            <dbReference type="Rhea" id="RHEA-COMP:12418"/>
            <dbReference type="Rhea" id="RHEA-COMP:12419"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:90615"/>
            <dbReference type="ChEBI" id="CHEBI:90616"/>
            <dbReference type="EC" id="2.1.1.72"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the N(4)/N(6)-methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.72" evidence="3"/>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93107">
        <property type="protein sequence ID" value="PRC93107"/>
        <property type="gene ID" value="S2091_2193"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009007">
        <property type="term" value="F:site-specific DNA-methyltransferase (adenine-specific) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1020.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023095">
        <property type="entry name" value="Ade_MeTrfase_dom_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012263">
        <property type="entry name" value="M_m6A_EcoRV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012327">
        <property type="entry name" value="MeTrfase_D12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30481">
        <property type="entry name" value="PTHR30481"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02086">
        <property type="entry name" value="MethyltransfD12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000398">
        <property type="entry name" value="M_m6A_EcoRV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00505">
        <property type="entry name" value="D12N6MTFRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="binding site" evidence="7">
        <location>
            <position position="8"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="12"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="53"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="175"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000398-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC93107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="262" mass="30120" checksum="A044FAB960D5B200" modified="2018-07-18" version="1">MVLPIIPWLGGKRRLADQLIPQFPAHSCYVEVFAGGAALYFLRPPAEVEVINDINGELVNLYRVVQNHLEEFVRQFKWALSSRDLFKWLQDTPPETLTDIQRAARFYYLQHNAFGGKVSGQNWGTATTAPAVNLLRIEESLSAAHLRLSQSYIENLDWHKCMIKYDREHTFFYLDPPYWETAGYGVEFGTEQYEKMASVLRNLKGKAIVSLNDHPDIRRIFAEFEMDAVPIKYCVGGGVKTVDRLEVIIYSWDRTLDPVGLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZM5</accession>
    <name>A0A2S9GZM5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="10">TonB-dependent Receptor Plug Domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">S2091_1927</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93189">
        <property type="protein sequence ID" value="PRC93189"/>
        <property type="gene ID" value="S2091_1927"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="3 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 10" id="KW-0675">Receptor</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="2 6" id="KW-0798">TonB box</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015523440" evidence="7">
        <location>
            <begin position="33"/>
            <end position="987"/>
        </location>
    </feature>
    <feature type="domain" description="Plug" evidence="9">
        <location>
            <begin position="63"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="8">
        <location>
            <begin position="382"/>
            <end position="983"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC93189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="987" mass="103639" checksum="6EB7CE91FAECCAF6" modified="2018-07-18" version="1">MMMETILSRSLRLMFSGSMALGIGMLAQPAFAQQADSTTIDTSAPVQRVEITGSAIKRIAKEGALPVQVLTQADIKKTGATSVTDLIQNLPAMQGFTTASASVNGGGGGATSAALHSLSAQYTLVLLDGVRMAPQGGSVNLESIPLDAIERVEILTDGASALYGSDAIAGVVNFILKKNKTDGDAYITAQDPQHPGGRSWSAGVSKGFGDLNKDNYNVLLSYSHDDQKQLEATQRSFSAKGGLIPFTANGKNYVFNQTSINSPIANLSIVSAAPSDINGTNATSATLNPYALANAGSCGSNPNSYAHGSTCRFNYAATVQDIPSSVRDSGLAKATFKIDENTTAWATMMVSRYAMTAQYAASAQPFAINSTNLAGVNSTAYQNLFTTYVQPYLTQTGTVITGKNGGGVTAYYRTVAMGGRTDDYQTDAHHFSAGISTAVAGWDLNGVVTLSNSVLKDTAAGGYGNFNEFNALVASGAYDPVMNTGGASLQAAEITGQLLNKTTSNDNTIKVGAQHDLFELPGGSSIISLGADFQHTSLQESYNPLQLANSGYASAPAGTNAQLGGSTAQVPFDASRNNEGLYGEWLLPVTKTLEGNVAARYDSYSKVYSGYVFQTPALGGAQLPNADLGNTFSKATYKLSLRFTPTDAVLLRASYGTGFKAPSLGDIAATSTYAGTTAGSYTCPFNTPASCANGSVPGTPPAQANPVQYDLLSGGNANSGSGGLKAENSKQWTVGFRVEPGFGLTAGLDLWDVQIKDQVLGAGVPEQTGFANPTLYSSLFVNPYQDPVGHYTTIGFNQVPLNGGVANYQGIDWDFAEKLKTPVGPLSLAWNGTYMMKQNYTFQQNGPVLTDLGTFGPDNSVVFRVQMRAVASLTTGNFTNNLSANYKSGYHDEFYGANTGAVKVVNADGSMTAVDYTGHVGSYTTFDWQGRYDYSKALNFTAGIKNLFDKNPPLSLVNAGGGNQVGYDGRYADPLGRAFYLTGHYHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZT6</accession>
    <name>A0A2S9GZT6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative periplasmic or secreted lipoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1979</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93241">
        <property type="protein sequence ID" value="PRC93241"/>
        <property type="gene ID" value="S2091_1979"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007055">
        <property type="entry name" value="BON_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014004">
        <property type="entry name" value="Transpt-assoc_nodulatn_dom_bac"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04972">
        <property type="entry name" value="BON"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00749">
        <property type="entry name" value="BON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50914">
        <property type="entry name" value="BON"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="domain" description="BON" evidence="2">
        <location>
            <begin position="60"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="domain" description="BON" evidence="2">
        <location>
            <begin position="137"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="228" mass="24236" checksum="A381BBEA420BDA63" modified="2018-07-18" version="1">MNKYPHGLLKLTNLARPLLALTLATSVLASLSGCAVLLVGGAVGGAMSVSDRRTLGAQTEDTTIELKAGNRISTVFGDAVHVNANSYNRKVLLTGEVKDEATKAQVEKEIGALENVHAVVNEIQVTPFLPSFSSRSADTLTTTKVKAKLVGTSDIYSSSFKITTEAGVVYLMGRVSQREGATAAESIREVSGVQKVVKVFEYIDEVEVKNYQAKPVEEATPTSTSTTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZX0</accession>
    <name>A0A2S9GZX0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Putative ABC-type transport system involved in lysophospholipase L1 biosynthesis permease component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_2252</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93166">
        <property type="protein sequence ID" value="PRC93166"/>
        <property type="gene ID" value="S2091_2252"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038766">
        <property type="entry name" value="Membrane_comp_ABC_pdt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30287">
        <property type="entry name" value="PTHR30287"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="253"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="310"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="347"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="390"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="413"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="463"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="697"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="752"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="787"/>
            <end position="809"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="8">
        <location>
            <begin position="285"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="8">
        <location>
            <begin position="729"/>
            <end position="817"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC93166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="824" mass="89787" checksum="0A530AD5CA01E719" modified="2018-07-18" version="1">MLLQSLRMTWRDWRAGELHFLLIALVIAVGALSSVGFFVDRVSSGLQRDANQLLGADLVISSDAPIGNNLREPTKGLQQAETASFVSMAVNNDESLSKLVSVKSVSAQYPLRGHLTLDSGIAQQQIPASGTVWVDQAVLTALNTQLGQRLKLGDQFFTVSHLIQNEPDRGSAFINFAPRVMLAESDLAATNLIQPGSRVTYRLMLSGAAKQVSATQKTLVKMIESQQLKGVNLESLETGRPEMSSTLDRAKQFLSLVSLLSAMLAALAIALAARRFMLRHIDACAMLRCLGMTQTQVTTLFLIEFFTLGLVASLLGAALGYFGHLALLIWLGSFISTTLPEPSVLPALQGIAIGMLLLIGFAIPPILQLRNVPHNLMVRRETGTPQAHTIFAYLIGVVMFAILLVWQTGNVKLAGFTLLGFLVGMLVFAVCAWAFLRAMKLMRGWFHFPAWRFAINALQRRPVASIVQVVALSLGLMALLLLTAIRADLLSAWQQATPANAPNQFIINILPEQKEPIAALLAQHKVDNPALYPMIRGRLIAVNATSISAKDFEADNAKRMIEREFNLSTMAQMQSHNRLISGQWFSGDKPEASVEEGIAKTLRLKLGDKLRFDVAGQQMDVDITSIRKLDWGSMQVNFFVIINPKSAVGLPQTFITAFHLPANQPGLIAELSRDYPNLTIVDTGAVLLQLQHVLDQVVAAVQFLFLFTLACGLLVLYAALQSSQQQRLQEASLLRALGASKKQLSQAQWIEYGLLGSLAGLLAASGAAAIGWVLAHQVFEFAFHPSPVLWLFGLVAGALCALIGGWLGLRHILRQPPLLSLREA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H009</accession>
    <name>A0A2S9H009_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2060</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93322">
        <property type="protein sequence ID" value="PRC93322"/>
        <property type="gene ID" value="S2091_2060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001544">
        <property type="entry name" value="Aminotrans_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036038">
        <property type="entry name" value="Aminotransferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043132">
        <property type="entry name" value="BCAT-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043131">
        <property type="entry name" value="BCAT-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01063">
        <property type="entry name" value="Aminotran_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56752">
        <property type="entry name" value="SSF56752"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="1" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="281" mass="31042" checksum="6773FA735860492E" modified="2018-07-18" version="1">MQDSLVYLNGVLTPLSEAKIPVLDRGFIFGDGIYEVIPVYARKMFRAEQHLARLFRSLAAIRITNPYTESAWINLIEQVINAHPADDQMVYLQVTRGVAKRTHAFPVDVTPTVFIMTNPLASPSMAARAKGVACISMEDKRWLHCEIKSISLLGNILAAQYAVENEATETIQFRDGFLTEASASNVWVVKDGVLTAPPKDNLILEGIRYGLIEEMCQDLQITLVARKITRSEVFAADEILLSSATKEVLPVVSIDGNIIGTGQPGPIYTALYTAYQIAKKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0C5</accession>
    <name>A0A2S9H0C5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative metal-dependent hydrolases with the TIM-barrel fold</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1818</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93431">
        <property type="protein sequence ID" value="PRC93431"/>
        <property type="gene ID" value="S2091_1818"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01310">
        <property type="entry name" value="TatD_DNAse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001130">
        <property type="entry name" value="TatD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012022">
        <property type="entry name" value="UCP005295"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42658">
        <property type="entry name" value="PTHR42658"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01026">
        <property type="entry name" value="TatD_DNase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="343" mass="38127" checksum="136858A0D7DB1415" modified="2018-07-18" version="1">MTKINDITCPCCNGTLSAEMLEQILSQAGQFNAPAKLPMHGSNMLIDPHAHMIARTTDDYEAMARAGIVAVIEPAFWLGQLRTNVGSFIDYFSTISGFERFRAGQFGIRHYCCIGLNPKEANNPALAEEVLAILPRFLCKEGVVALGEIGYDERTPLEDHAFRAQIAMAKEFELPIMVHTPHRDKKRGTQYSMDVLEECGFDPARCVIDHNNEETVAEVLDRGYWCAFTIYPSTKMGNERLAKLVAQYGPERLIVNSACDWGVSDPLAVPKSARVMADHGISAAAIHQVVYQNALAVYGLNGEMRESHWTTPATIDQRHLYDGNSVLRGQEPRVDESNRDIIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0G2</accession>
    <name>A0A2S9H0G2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1835</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93448">
        <property type="protein sequence ID" value="PRC93448"/>
        <property type="gene ID" value="S2091_1835"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008727">
        <property type="entry name" value="PAAR_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05488">
        <property type="entry name" value="PAAR_motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="99" mass="9702" checksum="1C0803CE2A99FB1C" modified="2018-07-18" version="1">MPPASRITDMHVCPMVTPGVPPIPHVGGPISGPCVPNVLIGSLPAAVVGDMCVCVGPPDTIVKGSATVLISGRPAARIGDSTAHGGSIVLGFPTVMIGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0I5</accession>
    <name>A0A2S9H0I5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glutathione S-transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_1882</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GST superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93495">
        <property type="protein sequence ID" value="PRC93495"/>
        <property type="gene ID" value="S2091_1882"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00043">
        <property type="entry name" value="GST_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02798">
        <property type="entry name" value="GST_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="SSF47616"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GST N-terminal" evidence="2">
        <location>
            <begin position="6"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="3">
        <location>
            <begin position="95"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC93495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="230" mass="26060" checksum="1C43D32A843509E1" modified="2018-07-18" version="1">MKTYMSKMRLYSGPLSMFGAKVEIAAYEKGLDFELVMVPFNNKDGYSPKHLDVVRVNPKQQVPILIDGDLEIFDSTQIFEYLEDLKPSPALWPADPIARAHARQIEHKSDEVYFPHIIWLMGLQDSPNDPVAIASRIGAARFYREMEDALGKGDFLGGTYSYADIAFYMAQLFGARMGAEMTEETPKLIQWRIRMTSKPAVRKVVSPMVAYLISTGRQIPVFLNEFVPAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0V3</accession>
    <name>A0A2S9H0V3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1584</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93583">
        <property type="protein sequence ID" value="PRC93583"/>
        <property type="gene ID" value="S2091_1584"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="329"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="364"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="386"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="401"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="468"/>
            <end position="491"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="491" mass="54231" checksum="E9FFAC0B58C0769B" modified="2018-07-18" version="1">MLDAELYYPFLEKNLKKLIIGTAVLLSGCVVEPAHMYVQQSPQYPQYAQPSYAPAEVVYQAPAPQPVVSVYVEPPQYQPAPVLVAWAPPPMLVESPPMMPYDGAIWTGGYWVWEGNWVWAHGRWAPPPHPGYGWINPYYENRGGSVVFVNGFWAAPGVAFVAPPMGINIAIGIVAVGIIAGPRPMGPEGVFVPPPPGSHFGLIVPAPIGTAPAVVTSAPPIIRQGMRITVNNNVNNSVTNNVKNVYNVTNVTNVTNVTVVAPAGTTANGQAFNNSVPAQPHLAAAMTPVVKAYAPQPASSKSIPAYVAGRQPVALPPPQVVHSEVSPAMVAPHPQQTQAAPSHPQPIAAPAVPQHVTPAPIPSEQEERYQQQRSNPAQPAANEQRNMEKLQEEKQQQEKQQQQQQEKQQQQQQQQQQQQRLQQEKQQQQQQQQQQQQQQQQQQQQQQQERLKEERQQSVGKPAQEVKPNKPAENRSKEEIEKQEREHERKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0X0</accession>
    <name>A0A2S9H0X0_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">YceI domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1636</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93635">
        <property type="protein sequence ID" value="PRC93635"/>
        <property type="gene ID" value="S2091_1636"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007372">
        <property type="entry name" value="Lipid/polyisoprenoid-bd_YceI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036761">
        <property type="entry name" value="TTHA0802/YceI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04264">
        <property type="entry name" value="YceI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00867">
        <property type="entry name" value="YceI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101874">
        <property type="entry name" value="SSF101874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015573189" description="YceI domain-containing protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="domain" description="YceI" evidence="2">
        <location>
            <begin position="22"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="188" mass="20558" checksum="FAA896AA3F3B076A" modified="2018-07-18" version="1">MKLSQLVALALIVAAPQAFSQTYNIDPNHTYPSFEADHFGLSTWRGKFDKTKGTVTLDKVAKTGSLDIIIDASSIDFGHAKMNEHAKTPDIFNVAKYPTITYKASNFKFDGEKPVAVMGELTLLGVTKPVTLTINKFKCIIHPMMKREVCGADASAEFNRTDFGLSAYSPPFAPEVKLAIQVEAIIAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H138</accession>
    <name>A0A2S9H138_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_1678</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93677">
        <property type="protein sequence ID" value="PRC93677"/>
        <property type="gene ID" value="S2091_1678"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PAS" evidence="5">
        <location>
            <begin position="9"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="6">
        <location>
            <begin position="86"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="5">
        <location>
            <begin position="137"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="6">
        <location>
            <begin position="227"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="4">
        <location>
            <begin position="413"/>
            <end position="635"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC93677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="646" mass="73074" checksum="66CFF512A4D927DF" modified="2018-07-18" version="1">MATYEHQWKEEQFRQIVEMAPYAIVLVNERGMIEMVNRQAEKIFGYHREELLKQSLEMLLPERFRRQHTVDRNAFFSQPQPRAMSERGELFGRRKNGTEFPLEIGLNPIPTDEGSKVIATIVDISERVQHQQKLYELTELQQAIFDSTNFSIICTDSNGLFQIFNHSAERLLGYSAEEMVGKQTPVILHDMLEIIERAKQLTEELGTPIETGFETFVIKTRLLRTPDVNEWTYIHKDGSRIPVLLSVTALSDKRGDVSGYVAIAIDLREQKWQLSRIQDSEELFRVLYESSGDAHMLTTPEKGFVGANLAAAKLFGYSTINEFTAQSPATVSPEFQKDKRHSSEKALEMMQLALKNGSHKFEWLHKRADNSEFDAEVMLTSIKMGGKTMLEATVRDITERNRAERIKNEFISTVSHELRTPLTSISGVLSLVGQGVLGEISEQAKPMIQMAHRNSMRLSELINDLLDIEKLEAGETTFNFKMYGLMALINQSIDAISNFASQFNVTFNIIAQEDVQVFVDDGRLIQVLNNFLSNAAKFSPTGGHVDIAVRKIHSAEHSTVRVEIIDHGAGIPTSFRNRLFNKFSQADASDTKKKSGTGLGLAISKELIERMSGVIGFYSSVGEGSCFYFELPLPSKEKIRYSMFDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H159</accession>
    <name>A0A2S9H159_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1726</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93725">
        <property type="protein sequence ID" value="PRC93725"/>
        <property type="gene ID" value="S2091_1726"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012963">
        <property type="entry name" value="DUF1700"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08006">
        <property type="entry name" value="DUF1700"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="78"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="109"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="204"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="246" mass="27117" checksum="7914677BBBC35077" modified="2018-07-18" version="1">MTKLEFIAAFKSACDTLPSELLEAALADYERQFTDQLLSGLSEQTIVERWGSPQHAALKLKLGTFNGNLKQAVSAEKVARVGLSGVGLILMDFFLLIPATLYFSLLSVFYALALVAYLTGIFVSASSLAGVSFIDIPAHRIPNFISMHGTTHLDLNDIEIVPTLISSADLPTKAMEERLLGFNHAHFLHDQGLHIATNLNKNTLWNGIGITLAGMLLMLCCFLATRFTFRMLRRFAAWHFSVLKNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H177</accession>
    <name>A0A2S9H177_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ABC-type branched-chain amino acid transport systems ATPase component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_1719</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93718">
        <property type="protein sequence ID" value="PRC93718"/>
        <property type="gene ID" value="S2091_1719"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-1278">Translocase</keyword>
    <feature type="domain" description="ABC transporter" evidence="7">
        <location>
            <begin position="3"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="35"/>
            <end position="42"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC93718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="234" mass="25756" checksum="BD3D1F1E6F5FC9CD" modified="2018-07-18" version="1">MILTLTDVHGFYGKSHILQSININVAAGEVVTLLGRNGAGKTTTLKSIVGVVPAQRGKIMFEGEDITCIPTHKIAERGVCLVPEHRGIFKLLTVEENLTMSAKRDSAWKLDDIYRIFPRLKERRNNGGGHLSGGEQQMLAIGRALMTHPKILMLDEPVEGLAPVIVDEIVAQLKLINATGMTILLIEQNLEVCTQLADRHYIIEQGRVVHCASNQEFLNDDAVKDRYLGVNLAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1A4</accession>
    <name>A0A2S9H1A4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">PEP-CTERM protein-sorting domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1731</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93730">
        <property type="protein sequence ID" value="PRC93730"/>
        <property type="gene ID" value="S2091_1731"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013424">
        <property type="entry name" value="PEP_exosort_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07589">
        <property type="entry name" value="PEP-CTERM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02595">
        <property type="entry name" value="PEP_exosort"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015524219" evidence="1">
        <location>
            <begin position="24"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="domain" description="PEP-CTERM" evidence="2">
        <location>
            <begin position="243"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="272" mass="28172" checksum="2A4D17AFAFEA8F38" modified="2018-07-18" version="1">MSNFFLKSAAIVGLSALACSAYANPYLPGLTNLDFSSYSGTAPKGYFTNVDPTGWTGGTGLIFIDSTTPGQDAAGPVYLPTYGDPSPNLPGNYVEADGNPTYGSGFNYSVSGLTPGDNYTLIFYQAASQQTGFGNGLNTTERWIVSLGTAGMVYCNGCGAADSYYGGNDSTYSNADGSASVVATPLMTTPSGGTTPWQQVTLNLQADSTTDLLSFLAWGDNGNTVNLPPIVFLTGVDTPNEVPAPEPAALTLLGVGLLAIMLRRRSKQDGAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1G1</accession>
    <name>A0A2S9H1G1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_1428</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93819">
        <property type="protein sequence ID" value="PRC93819"/>
        <property type="gene ID" value="S2091_1428"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="3"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="5">
        <location>
            <begin position="128"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="128"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC93819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="229" mass="25847" checksum="15694F3A75315C73" modified="2018-07-18" version="1">MFRVMLIEDDPKLALLVSDYLARYEFSVVVVERGDQALAQFNECEPDIVILDLMLPGLDGMVVCSQIRQVSKVPILILTAREDAFDEVSGLEQGADDYVNKPVQPRVLLARLRALLRRVQDNPTVADIDALGFGALHISKSNRTIHWRDQPVTLNSAEYKLFILLAESAGQVLSRNDILVKMRGIEFDGLNRSIDNIISRLRRKFDDADSEKIKTVRSEGYLFSPSAWN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1M4</accession>
    <name>A0A2S9H1M4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Bacterial type III secretion apparatus protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1488</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93879">
        <property type="protein sequence ID" value="PRC93879"/>
        <property type="gene ID" value="S2091_1488"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013388">
        <property type="entry name" value="T3SS_OrgA/MxiK"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09482">
        <property type="entry name" value="OrgA_MxiK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="200" mass="22796" checksum="57649F022B8C39E2" modified="2018-07-18" version="1">MKKRINVKGEAWLAQIIFDPLSYVHPRRLRLPVSLDTPRQRAIVNRMLLGDLAEMSNRIEMAQQQLLRHWRDLPYICTLIGAQLMRQDLAWRGRLLTLPAPVLFFMSLPIRQAIGVTSEMSALPARCGSADVLHQVQGAGVSCILDWQMKAPSALLERMRLMFPPELDGHFESARKPPRASELFLILQAIQYAKNHPNLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1Q2</accession>
    <name>A0A2S9H1Q2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1489</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93880">
        <property type="protein sequence ID" value="PRC93880"/>
        <property type="gene ID" value="S2091_1489"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="240" mass="26352" checksum="0BDF028118445578" modified="2018-07-18" version="1">MPKIIQTLCNVVPDEGVLVRSAYLRNNIKASALVAEARRRARSLVMQADDEAARSYREAKSEGYAAGILLAADALAGYLAGHAALAVQLQVQLQQQVGTLLERSVSNSDVVMAAFEECLSEQDLSAVHGLDLLLPDSMRARHQDLIERLQKHVHGQVNIEYQNDARFLLRLGDHVAEFAPDDFIARAGVRAMRNLSSIHAASSELSDQCRQRLAMLFSSSSESDRASGDQVERIFSEVHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1U0</accession>
    <name>A0A2S9H1U0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1127</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC93954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93954">
        <property type="protein sequence ID" value="PRC93954"/>
        <property type="gene ID" value="S2091_1127"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="80" mass="8758" checksum="0EF008A572F53C87" modified="2018-07-18" version="1">MLQEANASCNSQRSALPIAQEDSGIVSLVIIAQLVGRRDDSLKPSDILSVTRQLENAKTRNVNMLSMSCPRCKAIQFPLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1V5</accession>
    <name>A0A2S9H1V5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_1144</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GtrA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC93971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93971">
        <property type="protein sequence ID" value="PRC93971"/>
        <property type="gene ID" value="S2091_1144"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000271">
        <property type="term" value="P:polysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007267">
        <property type="entry name" value="GtrA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04138">
        <property type="entry name" value="GtrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="37"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="69"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="100"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="domain" description="GtrA" evidence="7">
        <location>
            <begin position="9"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC93971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="134" mass="14507" checksum="254FEAB84D9E7BB7" modified="2018-07-18" version="1">MIKRELGIFLIVGSLTVLVDFGAYRSLVWLEVAGVDMAKAIGFLAGTVFAYFANRFWTFGHKSHASGSLWRFVILYGITLGANVLVNSLALKLFADATDAVHLAFLLATGVSATLNFLGMKLFVFKPRATSGLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H242</accession>
    <name>A0A2S9H242_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Cytochrome C oxidase, cbb3-type, subunit III</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">S2091_1109</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
        </cofactor>
        <text evidence="8">Binds 3 heme c groups covalently per subunit.</text>
    </comment>
    <comment type="PTM">
        <text evidence="9">Binds 3 heme groups per subunit.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC93936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93936">
        <property type="protein sequence ID" value="PRC93936"/>
        <property type="gene ID" value="S2091_1109"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014353">
        <property type="entry name" value="Membr-bd_ADH_cyt_c"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00034">
        <property type="entry name" value="Cytochrom_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13442">
        <property type="entry name" value="Cytochrome_CBB3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000018">
        <property type="entry name" value="Mb_ADH_cyt_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="2 8 10" id="KW-0349">Heme</keyword>
    <keyword evidence="6 9 10" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 9 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 11" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015691022" evidence="11">
        <location>
            <begin position="26"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="12">
        <location>
            <begin position="36"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="12">
        <location>
            <begin position="180"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="12">
        <location>
            <begin position="302"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="binding site" description="covalent" evidence="8">
        <location>
            <position position="50"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="8">
        <location>
            <position position="53"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="9">
        <location>
            <position position="54"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="covalent" evidence="8">
        <location>
            <position position="195"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="8">
        <location>
            <position position="198"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="9">
        <location>
            <position position="199"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>2</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="covalent" evidence="8">
        <location>
            <position position="315"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="8">
        <location>
            <position position="318"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="9">
        <location>
            <position position="319"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>3</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000018-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000018-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PRC93936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="414" mass="44173" checksum="E10E320D7C3C36C0" modified="2018-07-18" version="1">MKKVLTGLVLLALMALVGCDGSIGATDKTIQPDHKAQIEFGRYLTKAADCAACHTTSTGAPFAGGVELASPFGKFYGSNITPDKEHGIGKWSADQFYKALHDGVTPDKHLYPAMPYTSYRGMTRADSDAIYAFLMQQKAVAVATRPADLKFPYNMRFGMMFWNVLFLKNSLNDASVGQSASWQRGQYLSNVMGHCAECHTPRGLFGQLDLSKSLTGAALARVAAPNVTPAGLAAVGWNPADLQTFLASGIAPQGSAYGDMFPVVHLSTQYLSKDDLVAVTTYLFGDKPLVPEPVKAIALDTAELKAGQRLYTAVCAGCHGFQGEGKPHVAVPMQGNSTVRNADSHNLIVTILDGVEAQKFPGIENLQEMPGFATTLSDQELAQLTNFLRAQWGGHAASVTPEQVKGLKLAAGTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H287</accession>
    <name>A0A2S9H287_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">2-enoyl-CoA Hydratase C-terminal region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1251</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94078">
        <property type="protein sequence ID" value="PRC94078"/>
        <property type="gene ID" value="S2091_1251"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003860">
        <property type="term" value="F:3-hydroxyisobutyryl-CoA hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045004">
        <property type="entry name" value="ECH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032259">
        <property type="entry name" value="HIBYL-CoA-H"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43176">
        <property type="entry name" value="PTHR43176"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16113">
        <property type="entry name" value="ECH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ECH_2" evidence="2">
        <location>
            <begin position="18"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="390" mass="41786" checksum="737C9CA454B06394" modified="2018-07-18" version="1">MSAPVLFEERSAANGMRIGIATLNAEKSLNALSLEMVHLLTERLAAWSVDTGIAFVVLQAAGEKAFCAGGDLQNLYRAMRAHHSSAERDDVSANAYAMEFFADEYRLDYLIHTFPKPVLCWGDGVVMGGGVGLMAGASHRVVTEQTRVAMPEISIGLFPDVGGSWLLSRMPGKIGLFLALTATQVRAADALFVGLADYALVRSNKDAVFAALLQQSWNKFADDNHSFLSQVLRQFADPTLAEAGMLQQNFAAINALCDRTSVAEIAAEIHAAAGTSPWLAKAAATLAGGSPGSAQLSMVLQQCAASKPLADVFRMEYIVALHCAARPDFAEGIRALLIDKDGSPRWQPASLEQVSHTWLEGFFAEPAWAAHPLKNLEHTSPSAPIYGAEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H292</accession>
    <name>A0A2S9H292_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Acyl-CoA dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_1253</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94080">
        <property type="protein sequence ID" value="PRC94080"/>
        <property type="gene ID" value="S2091_1253"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003995">
        <property type="term" value="F:acyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006089">
        <property type="entry name" value="Acyl-CoA_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="SSF47203"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="SSF56645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00072">
        <property type="entry name" value="ACYL_COA_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00073">
        <property type="entry name" value="ACYL_COA_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA_dh_N" evidence="7">
        <location>
            <begin position="6"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_M" evidence="6">
        <location>
            <begin position="121"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_1" evidence="5">
        <location>
            <begin position="227"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC94080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="386" mass="41775" checksum="BF6ACEE748E8FC64" modified="2018-07-18" version="1">MDFELTQEQLAFQQSARDFAAGELAPHAAEWDANCTFPIDALRHAGELGFCGIYSPEEEGGLGLSRLDAAIIFEELAAVDPSTTAYLTIHNMATWMLCEWGTEELRKRWGKRLTSGREFASYCLTEAGSGSDAASLKTRAEPVANGYVLNGSKAFISGAGVSALLVVMARTGGSGATGISAFAVPADTPGISFGRKEEKMGWNSQPTRSVFFENVRIPADHLLGDLGDGFRIAMRGLDGGRINIATCSVGAAQGALNAAQIYVKERKQFGRALADFQSVQFKLADMLTDLVAARHMVRLAATKLDAKAPHATAYCAMAKRLATDIGFQICNDALQIHGGNGYIREYPLERLVRDTRAHQILEGTNEIMRSIIARKFLETIMIGDIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2B3</accession>
    <name>A0A2S9H2B3_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7">30S ribosomal protein S11</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rpsK</name>
        <name evidence="9" type="ORF">S2091_1292</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7 8">Belongs to the universal ribosomal protein uS11 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94119">
        <property type="protein sequence ID" value="PRC94119"/>
        <property type="gene ID" value="S2091_1292"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01310">
        <property type="entry name" value="Ribosomal_S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001971">
        <property type="entry name" value="Ribosomal_S11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019981">
        <property type="entry name" value="Ribosomal_S11_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018102">
        <property type="entry name" value="Ribosomal_S11_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036967">
        <property type="entry name" value="Ribosomal_S11_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11759">
        <property type="entry name" value="PTHR11759"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00411">
        <property type="entry name" value="Ribosomal_S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002131">
        <property type="entry name" value="Ribosomal_S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03632">
        <property type="entry name" value="uS11_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00054">
        <property type="entry name" value="RIBOSOMAL_S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7 8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 7 8" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 7" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00015692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC94119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="134" mass="14025" checksum="F26B0C1270AFFE01" modified="2018-07-18" version="1">MAKAPNNAAAARARKKVKKNVAEGIAHVHASFNNTIITITDRQGNALSWATAGGAGFKGSRKSTPFAAQVAAEAAGKVAVECGVKNLEVRIKGPGPGRESSVRALNNLGIKISLIQDVTPVPHNGCRPPKRRRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2C0</accession>
    <name>A0A2S9H2C0_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Histidinol-phosphate aminotransferase</fullName>
            <ecNumber evidence="6">2.6.1.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Imidazole acetol-phosphate transaminase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">hisC</name>
        <name evidence="8" type="ORF">S2091_1179</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>2-oxoglutarate + L-histidinol phosphate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:23744"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57766"/>
            <dbReference type="ChEBI" id="CHEBI:57980"/>
            <dbReference type="EC" id="2.6.1.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 6">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 6">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 7/9.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 6">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.9" evidence="6"/>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94006">
        <property type="protein sequence ID" value="PRC94006"/>
        <property type="gene ID" value="S2091_1179"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00012"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004400">
        <property type="term" value="F:histidinol-phosphate transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01023">
        <property type="entry name" value="HisC_aminotrans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005861">
        <property type="entry name" value="HisP_aminotrans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01141">
        <property type="entry name" value="hisC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5 6" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="6" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="6" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="7">
        <location>
            <begin position="25"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="6">
        <location>
            <position position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC94006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="357" mass="39223" checksum="1A413417A4C92BB4" modified="2018-07-18" version="1">MSLIKNIIRPEILAQSSYHVPDAANMVKLDAMENPYGLPDAIKAKLGAHLSEVALNRYPIPSYRVLKQKICQQFGVPTGFDVILGNGSDELISMLSVACAKPGAKVLAPVPTFVMYAISAQLAGVEFVGVPLQADLTLDLPAMLVAIKQHRPALLYLANPNNPTGTWFDDAQIIQIIHAMAEIGLVVVDEAYQPFAPGSMMSRLPEFENLIVMRTVSKLGLAGLRLGYMSAAPALLAEIEKVRPPYNVNVLTVAALEFLLDHMSLFNEQAEQICKQRSVLISTLQKLHQIHVFPSQANFVLIRVSNSEQIFNKLLEHKILVKNVGKMHQLLVDCLRVTVSTPAENQLFMDALIATLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2C1</accession>
    <name>A0A2S9H2C1_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6">30S ribosomal protein S14</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rpsN</name>
        <name evidence="7" type="ORF">S2091_1302</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 6">Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the universal ribosomal protein uS14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94129">
        <property type="protein sequence ID" value="PRC94129"/>
        <property type="gene ID" value="S2091_1302"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00537">
        <property type="entry name" value="Ribosomal_S14_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001209">
        <property type="entry name" value="Ribosomal_S14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023036">
        <property type="entry name" value="Ribosomal_S14_bac/plastid"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19836">
        <property type="entry name" value="PTHR19836"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00253">
        <property type="entry name" value="Ribosomal_S14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 6 7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00537"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC94129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="101" mass="11538" checksum="912CD2DB832401BC" modified="2018-07-18" version="1">MAKLALINREQKRADLVKKFAGKRAALKAIVDDQSKTEEERYDARLKLQALPRNSNPTRQRNRCALTGRPRGTFRKFGLGRIKLREVAMRGEVPGMTKASW</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2N2</accession>
    <name>A0A2S9H2N2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0838</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94217">
        <property type="protein sequence ID" value="PRC94217"/>
        <property type="gene ID" value="S2091_0838"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="72" mass="7572" checksum="1F6771273431CFFB" modified="2018-07-18" version="1">MPPWAAIAPYGTLFGLVFITSILLLRGVQLSTVAITDGGVSFAPLTSLGIALAATLLILIPRKFSTKNKQTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2N6</accession>
    <name>A0A2S9H2N6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0824</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94203">
        <property type="protein sequence ID" value="PRC94203"/>
        <property type="gene ID" value="S2091_0824"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="119" mass="12321" checksum="A1FB5CFFF9C0809C" modified="2018-07-18" version="1">MNINSKSNQAIAINAVHDNARLAKYVLAGAVLVCAGITTCHAANSGVITFMGSIATNSCSLSSGNVPQLSKCEAHVAASTKVTSSTLTPVKVTETIHTDTVKNSDGQTVPRKIIFANYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2T5</accession>
    <name>A0A2S9H2T5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0912</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94291">
        <property type="protein sequence ID" value="PRC94291"/>
        <property type="gene ID" value="S2091_0912"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015630999" evidence="2">
        <location>
            <begin position="30"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="104"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="236"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="177"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="321" mass="30913" checksum="4ECF76C53E20B5EF" modified="2018-07-18" version="1">MKSTMIKSTLSLAIIGLFAAGCTSTPPHVAENNYVQQPAPISYVGPPGATGATGAQGIQGETGATGPTGLAMAGPTGATGETGAQGMQGPVGETGVEGRMVVGRAGPTGATGATGAQGMTGDTGAQGSSIPGPAGATGATGLTGIQGVIGSRGPEGPSREGPAGPAGAVGATGAQGLVGSTGAQGNTETAGLSGPTGATGSTGPQGEVGQTGAQGMGGSTGALGYTGTGAQGNSTPSWNYTFKGNSDDTQKSDDGKTQEIVSYMNQNPSSQITINGPSNRYVHSVIESLTDAGVKESRIHLGPLTDSTQDNGHRVDVIISN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2U7</accession>
    <name>A0A2S9H2U7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="12">TonB family C-terminal domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">S2091_0930</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
            <orientation evidence="1">Periplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TonB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94309">
        <property type="protein sequence ID" value="PRC94309"/>
        <property type="gene ID" value="S2091_0930"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006260">
        <property type="entry name" value="TonB/TolA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037682">
        <property type="entry name" value="TonB_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03544">
        <property type="entry name" value="TonB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01352">
        <property type="entry name" value="tonB_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="15"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_C" evidence="11">
        <location>
            <begin position="134"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="54"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF03544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PRC94309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="213" mass="22920" checksum="538CEC5022A0A840" modified="2018-07-18" version="1">MNFSEREQDPIKKMTGIFVVVVIHAIVIYALLTGLGKQIIAVIKELPIETTIIEEVKPPPPPPETPPPPPKLVEPPPPFIPVPEIQVDQPVSPNAIAATTNVQPQPSDATEVATTSTTGPSVVKAQVDFSTCDKPAYPTNSLRNEEAGVVRIQFLIGLDGRVADSKIEKSSGFKTLDVAAKKALGLCKFKPGTVDGKPQQLWTAVEYAWKLPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2W9</accession>
    <name>A0A2S9H2W9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0950</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94329">
        <property type="protein sequence ID" value="PRC94329"/>
        <property type="gene ID" value="S2091_0950"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025528">
        <property type="entry name" value="BrnA_antitoxin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14384">
        <property type="entry name" value="BrnA_antitoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="98" mass="11158" checksum="E2E8EAEA744624CD" modified="2018-07-18" version="1">MNKRNKAVIDPEMRDFEDALLRSMDQAKKGEYAAVHTPEQIVARRGRPVGSVKADAKQAVKLRFDPDVLAALRSTGRGWQTRVNEVMREWVKTHAKNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2Z0</accession>
    <name>A0A2S9H2Z0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Response regulator containing a CheY-like receiver domain and an HD-GYP domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_0965</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94344">
        <property type="protein sequence ID" value="PRC94344"/>
        <property type="gene ID" value="S2091_0965"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008081">
        <property type="term" value="F:phosphoric diester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037522">
        <property type="entry name" value="HD_GYP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01966">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51832">
        <property type="entry name" value="HD_GYP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="5"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="HD-GYP" evidence="3">
        <location>
            <begin position="128"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC94344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="346" mass="38099" checksum="613A57C729267759" modified="2018-07-18" version="1">MSLQTILIVDDEPANLAIMEDALADSYKLAFARNGRETLAAVAKHCPAMVLLDIGLPDINGYDLCRQIKKIDSTGSVQVIFVTAYTDTAHEEAGFDAGGVDYLIKPVSTPIVRARVATHLSLVRATLLEKSYRDAILMLGQAGHFNDTDTGAHIWRMAAYARALAQGYGWSEENSERLELAAPMHDTGKIGIPQGILRKPGPLDEQEWVVMRTHPQIGYNILSKSDAPVFQLAAEVALRHHEKWDGSGYPDGLRRKDIPESARIVALADVFDALSMRRPYKEPWPIEKILGYVNASSGQHFDPKLVDVFSKILPQLLDIQSKWASAEDKSILNQSSTTNGTDAKLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H355</accession>
    <name>A0A2S9H355_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">YcaO domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1035</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94414">
        <property type="protein sequence ID" value="PRC94414"/>
        <property type="gene ID" value="S2091_1035"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003718">
        <property type="entry name" value="OsmC/Ohr_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036102">
        <property type="entry name" value="OsmC/Ohrsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003776">
        <property type="entry name" value="YcaO-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041080">
        <property type="entry name" value="YcaO_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019938">
        <property type="entry name" value="YcaO_dom_prot"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02566">
        <property type="entry name" value="OsmC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02624">
        <property type="entry name" value="YcaO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18381">
        <property type="entry name" value="YcaO_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82784">
        <property type="entry name" value="SSF82784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00702">
        <property type="entry name" value="TIGR00702"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03549">
        <property type="entry name" value="TIGR03549"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51664">
        <property type="entry name" value="YCAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YcaO" evidence="1">
        <location>
            <begin position="206"/>
            <end position="594"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="737" mass="81919" checksum="E1ED23ECC54AFFB5" modified="2018-07-18" version="1">MEIKVNFLDKLRIEAKFDDFTVIADQPIRYKGDGSAPGPFDYFLASSALCAAYFVKLYCDTRNISTENIRLSQNNIVDPENRYQQIFKIQVELPADISAKDRQGILRSIDRCTVKKVVQAGPEFVIEEVENLDADAQALLTLSSTADAATYIAGKDLPLEQTIANMSALLAGLGIKIEIASWRNIIPNVWSLHIRDAHSPMCFTNGKGATKESALASALGEYIERLSCNHFYAGSFWGEDIANAAFVHYPNERWFKPGKKDALPAEILDEYCLDIYNPDGELRGSHLIDTNSGNAARGICSLPYVRQSDSEVVYFPSNLIENLFVSNGMSAGNTLAEAQVQCLSEIFERAVKREILEGEIALPDVPQEVLEKFPGILAGIQSLEEQGFPVLVKDASLGGQYPVMCVTLMNPRTGGVFASFGAHPSLEVALERSLTELLQGRSFEGLNDLPQPTFVSNAVTEPNNFVEHFIDSSGVVSWRFFSAKADYDFVEWDFSGQGENSNAEEAATLFGILEAMGKEVYMAVYDQLGATACRILVPGYSEVYPAEDLIWDNTNKALLFRTDILNLHQLNDASLEALLDRLENNELDDYSDVATLIGIEFDENTVWGQLTVLELKLLIQLALEQFEDAHELVGTFLQYNDNTVERGLFYQALNVVLEVLLDDDLELDDFVVNFRRMFGNPRMDAVLGSVDGSVRFFGLTPTSMKLEGLDRHQRLIDSYKKLHTARAKVTASSSDFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3K4</accession>
    <name>A0A2S9H3K4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative GTPases (G3E family)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_1067</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SIMIBI class G3E GTPase family. CobW subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94446">
        <property type="protein sequence ID" value="PRC94446"/>
        <property type="gene ID" value="S2091_1067"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1220.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011629">
        <property type="entry name" value="Cbl_biosynth_CobW-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036627">
        <property type="entry name" value="CobW-likC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003495">
        <property type="entry name" value="CobW/HypB/UreG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02492">
        <property type="entry name" value="cobW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07683">
        <property type="entry name" value="CobW_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00833">
        <property type="entry name" value="CobW_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CobW C-terminal" evidence="3">
        <location>
            <begin position="256"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="219"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC94446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="351" mass="39236" checksum="B71FD407DFE7ADDF" modified="2018-07-18" version="1">MKLIPSTILTGFLGAGKTTLLNRILHEDHGFKIAVIENEFGAENIDNEILHRDTKEQIIEMNNGCICCTVRGDLIVALSNLAEKRNAGEISFDHLIIETTGLANPGPVAQTFFVDDQVASHYMLDAIITVVDAKHAMQQLDQHQEAQRQVGFADKLFISKADLVTATDLDSLTARLKRINPRAPITTAHFGQVAIADVLDLRGFNLNDKLAIDPDFMGETEEEHHHHDDAEHCEHEDHSHCDHHDHDHAHQHLDDISAFVFKSQRPFNTALLDEYLSGIITAFGPQMLRYKGILFMDGADCKVVFQGVHQIMGSDVGRPWEKDEIKESKIVFIGNNLPKDIFISGLEQCLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3R3</accession>
    <name>A0A2S9H3R3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Plasmid stabilization system protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0613</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94610">
        <property type="protein sequence ID" value="PRC94610"/>
        <property type="gene ID" value="S2091_0613"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2310.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007712">
        <property type="entry name" value="RelE/ParE_toxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035093">
        <property type="entry name" value="RelE/ParE_toxin_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05016">
        <property type="entry name" value="ParE_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-1277">Toxin-antitoxin system</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="97" mass="11264" checksum="FBC4BA7B7BD683B4" modified="2018-07-18" version="1">MELIWTPHARQARTAAIDYIAKDSPHAALAQLNEIERQTDMLIDYPEMERLGRVDGTRELVISNTSFVAIYRLNLPANRIELFRFVHSSQRWPATVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H413</accession>
    <name>A0A2S9H413_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Dehydrogenases with different specificities (Related to short-chain alcohol dehydrogenases)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0713</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94710">
        <property type="protein sequence ID" value="PRC94710"/>
        <property type="gene ID" value="S2091_0713"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="247" mass="25930" checksum="921303467101C386" modified="2018-07-18" version="1">MNTNKKTVIITGASSGIGFALAEEYLKRGYNVVGNARTSERLKAAAEKLGKPDNFLLVAGDISKPETAKEIFDRAIAKFTKVDILINNAGIFIAKPITAYTEEDLDSIVSTNLKGFFHPTQLAAAHMSANKQGHIVTITASIAMQPSAKVPALLPVLIKGGLNHATRALAIELATSNVKVTAVAPGMIDTPLHSNDEGTKAFLKTMAPSAQIGATKDIVDAVLYLTEAQFTTGVVLAVDGGATAGNW</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4E8</accession>
    <name>A0A2S9H4E8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Arginine N-succinyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0006</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94811">
        <property type="protein sequence ID" value="PRC94811"/>
        <property type="gene ID" value="S2091_0006"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008791">
        <property type="term" value="F:arginine N-succinyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006527">
        <property type="term" value="P:arginine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007041">
        <property type="entry name" value="Arg_succinylTrfase_AstA/AruG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017650">
        <property type="entry name" value="Arginine_N-succinylTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04958">
        <property type="entry name" value="AstA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03243">
        <property type="entry name" value="arg_catab_AOST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03244">
        <property type="entry name" value="arg_catab_AstA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="361" mass="40524" checksum="1122F633BDAED1A6" modified="2018-07-18" version="1">MIVVRAIKKDDLDGLMYLATQVGDGMTTLKPDTEMLSNRIAVACASFAEQIPPEQRDYLFVLEDTDNGKIIGVSAIKSAVGLDEPFYNYRIGTLVHSSKELNVYSRMDTLYLSNDLTGCAELCSLFLHPDYRNNNNGRLLSKCRFLFIAQFPHLFSEKLIAELRGFQYPDGSSPFWDNLGRHFFKMDFNRADDISSLGKKSFIAELMPRHPLYVAYLPKVAQDVIGQVHVDTAPARRLLEQEGLYYEGFVDIFDAGPVLQARVNELRSVRLSELLEVVDCSAALLSDPAAAEPMLVANTSIQDYRIIVSDLLPHHGQLQLTLEQQQVLGCSVKSQVRAMPLNAKNEAKNEVRKIGENYNEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4X1</accession>
    <name>A0A2S9H4X1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0224</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95029">
        <property type="protein sequence ID" value="PRC95029"/>
        <property type="gene ID" value="S2091_0224"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC95029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="353" mass="39699" checksum="45991C2A58CEB684" modified="2018-07-18" version="1">MEMHISHHQSTPPLSLLETLADSSAQHVHDILSIALQHNKTHSAVVVFDQRCELAQILCAAYQRCLPNARFINFDTVTPEFVLEAFAPLVAADLVVLIQSTNFRLEAFRIRVELFKRQLKVIEHPHLARMNDEQIPYYVASLAYDPNYYRTVGRALKQRIDQAQHGMVDSGEGAQLIFGSAFEAAKLNIGDYSEMTNIGGQFPIGEVFTEAQDLEAVHGRVRIFVFGDTSFTVNQPEHPITLIINKGRVTDVENSTPEFDLVLQQIREAEGEIWLRELGFGMNRAFSAERTVSDIGTYERMCGIHLSLGAKHGVYTKPQIRRAEAKYHVDVFAATVTVSLDDAVIYRDGAWQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4Y1</accession>
    <name>A0A2S9H4Y1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HDIG: uncharacterized domain HDIG</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0234</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95039">
        <property type="protein sequence ID" value="PRC95039"/>
        <property type="gene ID" value="S2091_0234"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006675">
        <property type="entry name" value="HDIG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013976">
        <property type="entry name" value="HDOD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08668">
        <property type="entry name" value="HDOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00277">
        <property type="entry name" value="HDIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51833">
        <property type="entry name" value="HDOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HDOD" evidence="1">
        <location>
            <begin position="27"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC95039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="287" mass="31875" checksum="1F80FF047C4BDD1C" modified="2018-07-18" version="1">MTTTVNNSEFEFIQGLTADLSAPVLIFPTSLKTTMNIRHAIIQDNISNDNLARIISTEPVLSAQVLKLSNSAAFNSTGKVTTELRKATMRLGFAKVRNLTIAVGMKQLAAHQDVNGEISVLMEGLWSRSLRVAALSHVIAQNLTKVNPDDAMLAGLLHDVGKFYILNRAKHYQSLFTSHQALWNVVDDWHSNIGAAILENWEVSDDIRNAVQNFGNPKYEHLGALDLTDVIVAADILDAHFDDRSKRKLNWDELPTVLLHLELDAEKSEQLRESTKIELDQLLGSIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H515</accession>
    <name>A0A2S9H515_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0218</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95023">
        <property type="protein sequence ID" value="PRC95023"/>
        <property type="gene ID" value="S2091_0218"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009732">
        <property type="entry name" value="DUF1304"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38446">
        <property type="entry name" value="PTHR38446"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06993">
        <property type="entry name" value="DUF1304"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="81"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="103"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC95023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="121" mass="13171" checksum="C58377FBF1DD7A53" modified="2018-07-18" version="1">MKTAIMLMVALVALEHVYFLVLEMFLWTKPKGRKIFGLTEQFAKDSQGLAANQGLYNGFLAAGLCWSLVHPDAHYADQLQLFFLGCVIVAAVFGAVTVKRSILFIQGIPAMLALALVLIGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H524</accession>
    <name>A0A2S9H524_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Efflux transporter, RND family, MFP subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_0279</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95084">
        <property type="protein sequence ID" value="PRC95084"/>
        <property type="gene ID" value="S2091_0279"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043602">
        <property type="entry name" value="CusB_dom_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006143">
        <property type="entry name" value="RND_pump_MFP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00529">
        <property type="entry name" value="CusB_dom_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01730">
        <property type="entry name" value="RND_mfp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HlyD_D23" evidence="3">
        <location>
            <begin position="79"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="domain" description="CusB_dom_1" evidence="2">
        <location>
            <begin position="313"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC95084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="386" mass="41264" checksum="939F2F44A007B857" modified="2018-07-18" version="1">MNSLSTPSSLSGFIIKTSLYAVLGTSIITGISGCDLVQATNSKETKLPDLIHEGGAVSVPETSPLRKTLLVAAVESLPFERPISAPGVVEADPTKLVKITPPLAGRIIKINKMLGDTVKTGDTLFTLDSAELSGAQSEAAKAHSQLQLAYKSLQRQQVLAAAEIIAHKDLEQSESDYEQAKSEAERTTAHLTQLGAKPGNSSQRTYDLRSPIAGRVIEMNGSQGAFWNDINESILTVADLSTVWMSASVSEQDIASVFVGQKATIILNAYTGQSFEGVVRYVGEVLDPDTRSIKVRVAIDNKDTKFLPGMFAKVVFSGQKHKALVVPPSALVQSGLYTRVFVEKAPFTYEPRVIKTGATLGSHIEVVSGLTAGERIVVKEGVLLND</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5D3</accession>
    <name>A0A2S9H5D3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">3-oxoacyl-(Acyl-carrier-protein) synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_0338</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95143">
        <property type="protein sequence ID" value="PRC95143"/>
        <property type="gene ID" value="S2091_0338"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00834">
        <property type="entry name" value="KAS_I_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000794">
        <property type="entry name" value="Beta-ketoacyl_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018201">
        <property type="entry name" value="Ketoacyl_synth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11712">
        <property type="entry name" value="PTHR11712"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00606">
        <property type="entry name" value="B_KETOACYL_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PKS_KS" evidence="3">
        <location>
            <begin position="9"/>
            <end position="414"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC95143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="414" mass="44111" checksum="26D5E626423A92C8" modified="2018-07-18" version="1">MTLQKNHRVVVTGMAGISPIGNDWKTIRERLGRYQNAIVNMPEWADYEGLNTQLGAPAVPFELSEKYNRKAIRSMGRIALMATRASELALLDAGLLDSPLIKSGQMGVSFGSSAGTPSAIGDFGRMMEERTTKGINATTYIKMMAHTAPVNIGVFFGLTGRVITTSSACTSGSQGIGYAYEAIRSGRQLAMIAGGAEELCATEAAVFDTLFATSVKNDAASTTPRPFDTNRDGLVIGEGAGSLILEEFEHAQARGATIYAELVGFATNSDGCHVTQPNSETMKIAMQLALADAGLQASDIGYVNAHGTGTEQGDIAESHATAQVFGKHTPISSLKSYMGHTLGACGALEAWISIEMMREGWFAPTVNLENVDPRCAELDYIVGSGRELQCDYVMSNNFAFGGINTSLIFKKVQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5E7</accession>
    <name>A0A2S9H5E7_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 12">D-alanine--D-alanine ligase</fullName>
            <ecNumber evidence="5 12">6.3.2.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">D-Ala-D-Ala ligase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">D-alanylalanine synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">ddl</name>
        <name evidence="16" type="ORF">S2091_0397</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 12">Cell wall formation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>ATP + 2 D-alanine = ADP + D-alanyl-D-alanine + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:11224"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57416"/>
            <dbReference type="ChEBI" id="CHEBI:57822"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="13">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="13">Binds 2 magnesium or manganese ions per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="12">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 12">Belongs to the D-alanine--D-alanine ligase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.4" evidence="5 12"/>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95202">
        <property type="protein sequence ID" value="PRC95202"/>
        <property type="gene ID" value="S2091_0397"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008716">
        <property type="term" value="F:D-alanine-D-alanine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00047">
        <property type="entry name" value="Dala_Dala_lig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000291">
        <property type="entry name" value="D-Ala_lig_Van_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005905">
        <property type="entry name" value="D_ala_D_ala"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011095">
        <property type="entry name" value="Dala_Dala_lig_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011127">
        <property type="entry name" value="Dala_Dala_lig_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07478">
        <property type="entry name" value="Dala_Dala_lig_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01820">
        <property type="entry name" value="Dala_Dala_lig_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039102">
        <property type="entry name" value="Ddl/VanB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="SSF52440"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01205">
        <property type="entry name" value="D_ala_D_alaTIGR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00843">
        <property type="entry name" value="DALA_DALA_LIGASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 12" id="KW-0133">Cell shape</keyword>
    <keyword evidence="11 12" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="12" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 12 16" id="KW-0436">Ligase</keyword>
    <keyword evidence="13" id="KW-0460">Magnesium</keyword>
    <keyword evidence="13" id="KW-0464">Manganese</keyword>
    <keyword evidence="13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10 12" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-grasp" evidence="15">
        <location>
            <begin position="116"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00003921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010871"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012216"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR039102-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="PRC95202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="330" mass="35256" checksum="5F0C4A6D34501EC9" modified="2018-07-18" version="1">MADTMTNVTINSAVQELGKVGVLFGGRSAEREVSIMSGTGVLSALQSLGVDAHAFDPGVQSLAELAEQKFDRVFIALHGRYGEDGTLQGALEQLGIPYTGSGVLASALAMDKAMTKRIWLASGLSTPKFAMLSGASDWAAIAQYLELPLIVKPAHEGSTMGLTKVTEVSQLPAAYALAARFDSAVIAEQFIEGIELTCAILGKDESAHALPLIRIAAPDANYDYQNKYFTDDTQYFCPSGLPEEQARAIQEMMVASYKVLGCRGWGRGDVMVRASDNKAFLLEMNTSPGMTGHSLVPMAARVAGLGYAELCLEILKMAELDLHVSADWKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5K3</accession>
    <name>A0A2S9H5K3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">AMP-binding enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0351</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95156">
        <property type="protein sequence ID" value="PRC95156"/>
        <property type="gene ID" value="S2091_0351"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-binding" evidence="1">
        <location>
            <begin position="137"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC95156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="598" mass="65609" checksum="C45177DB2C3E6D21" modified="2018-07-18" version="1">MSDSMLNLLQRMAANTSTSTIGWRNGAVVSSDDFIARVASWQTLLSPLSGQNFALYLEDSIEFAAALLGAWHAGKTIWLTADTLASSNNALKLSVDGFLGEFPADCAPLLLNAMPSTTPDSTAETALDYAALDAQFVGLVVHTSGTTGAAQAIPKKLSQLAIEVATLEQLFDARLADAEIISTVTHQHIYGLLFKVLWPLVSGRAIHARTVMFPEELAQLMSTRSCALISSPAHLKRLPMHLSWSGANSHLHAVFSSGGALPADVAQSSAALLGKMPIEIYGSSETGGIAWRQRRTEQDDVQDNSWQMLPNVEWRTSSDECLLEVRSPHLLSDAWHTLADRAQAHKNGGFILQGRADRIVKIEEKRISLDAIEQKLATSPLVAEVKVIVLSEQLNSNQRQHLAAVVVISELGKNLLLSAGKLAVNRQLKDLLVGIVEPVAIPRKWRYVDSFPINLQGKTPHAMLQALFENEAKAPEQAVLTPHYKIRHSDVNSVEFDVIWPPNLLYFSGHFPEAPVLPGVVQVDWAIKIGRQTFDLPTQFRAIHALKFQHVILPDSPVNLKLDFDQQKGCLSFSYFTSTWQHSSGRILFADAIHDDTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5K4</accession>
    <name>A0A2S9H5K4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Exodeoxyribonuclease III</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_0452</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA repair enzymes AP/ExoA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95257">
        <property type="protein sequence ID" value="PRC95257"/>
        <property type="gene ID" value="S2091_0452"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008853">
        <property type="term" value="F:exodeoxyribonuclease III activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09086">
        <property type="entry name" value="ExoIII-like_AP-endo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004808">
        <property type="entry name" value="AP_endonuc_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020848">
        <property type="entry name" value="AP_endonuclease_F1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037493">
        <property type="entry name" value="ExoIII-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43250">
        <property type="entry name" value="PTHR43250"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="SSF56219"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00633">
        <property type="entry name" value="xth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00728">
        <property type="entry name" value="AP_NUCLEASE_F1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51435">
        <property type="entry name" value="AP_NUCLEASE_F1_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Endo/exonuclease/phosphatase" evidence="3">
        <location>
            <begin position="6"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007092"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC95257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="254" mass="28992" checksum="E7A9B6ACB0B54508" modified="2018-07-18" version="1">MKLACWNVNSLKVRLPQVLQWLQDNPIDVLCLQETKLTDDKFPTTDIEAAGYHVVFSGQKTYNGVAILSRHPISDVVKNNPLFDDEQQRLLTVTIQGMRIICAYIPNGQAPDSDKYQYKLKWLAALQNWLIEQQKTYPELALLGDFNIAPEDRDVHDPAAWEGQNLVSEPERAAFQAMIALPLVDSYRLFEQADKSFSWWDYRALGFRLNKGMRIDHILLSTPLAARCQSCVIDRAPRKWEQPSDHAPVIATLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSB1</accession>
    <name>A0A2S9GSB1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4716</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000051">
        <property type="protein sequence ID" value="PRC90578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90578">
        <property type="protein sequence ID" value="PRC90578"/>
        <property type="gene ID" value="S2091_4716"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC90578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="62" mass="6307" checksum="9A0F3C19F4D18CBA" modified="2018-07-18" version="1">MLPDTVQIAVVAEVNVAASLALLVADTVNGAVPYDLPVNAANVIVWASLATTNDCATWVAAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSD6</accession>
    <name>A0A2S9GSD6_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Thiol:disulfide interchange protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_4663</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 4">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the thioredoxin family. DsbA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000042">
        <property type="protein sequence ID" value="PRC90627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90627">
        <property type="protein sequence ID" value="PRC90627"/>
        <property type="gene ID" value="S2091_4663"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03019">
        <property type="entry name" value="DsbA_DsbA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001853">
        <property type="entry name" value="DSBA-like_thioredoxin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023205">
        <property type="entry name" value="DsbA/DsbL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01323">
        <property type="entry name" value="DSBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001488">
        <property type="entry name" value="Tdi_protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3 4" id="KW-0574">Periplasm</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015785956" description="Thiol:disulfide interchange protein" evidence="6">
        <location>
            <begin position="23"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="7">
        <location>
            <begin position="11"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="5">
        <location>
            <begin position="58"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR001488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR001488-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC90627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="225" mass="25549" checksum="1B172DA349B2664F" modified="2018-07-18" version="1">MHLIKKTVAAILFGCISVSVLASPTNPESGKEYIVLTQPQQTDAVGKVEVTEFFYYSCPHCNTLDPYITEWVKKQGNAISFKRVHVDFGQGQQPLQRMYYTLEALGKLDELHARIFQAIHKERQFLRTDQDMLNFVVKNGVDKMKYLETSKSFTIESKIRRAAAMQASYKIEFVPAVFVDGRYMTAPSQLQQAMPGTTEVEGSQNMLPVLDALVLKVQKERGFKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSL4</accession>
    <name>A0A2S9GSL4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_4596</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000038">
        <property type="protein sequence ID" value="PRC90703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90703">
        <property type="protein sequence ID" value="PRC90703"/>
        <property type="gene ID" value="S2091_4596"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015562">
        <property type="term" value="F:efflux transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003423">
        <property type="entry name" value="OMP_efflux"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010131">
        <property type="entry name" value="RND_efflux_OM_lipoprot_NodT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02321">
        <property type="entry name" value="OEP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01845">
        <property type="entry name" value="outer_NodT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0564">Palmitate</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1134">Transmembrane beta strand</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU362097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC90703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="477" mass="52510" checksum="3E09CCDB4B6E08F7" modified="2018-07-18" version="1">MKYSIYLACVLLTGCVVGPNYQRPDLAAQLPKQYQRIEDGPSNQQVEILPDRWWLTFNDSAINQLVDAALLRNLDLASADANIRQARAQLGIIDSASQPQLNANGDISHDQFSKNSELMANIPFPNPRTMFNDYKAGFDASWEIDLFGHTARSIEAAKARLNSIEQQREGVALRVAAEVTRNVIDYRAWQLRSKNAEAIFVDSQHLLDLMQLQQKAGLLSDSDVTEAQTALHNAAAAIPPLQAATLASMMAITVLIDQPQEQVATILQANADIPAVPAHIDSIGLPSDLLLRRPDLRIAERELAAATADIGVAKAEQYPQLTLLASGGLDSITPGKLTNLASRYWNIGPQLSIPLFTGGRLAAQVNSREAARDAALSNYRQAVLSAFSDTEIALIRYQREQQRLTQIKQAFASQHRQLEFAEQRYQLGETNFSYVLQTRQQLAQTNELQLASQQALAENLTALFKSLGGGFNEKPAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSP6</accession>
    <name>A0A2S9GSP6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4557</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000037">
        <property type="protein sequence ID" value="PRC90731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90731">
        <property type="protein sequence ID" value="PRC90731"/>
        <property type="gene ID" value="S2091_4557"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="63"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="90"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="124" mass="13715" checksum="B69296EC991EF438" modified="2018-07-18" version="1">MKMPQGVKQAEIGIWATIAVSALVSLIDKLQGFISEGEFFFALILYSVFCIFPYKIARGSNPARYIFAVLTAFSILGTFAVIAQVSKLDLISTILLLPVQAFIFYRLFHHDATDWFGSAGKSIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSR1</accession>
    <name>A0A2S9GSR1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Saccharopine dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4505</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000036">
        <property type="protein sequence ID" value="PRC90757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90757">
        <property type="protein sequence ID" value="PRC90757"/>
        <property type="gene ID" value="S2091_4505"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005097">
        <property type="entry name" value="Sacchrp_dh_NADP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03435">
        <property type="entry name" value="Sacchrp_dh_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sacchrp_dh_NADP" evidence="1">
        <location>
            <begin position="4"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="366" mass="39351" checksum="7D2A9CE9B1FA1B33" modified="2018-07-18" version="1">MHTILVLGGYGFFGGRICHALASNKHIQLFIAGRDGLKAQQFAVQLGLNPAQGIAIDAHAPLLAQRLMELNIQTVIHTAGPFQGQDYSVARAAIEAGANYIDLADGRDFVAGIDALNESACRRKVLVTSGASSLPALSSAVVDRYLPRFSRLDSIQHGIGSGARAPGLATMRGVFGYCGKPFSRLMGGQWRSVCGWLDLRRYRFPSPVGARLLGNCDVPDLVLFPKRYSSVHTVTFQAGFASSLGHLAVWLCAQLVRLRLVSSLVSLVKPLHTISSWMEAFVSDKGAMFVALEGLGLDKQPLKLTWHLVAAQNHGPYIPCGAAIALAHKLSRGDKLPHGAMPCMGLLSVEDYLAALQNYDIQELPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSY5</accession>
    <name>A0A2S9GSY5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Toxic anion resistance protein (TelA)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4497</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000035">
        <property type="protein sequence ID" value="PRC90834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90834">
        <property type="protein sequence ID" value="PRC90834"/>
        <property type="gene ID" value="S2091_4497"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008863">
        <property type="entry name" value="Toxic_anion-R_TelA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05816">
        <property type="entry name" value="TelA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="146"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="405" mass="44742" checksum="968456629022F8F6" modified="2018-07-18" version="1">MDQQQSVVETNPTPLSDIALMSTNSTLPIPVLRYDLKPEQQMDLSKLTAAQMDRVNQIASSVSFTDTNSLLSFGSDAQRELSQYLDQLLDGMRTSDAGRAGEVTIALATTIKDLNLPKVQKEVAGQDTFAEMFGKLPIVGTWFSALRTMQLNRKKITEHLAAIEQKAQAQITALNANNDKLDRMVIKSVDHIHSMELYMAAGQLVIKRARVEFEQTRLAVEQSRDLVEIAKLRDFAEQLNAFETRVVRINLAHSQSMVSVPEIRATQTAALIEMNNVMDSILFDLPNLKRAILNIASLAETSRAAKATEARRQLSRELNSIGSDELQSAYLKAKESQGGFEADIAALAQSADKLLQTIELGRRLDVTNAGKREKAISDLSAINHKFTDGLLKAGDQFVQQATRSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GT90</accession>
    <name>A0A2S9GT90_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">3-dmu-9_3-mt domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4416</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000033">
        <property type="protein sequence ID" value="PRC90923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90923">
        <property type="protein sequence ID" value="PRC90923"/>
        <property type="gene ID" value="S2091_4416"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06588">
        <property type="entry name" value="PhnB_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009725">
        <property type="entry name" value="3_dmu_93_MTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028973">
        <property type="entry name" value="PhnB-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06983">
        <property type="entry name" value="3-dmu-9_3-mt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF021700">
        <property type="entry name" value="3_dmu_93_MTrfase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="3-dmu-9_3-mt" evidence="1">
        <location>
            <begin position="4"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="160" mass="17390" checksum="9A55C37AEFAE53E2" modified="2018-07-18" version="1">MDTKNTICLWFDGNAMDAAGFYAATFPASSLGAVLRSPGDYPGGKQGDILTVEFTVLGIPCVGINGGPGIKHNEAFSFQITTDDQAETDRLWDAIVQNGGQESQCGWCKDRWGISWQITPRILLAALSDNDPAVSKRVFEAMMTMKKIDISVIEEARRGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTB3</accession>
    <name>A0A2S9GTB3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Polysaccharide biosynthesis protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_4363</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000032">
        <property type="protein sequence ID" value="PRC90962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90962">
        <property type="protein sequence ID" value="PRC90962"/>
        <property type="gene ID" value="S2091_4363"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002509">
        <property type="entry name" value="NODB_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01522">
        <property type="entry name" value="Polysacc_deac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="SSF88713"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51677">
        <property type="entry name" value="NODB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="41"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="78"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="113"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="144"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="168"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="289"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="321"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="365"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="415"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="442"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="domain" description="NodB homology" evidence="2">
        <location>
            <begin position="584"/>
            <end position="843"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC90962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="843" mass="93194" checksum="52BFA91636577927" modified="2018-07-18" version="1">MTMNSTRKSIGINFVTQYLELTIQFAGVLILARILTPADTGLYSVAAFLMTLLHVFRDFGVVNYIIQEAELTKEKIRSAYGVAIILALLVAGAMYACSTLVAGFYKNPAIKDILEVMALSFAVSPFGSLLFGIYRREMQFKRIFFIKIASAICHVAVATILATRGFGALSLAWANFAGILSFGIASNIGRPKDIPWLPQFTNIGKVLSFGSISSLGNAANAIGTNSPDLVIAKVIDMASVGYFSRGNGLVQLFAKLIASALTPLILPYFSQIKRSGTDLREPYLLSVNYLTTLAWPFFSVMALLALPMVRVLYGPQWDASVPIVQMLCIAGAISSLSIFAGHVMIANGQVQHATFAQLLSQPLRVIAVIYASSFGLFGISIAIIAAELLTLMIVSRYLRMTIRINFIELLHACRHSGLITIFSAAGPLLIYLFWPAASGSSWQPLVLGAVTATVGWLLGVILTKHPFFAQITEFLTSIQPPSPSSFKGQQNVTKQFKTAVKILSYKLGILSIYHRFRNKERLTVAMFHRVLPHHDQRRPGADPEWTMDTATFKKCLQFFQRHYHVISMDELAAALHDQKKLPPRSLLITFDDGWADTAEYAQPILDELGMASVVFVAGSVINQAAPFWQEAVYRLLATHPDGITQLNAALIQSSIDVVLVGKERSSEAEIRSVIQQLDTHNPNNLRHLATILQDRANAPAAMLSLIQLHKLAKARHYIGSHGMTHQPLTKVASAESEVKLAQETLSKHLNGLYIESMSFPHGAYDNSVLQVCREAHYRYLFSSDPILNIVNQQSPDNLVFGRIHISERSITDTLNKFHPFMLAYWLFLRPVRLGYVARSNYAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTI7</accession>
    <name>A0A2S9GTI7_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Carbonic anhydrase</fullName>
            <ecNumber evidence="3">4.2.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_4321</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H(+) + hydrogencarbonate = CO2 + H2O</text>
            <dbReference type="Rhea" id="RHEA:10748"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="EC" id="4.2.1.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the beta-class carbonic anhydrase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.1" evidence="3"/>
    <dbReference type="EMBL" id="PUGF01000031">
        <property type="protein sequence ID" value="PRC91025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91025">
        <property type="protein sequence ID" value="PRC91025"/>
        <property type="gene ID" value="S2091_4321"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004089">
        <property type="term" value="F:carbonate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015976">
        <property type="term" value="P:carbon utilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001765">
        <property type="entry name" value="Carbonic_anhydrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015892">
        <property type="entry name" value="Carbonic_anhydrase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036874">
        <property type="entry name" value="Carbonic_anhydrase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11002">
        <property type="entry name" value="PTHR11002"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00484">
        <property type="entry name" value="Pro_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00947">
        <property type="entry name" value="Pro_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53056">
        <property type="entry name" value="SSF53056"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00704">
        <property type="entry name" value="PROK_CO2_ANHYDRASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0456">Lyase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC91025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="299" mass="33328" checksum="61B214297DAF74FA" modified="2018-07-18" version="1">MPQRMSSPSCMQRTPAGLPFGMPGMGEEMEGAMQQAPQLLRQGIRFITLVYNSGYSFKLRSAMTSSKLAKTGRGLTPEQLFQNNRDWAAKITAQDADFFATLAAQQTPEYLWIGCSDSRVPANELLGLLPGELFVHRNIANVVVHSDLNCLSVLQFAVDVLKVKHVIVCGHYGCSGVDAALKRRRIGLADNWLRHVQDVHQKHERYLGEALSDHVRQNRLCELNVIEQVVNLCQTTIVNDAWERQQELTIHGWVYGLQDGLLGDLGMSISSPEMLTANLAQSLSVYEKPQFVKKPPAQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTM5</accession>
    <name>A0A2S9GTM5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Response regulator receiver domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_4251</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000030">
        <property type="protein sequence ID" value="PRC91063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91063">
        <property type="protein sequence ID" value="PRC91063"/>
        <property type="gene ID" value="S2091_4251"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="3"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="137" mass="14749" checksum="BF1ED999D77BED6C" modified="2018-07-18" version="1">MAKILIIEDNPANMKLASFLLRNAGHTALCAVDAETGLTLARDSQPELILMDIQLPDMDGLAATALLKQNPGTASIPVIALTAMAMKDDQEKTRIAGCDAYIAKPLRYMELYAAIDALLLKRKPPAASEENLFGQIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTY9</accession>
    <name>A0A2S9GTY9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_4069</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000027">
        <property type="protein sequence ID" value="PRC91174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91174">
        <property type="protein sequence ID" value="PRC91174"/>
        <property type="gene ID" value="S2091_4069"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002123">
        <property type="entry name" value="Plipid/glycerol_acylTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01553">
        <property type="entry name" value="Acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00563">
        <property type="entry name" value="PlsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="89"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="127"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="154"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="207"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="241"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="274"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="316"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="350"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="379"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="domain" description="PlsC" evidence="2">
        <location>
            <begin position="434"/>
            <end position="550"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="605" mass="66738" checksum="7962289E833AFAD5" modified="2018-07-18" version="1">MGALNDNVFKTALLTILTFDALNWTTMDVGVLNNLIPGLFILPFLLFSASAGQIADKVEKGKLARAVKLLEIFIMSVAALGWFSHQLWLLIVAVAGMGLHSTLFGPVKYAYLPQHLKNDELVGGNGIIEMGTFVGILLGEIIGAVLVVHKPWGIHLVALGTIGIAILGCAVSWKIPRSPAPAPNLVMNWNPFTETVRNIRFSSRNRTVFLSLLGNSWFWFYGAIVLAQFPQYAKEYLHGDHSVFVLLLAVFSVGIGAGSLLCERLSGHKVEIGLVPFGAIGLSLFGIDLYLSSVQYVNTSSVDLFQFVQQTGSWRILFDIVCIGIFGGLYIVPLFALIQTRCDPEHMSRTIAGMNILNSLFMVVAALSAMVMLKSGLSIPQIFLVTACLNGLVAIYIFSLVPEFLMRFLVWLLIHTIHRVRGIDISRIPETGAAVLVCNHVSYLDALVIAACAPRPIRFVMDHRIFNIPVFSWIFKTGKAIPIASAKEDPWIMEHAFVDIAKALHDGDLVCIFPEGRLTQNGELNTFKNGIQKIIERTPVPVIPMALRGLWGSIYSRGSDNPFKRTFRRGLFSKLELIVGEPIPSELATPEFLQEKVQALRGQWQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GU30</accession>
    <name>A0A2S9GU30_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Transcription antitermination protein NusB</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Antitermination factor NusB</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">nusB</name>
        <name evidence="8" type="ORF">S2091_4109</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the NusB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000027">
        <property type="protein sequence ID" value="PRC91214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91214">
        <property type="protein sequence ID" value="PRC91214"/>
        <property type="gene ID" value="S2091_4109"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006353">
        <property type="term" value="P:DNA-templated transcription, termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031564">
        <property type="term" value="P:transcription antitermination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.940.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00073">
        <property type="entry name" value="NusB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035926">
        <property type="entry name" value="NusB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011605">
        <property type="entry name" value="NusB_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006027">
        <property type="entry name" value="NusB_RsmB_TIM44"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11078">
        <property type="entry name" value="PTHR11078"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01029">
        <property type="entry name" value="NusB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48013">
        <property type="entry name" value="SSF48013"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01951">
        <property type="entry name" value="nusB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5 6" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 6" id="KW-0889">Transcription antitermination</keyword>
    <keyword evidence="4 6" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="NusB" evidence="7">
        <location>
            <begin position="18"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005952"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC91214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="155" mass="17249" checksum="4CF01EA8B0A58C92" modified="2018-07-18" version="1">MNTKTQHANPSKSRSPRHRAREFALQGIYQWLLNHEDVAVIEAHIRQAHGFEKADIEHFDAVIYGSIKDVAALRNSIAPLLDRPISELSPVEHAALLIGAYELKNHLEIPYRVVINEAVELTKSFGGIDGHKFVNGVLDKLSSQLRQVEIAAGKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUF3</accession>
    <name>A0A2S9GUF3_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Chromosome partition protein Smc</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">smc</name>
        <name evidence="6" type="ORF">S2091_4002</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Required for chromosome condensation and partitioning.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="3">Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the SMC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000025">
        <property type="protein sequence ID" value="PRC91331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91331">
        <property type="protein sequence ID" value="PRC91331"/>
        <property type="gene ID" value="S2091_4002"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030261">
        <property type="term" value="P:chromosome condensation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007062">
        <property type="term" value="P:sister chromatid cohesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01894">
        <property type="entry name" value="Smc_prok"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003395">
        <property type="entry name" value="RecF/RecN/SMC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024704">
        <property type="entry name" value="SMC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010935">
        <property type="entry name" value="SMC_hinge"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036277">
        <property type="entry name" value="SMC_hinge_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011890">
        <property type="entry name" value="SMC_prok"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06470">
        <property type="entry name" value="SMC_hinge"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02463">
        <property type="entry name" value="SMC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005719">
        <property type="entry name" value="SMC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00968">
        <property type="entry name" value="SMC_hinge"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75553">
        <property type="entry name" value="SSF75553"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02168">
        <property type="entry name" value="SMC_prok_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1 3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SMC hinge" evidence="5">
        <location>
            <begin position="518"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="364"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="170"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="251"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="405"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="694"/>
            <end position="805"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="860"/>
            <end position="901"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="366"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="32"/>
            <end position="39"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC91331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="1177" mass="132955" checksum="1DD336A74F68F9BF" modified="2018-07-18" version="1">MRLTSIKLSGFKSFVELSHFQVPGQLVGVVGPNGCGKSNIIDAVRWVLGESKASELRGESMQDVIFNGSTHRKPAGRASVELVFDNSLGKAAGQWGQYAEISVKRTLTRDGTSTYYINNQAVRRRDIQDIFLGTGLGPRAYAIIGQGMISRIIEARPEELRIFLEEAAGVSRYKERRRETENRIHSTNENLVRVEDILRELNVNLEKLEAQAAVATKFRTLQADQEEKQKLLWLLRQKEASTEQKKYFRDIEQAQTDLEQNTAQLRHVELELEQMRQAHYSVGDKMHQAQGHLYQTNSEIGSLEAQIRFVVDSRTRLQMQLNTLKVQREQWQRQEQDQQNELNEAAVEIEELAARSEEAKQIAEQHGQQLPAQEAAWRSGQQKTADGRAKIMQMQQQIELESAHQRNANNVLNGLVLRRERLQQEKGGLQLPDQTHLTNLSDQLEEKRFDLEQAQMQLDEVEIQHPELDTARRTAQQQVQSESASNAQLDARLAALTQLQISVQSEGKVQPWLAKHELTNLPRLWQKLHIKDGWETALEAVLRERTQALEVSNLDWAKAFFGDAPPAKLAFYSAQAIPAATNFDPNFTSLISLLQLNDANLRAVLQDWLQHVYIAEDAATALMNRAKLPAGGCFVTRQGHLITASSVRFYASDAEQDGMLARAQEIEHLQKQTRVQQLLAEQARNTSIRAEAAYTQATQRLQELRVRVQSLTQQVHSLQIEVMKLSEVQARFNQRSVQIESDLAEINAQEQEQQQLKMESEQKFEELDIDLAQQQEQFEEWQTTQLEQEQQLNLARAKVRDLELAAQQATFAERTHHQKVEELKRTIATASTQAASVFESMQQGMLELENMEDLSVQAGLHDLLEKRSAQERALSDARHELDQLAQQLRSHEDAKNQAERSMQPQRDKIMELQLKEQAARLNQEQYTQALTDVGMTDEQLAALSEKLVDDLKPSYLQGEVTRLGNAVIALGAVNLAALDELAQASERKLFLDAQYADLTEAIQTLQDAIHKIDIETRGLLQDTFDKVNYHFAELFPILFGGGQAKLVMTGDEILDSGVQVMAQPPGKKNATIHLLSGGEKALTATALVFSMFQLNPAPFCLLDEVDAPLDDSNTERFCNMVKKMSVNTQFLFISHNKIAMEMAQQLIGVTMQEQGVSRIVAVDMESAVNFATEAEAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUS6</accession>
    <name>A0A2S9GUS6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GDSL-like Lipase/Acylhydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3878</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000023">
        <property type="protein sequence ID" value="PRC91463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91463">
        <property type="protein sequence ID" value="PRC91463"/>
        <property type="gene ID" value="S2091_3878"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001087">
        <property type="entry name" value="GDSL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00657">
        <property type="entry name" value="Lipase_GDSL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015773006" evidence="1">
        <location>
            <begin position="26"/>
            <end position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="403" mass="44259" checksum="ABB0610D61D4CFA7" modified="2018-07-18" version="1">MKNLRTMLLGLCCAVMTLASSASYAVGSNTYTYLRCFYRVNPSNLTPATTYVWARDPSSNDYYHVNGYWWADGLLEWENMFYSETTQSTLLSVCKSTLSNQGIKQPVAMYAGADTDASLNYTVWSIDPTVQSGAINKIVAFGDSLSDMQNMFNGTDWILPNTHSYFAGRFSNDKNWLDYLSVNLNLPVYNWAVAGAAADEYFVIPGASEQVASWATYMQSAPNYQVKNTLFTLLVGGNDLVNYGRSVSSIIAGEQLALVNLIAAGGKNILLVNLPDVSRAPVFALRTDAASVKAQVVQFNQQLAQMAASLQASYGSAVNIKVFDANSLFTDLLNNPSKYGVTNTTQSCLNINSDSTLNYTYTWSPRSNCTNADTFVFWDLLHPTTHTHSLLGSYAASFVQSNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUV7</accession>
    <name>A0A2S9GUV7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3771</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000022">
        <property type="protein sequence ID" value="PRC91493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91493">
        <property type="protein sequence ID" value="PRC91493"/>
        <property type="gene ID" value="S2091_3771"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="28"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="312" mass="35096" checksum="C22F3F3A8CD25511" modified="2018-07-18" version="1">MRYYKFLLLKNIWQIMANHLPKIGNVDFDWNDLKYALTVARHGGLTHAAKLLGTSASTVSRHIQQLETSLGQTLFLRQQSGYLLTDQGKEVLELIASVEQALLALERHQKPDSPTQSVSGLVRLACAEMMASHLIVPNLPKLYQAHPDLQVELAVDIRLADLNRREADLALRLVAPGGKVGEQDYIVHPLGKMPFATYVSKHHEVSNNYISWGQDWAHLPMVEWLAQQFKTQPAVLVSNSANAQIQAARHGIGIVMLPRYVGDVEPDLREIELSKTKLCRDIWLVYHRDLKASSRVQVMREFLSTSIQATLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUW7</accession>
    <name>A0A2S9GUW7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Molybdopterin-binding domain of aldehyde dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3782</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000022">
        <property type="protein sequence ID" value="PRC91504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91504">
        <property type="protein sequence ID" value="PRC91504"/>
        <property type="gene ID" value="S2091_3782"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000674">
        <property type="entry name" value="Ald_Oxase/Xan_DH_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008274">
        <property type="entry name" value="AldOxase/xan_DH_Mopterin-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037165">
        <property type="entry name" value="AldOxase/xan_DH_Mopterin-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012368">
        <property type="entry name" value="OxRdtase_Mopterin-bd_su_IorB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02738">
        <property type="entry name" value="Ald_Xan_dh_C2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036389">
        <property type="entry name" value="IOR_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01008">
        <property type="entry name" value="Ald_Xan_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56003">
        <property type="entry name" value="SSF56003"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ald_Xan_dh_C" evidence="1">
        <location>
            <begin position="238"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="759" mass="81465" checksum="995583D47B2DAF6F" modified="2018-07-18" version="1">MGLTRRRFLLGGLGMTGALIVGWGVSPMRQRLQATVPLPVIDGSVSLNGWMEIATNGRVTMFLHKSEMGQGVSTALPMLLAEELDVPLAMVDIVPAGMDKIYGNVAMLVDGLPFHPDDSGMLKHGAQWMTGKFARELGLQVTGGSSSVKDSWLVLRQAGSAARAMLIASAAQQWNVPVSECHTKAGMVLHTSGKQAGYGELAALAVHSNPAQIRLKNPSEFTLIGQPQARRDSADKTTGKAQFGLDVRLPGMLYAAVKMCPKLGGKLRSMNDADIIKMPGVVKVHSLADLNARVTSVAGVLVIAKTYWQARVALDAMNLEWDDGVGSTGSALSSASVLHELRSKLDTETGFTYFKQGHIKAEAKQDAITTQTLNAEYSAPFLAHATMEPMNCTAQVHNGRVSLWVGTQTPTLAVKIAAQVAQVNSDQIELHHTFLGGGFGRRLEVDMVAQAVAAALQTNGVPVQLIWSREEDIGHDFYRPAAVARFKATVDQVGQVISYENTSASGSITQQVLKRYFGLAAMGPDKTTAEGEFDMPYEFPNQKIAHVIVPTAVPIGYWRSVGHSHNAFFKESFIDELAHAAKQTPLQFRRGLLKQHPRYLAVLNAAMVLAEQGGVLPAGHAHGIALHQSFGTIVAQVAEVSVQDKEIIVHKVSCAVDCGIVVNPNIVRQQMESAVLFGLSAALFGEITFKDGKVEQSNFHDYVVIRMNQAPQVEVVIIASAEAPEGIGEPGTPPIAPAVANALFNLTGQRLRSLPLRLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GV21</accession>
    <name>A0A2S9GV21_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Amino acid/peptide transporter (Peptide:H+ symporter)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_3691</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000021">
        <property type="protein sequence ID" value="PRC91575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91575">
        <property type="protein sequence ID" value="PRC91575"/>
        <property type="gene ID" value="S2091_3691"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904680">
        <property type="term" value="F:peptide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006857">
        <property type="term" value="P:oligopeptide transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17346">
        <property type="entry name" value="MFS_DtpA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005279">
        <property type="entry name" value="Dipep/tripep_permease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000109">
        <property type="entry name" value="POT_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018456">
        <property type="entry name" value="PTR2_symporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11654">
        <property type="entry name" value="PTHR11654"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00854">
        <property type="entry name" value="PTR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00924">
        <property type="entry name" value="yjdL_sub1_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01022">
        <property type="entry name" value="PTR2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0571">Peptide transport</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="39"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="77"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="114"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="141"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="180"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="205"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="256"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="302"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="334"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="367"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="399"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="434"/>
            <end position="453"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC91575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="469" mass="51209" checksum="8D2111853FC76E17" modified="2018-07-18" version="1">MTTTQMMNQATFDDETDRSFFGHPRGLAYISFAEAWERFSFYGMQTLLVLYMVQQLLLPGHIEHITGFTAFRAFIEYIYGGTLSTVALASAIFGLYSGFVYLTPIVGGLIADRWLGKTTTITIGALLMAAGHFLMAFDFSFLIALLCLLCGVGCFKGNLASQVSELYSPSDMRRADAFQIYFLFINAAVIAAPLIAGTLGEVYGWHYGFGVAGVGMLISLVVYLSGRKWLPVDQVVTTKTVTATPKAILTANERRAIYVLLFLLPVLAIGSVGNQEVFNAYLLWVPKNIDLVFFGRQMPTTWLITLDAAVSVTCLVLSLAFWRWWSKRFNEPTEIIKITIGLSLCTAALLALVMAATISSSGQKAGIGWVLAFEVLNSLGFANIFPVGLALYARAAPKAVAGTIMGVYYLHLFMGNNLVGWLGGLLERLSGTQFWLLHAALVGTSMALVYAIARLFGHYLVPANAENTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GV50</accession>
    <name>A0A2S9GV50_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">ThiS: thiamine biosynthesis protein ThiS</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3721</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000021">
        <property type="protein sequence ID" value="PRC91605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91605">
        <property type="protein sequence ID" value="PRC91605"/>
        <property type="gene ID" value="S2091_3721"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016155">
        <property type="entry name" value="Mopterin_synth/thiamin_S_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010035">
        <property type="entry name" value="Thi_S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003749">
        <property type="entry name" value="ThiS/MoaD-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34472">
        <property type="entry name" value="PTHR34472"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02597">
        <property type="entry name" value="ThiS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54285">
        <property type="entry name" value="SSF54285"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01683">
        <property type="entry name" value="thiS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="67" mass="7157" checksum="AAFF271A2F1F105B" modified="2018-07-18" version="1">MMEIILNGAAHQLTEQQSVAELVAALNLTQQAIAVAVNRSIIARPNWGQHQLQAQDQVDVVRAIGGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVH4</accession>
    <name>A0A2S9GVH4_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8">Acetolactate synthase</fullName>
            <ecNumber evidence="4 8">2.2.1.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">S2091_3648</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>H(+) + 2 pyruvate = (2S)-2-acetolactate + CO2</text>
            <dbReference type="Rhea" id="RHEA:25249"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:58476"/>
            <dbReference type="EC" id="2.2.1.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="8">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
        <text evidence="8">Binds 1 thiamine pyrophosphate per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 8">Amino-acid biosynthesis; L-isoleucine biosynthesis; L-isoleucine from 2-oxobutanoate: step 1/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Amino-acid biosynthesis; L-valine biosynthesis; L-valine from pyruvate: step 1/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the TPP enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.2.1.6" evidence="4 8"/>
    <dbReference type="EMBL" id="PUGF01000020">
        <property type="protein sequence ID" value="PRC91710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91710">
        <property type="protein sequence ID" value="PRC91710"/>
        <property type="gene ID" value="S2091_3648"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00047">
        <property type="reaction ID" value="UER00055"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00049">
        <property type="reaction ID" value="UER00059"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003984">
        <property type="term" value="F:acetolactate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009099">
        <property type="term" value="P:valine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd02015">
        <property type="entry name" value="TPP_AHAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012846">
        <property type="entry name" value="Acetolactate_synth_lsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039368">
        <property type="entry name" value="AHAS_TPP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012000">
        <property type="entry name" value="Thiamin_PyroP_enz_cen_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012001">
        <property type="entry name" value="Thiamin_PyroP_enz_TPP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045229">
        <property type="entry name" value="TPP_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011766">
        <property type="entry name" value="TPP_enzyme-bd_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18968">
        <property type="entry name" value="PTHR18968"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02775">
        <property type="entry name" value="TPP_enzyme_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00205">
        <property type="entry name" value="TPP_enzyme_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02776">
        <property type="entry name" value="TPP_enzyme_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="SSF52467"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00118">
        <property type="entry name" value="acolac_lg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7 8" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0786">Thiamine pyrophosphate</keyword>
    <keyword evidence="6 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TPP_enzyme_N" evidence="11">
        <location>
            <begin position="8"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="domain" description="TPP_enzyme_M" evidence="9">
        <location>
            <begin position="197"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="domain" description="TPP_enzyme_C" evidence="10">
        <location>
            <begin position="396"/>
            <end position="543"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PRC91710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="573" mass="63246" checksum="FB8949057BB32EB6" modified="2018-07-18" version="1">MSTNSDLTGAEILVRCLAEEGVEHVFGYPGGAVLYIYDAIYKQDKFQHVLVRHEQAALHAADAYSRSSNKVGVALVTSGPGVTNAVTGLATAYMDSIPMIVISGQVPSSAIGQDAFQECDTVGITRPCVKHNFLVKDVRDLALTIKKAFYIATTGRPGPVLIDIPKDISAHKCAYSYPKEVEMRSYKPVDKGHSGQIRKALQLLMQAERPMIYTGGGVILANASAELNKLVDQLGFPCTNTLMGLGAYRASDEKFVGMPGMHGTYEANMAMQNCDVLIAIGARFDDRVIGNPKHFASQQRKIIHIDIDPSSISKRVKVDIPIVGNVKDVLQELLSQLSVAENRPNPASISAWWQQINEWRKRDCLKYVDSSVVIKPQSVVEKVWQITKGDAFITSDVGQHQMWAAQYYRFDKPRRWINSGGLGTMGVGLPYAMGVQMANPDATVACITGEGSIQMCIQELATCKQYHLTPKIILLNNRFLGMVRQWQQIDYSSRYSESYMESLPDFSKLAEAYGHVGMKIENPADVDGALHDAFAMKDRLVFMNFITDQTENVWPMVKTGKGLSEMLLGSEDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVN1</accession>
    <name>A0A2S9GVN1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Dehydrogenases with different specificities (Related to short-chain alcohol dehydrogenases)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3513</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000019">
        <property type="protein sequence ID" value="PRC91758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91758">
        <property type="protein sequence ID" value="PRC91758"/>
        <property type="gene ID" value="S2091_3513"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="261" mass="27026" checksum="A7FACDF442323120" modified="2018-07-18" version="1">MTDKVVNLKGKHALVTGGTRGIGLAIAQALLQQGAKVTIVARSLSNLQQVAEKLSAFGEVNCVELDLTDSSAVAAAFNTAVAQFGPIAILVNNAGQAHSAPFMKTDLALFNSMLSVNLTSVLLCTQAVLPGMLEMGWGRIVNVASTAGLTGYGYASAYCATKHAVIGLTRSLALEVAKKGITVNAVCPGYTETDLIQQAIANIVKKTGRTEEQARAELAASNPQGRLVQVEEVANAVAWLCMPASSAMNGQAIPVDGGELM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVS5</accession>
    <name>A0A2S9GVS5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Enoyl-CoA hydratase/carnithine racemase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3511</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the enoyl-CoA hydratase/isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000019">
        <property type="protein sequence ID" value="PRC91756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91756">
        <property type="protein sequence ID" value="PRC91756"/>
        <property type="gene ID" value="S2091_3511"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.12.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018376">
        <property type="entry name" value="Enoyl-CoA_hyd/isom_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014748">
        <property type="entry name" value="Enoyl-CoA_hydra_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00166">
        <property type="entry name" value="ENOYL_COA_HYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="284" mass="30883" checksum="05EEB17C04139668" modified="2018-07-18" version="1">MNYLAGKADQLPGNHLTLADYKAQHFGFNVHEAIATITLNRPERKNPLTFESYAELRQLFLDLAYADDVKAVVLVGAGDNFCSGGDVFEIIGPLTQLDMPSLLRFTRMTGDLVKAMRACPQPIIAAVDGICAGAGAILALSSDIRLGTERSKTAFLFTRVGLAGCDMGACALLPRVIGQGRAADLLYTGRSMSGVEAERWGFFNRLCEPDLVLQQAQAYAAELSRGPTFAHGMTKKMLQQEWNMGVDQAIEAEAQAQAICMATNDFHRAYHAFSAKQKPQFEGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVS9</accession>
    <name>A0A2S9GVS9_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Pyrrolidone-carboxylate peptidase</fullName>
            <ecNumber evidence="9">3.4.19.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">5-oxoprolyl-peptidase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Pyroglutamyl-peptidase I</fullName>
            <shortName evidence="9">PGP-I</shortName>
            <shortName evidence="9">Pyrase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">pcp</name>
        <name evidence="12" type="ORF">S2091_3566</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 9">Removes 5-oxoproline from various penultimate amino acid residues except L-proline.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9 10">
            <text>Release of an N-terminal pyroglutamyl group from a polypeptide, the second amino acid generally not being Pro.</text>
            <dbReference type="EC" id="3.4.19.3"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 9">Belongs to the peptidase C15 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.3" evidence="9"/>
    <dbReference type="EMBL" id="PUGF01000019">
        <property type="protein sequence ID" value="PRC91811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91811">
        <property type="protein sequence ID" value="PRC91811"/>
        <property type="gene ID" value="S2091_3566"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016920">
        <property type="term" value="F:pyroglutamyl-peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00501">
        <property type="entry name" value="Peptidase_C15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00417">
        <property type="entry name" value="Pyrrolid_peptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000816">
        <property type="entry name" value="Peptidase_C15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016125">
        <property type="entry name" value="Peptidase_C15-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036440">
        <property type="entry name" value="Peptidase_C15-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029762">
        <property type="entry name" value="PGP-I_bact-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033694">
        <property type="entry name" value="PGPEP1_Cys_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033693">
        <property type="entry name" value="PGPEP1_Glu_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23402">
        <property type="entry name" value="PTHR23402"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01470">
        <property type="entry name" value="Peptidase_C15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015592">
        <property type="entry name" value="Prld-crbxl_pptds"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00706">
        <property type="entry name" value="PYROGLUPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53182">
        <property type="entry name" value="SSF53182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00504">
        <property type="entry name" value="pyro_pdase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01334">
        <property type="entry name" value="PYRASE_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01333">
        <property type="entry name" value="PYRASE_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 9" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 9" id="KW-0788">Thiol protease</keyword>
    <feature type="active site" evidence="9 10">
        <location>
            <position position="81"/>
        </location>
    </feature>
    <feature type="active site" evidence="9 11">
        <location>
            <position position="144"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PRC91811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="216" mass="23091" checksum="0861CA8F1E3CBBC0" modified="2018-07-18" version="1">MMKTILLTGFEPFAQSDINPSWEVARALDGWRTEQFIVHSVQLPCVFGTAQQAMIHAIEQYRPDVVIALGQAGGRCEITPERIAINIDDARIPDNAGSQPIDIPVAAAGPAAYFSTLPIKAIVQNLSANGIPSAVSQSAGTFVCNHVFYGLMHYLATKQNPARAGFIHVPSLPEQAALHPGEASMALADMLHGLRLAIQTSCSQQQDIAVTGGQIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVW3</accession>
    <name>A0A2S9GVW3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3394</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000018">
        <property type="protein sequence ID" value="PRC91838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91838">
        <property type="protein sequence ID" value="PRC91838"/>
        <property type="gene ID" value="S2091_3394"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="70" mass="7778" checksum="D34E411051FB579B" modified="2018-07-18" version="1">MDADNNIVVAQVLDERLNNDIEAAVNLGLAAALLGEVHDGMRLMQELGVPYEISSRVLLNKTKRRSSDWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GW71</accession>
    <name>A0A2S9GW71_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3293</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000017">
        <property type="protein sequence ID" value="PRC91951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91951">
        <property type="protein sequence ID" value="PRC91951"/>
        <property type="gene ID" value="S2091_3293"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="80" mass="9116" checksum="0FD0172F9957054B" modified="2018-07-18" version="1">MNRQLTLYLPNPLAARVTLFLSTKGQPLTTCRSVDERLGKNHKSSLKNLNAVMAATYYFRLKRQVAGDRVCAEFIKNRSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWH5</accession>
    <name>A0A2S9GWH5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">tRNA and rRNA cytosine-C5-methylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_3207</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000016">
        <property type="protein sequence ID" value="PRC92072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92072">
        <property type="protein sequence ID" value="PRC92072"/>
        <property type="gene ID" value="S2091_3207"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001510">
        <property type="term" value="P:RNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031341">
        <property type="entry name" value="Methyltr_RsmF_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001678">
        <property type="entry name" value="MeTrfase_RsmB/NOP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023267">
        <property type="entry name" value="RCMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22807">
        <property type="entry name" value="PTHR22807"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01189">
        <property type="entry name" value="Methyltr_RsmB-F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17125">
        <property type="entry name" value="Methyltr_RsmF_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR02008">
        <property type="entry name" value="RCMTFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51686">
        <property type="entry name" value="SAM_MT_RSMB_NOP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4 6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SAM_MT_RSMB_NOP" evidence="5">
        <location>
            <begin position="140"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4">
        <location>
            <position position="354"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="254"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="301"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC92072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="418" mass="46046" checksum="791E2A8FDA8EC622" modified="2018-07-18" version="1">MRLPPALIGHTEEVLREVLRFTAPADSTLSRYFRDHTRLGARERGVIAESIYGLLRNKAVYTSFSESGSGALIRRMALLALADGVGIDALGGLTELETEWLTRVMEIDRNHLPLELRVNLPTWLFQKLTEQLGEEGMLAFTKATNEPAPLDLRVNTIKAERDAVRAELALAPIQAEPTPFAPDGLRVLKKPSLQNLPLFKSGAIEVQDEGSQLLAQIVGAKRGEMVVDFCAGAGGKTLALGAAMRNTGRLYAFDISEKRLAKLKPRLARSGLSNVHPVLIAHERDAKIKRLAGKIDRVLVDAPCSGLGTLRRNPDVKWRQLPTAIAELNVKQAAILDSAARLVKPGGRLVYATCSILKEENEAIAEQFLATHAEFELLPMRDVLVEQKIVLEMDSYLKLSPEQHQTDGFFAAAFQRKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWJ9</accession>
    <name>A0A2S9GWJ9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3242</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000016">
        <property type="protein sequence ID" value="PRC92107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92107">
        <property type="protein sequence ID" value="PRC92107"/>
        <property type="gene ID" value="S2091_3242"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="3"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="298" mass="32856" checksum="61A1D44A9BF18AE2" modified="2018-07-18" version="1">MNLELRQLRYFIAVAEELHVGRAAQRLHMTQPPLSQAIQGLEAMLGADLFIRQKRGITLSAAGHALLPEARRLIKDSLALPELVRCAALGEVGHISLAFVSTADYNLLPPLLRDFRSRYPQVQISLREATSDVQLEALRLGQIDLGLMIPPIPEKLADMLNYQAILSEPLILAAPSDSTWLSNKLQVSLLECQGQPLIIFPRAIAPAFYDSILGCFQSVGITPEIGQEAIQMQTIIGLVSAGMGIALVPQSVSNLKRPGVVYRELEQITPLIETGLAWRRDNHSPVLHAFIELTRKNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWU8</accession>
    <name>A0A2S9GWU8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Chromate transport protein ChrA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_3110</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92194">
        <property type="protein sequence ID" value="PRC92194"/>
        <property type="gene ID" value="S2091_3110"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015109">
        <property type="term" value="F:chromate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003370">
        <property type="entry name" value="Chromate_transpt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02417">
        <property type="entry name" value="Chromate_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="18"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="57"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="90"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="128"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="175"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC92194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="192" mass="21207" checksum="9E5844D836EC83DA" modified="2018-07-18" version="1">MQPALQISLNWSDWLDLFQHYFMLSMLSIGGAISTLPEMHRFLVEQHHWLTETQFNASIAIGQASPGPNLLFIALLAWNVGINSGSVAAGLFSVLIAMVGILVPSTTLTYLVAGWLRNNNGLRPVRAFKQGLAPIVIALLIATGWIMASSHPQGEWHLWLVTIVTAVLIWRTRIHMLWLIGAGALLGWFGFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWV4</accession>
    <name>A0A2S9GWV4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_3097</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92181">
        <property type="protein sequence ID" value="PRC92181"/>
        <property type="gene ID" value="S2091_3097"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006744">
        <property type="term" value="P:ubiquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07377">
        <property type="entry name" value="WHTH_GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1410.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028978">
        <property type="entry name" value="Chorismate_lyase_/UTRA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011663">
        <property type="entry name" value="UTRA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00392">
        <property type="entry name" value="GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07702">
        <property type="entry name" value="UTRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00035">
        <property type="entry name" value="HTHGNTR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00866">
        <property type="entry name" value="UTRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64288">
        <property type="entry name" value="SSF64288"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50949">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0831">Ubiquinone biosynthesis</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="4">
        <location>
            <begin position="46"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="11"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC92181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="279" mass="31164" checksum="CB3443B3586FACED" modified="2018-07-18" version="1">MGFVVKSRSMNPDLPNPSATDQVSQTTLTPTVAHAPSPNQSAPTFSPLYQQIKSLITQSLQSGEWKPGELIPSEVELAVRFKVSQGTVRKAIDELSAENVVVRRQGKGTFVATHHEARAQFRFLRLKPNEGVQQYPSNRILEVKRIRAPAEIAKLLDIKVADSVIFIRRVQSFDGVPTILEELWLPGAIFKGLTAELLNEYKGPMYALFETEFGTHMIRASEQLRSVAADQAAADLLKIDVGAPLLNVERVSYTYGDKPVEFRRGLYLTLNHHYHNELS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWZ7</accession>
    <name>A0A2S9GWZ7_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">50S ribosomal protein L9</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rplI</name>
        <name evidence="9" type="ORF">S2091_3160</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Binds to the 23S rRNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the bacterial ribosomal protein bL9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92244">
        <property type="protein sequence ID" value="PRC92244"/>
        <property type="gene ID" value="S2091_3160"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.430.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.5.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00503">
        <property type="entry name" value="Ribosomal_L9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000244">
        <property type="entry name" value="Ribosomal_L9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009027">
        <property type="entry name" value="Ribosomal_L9/RNase_H1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020594">
        <property type="entry name" value="Ribosomal_L9_bac/chp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020069">
        <property type="entry name" value="Ribosomal_L9_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036791">
        <property type="entry name" value="Ribosomal_L9_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020070">
        <property type="entry name" value="Ribosomal_L9_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036935">
        <property type="entry name" value="Ribosomal_L9_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21368">
        <property type="entry name" value="PTHR21368"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03948">
        <property type="entry name" value="Ribosomal_L9_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01281">
        <property type="entry name" value="Ribosomal_L9_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55653">
        <property type="entry name" value="SSF55653"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55658">
        <property type="entry name" value="SSF55658"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00158">
        <property type="entry name" value="L9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00651">
        <property type="entry name" value="RIBOSOMAL_L9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 7 9" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 7" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="RIBOSOMAL_L9" evidence="8">
        <location>
            <begin position="13"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00503"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS00651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC92244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="150" mass="15864" checksum="96150297C315C9D2" modified="2018-07-18" version="1">MQIILLEKVVNLGNLGDVVRVKDGYARNFLIPQRKARRATTSALAEFEVKRAELENAAAARLAVATVAGTKLTGLTVQISQKSGVDGRLFGSVTNADVAEALTKQGFAVEKAQIRMPQGPLKIVGDHAVSVALHTDVVVDIIVAVLGDHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GX14</accession>
    <name>A0A2S9GX14_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="11">4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">S2091_2922</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92263">
        <property type="protein sequence ID" value="PRC92263"/>
        <property type="gene ID" value="S2091_2922"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040845">
        <property type="entry name" value="Arnt_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038731">
        <property type="entry name" value="RgtA/B/C-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18583">
        <property type="entry name" value="Arnt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13231">
        <property type="entry name" value="PMT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="92"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="119"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="217"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="267"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="298"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="324"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="350"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="391"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="419"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="domain" description="PMT_2" evidence="9">
        <location>
            <begin position="70"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="domain" description="Arnt_C" evidence="10">
        <location>
            <begin position="453"/>
            <end position="556"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF13231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF18583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC92263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="560" mass="63720" checksum="96D1A1497E86E64D" modified="2018-07-18" version="1">MNNNTNNNSIRFPIWLWISLFLFLVIWFYMLGARTLVPTDEGRYAEMAREMVATGDWITPRLNAIKYFEKPPLQTWMNALTFSAFGLGEWQARLWTGLSALFGIFLVGYTGTRIANKPVGITAAAVLGSSFWWAGLGHVNSLDMGLSGMMTLALCGLLLAQRDQATKTEQRNGMLLCWLGMALATMSKGPMGIILPGAVLFLYTFAARDWRIWQRLHLVKGLLLFFAITTPWFVLVSRDNPEFLHFFFIHEHWERFTSKVHHRDGPLYYFIPLLIVGIFPWLGLLVQSMWNGTKQQAATFQAGKLLLIWALFIFFFFSISSSKLPSYILPIFPALALLIAMHLERPAYRGIVITSAMLSLFGLIGLGFWLFFGQIPSLNKNTYDLPLYIAYLPYIAIASGLMLIGGIKAWYLARTKQQVAIWVLAWAGFLSGQILMMGHEPWGRYIAGTEHLAAIQAELKPETSIYAVGRYEQSLPFYLRHTTILVEHPDEMEFGLQYEPQLWIPKREDFVKQWLDHQANGVAALAIIRPDIYDAFVQQGIPMRVIAQDPRRVIVSSKLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GX21</accession>
    <name>A0A2S9GX21_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">4HBT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2910</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92251">
        <property type="protein sequence ID" value="PRC92251"/>
        <property type="gene ID" value="S2091_2910"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003736">
        <property type="entry name" value="PAAI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006683">
        <property type="entry name" value="Thioestr_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03061">
        <property type="entry name" value="4HBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00369">
        <property type="entry name" value="unchar_dom_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4HBT" evidence="1">
        <location>
            <begin position="50"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="142" mass="15048" checksum="74A2E59B1CB1FE8C" modified="2018-07-18" version="1">MSKSINITSESLNQFGVGTLTAHLGISITSVENGEVSAELPIQPFLLAPNGYLHAGSVVTLADTASGYGCMANLPEGATGFTTIELKSNHLGTAREGVIYCVAKPVHLGKTTQVWDAIVKNKATDQTIALFRCTQLILYPKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GX22</accession>
    <name>A0A2S9GX22_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2921</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92262">
        <property type="protein sequence ID" value="PRC92262"/>
        <property type="gene ID" value="S2091_2921"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036748">
        <property type="entry name" value="MTH938-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007523">
        <property type="entry name" value="NDUFAF3/AAMDC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21192">
        <property type="entry name" value="PTHR21192"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04430">
        <property type="entry name" value="DUF498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64076">
        <property type="entry name" value="SSF64076"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="146" mass="16296" checksum="34AC9FD898617BB4" modified="2018-07-18" version="1">MRFSLTSALIPPCKPEMKLHNTQNQQYQTVTAYDDHSVEINAITFKHSLLVLPELPPITWPVSNFAALTEEHFQTIAALRPDVVILGTGIKQRFAHPKLTACLINQRIGVESMDSQAACRTYNILMTEGRKVALALIIEAKEENPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GX36</accession>
    <name>A0A2S9GX36_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 8 10">Integration host factor subunit alpha</fullName>
            <shortName evidence="8">IHF-alpha</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">ihfA</name>
        <name evidence="8" type="synonym">himA</name>
        <name evidence="12" type="ORF">S2091_2943</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8 10">This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8 10">Heterodimer of an alpha and a beta chain.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 8 9">Belongs to the bacterial histone-like protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92284">
        <property type="protein sequence ID" value="PRC92284"/>
        <property type="gene ID" value="S2091_2943"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd13835">
        <property type="entry name" value="IHF_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00380">
        <property type="entry name" value="IHF_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000119">
        <property type="entry name" value="Hist_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020816">
        <property type="entry name" value="Histone-like_DNA-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010992">
        <property type="entry name" value="IHF-like_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005684">
        <property type="entry name" value="IHF_alpha"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33175">
        <property type="entry name" value="PTHR33175"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00216">
        <property type="entry name" value="Bac_DNA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01727">
        <property type="entry name" value="DNABINDINGHU"/>
    </dbReference>
    <dbReference type="SMART" id="SM00411">
        <property type="entry name" value="BHL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47729">
        <property type="entry name" value="SSF47729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00987">
        <property type="entry name" value="himA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00045">
        <property type="entry name" value="HISTONE_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 10" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="5 8 10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8 10" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 8 10" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3 8 10" id="KW-0810">Translation regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="105"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00018329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00380"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PRC92284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="159" mass="17992" checksum="A2681E722CE27F1A" modified="2018-07-18" version="1">MLNLKELEIEVELDVEQIRQQMKDETLTEPQSELDANLNRAKQEAQARMMAAKQLTTLTKAELAELLFEQVGLNKREAKDMVETFFDEIRNALERGEAVKLSGFGNFQLRDKPQRPGRNPKTGEEIPISARRVVTFHASQKMKSMVDQLSGQSASSDSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GX76</accession>
    <name>A0A2S9GX76_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2981</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92322">
        <property type="protein sequence ID" value="PRC92322"/>
        <property type="gene ID" value="S2091_2981"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003810">
        <property type="term" value="F:protein-glutamine gamma-glutamyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020916">
        <property type="entry name" value="Gln_gamma-glutamylTfrase_bac"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20085">
        <property type="entry name" value="TGL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015689957" evidence="1">
        <location>
            <begin position="30"/>
            <end position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="419" mass="47767" checksum="3181511FB7FBEFB0" modified="2018-07-18" version="1">MKSVVTSMLLPALLSVLVLFTLMSFRVQAGNSHYSDDVTQHRAAYTNNNHGEDGVKFSCSIAQLNEIDQQMSVYFIQLGINATLIQRQLNPQAASLLFTLATPPNDFSTLNFRSRPEMQIRDQLISLPSAGGSMITVLTVSEKEIVLALMQHGRLTEFSGEQCNAETFIDHVKIRQNTVAWAELLEWGWPDGGKAKWNKKYWNKGTPLRGVSPSVAVADAFENQNKYSIGCYTATKLVMVQGILDYYHRIKKSPHELARVERRLMADGEPLVNIEPRAFWFFEEDFDANRLWENGKLLEMRYNIPPRNFVPGDWGYILNTDPKTKNKIGYEGSNAIYLGRGQFDDYYNDHNHSYLLREKLDEVYQWRNKVFSRSRDIDKVLPLTEGEMNALESAPDQGGLIMDTRAFFMISPSSSETLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXE2</accession>
    <name>A0A2S9GXE2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Archaeal ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2764</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92389">
        <property type="protein sequence ID" value="PRC92389"/>
        <property type="gene ID" value="S2091_2764"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="373" mass="41918" checksum="869DD597F3AB8A0F" modified="2018-07-18" version="1">MSIKIAHNNWHFARPQLADAYLNSFELGLSSARGLFARRRMGKTEFLKQDLIPAAQTKGYVCVYVNLWEIQTDPAISLLAAIHSALSPRGISKMWNNLSAPLKKIKASAKMAGIEGSLEAELNEAKQQAGSLLVEAMALFDAGKANMLLIIDEAQVLADPQHSIFTHALRAALDIRKERIKVVFAGSSESTLRRMFGVSSEPFYNWAPLEPFPLLGDEFIKAMVKKVATISKFPLPLPDALNAFEELNRTPEFFRRYLDNYLTNPLPGAQHALEHTKNLLFNDDGFITQWNELLATDQYLLLQIAHDNTDMYSAKALLQLGQQLGLDKPASKSTVQNALTRLAKKNIVTKMERNYQFEDIAFAEWLKKSDFFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXM7</accession>
    <name>A0A2S9GXM7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2835</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92460">
        <property type="protein sequence ID" value="PRC92460"/>
        <property type="gene ID" value="S2091_2835"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HATPase_c" evidence="1">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02518"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="65" mass="7063" checksum="800A4E64A8386152" modified="2018-07-18" version="1">MEPQVLERMVEPFFKTQMGQGTNGLGMTIAYNIVTGIFGGQINVKMASPRGTIIEIIVPKVVLTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXN0</accession>
    <name>A0A2S9GXN0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2791</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92416">
        <property type="protein sequence ID" value="PRC92416"/>
        <property type="gene ID" value="S2091_2791"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015493994" evidence="2">
        <location>
            <begin position="20"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="122"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="134"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="162" mass="18746" checksum="4B113F2C0CF332EC" modified="2018-07-18" version="1">MKRLLLATLLAASPLLSMAQVSVGVNLNIGDPNFYGQVDLENGPPPPVMYSTPVVVQPAPPGVYYPPVYLRVPTVYYQNWPQYCGMYNACYQPVFFVQENWYMHVYAPMYRSRYPHGRPGFAPRAFYNQHGGPGPRVEERRDEHGGQRHEDRHEEHREEDHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXR9</accession>
    <name>A0A2S9GXR9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2884</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92509">
        <property type="protein sequence ID" value="PRC92509"/>
        <property type="gene ID" value="S2091_2884"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="411" mass="46757" checksum="9DB135086D9C8D3B" modified="2018-07-18" version="1">MRTLIDAVNIMRDIPHVELGAAVKHVAVIVASPRSGSSLVTKVLSSHSDIASMDGEIEPFLSLTGNGFGFNSDSDALSVLSNLSELVDNIFDNLTVLADKASPTQLKKQWAKRLVMQFPAKFSDLNQHQKLLQALDVTLTQDCVNRYPQERHLQHHVLSRIFSDEPWRMAYYDGEKKVGAGRYFDEAFKIEEPPFVVPRRNRRPFSDGDADKKMLLFKTSTDVYRVGMYEQLFPNADIKYIHLTRGYAQTVNGLMDGWLSPVGFFSHNLGQTGFKLNIKGYSDAVPFGKNWWKFDLPPNWRNYIGAHLEDICLNQWISSHREFLNTGVPALQIAFESFLMDPTATVRRITNYLGLASLQVPEALPVTMATEMPGTTRWKRREDQLMQLGTRLEVRSMMDTLGYTMNSERWI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXT5</accession>
    <name>A0A2S9GXT5_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 7">UDP-glucose 6-dehydrogenase</fullName>
            <ecNumber evidence="4 7">1.1.1.22</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">S2091_2590</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>H2O + 2 NAD(+) + UDP-alpha-D-glucose = 3 H(+) + 2 NADH + UDP-alpha-D-glucuronate</text>
            <dbReference type="Rhea" id="RHEA:23596"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58052"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="EC" id="1.1.1.22"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Nucleotide-sugar biosynthesis; UDP-alpha-D-glucuronate biosynthesis; UDP-alpha-D-glucuronate from UDP-alpha-D-glucose: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.22" evidence="4 7"/>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92535">
        <property type="protein sequence ID" value="PRC92535"/>
        <property type="gene ID" value="S2091_2590"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00038">
        <property type="reaction ID" value="UER00491"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003979">
        <property type="term" value="F:UDP-glucose 6-dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000271">
        <property type="term" value="P:polysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006065">
        <property type="term" value="P:UDP-glucuronate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017476">
        <property type="entry name" value="UDP-Glc/GDP-Man"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014027">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036220">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014026">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001732">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028357">
        <property type="entry name" value="UDPglc_DH_bac"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00984">
        <property type="entry name" value="UDPG_MGDP_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03720">
        <property type="entry name" value="UDPG_MGDP_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03721">
        <property type="entry name" value="UDPG_MGDP_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF500134">
        <property type="entry name" value="UDPglc_DH_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000124">
        <property type="entry name" value="UDPglc_GDPman_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00984">
        <property type="entry name" value="UDPG_MGDP_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52413">
        <property type="entry name" value="SSF52413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03026">
        <property type="entry name" value="NDP-sugDHase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 10" id="KW-0520">NAD</keyword>
    <keyword evidence="5 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UDPG_MGDP_dh_C" evidence="11">
        <location>
            <begin position="325"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="9">
        <location>
            <begin position="156"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="9">
        <location>
            <begin position="260"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="8">
        <location>
            <position position="271"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="30"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="35"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="86"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="121"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="159"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="215"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="268"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="274"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="332"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="339"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR000124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR500134-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR500134-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR500134-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PRC92535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="459" mass="50017" checksum="3B2C8522FF7C33A8" modified="2018-07-18" version="1">MKITIIGTGYVGLVTGACLAELGNDVLCLDLDANKVAILNNGGIPIHEPGLDVIVAANRANGRLKFTTDVAASVAHGDIQFIAVGTPPDEDGSADLQYVLAAAKNIGKYMQGFKVVIDKSTVPVGTAEKVSKVIAAELSQRNAKECSFSVVSNPEFLKEGAAVEDFMRPDRIVIGSDNDAVGLHAKALVKQLYTPFNRNRERTYWMDVRSAEFTKYAANAMLATRISFMNELANLADCVGVDIEAVRHGIGSDPRIGHSFLYAGCGYGGSCFPKDVQALERTAREYDQDLLILRAVESVNDNQKQVLGKKIIARFGENLAGHHFALWGLAFKPNTDDMRAASSRVLLRELLSRGATISVHDPVAMDEARRVLALDFADQPEQLARITYVSNPMDATNKADALLIVTEWKAYRSPDFSQLKSQLKNPIIFDGRNLFDPQDMTDLGIEYHGIGRSVLTQAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXU8</accession>
    <name>A0A2S9GXU8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">AhpC/TSA family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2906</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92531">
        <property type="protein sequence ID" value="PRC92531"/>
        <property type="gene ID" value="S2091_2906"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016209">
        <property type="term" value="F:antioxidant activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000866">
        <property type="entry name" value="AhpC/TSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
        <property type="entry name" value="AhpC-TSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015721389" evidence="1">
        <location>
            <begin position="25"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="2">
        <location>
            <begin position="21"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="167" mass="19201" checksum="5DF80F23BF1B2A01" modified="2018-07-18" version="1">MLRRNFIQSGLMVGLSMSSGLSLADTAPAPFVLQGTEISGKRLDLRDFSGLTVLVSFFTYDCDVCTDDLKLMREFYFNNRKKKFMLLGVNLDTNKKDLDDYNELTTQAYPKDQRFPTVWRNAAGHKDNFGNISVKPTHFVLDSKAQLKFKREGKFQPEDWDNLWLAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GY36</accession>
    <name>A0A2S9GY36_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2692</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92637">
        <property type="protein sequence ID" value="PRC92637"/>
        <property type="gene ID" value="S2091_2692"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="55" mass="5563" checksum="8DE5E8366574F9AE" modified="2018-07-18" version="1">MKNNTIHKLKIIAAGALIGSVLTGTFLGWVALPFDLHVIGAAIGGVVGAVQSHLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GY63</accession>
    <name>A0A2S9GY63_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2714</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92659">
        <property type="protein sequence ID" value="PRC92659"/>
        <property type="gene ID" value="S2091_2714"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="71" mass="8289" checksum="DC7D236EE9A72B45" modified="2018-07-18" version="1">MAMESWMYGDPETVAIRRQQAELSKQRACGACVHKVSVEWNGVMYHGCEFKRRVFGNRCELYRVKQETACQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYE2</accession>
    <name>A0A2S9GYE2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SIR2-like domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2463</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92733">
        <property type="protein sequence ID" value="PRC92733"/>
        <property type="gene ID" value="S2091_2463"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039444">
        <property type="entry name" value="SIR2-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13289">
        <property type="entry name" value="SIR2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SIR2_2" evidence="1">
        <location>
            <begin position="117"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="330" mass="37330" checksum="7692281E7A47F71C" modified="2018-07-18" version="1">MSHLLLLGAGFSRNWGGWLAGEAFEYLLGCPEVACNSHLQQLLWRNQPAGGFENALAEVQANFIKSPQEHTKNLQDIQNAVTRMFEDMNRGFLEHPDFEFQQARERMVGTFLTRFNAIFTLNQDLLLEHYYIDQNITLLSNGRWTGSDLPGMRPAPSGGTAIPNSWAERSWTPSSEDFNLAERMQPYFKLHGSSNWKEKHGAPMLIMGGNKIREIGLSPVLLWYHQKFEECLNKPNAKLFVIGYGFRDKHINEVIIRAINENGLKMFVIAPEGGDLARIANPTHTASIRVETSLEVAFEHGLIGASRRQLSDIFGGDTIEFNKVMRFFGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYF4</accession>
    <name>A0A2S9GYF4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">TraM recognition site of TraD and TraG</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2471</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92741">
        <property type="protein sequence ID" value="PRC92741"/>
        <property type="gene ID" value="S2091_2471"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032689">
        <property type="entry name" value="TraG-D_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12696">
        <property type="entry name" value="TraG-D_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TraG-D_C" evidence="1">
        <location>
            <begin position="96"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="270" mass="30199" checksum="A4525D1FE252EAAD" modified="2018-07-18" version="1">MAKDDLNLADVFERRQGTMTDAEKFEGKLRELAELPSINAQNGHGISLQKIIEEGGCLYIVGSMRNDIVKTVQRILLIRLIQIAERRDRISGAPRPVCIILDEVKYHLSRPALEALGTARDKGVHMVLAHQSIGDLRDCTKDLNPDAVVDAIVENCRVKICYRVQNPETAQWLSDMTGNILVDDETRYIERNLGQADIVRGERSIRQAERNLVDVNMFLNLPKGSAVVLGDGSTKFVSVRPIKTQKDASSIRFREVQGTKLHCAEAKIDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYF5</accession>
    <name>A0A2S9GYF5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2468</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92738">
        <property type="protein sequence ID" value="PRC92738"/>
        <property type="gene ID" value="S2091_2468"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="74" mass="8566" checksum="530E9BC8C2899BE0" modified="2018-07-18" version="1">MKSTLDKLQEKRSKLESQILAAKEAERRKAKAINFLSLLIDRFPESVQKNEKLFHEKLEHLMTDLASDVQRGGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYG1</accession>
    <name>A0A2S9GYG1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2489</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92759">
        <property type="protein sequence ID" value="PRC92759"/>
        <property type="gene ID" value="S2091_2489"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002197">
        <property type="entry name" value="HTH_Fis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02954">
        <property type="entry name" value="HTH_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01590">
        <property type="entry name" value="HTHFIS"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="6"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="178" mass="19724" checksum="19C97CA7B0D2FCEB" modified="2018-07-18" version="1">MTSNRLLLIIEDDAAFSRTLARSFERRGYTVICAANLEQAKALLQEHTPNYAVVDLQLHGHTSGLSCVQMLHNHDAAMLIVVLTGFASIGTAVEAIKLGACQYLAKPSNTDDIEAAFGHVAGSAEIELTNRVSSIKTLEWERIHEVLTETNFNISEAARRLGMHRRTLARKLEKQRVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYJ1</accession>
    <name>A0A2S9GYJ1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Gram-negative porin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_2511</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92781">
        <property type="protein sequence ID" value="PRC92781"/>
        <property type="gene ID" value="S2091_2511"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046930">
        <property type="term" value="C:pore complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015288">
        <property type="term" value="F:porin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006811">
        <property type="term" value="P:ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00342">
        <property type="entry name" value="gram_neg_porins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033900">
        <property type="entry name" value="Gram_neg_porin_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023614">
        <property type="entry name" value="Porin_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13609">
        <property type="entry name" value="Porin_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0406">Ion transport</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0626">Porin</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1134">Transmembrane beta strand</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015596780" evidence="4">
        <location>
            <begin position="21"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="domain" description="Porin_4" evidence="5">
        <location>
            <begin position="10"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF13609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC92781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="377" mass="39864" checksum="FC64B65807B8A850" modified="2018-07-18" version="1">MKKNVLFTLIAMLAASSAFAQQSPVTVYGLIDAAFRSGNNYETGVGNAVGTQTGLNQGALHGSRLGFKGDEDLGGGTSVVFDVEMGLVIYNGTSDQQGQLFGRQAYVGLKNKEWGELYAGRQNGLAFDIYKNYDPIGVGNSNEDSWEDTLWGLRFDNTLKYKNSWGPVKAEVQYTAGGAAGSTTIGTTDALALTYATGPFSASVLDQHSTDANSKVLNVVGFGSSFVVGPTTLLLDYFTAKRDAGFAKAASLSGGSLANTSLMGNAGNTLQRTDSVWTAGLMFKPTPVMVYTVGYMTDNVTNDSSTGNSGKVSTGYGLVEYYVTKRTEFYGMVDYTKVSGGEIDNGTQTNTVLQFSDIALGGNTSRTGFTVGICTKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYM4</accession>
    <name>A0A2S9GYM4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="13">NHLM bacteriocin system ABC transporter, peptidase/ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">S2091_2530</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92800">
        <property type="protein sequence ID" value="PRC92800"/>
        <property type="gene ID" value="S2091_2530"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022514">
        <property type="entry name" value="NHPM_micro_ABC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005074">
        <property type="entry name" value="Peptidase_C39"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="PTHR24221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03412">
        <property type="entry name" value="Peptidase_C39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="SSF90123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03796">
        <property type="entry name" value="NHLM_micro_ABC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50990">
        <property type="entry name" value="PEPTIDASE_C39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 8 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-1278">Translocase</keyword>
    <keyword evidence="2 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="176"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="212"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="291"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="317"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="397"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase C39" evidence="12">
        <location>
            <begin position="27"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="11">
        <location>
            <begin position="179"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="496"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="530"/>
            <end position="537"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PRC92800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="730" mass="80505" checksum="95B8A605428A167E" modified="2018-07-18" version="1">MINFRQLAMTLRTKFSKQRSKTPLIFQLEAVECGAASLAMILAHYKKYLSLEELRVSCGVSRNGSRASHIVNAARKYGLLATGFRKEPAELRTMSLPMIIFWNFNHFVVVDGFEGDTVLVNDPGLGRRRIDAEEFDQSFTGIVLAFEKGPAFVPSGRPPNLFRSLRQRLGGTRQGLIYLILIGLSLVIPGLVIPIFSSVFIDRVLIGGLQSWLFPLLSGMLLTSVLLALLTWLQKYYLIKLDAKIALSTSARFFWHVLRLPVGFYQQRSAGDIGSRLAISERIANILSEDLVGAVLSLMTATFFASMMLFYDVSMTLVTVAVVLLNVVVMRFVAVRQIELNQRMAIDRGKVIGTSMNGLRLIETLKASGSESDFFTRWAGYQARLTNSMQQMNRTSIILNLIPKFLTGVSSIFILGIGGMRVMQGGMSIGMLVAFQALAQSFVNPVNALVALSGKMQGFQGDMDRLDDVMRSPVENITAVEENAENLLCAKLEGHLELRNVTFGYSRLEPPLLKNFSLTLQPGQRIALVGASGCGKSTVSKLVIGLCEPWEGSILFDGKPRNAWPRQQLLNSVAAVDQDICIFSGTVRENLNMWDTTIPHKVVVDAARDACVHDVISSRPGGYDSVVAEGGGNFSGGQRQRLEIARALSSNPRLLILDEATSALDPLTEKIVENNLRRRGCSCLVVAHRLSAIRDCDEIILLDKGVVMERGSHQDLIELNGHYARLISNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYM5</accession>
    <name>A0A2S9GYM5_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Phosphatidylserine decarboxylase proenzyme</fullName>
            <ecNumber evidence="11">4.1.1.65</ecNumber>
        </recommendedName>
        <component>
            <recommendedName>
                <fullName evidence="11">Phosphatidylserine decarboxylase alpha chain</fullName>
            </recommendedName>
        </component>
        <component>
            <recommendedName>
                <fullName evidence="11">Phosphatidylserine decarboxylase beta chain</fullName>
            </recommendedName>
        </component>
    </protein>
    <gene>
        <name evidence="11" type="primary">psd</name>
        <name evidence="12" type="ORF">S2091_2557</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-L-serine + H(+) = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + CO2</text>
            <dbReference type="Rhea" id="RHEA:20828"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57262"/>
            <dbReference type="ChEBI" id="CHEBI:64612"/>
            <dbReference type="EC" id="4.1.1.65"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>pyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
        </cofactor>
        <text evidence="11">Binds 1 pyruvoyl group covalently per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Lipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="11">Phospholipid metabolism; phosphatidylethanolamine biosynthesis; phosphatidylethanolamine from CDP-diacylglycerol: step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cell membrane</location>
            <topology evidence="11">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="11">Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.</text>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.65" evidence="11"/>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92827">
        <property type="protein sequence ID" value="PRC92827"/>
        <property type="gene ID" value="S2091_2557"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00068">
        <property type="reaction ID" value="UER00113"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00558">
        <property type="reaction ID" value="UER00616"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004609">
        <property type="term" value="F:phosphatidylserine decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006646">
        <property type="term" value="P:phosphatidylethanolamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00662">
        <property type="entry name" value="PS_decarb_PSD_B_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003817">
        <property type="entry name" value="PS_Dcarbxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033177">
        <property type="entry name" value="PSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033178">
        <property type="entry name" value="PSD_type1_pro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10067">
        <property type="entry name" value="PTHR10067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02666">
        <property type="entry name" value="PS_Dcarbxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00163">
        <property type="entry name" value="PS_decarb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 11" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 11" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="3 11" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="5 11" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8 11" id="KW-0456">Lyase</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 11" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="9 11" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="10 11" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11" id="KW-0865">Zymogen</keyword>
    <feature type="chain" id="PRO_5023487557" description="Phosphatidylserine decarboxylase beta chain" evidence="11">
        <location>
            <begin position="1"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023487558" description="Phosphatidylserine decarboxylase alpha chain" evidence="11">
        <location>
            <begin position="248"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system; for autoendoproteolytic cleavage activity" evidence="11">
        <location>
            <position position="88"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system; for autoendoproteolytic cleavage activity" evidence="11">
        <location>
            <position position="145"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system; for autoendoproteolytic cleavage activity" evidence="11">
        <location>
            <position position="248"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity" evidence="11">
        <location>
            <position position="248"/>
        </location>
    </feature>
    <feature type="site" description="Cleavage (non-hydrolytic); by autocatalysis" evidence="11">
        <location>
            <begin position="247"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="modified residue" description="Pyruvic acid (Ser); by autocatalysis" evidence="11">
        <location>
            <position position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PRC92827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="281" mass="30608" checksum="93478AC5444E1138" modified="2018-07-18" version="1">MPDSLSILLQHLLPKQALTEFGAHIANAKAGRITTGIIRWFVKKYGVNMAEALNSDISSYASFNEFFTRPLKPGARPLASADFICPVDGAISQFGAIAQDQIFQAKGHQFSTTALVGGDAQLAAQFHNGSFANIYLSPKDYHRIHMPCDGRLTRMIYIPGDLFSVNPVTAQGVPNLFARNERVVCVFESENGPFVLTLVGATIVGSMATVWHGVVNPPRTKEVREWTYDAQNITLKKGEEMGQFLLGSTVVMLFPTNTLSFNKAWQPAAKVCLGVAMGSLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYT6</accession>
    <name>A0A2S9GYT6_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Type II secretion system protein I</fullName>
            <shortName evidence="5">T2SS minor pseudopilin I</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_2277</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Type II secretion is composed of four main components: the outer membrane complex, the inner membrane complex, the cytoplasmic secretion ATPase and the periplasm-spanning pseudopilus.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell inner membrane</location>
            <topology evidence="5">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="5">Cleaved by prepilin peptidase.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the GSP I family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92860">
        <property type="protein sequence ID" value="PRC92860"/>
        <property type="gene ID" value="S2091_2277"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015627">
        <property type="term" value="C:type II protein secretion system complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015628">
        <property type="term" value="P:protein secretion by the type II secretion system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003413">
        <property type="entry name" value="T2SS_GspI_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010052">
        <property type="entry name" value="T2SS_protein-GspI"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38779">
        <property type="entry name" value="PTHR38779"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02501">
        <property type="entry name" value="T2SSI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01707">
        <property type="entry name" value="gspI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0488">Methylation</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="T2SSI" evidence="6">
        <location>
            <begin position="45"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU368030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC92860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="127" mass="13896" checksum="BD9D588D9493CE72" modified="2018-07-18" version="1">MLTMPSKKQAGFTLLEVLVALVIVGVALGASLRAVGSLTQNSNHLRASMMATWSAENRLSQIRLSTTWPDVGQSNFPCPQGDLPLVCLQEVIATPNPSFRRVEVSVVDERFPERRIIKLTQVVPNAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZ53</accession>
    <name>A0A2S9GZ53_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative redox protein regulator of disulfide bond formation</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92983">
        <property type="protein sequence ID" value="PRC92983"/>
        <property type="gene ID" value="S2091_2400"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003718">
        <property type="entry name" value="OsmC/Ohr_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036102">
        <property type="entry name" value="OsmC/Ohrsf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02566">
        <property type="entry name" value="OsmC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82784">
        <property type="entry name" value="SSF82784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="134" mass="14652" checksum="6299E81A007BC07F" modified="2018-07-18" version="1">MSIELKRIKNTATAQIVSIGQHRLTVDMSIAEGGLDEGPNPHDLYDAALGACKALTVLWYANKKGIPVDDIRTSIQRDNSSEKTGTYRLAATVHVSGDLSDEQIKELEMIAGKCPIHKLMTTVNTEITSVVERM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZ63</accession>
    <name>A0A2S9GZ63_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2405</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92988">
        <property type="protein sequence ID" value="PRC92988"/>
        <property type="gene ID" value="S2091_2405"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="65" mass="7550" checksum="61C496E974A60A7C" modified="2018-07-18" version="1">MENPKTNVVVDGRNVQVVEALFLMRDHLLDLSDALQNLLFELDLQGRNEVEMSTNKLLQRLKQQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZD3</accession>
    <name>A0A2S9GZD3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phage minor tail protein L</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2181</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93095">
        <property type="protein sequence ID" value="PRC93095"/>
        <property type="gene ID" value="S2091_2181"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030430">
        <property type="term" value="C:host cell cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046718">
        <property type="term" value="P:viral entry into host cell"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006487">
        <property type="entry name" value="Phage_lambda_L"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05100">
        <property type="entry name" value="Phage_tail_L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01600">
        <property type="entry name" value="phage_tail_L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="230" mass="24762" checksum="2DAD79EBCEA1A552" modified="2018-07-18" version="1">MIKSDAQLLEVGEVVVLFELDATQIGGNYLKFHGYQEIGAITWQGKEYTAWPILAEGFARTSAQQPAPTLAVGNVDGAISALCIHFDDLVGAKLTRHTTLGKYLDAVNFSEGNPSADPSQEFPVDVWTIEQKTSETSEAVEFELASALNFQGTQLPRRQIVANVCTWLSTGGYRGTYCGYTGAAMFDKDGNPVASSALDRCGGKLSDCKKRFGENNILNFGSFPAAGMLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZF4</accession>
    <name>A0A2S9GZF4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2173</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93087">
        <property type="protein sequence ID" value="PRC93087"/>
        <property type="gene ID" value="S2091_2173"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="39" mass="3841" checksum="E568B61F5C7AF7CA" modified="2018-07-18" version="1">MSVTVPNGTEFAIAGSYAAAVPITKISNAAIAIFSAANT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZM4</accession>
    <name>A0A2S9GZM4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2152</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93066">
        <property type="protein sequence ID" value="PRC93066"/>
        <property type="gene ID" value="S2091_2152"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="84" mass="9573" checksum="D23A824B90F9942F" modified="2018-07-18" version="1">MNRTYYSTRRKFICFISDWLGTFLLALVGLFVCSYVDNQYQDEILSASVAEEARQQVAKEASEDQQARLQLTAQAEYMTGFGAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZR5</accession>
    <name>A0A2S9GZR5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Rhodanese-related sulfurtransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1967</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93229">
        <property type="protein sequence ID" value="PRC93229"/>
        <property type="gene ID" value="S2091_1967"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004792">
        <property type="term" value="F:thiosulfate sulfurtransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001307">
        <property type="entry name" value="Thiosulphate_STrfase_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="SSF52821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00380">
        <property type="entry name" value="RHODANESE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Rhodanese" evidence="1">
        <location>
            <begin position="39"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="133" mass="14485" checksum="E3727C527EE85E20" modified="2018-07-18" version="1">MSIVTEVVAAQSELALTHFSSIFQFETDCWDVHHALTTGNPDFVLLDVRGPDHFAAGHIPGAQHLPHGKIIEMKLAHYPSDTIFVTYCAGPHCNGAARAAIRLARLGRPVKVMPGGITGWLDEGFVLETRVQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZT2</accession>
    <name>A0A2S9GZT2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Peptidase family M1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1983</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93245">
        <property type="protein sequence ID" value="PRC93245"/>
        <property type="gene ID" value="S2091_1983"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014782">
        <property type="entry name" value="Peptidase_M1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027268">
        <property type="entry name" value="Peptidase_M4/M1_CTD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01433">
        <property type="entry name" value="Peptidase_M1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="101"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="146"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="176"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="244"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="324"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="365"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="404"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="449"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="477"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="523"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="566"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M1" evidence="2">
        <location>
            <begin position="868"/>
            <end position="1052"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="1202" mass="136632" checksum="E0EE78E364C4CF25" modified="2018-07-18" version="1">MWKEFFKFDLRYQLRQPLLWVVAFVLAALAFGAATSDEITVGSAIGNVNRNAPVVIVQFLAMFSQLSMFVVTIFIAGAVLRDSEIGISDMIFATPMRKLDYLMGRFLAGMGACLMIFLIISIGIMLGPLMPWVDSARVGPFLIQPFIYGIVIFVLPNLLFMSGLLMLLAATTRSIIYVYVGVIAFFVLSIMARVLTRDVNNEWLASLIDPFGMSAFGRMTRYFTVQESNTILPSVSNYLLVNRLLWSAVALLMFAATVFLFKPQRAGTGRRWFGKAVVKTAEEPGVIVSTVEHMQVDVVFSPSTAWKQCWSILFFDAKAIFKSAPFLVILMFGMMNFIAGASLGGKLYGTNFYPVTRQMLETLSGSFNFLLIVIVTFYAGELIFKERQAKIAEVINAMPMPNWVPLAAKCTALVGIVISFMTVGALVGMCIQLVKGGTTIEGLLYVKGVLLGAMPFVLMGLFAIGVQVIFNNKFIGYLLMILLFVSLMLTGMMHFEHNLYNFAGLPAIQYSDMNGYGHFLTGWSWFAVYWSLFVVALLIIAAAFWERTLSPDWRARMRLAVLRLKAGSGIALALSLSGFAMTGAWIFYNTNVLNKYIPSDVEMDNQASYEKNYRQYKDLPQLKVIDVKAEVDIFPAERRVAIQGHYVLQNKTALPLDTLRIQHDPRFETKWLNLPQHQTTLEDKELGFMIVKLAQSIAPGANLALDFSVSDTHQGFTNSGKPDRVNLNGTFISSDMYFPHFGYSTNMEMQDRYERRKRGLGEPDRANKLENVAALVNHVGGQDSDWVNFDTTVSTSADQIALAPGYLQKTWTENGRRYFHYKMDKPGLFFFSYQSANWEVKKGDWHGMPIEIYYDKKHPYNVDRMIYATQKSLDYYTQQFTPYEHHQVRILEFPRYERFAQSFANTVPFSEEIGFIADLRNKDDIDYVYYVTAHEVAHQWWAHQVIGADVQGATMLMESMAQYSALMVMEKEYGREKMRRFLRQELDTYLQGRGGEKIEELPLNRVENQPYIHYRKGALIFYRLRDEIGEEPLNRALKRYLQDKAFQQAPYTTSLELLDYIRAETPPEKQALITDLFEKIVIYDNRVTEATTVHRPDGQWDVTMKLHLAKMEVDGKGKETPRIYDEPAEIAVFSRAKGADEKDEKVLYIAKRVLQGSDPVVTVTVKEQPFEVGVDPYNKLIDRVPGDNRKEVSLNEDGVKLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H016</accession>
    <name>A0A2S9H016_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Serine-type D-Ala-D-Ala carboxypeptidase</fullName>
            <ecNumber evidence="4">3.4.16.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">S2091_2031</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the peptidase S11 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.16.4" evidence="4"/>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93293">
        <property type="protein sequence ID" value="PRC93293"/>
        <property type="gene ID" value="S2091_2031"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009002">
        <property type="term" value="F:serine-type D-Ala-D-Ala carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.410.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015956">
        <property type="entry name" value="Peniciliin-bd_prot_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018044">
        <property type="entry name" value="Peptidase_S11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012907">
        <property type="entry name" value="Peptidase_S11_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037167">
        <property type="entry name" value="Peptidase_S11_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001967">
        <property type="entry name" value="Peptidase_S11_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07943">
        <property type="entry name" value="PBP5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00768">
        <property type="entry name" value="Peptidase_S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00725">
        <property type="entry name" value="DADACBPTASE1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00936">
        <property type="entry name" value="PBP5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69189">
        <property type="entry name" value="SSF69189"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 17" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="9" id="KW-0133">Cell shape</keyword>
    <keyword evidence="11" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="6" id="KW-0645">Protease</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 15" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="15">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015466629" description="Serine-type D-Ala-D-Ala carboxypeptidase" evidence="15">
        <location>
            <begin position="37"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="domain" description="PBP5_C" evidence="16">
        <location>
            <begin position="292"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-ester intermediate" evidence="12">
        <location>
            <position position="73"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="12">
        <location>
            <position position="76"/>
        </location>
    </feature>
    <feature type="active site" evidence="12">
        <location>
            <position position="135"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="238"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR618044-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR618044-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU004016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="SMART" id="SM00936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="PRC93293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="398" mass="44099" checksum="67EEC0FB0B044499" modified="2018-07-18" version="1">MSQSVFVFYLVLNQSIMKKLLALSLLCLAVFSSAQAQTMPAPTIAAKSWLLLDTTSNQIIASENPEMRIEPASLTKIMTAYLVFEALRDKKVTMEQLVNVSVKAWKVDSDSSKMFIEPKTPVTVNDLLYGLIVQSGNDAAVALAETVAGSEEAFAVLMNREVERMGLKATHFANPHGLPDPQNYSTAQDLARIAQHLIVEFPEYYKTFYSTKSFTYNKITQPNRNRLLWLDPTVDGMKTGHTAAAGFCLVSSAKRPNGTGERRLISVVLGATSDQVRAQESLKLLNWGFLNFDTVKLYEKNQAIDTPEIWKGTQAKIKIGFTDDLYVTLPKGSAARIKPQLERKDPLVAPIAANAKIGTMKMMIDGKPVAEFPVMALETVNQASIFGRAWDSIRLWLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H019</accession>
    <name>A0A2S9H019_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1954</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93216">
        <property type="protein sequence ID" value="PRC93216"/>
        <property type="gene ID" value="S2091_1954"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021994">
        <property type="entry name" value="DUF3592"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12158">
        <property type="entry name" value="DUF3592"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="124"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="149" mass="16420" checksum="2EAE97C1BC2AC9DB" modified="2018-07-18" version="1">MLKNLALPILIFVLLGLFGLSLSKDGYSAYRSQSWPAVDGVVTQSDWSHHRGKGCNYGLLFTYNYSVSGNFYAGRNYRFGGECGSDVKQIVSTHPVGSKVHVFYKPDSPDESVVSPGDISGDTWTSLIITPLLMLLCVFLAMISFKARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H026</accession>
    <name>A0A2S9H026_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_2041</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93303">
        <property type="protein sequence ID" value="PRC93303"/>
        <property type="gene ID" value="S2091_2041"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="178"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="8">
        <location>
            <begin position="199"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="7">
        <location>
            <begin position="259"/>
            <end position="476"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC93303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="476" mass="52216" checksum="375078914A520E14" modified="2018-07-18" version="1">MLATLSFRQLLLAGFLLIAVLLSGTSVQALLTIGHLATQSRTVAHQAVALTAETQRLAERTVAMERSARQYMVLDDPAFRALFLSALQDARASLQLVVQAAPGLPTQPVAKWLQQSALAWDMMQDAPDRAALKKQQQALYSALVNLSEINDQLALASKREIERSNEAALSELEQQRRLLIGLVSGAILLAILLALSFGVWLSRPLAQIEVIIERLGENKFDQSIVIHGPADMRKLGLQLDWLRQRLGNLEDDKSRFLRHISHELKTPLAALREGVALLKDEVVGTLTEPQREIARILSQNSASLQIQIEDLLRYNTAVFDARQVQLSRVNLPELLTSVIQDQRLQWQARSLQITVVPGTVTEIDADAGKLSIVLANLLTNAVRFSPVGGVIQFVLAAKAQAVQIDCIDQGPGIAAEDTKHIFEPFYQGARQMPGARSGNGIGLSIVVEYIAAHDGNVQLLPVSAGAHFRIELPYEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H121</accession>
    <name>A0A2S9H121_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_1658</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93657">
        <property type="protein sequence ID" value="PRC93657"/>
        <property type="gene ID" value="S2091_1658"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="16"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="167"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="8">
        <location>
            <begin position="196"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="7">
        <location>
            <begin position="254"/>
            <end position="469"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC93657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="469" mass="52234" checksum="38F23BC6E87E9DF4" modified="2018-07-18" version="1">MKNTLLEHWRVSTFRLAMLFGVLFIIGNVALLNLIYWQTSSYLVHRIDDSIYTMSANFKNLSPEKVLIQVNDALEYDLRKSNLYGLFSADKKVISGNMDSFPNGLSVDGKIHQFAHRGISPYLPNGAAPADVTNSNIGLARALVQRLPNNDILIIGRDFTQLAEIKAIILNALIGSGAVILFIGLLSGFALSLSPLRRINAIRTTSRRIMQGELSMRMPVSNRHDELDMLATIVNTMLEEIERLLTEVKSVTDTLAHDLRTPLTRLRLMLYRAQQQLPSDNPQHYLLENALTETDALLGRFRALLRISEIENRHRKSGFKSINPSDVLHQLIELFEPLAEDASVTLSLQCDATDNIDADPDLLFEAISNLVDNAIKFTPVGGSVLIQLSQPNDTPRIDIIDTGCGIPIAEREAVLLRFHRSNQPGLHQEKEGYGLGLSIVAAVVRLHGFSLQFQEAETGTHLTVLCTRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H175</accession>
    <name>A0A2S9H175_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Glutamate synthase domain 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_1617</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the glutamate synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93616">
        <property type="protein sequence ID" value="PRC93616"/>
        <property type="gene ID" value="S2091_1617"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015930">
        <property type="term" value="F:glutamate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006537">
        <property type="term" value="P:glutamate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02808">
        <property type="entry name" value="GltS_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024188">
        <property type="entry name" value="GltB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002932">
        <property type="entry name" value="Glu_synthdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027283">
        <property type="entry name" value="YerD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01645">
        <property type="entry name" value="Glu_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006429">
        <property type="entry name" value="GOGAT_lg_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF500060">
        <property type="entry name" value="UCP500060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="5"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="31"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="domain" description="Glu_synthase" evidence="4">
        <location>
            <begin position="155"/>
            <end position="477"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR006429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC93616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="541" mass="59524" checksum="DB21159D23F2F9B1" modified="2018-07-18" version="1">MQNLFLRYTTLLLSGAIFIFSLLFFNVHESISWLLVISAALICIGVHDIIQTKSSILRNYPILAHFRFLFELIRPEIRQYFLEEDTSPNPFSRNQRSIVYQRAKQQLDKRPFGTQLDVYQAGYEWIGHSITPAPITTHDFRITIGADRAQPYSASIFNISAMSFGALSANAIRALNQGAHKGNFMHDTGEGSISRYHRPENEHEQGGDLVWNIGSGYFGCRNPDGSFSEEKFTANANLPQVKMIEVKLSQGAKPGHGGLLPGSKVSAEIAKARGVTEGVDCVSPSSHSAFSTPIELLQFIEKLRTLSGGKPTGFKFAVGHPWEFFGIVKAMLVTGIHPDFIVVDGGEGGTGAAPVEFTDHVGVPLQEALLLVHNTLVGCNLRDKVKIGASGKIITAFDITRTLALGADWCNSARGFMFALGCIQSQSCHTDRCPTGVATQDPLRQRALFVPDKAERVFHFHDNTLKAMSELIAAAGLTHPNQLRPHHLVRRVSPDQVRLVSSLLPYLATGQLLEPVQLQGLPDVYATYWPIAQAESFHPIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H184</accession>
    <name>A0A2S9H184_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Asparaginase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_1745</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93744">
        <property type="protein sequence ID" value="PRC93744"/>
        <property type="gene ID" value="S2091_1745"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004067">
        <property type="term" value="F:asparaginase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036152">
        <property type="entry name" value="Asp/glu_Ase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006034">
        <property type="entry name" value="Asparaginase/glutaminase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027475">
        <property type="entry name" value="Asparaginase/glutaminase_AS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027474">
        <property type="entry name" value="L-asparaginase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037152">
        <property type="entry name" value="L-asparaginase_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00710">
        <property type="entry name" value="Asparaginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001220">
        <property type="entry name" value="L-ASNase_gatD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00139">
        <property type="entry name" value="ASNGLNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53774">
        <property type="entry name" value="SSF53774"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00917">
        <property type="entry name" value="ASN_GLN_ASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51732">
        <property type="entry name" value="ASN_GLN_ASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Asparaginase" evidence="3">
        <location>
            <begin position="4"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="active site" description="O-isoaspartyl threonine intermediate" evidence="1">
        <location>
            <position position="11"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR001220-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC93744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="161" mass="17413" checksum="B48A4B8240287BAE" modified="2018-07-18" version="1">MSLRILATGGTFDKHYDEIAGKLTFAKSHLPDVIARARITLPTQLEIVAMLDSLDMQDADRSNVLAACQQATEAAIVIIHGTDTMSETAHVIGNAKLAKTIILTGAMIPYEIANSDALFNLGFACGIAQALPHGVYIAMNGQIFNWDNVKKNRTQGVFIQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H192</accession>
    <name>A0A2S9H192_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative Mg2+ and Co2+ transporter CorC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_1750</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93749">
        <property type="protein sequence ID" value="PRC93749"/>
        <property type="gene ID" value="S2091_1750"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04590">
        <property type="entry name" value="CBS_pair_CorC_HlyC_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044751">
        <property type="entry name" value="Ion_transp-like_CBS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005170">
        <property type="entry name" value="Transptr-assoc_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03471">
        <property type="entry name" value="CorC_HlyC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01091">
        <property type="entry name" value="CorC_HlyC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="SSF56176"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0129">CBS domain</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="CBS" evidence="4">
        <location>
            <begin position="84"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="4">
        <location>
            <begin position="147"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC93749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="306" mass="34636" checksum="B30DE256370A49A9" modified="2018-07-18" version="1">MPEHPSNVRNAVFKTATKAASSDIKPHRSLFERLTALISPEPESRVELLEVLQDAHERNLIDADALSMIEGVFQVSDLCARDIMVPRSQMDVIDISKPIEEWMPHVISTAHSRFPAVEGNRDKVVGVLLAKDLLRYYFDEEFDVRDMLRPAVFIPESKRLNVLLRDFRANRNHIAMVVDEYGGVDGLITIEDVLEQIVGDIEDEYDFDEEEDNILSIDPGTQGARWRVKGLTEISQFNDIIGSHFSDEDVDTIGGLVANHLARVPHKGDKFAIGRISFEVLRADPRQVHVLLIERLPHSENDVDLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1B5</accession>
    <name>A0A2S9H1B5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Dioxygenases related to 2-nitropropane dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1734</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93733">
        <property type="protein sequence ID" value="PRC93733"/>
        <property type="gene ID" value="S2091_1734"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018580">
        <property type="term" value="F:nitronate monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04730">
        <property type="entry name" value="NPD_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004136">
        <property type="entry name" value="NMO"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03060">
        <property type="entry name" value="NMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NMO" evidence="1">
        <location>
            <begin position="86"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="329" mass="34650" checksum="667595EFEDB73516" modified="2018-07-18" version="1">MTQPMIKPALPLVLQNLSLPVIGSPMFIASGPKLVAAQCKAGIVGSFPALNARPAELLDVWLTDLKKELAEFQAEHPNAKVGPIAVNQIVHHSNDRLEHDVAVCVKHQVPIIISSLRAPPKEMLDAIHSYGGIVLHDVISIRHAQKALEAGVDGLILVATGAGGHAGVLSPFALVGEVRKFYQGPIALSGSIASGDAILAAQALGADFAYIGSRWLATKEANVSEEYKQAIIDSSAADIVYTNLFTGIHGNYLKKSIVSAGLDPDNLPEADKSKMNFGGGSAAKAWRDIWGAGQGVGLMNDAPDVAEVVARLKEEYQAARARLNALAAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1F4</accession>
    <name>A0A2S9H1F4_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA helicase</fullName>
            <ecNumber evidence="2">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_1421</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O = ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="2"/>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93812">
        <property type="protein sequence ID" value="PRC93812"/>
        <property type="gene ID" value="S2091_1421"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014017">
        <property type="entry name" value="DNA_helicase_UvrD-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000212">
        <property type="entry name" value="DNA_helicase_UvrD/REP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11070">
        <property type="entry name" value="PTHR11070"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13361">
        <property type="entry name" value="UvrD_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0347">Helicase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UvrD-like helicase C-terminal" evidence="5">
        <location>
            <begin position="89"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="domain" description="UvrD-like helicase C-terminal" evidence="5">
        <location>
            <begin position="205"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF13361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC93812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="282" mass="31685" checksum="78522B66ACA910D0" modified="2018-07-18" version="1">MYFEACVDRVIHSVDQKLIPSAQYDAVLIDEGHDFKPEWFKLIVQMVNPDTNSLLVLYDDAQSIYNAPKKLRFSFSSVGIQAKGRTTILKLNYRNTVEILSVARAFADDLVSSHEVEEDHAPTVQPMSAGRRGAKPLLVKLPTLKEEAEYLASALMDANKTGTSWNDIGIIYRRYAVGQQLAETLARKGIPFQWQQDKKNSYTPLHDSVKLITMHSSKGLEFPVVYIPAIGAPSKEVEEMQDEARLLYVAMTRATHQLVMTHSDESLLSEKMQKAMNVLAAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1I9</accession>
    <name>A0A2S9H1I9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">MltA-interacting protein MipA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_1429</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MipA/OmpV family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93820">
        <property type="protein sequence ID" value="PRC93820"/>
        <property type="gene ID" value="S2091_1429"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010583">
        <property type="entry name" value="MipA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06629">
        <property type="entry name" value="MipA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015696493" evidence="5">
        <location>
            <begin position="19"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC93820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="274" mass="30513" checksum="4C3FA0603CE8A94E" modified="2018-07-18" version="1">MKKIFLLLLLLAFDAAHAQTNLPNNLFIEQIQSNDSLPEHSQDNYVGVYLAEIPKYQGSTEMESELAINVHREWSNGALISINTWKPYDTYQIGMHLNSTGNLDYGVLLGVGRNRASFIDSDGGNKGKDWMPFVGGFLNYKIADDIQLSNELLYYFGQYKGGQYDDLNLIKSFAITDHQSLALSVGTVLGNQKFANTQFGISPDQSAEYGYPAYTPSAGVQDVHFGVNWRWSFSSAWTLNSSLYASHLTSNVSETKQVKNENNGSISVGLAYRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1R4</accession>
    <name>A0A2S9H1R4_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Probable protein kinase UbiB</fullName>
            <ecNumber evidence="9">2.7.-.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Ubiquinone biosynthesis protein UbiB</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">ubiB</name>
        <name evidence="11" type="ORF">S2091_1415</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 9">Cofactor biosynthesis; ubiquinone biosynthesis [regulation].</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell membrane</location>
            <topology evidence="9">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the ABC1 family. UbiB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.-.-" evidence="9"/>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93806">
        <property type="protein sequence ID" value="PRC93806"/>
        <property type="gene ID" value="S2091_1415"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00232"/>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010795">
        <property type="term" value="P:regulation of ubiquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006744">
        <property type="term" value="P:ubiquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd13972">
        <property type="entry name" value="UbiB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00414">
        <property type="entry name" value="UbiB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004147">
        <property type="entry name" value="ABC1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010232">
        <property type="entry name" value="UbiB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045308">
        <property type="entry name" value="UbiB_bact"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03109">
        <property type="entry name" value="ABC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01982">
        <property type="entry name" value="UbiB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="2 9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9" id="KW-0418">Kinase</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5 9" id="KW-0831">Ubiquinone biosynthesis</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="496"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="domain" description="ABC1" evidence="10">
        <location>
            <begin position="89"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="9">
        <location>
            <position position="283"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="126"/>
            <end position="134"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="148"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00414"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF03109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC93806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="518" mass="59429" checksum="4326B7184080E31B" modified="2018-07-18" version="1">MFRKIFRFLKIFLVTVRYGLDEIAFSSLGVGRVVRALELLLFWRDLSAPRGQRLRCALEELGPIFVKFGQVLSTRRDLMPMDIADELAKLQDRVPPFDSDLAIAQITKSLGAHPDQLFASFERIPVASASIAQVHFATLKNGREVAVKVLRPGMKKSIDQDVALMHVAASLLEWVWSDGKRLKPKEVVAEFDKYLHDELDLMREAANGSQLRRNFADSDLLLVPEMLWDYCSSSVIVMERMKGIPVSQIDQLIEAGVDLKKLSRDGVEIFFTQIFRDGFFHADMHPGNIMVSTDPATLGRYIALDFGIVGTLNDFDKDYLSQNFLAFFRRDYKRVAQAHIESGWAPKDTRVDELEAAVRACCEPIFDRPLKDISFGYVLLRLFQTSRRFNVEVQPQLVLLQKTLLNIEGLGRQLDPELDLWKTAQPYLEKWMAKQIGWEGVWQNLKIEAPHFAHIFPQLPRLMHKVLTRANDDTPPQVMEQLLKEQKNTNQLLRTIIWFVGGFLGGLVLLQLWSFFMY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1V7</accession>
    <name>A0A2S9H1V7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="8">GtrA-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_1132</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GtrA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC93959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93959">
        <property type="protein sequence ID" value="PRC93959"/>
        <property type="gene ID" value="S2091_1132"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000271">
        <property type="term" value="P:polysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007267">
        <property type="entry name" value="GtrA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04138">
        <property type="entry name" value="GtrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="39"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="73"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="101"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="domain" description="GtrA" evidence="7">
        <location>
            <begin position="14"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC93959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="125" mass="13999" checksum="5BE07F3B1752A8CC" modified="2018-07-18" version="1">MRKFFIRQRQFFVFIVGGGVCALIDIGLMQLLIAFGINYVGATSTGFLAGLLINYAFHANLTFRANTTSRRFVRYLCVVVINYLITIASVSLSMSLTETPLIGKLVSLPIIAINGYMLSKYWIFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H208</accession>
    <name>A0A2S9H208_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">7-cyano-7-deazaguanine synthase</fullName>
            <ecNumber evidence="2">6.3.4.20</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">7-cyano-7-carbaguanine synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="2">PreQ(0) synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="2">Queuosine biosynthesis protein QueC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">queC</name>
        <name evidence="3" type="ORF">S2091_1198</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>7-carboxy-7-deazaguanine + ATP + NH4(+) = 7-cyano-7-deazaguanine + ADP + H(+) + H2O + phosphate</text>
            <dbReference type="Rhea" id="RHEA:27982"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:45075"/>
            <dbReference type="ChEBI" id="CHEBI:61036"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.20"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="2">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Purine metabolism; 7-cyano-7-deazaguanine biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the QueC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.20" evidence="2"/>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94025">
        <property type="protein sequence ID" value="PRC94025"/>
        <property type="gene ID" value="S2091_1198"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00391"/>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016879">
        <property type="term" value="F:ligase activity, forming carbon-nitrogen bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008616">
        <property type="term" value="P:queuosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01995">
        <property type="entry name" value="ExsB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01633">
        <property type="entry name" value="QueC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018317">
        <property type="entry name" value="QueC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42914">
        <property type="entry name" value="PTHR42914"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06508">
        <property type="entry name" value="QueC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006293">
        <property type="entry name" value="ExsB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00364">
        <property type="entry name" value="TIGR00364"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1 2" id="KW-0671">Queuosine biosynthesis</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="9"/>
            <end position="19"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="197"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="212"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="215"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="218"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01633"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="238" mass="26642" checksum="45614878D987F8E9" modified="2018-07-18" version="1">MNSSALVLFSGGQDSTTCLAWALENYERVETLGFDYGQRHDIELVMRPILREKIAPLHPHWAERLGPDHLLDLSLISSISETAMTADIDIVMQENGLPNTFVPGRNLLFMTVAAALAYRRGIDVLVGGMCETDFSGYPDCRDDTMKALQVALNLGMNTRINLATPLMWLDKSQTWELAHKLGGTALIDLIRTETHTCYLGERGKKHDWGYGCETCPACLLRAKGYMEFIARNNIFTKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H268</accession>
    <name>A0A2S9H268_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Fatty-acid desaturase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_1242</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94069">
        <property type="protein sequence ID" value="PRC94069"/>
        <property type="gene ID" value="S2091_1242"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016717">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03505">
        <property type="entry name" value="Delta9-FADS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015876">
        <property type="entry name" value="Acyl-CoA_DS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11351">
        <property type="entry name" value="PTHR11351"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="35"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="89"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="179"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC94069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="329" mass="37799" checksum="71FE7000C4E9DF94" modified="2018-07-18" version="1">MKSTPASLDNHRASSNSITCATIGNVHYSPVKSLWFLGMAGAAIVGGIFTFSWAGLILFVISTGIVLLLGHSLGSHRKLIHNSYQCPKWLEFFFVYLGVLVGLAGPLGLLRQHELRDYAQRLPNCHDYLRHGRSFWADGWWQIHCELELTNPPEIRIESSILNQRFYQFLEYTWMWQQLPIAILFYCWGGWGFVFWGVCARVTAGIFGHWLIGYFAHNHGGMHYEVRDAAVQGRNIHLTSLLTMGECWHNNHHAYPGSARLGIHSGEWDPGWWVLVALRRIGLVWNIRLPDDLPVRTELVELRSDMPTDLNIKNKADRCWIQARLYFKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H270</accession>
    <name>A0A2S9H270_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1255</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94082">
        <property type="protein sequence ID" value="PRC94082"/>
        <property type="gene ID" value="S2091_1255"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="65" mass="7211" checksum="E0C3FF4959467069" modified="2018-07-18" version="1">MIVHFRGDAPLSRLTVFPEKGQQHLMAGKIAWFDVNVNVKLNGDCAALSAGMIVHIRCVMQVEVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2C8</accession>
    <name>A0A2S9H2C8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Siderophore-interacting protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1276</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94103">
        <property type="protein sequence ID" value="PRC94103"/>
        <property type="gene ID" value="S2091_1276"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013113">
        <property type="entry name" value="FAD-bd_9_SIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007037">
        <property type="entry name" value="SIP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039374">
        <property type="entry name" value="SIP_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30157">
        <property type="entry name" value="PTHR30157"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08021">
        <property type="entry name" value="FAD_binding_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04954">
        <property type="entry name" value="SIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="SSF63380"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding FR-type" evidence="1">
        <location>
            <begin position="17"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="247" mass="27538" checksum="E06E8E58506375BD" modified="2018-07-18" version="1">MSIDLAASRVQRIRYEIKRRVLQVVRVESVSPHFKSVTFAGDALSDFISASFDDHVKFILSEEGAEEEMRRDYTPRYYNAAACELTLEFALHGDGPAADWAAQAEAGQRATIAGPRGSFIIPMDYDWHLLVGDETAVPAIARRLEELPATAHAIVVLQLADVSDRRKFQSAAKLDLHWVSNSAELMKIIRALKLPDGEGYAWCAGEASEMAALRRLLVEEKGHSRHAIRAAAYWKRGTVGHHENLEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2E5</accession>
    <name>A0A2S9H2E5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NMT1/THI5 like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1325</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94152">
        <property type="protein sequence ID" value="PRC94152"/>
        <property type="gene ID" value="S2091_1325"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015168">
        <property type="entry name" value="SsuA/THI5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09084">
        <property type="entry name" value="NMT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NMT1" evidence="1">
        <location>
            <begin position="46"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="338" mass="36207" checksum="E73A85E817BF17BE" modified="2018-07-18" version="1">MTKLPKLSTFLKSLFTLIMFAISTNSISAEKIILIVGGMEKQIYLPVKLAERLGYLKETGLDIELLSEPSGVNAVTEMLSGAAQGVVGFYDHTIDLQARGKQVQSVVQFSQAPGEAILVSKTASAHIKSPADFKGKTLGVTGLGSSTNFLTQFLASKYGVKNSEYTTLPVGSGSTFIAAMTQKKIDAGMTTEPTISRLTSTGAASILVDLRTLKATEAALGGAYPGACLYMPTAWVNSHKEQVQKIVTAFVKTLAYIQTHSAQEIADMMPPDYYKANKQQYIDSLSASKDMFTADGIMPESGPATVLNVLNGFNKAVQGKNINLSNTYTTEFVKAARK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2K8</accession>
    <name>A0A2S9H2K8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0832</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94211">
        <property type="protein sequence ID" value="PRC94211"/>
        <property type="gene ID" value="S2091_0832"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007396">
        <property type="entry name" value="TR_PAI2-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35802">
        <property type="entry name" value="PTHR35802"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04299">
        <property type="entry name" value="FMN_bind_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF010372">
        <property type="entry name" value="PaiB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="179" mass="20186" checksum="1912A3595B7D5CC5" modified="2018-07-18" version="1">MIVNHIPFLVDATRGEYGTLIGHVARANSIWKSFSSEIASVIIFQGPQGYITPSWYPSKHRHGKAVPTWNYTVVHAHGIPRAIEDKDWLLQHVTTLSDLYESKRAMPWRVSDAPSEYIDSMLNTIIGIEIPINAVVGQWKMSQNKPLSDKLGIIEGLHEHVDENSQQMVALVKRGNHKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2V8</accession>
    <name>A0A2S9H2V8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Growth regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0940</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94319">
        <property type="protein sequence ID" value="PRC94319"/>
        <property type="gene ID" value="S2091_0940"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007159">
        <property type="entry name" value="SpoVT-AbrB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037914">
        <property type="entry name" value="SpoVT-AbrB_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04014">
        <property type="entry name" value="MazE_antitoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00966">
        <property type="entry name" value="SpoVT_AbrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89447">
        <property type="entry name" value="SSF89447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SpoVT-AbrB" evidence="1">
        <location>
            <begin position="10"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="84" mass="9027" checksum="428FB5E2E97D5AC2" modified="2018-07-18" version="1">MGKTATLTVQQWGNSLAVRIPAALARKVNFVVGQPVEISTDDFGVVVHRKGSPKLTLEQRLAAFDPEKHGGEVIISSRVGAEVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2Z1</accession>
    <name>A0A2S9H2Z1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0924</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94303">
        <property type="protein sequence ID" value="PRC94303"/>
        <property type="gene ID" value="S2091_0924"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015667646" evidence="1">
        <location>
            <begin position="21"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="149" mass="16208" checksum="69078932BB23F45C" modified="2018-07-18" version="1">MKSYLMIAVLTMGTMSSVWAADSILELSLQDVLTMPEARDVLDGSVKFYLKGQVTPETVVMLKSAAVGNVKGNATEMGDRYACKQAALAALVSFHNRAKEKGANAVVDMVNYYKQVESARNTVIQCHVDHPFASVMFRGLFAKVAKGQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H365</accession>
    <name>A0A2S9H365_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0927</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94306">
        <property type="protein sequence ID" value="PRC94306"/>
        <property type="gene ID" value="S2091_0927"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015714952" evidence="1">
        <location>
            <begin position="29"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="205" mass="22738" checksum="1EE18D6488BAFA94" modified="2018-07-18" version="1">MKKCLRIYALIYSLTCTLIACISQQAIAQQDSPASNAQQAVTVPDGQHDFDFEIGTWKTHLSRLLHPPTGSTTWVAYEGTTIVRRVWNGRANLVELDVDGSAGHIQGLSLRLYNPDSHQWSLNFASISSGTVDAPTVGEFKNGRGEFYDQETLNGRSILVRFVISDITQNSCHFEQAFSKDGGKSWEVNWIATDTRIKGEADKTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3A1</accession>
    <name>A0A2S9H3A1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Bacterial regulatory protein, tetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1085</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94464">
        <property type="protein sequence ID" value="PRC94464"/>
        <property type="gene ID" value="S2091_1085"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="7"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="30"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="191" mass="21118" checksum="033911AC04015FD5" modified="2018-07-18" version="1">MATSKPGEKKLHILQTLASMLENPKAEKITTAALAARIGVSEAALYRHFASKAQMFEGLIEFIESSVFGLINQITTQQENGMLQAQEIITMLLSFSARNPGMTKVMTGHALINEDERLQLRMNQFADRIELSLKQSLRLAAVAGQINEADVAVRANLILSVVLGRWQRFVKTSFKNDPLENSAAQISFLLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3F3</accession>
    <name>A0A2S9H3F3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Addiction module antitoxin, RelB/DinJ family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0517</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RelB/DinJ antitoxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94514">
        <property type="protein sequence ID" value="PRC94514"/>
        <property type="gene ID" value="S2091_0517"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000987">
        <property type="term" value="F:cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015643">
        <property type="term" value="F:toxic substance binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044010">
        <property type="term" value="P:single-species biofilm formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1220.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013321">
        <property type="entry name" value="Arc_rbn_hlx_hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026262">
        <property type="entry name" value="DinJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007337">
        <property type="entry name" value="RelB/DinJ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38781">
        <property type="entry name" value="PTHR38781"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04221">
        <property type="entry name" value="RelB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003108">
        <property type="entry name" value="DinJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02384">
        <property type="entry name" value="RelB_DinJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="93" mass="10318" checksum="9A1B9B6D9696CDBA" modified="2018-07-18" version="1">MATTTSMLHVRVDDETKVQATEALALMGLSMSDAVRLFLHRVIVDQAFPLELKVPNAETRAAMAESRSMMASRRSRFTSADALFNDLEKNSSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3T9</accession>
    <name>A0A2S9H3T9_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptidoglycan glycosyltransferase</fullName>
            <ecNumber evidence="4">2.4.1.129</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">S2091_0640</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>[GlcNAc-(1-&gt;4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n)-di-trans,octa-cis-undecaprenyl diphosphate + beta-D-GlcNAc-(1-&gt;4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate = [GlcNAc-(1-&gt;4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n+1)-di-trans-octa-cis-undecaprenyl diphosphate + di-trans,octa-cis-undecaprenyl diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23708"/>
            <dbReference type="Rhea" id="RHEA-COMP:9602"/>
            <dbReference type="Rhea" id="RHEA-COMP:9603"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58405"/>
            <dbReference type="ChEBI" id="CHEBI:60033"/>
            <dbReference type="ChEBI" id="CHEBI:78435"/>
            <dbReference type="EC" id="2.4.1.129"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">In the C-terminal section; belongs to the transpeptidase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">In the N-terminal section; belongs to the glycosyltransferase 51 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.129" evidence="4"/>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94637">
        <property type="protein sequence ID" value="PRC94637"/>
        <property type="gene ID" value="S2091_0640"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004180">
        <property type="term" value="F:carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008658">
        <property type="term" value="F:penicillin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008955">
        <property type="term" value="F:peptidoglycan glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3810.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001264">
        <property type="entry name" value="Glyco_trans_51"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023346">
        <property type="entry name" value="Lysozyme-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011815">
        <property type="entry name" value="PBP_1c"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009647">
        <property type="entry name" value="PBP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036950">
        <property type="entry name" value="PBP_transglycosylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001460">
        <property type="entry name" value="PCN-bd_Tpept"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06832">
        <property type="entry name" value="BiPBP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00912">
        <property type="entry name" value="Transgly"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00905">
        <property type="entry name" value="Transpeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53955">
        <property type="entry name" value="SSF53955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02073">
        <property type="entry name" value="PBP_1c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="10" id="KW-0133">Cell shape</keyword>
    <keyword evidence="14" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="7" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="11" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="6" id="KW-0645">Protease</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Transgly" evidence="17">
        <location>
            <begin position="58"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="domain" description="Transpeptidase" evidence="16">
        <location>
            <begin position="307"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="domain" description="BiPBP_C" evidence="18">
        <location>
            <begin position="703"/>
            <end position="780"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF00905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF00912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF06832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="PRC94637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="787" mass="86796" checksum="E2A66523A19DED3B" modified="2018-07-18" version="1">MFHRQFATSLKHHIRSHKIGYGCLSALLVLLWSADKLFPLPAPGRDSFNVIVVAKDGTPLRAFPDRAHIWRHPIKLDAVSPYYIQSLIAYEDKNFWWHPGVNPLSLLRATYQWLRYGHIVSGGSTLTMQVARILDPTPRTMSGKLKQIARALQLEYHYSKTEILDLYMNFAPMGGVLEGVEAASRAYLGKPANRLTHAEAALLTVLPQLPSVLRPDRYPQKAQLARNKVVYRMRGIWSTAEIKDALTEPIAALTVREPLLAPLLAQRMKSQNPGQLRIDTTIDSIAQQTVETLLVDRVNVLPPRISMAAMVMDNRTAEVVAYAGSADFTDRERFSNVDMVRASRSPGSTLKPFLYAFALDEGLIHSESLLSDTPQSFSGYQPGNFQQNFHGPVSVSEALVKSLNVPAVQVLDQLGSVPFVAMLRRGGLKLEFPKGAAPNLSVILGGAGARLEDMVAAYSSLARAGMAVTPRFVPSAPLQERRMMSEGAAFIVRDILETGGPVGRAVEGNGSYRGIAWKTGTSFGFRDAWALGVSQRYTIGVWVGRPDGTPNPGFFGANIAAPLLVDIFNALPDGRNLSPNPAPATVKQEKICWPSGTRASDNIIDGNEDLCPLQRTAWTLNGIAPPTFPDRLQAMSPRLTYFVDQQTGKRVLPDCAQHAYRQQQIMRWPAALQLWLDPDLHKKSLPPEWDSSCSAHYSSSYSDGNALKIMGLNDGELIRQANGGKLPEAKLELRGSHGEVNWMVNGRLLTDKRINQTIKFPNAGRYDITAFDMQGNFDRIGVSVQMQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3V0</accession>
    <name>A0A2S9H3V0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Putative metalloendopeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">S2091_0549</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94546">
        <property type="protein sequence ID" value="PRC94546"/>
        <property type="gene ID" value="S2091_0549"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08662">
        <property type="entry name" value="M13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1380.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000718">
        <property type="entry name" value="Peptidase_M13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018497">
        <property type="entry name" value="Peptidase_M13_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042089">
        <property type="entry name" value="Peptidase_M13_dom_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008753">
        <property type="entry name" value="Peptidase_M13_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11733">
        <property type="entry name" value="PTHR11733"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01431">
        <property type="entry name" value="Peptidase_M13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05649">
        <property type="entry name" value="Peptidase_M13_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00786">
        <property type="entry name" value="NEPRILYSIN"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51885">
        <property type="entry name" value="NEPRILYSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015550116" evidence="8">
        <location>
            <begin position="34"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M13_N" evidence="10">
        <location>
            <begin position="58"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M13" evidence="9">
        <location>
            <begin position="494"/>
            <end position="692"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF05649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC94546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="695" mass="76458" checksum="62F9A33C7B40C5BF" modified="2018-07-18" version="1">MKNTKTNLRLKPIALFCMQLMLALPATTLVAHANETTPASAPVAVSALQSGMDKTVAPGDDFYRYVNGGWEKTAVIPNDKSAVGVTSTLKDESDAIVLKLIEQAAQAPADSPARKVGDYYAAYLNTDAINQRGLQAIAPQLHSIASISNKSALATYLGKHLRADVDPLNATSFFTENLFGLWVAQGFHDHTKYTGYLLQGGLGLPDREYYLSASPKMANIRTEYQAHIAALFKLANIAEPEQAAKRVFDLEMRIAQGHAKRSDSSDMDKADNSWSRAAFAKQAPGLDWNAYFSAAGLAAQPSFIVWHPTAFKSSAALVASTPLETWKDYLRFHALNQHTSVLPQAFFDQKFKFSSSLTGAKAPLPRWKYAVNATNSALGEEVGKLYVAQNFSPEAKAKINTMVSVLLTAFKERVSNISWMSASTKQEALAKINSFYVGVGYPDKWRDYSALTVDAKDAFGNGERAQEFAYKNALAKFGKPVDVTEWCMTPQTVNAVNMPMQNAINFPAAYLQFPNFDINASDAVNYGAIGSTIGHEISHSFDHTGAMIDAKGELRNWWTKDDLSHFQTSAKALADQFSSYKPFPDLAVNGEQTLDENIADLTGLMAAFDAYHAAMKQKGQTATKETDQEFFLANAYKYRGKMRDEVLRSAIIGDGHAPGHYRALTVRNLDAWYDGFNIQPGQQLYLAPNERVKIW</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3Y3</accession>
    <name>A0A2S9H3Y3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative integral membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0692</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94689">
        <property type="protein sequence ID" value="PRC94689"/>
        <property type="gene ID" value="S2091_0692"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008535">
        <property type="entry name" value="DUF817"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05675">
        <property type="entry name" value="DUF817"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF009141">
        <property type="entry name" value="UCP009141"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="29"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="64"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="124"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="158"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="185"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="211"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="253"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="281" mass="32272" checksum="71B8DAA1322E93A1" modified="2018-07-18" version="1">MPIQALDNHLLNLRAKPDLSGLSRFVVEFLYFGIKEARSCLFAGLFFAAIFCLPRSGIMGIPRYDALLIIAVLIQLWMVWTKLETTDELKAICLFHVIGFALEVFKTSSGIKSWSYPDLAYSKLLGVPLFSGFMYAAVGSYIIQAWRMLDVKIRHYPPYWMATVIAILIYANFFTHHYIGDYRWYIAACTLGLYARSTVVFTPLDRERRMPLLLAFVLIGFFIWLAENISTFFGIWRYPDQIGAWATVNVGKWSSWSLLVIMTFTIVGNLKHIKQRIHIPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H445</accession>
    <name>A0A2S9H445_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0750</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94747">
        <property type="protein sequence ID" value="PRC94747"/>
        <property type="gene ID" value="S2091_0750"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015417315" evidence="1">
        <location>
            <begin position="27"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="239" mass="25723" checksum="89C52A91B30514DF" modified="2018-07-18" version="1">MKKLTNTLTGFAALLPLLIFSNTTNAADAPREPLAVLNSLNDRIYVLGETGGNPTAMIDAEAKAADEIRQYIATGATAGLLADGKDEDSPLVSAAYLGYPNVVTALLTSSIIKKHINDADRSGLTPWIAANFSIQQTMWVCNPEIFDIPTKFVPMVVSQPYYASNPTPPYKEVRNVLEKSGASPDLAKAKLLWITHCTRLASEAKAKVQASADLQKTLQELGAADFLTKLSTIEKESGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H471</accession>
    <name>A0A2S9H471_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Tfp pilus assembly protein PilP</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0785</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94782">
        <property type="protein sequence ID" value="PRC94782"/>
        <property type="gene ID" value="S2091_0785"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007446">
        <property type="entry name" value="PilP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04351">
        <property type="entry name" value="PilP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016481">
        <property type="entry name" value="Pilus_assembly_PilP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="176" mass="19688" checksum="5E3E9DAE7AC5636C" modified="2018-07-18" version="1">MKKLLCVMLLPLGLAACGESGEQEVQQWMDKTKLETKPSIAKLKEPKEFIPFVYDKKDEIDPFNPVKLQSALAKLNPGNGHGIKPDLDRRREALESMPLDTLKMVGTLTQGANHYALLLVDSKSIYQVKAGNYVGQNFGLVTKVNDDSIEIKEIYLDSGGDWAERVQKLELQEAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H479</accession>
    <name>A0A2S9H479_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">3-deoxy-D-manno-octulosonate 8-phosphate phosphatase KdsC</fullName>
            <ecNumber evidence="5">3.1.3.45</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">KDO 8-P phosphatase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_0798</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>3-deoxy-alpha-D-manno-2-octulosonate-8-phosphate + H2O = 3-deoxy-alpha-D-manno-oct-2-ulosonate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:11500"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:85985"/>
            <dbReference type="ChEBI" id="CHEBI:85986"/>
            <dbReference type="EC" id="3.1.3.45"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the KdsC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.45" evidence="5"/>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94795">
        <property type="protein sequence ID" value="PRC94795"/>
        <property type="gene ID" value="S2091_0798"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019143">
        <property type="term" value="F:3-deoxy-manno-octulosonate-8-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010023">
        <property type="entry name" value="KdsC_fam"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006118">
        <property type="entry name" value="KDO8-P_Ptase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01138">
        <property type="entry name" value="C1.6.2:_Deoxy-d-mannose-octulo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01670">
        <property type="entry name" value="KdsC-phosphatas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="8">
        <location>
            <position position="21"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="23"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="114"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00020092"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00031051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR006118-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC94795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="178" mass="19262" checksum="5689DFFE742F56E8" modified="2018-07-18" version="1">MTQNQISAQQKAAQVRIMIFDVDGVLTDGSMQYSAEGELIKRFFVHDGLGIQLLQKMGITTAIISARQTPIVNKRAADLGITYVYQGNHDKRITFAQLLNDTGVAAHECGFMGDDIVDLPLFAKVGFAVSVPNAHPEASSRADYITKAAGGLGAVREICDFILRAQNKYDAALAPYLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4J1</accession>
    <name>A0A2S9H4J1_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">K(+)-insensitive pyrophosphate-energized proton pump</fullName>
            <ecNumber evidence="9">7.1.3.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Membrane-bound proton-translocating pyrophosphatase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Pyrophosphate-energized inorganic pyrophosphatase</fullName>
            <shortName evidence="9">H(+)-PPase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">hppA</name>
        <name evidence="10" type="ORF">S2091_0099</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>diphosphate + H(+)(in) + H2O = 2 H(+)(out) + 2 phosphate</text>
            <dbReference type="Rhea" id="RHEA:13973"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="EC" id="7.1.3.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.1.3.1" evidence="9"/>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94904">
        <property type="protein sequence ID" value="PRC94904"/>
        <property type="gene ID" value="S2091_0099"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004427">
        <property type="term" value="F:inorganic diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009678">
        <property type="term" value="F:pyrophosphate hydrolysis-driven proton transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01129">
        <property type="entry name" value="PPase_energized_pump"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004131">
        <property type="entry name" value="PPase-energised_H-pump"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31998">
        <property type="entry name" value="PTHR31998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03030">
        <property type="entry name" value="H_PPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001265">
        <property type="entry name" value="H+-PPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01104">
        <property type="entry name" value="V_PPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="7 9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="4 9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-1278">Translocase</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="57"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="81"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="122"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="164"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="237"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="262"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="296"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="324"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="382"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="405"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="465"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="502"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="569"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="594"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="site" description="Determinant of potassium independence" evidence="9">
        <location>
            <position position="460"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC94904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="725" mass="74334" checksum="B717D5E732E0AC51" modified="2018-07-18" version="1">MVTSLWFVIGCGLIAVLYGLISRSWILKQDAGNARMQEIAAAIQQGAAAYLARQYRTIAIVGVILFAIIFAVPGLGMPTAIGFLIGAVLSGACGFIGMNVSVRANVRTAQAATLGINPALDVAFKGGAITGMLVVGLGLLGVSLFYWALIAYAPAGTIHSQHDLLKPMIGLAFGASLISIFARLGGGIFTKGADVGADLVGKVEAGIPEDDPRNPAVIADNVGDNVGDCAGMAADLFETYVVTLIATMLLGALLMPDMSAQAALYPMLLGAVSILASIVGCSMVKAKPGKKIMSALYTGLWWAAGLSLIGFTIVTKLVLPEAQFMPMLGSTVVGIVLTGLMVYITEYYTGTDFYPVRHIAQASTTGHGTNIIAGLGVSMKSTAYPVLAVCVAILVAYHLAGLYGIAIAATSMLSMAGIIVALDAYGPITDNAGGIAEMSEMPESVRAVTDPLDAVGNTTKAVTKGYAIGSAGLAALVLFADYTHALESVGKSVTFDLSNPNVIVGLFIGGLIPYLFGALAMEAVGRAAGAVVVEVRRQFKEIKGIMDGTGKPEYDKAVDMLTSSAIKEMIIPSLLPVVVPVLVGLLLGPAALGGLLMGTIVTGLFVAISMTTGGGAWDNAKKYIEDGNHGGKGSEAHKAAVTGDTVGDPYKDTAGPAINPLIKIINIVALLLVPLLPMPAQEPVPVQFVPAAVNSSEMKVLPAGVVDAASATPVSTDTSKPAPVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4J7</accession>
    <name>A0A2S9H4J7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cold shock protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_0083</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94888">
        <property type="protein sequence ID" value="PRC94888"/>
        <property type="gene ID" value="S2091_0083"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04458">
        <property type="entry name" value="CSP_CDS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012156">
        <property type="entry name" value="Cold_shock_CspA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011129">
        <property type="entry name" value="CSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019844">
        <property type="entry name" value="CSD_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002059">
        <property type="entry name" value="CSP_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00313">
        <property type="entry name" value="CSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002599">
        <property type="entry name" value="Cold_shock_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00050">
        <property type="entry name" value="COLDSHOCK"/>
    </dbReference>
    <dbReference type="SMART" id="SM00357">
        <property type="entry name" value="CSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00352">
        <property type="entry name" value="CSD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51857">
        <property type="entry name" value="CSD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CSD" evidence="3">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC94888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="68" mass="7394" checksum="A3D9193C71F7F8D2" modified="2018-07-18" version="1">MATGTVKWFNDSKGFGFITPDDGGEDLFAHFSAIQMNGFKTLKEGQKVQFEVTQGPKGKQASNIQAPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4M5</accession>
    <name>A0A2S9H4M5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0021</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94826">
        <property type="protein sequence ID" value="PRC94826"/>
        <property type="gene ID" value="S2091_0021"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="277" mass="31252" checksum="4C558F1F177B7B24" modified="2018-07-18" version="1">MRFNAISQYFDVYLVRHLGEIFCCKASLPTCFPFNFTKIEKHMQIFNLKLIFFTAVLAVTMNSSYAQSVNAPVYAVGEKWEFMKKDLWTGKVIQRYTVKNIGIAGDYLRRSFETTNISANGDITKPQFTESTVRADMNENIMFHGEKSIKVWYKWPLEIGKKWSLQSKSEIAPTAANAVAQTMVSTWNAEVVQWENVDMPSGKVKALKIVYKLAWTLDSPTGGGDGVYTVWYSPEQKNVVQSIYETFTADGSPQLRTITQLVLTDGIVKTSTPAASN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4M7</accession>
    <name>A0A2S9H4M7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ABC-type branched-chain amino acid transport systems ATPase component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_0135</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94940">
        <property type="protein sequence ID" value="PRC94940"/>
        <property type="gene ID" value="S2091_0135"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-1278">Translocase</keyword>
    <feature type="domain" description="ABC transporter" evidence="7">
        <location>
            <begin position="2"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="34"/>
            <end position="41"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC94940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="243" mass="25836" checksum="993543F8D91E7FE6" modified="2018-07-18" version="1">MLTISNLYAGYGKVEVLHGISLDIPKGRLVTLIGSNGAGKTTTMRAISGMLKPSSGSVRLNDQDITGFDAHRIARAGLAHSPEGRRVFASMTVTDNLLLGAFPRYVGARPKGDIKLDLEKALELFPRLKERRSQLAGTLSGGEQQMLAMARAVMLNPDVILLDEPSMGLAPILVEEVFRIITRLKSEGVTMLLVEQFAAAALNVADYGYVLENGSISVHGPAASLKTDPKVVAAYLGGAAAHN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4Q8</accession>
    <name>A0A2S9H4Q8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cation/multidrug efflux pump</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0142</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94947">
        <property type="protein sequence ID" value="PRC94947"/>
        <property type="gene ID" value="S2091_0142"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2090.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027463">
        <property type="entry name" value="AcrB_DN_DC_subdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001036">
        <property type="entry name" value="Acrflvin-R"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32063">
        <property type="entry name" value="PTHR32063"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00873">
        <property type="entry name" value="ACR_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00702">
        <property type="entry name" value="ACRIFLAVINRP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82714">
        <property type="entry name" value="SSF82714"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="333"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="359"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="389"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="430"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="462"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="534"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="851"/>
            <end position="870"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="877"/>
            <end position="897"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="903"/>
            <end position="927"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="948"/>
            <end position="968"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="980"/>
            <end position="1003"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1024"/>
            <end position="1048"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="1066" mass="115765" checksum="50621591504D0EAD" modified="2018-07-18" version="1">MFLSDFSIKRPIATIVIIIMLMCMGLLALKKLRVNQNPDVQFPLIVVSVPYPGASPDTVEHEVINRIEKSLQSITGVDQMRSTANEGSATFLIFFKFGKNMVEAGDEIRNAIGSIRYKLPAEIREPVLERIDPAADPIMEIALSSTVQSHAEISRLAEDQLAEKFRAIDGVAVVTVNGALRRELSVLLKAEKLREYNVSVNEVVNALRNQNTNAPVGKVRGTLSEQSIRLVGRIETPAEFEQIVVKHNGDQVVRLAQVASIEDGFAEVNSYSVRNARPNVNISVVRANSSSTITVANKVRDLVAEINKTLPNGTDLVVTNDGGENAQSSLDNVIDSLMFGAVLTIFVVYIFLNSWRSTLITALSLPTSVIAAFIAVWACGFTLNFMTLLGLSLAIGVLIDDAIVVRENIVRHMEMGKDRRTAASEGTREIGMAVASTTFSIISVFIPVAFMQGEAGEWFRPFALTVAISVLVSLFISFTLDPMLSAYWGDPVGQHLKPKRGISLWLSKFNHWFDHQANRYGSVIAWALHHRRSMAVIAGASLVGAIALQATLGGTDFLPATDAGQIAIDVRTPSSSSIEYNRLKIEKAAELARTISETVATNSNVNAAGGRIYVDIGKSTKRKRSASQIAVELRGLMKRLVGAEYVVQDDLNNGGNKPVQIKFFGTDSRRLTTITNDFMEKLRHVPGAVDVGLSEQAPKDELQIELNRGLANSLGISVADAAQSLRVAFAGVEVGDWVDPTGESRDVAVRLQADDRLNAENIEHLPIAVNGGNSMVPLDQIATIKMGKGPSKIEHSDGKRMINVSANAEGRSAGEVTSDALTIAKAIDFPPGFGIELGGAARSQQELFSEMFIALIMGIGLMYLILVIQFGSFTAPLAVMLSLPLSLIGVVIALLLTKGTINLMSFIGVIMLMGLVAKNAILLLDCARKHEALGHDREESLMYAGRMRLRPILMTTFALIAGMMPVAIGMGEGGEFYRPLAVAIIGGTITSTMLTLLVVPTFYDSIEIARDRMFAKMAARTERMNVVVAFFLTMFEAFLTLIFVRWIFRQVIKLSGLLGGRKSMAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4U6</accession>
    <name>A0A2S9H4U6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0205</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95010">
        <property type="protein sequence ID" value="PRC95010"/>
        <property type="gene ID" value="S2091_0205"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="182"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="212"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="237"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="70"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="124"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC95010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="353" mass="40206" checksum="C0504CE775254196" modified="2018-07-18" version="1">MSKSLRLSEKWFRFGLWIVAVVFAGFLIGLGSNVVQNLPQVEHHYSMSDFIDKNAAAQADLAIKTSRDQRKINDDNLDQAERQYESAKADSQTARDSFTSWIATRRATALASQDSDLIARNQQLDKLKNTERSTLAQVQQLQEKNRSIMQEQQNAETQLSQLQKTADVALEAEQRKQDLRVFLYRLALTLPLLVVAGWLLKKKRKSTYWPFVWGFVFFSVFTFFVELVPYLPSYGGYVRYGVGIIITVLVGRQAIISLNAYLERQKLAEQLPNQQRREELSYDVALTRLAKQVCPGCEREVDLKNPANDFCQHCGICLFDHCRSCNTRKNAFTKFCHSCGANAANKGLETTVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4W5</accession>
    <name>A0A2S9H4W5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Membrane protease subunits stomatin/prohibitin-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_0176</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the band 7/mec-2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94981">
        <property type="protein sequence ID" value="PRC94981"/>
        <property type="gene ID" value="S2091_0176"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043202">
        <property type="entry name" value="Band-7_stomatin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001107">
        <property type="entry name" value="Band_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036013">
        <property type="entry name" value="Band_7/SPFH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001972">
        <property type="entry name" value="Stomatin_HflK_HflKC_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10264">
        <property type="entry name" value="PTHR10264"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01145">
        <property type="entry name" value="Band_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00721">
        <property type="entry name" value="STOMATIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00244">
        <property type="entry name" value="PHB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117892">
        <property type="entry name" value="SSF117892"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="domain" description="PHB" evidence="3">
        <location>
            <begin position="22"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC94981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="254" mass="28758" checksum="413FA99EDF0C3C0A" modified="2018-07-18" version="1">MFSELNLILLFTAFAVTIFLVSAIWIFREYERGVVFTLGRFWKVKGPGLVIIIPWVQQVVRVDLRTVVLEVPTQDVISRDNVSVKVSTVVYFRIVDPQKAIIQVVNYLNATSQLAQTMLRSVLGKHSLDDMLAEREKLNHDIRESLDAQTDSWGIKVENVEIKQVDLTESMIRAIARQAEAERERRAKVIHAEGELQASEKLYAAAKILAQEPQAIQLRYLETLTVIGADKNTTIVFPLPMELATFLGQLKPKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H518</accession>
    <name>A0A2S9H518_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Protein MgtC</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_0277</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell inner membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the MgtC/SapB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95082">
        <property type="protein sequence ID" value="PRC95082"/>
        <property type="gene ID" value="S2091_0277"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003416">
        <property type="entry name" value="MgtC/SapB/SrpB/YhiD_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33778">
        <property type="entry name" value="PTHR33778"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02308">
        <property type="entry name" value="MgtC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01837">
        <property type="entry name" value="MGTCSAPBPROT"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="35"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="62"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="87"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="112"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC95082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="234" mass="25153" checksum="B2D9DA24B3ED28C2" modified="2018-07-18" version="1">MVWYEFTLRVLLALFLGSLIGTERQLRQRMAGLRTNALVAAGATLFVSTAGLSSFPAEGMRIAAQVVSGIGFLGAGVIMREGLNVRGLNTAATLWCSAAIGVLSGLGHEVEAAIGTFFILIANFILRDVAQRMNRRSAAAGLEVEQVYRINIVCDSAEEVHVRNLLLHTIQGMSPLVLQSLHSEDVINGGKIEVRADVLAVPGHHNLLEQIVSRVSMEKSVSVVRWAVLNGALE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5F2</accession>
    <name>A0A2S9H5F2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Alkyl sulfatase and related hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_0358</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the metallo-beta-lactamase superfamily. Type III sulfatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95163">
        <property type="protein sequence ID" value="PRC95163"/>
        <property type="gene ID" value="S2091_0358"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018741">
        <property type="term" value="F:alkyl sulfatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018909">
        <property type="term" value="P:dodecyl sulfate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07710">
        <property type="entry name" value="arylsulfatase_Sdsa1-like_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038536">
        <property type="entry name" value="Alkyl/aryl-sulf_dimr_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029229">
        <property type="entry name" value="Alkyl_sulf_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029228">
        <property type="entry name" value="Alkyl_sulf_dimr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044097">
        <property type="entry name" value="Bds1/SdsA1_MBL-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036527">
        <property type="entry name" value="SCP2_sterol-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14864">
        <property type="entry name" value="Alkyl_sulf_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14863">
        <property type="entry name" value="Alkyl_sulf_dimr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55718">
        <property type="entry name" value="SSF55718"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Lactamase_B" evidence="5">
        <location>
            <begin position="132"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00033751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC95163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="660" mass="72158" checksum="240AAC1F9C075236" modified="2018-07-18" version="1">MKSISVSVSIAAIVVAGAVATSMYFTKHTERLVSTADATVSTVQYNAGFAKDLKLDDPVDFEAASRGLIARPTGKILSANGTVLHDFDAYKFIDGPAPSTVNPSLWRHARLNAEMGLFKVTDGIYQVRGFDIANMTIIEGKSGWIIVDTLTARESAAAALAFARQKLGDKPVSAIIFSHSHIDHFGGVLGVISADEVRQRNIPVIAPKGFMEEATSENVLVGTAMGRRSAYQFGRNLPPNAKGLVDTGLGKDVVYGTFGIMQPTKLISQSSEELTVDGVRFVFHNVPGAEAPAELTFSIPEYKAYCGAELVNQTMHNLLPIRGAKVRDALGWSDYMDQAIDQVSGIEVMFSQHTWPVWGNAQIVNMLKLHRDTYKYMHDQTVRLINSGYTPLEIADMIKLPQSLASQFGVRGYYGDLRHNVKAIYQFYLGAYDGNPAELNPLAPAESSKHYLELMGGADKVLAAAKSAYDKGEYRWTAELLNHAVLADPGNKSVSELLAKTYEQMGYQAESATWRNSYLTAAGELRNGPPKKGVNRADFVELLMQTPTERFLEAMAAALNGPDAEGKNYKLNLVLTDAKESYVLWIENAVLHYRKAPTANDANATLTLTKPLFVKMMVGTLGIKDVIMSDDLKVDGSKIELIRFLALIEKQPGTFGIVIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5H8</accession>
    <name>A0A2S9H5H8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator PadR-like family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0321</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95126">
        <property type="protein sequence ID" value="PRC95126"/>
        <property type="gene ID" value="S2091_0321"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005149">
        <property type="entry name" value="Tscrpt_reg_PadR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03551">
        <property type="entry name" value="PadR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PadR" evidence="2">
        <location>
            <begin position="70"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC95126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="223" mass="24593" checksum="AF776D13A237746A" modified="2018-07-18" version="1">MRHHHEQHGHHFSHHGHDRHSDHLAQHAMGRHEGGRGGRNGFGGDFGGEGGGDGFNRSRKFSSQDLQLLLLALLADKPAHGYELIKALEARSNGFYTPSPGMVYPALTYMEELGHVTVTLDGNRKCYALADEGKEYLAANQERVDMMLARITHIARKMDSIRRAYSGEAGAEVADENNGWLPELVEARRALKSALLQRSDAPATEQRRIAAVLVQAAREISGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5K8</accession>
    <name>A0A2S9H5K8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Tol-pal system-associated acyl-CoA thioesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0474</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95279">
        <property type="protein sequence ID" value="PRC95279"/>
        <property type="gene ID" value="S2091_0474"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016790">
        <property type="term" value="F:thiolester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006683">
        <property type="entry name" value="Thioestr_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014166">
        <property type="entry name" value="Tol-Pal_acyl-CoA_thioesterase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006684">
        <property type="entry name" value="YbgC/YbaW"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03061">
        <property type="entry name" value="4HBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02799">
        <property type="entry name" value="thio_ybgC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00051">
        <property type="entry name" value="TIGR00051"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4HBT" evidence="2">
        <location>
            <begin position="51"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC95279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="172" mass="19779" checksum="92933B48E62311B1" modified="2018-07-18" version="1">MPEYAKKHKCIFDVKKYAKMPDFSGYEKAQVIQDSNFCWPLRIYYEDTDAGGIVYYANYLKYFERARTEWLRQLGVNQQELADQQQAMFVVKSSLVDYHLPARLDDELQLITVVEKLGRASLVFVQEAWRGTQCLVSGRFKVGCVDTQTIRPCAIPPAVLQALQASHFPSLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5L8</accession>
    <name>A0A2S9H5L8_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Dihydroorotate dehydrogenase (quinone)</fullName>
            <ecNumber evidence="11">1.3.5.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">DHOdehase</fullName>
            <shortName evidence="11">DHOD</shortName>
            <shortName evidence="11">DHODase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Dihydroorotate oxidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">pyrD</name>
        <name evidence="13" type="ORF">S2091_0484</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 11">Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>(S)-dihydroorotate + a quinone = a quinol + orotate</text>
            <dbReference type="Rhea" id="RHEA:30187"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:30839"/>
            <dbReference type="ChEBI" id="CHEBI:30864"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="EC" id="1.3.5.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
        <text evidence="11">Binds 1 FMN per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4 11">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; orotate from (S)-dihydroorotate (quinone route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 11">Cell membrane</location>
            <topology evidence="3 11">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 11">Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.5.2" evidence="11"/>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95289">
        <property type="protein sequence ID" value="PRC95289"/>
        <property type="gene ID" value="S2091_0484"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00070">
        <property type="reaction ID" value="UER00946"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004152">
        <property type="term" value="F:dihydroorotate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006207">
        <property type="term" value="P:'de novo' pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044205">
        <property type="term" value="P:'de novo' UMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd04738">
        <property type="entry name" value="DHOD_2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00225">
        <property type="entry name" value="DHO_dh_type2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005720">
        <property type="entry name" value="Dihydroorotate_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012135">
        <property type="entry name" value="Dihydroorotate_DH_1_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005719">
        <property type="entry name" value="Dihydroorotate_DH_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001295">
        <property type="entry name" value="Dihydroorotate_DH_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01180">
        <property type="entry name" value="DHO_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000164">
        <property type="entry name" value="DHO_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01036">
        <property type="entry name" value="pyrD_sub2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00911">
        <property type="entry name" value="DHODEHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00912">
        <property type="entry name" value="DHODEHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 11" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7 11" id="KW-0288">FMN</keyword>
    <keyword evidence="10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="9 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8 11" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DHO_dh" evidence="12">
        <location>
            <begin position="51"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="11">
        <location>
            <begin position="114"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="11">
        <location>
            <begin position="253"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="11">
        <location>
            <position position="182"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="65"/>
            <end position="69"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="69"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="89"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="146"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="179"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="184"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="224"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="252"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="275"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="304"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="325"/>
            <end position="326"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00005359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PRC95289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="345" mass="36766" checksum="22ECA1E61E04F10C" modified="2018-07-18" version="1">MSTKLLYAFARPFLFSMDAESAHHLTLPLLKNAVALGMGNLITRPSSDPRTVMGITFPNPIGLAAGLDKDGAYIDALAALGFGSIEIGTVTPRAQAGNPKPRMFRLPQAQAIINRMGFNNGGVDAFISNVQDSRFYQDKLGVLGLNIGKNADTPIERAADDYLHCLEKVYPYASYVTVNISSPNTKNLRQLQGANELDDLLAKLKDAQQRLSDKHKRYVPLALKIAPDMDAEQIKMIADNLLQHKIDAVIATNTTLSRDAVAGLNHAAEAGGLSGAPVFELSNAVIRGLKAELGDAIPIIGVGGILSGSDAKAKIAAGAELVQIYSGLIYQGPALIRECAEAIKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5X7</accession>
    <name>A0A2S9H5X7_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Serine hydroxymethyltransferase</fullName>
            <shortName evidence="7">SHMT</shortName>
            <shortName evidence="7">Serine methylase</shortName>
            <ecNumber evidence="7">2.1.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">glyA</name>
        <name evidence="10" type="ORF">S2091_0481</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + glycine + H2O = (6S)-5,6,7,8-tetrahydrofolate + L-serine</text>
            <dbReference type="Rhea" id="RHEA:15481"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="EC" id="2.1.2.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 7 8">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Amino-acid biosynthesis; glycine biosynthesis; glycine from L-serine: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="7">One-carbon metabolism; tetrahydrofolate interconversion.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the SHMT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.1" evidence="7"/>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95286">
        <property type="protein sequence ID" value="PRC95286"/>
        <property type="gene ID" value="S2091_0481"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00193"/>
    <dbReference type="UniPathway" id="UPA00288">
        <property type="reaction ID" value="UER01023"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004372">
        <property type="term" value="F:glycine hydroxymethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019264">
        <property type="term" value="P:glycine biosynthetic process from serine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035999">
        <property type="term" value="P:tetrahydrofolate interconversion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00378">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00051">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001085">
        <property type="entry name" value="Ser_HO-MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019798">
        <property type="entry name" value="Ser_HO-MeTrfase_PLP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039429">
        <property type="entry name" value="SHMT-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11680">
        <property type="entry name" value="PTHR11680"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00464">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000412">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00096">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4 7" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="6 7 8" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SHMT" evidence="9">
        <location>
            <begin position="8"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="125"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="35"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="55"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="57"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="64"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="65"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="99"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="121"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="175"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="203"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="228"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="235"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="360"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="7 8">
        <location>
            <position position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000412-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC95286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="415" mass="45170" checksum="437C82DDFBE00F29" modified="2018-07-18" version="1">MFTKNHTLDQIDPEIFAVIQLENQRQQEHIELIASENYTSPAVMEAQGSQLTNKYAEGYPGKRYYGGCEHVDVVEQLAIDRLKKLFGAEAANVQPNSGSQANQGVFFAVLKPGDTIMGMSLAEGGHLTHGMPLNMSGKWFNVVSYGLNDKEEIDYEAMERLARETKPKLIIAGASAYSLRIDFERFSKIAKEVGAYFMVDMAHYAGLIAAGVYPNPVPYADFVTSTTHKSLRGPRGGIILMKAEHEKIINSAIFPGLQGGPLMHVIAGKAVAFKEALTPEFKTYQEQVVKNANALANALIERGLRIISGRTESHVMLVDLRSKNITGKAAEAVLGSAHITCNKNSIPNDPEKPFVTSGIRLGSPAMTTRGFKEADAAKVGHLLADVLDNPTDAATIERVKAEVKKLTDAHPVYSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSC4</accession>
    <name>A0A2S9GSC4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4703</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000046">
        <property type="protein sequence ID" value="PRC90596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90596">
        <property type="protein sequence ID" value="PRC90596"/>
        <property type="gene ID" value="S2091_4703"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC90596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="200" mass="23160" checksum="CE33260058C89C9C" modified="2018-07-18" version="1">MKDYLYLWNDPDRQFLVASGIEFKDFLKSLDNLGGIALIEHQSEISEFDPNSRFEFVSSSNIPKLINENIYSWGNFVWADYADSTIPIISDKEIAELLFFAHKVVPLTTSKIASLNNKYLAYIHDDGWYLQLHYSNWEHIKNLIESLKITNIGAINLSDLKQGKYALWLQGGVIHHEEMTHDVDIVLNRRLFVNGKKIKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSH9</accession>
    <name>A0A2S9GSH9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4638</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000040">
        <property type="protein sequence ID" value="PRC90655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90655">
        <property type="protein sequence ID" value="PRC90655"/>
        <property type="gene ID" value="S2091_4638"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032874">
        <property type="entry name" value="DDE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13610">
        <property type="entry name" value="DDE_Tnp_IS240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_Tnp_IS240" evidence="1">
        <location>
            <begin position="38"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="200" mass="23684" checksum="61A212EED29B881A" modified="2018-07-18" version="1">MMAKRGVIVSYETIRNWSQKFGGIYAKRLRSRSKRSNDHWHLDEVYLSINGKAHYLWRAVDQDGEVLDILVQPRRNKRAAMKFFRKLLKNLQYIPRVIITDKLRSYAAAKAEIMPEVKHIQGKGANNRAENSHQPTRERERRMRGFKSAGHAQRFLASYSVIASFFRPSRHLLAAKNYREIMRRRFIEWSEVVNSDFTFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSK0</accession>
    <name>A0A2S9GSK0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Multidrug resistance efflux pump</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_4592</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000038">
        <property type="protein sequence ID" value="PRC90699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90699">
        <property type="protein sequence ID" value="PRC90699"/>
        <property type="gene ID" value="S2091_4592"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HlyD_D23" evidence="2">
        <location>
            <begin position="30"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="105"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC90699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="325" mass="35243" checksum="F4565F66B8DE56A3" modified="2018-07-18" version="1">MNKKIVVAIILVTVCLVAGFALYQTRHQSEELQFSGNVDIRQVNVAFRVGGRLKTLQVDEGAQVKAGDVLGELDDQPYRIALADAQANNAALEAHNMLYKKGYRKEDIQQAKANLNTRLAALLNASQLLQRQQKITGTGAGSQRSLDDAQSGYDQATAQVDAARQQYLALSHGYRPEEIAEVAANRQRAAAQLNNAELQLADTVLKAPSNGIILTRAVEPGSMLTAGSTALTLSLTEPVWVRAYVAEPDLGKVAPGTRVKVITDSRKEPYNGVIGFVSPTAEFTPKNVETSDLRTALVYRLRVIVENADTQLRQGMPVTIKLAAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSN2</accession>
    <name>A0A2S9GSN2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ProV: glycine betaine/L-proline transport ATP binding subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_4599</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000038">
        <property type="protein sequence ID" value="PRC90706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90706">
        <property type="protein sequence ID" value="PRC90706"/>
        <property type="gene ID" value="S2091_4599"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031460">
        <property type="term" value="P:glycine betaine transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005892">
        <property type="entry name" value="Gly-betaine_transp_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01186">
        <property type="entry name" value="proV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-1278">Translocase</keyword>
    <feature type="domain" description="ABC transporter" evidence="7">
        <location>
            <begin position="47"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="80"/>
            <end position="87"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC90706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="424" mass="46861" checksum="B0B6E4F63ABD0A69" modified="2018-07-18" version="1">MSKATDWFVVAVNGGNFLVSVEKLAIKNVYKIFGDQPEQAMQLVREGKNKDQIFAQTGQTLGVNNASLSINEGEIFVIMGLSGSGKSTLVRLLNRLIEPTAGEIWVNGRDITKLTARQLREFRRTEISMVFQSFALMPHLTVVDNVAFGLELAGQSAKSRHEAALLALDKVGLTARANSYPDELSGGMQQRVGLARALANSSQILLMDEAFSALDPLIRTEMQDELVKLQEQDKRTIIFISHDLDEAIRIGNRIAIMQGGVVVQVGTAEEILRNPANDYVRSFFKGVDATSVLSAADIARKTQVNIIDHRGMGVHGALEQLRQNDREYGYVIRPDQRLLGIVSVDTLRRVAQSSPNPKLQDAFLPDILTISHDTHINNLYEPLAHYPYGLPVLDERGCYRGSVTRNSLLEFLHQQAAQTGTSQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSR0</accession>
    <name>A0A2S9GSR0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Prolipoprotein diacylglyceryltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_4507</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Lgt family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000036">
        <property type="protein sequence ID" value="PRC90759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90759">
        <property type="protein sequence ID" value="PRC90759"/>
        <property type="gene ID" value="S2091_4507"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008961">
        <property type="term" value="F:phosphatidylglycerol-prolipoprotein diacylglyceryl transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042158">
        <property type="term" value="P:lipoprotein biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001640">
        <property type="entry name" value="Lgt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30589">
        <property type="entry name" value="PTHR30589"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01790">
        <property type="entry name" value="LGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="72"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="110"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="228"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="258"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC90759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="300" mass="32555" checksum="3E8F9430838C420C" modified="2018-07-18" version="1">MSFPYLSDLVKALTGYDLPLPLPMFGLCVAAAMLVAASFLKRELGRLHAIGKIGVAQVRGVATPPQEIVPDFIAVVMLAGIFGARLFHILEHTDMFLAHPWKMIFTTSGLSIFGGLIFGTLAGVISVIRWKLPIRPMLDAAAPAMMLGYALGRVGCQISGDGDWGIAANMALKPTWLPSWFWAQTYDNNIYGAVIPAPGVYPTSIYETVMALACFGLLWALRKHPFQLGWLFSVYLFLAGLERLVIEQIRVNPMLEFGGIYATQAEFISVGLMILGLLGVALLSKRLPIDALSAGKAKIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSW2</accession>
    <name>A0A2S9GSW2_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNA polymerase sigma factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_4472</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000035">
        <property type="protein sequence ID" value="PRC90809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90809">
        <property type="protein sequence ID" value="PRC90809"/>
        <property type="gene ID" value="S2091_4472"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006950">
        <property type="term" value="P:response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000838">
        <property type="entry name" value="RNA_pol_sigma70_ECF_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01063">
        <property type="entry name" value="SIGMA70_ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="3">
        <location>
            <begin position="19"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="4">
        <location>
            <begin position="126"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC90809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="191" mass="21437" checksum="9402CD66D74C2E73" modified="2018-07-18" version="1">MGSYLNDVDETSRFEAIVLPHLDAAYNLARWLTRNDHDAEDLVQMAFVRAFKFYSGFHGGNARAWLLTIVRHTFYTSLRDQQPENEDVNFDEALHSAHENSGHGSPYDIGCNPENSVENSDTSRVVNQALEKLPQTFREIVILKEIENLSYKEIAEVAGIPIGTVMSRLARGRKLLLNYLQQVGVGGSNGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSW5</accession>
    <name>A0A2S9GSW5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Pyridoxal-dependent decarboxylase conserved domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_4466</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 3">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the group II decarboxylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000035">
        <property type="protein sequence ID" value="PRC90803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90803">
        <property type="protein sequence ID" value="PRC90803"/>
        <property type="gene ID" value="S2091_4466"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016830">
        <property type="term" value="F:carbon-carbon lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019752">
        <property type="term" value="P:carboxylic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002129">
        <property type="entry name" value="PyrdxlP-dep_de-COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00282">
        <property type="entry name" value="Pyridoxal_deC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC90803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="279" mass="29186" checksum="2C430FD90B88A1B1" modified="2018-07-18" version="1">MSDTSSFRLVLERALSHSLAHLDNLEHSPVGASASLETLRDRLAKPLHNEAMPAEQVIDELVADTAGGIMGSAGGRFFGWVIGGSLPAALAADWLTSAWDQNAASYACGPAEAVIEEVCGAWLKDLLGLPSHASFALTSGCQMAHVTALAAARNALLARRNWQVERDGLFGAPKIRILSSDQFHGSITRATRLLGLGTGAVTGLPVNQAGQLEAATLEKALQDTPDTLTIVLLQAGDLNIGAYDSFAELIPLAHRYAHGCMSTAHSACGQTPARAIGIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSX3</accession>
    <name>A0A2S9GSX3_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Type III pantothenate kinase</fullName>
            <ecNumber evidence="6">2.7.1.33</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">PanK-III</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Pantothenic acid kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">coaX</name>
        <name evidence="7" type="ORF">S2091_4468</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>(R)-pantothenate + ATP = (R)-4'-phosphopantothenate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16373"/>
            <dbReference type="ChEBI" id="CHEBI:10986"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29032"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.33"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>NH4(+)</name>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
        </cofactor>
        <cofactor evidence="6">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
        <text evidence="6">A monovalent cation. Ammonium or potassium.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 6">Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 1/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the type III pantothenate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.33" evidence="6"/>
    <dbReference type="EMBL" id="PUGF01000035">
        <property type="protein sequence ID" value="PRC90805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90805">
        <property type="protein sequence ID" value="PRC90805"/>
        <property type="gene ID" value="S2091_4468"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00241">
        <property type="reaction ID" value="UER00352"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004594">
        <property type="term" value="F:pantothenate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015937">
        <property type="term" value="P:coenzyme A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01274">
        <property type="entry name" value="Pantothen_kinase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004619">
        <property type="entry name" value="Type_III_PanK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34265">
        <property type="entry name" value="PTHR34265"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03309">
        <property type="entry name" value="Pan_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00671">
        <property type="entry name" value="baf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 6" id="KW-0173">Coenzyme A biosynthesis</keyword>
    <keyword evidence="4 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 7" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0630">Potassium</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="6">
        <location>
            <begin position="102"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="104"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="6"/>
            <end position="13"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="95"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="128"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="181"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC90805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="253" mass="26478" checksum="9706A7BD574BE38A" modified="2018-07-18" version="1">MLLLIDAGNTRIKWALVDTNQAPQLGEWAQFGSISHQEFADEATPWSGFVVQRAVVSNVAGSALRTQLAESLQRQNIPVEWLVSQAACAGIKNQYRDPTQLGCDRFATAIAAHALFPDQAFIVATCGTATTIDAVTAEGIFIGGMIAPGLKLMAQSLAQNTAQLPSVLASASMTAHFANYTEAAIVSGCLAAQAGAIELAVRNFSAMPDLNTAMPPLCIVSGGAAKYIIPSLGIPHRSVDNLVLIGLQVIASC</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GT28</accession>
    <name>A0A2S9GT28_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phage virion morphogenesis protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4455</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000034">
        <property type="protein sequence ID" value="PRC90874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90874">
        <property type="protein sequence ID" value="PRC90874"/>
        <property type="gene ID" value="S2091_4455"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006522">
        <property type="entry name" value="Phage_virion_morphogenesis"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05069">
        <property type="entry name" value="Phage_tail_S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01635">
        <property type="entry name" value="tail_comp_S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="155" mass="17953" checksum="8DC8B36B33C803A0" modified="2018-07-18" version="1">MSDDLSTIATWAGALLHKLNPAQRRQVMIKIAQDLRRNQAQRITNQQTPDSISYTPRKQRKKLREKQGRIKRQKAAMFNKLRTTKHLKTRQDAQQLTVGFYGRVARIARVHQEGLKDKVAKNGVDYQYPERQLLGFSPGDHTLIKESLLLHLNND</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTF2</accession>
    <name>A0A2S9GTF2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phage major tail tube protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4277</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000031">
        <property type="protein sequence ID" value="PRC90981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90981">
        <property type="protein sequence ID" value="PRC90981"/>
        <property type="gene ID" value="S2091_4277"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006498">
        <property type="entry name" value="Tail_tube"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35861:SF2">
        <property type="entry name" value="PTHR35861:SF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04985">
        <property type="entry name" value="Phage_tube"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01611">
        <property type="entry name" value="tail_tube"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC90981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="169" mass="18411" checksum="FE195729A9AFE985" modified="2018-07-18" version="1">MGLPSKLKDFILFNDGQSYMGKVPELTLPKLARKMEEYRAGGMTGPIMVDFGSEAITLEWTTGGVVVDALKQYAANRHNAVQLRFAGAYQNDDTGEVAAVEVVVRGRHQEIDMGSAKHATETAHKFNTACSYYKLSVDNEVLIELDFMAGVELIGGVDRNAGIRKAIGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTS8</accession>
    <name>A0A2S9GTS8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Acetyl-CoA acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_4138</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the thiolase-like superfamily. Thiolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000028">
        <property type="protein sequence ID" value="PRC91137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91137">
        <property type="protein sequence ID" value="PRC91137"/>
        <property type="gene ID" value="S2091_4138"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002155">
        <property type="entry name" value="Thiolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020617">
        <property type="entry name" value="Thiolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020616">
        <property type="entry name" value="Thiolase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02803">
        <property type="entry name" value="Thiolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00108">
        <property type="entry name" value="Thiolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000429">
        <property type="entry name" value="Ac-CoA_Ac_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thiolase_N" evidence="2">
        <location>
            <begin position="4"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="domain" description="Thiolase_C" evidence="3">
        <location>
            <begin position="263"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC91137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="413" mass="43465" checksum="C835BE0047827063" modified="2018-07-18" version="1">MNEIYIVGVGMTQFGRLLDRTVYDMVNVAVRLALADAGCAAADVGSAYYATMTNGLFQGQTAIPGPIAMRRLGIEGIPVFTVENACASGSSAFNLATLALRAGSCDIALAVGAEKMNIPDKAKMFSAFDGGWDVSTVEENKTTLLAMGDGIIPPPGTVSERPYSVFMDVYAAICRNHMQRYGTTQRQIAAVAAKNHRHSVHNPLSQFREAFSIEQVLASPPICYPLTTLMCSPISDGAAAVVLCNADGLKKLQDAKDRAIRVLASIVQTGSNRSLDEPYKIVAHLAAKKAYEQAGVAPSDVSVAEVHDASAIGEILNAESLMLVPFGEGGPAAERGDFTVGGRIPINPSGGLESKGHPIAATGLGQIHELVTQLRGEAEQRQVSNARIAIQENGGGLFGIEEAVVVVNILAKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTX7</accession>
    <name>A0A2S9GTX7_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Potassium-transporting ATPase KdpC subunit</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">ATP phosphohydrolase [potassium-transporting] C chain</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Potassium-binding and translocating subunit C</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Potassium-translocating ATPase C chain</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">kdpC</name>
        <name evidence="12" type="ORF">S2091_4077</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">The system is composed of three essential subunits: KdpA, KdpB and KdpC.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cell membrane</location>
            <topology evidence="11">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the KdpC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000027">
        <property type="protein sequence ID" value="PRC91182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91182">
        <property type="protein sequence ID" value="PRC91182"/>
        <property type="gene ID" value="S2091_4077"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008556">
        <property type="term" value="F:P-type potassium transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00276">
        <property type="entry name" value="KdpC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003820">
        <property type="entry name" value="KdpC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30042">
        <property type="entry name" value="PTHR30042"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02669">
        <property type="entry name" value="KdpC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001296">
        <property type="entry name" value="K_ATPase_KdpC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00681">
        <property type="entry name" value="kdpC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 11" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9 11" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 11" id="KW-0630">Potassium</keyword>
    <keyword evidence="3 11" id="KW-0633">Potassium transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1 11" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PRC91182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="190" mass="20121" checksum="CEE05DB485D1AD4F" modified="2018-07-18" version="1">MKTLIRPAVSLFVVLSILVGLIYPMLTTGIGKVVFSDQANGSLIEKDHKIVGSSLIGQNFSGPGYFWGRPSATSPMPYNGLNSGGSNFGPSNPAQKAAVADRIKALHDADPSNTQAIPVDLVTASGSGLDPQISPAAINYQLQRVAKARNINPEVLKQLVAKYTEAPQLGIFGEARVNVLQLNLALDIQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTY8</accession>
    <name>A0A2S9GTY8_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NAD_binding_9 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4127</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000028">
        <property type="protein sequence ID" value="PRC91126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91126">
        <property type="protein sequence ID" value="PRC91126"/>
        <property type="gene ID" value="S2091_4127"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038732">
        <property type="entry name" value="HpyO_NAD-binding"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13454">
        <property type="entry name" value="NAD_binding_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD_binding_9" evidence="1">
        <location>
            <begin position="5"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="467" mass="52119" checksum="121D856C1A814593" modified="2018-07-18" version="1">MKTIAIIGAGFSGTVTALNLLRQAEALKAQINVVLIDKAASFGKGLAYATEDDNLVLNVPIGNMSAFADLPDDFLEFCHGMDSSLNHGSFVFRRIYGEYLQLRLREAKSAYTDRLIEMRDFVTGMRPSQGGLILNLQTGAQVAADCVVLAFGHFAPRALSEILGEATFHQRIDQQTYLDNPWDVAALDRLPADKDVLIVGTGHTAMDTLFRLVSSSLARKIYIVSRHGHTPNGHRKAGEFVKLAQLTKSVESTMRSLLSDRPTIRMLFSTIRKLSKQHSEQQGNWRDVINSLRQLTPEIWRALPGSERARFLRHVVYHWDVLRHRLAPVAIRRFEDLLSAGRVEIIAGRIAQFDSIAGDSTICASIRLRGSNRCREFMVGSVINCTGPNYDIHRISNPLVRQLTDAGILQQDELKTGFTVDENYRCSDLPNLHYIGPMLKASYWEAIAVPELRVHSQNLAKIILVSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTZ9</accession>
    <name>A0A2S9GTZ9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Acyl-CoA dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_4137</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000028">
        <property type="protein sequence ID" value="PRC91136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91136">
        <property type="protein sequence ID" value="PRC91136"/>
        <property type="gene ID" value="S2091_4137"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016627">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="SSF47203"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="SSF56645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA_dh_N" evidence="7">
        <location>
            <begin position="7"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_M" evidence="6">
        <location>
            <begin position="126"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_1" evidence="5">
        <location>
            <begin position="237"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC91136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="385" mass="42360" checksum="80B1C22D8E52A3F3" modified="2018-07-18" version="1">MGHVIRTEEQQGAIDGLRRYLDAEVDQVFSKEYRDQFVPKEKMAAIMQKLTEFGLVAGTVSEANGGMGIDWLTMTMLFEEVAATSADLSVPVLINSFGAQMIEKLAPAHLRERYLPGLLNGTSFVSMGISEPDVGSNVLEIKTRARRDGDDYIINGEKTWISNGVYSDFLICTCRTGEDPRRGLTHFLLDRKEHPYETRNIHKIAWNSQSTAQVFLHDVRVPASNMIGNEGAALKNTLSFFERSRVYVAGQGLGIARRALEEAIRYSKDRQQHGKPIAGHQLISAMLAEMATNVDAARLLTYRAASMIEAGVPAEMEAAMAKYFACEAAVKIARQAVQIHGANGLTTDFLVEKLAREAIVAPIPEGTTQIQQLIIGRALTGINAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GU45</accession>
    <name>A0A2S9GU45_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">Argininosuccinate lyase</fullName>
            <shortName evidence="5">ASAL</shortName>
            <ecNumber evidence="3 5">4.3.2.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Arginosuccinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">argH</name>
        <name evidence="8" type="ORF">S2091_4037</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>2-(N(omega)-L-arginino)succinate = fumarate + L-arginine</text>
            <dbReference type="Rhea" id="RHEA:24020"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="ChEBI" id="CHEBI:32682"/>
            <dbReference type="ChEBI" id="CHEBI:57472"/>
            <dbReference type="EC" id="4.3.2.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 5">Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 3/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.3.2.1" evidence="3 5"/>
    <dbReference type="EMBL" id="PUGF01000026">
        <property type="protein sequence ID" value="PRC91252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91252">
        <property type="protein sequence ID" value="PRC91252"/>
        <property type="gene ID" value="S2091_4037"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00068">
        <property type="reaction ID" value="UER00114"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004056">
        <property type="term" value="F:argininosuccinate lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042450">
        <property type="term" value="P:arginine biosynthetic process via ornithine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01359">
        <property type="entry name" value="Argininosuccinate_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.275.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00006">
        <property type="entry name" value="Arg_succ_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029419">
        <property type="entry name" value="Arg_succ_lyase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009049">
        <property type="entry name" value="Argininosuccinate_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024083">
        <property type="entry name" value="Fumarase/histidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020557">
        <property type="entry name" value="Fumarate_lyase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000362">
        <property type="entry name" value="Fumarate_lyase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022761">
        <property type="entry name" value="Fumarate_lyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008948">
        <property type="entry name" value="L-Aspartase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43814">
        <property type="entry name" value="PTHR43814"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14698">
        <property type="entry name" value="ASL_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00206">
        <property type="entry name" value="Lyase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00149">
        <property type="entry name" value="FUMRATELYASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48557">
        <property type="entry name" value="SSF48557"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00838">
        <property type="entry name" value="argH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00163">
        <property type="entry name" value="FUMARATE_LYASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="4 5" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lyase_1" evidence="6">
        <location>
            <begin position="15"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="domain" description="ASL_C2" evidence="7">
        <location>
            <begin position="371"/>
            <end position="439"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012338"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF14698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC91252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="463" mass="51266" checksum="7E21C81B59F5BF7F" modified="2018-07-18" version="1">MTSQFSKKNEAWSARFSEPVSDLVKRYTASVFFDKRLAQVDIQGSLAHAEMLCFKEIINKTDYAEIVRGMAQISTEISANSFTWQLDLEDVHLNIEKRLTEIVGDAGKRLHTGRSRNDQVATDIRLYLRGAIDDILGLLSQFRLALLDLAEQQADTIMPGFTHMQVAQPITFGHHMLAYVEMFGRDAERMVDCRKRVNRLPLGAAALAGTTFPIDRERVAQTLGFEGICANSLDAVSDRDFAIEFCAASALIMTHISRMSEELVIWMSPRIGFIDIADRFCTGSSIMPQKKNPDVPELARGKTGRVNGHLIALLTLMKGQPLAYNKDNQEDKEPLFDTVDTITDTLRIFADMAGGITVKPEAMRAAALQGYATATDLADYLVKKGLPFRDAHEAVAHAVKTCVNKECDLSDLTLEELRVFSTLIDADIFEVLTLEGSVAARDHLGGTAPNQVRAAIARLRAQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUI3</accession>
    <name>A0A2S9GUI3_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 14">Biotin carboxylase</fullName>
            <ecNumber evidence="5 14">6.3.4.14</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12 14">Acetyl-coenzyme A carboxylase biotin carboxylase subunit A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">S2091_3909</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 14">This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 14">
            <text>ATP + hydrogencarbonate + N(6)-biotinyl-L-lysyl-[protein] = ADP + H(+) + N(6)-carboxybiotinyl-L-lysyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13501"/>
            <dbReference type="Rhea" id="RHEA-COMP:10505"/>
            <dbReference type="Rhea" id="RHEA-COMP:10506"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83144"/>
            <dbReference type="ChEBI" id="CHEBI:83145"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.14"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 14">Lipid metabolism; malonyl-CoA biosynthesis; malonyl-CoA from acetyl-CoA: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 14">Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.14" evidence="5 14"/>
    <dbReference type="EMBL" id="PUGF01000024">
        <property type="protein sequence ID" value="PRC91364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91364">
        <property type="protein sequence ID" value="PRC91364"/>
        <property type="gene ID" value="S2091_3909"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00655">
        <property type="reaction ID" value="UER00711"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003989">
        <property type="term" value="F:acetyl-CoA carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004075">
        <property type="term" value="F:biotin carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:2001295">
        <property type="term" value="P:malonyl-CoA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004549">
        <property type="entry name" value="Acetyl_CoA_COase_biotin_COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005481">
        <property type="entry name" value="BC-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011764">
        <property type="entry name" value="Biotin_carboxylation_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005482">
        <property type="entry name" value="Biotin_COase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005479">
        <property type="entry name" value="CbamoylP_synth_lsu-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011054">
        <property type="entry name" value="Rudment_hybrid_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02785">
        <property type="entry name" value="Biotin_carb_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00289">
        <property type="entry name" value="Biotin_carb_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02786">
        <property type="entry name" value="CPSase_L_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00878">
        <property type="entry name" value="Biotin_carb_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51246">
        <property type="entry name" value="SSF51246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="SSF52440"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00514">
        <property type="entry name" value="accC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50979">
        <property type="entry name" value="BC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00866">
        <property type="entry name" value="CPSASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00867">
        <property type="entry name" value="CPSASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10 13 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11 14" id="KW-0092">Biotin</keyword>
    <keyword evidence="14" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="14" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="7 14" id="KW-0436">Ligase</keyword>
    <keyword evidence="14" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="14" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8 13 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Biotin carboxylation" evidence="16">
        <location>
            <begin position="1"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-grasp" evidence="15">
        <location>
            <begin position="120"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00017242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00033786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU365063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="PRC91364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="460" mass="50808" checksum="8FE4B01B3FB7FD4B" modified="2018-07-18" version="1">MFEKILIANRGEIALRIQRACREMGIKTVVVHSEADREAKYVKLADESVCIGPAPSSLSYLNMPAIISAAEVTDAQAIHPGYGFLAENADFAERVEQSGFVFIGPRSESIRLMGDKVSAKHAMIKAGVPCVPGSEGALPDNPKEIVQTARKVGYPVIIKAAGGGGGRGMRVVHTEAALLNAVTMTKTEAGTAFGNPEVYMEKFLENPRHVEIQILADSLGNAVWLGERDCSMQRRHQKVLEEAPAPDIPRKMIEKIGERCAEACRKMGYRGAGTFEFLYENGEFYFIEMNTRVQVEHPVTEMITGIDIVQEQIWVASGEPLRFKQRDVTFKGHAIECRINAEDPFKFIPSPGKITSWHVPGGPGIRVDSHAYDGYTVPPHYDSMIGKVIAYGATREQAIRRMQIALSEMVVEGIQTNIPLHRELMVDARFIEGGTNIHYLEHKLAEKPDLPKASQKNGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GV28</accession>
    <name>A0A2S9GV28_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Multidrug resistance efflux pump</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3674</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000021">
        <property type="protein sequence ID" value="PRC91558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91558">
        <property type="protein sequence ID" value="PRC91558"/>
        <property type="gene ID" value="S2091_3674"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="domain" description="HlyD_D23" evidence="2">
        <location>
            <begin position="49"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="350" mass="38026" checksum="C855084EE80188A9" modified="2018-07-18" version="1">MNNINNREHYVRRLVAITLLLIAAGLLSYVIWRLDTEPRTDDAYVLADTISVTPEINGRIIELPVRDNQAVKKGDILFRIDPRPFELALGKAQATLTALDNEIKLTQRSVNSQQLGAAASKSNIDRAKAAAQQATDTLERMRPLLSNGYVAAEQIDQAETAKKSAQSQLKTAILDADRAQAAVSGVDALVAKRDIIQSEIAMAKLNLEYATVRAPFDGNIIGLRISSGQYVAAGHPIFTLSNTGRWYVVANFRETELANITPGHPVLLYLLSDPSKRFHGVVESIGSGVFPEEGGNDVAGLPRVPRSINWVRVAQRFPVRILVKNPDPAQFRIGASAVAMMSKDAAGTAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GV53</accession>
    <name>A0A2S9GV53_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glutathione S-transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3728</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000021">
        <property type="protein sequence ID" value="PRC91612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91612">
        <property type="protein sequence ID" value="PRC91612"/>
        <property type="gene ID" value="S2091_3728"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00043">
        <property type="entry name" value="GST_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13417">
        <property type="entry name" value="GST_N_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="SSF47616"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GST N-terminal" evidence="1">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="2">
        <location>
            <begin position="86"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="223" mass="25290" checksum="60F2CF9C3A9D179B" modified="2018-07-18" version="1">MIKLYHCMSARSFRPLWMLEELGRPYELKMLHFPPRLLDKSYLAINPLGTVPALVDGATLMTESAAICQYLVARAAPTLLNVDADEPDFGAYLNYLHFGEATLTFPQTIVLRYSRFEPEPRRSQQVADDYAKWFLARLRTLEIRLAQHDYLCADRFTAADISVGYALLLAEHLGLMSRFTPAVLAYWERLRSRDAFLRAIASQERAALEQGVSPVPAPDTLPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GV62</accession>
    <name>A0A2S9GV62_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3725</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000021">
        <property type="protein sequence ID" value="PRC91609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91609">
        <property type="protein sequence ID" value="PRC91609"/>
        <property type="gene ID" value="S2091_3725"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010985">
        <property type="entry name" value="Ribbon_hlx_hlx"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47598">
        <property type="entry name" value="SSF47598"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="95" mass="10671" checksum="16FA78E72387E40E" modified="2018-07-18" version="1">MTTTTIRLSDELKARITAAANHAETTTHNFILQAIAEKTAQEELKRDFDNEAEARYANILATGKAIPWHEMRDYLESRASGKTSAIRPTAKKLVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVA0</accession>
    <name>A0A2S9GVA0_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Bifunctional NAD(P)H-hydrate repair enzyme</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Nicotinamide nucleotide repair protein</fullName>
        </alternativeName>
        <domain>
            <recommendedName>
                <fullName evidence="11">ADP-dependent (S)-NAD(P)H-hydrate dehydratase</fullName>
                <ecNumber evidence="11">4.2.1.136</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="11">ADP-dependent NAD(P)HX dehydratase</fullName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="11">NAD(P)H-hydrate epimerase</fullName>
                <ecNumber evidence="11">5.1.99.6</ecNumber>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name evidence="10" type="primary">nnrE</name>
        <name evidence="9" type="synonym">nnrD</name>
        <name evidence="13" type="ORF">S2091_3593</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8 11">Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.</text>
    </comment>
    <comment type="function">
        <text evidence="9">Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.</text>
    </comment>
    <comment type="function">
        <text evidence="10">Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10 11">
            <text>(6R)-NADHX = (6S)-NADHX</text>
            <dbReference type="Rhea" id="RHEA:32215"/>
            <dbReference type="ChEBI" id="CHEBI:64074"/>
            <dbReference type="ChEBI" id="CHEBI:64075"/>
            <dbReference type="EC" id="5.1.99.6"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 10 11">
            <text>(6R)-NADPHX = (6S)-NADPHX</text>
            <dbReference type="Rhea" id="RHEA:32227"/>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
            <dbReference type="ChEBI" id="CHEBI:64077"/>
            <dbReference type="EC" id="5.1.99.6"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3 9 11">
            <text>(6S)-NADHX + ADP = AMP + H(+) + NADH + phosphate</text>
            <dbReference type="Rhea" id="RHEA:32223"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:64074"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="4.2.1.136"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4 9 11">
            <text>(6S)-NADPHX + ADP = AMP + H(+) + NADPH + phosphate</text>
            <dbReference type="Rhea" id="RHEA:32235"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="4.2.1.136"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10 11">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
        <text evidence="10 11">Binds 1 potassium ion per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the NnrD/CARKD family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the NnrE/AIBP family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6 11">In the C-terminal section; belongs to the NnrD/CARKD family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 11">In the N-terminal section; belongs to the NnrE/AIBP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.136" evidence="11"/>
    <dbReference type="EC" id="5.1.99.6" evidence="11"/>
    <dbReference type="EMBL" id="PUGF01000020">
        <property type="protein sequence ID" value="PRC91655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91655">
        <property type="protein sequence ID" value="PRC91655"/>
        <property type="gene ID" value="S2091_3593"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052855">
        <property type="term" value="F:ADP-dependent NAD(P)H-hydrate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052856">
        <property type="term" value="F:NADHX epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052857">
        <property type="term" value="F:NADPHX epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046496">
        <property type="term" value="P:nicotinamide nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01171">
        <property type="entry name" value="YXKO-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01965">
        <property type="entry name" value="NADHX_dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01966">
        <property type="entry name" value="NADHX_epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000631">
        <property type="entry name" value="CARKD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030677">
        <property type="entry name" value="Nnr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004443">
        <property type="entry name" value="YjeF_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036652">
        <property type="entry name" value="YjeF_N_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01256">
        <property type="entry name" value="Carb_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03853">
        <property type="entry name" value="YjeF_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017184">
        <property type="entry name" value="Nnr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="SSF53613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64153">
        <property type="entry name" value="SSF64153"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00196">
        <property type="entry name" value="yjeF_cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00197">
        <property type="entry name" value="yjeF_nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51383">
        <property type="entry name" value="YJEF_C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51385">
        <property type="entry name" value="YJEF_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 10 11" id="KW-0413">Isomerase</keyword>
    <keyword evidence="9 11" id="KW-0456">Lyase</keyword>
    <keyword evidence="10 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 11" id="KW-0520">NAD</keyword>
    <keyword evidence="9 11" id="KW-0521">NADP</keyword>
    <keyword evidence="9 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10 11" id="KW-0630">Potassium</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YjeF N-terminal" evidence="12">
        <location>
            <begin position="8"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="NADPHX" evidence="10">
        <location>
            <begin position="55"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="56"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="120"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="157"/>
        </location>
        <ligand>
            <name>(6S)-NADPHX</name>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="160"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="258"/>
        </location>
        <ligand>
            <name>(6S)-NADPHX</name>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="313"/>
        </location>
        <ligand>
            <name>(6S)-NADPHX</name>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="367"/>
        </location>
        <ligand>
            <name>(6S)-NADPHX</name>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="404"/>
            <end position="408"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="433"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="434"/>
        </location>
        <ligand>
            <name>(6S)-NADPHX</name>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00001241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00006001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00009524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00025153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR017184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PRC91655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="496" mass="51408" checksum="B9391174FF6DCBB1" modified="2018-07-18" version="1">MLYTIKQLRQIEQSALSSLEPGTLMRAAGKAAAQAALQLLKTPNQAVLILVGPGNNGGDALEAAVHLANAGHQIFVLHSPSKTARSPSGQQAFNQAQACTQINWLASDAPLQDNYALVIDGLFGIGLTQLAQQKISPALQKQITQCNAMSCPILALDVPSGLDADTGTIITNIAIQASHTITFIADKAGLHTGDGQDYAGLVEVADLDIALEYFPVSVSELNKPALFPDIAKPRRHNSHKGSNGTVAVIGGAVGMQGAVILAARAALYSGAGRTVASFVEATPNFDAQQPELMCRPAQQVQFNPDTVVVIGPGLGNSIASFDLVSRALLSTSPLIIDADALNLMAQQPALHALCNGRDKLSTLLTPHPLEAARLLGCSVEIIQADRISAAKKLARQYSSVVILKGSGSIIAHPDGNMVINPTGNAGLASGGTGDVLGGVCGALMAQHKNMWQAALAATYLHGTAADSLVALGIGPIGLCASELLVEIRKQLNTLLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVS6</accession>
    <name>A0A2S9GVS6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3565</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000019">
        <property type="protein sequence ID" value="PRC91810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91810">
        <property type="protein sequence ID" value="PRC91810"/>
        <property type="gene ID" value="S2091_3565"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009323">
        <property type="entry name" value="DUF979"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06166">
        <property type="entry name" value="DUF979"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="97"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="130"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="170"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="207"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="232"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="257"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="296"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="316" mass="33447" checksum="55EF762C2210FF67" modified="2018-07-18" version="1">MMFTLDYFYILLGCMLAAIAVISVQDKANPRRFTTGVFWALYATVYLIGERMPPIAVGILVVVMALIAGFGGVAMGKYSELSGAGKQASASKLGNRLFIPALIIPLTTIIGSVLLNHVKIADVFLLDQKNITLVSLGFGCVFALACACWITRSSPLQGLRESRRLIDSMGSVVVLPHILAVLGLLFIDAGVGKAVAHLATAYINMDYKLVAVAVYCLGMALFTVIMGNGFAAFPVMAGGVGIPILVGIYHANPAVMAAIGMFSGYCGTLMTPMAANFNIVPVALLNLPDKNAVIKAQLPTALPLLAVNILLLYFLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GW29</accession>
    <name>A0A2S9GW29_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative F0F1-ATPase subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3271</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000017">
        <property type="protein sequence ID" value="PRC91929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91929">
        <property type="protein sequence ID" value="PRC91929"/>
        <property type="gene ID" value="S2091_3271"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011744">
        <property type="entry name" value="ATPase_gene1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032820">
        <property type="entry name" value="ATPase_put"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09527">
        <property type="entry name" value="ATPase_gene1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02230">
        <property type="entry name" value="ATPase_gene1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="78"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="118" mass="13319" checksum="967C3788D41EAB7E" modified="2018-07-18" version="1">MSNKPEQPETIVETTFSRKVGEQEMRKLRAQRRTIQGVWFGLGMMGLVGWSVVVPTLVGAAIGIWIDKHYPAGHSWTLTLLITGLCLGCFNAWHWVAKEDSAIHKEQSEPVEKESRDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GW32</accession>
    <name>A0A2S9GW32_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">ATP synthase subunit alpha</fullName>
            <ecNumber evidence="14">7.1.2.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">ATP synthase F1 sector subunit alpha</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="14">F-ATPase subunit alpha</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">atpA</name>
        <name evidence="18" type="ORF">S2091_3266</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 14">Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>ATP + 4 H(+)(in) + H2O = ADP + 5 H(+)(out) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:57720"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="7.1.2.2"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="13">F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="14">Cell membrane</location>
            <topology evidence="14">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 14">Belongs to the ATPase alpha/beta chains family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.1.2.2" evidence="14"/>
    <dbReference type="EMBL" id="PUGF01000017">
        <property type="protein sequence ID" value="PRC91924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91924">
        <property type="protein sequence ID" value="PRC91924"/>
        <property type="gene ID" value="S2091_3266"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045261">
        <property type="term" value="C:proton-transporting ATP synthase complex, catalytic core F(1)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd18113">
        <property type="entry name" value="ATP-synt_F1_alpha_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.150.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01346">
        <property type="entry name" value="ATP_synth_alpha_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017710">
        <property type="entry name" value="Alt_ATP_synth_F1_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023366">
        <property type="entry name" value="ATP_synth_asu-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000793">
        <property type="entry name" value="ATP_synth_asu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038376">
        <property type="entry name" value="ATP_synth_asu_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005294">
        <property type="entry name" value="ATP_synth_F1_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020003">
        <property type="entry name" value="ATPase_a/bsu_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004100">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036121">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000194">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_nucl-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00006">
        <property type="entry name" value="ATP-synt_ab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00306">
        <property type="entry name" value="ATP-synt_ab_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02874">
        <property type="entry name" value="ATP-synt_ab_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50615">
        <property type="entry name" value="SSF50615"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03324">
        <property type="entry name" value="alt_F1F0_F1_al"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00962">
        <property type="entry name" value="atpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00152">
        <property type="entry name" value="ATPASE_ALPHA_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12 14" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="7 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 14" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="11 14" id="KW-0139">CF(1)</keyword>
    <keyword evidence="6 14" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="9 14" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 14" id="KW-1278">Translocase</keyword>
    <keyword evidence="3 14" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ATP-synt_ab_N" evidence="17">
        <location>
            <begin position="32"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-synt_ab" evidence="15">
        <location>
            <begin position="156"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-synt_ab_C" evidence="16">
        <location>
            <begin position="378"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <begin position="176"/>
            <end position="183"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="site" description="Required for activity" evidence="14">
        <location>
            <position position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00026013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF00306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF02874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="PRC91924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="515" mass="55978" checksum="30A6498F4B591A7B" modified="2018-07-18" version="1">MSELPDTLLAAVGDTFAHMSQVREGYAHQLAVREVGIVTAVSTGIATIVGLPTIGFEELIRFPNGLRGIAFNIDANEIGVVLLGDYTQLQTGDEVERTGRVMDVAVGEELLGRVINPLGRPLDEQGPISTSQRLPIERNAKAIMDRAPVTTPLQTGIKVIDALVPIGRGQRELILGDRQTGKTAIALDAILNQRGQNVLCIYCAIGQRASSVAKVVADLRSHGAMEYTVVMVSEGNDAPGLTYIAPYAATSIAEHFMEAGRDVLIVYDDLTQHARAYRELSLLLRRPPGREAFPGDVFYIHSRLLERSTHLRTELGGGSLTSLPIIETEAQDIAAYIPTNLISITDGQLYLSPTLFELGMLPAIDVAKSVSRVGGKAQLGAYRAVAGTIKLAYSQFEELETFSRFGTRLDDSSRNIIDHGNRIRACLKQPIYSPLTVPKQICILFALTSGLFDTVPLERMPEAEQALSLAAQEIPDDVCQRFTTQKKLSDEDRATIQRIAKTALTPFVLTATSDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWA0</accession>
    <name>A0A2S9GWA0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3335</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000017">
        <property type="protein sequence ID" value="PRC91993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91993">
        <property type="protein sequence ID" value="PRC91993"/>
        <property type="gene ID" value="S2091_3335"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="125" mass="14635" checksum="4BB3EB5941A25C22" modified="2018-07-18" version="1">MIPPHGEFEACRSGVARQPVTFFASPKKVTQKRRPRYFGNPDFSEGKREKFETRLRLKQRTFLILFPSEKPAELEVGVGQKQRQLQNQLQNQLQLQNQLQNQLQLQLQLQLQLQQQHIQISTSPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWM3</accession>
    <name>A0A2S9GWM3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3258</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000016">
        <property type="protein sequence ID" value="PRC92123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92123">
        <property type="protein sequence ID" value="PRC92123"/>
        <property type="gene ID" value="S2091_3258"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021352">
        <property type="entry name" value="DUF2971"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11185">
        <property type="entry name" value="DUF2971"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="266" mass="31562" checksum="FD0890BD44009F53" modified="2018-07-18" version="1">MTNEINISHMLPKLLYKYRKDDDRSWDALKNCKIYFSNRNGFNDLLDSRLELVTPTIPELELLDLQNRITVFGQRSQFPQFVIKKKVTLAGQKILDTYRQMVENLLDSYQFYCLCAIGDSIAMWSYYADDHKGFCIEFNTTVIRGDQVQYKIGQPKIKLIDHLKNQNDQEIGKAVWEGLRTKELKWDHEEEYRLQPSNEMKKLHTKVNADTSFAIYQPEWVESIIFGYKMSEERRQFFIQNYPHKVKFKHFVRNGITLAVEDLPQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWS0</accession>
    <name>A0A2S9GWS0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3076</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92160">
        <property type="protein sequence ID" value="PRC92160"/>
        <property type="gene ID" value="S2091_3076"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004536">
        <property type="term" value="F:deoxyribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01310">
        <property type="entry name" value="TatD_DNAse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018228">
        <property type="entry name" value="DNase_TatD-rel_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015991">
        <property type="entry name" value="Hydrolase_TatD-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001130">
        <property type="entry name" value="TatD-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01026">
        <property type="entry name" value="TatD_DNase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005902">
        <property type="entry name" value="DNase_TatD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00010">
        <property type="entry name" value="TIGR00010"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01137">
        <property type="entry name" value="TATD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01091">
        <property type="entry name" value="TATD_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="259" mass="28790" checksum="84E9F420C545371B" modified="2018-07-18" version="1">MFIDSHCHLDFPELSARLPEILATMEANQVGRALCVAVDLPDFPRVLNLAETYPHLYASVGVHPDYVDTPEPTVEQLVTLSNHPKVIAIGETGLDYFRLTGDLEWQRNRFRTHIEASRITGKPLIIHTRASAEDTIKIMRESGAGIEQGGAGGVMHCFTETLDVALAAVDMGFYISFSGILTFKSAKQIQEVAKALPLERILIETDSPYLAPIPHRGKMNEPGWVKHVAEYLADLKQIPLAQVEQQTTENFFTLFKHAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWU5</accession>
    <name>A0A2S9GWU5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3111</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92195">
        <property type="protein sequence ID" value="PRC92195"/>
        <property type="gene ID" value="S2091_3111"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012434">
        <property type="entry name" value="DUF1631"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07793">
        <property type="entry name" value="DUF1631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="279"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="374"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="123"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="279"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="328"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="375"/>
            <end position="401"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="919" mass="100180" checksum="BAE0EF1461C1FA8C" modified="2018-07-18" version="1">MGMDRNTLLNSSRATFLSTFNSLIEGVVRRSFEQLYDKADKSINSQMQRHMLDARTLLMRNDVALIKNIVGKLEALLNRSFQTAYDTFRPSFFTAGKASSLALMDLNTFEDDLRVDIITSRFRSEAEEQLRDLNIRIAILFERNDIAERENPFRPYLLTRAIVLGVEAINAEAELAVILTDQLAEELGLNIVSLYESINQHLSECGVAAQLQFKPQRMPSDLTNPVGYEAEGNAANVGANEASAHPRHHPHPANKAESAANKAGKIEHLLQMVKHGNPQQMQSGASYDSFNEGSFNGGGGASSGSGRTGVGGFGGSGGGMAGGSHAASPMSHGSSQGSGGGLLNHAGSAVSGWLEGAQEVGDALRRVFLGGTSGGASAHGNSSGNEYGNAAQGNSMHGEGHDQGQSGGAGHFKSISPQLSHALHSPVPSTGEMTGVDGEVRNLIIESRDSLNAMAADQHEKMTIDIVAMLFEFILKDHQVPAEVRAQLGRLQFSVLKMALMDSALLTKKSHPARLLVNRIGSISVGLQQIDPTGERISAEICRIVEELLASDSESPELFSKMLDQLDVFIARELLASNTNVEQAVNVVINAEHRSERFSHASAKLEKMLDGIAVTPYLRRFLLDTWSHVIERVERNPHVDSTRFRLLVPNLLWSILPKASHDDRAMLLQVIPGLVPVLREGMSLVAWLPEHQQELLNWLVDAHTTVMRAAASIDPVVSLVEVQRHFHEFVYPDDEPLPALPVTYKGDVNRSFLDEAIRELELELHAVGVLQDLDVKPELIDPDHHYEEEFVSKSEPETEFDTTSSGFYTTVGAIEKNSAAKEAEGSETDILDRLRSGVIVEINLSGTPTKGRLNWISPNSSNLILTVNGQEAPSIISVRMFRRMLKSSRARFVEVAPLFERAVQSLLESADLVDLAHAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWV1</accession>
    <name>A0A2S9GWV1_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">LexA repressor</fullName>
            <ecNumber evidence="12">3.4.21.88</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">lexA</name>
        <name evidence="16" type="ORF">S2091_3052</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>Hydrolysis of Ala-|-Gly bond in repressor LexA.</text>
            <dbReference type="EC" id="3.4.21.88"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="12">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 12 13">Belongs to the peptidase S24 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.88" evidence="12"/>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92136">
        <property type="protein sequence ID" value="PRC92136"/>
        <property type="gene ID" value="S2091_3052"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009432">
        <property type="term" value="P:SOS response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06529">
        <property type="entry name" value="S24_LexA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00015">
        <property type="entry name" value="LexA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006200">
        <property type="entry name" value="LexA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039418">
        <property type="entry name" value="LexA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036286">
        <property type="entry name" value="LexA/Signal_pep-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006199">
        <property type="entry name" value="LexA_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006197">
        <property type="entry name" value="Peptidase_S24_LexA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015927">
        <property type="entry name" value="Peptidase_S24_S26A/B/C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01726">
        <property type="entry name" value="LexA_DNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00717">
        <property type="entry name" value="Peptidase_S24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00726">
        <property type="entry name" value="LEXASERPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51306">
        <property type="entry name" value="SSF51306"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00498">
        <property type="entry name" value="lexA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 12 13" id="KW-0068">Autocatalytic cleavage</keyword>
    <keyword evidence="4 12" id="KW-0227">DNA damage</keyword>
    <keyword evidence="10 12" id="KW-0234">DNA repair</keyword>
    <keyword evidence="3 12" id="KW-0235">DNA replication</keyword>
    <keyword evidence="8 12" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 12 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 12" id="KW-0678">Repressor</keyword>
    <keyword evidence="11 12" id="KW-0742">SOS response</keyword>
    <keyword evidence="9 12" id="KW-0804">Transcription</keyword>
    <keyword evidence="7 12" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="LexA_DNA_bind" evidence="15">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S24" evidence="14">
        <location>
            <begin position="92"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="12">
        <location>
            <begin position="28"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="active site" description="For autocatalytic cleavage activity" evidence="12">
        <location>
            <position position="134"/>
        </location>
    </feature>
    <feature type="active site" description="For autocatalytic cleavage activity" evidence="12">
        <location>
            <position position="171"/>
        </location>
    </feature>
    <feature type="site" description="Cleavage; by autolysis" evidence="12">
        <location>
            <begin position="99"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU003991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF01726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="PRC92136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="213" mass="23355" checksum="AF870EA02A88E3D6" modified="2018-07-18" version="1">MQKLTARQEQILNLIRDAIQNTGFPPTRAEIATELGFRSANAAEEHLQALARKKVIELTPGTSRGIRLCESIQSRASEQVSAISSTPQLVLPLVGRVAAGSPMLSEEHIEASYNVDPSLFSTRPDYLLKVRGMSMRDVGILEGDLLAVKKTSHANNGQIVVARIGDEVTVKRYKKTGSLIELFPENPDYSVIKVETEDFALEGLAVGLLRSWN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GX69</accession>
    <name>A0A2S9GX69_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2974</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92315">
        <property type="protein sequence ID" value="PRC92315"/>
        <property type="gene ID" value="S2091_2974"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="52"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="74" mass="8204" checksum="D80E9E0A03CD4867" modified="2018-07-18" version="1">MDIQVIRNLVLAAIAKNDGLWSWYQIDRALATERPEISAVLIPALSTLESEGKINSRQSNEHPSLPRYSITANG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GX89</accession>
    <name>A0A2S9GX89_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2993</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92334">
        <property type="protein sequence ID" value="PRC92334"/>
        <property type="gene ID" value="S2091_2993"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025948">
        <property type="entry name" value="HTH-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13276">
        <property type="entry name" value="HTH_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00665">
        <property type="entry name" value="rve"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13333">
        <property type="entry name" value="rve_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50994">
        <property type="entry name" value="INTEGRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase catalytic" evidence="1">
        <location>
            <begin position="71"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="247" mass="28970" checksum="3E0CED41EA0CF717" modified="2018-07-18" version="1">MVKDKYADLKKHIRTIYARHKGRYGYRRITASIKQLGVNVNHKTVQRLMAELGLKSLVRIKKYRSYKGSVGRIAPNLLQRQFVAANANQKWVTDVTEFNVAGEKLYLSPILDLYNGEIIAYETSRRPVFKMVSDMLKKAWVKLKPDDKPMLHSDQGWQYQMSAYQRILEQRQVVQSMSRKENCLDNAAMESFFGVLKSEYYYLNKFKSVEELEKGLANYIRYYNYDRIKLKLKGLSPVQYRNQPSVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXF2</accession>
    <name>A0A2S9GXF2_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Fructose-1,6-bisphosphate aldolase</fullName>
            <shortName evidence="8">FBP aldolase</shortName>
            <ecNumber evidence="8">4.1.2.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_2779</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 8">Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate</text>
            <dbReference type="Rhea" id="RHEA:14729"/>
            <dbReference type="ChEBI" id="CHEBI:32966"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="4.1.2.13"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="7">Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="8">One is catalytic and the other provides a structural contribution.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 8">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 4/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 8">Belongs to the class II fructose-bisphosphate aldolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.13" evidence="8"/>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92404">
        <property type="protein sequence ID" value="PRC92404"/>
        <property type="gene ID" value="S2091_2779"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00183"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004332">
        <property type="term" value="F:fructose-bisphosphate aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00947">
        <property type="entry name" value="TBP_aldolase_IIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000771">
        <property type="entry name" value="FBA_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006412">
        <property type="entry name" value="Fruct_bisP_Calv"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01116">
        <property type="entry name" value="F_bP_aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001359">
        <property type="entry name" value="F_bP_aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00167">
        <property type="entry name" value="cbbA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01521">
        <property type="entry name" value="FruBisAldo_II_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00602">
        <property type="entry name" value="ALDOLASE_CLASS_II_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00806">
        <property type="entry name" value="ALDOLASE_CLASS_II_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="8" id="KW-0456">Lyase</keyword>
    <keyword evidence="7 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 8" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Dihydroxyacetone phosphate binding" evidence="6">
        <location>
            <begin position="233"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Dihydroxyacetone phosphate binding" evidence="6">
        <location>
            <begin position="275"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="5">
        <location>
            <position position="83"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="84"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="105"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="142"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="198"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="199"/>
        </location>
        <ligand>
            <name>dihydroxyacetone phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="232"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR001359-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR001359-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR001359-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU365019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC92404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="354" mass="38561" checksum="C2FD1D3005B670BF" modified="2018-07-18" version="1">MALVSMRQLLDHAAEYSYGIPAFNVNNLEQVSAIMQAADESGSPVIMQASAGARKYAGEAFLRHLISAAVEAYPHIPVVMHQDHGQSPAVCMAAIKSGFTSVMMDGSLMPDGKSVASYEYNVEVSRKVVEFSHSIGVTVEAELGVLGSLETMMGDKEDGHGADGKMTREQLLTDVTQAADFVKQTQCDALAIAIGTSHGAYKFSRKPTGDILAIDRIREIHARIPNTHLVMHGSSSVPQELLAEIRQFGGDMKETYGVPVEEIQEGIKHGVRKINIDTDIRLAMTGAIRRYLIENPTKFDPRDYLKPAREAAMLVCKARFLSFGCEGQAGKIKPIPLEKIAEKYKQGTLAQIVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXL2</accession>
    <name>A0A2S9GXL2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2837</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92462">
        <property type="protein sequence ID" value="PRC92462"/>
        <property type="gene ID" value="S2091_2837"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="51" mass="6151" checksum="2B3CD1BD028DC5DF" modified="2018-07-18" version="1">MPTKEQIRFYMQERQIEKLPPPSTAEIRRRLGWDLIADSRVKLKIRNVKIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXU7</accession>
    <name>A0A2S9GXU7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2905</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92530">
        <property type="protein sequence ID" value="PRC92530"/>
        <property type="gene ID" value="S2091_2905"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="132" mass="14654" checksum="D3F21B4A19F91DB6" modified="2018-07-18" version="1">MPTNNPQLSTPKDLFRALTQVWVSDTASPPDSLSPQSPAKNHCSVTSLIVQDYFGGEILSTKTSGGTHFYNRINGIKWDLTVSQFGEPEPYDDMLSSRVLALRDTSDHKYNLLTTRLKECAGKIRSTSYPDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXU9</accession>
    <name>A0A2S9GXU9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2594</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92539">
        <property type="protein sequence ID" value="PRC92539"/>
        <property type="gene ID" value="S2091_2594"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="101" mass="11501" checksum="D367C7F280820FBA" modified="2018-07-18" version="1">MTNLLELESDEIDYDPNNLLDTLIKQLHLKNDAALSRALEVAPPVISKIRHRRLPVGASLLIRMHEISDLSIKDLRALMGDRRAKFRISDKQFKPKADGTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXX5</accession>
    <name>A0A2S9GXX5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CAAX protease self-immunity</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2630</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92575">
        <property type="protein sequence ID" value="PRC92575"/>
        <property type="gene ID" value="S2091_2630"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071586">
        <property type="term" value="P:CAAX-box protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003675">
        <property type="entry name" value="Rce1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02517">
        <property type="entry name" value="Rce1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="79"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="131"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="159"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="191"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="223"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="247"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="274"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="294" mass="31903" checksum="69A6BE9D75BC78CE" modified="2018-07-18" version="1">MASQTSIFITFVLLALAICSAWLKPIHINERFILPPWVLFFIASMVSGLVVGVLSPLAIVELGIFCGAAYLAQIPNQKFAQRFIFGSVTAIIALALAMHKLPGFNNPVIISSMTLSAGAATFTQYANFDKGVVGLILLAFLCSRANTLPEWAKLLKQTFPIALITTVAVLGVAIGLDYVKPDFKITQTTALFLGANLFFTVIAEEAFFRGFLQNRLSSVLTRFRYGQLIAIICSALLFGAVHAGGGITIVLLASIAGFGYAYAYYVTRRIEAPIIVHFVLNAVHFIGFTYPHLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXX6</accession>
    <name>A0A2S9GXX6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="9">ABC-type sugar transport systems ATPase component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_2616</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92561">
        <property type="protein sequence ID" value="PRC92561"/>
        <property type="gene ID" value="S2091_2616"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008643">
        <property type="term" value="P:carbohydrate transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03301">
        <property type="entry name" value="ABC_MalK_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015855">
        <property type="entry name" value="ABC_transpr_MalK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008995">
        <property type="entry name" value="Mo/tungstate-bd_C_term_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040582">
        <property type="entry name" value="OB_MalK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17912">
        <property type="entry name" value="OB_MalK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50331">
        <property type="entry name" value="SSF50331"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="5" id="KW-1278">Translocase</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="8">
        <location>
            <begin position="4"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="36"/>
            <end position="43"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC92561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="358" mass="39875" checksum="0F1A1CAA89F337EA" modified="2018-07-18" version="1">MAAVQLKQIYKKYDDTQVLHGIDLDIADGEFVVLVGPSGCGKSTLMRMVAGLESISDGDFYIDGKRANDLPPQQRNIAMVFQSYALYPHLTVYENIAFGPRLRKEPESSFGPRIKAAAAMLNLSPYLQRLPKALSGGQRQRVAMGRAVVREPALFLFDEPLSNLDAKLRVQMRAEIKALHQRLKNTVIYVTHDQIEAITMGDRIVVMNAGKIEQVGKPLDIYDRPANLFVAGFIGSPSMNFIAGTVQIDANQPSLITANDIKIKLPQLDLKAGQKITIGIRPEHIRIERTNNSSNIKLRLDIIEPTGSETYLYGKIDHAPCCIALRERLNFAADDEIQANLPIEHLHVFDTETTCRIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXY0</accession>
    <name>A0A2S9GXY0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NmrA-like family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2891</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92516">
        <property type="protein sequence ID" value="PRC92516"/>
        <property type="gene ID" value="S2091_2891"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008030">
        <property type="entry name" value="NmrA-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05368">
        <property type="entry name" value="NmrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NmrA" evidence="1">
        <location>
            <begin position="9"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="364" mass="40954" checksum="833088A31856C29B" modified="2018-07-18" version="1">MSSPIISTIFIIGGTGAQGIPIIRALVDDKKYAVRVLTRDATSRRAKALLELPNVSTLEGSFADEDILRAGFRGCDGAFINIDGFNTGEKTEIYWAIRSYEIAIEEGVKFFVYGNLDYVLKLSGYDSTFRTGHYDGKGRVGEWIQFQNQANRERMGAAIFTSGPYMEMAMSPMTPMTPTLEQGVVTWRVPLGEGAVPHVALEDCGYYVRWLFDHQERANGMNLEVAIEHVRYADLAAAFEKVTGHPAQYIDTNLDAYWDGSLKAAANAPAGYNANLNDKSTMTFRDNFTGFWNVWKHCIVKRDYALLDEIHPNRIKSVDQWLRREDELGRALGKGSLWDRIQPENFRNETPILKVSEDGRKGKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GY16</accession>
    <name>A0A2S9GY16_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Phage integrase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_2670</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92615">
        <property type="protein sequence ID" value="PRC92615"/>
        <property type="gene ID" value="S2091_2670"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002104">
        <property type="entry name" value="Integrase_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010998">
        <property type="entry name" value="Integrase_recombinase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00589">
        <property type="entry name" value="Phage_integrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51898">
        <property type="entry name" value="TYR_RECOMBINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyr recombinase" evidence="3">
        <location>
            <begin position="166"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC92615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="352" mass="40287" checksum="54F0F69A9F974BB0" modified="2018-07-18" version="1">MRPKSSSRDLPPRMLRRTKTLASGKVWESFYYNGRDESGKRKEIPLGNDINEAKRKWAEFESVPVADDVKIMRVIFNRYVKDIFPMKAARTQKDNGHEIKQLRAVFDSAPIDAITPQHIAQYRDKRTAKVRANRELALLSHVFNMAREWGYTAKENPCRGIRKNKEVPRDFYADAEVWDAVYACAKEELKDAMDIAYLTGQRPADVLKMRLADINASAISVKQNKTGKFLRILLNDEFGNRSALGQTIDAIRRRDKKVLSLSPIALPNGQPMNAYTLRTRFESSREQAAKTAKETNPELSERIKKFQFRDIRPKAASEIKDLGDASKLLGHTDKQITETVYRRVGESVKPTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GY41</accession>
    <name>A0A2S9GY41_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Big_5 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_2631</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ice-binding protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92576">
        <property type="protein sequence ID" value="PRC92576"/>
        <property type="gene ID" value="S2091_2631"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014755">
        <property type="entry name" value="Cu-Rt/internalin_Ig-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021884">
        <property type="entry name" value="Ice-bd_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032812">
        <property type="entry name" value="SbsA_Ig"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13205">
        <property type="entry name" value="Big_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11999">
        <property type="entry name" value="Ice_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015584430" description="Big_5 domain-containing protein" evidence="4">
        <location>
            <begin position="21"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="domain" description="Big_5" evidence="5">
        <location>
            <begin position="62"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="53"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF13205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC92576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="406" mass="40821" checksum="52C7996D527AFA5A" modified="2018-07-18" version="1">MNHCKSLFKPLAWTTTLMLAALLTGCGSGAGTNDSISSSDKSVTQNAILPGTPISPGANSINAPYVSSSNPSNGSTNVPTSTNTSNNIVTGTIVMATFSQPMNPATLNSSPAGHLHTFTLKTTSGNNVPGTVAMDATNTIATFTPSASALMTKTSYTATITTAASSIGGTAITNPVVWSFTTNPIASTSQAPVNLGTAGTFVILSKTGITDVHASAVVGNVGTSPITGAALLLSCGEVTGTIYVVDASGPLPCSVKAPSLLTVAVGDMGSAYLDAQGRKSPNFTELGAGEIGGLTLAPGLYKWSSNVSISTDVTLSGGPNDVWIFQIAGQLKQANAQRVNLAGGALAKNIFWQVAGNVSIGTTAHFEGVAMGKALIAAETDASVNGRLLAQTAVTLQMNAITQPAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GY84</accession>
    <name>A0A2S9GY84_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF4224 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2671</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92616">
        <property type="protein sequence ID" value="PRC92616"/>
        <property type="gene ID" value="S2091_2671"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025319">
        <property type="entry name" value="DUF4224"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13986">
        <property type="entry name" value="DUF4224"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4224" evidence="1">
        <location>
            <begin position="16"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="83" mass="9007" checksum="1271A904709E69E2" modified="2018-07-18" version="1">MSAIFEMQIDSETLAVDELAKITGSSRKGDQIEWLSCNGWTFHKNKSGEAIVGRLYARLKLAGISPASLTTSGGWSPDFSSVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYD2</accession>
    <name>A0A2S9GYD2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2459</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92729">
        <property type="protein sequence ID" value="PRC92729"/>
        <property type="gene ID" value="S2091_2459"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="168" mass="18806" checksum="2794E27608840604" modified="2018-07-18" version="1">MVLSIGEGGMVIDESENILDDFSQAFADRLFSLFPEWRMLQKIERASDGSNYLSLEIAAPAEANAVCGLTVTTENNEVTIGFDYYHGHFFDQVGNGTYLGADYALYFLSQILNEEIFFTSWWIGDQLLAFSTIENGKVLMDDALVGEYGRVRIRSWNGSRNSDINATV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYH7</accession>
    <name>A0A2S9GYH7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Flavoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2493</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92763">
        <property type="protein sequence ID" value="PRC92763"/>
        <property type="gene ID" value="S2091_2493"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004792">
        <property type="entry name" value="BaiN-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023166">
        <property type="entry name" value="HI0933-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42887">
        <property type="entry name" value="PTHR42887"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00275">
        <property type="entry name" value="TIGR00275"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="398" mass="43346" checksum="CB1EE5D577352B6E" modified="2018-07-18" version="1">MVKQIDVVVIGAGAAGLMCAAVAGQRGRRVVLIDHASVLAEKIRISGGGRCNFTNLYAGPQNFLSENPHFCKSALARYTPQDFISLMKRYGIAYHEKHKGQLFCDGSAEQIISMLKAECLAGGVEMLMPCKVQQLSHDGAQFKLQTDHGEMQAASVVIATGGLSIPKIGATDFAYRIAKQFDLPIIAPVPALVPLTFDAESWQAFVPLAGIALEVEIETGVKKQRGHFREDLLFTHRGLSGPAVLQISSYWKENTEIRINLLPEVELADQLIHEKSTSRKNLGNVLAQYLPSRLAEGWLQVGAYQSDQRVADMQDKTLRALGDSINNWKITPNGSEGYRKAEVTRGGIDTRALAQQTMMVNKVPGLYFIGEAVDVTGWLGGYNFQWAWASGVAAGQAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYI0</accession>
    <name>A0A2S9GYI0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2512</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92782">
        <property type="protein sequence ID" value="PRC92782"/>
        <property type="gene ID" value="S2091_2512"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="28"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="60"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="116" mass="13425" checksum="BA278E58FF187354" modified="2018-07-18" version="1">MLWIFTKYFVTAGVVMLVSEVAKRSDRLGGLLAALPLVTILTLIWLHFERQSTEKIANHAWYTFWYVVPTLPMFLVFPWLLPKIGFWSTLLVCILLSGLCFIAFAFILRRFGIELL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYM9</accession>
    <name>A0A2S9GYM9_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="12 13">DNA primase</fullName>
            <ecNumber evidence="12">2.7.7.101</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">dnaG</name>
        <name evidence="16" type="ORF">S2091_2496</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12 13">RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12 13 14">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="12 13 14">Binds 1 zinc ion per monomer.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12">Monomer. Interacts with DnaB.</text>
    </comment>
    <comment type="domain">
        <text evidence="12">Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.</text>
    </comment>
    <comment type="similarity">
        <text evidence="12 13">Belongs to the DnaG primase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.101" evidence="12"/>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92766">
        <property type="protein sequence ID" value="PRC92766"/>
        <property type="gene ID" value="S2091_2496"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990077">
        <property type="term" value="C:primosome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003896">
        <property type="term" value="F:DNA primase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03364">
        <property type="entry name" value="TOPRIM_DnaG_primases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.860.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.980.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00974">
        <property type="entry name" value="DNA_primase_DnaG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016136">
        <property type="entry name" value="DNA_helicase_N/primase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013264">
        <property type="entry name" value="DNA_primase_core_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037068">
        <property type="entry name" value="DNA_primase_core_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019475">
        <property type="entry name" value="DNA_primase_DnaB-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006295">
        <property type="entry name" value="DNA_primase_DnaG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013173">
        <property type="entry name" value="DNA_primase_DnaG_DnaB-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036977">
        <property type="entry name" value="DNA_primase_Znf_CHC2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030846">
        <property type="entry name" value="DnaG_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034151">
        <property type="entry name" value="TOPRIM_DnaG_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006171">
        <property type="entry name" value="TOPRIM_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002694">
        <property type="entry name" value="Znf_CHC2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10410">
        <property type="entry name" value="DnaB_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08278">
        <property type="entry name" value="DnaG_DnaB_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13662">
        <property type="entry name" value="Toprim_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08275">
        <property type="entry name" value="Toprim_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01807">
        <property type="entry name" value="zf-CHC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002811">
        <property type="entry name" value="DnaG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00493">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00400">
        <property type="entry name" value="ZnF_CHCC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01391">
        <property type="entry name" value="dnaG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50880">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 12 13" id="KW-0235">DNA replication</keyword>
    <keyword evidence="10 12" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1 12 13" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 12 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 12 13" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="2 12 13" id="KW-0639">Primosome</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11 12 13" id="KW-0804">Transcription</keyword>
    <keyword evidence="3 12 13" id="KW-0808">Transferase</keyword>
    <keyword evidence="8 12 13" id="KW-0862">Zinc</keyword>
    <keyword evidence="7 12 14" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Toprim" evidence="15">
        <location>
            <begin position="259"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="CHC2-type" evidence="12 14">
        <location>
            <begin position="37"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRNR" id="PIRNR002811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR002811-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="PRC92766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="597" mass="66450" checksum="D417BFD4804CAD86" modified="2018-07-18" version="1">MIPQSFIADLIARVDIVEVVGRYVQLKKGGANFMGLCPFHNEKSPSFTVSPTKQFYHCFGCGAHGTAIGFLMEYSGQGFVEAIKDLAQSHGMVVPENDQMPPLQRAEIQAKSLALSEAMTRASDYYRRQLKVAPTAIAYLQGRGLSGEIAAKFSLGYAPEGWDNLRQEFNDYDEPALAESGMVIDKEGEDGGRHKRYDRFRDRVMFPIKNTKGQVIGFGGRVMGSGEPKYLNSPETPLFQKGYELYGLFEARQAIRDAGYVLVTEGYMDVVALAQMGFPQAVATLGTACTPMHVQKLLRQTDQVIFSFDGDSAGRRAARRALDACMPLVNDSKTIKFLFLPTEHDPDSYIREYGAEVFHQIVQDAMPLSQFLLNLVSQDNDLTTLEGRAHTQFEAKPALQAMVPSSLRLQIVRGLAQLTQTTPMEIETMFELEQPVARVRVAPPRVKRNAPMGLERQMMRIILAHPPLAALMDANALLAAAELAPDGAQMLNQLVSAAQAMGKQAQFAALSDHLRNINADFDELIMEIAKQSETDAELCGLELTWAIRNMKMQQIKAEQVQLTNRGLQGESDKLRFYELKRQLDEINRQNSDEIALR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYN0</accession>
    <name>A0A2S9GYN0_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Probable nicotinate-nucleotide adenylyltransferase</fullName>
            <ecNumber evidence="7">2.7.7.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Deamido-NAD(+) diphosphorylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Deamido-NAD(+) pyrophosphorylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Nicotinate mononucleotide adenylyltransferase</fullName>
            <shortName evidence="7">NaMN adenylyltransferase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">nadD</name>
        <name evidence="9" type="ORF">S2091_2551</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 7">Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>ATP + H(+) + nicotinate beta-D-ribonucleotide = deamido-NAD(+) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:22860"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57502"/>
            <dbReference type="ChEBI" id="CHEBI:58437"/>
            <dbReference type="EC" id="2.7.7.18"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 7">Cofactor biosynthesis; NAD(+) biosynthesis; deamido-NAD(+) from nicotinate D-ribonucleotide: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 7">Belongs to the NadD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.18" evidence="7"/>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92821">
        <property type="protein sequence ID" value="PRC92821"/>
        <property type="gene ID" value="S2091_2551"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00253">
        <property type="reaction ID" value="UER00332"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004515">
        <property type="term" value="F:nicotinate-nucleotide adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009435">
        <property type="term" value="P:NAD biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02165">
        <property type="entry name" value="NMNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00244">
        <property type="entry name" value="NaMN_adenylyltr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004821">
        <property type="entry name" value="Cyt_trans-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005248">
        <property type="entry name" value="NadD/NMNAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01467">
        <property type="entry name" value="CTP_transf_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00482">
        <property type="entry name" value="TIGR00482"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 7" id="KW-0520">NAD</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 9" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="5 7" id="KW-0662">Pyridine nucleotide biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="CTP_transf_like" evidence="8">
        <location>
            <begin position="18"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC92821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="223" mass="24964" checksum="4E0962C8212B5857" modified="2018-07-18" version="1">MSEETGEAKTTNNQCIAIFGGSFDPVHSAHVALTELFNNLLKPTQLRIIPTGWSWQKTAFKTSPQQRIAMLSLAFAELSKQTSLIIDVQEIKRAELGIPSYSIDTLSILRNEFGASASLIFLMGADQLQQLQSWQNWQRLFELAHIAVVARPGFKLDAIDNLVANEFKQRAGSVEQLRNRPCGHTYLCADLAIDISSTQVRDGKNLSLLPPKVLDYIQQHHLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYQ3</accession>
    <name>A0A2S9GYQ3_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Sulfate adenylyltransferase</fullName>
            <ecNumber evidence="1">2.7.7.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_2560</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.4" evidence="1"/>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92830">
        <property type="protein sequence ID" value="PRC92830"/>
        <property type="gene ID" value="S2091_2560"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004781">
        <property type="term" value="F:sulfate adenylyltransferase (ATP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006790">
        <property type="term" value="P:sulfur compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04166">
        <property type="entry name" value="CysN_ATPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03695">
        <property type="entry name" value="CysN_NodQ_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04095">
        <property type="entry name" value="CysN_NoDQ_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041757">
        <property type="entry name" value="CysN_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044138">
        <property type="entry name" value="CysN_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044139">
        <property type="entry name" value="CysN_NoDQ_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011779">
        <property type="entry name" value="SO4_adenylTrfase_lsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009001">
        <property type="entry name" value="Transl_elong_EF1A/Init_IF2_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50465">
        <property type="entry name" value="SSF50465"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02034">
        <property type="entry name" value="CysN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3 8" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Tr-type G" evidence="7">
        <location>
            <begin position="14"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC92830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="437" mass="48138" checksum="288DCD396E0A4C5E" modified="2018-07-18" version="1">MNAAIKLQEITKERGLLRFITAGSVDDGKSTLIGRLLFDSKGIFADQLDAMSRAKHKRTVGDSIDLSLLTDGLEAEREQGITIDVAYRYFATPKRKFIIADTPGHEQYTRNMVTGASTADAVIILIDVSKVKFNDDGSVELLIQTKRHSTIAHLLQIEHVIVAVNKMDLIDFNQTKYDKIVAAYQEFANQLGLRDVTPIPLSALTGDNVVDKGDKLNWYTGPTLITLLESLSVYDASHDEPLRFPVQLVARHNGHEANDFRGYMGRIEAGKVSIGDKLIIQPSGQTGTVKDIVTLDGSLQTAVVGQSITLLLNEHLDISRGDMLAQATRPATLVSNLEADVCWLSEEPLDFKRKYLLKHTTKQVAARVTAIESLLDINTQQTHTATNLQLNDIARVKITVQQPLAADNYNEIRSTGAFILIDQVTHQTVAAGMIRLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYS3</accession>
    <name>A0A2S9GYS3_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Pantothenate synthetase</fullName>
            <shortName evidence="5">PS</shortName>
            <ecNumber evidence="5">6.3.2.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Pantoate--beta-alanine ligase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Pantoate-activating enzyme</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">panC</name>
        <name evidence="6" type="ORF">S2091_2580</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>(R)-pantoate + ATP + beta-alanine = (R)-pantothenate + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10912"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15980"/>
            <dbReference type="ChEBI" id="CHEBI:29032"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57966"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.2.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 5">Cofactor biosynthesis; (R)-pantothenate biosynthesis; (R)-pantothenate from (R)-pantoate and beta-alanine: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="5">The reaction proceeds by a bi uni uni bi ping pong mechanism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 5">Belongs to the pantothenate synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.1" evidence="5"/>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92850">
        <property type="protein sequence ID" value="PRC92850"/>
        <property type="gene ID" value="S2091_2580"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00028">
        <property type="reaction ID" value="UER00005"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004592">
        <property type="term" value="F:pantoate-beta-alanine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015940">
        <property type="term" value="P:pantothenate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00560">
        <property type="entry name" value="PanC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1300.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00158">
        <property type="entry name" value="PanC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004821">
        <property type="entry name" value="Cyt_trans-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003721">
        <property type="entry name" value="Pantoate_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042176">
        <property type="entry name" value="Pantoate_ligase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21299:SF1">
        <property type="entry name" value="PTHR21299:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02569">
        <property type="entry name" value="Pantoate_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00125">
        <property type="entry name" value="cyt_tran_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00018">
        <property type="entry name" value="panC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 6" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 5" id="KW-0566">Pantothenate biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton donor" evidence="5">
        <location>
            <position position="33"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="26"/>
            <end position="33"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="57"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="144"/>
            <end position="147"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="150"/>
        </location>
        <ligand>
            <name>(R)-pantoate</name>
            <dbReference type="ChEBI" id="CHEBI:15980"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="181"/>
            <end position="184"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009256"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC92850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="279" mass="31568" checksum="59F5FEA3A6400D96" modified="2018-07-18" version="1">MKIVTSIEELRDQLRGQLRTAFVPTMGNLHEGHLSLMRLAKRHGDPVVASIFVNRLQFGPNEDFDKYPRTFQADVEKLEKEGVYVLFAPTEKDLYPEPQEYRVQPPEGLGNILEGEFRPGFFTGVSTIVLKLFSCVQPRVAVFGKKDYQQLMIVRNMSKQFALPTEIIAAETYRAEDGLALSSRNMYLSETERAEAPELYKALNQVAEEVRSGHLDMFQLEKAAMAQLAQRHWKPDYISIRKRCDLQPPSAGDLATKEPLVVVAAAKLGTTRLIDNLEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZ91</accession>
    <name>A0A2S9GZ91_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Sulfatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_2138</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93052">
        <property type="protein sequence ID" value="PRC93052"/>
        <property type="gene ID" value="S2091_2138"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008484">
        <property type="term" value="F:sulfuric ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016772">
        <property type="term" value="F:transferase activity, transferring phosphorus-containing groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040423">
        <property type="entry name" value="PEA_transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30443">
        <property type="entry name" value="PTHR30443"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="43"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="75"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="118"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="157"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="domain" description="Sulfatase" evidence="7">
        <location>
            <begin position="233"/>
            <end position="517"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC93052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="551" mass="59938" checksum="9AA928383882749B" modified="2018-07-18" version="1">MFKFKTLKNNGAIARILFWLVLFLPTILALWRSHGNGRTWQTLLWAAAACLFPAILPPVLFIAVQWLCLLLLPVLLWWIAYAALNGIGPGWEAAVAAISTSPQEASGAALLAINTPNFLLFAVACSLLLIASIVLMFRARKSHVLNDASQECRKVLFVLALAPFFISFMTNATGVHLPVLFIASDPSFSTLGTTTRLLWEGVDQIMYGDIMTVAPERRKAVAPRMAKDVRLAIFVIGESMRAGGIGPAQKQRGPWTKALNERVENHLGVWLPTTCAGANGTAGSVPMLLTGLAPRQYAESGTAPSVLAVLKAAGYKTAWISNQDKSVFTEHGHDYYWTITHSASVSDSYDEQLVPIAKTFAAPILNHGTQSRIPYAMALHMHGSHFDYQDRYPVSQFAAEPTGLSYEDLVDLRYERTEEYTAKVINDLAALLDASEAPSFLIYSSDHGENLPSDHNGVTTHLGPRATLRDGTTTSFVLWNSAMQKTGKPTEILSQLMKEPMIAHADVAKIFLALAGVGDEAIVTNLPPEILAPVELGGSYNKPNACSLLKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZA7</accession>
    <name>A0A2S9GZA7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2155</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93069">
        <property type="protein sequence ID" value="PRC93069"/>
        <property type="gene ID" value="S2091_2155"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="74" mass="8237" checksum="747B110928DBE22C" modified="2018-07-18" version="1">MKKLYPSEFIQIRRSLLERTIAEIRANYPNNELSDNQKNSNARDFVACAVGLLANSEPEISSTLAAVIGMKPLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZE6</accession>
    <name>A0A2S9GZE6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative phage tail protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_2187</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93101">
        <property type="protein sequence ID" value="PRC93101"/>
        <property type="gene ID" value="S2091_2187"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00063">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015406">
        <property type="entry name" value="DUF1983"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003961">
        <property type="entry name" value="FN3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032876">
        <property type="entry name" value="J_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09327">
        <property type="entry name" value="DUF1983"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13550">
        <property type="entry name" value="Phage-tail_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phage-tail_3" evidence="3">
        <location>
            <begin position="341"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1983" evidence="2">
        <location>
            <begin position="980"/>
            <end position="1043"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09327"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC93101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="1500" mass="160890" checksum="9409201B95C41B68" modified="2018-07-18" version="1">MSEIIGYGGKGGGGGSGSKETRDSLRSISYAKVLDLVSEGEIQGLVNGLQSIFFDGTRLQNQDGTFNFRDVTADFRPGTQNQDVIAGFPGVENEITIGHELRSEAPWVRAINNTQLSAVRLRLAVAALSKMDKENGDVNGYKIAYQIDVATDGGGYKPVINQTFDGKTTSRYERSHRIELPPAKTGWVIRITRATPNANSALIADTTLISTLTEVIDVKLRYPMSAIVGIQIDASQFQGIPTRSYDLRGRIIKVPSNYDPISHVYTGVWDGTFKPAWTNNPAWVFYDLVLNDRYGLGHTLDASTIDKWSLYQIGRYCDVKVPDGLGGTEPRFTCNLYLQTAAEAYKVLQDLASLFRGISYWAAGSIITSADIPTDPTYIYTAANVIDGKFTGVGSSQRTRYTVALVSWNDPADFYKARVEYVQDDDGIARYGVQKISMTAFGCTSQGQAQRAGNWALLTSRLETDTLTFSVGLDGLVSSPGQIVRIADPHRMGRRNAGRLRHAVGRTVTLDKAPVIAVGDDFTVILPTGITETRKVMAISGDTVTVQRDWSTLPVAQAIWSVDNIDLIAPSYKILSIIEKGGLTYEITALQHEPGKFEYIDNGTRIEERPHTGLESAPSTPTNLLFTSHPYWVDDSVVATNATLSWTGFSPVYRVLWRKALGTWADIKTRSPSIDFKSVEASEYEFKVSAISSTGLESPPAIFNATVTPTLPPLDDITGLRLESGFTTNSAKIAWDNVKGATSYRAQVVVGKPAIVVRTINVGDTPRFEYTVGDMKVDGGPWRTVEFRIKALGKFGTGSAVASLIATNKQIGALVNIRVDQGIRAGYFNCTPPPEDDFAGIIIWISTDPACPALPENEIYDGADSFVTLTKFTDGEALDKKNEYYIRAAAYDSLGKDDLNVSTAIPLTVAGVLPDVGSILESMLTKELSDKITAIGEFDPNDIVAQIVKEEEARKDAVGAVATTVLTVQTQLNGNIASVQAQAKSIDGLSAQYTVKTDVNGYVAGYGLATTIVEGIPQSDFTILADRFAVVQPGVQKRVPFVVTSKNGVAQIGIDGNLLVNGSVTADSILANAITGDKIKAGSLSANVFESGVGSGNLLYNASLTATYETGGLILPDGYIGGTDFYINPFTFSINGAGDAWRPVGVNVISVNQRGVAPNDNQYVLSPAVSIVQGAYYEMSIYTGAHRCHISIAIGWVDVNGAWAGFTHGGWINAEEAYGGTTLSGYKRLFILGQAPAGAVAGRLITYKNGTLYGGDSWMFLCMPYIGVANGANQTLPSPWSPPGIGTQIHGGAIKTSTITADRLAVSDLSAISANLGRITAGDLYSTTIHGGSGYPTSNYAWPNNGGNGFHLSSSGLLLGNAHNGRYFQATANGDLYAPGMSIINGKLTINELKVINTDQLEDNSVTEIETAVSASGAEVVVNVSAGNVSRNGTTPIVFMMHSANPTRRLTVYKDGKSIFSSESIVSVFYAPPGRYVCRVSHAGEMTGRQTSLVAIKVKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZF1</accession>
    <name>A0A2S9GZF1_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Elongation factor P</fullName>
            <shortName evidence="7">EF-P</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">efp</name>
        <name evidence="10" type="ORF">S2091_2201</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Protein biosynthesis; polypeptide chain elongation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the elongation factor P family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93115">
        <property type="protein sequence ID" value="PRC93115"/>
        <property type="gene ID" value="S2091_2201"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00345"/>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04470">
        <property type="entry name" value="S1_EF-P_repeat_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05794">
        <property type="entry name" value="S1_EF-P_repeat_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00141">
        <property type="entry name" value="EF_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015365">
        <property type="entry name" value="Elong-fact-P_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_L2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020599">
        <property type="entry name" value="Transl_elong_fac_P/YeiP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013185">
        <property type="entry name" value="Transl_elong_KOW-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001059">
        <property type="entry name" value="Transl_elong_P/YeiP_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011768">
        <property type="entry name" value="Transl_elongation_fac_P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30053">
        <property type="entry name" value="PTHR30053"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01132">
        <property type="entry name" value="EFP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08207">
        <property type="entry name" value="EFP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09285">
        <property type="entry name" value="Elong-fact-P_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005901">
        <property type="entry name" value="EF-P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01185">
        <property type="entry name" value="EFP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00841">
        <property type="entry name" value="Elong-fact-P_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="SSF50104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 7 10" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="6 7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EFP" evidence="9">
        <location>
            <begin position="67"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="Elong-fact-P_C" evidence="8">
        <location>
            <begin position="128"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC93115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="188" mass="21147" checksum="EBFCFFDD85739FC2" modified="2018-07-18" version="1">MKPAKEIKVGNIIMVDGNPMIVLRIDINGSSRTGFTFKWKMKNLLTGSPLENVFKGSESFDVIVLDKKEVTYSYFADPLFVFMDTDYNQYEIEGENLGDALNYLKDGMECEAVFYDGKAISVELPTTIVRQVVYSEPAVKGNTSGNVLKEAKIENATGNLFTVQVPLFVAQDDMIEIDTRTNEYKKRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZP8</accession>
    <name>A0A2S9GZP8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glutamine synthetase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1947</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glutamine synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93209">
        <property type="protein sequence ID" value="PRC93209"/>
        <property type="gene ID" value="S2091_1947"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004356">
        <property type="term" value="F:glutamate-ammonia ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006542">
        <property type="term" value="P:glutamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036651">
        <property type="entry name" value="Gln_synt_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014746">
        <property type="entry name" value="Gln_synth/guanido_kin_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008146">
        <property type="entry name" value="Gln_synth_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027303">
        <property type="entry name" value="Gln_synth_gly_rich_site"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00120">
        <property type="entry name" value="Gln-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01230">
        <property type="entry name" value="Gln-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54368">
        <property type="entry name" value="SSF54368"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55931">
        <property type="entry name" value="SSF55931"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00181">
        <property type="entry name" value="GLNA_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gln-synt_C" evidence="2">
        <location>
            <begin position="119"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="456" mass="51673" checksum="D988E5B8E07D3367" modified="2018-07-18" version="1">MSLRQNFSYNDMDQWLNEKRVTEIECLVPDLTGVARGKIMPRTKFTEDRGMRMPEAVLGMTVTGNYPTDNAAYERAISAIDRDMILRADPNTITMVPWAADPTAQVIHDCYFSDGSLVDFAPRSVLRRVLSLYAEKGWTPIVAPELEFYLTAKNIDPDIPLRPPVGRSGRAETSRQIYSIDAVNEFDPLFEDIYDYCELMQLDVDTLIHEIGAGQMEINFLHGEPMGLADKVFFFKRTLREAALKHDMYATFMAKPMTGEPGSAMHIHQSVVDTKTGLNIFSNQDGSSSEAFMHYIGGLQRYMPAAMAIVAPYVNSYRRIVRHTAAPINIQWGKDNRTVGFRVPESGPQDRRVENRVVGADANPYLALAVTLACGYLGMIEKLEPTPITVDSAYDLDYQLPQSLSEALEGLRKETRLRYILGDRFIDVYSAIKELEHREFMQVISPWEREHLLLHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZU3</accession>
    <name>A0A2S9GZU3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative MetA-pathway of phenol degradation</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1958</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93220">
        <property type="protein sequence ID" value="PRC93220"/>
        <property type="gene ID" value="S2091_1958"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015771921" evidence="1">
        <location>
            <begin position="29"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="260" mass="28445" checksum="FAFDD25D9C6B5470" modified="2018-07-18" version="1">MKNSALSKLFSCTARLIVLLSFPLSAFAIGGPPLVTDDPDTPGDGHWEINLATISQRTAYGYAVAAPDADINYGVGEHIQLKADIPWTFAQQPGEGWKSGPGFANYGVKWRFIDEEDAGFSVSTYPQYEHSLSSSSITRGIAPSGGQFFLPLEVSTKMNEFDLDMEVGRNFVQGNPNQWEAGFVIGHECVKDVECLAEIHETLTDRFSGNASSTQTLLNLGLNWKLTESMTLLAAAGREFGKQSNSQIYSLFYLGIQITR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZW1</accession>
    <name>A0A2S9GZW1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_2013</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 4">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the trans-sulfuration enzymes family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93275">
        <property type="protein sequence ID" value="PRC93275"/>
        <property type="gene ID" value="S2091_2013"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016765">
        <property type="term" value="F:transferase activity, transferring alkyl or aryl (other than methyl) groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019346">
        <property type="term" value="P:transsulfuration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00614">
        <property type="entry name" value="CGS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000277">
        <property type="entry name" value="Cys/Met-Metab_PyrdxlP-dep_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006235">
        <property type="entry name" value="OAc-hSer/O-AcSer_sulfhydrylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01053">
        <property type="entry name" value="Cys_Met_Meta_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001434">
        <property type="entry name" value="CGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01326">
        <property type="entry name" value="OAH_OAS_sulfhy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00868">
        <property type="entry name" value="CYS_MET_METAB_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="3">
        <location>
            <position position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR001434-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU362118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC93275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="434" mass="46643" checksum="EBD6E704F527F7C2" modified="2018-07-18" version="1">MLSAIRHGEAVMKLETIAVHGGYSPDPTTKAAAVPIYQTSSYAFDSTQHGADLFDLKVAGNIYTRIMNPTQDVLEKRVAELEGGIGALALASGQAAITYAIQTIAEAGDNIVSATTLYGGTYNLLAHTLPQFGITTRFADHREPASFERLIDTKTKAIFVEAIGNPLGNITDIEAIAAIAHKHGIPLIVDNTVPSPYLLRPFEFGSDIVVHSLTKYLGGHGNSLGGIIVDSGKFPWADHKEKFPRLNEPDVSYHGVVYTEALGAAAYIGRARVVPLRNMGAAISPFNAFLILQGIETLALRMDRITDNTIKIAKYLQAHKKVKWVNYAGLPEHRDHALAQKYLGGRPSGILTFGVEGGLAGGGRFQDALQLFTRLVNIGDAKSLACHPASTTHRQLSPQELIKAGVTEDTVRLSIGIEHVDDLIADLEQALAAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZW3</accession>
    <name>A0A2S9GZW3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1976</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93238">
        <property type="protein sequence ID" value="PRC93238"/>
        <property type="gene ID" value="S2091_1976"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021607">
        <property type="entry name" value="DUF3224"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023159">
        <property type="entry name" value="SO1590-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11528">
        <property type="entry name" value="DUF3224"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF159238">
        <property type="entry name" value="SSF159238"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="135" mass="14493" checksum="BE257F473C2467C6" modified="2018-07-18" version="1">MMSMQATGTFEVKLMPESLSGIAEKTGLGRMLLDKKFQGDLEASSQGEMLAFRSSVPSSAGYVAMETVSGTLHGRSGSFVLQHSSTMTRGVSEQSITVVPDSGTEDLAGLVGRLVIIIVESQHRYQFDYTLPENA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZX7</accession>
    <name>A0A2S9GZX7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1991</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93253">
        <property type="protein sequence ID" value="PRC93253"/>
        <property type="gene ID" value="S2091_1991"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2280">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031560">
        <property type="entry name" value="CzcE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038674">
        <property type="entry name" value="CzcE_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16986">
        <property type="entry name" value="CzcE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015505654" evidence="1">
        <location>
            <begin position="21"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="112" mass="12602" checksum="C5890FA77DEF4947" modified="2018-07-18" version="1">MKRKLLLMTMLAVVFLPACMTPMDLTKKISFWGDPASISFADRTIIIYQNTSYVNVTGGEIIKFIVGNKSFSWHFNGAGQYNFDLMLVAPQGMLDHRVMAYVESDPRFAGGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H014</accession>
    <name>A0A2S9H014_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phosphoglycerate dehydrogenase and related dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2067</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93329">
        <property type="protein sequence ID" value="PRC93329"/>
        <property type="gene ID" value="S2091_2067"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029753">
        <property type="entry name" value="D-isomer_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006140">
        <property type="entry name" value="D-isomer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02826">
        <property type="entry name" value="2-Hacid_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00671">
        <property type="entry name" value="D_2_HYDROXYACID_DH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2-Hacid_dh_C" evidence="2">
        <location>
            <begin position="124"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="330" mass="36433" checksum="F89024C01CE8E95B" modified="2018-07-18" version="1">MQLDLRLREDDGIEGFTLNKNMNIIYCNQSSNPEVPLRAFQNALPHAKIRQWQAGDNAPADYALVWKPPVEMLAGRDDLKAIFNLGAGVDAIIKMVDQLPKQVPIIRLEDAGMGEQMADYVCHAVLHYFRRFDLFARQAQHAHWQSIAPLSKKEFTVGVLGMGTLGQSIAASLLQLKFPVIGWSNSAKQIDEIQCYSGADELPKFLAESKVIVCILPLTEQTSGILNRHTLAQLPRGAYVINVARGAHIVEQDLLELVRNGHIAGATLDVVQTEPLPGNHPFWQEPKITITPHVAALTLWDESAVQIAEKIALLEQGLPVTGVIDCVKGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0B4</accession>
    <name>A0A2S9H0B4_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Alpha-galactosidase</fullName>
            <ecNumber evidence="5">3.2.1.22</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Melibiase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_1785</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>Hydrolysis of terminal, non-reducing alpha-D-galactose residues in alpha-D-galactosides, including galactose oligosaccharides, galactomannans and galactolipids.</text>
            <dbReference type="EC" id="3.2.1.22"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the glycosyl hydrolase 27 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.22" evidence="5"/>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93398">
        <property type="protein sequence ID" value="PRC93398"/>
        <property type="gene ID" value="S2091_1785"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052692">
        <property type="term" value="F:raffinose alpha-galactosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14792">
        <property type="entry name" value="GH27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002241">
        <property type="entry name" value="Glyco_hydro_27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000111">
        <property type="entry name" value="Glyco_hydro_27/36_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041233">
        <property type="entry name" value="Melibiase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11452">
        <property type="entry name" value="PTHR11452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16499">
        <property type="entry name" value="Melibiase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17801">
        <property type="entry name" value="Melibiase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00740">
        <property type="entry name" value="GLHYDRLASE27"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00512">
        <property type="entry name" value="ALPHA_GALACTOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4 5" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Melibiase_C" evidence="6">
        <location>
            <begin position="327"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU361168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF17801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC93398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="409" mass="45774" checksum="ED1BE20ECCD2182F" modified="2018-07-18" version="1">MKPFRILILLILIVSQLLVIQYARAEAAPPRPERVGNNLALTPPMGWNTWNKFACNVSEALLRQAADAMVTSGMRDAGYEYIVIDDCWQQGRDKAGNIYADPARFPSGMKALGDYIHSRGLKFGIYSDAGSLTCGKRPGSLGHEYQDAQKYAEWGVDYLKYDWCSTYDQNAKSSYETMSDALRATGRPIVLSICEWGLNKPWQWGTNIGNLWRTTDDIYDHWEGKKTFEHGVMDILDLQVGLESFSGPGHWNDPDMLEVGNGKMSNEEYRSHFSLWAILAAPLMAGNDLSAMTEQTRAILTNREVIAIDQDALGIQAKRVAKHVGDEVWARPLQGGGRAVVLLNRSETAHSVTVSWDMLNLPDQLDMQLRDVWLAKNLPAARSSYTAMVPSHGVVMLRLDYRPMQGAEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0H3</accession>
    <name>A0A2S9H0H3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cbb3-type cytochrome oxidase component FixQ</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1866</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93479">
        <property type="protein sequence ID" value="PRC93479"/>
        <property type="gene ID" value="S2091_1866"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008621">
        <property type="entry name" value="Cbb3-typ_cyt_oxidase_comp"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05545">
        <property type="entry name" value="FixQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="63" mass="7160" checksum="6ED93BE0C0B0ADBE" modified="2018-07-18" version="1">MAIDLIFNNASVVMTVVSLITFLGILWWIFGYKRSSDFDAIANLPFVEDADDAQELNVEKRHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0K0</accession>
    <name>A0A2S9H0K0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Biopolymer transport protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_1773</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the ExbD/TolR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93386">
        <property type="protein sequence ID" value="PRC93386"/>
        <property type="gene ID" value="S2091_1773"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003400">
        <property type="entry name" value="ExbD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30558">
        <property type="entry name" value="PTHR30558"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02472">
        <property type="entry name" value="ExbD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC93386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="142" mass="15364" checksum="C4FD970D6D2E1898" modified="2018-07-18" version="1">MGMNISSGSSSEPDVMIEMNMTPLIDVMLVLIIMLIITIPIQNHAVNLNMPNGTPPPQVAPPTVVNIDIDFDGTILWDGNVIPDHASLEEHMRAVAAIPDQPEMHLRPNKLVAYKTVASVMAAAQRLGVTKIGMVGNEQFVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0K4</accession>
    <name>A0A2S9H0K4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1899</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93512">
        <property type="protein sequence ID" value="PRC93512"/>
        <property type="gene ID" value="S2091_1899"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="96" mass="10708" checksum="681BEDC542B0954F" modified="2018-07-18" version="1">MRKPATVSRNHVVHLARSGSNEGSHNFSKVKLTYINLPLTNDHFRFGIIDKAPGHQGDGCQTPGTTFFALLRGQQSAEGRPCHFLLRLANRLQLTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0R6</accession>
    <name>A0A2S9H0R6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1558</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93557">
        <property type="protein sequence ID" value="PRC93557"/>
        <property type="gene ID" value="S2091_1558"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="90" mass="10566" checksum="284175856E4D8425" modified="2018-07-18" version="1">MFQLLCHGSFLFFKCRDCVKTKNKFEREKIDLLKRSLFNYFNVGNGFPTHAFSEKACNFLFLHIDGRPHFAKLLFTDVKKVEIAAIDPDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0T3</accession>
    <name>A0A2S9H0T3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1595</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93594">
        <property type="protein sequence ID" value="PRC93594"/>
        <property type="gene ID" value="S2091_1595"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015783574" evidence="1">
        <location>
            <begin position="20"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="328" mass="36725" checksum="B18E16ED25800A10" modified="2018-07-18" version="1">MKNLLAALLSLLVFNSASAATTDETTSSFSAPAHRVTFEFHSAFLMNLHHVLVDAAVHDGKLETLPWQEKPSAAEWQTLQNAVTFYRDNYAKRSLLFDKTMTDIKVALSVDDTRRDATGLNLPPDLIAVLNSVAPIYARGLWSIQDRSNQLWIQQAKSLDALYGAEVQAGIEHYLQHGFPLTPVRDDVVVETGDRRGAYTDEQTVLPSGRADYSGLATLEMLYHEASHINVTDTLSDAIDARLKATDRSDKFQLWHAVQFYTVGKVVQDVYKQRANLDYRPYADKNGVYQRGWSIFVPSLNDIWLPYMNGKSTLQEAVTAMVDKLPAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H122</accession>
    <name>A0A2S9H122_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative addiction module antidote protein, CC2985 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1680</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93679">
        <property type="protein sequence ID" value="PRC93679"/>
        <property type="gene ID" value="S2091_1680"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.10.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022789">
        <property type="entry name" value="ParD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038296">
        <property type="entry name" value="ParD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010985">
        <property type="entry name" value="Ribbon_hlx_hlx"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36582">
        <property type="entry name" value="PTHR36582"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03693">
        <property type="entry name" value="ParD_antitoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47598">
        <property type="entry name" value="SSF47598"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02606">
        <property type="entry name" value="antidote_CC2985"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-1277">Toxin-antitoxin system</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="81" mass="9238" checksum="BAFAE8CBB87D56AA" modified="2018-07-18" version="1">MGTVRKTITLTDQQDNWIKAQIDAGHYTNDSEYIRDLIRREQERNTEIEVIRAALIAGESSGEPKSFNADVFKQKMLTSHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1C9</accession>
    <name>A0A2S9H1C9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1403</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93794">
        <property type="protein sequence ID" value="PRC93794"/>
        <property type="gene ID" value="S2091_1403"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00211">
        <property type="entry name" value="PTS_IIA_fru"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016152">
        <property type="entry name" value="PTrfase/Anion_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002178">
        <property type="entry name" value="PTS_EIIA_type-2_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00359">
        <property type="entry name" value="PTS_EIIA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55804">
        <property type="entry name" value="SSF55804"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51094">
        <property type="entry name" value="PTS_EIIA_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00372">
        <property type="entry name" value="PTS_EIIA_TYPE_2_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PTS EIIA type-2" evidence="1">
        <location>
            <begin position="6"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="155" mass="16953" checksum="4BC998A6D9DACD04" modified="2018-07-18" version="1">MTNIAKILPLPNVILNLEVSSKKRAFEQAGLLFENNCGIARSIVSENLFARERLGSTGLGHGVAIPHGRIKGLKKPVAAFIRLAEPIPFESPDSEPVHLLIFLLMPDSVTKQHLAILAEIAEMFSDTTIRAELSNATDAVAVHNRILEWQPQITA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1E4</accession>
    <name>A0A2S9H1E4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative addiction module antidote protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1411</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93802">
        <property type="protein sequence ID" value="PRC93802"/>
        <property type="gene ID" value="S2091_1411"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014057">
        <property type="entry name" value="HI1420"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40275">
        <property type="entry name" value="PTHR40275"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02684">
        <property type="entry name" value="dnstrm_HI1420"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="101" mass="10694" checksum="9AFD7AC79E87924F" modified="2018-07-18" version="1">MKKHIVVANLPEFDAASYLDSEASIAAYLTDILQANDAALLAAALGDIARARGMTEIAKSAGITREALYKALRPDSAPRFDTISRVCAALGVRLVAQPIHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1N7</accession>
    <name>A0A2S9H1N7_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Flagellar biosynthesis protein FlhA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">flhA</name>
        <name evidence="8" type="ORF">S2091_1510</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93901">
        <property type="protein sequence ID" value="PRC93901"/>
        <property type="gene ID" value="S2091_1510"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044780">
        <property type="term" value="P:bacterial-type flagellum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.540">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042194">
        <property type="entry name" value="FHIPEP_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042193">
        <property type="entry name" value="FHIPEP_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042196">
        <property type="entry name" value="FHIPEP_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006301">
        <property type="entry name" value="FlhA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001712">
        <property type="entry name" value="T3SS_FHIPEP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30161">
        <property type="entry name" value="PTHR30161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00771">
        <property type="entry name" value="FHIPEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005419">
        <property type="entry name" value="FlhA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00949">
        <property type="entry name" value="TYPE3IMAPROT"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01398">
        <property type="entry name" value="FlhA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1005">Bacterial flagellum biogenesis</keyword>
    <keyword evidence="7" id="KW-1006">Bacterial flagellum protein export</keyword>
    <keyword evidence="3 7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0966">Cell projection</keyword>
    <keyword evidence="8" id="KW-0969">Cilium</keyword>
    <keyword evidence="8" id="KW-0282">Flagellum</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="38"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="70"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="101"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="196"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="238"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="280"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU364093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC93901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="679" mass="74352" checksum="B834530FAA8E2ECB" modified="2018-07-18" version="1">MNALRKILGANTDIFMVLLIVGVLLVLFTPIPPALLDLLILANFSFALLILLLTFYMAKPVEFSTFPSMLLIATLFRLSLNVAATRLILRDADAGHVIGAIGSYVVGGNYVIGLIVFFILIVVQYVVVTSGAQRVSEVAARFTLDSMPGQQMSIDADLNMGFIDQQEAQRRRKNISKEAAFYGAMDGASKFVKGDAIAGIIIMMINIIGGLIIGVMQLGMGWTQALQSYTLLTIGDGIVTQVPALIISVGTGLIVTRSASDDNLSLAAFRQMTSHPRTILLVALALFGLTALPGIPAIPAMVLVGAYLLVFVLKRGAKAAKENIEQESTDADVVEQDTYSMLNIEPIEVTFGTNLVPLLEGDEALFMERIASFRKQYALESGLILPSIRFRNGAKLGPNEYEIMIFGVNVARGELLLDHTLAIHSGGDQKKLRGTETKEPTYGLPAVWIDAAEREVARAAKFTLVDPPTVFMTHLSEVLRRQSANLLTRKELERLLGRVRTQQPGLVEEIIPTSLSISDVQRVLQNLLKEKVSIRNLDAIVETLADRVRTSKDPMQLTEMVRQRLASVICQSLVGNNAYLQVMTLDPIIEQRLLQGIRDIESGGAFAIEPKFAEQFVARLAQQADKMMKSNAIPVLICAPDLRRHIRTLSERMAPHLRVLSLAEIPTNIELRAFGAVTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1N8</accession>
    <name>A0A2S9H1N8_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Flagellar L-ring protein</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Basal body L-ring protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">flgH</name>
        <name evidence="7" type="ORF">S2091_1514</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 5">Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell outer membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Bacterial flagellum basal body</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the FlgH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93905">
        <property type="protein sequence ID" value="PRC93905"/>
        <property type="gene ID" value="S2091_1514"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009427">
        <property type="term" value="C:bacterial-type flagellum basal body, distal rod, L ring"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003774">
        <property type="term" value="F:cytoskeletal motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071973">
        <property type="term" value="P:bacterial-type flagellum-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00415">
        <property type="entry name" value="FlgH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000527">
        <property type="entry name" value="Flag_Lring"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34933">
        <property type="entry name" value="PTHR34933"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02107">
        <property type="entry name" value="FlgH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01008">
        <property type="entry name" value="FLGLRINGFLGH"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0975">Bacterial flagellum</keyword>
    <keyword evidence="5" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="7" id="KW-0966">Cell projection</keyword>
    <keyword evidence="7" id="KW-0969">Cilium</keyword>
    <keyword evidence="7" id="KW-0282">Flagellum</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015411842" description="Flagellar L-ring protein" evidence="6">
        <location>
            <begin position="22"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC93905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="190" mass="20353" checksum="20D7175953BF2545" modified="2018-07-18" version="1">MKKSMLCATALIVSFASQIQAEDLYKEQTYRPLAADKRAHLPGDSVTVMIYENSSASSSANTNVTRSSNLGVQAAATQVNHQASLGTSSNFDGGGTVQRSDNLLAQITVTVEKIAPNGDLWVSGEQVVEINSDKQHIKVEGRIRTLDISDTNTVPSNRIAEAKISYLGDGDLASHQKPGLITSFFAWIGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1N9</accession>
    <name>A0A2S9H1N9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Flagella basal body P-ring formation protein FlgA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_1513</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93904">
        <property type="protein sequence ID" value="PRC93904"/>
        <property type="gene ID" value="S2091_1513"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044780">
        <property type="term" value="P:bacterial-type flagellum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017585">
        <property type="entry name" value="Flag_basal_body_FlgA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039246">
        <property type="entry name" value="Flagellar_FlgA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013974">
        <property type="entry name" value="SAF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36307">
        <property type="entry name" value="PTHR36307"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13144">
        <property type="entry name" value="ChapFlgA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00858">
        <property type="entry name" value="SAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03170">
        <property type="entry name" value="flgA_cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0966">Cell projection</keyword>
    <keyword evidence="6" id="KW-0969">Cilium</keyword>
    <keyword evidence="6" id="KW-0282">Flagellum</keyword>
    <keyword evidence="3" id="KW-0574">Periplasm</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015500074" evidence="4">
        <location>
            <begin position="22"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="domain" description="SAF" evidence="5">
        <location>
            <begin position="196"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC93904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="322" mass="34314" checksum="BEF0C551FFD77226" modified="2018-07-18" version="1">MKTVCTFLTLLLISVSVCCHAQQTGAVHAVLQAEVLVDGRVITLGDVARLSGASPAALDTLRGVQLATAPQPGYSSHLTQREVLRLLHEAGIQELVVEGADATTVMTVAIPFDPEPLVAVAKTSLAGSLRRDGLSLELTHSETLPVIRLPRGEVTLRPRQASVDRPRSHMVAWVDILLDGSFYRSVPVSFSVSALQQVLVTRSSLNKGQVLSCDNVELEQRDIAQLAANPQVGDCSNLKRRLRRNLSTGEVLLSGELEAIPAVSEGDIVTLEVTKGAVVLESHALALTDGQVGQRISVRATLSQEPVLAMVIAPGIVNVSER</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1P6</accession>
    <name>A0A2S9H1P6_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 10">Flagellar biosynthetic protein FliR</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">S2091_1508</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 10">Role in flagellar biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cell membrane</location>
            <topology evidence="10">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Bacterial flagellum basal body</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the FliR/MopE/SpaR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93899">
        <property type="protein sequence ID" value="PRC93899"/>
        <property type="gene ID" value="S2091_1508"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009425">
        <property type="term" value="C:bacterial-type flagellum basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044780">
        <property type="term" value="P:bacterial-type flagellum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006605">
        <property type="term" value="P:protein targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006303">
        <property type="entry name" value="FliR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002010">
        <property type="entry name" value="T3SS_IM_R"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30065">
        <property type="entry name" value="PTHR30065"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01311">
        <property type="entry name" value="Bac_export_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00953">
        <property type="entry name" value="TYPE3IMRPROT"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01400">
        <property type="entry name" value="fliR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0975">Bacterial flagellum</keyword>
    <keyword evidence="5 10" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="11" id="KW-0966">Cell projection</keyword>
    <keyword evidence="11" id="KW-0969">Cilium</keyword>
    <keyword evidence="11" id="KW-0282">Flagellum</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="39"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="79"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="124"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="178"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="213"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU362071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC93899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="255" mass="27327" checksum="C57F65CD195E4A45" modified="2018-07-18" version="1">MPLEIDVGMAWITSVLLCSLRLSAMLMMTPILDGFGIPARIRIFLVIALSAALVSALPHNSAAETFAAGPFFASAASELFTGALLGFGAMCAFAAFSFAGNLLDQQLGFGLANVFDPMTRAQSPLIASLFGLMAVVMFFTVDAHHALLRGFAYSLEKVPLGSAMHIVSPGLLVHQFGLIFSFGLLLAAPVLFCVYLIEIGMAVISRNLPQMNIFMISIPVKIICGLILLSILMTRLAPLFNKIFGSIFSFWEGVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1Q8</accession>
    <name>A0A2S9H1Q8_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Flagellar hook-basal body complex protein FliE</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">fliE</name>
        <name evidence="4" type="ORF">S2091_1518</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 3">Bacterial flagellum basal body</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the FliE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93909">
        <property type="protein sequence ID" value="PRC93909"/>
        <property type="gene ID" value="S2091_1518"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009425">
        <property type="term" value="C:bacterial-type flagellum basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003774">
        <property type="term" value="F:cytoskeletal motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071973">
        <property type="term" value="P:bacterial-type flagellum-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00724">
        <property type="entry name" value="FliE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001624">
        <property type="entry name" value="FliE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34653">
        <property type="entry name" value="PTHR34653"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02049">
        <property type="entry name" value="FliE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01006">
        <property type="entry name" value="FLGHOOKFLIE"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00205">
        <property type="entry name" value="fliE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0975">Bacterial flagellum</keyword>
    <keyword evidence="4" id="KW-0966">Cell projection</keyword>
    <keyword evidence="4" id="KW-0969">Cilium</keyword>
    <keyword evidence="4" id="KW-0282">Flagellum</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC93909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="102" mass="11042" checksum="469A47407E4F3C5C" modified="2018-07-18" version="1">MTIDAISFLPATSLPSLLPAGESNSTLTTGGAFGAWFEQHLSEINSKMAIADTGVQQLAAGDATNLHEVMINLQEARMSLQLMMQVRNHLLDAYHDVAQMQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1U7</accession>
    <name>A0A2S9H1U7_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Transport permease protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_1138</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell inner membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the ABC-2 integral membrane protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC93965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93965">
        <property type="protein sequence ID" value="PRC93965"/>
        <property type="gene ID" value="S2091_1138"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC_2_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000412">
        <property type="entry name" value="ABC_2_transport"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51012">
        <property type="entry name" value="ABC_TM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="40"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="72"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="122"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="152"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="188"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="244"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="domain" description="ABC2_membrane" evidence="7">
        <location>
            <begin position="28"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC93965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="273" mass="30803" checksum="105536106FAF1FDD" modified="2018-07-18" version="1">MLQIQILARIKNSLLALWHFRGFILGSVQREFQARYRNSMLGAAWMVLNPLSMIFVYTVIFTKLMHPRLPSAGSQFSYGIYLCAGLLTWGLFTDSVSRLQNVFIENGNLIKKQSFPRSCLPIISIMNALINFTIIFGLFLIFLLITGNFPGWVFLGLIPVLLIQILFSIGLGVILGVLNVFFRDVGQLFGIVLQFWFWFTPIVYTASILPEEVQPLLKLNPMASLIIAYQGIFVSGVWPQWSSLWPATLISGVLCLCGMALFRKHVGEMADEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1W8</accession>
    <name>A0A2S9H1W8_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Anthranilate phosphoribosyltransferase</fullName>
            <ecNumber evidence="4">2.4.2.18</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">trpD</name>
        <name evidence="7" type="ORF">S2091_1116</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>diphosphate + N-(5-phospho-beta-D-ribosyl)anthranilate = 5-phospho-alpha-D-ribose 1-diphosphate + anthranilate</text>
            <dbReference type="Rhea" id="RHEA:11768"/>
            <dbReference type="ChEBI" id="CHEBI:16567"/>
            <dbReference type="ChEBI" id="CHEBI:18277"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="EC" id="2.4.2.18"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="4">Binds 2 magnesium ions per monomer.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 2/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the anthranilate phosphoribosyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.18" evidence="4"/>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC93943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93943">
        <property type="protein sequence ID" value="PRC93943"/>
        <property type="gene ID" value="S2091_1116"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00035">
        <property type="reaction ID" value="UER00041"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004048">
        <property type="term" value="F:anthranilate phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000162">
        <property type="term" value="P:tryptophan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1030.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00211">
        <property type="entry name" value="TrpD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005940">
        <property type="entry name" value="Anthranilate_Pribosyl_Tfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000312">
        <property type="entry name" value="Glycosyl_Trfase_fam3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017459">
        <property type="entry name" value="Glycosyl_Trfase_fam3_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036320">
        <property type="entry name" value="Glycosyl_Trfase_fam3_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035902">
        <property type="entry name" value="Nuc_phospho_transferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43285">
        <property type="entry name" value="PTHR43285"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02885">
        <property type="entry name" value="Glycos_trans_3N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00591">
        <property type="entry name" value="Glycos_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47648">
        <property type="entry name" value="SSF47648"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52418">
        <property type="entry name" value="SSF52418"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01245">
        <property type="entry name" value="trpD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="1 4 7" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4 7" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 4" id="KW-0822">Tryptophan biosynthesis</keyword>
    <feature type="domain" description="Glycos_trans_3N" evidence="6">
        <location>
            <begin position="11"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_3" evidence="5">
        <location>
            <begin position="78"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="region of interest" description="Phosphoribosylpyrophosphate binding" evidence="4">
        <location>
            <begin position="87"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Phosphoribosylpyrophosphate binding" evidence="4">
        <location>
            <begin position="94"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Phosphoribosylpyrophosphate binding" evidence="4">
        <location>
            <begin position="112"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="84"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="92"/>
        </location>
        <ligand>
            <name>5-phospho-alpha-D-ribose 1-diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="96"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="124"/>
        </location>
        <ligand>
            <name>5-phospho-alpha-D-ribose 1-diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="170"/>
        </location>
        <ligand>
            <name>anthranilate</name>
            <dbReference type="ChEBI" id="CHEBI:16567"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="229"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC93943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="346" mass="36684" checksum="B3F652AF96B63BD0" modified="2018-07-18" version="1">MNITPQEALLRCIEHREIFHDEMLFLFRQIMSGEMSPVMVAAITTGLRVKKETIGEITAAAQVMREFSTKVPLANTDHLIDIVGTGGDSSHTFNISTASMFVAAAAGARVAKHGGRSVSSSSGSADVLESLGANINLKPEQIAQSIAQTGIGFMFAPNHHAAMKHAAPVRKELGVRTIFNILGPLTNPAGAPNILMGVFHPDLVGIQVRVLQRLGAQHALVVWGRDNMDEASLGAGTLVGELVNGEIREYEIHPEDFGLAMSSNRSFKVANSDESKQKIFEALSNTASPARDIVALNAGMAIYGAGLATSIADGLSRANAVIESGAARAKLDQFVQVTQQLGAHNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1Z0</accession>
    <name>A0A2S9H1Z0_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 6">Imidazoleglycerol-phosphate dehydratase</fullName>
            <shortName evidence="5">IGPD</shortName>
            <ecNumber evidence="5 6">4.2.1.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">hisB</name>
        <name evidence="8" type="ORF">S2091_1178</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + H2O</text>
            <dbReference type="Rhea" id="RHEA:11040"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:57766"/>
            <dbReference type="ChEBI" id="CHEBI:58278"/>
            <dbReference type="EC" id="4.2.1.19"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 5 6">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 6/9.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5 6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the imidazoleglycerol-phosphate dehydratase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.19" evidence="5 6"/>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94005">
        <property type="protein sequence ID" value="PRC94005"/>
        <property type="gene ID" value="S2091_1178"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00011"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004424">
        <property type="term" value="F:imidazoleglycerol-phosphate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07914">
        <property type="entry name" value="IGPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00076">
        <property type="entry name" value="HisB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038494">
        <property type="entry name" value="IGPD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000807">
        <property type="entry name" value="ImidazoleglycerolP_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020565">
        <property type="entry name" value="ImidazoleglycerP_deHydtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23133">
        <property type="entry name" value="PTHR23133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00475">
        <property type="entry name" value="IGPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00954">
        <property type="entry name" value="IGP_DEHYDRATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00955">
        <property type="entry name" value="IGP_DEHYDRATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5 6" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="4 5 6" id="KW-0456">Lyase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000599"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC94005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="204" mass="22634" checksum="06D80DE9E01C324F" modified="2018-07-18" version="1">MQAQQPQSQQRRAEVTRNTNETQIRVAINLDGTGQQKLNTGVPFLDHMLDQIARHGLFDLDIEAKGDLHIDAHHTVEDVGITLGQAFALALKDKAGIRRYGHAYVPLDEALSRVVLDCSGRPGLEFHVPWKRAMIGGFDVDLTHEFFQGFVNHALVSLHIDNLRGENAHHQCETVFKAFGRALRMAVELDPRSAGIVPSTKGCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H212</accession>
    <name>A0A2S9H212_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 15">Cytochrome b</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">S2091_1163</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 15">Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
        <text evidence="15">Binds 2 heme groups non-covalently.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="14">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
        <text evidence="14">Binds 2 heme groups non-covalently.</text>
    </comment>
    <comment type="subunit">
        <text evidence="15">The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="15">Belongs to the cytochrome b family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC93990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93990">
        <property type="protein sequence ID" value="PRC93990"/>
        <property type="gene ID" value="S2091_1163"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045275">
        <property type="term" value="C:respiratory chain complex III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008121">
        <property type="term" value="F:ubiquinol-cytochrome-c reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022904">
        <property type="term" value="P:respiratory electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00284">
        <property type="entry name" value="Cytochrome_b_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.810.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005798">
        <property type="entry name" value="Cyt_b/b6_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036150">
        <property type="entry name" value="Cyt_b/b6_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005797">
        <property type="entry name" value="Cyt_b/b6_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027387">
        <property type="entry name" value="Cytb/b6-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030689">
        <property type="entry name" value="Cytochrome_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016174">
        <property type="entry name" value="Di-haem_cyt_TM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00032">
        <property type="entry name" value="Cytochrom_B_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00033">
        <property type="entry name" value="Cytochrome_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038885">
        <property type="entry name" value="COB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81342">
        <property type="entry name" value="SSF81342"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81648">
        <property type="entry name" value="SSF81648"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51003">
        <property type="entry name" value="CYTB_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51002">
        <property type="entry name" value="CYTB_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 15" id="KW-0249">Electron transport</keyword>
    <keyword evidence="5 14 15" id="KW-0349">Heme</keyword>
    <keyword evidence="11 14" id="KW-0408">Iron</keyword>
    <keyword evidence="12 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 15" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="7 15 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 16" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 15" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="47"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="99"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="132"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="158"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="198"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="259"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="320"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="345"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="370"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="402"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="433"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="domain" description="CYTB_NTER" evidence="17">
        <location>
            <begin position="18"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="domain" description="CYTB_CTER" evidence="18">
        <location>
            <begin position="240"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="14">
        <location>
            <position position="101"/>
        </location>
        <ligand>
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
            <label>b562</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="14">
        <location>
            <position position="115"/>
        </location>
        <ligand>
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
            <label>b566</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="14">
        <location>
            <position position="202"/>
        </location>
        <ligand>
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
            <label>b562</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="14">
        <location>
            <position position="217"/>
        </location>
        <ligand>
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
            <label>b566</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="222"/>
        </location>
        <ligand>
            <name>a ubiquinone</name>
            <dbReference type="ChEBI" id="CHEBI:16389"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR038885-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR038885-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU003385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="PRC93990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="469" mass="52986" checksum="9BEB03087BEECAF9" modified="2018-07-18" version="1">MAFVEKKLPADAPVVDKALNWVDSRFPLTKLWNDQWGQYYAPKNFNFWYIFGSLAMLVLVIQIVTGIFLVMHYKPDATLAFASVEYIMREVPWGWLVRYMHSTGASAFFIIIYLHMARALMYGSYRKPRELVWLFGFAIFLCLMAEAFFGYLLPWGQMSYWGAQVIVNLFGAIPFIGPDLSLWIRGDYVVSDATLNRFFSFHVIAIPLVLLGLVAAHLIALHEVGSNNPDGIEIKDNLDADGHPLDGIPSHPYYSVHDIFGVTVFLVLFSAVVFFAPEMGGYFLESNNFIPADSLKTPLHIAPTWYFTPFYSILRATTSEFLYVVQAGIAGYVSLIYLKTKLPAFVKAAIAALGLLIIIGMMPFGLEAKFWGVVLFGSSVMIMAGMPWLDQSPVKSIRYRPDWHKTVFILFGIAFVVLGYLGVEPPSPVRERISQICAVIYFGFFLLMPWWSAMGTFKPVPSRVTFKPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H227</accession>
    <name>A0A2S9H227_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Antitoxin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1202</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Antitoxin component of a type II toxin-antitoxin (TA) system.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the phD/YefM antitoxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94029">
        <property type="protein sequence ID" value="PRC94029"/>
        <property type="gene ID" value="S2091_1202"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006442">
        <property type="entry name" value="Antitoxin_Phd/YefM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036165">
        <property type="entry name" value="YefM-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02604">
        <property type="entry name" value="PhdYeFM_antitox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143120">
        <property type="entry name" value="SSF143120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009981"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU362080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="86" mass="9588" checksum="297ADA888F18AD18" modified="2018-07-18" version="1">MRILTYSEARNNLKKVLDNSIDDADVTIIHRRDGEDAVVMGLNYYNSLIETLHLTSSPSNAAHLAESIAEYRAGKAVQRKLIATDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H228</accession>
    <name>A0A2S9H228_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative transcriptional regulator BolA superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1183</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the BolA/IbaG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94010">
        <property type="protein sequence ID" value="PRC94010"/>
        <property type="gene ID" value="S2091_1183"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002634">
        <property type="entry name" value="BolA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036065">
        <property type="entry name" value="BolA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01722">
        <property type="entry name" value="BolA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82657">
        <property type="entry name" value="SSF82657"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="81" mass="9072" checksum="8D0F498CBEC7128F" modified="2018-07-18" version="1">MLPTPEQINDYIAAGMQCSHLSVQGDGQHFQATIVSDAFVGKRLIQRHQMVYAVLGDRMREEIHALSMKTLTPEEFAQNNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2D3</accession>
    <name>A0A2S9H2D3_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">30S ribosomal protein S13</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpsM</name>
        <name evidence="8" type="ORF">S2091_1293</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the universal ribosomal protein uS13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94120">
        <property type="protein sequence ID" value="PRC94120"/>
        <property type="gene ID" value="S2091_1293"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.910.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01315">
        <property type="entry name" value="Ribosomal_S13_S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027437">
        <property type="entry name" value="30s_Rbsml_prot_S13_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001892">
        <property type="entry name" value="Ribosomal_S13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010979">
        <property type="entry name" value="Ribosomal_S13-like_H2TH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019980">
        <property type="entry name" value="Ribosomal_S13_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018269">
        <property type="entry name" value="Ribosomal_S13_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10871:SF1">
        <property type="entry name" value="PTHR10871:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00416">
        <property type="entry name" value="Ribosomal_S13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002134">
        <property type="entry name" value="Ribosomal_S13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46946">
        <property type="entry name" value="SSF46946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03631">
        <property type="entry name" value="uS13_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00646">
        <property type="entry name" value="RIBOSOMAL_S13_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50159">
        <property type="entry name" value="RIBOSOMAL_S13_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="5" id="KW-0820">tRNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="92"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00029533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003830"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC94120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="121" mass="13651" checksum="A80715BD75C6905D" modified="2018-07-18" version="1">MARIAGVNIPNHQHTVIGLTAIYGIGRPRSEKICAATGVLTNKKVKDLDDNELEKLRDEIAKFIVEGDLRREVSMSIKRLMDLGCYRGMRHRKGLPCRGQRTRTNARTRKGPRKAAQSLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2E2</accession>
    <name>A0A2S9H2E2_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">50S ribosomal protein L6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rplF</name>
        <name evidence="7" type="ORF">S2091_1300</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 5">This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the universal ribosomal protein uL6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94127">
        <property type="protein sequence ID" value="PRC94127"/>
        <property type="gene ID" value="S2091_1300"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.930.12">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01365_B">
        <property type="entry name" value="Ribosomal_L6_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000702">
        <property type="entry name" value="Ribosomal_L6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020040">
        <property type="entry name" value="Ribosomal_L6_a/b-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036789">
        <property type="entry name" value="Ribosomal_L6_a/b-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019906">
        <property type="entry name" value="Ribosomal_L6_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002358">
        <property type="entry name" value="Ribosomal_L6_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11655">
        <property type="entry name" value="PTHR11655"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11655:SF14">
        <property type="entry name" value="PTHR11655:SF14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00347">
        <property type="entry name" value="Ribosomal_L6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002162">
        <property type="entry name" value="Ribosomal_L6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00059">
        <property type="entry name" value="RIBOSOMALL6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56053">
        <property type="entry name" value="SSF56053"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03654">
        <property type="entry name" value="L6_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00525">
        <property type="entry name" value="RIBOSOMAL_L6_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1 3 4" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 5" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_L6" evidence="6">
        <location>
            <begin position="12"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="domain" description="Ribosomal_L6" evidence="6">
        <location>
            <begin position="90"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC94127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="177" mass="18855" checksum="FEC52537BC2FD01E" modified="2018-07-18" version="1">MSRVGKMPIALPAGTEVSISAAQIVVKGPMGELSQALNGLVKVANDNGSLKFEPVSDAREANAMTGTLRALVNNMVSGVTKGFEKKLNLVGVGYKAQAQGDKLNLSLGFSHPVVHSMPLGVKCETPTPTEILIKGIDRQKVGQVAAEVRAYRQPEPYKGKGVRYADEVVVLKETKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2Y0</accession>
    <name>A0A2S9H2Y0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">RecF/RecN/SMC N terminal domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0955</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94334">
        <property type="protein sequence ID" value="PRC94334"/>
        <property type="gene ID" value="S2091_0955"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003395">
        <property type="entry name" value="RecF/RecN/SMC_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02463">
        <property type="entry name" value="SMC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SMC_N" evidence="1">
        <location>
            <begin position="82"/>
            <end position="711"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="892" mass="99496" checksum="5A8F18B29C779895" modified="2018-07-18" version="1">MSKSISEFKRFLIKSQAAFSEYEKKLAKLVLDNFHEVEASGTAGGKRGKLIAKFIENAGDSASSDLNIEIDASTDDLNRITYLSAIKIKNFRGFSTEKILEFKNPYTFIYGPNGTGKSSLCEALEYCLLGSINEADAKRIDITTYIKNSITKKSDQPLLSGKTSDGKSVAVQADPKRYEFCFIEKNRIDGFARVAANTTAAQQVRLAALFGLEEFNGFSTQFNDNFENYIDSTGKKAKELADKEKQIAGHKAILLQIPEKEKEVKSKQDALLLKYPAYKALDEIKEHISGLDGNGGVTKKNHTEIGRLNNLKLAVDPGIDVISTEILDMTTLIQESKAAKQFLAGYKDQLSLGDLYSAILKNKEKSENHCPACESLLYDGDKIMVPVDPYQNATEKLKQFDVAIKKEARIKDIATQLNDRWPKLVSKVGNLAPAAILVAFAKSVEIDALKVSAENANNPKLKEDVLTMLLSKADLLGELKKAILNFNEAIGKSKSEIKKLENSNTALAKNLEEIVAIKTTIDQNIKNANAANIAIEKFKAENDTLIKLVEIEKPIVSRNIKYLVAYENFREKLLQYNGNLPLNLAADLNDRTLKYYNAINKNDHVSDRLKSLTLPTSPGKKIEIEFEVGQKCDALQILSEGHIRCLGLAILLSKIVRDDLPFLIFDDVVNSIDDEHRSGIIELILGDDEIKKRQLIITTHGEDFVKRLENAIPKIEYKSTVCRIDFLIPVDSKQILVKLDSPRHYLVVAEQSYQDGKIRDCLSYVRKSFEDLLNRLWKKIGNKSHTAQIQVGLRGPGGSPDLMAIASGLHGFLNKKEVTIFQDVIPLLAKMIGKESTHALEWNYLNKGTHEEDKEEEFDISMVKEMLELVMEIDTAVEKSGATPQLLKVVEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H312</accession>
    <name>A0A2S9H312_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">AhpC/TSA family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_0877</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94256">
        <property type="protein sequence ID" value="PRC94256"/>
        <property type="gene ID" value="S2091_0877"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015036">
        <property type="term" value="F:disulfide oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017004">
        <property type="term" value="P:cytochrome complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013740">
        <property type="entry name" value="Redoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08534">
        <property type="entry name" value="Redoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0201">Cytochrome c-type biogenesis</keyword>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015754278" evidence="5">
        <location>
            <begin position="25"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="6">
        <location>
            <begin position="26"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC94256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="170" mass="18611" checksum="AAF561B4F1619059" modified="2018-07-18" version="1">MKLNYIILMMALGVPALQPFEVFAANSALTAFPSTSLPDVDGRAHNFNEWGGKIRVVNFWATWCAPCRNEIPLLSAISREWHAKDVEVIGVAIDGSDDVRAFINEAKIAYPVLLAEQQGQGLMQSGGNAMGALPFTLLLDRRGNIIQRHAGVLDARLLKQWLAEATAKPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H338</accession>
    <name>A0A2S9H338_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0974</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94353">
        <property type="protein sequence ID" value="PRC94353"/>
        <property type="gene ID" value="S2091_0974"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="78" mass="8683" checksum="7CE56CD9E69E5C9F" modified="2018-07-18" version="1">MGTHLHNPDQFVDYADIASMLSTLKSEVNFLAQMNGFNERELHAAAVLHSLTQGHDPVSTDKLIELLNAIKAHKKPFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H378</accession>
    <name>A0A2S9H378_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF87 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1041</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94420">
        <property type="protein sequence ID" value="PRC94420"/>
        <property type="gene ID" value="S2091_1041"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008571">
        <property type="entry name" value="HerA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002789">
        <property type="entry name" value="HerA_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42957">
        <property type="entry name" value="PTHR42957"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01935">
        <property type="entry name" value="DUF87"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF87" evidence="1">
        <location>
            <begin position="151"/>
            <end position="410"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="581" mass="64781" checksum="CFE9DB2889662DF2" modified="2018-07-18" version="1">MTNAALQFQDSDRLGRVAAVDTSRVLISVENHQHMTTIAVGNLIAIQGRTAAEFLIGIVERATRSVSEKLLVDEPTEEGVIPVGESQEDFIKTVLIGTYRTVDGSFSNTFKRGADCFPQVDRDCFHVNSKNLQQFMNLLSMNVKEGERLTLGHFMADQTAIAVANGDKFFQRHAAILGSTGSGKSWAVALMLERAAALKSANLIVLDMHGEYSTLCQGPNAIAQQYRIAGPGDLDKPDDGCLFLPYWLLNREEMLALILDRSDDNAPNQAARFTEHVRSLKEQVLKESKKEDVLATFTVDSPIPYPIKSLQALLNEDDTGTKKGANDKDIKGDWNGKLSRFIIRMKAKTDDRRCGFMFQPPAMCNDYDWLQKMLGSLFAVSDTQRGIKIIDFSEVPSDVLPIVTGVLARLLYSIQFWMDKESRHPLTIVCDEAHLYLPVRDSAEAAEKRALESFERIAKEGRKYGVSLLVVSQRPSDVSRTILSQCNNFLVLRLTNDQDQSVVKRLMPESMAGITDILPLLDLGEALLLGDSILLPTRIKLDRPKIEPASATRQFWTDWANQVPKVDAIPKAVEALRRQVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H381</accession>
    <name>A0A2S9H381_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">S-adenosylmethionine synthase</fullName>
            <shortName evidence="11">AdoMet synthase</shortName>
            <ecNumber evidence="11">2.5.1.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">MAT</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Methionine adenosyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">metK</name>
        <name evidence="17" type="ORF">S2091_1060</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>ATP + H2O + L-methionine = diphosphate + phosphate + S-adenosyl-L-methionine</text>
            <dbReference type="Rhea" id="RHEA:21080"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="EC" id="2.5.1.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
        <text evidence="11">Binds 1 potassium ion per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="11">Binds 2 divalent ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 11">Amino-acid biosynthesis; S-adenosyl-L-methionine biosynthesis; S-adenosyl-L-methionine from L-methionine: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Homotetramer; dimer of dimers.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11 12">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11 13">Belongs to the AdoMet synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.6" evidence="11"/>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94439">
        <property type="protein sequence ID" value="PRC94439"/>
        <property type="gene ID" value="S2091_1060"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00315">
        <property type="reaction ID" value="UER00080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004478">
        <property type="term" value="F:methionine adenosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006730">
        <property type="term" value="P:one-carbon metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006556">
        <property type="term" value="P:S-adenosylmethionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00086">
        <property type="entry name" value="S_AdoMet_synth1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022631">
        <property type="entry name" value="ADOMET_SYNTHASE_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022630">
        <property type="entry name" value="S-AdoMet_synt_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022629">
        <property type="entry name" value="S-AdoMet_synt_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022628">
        <property type="entry name" value="S-AdoMet_synt_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002133">
        <property type="entry name" value="S-AdoMet_synthetase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022636">
        <property type="entry name" value="S-AdoMet_synthetase_sfam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11964">
        <property type="entry name" value="PTHR11964"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02773">
        <property type="entry name" value="S-AdoMet_synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02772">
        <property type="entry name" value="S-AdoMet_synt_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00438">
        <property type="entry name" value="S-AdoMet_synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000497">
        <property type="entry name" value="MAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55973">
        <property type="entry name" value="SSF55973"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01034">
        <property type="entry name" value="metK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00376">
        <property type="entry name" value="ADOMET_SYNTHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00377">
        <property type="entry name" value="ADOMET_SYNTHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 11 12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 11 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 11" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="10 11 12" id="KW-0630">Potassium</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11 17" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="S-AdoMet_synt_N" evidence="14">
        <location>
            <begin position="4"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="domain" description="S-AdoMet_synt_M" evidence="15">
        <location>
            <begin position="117"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="domain" description="S-AdoMet_synt_C" evidence="16">
        <location>
            <begin position="235"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="region of interest" description="Flexible loop" evidence="11">
        <location>
            <begin position="100"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="16"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="18"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="44"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="57"/>
        </location>
        <ligand>
            <name>L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="100"/>
        </location>
        <ligand>
            <name>L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="167"/>
            <end position="169"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="232"/>
            <end position="233"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="241"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="247"/>
            <end position="248"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="264"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <note>ligand shared between two neighboring subunits</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="268"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <note>ligand shared between two neighboring subunits</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="272"/>
        </location>
        <ligand>
            <name>L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU004462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF02772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF02773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="PRC94439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="389" mass="42634" checksum="E88B9F38B574BAA4" modified="2018-07-18" version="1">MANEYLFTSESVSEGHPDKVADQISDAILDAILAQDPHARVAAETLCNTGLVVLAGEITTHANVDYINVARETIKRIGYDNTDYGIDYRGCAVMVCYDKQSPDIAQGVDEGRGLDLDQGAGDQGLMFGYACDETPELMPAAIYYAHRIVERQSQLRKDGRLPWLRPDAKSQVTLRYVDGRPVGIDTIVLSTQHAPEMHHKAIEEAAIEDIINPVVPKEWLKNTRYLINPTGRFVIGGPQGDCGLTGRKIIVDTYGGACPHGGGAFSGKDPTKVDRSAAYAARYVAKNIVAAGLARQCQIQISYAIGVAKPINITVYTEGTGIIPDEKIAELVHQFFDLRPKGIVQMLDLLRPIYQKTAAYGHFGRDEPEFTWERTDKAALLRDAAGLKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3K9</accession>
    <name>A0A2S9H3K9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0554</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94551">
        <property type="protein sequence ID" value="PRC94551"/>
        <property type="gene ID" value="S2091_0554"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="76" mass="8937" checksum="8264E80B6076C899" modified="2018-07-18" version="1">MIKKKNRQLTELLASTDIVIPSLLGKNFRIENDVKIYQVVGMRWRSQEIVLKEEATEKMRTMVGDEFLRLATRVEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3L2</accession>
    <name>A0A2S9H3L2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Agmatinase: agmatinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_0572</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the arginase family. Agmatinase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94569">
        <property type="protein sequence ID" value="PRC94569"/>
        <property type="gene ID" value="S2091_0572"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016813">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901564">
        <property type="term" value="P:organonitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005925">
        <property type="entry name" value="Agmatinase-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006035">
        <property type="entry name" value="Ureohydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023696">
        <property type="entry name" value="Ureohydrolase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020855">
        <property type="entry name" value="Ureohydrolase_Mn_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11358">
        <property type="entry name" value="PTHR11358"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00491">
        <property type="entry name" value="Arginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036979">
        <property type="entry name" value="Arginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52768">
        <property type="entry name" value="SSF52768"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01230">
        <property type="entry name" value="agmatinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01053">
        <property type="entry name" value="ARGINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51409">
        <property type="entry name" value="ARGINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC94569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="318" mass="34172" checksum="00B2E186A035AE3C" modified="2018-07-18" version="1">MDSTIKGDGAIRRTSVYGSSIENTYAGVLSFMRRNYTRDLTGVDVVISGIPLDLATTFRSGARQGPAAVRAASVQLSELAPYPWGFNPFDDLAVIDYGDCWFDAHNPLTIAPSIVEHARTILASGAKMLTFGGDHFVTYPLLKAHVEKIGQPLSLIHFDAHCDTWADDEPASLNHGSMFYKAIKEGLIDPATSVQVGIRTWNDDFMGVNIIDAPWVHAHGAQATLEKILNIVGKCPTYLTFDIDCLDPAFAPGTGTPVPGGLSSAQALHIIRGMGPVNLVGMDVVEVSPAFDQSEITALAAAHIAADLLCVLRNQKIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H431</accession>
    <name>A0A2S9H431_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0629</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94626">
        <property type="protein sequence ID" value="PRC94626"/>
        <property type="gene ID" value="S2091_0629"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009387">
        <property type="entry name" value="HigB-2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06296">
        <property type="entry name" value="RelE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018634">
        <property type="entry name" value="UCP018634"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="125" mass="14139" checksum="C0C0EE49F59FF86E" modified="2018-07-18" version="1">MQIYQTKWFARWAIKEGLSEQTLRDAVTEMEQGLIDANLGGNVVKKRIGVSGRGKSGGVRTILAFKIKKKAFFLYGFAKNQRDNIGDKELQTLKVLAAHFLTYDNRALDKAIKAQELIEVTYDQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H444</accession>
    <name>A0A2S9H444_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acetyltransferases including N-acetylases of ribosomal protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0757</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94754">
        <property type="protein sequence ID" value="PRC94754"/>
        <property type="gene ID" value="S2091_0757"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="2"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="172" mass="19284" checksum="56FDE1B12E4611CE" modified="2018-07-18" version="1">MIKIRTLELSDAENLLSFEFENRAWFEQHIAPRPDSWFSKEGVLAHIRSYLKAQQQGTFHACVVLDETEQKIIARANLRDIDQDAGTAEIGYRIAQALTGKGLASAATKHLMKLAYSEWQLKQLSGFVSLANPASARVLEKNGFNNVGPGERVAVLKHGTFACDEYRHLRVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H452</accession>
    <name>A0A2S9H452_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Insulinase (Peptidase family M16)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_0753</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94750">
        <property type="protein sequence ID" value="PRC94750"/>
        <property type="gene ID" value="S2091_0753"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011249">
        <property type="entry name" value="Metalloenz_LuxS/M16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011765">
        <property type="entry name" value="Pept_M16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007863">
        <property type="entry name" value="Peptidase_M16_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00675">
        <property type="entry name" value="Peptidase_M16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05193">
        <property type="entry name" value="Peptidase_M16_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63411">
        <property type="entry name" value="SSF63411"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015512813" evidence="3">
        <location>
            <begin position="25"/>
            <end position="963"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M16" evidence="4">
        <location>
            <begin position="52"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M16_C" evidence="5">
        <location>
            <begin position="210"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M16_C" evidence="5">
        <location>
            <begin position="703"/>
            <end position="857"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="854"/>
            <end position="883"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="854"/>
            <end position="875"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF05193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC94750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="963" mass="107367" checksum="7378DC9E6A80F073" modified="2018-07-18" version="1">MTTFSLRKIFAGALLLALTWSAQSAITLSDPLPINPLLKMGKLENGLTYYIQKNSKPEKRVELRLVVKAGSILEDDDQQGLAHFTEHMAFNGSRHFKKHELISYLQSIGIKFGADLNAYTSFDETVYILPVPTTKKENLETGFLVLEDWAQGLTMNDADIDSERHIILEEARLGKGAGDRMNKQLYPALFNGSKYAERLPIGKEDIISNFKHDAIKRFYADWYRPDLMAVVVIGDIEPEQAEQMIKAHFAQLKNPANERPRNYAKIPTRDASAGLVITDKEATNNVVMIRYPVQPSTPDKSIADYRQSLIKNLSSAILNQRLQELTQQATPPFIGGGSSIGALAHGYESFSSAAIIGRTGVESAITALIQENERARQFGFSSAELERTKKNHLRFFETAYNERDKSNSSEYAAEYIRHFLTEESIPGIVNEYAYATELLPGITLDEVNHYAQKNIPDNIPKLATYLGSNKEGEIIPTNTQLLNWVNSAEKAPVLANSDKAIPTSLLAQAPNAGSITAETVNVRLGTTELTLSNGLKVILKPTDFKSDQVLLSASRFGGLSLFDDADKYNALYATAVTQSMGLASYTPTDLQKILAGKSLSFNTSLSNYTEHLSGYAASSDIETLFQSIYLRFANPRKDPDLYTAFISGMQDLTKNSMARPESVFSNTLSTTLYNNHPRLSLAPKPDDFTHINLDRTSAIYGERFNSAKGFTFILIGSFDLEKIKPLIATYLASLPTTELSTSYHDLNIRPVTGVVKKEVHSGSEPKSQVSIIFTGPANYSKEENMRFNALIEVMNLRITDVLREKLTLIYSGGMSGSIDRIPYQNYRIAINLPCGPDNVDKVIAATFAEIEKIKSETPPEPVKDQGQDQDQKQAKEKINSAGPTQEELNKVKLNWIKNHNIAMRTNEQWLRYLQDATLFNTDTTELLTVENRVNAITLADVRESAKRYLNTENYVQVVLYPEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4G6</accession>
    <name>A0A2S9H4G6_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">TGc domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0052</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94857">
        <property type="protein sequence ID" value="PRC94857"/>
        <property type="gene ID" value="S2091_0052"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024618">
        <property type="entry name" value="DUF3857"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002931">
        <property type="entry name" value="Transglutaminase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12969">
        <property type="entry name" value="DUF3857"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01841">
        <property type="entry name" value="Transglut_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="SMART" id="SM00460">
        <property type="entry name" value="TGc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="SSF54001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015733934" description="TGc domain-containing protein" evidence="1">
        <location>
            <begin position="22"/>
            <end position="1403"/>
        </location>
    </feature>
    <feature type="domain" description="TGc" evidence="2">
        <location>
            <begin position="338"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="1403" mass="158214" checksum="E919BCC823BC85A5" modified="2018-07-18" version="1">MRLKLIVLVIFFPLFSSLVGASQTHSNEPKSSAQANGFDQNPLLPKWSHPLAEIPVTTRTDPVVIRLAETQIQLGESSDVLVNRVIQVNDRSALARIGQYGIDYYPIYQKLHLHRIAIIRGDKVLDRSASVNIRNLQRESNLESGMYGGATTVQLLLDDVRIGDSLWITYSQEGDNPVFGNSWASNFGWDSTDPIELRRITLLHPVKRPLYWKQLGDYLKTEIKPVVDEKNGIERLRFEERGIDAVEMEQSIPSNYSPTRFLEFSEHKNWHQVALWADGLFPKGKAGPELSALIGQFKKEPTATERVSAALQWVQNEIRYFSVSIGENSHRPQPPDTVIKRRYGDCKDKTYLLVTILSQMGIEARPVLLSAQSPEYPLKVQAAPIWFDHVIVQLKIDNHIYYVDPTRTGENSPLDKLPSAMPGAAGLVVDSSTQQLTILPVDTDIGPMYEHVENINITDFSGDAELELHKLYRGAYAEWAREHYKSISASEVRKEMLSIYEKKYPGVSLTDSPVTHDNPLKNRYEIIGRYKLPNPVVHKNARFTIAYDSQILNGALRIPDNIGRNFPLSLGRSKYVARYQLNVDWPERVRAIDTPSFTVVDNDFFRLDEDYTNRGNRLSYLMNFVVKTDVVEAKDVPELHAQAKLLEPYENSGFSINESALTDVDYKTFSFRNYDAKRNTTNLMSRFAELKDSKKAKEYTDSDKCLVVIDALRLVDYLTTEDVRKTLTEMESKISGKIDGKDEVCISQYLFSQGRYKEGIEHFGLAGTIADDSMLVQQLAWARFYEGDAEAALVEMQRFLNARLKKSNNATNYFDLANEIALYQRIGKPLPESTMRFAVDFPEGPWPRPILAMQTGMMSNSDLIKIADALPKDTREIALSEAWFYIGQKHLSTKDNVAAEAAFRWLNTGGIRSLDIYFPAKNEYKRLQISDADCTTGMSAFDVNNYPMAIAAWQRGAEAGRACSQLEIGLANYYGEGVSKDFDKAFKWLGLSAQQNNPRAISMLGQMYKYGEGVAQDSKKSFEYYSLAAGMGNPYAQLNLGDFYDSGNIVERDYSKSFNLYSSAAEQGVAKAQLNLSYYFQNGTGVQRDAHLAFFWGSRAVVQSYIPAILNLGYMYEKGIGIAKNNEIALQYYRVAADNGDRIAQRNLGLMYDNARGVKKNSQEAVVWYRKSAEQGFALAQFNLGYAYDVGRGVSINKSEAQKWYLKAAEQGNTDALFSLGYNYQFGDGVKQDYIEAMKWFRKGVDSNSDKSMNSIGIMYAKGQGVPIDLVEAIKWHEKAAKLGNLEAINTLGVYYRDGVGVQQDENKAMKYFMRAANLSNPDAQSNLAQVYFEGQGVAKDNFQAYKWWVISASIAEVNDYSYRASREGIAKVSKLLTSEQIEAAEKEVIEWSRSSPSNDGSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4K5</accession>
    <name>A0A2S9H4K5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DnaJ domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0092</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94897">
        <property type="protein sequence ID" value="PRC94897"/>
        <property type="gene ID" value="S2091_0092"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="SSF46565"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="328" mass="37565" checksum="BDF2E8067982D0CD" modified="2018-07-18" version="1">MKTPVSSVINIEQKQSATPLSAEQQLFNNLIKKIDMQRQQLSDWQATVSSYEQKYASEYVPLYSAYNQHRTDLVLLLDAAYFDAIFNQTDQEKLSGFISSIAVELMNKDNGAPQLKAIFNRHHHTDIAVVNESEELEELDSTQDYVEDVPDYSAAKKMARQRAQQARLEKQEQKGSQSVRAVYRKLASSLHPDKEQDPLERVRKTGLMQRVNMAYANGDLLQLLELQLELEQMDQARLNTLNELNLNHYNQVLAGQSDDLAMEIRQSQSGFKARFQLGDKANLAPAFLLAELTREIAQMKKHTSGFARDLRELKDVKNIKAWLKTYRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4L7</accession>
    <name>A0A2S9H4L7_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 13">Tetraacyldisaccharide 4'-kinase</fullName>
            <ecNumber evidence="3 13">2.7.1.130</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12 13">Lipid A 4'-kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">lpxK</name>
        <name evidence="15" type="ORF">S2091_0103</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 13">Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 13">Glycolipid biosynthesis; lipid IV(A) biosynthesis; lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 6/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the LpxK family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.130" evidence="3 13"/>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94908">
        <property type="protein sequence ID" value="PRC94908"/>
        <property type="gene ID" value="S2091_0103"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00359">
        <property type="reaction ID" value="UER00482"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009029">
        <property type="term" value="F:tetraacyldisaccharide 4'-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009245">
        <property type="term" value="P:lipid A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00409">
        <property type="entry name" value="LpxK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003758">
        <property type="entry name" value="LpxK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42724">
        <property type="entry name" value="PTHR42724"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02606">
        <property type="entry name" value="LpxK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00682">
        <property type="entry name" value="lpxK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 13 15" id="KW-0418">Kinase</keyword>
    <keyword evidence="6 13" id="KW-0441">Lipid A biosynthesis</keyword>
    <keyword evidence="5 13" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="11 13" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="14" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 13" id="KW-0808">Transferase</keyword>
    <keyword evidence="14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="63"/>
            <end position="70"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00029757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="PRC94908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="338" mass="37177" checksum="9872CD24BE61D577" modified="2018-07-18" version="1">MTENRFASAIMHAWMQRGWLAYLAWPVAQLFGLLLKLRVLMYRLGWLQQQKLAVPVIVVGNIFVGGTGKTPFTQWLLQQLKDAGYTPGVISRGYGSKNDAPCVVLPDSLASQVGDEPILLAQHSACPVVVGRNRADAGRALLAAFPTVNVIIADDGLQHLALARDIEIMLFDSRGVGNGWLLPAGPLREPITRRRDITVANLNEGEQISATLPSDTVRMQLKGTRARQLLDANQTRDLSSLDGNLNIIAAAGIGNPERFFTMLRQQGVRFSSLPLPDHFSYTPNPFANLTADMILITEKDAVKCRQLKEIANDPRIWVVAVEAQIETSVVVKILQKLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4S1</accession>
    <name>A0A2S9H4S1_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF1801 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0136</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94941">
        <property type="protein sequence ID" value="PRC94941"/>
        <property type="gene ID" value="S2091_0136"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014922">
        <property type="entry name" value="DUF1801"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016786">
        <property type="entry name" value="YdeI_bac"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08818">
        <property type="entry name" value="DUF1801"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF021308">
        <property type="entry name" value="UCP021308"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF1801" evidence="2">
        <location>
            <begin position="18"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="174"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="196" mass="22622" checksum="150161A1F57785A9" modified="2018-07-18" version="1">MKTMNPKVDGYFSKAKTWQEELEKLRMIVLDCPLNEELKWGVPCYSFQESNVVLIHVFKEYCAVLFFKGALLKDPNGILIQQTENTQAGRQIRFTNVQEIVKMKTILKAYIHEAIEVEKAGLKVSFKKTDEFILTEEFQHKLDQIPALKTAFEALTPGRQRAYLLHFSAPKQSKTRESRIEKSMPQILNGKGLNDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4U1</accession>
    <name>A0A2S9H4U1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Microcystin-dependent protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95005">
        <property type="protein sequence ID" value="PRC95005"/>
        <property type="gene ID" value="S2091_0200"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1340.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011083">
        <property type="entry name" value="Phage_tail_collar_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037053">
        <property type="entry name" value="Phage_tail_collar_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07484">
        <property type="entry name" value="Collar"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Collar" evidence="1">
        <location>
            <begin position="6"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC95005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="181" mass="19196" checksum="272275AA60E9C8E0" modified="2018-07-18" version="1">MEPFIGEIKICAFQFAPRGWAFCDGSMLAINQNQALYSLLGAQFGSSTSSSFALPDLRGRVAVHQSPSYPMGAMAGEETVTLTNDTIPTHSHQFVVSTTPANQLNVGIDQENILATSNLYSPTNPAIQGPGKNLYTAASNLTPLQASICSNTGSGAAHENMQPSLVINYIIALSGIYPTRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4Y3</accession>
    <name>A0A2S9H4Y3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">GGDEF: diguanylate cyclase (GGDEF) domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0239</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95044">
        <property type="protein sequence ID" value="PRC95044"/>
        <property type="gene ID" value="S2091_0239"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="SSF51206"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="1">
        <location>
            <begin position="19"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="2">
        <location>
            <begin position="195"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC95044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="326" mass="35888" checksum="155C5F59CE8E9360" modified="2018-07-18" version="1">MELLKLFANSDYRARNLQLFHDISESDLIAINKLIASCCIMLVKAEQAVITAHTTDNRLYIVLNGTLEVQSHENTGGSAASNVQFLAGECVGELSVLDDEDQPHTIIAVGDSELLVIEADTLWQLIDESNGVARNLLRLLSFRIRTTNALLRRRHKVGEFYRQMSMIDGLTGIHNRAWLHSQLPQLIERSHASCNPLSIIMADLDHFKLFNDTHGHIIGDDAIQSAAKILNSTLRPTDFAVRFGGEELLVILPDTAKEACFSVAERLCSKLAQTTVLNDVHLPLPHITASFGVATLAAGQDIFTFIAAADTALYRAKNAGRNQVSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H510</accession>
    <name>A0A2S9H510_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Amino acid transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_0270</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95075">
        <property type="protein sequence ID" value="PRC95075"/>
        <property type="gene ID" value="S2091_0270"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="30"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="59"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="100"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="145"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="175"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="215"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="248"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="295"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="356"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="378"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="412"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="439"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="476"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="506"/>
            <end position="524"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC95075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="535" mass="57995" checksum="66735D5F8954CD92" modified="2018-07-18" version="1">MSARQNETSSSQEKLPTQGKFKKQLTLTDLTFIGLGAIFGSGWLFAASHVATIAGPAGIYSWIIGGLAVLLLGIVYCELGAALPKAGGVIRYPVFSHGELIGYLMGSITLIAFSSLIAIEVVAARQYAAAWFPSLNQVGTSSPSLSGWGLQFALLCFFFYLNYFSVKTFAKSNNIISIFKFMVPLLVIGVLFSFFKPENLTVQGIAPFGVTGVQAAISAGGIIFAYLGLTPIVSVAGEVENPQRTIPIALILSVVLSTIIYVLLQLAFMGSIPTELLAGGWGNIAQHFSLPYRDIALMLGVGWLAFLVVSDAVISPSGTGNIYMNATPRVVYGWARSGTLFNVFTRVDAESGIPRPALWLTFILSIFWTLPFPSWETLINVVSAALVLSYAIAPVTAAGLRRNAPHLYRPFYVRGFAVIAPLSFIISALIVYWSGWNTVSWLLGLQIVLFAVYVLCKKFVPVHNVSFKQQVFSSMWLIGFYVLTIVASYLGSFGGKQIVPQPWDTVMVAVMALLVFYWGAYTCLPKANLPADDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H532</accession>
    <name>A0A2S9H532_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glucokinase</fullName>
            <ecNumber evidence="1">2.7.1.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Glucose kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">glk</name>
        <name evidence="3" type="ORF">S2091_0171</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + D-glucose = ADP + D-glucose 6-phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17825"/>
            <dbReference type="ChEBI" id="CHEBI:4167"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61548"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.2"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the bacterial glucokinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.2" evidence="1"/>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94976">
        <property type="protein sequence ID" value="PRC94976"/>
        <property type="gene ID" value="S2091_0171"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004340">
        <property type="term" value="F:glucokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005536">
        <property type="term" value="F:glucose binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00524">
        <property type="entry name" value="Glucokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003836">
        <property type="entry name" value="Glucokinase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02685">
        <property type="entry name" value="Glucokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00749">
        <property type="entry name" value="glk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="1 3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="12"/>
            <end position="17"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU004046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="324" mass="35046" checksum="5D735DAD04504698" modified="2018-07-18" version="1">MTYLRSYPNLLADIGGTNARFALETAPGKHEAILVLPCAHYPTLSDAIRAYLTSPVAAGVKIKKAGVAIANPVHSDVVQMTNHHWSFSIQAVQKEFDFQTLLVVNDFKALAMALPFLDHTQKYQVGTGQPQNNSAIGLLGAGTGLGVSGLIPTKHGWVALDSEGGHTSFSPTNQREMSILQFALQKYKHVSSERLMSGAGIQLIYQALASNQNLTVDDIDTPEITRRGLNNECPVCREVLSTFCELLGTMASNLAITLGAKGGIYIGGGIVPRLGEFFSTSNFRQRFEQKGRFANYLGQIPTYVITEPYPAFIGVSALLAQTDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H533</accession>
    <name>A0A2S9H533_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">GxxExxY: GxxExxY protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0246</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95051">
        <property type="protein sequence ID" value="PRC95051"/>
        <property type="gene ID" value="S2091_0246"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026350">
        <property type="entry name" value="GxxExxY"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13366">
        <property type="entry name" value="PDDEXK_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04256">
        <property type="entry name" value="GxxExxY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC95051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="125" mass="14406" checksum="76797061BB1620FC" modified="2018-07-18" version="1">MDNEVWYKLECLQIQRAVFNVYKNMGRGHQVTDYKASLIDEFSKLGIPFTEQPQPNHCQLEKFNEPYSPHFICHGIIAVKIKVLPATHHEHKTRIGNYLKASKTRLGILANFGCHPRATVEKFAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H588</accession>
    <name>A0A2S9H588_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Methyltransferase domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0350</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-independent O-methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95155">
        <property type="protein sequence ID" value="PRC95155"/>
        <property type="gene ID" value="S2091_0350"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016461">
        <property type="entry name" value="COMT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013217">
        <property type="entry name" value="Methyltransf_12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08242">
        <property type="entry name" value="Methyltransf_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51683">
        <property type="entry name" value="SAM_OMT_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_12" evidence="2">
        <location>
            <begin position="186"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="212"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC95155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="359" mass="39558" checksum="3808FC7D3FFF13E8" modified="2018-07-18" version="1">MLNKNFSPKNQSAFSARFEAQKIAFGPVVFQCVHYAWKRGMLQALSDAGQSGLSVAELSATKCWTDYALKVVLETCLSAGVVYLQDGNYVLDKTGYCILTDKITQINFDFNQDVCYEGLAKLAESLDKEQPIGLNVLGPWPTIYEGLSELPEPAKASWFAFDHHYSDTSFPTILADIFATAPKHVMDIGANTGKFSCAALAYNSAVQLHLVDLPIQLAVAEKSLQDAGVRERAHLHPTDLLNAEQPLKSGMDVIWMSQFLSCFSEAVIATILQRAVAALGPKGQLIIMDTFWDRQRYDIASYCLINTSPYFTSMASGNSKIYESTDYIRLAELAGLELLTVRDDIGYCHSLLRFGVASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5M3</accession>
    <name>A0A2S9H5M3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ABC-type Fe3+ transport system periplasmic component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_0477</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95282">
        <property type="protein sequence ID" value="PRC95282"/>
        <property type="gene ID" value="S2091_0477"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006811">
        <property type="term" value="P:ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055072">
        <property type="term" value="P:iron ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026045">
        <property type="entry name" value="Ferric-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006059">
        <property type="entry name" value="SBP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13416">
        <property type="entry name" value="SBP_bac_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002825">
        <property type="entry name" value="CfbpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="4 6" id="KW-0408">Iron</keyword>
    <keyword evidence="1" id="KW-0410">Iron transport</keyword>
    <keyword evidence="2 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015640356" evidence="7">
        <location>
            <begin position="29"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="225"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="226"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR002825-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC95282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="338" mass="37231" checksum="E75B44982F63C32F" modified="2018-07-18" version="1">MKKLNHLTRLISAALFTSLLATSLTASAEQVVVYSARNEQLIKPLFDAYTKQTGVQIKFVTDKEGPLMERLKAEGKQTPADIFMTVDAGNLWQAAQMDLFQPLTSSTLTANIPAHLRDTNNQWFGLSIRARTIFFNTKQVTPASLSTYEELADPKWKGKLCLRTSKKIYNQSLTAMLIAEHGAIKAEQIVKGWVSNLATPVFSDDTKMLEAIAAGQCEVGIANSYYYGRLMDKWPTLPIGIFWANQNNGGVHVNISGAGVTKFAKNPTGAQKLLEWLSSSQAQNLYTDGAMEFPANPAIPADPRLVKWGPFKQNLINVSKAGELQAEAVKLMDRAGYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GS72</accession>
    <name>A0A2S9GS72_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4733</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000057">
        <property type="protein sequence ID" value="PRC90559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90559">
        <property type="protein sequence ID" value="PRC90559"/>
        <property type="gene ID" value="S2091_4733"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="55"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="127" mass="13192" checksum="B1C1882563DCF33C" modified="2018-07-18" version="1">MTLGSSLAGAIGSVITRIGDQVTKAQNTDNDRLKGALALKAGYDTYKLVNGGKVSETTTESLKPNPQNSGDGFGVSVNLGVSRSQQDSNNSATQARGTRSKPARSTSPPEKVTSAWKVPNCKPTISP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSB4</accession>
    <name>A0A2S9GSB4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4706</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000048">
        <property type="protein sequence ID" value="PRC90586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90586">
        <property type="protein sequence ID" value="PRC90586"/>
        <property type="gene ID" value="S2091_4706"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="24"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="255"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="294" mass="32597" checksum="929AA758448AE671" modified="2018-07-18" version="1">MVNSAPFMSTDPQPSIFSLLKRHIWRFAVVGIVCAAIALGTAMLRPLQWKADLLFQIGQVGNAAGILIDPNNVVQRIKFPGFAAQILSALNLPEDLNADPRSKLISSSFTASVVKGGSLINLSVNGFSKEDAIKNLQASFLLIEKEHEQLLTPLVSRLKKNLDEVNENISKIEIERQSIFEPISKINTPAMIDKKFSESIVLVNTLKVRDSELHGLHDQKNSIEDQLNPSHTFNTKIFDKIFVSFNPESRNISTFTLLGLLFGLIFAGIWAVLNDKELLVALHGLFYDSNEIST</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSD7</accession>
    <name>A0A2S9GSD7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">F0F1-type ATP synthase subunit I</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_4647</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000041">
        <property type="protein sequence ID" value="PRC90639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90639">
        <property type="protein sequence ID" value="PRC90639"/>
        <property type="gene ID" value="S2091_4647"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005598">
        <property type="entry name" value="ATP_synth_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03899">
        <property type="entry name" value="ATP-synt_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="29"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="62"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="91"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC90639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="112" mass="11964" checksum="828FFA6E9282A387" modified="2018-07-18" version="1">MMRIVMLQICAAFVVAIIAACIGGYASGFSALLGGLSYAIPNALFALRLYAGTLKPGGASPVTFFVGEFAKILTTIALLAAVGWLYHDVHWLAFLAGFIVVLKSYFILLFRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSL7</accession>
    <name>A0A2S9GSL7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ABC transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_4593</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000038">
        <property type="protein sequence ID" value="PRC90700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90700">
        <property type="protein sequence ID" value="PRC90700"/>
        <property type="gene ID" value="S2091_4593"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-1278">Translocase</keyword>
    <feature type="domain" description="ABC transporter" evidence="7">
        <location>
            <begin position="11"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="7">
        <location>
            <begin position="336"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="43"/>
            <end position="50"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="368"/>
            <end position="375"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC90700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="588" mass="64526" checksum="2F0E3D2B85FB522D" modified="2018-07-18" version="1">MDSNRASGDAITISALQHQFADQIALRGLNCSIRRGIITGIVGPDGAGKTTLMRLMAGLLKATSGTIQVEGLSPINDASALRPQLGYMPQKFGLYEDLTVQENLNLYADLRDVTGAARQQSFQQLLAFTDLARFTDRPAGKLSGGMKQKLGLACTLLGSPRVLLLDEPSVGVDPISRRELWKMVGELAQQGMTVVWSTSYLDEAELCGEVLLMNEGKLEYQGTPGALIERMRGRSVQLRGIAGNRRHVLQQALRAPEVIDGVLQGQALRLVLKEAAVYPPINVLNAGEHAHFIEVTPRLEDAFIDILGGGPGGDSVLAAHMPEARLDPAVDPDAVIEAHQLTRRFGDFIATDHVDFRVKRGEIFGLLGPNGAGKSTTFKMMCGLLRPTSGWAKVMGIDLKQSASQARRQLGYMAQKFALYGNLSVQQNLYFFSGIYGLRNQAQRNMVDDMVRVFNLQPYLNTPAGSLPLGFKQRLALSCAIMHQPPLLFLDEPTSGVDPITRREFWTHINGLVDKGVTVMVTTHFMDEAEYCDRIGLIYRGRTIAAGTPDQLKQLATLPDETEITMEDAFIRLVERDDAQRRSSNVDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSQ9</accession>
    <name>A0A2S9GSQ9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4554</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000037">
        <property type="protein sequence ID" value="PRC90728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90728">
        <property type="protein sequence ID" value="PRC90728"/>
        <property type="gene ID" value="S2091_4554"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="63"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="106"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="130" mass="13838" checksum="81FD1AC3D37C3B05" modified="2018-07-18" version="1">MKNREIDPLKPTKTASLLSLFTSGGTLICCALPALLVALGAGATLSSLISFVPQLVWFSENKTGVFGTATVMLIISGIMQWRARSLPCPLDPVLAVACARARKTSLLIYLFSVGMYLLGGFFAFVAPLLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSS7</accession>
    <name>A0A2S9GSS7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Threonine dehydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_4572</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000037">
        <property type="protein sequence ID" value="PRC90746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90746">
        <property type="protein sequence ID" value="PRC90746"/>
        <property type="gene ID" value="S2091_4572"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="PLP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="Trypto_synt_PLP_dependent"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="SSF53686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PALP" evidence="3">
        <location>
            <begin position="19"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC90746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="320" mass="34503" checksum="E8450426E6BD8BE2" modified="2018-07-18" version="1">MLNLPTYDDVIAASRRIDGHAHCTPVMTSRIINEELGAEVFFKCENLQRMGAFKYRGAFNALSKFDERQRKAGVVAFSSGNHAQAIALSAALLGIPATIIMPNDAPAAKIAATRGYGGKVVIYDRYTEDREQIGRDLAEKHGFTLIPPYDHPDVIAGQGTAAKELFEEVGELDVLFVSLGGGGLLAGSALSTRALSPACTLYGVEPEAGNDGQQSFRSGKIVHIDTPKTIADGAQTQHLGNYTFEIIRRDVNDVLTASDAQLKDCMRFFASRMKLVVEPTGCLGLAAAQSMKEQLRNKRVGVIISGGNVDLDRFSALLQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GT06</accession>
    <name>A0A2S9GT06_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyl transferases group 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4424</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000034">
        <property type="protein sequence ID" value="PRC90843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90843">
        <property type="protein sequence ID" value="PRC90843"/>
        <property type="gene ID" value="S2091_4424"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="198"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="551" mass="60834" checksum="9780986FA9E626B2" modified="2018-07-18" version="1">MSQPNATLLYQAEGYTTNGDKLMGRQAAGEGLLRAAAQSGAVQLSCHTDNPASARHFVEQLAQHGYSGKTNWVPTEHPAGLADSGCLYLPGPNLMDFAWRRAPLGDRTYSLCGITHTTASHIAMTAITDLLIAPVRSWDALICTSTAVRDTVRVLLENQAAYLCERLGANRFELPQLPVIPLGVHTADYVFTENERAAARADLGIGQDDIVMLFVGRLSFHAKAHPQQMFTALERAAKGRRVHLIQCGWFPNAPIEAAFNDAAQVLCPSIFLHYIDGRQAAGRRQAWAAAHIFISLSDNIQETFGLTPIEAMASGIPVIVSDWDGYKDTVRDQIDGFRIPTLTPPVPLGADLAQRYENGTDTYDVYCGLASQLTALDPVALEMACSKLIVDAELRQQMGAAGSARAREVYEWKIIYQRYQTLWAELAEQRRADPNLHGPLKAFHRPDRLDPFAAFASYPTSQLSGKHVVSLRDEAAQLSSRRHMAMNSFAQRVQLSAEECEMIFTRLKQHGTQTVSEVIACFKIERRPYIVRGLVWLAKMEAVHIFVSSNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GT41</accession>
    <name>A0A2S9GT41_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4382</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000033">
        <property type="protein sequence ID" value="PRC90889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90889">
        <property type="protein sequence ID" value="PRC90889"/>
        <property type="gene ID" value="S2091_4382"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="36"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="95"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="190" mass="22186" checksum="1120F2D1D8937FB9" modified="2018-07-18" version="1">MDSFYFYLILSGAIGPLVIILITYNFAGWNWKKKPWIPFVLGLIFLSITFATNYFFSSTSEELNSTLKNITSPSVYLFLQLNAKADNVIARMYELINIPLGVSLIAAALIYKADLEFDRRLKQYNRGLEDISKSEDTLTVDIKLFEERLNNGDRGADFLEAYQRIKESRLHIKMLRRMLQRKFDDFIEER</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTC4</accession>
    <name>A0A2S9GTC4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_4265</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000031">
        <property type="protein sequence ID" value="PRC90969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90969">
        <property type="protein sequence ID" value="PRC90969"/>
        <property type="gene ID" value="S2091_4265"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="32"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="69"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC90969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="136" mass="15439" checksum="B106B56E5D88273E" modified="2018-07-18" version="1">MISEDKNKILTSKPEEKLEILFDDISRKNKKIFIFSIVLLVIMITVAGAGLYRGFQEVNQKYSALNMQIASEVVKLKELNERADKLASQVVDDEADEKIHSKFVYDNLGPIVNDQAKRIEAIEKKINSRSQNGTPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTC7</accession>
    <name>A0A2S9GTC7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4266</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000031">
        <property type="protein sequence ID" value="PRC90970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90970">
        <property type="protein sequence ID" value="PRC90970"/>
        <property type="gene ID" value="S2091_4266"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="17"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="109" mass="12056" checksum="16A8367B0EFA5D91" modified="2018-07-18" version="1">MASLDVHISNIKQRSTICLLIGACFLVLLFFALLYIIIVPIDSMLLVERIGGLIILIGALITCSFYFLQCANACELTLGYIALGNERKVASTMDKSHCLKVFVANLRHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTF6</accession>
    <name>A0A2S9GTF6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phage tail protein I</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4272</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000031">
        <property type="protein sequence ID" value="PRC90976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90976">
        <property type="protein sequence ID" value="PRC90976"/>
        <property type="gene ID" value="S2091_4272"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006521">
        <property type="entry name" value="Tail_protein_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09684">
        <property type="entry name" value="Tail_P2_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01634">
        <property type="entry name" value="tail_P2_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC90976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="169" mass="19040" checksum="8F495738EB87D85D" modified="2018-07-18" version="1">MMTRSLLPPNTSPLERALEQSTARLGAVPFRLRDNWNPQTCPITLLPWLAWAVGVEEWDSTWPEQLQRDVVASTRAIRQQKGTPAAVKRALSAVGHPNAELIERSNSEWATFKVILTRPVSHVQAQLIRQRIENVKRVCCHLTALDFTSNPIKHNGTIKRDGTYSRGVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTM8</accession>
    <name>A0A2S9GTM8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4249</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000030">
        <property type="protein sequence ID" value="PRC91061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91061">
        <property type="protein sequence ID" value="PRC91061"/>
        <property type="gene ID" value="S2091_4249"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036629">
        <property type="entry name" value="YjbJ_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69047">
        <property type="entry name" value="SSF69047"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="61" mass="6996" checksum="0D235C336FF99931" modified="2018-07-18" version="1">MNRKQIRGTIRGLAGKLEEETGKFLGNWNLRRSGITKRISGNMERRAGDAVEMIKIMLKQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTW6</accession>
    <name>A0A2S9GTW6_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PSII_BNR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_4150</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000028">
        <property type="protein sequence ID" value="PRC91149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91149">
        <property type="protein sequence ID" value="PRC91149"/>
        <property type="gene ID" value="S2091_4150"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028203">
        <property type="entry name" value="PSII_CF48-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036278">
        <property type="entry name" value="Sialidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14870">
        <property type="entry name" value="PSII_BNR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50939">
        <property type="entry name" value="SSF50939"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015647436" description="PSII_BNR domain-containing protein" evidence="1">
        <location>
            <begin position="31"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="domain" description="PSII_BNR" evidence="2">
        <location>
            <begin position="185"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="398" mass="41812" checksum="9B87F12BEA26DA83" modified="2018-07-18" version="1">MNAIMRRQSRAVLLAVGMLLAVESVSAAHAAPDPLEHPAATSDRAARAMLLSVTTAGKRLVAVGEHGVIVYSDTQGKNWVQAKVPVSVSLTVVFFSDAKNGWAVGHDGVVLRSQDAGQHWEKRFDGNQANALMLAEAEKKLTSIRGELESKPGDADKATSPALEAAQNTLADIQAGAKFGPSRPLLGVWFKNADEGYVVGAYGQFFHTLDGGLHWESLANRINNPDGLHYNAISATPSGALLISGEGGKIYRSENQGESWQTLDSGYKGQLYGALGITHAGSEEQLLAFGFGGHILLSNADKPAGGWQELAIITNKNLIGGSQTSDGSVWLVAQDGSVLRSNEHAQHFTIVQQGTGLLIAGSAVLKEEAGYAEVAVAGMGGVHLISIDSGINMSGKLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GU00</accession>
    <name>A0A2S9GU00_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_4079</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000027">
        <property type="protein sequence ID" value="PRC91184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91184">
        <property type="protein sequence ID" value="PRC91184"/>
        <property type="gene ID" value="S2091_4079"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="3">
        <location>
            <begin position="8"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="4">
        <location>
            <begin position="132"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="2">
        <location>
            <begin position="132"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC91184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="237" mass="26789" checksum="A2AD3EEF7E32EB25" modified="2018-07-18" version="1">MTNETTINLVLIEDEKQIRRFLSAALINEGINVHEAETGKQGLIECATRKPDIIIVDLGLPDISGIELIREVRSWSEVPIIVLSARTQEHEKVDALDAGADDYLSKPFGTAELIARIRAHLRRRQPSATSNDHLFQFGDVTVDFSLRTVTKNEEAIHLSPIEYRLLSVLARNAGKVLTHRQLLNDVWGPNHSESNHYLRIYMANLRQKLEQAPAQPKHFLTETGVGYRLVIQDSRKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GU63</accession>
    <name>A0A2S9GU63_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF1854 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4034</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000026">
        <property type="protein sequence ID" value="PRC91249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91249">
        <property type="protein sequence ID" value="PRC91249"/>
        <property type="gene ID" value="S2091_4034"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015005">
        <property type="entry name" value="DUF1854"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08909">
        <property type="entry name" value="DUF1854"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF1854" evidence="1">
        <location>
            <begin position="25"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="154" mass="17391" checksum="96881CCF19A2B128" modified="2018-07-18" version="1">MQTSNFELSRNAFGKLTLTTGEEVHEGVTPVRAFPIQTPNECIALVSTDGREVAWIERLEDVSLQVRDLVLNELAGREFVPEILQIIGVSSFSTPCTWTVATDRGETNFVLRVEEDIRRIGDSLLVTDNHGINFLIRQPTKLDKHGRKILDRFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GU73</accession>
    <name>A0A2S9GU73_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_4045</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000026">
        <property type="protein sequence ID" value="PRC91260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91260">
        <property type="protein sequence ID" value="PRC91260"/>
        <property type="gene ID" value="S2091_4045"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="11"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="308" mass="34323" checksum="73912A22595B5FDF" modified="2018-07-18" version="1">MNKSKKLNIKVSLEALTVLDAIDHHGSFSAAAEILHRVPSTLTYTVQKLEQQLGIVIFDRTGHRSQLTASGKLLLREGRYLLDAAHRLEQRVCQQADGWENELRITLGGITPIEPLIPLIAEFDQLKSGTTLIFKREIFKGIWDALVNDRADLVVGAYVRHAPEECFLREIGSVEMVLVAAPHHPLAQEKTPLSNEQIRQHRAIAVADTSRSSTAYSAAGVLTGQDVLFVHSNSAKMKLIQANLGIGFLPRSYVQEHLDDGQLIELATQQAPLRSPSCFAWRNPKPGKALQWFINRLEQAVAENHLKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GU79</accession>
    <name>A0A2S9GU79_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4049</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000026">
        <property type="protein sequence ID" value="PRC91264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91264">
        <property type="protein sequence ID" value="PRC91264"/>
        <property type="gene ID" value="S2091_4049"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="62"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="100"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="139"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="178" mass="19993" checksum="13C7210E13295A34" modified="2018-07-18" version="1">MTNNPQTLIFLAFIPLILWRMYSRIRRMVGRQVSKPWRQWLTVCSFPLLVLLIGAVSFSQPYALLALFGGLALGIAFGVIGHRLTKFEQSTEGMFYTPNAHLGIALSLLLIGRLMYRFIETGLPGSATAVPQNTLPTPLTLALFGMLAGYYVTYAIGLILWRRNAERNKLPENNLETF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GU82</accession>
    <name>A0A2S9GU82_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 10">3,4-dihydroxy-2-butanone 4-phosphate synthase</fullName>
            <shortName evidence="10">DHBP synthase</shortName>
            <ecNumber evidence="6 10">4.1.99.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">ribB</name>
        <name evidence="12" type="ORF">S2091_4111</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 10">Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>D-ribulose 5-phosphate = (2S)-2-hydroxy-3-oxobutyl phosphate + formate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18457"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:58121"/>
            <dbReference type="ChEBI" id="CHEBI:58830"/>
            <dbReference type="EC" id="4.1.99.12"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="10">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="10">Binds 2 divalent metal cations per subunit. Magnesium or manganese.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 10">Cofactor biosynthesis; riboflavin biosynthesis; 2-hydroxy-3-oxobutyl phosphate from D-ribulose 5-phosphate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the DHBP synthase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">In the C-terminal section; belongs to the GTP cyclohydrolase II family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">In the N-terminal section; belongs to the DHBP synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.99.12" evidence="6 10"/>
    <dbReference type="EMBL" id="PUGF01000027">
        <property type="protein sequence ID" value="PRC91216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91216">
        <property type="protein sequence ID" value="PRC91216"/>
        <property type="gene ID" value="S2091_4111"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00275">
        <property type="reaction ID" value="UER00399"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008686">
        <property type="term" value="F:3,4-dihydroxy-2-butanone-4-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10990">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00180">
        <property type="entry name" value="RibB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017945">
        <property type="entry name" value="DHBP_synth_RibB-like_a/b_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000422">
        <property type="entry name" value="DHBP_synthase_RibB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032677">
        <property type="entry name" value="GTP_cyclohydro_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036144">
        <property type="entry name" value="RibA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00926">
        <property type="entry name" value="DHBP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00925">
        <property type="entry name" value="GTP_cyclohydro2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142695">
        <property type="entry name" value="SSF142695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55821">
        <property type="entry name" value="SSF55821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00506">
        <property type="entry name" value="ribB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0456">Lyase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="10" id="KW-0464">Manganese</keyword>
    <keyword evidence="9 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 10" id="KW-0686">Riboflavin biosynthesis</keyword>
    <feature type="domain" description="GTP_cyclohydro2" evidence="11">
        <location>
            <begin position="208"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="region of interest" description="D-ribulose 5-phosphate binding" evidence="10">
        <location>
            <begin position="27"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="D-ribulose 5-phosphate binding" evidence="10">
        <location>
            <begin position="140"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="28"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="32"/>
        </location>
        <ligand>
            <name>D-ribulose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58121"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="143"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="site" description="Essential for catalytic activity" evidence="10">
        <location>
            <position position="126"/>
        </location>
    </feature>
    <feature type="site" description="Essential for catalytic activity" evidence="10">
        <location>
            <position position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00008976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00018836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PRC91216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="370" mass="39727" checksum="B2A30FA5C5656BC8" modified="2018-07-18" version="1">MSISTTLEIVAELRAGRMVILVDEEDRENEGDLVMAAEFVTTEAINFMTKYGRGLVCLTLTAERCDQLQLPMMTTRNGTAYGTNFTVSIEAAEGVTTGISAADRAKTIQVAVDPMSDAADIVQPGHIFPLRAQKGGVLMRAGHTEAGCDFAELAGLTPAAVICEIMNDDGSMARLPDLIEFAKQHDLKIGTIADLIHYRSLTESFVERVAERSMVTAHGTFNAIAYRDKPSGSAHLALVHGDVSADQVALVRVHQPVSVLDLLECSVTTHSWNLASAMQAIQASPNGVLVLLNCEESAEQMFAQFTALTSPKAKPQGRAASMDLRTYGIGAQILKDVGVGKMQLLASPRKMPSMTGFNLEVVGYQEKPAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUI4</accession>
    <name>A0A2S9GUI4_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">Biotin carboxyl carrier protein of acetyl-CoA carboxylase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_3908</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 5">This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 5">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000024">
        <property type="protein sequence ID" value="PRC91363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91363">
        <property type="protein sequence ID" value="PRC91363"/>
        <property type="gene ID" value="S2091_3908"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00094"/>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009317">
        <property type="term" value="C:acetyl-CoA carboxylase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003989">
        <property type="term" value="F:acetyl-CoA carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001249">
        <property type="entry name" value="AcCoA_biotinCC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001882">
        <property type="entry name" value="Biotin_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01071">
        <property type="entry name" value="ACOABIOTINCC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="SSF51230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00531">
        <property type="entry name" value="BCCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00188">
        <property type="entry name" value="BIOTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0092">Biotin</keyword>
    <keyword evidence="5" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="5" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="6">
        <location>
            <begin position="71"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU364072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC91363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="153" mass="16340" checksum="A3160986FD0AB523" modified="2018-07-18" version="1">MDLRKLKTLIDLVAESDISELEVTEGEGKVRIVKASAQQPQQVMYMPQNMQQGHYAAPAPVTTATAAAAPVAEVPAGHIVKSPMVGTFYRSSAPGSPSFVEVGATIKEGDTLCIIEAMKLLNEIESDFSGVVKQILVENGQPVEFGQPLFVIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUL1</accession>
    <name>A0A2S9GUL1_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Cell division protein ZapD</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Z ring-associated protein D</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">zapD</name>
        <name evidence="6" type="ORF">S2091_3944</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Interacts with FtsZ.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="5">Localizes to mid-cell in an FtsZ-dependent manner.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the ZapD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000024">
        <property type="protein sequence ID" value="PRC91399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91399">
        <property type="protein sequence ID" value="PRC91399"/>
        <property type="gene ID" value="S2091_3944"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000917">
        <property type="term" value="P:division septum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043093">
        <property type="term" value="P:FtsZ-dependent cytokinesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01092">
        <property type="entry name" value="ZapD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009777">
        <property type="entry name" value="ZapD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027462">
        <property type="entry name" value="ZapD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036268">
        <property type="entry name" value="ZapD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39455">
        <property type="entry name" value="PTHR39455"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07072">
        <property type="entry name" value="ZapD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160950">
        <property type="entry name" value="SSF160950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2 5" id="KW-0132">Cell division</keyword>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0717">Septation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01092"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC91399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="251" mass="29006" checksum="DBCA19F6924FB9C1" modified="2018-07-18" version="1">MIVYEYPFNERIRTLLRLEDLYEKFSFFLQQDHPYQHHVALSLIFEMLEVAGRADLKSDLLQELERQKQTLLGFRSNPNVATDMLNAIIEDINRINAALMACQGKSGQNIRENEWLMSIRGRTIIPGGACEFDLPSYYAWQNNSAEQRRADIAHWFAPLVPLFEAISMALRLLRESGNTTKMLAQAGSYQQMLQGKVYQMIRLRLDANLGAIPEISANKYMLWVRFMSQDGTLKPRAFESEVPFELTLCNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUN0</accession>
    <name>A0A2S9GUN0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">GGDEF: diguanylate cyclase (GGDEF) domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_3834</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000023">
        <property type="protein sequence ID" value="PRC91419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91419">
        <property type="protein sequence ID" value="PRC91419"/>
        <property type="gene ID" value="S2091_3834"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01948">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001633">
        <property type="entry name" value="EAL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035919">
        <property type="entry name" value="EAL_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013656">
        <property type="entry name" value="PAS_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00563">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08448">
        <property type="entry name" value="PAS_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00052">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141868">
        <property type="entry name" value="SSF141868"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50883">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="4"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="3">
        <location>
            <begin position="134"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="4">
        <location>
            <begin position="212"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="6">
        <location>
            <begin position="296"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="domain" description="EAL" evidence="5">
        <location>
            <begin position="438"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC91419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="694" mass="76508" checksum="839D45BE1FA7F845" modified="2018-07-18" version="1">MKNRILILTYNSIDANILKSALLNTRDGPFYTECLSRLDAGLERLSLGGIDIVLVDLSLADSSGINTFNQLFNRIPHTPILILSAYEEEPLAIEAVQLGAQGYLSKGFFASSLIPQSLRSVIQRKNVEEALYKERSRAEITLNSISDAVICTDQLGNIDYMNVSAEKLTGWSIDEANGHPIADVFKLINGVTREPERSTVALVLQKNESRDLPPNTVLIKKDGSEASIEDTASPIHNRSGQLTGVAIVFHDVSHTQALSNKMEHLAQHDFLTNLPNRILLNDRIAQAIILAKRNHKQLALLFLDLDNFKHINDSLGHAAGDKLLQSVAQRLRDCIRGSDTVSRQGGDEFVLLLVGGEFDTDAAMIADKVRNALAAPHSIDGSDLYITTSIGISIYPADGKDADALLKSADTAMYYAKGKGRNNYQFFRSEMNIRAVERQFVEANLRSALEKREFILHYQPKINLSTGKISGAEALLRWKRPSSEMILPDRFIRIAEDCGLIIPIGRWVLRDACTQAKKWIEAGLAPVSIAVNISALEFRQVDFLESVRSVLNDTGLDVHCLQLEITENVLMDNAESSAFILQELKNIGVQLAVDDFGTGYSSLSYLNLFPLDVIKIDQSFVDGIGNSKDNGIIVGAVIGMGNSLKLKVVAEGIENLEQLNFLKGLHCEEGQGFYFSKPISSESFVEMLASERSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUR3</accession>
    <name>A0A2S9GUR3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3853</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000023">
        <property type="protein sequence ID" value="PRC91438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91438">
        <property type="protein sequence ID" value="PRC91438"/>
        <property type="gene ID" value="S2091_3853"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="66" mass="7265" checksum="6465529ECE392E86" modified="2018-07-18" version="1">MATTSFTIDTKLDQTLEDLKKHFGASSKAEVLRKAIALLNVVSKNESSDGSVTIRCNDQDIKVILR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUY0</accession>
    <name>A0A2S9GUY0_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein-glutamate O-methyltransferase</fullName>
            <ecNumber evidence="2">2.1.1.80</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">S2091_3871</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>L-glutamyl-[protein] + S-adenosyl-L-methionine = [protein]-L-glutamate 5-O-methyl ester + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:24452"/>
            <dbReference type="Rhea" id="RHEA-COMP:10208"/>
            <dbReference type="Rhea" id="RHEA-COMP:10311"/>
            <dbReference type="ChEBI" id="CHEBI:29973"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:82795"/>
            <dbReference type="EC" id="2.1.1.80"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.80" evidence="2"/>
    <dbReference type="EMBL" id="PUGF01000023">
        <property type="protein sequence ID" value="PRC91456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91456">
        <property type="protein sequence ID" value="PRC91456"/>
        <property type="gene ID" value="S2091_3871"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000156">
        <property type="term" value="F:phosphorelay response regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008984">
        <property type="term" value="F:protein-glutamate methylesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008983">
        <property type="term" value="F:protein-glutamate O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.155.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035909">
        <property type="entry name" value="CheB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022642">
        <property type="entry name" value="CheR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000780">
        <property type="entry name" value="CheR_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022641">
        <property type="entry name" value="CheR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036804">
        <property type="entry name" value="CheR_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013767">
        <property type="entry name" value="PAS_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000673">
        <property type="entry name" value="Sig_transdc_resp-reg_Me-estase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01339">
        <property type="entry name" value="CheB_methylest"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01739">
        <property type="entry name" value="CheR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03705">
        <property type="entry name" value="CheR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00989">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00996">
        <property type="entry name" value="CHERMTFRASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00138">
        <property type="entry name" value="MeTrc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52738">
        <property type="entry name" value="SSF52738"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50122">
        <property type="entry name" value="CHEB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50123">
        <property type="entry name" value="CHER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0145">Chemotaxis</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="CheB-type methylesterase" evidence="10">
        <location>
            <begin position="34"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="domain" description="CheR-type methyltransferase" evidence="11">
        <location>
            <begin position="229"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="9">
        <location>
            <begin position="894"/>
            <end position="964"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="706"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="43"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="72"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PRC91456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="1012" mass="112149" checksum="E60C9A7097E8524E" modified="2018-07-18" version="1">MPSKRITKKPATEPAIVPFILPGTIIPEKNYSDAFPIVGIGASAGGLAAFEAFFSGLPSDIEPGMAFVLVQHLAPDHKSLLTELIRRCTRMQVFEVEDGMVVQRNCVYIIPPNHDMAFLNGTLHLLEPSAPRGQRLPIDFFFRSLAQDQCECAIGIVLSGTGSDGTLGVRAIKGEGGMVIVQVPETSDFDGMPRSVIATGLADYVLPPAEMAAQLIAYAAHAYGKLPRSAAVDMTKSESALKKIFILLRSQTGHDFSNYKPSTINRRIDRRMAVHQIAEIGSYMKYLQQTPSEAEALFRDLLIGVTNFFRDPEVFELLEKDIIPKLFASKPAGGVVRVWSTGCSTGEEAYSIAILLQERMETLKQNYTVQVFATDIDSRAIAIARAGLYPASIAADITPERLARFFSTEPDGCTFRIHKSIRDMLVFSEQDVIKDPPFSKLDLISCRNLLIYLGMQLQKRLIPLFHYALKPDGILLLGTSEGVGDFTGLFPVLDRKSKLFQRKENYQVRPSMSLGRTLPRSLPLDHTTTAGSKKMTFPVKLQLRELTEQALLQQLAASSALVNWHGDILYLHGRTGMYLELTPGEVGISNILKMAREGLRRDLTMALHKAVGSKGVVRCSGLRVQTNGHFTLVNLTVSPVLAGPLATPESYLYLVILEEVSTIATEILQPTALLAEPKEINVELDAESRIAILKQELRAKDEYLQSTHEELESSNEELKSSNEEMQSVNEELQSTNEELETSKEELQSVNEELATVNNELQTKVIDLSRANNDMNNLLAGTGIGTVFVDYQLRILRFTPAASTIINLIPSDVGRPVAHIVSNLLDYDSLVVDTQEVLNTLIFKEVAVQTVEGLWYTMRIQPYRTLDNVIEGAVISFIDITETVRTRNDLHKANKLMRLAVVVRDAHDAITMQNLQGSILAWNPGAVRIYGWSESEALAMNVRDRIPLEEREEALVRLQQLSQAEILEPYSTQRITKQGSVIKVSITSTALLNEVGEVYAIATTERAIREITQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GV05</accession>
    <name>A0A2S9GV05_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Uncharacterized protein YtcA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">S2091_3673</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the YtcA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000021">
        <property type="protein sequence ID" value="PRC91557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91557">
        <property type="protein sequence ID" value="PRC91557"/>
        <property type="gene ID" value="S2091_3673"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031381">
        <property type="entry name" value="YtcA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17090">
        <property type="entry name" value="Ytca"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="5 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="37"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="66"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC91557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="89" mass="9651" checksum="EADDB9FCA5C92DA8" modified="2018-07-18" version="1">MTKRFLVVVFISNLLLSGCARSPSINVLGAYFPDWMFCFIGGILLAMLTHAGLVGAGVIKKINSPVLLLSYSALTAILAMLGWLLFFQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GV16</accession>
    <name>A0A2S9GV16_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Geranylgeranyl pyrophosphate synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3669</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the FPP/GGPP synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000021">
        <property type="protein sequence ID" value="PRC91553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91553">
        <property type="protein sequence ID" value="PRC91553"/>
        <property type="gene ID" value="S2091_3669"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008299">
        <property type="term" value="P:isoprenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00685">
        <property type="entry name" value="Trans_IPPS_HT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000092">
        <property type="entry name" value="Polyprenyl_synt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033749">
        <property type="entry name" value="Polyprenyl_synt_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00348">
        <property type="entry name" value="polyprenyl_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="SSF48576"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00723">
        <property type="entry name" value="POLYPRENYL_SYNTHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00444">
        <property type="entry name" value="POLYPRENYL_SYNTHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU004466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="310" mass="33434" checksum="DA589968418FDCD6" modified="2018-07-18" version="1">MMPELNILMTTSSTLSDWMKQSQAHIEAALTDFLPSPQQTPTHLHEAMRYAVLDGGKRVRPLLVYAAGQLFDADYAELTRAACALEMIHAYSLVHDDMPCMDDDALRRGKPTVHVKFGEATALLVGDALQAQAFLILAQGKTAPARQLEMLRILAHSSGSLGMCGGQAIDLASVGCNLSRDQLEQMHQLKTGALLRASVLLGALCGQELNEIDQAALHRYSHSIGLAFQVVDDILDATSDSASLGKTAGKDAANNKPTYVSILGLAASQTLAENLRIEAHNALHSFTATMQNSRTQRLSQLADFIVQRSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GV94</accession>
    <name>A0A2S9GV94_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Glycerol kinase</fullName>
            <ecNumber evidence="5">2.7.1.30</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">ATP:glycerol 3-phosphotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Glycerokinase</fullName>
            <shortName evidence="5">GK</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">glpK</name>
        <name evidence="9" type="ORF">S2091_3590</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>ATP + glycerol = ADP + H(+) + sn-glycerol 3-phosphate</text>
            <dbReference type="Rhea" id="RHEA:21644"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17754"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57597"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.30"/>
        </reaction>
    </comment>
    <comment type="activity regulation">
        <text evidence="5">Inhibited by fructose 1,6-bisphosphate (FBP).</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Polyol metabolism; glycerol degradation via glycerol kinase pathway; sn-glycerol 3-phosphate from glycerol: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the FGGY kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.30" evidence="5"/>
    <dbReference type="EMBL" id="PUGF01000020">
        <property type="protein sequence ID" value="PRC91652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91652">
        <property type="protein sequence ID" value="PRC91652"/>
        <property type="gene ID" value="S2091_3590"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00618">
        <property type="reaction ID" value="UER00672"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004370">
        <property type="term" value="F:glycerol kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019563">
        <property type="term" value="P:glycerol catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006072">
        <property type="term" value="P:glycerol-3-phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00186">
        <property type="entry name" value="Glycerol_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000577">
        <property type="entry name" value="Carb_kinase_FGGY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018485">
        <property type="entry name" value="Carb_kinase_FGGY_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018483">
        <property type="entry name" value="Carb_kinase_FGGY_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018484">
        <property type="entry name" value="Carb_kinase_FGGY_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005999">
        <property type="entry name" value="Glycerol_kin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02782">
        <property type="entry name" value="FGGY_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00370">
        <property type="entry name" value="FGGY_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000538">
        <property type="entry name" value="GlpK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01311">
        <property type="entry name" value="glycerol_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00933">
        <property type="entry name" value="FGGY_KINASES_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00445">
        <property type="entry name" value="FGGY_KINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 5" id="KW-0319">Glycerol metabolism</keyword>
    <keyword evidence="5 6 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="FGGY_N" evidence="7">
        <location>
            <begin position="6"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="domain" description="FGGY_C" evidence="8">
        <location>
            <begin position="260"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="83"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="244"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="13"/>
            <end position="15"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="13"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="17"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="135"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="266"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="309"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="313"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="410"/>
            <end position="414"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC91652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="500" mass="54550" checksum="D7D45E644D4C642B" modified="2018-07-18" version="1">MENKFILALDQGTTSSRAALFDHAGNIISVAQKEFQQIYPHPGWVEHDPQEIWSTQAGVAAEAVTKMGLNGSSIAAIGITNQRETTIVWERATGRPIYNAIVWQDRRTAAYCDELKSRGLEKIVRAKTGLPIDSYFSATKINWILNNVAGARERAERGELAFGTVDTWLIWNFTQHELHVTDVTNASRTMLFNIHTLDWDEELLAAMDIPRNMLPQVRSSSEIVGHTKSTVFATPIPIAGIAGDQHAALFGQMCTRAGMAKNTYGTGCFLVMNTGNKPVESKNNLITTIAWKIGDQVTYALEGSIFIGGAVVQWLRDGIGMIKSASEIEQLARTVPDSDGVFMVPAFAGLGAPHWNPHARGSIFGVTRGTTSAHLARAALEAIALQSYDVLKAMEADLGEKIAELRVDGGAVTNDLLMQFQADLLGVDVVRPKIIETTALGAAYLAGLAVNYWASIDEIQGQWKQDQRFSPSMDAAQVSNYKKGWQRAVTASIAWADSND</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVM3</accession>
    <name>A0A2S9GVM3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Bacterial regulatory protein, tetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3519</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000019">
        <property type="protein sequence ID" value="PRC91764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91764">
        <property type="protein sequence ID" value="PRC91764"/>
        <property type="gene ID" value="S2091_3519"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="5"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="28"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="183" mass="20679" checksum="3522860049483371" modified="2018-07-18" version="1">MSQPSNPRERILLTAHDLFYRDGIRATGIDRVIAESGVAKATFYKYFPSKNDLIYEFLEYRHQYWMTWFVDALQRHGDEPKALTLAMAEWFANAGFRGCAFINSVAELGGTLPEVLEISRRHKQEMTETISKLLPPSRHRKQDAAALSLAVDGAIIRAQCDPEPDAALASLELIRKLLMATPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVP1</accession>
    <name>A0A2S9GVP1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3548</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000019">
        <property type="protein sequence ID" value="PRC91793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91793">
        <property type="protein sequence ID" value="PRC91793"/>
        <property type="gene ID" value="S2091_3548"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015597739" evidence="1">
        <location>
            <begin position="23"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="157" mass="17644" checksum="EA6DE453E6F16264" modified="2018-07-18" version="1">MRKINLFTLMLSLLLFPIISSAQSSFENELKKVSNGKKQKLFIEKIAQQAKEKDTASILAEMDPSTLKAAGEANIVHELETKVFPFFAPYIKLNNYDQITNATLPDGRSGLWHYTYITSAEEKMLPFRIAVIDTGDGPKILDIVVNECVKGRHPICK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVQ3</accession>
    <name>A0A2S9GVQ3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3558</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000019">
        <property type="protein sequence ID" value="PRC91803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91803">
        <property type="protein sequence ID" value="PRC91803"/>
        <property type="gene ID" value="S2091_3558"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015603913" evidence="1">
        <location>
            <begin position="24"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="123" mass="13385" checksum="B3FDB5A6B1437F2E" modified="2018-07-18" version="1">MKKLARLFLLCMIMIANPLQGMAATAMTCCTNQHQHQHAMAEQHERHQHDGCQKSLDVSRSLGHLSKSQCSTCSSCVSCHFAALPIMAVPSATIFNPSSDKIDSILSFQPSHISAAPERPPKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GW03</accession>
    <name>A0A2S9GW03_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="8 10">Adenylosuccinate synthetase</fullName>
            <shortName evidence="8">AMPSase</shortName>
            <shortName evidence="8">AdSS</shortName>
            <ecNumber evidence="8 10">6.3.4.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">IMP--aspartate ligase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">purA</name>
        <name evidence="11" type="ORF">S2091_3461</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 10">
            <text>GTP + IMP + L-aspartate = GDP + 2 H(+) + N(6)-(1,2-dicarboxyethyl)-AMP + phosphate</text>
            <dbReference type="Rhea" id="RHEA:15753"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57567"/>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="EC" id="6.3.4.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="8">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="8 10">Purine metabolism; AMP biosynthesis via de novo pathway; AMP from IMP: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1 8">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8 10">Belongs to the adenylosuccinate synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.4" evidence="8 10"/>
    <dbReference type="EMBL" id="PUGF01000018">
        <property type="protein sequence ID" value="PRC91905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91905">
        <property type="protein sequence ID" value="PRC91905"/>
        <property type="gene ID" value="S2091_3461"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00075">
        <property type="reaction ID" value="UER00335"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004019">
        <property type="term" value="F:adenylosuccinate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044208">
        <property type="term" value="P:'de novo' AMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd03108">
        <property type="entry name" value="AdSS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.300.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.170.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00011">
        <property type="entry name" value="Adenylosucc_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018220">
        <property type="entry name" value="Adenylosuccin_syn_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033128">
        <property type="entry name" value="Adenylosuccin_syn_Lys_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042109">
        <property type="entry name" value="Adenylosuccinate_synth_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042110">
        <property type="entry name" value="Adenylosuccinate_synth_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042111">
        <property type="entry name" value="Adenylosuccinate_synth_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001114">
        <property type="entry name" value="Adenylosuccinate_synthetase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11846">
        <property type="entry name" value="PTHR11846"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00709">
        <property type="entry name" value="Adenylsucc_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00788">
        <property type="entry name" value="Adenylsucc_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00184">
        <property type="entry name" value="purA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01266">
        <property type="entry name" value="ADENYLOSUCCIN_SYN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00513">
        <property type="entry name" value="ADENYLOSUCCIN_SYN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 8 10" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2 8 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="6 8 10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 8 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 8 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 8 10" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="IMP binding" evidence="8">
        <location>
            <begin position="19"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="IMP binding" evidence="8">
        <location>
            <begin position="44"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="8">
        <location>
            <begin position="307"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="19"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="8">
        <location>
            <position position="47"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="146"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="18"/>
            <end position="24"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="19"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="46"/>
            <end position="48"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="46"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="135"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="149"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="230"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="245"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="311"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="313"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="339"/>
            <end position="341"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="421"/>
            <end position="423"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC91905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="437" mass="46451" checksum="06AA728DAC9FE809" modified="2018-07-18" version="1">MSQINTAKNVVVIGTQWGDEGKGKIVDWLTDHAQGVVRFQGGHNAGHTLVIGGQKTALQLIPSGIMRAGVACYIGNGVVLSVPDLLREIDKLQANGVEVESRLKISEACPVILPYHTALDAAREAARGAAKIGTTGKGIGPAYEDKVARRAIRVADLLNPERFAEKLRENLDYHNFVLTQYLHAPAVDFQKTLDDTLAQVPRIAPMVADVSSALYAAYKGGARLLFEGAQGSLLDVDHGTYPFVTSSNCVAGNAAAGSGVGPSMLHYVLGITKAYTTRVGSGPFPSELTSENGVGKHLSSVGCEFGTVTGRARRCGWFDAALLKRSVQINGVSGMCLTKLDVLDGIDTLQICTGYTVDGKSADIFPSGAEEASRCVPVYESMPGWTESTVGAKSLDALPVNARNYIKRIEELVGVPIDMVSTGPDREETIVLRHPFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GW09</accession>
    <name>A0A2S9GW09_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">GTPase HflX</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">GTP-binding protein HflX</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">hflX</name>
        <name evidence="10" type="ORF">S2091_3465</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="5">Monomer. Associates with the 50S ribosomal subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="5">May associate with membranes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000018">
        <property type="protein sequence ID" value="PRC91909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91909">
        <property type="protein sequence ID" value="PRC91909"/>
        <property type="gene ID" value="S2091_3465"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01878">
        <property type="entry name" value="HflX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11060">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00900">
        <property type="entry name" value="GTPase_HflX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030394">
        <property type="entry name" value="G_HFLX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032305">
        <property type="entry name" value="GTP-bd_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016496">
        <property type="entry name" value="GTPase_HflX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025121">
        <property type="entry name" value="GTPase_HflX_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042108">
        <property type="entry name" value="GTPase_HflX_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10229">
        <property type="entry name" value="PTHR10229"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16360">
        <property type="entry name" value="GTP-bdg_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13167">
        <property type="entry name" value="GTP-bdg_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006809">
        <property type="entry name" value="GTP-binding_hflX_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03156">
        <property type="entry name" value="GTP_HflX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51705">
        <property type="entry name" value="G_HFLX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5 6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3 7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 5 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hflx-type G" evidence="9">
        <location>
            <begin position="183"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="149"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="189"/>
            <end position="196"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="196"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="214"/>
            <end position="218"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="216"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="236"/>
            <end position="239"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="302"/>
            <end position="305"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="327"/>
            <end position="329"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR006809-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR006809-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC91909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="365" mass="40206" checksum="80392E6B6C27839B" modified="2018-07-18" version="1">MDFGKSDFNSSLEELSLLALSAGAKPISTITCKRSSPDSALFVGSGKADEIAHAVLDHEIEIVIFNHALSPAQQRNLEKHLKIRVVDRTSLILDIFAQRAKSHEGKVQVELAQLQHLATRLVRGWTHLERQKGGIGLRGPGETQLETDRRLIGDRVKALKDKLAKLQRQRETQRRARGRSRVFSVSLVGYTNAGKSTLFNVLTKAGAYTADQLFATLDTTSRRVYLGDAGQIVVSDTVGFIRELPHQLVAAFRATLEETIHADLLLHVVDAASPARLDQILQVNQVLQEIGADHIPQLLVWNKIDVADLSAGIDRDEYDKIQRIFLSAKTGQGLTELRVALAEFAAQLGFGPPSVESTDHESHQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GW74</accession>
    <name>A0A2S9GW74_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3290</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000017">
        <property type="protein sequence ID" value="PRC91948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91948">
        <property type="protein sequence ID" value="PRC91948"/>
        <property type="gene ID" value="S2091_3290"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015643092" evidence="1">
        <location>
            <begin position="27"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="395" mass="42776" checksum="16D5D0506644A5B3" modified="2018-07-18" version="1">MQNKTLSKLGCLLFLIGMVNGTQVLAASCEDNFSSSGSFFTGSTFKTWAELPNSKFESAYKGAYMYTVKDGWKILQSNKEMGVISAAQAASYAKGKVIPLNIAVEKLGAGTKISLVYTTPAGAVSPEAAVKTHFCKTIEAAEAEQADTTAVAVNAPNASNTKPVANTKTMEGADDKAQANNIKTDEFIKGNKPCLGGICIGDDVASLSKITWAPMPSNFKNYHPSDVEVQNMMHGQKFVAGANSADILRGAMPYMAFSIFDSDAVPKLTELHGFCENMAGFLGSYKSDSGFDTYVVVNVLPDAYPSPRKLQVTSIRRNYPTIYTEDQVKELASQFKKRYASIPGEAYRATHTKPSEVEWSFQNRALIIGYSGGWMSSRIEQFKQYPGCGKALSID</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWK5</accession>
    <name>A0A2S9GWK5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3237</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000016">
        <property type="protein sequence ID" value="PRC92102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92102">
        <property type="protein sequence ID" value="PRC92102"/>
        <property type="gene ID" value="S2091_3237"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="33"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="69" mass="7722" checksum="EC543F4D56C7B213" modified="2018-07-18" version="1">MISEFQQLAKKVDQLATLTQTMRGENTDLRHKIAELTATNAALSSRIQEAHERVTALLEKLPSAEQESE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWN4</accession>
    <name>A0A2S9GWN4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">EAL domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_3045</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92129">
        <property type="protein sequence ID" value="PRC92129"/>
        <property type="gene ID" value="S2091_3045"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01948">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.270.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001633">
        <property type="entry name" value="EAL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035919">
        <property type="entry name" value="EAL_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032244">
        <property type="entry name" value="LapD_MoxY_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042461">
        <property type="entry name" value="LapD_MoxY_peri_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00563">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16448">
        <property type="entry name" value="LapD_MoxY_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00052">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141868">
        <property type="entry name" value="SSF141868"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50883">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="148"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="3">
        <location>
            <begin position="170"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="4">
        <location>
            <begin position="262"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="domain" description="EAL" evidence="2">
        <location>
            <begin position="401"/>
            <end position="637"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC92129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="637" mass="69312" checksum="E7AE3C1C06B33438" modified="2018-07-18" version="1">MSMYRQIWLSLILTALLSLAGGLFASTFSVRAYLEDQLRMKNTDNATSLALALSQRNIGTIEIKLAVTSLFDKGYYDLIRVVDASGREIISRKALTNSDDTPSWFMQSLPLTVVPGIAHFNNGWNQVGTITLVSNTRFAYKALWESTLALIGALVFTSLVGGWLGTLVLRRIKAPLNAVIAQAQAITAHHFITIPESTVPELRQLTSAMNSTVLLLKKMFADEAQRLELVRLEANSDSLTKLANRLSFMAQLQATLEMEDSYAGALVLVKIADLGAINKRLGRTETDNFLKSVAVTMSKAVAVVPNALVARLNGADFGLLLPLSEAHPITDQLLDALVLETSAYIQSGPVAFIGVGKFSYGVNLASLMMQVDAALAGAEAQGISCIRDAASLKSDDAPRSNEEWSKLIYHAIENQETKLGSFPLTDFAGKLLHSECPLRLRLAHEWLPAGSFLSVAERLGMSSTLDTIAITLGIDELNMNREIVGLAINLSARSLEDGTFCEYIRAMLLANPKAARRLWIEFPEYGAYAHFAAFNEFLNKMAGTGCRLGLEHFGRQFSKIGLLQDLKLDYLKVDVSFIRDINNNQGNQVFLKGLIGIGHNFGMQIFAEGVASPDELITLAQLGFDGATGPGVKVASM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWR2</accession>
    <name>A0A2S9GWR2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3081</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92165">
        <property type="protein sequence ID" value="PRC92165"/>
        <property type="gene ID" value="S2091_3081"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="183" mass="19733" checksum="9B8F08D3027109DE" modified="2018-07-18" version="1">MNKISLLLIAITLGINYHSTQAQTSPDALLDLSKDISIEPGEIPGFFSSPPGVNMVKNAVKNRDGSKTIKAGQQVPEANDLNRKVCESMGMKDITNENDFTLGAGAAYGGVCFSTEPPRNRSTRVQAIPGKGTGRVFIPIPENDLNKPQAPMPYSTRAPMQIIPYATTGSSTFNQMYYAHSLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GX28</accession>
    <name>A0A2S9GX28_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acetyltransferase (GNAT) domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2931</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92272">
        <property type="protein sequence ID" value="PRC92272"/>
        <property type="gene ID" value="S2091_2931"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13673">
        <property type="entry name" value="Acetyltransf_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="2"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="172" mass="18966" checksum="15371E693C5654DB" modified="2018-07-18" version="1">MTTIRLADLADASNLAALGIQVWLHTYATSGIHQAISDYVLAEFTAEKFQQLLIAPDHIVLIAEKNAHLVGYAVLKLDARCNDVSHTSTELVTLYVQEHFTRQNIGTALLSACADYAQQSTGSALLWLSVNQNNTRASTFYHQHGFRKYGVTYFEIGSERHANDILAKPSAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GX32</accession>
    <name>A0A2S9GX32_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aspartate/tyrosine/aromatic aminotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2920</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92261">
        <property type="protein sequence ID" value="PRC92261"/>
        <property type="gene ID" value="S2091_2920"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="1">
        <location>
            <begin position="34"/>
            <end position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="409" mass="45749" checksum="34C0E34194DC190C" modified="2018-07-18" version="1">MRLIQKSKKLDNICYEIRGPVPERARQLEEDGHKIIKLNIGNLAAFNFDPPDEIVRDMILNMPHAAGYTDSKGMFAPRKAIMHYAQSKHIQGVTIEDIYIGNGASELIVMGMSALLNDGDEVLVPAPDYPLWTAAVSLSGGTPVHYLCDETAEWMPDIEDIKRKITPQTRAIVVINPNNPTGTIYPVELLQQIVELARVHQLIIFADEIYDKMLYDEASHTSIASLADDVLFVTLNGLSKNYRSCGYRAGWMVVSGEKRHAKDYIEGLNMLASMRLCANTPGQFAIQTALGGYQSIQELVGHGGRLLKQRDLAYKLLTAIPGVTCVKPKAALYMFPKLDPLMYPIANDQEFAYQLLDQEKVLIVQGTGFNWGSHDHFRAVFLPNSDDLTDAIGRIARFLDGYRRRHSIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GX38</accession>
    <name>A0A2S9GX38_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Phenylalanine--tRNA ligase beta subunit</fullName>
            <ecNumber evidence="14">6.1.1.20</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Phenylalanyl-tRNA synthetase beta subunit</fullName>
            <shortName evidence="14">PheRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">pheT</name>
        <name evidence="19" type="ORF">S2091_2944</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 14">
            <text>ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + H(+) + L-phenylalanyl-tRNA(Phe)</text>
            <dbReference type="Rhea" id="RHEA:19413"/>
            <dbReference type="Rhea" id="RHEA-COMP:9668"/>
            <dbReference type="Rhea" id="RHEA-COMP:9699"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58095"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78531"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.20"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="14">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="14">Binds 2 magnesium ions per tetramer.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 14">Tetramer of two alpha and two beta subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 14">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.20" evidence="14"/>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92285">
        <property type="protein sequence ID" value="PRC92285"/>
        <property type="gene ID" value="S2091_2944"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004826">
        <property type="term" value="F:phenylalanine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006432">
        <property type="term" value="P:phenylalanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00769">
        <property type="entry name" value="PheRS_beta_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02796">
        <property type="entry name" value="tRNA_bind_bactPheRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00283">
        <property type="entry name" value="Phe_tRNA_synth_beta1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005146">
        <property type="entry name" value="B3/B4_tRNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005121">
        <property type="entry name" value="Fdx_antiC-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036690">
        <property type="entry name" value="Fdx_antiC-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045060">
        <property type="entry name" value="Phe-tRNA-ligase_IIc_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004532">
        <property type="entry name" value="Phe-tRNA-ligase_IIc_bsu_bact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020825">
        <property type="entry name" value="Phe-tRNA_synthase-like_B3/B4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041616">
        <property type="entry name" value="PheRS_beta_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002547">
        <property type="entry name" value="tRNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033714">
        <property type="entry name" value="tRNA_bind_bactPheRS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005147">
        <property type="entry name" value="tRNA_synthase_B5-dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10947">
        <property type="entry name" value="PTHR10947"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03483">
        <property type="entry name" value="B3_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03484">
        <property type="entry name" value="B5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03147">
        <property type="entry name" value="FDX-ACB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01588">
        <property type="entry name" value="tRNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17759">
        <property type="entry name" value="tRNA_synthFbeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00873">
        <property type="entry name" value="B3_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00874">
        <property type="entry name" value="B5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00896">
        <property type="entry name" value="FDX-ACB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54991">
        <property type="entry name" value="SSF54991"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00472">
        <property type="entry name" value="pheT_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51483">
        <property type="entry name" value="B5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51447">
        <property type="entry name" value="FDX_ACB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50886">
        <property type="entry name" value="TRBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13 14" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="9 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="14" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 14 19" id="KW-0436">Ligase</keyword>
    <keyword evidence="10 14" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12 14" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11 15" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5 15" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="TRNA-binding" evidence="16">
        <location>
            <begin position="39"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="domain" description="B5" evidence="18">
        <location>
            <begin position="407"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="domain" description="FDX-ACB" evidence="17">
        <location>
            <begin position="709"/>
            <end position="807"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="460"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="466"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="469"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="470"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="PRC92285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="808" mass="87958" checksum="1D9536A4B084BFCA" modified="2018-07-18" version="1">MQFSENWLRTMVNPSMGSDALAHLLTMSGLEVEDTETVAPPFSHVVVAQVVSLEKHPNADRLNVCKVDVGTGELLTIVCGAPNVRAGMKVACAKAGAMLPPGADGKPFEIKVGELRGVESQGMLCSARELKLSEENSGLMDLPEDAPIGASIRDFLDLDDLKFTIKLTPNKADCLSVLGVAREVSALTGTALHVPSATAVPVTLTEILPVKVSAPDLCGRFSGRVIRGVNAKAPTPDWMKQRLERAGQRPISALVDISNYVMLELGQPSHVFDLDKLSGGIEVRWGKAGESIKLLNGNTVNVDPWIGVISTTGEAPILESLAGIMGGDATSVTLDTQNIYLEAAFWWPSAIQGRARRFNFSTDAAHRFERGVDFASTVAHIERITGLIVTICGGSVGPVDDQIINLPTRPPVKLRTARAIKVIGVALSDVQIADIFQRLGLPFTQEPDGFLVTPPSYRFDIEIEEDLIEEVARVYGFENIPALPPVAASAMRILPENTRSLFKVRRQIADLDYQEVLNYSFVEAAWEQDFANNANPIKVQNPIASHMSVMRTNLIASLVANARYNLNRKVSRIRIFEIAPVYLRDETVLDGGLTVAGFNEPKKLAGLSYGSQAEEQWGQATRQVDFFDVKADIEALFAPKTLRFSKVDHPALHPGRSAQIECDGKVVGVLGELHPALQQKYDLPLAPVVFELDAVALQAVGVPAYQEIPKFQAVTRDLALLVNQTVAVQDVLDVFMQERRLNPACLCVQAIVLFDEYRGKGLQDNEKSLAFRCTLQDTQSTLQEELIEAAMAALLSAAQTRCDAKLRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GX58</accession>
    <name>A0A2S9GX58_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_2964</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92305">
        <property type="protein sequence ID" value="PRC92305"/>
        <property type="gene ID" value="S2091_2964"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004673">
        <property type="term" value="F:protein histidine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="189"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="5">
        <location>
            <begin position="280"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="216"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC92305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="514" mass="57507" checksum="44867F48B4FA83F3" modified="2018-07-18" version="1">MKLKTLGVVLIALLAGSSFVFTVALLIVENQFDAAQQSINSVYLKSVLPLQEIDANTKNLRFQLYASFMHNKQLDVSVLHDHPISIHFNIIEAEIKKNQMLWEELKTRPEIPETDLRELRGLYDTFYRDDITPAFTAAKNADWMGIVRPITSSLNNYVEFERVLQDKIASIQLSEQRRYENMRAWQRNFFNLLLVLVLMVLTVATMLAWRTISHHSALLQETNRSLAEANQGLEEKVSARTQALAIANDEMTKLVEHLQATQKQLVQAEKLVALGGLVSGVAHELNTPIGNGLLMATTLSDLASEFETSLGKGMARSTFVKHAAQIKDCCALIEGSLQKAANIIVSFKFIAMDQRNERRQRFELAELLNAILVERHPYFQKARCDVQMRLPEGLALDSYPDSLTMVFNILIDNALTHAFDENSPGSIEIVAREMDQNMVEITFSDDGAGMDPQVLQRIFEPFFTTQMGQGTNGLGMTIAYNIVTGILGGYISVKMASPRGTIVEIVVPKVVLSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GX63</accession>
    <name>A0A2S9GX63_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2973</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92314">
        <property type="protein sequence ID" value="PRC92314"/>
        <property type="gene ID" value="S2091_2973"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="697" mass="79622" checksum="3F9716180CA5723E" modified="2018-07-18" version="1">MAFNAPAPILGLSENSEFPEVIDDLSSLFSVTQPDSVDGIVFEILDKYAITLDTQSYPASLYAESLLYMVYWYHRLRDPIRKNGIEICIGKYLNVDPQSAVVNALLSDQELKIQAKQRIDQGVMVRKTIDVLVMRDGQSGREFLTLNRTFFPEGLSLPGGLLRDEDEQNEIGIPAHIFAALRVTGTKVFGSATLEYGISESDGRKYYFVRNEAGKVARIYMDRTISHGYRDHLKEIAVPSDPRHIVDTVGFLVEISDTEGVEGRWLPESMITTPNAKEGSFAFGHHKQIAAALIAKNFSKTQGISHHEWIRESVNNPLDVYRGLRVRFALNNDSLDTPIIELLPVVEHFRSQMMLPAIVGKCRDNAALASMRDQLLHKLHHVTIQNGPMCPYAPTLRILFEAVGFFDVVCRTEKNLSTHFQKKYWYRYEELMHRIPDVIIIPTFDNISATDLMRIRGTPIYFIGVSTEPVYVDEFWQSPLEFLIHDLNHAWKMMDMDSRFLQKQPKLSRDELMNKSNTFIREYFPSIAIRKTDTEQQKEMKKLKKILLFEVSHEDARPLLPNIVNEALLEDEGYEFPDDVVRYEEDVNQAYLEKRTIPGITALSYVRHKLQHGFFDQTDSQNIQIVSPKYRTVEWIVRATEELLTEMQATIPPAVQAEGLTEYLTRQACSRGPTILHSPENLDPVVGEYGDGTIIQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GX68</accession>
    <name>A0A2S9GX68_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Co-chaperonin GroES</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">10 kDa chaperonin</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Chaperonin-10</fullName>
            <shortName evidence="3">Cpn10</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">groES</name>
        <name evidence="3" type="synonym">groS</name>
        <name evidence="5" type="ORF">S2091_2976</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 4">Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3 4">Belongs to the GroES chaperonin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92317">
        <property type="protein sequence ID" value="PRC92317"/>
        <property type="gene ID" value="S2091_2976"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00320">
        <property type="entry name" value="cpn10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.33.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00580">
        <property type="entry name" value="CH10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020818">
        <property type="entry name" value="Chaperonin_GroES"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037124">
        <property type="entry name" value="Chaperonin_GroES_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018369">
        <property type="entry name" value="Chaprnonin_Cpn10_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10772">
        <property type="entry name" value="PTHR10772"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00166">
        <property type="entry name" value="Cpn10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00297">
        <property type="entry name" value="CHAPERONIN10"/>
    </dbReference>
    <dbReference type="SMART" id="SM00883">
        <property type="entry name" value="Cpn10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00681">
        <property type="entry name" value="CHAPERONINS_CPN10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00580"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC92317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="96" mass="10628" checksum="B27100B7E98A8B2B" modified="2018-07-18" version="1">MNLRPLHDRVIVKRLDQETKTASGILLPEAAAEKPDQGEILAVGNGKILDDGKVRPLEVKVGDRVLFGKYSGQAFKDNGVELLMMREEDIMAIVQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXJ7</accession>
    <name>A0A2S9GXJ7_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Dipeptidyl-peptidase</fullName>
            <ecNumber evidence="2">3.4.14.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2806</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the removal of dipeptides from the N-terminus of oligopeptides.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the peptidase S46 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.14.-" evidence="2"/>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92431">
        <property type="protein sequence ID" value="PRC92431"/>
        <property type="gene ID" value="S2091_2806"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008239">
        <property type="term" value="F:dipeptidyl-peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070009">
        <property type="term" value="F:serine-type aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043171">
        <property type="term" value="P:peptide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019500">
        <property type="entry name" value="Pep_S46"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38469">
        <property type="entry name" value="PTHR38469"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10459">
        <property type="entry name" value="Peptidase_S46"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="SSF50494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0720">Serine protease</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023049985" description="Dipeptidyl-peptidase" evidence="2">
        <location>
            <begin position="24"/>
            <end position="731"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU366067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="731" mass="80742" checksum="670E184524EA898F" modified="2018-07-18" version="1">MKKSLLLLGALSTLSTFGSIAFADEGMWMPQQLPQIAKQLKADGLQLDPNTLTKLTEFPMGAIVSLGGCSASFVSPQGLVITNHHCAYSSVSHNSSPEHNYLANGFLAKTLSDELPASPGFRVFVTTDVNNVSSKVISSSVAKLNGKKRVDAIEKNQKDLVAACEKEAGTRCNVASYYGGLEFYLIKQLEIRDVRLVHAPAEGVGKFGGDTDNWMWPRHTGDYSFFRAYVNKDGKPADFSKDNVPYVPKHYLRLASQALKEGDFVMVTGYPGRTNRHRLPSEIEQTFNWSYPAFVKASGEQLAIIAQATSGNEDLKLKYASAVASVNNYYKNRQGMLDSYAGSDILPRKEKQLADLKTWVNADPKRKQEYAHDIDQVEQLMAERDAQAKKDFLISYSTPRLLTVAKGMLRFSHESEKADIDRKIGYQEHDMARFRASTEGLDRSYDANVDQALALHFLTQYIAQPKDQRNANFDAALNLHDGMTETDLKTMLTNLYASSKLGTKEARVTWLDKKPADFNSSDDGFIKAAVALYDENMKREDRDNELAGKIQQTYANYMKAKIAYMNSIGQAIYPDANSTLRVTFGKVAGREQGADGTSWTAFTSLRGILAKNTGSGEFNAPTAQLTAIKEANQEALKTGNFGKYGDAKLNSVPVNFLATLDITGGNSGSAALNAKGELVGLAFDGTLDSIISDWDYNKTKSRSIQVDLRYILWEMTNVDHADNLLKELKVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXL6</accession>
    <name>A0A2S9GXL6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative esterase of the alpha-beta hydrolase superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_2825</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92450">
        <property type="protein sequence ID" value="PRC92450"/>
        <property type="gene ID" value="S2091_2825"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07208">
        <property type="entry name" value="Pat_hypo_Ecoli_yjju_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045943">
        <property type="entry name" value="DUF6363"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002641">
        <property type="entry name" value="PNPLA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037483">
        <property type="entry name" value="YjjU-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19890">
        <property type="entry name" value="DUF6363"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01734">
        <property type="entry name" value="Patatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="SSF52151"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51635">
        <property type="entry name" value="PNPLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="1 2" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PNPLA" evidence="3">
        <location>
            <begin position="39"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXGXXG" evidence="2">
        <location>
            <begin position="43"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXSXG" evidence="2">
        <location>
            <begin position="71"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="DGA/G" evidence="2">
        <location>
            <begin position="194"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="2">
        <location>
            <position position="73"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC92450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="313" mass="35462" checksum="5955C4F83213A871" modified="2018-07-18" version="1">MNKQDEYAVSAEETDKNFRIQVTGNEYLPQNLPARKLTLICEGGGQRGIFTAGILDSFMQQKFFPFHALLGVSSGAQNLISYACEQSGYARDAIFHYSTNKKFYNPLRFARGGHLIDLDWYFDALNQDMPLNIEHGLRRLAGRSFHMCASRRETLEPDYLSFHSNDVVQSLKASCAIPLFYRRPVVLDGVDYWDGGVADSLPVQAAHSWGSDCIVVIRTQPRESIIPLNRLPRNWRLRGLQKLGSLVESYVENYNAAMNFIENPPDAVKVIDIAPIKPLKSRLLGSSLEVLRHDYQLGRLCGGYFLENYASRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXQ7</accession>
    <name>A0A2S9GXQ7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_2866</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92491">
        <property type="protein sequence ID" value="PRC92491"/>
        <property type="gene ID" value="S2091_2866"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032834">
        <property type="entry name" value="NatK_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010559">
        <property type="entry name" value="Sig_transdc_His_kin_internal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14501">
        <property type="entry name" value="HATPase_c_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06580">
        <property type="entry name" value="His_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="25"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="64"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="95"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="152"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="domain" description="His_kinase" evidence="2">
        <location>
            <begin position="199"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="domain" description="HATPase_c_5" evidence="3">
        <location>
            <begin position="302"/>
            <end position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06580"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF14501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC92491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="398" mass="44870" checksum="3CA1B6304D2C7C65" modified="2018-07-18" version="1">MKTENRNAPSLPKLNLAAWQKLSKIFALNLVAWLTFTSIGALTSFNDDLRSGLLPDYWEIFKDWGNSAIALALLSFVIYAIFSRWPQVIANGKKIILSYGVLLLFLLPLNLFYVVKFLLSEANQSMNWVESWNASWDVIQTQILVIDDYSSLLRLSSVTAVFFAVVIVKIWQRSQARDKAWEQEHAHNLSLRLELEEQRLSALRAQLEPHFMFNALNAISALVLTDNKENALNGIHGLSELLRYALTVSEKNSVKLSEELAFLNDYIALQKLRYGSRLQITIDGVDDVIGEVNCPPLLLQPLVENALRHNLDCHQHDSDIHLSFSQQQTNILIRISNPLHDTIKTTGSNPGAGLGLRNTRARLQLAYGAYASLQTSVVNGRFQVDLLLPVSLNDYLND</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXS1</accession>
    <name>A0A2S9GXS1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92525">
        <property type="protein sequence ID" value="PRC92525"/>
        <property type="gene ID" value="S2091_2900"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021295">
        <property type="entry name" value="DUF2867"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11066">
        <property type="entry name" value="DUF2867"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="171" mass="18759" checksum="098E69C6BD384A78" modified="2018-07-18" version="1">MTNKVLLIPAPTAAIRASGLSHIDFADGYSGQADRTYVDAAQAARAAFADPPHMARCLMTLRNRIVAPFGLRASIDFSDRGLGKIDVFPIISNTGAEVVVGGDDKHLDFRIWISIKPSLKGSEVTISTLVKINSLFGRIYLCTIMPFHKLLSRMMLQRAVNRRDNVSSEAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXS3</accession>
    <name>A0A2S9GXS3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2902</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92527">
        <property type="protein sequence ID" value="PRC92527"/>
        <property type="gene ID" value="S2091_2902"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="169" mass="19328" checksum="A0F2C226BF8E69BA" modified="2018-07-18" version="1">MTLLSLSRGFNAGLQIRPRWPARQVQIDSQVLSKLQTIQAKLPAEIGLILTRGYERRASSLGFTRIHFRALGVRLFCLLYPGRRTEIMDIFGSNGHDIDGTHVDVSFLINGRRMRMLPLGVFTPLFWQQHRTRKCAVSLAQIQAALREEGFQIHRNATESLQIHCDYIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXW5</accession>
    <name>A0A2S9GXW5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC-type sugar transport system permease component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_2620</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92565">
        <property type="protein sequence ID" value="PRC92565"/>
        <property type="gene ID" value="S2091_2620"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008643">
        <property type="term" value="P:carbohydrate transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="74"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="108"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="144"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="187"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="246"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="70"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC92565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="281" mass="31335" checksum="929B38AD533DE8F7" modified="2018-07-18" version="1">MNSKLKRSILCWLALSPLVIVVLFPFVVMLLTAVKPQIEVLSYPTRWFPSHFAWQNFSEMWEATQFGTALTNSLILSSLSTLFGVAISIPAAYALARFPFRGKGLYRRFLLFTQMLSPILLVIGLFRLAAAIPYGDGNLVDSHIGVIATYTALNTAFSVWMLQSYFSTIPRDMEEAAWLEGCGRAKAVFKVFLPMAIPAIVVTAIFAFINAWNEFAVVYTLIRSPENKPLTVQIVDLVAGRYSVEWQQVMAAALLATLPVAILFSWLQKYFVKGLSMGSVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXY5</accession>
    <name>A0A2S9GXY5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2640</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92585">
        <property type="protein sequence ID" value="PRC92585"/>
        <property type="gene ID" value="S2091_2640"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015411156" evidence="2">
        <location>
            <begin position="34"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="355"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="364"/>
            <end position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="647" mass="69779" checksum="8E0CE2B9F13CE48F" modified="2018-07-18" version="1">MNFYEQPSKLLMKHALTSFLFASCCVFSTVVSAATTAEPKLTPIPPIQPAAACNAGPSWSQNGSDTQRCGLSVLRYTSPGSYYGRFEAVFRKGELAGVKGLLASETRPGFGTPGWWQETGSVGDPAQLWWGRGSDGQLWALGYESYGLLGGYISQTYYTTPQMFMNFLHGTMAPFAAAKVSYGQYGAVQTLITGGLGGTNAPITPAIVSGATLELSTTPILEGTLQFNLLVEGKNRSYQIPLKRNVKDDIGGAGASSAMMVYALKAGSMHKVGDRIVDCVHAKNAPSEDCDYDMYDVARNAHESYNAYAIFYGANSEYLAVRFDIRMDIPERNRTWANAKGLIILRANTAPGNDGQAAPIAPATPAAPATPAAPATPAAPATPAAPATSSAQSGAVENISPEKLSSVVAQSKGRTYVLLSSKDAKCGYCASANPTFAQFAGKHSKEGRFIMTTWEPWLQAFAQPGHVQFERDLLKIDGSITGLPKYLAFADGQFIGSIDGNAALKDLEQKLIQAPLPPKAVQSDAIEHIAPEQLSNVVSQSKGRLYVMLSSQDPNCIFCLRINPLFAEFANKHSKDGRFALVAWYPWLKAFDQPGRAKLEHEFHLPDGSFNGLPTFLVFDDGKYVSRINSIASFSDLEKRMFSDLQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXY7</accession>
    <name>A0A2S9GXY7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Putative metalloendopeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">S2091_2634</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92579">
        <property type="protein sequence ID" value="PRC92579"/>
        <property type="gene ID" value="S2091_2634"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08662">
        <property type="entry name" value="M13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1380.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000718">
        <property type="entry name" value="Peptidase_M13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018497">
        <property type="entry name" value="Peptidase_M13_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042089">
        <property type="entry name" value="Peptidase_M13_dom_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008753">
        <property type="entry name" value="Peptidase_M13_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11733">
        <property type="entry name" value="PTHR11733"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01431">
        <property type="entry name" value="Peptidase_M13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05649">
        <property type="entry name" value="Peptidase_M13_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00786">
        <property type="entry name" value="NEPRILYSIN"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51885">
        <property type="entry name" value="NEPRILYSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015429555" evidence="8">
        <location>
            <begin position="21"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M13_N" evidence="10">
        <location>
            <begin position="39"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M13" evidence="9">
        <location>
            <begin position="467"/>
            <end position="666"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF05649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC92579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="670" mass="75004" checksum="CF46C994DE3CA159" modified="2018-07-18" version="1">MTKFNIAGFALFFQLATCMADTPHSALEILGFDPAVRAQDDLFVAANGGWLKATEIPADKSAAYGFDLPDITAGRVRSIVEDLASKPQQAASAEQKVGEFYASYLNTAAIDQAGLTPVQAMLTEIDAIKNRKELAYWQGRMQGRIETPLWLRVFPDFKNPGINEVMTWQGGLGLPDRDYYLNQKDPRLVKAHAAYQTYLAKLASLAGIPHADAVAQRVIRLEQRIAQSHWAQADTNDPSKISHPMTLQKLITSAPGFDWQAFFQGANLADVKQINVTQLNTATTIAALFAEIPLDDWKLYFKLRSLDEAAPVLPTAFRAAHFVYRGTALQGITIEPARWQQSIDALNTALGEEVGQLYVARYFPEEQKNRMLTMVNNLLAAYRESIKNLSWMTPATKVLALDKLAKIKSKIGYPDHWRDYSNLQIDASDAVGNRHRSARFEWEYQAAKVDHKVDHDEWMMTAQTVDAYYDPMGNEIIFPAGHLQAPYFDMNADDAVNYGAIGSMIGHEISHGFDSQGSQFDGDGVMRDWWSAADHQAFEELTAKLVAQYDAEEALPGKHVDGKLTLNENIADLSGLQVAYLAYQNSLGGKPAALIDGYTGEQRFFLSYAQSWRSKVREQMQLQWLTTDPHAPHKFRANDPARNTDSFHAAFATKPGDRMYKPENERIHIW</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYB0</accession>
    <name>A0A2S9GYB0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">YD repeat (Two copies)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2758</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92703">
        <property type="protein sequence ID" value="PRC92703"/>
        <property type="gene ID" value="S2091_2758"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045351">
        <property type="entry name" value="DUF6531"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031325">
        <property type="entry name" value="RHS_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006530">
        <property type="entry name" value="YD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20148">
        <property type="entry name" value="DUF6531"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05593">
        <property type="entry name" value="RHS_repeat"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01643">
        <property type="entry name" value="YD_repeat_2x"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015566904" evidence="1">
        <location>
            <begin position="22"/>
            <end position="852"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6531" evidence="2">
        <location>
            <begin position="160"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="852" mass="90732" checksum="042472524FD6BB15" modified="2018-07-18" version="1">MKFCKWIVVIFFLLTMSAAYSQSSLTPTYSPTVKSWGPFGVTTLAGFTNLCDNFWGVNQPVQIYGPLFTYATVTYYCSVGGNEEPLDFYIQSFCPSGSLSADSTTCTCPPPTDPTTEKSFYDPVGQKCFSANQVPATPWYKPINLGCPSCSSGAPPISTGDPVHIGTGNVFEKLTDIAVSAPSSDLRLQRTYNSSPAQNAIRSFGTSWTQSYDVSIIPLGPVSPANVVLFAFPEICWQRTDNGYIWCEYPVLDSNGPKPQMVSVVRANGKGLYFISGIASGGTMHWTPDVGVTGQLTSTMASDGVTPTNYIFTDTDNHSETYDANGLLLNTLAQNGSTQQMTYSTGTTNDSSVGRYPATAPICPHVQAGAAVASGTLLCVTDNWGRQLQFEHGQPGVNESVGRITLAIDPNNQVTQYGYDGPSAGCMTVNGQQTYACLASNLTSITYPDGKTKTLYYNEAAQINGGTVCPGSAPVGNGFGYLLNTLTGIVDENGNRSVSWSYDCNGIATASQLGGGVDKYQFNIGPPDANGNSSSTVISPLGTQMTYGFTSVNGLMLGSSFAQSAGSGSGAATAISTFDTNGNPASYTDFKGNVTNYTYDMTRNLELTRVDAAGTAQARTITTSWNPTYRLPAQVAEPLHLTTYTYDTNGNLLSKTQQATSDANGSQGLSATVTGTPRSWKYTYNSVGQVLTITGPRTDVTDLTQFGYDTYGNLSSVTNAAGQITTLSNYDLNGHVGSITDPNGLTTTYVYSPRGWLTSQSKGSEVTSYNYDGVGQLISVTFPNQAKLTYTYDAAHRLTSIADNLGNTVNYTLDAMGNRTLEQVNEANGNLTRQISRVVDALNRLQQITGAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYH3</accession>
    <name>A0A2S9GYH3_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Response regulatory domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2499</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92769">
        <property type="protein sequence ID" value="PRC92769"/>
        <property type="gene ID" value="S2091_2499"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="4"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="42" mass="4596" checksum="B1042674724D59FE" modified="2018-07-18" version="1">MPMQILIVEDEPAIADTLLYALTTDGFVVEWVITGFNAAAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYM8</accession>
    <name>A0A2S9GYM8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Lipopolysaccharide biosynthesis protein LPS:glycosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2543</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92813">
        <property type="protein sequence ID" value="PRC92813"/>
        <property type="gene ID" value="S2091_2543"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008918">
        <property type="term" value="F:lipopolysaccharide 3-alpha-galactosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002495">
        <property type="entry name" value="Glyco_trans_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013645">
        <property type="entry name" value="Glyco_transf_8N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01501">
        <property type="entry name" value="Glyco_transf_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08437">
        <property type="entry name" value="Glyco_transf_8C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_transf_8C" evidence="2">
        <location>
            <begin position="268"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="325" mass="37288" checksum="0A9AF1C21D060197" modified="2018-07-18" version="1">MNPMPPTNTVTQAEQSSFHIAFCVDNHYFRAMGATILSIIVNNPGVHFTFHVLAFAVADAHRARLLKLEAEYPVKTHIHIVSPDLFSQFSHFIASTYYSPAIFTRLAIPDVLQEYTDKVLYLDADILCVGKLDELMALPMDEQIAYVVPDAEATTVRRAAALKLSQVKYFNSGVLYMNIKQWRAHRITEATIEAMLKGGNDFRFPDQDALNIALDGKATYIAKRWNYLYGLIGDLENDRRAMYDVGDAVFIHFAGAVKPWADWCLHDSRAIFAKYHGMSPWADMPMDQQPQNYKEMRMHSRFLLKRKQLGASIKWFWKYLLARPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYV8</accession>
    <name>A0A2S9GYV8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">3-oxoacyl-acyl-carrier-protein (ACP)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_2332</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92915">
        <property type="protein sequence ID" value="PRC92915"/>
        <property type="gene ID" value="S2091_2332"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013751">
        <property type="entry name" value="ACP_syn_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013747">
        <property type="entry name" value="ACP_syn_III_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08545">
        <property type="entry name" value="ACP_syn_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08541">
        <property type="entry name" value="ACP_syn_III_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ACP_syn_III" evidence="3">
        <location>
            <begin position="150"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="domain" description="ACP_syn_III_C" evidence="2">
        <location>
            <begin position="283"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC92915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="373" mass="40222" checksum="45F47C9C6D39383E" modified="2018-07-18" version="1">MNNVVISGTGLYTPPFSISNEELIVCFNSYVQQFNTEHAAAIVAGEVVALEESSVGFIEKASGIKSRYVVEKTGVLDPNRMVPHIPERSDDEPSIMCDMAVAAAQQALARAGRTASDVDAVIVACSNMQRAYPAIAVEVQTALGIDGYGYDMNVACSSATFGIQAAVSAIQSGQARAVLVINPEITSGHLNWRDRDSHFIFGDACTAILLERADSATSKHRFEIVGLKLKTQFSNNIRNNFGFLNRADESGIGKPDKLFKQQGRKVFKEVCPMAAATITDTVQKADLTIEQINRFWLHQANLNMNLLITRMMLGRDAAPEESPTILDTYANTSSAGSIIAFHTHQDDLPAGAHGVICSFGAGYSIGCVVVKKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYZ1</accession>
    <name>A0A2S9GYZ1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acetyltransferase (GNAT) domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2340</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92923">
        <property type="protein sequence ID" value="PRC92923"/>
        <property type="gene ID" value="S2091_2340"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13673">
        <property type="entry name" value="Acetyltransf_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="154" mass="17314" checksum="A6B4ACB29D9A49C0" modified="2018-07-18" version="1">MLIRKANRADSSIVWEIRNLAITAQCSKHYPFDLIMKWTSGEPPEYFSDVVDDGFWVAEIDHEIVGTGKVNLQTGKVDAVFVHPQRVRFGIGAKIIKHLEHIAIDVGLIELNLESTLNAAPFYRSCGFQGIEIAKYNSPRGIELDCILMSKKLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZ26</accession>
    <name>A0A2S9GZ26_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">Protein phosphatase CheZ</fullName>
            <ecNumber evidence="7">3.1.3.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6 7">Chemotaxis protein CheZ</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">S2091_2392</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P).</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the CheZ family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.-" evidence="7"/>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92975">
        <property type="protein sequence ID" value="PRC92975"/>
        <property type="gene ID" value="S2091_2392"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009288">
        <property type="term" value="C:bacterial-type flagellum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004721">
        <property type="term" value="F:phosphoprotein phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097588">
        <property type="term" value="P:archaeal or bacterial-type flagellum-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050920">
        <property type="term" value="P:regulation of chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007439">
        <property type="entry name" value="Chemotax_Pase_CheZ"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04344">
        <property type="entry name" value="CheZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002884">
        <property type="entry name" value="CheZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0145">Chemotaxis</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 7" id="KW-0283">Flagellar rotation</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="site" description="Enhances dephosphorylation of CheY-P" evidence="8">
        <location>
            <position position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029599"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR002884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR002884-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC92975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="224" mass="24363" checksum="D1E9589EBA862089" modified="2018-07-18" version="1">MSGLSNQGADQDAPPNEGAGEGVKQDDVLLRIGHMTRTLHDSLRGLGLDKLLKNAAEDIPNARDRLDYVAKKSEEAAQKVLNATDAAIPLQEKIDTGAKGLSGEWKALMEAEFTEAAYRALAQQTLLYLSSTNQDTSSTKSHLMDIMMAQDFQDLTGQVIKKITELAQNMEQQLIQILIDYSPADVKRSSGEGLLNGPQMNPHNKVDVVAGQEQVDDLLDSLGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZ61</accession>
    <name>A0A2S9GZ61_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphohistidine phosphatase SixA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2108</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93022">
        <property type="protein sequence ID" value="PRC93022"/>
        <property type="gene ID" value="S2091_2108"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="SSF53254"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0312">Gluconeogenesis</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="157" mass="17536" checksum="3F5534B0A8002927" modified="2018-07-18" version="1">MDLILWRHAHAEALTEDMLHRVDSERKLTPKGQKQAAKMALWLDSVLPHSCKILVSPSQRTMQTALALGRKFKVVSEIGTDSDADQILAACNWPNSREPVLIIGHQPHLGDVVSKLIPTIQDCAIRKGNVWWISQKDAEDAPTTFLKVVMTPELVVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZ93</accession>
    <name>A0A2S9GZ93_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">Polyphosphate kinase</fullName>
            <ecNumber evidence="6 7">2.7.4.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">ATP-polyphosphate phosphotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Polyphosphoric acid kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ppk</name>
        <name evidence="13" type="ORF">S2091_2109</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 7">Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>[phosphate](n) + ATP = [phosphate](n+1) + ADP</text>
            <dbReference type="Rhea" id="RHEA:19573"/>
            <dbReference type="Rhea" id="RHEA-COMP:9859"/>
            <dbReference type="Rhea" id="RHEA-COMP:14280"/>
            <dbReference type="ChEBI" id="CHEBI:16838"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="PTM">
        <text evidence="6 7">An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6 7">Belongs to the polyphosphate kinase 1 (PPK1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.1" evidence="6 7"/>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93023">
        <property type="protein sequence ID" value="PRC93023"/>
        <property type="gene ID" value="S2091_2109"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009358">
        <property type="term" value="C:polyphosphate kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008976">
        <property type="term" value="F:polyphosphate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006799">
        <property type="term" value="P:polyphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1840.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00347">
        <property type="entry name" value="Polyphosphate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003414">
        <property type="entry name" value="PP_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041108">
        <property type="entry name" value="PP_kinase_C_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024953">
        <property type="entry name" value="PP_kinase_middle"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036830">
        <property type="entry name" value="PP_kinase_middle_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025200">
        <property type="entry name" value="PPK_C_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025198">
        <property type="entry name" value="PPK_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036832">
        <property type="entry name" value="PPK_N_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30218">
        <property type="entry name" value="PTHR30218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02503">
        <property type="entry name" value="PP_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13090">
        <property type="entry name" value="PP_kinase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17941">
        <property type="entry name" value="PP_kinase_C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13089">
        <property type="entry name" value="PP_kinase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015589">
        <property type="entry name" value="PP_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140356">
        <property type="entry name" value="SSF140356"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03705">
        <property type="entry name" value="poly_P_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 6 13" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1 6 7" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PP_kinase_N" evidence="10">
        <location>
            <begin position="60"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="domain" description="PP_kinase" evidence="9">
        <location>
            <begin position="171"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="domain" description="PP_kinase_C_1" evidence="12">
        <location>
            <begin position="380"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="domain" description="PP_kinase_C" evidence="11">
        <location>
            <begin position="553"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="active site" description="Phosphohistidine intermediate" evidence="6">
        <location>
            <position position="484"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="98"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="424"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="454"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="518"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="614"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="642"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02503"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF13089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF13090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF17941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PRC93023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="736" mass="82834" checksum="E5ECB867D7A3A4D3" modified="2018-07-18" version="1">MSTSHLVNAKSTPKVKSKRKSTTIPKTTGLKKLAKTIKTNESLISSTASAPSPEKKAGQFLDREISQISFNWRVLAQAEDNNVPLLERLRYLCIASSNLDEFFEVRVASLLAHQGESTKLHPQLKATLERISIEAHRLVTRQYEVLNEDVLPQLSSQGVHLLRHNDRNPAQRAWVKAYFEREVRPLLTPIGLDPAHPFPQVVNKSLNFIVSLAGKDAFGRGTAIAIVKAPRVLPRVIRLPDELSPKGGASFCLLSSVIHAHIDDLFNGREVVAYSQFRVTRDSDMWVDEDEVKNLRVALQGELQGRQFGAAVRLEVAKNCPPNLSKFLLEQFNLHHSRLYEVNGPVNLARLSEIGELVNLPELRFTPFYANTSTPYTQPDVFAALRKQDILLHHPFQSFQTVIDFVRDASADPAVVAIKQTIYRTGMNSDLMEALISAAQAGKEVTVILELMARFDEEANINWSDRLQRAGAQVVYGVVGLKTHAKLALVIRREVGHQLRCYAHLGTGNYHPTTTKFYTDFGLLTANPTIASEVNEVFIHLTSLTKHKKFQHLWLAPFSFQNQLIRAIRNEARLARAGKPGRIIAKMNALLDESVIRALYAASNDGVKIELIVRGACALRPGVPGLSENISVRSIIGRFLEHSRIFYFRNDLAHDTYLSSADWMNRNLFRRIEVAFPILDKNLKKRVMEEGLMPYLKDNCNAWLLDEDGEYKLRKSRAKPYGAQQYLMDTLGQTDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZE8</accession>
    <name>A0A2S9GZE8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Peptidase S24-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">S2091_2198</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the peptidase S24 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93112">
        <property type="protein sequence ID" value="PRC93112"/>
        <property type="gene ID" value="S2091_2198"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009432">
        <property type="term" value="P:SOS response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06529">
        <property type="entry name" value="S24_LexA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039418">
        <property type="entry name" value="LexA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036286">
        <property type="entry name" value="LexA/Signal_pep-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006197">
        <property type="entry name" value="Peptidase_S24_LexA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015927">
        <property type="entry name" value="Peptidase_S24_S26A/B/C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00717">
        <property type="entry name" value="Peptidase_S24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00726">
        <property type="entry name" value="LEXASERPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51306">
        <property type="entry name" value="SSF51306"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0068">Autocatalytic cleavage</keyword>
    <keyword evidence="2" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5" id="KW-0234">DNA repair</keyword>
    <keyword evidence="3 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0742">SOS response</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015485987" evidence="8">
        <location>
            <begin position="24"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S24" evidence="9">
        <location>
            <begin position="20"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC93112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="141" mass="15557" checksum="568AD962FF2D5B2D" modified="2018-07-18" version="1">MNSPIPTLSTPARIVLFSSPVCAGFPSPATDYAQHSINLNEYLISNANASFLFTVRGESMSGIGIYDGDTLIVDRSITPAHNNIVIAVVDEDYTVKRLYQRNNIVKLLAENPAFPPIELKDGQELRIWGVATFNLHNLLRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZJ2</accession>
    <name>A0A2S9GZJ2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Peptidase family M48</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_2122</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="6">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the peptidase M48 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93036">
        <property type="protein sequence ID" value="PRC93036"/>
        <property type="gene ID" value="S2091_2122"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001915">
        <property type="entry name" value="Peptidase_M48"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01435">
        <property type="entry name" value="Peptidase_M48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 6" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1 6" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="4 6" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015480594" evidence="7">
        <location>
            <begin position="24"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M48" evidence="8">
        <location>
            <begin position="58"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC93036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="250" mass="28328" checksum="4EC749ACEC2FE99E" modified="2018-07-18" version="1">MTNKYPHLALIVAFFMLCMSAQAVTREEVVAGAELLYRARIVEAQSKFQLDNDPAFLARVQRIALGLIEQAKREHPVTAALDWEIHTSDDPEESAFCMAGGKMLVSHNYVNTMDLNNAELAMLLSHEIQHAVLEHNLKEFQEALRIEPNLQKYSFLALEDAVDHDETLMAKLSKFNVEQENQADLEGLQMAWRAGWPALKLAGFFQKLARIDPMAHFDSLEHPAPARRWQAARKLAEELDQIKAPAVPMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZJ7</accession>
    <name>A0A2S9GZJ7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putative small secreted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_2237</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the EcnA/EcnB lipoprotein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93151">
        <property type="protein sequence ID" value="PRC93151"/>
        <property type="gene ID" value="S2091_2237"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009636">
        <property type="term" value="P:response to toxic substance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012556">
        <property type="entry name" value="Entericidin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08085">
        <property type="entry name" value="Entericidin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015680600" evidence="5">
        <location>
            <begin position="20"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC93151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="47" mass="4919" checksum="A94A857A380EE40A" modified="2018-07-18" version="1">MKKFALCCLAVLAITVLSACNTIEGFGKDVKNAGQSMENAAAKKTNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZN2</accession>
    <name>A0A2S9GZN2_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta</fullName>
            <shortName evidence="13">ACCase subunit beta</shortName>
            <shortName evidence="13">Acetyl-CoA carboxylase carboxyltransferase subunit beta</shortName>
            <ecNumber evidence="13">2.1.3.15</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">accD</name>
        <name evidence="15" type="ORF">S2091_2246</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12 13">Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>acetyl-CoA + N(6)-carboxybiotinyl-L-lysyl-[protein] = malonyl-CoA + N(6)-biotinyl-L-lysyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:54728"/>
            <dbReference type="Rhea" id="RHEA-COMP:10505"/>
            <dbReference type="Rhea" id="RHEA-COMP:10506"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:57384"/>
            <dbReference type="ChEBI" id="CHEBI:83144"/>
            <dbReference type="ChEBI" id="CHEBI:83145"/>
            <dbReference type="EC" id="2.1.3.15"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="13">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="13">Lipid metabolism; malonyl-CoA biosynthesis; malonyl-CoA from acetyl-CoA: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="13">Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 13">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the AccD/PCCB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.3.15" evidence="13"/>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93160">
        <property type="protein sequence ID" value="PRC93160"/>
        <property type="gene ID" value="S2091_2246"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00655">
        <property type="reaction ID" value="UER00711"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009317">
        <property type="term" value="C:acetyl-CoA carboxylase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003989">
        <property type="term" value="F:acetyl-CoA carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016743">
        <property type="term" value="F:carboxyl- or carbamoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:2001295">
        <property type="term" value="P:malonyl-CoA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01395">
        <property type="entry name" value="AcetylCoA_CT_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034733">
        <property type="entry name" value="AcCoA_carboxyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000438">
        <property type="entry name" value="Acetyl_CoA_COase_Trfase_b_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011762">
        <property type="entry name" value="COA_CT_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041010">
        <property type="entry name" value="Znf-ACC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01039">
        <property type="entry name" value="Carboxyl_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17848">
        <property type="entry name" value="zf-ACC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01070">
        <property type="entry name" value="ACCCTRFRASEB"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00515">
        <property type="entry name" value="accD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50980">
        <property type="entry name" value="COA_CT_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="13" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11 13" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="7 13" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="2 13" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="10 13" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="4 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 13 15" id="KW-0808">Transferase</keyword>
    <keyword evidence="8 13" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 13" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CoA carboxyltransferase N-terminal" evidence="14">
        <location>
            <begin position="27"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C4-type" evidence="13">
        <location>
            <begin position="31"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="31"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="34"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="50"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="53"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00025280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="PRC93160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="290" mass="31697" checksum="8936EAB3DBD2F872" modified="2018-07-18" version="1">MSWLEKLLPPRIQRNDAGTRKSIPEGLWVKCPSCEAVLYRSDLEVNLHVCPKCSHHMRISARERLDSLLDVGGHYEIGQETLPVDTLKFKDSKKYPDRLKAAMESTGETDALVVIGGSIMSMPVVVACFEFGFMAGSMGSVVGERFVRGAQAALEQKVPFICITATGGARMQEGLLSLMQMAKTTAMLTKLSEKKLPFISVLTDPTTGGVSASFAFMGDVVMAEPKALIGFAGARVIENTVREKLPEGFQRSEFLLTKGAIDMIVDRRKMREEIAKLLALLQSQPAEAVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZS3</accession>
    <name>A0A2S9GZS3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1970</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93232">
        <property type="protein sequence ID" value="PRC93232"/>
        <property type="gene ID" value="S2091_1970"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="150" mass="16813" checksum="DF2F1FA95BDE564A" modified="2018-07-18" version="1">MLELITPNLLKELVAANVVCSAEVVGEKGGYVVLVKYGVGERVVAARDNTGHIKRRIFASLDSVDNFLRKIVHIVDYRVASANFEAAPRQARYEKNSARLKEVHESAAYDKWFRSQVQEALDDPRPAIPHEDIKKEFAALRAELALKAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZV7</accession>
    <name>A0A2S9GZV7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1999</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93261">
        <property type="protein sequence ID" value="PRC93261"/>
        <property type="gene ID" value="S2091_1999"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038729">
        <property type="entry name" value="Rad50/SbcC_AAA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13304">
        <property type="entry name" value="AAA_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13476">
        <property type="entry name" value="AAA_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="1">
        <location>
            <begin position="43"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="243" mass="26997" checksum="083BFC5319DB3DB4" modified="2018-07-18" version="1">MSNTLSARPYLQEISIRPDADIDLNSYPFSIPAVQELNFLKFHPDVTFFVGENGSGKSTILEAIALAMGFGPEGGSKNVQLLYTTDSVSPLHASLKLRKSFRKPTDGYFLRAESFFNVATYMDAIGTPDRSLHACSHGEAFMQLLINKFRGNGLYLLDEPEAALSPNRQLAALSAIHQLVQNESQFIIATHSPILLAYPNAKILQFDGTGIAEVAYEDTEHFAITRDFLNHYPRRLEQLLGDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZY2</accession>
    <name>A0A2S9GZY2_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF1737 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1998</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93260">
        <property type="protein sequence ID" value="PRC93260"/>
        <property type="gene ID" value="S2091_1998"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013619">
        <property type="entry name" value="DUF1737"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08410">
        <property type="entry name" value="DUF1737"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF1737" evidence="1">
        <location>
            <begin position="14"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08410"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="71" mass="7671" checksum="38D85BBA0168328F" modified="2018-07-18" version="1">MNANASSPPDNLPTYRVLTGPDDAKFCMRVSEAVALGYKLYGPPSVTYNNEKVIVAQAVIWPSIEASISKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0D9</accession>
    <name>A0A2S9H0D9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2064</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93326">
        <property type="protein sequence ID" value="PRC93326"/>
        <property type="gene ID" value="S2091_2064"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="62"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="90"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="171" mass="18724" checksum="1FC8D13C7EF10900" modified="2018-07-18" version="1">MRRRCYFMLPDIASARAMLDQLLLARVEERYIHFLASPDTLPADMPEATLFQRTDLVHGTEVGIFIGAFSGLMASGLMLILPLVRLETQIVSFILCGIMGAVLGAWLAARASTAIPNSALEQYSNGILQGQVLLMVDLPVGRMGEIKEMINKSYPMKANLEPEISTNPSIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0E3</accession>
    <name>A0A2S9H0E3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1815</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93428">
        <property type="protein sequence ID" value="PRC93428"/>
        <property type="gene ID" value="S2091_1815"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036237">
        <property type="entry name" value="Xyl_isomerase-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51658">
        <property type="entry name" value="SSF51658"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="404" mass="44632" checksum="11D36E247832CEF5" modified="2018-07-18" version="1">MQLNHLPAAPHLMYCTNIHAAENWGEISASLDEHLPLIKQELKSSSTLIEPFALGLRLSAIAANELSQPEHLEELKSQLSRLNAYVPSINAFPYGGFHTAPIKQLVYQPDWLTTKRQTYTLQCAQILAQLLPDGVSGSISTVPGAFKSQPWHVENNLHIAHHLIEVAAGLVKLERGSGKLIALALEPEPCCMLETVAETIHFFQNFLFSPEAVSTFAKLIGVNRSDAEALLRRHIGVCYDVCHAAVEFENPVDALQSLQAAGIGIPKIQLSCALRIPQMLAELHPAVMRFNDGVYLHQVVVSQQGKLQRFTDLPEALSAFEQGTADGEWRIHCHVPVFLSQLDLFESTQAELLAVLQALRSNTFSAHLEIETYTWDVLPAAFKTESKATAIAREIAFIMKEIAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0J1</accession>
    <name>A0A2S9H0J1_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Antitoxin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1874</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Antitoxin component of a type II toxin-antitoxin (TA) system.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the phD/YefM antitoxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93487">
        <property type="protein sequence ID" value="PRC93487"/>
        <property type="gene ID" value="S2091_1874"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006442">
        <property type="entry name" value="Antitoxin_Phd/YefM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036165">
        <property type="entry name" value="YefM-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02604">
        <property type="entry name" value="PhdYeFM_antitox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143120">
        <property type="entry name" value="SSF143120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009981"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU362080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="80" mass="8833" checksum="2E9A76E569D8528C" modified="2018-07-18" version="1">MDTITASEARASLYRLIDQAAESHEPVTIKGKRSSAVLISAEDWSAIQETLFLLAVPGMRESIKDAMAEPLSKSNRTLKW</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0X8</accession>
    <name>A0A2S9H0X8_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 6">ATP-dependent DNA helicase RecG</fullName>
            <ecNumber evidence="3 6">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">recG</name>
        <name evidence="9" type="ORF">S2091_1646</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>ATP + H2O = ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the helicase family. RecG subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="3 6"/>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93645">
        <property type="protein sequence ID" value="PRC93645"/>
        <property type="gene ID" value="S2091_1646"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004609">
        <property type="entry name" value="ATP-dep_DNA_helicase_RecG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045562">
        <property type="entry name" value="RecG_dom3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033454">
        <property type="entry name" value="RecG_wedge"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19833">
        <property type="entry name" value="RecG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17191">
        <property type="entry name" value="RecG_wedge"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00643">
        <property type="entry name" value="recG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5 6" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="6" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6 9" id="KW-0347">Helicase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="7">
        <location>
            <begin position="282"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="8">
        <location>
            <begin position="484"/>
            <end position="630"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00017846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC93645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="699" mass="77296" checksum="4BBFAF447AB3AB7B" modified="2018-07-18" version="1">MPAANKVTVIEKAKPTAASKLAANLAKLGLRTDMDLALHLPMRYVDETQITPIQQAALQGGHMVQVEGLVTACDVQYKPRRQLVVTLADDSSQLVLRFLNFYGSQITQLAVGTRVRARAELRHGFFGSEMVHPEYKVVNENAPLPTQLTPVYPSGVGVSQASLRREIRAAMLRINWQDTLPADLRAQFDLIEFAEAVKVLHNPPANVDEYSLEDRSHPAWQRMKFDELLAQQLSLQRAQFSRRSKSAPSLACVGEVSNAFLMGLPFALTSAQQRVLSEIRTDISAAHPMQRLLQGDVGSGKTIVAALAAAQAIDSGYQAVLMAPTEILADQHFRKIAAWLEPLGISVVWLTGSLKKKEKQTAREQIEAGTAQLVIGTHALLQDEVKFARLGLVIVDEQHRFGVDQRLTLRNKGNGTDTINKLIPHQLMMSATPIPRTLAMTYYADLEISVIDELPPGRTPIMTRVIDQERRSEVIARVSVAAADGRQIYWVCPLIEESEALQLQTATDTYLMLQEALPDLQIGLVHGRMKPTEKQAVMANFIAGITHLLVATTVIEVGVDVPNASLMVIEHAERFGLSQLHQLRGRVGRGTAASVCLLLYQAPLGGIAKQRLMMMRSSTDGFEIARKDLEIRGPGEFLGARQAGQAMLRFADLENDQWLVEQARGLAQTLLQNLLPNSPEIVAAHLLRWMNHKEEYLRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H111</accession>
    <name>A0A2S9H111_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphatidylglycerophosphate synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1675</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93674">
        <property type="protein sequence ID" value="PRC93674"/>
        <property type="gene ID" value="S2091_1675"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016780">
        <property type="term" value="F:phosphotransferase activity, for other substituted phosphate groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000462">
        <property type="entry name" value="CDP-OH_P_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043130">
        <property type="entry name" value="CDP-OH_PTrfase_TM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01066">
        <property type="entry name" value="CDP-OH_P_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="118"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="160"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="202" mass="22371" checksum="AEF86370AECEB719" modified="2018-07-18" version="1">MKFSIYQIKPQFQRLLSPVLNTLIFCRVTPNQITVLAMSLSLLFGVALTVFPQHRWLWFAYPAFMLLRMMLNAIDGMLANATGQKTSLGAMLNEMGDQVSDVALYLPFAFLANVSAQLSVMVVILALLAEFAGVIAILTGSTRRFDGPMGKSDRAFSFGVLALLVAFNAASFWLNGVLSLMMLLLVWTIFNRLHHQIVPPTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H193</accession>
    <name>A0A2S9H193_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Nucleoside-diphosphate-sugar pyrophosphorylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1363</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93754">
        <property type="protein sequence ID" value="PRC93754"/>
        <property type="gene ID" value="S2091_1363"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005835">
        <property type="entry name" value="NTP_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00483">
        <property type="entry name" value="NTP_transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NTP_transferase" evidence="2">
        <location>
            <begin position="2"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="242" mass="26390" checksum="EB8B319B9C334DEC" modified="2018-07-18" version="1">MKAILLAAGRGVRMMPLTEHCPKPLLKVRGRPLIVWHILNLVKAGISEIVINHAYLGDMIEKTLGDGSQFGAQISYSPETTALETAGGIANALHLLGDQPFVAVAADIYCPHFDFSECLNTLEDNDMWGNPHPIDKRDIAWLYMVKNPRHHPNGDFAVNLLGLSNEGEPRATFSGIGVYRPEMFASIEPGTSAKLVSLFRDYADRGQLGGEVVHCAWTDVGTPERLAELNTPLTSSSMTLPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1A8</accession>
    <name>A0A2S9H1A8_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">UPF0056 membrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_1748</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the UPF0056 (MarC) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93747">
        <property type="protein sequence ID" value="PRC93747"/>
        <property type="gene ID" value="S2091_1748"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002771">
        <property type="entry name" value="Multi_antbiot-R_MarC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33508">
        <property type="entry name" value="PTHR33508"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01914">
        <property type="entry name" value="MarC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00427">
        <property type="entry name" value="TIGR00427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="51"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="149"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="191"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC93747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="224" mass="24239" checksum="05F86C961DC66E5E" modified="2018-07-18" version="1">MQHIFYEIFATILATMTALLPIANPLTTVAVLPAIAAHLTPTERAIQVRRACFYMAAILVVFLLAGAVLMDFFSISIPGLRIAGGLIVCKFGFNMLFPPAEQTHEQNLNNKRDISFSPLAMPTLSGPGSIAVVISMSTGVHSQTALPIWLGYLSVVFGILLVAYTSWLVLRASERLTSLLGADGIEAVSRIMGFLLICIGVQFVINGIGNLLHDPLFWPELLTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1D1</accession>
    <name>A0A2S9H1D1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Xaa-Pro aminopeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_1362</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the peptidase M24B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93753">
        <property type="protein sequence ID" value="PRC93753"/>
        <property type="gene ID" value="S2091_1362"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007865">
        <property type="entry name" value="Aminopep_P_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029149">
        <property type="entry name" value="Creatin/AminoP/Spt16_NTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001131">
        <property type="entry name" value="Peptidase_M24B_aminopep-P_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05195">
        <property type="entry name" value="AMP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01011">
        <property type="entry name" value="AMP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53092">
        <property type="entry name" value="SSF53092"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="SSF55920"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00491">
        <property type="entry name" value="PROLINE_PEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0464">Manganese</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP_N" evidence="8">
        <location>
            <begin position="3"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC93753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="450" mass="49818" checksum="E10F1AC356EE7C65" modified="2018-07-18" version="1">MNSTFKSYLDRRASLLAQMQAQGGGVAILATAPEMTRNSDCFFPFRHDSYFYYLTGFTEPEAVVVLVAGKTQQSILFCREKNLEREIWDGFRYGPQAAQAHFGFDAAYPIEELEQQLANLLADAPTIFHTQGYNNQLDTQLQRSINTVRGRARSGVLAPQKSTDLHALLNEMRLIKDASEIALMQRAASISAVAHQRAMQITLPGLFEYELEAELLHEFRRQGSQSPAYGSIVATGANACVLHYSANNAKITDGDLILIDAGCEFDSYASDVTRTFPANGKFNAPQKTLYELVLAAQSAALAHAKIGARYIDGHNAAIQVLTQGMLDTGLLDKNKVGSLEDAISSNAYRQFYMHGTGHWIGMDVHDVGNYRVTTAQNGTEEKPYRQLQAGMAITIEPGIYVRPAEGVPEQFWNIGIRIEDDIIITENGPLNLSRDTPKTVAEIEEVMRRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1H1</accession>
    <name>A0A2S9H1H1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Tim44-like domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_1409</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93800">
        <property type="protein sequence ID" value="PRC93800"/>
        <property type="gene ID" value="S2091_1409"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007379">
        <property type="entry name" value="Tim44-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04280">
        <property type="entry name" value="Tim44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00978">
        <property type="entry name" value="Tim44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="77"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="107"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="Tim44" evidence="3">
        <location>
            <begin position="175"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC93800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="308" mass="32324" checksum="ABA3CE93F5D166A1" modified="2018-07-18" version="1">MKKFVTVVMMMASAFFMTINDAEAKRMGGGGSSGRQSQNVSKQQAPAQQGANQTQPATPAAAPGATPAKSASPWKGMLGGALLGLGLGALLSSFGIGGALASMISTLLMAGIGVALVMFVFRMLKKKPTSSPFQTAYAGANSYNSTPEIGSRLNSDDTPKARETINGSGFGSNVAAEASDATWDIPADFDVPGFERNAKTYFIRLQAAWDKADINDIREFTTPEMYAEVKLQIQERGAGSNVTDVLTINSKLLGIETQGADYLASVKFTGTIKEAPDAPTESFDEVWNLVKSMDGAGGWLLAGIQQVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H231</accession>
    <name>A0A2S9H231_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1535</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93926">
        <property type="protein sequence ID" value="PRC93926"/>
        <property type="gene ID" value="S2091_1535"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="147" mass="15888" checksum="4AFDE8143F24A896" modified="2018-07-18" version="1">MALYHLLINAGNADCLRNRRDVTDAIVSVSGAIAVRAGDNGAAALSDDSDILKAAWHGHQHARDEINGAHRLLQGACRLRTAVQRLRDGLPIVASLNCVIILRTLLRERGIAANRRCYVLINRPAWGLADLGYIASTVFNLTDIPGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H273</accession>
    <name>A0A2S9H273_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA 2',3'-cyclic phosphodiesterase</fullName>
            <shortName evidence="1">RNA 2',3'-CPDase</shortName>
            <ecNumber evidence="1">3.1.4.58</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1233</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 3'-end 2',3'-cyclophospho-ribonucleotide-RNA + H2O = a 3'-end 2'-phospho-ribonucleotide-RNA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:11828"/>
            <dbReference type="Rhea" id="RHEA-COMP:10464"/>
            <dbReference type="Rhea" id="RHEA-COMP:17353"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:83064"/>
            <dbReference type="ChEBI" id="CHEBI:173113"/>
            <dbReference type="EC" id="3.1.4.58"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the 2H phosphoesterase superfamily. ThpR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.4.58" evidence="1"/>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94060">
        <property type="protein sequence ID" value="PRC94060"/>
        <property type="gene ID" value="S2091_1233"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004113">
        <property type="term" value="F:2',3'-cyclic-nucleotide 3'-phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008664">
        <property type="term" value="F:2'-5'-RNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01940">
        <property type="entry name" value="RNA_CPDase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009097">
        <property type="entry name" value="Cyclic_Pdiesterase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004175">
        <property type="entry name" value="RNA_CPDase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35561">
        <property type="entry name" value="PTHR35561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55144">
        <property type="entry name" value="SSF55144"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02258">
        <property type="entry name" value="2_5_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="short sequence motif" description="HXTX 1" evidence="1">
        <location>
            <begin position="146"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="HXTX 2" evidence="1">
        <location>
            <begin position="226"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="1">
        <location>
            <position position="146"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="277" mass="31963" checksum="6C0661021EAC1CA6" modified="2018-07-18" version="1">MEIFIWKICRCCRTLKDAARALTSLLITPPHTKQIQHRQRRSPVPQTPIGFVACKPTYLAKFSQLTILILSRNWYRVLASKGDFRLLKVEHKSEFDMEKSPRNIDSTSRLFLALWPETTIQNKLKCWSDDCSWPSSASLMRPESLHLTLHFIGNVPNSRLPELVQGLKVSFHPFDLSFGRPEMWAHGVAVLKPDSVPDNLLELHASLEPVLRRLTLPIETRPFLPHITFARHAADALLPALEQEQRIHWHVDGYALIKSQQIPEGRYTLVQRYAHKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2A7</accession>
    <name>A0A2S9H2A7_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Translation initiation factor IF-1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">infA</name>
        <name evidence="7" type="ORF">S2091_1294</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the IF-1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005663428.1">
        <property type="nucleotide sequence ID" value="NZ_PUGF01000004.1"/>
    </dbReference>
    <dbReference type="SMR" id="A0A2S9H2A7"/>
    <dbReference type="EnsemblBacteria" id="PRC94121">
        <property type="protein sequence ID" value="PRC94121"/>
        <property type="gene ID" value="S2091_1294"/>
    </dbReference>
    <dbReference type="GeneID" id="56944259"/>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04451">
        <property type="entry name" value="S1_IF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00075">
        <property type="entry name" value="IF_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006196">
        <property type="entry name" value="RNA-binding_domain_S1_IF1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022967">
        <property type="entry name" value="S1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004368">
        <property type="entry name" value="TIF_IF1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33370">
        <property type="entry name" value="PTHR33370"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01176">
        <property type="entry name" value="eIF-1a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00008">
        <property type="entry name" value="infA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50832">
        <property type="entry name" value="S1_IF1_TYPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 4 5" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="4 5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 4" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="S1-like" evidence="6">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC94121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="72" mass="8239" checksum="98263C780BBB13A0" modified="2018-07-18" version="1">MAKDDVIQMQGEILENLPNATFRVKLENGHVVLGHISGKMRMNYIRILPGDKVTVELTPYDLSRARIVFRTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2Y5</accession>
    <name>A0A2S9H2Y5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0966</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94345">
        <property type="protein sequence ID" value="PRC94345"/>
        <property type="gene ID" value="S2091_0966"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="57" mass="6398" checksum="623F0734EEE748C8" modified="2018-07-18" version="1">MRNCRDVAVKIAVRNATTLCTKINSQTDTGDEVGKYLESFVSPKYRNVMTVSLDQDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H393</accession>
    <name>A0A2S9H393_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Glutaredoxin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_1076</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glutaredoxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94455">
        <property type="protein sequence ID" value="PRC94455"/>
        <property type="gene ID" value="S2091_1076"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097573">
        <property type="term" value="F:glutathione oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004362">
        <property type="term" value="F:glutathione-disulfide reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03418">
        <property type="entry name" value="GRX_GRXb_1_3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011767">
        <property type="entry name" value="GLR_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002109">
        <property type="entry name" value="Glutaredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014025">
        <property type="entry name" value="Glutaredoxin_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011900">
        <property type="entry name" value="GRX_bact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00462">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00160">
        <property type="entry name" value="GLUTAREDOXIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02181">
        <property type="entry name" value="GRX_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00195">
        <property type="entry name" value="GLUTAREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0249">Electron transport</keyword>
    <keyword evidence="2 3" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Glutaredoxin" evidence="4">
        <location>
            <begin position="5"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU364065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC94455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="87" mass="9928" checksum="9DB3CA634DFE706F" modified="2018-07-18" version="1">MTVQVKMYSTGVCPYCIMAERLLQSKGVDQIEKVRIDLDPQQRELMMQQTGRRTVPQIYIGEHHVGGFDDLTVLDRSGKLDELLHPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3H1</accession>
    <name>A0A2S9H3H1_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">D-amino acid dehydrogenase</fullName>
            <ecNumber evidence="4">1.4.99.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">dadA</name>
        <name evidence="6" type="ORF">S2091_0532</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Oxidative deamination of D-amino acids.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 4">
            <text>A + a D-alpha-amino acid + H2O = a 2-oxocarboxylate + AH2 + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:18125"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:35179"/>
            <dbReference type="ChEBI" id="CHEBI:59871"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 4">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the DadA oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.4.99.-" evidence="4"/>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94529">
        <property type="protein sequence ID" value="PRC94529"/>
        <property type="gene ID" value="S2091_0532"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008718">
        <property type="term" value="F:D-amino-acid dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019478">
        <property type="term" value="P:D-amino acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01202">
        <property type="entry name" value="DadA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023080">
        <property type="entry name" value="DadA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DAO" evidence="5">
        <location>
            <begin position="2"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="3"/>
            <end position="17"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009410"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC94529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="416" mass="44897" checksum="3721C18988579723" modified="2018-07-18" version="1">MRVVILGSGVIGVTSAYYLALAGHEVTVLDRQTGPALETSFANAGQISPGYAAPWAAPGVPLKALKWMLQEHAPLSIAPDGTMFQLRWMWQMLINCSVSHYAVNKQRMVHLAEYSRDCFKDLRAATNIQYEGRQQGTLQLFRTDEQYDSAQKDIAVLKQAGVPYELLSAAQLADAEPALAAVKDKLKGGLRLPNDETGDCQLFTTTLSNMAEKLGVQFRYGVSIDALNMAGGKIASVQCGSEIVIADAYVVALGSYSTNFLRGILDIPVYPVKGYSITVPIIDAAKAPVSTILDETYKIAITRFDNRIRVGGMAELVGFNTKLKAKRQATLEMVLNDLFPGAGDLEHDSFWTGLRPMTPDGTPLVGATKVPNLFLNTGHGTLGWTMSCGSGSVLADIISGKNPAIDASELNLTRYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3I5</accession>
    <name>A0A2S9H3I5_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Glutathione peroxidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_1047</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the glutathione peroxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94426">
        <property type="protein sequence ID" value="PRC94426"/>
        <property type="gene ID" value="S2091_1047"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004602">
        <property type="term" value="F:glutathione peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00340">
        <property type="entry name" value="GSH_Peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000889">
        <property type="entry name" value="Glutathione_peroxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029759">
        <property type="entry name" value="GPX_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029760">
        <property type="entry name" value="GPX_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11592">
        <property type="entry name" value="PTHR11592"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00255">
        <property type="entry name" value="GSHPx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000303">
        <property type="entry name" value="Glutathion_perox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01011">
        <property type="entry name" value="GLUTPROXDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00460">
        <property type="entry name" value="GLUTATHIONE_PEROXID_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00763">
        <property type="entry name" value="GLUTATHIONE_PEROXID_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51355">
        <property type="entry name" value="GLUTATHIONE_PEROXID_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2 5 7" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="6">
        <location>
            <begin position="1"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000303-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC94426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="161" mass="17810" checksum="EDFA0F24E2D90193" modified="2018-07-18" version="1">MSNVYDFSATSLAGQPVSLSDYKGKVILIVNTASACGFTPQYKGLEALYQEFKDLGVVVLGFPCNQFGRQEPGTALEIGAFCEKNYGVTFPLFEKIDVNGDEAHPLFQYLKQHAPGVLGSAAIKWNFTKFLIKKDGTVYDRYAPLTKPEELIEDVKSLLEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3I7</accession>
    <name>A0A2S9H3I7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Mg chelatase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0530</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94527">
        <property type="protein sequence ID" value="PRC94527"/>
        <property type="gene ID" value="S2091_0530"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032508">
        <property type="term" value="P:DNA duplex unwinding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045006">
        <property type="entry name" value="CHLI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001208">
        <property type="entry name" value="MCM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004482">
        <property type="entry name" value="Mg_chelat-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025158">
        <property type="entry name" value="Mg_chelat-rel_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000523">
        <property type="entry name" value="Mg_chelatse_chII-like_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32039">
        <property type="entry name" value="PTHR32039"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32039:SF7">
        <property type="entry name" value="PTHR32039:SF7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01078">
        <property type="entry name" value="Mg_chelatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13335">
        <property type="entry name" value="Mg_chelatase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01657">
        <property type="entry name" value="MCMFAMILY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00368">
        <property type="entry name" value="TIGR00368"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50051">
        <property type="entry name" value="MCM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MCM" evidence="2">
        <location>
            <begin position="298"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="509" mass="55452" checksum="6E8A92491B199249" modified="2018-07-18" version="1">MSLAVLKSRALSGMDAPEVTVEVHLANGLPSFTIVGLPEAEVKEAKDRVRAALQNSRFEFPNRRITVNLAPADLPKESGRFDLPIALGILAASEQIPADTLNHYEFAGELSLSGELRPIRGALAMTFAMCNDGAAKNVAKKIAFILPRANADEAALVEQAHIYPADSLLQVAAHFAAHSAEARLTRHTPSPQIRRPHYSDFSEVKGQLLAKRALEVAACGLHSVLLIGPPGTGKSMLASRFSGILPSMNDIEALEAAAVQSLTQGFSLAQWKVRPFRSPHHTASAVALVGGGGTPRPGEISLAHRGVLFLDELPEFDRRVLEVLREPLESGRITISRAARQADFPARFQLIAAMNPCPCGYLGHVNGKCHCSPDVVARYQGKISGPLLDRIDMQIQVGSLPHADLIKQADGEASEQIQARVERAFDLQLARQGKANNMLNTVEIEQFCDPDAEGKQLLHNAMNRLNWSARSYHRVLKVARSIADLEQIEQIQRAHIAEAISYRRALKEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3K5</accession>
    <name>A0A2S9H3K5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_0553</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94550">
        <property type="protein sequence ID" value="PRC94550"/>
        <property type="gene ID" value="S2091_0553"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="SSF49785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015611981" evidence="3">
        <location>
            <begin position="35"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="197"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="221"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="254"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="286"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="310"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="339"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="370"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="388"/>
            <end position="415"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC94550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="621" mass="70452" checksum="17355DD5CB79A7A0" modified="2018-07-18" version="1">MKPQNWAFSAPDCRGAVNLLATLFLVFCCTLAQAQEQVNAQQSVSRIKQAEFIISDSPTIPPASANWQPVLLPHHVPKPADFELIHYWYKTTFEVKAGSEPLWMLFPQLLSGGDVYVNGALIGEKPSASKRAQVRWYLPELWLIPPLSLHEGSNEIEVKLAIREPFTSFGEIDIGPEKMQRNTFNQLLFWEDTTADISTALCMLAGIFIIIFWARRPQEKLYGMFGVCVLFWGLRTLLLRTPVVSIDFFLLWRFSYYFTTAGFIVLISIFMLKFSDRNNIVYNRVLIGYWFIGCTAFLAIGMPIRHFLEAFWLTGFLPLNLYAVACILIYAARQRTHNAVSMGLAILFALGLSVHDLAVQEAWVDWPEIYLMHLGIPAFLLVMIGILLDRFLDSLAQVESVNEQLELRVAAREVELKQSYEQLGKLGRAHAATEERHRIMQDMHDGVGTQLLSTLMMAQSEELPQKTMVALLQECLDDMRLVIDSLSPDDCDLLPVLGNFRFRMEARFRAIGLNFEWRNHSIPDELELEPDAGLQVLRILQEALANTLKHSQAKNVIVELFFYPHSLCIRIIDDGVGFVEATQSKGRGMINMRARAQKIGASFKIKHTSPGTEVVLDIPLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3U5</accession>
    <name>A0A2S9H3U5_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Fused isobutyryl-CoA mutase</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="5">Isobutyryl-CoA mutase</fullName>
                <shortName evidence="5">ICM</shortName>
                <ecNumber evidence="5">5.4.99.13</ecNumber>
            </recommendedName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="5">P-loop GTPase</fullName>
                <ecNumber evidence="5">3.6.5.-</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="5">G-protein chaperone</fullName>
            </alternativeName>
        </domain>
    </protein>
    <gene>
        <name evidence="5" type="primary">icmF</name>
        <name evidence="7" type="ORF">S2091_0643</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>2-methylpropanoyl-CoA = butanoyl-CoA</text>
            <dbReference type="Rhea" id="RHEA:13141"/>
            <dbReference type="ChEBI" id="CHEBI:57338"/>
            <dbReference type="ChEBI" id="CHEBI:57371"/>
            <dbReference type="EC" id="5.4.99.13"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>GTP + H2O = GDP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>adenosylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:18408"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="domain">
        <text evidence="5">Is composed of four functional domains: the N-terminal 5'-deoxyadenosylcobalamin binding region that is homologous to the small subunit of ICM (IcmB), a middle P-loop GTPase domain (MeaI) that likely acts as a chaperone for ICM, a structured linker region involved in dimer formation, and a C-terminal part that is homologous to the large substrate-binding subunit of ICM (IcmA).</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the IcmF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.13" evidence="5"/>
    <dbReference type="EC" id="3.6.5.-" evidence="5"/>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94640">
        <property type="protein sequence ID" value="PRC94640"/>
        <property type="gene ID" value="S2091_0643"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031419">
        <property type="term" value="F:cobalamin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047727">
        <property type="term" value="F:isobutyryl-CoA mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004494">
        <property type="term" value="F:methylmalonyl-CoA mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034784">
        <property type="term" value="F:pivalyl-CoA mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006637">
        <property type="term" value="P:acyl-CoA metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02050">
        <property type="entry name" value="IcmF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016176">
        <property type="entry name" value="Cbl-dep_enz_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006158">
        <property type="entry name" value="Cobalamin-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036724">
        <property type="entry name" value="Cobalamin-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033669">
        <property type="entry name" value="IcmF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006099">
        <property type="entry name" value="MeMalonylCoA_mutase_a/b_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006098">
        <property type="entry name" value="MMCoA_mutase_a_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02310">
        <property type="entry name" value="B12-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01642">
        <property type="entry name" value="MM_CoA_mutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51703">
        <property type="entry name" value="SSF51703"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52242">
        <property type="entry name" value="SSF52242"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00641">
        <property type="entry name" value="acid_CoA_mut_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51332">
        <property type="entry name" value="B12_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0143">Chaperone</keyword>
    <keyword evidence="2 5" id="KW-0846">Cobalamin</keyword>
    <keyword evidence="4 5" id="KW-0170">Cobalt</keyword>
    <keyword evidence="5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="B12-binding" evidence="6">
        <location>
            <begin position="18"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="31"/>
        </location>
        <ligand>
            <name>adenosylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:18408"/>
        </ligand>
        <ligandPart>
            <name>Co</name>
            <dbReference type="ChEBI" id="CHEBI:27638"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="215"/>
            <end position="220"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="219"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="244"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="245"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="258"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="261"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="312"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="313"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="359"/>
            <end position="362"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="588"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="623"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="729"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="773"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="822"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="857"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="862"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="974"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="1093"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022628"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC94640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="1094" mass="120654" checksum="648A8D784A7135E5" modified="2018-07-18" version="1">MTDLSITQKLTEYKPVNKVRFVTAASLFDGHDASINIMRRILMANGAEVVHLGHNRSVEDVVTAALQEDAQGIAISSYQGGHVEYFKYMMDLLRARGGAHIKVFGGGGGVIVPDEIADLHAYGVTRIFSPEDGQRMGLVGMILAMIQACDINLSSYAPTSLAALEEPDMGTRQRSLAQLITALENEEVDPALKAALHKQAETKRVPVLGITGTGGAGKSSLTDELIRRIRLDQNDSINIALISIDPSRRKSGGALLGDRIRMNAIMPWGLSTEPRVFMRSLATREAGSEISPALPDVIAACKIAGFDLVMVETSGIGQGDAAIVQHVDTSMYVMTPEFGAASQLEKIDMLDFADFVAINKFDRKGALDALRDVSKQVQRNHELWTLKPEQMPVYGTQASRFNDDGVTALYQGLLAKLVAQGMPLHPSKLPVVDSRFSSGKNVIVPPARSRYLAEISDCVRHYHRSTAKQVALAREKQQLQAAAKMLMKAGKSVDVEELVQERDNHLDANSKQLLASWPDMLAAYSGAEYVVKIRDKEIRTNLIFDTLSGTKIRKVALPKFVDHGEILRWLMLENVPGSFPFTAGVFAFKREGEDPTRMFAGEGDPFRTNRRFKLVSQGMPAKRLSTAFDSVTLYGADPAVRPDIYGKVGNSGVSVATLDDMKVLYDGFDLCDPATSVSMTINGPAPTILAFFMNTAIDQQMDKFRTDNKREPSADEAAKIKAWVLQNVRGTVQADILKEDQGQNTCIFSTEFSLKVMGDIQEYFVHHQVRNFYSVSISGYHIAEAGANPISQLAFTLSNGFTFVEAYLARGMHIDDFAANLSFFFSNGMDPEYTVLGRVARRIWAVAMRDKYGANDRSQKLKYHIQTSGRSLHAQEIDFNDIRTTLQALIAIYDNCNSLHTNAYDEAITTPTDDSVRRALAIQLIINREWGLAKNENPIQGSFIIEELTDIVEEAVLKEFERIAERGGVLGAMETGYQRGKIQEESMHYEHMKHDGSLPIIGVNTFRNPKAGDTPQKIELARSTDEEKQSQLHRLAEFHAKHANEAPAALAALQQAAILDENVFAQLMSAARVCSLGQITTALFEVGGQYRRNM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3X7</accession>
    <name>A0A2S9H3X7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Pyruvate ferredoxin/flavodoxin oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_0636</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94633">
        <property type="protein sequence ID" value="PRC94633"/>
        <property type="gene ID" value="S2091_0636"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016903">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07034">
        <property type="entry name" value="TPP_PYR_PFOR_IOR-alpha_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.920.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019752">
        <property type="entry name" value="Pyrv/ketoisovalerate_OxRed_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002880">
        <property type="entry name" value="Pyrv_Fd/Flavodoxin_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002869">
        <property type="entry name" value="Pyrv_flavodox_OxRed_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011766">
        <property type="entry name" value="TPP_enzyme-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01558">
        <property type="entry name" value="POR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02775">
        <property type="entry name" value="TPP_enzyme_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="SSF52922"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53323">
        <property type="entry name" value="SSF53323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="4" id="KW-0249">Electron transport</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="8">
        <location>
            <begin position="649"/>
            <end position="679"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC94633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="1176" mass="128135" checksum="19305DCF03C5BDA8" modified="2018-07-18" version="1">MSSSVKQESAGSSLAPVSLDDKYTANSGMIYLSGVQALVRLPLIQRQRDLAAGLNTAGFISGYRGSPLGGLDQTLWKTKKFLETQHVKFVPGVNEDLAATAVWGTQQVDLIGPSKYDGVFGMWYGKGPGVDRCGDVFKHMNHAGTSKHGGVILVAGDDHGAYSSTLPHQSDHMFSAAMIPMLYPSNVQEYLDLGLHAWAMSRFSGCVVGFKALADTVESSASIDADPFRLQITIPTDFAMPVGGLNARLTTETLGIEARKQEALMQDYKIYAALAYARANKLNHTTIDSPTAKLGIIASGKSYLDVLEALEGLGIDEKFAAEIGIRLFKVSMPWPLEPDGVREFARGLDEILVVEEKRQIVEYQLKEQLYNWRDDVRPRVIGKFDEKGEWVQPRGDWLLTSKADFSVAQIARVIAARIARFHTSDLIKARLAFLEAKDVVLKKTVDTPTRPAYYCSGCPHNTSTKVPEGSLALAGIGCHVMATAIYPDHNKTTTHMGGEGAPWIGQAPFSTLPHVFANLGDGTYFHSGYLAIRASVAAKVNITYKILYNDAVAMTGGQPVDGIISVPMMAQQMAAEGVKRIALVTEDLSRYADRSNLPGIITLHDRKDMDAVQRELREFIGASVIIYDQTCAAEKRRRRKKGQFPDPEKRLVINDAVCEGCGDCGVQSNCTSIVPLETEFGRKRAIDQSTCNKDYSCVKGFCPSFVTVEGGKLKKSKAGTAKQDDFPALAEPLLPSCDVAYNILLNGIGGTGVITIGALIGMAAHLEGKGVSVLDMTGMSQKNGSVTSHIRITASPGQLNAQRIATGEADLVLGCDVLTTGAFDAISKMRPGRTRAVVNIDQTPIGTFAQQPDWEFPLQAVQALIMESVDGNADFIDATKLATALMGDSIATNLFMLGFAYQKGAIPISEAALLRAIELNGVAIESNKKSFLWGRRAAVDFARVEKIALPSQPIVLRMPESLDKLIQRRVAVLTDYQNSAYAQQYQTLVTQVKQAEEKLGKGNKLAMAVAKSAFKLMAYKDEYEVARLYTNGEFADKLKAQFEGDFSVKFNLAPPLFSKKDGAGHLVKAQYGSWMWQAFKVLAKFKTLRGTALDIFGYTDERKSERKLSADYQQMMLELSANLTADNLDTAIALANLPEKVRGFGHVKEQAMSEYYQQVAVLKNGCGTRIVELARV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H478</accession>
    <name>A0A2S9H478_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0781</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94778">
        <property type="protein sequence ID" value="PRC94778"/>
        <property type="gene ID" value="S2091_0781"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="86" mass="10070" checksum="8AFF1C8A303F1AF1" modified="2018-07-18" version="1">MLRRGAVANLRRLHLFGNYLKHHTNISHSKFFTSQMLAITLLQCKVISHEILLKYIGLLTHLRLETIKHVIFGRFALNRYNTVTLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4C0</accession>
    <name>A0A2S9H4C0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0020</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94825">
        <property type="protein sequence ID" value="PRC94825"/>
        <property type="gene ID" value="S2091_0020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="49" mass="5406" checksum="298067ABBDD4FF07" modified="2018-07-18" version="1">MDKAVFDESGIHIVAAFLDQDECSLLNSAISNLNTESVGTRNLLNYSWC</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4E4</accession>
    <name>A0A2S9H4E4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Bacterial extracellular solute-binding protein, family 5 Middle</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0032</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94837">
        <property type="protein sequence ID" value="PRC94837"/>
        <property type="gene ID" value="S2091_0032"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030288">
        <property type="term" value="C:outer membrane-bounded periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030678">
        <property type="entry name" value="Peptide/Ni-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039424">
        <property type="entry name" value="SBP_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000914">
        <property type="entry name" value="SBP_5_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30290">
        <property type="entry name" value="PTHR30290"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00496">
        <property type="entry name" value="SBP_bac_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002741">
        <property type="entry name" value="MppA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015549319" evidence="1">
        <location>
            <begin position="29"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="domain" description="SBP_bac_5" evidence="2">
        <location>
            <begin position="77"/>
            <end position="486"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="568" mass="64571" checksum="F7D6E9CD31BDA6A0" modified="2018-07-18" version="1">MKHRLFLSYALSFSLLSALFLSSSYAQAPVKTLRVLLVSSEAALDPAQASDLQSISINENIFDAMLRYDYLARPVKLQPNTLIAMPEISDHGTRYVMKIKPGILFTPDAAFKGQARELTAQDYVYSLQRLLDPTIKSPWRYLVENKFDDKQGIVALDRYTLQLRLKKPDPHFLFQLAMPATAAVAREVVEAYPGQAGNHPIGTGPFKMGQWQRSFKIELLANPAYHGQFSTSALDSEIARNLLGKKLPRVDRVEVIIMEEHQSRVLGFMRGEVDYLEQIPPPLSGMMLIDGKLKPELIKQGIQLSLFSPLQTYYMWMNMEDPVIGGYSLEKIALRRAIAMSYNSEEDIRLLEQGLAIPAQTPLPPNVLGYDASYRSPVAFDVPLANALLDKFGYQQRDAEGYRKLPNGQPLHLIMHSLASITGRLRDEVWRKNLDAIGIRISFKTDKQAEILRAARQGKVQMTEANWIADFPDGDNFYQLLYGPNSTAANYAHFNLPAYNQLYLQSSALADSPERLRIYHDMAQLIHAYSPWVIRIHPLSADVIQPWLKNYQRHPVEFTNWRYLDVVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4M1</accession>
    <name>A0A2S9H4M1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Amidases related to nicotinamidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0130</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94935">
        <property type="protein sequence ID" value="PRC94935"/>
        <property type="gene ID" value="S2091_0130"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.850">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000868">
        <property type="entry name" value="Isochorismatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036380">
        <property type="entry name" value="Isochorismatase-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00857">
        <property type="entry name" value="Isochorismatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52499">
        <property type="entry name" value="SSF52499"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Isochorismatase" evidence="1">
        <location>
            <begin position="11"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="187" mass="20373" checksum="5EA885BFC7DD7FBD" modified="2018-07-18" version="1">MTITKLDDTCALIVIDLQKGIVGLPTAHPSSEIVQRSSQLARAFRARALPVVLVNVAGRAPGRTDSGPPKFVFPDNWTVLVPELEQQPNDHLVTKNRIGAFLGTDLDAYLRQRGVTQIILTGISTSSGVEATARSAYDLGYNVVFVADAMTDLDPDMHRHSIEKVFPKLGETGKTDDLLMLLNSHKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4P3</accession>
    <name>A0A2S9H4P3_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ribonuclease VapC</fullName>
            <shortName evidence="5">RNase VapC</shortName>
            <ecNumber evidence="5">3.1.-.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Toxin VapC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">vapC</name>
        <name evidence="7" type="ORF">S2091_0144</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Toxic component of a toxin-antitoxin (TA) system. An RNase.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the PINc/VapC protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="5"/>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94949">
        <property type="protein sequence ID" value="PRC94949"/>
        <property type="gene ID" value="S2091_0144"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004540">
        <property type="term" value="F:ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090729">
        <property type="term" value="F:toxin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00265">
        <property type="entry name" value="VapC_Nob1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002716">
        <property type="entry name" value="PIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022907">
        <property type="entry name" value="VapC_family"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01850">
        <property type="entry name" value="PIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="SSF88723"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 5" id="KW-0540">Nuclease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0800">Toxin</keyword>
    <keyword evidence="1 5" id="KW-1277">Toxin-antitoxin system</keyword>
    <feature type="domain" description="PINc" evidence="6">
        <location>
            <begin position="4"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="7"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="98"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC94949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="137" mass="15190" checksum="E4AD2DB307B361D8" modified="2018-07-18" version="1">MLKYLLDTNIVIYVLKRRPLELLQVFNNHTNHMAISAITLGELLHGVEKSSQPVANLNVVEDFCSRVTVLPYAAKAAQHYGAIRAALEKIGQPIGVNDFHIAAHARSEGLILVTNNIKEFVKVPALQLENWLAAPEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4V6</accession>
    <name>A0A2S9H4V6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0192</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94997">
        <property type="protein sequence ID" value="PRC94997"/>
        <property type="gene ID" value="S2091_0192"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="81"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="108"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="138" mass="14633" checksum="7CACBD96D213D1A0" modified="2018-07-18" version="1">MRGAGGTSGGIGQFFIGLFMMCGGFYMLLNDVIVQSSFGMGMGLYGFAAMGGYYSITSGMIMIPFILGVGMIFYNIKNLLGWLLAIGSLAALLFGVISSIHFSLRSMSLFDLIVILVLAVGGLGLFLRSLQEAKQAES</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4Z0</accession>
    <name>A0A2S9H4Z0_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Type II secretion system protein H</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">General secretion pathway protein H</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">S2091_0250</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95055">
        <property type="protein sequence ID" value="PRC95055"/>
        <property type="gene ID" value="S2091_0250"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015627">
        <property type="term" value="C:type II protein secretion system complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015628">
        <property type="term" value="P:protein secretion by the type II secretion system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022346">
        <property type="entry name" value="T2SS_GspH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12019">
        <property type="entry name" value="GspH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0488">Methylation</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="domain" description="GspH" evidence="12">
        <location>
            <begin position="46"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004377"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF12019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PRC95055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="174" mass="19092" checksum="20FE6045EFFE4DDB" modified="2018-07-18" version="1">MKISIVKQNGFSLVEVMFTLTIAVIVIGIGAPSFNDFIQQTRLILATNSLHSAINLTRSEAIKRNGRVDLVSINGNWKNGWEIKSANTIISTHEALHPTISISSGFFDNSTQYIAYNGTGRTRTNVSSKQPQAGTISIKVNKSVRRIKIDFLGRARVCNPAEEKLTCTTGPNEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H511</accession>
    <name>A0A2S9H511_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CheW-like domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0264</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95069">
        <property type="protein sequence ID" value="PRC95069"/>
        <property type="gene ID" value="S2091_0264"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039315">
        <property type="entry name" value="CheW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036061">
        <property type="entry name" value="CheW-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002545">
        <property type="entry name" value="CheW-lke_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22617">
        <property type="entry name" value="PTHR22617"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01584">
        <property type="entry name" value="CheW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00260">
        <property type="entry name" value="CheW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50341">
        <property type="entry name" value="SSF50341"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50851">
        <property type="entry name" value="CHEW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CheW-like" evidence="1">
        <location>
            <begin position="45"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC95069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="189" mass="21119" checksum="81E4666ACC993D6A" modified="2018-07-18" version="1">MNQVNTAKLDKPIEDKRGERRERLREFQSQLLERMQAARASDVISSNQLGVMIGQTRYLLNLREAGEIVSIGQISHVPLTRDWYLGLLNIRGNLIGVVDIQRFQGQPGAEINPDCRVIAFSAGLAFNAGLLVTKVLGLRNVAEMTVQQNPADGDSAWLQQSYLDSNNQTWFELSLTNLIQDGDFLHIGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H523</accession>
    <name>A0A2S9H523_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Addiction module toxin, RelE/StbE family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0236</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95041">
        <property type="protein sequence ID" value="PRC95041"/>
        <property type="gene ID" value="S2091_0236"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2310.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007712">
        <property type="entry name" value="RelE/ParE_toxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035093">
        <property type="entry name" value="RelE/ParE_toxin_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05016">
        <property type="entry name" value="ParE_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02385">
        <property type="entry name" value="RelE_StbE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-1277">Toxin-antitoxin system</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC95041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="60" mass="6782" checksum="970699B95A345EF0" modified="2018-07-18" version="1">MGDMLIQKAAQLDQHPTLGRVGRVKGTRELVVHPNCILIYRIVGKIAEVLRVKHVAQQWP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H526</accession>
    <name>A0A2S9H526_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0285</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95090">
        <property type="protein sequence ID" value="PRC95090"/>
        <property type="gene ID" value="S2091_0285"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009305">
        <property type="entry name" value="Mpo1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06127">
        <property type="entry name" value="DUF962"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="29"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC95090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="103" mass="12227" checksum="6017CFE1E9AE6197" modified="2018-07-18" version="1">MNNATRFNSFADFYPFYLNEHCNVISRRLHVIGTSCVLLLSLTSIVTQHWALLWLLPVLGYSFAWVGHYVFEKNRPATFKHPLYSLMGDFKMWWQVVTQQLNW</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H537</accession>
    <name>A0A2S9H537_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Outer membrane efflux protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_0272</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95077">
        <property type="protein sequence ID" value="PRC95077"/>
        <property type="gene ID" value="S2091_0272"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015562">
        <property type="term" value="F:efflux transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003423">
        <property type="entry name" value="OMP_efflux"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02321">
        <property type="entry name" value="OEP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015523442" evidence="3">
        <location>
            <begin position="23"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="190"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC95077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="434" mass="47809" checksum="FB9D6194D62328A4" modified="2018-07-18" version="1">MRLLHVPLTVAALLYFPFSAHAEISTTPLESTQTESPTITLAHAWQLAEQANPELRQALAQRDAIEGDVTDASSLLWNNPNLTSSAVRRTLPETGSETKREWSAGIEQTFEIAGQQGLRRSASLQQQEAFNASLDFLRMEVRAEVERRFVKVLALQEHIATENTSQQLIANTAAYVQKRITAGEDSRLDGNLANVEAARARNQIDTLKEQLLEARTELASVLQLPFNELPLVQGELSSSTSTGTLEALLASAATQPLVRSLELKELAAKSRLSLERASRYPDVTLGLSTGKEGAVSERERVTTLSITLPLPLFRRNASGIGRASTELTQAQIERQTTNRNTVNNITSLWQKQQSLVARLSSLQQNLLPALNDNQSLSLKSLQAGEIDLFQLLLVNRQELDGRRDLINAQAELRLTDIALKQAAGWNPMSANPRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H581</accession>
    <name>A0A2S9H581_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">3-oxoadipyl-CoA thiolase</fullName>
            <ecNumber evidence="4">2.3.1.174</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">S2091_0334</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>acetyl-CoA + succinyl-CoA = 3-oxoadipyl-CoA + CoA</text>
            <dbReference type="Rhea" id="RHEA:19481"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:57292"/>
            <dbReference type="ChEBI" id="CHEBI:57348"/>
            <dbReference type="EC" id="2.3.1.174"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Aromatic compound metabolism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the thiolase-like superfamily. Thiolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.174" evidence="4"/>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95139">
        <property type="protein sequence ID" value="PRC95139"/>
        <property type="gene ID" value="S2091_0334"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00246"/>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033812">
        <property type="term" value="F:3-oxoadipyl-CoA thiolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019619">
        <property type="term" value="P:3,4-dihydroxybenzoate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00751">
        <property type="entry name" value="thiolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012793">
        <property type="entry name" value="PcaF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002155">
        <property type="entry name" value="Thiolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020615">
        <property type="entry name" value="Thiolase_acyl_enz_int_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020610">
        <property type="entry name" value="Thiolase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020617">
        <property type="entry name" value="Thiolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020613">
        <property type="entry name" value="Thiolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020616">
        <property type="entry name" value="Thiolase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02803">
        <property type="entry name" value="Thiolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00108">
        <property type="entry name" value="Thiolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000429">
        <property type="entry name" value="Ac-CoA_Ac_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01930">
        <property type="entry name" value="AcCoA-C-Actrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02430">
        <property type="entry name" value="pcaF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00098">
        <property type="entry name" value="THIOLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00737">
        <property type="entry name" value="THIOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00099">
        <property type="entry name" value="THIOLASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thiolase_N" evidence="8">
        <location>
            <begin position="5"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="domain" description="Thiolase_C" evidence="9">
        <location>
            <begin position="277"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-thioester intermediate" evidence="6">
        <location>
            <position position="90"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="356"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000429-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC95139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="400" mass="42091" checksum="8FCD139E148777B6" modified="2018-07-18" version="1">MNQAYICDALRTPIGRYGGALKELRADDLAAIPLRALMARHPQMDWAAVQDVILGCANQAGEDNRNVARMSALLAGFPLEVAGSTINRLCGSGMDAVGTCARAIRSGDTELMIAGGVESMTRAPFVMSKADSAFSRKAEIFDTTMGWRFVNQLMQAQYGIDSMPQTAENVAAEYGISREDQDLFAVASQNKAAAAQLSGLFAQEITPVIIDQKKGQPIVVHQDEHPRATSMEALGKLKGVVHSNGSVTAGNASGINDGACALLLASENAVKQHGLVPRARIVGMAVAGVAPRLMGIGPVPATQKLLAQLGMTLDQMDVIELNEAFAAQGLAVLRLLGLQDNDPRVNPNGGAIALGHPLGMSGARLVTTAMYQLQRTGGRYALCTMCIGVGQGIAIVIERV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5F8</accession>
    <name>A0A2S9H5F8_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Exodeoxyribonuclease I</fullName>
            <ecNumber evidence="2">3.1.11.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">DNA deoxyribophosphodiesterase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">S2091_0301</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates.</text>
            <dbReference type="EC" id="3.1.11.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="12">Binds 2 Mg(2+) ions per monomer.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.11.1" evidence="2"/>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95106">
        <property type="protein sequence ID" value="PRC95106"/>
        <property type="gene ID" value="S2091_0301"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000175">
        <property type="term" value="F:3'-5'-exoribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008852">
        <property type="term" value="F:exodeoxyribonuclease I activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023607">
        <property type="entry name" value="Exodeoxyribonuclease_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034748">
        <property type="entry name" value="EXOI_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034747">
        <property type="entry name" value="EXOI_SH3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038649">
        <property type="entry name" value="EXOI_SH3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013620">
        <property type="entry name" value="Exonuc_1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013520">
        <property type="entry name" value="Exonuclease_RNaseT/DNA_pol3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022894">
        <property type="entry name" value="Oligoribonuclease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11046">
        <property type="entry name" value="PTHR11046"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08411">
        <property type="entry name" value="Exonuc_X-T_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00929">
        <property type="entry name" value="RNase_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000977">
        <property type="entry name" value="Exodeoxyribonuclease_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00479">
        <property type="entry name" value="EXOIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51785">
        <property type="entry name" value="EXOI_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51784">
        <property type="entry name" value="EXOI_SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0227">DNA damage</keyword>
    <keyword evidence="9" id="KW-0234">DNA repair</keyword>
    <keyword evidence="8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="15" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-0540">Nuclease</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ExoI SH3-like" evidence="13">
        <location>
            <begin position="197"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="domain" description="ExoI C-terminal" evidence="14">
        <location>
            <begin position="354"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="10"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11 12">
        <location>
            <position position="12"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="160"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="181"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00031220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000977-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR000977-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="PRC95106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="477" mass="54528" checksum="AB7F73FDAF80CDBA" modified="2018-07-18" version="1">MQAHTFLWHDYETFGANTRRDRPAQFAAIRTDADLNEVGEPMMWYCLPAPDFLPEPQACLITGITPQMCLERGIPEYQFAQQINQQFSEPGTIGVGYNTIRFDDEITRFMLWRNLLEPYAREWQNQCGRWDILDMLRTTYALRPEGINWPRNDEGKVSFKLEHLCAANGIAHESAHDALSDVRATIALAKLVRKVQPKLFDFCFSLHKKDKVAAEIGLPEQRPFLHVTGMIPVENGCLCIAWPLAPHPTNKNEVISWNLAYDPRELLGMNAEAIRLRMFSKADALPEGVTRLPIKGIHLNKSPIVIGNLKTLQPAMAEQWGISVELAMQHAEYALALPDLNAVWQQVFKRENNEAQDVDQDLYNGFIGNTDRRSLQSLVTYSGEKLARTVTEFQDARLDELLFRYRARNFPETLSEQEAERWDTLRASRFFDGSANALTVDAYFAEIDRLSEQASEQDEEILASLYDYAEQIVPVQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5M1</accession>
    <name>A0A2S9H5M1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CheW-like domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0371</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95176">
        <property type="protein sequence ID" value="PRC95176"/>
        <property type="gene ID" value="S2091_0371"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036061">
        <property type="entry name" value="CheW-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002545">
        <property type="entry name" value="CheW-lke_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01584">
        <property type="entry name" value="CheW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50341">
        <property type="entry name" value="SSF50341"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50851">
        <property type="entry name" value="CHEW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CheW-like" evidence="1">
        <location>
            <begin position="38"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC95176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="195" mass="21501" checksum="BEF9AF968E93B896" modified="2018-07-18" version="1">MNQAYRSNSPSKSADALAMRREFDLGFAQAPHVQKEALLNFLGIRLGDDAFAIRVSDIAGLHADRRIMPMPSPVPALLGVAGFRGLIAPVYDLAALLGYKCKTPPRWLILIRLGEPVALAFEHFEVHFSAEPGSIISAPQLAVSIPDNARVHRYDAVRADDAIRPIIHLQSLLAPILEPKQRSLNLSLQQRRKES</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5N8</accession>
    <name>A0A2S9H5N8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0438</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95243">
        <property type="protein sequence ID" value="PRC95243"/>
        <property type="gene ID" value="S2091_0438"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd04221">
        <property type="entry name" value="MauL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034242">
        <property type="entry name" value="MauL"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="SSF49503"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC95243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="231" mass="25073" checksum="DEE7D676ECAEA2D8" modified="2018-07-18" version="1">MENQLFSGIHSIAPKVRLFSLFGAICLTCLVCLSPSPLLAATLSVQVTDSLGAPLEDVVVYAEPVSGEKLPKSVRAVEIAQKHRQFVPLVTVVQAGTEISFPNLDTVKHHVYSFSPTKYFDLPLYSGMAAKPQLFDLPGTVVLGCNIHDKMVAYVQVVNTPYFAKTDATGKVKLNGIIPGKYQLKAWHFMLPPLAQVVTQPINIVGDENTASFKLNVKQAKPATEDSTPIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GS78</accession>
    <name>A0A2S9GS78_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4709</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000049">
        <property type="protein sequence ID" value="PRC90582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90582">
        <property type="protein sequence ID" value="PRC90582"/>
        <property type="gene ID" value="S2091_4709"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC90582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="283" mass="31464" checksum="CC13C58E89760507" modified="2018-07-18" version="1">MQAAQRIRHLFVLLVISPICLCQGAEKIVLPLKFEQNIPVVTLHIDGRDLQFTLDTGASDALYLDPDIESAIPEVTRTGKIVKSFDLSGKVVENDEILIADLVVDGMHFGQTRGRMHTPWGITAEGSSGPPHRSVIGLQFFENKKVLFDYSGGRIIIWSAETSIPADVVGWTILPFERGHEGVIVAMRSTNRSYRLVLDSPSTISIVKSQSVEQSESTTHCNIHFHPGEECRKISLTLLSGSEFSPILMEMPEKFHADGIIGREFFDRYKVYLDLAGSSIRVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GS86</accession>
    <name>A0A2S9GS86_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4711</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000049">
        <property type="protein sequence ID" value="PRC90584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90584">
        <property type="protein sequence ID" value="PRC90584"/>
        <property type="gene ID" value="S2091_4711"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC90584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="590" mass="63608" checksum="1D125C62E1601DE8" modified="2018-07-18" version="1">MIITVFLKVRGGNLSKVIATAVVSIVCISTASLAQSANNDRDAIAARYLSEAGSLASKAEPSEIAKHQYLLTKIAEYQVKAGDEGGARETLKIARDFMLKTKSDHVGDGPYVSLATANVVAGDAAAAVDIIFSDPMDSNHAHGLFQISREQVLLGNLDQAQQTITAIGELANRREGWQRNADLKWHDEALRLVAGSYAAAEKFTDASVAINSIQDVGIKAEVLGSTALVATRAGKLNLAREFFDQAIAFAIQIGTPTDPLHIMSREFVLNEIAVNAATAGDRKNAFRLVDLQGKNCRHRDDTSHEKGVDAEELKRTSSLPACGDRDLALAFLVQGFSGNDDLSNAEKLASTLPIGYPHDMAQSALSGAQARTNAIEAAIVTAQGISMSVLRDKALLRITEIAAKKEKHILAKKSISHIDNVGERARAMLIDAIQLVSAGKLDEAWILADEVQEMATFQMNYNQRIDAISTAAAIFSLRSLADAETLLGKLNECERNTGFLRSAKILANHGRHDEAISALRLAFNSVPETCSNRGMKLQFVARERVRNGDQTQAAEDIAKLADRLVRAEAFLGLASGLWSEPEMPLMTPGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSA5</accession>
    <name>A0A2S9GSA5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4714</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000051">
        <property type="protein sequence ID" value="PRC90576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90576">
        <property type="protein sequence ID" value="PRC90576"/>
        <property type="gene ID" value="S2091_4714"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC90576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="68" mass="6896" checksum="5D29020AD0E3997D" modified="2018-07-18" version="1">MVQVPGATKVTVLPDTVQTDVVAEVNTTPKLALLVADTAKGAAPYVLPANVAKLIVCASFATVIDCAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSN9</accession>
    <name>A0A2S9GSN9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Beta-glucanase/Beta-glucan synthetase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_4601</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000038">
        <property type="protein sequence ID" value="PRC90708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90708">
        <property type="protein sequence ID" value="PRC90708"/>
        <property type="gene ID" value="S2091_4601"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000757">
        <property type="entry name" value="GH16"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00722">
        <property type="entry name" value="Glyco_hydro_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="SSF49899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51762">
        <property type="entry name" value="GH16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015709442" evidence="1">
        <location>
            <begin position="21"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="domain" description="GH16" evidence="2">
        <location>
            <begin position="32"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC90708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="296" mass="32316" checksum="F80C6998ABCADBC4" modified="2018-07-18" version="1">MTITFIRKHTSFLLTALLLASCGGGGGSGSNSGSANNSTPPIVPVASDWQLIWSDEFNNTSLDSSKWSLESGGDGWGNNELEYYTAGDNASVSDGYLTITARQQSYGGLNYTSSRLITKGKAYWTYGKVEARIKLPYGQGMWPAFWMLGEDIDSVGFPGSGEIDIMEMVGGKDDDGSNRNSVIWGSLHRPNLDPNPASDVKSFTASYRNPGDINFNNDFHVFGIEWNATTVIYSVDGNVYQTVDISSNTDGFDVFKKPFFIVLNLAVGGDWPGAPDLTTVWPAQMQVDWVRVYQKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSU5</accession>
    <name>A0A2S9GSU5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Cytochrome C oxidase, cbb3-type, subunit III</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_4457</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000035">
        <property type="protein sequence ID" value="PRC90794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90794">
        <property type="protein sequence ID" value="PRC90794"/>
        <property type="gene ID" value="S2091_4457"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002323">
        <property type="entry name" value="Cyt_CIE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40942">
        <property type="entry name" value="PTHR40942"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13442">
        <property type="entry name" value="Cytochrome_CBB3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00607">
        <property type="entry name" value="CYTCHROMECIE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0249">Electron transport</keyword>
    <keyword evidence="2 6" id="KW-0349">Heme</keyword>
    <keyword evidence="5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="18"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="8">
        <location>
            <begin position="79"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC90794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="181" mass="18676" checksum="8FC1080905F7CD8B" modified="2018-07-18" version="1">MSDAHDQHESAIKTPKQLVVAVLAAILVPIICIVMLVQFVTSGNLPNAGSSAQTPEAIAARIQPVSDVGYTFKDASAPKQLLSGEEIYKTTCVACHGAGVAGAPKFGDLAAWAPRLKEGYDKVVGYALHGLNAMPARGGNADLDDVEVARAVVYMANHSGASFKEPEVPAPAPAAETAAAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSV8</accession>
    <name>A0A2S9GSV8_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Flagellar hook-basal body complex protein FliE</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">fliE</name>
        <name evidence="4" type="ORF">S2091_4524</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 3">Bacterial flagellum basal body</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the FliE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000036">
        <property type="protein sequence ID" value="PRC90776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90776">
        <property type="protein sequence ID" value="PRC90776"/>
        <property type="gene ID" value="S2091_4524"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009425">
        <property type="term" value="C:bacterial-type flagellum basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003774">
        <property type="term" value="F:cytoskeletal motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071973">
        <property type="term" value="P:bacterial-type flagellum-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00724">
        <property type="entry name" value="FliE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001624">
        <property type="entry name" value="FliE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34653">
        <property type="entry name" value="PTHR34653"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02049">
        <property type="entry name" value="FliE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01006">
        <property type="entry name" value="FLGHOOKFLIE"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00205">
        <property type="entry name" value="fliE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0975">Bacterial flagellum</keyword>
    <keyword evidence="4" id="KW-0966">Cell projection</keyword>
    <keyword evidence="4" id="KW-0969">Cilium</keyword>
    <keyword evidence="4" id="KW-0282">Flagellum</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC90776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="135" mass="13828" checksum="4CAE206FCA63509E" modified="2018-07-18" version="1">MSVGGVGGVGISSSQIDSMLTMLRNTAAQAAPPSTMSVGNVVVPTSSDGTNGVSGTSGTTATVSFADALKSSLNQVNQVQEKAQKLGDQFLLGDDKVSISDVMIAGQKASISLQTTVQVRNKMVAAYNDIMNMQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSW6</accession>
    <name>A0A2S9GSW6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4477</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000035">
        <property type="protein sequence ID" value="PRC90814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90814">
        <property type="protein sequence ID" value="PRC90814"/>
        <property type="gene ID" value="S2091_4477"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023614">
        <property type="entry name" value="Porin_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015679472" evidence="1">
        <location>
            <begin position="29"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="395" mass="44165" checksum="A0706F98EEFE4282" modified="2018-07-18" version="1">MKYHSFLTKNLIAVSLLASSALSIHAQAQTTDVPKVAADSPPLIVDSPYSYSGFASLIGGQSSGRCQPTGMAQDTTSCTRYVGDWGHDGIYNNNFSIAQESRIGVQFTDKFTHDLSGTIQLTARPIRDEHLNLEWAYLTYKPDSSWTIYIGRKRLPLFYYSDIQDIGYAYNTIRLDGSIYGWEVTNYNGISVDYSFNVADWDVRAEMLVGTEDAKNNAYERLFYATPQDIGWHRIVGMSFDFSHDWLTGRLGYEHSDYSQFDAVTGAVPLFTGGYQASQSFLDASLTADLNDWILHTEFGDAHRLGIGALARFYSVSAGYRMGKFLPTIQYGTYRESTPFANYNDGKFQTAVLALRYDFAKNMDFKVQLDRAIDNGQPPLQGSAYLVSAGIDIVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSX6</accession>
    <name>A0A2S9GSX6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">RDD family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_4459</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000035">
        <property type="protein sequence ID" value="PRC90796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90796">
        <property type="protein sequence ID" value="PRC90796"/>
        <property type="gene ID" value="S2091_4459"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010432">
        <property type="entry name" value="RDD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06271">
        <property type="entry name" value="RDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="43"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="98"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="141"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="domain" description="RDD" evidence="6">
        <location>
            <begin position="8"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF06271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC90796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="199" mass="22831" checksum="9A05ABF2F268F2C0" modified="2018-07-18" version="1">MNEENLEYSGFWRRAVAHGIDALFCVLFFWITDALNGGHKELAVAIAVLQGSTFYLYTFYCHAKFGKTIGKRIMGLKVLNIEGSPISFLQSFKRNIPLFIESLPWIISTYFVISNIPADQFHNLFLQPKAYRQLEDSMRPIWYFPVQMVMAVFVAADIITMLISRKRQTLHDMIGGTIVVHQDELGRAAHVDENPQRIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSZ4</accession>
    <name>A0A2S9GSZ4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="13">OmpA family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">S2091_4479</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell outer membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000035">
        <property type="protein sequence ID" value="PRC90816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90816">
        <property type="protein sequence ID" value="PRC90816"/>
        <property type="gene ID" value="S2091_4479"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046930">
        <property type="term" value="C:pore complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015288">
        <property type="term" value="F:porin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006811">
        <property type="term" value="P:ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07185">
        <property type="entry name" value="OmpA_C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011250">
        <property type="entry name" value="OMP/PagP_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027385">
        <property type="entry name" value="OMP_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006664">
        <property type="entry name" value="OMP_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006665">
        <property type="entry name" value="OmpA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006690">
        <property type="entry name" value="OMPA-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036737">
        <property type="entry name" value="OmpA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13505">
        <property type="entry name" value="OMP_b-brl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00691">
        <property type="entry name" value="OmpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01021">
        <property type="entry name" value="OMPADOMAIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103088">
        <property type="entry name" value="SSF103088"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56925">
        <property type="entry name" value="SSF56925"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01068">
        <property type="entry name" value="OMPA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51123">
        <property type="entry name" value="OMPA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0626">Porin</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1134">Transmembrane beta strand</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015773654" evidence="11">
        <location>
            <begin position="25"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="domain" description="OmpA-like" evidence="12">
        <location>
            <begin position="228"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PRC90816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="355" mass="38643" checksum="18DF57AF55B5C6C7" modified="2018-07-18" version="1">MNNFKQISLAAAILCCATSGSVFAQAAQPAQVVPIFDYNPSWYIAPTVNGMYPDTGFGVEQHGEGGGLRLGKPISESWDIQLGTSYARARNNGTTYQQNLLGVDALYMFSRDTFRPFLLVGAGAQEDRLSSSVAGTSGYAPYVNAGLGFQVSLNDQWSLQADFRRVHGYLRDNDFSISRNSNNYLMVGINYAFDKSPTRPVAVAPTPEPAPIIAVITPPPAPTPPPAPRFEKISLSSTELFSFDKSDLKMPQPKLDEIAAALNKNTQVNNVVISGYTDRIGSDKYNQKLSERRANAVKDYLVGKGIDAGRLSAVGKGKSDPVVVCTQTKRPALIDCLEPNRRVEVEQITIEQRVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GT65</accession>
    <name>A0A2S9GT65_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Metallo-beta-lactamase superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4384</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000033">
        <property type="protein sequence ID" value="PRC90891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90891">
        <property type="protein sequence ID" value="PRC90891"/>
        <property type="gene ID" value="S2091_4384"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lactamase_B" evidence="1">
        <location>
            <begin position="33"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="320" mass="35129" checksum="2D3BAD47530B300A" modified="2018-07-18" version="1">MTKAFASQADLDEKKISFTQLSENAWAYTAEGDPNSGVIIGDDSVLIIDTTATPAMAQDLIARIRTITDKPIKHIVLSHYHAVRVLGASAYLKEGLEQIIASRGTFDLIVERGTADMKSEIERFPRLFAGAESIPGLTWPTLVFESEITLFLGALEVKIMHLGAGHTKGDTVVWIPSQKILFSGDLVEFGAACYCGDAQLGEWPMTLDALSNLSAEKLVPGRGPALLTPNEVNIGLNYTKHFVITLLQQGYAAVEQNLDLKNAMALTRKVMDPLFGHVFIYEHCLPFGVSRAFDEASGILHPRIWTAQRDQEMWAALQSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GT79</accession>
    <name>A0A2S9GT79_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4406</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000033">
        <property type="protein sequence ID" value="PRC90913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90913">
        <property type="protein sequence ID" value="PRC90913"/>
        <property type="gene ID" value="S2091_4406"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC90913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="498" mass="51459" checksum="4EC6B3E47CF9EE98" modified="2018-07-18" version="1">MFNFHGRHLSQHSTLITAFISFIFCLILSACSGSSSSSGSPVTSGSSGSTPTPVTFNAAAAAVHTNLSQEAPHFNNSSVVTALNFKNYIRHFFPKNLSLYNEAIAADLGLSVIWDPENGSPPLNSDFSMVNQYMGGGFTPVGSTNNCTNGTITIPCNESLKNYMGQALDPNFQNGNGASTTIFGRLNNALTTICALSNLLTAAETDTDGLPVAGPLNVALPSDTTNTIYQPISSGGCGIPSSQAGQTLAVVVTAVSSSNYTKMLTTTPASNAVWLKLNASAGTLNVMTLEDQRPQGRYAIDRAIAVITGINTPGSGTTAFEYINMGSNVAASDSCYANGIWQCDFEFHRVYIDEANNVAYLISNNGSPGDAGGGSGPSAGYTQYTAVAQPSALKACSTGGTCAGVMAFSFSSNVFINSSDEYDGCINLVDRTLASSGSLSCAGSVTGTSVLANASAMVNSTRQVFVGDVVATLLNNTNANTTLAFNSAATIYVTPDSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GT93</accession>
    <name>A0A2S9GT93_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4338</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000032">
        <property type="protein sequence ID" value="PRC90937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90937">
        <property type="protein sequence ID" value="PRC90937"/>
        <property type="gene ID" value="S2091_4338"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC90937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="38" mass="4240" checksum="7D650CA9288F604D" modified="2018-07-18" version="1">MNGKLEGVTRISGADWLLLSIWCGVSHHYDSQLIVLLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTI9</accession>
    <name>A0A2S9GTI9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Collagen triple helix repeat (20 copies)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_4222</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000030">
        <property type="protein sequence ID" value="PRC91034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91034">
        <property type="protein sequence ID" value="PRC91034"/>
        <property type="gene ID" value="S2091_4222"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008160">
        <property type="entry name" value="Collagen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009030">
        <property type="entry name" value="Growth_fac_rcpt_cys_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01391">
        <property type="entry name" value="Collagen"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57184">
        <property type="entry name" value="SSF57184"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0176">Collagen</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015478662" evidence="2">
        <location>
            <begin position="38"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="194"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="194"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="268"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="307"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="488" mass="50478" checksum="97B5D9C2527D6448" modified="2018-07-18" version="1">MNSRCKNGTLYSCGYARRLLHFIFGLALVLLSTPTFSADCAAGEKPTYSTSGSSQSASFQGACDAYSENFLSSVHNYRGEIIVKYYPDQGRCSFTKIAPVYYYTTFIKASCSIKICPPGQALNYQNVCVMPSCPPGQVRDKNFNCIPKPPPPDCPTGTVNGGIDANGDRICSAKICPPPSKLNSDGLCGHDNGLGDKGDKGDKGDKGDKGDKGDKGDKGDKGDKGDKGDKGDKGDKGDKGDKGDKGLQGNQGIQGQQGDKGDKGDKGLQGTQGQQGVKGDTGMQGVTGQAGQNGINGSDGAVGATGATGATGSSGQTGAAGVAGGTGTAGKAGADGKDGKDGEDICKLHPDLTACMNSSVSGTCASTTCDGDAIQCAILKTSQKQYCELTDKKDKAYALGDELMKGDSQTYPSPNNAQVLDLSTGQLDQTGFMGGGAFFSDKYISINGHSIKIPFSDMAQYLIALRYLIMVLAGIQSYKMMSGTILRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTJ2</accession>
    <name>A0A2S9GTJ2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">PilX N-terminal</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_4317</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000031">
        <property type="protein sequence ID" value="PRC91021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91021">
        <property type="protein sequence ID" value="PRC91021"/>
        <property type="gene ID" value="S2091_4317"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025746">
        <property type="entry name" value="PilX_N_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14341">
        <property type="entry name" value="PilX_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="domain" description="PilX_N" evidence="2">
        <location>
            <begin position="14"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14341"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="207" mass="21329" checksum="8511F5418071FDDD" modified="2018-07-18" version="1">MMNIPHHPTQQNQRGVALIASLIIMLLMTIVALSIFRGNNLFEKIAGNTREKQRAFQSAQDALSYAEWWINSTTTPPPVVSSGCPTSAPSAITVCGGNTSYDPGTSASTILGLPLYTGYTPSSMTIKSGGGAQTGGDVNYSKAPGIYIYKEPNPSSNGSTVYEVTAVGYGGANSTVAIVQSYFAFGSAATSGGTPSTTPTATSLSGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTJ6</accession>
    <name>A0A2S9GTJ6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Bacteriophage coat protein B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_4223</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000030">
        <property type="protein sequence ID" value="PRC91035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91035">
        <property type="protein sequence ID" value="PRC91035"/>
        <property type="gene ID" value="S2091_4223"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008020">
        <property type="entry name" value="G8P"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05356">
        <property type="entry name" value="Phage_Coat_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0167">Capsid protein</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0946">Virion</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015692821" evidence="2">
        <location>
            <begin position="31"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="72" mass="7286" checksum="D2CD817B424FDD74" modified="2018-07-18" version="1">MFQIKTLFTKKAVLSTVAASTLVLAQSAHAAIDTGAVVSALTDAAAAVAIVGAIVLTVQVAIKAYKFIARAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTL4</accession>
    <name>A0A2S9GTL4_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">tRNA (guanine-N(7)-)-methyltransferase</fullName>
            <ecNumber evidence="1">2.1.1.33</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">tRNA (guanine(46)-N(7))-methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">tRNA(m7G46)-methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">trmB</name>
        <name evidence="3" type="ORF">S2091_4324</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>guanosine(46) in tRNA + S-adenosyl-L-methionine = N(7)-methylguanosine(46) in tRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42708"/>
            <dbReference type="Rhea" id="RHEA-COMP:10188"/>
            <dbReference type="Rhea" id="RHEA-COMP:10189"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74269"/>
            <dbReference type="ChEBI" id="CHEBI:74480"/>
            <dbReference type="EC" id="2.1.1.33"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">tRNA modification; N(7)-methylguanine-tRNA biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.33" evidence="1"/>
    <dbReference type="EMBL" id="PUGF01000031">
        <property type="protein sequence ID" value="PRC91028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91028">
        <property type="protein sequence ID" value="PRC91028"/>
        <property type="gene ID" value="S2091_4324"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00989"/>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008176">
        <property type="term" value="F:tRNA (guanine-N7-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01057">
        <property type="entry name" value="tRNA_methyltr_TrmB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003358">
        <property type="entry name" value="tRNA_(Gua-N-7)_MeTrfase_Trmb"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23417">
        <property type="entry name" value="PTHR23417"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02390">
        <property type="entry name" value="Methyltransf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00091">
        <property type="entry name" value="TIGR00091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51625">
        <property type="entry name" value="SAM_MT_TRMB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0819">tRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Interaction with RNA" evidence="1">
        <location>
            <begin position="169"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="1">
        <location>
            <begin position="234"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="88"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="113"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="140"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="163"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="167"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="199"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="255" mass="28284" checksum="FC46770E36EA0098" modified="2018-07-18" version="1">MSSKNPHLPESLDSVEPTEEATNLATSKSMFYDPSEHRIRSFVTRAGRVSSGQARALELLGPEFCVPYQKAELDVELTFGRSAPTIFEIGFGMGETSATISGSMPDKNFIGVEVHTPGVGSLLKLIGEQQLSNQRIIQHDAFEVLTHMIKPNSLAGVHVFFPDPWHKARHNKRRLIQPAMVRLITSRLAVGGYLHCATDWEEYADQMLEVLGAESALQNSAEGFAPRPAYRPVTKFENRGLKLGHGVWDLVFVKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTM9</accession>
    <name>A0A2S9GTM9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Peroxiredoxin, OsmC subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4262</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000030">
        <property type="protein sequence ID" value="PRC91074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91074">
        <property type="protein sequence ID" value="PRC91074"/>
        <property type="gene ID" value="S2091_4262"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003718">
        <property type="entry name" value="OsmC/Ohr_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036102">
        <property type="entry name" value="OsmC/Ohrsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019904">
        <property type="entry name" value="Peroxiredoxin_OsmC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02566">
        <property type="entry name" value="OsmC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82784">
        <property type="entry name" value="SSF82784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03562">
        <property type="entry name" value="osmo_induc_OsmC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="144" mass="15327" checksum="14220341EB84BDE5" modified="2018-07-18" version="1">MTEKNASVHWKGQGKTGTGMISTETGALKDYPYGFSSRFEDNRHGTNPEEILGAAHAACFTMAFSFACEKAGVTATSIDTTASVRLSKQGEGFVIDRIALTMQATLSGVDDATFQEIANTAKRDCPLSKALASVPEITLKAVMQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTS9</accession>
    <name>A0A2S9GTS9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HDOD domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4125</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000028">
        <property type="protein sequence ID" value="PRC91124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91124">
        <property type="protein sequence ID" value="PRC91124"/>
        <property type="gene ID" value="S2091_4125"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013976">
        <property type="entry name" value="HDOD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08668">
        <property type="entry name" value="HDOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51833">
        <property type="entry name" value="HDOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HDOD" evidence="1">
        <location>
            <begin position="86"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="339" mass="37340" checksum="D6735793C2CB1228" modified="2018-07-18" version="1">MSTASSRAAAKLAKLAKSLASSKHAAPKNEFLGNYKQLPSYVDARYFDWMAGKSTGNVVEDSSFERKLIEYLAALAASEFAGSNLIPRVPSVMVQLLKRMHEENVSGSELSRIITKDVVLVAAILSEVNSSFYNLSDRINDLSQAILLLGHNRLRMVLAKISFTPIYNAQLGAYTKLTAAKIWEESQKRAFVCYLLAKHQKVDPFMAFLAGLMQDVGLMVALRVFDRSSGSGQLPTSPTFRDEFQQQSMVLSARIGHIWSLPEVVIKAIEGQGMDKTALAKIPLAKVLQKGDFLSKTCVLIDSGQLNVDMERVRGVLTEAEMDCLFTLLEGNKNVSNIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTY4</accession>
    <name>A0A2S9GTY4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_4068</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000027">
        <property type="protein sequence ID" value="PRC91173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91173">
        <property type="protein sequence ID" value="PRC91173"/>
        <property type="gene ID" value="S2091_4068"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015562">
        <property type="term" value="F:efflux transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003423">
        <property type="entry name" value="OMP_efflux"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010131">
        <property type="entry name" value="RND_efflux_OM_lipoprot_NodT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02321">
        <property type="entry name" value="OEP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01845">
        <property type="entry name" value="outer_NodT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0564">Palmitate</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1134">Transmembrane beta strand</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU362097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="515" mass="55488" checksum="1CCDC9F0DE2E6C96" modified="2018-07-18" version="1">MKKMMEFPLKTLALSTSGRAVLGLSLGLALSGCAVGPDFKAPEAPAQTVSSSSDAYSYTSTPVATQTEASEGKSGISQKLVVAQDIPAQWWEVFHSEELDTLIRQALTQSPDLASAQAALRQAKENYNAQSGNTLYPNVSANLGAGRDLASAVSTNVPGGELYNLYNASVNVSYTLDIFGANKRELESMQAAVDYQRFQVEAAYLSLTANLVTTAIKEASLRAQIQATEEILQFQAKQLEVMERQLTLGGIPKVSVLEQRNLLAQTRASLPGLEKSLQQTRNQLAVYAGRLPSDTGLPEFHLDSLQLPQELPVSIPSALVRQRPDIRANEALLHQASAQVGVATANQYPQFTLSASYGSAALTPGNLFKKEWSLWSLGAGITQPIFNGGALSAKRRAALAAYDQIDAQYRSNVLSAFQSVADSLQALDFDAKTLKQQVEVEAIAKQTLDLTTQQFNLGAVNSLALLDAKRTYQTARIGLVQAQAARYADTAALFQSLGGGWWNRPDLKDISVKNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTZ1</accession>
    <name>A0A2S9GTZ1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cation/multidrug efflux pump</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4066</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000027">
        <property type="protein sequence ID" value="PRC91171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91171">
        <property type="protein sequence ID" value="PRC91171"/>
        <property type="gene ID" value="S2091_4066"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2090.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027463">
        <property type="entry name" value="AcrB_DN_DC_subdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001036">
        <property type="entry name" value="Acrflvin-R"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32063">
        <property type="entry name" value="PTHR32063"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00873">
        <property type="entry name" value="ACR_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00702">
        <property type="entry name" value="ACRIFLAVINRP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82714">
        <property type="entry name" value="SSF82714"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="333"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="359"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="385"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="430"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="462"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="520"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="844"/>
            <end position="864"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="871"/>
            <end position="892"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="943"/>
            <end position="967"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="973"/>
            <end position="993"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="1018" mass="109738" checksum="92E5BDD3A685119D" modified="2018-07-18" version="1">MKFTDLFIRRPVLAIVVSLLIVVLGVKSLFSLPVNQYPKTQNAIVTVSTAYYGADAQTVAGFITQPLESAISQAQGIDYLSSSSTNGVSTITATLRLNYDANRALTEISTQVNSVKNQLPAQAQVPVMTVQTGQTTDAMYMGFYSDTLPTNDVTDFLLRAVKPKLDSVDGVQTAEILGARTFALRAWLDSGKMAAFGVTAADVSAALASNNYLTALGATKGQMVTVPLTAGTDLHSVDEFKQLAVKQSNGAIVRLEDVATVTLGSENYDFNVAFSGVRSVFIGIKVAPEANILDVAERVRKAFPALQSELPHGLTGKIVYDSTEFITTSISEVIKTLLEALLIVTIVIYLFLGSFRAVVIPVIAMPLSLIGTFFIMLMLGYSINLLTLLALVLAIGLVVDDAIIVVENVDRHMKEGKSPLESSLLAARELGGPILAMTVVLIAVYVPIGFQGGLTGALFTEFAFTLAGAVAVSGVVALTLSPMMCSRFFKPEQDTGRFVMFIDRIFEKVRHGYMRILHSLLNTWQVLIVMAVILIVCWVMMFKMSKSELAPEEDQGIVLSLVTGPPTATADQMQTYADQIFKAAKDFPEYKQMFQLTGVPTSNQGIGGVLLKDWDQRTRGAKEVQLELQEKWNKIAGVRVVAFQFPALPGSSGLPVQVLITTTEPFENLNEVAQQVIAKAQASGKFYFLDNDLKLDKPQATLVVDRDKIATLGMTQQDVGQALGAALGGGYVNYFSIAGRSYKVIPQVLQVNRLNPDDLLDFHIRTPAGDMIPASTIAHITTTVVPEAINHFQQLNSATISGVAGVSQGEALDILRNALKEVAPTGYTMDYSGQSRLFMNESGGFAATAVFALIIVFLALAAQFESFRDPLVILVSVPLALFGATIFIFWGFTSINIYTQVGLVTLMGLISKHGILIVEFANQLRNKGMSKREAIEEAASERLRPILMTTAAMVFGVLPLVIASGAGAAGRHAMGLIIFTGLSIGTLFTLFVVPAMYMFIAGEHVAVNEVDKKIAEMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GU41</accession>
    <name>A0A2S9GU41_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ABC-type sugar transport system periplasmic component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4119</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000027">
        <property type="protein sequence ID" value="PRC91224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91224">
        <property type="protein sequence ID" value="PRC91224"/>
        <property type="gene ID" value="S2091_4119"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008643">
        <property type="term" value="P:carbohydrate transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025997">
        <property type="entry name" value="SBP_2_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13407">
        <property type="entry name" value="Peripla_BP_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Peripla_BP_4" evidence="1">
        <location>
            <begin position="49"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="329" mass="35753" checksum="FADB0052A1F12CAD" modified="2018-07-18" version="1">MGLVRLWLLFFIVFVLASCGNSSNQTEKSAASTAQMSASVPSAKKPLKIALVLKTQTNPFFVEMEKGARRAEKVLGIELLVRNSSQETFIEEQIQIVEELIEAKVDALVIAPGDSQRLIPSIKKAQSAGIVIINIDNPLDQKMMQNQQMQPIPFISVDNESASYHVSMLVADKIHKPTQVALLEGLPGAGNAVMRTNGALRAIKQNPMMHLVAEETAHWKIDEAHEVARHIFMMHPKVGALICANDMMALGAIQYLADSGRKNVLVVGYDALDEARAAIKAGTMLATVDQQAAEQGYQGVALAVRALKGEKIPPVLIIDTRVITADTLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUC3</accession>
    <name>A0A2S9GUC3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Stress-induced morphogen</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3974</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the BolA/IbaG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000025">
        <property type="protein sequence ID" value="PRC91303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91303">
        <property type="protein sequence ID" value="PRC91303"/>
        <property type="gene ID" value="S2091_3974"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002634">
        <property type="entry name" value="BolA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036065">
        <property type="entry name" value="BolA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01722">
        <property type="entry name" value="BolA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003113">
        <property type="entry name" value="BolA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82657">
        <property type="entry name" value="SSF82657"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="93" mass="9916" checksum="AE6C68AE9C5CFEE3" modified="2018-07-18" version="1">MNNLSASRIAKIEQRLAVLNPISCQIEDDSALHAGHAGAASGAGHFRVTISSEKFNGIKSIQRHRLVYDAVGDLMQTDIHALVITALAPSEVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUG9</accession>
    <name>A0A2S9GUG9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">RNB domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3893</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000024">
        <property type="protein sequence ID" value="PRC91348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91348">
        <property type="protein sequence ID" value="PRC91348"/>
        <property type="gene ID" value="S2091_3893"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004540">
        <property type="term" value="F:ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001900">
        <property type="entry name" value="RNase_II/R"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00773">
        <property type="entry name" value="RNB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00955">
        <property type="entry name" value="RNB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNB" evidence="2">
        <location>
            <begin position="239"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="647"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="648"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="676"/>
            <end position="699"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="699" mass="77253" checksum="F1B65B4734D2DC2B" modified="2018-07-18" version="1">MNVFFEESGDFKAGAVMSQTPDSYQVELASGKRCKVKSRDVLIQFAAPSAEQLLREAHVIAEEIDLDFLWEVAGLEEFGYADLGKEYFGATLSPAQSAGLIFRLHSAPIYFYKKGRGHYKAAPAASVQAALAGIEKKKQQAIIQADYVEQLKAGTLPSSMQAMAQQLLYKPDKNTLEYKALAAACQELHTSPERLMLATGGIASAKDLHFSKFLFDFFPKGTGFSHLMGNVTPPELPKNLPIADVAAFSIDDISTTEIDDALSVKTLADGMLQIGIHIAAPGLGINREDAIDNIARSRMSTVYMPGDKITMLPNELVEIYTLGAGQTRPAVSLYATVNPADWSLISTVSKIEAVPISENLRNNTLDELVTEEALAANEGDYPHKADIAVLWQWAQSLEQGRNLKRAGFGLKPEQNNRTDFNFYVEDDVVSIVARKRGSPLDKIVAELMIFANSTWGKLMNDHGIPGIYRSQGVGNGGWAARMQVKMLTHAAPHHNLGVDQYAWSTSPLRRYTDLVNQWQIMACIQHGVTAPLVAPFKPRDATLFAIVSAFDAMYSGYNDFQSSMERYWCLRWFAQEWQAQRAKHVEALVMKEDLLRLVDIPLVIRLSGLPSMPRGSRVMLDIIGWDEVDLTLEARFLELLSSPDTALTIDEEETEADQEESSDEIGDEIADETATEIENDSLSTPEIPELSTDTHQPEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUH2</accession>
    <name>A0A2S9GUH2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3898</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000024">
        <property type="protein sequence ID" value="PRC91353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91353">
        <property type="protein sequence ID" value="PRC91353"/>
        <property type="gene ID" value="S2091_3898"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="64" mass="7327" checksum="F6B79F57059B4BE9" modified="2018-07-18" version="1">MSRRIGDVLKGSKLGEFWKYRVGDWYLICEIRARRTDDERIASNQSTGLAASEKAGILPYLYDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUM4</accession>
    <name>A0A2S9GUM4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cation/multidrug efflux pump</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3850</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000023">
        <property type="protein sequence ID" value="PRC91435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91435">
        <property type="protein sequence ID" value="PRC91435"/>
        <property type="gene ID" value="S2091_3850"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007156">
        <property type="term" value="P:homophilic cell adhesion via plasma membrane adhesion molecules"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2090.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027463">
        <property type="entry name" value="AcrB_DN_DC_subdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001036">
        <property type="entry name" value="Acrflvin-R"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002126">
        <property type="entry name" value="Cadherin-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32063">
        <property type="entry name" value="PTHR32063"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00873">
        <property type="entry name" value="ACR_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00702">
        <property type="entry name" value="ACRIFLAVINRP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82714">
        <property type="entry name" value="SSF82714"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50268">
        <property type="entry name" value="CADHERIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="337"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="360"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="431"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="463"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="528"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="856"/>
            <end position="873"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="880"/>
            <end position="900"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="906"/>
            <end position="931"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="951"/>
            <end position="972"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="984"/>
            <end position="1010"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="2">
        <location>
            <begin position="651"/>
            <end position="758"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="1025" mass="109771" checksum="83367A8B3155B805" modified="2018-07-18" version="1">MSFSAPFIHRPVATTLMTVAIALAGAIAFNILPVSPLPQVDFPTISISAALPGASADIMASSVATPLERQLGHIAGVTEMTSSSTLGNTSITIQFDLSRDIDGAARDVAGAINAARSYLPTNLPANPTYRKVNPADSPILILGLTSEKYGPDKLYDVASTVIQQKLSQIQGVGQVNLGGGTLPSVRVEANPTQLASYGLTIANLKSMLSLQNADQAKGQISDGAVTADILANDQISKAAQYRPLIVGTKNGAAIRLSDVAEVTDSVQNLHAAGYLNGKRAVMLIIFRQPGANIIDTVDSIRAQLPLIQAAIPFGINTAVVLDRTTTIRASVNGVERTLLISIALVIMVVFLFLRNSRATLIPAVAVPVSLVGTFAVMYLCGYSLDNLSLMALTISTGFVVDDAIVVMENITRHLEAGMSPFEAALKGAAEIGFTVFTISISLIAVFIPLLLMGGIVGRLFREFAITLSTAILVSMIVSLTATPMMCAFLLKNQRNEQHGRFYIASEKIFDSILDKYRRSLHWVLDHPTPTLIVLLSTIALNVLLVIVIPKGFFPQQDTGAIAGGLQGPQDSSFPAMNSAVLQVVDIIKRDRAVLNVIGFTGGSSATNTGFIFIALKPLADRKANAAEIINRLRPKLNRLPVASVFLQASQDLRIGGRSSNAMYQYTLQSDNVQDLFKWGPLLLKQMKLLPGFLDVNSDQQNGGLEQMVNYDRIAAARLGLTVQALDSGLYNAFGQSEVSIIYTQLNQYYVVLEVAPQYSQSPEGLKNIYFNTNTGGNIPLAAIATNQTNTTPLAVNHTGLFPSVTVSFNLAPNVSLSDATRLIEQLHQRLGTPSSIQGFFAGTLQAYQQSLSTEPFLIAAALLAVYIVLGILYESMVHPLTIILSLPPASVGAMLALMLFKEDLGITAIIGIVLLIGIVKKNAIMMIDFALQAQRNEGKSPADAIFEACMLRFRPILMTTMAAILGALPLALGSGMGYELRRPLGITIIGGLLMSQLLTLYTTPVVYLAFDRLRLRILANKKLHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUM6</accession>
    <name>A0A2S9GUM6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">CheB methylesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_3829</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000023">
        <property type="protein sequence ID" value="PRC91414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91414">
        <property type="protein sequence ID" value="PRC91414"/>
        <property type="gene ID" value="S2091_3829"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000156">
        <property type="term" value="F:phosphorelay response regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008984">
        <property type="term" value="F:protein-glutamate methylesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035909">
        <property type="entry name" value="CheB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000673">
        <property type="entry name" value="Sig_transdc_resp-reg_Me-estase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01339">
        <property type="entry name" value="CheB_methylest"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52738">
        <property type="entry name" value="SSF52738"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50122">
        <property type="entry name" value="CHEB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0145">Chemotaxis</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CheB-type methylesterase" evidence="3">
        <location>
            <begin position="1"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="12"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="39"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC91414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="199" mass="21843" checksum="653420118ADDF7C6" modified="2018-07-18" version="1">MKNFPIVCVGGSAGGLNAYIRLLKNLPVNMGVAIVIVNHITIFPTQLHEILPNYTGMPVKLITESLLVEPDHVYIIPENRDLHVQNGEFQLKPISKPRGWPDVITVFLRSLVRYWDGKLIAVIVSGYDGDGAAALCDIQQVGGITIAQKLDTASHPDMPESAIESGCIDFILSPEDIAEKLISIARNQEKNDVEFTDVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUU7</accession>
    <name>A0A2S9GUU7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Flagellar protein YcgR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_3783</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000022">
        <property type="protein sequence ID" value="PRC91505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91505">
        <property type="protein sequence ID" value="PRC91505"/>
        <property type="gene ID" value="S2091_3783"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009288">
        <property type="term" value="C:bacterial-type flagellum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035438">
        <property type="term" value="F:cyclic-di-GMP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009875">
        <property type="entry name" value="PilZ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009926">
        <property type="entry name" value="T3SS_YcgR_PilZN"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07238">
        <property type="entry name" value="PilZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12945">
        <property type="entry name" value="YcgR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0975">Bacterial flagellum</keyword>
    <keyword evidence="1" id="KW-0973">c-di-GMP</keyword>
    <keyword evidence="6" id="KW-0966">Cell projection</keyword>
    <keyword evidence="6" id="KW-0969">Cilium</keyword>
    <keyword evidence="6" id="KW-0282">Flagellum</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="T3SS_YcgR_PilZN" evidence="5">
        <location>
            <begin position="98"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="domain" description="PilZ" evidence="4">
        <location>
            <begin position="189"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF12945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC91505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="300" mass="32869" checksum="C46AF4D48F8C7EEE" modified="2018-07-18" version="1">MADLTSLIPLSKSDFAVGKVTQRSIYDRHGKLLLASGVVIESQNQLNGLVNQGYVQKNSWDTPAKPKPSISAPAKVIEEPVAPPKEVFSQMDDVRWYVGETLHMQALNDTDSRFVVKLIGYIKGKSVLVTAPVIDGKYILIRDNQTFVVRAFQGKKAFAFTVTALKSVYTPHPYLHLSYPKQVNSSVIRHDARAAVKIIASVSFLNPVRTAAATLLDLSMGGTSGIIKQAIAEKKETGTITFKINVVGNEGLLSLDFIVRSIAPTEEGDGYRYGFEFLNVPAQHKLILSAFVHQTIAELV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUU8</accession>
    <name>A0A2S9GUU8_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Flagellar hook-associated protein 2</fullName>
            <shortName evidence="5">HAP2</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Flagellar cap protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_3767</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2 5">Homopentamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Secreted</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Bacterial flagellum</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the FliD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000022">
        <property type="protein sequence ID" value="PRC91489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91489">
        <property type="protein sequence ID" value="PRC91489"/>
        <property type="gene ID" value="S2091_3767"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009421">
        <property type="term" value="C:bacterial-type flagellum filament cap"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009424">
        <property type="term" value="C:bacterial-type flagellum hook"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007155">
        <property type="term" value="P:cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040026">
        <property type="entry name" value="FliD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010809">
        <property type="entry name" value="FliD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003481">
        <property type="entry name" value="FliD_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30288">
        <property type="entry name" value="PTHR30288"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07195">
        <property type="entry name" value="FliD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02465">
        <property type="entry name" value="FliD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0975">Bacterial flagellum</keyword>
    <keyword evidence="8" id="KW-0966">Cell projection</keyword>
    <keyword evidence="8" id="KW-0969">Cilium</keyword>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-0282">Flagellum</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <feature type="domain" description="FliD_N" evidence="6">
        <location>
            <begin position="25"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="FliD_C" evidence="7">
        <location>
            <begin position="255"/>
            <end position="434"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC91489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="683" mass="67514" checksum="8F60591D93AE5E31" modified="2018-07-18" version="1">MSVNDVANSSASTGLGIISSLGIGSGLNASSIISQLMAVQDEPVNLLQNQEAGDQTTVSAFGSLQSALSQFQTSLQSLNNISQYQSQSATIANSAVATVSATSAAAVGTYSLQVNQLAQSQTLIAAGQASTTSAIGVGTISFNLGTTNGTVTNGQYGAGTTFTNSGAAAKTVTITSADDSLTGIAAAINAANIGVTASILNDGSSTPNRLSLTSTATGAANSLQISVSGDPALSSLLDQDPTSTTGQNLTQTSAAQNAQFTLNGLAISSSTNTDSTVIPGVTLNLLSTNLTSPTTLSISQTNTGTVNAINSFVKAYNTIESTISQATAYDSSTKQSGPLQGQNSVVSILSQMQGVLDNPVPGASSTLSMLAQVGVSFNSDGTLSVNSTTLQTALASNPTAVAGLFASTGSSTDSLINYTGTTSATQPGAYAVNISQLATQANTAGSAAANLTITSGVNDTLQVDLNGVTSNVTLAAGTYTSASLADALQTAINTNNSFTVAGGTATVTQNGGVLTITSNLYGSKSAASITGGDGESDLLGGAPITTAGVDVAGTINGVSATGSGQTLTSILGNSTGLSVLVNGGGLGSRGTINYTQGYINELNNLMTSVLGKNGQIASATAGLNATITGIQSSVASDNNLNQQILTNLQAEYSALDVTISKLTSTQTFLTQQLASLSSSSSSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GV32</accession>
    <name>A0A2S9GV32_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3695</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000021">
        <property type="protein sequence ID" value="PRC91579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91579">
        <property type="protein sequence ID" value="PRC91579"/>
        <property type="gene ID" value="S2091_3695"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="30"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="56"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="87"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="110"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="172"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="203"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="229"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="252" mass="27096" checksum="2D7B69F9271FDB8B" modified="2018-07-18" version="1">MLITLLLKLLLVPTLIGLVTLSGRRWGPKIAGWLSAFPIVAGPILFFIALDQGNQFAIIAATSTLSAVLAIIVFGLAYVWAAVRLNWIGSLAVALFFYTLAVLGLKLLSLSLYAAAIASVLAIIAAPRLYPKVISRPSNSAPSRFDLPLRMSAGAVLAVSVTYFAPNLGPRLTGIFAMFPVMSLVLTVFSHRSEGREFATNQLRGMLFGWYAFATFCFTLALLLPTMEIAVAFLIATTAALIVQLGSRRFVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVK5</accession>
    <name>A0A2S9GVK5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">BON domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3495</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000019">
        <property type="protein sequence ID" value="PRC91740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91740">
        <property type="protein sequence ID" value="PRC91740"/>
        <property type="gene ID" value="S2091_3495"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007055">
        <property type="entry name" value="BON_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014004">
        <property type="entry name" value="Transpt-assoc_nodulatn_dom_bac"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04972">
        <property type="entry name" value="BON"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00749">
        <property type="entry name" value="BON"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50914">
        <property type="entry name" value="BON"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BON" evidence="1">
        <location>
            <begin position="3"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="domain" description="BON" evidence="1">
        <location>
            <begin position="78"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="domain" description="BON" evidence="1">
        <location>
            <begin position="149"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="218" mass="24316" checksum="9B51FA2FB51BDD34" modified="2018-07-18" version="1">MKTDAQIQQDVIEELKWEQSVNATQIGVEVQDGIVTLTGHVHSFADKWHAERAAQRVFGVKALAIEIDISLPGSSHRNDADIARSVENVLEWNTFLPKDHVKVMVEDGWITLTGEVDWRYQKQALATGIRYLLGVKGVSDHIHIRPVVSSNIVKSNIEAALKRHARDNSNNVSVNVHDNNVTLSGTVDNWSERKLACHAAWGTPGVHKVVDNINIAWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVU8</accession>
    <name>A0A2S9GVU8_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Flagella basal body P-ring formation protein FlgA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_3387</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 4">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the FlgA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000018">
        <property type="protein sequence ID" value="PRC91831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91831">
        <property type="protein sequence ID" value="PRC91831"/>
        <property type="gene ID" value="S2091_3387"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044780">
        <property type="term" value="P:bacterial-type flagellum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017585">
        <property type="entry name" value="Flag_basal_body_FlgA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039246">
        <property type="entry name" value="Flagellar_FlgA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041231">
        <property type="entry name" value="FlgA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013974">
        <property type="entry name" value="SAF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36307">
        <property type="entry name" value="PTHR36307"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13144">
        <property type="entry name" value="ChapFlgA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17656">
        <property type="entry name" value="ChapFlgA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00858">
        <property type="entry name" value="SAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03170">
        <property type="entry name" value="flgA_cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1005">Bacterial flagellum biogenesis</keyword>
    <keyword evidence="6" id="KW-0966">Cell projection</keyword>
    <keyword evidence="6" id="KW-0969">Cilium</keyword>
    <keyword evidence="6" id="KW-0282">Flagellum</keyword>
    <keyword evidence="3 4" id="KW-0574">Periplasm</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="domain" description="SAF" evidence="5">
        <location>
            <begin position="124"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU362063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC91831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="248" mass="25855" checksum="C3B39973B329B80B" modified="2018-07-18" version="1">MKPAVITMLGSIHLLLQVGLGLTTLACVPLHAAEDKQNLQEIRETVKQYLNKESAGISSTSTGTNTVTTEVGAIDSRLNLAPCAALEAFMPGGSHLWGKTTVGVRCLAPQLWVIYVPGVVKIWGNYYVAAKSIAQGQTITEADISTVKGDLTTLASGIVTEPSQALGHTSTMSLAAGIPLRQDGLHLQQVVLQGQTIRLISSGAGFNVSTEAQALNSASEGQLVKVKINSGQVLSGIAKSGGIVEVRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GW07</accession>
    <name>A0A2S9GW07_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphate-selective porin O and P</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3434</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000018">
        <property type="protein sequence ID" value="PRC91878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91878">
        <property type="protein sequence ID" value="PRC91878"/>
        <property type="gene ID" value="S2091_3434"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023614">
        <property type="entry name" value="Porin_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015418984" evidence="1">
        <location>
            <begin position="30"/>
            <end position="409"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="409" mass="45133" checksum="5CD61F6C906C2E56" modified="2018-07-18" version="1">MMNKKIISIKLTNLIVASLISIFPLLSYAGDAPTPTGTDNVATETPMDPKSPVIPDTGSNFHVTGFLSVIGGNIFNGSYPPNYIASGGPTQLIGVNCPCYYADYSNGGVYGPNFSLKPESHAGVQIKYDFSPQFNFVGQVTVRGTDNDPNIQWAYVDYKLNDHWEIHVGRQRIPLYYYSPFQDVGFAIPWVAVPPELYGWEATNYDGASLRYSNSFGNTNFTSSIYSGGEKLGYSAFYTNPGDTDVHWNNIVGADAEINNGPLTLRLVYLQANTLAINIPQGLDSASKIEAYGLAVNLDFDTWFMLSEVTQLTRDYGSVQAKQTDPASTIGVGYRLGKWTPFVNYALFTQHSSPYTPSDEFAYKRASLTLRYDIDSSSDIKTQVDRNWDTTNTSGGNVNVVRVSYDRVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWF2</accession>
    <name>A0A2S9GWF2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="8">MMPL family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_3328</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000017">
        <property type="protein sequence ID" value="PRC91986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91986">
        <property type="protein sequence ID" value="PRC91986"/>
        <property type="gene ID" value="S2091_3328"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004869">
        <property type="entry name" value="MMPL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000731">
        <property type="entry name" value="SSD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03176">
        <property type="entry name" value="MMPL"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50156">
        <property type="entry name" value="SSD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="226"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="254"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="283"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="327"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="368"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="414"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="617"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="640"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="664"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="710"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="745"/>
            <end position="772"/>
        </location>
    </feature>
    <feature type="domain" description="SSD" evidence="7">
        <location>
            <begin position="263"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="domain" description="SSD" evidence="7">
        <location>
            <begin position="652"/>
            <end position="767"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC91986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="786" mass="85911" checksum="2FAA58C6E01ED261" modified="2018-07-18" version="1">MLTSLIHKLEHWLFSHRAVVLGSLAILTAVMAYFALQLRMDAGYEKQIPIGHEYVQTFQQYRADLFGANRLTVVVKAKHGKIWTKEGLAILYKVTQATTYLPNIDRLGVQSLWTPNSYVNEITEEGFRSQPVIPGTVTPDSLTAEDIAHIQSAASEGGFIGSLVSRDESAAMITAEIGETDNEGKKIDYIKYNHLIEEKLRAPFENADYEVQIIGFAKQIGDIADGAQAVLVFCAIALLLTGLAVYWYSHSIRFTLLPIACSLTSLVWQFGTLRLLGYGLDPLGVLVPFLVFAIGVSHGVQQINFITRELAEGKSSFDAARHSFTGLLIPGTLALVTAFVSFVTLLLIPIPMIRELAITASLGVAYKIITNLVMLPVAASCINFPHSYAQKAMKKREQRARWLLPLTKVAKPRNALMVLLVTFGLLGVSIWQSHDRVVGTLQPGAPELRPEARFNRDAVAISSSFDVGLDWLSVVIQSPPESCESPAVGTYGDKLEYALKGVPGIVSISSFPGNLRTYNEGYNEGNPKMNAVPIDSGNYAGLSTEIGRVRGYLNKDCSMTAVHLYLADHKATTINRVIAEVKAFRAAHVEPGITIRLAAGNAGVLAAINDEVEKSELPMMLYVYATIALLVFIVYRDLRAVIACCLPLTVGTFIGYWFMKAFDIGLTVATLPVMVLAVGIGVDYAFYIYNRLQAHLAAGETIAKAIEHSITEVGMATIFTAITLAIGVATWSFSELKFQADMGKLLAFMFIVNLVMAMTALPAIAVFLEWAFPRKSKVRVSAVFSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWJ8</accession>
    <name>A0A2S9GWJ8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PD-(D/E)XK nuclease superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3234</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000016">
        <property type="protein sequence ID" value="PRC92099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92099">
        <property type="protein sequence ID" value="PRC92099"/>
        <property type="gene ID" value="S2091_3234"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.320.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011604">
        <property type="entry name" value="PDDEXK-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038726">
        <property type="entry name" value="PDDEXK_AddAB-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12705">
        <property type="entry name" value="PDDEXK_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PDDEXK_1" evidence="1">
        <location>
            <begin position="671"/>
            <end position="926"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="930" mass="103488" checksum="368D5563AD6337AB" modified="2018-07-18" version="1">MANPFLLQLSTMPLSSLLLPPSRQFWPDCAQQVIAAMQPDGNFADASRSSELDFSALRVIVPAYEHASLLIRAMAQQLNGNFIPPRINTLSAWLALQIPAADAKAAVSESERLMALYAQLREHGWLKKLFSARKNTDLLPLAQTLLTLSDELTQAMLPLVVNETGLNKNLAQAEQVWHQALASLPMPVQQVLSDEAQLVWQIWTSQLDGQDAISLRFQKMLRLAEHAPDPLLWLNPVVPDGLEQQFLTAYAKKQAVQVISLDWRATKLANVFSTAWQEVVEKEDEPPAADALVISAPLNNIRTLAADSLEQEAQLGAQTILDWLQQGKTSIALIAQDRVVARRIRALLERAQVHVSDETGWKLSTTRAAAALAAWFDVVVTRADTVMLLDLLKSPYFEPESMAAFDEKTSWVMAIEMALLRANVVGGWDSIIYALGKTPECAGLLDNLKSTAGNYTQHKSLTEWLTLTQQTLREFGISASWQQDAAGQQVAQLLEKLREDCSQLSDTFSFAEWRVFINLQLESTALQGAKHDQRVLMLPLNGARLRSFDAVLMAGCDAAHLPSQPKEVLFFTNAVRRECGLITHEQRQRQQLRDFAELLSANSDVVLSWQSQQRGEENPVSPWLERLNLCLQRAGLTRLETQQVQLSTQSLPTIIPQQPKPAAASLQPANLSASGYNSFLACPYQFFATRMLGLSSIDTLSDMPEKRDYGGWLHAILKTYHDSLKAQPELYPAAKQEALLREISQTMFTNVLQKSPAALGYSIRWEKVIPAYVAWSQRYAESGWQFEIGEVWLERSLEWADGQITLRGQIDRMDVNQQGEHAVLDYKTTPIGALNKKLKQAEDQQLPFYGLLAATDEVTISSAHYVALEMTGEKLADASAANYAVWQQELQQAIIQNVTAIGQGAALPAQGISQVCQYCEVRGLCRKGAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWK9</accession>
    <name>A0A2S9GWK9_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Oligopeptidase A</fullName>
            <ecNumber evidence="8">3.4.24.70</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">S2091_3252</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>Hydrolysis of oligopeptides, with broad specificity. Gly or Ala commonly occur as P1 or P1' residues, but more distant residues are also important, as is shown by the fact that Z-Gly-Pro-Gly-|-Gly-Pro-Ala is cleaved, but not Z-(Gly)(5).</text>
            <dbReference type="EC" id="3.4.24.70"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="9">Binds 1 zinc ion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the peptidase M3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.70" evidence="8"/>
    <dbReference type="EMBL" id="PUGF01000016">
        <property type="protein sequence ID" value="PRC92117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92117">
        <property type="protein sequence ID" value="PRC92117"/>
        <property type="gene ID" value="S2091_3252"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06456">
        <property type="entry name" value="M3A_DCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1370.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034005">
        <property type="entry name" value="M3A_DCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024077">
        <property type="entry name" value="Neurolysin/TOP_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045666">
        <property type="entry name" value="OpdA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045090">
        <property type="entry name" value="Pept_M3A_M3B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001567">
        <property type="entry name" value="Pept_M3A_M3B_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11804">
        <property type="entry name" value="PTHR11804"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01432">
        <property type="entry name" value="Peptidase_M3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19310">
        <property type="entry name" value="TOP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 9" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2 9" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="TOP_N" evidence="11">
        <location>
            <begin position="30"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M3" evidence="10">
        <location>
            <begin position="226"/>
            <end position="676"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00026100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF19310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PRC92117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="679" mass="76072" checksum="A7BA1D3AE1BE0570" modified="2018-07-18" version="1">MTNPNTNPLVDFTDLPRFDAITADDVAPAITALLEQCKAVVTQIENDPVSATWENVVEPLENATEKLSRAWGIISHLHGVCDTPELRAAYNENQPLITEFFTALGQNLVLFKKYQALHDGPEFTAYSVPRKKIIQNAIRDFKLSGAELAADKKLRYAEIQEQVAALSTKFSENILDATNHYSLHIDNAEALAGLPEDALLAARTKAEQAEQSGYLFGLQFPSFYPVLQYANDRALRATIYRANTTKASDLGENPEWDNTELMQQILALRNEEAHLLGYANFAQVSLVAKMAESTEQVSQFLLDLAARAQPFAVKDLEELRHFAKETLGLDDLQAHDIAYASEKLREQRYAFSEQEVKQYFPEPQVIQGLFSITNTLYGVDIKPDQASTWHPDVKFFRIEKNGQLIGQFYLDLYARDGKQGGAWMDDARGRRSTADGIQTPVAYLTCNFTAPAANAPAYFTHDEVITLFHEFGHGLHHMLTQVDELGVSGLSGVEWDAVELPSQFMENFCWEWEVLQQMSAHSDTGQPLPRALYDKMLAAKNFQSGLQTLRQVELSLFDMRLHDGYLEQHQLSVQALLNQIRAQISVMKTPEFNRFQHAFSHIFAGGYAAGYFSYKWAEVLSADAYAAFEEAGNNAEIGIKFQKEILAVGGSRTALESFIAFRGRAPEIDALLRHSGMKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWT0</accession>
    <name>A0A2S9GWT0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">PAS domain S-box protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_3086</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92170">
        <property type="protein sequence ID" value="PRC92170"/>
        <property type="gene ID" value="S2091_3086"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="3">
        <location>
            <begin position="11"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="4">
        <location>
            <begin position="230"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC92170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="281" mass="31937" checksum="B9F1124F6CF1638A" modified="2018-07-18" version="1">MPKLSDFLNASILIVDDQEANVLLLENMLKNVGYTQVTSTTDPRQVCALHAEHRYDLILLDLQMPTMDGFEVMQGLSEIEADGYFPVLVITAQPAHKLRALQAGAKDFVSKPFDLLEVQTRIHNMLEVRLLYRKLANYNKELEAEVQARTAELRESEARFKSFTELSSDWYWEQDQAGKFTKVYGPVFEMLGIDAQEMLGSADSTSTNFTGQWNASERAQLDANIAARRPFLDFIYTRYQPDGKTQYLQVSGEPIFDSNSCFVGYRGIGMDVTERMQAKND</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWV6</accession>
    <name>A0A2S9GWV6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3116</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92200">
        <property type="protein sequence ID" value="PRC92200"/>
        <property type="gene ID" value="S2091_3116"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10600">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021866">
        <property type="entry name" value="SpoIIAA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038396">
        <property type="entry name" value="SpoIIAA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11964">
        <property type="entry name" value="SpoIIAA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SSF52091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="136" mass="14953" checksum="12F05252CCACC023" modified="2018-07-18" version="1">MLDYSISQPEGILELAPHTSLSKEDFDGLNTAINAYLADHTKLQGILIHSMEFPGWEDFGGLAAHMHFVGHHDKSVERVAIVTDSHFAGIAASLGNYLTSAEIRHFPFIDDAKARHWLETAPVQLSTSAKNLQLTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWW1</accession>
    <name>A0A2S9GWW1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">MatE: MATE efflux family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3118</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92202">
        <property type="protein sequence ID" value="PRC92202"/>
        <property type="gene ID" value="S2091_3118"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042910">
        <property type="term" value="F:xenobiotic transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002528">
        <property type="entry name" value="MATE_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01554">
        <property type="entry name" value="MatE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006603">
        <property type="entry name" value="DinF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00797">
        <property type="entry name" value="matE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="90"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="127"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="157"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="192"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="238"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="273"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="315"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="346"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="385"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="417"/>
            <end position="437"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="457" mass="49723" checksum="D53EE060EBBC6E1C" modified="2018-07-18" version="1">MRLKDTRATWHLAWPIAVGQLASTGTAFIDTVMAGHVSAGDLAAVSVGSSIWVTLIVTMLGYLLATSPLVAQKVGANDTGSISALTQQALVQALIIAALAWIATRLLLPIFPHLGLEPLIANKAADFLKAISWGLPAFALYRVLYSYSAALKHTKPMMIISVFCLLLNIPANWILIYGHLGFPAMGGVGCGWATAFCVWVNFILLSAWILRTDYYQQTHPFRAWQGWNSAVQKQLFKLGLPIGIMFLVEVSAFSFIALIIAKLGTTSVAAHQIALNFCSLTFMVPMAVGTALTVRVGHAVGAKNFEEARAIGQNGIRLGLFIAVMSGCLMIFGSHWVSRWYTQDEAVLALAGNLIVLAGIFQFSDITQVVSAGVLRGYKVTRVPMMIHMTAFWIIGMPLGYLLTFGTDTYPGLGVRGYWIALIIALTFTALALQFLFRRTSHSQLILHNNQHNLLNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWW7</accession>
    <name>A0A2S9GWW7_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">3-oxoacyl-[acyl-carrier-protein] reductase</fullName>
            <ecNumber evidence="3">1.1.1.100</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_3130</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>a (3R)-hydroxyacyl-[ACP] + NADP(+) = a 3-oxoacyl-[ACP] + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:17397"/>
            <dbReference type="Rhea" id="RHEA-COMP:9916"/>
            <dbReference type="Rhea" id="RHEA-COMP:9945"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:78776"/>
            <dbReference type="ChEBI" id="CHEBI:78827"/>
            <dbReference type="EC" id="1.1.1.100"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.100" evidence="3"/>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92214">
        <property type="protein sequence ID" value="PRC92214"/>
        <property type="gene ID" value="S2091_3130"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00094"/>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004316">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011284">
        <property type="entry name" value="3oxo_ACP_reduc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01830">
        <property type="entry name" value="3oxo_ACP_reduc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="3" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="3" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="3" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="2 3" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="157"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="16"/>
            <end position="19"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="41"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="65"/>
            <end position="66"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="92"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="157"/>
            <end position="161"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="190"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR611284-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR611284-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU366074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC92214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="250" mass="25937" checksum="C6263899DAF88FF5" modified="2018-07-18" version="1">MKPIFDLTGQVALVTGASRGIGRAIATLLAERGATVIGTATTEAGAANISAYLAEAGKGCGVVLNVCDPVASVALVEQIQKENNGLSILVNNAGITQDQLAMRMKDEEWDDVITTNLTAVARLSRAVLRTMMKAKYGRIINITSVVASAGNPGQINYAAAKAGVAGMSRALAREIGSRNITVNCIAPGFIDTDMTKALNEQQSATILQQIPLGRLGQPQEIAAAALFLASSEAAYVTGTTMHVNGGMYLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWY2</accession>
    <name>A0A2S9GWY2_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 12">GTP 3',8-cyclase</fullName>
            <ecNumber evidence="3 12">4.1.99.22</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Molybdenum cofactor biosynthesis protein A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">moaA</name>
        <name evidence="14" type="ORF">S2091_3145</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>AH2 + GTP + S-adenosyl-L-methionine = (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate + 5'-deoxyadenosine + A + H(+) + L-methionine</text>
            <dbReference type="Rhea" id="RHEA:49576"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:131766"/>
            <dbReference type="EC" id="4.1.99.22"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="12">Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 12">Cofactor biosynthesis; molybdopterin biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12">Monomer and homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the radical SAM superfamily. MoaA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.99.22" evidence="3 12"/>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92229">
        <property type="protein sequence ID" value="PRC92229"/>
        <property type="gene ID" value="S2091_3145"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00344"/>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019008">
        <property type="term" value="C:molybdopterin synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061798">
        <property type="term" value="F:GTP 3',8'-cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904047">
        <property type="term" value="F:S-adenosyl-L-methionine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006777">
        <property type="term" value="P:Mo-molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01225_B">
        <property type="entry name" value="MoaA_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013483">
        <property type="entry name" value="MoaA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000385">
        <property type="entry name" value="MoaA_NifB_PqqE_Fe-S-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010505">
        <property type="entry name" value="Mob_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06463">
        <property type="entry name" value="Mob_synth_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02666">
        <property type="entry name" value="moaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01305">
        <property type="entry name" value="MOAA_NIFB_PQQE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="9 12" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="7 12" id="KW-0408">Iron</keyword>
    <keyword evidence="8 12" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="11 12" id="KW-0456">Lyase</keyword>
    <keyword evidence="5 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 12" id="KW-0501">Molybdenum cofactor biosynthesis</keyword>
    <keyword evidence="6 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="13">
        <location>
            <begin position="34"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="43"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="50"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="54"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="56"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="57"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="97"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="101"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="132"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="156"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="194"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="228"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="295"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-substrate</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="298"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-substrate</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="300"/>
            <end position="302"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="312"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-substrate</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="PRC92229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="373" mass="41370" checksum="F2872015DA2F578C" modified="2018-07-18" version="1">MSDRIIPIIAQLNNNLQPPYSGAHTVANGLLLDTLQRPLRDLRISVTDRCNFRCVYCMPREVFDQNYPYLPHSALLTFEEITRLANLLVAHGVTKIRLTGGEPLLRKNLEKLVAMLRRIETPSGVPLDLTLTTNGALLAKKAQLLKDAGLDRVTVSLDALDDTIFKRMNDADFSVTEVLHGLDVAQQVGLGPIKINMVVKAGVNEGQILPMARHFKGSPFILRFIEYMDVGSSNGWKMGEVIASQTVINQISNAAPDMQLIPLQSNYSGETAQRWTYADGSGEIGVISSVTQAFCHDCTRLRLSTEGKLYTCLFASHGHDVRNLLRDNSDDAHISNALAHVWHMRGDRYSELRSQQTSPEIKVSKVEMSYIGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GX27</accession>
    <name>A0A2S9GX27_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putative ATPase related to phosphate starvation-inducible protein PhoH</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_2929</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PhoH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92270">
        <property type="protein sequence ID" value="PRC92270"/>
        <property type="gene ID" value="S2091_2929"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003714">
        <property type="entry name" value="PhoH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002716">
        <property type="entry name" value="PIN_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02562">
        <property type="entry name" value="PhoH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13638">
        <property type="entry name" value="PIN_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00670">
        <property type="entry name" value="PINc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="SSF88723"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PINc" evidence="5">
        <location>
            <begin position="126"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC92270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="590" mass="64524" checksum="4C106E3A27CBA87F" modified="2018-07-18" version="1">MPLPKMPTKPAVILSKEDYPKASAKSAAKSATTPAVNQVAQVANSAANLVNKSRSKPAVLIKPVAKLMTAHTAPQVVAKSPAPTAKTPSIVKPAVLEVKSTTTAKATGTRAKSGTSRSADTAGKTKLFVLDTNVLMHDPSCLFRFEEHDIYLPMITLEELDNHKKGMSEVARNARQVTRSLDALVGDTEHEDISEGIPLSKLGNKEAKGHLLFQTKLQHVNLPQGLPVGKADNQILAVVRALEIEYPNRPIVLVSKDINMRIKARALGLPAEDYFNDHVMEDSDLLYTGLVQLPMDFWNKHGKGMESWQESRNGVSNTFYRVTGPFIATLLVNQFVYLEPNNGEASFYGQVRQINGKTAVLQTLRDFGHAKHSVWGVTSRNREQNFALNLLMDPECDFVTLLGQAGTGKTLLALAAGLAQVLETKTYNEIIVTRVTVPVGEDIGFLPGTEEEKMSPWMGAFDDNLEVLNKSDNDGGDWGRAATQDLIRSKIKIKSLNFMRGRTFVNKFLIIDEAQNLTPKQVKTLVTRAGPGTKIICLGNIAQIDTPYLTEGSSGLTYVVDRFKGWAHSGHITLARGERSRLADHASEVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GX98</accession>
    <name>A0A2S9GX98_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">40-residue YVTN family beta-propeller repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3003</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92344">
        <property type="protein sequence ID" value="PRC92344"/>
        <property type="gene ID" value="S2091_3003"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011045">
        <property type="entry name" value="N2O_reductase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011964">
        <property type="entry name" value="YVTN_b-propeller_repeat"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50974">
        <property type="entry name" value="SSF50974"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02276">
        <property type="entry name" value="beta_rpt_yvtn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015723262" evidence="1">
        <location>
            <begin position="20"/>
            <end position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="419" mass="45444" checksum="6259B38FC77F6A32" modified="2018-07-18" version="1">MKKISLFGLTLFATAAIFAAPEASTPNVATAPAIKSIVTVPGMPPVINPQNIYSENGANMFNPVVKDDLPRIYVPNLRSNDVTVIDPASLKVVDRFKVGYSPQHIVPSWDLRTLWVANNAEGRKDGSLTPIDPRTGKPGKALPVDDPYNLYFSPDGKSAIVVAEAMHRLDFRDPQTMKLQYAIDVPQCKGINHADFSIDGKYALFTCEFEGSIAKIDLVNRSVVGYLKLTMPSTRFKAVPTSTGPINPADTEICSSKKGMPQDIRSSPDGKRFYVADMEADGVHIIDGDAFTKIGFIATGVAAHGIYPSRDGKQFYVSNRGSHQIHGKPRGKGSVTVIDFASEKIVAQWPIPGGGSPDMGNVSANGKELWLSGRFDDEVYRFDTSNGQVTKIAVGKEPHGLTVWPQPGRYSLGHTGNLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXF5</accession>
    <name>A0A2S9GXF5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2763</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92388">
        <property type="protein sequence ID" value="PRC92388"/>
        <property type="gene ID" value="S2091_2763"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="74" mass="7743" checksum="693BB2687F81430B" modified="2018-07-18" version="1">MENQNPINKALEIVSLIFGIGILLVGVLVTGFGIAGLIEGMHGGILAACSMIIFGALIAFVGWLCSKFGFDECQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXV6</accession>
    <name>A0A2S9GXV6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2607</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92552">
        <property type="protein sequence ID" value="PRC92552"/>
        <property type="gene ID" value="S2091_2607"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041492">
        <property type="entry name" value="HAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13419">
        <property type="entry name" value="HAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01509">
        <property type="entry name" value="HAD-SF-IA-v3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="213" mass="24688" checksum="025C88DD18D49994" modified="2018-07-18" version="1">MVEGILWDNDGVLVDTEKLFFQANKDLFAQVDIALTEQHFFDWFLLENRGAWHLLTDHTPDQIKQLRTRRDQIYMQHLHNNERLEISGINELLLGLAPRVPMGIVTSARSDHFELIHSRLDLIRHFRFVVTEEMYSESKPSPEPYLLGLTKLDLPAEKCLVIEDSPRGLHAARAAGIKCIVLRNKMMLDYPFEGAYRVVESVEELSHEINQLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GY08</accession>
    <name>A0A2S9GY08_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Peptidase family M48</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">S2091_2657</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="7 8">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="7 8">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the peptidase M48 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92602">
        <property type="protein sequence ID" value="PRC92602"/>
        <property type="gene ID" value="S2091_2657"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071586">
        <property type="term" value="P:CAAX-box protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07343">
        <property type="entry name" value="M48A_Zmpste24p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027057">
        <property type="entry name" value="CAXX_Prtase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001915">
        <property type="entry name" value="Peptidase_M48"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032456">
        <property type="entry name" value="Peptidase_M48_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01435">
        <property type="entry name" value="Peptidase_M48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16491">
        <property type="entry name" value="Peptidase_M48_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 8" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1 8" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 7 8" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015424247" evidence="10">
        <location>
            <begin position="31"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="79"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="119"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="166"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="194"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="306"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="348"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M48_N" evidence="12">
        <location>
            <begin position="62"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M48" evidence="11">
        <location>
            <begin position="227"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="297"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="6">
        <location>
            <position position="380"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="296"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="300"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="376"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR627057-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR627057-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF16491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PRC92602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="440" mass="48902" checksum="713A158BCF211E69" modified="2018-07-18" version="1">MSKKIFWPTILFVIAISAAIGLLAPTSHNAAARAIGEIAPVSDVWRAALPHDPAAATDAYMARISPAAKARSDAYFEGGYWLTLWDLVMTLVASWLLLTSGVLARLRDKLEQRSRSKGLLVLVMGLGYILLSTLISLPLTVYQGFYREHEYGLANQTLLPWLGEQAIATAVACIIGPLFLALIYWVIRRAPKTWPVWGAVVTVGFMSFMMLLGPVYIDPLFNTYKPITDEKIKQPILSMARANGVPTDNVYEFDASKQSNRISANVSGIFGSAAVRMNDNLLKRTTLPEIKGVLGHEIGHYVLDHIYTGIIEFGIILVVGFAFLHWALRYSITRWGQQFGIRDASDPLGLPLVVGIFSIYMFAATPVLNTMTRVQEAQADAFGLNASQEPDGFAEVDLKLTEYRKSNPGDLEEFFFFDHPSPKKRIFASMRWKAEHLKLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYB8</accession>
    <name>A0A2S9GYB8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Oxidoreductase molybdopterin binding domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2444</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92714">
        <property type="protein sequence ID" value="PRC92714"/>
        <property type="gene ID" value="S2091_2444"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000572">
        <property type="entry name" value="OxRdtase_Mopterin-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036374">
        <property type="entry name" value="OxRdtase_Mopterin-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00174">
        <property type="entry name" value="Oxidored_molyb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56524">
        <property type="entry name" value="SSF56524"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Oxidored_molyb" evidence="1">
        <location>
            <begin position="96"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="196" mass="21801" checksum="C03AF6D9B6CF4693" modified="2018-07-18" version="1">MEKRQFLSSGLVLGTLLIPTLKEASATIQNASAQIILTITGDIKHVNRDKSDVVKDQLMHKQGVHFERAYTFALSDLENLRAKTISPTLEYDARIHQLSGPRLMDVLELVGVNKTKHSSIIFHGIDGYSPEISLALAEKYDYILATKLDGQLLSVGGFGPLFAIYDADRLTEIAQKPLNQRFDKCPWGLYCIEVVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYG4</accession>
    <name>A0A2S9GYG4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2478</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92748">
        <property type="protein sequence ID" value="PRC92748"/>
        <property type="gene ID" value="S2091_2478"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022742">
        <property type="entry name" value="Hydrolase_4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12146">
        <property type="entry name" value="Hydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hydrolase_4" evidence="1">
        <location>
            <begin position="45"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="231" mass="25754" checksum="41D3834128DD897F" modified="2018-07-18" version="1">MLTLVLLPGMDGTGELFDPLLKELREQVDVQVIRYPATLAGYAKLTDFVRMDLPFENDYVLLGESFAGPISVRLAAENNPKLKGLILCCSFISNPRSEMNPFEPFLPIVPIKLASTKIMISAVLGKFSNLTLCKSIQNAIQSIPVNIIRSRISAVMSVNVSDEFEKVTVPILYLRATHDWFVPNRISIDLTRRNSKVRIADIEGPHFLLQANPIVAANEIRSFLTEIQNAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYH0</accession>
    <name>A0A2S9GYH0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">PhnU2: putative 2-aminoethylphosphonate ABC transporter, permease protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_2505</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92775">
        <property type="protein sequence ID" value="PRC92775"/>
        <property type="gene ID" value="S2091_2505"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017664">
        <property type="entry name" value="AminoethylPonate_ABC_perm-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03262">
        <property type="entry name" value="PhnU2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="27"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="86"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="120"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="156"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="204"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="262"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="303"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="366"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="398"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="431"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="495"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="535"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="82"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="360"/>
            <end position="555"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC92775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="572" mass="62813" checksum="9BEB32C9004093F3" modified="2018-07-18" version="1">MKPAVKHHYSPLFFLRSTNVLRSTDELAASWIAAALALALLIFIGWPLMTMLMMTVKSADHHYIGLANWSAMVAEPRLRDATWNSVLLAVVTVCTVLPIALAFAFAITRTTMVWRNFFRVIALAPMLAPSLMPAISLVYLFGNQGLLKGWMGGSSIYGSIGIVMGEIFYTFPHALLILIAALSMADARLYEAAESLGASKLRRFWTITLPNARYGIVSAGMVVFTLVVTDFGVPKVIGGQINVLALEAYKQVIGQQNFSKGAVVGGMLLLPAVLSFAVEQWLSRHKSANMTGRSVVYKPSRNWLRDVVLFVLCAAVSIFVLALLGVAGAASFIKLWPYDMSLTWSHFDFDQLDGSGWQAFRNSMQLAFWTTLFGTSFIFITAYLLIKMPVPRAVATTIRSLAILPMAVPGMVLGLGYIFLFNDPVNPLHRLYGTMAILVIATIAHFYTTAHLTMVTTLRQIDAEIEAVARSLRRPWWFTMVRVTIPMSLPALLDVARYLFVSSMTTVSCVIFLYTPDTVLAGVAVLNMDDAGDTASAAAMASLIVVSSLLVTLLMNSAGRWLNRHGQAWRLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYN4</accession>
    <name>A0A2S9GYN4_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Uroporphyrinogen-III C-methyltransferase</fullName>
            <ecNumber evidence="2">2.1.1.107</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">S2091_2559</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="7">Porphyrin-containing compound metabolism; siroheme biosynthesis; precorrin-2 from uroporphyrinogen III: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the precorrin methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.107" evidence="2"/>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92829">
        <property type="protein sequence ID" value="PRC92829"/>
        <property type="gene ID" value="S2091_2559"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00262">
        <property type="reaction ID" value="UER00211"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004851">
        <property type="term" value="F:uroporphyrin-III C-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019354">
        <property type="term" value="P:siroheme biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd11642">
        <property type="entry name" value="SUMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1010.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000878">
        <property type="entry name" value="4pyrrol_Mease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035996">
        <property type="entry name" value="4pyrrol_Methylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014777">
        <property type="entry name" value="4pyrrole_Mease_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014776">
        <property type="entry name" value="4pyrrole_Mease_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006366">
        <property type="entry name" value="CobA/CysG_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003043">
        <property type="entry name" value="Uropor_MeTrfase_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00590">
        <property type="entry name" value="TP_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53790">
        <property type="entry name" value="SSF53790"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01469">
        <property type="entry name" value="cobA_cysG_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00839">
        <property type="entry name" value="SUMT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00840">
        <property type="entry name" value="SUMT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8 10" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 8 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TP_methylase" evidence="9">
        <location>
            <begin position="3"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC92829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="235" mass="24863" checksum="27A918D537C158D7" modified="2018-07-18" version="1">MGKVVLIGAGPGAADLITVRGARLLALAEVVLHDALVSQDMLDLCPQAIKVPVGKRFGKRSTAQAAINQQLVEYGLKHALVVRLKGGDPMLFGRADEELAALEQANIEVEVVPGISTAFAAAAATLQPLTKRGCARSVAFFTSSSAPELPETTQLPDCDTLVQYMGGQKALQTAEILLAQGRSPNLPVVIIENCSLPNQRIQRLKLADLQQGLEHCHGPVLVMIGEAFAARNSLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYN8</accession>
    <name>A0A2S9GYN8_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">dTTP/UTP pyrophosphatase</fullName>
            <shortName evidence="3">dTTPase/UTPase</shortName>
            <ecNumber evidence="3">3.6.1.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Nucleoside triphosphate pyrophosphatase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Nucleotide pyrophosphatase</fullName>
            <shortName evidence="3">Nucleotide PPase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_2548</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>H2O + UTP = diphosphate + H(+) + UMP</text>
            <dbReference type="Rhea" id="RHEA:29395"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="EC" id="3.6.1.9"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>dTTP + H2O = diphosphate + dTMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:28534"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37568"/>
            <dbReference type="ChEBI" id="CHEBI:63528"/>
            <dbReference type="EC" id="3.6.1.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the Maf family. YhdE subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.9" evidence="3"/>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92818">
        <property type="protein sequence ID" value="PRC92818"/>
        <property type="gene ID" value="S2091_2548"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036218">
        <property type="term" value="F:dTTP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035529">
        <property type="term" value="F:NADH pyrophosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036221">
        <property type="term" value="F:UTP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009117">
        <property type="term" value="P:nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00555">
        <property type="entry name" value="Maf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00528">
        <property type="entry name" value="Maf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029001">
        <property type="entry name" value="ITPase-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003697">
        <property type="entry name" value="Maf-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43213">
        <property type="entry name" value="PTHR43213"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02545">
        <property type="entry name" value="Maf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006305">
        <property type="entry name" value="Maf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52972">
        <property type="entry name" value="SSF52972"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00172">
        <property type="entry name" value="maf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 3" id="KW-0546">Nucleotide metabolism</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="87"/>
        </location>
    </feature>
    <feature type="site" description="Important for substrate specificity" evidence="3">
        <location>
            <position position="17"/>
        </location>
    </feature>
    <feature type="site" description="Important for substrate specificity" evidence="3">
        <location>
            <position position="88"/>
        </location>
    </feature>
    <feature type="site" description="Important for substrate specificity" evidence="3">
        <location>
            <position position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC92818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="207" mass="22861" checksum="C6D75B2A5E94D7F7" modified="2018-07-18" version="1">MMKLLDNKIYLASKSPRRRELLRQIGVNFEILLLRDSATRPVDVSETVLPDELPAAYVTRVTNAKAEAAWDMMELRKLPIRPVLAADTTVVLNGVIYGKPANRSEAHAMLTSLSGQTHQVLTSIAVHYKKQHLEFTQTSAVTFCTLNKNQLDQYCDSLEPYDKAGGYGIQGSAAKFISHIDGSYSGIMGLPLFETAKLLTEVGLTFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYW2</accession>
    <name>A0A2S9GYW2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Amidohydrolase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2307</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92890">
        <property type="protein sequence ID" value="PRC92890"/>
        <property type="gene ID" value="S2091_2307"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="SSF51338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015504023" evidence="1">
        <location>
            <begin position="24"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="domain" description="Amidohydro-rel" evidence="2">
        <location>
            <begin position="352"/>
            <end position="437"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="466" mass="50282" checksum="722109750FB4A643" modified="2018-07-18" version="1">MAYKTRKLAVMISLLCLIQTTYAAETTTSGLSKEELVTAKLAGKATGKVIYLGATVITGNESKSDMAIVVNGERIEAIIPAAQVNSASLTETEIVDVHHLFVLPGLIDSHVHYGTHPNLSFAQAQLKRDVYAGITGVRDMAGDARFLGDMSRASLINEIPAPDIYYASLVAGPSFFNDPRTVTSALGMPPGTAPWMYAVTDKTNMAMTLSQARGTGATGLKIYANLPGPLVQRLVKEANHQHFPVWTHLQVYPATPYDSLGATSVSHVCMIARYAAQPGKAKYGHQNEPSYDDMSANNAEIKKYISALKKSGTIMDATLSVYELPSQAKVTADGKTKHLHCSIELAGEITHAMLVAGIPIVAGTDSNASADDAFPALNRELEYLVKYAGLSAREAILSATENAAKALGKEKEIGSIETGKFANLVFTKEDPTQDIAHLRSIEFTVKRGIRFDRKDYQHQPIPEQDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZ59</accession>
    <name>A0A2S9GZ59_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2432</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC93015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93015">
        <property type="protein sequence ID" value="PRC93015"/>
        <property type="gene ID" value="S2091_2432"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043727">
        <property type="entry name" value="DUF5670"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18919">
        <property type="entry name" value="DUF5670"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="26"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="49" mass="5416" checksum="67776C420FEDD61F" modified="2018-07-18" version="1">MLYTIALILVILWLLGLVTSYTLGGFIHILLVIAIVVILLRVINGRTPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZ80</accession>
    <name>A0A2S9GZ80_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Putative NADH dehydrogenase/NAD(P)H nitroreductase S2091_2353</fullName>
            <ecNumber evidence="5">1.-.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_2353</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the nitroreductase family. HadB/RutE subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.-.-.-" evidence="5"/>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92936">
        <property type="protein sequence ID" value="PRC92936"/>
        <property type="gene ID" value="S2091_2353"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02148">
        <property type="entry name" value="RutE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.109.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01204">
        <property type="entry name" value="Oxidoreductase_RutE_HadB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029479">
        <property type="entry name" value="Nitroreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000415">
        <property type="entry name" value="Nitroreductase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023936">
        <property type="entry name" value="RutE-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00881">
        <property type="entry name" value="Nitroreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55469">
        <property type="entry name" value="SSF55469"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2 5" id="KW-0288">FMN</keyword>
    <keyword evidence="5" id="KW-0520">NAD</keyword>
    <keyword evidence="3 5" id="KW-0521">NADP</keyword>
    <keyword evidence="4 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nitroreductase" evidence="6">
        <location>
            <begin position="15"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC92936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="193" mass="21020" checksum="BF4550DAC7120B10" modified="2018-07-18" version="1">MLDKAALATLFTEARTHNVWLNKPVSDELCQQIYDLAKWGATSANCSPARIVFVKSAAEKEKLVACLSPGNQEKTKAAPVTAIIAMDMEFYEKLPQLFPHADARSWFVGNQPNIDATAFRNGTLQGGYLMLAARALGLDCGPMSGFDADKVNAAFFAGSSLKVNFICNFGYGDAAQLFPRSPRLTFEEACRIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZF6</accession>
    <name>A0A2S9GZF6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2174</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93088">
        <property type="protein sequence ID" value="PRC93088"/>
        <property type="gene ID" value="S2091_2174"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014859">
        <property type="entry name" value="Phage_TAC_4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08748">
        <property type="entry name" value="Phage_TAC_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="103" mass="11618" checksum="2C1BDAF1E8696CAD" modified="2018-07-18" version="1">MAKLTLQPKPEFKGTVEIPSAGDGLVTIEVTFIHRTKTQLDEFIKTRTGVDDHVSFMDMVSGWDLKDKFNEDNVKLLLENYISAAQVTFQRYVALLVDGKAKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZG8</accession>
    <name>A0A2S9GZG8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative gamma-carboxymuconolactone decarboxylase subunit.like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2210</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93124">
        <property type="protein sequence ID" value="PRC93124"/>
        <property type="gene ID" value="S2091_2210"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051920">
        <property type="term" value="F:peroxiredoxin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029032">
        <property type="entry name" value="AhpD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003779">
        <property type="entry name" value="CMD-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02627">
        <property type="entry name" value="CMD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69118">
        <property type="entry name" value="SSF69118"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CMD" evidence="1">
        <location>
            <begin position="39"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="133" mass="14266" checksum="41C0CC1FBC27E69D" modified="2018-07-18" version="1">MTAPLRSISETTLRGQRLMDTLEPGLSVRVGDRLSELDPGLERLVTDYAFGDVLSRPGLDIKTREMLTVAALTAMGNAPGQLELHMRGALNVGVTRAKLLEIVIQMALYAGLPACMNGVTAYRAVLAAADQNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZH0</accession>
    <name>A0A2S9GZH0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phage-related protein tail component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2186</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93100">
        <property type="protein sequence ID" value="PRC93100"/>
        <property type="gene ID" value="S2091_2186"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010654">
        <property type="entry name" value="Phage_lambda_tail_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06805">
        <property type="entry name" value="Lambda_tail_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="188" mass="19836" checksum="E33A4083977EA2BC" modified="2018-07-18" version="1">MNQLRTIRLYGKLGNQFGRVHTLAVANVREAVKALSVLLPGFERELLTSKARGIVYAVFIGKKNISKDDLHQPTGSNDIRIAPILQGAKRGGILQTIVGAVLVVVGTYFGQAWAVQAGIGMMLGGVVQMLSPQQLGQSGKDDPANAASYNFNGAVNTTAQGNPVPILYGRMIVGSAVISAGIYSEDKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZI0</accession>
    <name>A0A2S9GZI0_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Abasic site processing protein</fullName>
            <ecNumber evidence="7">3.4.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_2196</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the SOS response-associated peptidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.-.-" evidence="7"/>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93110">
        <property type="protein sequence ID" value="PRC93110"/>
        <property type="gene ID" value="S2091_2196"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006974">
        <property type="term" value="P:cellular response to DNA damage stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018142">
        <property type="term" value="P:protein-DNA covalent cross-linking"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1680.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003738">
        <property type="entry name" value="SRAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036590">
        <property type="entry name" value="SRAP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13604">
        <property type="entry name" value="PTHR13604"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02586">
        <property type="entry name" value="SRAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143081">
        <property type="entry name" value="SSF143081"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0190">Covalent protein-DNA linkage</keyword>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 7" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU364100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC93110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="226" mass="25380" checksum="58FDD128A3BA3486" modified="2018-07-18" version="1">MCVNFITPSHQQLKTHFKAPIAASAEWKTAVWQDYAAPIIVGDEHERQSLLGLYSMIPKSHLPPGTKRFSTMNARAETVATLRSYAQPWRDGQLCLVPMTTFFEPCYESGKAERWKIGMADESPFAVAGLYRSWTETDGGTSFSFTQLTINADEHPLMRRFHKPGDEKRSLVILPESAYGDWLGCRDSERAKAFLKHSSNEHLVAYPVPKVAISKPKSTSNLGLFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZL6</accession>
    <name>A0A2S9GZL6_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 8">Phosphoglucosamine mutase</fullName>
            <ecNumber evidence="6 8">5.4.2.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">glmM</name>
        <name evidence="13" type="ORF">S2091_2234</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 8">Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 8">
            <text>alpha-D-glucosamine 1-phosphate = D-glucosamine 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:23424"/>
            <dbReference type="ChEBI" id="CHEBI:58516"/>
            <dbReference type="ChEBI" id="CHEBI:58725"/>
            <dbReference type="EC" id="5.4.2.10"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="6">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="PTM">
        <text evidence="6">Activated by phosphorylation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the phosphohexose mutase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.2.10" evidence="6 8"/>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93148">
        <property type="protein sequence ID" value="PRC93148"/>
        <property type="gene ID" value="S2091_2234"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008966">
        <property type="term" value="F:phosphoglucosamine mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05802">
        <property type="entry name" value="GlmM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01554_B">
        <property type="entry name" value="GlmM_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005844">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016055">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I/II/III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005845">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005846">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005843">
        <property type="entry name" value="A-D-PHexomutase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036900">
        <property type="entry name" value="A-D-PHexomutase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016066">
        <property type="entry name" value="A-D-PHexomutase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005841">
        <property type="entry name" value="Alpha-D-phosphohexomutase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006352">
        <property type="entry name" value="GlmM_bact"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02878">
        <property type="entry name" value="PGM_PMM_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02879">
        <property type="entry name" value="PGM_PMM_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02880">
        <property type="entry name" value="PGM_PMM_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00408">
        <property type="entry name" value="PGM_PMM_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00509">
        <property type="entry name" value="PGMPMM"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53738">
        <property type="entry name" value="SSF53738"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55957">
        <property type="entry name" value="SSF55957"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01455">
        <property type="entry name" value="glmM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00710">
        <property type="entry name" value="PGM_PMM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4 6 7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 6 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PGM_PMM_I" evidence="10">
        <location>
            <begin position="3"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_II" evidence="11">
        <location>
            <begin position="161"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_III" evidence="12">
        <location>
            <begin position="262"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_IV" evidence="9">
        <location>
            <begin position="376"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="active site" description="Phosphoserine intermediate" evidence="6">
        <location>
            <position position="106"/>
        </location>
    </feature>
    <feature type="binding site" description="via phosphate group" evidence="6">
        <location>
            <position position="106"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="245"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="247"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="249"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="Phosphoserine" evidence="6">
        <location>
            <position position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004327"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PRC93148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="447" mass="47970" checksum="9650B57CCEC90AB2" modified="2018-07-18" version="1">MKRKYFGTDGIRGKVGAAPITPDFVMRLGYAAGKVLAQVSHQESNRPTVLIGKDTRISGYMLEAALQAGFAAAGVDVVLAGPMPTPAIAYLTRALRLNAGVVISASHNPFDDNGIKFFSAQGTKLPDQVELEIEANLELEMHCVPSEKLGKARRLDDAPGRYIEFCKSSFPNELDLRGLKIVVDCAHGAAYHIAPHVLHELGAEVIAIGNQPNGININDQVGATDTAALSQAVQHHHADLGIALDGDADRLMMTDATGRVYNGDELLYLMATDRLAQGSLSGVVGTLMTNMALEVAFEELGVPFARAKVGDRYVLELMRERGWILGGEGSGHLLCLDQHSTGDGIISALQVLSALRRHNKTLPEFFTGISMFPQALVNVRVVAGTDWQKNAAMVADKALVEAELGKNGRVLIRASGTEPLIRVMVEARQDELAQQMAKRLAAHLSGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZM6</accession>
    <name>A0A2S9GZM6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2267</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93181">
        <property type="protein sequence ID" value="PRC93181"/>
        <property type="gene ID" value="S2091_2267"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12802">
        <property type="entry name" value="MarR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00347">
        <property type="entry name" value="HTH_MARR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50995">
        <property type="entry name" value="HTH_MARR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="1">
        <location>
            <begin position="9"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="137" mass="15681" checksum="93E7B1BAAA27861E" modified="2018-07-18" version="1">MKNSSKDLSKQDFEALSTFRYQLRKFLRFSEEAAQSEGVTPQQYLLLLHVKGIAGRDWANIGELAERLQSQHHSVVALVTRCEKLELIERRTSEVDRRQVNIHLLPAGERCLAKLAELHRNELATLSGIFRIPTINS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZT0</accession>
    <name>A0A2S9GZT0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Adenosylmethionine-8-amino-7-oxononanoate aminotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1946</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93208">
        <property type="protein sequence ID" value="PRC93208"/>
        <property type="gene ID" value="S2091_1946"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00610">
        <property type="entry name" value="OAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000521">
        <property type="entry name" value="Transaminase_4ab_Lys_Orn"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00600">
        <property type="entry name" value="AA_TRANSFER_CLASS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="1 2" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="484" mass="52852" checksum="549503A170FA45EB" modified="2018-07-18" version="1">MYSNKSDPIAIVTPSIRASDVQKKYDTRAIQELDAAHYIHSFTDTKALASVGARVIVKGQGIYIWDSEGKRLLDGMSGLWCMNVGYGRKSIADAVYVQMQELPYYNSFFQTTNAPAAQLAAKLVEISPPQFNHVFFTGSGSEGNDTNIRMVRRYWDLLGFKERNVIISRHNAYHGSTIAGASLGGMSGMHDQQIGIAIPNIVHIGQPYYVEGGKGKTPEEFGLEAAGWLEQKILEVGAEKVAAFIGEPVQGAGGVIIPPSTYWPEIQRICDRYGILLIADEVICGFGRLGHWFGSEYFGIKPDLMTFAKGVTSGYIPLGGVMVGDRVADVLIEKGGDFNHGFTYSGHPVACAAALENIRIIQEEQLVEKVRNETGPYLKKKFATLADHPLVSVAETCGFAAGLNLVQKKGATVHDCVPFDSKLEVGMICRGHMFGNGMIMRAVGDRMIIAPPLVTTIAEIDEMIELIRHCLDATLADLKARELM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZV9</accession>
    <name>A0A2S9GZV9_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">tRNA pseudouridine synthase A</fullName>
            <ecNumber evidence="4">5.4.99.12</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">tRNA pseudouridine(38-40) synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">tRNA pseudouridylate synthase I</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">tRNA-uridine isomerase I</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">truA</name>
        <name evidence="9" type="ORF">S2091_2242</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4 7">
            <text>uridine(38/39/40) in tRNA = pseudouridine(38/39/40) in tRNA</text>
            <dbReference type="Rhea" id="RHEA:22376"/>
            <dbReference type="Rhea" id="RHEA-COMP:10085"/>
            <dbReference type="Rhea" id="RHEA-COMP:10087"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="EC" id="5.4.99.12"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4 7">Belongs to the tRNA pseudouridine synthase TruA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.12" evidence="4"/>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93156">
        <property type="protein sequence ID" value="PRC93156"/>
        <property type="gene ID" value="S2091_2242"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106029">
        <property type="term" value="F:tRNA pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031119">
        <property type="term" value="P:tRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02570">
        <property type="entry name" value="PseudoU_synth_EcTruA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.580">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.660">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00171">
        <property type="entry name" value="TruA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001406">
        <property type="entry name" value="PsdUridine_synth_TruA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020097">
        <property type="entry name" value="PsdUridine_synth_TruA_a/b_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020095">
        <property type="entry name" value="PsdUridine_synth_TruA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020094">
        <property type="entry name" value="TruA/RsuA/RluB/E/F_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11142">
        <property type="entry name" value="PTHR11142"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01416">
        <property type="entry name" value="PseudoU_synth_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001430">
        <property type="entry name" value="tRNA_psdUrid_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00071">
        <property type="entry name" value="hisT_truA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4 7" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="PseudoU_synth_1" evidence="8">
        <location>
            <begin position="11"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="domain" description="PseudoU_synth_1" evidence="8">
        <location>
            <begin position="151"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4 5">
        <location>
            <position position="54"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4 6">
        <location>
            <position position="118"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR001430-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR001430-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC93156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="269" mass="30491" checksum="783D8EC9C5EDC007" modified="2018-07-18" version="1">MQLKRIVLGVQYDGRPWLGWQSQPNGQTVQDMLEKALQSIATQPVKVSCAGRTDAGVHALEQVVHFDTDIDRSLTSWVRGVNAHLPESIAVRWSSEIAQASEPELEFHARFSARARTYHYVLYNHPVRSPLLSGRVGWVFRPLDEQKMQDAAQYLVGEHDFSAFRATTCQAKSPVKTMHEITLQRQGNFIFLTLRASAFLHHMVRNIVGSLIAVGVGKYEPEWMQEVLQTADRSISAPTFMPDGLYLAKVDYDPKWNLPQQISSLNWFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZX8</accession>
    <name>A0A2S9GZX8_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">TsaA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_2019</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the tRNA methyltransferase O family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93281">
        <property type="protein sequence ID" value="PRC93281"/>
        <property type="gene ID" value="S2091_2019"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09281">
        <property type="entry name" value="UPF0066"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023370">
        <property type="entry name" value="TrmO-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040372">
        <property type="entry name" value="YaeB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036413">
        <property type="entry name" value="YaeB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036414">
        <property type="entry name" value="YaeB_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12818">
        <property type="entry name" value="PTHR12818"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01980">
        <property type="entry name" value="TrmO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118196">
        <property type="entry name" value="SSF118196"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51668">
        <property type="entry name" value="TSAA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="TsaA-like" evidence="3">
        <location>
            <begin position="5"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00033753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC93281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="157" mass="18026" checksum="30E0E8D944559E74" modified="2018-07-18" version="1">MDIQIQSIGVVDAIRPHAEDDFWGGEESCITLSDQFEPEALLGLSEFSHIEIIFLFHEVDPAKIVFGARHPRNNLNWPKVGIFAQRGKNRPNRLGSTICRLIRVHGNQLFVSELDAINETPIVDIKPVMSEFLPRHDVSQPKWSHEIMNEYWLEKAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H064</accession>
    <name>A0A2S9H064_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">LysR substrate binding domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2095</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93357">
        <property type="protein sequence ID" value="PRC93357"/>
        <property type="gene ID" value="S2091_2095"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08417">
        <property type="entry name" value="PBP2_Nitroaromatics_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037402">
        <property type="entry name" value="YidZ_PBP2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="6"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="326" mass="36300" checksum="2A3E867164C22FD4" modified="2018-07-18" version="1">MNFLTLDLNLLRVFDAVMIEQNLTRAADKLAMTQPAVSNAVKRLRHAFNDELLIRTVYGVKPTPRAESIWPAIREALSKLEAAIAPPTFDPASASASFRMAMADSTAAYWMPHLVREIEKCAPGINARMVPLVTRDPRSMLLQGDIDIAVGFFPGVVSQLAGGQSSANSPIRHASLYTGRYVCVMRKDHPLANTPLTLETYCNAHHLLVSFSGRAHGLIDEILMPMKLQRHIILTVNQFFTAGRVVANSDLLTVLPQHLISSTGMANQLIWKELPISTPAVNVDMLWHEREARNPAHKWLRENLINLVEQTLNSENPQIEHQNALL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H095</accession>
    <name>A0A2S9H095_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">S2091_1757</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93370">
        <property type="protein sequence ID" value="PRC93370"/>
        <property type="gene ID" value="S2091_1757"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004673">
        <property type="term" value="F:protein histidine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="26"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="181"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="9">
        <location>
            <begin position="201"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="8">
        <location>
            <begin position="309"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="270"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC93370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="547" mass="59516" checksum="EEB4E398927F5947" modified="2018-07-18" version="1">MRPDFISVQLINTQGPHLKLTLTSKLMAAVLLAFAMLCTGDYLISYRTLESTVLKNILTTVSQSSQLINAAVASAANGHENKNGLHTLQTFFSEMLTPNGNSGIVYIAVLRADGTVIMNTSATQVSLPAPDLPENYAAAAKRGMLHVRDNVLLENNEVGFLQYGLATGDLMEAMAQSQRNSLILTTIVILLSFVALSLFGLKITRQLSALKHATQEIADGHYELKMPEIGDDELGEVAHNFNLMSEAIAAKVREVSTLNHELEQRVDQRTSDLHLANQKLEENIKELESTRDSLVKSEKLASLGAIVAGVAHEINTPIGNALVTASTIREIVDGFSAQAATGKMTHSALNNFLNQCKEGSHLVEHSLARASELIQSFKQVAVDQSSERRRSFNLAEMVRETITTLRHIYKNTNFTLENDIQANIVMDSFPGALGQVITNLLNNALIHGFEGREQGKMLISAERLVNNSVRICFSDNGNGIAVSNLKRIFDPFFTTKFGQGGSGLGLNVVDNIVHRILGGSVYVDSQIGFGTIFTIEIPLNAPFVEAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0A6</accession>
    <name>A0A2S9H0A6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Bacterial Cytochrome Ubiquinol Oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">S2091_1767</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Cell inner membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the cytochrome ubiquinol oxidase subunit 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93380">
        <property type="protein sequence ID" value="PRC93380"/>
        <property type="gene ID" value="S2091_1767"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070069">
        <property type="term" value="C:cytochrome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019646">
        <property type="term" value="P:aerobic electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002585">
        <property type="entry name" value="Cyt-d_ubiquinol_oxidase_su_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30365">
        <property type="entry name" value="PTHR30365"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01654">
        <property type="entry name" value="Cyt_bd_oxida_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006446">
        <property type="entry name" value="Cyt_quinol_oxidase_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 12" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 12" id="KW-0249">Electron transport</keyword>
    <keyword evidence="5 12" id="KW-0349">Heme</keyword>
    <keyword evidence="10 12" id="KW-0408">Iron</keyword>
    <keyword evidence="11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 12" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="55"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="94"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="128"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="185"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="216"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="387"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="420"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="470"/>
            <end position="491"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRNR" id="PIRNR006446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PRC93380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="524" mass="58338" checksum="957EE9C0573B5DAF" modified="2018-07-18" version="1">MIDEVVALSRLQFAATAMYHFLFVPLTLGLSWILVIMEATYLMTGREIYRDMTKFWGKLFGINFAMGVTTGITLEFQFGTNWAYYSHYVGDIFGVPLAVEGMMAFFLESTFVGLFFFGWSRLSRVQHFGVTCLVALGSSLSALWILIANGWMNNPVGAEFNFTTMRMELTSIQEVIFNPVAQVKFVHTIAAGYVTASMFVLGISAFYLLRARDTAFALRSFAIAAGFGLAATLSVIVLGDESGYTAGEVNKVKLAAIEAEWETQPAPAGITLFGWPNDKTERTDYAIKIPYVLGLIATRSVDTEVKGIKDLKKEHEVRIQNGMLAYGALVRLKAGDLSARPEFEQTQHDLGYGLLLKKYTDNVVDATPAQITKAVNDTIPKVAPLFWSFRLMVALGFLFLFIFSCSFYLLIRKKLAENRWLLKLAVVSIPLPWIAAELGWFTAEYGRQPWTIAGILPTHLSVSNLPASSLYASLAGFIVFYTLLLIIELFLMQKYIRLGPSSLHTGKYHFETKVATNLPTKDAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0C7</accession>
    <name>A0A2S9H0C7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1787</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93400">
        <property type="protein sequence ID" value="PRC93400"/>
        <property type="gene ID" value="S2091_1787"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="76" mass="8676" checksum="AFB30C906F5506BF" modified="2018-07-18" version="1">MLMVTLCLCQLFITYTPVYAYQKMTSRPTSDYADILFRNDEFRIDQTAIFLYSHQIIAIAIQNGSIRISVATAYAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0E5</accession>
    <name>A0A2S9H0E5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ATPase family associated with various cellular activities (AAA)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1842</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93455">
        <property type="protein sequence ID" value="PRC93455"/>
        <property type="gene ID" value="S2091_1842"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="1">
        <location>
            <begin position="239"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="448" mass="50821" checksum="DF8D58260C4B310F" modified="2018-07-18" version="1">MTDHINTDALEREITWFSQVCDARFDAYFKQSEFDIDLETLCPAPALNQEDSPYAQIVGELKMNYAERIVLMLALMPHVRPQALDLFSLQNSALGRPYSEIGGWRGKSHIGFLPTCETASFILVGNNLSKRFMVARLFKDDHFFTRQGIIKLDHQANGEPFFDAALQLSYEYLQRLADGEVHKPDFSANFPAKLMQTQLNWSDLVLNPDVMDEVENIVTWLRNPGHIIENWGLGKSLKPGYRTMFYGPPGTGKTLTASLIGKIVGSDVYRIDLSMVVSKYIGETEKNLANVFDQAQNKNWILFFDEADSLFGKRTQASSSNDRHANQETSYLLQRVEDFPGVVILATNLKANIDAAFSRRFQSEVYFAMPDALQRERLWHGLFAQTDKLDKDVNFHEIAERYELAGGALLNVARYAAIRAVRNQRDVINQEDLLAGIGRELMKDGKTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H124</accession>
    <name>A0A2S9H124_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1682</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93681">
        <property type="protein sequence ID" value="PRC93681"/>
        <property type="gene ID" value="S2091_1682"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027396">
        <property type="entry name" value="DsrEFH-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003787">
        <property type="entry name" value="Sulphur_relay_DsrE/F-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02635">
        <property type="entry name" value="DrsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75169">
        <property type="entry name" value="SSF75169"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015592441" evidence="1">
        <location>
            <begin position="32"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="152" mass="16381" checksum="9449785A6335476D" modified="2018-07-18" version="1">MNKLFSIRRTILFNSLALAGIGLLSAKQSSAAQNNSDSSTFKTVFQVSDADPQKWQLTLANAKNLQIDLGEKNGSIEIVAYGPGIAMFKAESEVAPQVLQAMQAGVLIRVCENSMHGQHLKHEDMISAVGFVPSGVGELVRRQAAGYAYIRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H136</accession>
    <name>A0A2S9H136_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Cytokinin riboside 5'-monophosphate phosphoribohydrolase</fullName>
            <ecNumber evidence="2">3.2.2.n1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1661</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>AMP + H2O = adenine + D-ribose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:20129"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16708"/>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="3.2.2.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the LOG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.2.n1" evidence="2"/>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93660">
        <property type="protein sequence ID" value="PRC93660"/>
        <property type="gene ID" value="S2091_1661"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008714">
        <property type="term" value="F:AMP nucleosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009691">
        <property type="term" value="P:cytokinin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005269">
        <property type="entry name" value="LOG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031100">
        <property type="entry name" value="LOG_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03641">
        <property type="entry name" value="Lysine_decarbox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00730">
        <property type="entry name" value="TIGR00730"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0203">Cytokinin biosynthesis</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU363015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="243" mass="27010" checksum="BD265BDEF4C157C2" modified="2018-07-18" version="1">MSENRKNILKLRQVTDQQRSTTVKASESWNLLTIMAEFIESTERLSEVRPAVTIFGSARTKPDDPFYLNCVDLSRRLSDAGFSVISGGGPGIMEAANKGAFAGASSSIGLNVELPREQKPNPWQDISISFRHFFARKVAFVKYADAYVIYPGGFGTLDEMTEVLTLIQTGKSRHIPVILVGTQFWSGLLDWLHSALLGNQMIAEKDLELIQLIDEPSNIIDAIFAFYEAQDIEAVDDGLHRLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H158</accession>
    <name>A0A2S9H158_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cytochrome-c oxidase</fullName>
            <ecNumber evidence="3">7.1.1.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Cytochrome aa3 subunit 3</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Cytochrome c oxidase polypeptide III</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">S2091_1698</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the cytochrome c oxidase subunit 3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.1.1.9" evidence="3"/>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93697">
        <property type="protein sequence ID" value="PRC93697"/>
        <property type="gene ID" value="S2091_1698"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004129">
        <property type="term" value="F:cytochrome-c oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019646">
        <property type="term" value="P:aerobic electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01665">
        <property type="entry name" value="Cyt_c_Oxidase_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024791">
        <property type="entry name" value="Cyt_c/ubiquinol_Oxase_su3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033945">
        <property type="entry name" value="Cyt_c_oxase_su3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000298">
        <property type="entry name" value="Cyt_c_oxidase-like_su3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035973">
        <property type="entry name" value="Cyt_c_oxidase_su3-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013833">
        <property type="entry name" value="Cyt_c_oxidase_su3_a-hlx"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11403">
        <property type="entry name" value="PTHR11403"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00510">
        <property type="entry name" value="COX3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81452">
        <property type="entry name" value="SSF81452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50253">
        <property type="entry name" value="COX3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="19"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="45"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="83"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="184"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="222"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="267"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="domain" description="COX3" evidence="11">
        <location>
            <begin position="7"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00031400"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031625"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PRC93697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="286" mass="32101" checksum="86E851EBAC0A4433" modified="2018-07-18" version="1">MSSGHAKAPYYFVPGPSQWPFLAGATLLLTMLGAAAWVNSLPYAMYVNFAGIFLTLVVLYFWFGDAIKESEGGQYNARVDLSYRWSMSWFIFSEVMFFGAFFGALFYARSISMPWLADLDNKVLWPDFVGHWGNIGPAGTIETFKLMGPFPIPTINTALLLSSGVTLTIAHHALIAGHRAKTSLFLFATILLGATFMGLQGYEYMHAYTELNLKLTSGIYGSTFFLLTGFHGFHVTMGAIMLSVVLYRHLKGHFTPTHHFAFEGAAWYWHFVDVVWLGLYVVVYWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1A7</accession>
    <name>A0A2S9H1A7_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Apolipoprotein N-acyltransferase</fullName>
            <shortName evidence="9">ALP N-acyltransferase</shortName>
            <ecNumber evidence="9">2.3.1.269</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">lnt</name>
        <name evidence="11" type="ORF">S2091_1749</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>a glycerophospholipid + N-terminal S-1,2-diacyl-sn-glyceryl-L-cysteinyl-[lipoprotein] = a 2-acyl-sn-glycero-3-phospholipid + H(+) + N-acyl-S-1,2-diacyl-sn-glyceryl-L-cysteinyl-[lipoprotein]</text>
            <dbReference type="Rhea" id="RHEA:48228"/>
            <dbReference type="Rhea" id="RHEA-COMP:14681"/>
            <dbReference type="Rhea" id="RHEA-COMP:14684"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:136912"/>
            <dbReference type="ChEBI" id="CHEBI:140656"/>
            <dbReference type="ChEBI" id="CHEBI:140657"/>
            <dbReference type="ChEBI" id="CHEBI:140660"/>
            <dbReference type="EC" id="2.3.1.269"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="9">Protein modification; lipoprotein biosynthesis (N-acyl transfer).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.269" evidence="9"/>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93748">
        <property type="protein sequence ID" value="PRC93748"/>
        <property type="gene ID" value="S2091_1749"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00666"/>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016410">
        <property type="term" value="F:N-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042158">
        <property type="term" value="P:lipoprotein biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07571">
        <property type="entry name" value="ALP_N-acyl_transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01148">
        <property type="entry name" value="Lnt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004563">
        <property type="entry name" value="Apolipo_AcylTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003010">
        <property type="entry name" value="C-N_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036526">
        <property type="entry name" value="C-N_Hydrolase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045378">
        <property type="entry name" value="LNT_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00795">
        <property type="entry name" value="CN_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20154">
        <property type="entry name" value="LNT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56317">
        <property type="entry name" value="SSF56317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00546">
        <property type="entry name" value="lnt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50263">
        <property type="entry name" value="CN_HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9 11" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3 9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="11" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9 11" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="12"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="34"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="62"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="89"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="120"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="165"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="195"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="486"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="domain" description="CN hydrolase" evidence="10">
        <location>
            <begin position="227"/>
            <end position="473"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC93748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="510" mass="57284" checksum="015A931D77B35253" modified="2018-07-18" version="1">MQSVISRCPNWVLFLCAFLAGGLNVLAFAPIGYWPLQLLSLSALFCVLYVENDIKKIMKTTWLYCFSWLFFGVIWLTVTMFRYGDMPVWLAVFAVFLFTGAIACIPVLFMGLAARYKAHFSPAVICLVWFPTLWSLAEWTRDWLFTGFPWLVSGYAHNASPLAGYAPIIGVFGITWLTAIFAGSVVLFLDGKRSFSAVAVGIFLLGGALQYVSWTTPSGAPLTVRLLQGNVDQAIKFEQEHLIDSLRFYYDAILKKPADLIVTPESALPLPMQFLPPEYLPDLQKFATQTNSHIALGMFSSDGPNLYANSMIGITPTPQKTTYRYDKHHLVPFGEFIPWGFGWFYHFMNIPMGDQQRGALLAAPFAVKDQQILPNICYEDVFGEEIAAKIAHAYFTQQAMPTILLNMTNLAWFGDSWAMPQHVQITQMRTLEMGRPMLRSTNTGVTTLVNAQGQIVKQLAPFVRGELDVSVQGYQGLTPYIVCGNYLWLGLMSLLALVTACSYFWKKRVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1F1</accession>
    <name>A0A2S9H1F1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1418</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93809">
        <property type="protein sequence ID" value="PRC93809"/>
        <property type="gene ID" value="S2091_1418"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="59" mass="6513" checksum="1F3A042A95BEFA9C" modified="2018-07-18" version="1">MQLESRDEVAVEVAVEVEVEVEVEVEVEVEVGVEVGVEVAVEVDLPPLLIRPVFLRKKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1Q3</accession>
    <name>A0A2S9H1Q3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Acyl carrier protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_1482</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93873">
        <property type="protein sequence ID" value="PRC93873"/>
        <property type="gene ID" value="S2091_1482"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="4">
        <location>
            <begin position="15"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="3">
        <location>
            <position position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC93873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="95" mass="10707" checksum="1A55515D9DB89150" modified="2018-07-18" version="1">MKNSLYTSQNTGAGILVTDLRDQVRRYLAEYFMTDDMPGDEELLVEDLGADSLDLLQVAHNLNDMFDINIDTESLPDMLMVGSACDLVERLRYGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1X3</accession>
    <name>A0A2S9H1X3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">IS66 Orf2 like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1157</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC93984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93984">
        <property type="protein sequence ID" value="PRC93984"/>
        <property type="gene ID" value="S2091_1157"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008878">
        <property type="entry name" value="Transposase_IS66_Orf2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36455">
        <property type="entry name" value="PTHR36455"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05717">
        <property type="entry name" value="TnpB_IS66"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="97" mass="10851" checksum="613DE2F904619BE0" modified="2018-07-18" version="1">MRAGFNGLAAKVETALEDDPFSGHVFLFRGRRGNVIKVLWSTGDGLCLLSKRLEQGRFIWPQADSGKVHLTQAQLSMLLEGIDWKQPKHTQPAMTML</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1Z8</accession>
    <name>A0A2S9H1Z8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1172</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC93999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93999">
        <property type="protein sequence ID" value="PRC93999"/>
        <property type="gene ID" value="S2091_1172"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.428.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019808">
        <property type="entry name" value="Histidine_triad_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001310">
        <property type="entry name" value="Histidine_triad_HIT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011146">
        <property type="entry name" value="HIT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036265">
        <property type="entry name" value="HIT-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23089">
        <property type="entry name" value="PTHR23089"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01230">
        <property type="entry name" value="HIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00332">
        <property type="entry name" value="HISTRIAD"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54197">
        <property type="entry name" value="SSF54197"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00892">
        <property type="entry name" value="HIT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51084">
        <property type="entry name" value="HIT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HIT" evidence="2">
        <location>
            <begin position="5"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Histidine triad motif" evidence="1">
        <location>
            <begin position="107"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="126" mass="13705" checksum="25D290F4E976379B" modified="2018-07-18" version="1">MENCLFCKIAAGTVPAQKVYEDAEFLAFNDIFPAAPIHLLIIPKHHVATLSDCTSSDTELLGRMLALVPKLAEQQGCHVQLDDAGNRIGGYKTLINSGPDGGQEVYHLHVHVIGGPRPWHGKNIQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H269</accession>
    <name>A0A2S9H269_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1231</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94058">
        <property type="protein sequence ID" value="PRC94058"/>
        <property type="gene ID" value="S2091_1231"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="92" mass="10041" checksum="24FA6D7496DBB499" modified="2018-07-18" version="1">MTTRITVAADNARIGDIIYNGLGSGKHPTYSWEAITQVNSVDGLIQLITGRLDGPHGEFWFEPEESVVVVRHPPAAPKPAIAEPHNKRPHGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H282</accession>
    <name>A0A2S9H282_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1268</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94095">
        <property type="protein sequence ID" value="PRC94095"/>
        <property type="gene ID" value="S2091_1268"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="143"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="144"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="164" mass="18392" checksum="4B43FCFB94BEDCB7" modified="2018-07-18" version="1">MTSSDLAALTNLARIGKLKIEPPDARELAGLLRSATARWHDSKQTILSIESRFDLAYNAAHAAALSALRFHGYRSENRYLVFQCLEHTLGHQPAQWLLLNQAHNKRNLAEYEGDLDVTLSFVEELIEHVGNIIAAAHELHLQSPPRSAINSRPNPNQNMSSKRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2E7</accession>
    <name>A0A2S9H2E7_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9 10">Chromosomal replication initiator protein DnaA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">dnaA</name>
        <name evidence="14" type="ORF">S2091_1209</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9 10">Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9 11">Belongs to the DnaA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94036">
        <property type="protein sequence ID" value="PRC94036"/>
        <property type="gene ID" value="S2091_1209"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003688">
        <property type="term" value="F:DNA replication origin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006275">
        <property type="term" value="P:regulation of DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06571">
        <property type="entry name" value="Bac_DnaA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1750.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00377">
        <property type="entry name" value="DnaA_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001957">
        <property type="entry name" value="Chromosome_initiator_DnaA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020591">
        <property type="entry name" value="Chromosome_initiator_DnaA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018312">
        <property type="entry name" value="Chromosome_initiator_DnaA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013317">
        <property type="entry name" value="DnaA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013159">
        <property type="entry name" value="DnaA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024633">
        <property type="entry name" value="DnaA_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038454">
        <property type="entry name" value="DnaA_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010921">
        <property type="entry name" value="Trp_repressor/repl_initiator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30050:SF2">
        <property type="entry name" value="PTHR30050:SF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00308">
        <property type="entry name" value="Bac_DnaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08299">
        <property type="entry name" value="Bac_DnaA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11638">
        <property type="entry name" value="DnaA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00051">
        <property type="entry name" value="DNAA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00760">
        <property type="entry name" value="Bac_DnaA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48295">
        <property type="entry name" value="SSF48295"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00362">
        <property type="entry name" value="DnaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01008">
        <property type="entry name" value="DNAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 9 10" id="KW-0235">DNA replication</keyword>
    <keyword evidence="8 9 10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6 9 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="12">
        <location>
            <begin position="158"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="domain" description="Bac_DnaA_C" evidence="13">
        <location>
            <begin position="369"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="166"/>
            <end position="173"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00377"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="PRC94036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="461" mass="52528" checksum="F2E79EBAE548D938" modified="2018-07-18" version="1">MENFWQACSAQLEQELTPQQFSAWIKPLTPLDYSEGKLRITAPNRFKLDWVKTQFASRITELAIQFWDDQIDVQFILDPRLNVARKPSHDLPATVDIGTSPDEVRSPEEVRPTTIIETPKRDQSRINNALTFDSFVTGKANQLARAAAIQVANNPGVSYNPLFLYGGVGLGKTHLIHAIGNQILIDNPNAKIRYIHAEQYVRDVVTAYQRKGFDEFKRYYHSLDLLLIDDIQFFAGKNRTQEEFFYAFEALIAAKKQIIITSDTYPKQITGMDDRLISRFDSGLTVAIEPPELEMRVAILLKKAKQEGVVFSDDVAFFVAKHLRSNVRELEGALRKILAYSRFHGKDITIDVVKEALKDLLSVQNRQISVENIQKTVADFFNMKVADMYSKRRPANIARPRQIAMYLAKELTQKSLPEIGELFGGRDHTTVLHAVRKITADRSKNPECNHELHVLEQTLKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2L2</accession>
    <name>A0A2S9H2L2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="10">TonB dependent receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">S2091_1356</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94183">
        <property type="protein sequence ID" value="PRC94183"/>
        <property type="gene ID" value="S2091_1356"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="3 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 10" id="KW-0675">Receptor</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0798">TonB box</keyword>
    <feature type="domain" description="Plug" evidence="9">
        <location>
            <begin position="53"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="8">
        <location>
            <begin position="353"/>
            <end position="887"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="83"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC94183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="888" mass="94924" checksum="F959E2564EC7273E" modified="2018-07-18" version="1">MIKEKNLSRSMRSIFSSGIALGMGVLGGSALAQEAEVVQRVEITGSSIKRMASETALPITIIKADTFVKQGLTTAEDVLNSLGSNQSSSGGSQSVGSGSGGKSSADLRGIGTNKTLILLNGRRLANHPYDGSSVDLNIIPVGALDRVEVLRDGASAIYGTDAIGGVINFITKRSVKGVEVTGEGVNPQHKGGGEARFNLLAGIGDLEEDGFNVFGVFDWHKQNALKATDRDFSATGIIPNRGLNKMSGNTGSANFYDPISGLSGNMSRAAGCNPAQNSYIKNATSCGYDYTADIDDIPQTEQWSFLGKASYKLNADNVLTLEYLHSDSTNIGRVAPTPFYTGSGSLPGLNIDSNSPFYPGNGITPAYPGLSGGPLDLNWRSMDAGQRREKDKSKTDRFLIGAEGLLAGWDYKTGFMYAQSKATTTLTNGYLKDSGVLAGITGGIINPFGPQNAAGLAYLDSIALNGELYSGTTKRTGIDFTASREFGRLAGGAMGVAIGTEFAHESAAYTVNRSVADQASATGGSDAQNVSGARNISALFGEFTAPVTKELEVQLAARYDYYSDVGGTFNPKIGIRYQPAKELLLRASANTGFRAPTLFEKFSPDSTTNTANTYNDPALCPGGTALPGQNPSLVCNAQQQIRGGGSANLAPEKAKNFSVGFVYEPNSAMTFSADYWNLRITDSIGTLPETVIFGNPTKYADLFVRNPDGSLKYVLATNANLGGINTDGIDASMTLRLPKTSLGNFVVNLDGTYVNQYKYQNEKDGAWTQNVGTYADNSPVFRWKHTLSLMWTKNVWSTTLSQQFMTGYHDQNQQVAAQYYQDVSSYSIWNLTGTYSGFKNVTLTAGLKNLFDKNPPFTNQGTTFQQGYDPRFTNPVGRALYLRGTYRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2Q6</accession>
    <name>A0A2S9H2Q6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Bacterial extracellular solute-binding protein, family 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_0844</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94223">
        <property type="protein sequence ID" value="PRC94223"/>
        <property type="gene ID" value="S2091_0844"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001638">
        <property type="entry name" value="Solute-binding_3/MltF_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00497">
        <property type="entry name" value="SBP_bac_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015461030" evidence="2">
        <location>
            <begin position="21"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="domain" description="PBPb" evidence="3">
        <location>
            <begin position="35"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC94223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="241" mass="26799" checksum="5806D5FCB4B6CBE3" modified="2018-07-18" version="1">MRNKQLLVLLPVLFCAQVLAAQPAIVFAASTDNAMPLAEFHNNALDSGILKELGEAIGHELHLATLFISLPRNRLEAALISGEVDGACYIRPEWVEAQLNWSQPLIPNENLLATNPTLPQTMALKDVSGKTLGLVVGYKYPELDAALGSNYRRDDAPDMLHVIKKLLIGRELYAVVDRLSFEYQITKYPQLKQFSTLTISTFHTPCGFSLASKIPFTEIDNAINKLILDGTIDHILTRYRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2S3</accession>
    <name>A0A2S9H2S3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0903</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94282">
        <property type="protein sequence ID" value="PRC94282"/>
        <property type="gene ID" value="S2091_0903"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-binding" evidence="1">
        <location>
            <begin position="14"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding_C" evidence="2">
        <location>
            <begin position="415"/>
            <end position="491"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="520" mass="57241" checksum="69FDDB048E1DDA95" modified="2018-07-18" version="1">MTNINLAAHFIVSKRKSDALCFVGPDISLSYRQLDCAVRCQAHWLEQQGVRADQRIAIGLDDGAELAVLFFAALALGALPLLINPRLDAPAMRHIFDDSDPVIVFGQHEQKTVLTEVIASAAHPTHLRLIKAGMHRDWITPTAEGSAWNGFLMRPLTAPAFIQYTSGTTGQAKGVLHSAASIISSCAGFAAGQLRINSSDLLYSVPKAFFGYGMGNSLFFPLYLGACALLDPAWPTAELVAANLKRYRPNVLFAVPTMYRLLLEEGLQPSNCSLRLAFSAGAPLAECISAMWQQRFGFDLHDGIGATELCHVFATTYPDRLRRGSVGRMLDGWQARIVDEQGALAADDEPGVLLVKAPSMALCYWRRPQDDALKFVDGWYRTGDLFTTDSDGFLYFHGREDERFKVFGRWVMPSEVESLLSQHAGVLGECYLVPGRDATGEDRPVLYIRANDDFEQQARFALATLKTHLESFKYPAKVLPLETLPMTANGKLNRRALASQASNALQAVMPTQHEESDLLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2Y8</accession>
    <name>A0A2S9H2Y8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0951</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94330">
        <property type="protein sequence ID" value="PRC94330"/>
        <property type="gene ID" value="S2091_0951"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009387">
        <property type="entry name" value="HigB-2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039032">
        <property type="entry name" value="HigB-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="89" mass="10119" checksum="718213E5CF6F5A47" modified="2018-07-18" version="1">MRDTEREEFIDWIADNPLAGDVISGSGGLRKVRWSRSGMGKSGGARVIYYTRLASGELVLLLVYAKAKFDNLRPEFLLKLKEHFDEQTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H331</accession>
    <name>A0A2S9H331_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 9">2-dehydropantoate 2-reductase</fullName>
            <ecNumber evidence="4 9">1.1.1.169</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8 9">Ketopantoate reductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">S2091_1002</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>(R)-pantoate + NADP(+) = 2-dehydropantoate + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:16233"/>
            <dbReference type="ChEBI" id="CHEBI:11561"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15980"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.169"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 9">Cofactor biosynthesis; (R)-pantothenate biosynthesis; (R)-pantoate from 3-methyl-2-oxobutanoate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the ketopantoate reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.169" evidence="4 9"/>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94381">
        <property type="protein sequence ID" value="PRC94381"/>
        <property type="gene ID" value="S2091_1002"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00028">
        <property type="reaction ID" value="UER00004"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008677">
        <property type="term" value="F:2-dehydropantoate 2-reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015940">
        <property type="term" value="P:pantothenate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003710">
        <property type="entry name" value="ApbA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013752">
        <property type="entry name" value="KPA_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013332">
        <property type="entry name" value="KPR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02558">
        <property type="entry name" value="ApbA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08546">
        <property type="entry name" value="ApbA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00745">
        <property type="entry name" value="apbA_panE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0520">NAD</keyword>
    <keyword evidence="9" id="KW-0521">NADP</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6 9" id="KW-0566">Pantothenate biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ApbA" evidence="10">
        <location>
            <begin position="3"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="domain" description="ApbA_C" evidence="11">
        <location>
            <begin position="178"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00019465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00032024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU362068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF08546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PRC94381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="307" mass="32420" checksum="755C342F1C9B11B7" modified="2018-07-18" version="1">MRILILGVGGTGGYYGARLAAAGCDVTFLLRPGSAQRIARDGLKLTSVRGDVHMPVQVVTQVEQPADLVILSCKSYDLEAAIAAITPAVGAHTLVLPLLNGLRHLERLNQAFGRGRVLGGMCNISVGRSADGAIEHYNRYDELRFGAQPEAKAPGPIDASAVAEVFKSAHFLSVLSSDIEQDMWEKFVFITTLAGMTCALRSDIGGIVATAPGDQLMRDALAECQAVAAANGHAVRPLAHKLAMRAFTEKGSTFAASMLRDLQAGHCTEAEHIVGDMAQCAAAAGLPHPCLRMALCHLQVYEHALAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3J6</accession>
    <name>A0A2S9H3J6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Methyl-accepting chemotaxis protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_0543</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyl-accepting chemotaxis (MCP) protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94540">
        <property type="protein sequence ID" value="PRC94540"/>
        <property type="gene ID" value="S2091_0543"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024478">
        <property type="entry name" value="HlyB_4HB_MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004089">
        <property type="entry name" value="MCPsignal_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12729">
        <property type="entry name" value="4HB_MCP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00015">
        <property type="entry name" value="MCPsignal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00283">
        <property type="entry name" value="MA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50111">
        <property type="entry name" value="CHEMOTAXIS_TRANSDUC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0807">Transducer</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="6">
        <location>
            <begin position="212"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="domain" description="Methyl-accepting transducer" evidence="5">
        <location>
            <begin position="269"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="469"/>
            <end position="507"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00029447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC94540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="517" mass="54825" checksum="3FE8B720A9A67360" modified="2018-07-18" version="1">MGNVTMKVSTRLNVGFGVVLLMMVIIIVIALSRFSDIGTTIDRIIEKDWAKAENANIVNVTARDNARRTLELLIATDKTQIDSIHTHIEANKKTVGDALNALEKLIYIPEGKILLVKIKEARSNYVSSFSKVGKLIDEGKKEEAIHLMNTETLPNLDTFQDLIAALSDIQKKAAITGGEEVKHDIGSATILMTCLGIAATLLGIAGAFVITRSISTPLIAALNIAKTVAAGDLRSRFEVNSNDEIGQLLQALKEMNANLVSIVGEVRIGTDTIVTASSQIASGNLDLSSRTEAQASALEETASSMEELTSTVKQNADNANQAKQLAYSASEVAVRGGAVVMKVVDTMGSINESSKKIVDIISVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVASEVRNLAQRSAAAAKEIKTLIGDSVEKVDIGAKLVDQAGTTMNEVVASVKRVTDIINEITSAGNEQSAGIEQINQAIIQMDNVTQQNAALVEEAAAAAQSMQDQSKKLSEVVSVFKLEAGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3U2</accession>
    <name>A0A2S9H3U2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0652</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94649">
        <property type="protein sequence ID" value="PRC94649"/>
        <property type="gene ID" value="S2091_0652"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NADP_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="SSF51430"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldo_ket_red" evidence="1">
        <location>
            <begin position="17"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="296" mass="32680" checksum="55927A69EBB7682A" modified="2018-07-18" version="1">MPNTRIHLSANGPEFSRIALGLWRLDSWQLSTAKRLDFLQQAIALGITTIDHADIYGSEAPFGEALALAPSLRTKIEIITKCGIVWRDEKSLLRVTHYDTSRAHIIASLENSLRLLGTDYVDLLLIHRPDPLMQADEIAEAFQLLQRAGKVRHFGVSNFTPAQFDLLASRHKLTTNQIELSPLHLDSLHDGTLDQCQRLSISPIIWSALGGGRVFNEHSPRAERLRVTLAALGAEYGVSATTIVYAWLLQHPSKPVVLTGSGRVFALREAVAAIGLTLTREHWFAVWCASTGTAVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3Y0</accession>
    <name>A0A2S9H3Y0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alpha/beta hydrolase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0680</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94677">
        <property type="protein sequence ID" value="PRC94677"/>
        <property type="gene ID" value="S2091_0680"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022742">
        <property type="entry name" value="Hydrolase_4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12146">
        <property type="entry name" value="Hydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015727833" evidence="1">
        <location>
            <begin position="24"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="domain" description="Hydrolase_4" evidence="2">
        <location>
            <begin position="213"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="486" mass="52298" checksum="4D27390A599737C0" modified="2018-07-18" version="1">MQPYLKNTLILVALLALPPLTQAETETGTEIQAAAKTEISAETPASLLKDHKGYWLGDLKIPNGPTLKIGAELFTRADGSYWASVSSPDQDAYDIPVKSIHGTGDALELDFSFAAMKLTWVNDHFMGDYKQGDFAQSMEMKQVSEFPMKVRAQTPKAPFPYKDETLAISSTDGVTLGATLSIPNGKTHPNVVILVSGSGPNNRDEDAAGHQPFAVLADYLARQGVAVLRYDKRGVGRSTGDYEQHTTAQLIDDLNAVVQALKARKEFNHLGLIGHSEGPGIAAAVAAHQPKSVDFVISLAGVGLPGLDMMLLQDHIWAKDHGASPAEEERILTIYVQKFYETIIAQADVEPRIVALKALYSGLAPEDQALVKKLKMNMGSLSLAQAKQPGLRTLLMSNPALDWRMVRCPVLALNGSLDHQVPVESLAGIVAALKAGGNPKVESAILPSLNHLFQTAKTGGEEEYDKIDETIAPGALQKIAAFSIQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H415</accession>
    <name>A0A2S9H415_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0676</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94673">
        <property type="protein sequence ID" value="PRC94673"/>
        <property type="gene ID" value="S2091_0676"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="80" mass="7937" checksum="A8E1938F3C7553E3" modified="2018-07-18" version="1">MIGGAFEFTVAVTVAVAVAVAVAVAVAVAVAVAVAVAVAVAVAVAVAVAVAVDFEFAFDLPPLLVRPVFPRKKGSERFAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H424</accession>
    <name>A0A2S9H424_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0738</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94735">
        <property type="protein sequence ID" value="PRC94735"/>
        <property type="gene ID" value="S2091_0738"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041492">
        <property type="entry name" value="HAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13419">
        <property type="entry name" value="HAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01549">
        <property type="entry name" value="HAD-SF-IA-v1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="196" mass="21226" checksum="632E232A23CDD9F3" modified="2018-07-18" version="1">MAISVVVFDAFGTLVQIGERRSPYRKLMQWMRANGRRPQTSDAGRIMSQPGGLADVANLFDLSPPVDLLAAWEAELHAELATVKLFPDSLPTIARLRNAGYRIGLCSNLAAPYGTPVKALLPSLDAYAWSYEAGAVKPEPGIYRYLLDRLGCAASDVLFIGDTPAADLDGPLTFGMSARLIDRKAGQTLDKVLDDM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4U3</accession>
    <name>A0A2S9H4U3_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Alanine--tRNA ligase</fullName>
            <ecNumber evidence="11">6.1.1.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Alanyl-tRNA synthetase</fullName>
            <shortName evidence="11">AlaRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">alaS</name>
        <name evidence="14" type="ORF">S2091_0197</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>ATP + L-alanine + tRNA(Ala) = AMP + diphosphate + L-alanyl-tRNA(Ala)</text>
            <dbReference type="Rhea" id="RHEA:12540"/>
            <dbReference type="Rhea" id="RHEA-COMP:9657"/>
            <dbReference type="Rhea" id="RHEA-COMP:9923"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78497"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="11">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="11">Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 11">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.7" evidence="11"/>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95002">
        <property type="protein sequence ID" value="PRC95002"/>
        <property type="gene ID" value="S2091_0197"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004813">
        <property type="term" value="F:alanine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006419">
        <property type="term" value="P:alanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00036_B">
        <property type="entry name" value="Ala_tRNA_synth_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002318">
        <property type="entry name" value="Ala-tRNA-lgiase_IIc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018162">
        <property type="entry name" value="Ala-tRNA-ligase_IIc_anticod-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018165">
        <property type="entry name" value="Ala-tRNA-synth_IIc_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018164">
        <property type="entry name" value="Ala-tRNA-synth_IIc_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023033">
        <property type="entry name" value="Ala_tRNA_ligase_euk/bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003156">
        <property type="entry name" value="DHHA1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018163">
        <property type="entry name" value="Thr/Ala-tRNA-synth_IIc_edit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012947">
        <property type="entry name" value="tRNA_SAD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02272">
        <property type="entry name" value="DHHA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01411">
        <property type="entry name" value="tRNA-synt_2c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07973">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00980">
        <property type="entry name" value="TRNASYNTHALA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00863">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101353">
        <property type="entry name" value="SSF101353"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55186">
        <property type="entry name" value="SSF55186"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00344">
        <property type="entry name" value="alaS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50860">
        <property type="entry name" value="AA_TRNA_LIGASE_II_ALA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 11" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="7 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 11 14" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9 11" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 11" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 11" id="KW-0820">tRNA-binding</keyword>
    <keyword evidence="6 11" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II_ALA" evidence="13">
        <location>
            <begin position="1"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="726"/>
            <end position="753"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="559"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="563"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="660"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="664"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="PRC95002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="869" mass="94332" checksum="EDB511A2C64843F7" modified="2018-07-18" version="1">MKSSEIREKFLKFFESKGHSIVRSSSLIPGTDPTLLFTNSGMVQFKDVFLGQDQRSYTRATTAQRCVRAGGKHNDLENVGYTARHHTFFEMLGNFSFGDYFKRDAIHYAWELLTVVYGLPKDKLTITVYQTDEEAYGIWLNEIGVPAERIIRIGDNKGAPYASDNFWQMADTGPCGPCSEIFYDHGPEIWGGPPGSEQEDGDRFIEIWNLVFMQYNKDEQGVLHPLPKPCVDTGMGLERLAAVLQHVHSNYEIDAFQALIKAAARETACSDLDHNSLKVIADHIRCAAFLIVDGIIPGNEGRGYVLRRITRRALRHGHKLGQTKPFFYKLVADLVGEMGVAYPELAQVAERVAQVLQQEEERFGETLEHGMKILEAALAKDSQRLDGRTAFTLYDTYGFPLDLTADICRERNVELDQAGFDTAMEHQKQTARAAGKFKMSAGIEYSGAKTNFVGYEKLAQASKVIALYVDGSPVQQISAGQSALVVLDTTPFYAESGGQCGDRGGLSAPGISFEVSDTTKIQPDVFGHHGELVTGTLAVGQSVEAHVAEAVRAQTVRNHSATHLMHKALREVLGAHVAQKGSLVDADKTRFDFSHNAAMTFDEIRQVEEIVNCEILTNSAAQAQVMAFDDAVKHGAMALFGEKYGDEVRVLDIGSSRELCGGTHVKRTGDIGFFKIVSEGGIAAGIRRVEAVTGEVAVHLVQNLTARLGEAAALLKTQPDDLLHRIVLVQEQVKSLEKEMTQLKSKLAANQGNELASQAVDIKGIKVLAVVLEGADANTLREVTEKLKNSLKTAAIVLASVQDGKVSLVAGVTADTTARVKAGDLVNFVALQVGGKGGGRPDMAQAGGTNPAGLAQALAGVAAWVTERA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4X7</accession>
    <name>A0A2S9H4X7_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5 6">50S ribosomal protein L19</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rplS</name>
        <name evidence="8" type="ORF">S2091_0186</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 6">This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the bacterial ribosomal protein bL19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94991">
        <property type="protein sequence ID" value="PRC94991"/>
        <property type="gene ID" value="S2091_0186"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00402">
        <property type="entry name" value="Ribosomal_L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038657">
        <property type="entry name" value="L19_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001857">
        <property type="entry name" value="Ribosomal_L19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018257">
        <property type="entry name" value="Ribosomal_L19_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15680">
        <property type="entry name" value="PTHR15680"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01245">
        <property type="entry name" value="Ribosomal_L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002191">
        <property type="entry name" value="Ribosomal_L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00061">
        <property type="entry name" value="RIBOSOMALL19"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="SSF50104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01024">
        <property type="entry name" value="rplS_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01015">
        <property type="entry name" value="RIBOSOMAL_L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 8" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="108"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00402"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC94991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="128" mass="14471" checksum="DD146600F0727699" modified="2018-07-18" version="1">MDLIQQLEQEEIARLGKNIPDFAPGDTVIVYVNVVEGTRKRAQAYEGVVISRRRRGLNSNFIVRKISSGEGVERTFQLYSPLIASIEVKRRGDVRRAKLYYLRERSGKSARIKEKLPARKVKSAPAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4X8</accession>
    <name>A0A2S9H4X8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">EAL domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0178</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94983">
        <property type="protein sequence ID" value="PRC94983"/>
        <property type="gene ID" value="S2091_0178"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001633">
        <property type="entry name" value="EAL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035919">
        <property type="entry name" value="EAL_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00563">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141868">
        <property type="entry name" value="SSF141868"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EAL" evidence="1">
        <location>
            <begin position="39"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="292" mass="33343" checksum="03CBF3DAA2055B6B" modified="2018-07-18" version="1">MAYQALQKYITHLYTTKSNNTNIWINDTGQAQGRYFNSSLTSAFQALRSTLDLQIVGYQGLARSYTPGQQTELGLSLWRLLDHAASDDESIELDRLCRLLHAINFYRQPQAFGQDIYLNVHSRLLAAIQNNHGAAFRRILDTLELPHQHIVLELPLSAQNQRWILNHVSDNYRSNGFRIAVNINSIEQGLELEELIKQRHFAALKLDSSACHERSNLAALAKLLKTAQKHSTNVIIKRLDNDQQYRAIEQLAHETKQEIYVQGFLFDQPSSSLFSAPVKQRDKIECKKCQAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4Z6</accession>
    <name>A0A2S9H4Z6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putative threonine efflux protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_0206</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95011">
        <property type="protein sequence ID" value="PRC95011"/>
        <property type="gene ID" value="S2091_0206"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001123">
        <property type="entry name" value="LeuE-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30086">
        <property type="entry name" value="PTHR30086"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01810">
        <property type="entry name" value="LysE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="40"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="71"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="129"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="154"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="185"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC95011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="211" mass="22934" checksum="D2B054B7CC0568D9" modified="2018-07-18" version="1">MFGIENFLAFLLAATLIIIIPGPATFFVMGKAHLTFAHAVFAALGIIIGDVALITVSGLGFSSLIARFPLLLMSVKIGGALYVLYLGLALLKSGSKNELRNSLTKPAQGQRFQAFVRGILITLTNPKPILFFSTFFPMFIMAGTKSVVKSFYLLGMYFEILNLSYFCILLLIVTQLQQLSSYNRFIGGGFKSVSGVGLLCCGTFILVTSFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H561</accession>
    <name>A0A2S9H561_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">YhhN-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_0303</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TMEM86 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95108">
        <property type="protein sequence ID" value="PRC95108"/>
        <property type="gene ID" value="S2091_0303"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012506">
        <property type="entry name" value="YhhN"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07947">
        <property type="entry name" value="YhhN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="42"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="68"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="97"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="131"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="158"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="187"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="224"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC95108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="250" mass="27811" checksum="8DA785D5C6825816" modified="2018-07-18" version="1">MKQQSMSKCVPNKITIVLNLLFLLDAIWQIWALATHHTDQTLISKFLLCFILALLLSQQLANKLPLKILAAVLFCLAGDILLQPLDLNYADMTGTRPINFVLGVLCFCAAYGNLARYYLALNPDWREDIKAQPLPLVANILITLAVLIWITLNNQAPAYLLLVLWLYSPIVVGAATLAVYTRSKLQFLPYLALVLGSNVIVFSDTIIGLTAFVGVTMPWFSNPIWILSTYILGIFLVFNAILCIEKTANV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H566</accession>
    <name>A0A2S9H566_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CENP-V/GFA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_0327</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Gfa family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95132">
        <property type="protein sequence ID" value="PRC95132"/>
        <property type="gene ID" value="S2091_0327"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016846">
        <property type="term" value="F:carbon-sulfur lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006913">
        <property type="entry name" value="CENP-V/GFA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011057">
        <property type="entry name" value="Mss4-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51316">
        <property type="entry name" value="SSF51316"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51891">
        <property type="entry name" value="CENP_V_GFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CENP-V/GFA" evidence="3">
        <location>
            <begin position="11"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC95132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="128" mass="14328" checksum="B26282D3861FF186" modified="2018-07-18" version="1">MAEEMLNTLTLQGSCHCGAVTLTLPSMPETATKCNCSLCRRLGVLCAYYPFGTVRIEGHPEHTVDYVWGDKSLRTVRCKICGCATHWEPIDGELGSRHGVNLNNFDPRLQELVKVRHFDGADTWTFID</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H575</accession>
    <name>A0A2S9H575_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Polysaccharide deacetylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0335</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95140">
        <property type="protein sequence ID" value="PRC95140"/>
        <property type="gene ID" value="S2091_0335"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002509">
        <property type="entry name" value="NODB_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01522">
        <property type="entry name" value="Polysacc_deac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="SSF88713"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51677">
        <property type="entry name" value="NODB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015705267" evidence="1">
        <location>
            <begin position="43"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="domain" description="NodB homology" evidence="2">
        <location>
            <begin position="61"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC95140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="315" mass="35398" checksum="BE53209453202600" modified="2018-07-18" version="1">MLIQFRTFTFRKLLCPPPYQLCFTKFLFFLTITCCFSTACLANPASAELAESAAPATPAPIRFLLSFDDGPSGNKYNNSTEQVLEVLANNHVQAGIKALFFTQTRAVTGGGTAIGRKLMQREWNEGHLLGFHTATPHHSNHRFLSEPEFEQSLQDGIADLTEITGVAPKLVRPPFWNYDKRTFAAYQRHGMQVLLTDLSANDGKIWGVNFSFHKHSNMLKQLGELRAKWLAGKLPVVDGCTPIVVTFHDVNTYTSNHVEVYLEILVQVAAELEMPTTTIPFYTNRDELERAALTSAMHDTSIKPPLPGIWNWLWQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5E5</accession>
    <name>A0A2S9H5E5_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase</fullName>
            <ecNumber evidence="7">6.3.2.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Meso-A2pm-adding enzyme</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Meso-diaminopimelate-adding enzyme</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">UDP-MurNAc-L-Ala-D-Glu:meso-diaminopimelate ligase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">UDP-MurNAc-tripeptide synthetase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">UDP-N-acetylmuramyl-tripeptide synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">murE</name>
        <name evidence="12" type="ORF">S2091_0404</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>ATP + meso-2,6-diaminoheptanedioate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate = ADP + H(+) + phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptanedioate</text>
            <dbReference type="Rhea" id="RHEA:23676"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57791"/>
            <dbReference type="ChEBI" id="CHEBI:83900"/>
            <dbReference type="ChEBI" id="CHEBI:83905"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.13"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="7 8">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7 8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="7">Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the MurCDEF family. MurE subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.13" evidence="7"/>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95209">
        <property type="protein sequence ID" value="PRC95209"/>
        <property type="gene ID" value="S2091_0404"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008765">
        <property type="term" value="F:UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00208">
        <property type="entry name" value="MurE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036565">
        <property type="entry name" value="Mur-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004101">
        <property type="entry name" value="Mur_ligase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036615">
        <property type="entry name" value="Mur_ligase_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013221">
        <property type="entry name" value="Mur_ligase_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000713">
        <property type="entry name" value="Mur_ligase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035911">
        <property type="entry name" value="MurE/MurF_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005761">
        <property type="entry name" value="UDP-N-AcMur-Glu-dNH2Pim_ligase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01225">
        <property type="entry name" value="Mur_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02875">
        <property type="entry name" value="Mur_ligase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08245">
        <property type="entry name" value="Mur_ligase_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53244">
        <property type="entry name" value="SSF53244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53623">
        <property type="entry name" value="SSF53623"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63418">
        <property type="entry name" value="SSF63418"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01085">
        <property type="entry name" value="murE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7 8" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2 7 8" id="KW-0132">Cell division</keyword>
    <keyword evidence="3 7 8" id="KW-0133">Cell shape</keyword>
    <keyword evidence="6 7 8" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0436">Ligase</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 7 8" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mur_ligase" evidence="9">
        <location>
            <begin position="31"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="domain" description="Mur_ligase_M" evidence="11">
        <location>
            <begin position="114"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="domain" description="Mur_ligase_C" evidence="10">
        <location>
            <begin position="352"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="region of interest" description="UDP-MurNAc-L-Ala-D-Glu binding" evidence="7">
        <location>
            <begin position="163"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Meso-diaminopimelate binding" evidence="7">
        <location>
            <begin position="429"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Meso-diaminopimelate recognition motif" evidence="7">
        <location>
            <begin position="429"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="33"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:83900"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="116"/>
            <end position="122"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="190"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:83900"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="196"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:83900"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="198"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:83900"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="406"/>
        </location>
        <ligand>
            <name>meso-2,6-diaminoheptanedioate</name>
            <dbReference type="ChEBI" id="CHEBI:57791"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="482"/>
        </location>
        <ligand>
            <name>meso-2,6-diaminoheptanedioate</name>
            <dbReference type="ChEBI" id="CHEBI:57791"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="486"/>
        </location>
        <ligand>
            <name>meso-2,6-diaminoheptanedioate</name>
            <dbReference type="ChEBI" id="CHEBI:57791"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-carboxylysine" evidence="7">
        <location>
            <position position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF08245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PRC95209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="522" mass="56498" checksum="2752054A9FAEC863" modified="2018-07-18" version="1">MDNFQKTIPVVMNTVQWLQNLAPATTLNLVSDSRKVQVGDVFFAYPVGNADGRNYIQQAIAQGACAVVYEELNFTWDAKWNLPHFAVANLLWQSGFIASSYLNQPDATLFTVAVTGTNGKTSCTQWLARAMSLLGTPTCVVGTLGVGLVKNGRAGEFDVTGFTTPDAIQLQQKIATQRDLGAAAIAIEASSIGLEQGRMNGMHVDVAVLTNFTRDHLDFHGDMASYEAAKTKLFEWSNLTAAVLNFDDAAGLRLLQLCKTRGTQVLGYTVESTVDAAIDFGEQVSVLRASNLRNYHGGTSFHLDSPFGSGVIKTQMIGRFNVSNVLAVLATLFAKGIAWRDAVHAIEQLTSVAGRMEQLSAPGRVLVIIDYAHTPDALEKTLLNLKEVAQQRQGKLWCVFGCGGDRDPGKRPEMGKIAELADEIIATSDNPRNEEPEHILSQIAAGFTANRTPVPMMEPDRAKAILYAIKHADKNDVVLLAGKGHEAYQEIKGKKLPFSDIDHAHIALADLATKFVNKGGAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5J8</accession>
    <name>A0A2S9H5J8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative integral membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0423</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95228">
        <property type="protein sequence ID" value="PRC95228"/>
        <property type="gene ID" value="S2091_0423"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018740">
        <property type="entry name" value="DUF2282_membr"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10048">
        <property type="entry name" value="DUF2282"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015473943" evidence="2">
        <location>
            <begin position="24"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC95228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="92" mass="9061" checksum="8E2F038B03F26448" modified="2018-07-18" version="1">MTKNNALIAVALAGLMSSGFAAAADATAGGAKMEKCFGVAKAGQNDCASKAGGHSCAGQSKKDLSPNDWKNVPAGTCASMGGKVEEMKPAAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5U9</accession>
    <name>A0A2S9H5U9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="11">TonB family C-terminal domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">S2091_0451</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
            <orientation evidence="1">Periplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TonB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95256">
        <property type="protein sequence ID" value="PRC95256"/>
        <property type="gene ID" value="S2091_0451"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006260">
        <property type="entry name" value="TonB/TolA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037682">
        <property type="entry name" value="TonB_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03544">
        <property type="entry name" value="TonB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01352">
        <property type="entry name" value="tonB_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015629890" evidence="9">
        <location>
            <begin position="24"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_C" evidence="10">
        <location>
            <begin position="37"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF03544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC95256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="115" mass="12255" checksum="3D4221F58615CF7C" modified="2018-07-18" version="1">MKTRLSNIAALAATLYVCVAAFGAEVAPVLDSKSCDPPKYPKAALMNEETGTVSLLFLVAADGKVVDSKVEKSSGSKSLDKAALTAFSQCKFKPGTKDGKPDQLWAKVEFVWKLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GS75</accession>
    <name>A0A2S9GS75_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4728</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000056">
        <property type="protein sequence ID" value="PRC90561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90561">
        <property type="protein sequence ID" value="PRC90561"/>
        <property type="gene ID" value="S2091_4728"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="100"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="135"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="166"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="193" mass="22050" checksum="781A0216A15D4E9F" modified="2018-07-18" version="1">MFKSLSNRTKWILCLLLIILYGFGFREFWNVFLFDKLIGYSKEVKSIIFDIVFFIPMLVLILQSTKYTDKNTNENVKKKTVDETYGFKALWIGAMPLSRVFIFLFISTILVIFLGQVLFLNFASNGVGLIIRNSAFYIAIFGLYICSAVGAWRSSKKHIGNKLLPLVFNVGIILSFVLILTGLILSLIGFRIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GS94</accession>
    <name>A0A2S9GS94_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4725</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000055">
        <property type="protein sequence ID" value="PRC90566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90566">
        <property type="protein sequence ID" value="PRC90566"/>
        <property type="gene ID" value="S2091_4725"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015689954" evidence="1">
        <location>
            <begin position="24"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="153" mass="17320" checksum="95F2DF638B122EA5" modified="2018-07-18" version="1">MPSSILKLSVVFFMFIASSHLLAADISKDKKNILVNCHPTDCVDAIKDLDTNEQEQIIEIVKKIKFGLDETQISKYYPKIPNTSTPPKHEYGQQPNDVSHMASFYLVQQESLTSPIAGMTTSHMDVLFVNGGATLLKVWSNRMWHCVFIYLNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSG5</accession>
    <name>A0A2S9GSG5_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Fumarate hydratase class I</fullName>
            <ecNumber evidence="10">4.2.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">S2091_4636</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the reversible hydration of fumarate to (S)-malate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>(S)-malate = fumarate + H2O</text>
            <dbReference type="Rhea" id="RHEA:12460"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15589"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="EC" id="4.2.1.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 10">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="4 10">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the class-I fumarase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.2" evidence="10"/>
    <dbReference type="EMBL" id="PUGF01000040">
        <property type="protein sequence ID" value="PRC90653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90653">
        <property type="protein sequence ID" value="PRC90653"/>
        <property type="gene ID" value="S2091_4636"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004333">
        <property type="term" value="F:fumarate hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006091">
        <property type="term" value="P:generation of precursor metabolites and energy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004646">
        <property type="entry name" value="Fe-S_hydro-lyase_TtdA-typ_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004647">
        <property type="entry name" value="Fe-S_hydro-lyase_TtdB-typ_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036660">
        <property type="entry name" value="Fe-S_hydroAse_TtdB_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011167">
        <property type="entry name" value="Fe_dep_fumarate_hydratase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05681">
        <property type="entry name" value="Fumerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05683">
        <property type="entry name" value="Fumerase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001394">
        <property type="entry name" value="Fe_dep_fumar_hy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117457">
        <property type="entry name" value="SSF117457"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00722">
        <property type="entry name" value="ttdA_fumA_fumB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00723">
        <property type="entry name" value="ttdB_fumA_fumB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="7 10" id="KW-0408">Iron</keyword>
    <keyword evidence="8 10" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="9 10 13" id="KW-0456">Lyase</keyword>
    <keyword evidence="6 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fumerase" evidence="11">
        <location>
            <begin position="11"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="domain" description="Fumerase_C" evidence="12">
        <location>
            <begin position="289"/>
            <end position="489"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR001394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF05681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF05683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PRC90653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="506" mass="54521" checksum="3403DAB56F6E19C6" modified="2018-07-18" version="1">MTIIKQDDLIESVAAALQFISYFHPADYIQHLARAYEIEQSPAAKDAIAQILTNSRMCAEGKRPICQDTGIVNVFMKIGMGVRFEGFSGSIIDAVNQGVRQGYNNPENVLRASIVADPLFDRKNTKDNTPAVVHMELVPGDKLDIQVAAKGGGSENKSKFVMLNPSDSLIDWVMKTVPTMGAGWCPPGMLGIGIGGTAEKAMLMAKESLMEDIDMHELKLRGPQNKTEELRIALCDQINALGIGAQGLGGLTTVLDVKINMYPTHAASKPVAMIPNCAATRHAHFVMDGSGPVYMEPPALSSWPDVHWAPDTEKSQRVNLNTLTKAEVASWKPGQTLLLNGKMLTGRDAAHKRIQDMLAKGEQLPVDFTNRVIYYVGPVDPVRDEAVGPAGPTTATRMDGFTEMMLEQTGLISMIGKAERGPVAIESIKKHQSAYLMAVGGAAYLVSKAIKSAKVVGFADLGMEAIYEFDVIDMPVTVAVDSTGTSAHITGPKEWQAKIGLISTNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSQ8</accession>
    <name>A0A2S9GSQ8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ion channel</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_4502</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000036">
        <property type="protein sequence ID" value="PRC90754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90754">
        <property type="protein sequence ID" value="PRC90754"/>
        <property type="gene ID" value="S2091_4502"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013099">
        <property type="entry name" value="K_chnl_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07885">
        <property type="entry name" value="Ion_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="345"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="379"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="402"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="domain" description="Ion_trans_2" evidence="2">
        <location>
            <begin position="353"/>
            <end position="432"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC90754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="434" mass="48936" checksum="2F52393EF376FBCA" modified="2018-07-18" version="1">MSSLKISSRHWFVLEPLQVAHPIDAIYQKAAGFEIVGNWYLAGEAYIELHESLVGVSNKIVDSILIESKILARAASCFELAQDSRTSARFYERAAQKIVSSWLIPNPQLAAELYNRAALQYQASSEYFSAGATWNRAAEEFGNVKSNIITCTENRTPLPTSAFKSFLCGLCFEAAAIEFEKVAGNEMWSVGSYWRAGKAYEDGIPNIQAFNAYRRALNAHIRYYGTLDKDQMNNSLPLSQDERDLRIDPFDVMEKSLARCNNHHQLNPGVTPQSQLQTNRQMAEAFHGFNLELQSVGNAKEAANFRIEKSDRQRKILFAQHKYGISTRYLIWKLTSNYSESLGRWGITCFFVIMIFASLYSGFGLITTGVESIDKSFRFFDYIYFSVITFSTLGYGDLHPMGLFGQILACLEVICGLIMFGLLLSLVGSRLQRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSW7</accession>
    <name>A0A2S9GSW7_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Flagellar protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_4534</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Bacterial flagellum basal body</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the FliO/MopB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000036">
        <property type="protein sequence ID" value="PRC90786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90786">
        <property type="protein sequence ID" value="PRC90786"/>
        <property type="gene ID" value="S2091_4534"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009425">
        <property type="term" value="C:bacterial-type flagellum basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044781">
        <property type="term" value="P:bacterial-type flagellum organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022781">
        <property type="entry name" value="Flagellar_biosynth_FliO"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04347">
        <property type="entry name" value="FliO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03500">
        <property type="entry name" value="FliO_TIGR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0975">Bacterial flagellum</keyword>
    <keyword evidence="1 5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0966">Cell projection</keyword>
    <keyword evidence="7" id="KW-0969">Cilium</keyword>
    <keyword evidence="7" id="KW-0282">Flagellum</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015454809" description="Flagellar protein" evidence="6">
        <location>
            <begin position="19"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="37"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC90786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="147" mass="15737" checksum="7750BE84F84A13BF" modified="2018-07-18" version="1">MKLLTLFWLVVYCSASHAVDASAGSAAGSTTSLAAGNLIQVTLSLLLVIAILIALSVAFKKFGLNRIQAAFPVKVVGAISVGNHQRIMVIEAGDEWIVLGVTPQHISTITSMPRQKSDDTSNSNGNNKAHFSTWMQSALEKYHVKKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSY1</accession>
    <name>A0A2S9GSY1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4483</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000035">
        <property type="protein sequence ID" value="PRC90820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90820">
        <property type="protein sequence ID" value="PRC90820"/>
        <property type="gene ID" value="S2091_4483"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021738">
        <property type="entry name" value="DUF3309"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11752">
        <property type="entry name" value="DUF3309"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="28"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="50" mass="5458" checksum="774C04BDD161EF08" modified="2018-07-18" version="1">MSILLLIILIFILLGAFPTWPHSRNWGYAPSGISGLLLVVLIVLLITGQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GT84</accession>
    <name>A0A2S9GT84_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative permease DMT superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_4328</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000032">
        <property type="protein sequence ID" value="PRC90927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90927">
        <property type="protein sequence ID" value="PRC90927"/>
        <property type="gene ID" value="S2091_4328"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="74"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="102"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="133"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="158"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="191"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="225"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="258"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="281"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="18"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="156"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC90927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="302" mass="32145" checksum="A8F582F47A098C43" modified="2018-07-18" version="1">MNSTTQLSTTRLSPLVLLCLVATWFIWGSMYLAIKWALVSFPPFYQMGTQFIVAGILLAMFAKWRGANWPEPSQWVGGSILGALLLLGGYGFTALAETRVGSGLVVAFSAVVPSMVALAEWPYGARPGMRRGIGIVVGLIGIFLLTQGSGFSASTSGLLFMFIACVTWSIGSVWAVYGLPGGISLKIAPGFMGHASQMLIGGVMLLLVSFAVGEVPVWPPEPMALASWSYLMVAGSLVGYTAYMLLLERTSPTLASSYTYVNPIVALVLGTVLGGELVTSFEWVAVAVVLIGVILLMWKQRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTB8</accession>
    <name>A0A2S9GTB8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyl transferase family 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_4361</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000032">
        <property type="protein sequence ID" value="PRC90960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90960">
        <property type="protein sequence ID" value="PRC90960"/>
        <property type="gene ID" value="S2091_4361"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="2">
        <location>
            <begin position="24"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC90960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="322" mass="36028" checksum="4F1EC493A26F2B89" modified="2018-07-18" version="1">MNNLTNNPINNDDCVSNDETCDVSVIIPAFNAAETISRAVGSVLIQDVDSLEIIIVDDGSTDDTFIAVTELMQLHSVIRLLQMPKNGGVSAARNYGIREAKGKFLAFLDADDIWLAGKLKKQLVEIKRDPSITLVSCNSKLISESGEYLKEGHINRPPVEGAEAWKTLLIYNFLPTPTVLTHRHLVLELGGFDENLPVGEDLDLWIRLALRGKVIVLKEILINYYDSAGSLMKRHLAQTQMIVLPMLEKHLVQQKDKLSAKEIRHIRGLQSFQTGCNLFFADEYLPSIPAFLQAAYYGTRPMKSLTYVPRALLMLVFSLFNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTQ5</accession>
    <name>A0A2S9GTQ5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_4186</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000029">
        <property type="protein sequence ID" value="PRC91090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91090">
        <property type="protein sequence ID" value="PRC91090"/>
        <property type="gene ID" value="S2091_4186"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024534">
        <property type="entry name" value="DUF2220"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024537">
        <property type="entry name" value="DUF3322"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014544">
        <property type="entry name" value="UCP028408"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09983">
        <property type="entry name" value="DUF2220"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11795">
        <property type="entry name" value="DUF3322"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028408">
        <property type="entry name" value="UCP028408"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF3322" evidence="2">
        <location>
            <begin position="6"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="domain" description="DUF2220" evidence="1">
        <location>
            <begin position="209"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF11795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="394" mass="45341" checksum="F3B1C81951C9D0E8" modified="2018-07-18" version="1">MKWSTPDELRAQLQKRWERGELLASLLGSESPFPIRLTLKTPTSPDMAEHFDQVRTWIAALRAMPHCRIEMREFNHRLLGANAIPHQIWVDTLAAALVWLGKKRDAERFNTIIAITRAQQPQLLPWLAKRPLRALELAESWSLLLTIVGWLKAHPRPGIYLRQVDIPLVHSKLIEAHRALLSELFDLSLAPETIDFNATGVNQFAQRYGFLDKPHRIRFRLLDLISTRLPGAQLADITLDADSFARLNPAISRVFITENEINFLAFPLLPDSMVIFGAGYGFEMLSKAEWLSCCQMIYWGDIDTHGYAILDQLRNHFPHAQSFLMDRTTLMAFETQWGQEDKPMLRDLPRLTPDEAALFDDLRDNRIKKHLRLEQERIGFTWVEAALTILTSPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GU97</accession>
    <name>A0A2S9GU97_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3960</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000025">
        <property type="protein sequence ID" value="PRC91289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91289">
        <property type="protein sequence ID" value="PRC91289"/>
        <property type="gene ID" value="S2091_3960"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011712">
        <property type="entry name" value="Sig_transdc_His_kin_sub3_dim/P"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07730">
        <property type="entry name" value="HisKA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HATPase_c" evidence="1">
        <location>
            <begin position="386"/>
            <end position="480"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="498" mass="56683" checksum="3644A79A49A11441" modified="2018-07-18" version="1">MTMNQCGLLNKVIEGCFNEIYLIDAANSTYLEVSQIAQDKLGYAFEELQHMRPWQLARDFTQLEWQQQLEPLFTPGQQQKISISTYHTCKNGTQYPVLLNIMRDTSEGRDLLIVVGKDMSIQQRAITASAESDERCAAIVANLPGVVLQLLLNIDGTTRYMFLSANCESTLGVMPEILYISPSKFIEIILPEDRASYLTSMHESAQTQNHWNWEGRIWVEQWSDIKWIYLRAVPRMLEDLSVIWEAIITNITARKLIDVEIHLYRQRLTELSAHIERIKEQERMRIAREIHDEMGGNLVAVKMILHTLENRLPADQPWLTEKTHYVDTLIDRTIEAGHRIARDLRPSVLDLGLIPALDWQIKEFEKQYGIRCSFSTNKSDISLTPEHATAIFRMIQEALTNIAKHANATYASLAIIYTRTSISLTIADNGCGLETDHDSKPNSFGLLGMAERCKEIGGTILVDSQPNNGCVIAIKIPLIGQTRNPQFEEPMNDQLSLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUQ1</accession>
    <name>A0A2S9GUQ1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Vegetative insecticide protein 3A N terminal</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3855</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000023">
        <property type="protein sequence ID" value="PRC91440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91440">
        <property type="protein sequence ID" value="PRC91440"/>
        <property type="gene ID" value="S2091_3855"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022180">
        <property type="entry name" value="Vip3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12495">
        <property type="entry name" value="Vip3A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="550" mass="61219" checksum="631F8670AAC3D4BB" modified="2018-07-18" version="1">MKNMKKNKYNIAVRGLPVIDEFNGLVSFIGNLQSIFESIFDIGNTSSDPIDMGSIKDWMGSTSGQLGDVQQSIKELIESGELNTAHLKLLQSISLSQGLVLNEINSKLDSITGMLSIYLPKIVNMLSTINHQTTQILHVVNQIKAMMEVVLQRLDVINANVVINSSLIEVMPSIQRINFASDKFNALQGTFEESSKNTNASDNVNAMNEFISFCKNTTEPRIDNFEFYLDALHRGIIADNFLNRSVLNSFKDLLGASSNSSYTAVVYSFMTSLVASQISGYLALTACAKIMGFDISKNEQFLNDRIQEQRKFYLDNVLDNIETKVVHGSMVDYTMDPVNLQPTVAFDIVADDSYVILAIDFSIERGIQNQELVAFYQGKMTSNYQIEPGSIERVVIPTKGAATYIAFAGRDGITAAMAPRENCYLTGIHVDSTGKGYLEFKSYDFATGELSNEIEKVDFKETNDDGVMTLTDDKPWTFRQTDGVLSDMFLSPITGMGLASHPHASLDHVYLRDIYIKTDLNKLIRAVESTDDKDAALYYLKPEEDVILRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUQ8</accession>
    <name>A0A2S9GUQ8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3859</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000023">
        <property type="protein sequence ID" value="PRC91444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91444">
        <property type="protein sequence ID" value="PRC91444"/>
        <property type="gene ID" value="S2091_3859"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008962">
        <property type="entry name" value="PapD-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49354">
        <property type="entry name" value="SSF49354"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015609413" evidence="1">
        <location>
            <begin position="18"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="217" mass="24208" checksum="FF87B1BB1E47A13D" modified="2018-07-18" version="1">MYKKVIALLLLSSSASAWSITVGEMTYFMGSNQTYLSKAVLNDSTQARYYQVTVEETDPPYKGAKLHKVVKGALLYAPKQLLLRPNETKFLKLYYQGPSDDQPRYYRVTFHERPGFSMHSVSEAYFSGTASLSTILVVQPRQPKQSYQLSNGVLRNNGNTVYLAYAQAPCSDEAEKCVKEKYLIPGGELVLDTLSAQSGTLFLSNETMQEIPMTGTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUX4</accession>
    <name>A0A2S9GUX4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Helix-turn-helix domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_3797</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000022">
        <property type="protein sequence ID" value="PRC91519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91519">
        <property type="protein sequence ID" value="PRC91519"/>
        <property type="gene ID" value="S2091_3797"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018062">
        <property type="entry name" value="HTH_AraC-typ_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020449">
        <property type="entry name" value="Tscrpt_reg_HTH_AraC-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00032">
        <property type="entry name" value="HTHARAC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00041">
        <property type="entry name" value="HTH_ARAC_FAMILY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="4">
        <location>
            <begin position="162"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC91519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="274" mass="30234" checksum="74B1D14B0C67D473" modified="2018-07-18" version="1">MYVVNHTNAHSSCLAPTVERPVRVVGRDLTSNATLAAHSHLWGQLTYALQGAIRVTVGRYTWIVPPLRAIWIPANVEHAVTTLEAVRLRPLHVLSDIAPFQDQANIAECIVLDVSNLLRELMLALAELNLASEREDLLTKLILSEIKQATQLPLRITLPRDKRLIRLCNSIIANPGNKLTLADWATQAGASERTLARLFEQDCGMGFGVWRQQVRLAHSSHLVARGLPLSQVALELGYSSQAAFSSMFKKTFGVTPSVFFNSAGTNVTNLNRKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GV29</accession>
    <name>A0A2S9GV29_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Long-chain acyl-CoA synthetases (AMP-forming)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3677</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000021">
        <property type="protein sequence ID" value="PRC91561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91561">
        <property type="protein sequence ID" value="PRC91561"/>
        <property type="gene ID" value="S2091_3677"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-binding" evidence="1">
        <location>
            <begin position="23"/>
            <end position="479"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="609" mass="66657" checksum="DB43BB4E388063CC" modified="2018-07-18" version="1">MLKQTMSTDDNALSSINTLAELFAWRVRQTPTAEAYREFDNSSGQWISSSWQETNQHIAGFINALSTLAMARGSRIAILLPNGLHAVCIDQATLALAHVPVPMHALDNPASIAYILSDSDASFLIAATDEQWQSIAATNIAFPSLQQVVVLQKTQPESNSSVPVLNLQEWLATAHNTQEQSTAQFPEPHDLAALVYTSGTTGKPKGVMLTHQNVMSNVRAVVQRIAPVTDDVFLSFLPLSHTFERTAGYYLPIAAGACVVFSRSVKQLPEELLLVRPTILISVPRIYERVYAVIQSKLASSKAQNWLFNVAIAVGWRRFAGTQGMSSVNVLRSTLDELSWQILNPLVASKLMNQFGGRLRVAVSGGAALSPAISHCFLALGIPIVQGYGMTETAPIIAFNAPDDNDPATVGRPITGVEVKIGDNAELLVRGPNVMRGYWKREEDTAKTIIDGWLHTGDQAEIVADRVRIKGRVKEIIVTSTGEKIAPVDLELAITNDSAFEQAYAFGDNAPFIACAVVLSLSYWQQLAISLSLNPDDKQSLQSDSAVNAVVKRLRDLTQSFPYYAQPKAAILTLEPWTIENTLITPTLKLKRKNLEGHFAQDIQRIYSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GV88</accession>
    <name>A0A2S9GV88_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Polyhydroxyalkanoate synthesis repressor PhaR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3575</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000020">
        <property type="protein sequence ID" value="PRC91637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91637">
        <property type="protein sequence ID" value="PRC91637"/>
        <property type="gene ID" value="S2091_3575"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012909">
        <property type="entry name" value="PHA_DNA-bd_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010134">
        <property type="entry name" value="PHA_reg_PhaR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007897">
        <property type="entry name" value="PHB_accumulat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05233">
        <property type="entry name" value="PHB_acc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07879">
        <property type="entry name" value="PHB_acc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01848">
        <property type="entry name" value="PHA_reg_PhaR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PHB_acc_N" evidence="2">
        <location>
            <begin position="21"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="domain" description="PHB_acc" evidence="1">
        <location>
            <begin position="85"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="domain" description="PHB_acc" evidence="1">
        <location>
            <begin position="136"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="194" mass="22044" checksum="50AF19B7D20E7BB5" modified="2018-07-18" version="1">MQGDKFIGITMSSAKKSSEHLIKKYPNRRLYDTQTSTYITLSDVKQLVMDSDVFVVVDAKTNEDLTRSILLQIILDEEAGGSPMFSSAVLSQIIRYYGHAMQGMMGNYLEKNIQAFIDIQHKLAENSVANYDGKPFSPEMWTQFMNIQGPMMQGMMGNYIEQSKSLFVQMQEQMQNQTLGMFTTFPFGADNKPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVB0</accession>
    <name>A0A2S9GVB0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_3603</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 4">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the trans-sulfuration enzymes family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000020">
        <property type="protein sequence ID" value="PRC91665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91665">
        <property type="protein sequence ID" value="PRC91665"/>
        <property type="gene ID" value="S2091_3603"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016765">
        <property type="term" value="F:transferase activity, transferring alkyl or aryl (other than methyl) groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019346">
        <property type="term" value="P:transsulfuration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00614">
        <property type="entry name" value="CGS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000277">
        <property type="entry name" value="Cys/Met-Metab_PyrdxlP-dep_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006235">
        <property type="entry name" value="OAc-hSer/O-AcSer_sulfhydrylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01053">
        <property type="entry name" value="Cys_Met_Meta_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001434">
        <property type="entry name" value="CGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01326">
        <property type="entry name" value="OAH_OAS_sulfhy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00868">
        <property type="entry name" value="CYS_MET_METAB_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="3">
        <location>
            <position position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR001434-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU362118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC91665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="436" mass="46607" checksum="A2315FD1D5D1F7CF" modified="2018-07-18" version="1">MSASNTPGFDTLSLHAGATPDPTTGARATPIYFSSSYVFNDSDHAASLFNMERPGHVYSRISNPTNAVLEERIAALEGGVAGLAVASGQAAMHLGLSTIAGAGSHIVASRALYGGSQNLLAYTLKRFGIETTFVDPRNIDAWRAAIRPNTKVLFGETLGNPGLDVFNIPAIAELAHENQLPLMLDSTFTTPYLLRPFDHGADLLFHSATKFLCGHGTAIGGLLVDGGRFDWQQAYDKTGRFDELCAPYDGFHGMVFAEESSTAAFALRARREGLRDFGACMSPHNAFAILQGIETLSLRMDKHLSNARKIIEFLLAHPAVESVTYPELESHPDYELAKQLLPKGCGAVFTFALKGNRAAGARLVESLKLFSHLANVGDAKSLIIHPASTTHFRVPAEQLAASGITEGTMRLSIGLENVDDLIADLSAGLKAAQKGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVC3</accession>
    <name>A0A2S9GVC3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative proline hydroxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_3601</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>L-ascorbate</name>
            <dbReference type="ChEBI" id="CHEBI:38290"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000020">
        <property type="protein sequence ID" value="PRC91663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91663">
        <property type="protein sequence ID" value="PRC91663"/>
        <property type="gene ID" value="S2091_3601"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031418">
        <property type="term" value="F:L-ascorbic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006620">
        <property type="entry name" value="Pro_4_hyd_alph"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044862">
        <property type="entry name" value="Pro_4_hyd_alph_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13640">
        <property type="entry name" value="2OG-FeII_Oxy_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00702">
        <property type="entry name" value="P4Hc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0847">Vitamin C</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="7">
        <location>
            <begin position="101"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC91663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="199" mass="22870" checksum="8D52F29836D921DE" modified="2018-07-18" version="1">MNLLTSQQRICTDLSNQGWSVLDNCLEPELIRQLAQECRNQHALGSLQDAGIGRAEQRSVQKLVRGDQILWLETGMSAATDMYLTAMDTLRQSLNEQLYLGLESSENHFAVYPPDSFYQKHVDRFRDSDSRTISSVLYLNPEWQPEHGGELRLHLNDQQFDIAPLANRLVLFISADIWHEVLPTKAERLSLTGWFKRRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVM1</accession>
    <name>A0A2S9GVM1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycine/D-amino acid oxidases (Deaminating)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3503</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000019">
        <property type="protein sequence ID" value="PRC91748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91748">
        <property type="protein sequence ID" value="PRC91748"/>
        <property type="gene ID" value="S2091_3503"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DAO" evidence="1">
        <location>
            <begin position="31"/>
            <end position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="427" mass="46852" checksum="C7852548F876B315" modified="2018-07-18" version="1">MSSIPHAASYYADSANPSPDRPSLLAAIEADICIIGAGYTGLSAGLHLAEAGFKVVILEQAKVGWGASGRNGGQIVHSYSRDIDVIEANYGKENAKPLAEMMFEGAKIIRERVTKYNIQCDLKTGGVYAALTKKKINALEEQKALWEKWGNTDLTLIDNRDEIKSVVNTDRYQAILVDKSGGHFHPLNLTLGEAAAIEQHGGVIYENSAVINIERGTNPVVHTALGQVKAKFVIVACNAYIGDLEPKLAKMAMPCGTQVITTEPLGRLADELIPSDYCVEDNNFLLDYYRLSGDKRLIFGGGVIYGARDPSHIEAILRPNMCKVFPQLKNVKIDYSWTGNFLLTLSRMPEVGKLSDNIYYSQGCSGHGITFTHLIGRLLSEAIRGQAERFSAFERLPHYPFPGGRLFRVPLTAMGAAWYDLRDRLGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVN8</accession>
    <name>A0A2S9GVN8_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_3526</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="PUGF01000019">
        <property type="protein sequence ID" value="PRC91771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91771">
        <property type="protein sequence ID" value="PRC91771"/>
        <property type="gene ID" value="S2091_3526"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="160"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="8">
        <location>
            <begin position="182"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="7">
        <location>
            <begin position="242"/>
            <end position="445"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC91771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="445" mass="48865" checksum="CD723B3B1F4BF619" modified="2018-07-18" version="1">MKSFFSRIKNAWPDTLFGRLVLIWLLTFLIGHVLEIGASYTTVLNYQTTKSEYYLSKDIALLVPALEHAQPSERALWLQRMERQDYRYELGAGAAANTIQLTSTRAKEISAALSLALDSRYLISVTAPNTPKELMVLHLPLSDGTPLTIHLNKIALKMPWWGGAIFATQILFLIILTWYALRQAMRPLLRLAEASEALGSSLQCEPIIESGPSEVARAAVAFNAMQRRITEHLAERVHILASISHDLQTPITRMRLRADLLDNGVDNGALRDKLHGDLNAMQVLVEEGIAYARSAHSVNEVPCRVDIDALLDSLTCDYLDDGQQIGLQGKANRVITTRPHALRRIVSNLVDNALKFAEQVEISVMLHTPNLLNISVQDRGPGIPATELDAVLKPFYRLEASRNRSSGGTGLGLAIAQQLSIALGGTLSLSNRDGGGLQATISLPC</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVP6</accession>
    <name>A0A2S9GVP6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3547</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000019">
        <property type="protein sequence ID" value="PRC91792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91792">
        <property type="protein sequence ID" value="PRC91792"/>
        <property type="gene ID" value="S2091_3547"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015734549" evidence="1">
        <location>
            <begin position="26"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="369" mass="40392" checksum="94DAF7E89BD0F725" modified="2018-07-18" version="1">MNVSIFRTFCSVLICGALSACVIPAQIETNKAASYTDEPKRIFVITDIGSEWGKDFANGFQQKMTSIAKVCGADSQFLFVSGLELDSVKPDAQMQAFHPDTLLSIKRVGYILDPTGKVVVTQNYDVRLLDVKTNKTVWRANMKFSGTNGEMISSLMYSKSERGESLAMDMTNRMKDDKIFRSCSKYASLKDTPASIPAQSTAPTATFQPAVPIATITPTIQQSAANDSNVESSIDLPDGWATARLSDALKAKHFTFHATNQGNGATLLISSKKRADVADIQKYAEIQRNAQMNSVVDGKQSEIEMLKMNDLSAWRFTVQGVGKASGKDLTWLITVIENGNKISILTVGAPTDHFSDNRDAFNKLAYLVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVQ6</accession>
    <name>A0A2S9GVQ6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3491</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000019">
        <property type="protein sequence ID" value="PRC91736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91736">
        <property type="protein sequence ID" value="PRC91736"/>
        <property type="gene ID" value="S2091_3491"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036629">
        <property type="entry name" value="YjbJ_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69047">
        <property type="entry name" value="SSF69047"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="61" mass="6592" checksum="E01F519BAFCF008B" modified="2018-07-18" version="1">MNKDQVKGVSKDIAGKIQEDAGKVTGSKSQQLKGLEKQIDGKSEKNLGDAKEIIKDAVKKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVT9</accession>
    <name>A0A2S9GVT9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3395</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000018">
        <property type="protein sequence ID" value="PRC91839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91839">
        <property type="protein sequence ID" value="PRC91839"/>
        <property type="gene ID" value="S2091_3395"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="5"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="64" mass="7277" checksum="0D70D12BB43CDAF4" modified="2018-07-18" version="1">MNNRLKELRLAKELTQQALADTLSVSRQTINSIETGKYDPSLTLAFKLSQLLKVRIEDIFSPDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVW1</accession>
    <name>A0A2S9GVW1_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 13">Flagellar biosynthetic protein FlhB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">flhB</name>
        <name evidence="15" type="ORF">S2091_3410</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12 13">Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="13">Cell membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the type III secretion exporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000018">
        <property type="protein sequence ID" value="PRC91854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91854">
        <property type="protein sequence ID" value="PRC91854"/>
        <property type="gene ID" value="S2091_3410"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044780">
        <property type="term" value="P:bacterial-type flagellum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1690.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006136">
        <property type="entry name" value="FlhB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006135">
        <property type="entry name" value="T3SS_substrate_exporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029025">
        <property type="entry name" value="T3SS_substrate_exporter_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30531">
        <property type="entry name" value="PTHR30531"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01312">
        <property type="entry name" value="Bac_export_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00950">
        <property type="entry name" value="TYPE3IMSPROT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160544">
        <property type="entry name" value="SSF160544"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00328">
        <property type="entry name" value="flhB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 13" id="KW-1005">Bacterial flagellum biogenesis</keyword>
    <keyword evidence="11 13" id="KW-1006">Bacterial flagellum protein export</keyword>
    <keyword evidence="5 13" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="15" id="KW-0966">Cell projection</keyword>
    <keyword evidence="15" id="KW-0969">Cilium</keyword>
    <keyword evidence="15" id="KW-0282">Flagellum</keyword>
    <keyword evidence="10 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 13" id="KW-0653">Protein transport</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 13" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="37"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="83"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="186"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00025078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU364091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="PRC91854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="400" mass="43752" checksum="0944EDD24BD9F17E" modified="2018-07-18" version="1">MAEDSGLERTEPASSRRIEKAREEGDVPRSRELGTCLLLLAAGVGLWLIGGDLVNQISLMLTNSMQFDRSMAFDLPRLFDLQMAHFIQMLIALAPFAGILIVVALISPALIGGWLFSLQALTPNFERMNPLSGLGRMISMRSLVELVKALSKATVVGFVAFQVMRHHYESIIGLASESSKEGLTHVASLIVMCFISISSGLIIIMAIDVPFQLRSYANKLKMTRQEVIQESKEANGNPQIKAKIRSQQREMARRRMMSKVPTADVVVTNPNHYAVALKYIEGRMSAPIVIAKGADLVAARIRELAEEHHIPLLEAPPLARALYAHAELNSQIPESLYTAVAEVLAYVFQLRAYKENGGMAPTLPEVIEVPEELDPTSPAALNLKKSKMNSVTANAGGLNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVX8</accession>
    <name>A0A2S9GVX8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">RDD family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_3416</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000018">
        <property type="protein sequence ID" value="PRC91860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91860">
        <property type="protein sequence ID" value="PRC91860"/>
        <property type="gene ID" value="S2091_3416"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010432">
        <property type="entry name" value="RDD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06271">
        <property type="entry name" value="RDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="34"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="97"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="RDD" evidence="6">
        <location>
            <begin position="2"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF06271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC91860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="154" mass="17917" checksum="75C46F426DA767D4" modified="2018-07-18" version="1">MVYEAVLLFGIYFSACFLFDVLTQNFNAASIRNWRQLFLFVVVGIYFTYFWGRTGQTLPMQTWRIKLVSANQQAITFKQACLRYCCAWMWFLPSLAFIYLFGIQHWPSIIIIFVGMIAWACTVKLDKNGQFLHDKIAGTQLISLPKEARISDTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWE1</accession>
    <name>A0A2S9GWE1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3169</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000016">
        <property type="protein sequence ID" value="PRC92034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92034">
        <property type="protein sequence ID" value="PRC92034"/>
        <property type="gene ID" value="S2091_3169"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009305">
        <property type="entry name" value="Mpo1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28026">
        <property type="entry name" value="PTHR28026"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06127">
        <property type="entry name" value="DUF962"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="94"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="121"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="147" mass="16864" checksum="273B497042C6E950" modified="2018-07-18" version="1">MEEVSKKPVEILIEQYSESHQNPINELIHFICVPAIMWTFLGLFWSLHPLLAVAVTVLALVYYFTLSPRLCFGMLIMSLLMLGLLYALPGSWVLPLSIIVFVLAWIGQFIGHYLEGKKPSFFEDVRFLLIGPLFVLGFLYRKCHFAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWM5</accession>
    <name>A0A2S9GWM5_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Thioredoxin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_3233</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the thioredoxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000016">
        <property type="protein sequence ID" value="PRC92098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92098">
        <property type="protein sequence ID" value="PRC92098"/>
        <property type="gene ID" value="S2091_3233"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015035">
        <property type="term" value="F:protein-disulfide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005746">
        <property type="entry name" value="Thioredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000077">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01068">
        <property type="entry name" value="thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4 6" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Thioredoxin" evidence="7">
        <location>
            <begin position="1"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="6">
        <location>
            <begin position="33"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR000077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000077-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC92098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="108" mass="11737" checksum="16CEC656006C48EC" modified="2018-07-18" version="1">MSENIKHITDASFEIDVLKSDKPVLVDFWAEWCGPCKMIAPILEEVAKEYGGKVIIAKMDVDSNQETPAKFGVRGIPTLILFKNGVAAAQKVGALAKGQLTTFIDSNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWN1</accession>
    <name>A0A2S9GWN1_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 6">Lon protease</fullName>
            <ecNumber evidence="5 6">3.4.21.53</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">ATP-dependent protease La</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">lon</name>
        <name evidence="13" type="ORF">S2091_3049</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 6 9">
            <text>Hydrolysis of proteins in presence of ATP.</text>
            <dbReference type="EC" id="3.4.21.53"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="5 6">Homohexamer. Organized in a ring with a central cavity.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5 6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="induction">
        <text evidence="5">By heat shock.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 6 9 10">Belongs to the peptidase S16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.53" evidence="5 6"/>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92133">
        <property type="protein sequence ID" value="PRC92133"/>
        <property type="gene ID" value="S2091_3049"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034605">
        <property type="term" value="P:cellular response to heat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006515">
        <property type="term" value="P:protein quality control for misfolded or incompletely synthesized proteins"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.130.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01973">
        <property type="entry name" value="lon_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027543">
        <property type="entry name" value="Lon_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004815">
        <property type="entry name" value="Lon_bac/euk-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008269">
        <property type="entry name" value="Lon_proteolytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027065">
        <property type="entry name" value="Lon_Prtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003111">
        <property type="entry name" value="Lon_prtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046336">
        <property type="entry name" value="Lon_prtase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008268">
        <property type="entry name" value="Peptidase_S16_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10046">
        <property type="entry name" value="PTHR10046"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05362">
        <property type="entry name" value="Lon_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02190">
        <property type="entry name" value="LON_substr_bdg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001174">
        <property type="entry name" value="Lon_proteas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00464">
        <property type="entry name" value="LON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="SSF88697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00763">
        <property type="entry name" value="lon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51787">
        <property type="entry name" value="LON_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51786">
        <property type="entry name" value="LON_PROTEOLYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01046">
        <property type="entry name" value="LON_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="evidence at transcript level"/>
    <keyword evidence="5 6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 6 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 6 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2 5 6" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5 6" id="KW-0720">Serine protease</keyword>
    <keyword evidence="4 5" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="Lon N-terminal" evidence="12">
        <location>
            <begin position="12"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="domain" description="Lon proteolytic" evidence="11">
        <location>
            <begin position="592"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="active site" evidence="5 7 9">
        <location>
            <position position="679"/>
        </location>
    </feature>
    <feature type="active site" evidence="5 7 9">
        <location>
            <position position="722"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5 8">
        <location>
            <begin position="356"/>
            <end position="363"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR001174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR001174-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR001174-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PRC92133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="802" mass="89060" checksum="8C7FC03B334D4AB1" modified="2018-07-18" version="1">MTTSLPTEHTQLPLLPLRDVVVFPHMVIPLFVGRPKSIKALEAAMEQGKSILLAAQKAAAKDEPSPDDIYEIGCIANILQMLKLPDGTVKVLVEGVQRARINQIRELDTHFVANLIPVETEESDDSEVEAMRRAIVQQFDQYVKLNKKIPPEILASLSGIDDAGRLADTVAAHLPLKLDQKQEILEIFSVAKRLEHLLGQLEGELDILQVEKRIRGRVKRQMEKSQREYYLNEQVKAIQKELGEGEEGADLEEIDKKIIAAKMPKEAKDKAMGELKKLKMMSSMSAEATVVRNYIDTLINLPWKKKSKVTNDLAHAEKVLDADHYGLDKVKERVLEYLAVQQRVDKLKAPILCFVGPPGVGKTSLGQSIARATNRKFVRMALGGVRDEAEIRGHRRTYIGSMPGKILQSLSKIGVRNPLFLLDEVDKMGADFRGDPSSALLEVLDPEQNHTFSDHYLEVDFDLSDVMFVATSNSYNIPAALLDRMEVIRLSGYTEDEKSSIAQRYLLPKQIKNNGLKEEEISISETAIKDIIRYYTREAGVRSLEREISKICRKVVKMLLLKKQEKKVTITCKNLDKYLGVRRYDFGMAVKENQVGQVVGLAWTEVGGDLLTIEAVSMSGKGNVIRTGTLGDVMKESIEAARTVVRSRSARLGIKADVFEKTDVHIHVPEGATPKDGPSAGIAMTTALVSIFTGIPVRADVAMTGEITLRGEVLPIGGLKEKLLAAHRGGIKTVIIPEENAKDLVEIPDNVKNHLEIIPVRWIDRVLEIALERQPTPLVEEEVVVSAKPAVPGEVVDPVVKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWT9</accession>
    <name>A0A2S9GWT9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">YXWGXW repeat (2 copies)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3084</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92168">
        <property type="protein sequence ID" value="PRC92168"/>
        <property type="gene ID" value="S2091_3084"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024447">
        <property type="entry name" value="YXWGXW_rpt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12779">
        <property type="entry name" value="WXXGXW"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015555354" evidence="2">
        <location>
            <begin position="23"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="235"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="289" mass="31409" checksum="05EDC08864091E20" modified="2018-07-18" version="1">MHKIIIQLTLAAALVTPFIAQADVSLSINIAPPALPIYAQPAIPGDGYLWTPGYWSWNDADADYYWVPGTWVVAPFVGALWTPGYWGWANGGYAWHGGYWGTHIGYYGGINYGYGYVGVGYQGGHWNNGVFNYNRSVNNVGNRHITNIYNSRVVNTTVNRVSYNGGQGGVRLQPTKAEEVIAGMPHKVQTPLQTQHESAARGNQVQRASVNHGVPKVAATPEPNAFNAPNVVAARVAQAASSHHSPAGNAQHPQARAPKHEEQQASHSEPHPAQHSAPHEGNQHEEEHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWZ0</accession>
    <name>A0A2S9GWZ0_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ribonuclease E</fullName>
            <shortName evidence="5">RNase E</shortName>
            <ecNumber evidence="5">3.1.26.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rne</name>
        <name evidence="8" type="ORF">S2091_3148</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>Endonucleolytic cleavage of single-stranded RNA in A- and U-rich regions.</text>
            <dbReference type="EC" id="3.1.26.12"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="5">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="5">Binds 2 Zn(2+) ions per homotetramer.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homotetramer formed by a dimer of dimers.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Cell inner membrane</location>
            <topology evidence="5">Peripheral membrane protein</topology>
            <orientation evidence="5">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the RNase E/G family. RNase E subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.26.12" evidence="5"/>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92232">
        <property type="protein sequence ID" value="PRC92232"/>
        <property type="gene ID" value="S2091_3148"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009898">
        <property type="term" value="C:cytoplasmic side of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004521">
        <property type="term" value="F:endoribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008995">
        <property type="term" value="F:ribonuclease E activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006402">
        <property type="term" value="P:mRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00970">
        <property type="entry name" value="RNase_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019307">
        <property type="entry name" value="RNA-bd_AU-1/RNase_E/G"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028878">
        <property type="entry name" value="RNase_E"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004659">
        <property type="entry name" value="RNase_E/G"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022967">
        <property type="entry name" value="S1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30001">
        <property type="entry name" value="PTHR30001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10150">
        <property type="entry name" value="RNase_E_G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00575">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00757">
        <property type="entry name" value="RNaseEG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="1 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0540">Nuclease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="5" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="5" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="5" id="KW-0820">tRNA-binding</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="S1 motif" evidence="7">
        <location>
            <begin position="39"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Required for zinc-mediated homotetramerization and catalytic activity" evidence="5">
        <location>
            <begin position="402"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="580"/>
            <end position="769"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="996"/>
            <end position="1017"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="589"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="630"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="659"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="695"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="713"/>
            <end position="740"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="301"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="344"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="402"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="405"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC92232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="1017" mass="111254" checksum="22C826B0023E8BA4" modified="2018-07-18" version="1">MKRMLFNATQQEELRVAIVDGQKLIDIDIETAGRELRKSNIYKGVITRIEPSLEACFVNYGEDRHGFLPFKEVARGYFKEGADPRNSSIKEALREGQEIMVQVEKEERGNKGAALTSFVSLAGRYLVLMPNNPRGGGVSRRVEGEDRQELRDTMDKLDLPGGMSVIARTAGIGRNVDELQWDLNYLMQLWRAIEGANKSASGAFLIYQESSLVIRAIRDYFQPDIGEILIDTDDIYEQAQQFMSHVMPDMVHRVKRYSDDVPLFSRFQIEHQIETAYSRTVPLPSGGAIVIDHTEALVSVDVNSARATRGSDIEATAFNTNCEAAEEVARQLRLRDLGGLIVIDFIDMENAKNQREVETRLKDALRYDRARVQMGKISRFGLMELSRQRLRPSLSEGSHVTCPRCNGTGHIRDTESSALQVLRIIQEEAMKENSAAIHVQVPVDVAAFLLNEKRGEILKIETRHRVTAILIPNKHLETPHYKLDRLKSDDPRLEETHASYAMAEQVDTDIGYNKRNKEDLKPRQEAVVKSITPETAPIVERKEVVAAKAATASATPTKQVGFFARVMGWLSGSSTATVEAPVAPVKTTGKPERETRDSNDRNNRNRNSRNSRNSRNSRDPEERAATPNAPVAANSKQAKPVVTSDANTGDAAQRPAKAPRPPRAERESQEARRERQQREREERAAKKAANAALNTAQDPVLSNKTVAEPVTNTDADTEEKLDLLADGENNEAGGDEPRRRRRRGGRNRNRRDRETGENGATEQAPRDNSEDFIPVADIAHAEQHQASVIAHESAANAHAPMAPAAVAHVAESPVTAVVASPVENQVEQKAAEVVIAAAPVTPVATAPAAVVFSEVVNAVLPVITSIESAKPAEPLHSEPVAAPVSIPEPPAVVIPAQVELKFEPVAEIAPIAEVAPVAPVAPVAAVQAVVAPAVVEAPAAAPTPTVNHAPVVAKVEDLQDMLKSAGLVLAATDPSKLLSAQTMAAPVAEVRKPRLRKPPVEVTNEPLELIQTKHDNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GX04</accession>
    <name>A0A2S9GX04_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2912</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92253">
        <property type="protein sequence ID" value="PRC92253"/>
        <property type="gene ID" value="S2091_2912"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019621">
        <property type="entry name" value="DUF2491"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10679">
        <property type="entry name" value="DUF2491"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="264" mass="29190" checksum="8ACDBB84176041C7" modified="2018-07-18" version="1">MSWKDAFQYGKAVLANHGVEAAKDAPRADDALPLGARIGALIKLQQSPFIRANANGSLIAMPDQAEATIRAISHVKLNLSGQLYRYYLSLGDSDDEAEIFLQLFQDEHGAISELMYCTRLTRLIPQTAEEQEAYTGESGFGLGEKTYAIWKEQLADLGYSEAELSAVFGDAENVEYRRDVGAANVDFVTPFNGIETRIDDTAGEHGLKQEIYFMPYVRNLADGLEYLLISTEIVESQNGDSDKRAIHVNFMIGLALEAERVVIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GX31</accession>
    <name>A0A2S9GX31_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">GGDEF: diguanylate cyclase (GGDEF) domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_2917</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92258">
        <property type="protein sequence ID" value="PRC92258"/>
        <property type="gene ID" value="S2091_2917"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007892">
        <property type="entry name" value="CHASE4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05228">
        <property type="entry name" value="CHASE4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="277"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="2">
        <location>
            <begin position="295"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="3">
        <location>
            <begin position="385"/>
            <end position="519"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC92258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="520" mass="57859" checksum="343844A4D0C55270" modified="2018-07-18" version="1">MGLRGKMFGLFLIGFGLMTIIVMTLLYSNLLHGFMAIERTQATEQMTQLARNLDSELDRLNQINGDWANWDDMVSYTQQPTHGFIEHQLNSAELQTVGLKFIFILDKQDNILFSNATNLVTGAMESASTFDPILANIKVRLHPESAPDNGRTCGLDNSTAGPVLVCWQQIHQTDHSGKPMGCLVVGQLLNSTILKRIQDQSGLKFELMPQTIRATEPPHSIKASIEPEMLEFSQSAPNILSAHLYNIVGQPILIARLQFSREVGQLGNDIIWKVMRVVLLVTALTGLTLLAGIHFLVIRRLRKMKIELNSIWRNGRWAGRLDTPKNKDELNELAHSINRMLALIRKQMGILESIAHTDALTQIANRRAFDQRMAIEMSLHKRNQTPLSLLLIDVDYFKRYNDYYGHPAGDEVLKEIGKLLIQVACRPSDLPARIGGEEFAVILPATDLAGAGHVAEKIRVHLAELKLAHADSPASDYVTISIGATIAGEEDLASFIQRADKATYQAKQSGRNKINVLPAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXI2</accession>
    <name>A0A2S9GXI2_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 9">3-deoxy-D-manno-octulosonic acid transferase</fullName>
            <shortName evidence="9">Kdo transferase</shortName>
            <ecNumber evidence="3 9">2.4.99.12</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6 9">Lipid IV(A) 3-deoxy-D-manno-octulosonic acid transferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">S2091_2809</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>CMP-3-deoxy-beta-D-manno-octulosonate + lipid IVA (E. coli) = alpha-Kdo-(2-&gt;6)-lipid IVA + CMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:28066"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58603"/>
            <dbReference type="ChEBI" id="CHEBI:60364"/>
            <dbReference type="ChEBI" id="CHEBI:60377"/>
            <dbReference type="ChEBI" id="CHEBI:85987"/>
            <dbReference type="EC" id="2.4.99.12"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 9">Bacterial outer membrane biogenesis; LPS core biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the glycosyltransferase group 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.99.12" evidence="3 9"/>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92434">
        <property type="protein sequence ID" value="PRC92434"/>
        <property type="gene ID" value="S2091_2809"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00958"/>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043842">
        <property type="term" value="F:Kdo transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009244">
        <property type="term" value="P:lipopolysaccharide core region biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11720">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007507">
        <property type="entry name" value="Glycos_transf_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038107">
        <property type="entry name" value="Glycos_transf_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039901">
        <property type="entry name" value="Kdotransferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42755">
        <property type="entry name" value="PTHR42755"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04413">
        <property type="entry name" value="Glycos_transf_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9" id="KW-0448">Lipopolysaccharide biosynthesis</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycos_transf_N" evidence="10">
        <location>
            <begin position="33"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="61"/>
        </location>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="8">
        <location>
            <position position="136"/>
        </location>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="8">
        <location>
            <position position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004713"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012621"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00019077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00031445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR639901-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR639901-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF04413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC92434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="424" mass="47280" checksum="98FA7FBA65E63FCA" modified="2018-07-18" version="1">MRILYTFVWILALPLVLARLFWRGRLEPGYRQHIAERFGFYSAASKPKQAVIWVHAVSVGETRAAEPLIKQLMQAYPQHRILLSHMTPTGRATGALLFANELSNNTVQQCFLPYDIPYLVRRLLTHFKPTICILMETEVWPNLIYACRQQAVPVTLVNARLSPKSLKKAERLSSLILPASAALTCVAAQTEADAKRILQLGAPKVLVTGNSKFDVSLNPEQISAGHTLREQFGSRPVLLCASTREGEEDLILDAFMQVQNSNLLLIIVPRHPQRFDLVEQLIKQRGLTMERRTTLAQNKLADEVRVVLGDTMGEMASYYVSSDIAFIGGSLLPLGGQNLIEACAVEKPVLIGPHTFNFEAISVDAIEAKGALRIYNAAQLFEETGKLIQDRERKTTMGKCALAFAEQHRGATARTLALLREYIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXK0</accession>
    <name>A0A2S9GXK0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">[2Fe-2S] binding domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2819</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92444">
        <property type="protein sequence ID" value="PRC92444"/>
        <property type="gene ID" value="S2091_2819"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016209">
        <property type="term" value="F:antioxidant activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00207">
        <property type="entry name" value="fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002888">
        <property type="entry name" value="2Fe-2S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036884">
        <property type="entry name" value="2Fe-2S-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006058">
        <property type="entry name" value="2Fe2S_fd_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000866">
        <property type="entry name" value="AhpC/TSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
        <property type="entry name" value="AhpC-TSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00111">
        <property type="entry name" value="Fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01799">
        <property type="entry name" value="Fer2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47741">
        <property type="entry name" value="SSF47741"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="SSF54292"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00197">
        <property type="entry name" value="2FE2S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="2">
        <location>
            <begin position="228"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="381" mass="41474" checksum="31368A3D799DA16B" modified="2018-07-18" version="1">MYAPPPPCSRYDITTLYEIEPEAQIGSLAPDFYLPERFQHRHFSELRGTPVIMVFSPSVWDPSAAEQLSFLKNLLAYCAPTYVNLRELSFENENYFLKFDLPQASTMIAVLHDFDPSGGIAHAYGVYGERAVIVVDAEGFLRERYVIPVGTMPRIDPLRQALEILGNDYGSVATGSTGQIMQVNRRQFLASAIAASLTLWIWPNIALADTPTGNPKSKSNALIPPTSRALTLKINGEFHTLNLDTRVTLLDALRENLGLTGTKKGCDQGTCGACTVLVDGRRIKACLTLAAMEEGKQITTIEGLAEGGQLHPMQQAFIDTDALQCGYCTPGQIMSAVALMHEGHAGNDDEIREWMSGNICRCGAYAGIVAAISNVAKGVKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXN7</accession>
    <name>A0A2S9GXN7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative conserved protein contains double-stranded beta-helix domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2859</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92484">
        <property type="protein sequence ID" value="PRC92484"/>
        <property type="gene ID" value="S2091_2859"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013096">
        <property type="entry name" value="Cupin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07883">
        <property type="entry name" value="Cupin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cupin_2" evidence="1">
        <location>
            <begin position="47"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="159" mass="17590" checksum="48B04EDAAA4233E1" modified="2018-07-18" version="1">MTVINSKVANIGEMKLEHFEKGDTFESNSVRIGTLLGAKDLGYSYDVVPPGKRSCPFHSHRGEEEMFFIVKGSGTLRYGSETRKIREGDVICCPTGGPETAHQIVNDSDADLAYLSVSTKMAAEVCEYPDSNKIGAYGGNLRHLTRIEHDLDYWTDEVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXN8</accession>
    <name>A0A2S9GXN8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Outer membrane efflux protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2854</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92479">
        <property type="protein sequence ID" value="PRC92479"/>
        <property type="gene ID" value="S2091_2854"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015562">
        <property type="term" value="F:efflux transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003423">
        <property type="entry name" value="OMP_efflux"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02321">
        <property type="entry name" value="OEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="156" mass="17722" checksum="99D1C7955D83A788" modified="2018-07-18" version="1">MHNSRSRPIPRSTTPALWVSRFRRWVNFRSAAIPLFDGVSHSYRVQAAKAKYESKAAELANLEIRISLEVWKDYYAMEMETENLKLSAELEDSASLSFNVSQGRYKYGVGNILELLTAQTVLINARQQKISVLSNWRSARIKLAASLGKLGMWAVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXU4</accession>
    <name>A0A2S9GXU4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Deacetylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2599</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the histone deacetylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92544">
        <property type="protein sequence ID" value="PRC92544"/>
        <property type="gene ID" value="S2091_2599"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.800.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000286">
        <property type="entry name" value="His_deacetylse"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023801">
        <property type="entry name" value="His_deacetylse_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037138">
        <property type="entry name" value="His_deacetylse_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023696">
        <property type="entry name" value="Ureohydrolase_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00850">
        <property type="entry name" value="Hist_deacetyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01270">
        <property type="entry name" value="HDASUPER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52768">
        <property type="entry name" value="SSF52768"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hist_deacetyl" evidence="2">
        <location>
            <begin position="20"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="308" mass="33740" checksum="156A38DD81A34BDC" modified="2018-07-18" version="1">MTTAFYTHPACKLHEMGADHPESPLRLSTIDDYLITSRIDDLVLHCEAPLATEDELALVHTRGTIARIKEHTPEFGYYPLDGDTLLNPSSWTAARAAAGAAIAATKAVLDGEVENAFCSIRPPGHHATPDEAMGFCLFNNLALAAKHALDVHGLERIAIVDFDVHHGNGTQAVFENDPRVLMVSFFQHPCYPYSGTEFISKNMLNLPVPAYTDGALIRSLVEQHWLPALHAHQPQMIFISAGFDAHREDLIGQLGLVEADYAWITMQIMQIAKQYSFSRVVSCLEGGYNTSALGRSVVAHIKVLAGLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GY38</accession>
    <name>A0A2S9GY38_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">Recombination-associated protein RdgC</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rdgC</name>
        <name evidence="6" type="ORF">S2091_2684</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 5">May be involved in recombination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 5">Cytoplasm</location>
            <location evidence="2 5">Nucleoid</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 5">Belongs to the RdgC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92629">
        <property type="protein sequence ID" value="PRC92629"/>
        <property type="gene ID" value="S2091_2684"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009295">
        <property type="term" value="C:nucleoid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00194">
        <property type="entry name" value="RdgC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007476">
        <property type="entry name" value="RdgC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38103">
        <property type="entry name" value="PTHR38103"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04381">
        <property type="entry name" value="RdgC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC92629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="298" mass="32958" checksum="766DB0B2EF20E415" modified="2018-07-18" version="1">MWFKNLQVYRVAKSFKAQIPVLNAQLSTHQFQPCGASESASQGWSAPREHGDLVHLVNQQVLLCFTTEKKVLPSSVINAAVKARAQEVEEQQGFKPGRKLLKELKEQVTEELLPRAFASRTNTSVWIDPVNGWLVIDASSPGRSDEVLKLMLKCIDQFPIESLRVNLSPLGAMTDWLSGNEAPDGFTIDQDAELRSSGQSKATVKYTRHNLDPVEIANHIAGGKQCTKLALTWNDKVSFVLTENLAIKRVRALDVLTEKSNAQHEDERLDGDFVLMCGELNGLLNDLVLALGGEAVNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GY98</accession>
    <name>A0A2S9GY98_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Prepilin-type N-terminal cleavage/methylation domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2749</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92694">
        <property type="protein sequence ID" value="PRC92694"/>
        <property type="gene ID" value="S2091_2749"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="187" mass="21036" checksum="90B3AEEAAA266825" modified="2018-07-18" version="1">MFGLPYHHPPYRLLACNPTLSRPNDMLPQQLGRISGFTLIELLVTLAILGVLASMTAPIAQVARQRVQEQELRLALREIRQGIDAYQRATNDGRIPKPIGSNGYPKELNILVEGVSDQRDPKRNKIFFLRRVPRDPMNTNTNTPEATSWGLRSYASEATDPQEGEDVYDVYSTSTKVGLNGVPYNKW</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYB5</accession>
    <name>A0A2S9GYB5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Peptidase family M48</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_2447</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="6">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the peptidase M48 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92717">
        <property type="protein sequence ID" value="PRC92717"/>
        <property type="gene ID" value="S2091_2447"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001915">
        <property type="entry name" value="Peptidase_M48"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01435">
        <property type="entry name" value="Peptidase_M48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 6" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1 6" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="4 6" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015698142" evidence="7">
        <location>
            <begin position="27"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M48" evidence="8">
        <location>
            <begin position="79"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC92717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="285" mass="31486" checksum="11A06B934818A759" modified="2018-07-18" version="1">MNTLYRLSKYISAAALLSIFYSSASAQFNLQIPGLGNIGKLLDTTTKTFKEVDEPEEIRIGQEFASILLGAKPLEPDQRKQRYVNALGRWLALQTERPDLPWTFAVLDDPSFNAFATPGGYIFVTRGLLERMHNEAELAGVLSHEIGHVLRKHHLHAVQKNSAFSAAGDYFTSSTGGNAQVKSAVSGAIRNMLVKGLDKDDEYEADRIGVVIAARAGYDAYGLPSVLQTLQKQSSQDNNFTLLFKTHPLPADRLTQLDQLMGQQFDTLPGISGKTIEERLKEFGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYF1</accession>
    <name>A0A2S9GYF1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2741</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92686">
        <property type="protein sequence ID" value="PRC92686"/>
        <property type="gene ID" value="S2091_2741"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="85"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="120" mass="13469" checksum="3C6987B5E72F2181" modified="2018-07-18" version="1">MQKQIDAINERLDAGQGKFGEVADALSKITAHLQSQDAAMSLMADKVNQNAEGTQSILEMWNGGVKTVRFFCRLAEGWRFFIREMLIPVFLPLMGIGVVIYYFNHGDFPKWAAALFKLIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYH4</accession>
    <name>A0A2S9GYH4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2488</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92758">
        <property type="protein sequence ID" value="PRC92758"/>
        <property type="gene ID" value="S2091_2488"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="64"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="111"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="142"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="2">
        <location>
            <begin position="198"/>
            <end position="410"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="426" mass="47060" checksum="86CC4900362BAB6E" modified="2018-07-18" version="1">MLRLIQLRWLAVIGQISTIIIAKFVLHIHLPTPDMLTIIACLIAFNIGSTLRWQESVTVTNGELFFALFVDVIMLTGQLYLSGGTNNPFIFLYLLQVIISAMLLESWSTWFIIAITSVCIAGLSEFYVPVEFPYGDEGIYNLYVQGLIICFVLDAALLTFFINRISANLRAGEAQLADLRQRAAEEDHIVRMGLLASGAAHELGTPLATLSVILGDWQHMPQFTSNEELRQEIDVMQAQLFRCKNIISDILLSTGEVRGDSSAKTTLNTFLNTLAEEWGNTRPANSFVFENHIGEDIPVVFDSSLKQMIYNVLDNAAEASPAWVKLQASYEVDILTLVVTDIGPGFLPEMLTQFGKPYQSSKDRPGRGLGLFFAVNVARKLGGKVDVSNYKNKDGNVGGASVQMTLPLSAIHLKTSVNEGNKQYDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYQ5</accession>
    <name>A0A2S9GYQ5_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Methionine--tRNA ligase</fullName>
            <ecNumber evidence="16">6.1.1.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">Methionyl-tRNA synthetase</fullName>
            <shortName evidence="16">MetRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="primary">metG</name>
        <name evidence="20" type="ORF">S2091_2584</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 16">Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 16">
            <text>ATP + L-methionine + tRNA(Met) = AMP + diphosphate + L-methionyl-tRNA(Met)</text>
            <dbReference type="Rhea" id="RHEA:13481"/>
            <dbReference type="Rhea" id="RHEA-COMP:9667"/>
            <dbReference type="Rhea" id="RHEA-COMP:9698"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78530"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.10"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="16">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="16">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5 16">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 16">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 16">Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.10" evidence="16"/>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92854">
        <property type="protein sequence ID" value="PRC92854"/>
        <property type="gene ID" value="S2091_2584"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004825">
        <property type="term" value="F:methionine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006431">
        <property type="term" value="P:methionyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07957">
        <property type="entry name" value="Anticodon_Ia_Met"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00814">
        <property type="entry name" value="MetRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02800">
        <property type="entry name" value="tRNA_bind_EcMetRS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00098">
        <property type="entry name" value="Met_tRNA_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041872">
        <property type="entry name" value="Anticodon_Met"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013155">
        <property type="entry name" value="M/V/L/I-tRNA-synth_anticd-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004495">
        <property type="entry name" value="Met-tRNA-synth_bsu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023458">
        <property type="entry name" value="Met-tRNA_ligase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014758">
        <property type="entry name" value="Met-tRNA_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015413">
        <property type="entry name" value="Methionyl/Leucyl_tRNA_Synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033911">
        <property type="entry name" value="MetRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029038">
        <property type="entry name" value="MetRS_Zn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002547">
        <property type="entry name" value="tRNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45765">
        <property type="entry name" value="PTHR45765"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08264">
        <property type="entry name" value="Anticodon_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09334">
        <property type="entry name" value="tRNA-synt_1g"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01588">
        <property type="entry name" value="tRNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01041">
        <property type="entry name" value="TRNASYNTHMET"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="SSF47323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57770">
        <property type="entry name" value="SSF57770"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00398">
        <property type="entry name" value="metG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00399">
        <property type="entry name" value="metG_C_term"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50886">
        <property type="entry name" value="TRBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="15 16 18" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="12 16 18" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 16" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 16 18" id="KW-0436">Ligase</keyword>
    <keyword evidence="9 16" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 16 18" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14 16 18" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13 16 17" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="7 16 17" id="KW-0820">tRNA-binding</keyword>
    <keyword evidence="11 16" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="TRNA-binding" evidence="19">
        <location>
            <begin position="579"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'HIGH' region" evidence="16">
        <location>
            <begin position="12"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'KMSKS' region" evidence="16">
        <location>
            <begin position="332"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="143"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="146"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="156"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="159"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="335"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="RuleBase" id="RU363039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="PRC92854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="685" mass="76358" checksum="0193D70C8709CC91" modified="2018-07-18" version="1">MTRQLFVTTALPYANAAFHLGHIMEYIQADIWVRHQRMMGNAVHFVCADDAHGAPIMIAAEKANLTPQQFVAQIASGRKQYLDGFHISFDNWHSTDGAENHELSQDIYRKLKAAGFIASKVIEQFYDPVKNMFLADRYIKGECPKCHAKDQYGDSCEVCSAVYSPTELINPYSVLTGAVPVMKSSEHFFFKLSDPKCVAFLREWAIDGNRLQSEVANKAREWLDGEDGLGDWDISRDAPYFGIEIPDQPGKYFYVWLDAPVGYLASLKNYFNKIGRDFDAFMADPATEQIHFIGKDITYFHTLFWPAMLKFSGYKTPDRVYAHGFVTVSGEKMSKSRGTGISPLKYLDIGMNPEWLRYYLAAKLNAKVEDIDFSAEDFTARINSDLIGKFVNIASRAAGFISKRFNGQVNTLWATDTDSFLTSIRSIAPEIQALYEGREYGKALRAIMEQADIINAYVDANKPWILAKDPANDAALQEVCSRLLEAFRILTLYLKPVLPEVAAQVESWLNIAPMQWSDVATTLPNGHTIKPYQHLLTRVEPSIFEALFDAPTAPVAEDSAEKAASANIEELSAEISIDDFTKIDLRIAKIIDCVAVEGSTKLLQLTLDIGDGRTRNVFSGIKSAYQPEQLIGKLTVMVANLAPRKMKFGVSEGMVLAASASDEKANPGLYILEPWPGAVPGMRVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZ20</accession>
    <name>A0A2S9GZ20_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Filamentous hemagglutinin family N-terminal domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2399</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92982">
        <property type="protein sequence ID" value="PRC92982"/>
        <property type="gene ID" value="S2091_2399"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024973">
        <property type="entry name" value="ESPR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008638">
        <property type="entry name" value="Filamn_hemagglutn_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011493">
        <property type="entry name" value="GLUG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041286">
        <property type="entry name" value="MBG_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13018">
        <property type="entry name" value="ESPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07581">
        <property type="entry name" value="Glug"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05860">
        <property type="entry name" value="Haemagg_act"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18676">
        <property type="entry name" value="MBG_2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00912">
        <property type="entry name" value="Haemagg_act"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="SSF51126"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01901">
        <property type="entry name" value="adhes_NPXG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Haemagg_act" evidence="2">
        <location>
            <begin position="69"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1615"/>
            <end position="1650"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="1682" mass="166432" checksum="CDFC2F4785376916" modified="2018-07-18" version="1">MKKHGSMNHIFRLVWSQVLNTWVAVAETTKGRGKGKNSRRKLIAASLSLTALSFAMPVAHAGPTALPAVNTLPSGYQVTAGSATVSSSGNTLNVQENGQRAAINWQTFSIGSNATVNFIQPNSSSVMLNRVVGNEQSVISGALNANGQVFLLNSNGLLFTKGASVNTGGLVASTLNISDSDFMAGRTTFTSNGSHSSVINQGTINAADGGYVAMLGNHVTNQGLITARLGTAILAAGDQVSLNFNGNSLVNVVVNKGTLNALVANQQAIIADGGLVILTAKGADTVLASAVNNTGEIRAQTIANQSGKIYLLGDMQNGTTNVSGTLDASAPNGSNGGFIETSAAHVRVTNDTKITTAAAMGLAGSWLIDPHDFTIAATASGTVTSGTPSGDISGATLGSALNNGNVTILSSQGSTVSGSGNINVNDTVTWAAHTLTLTAANNININAVMTASGAASLAMNPSTTNGGDTAVAGGTVLVGLNNSGFTGAVNFSGSGTLSIGGTIFTVINNSTSNSAGMTALQNINSGLSGNYVLGSNLDATGFTFTPIGTGLGAPFVGVFDGLGHTISNLTINLPSGAGVGLFGYGSLSSLPIRNVGLVNENVTGHYYVGGLIGYNYGAAISNCFVKNGTIIGQNYVGGLVGSNYNLISNSYSTGSLSGSYGYSAGGLVGANYGTVKNSYSTAGLSFPGIYTYYNGGLVGYNAGTVTNSYATGSVSGGGYYVGGLVGLNENGSINNSYSTGNANGKQYVGGLVGENLTGTINNTYSTAASVTATIPGDTGGLVGQNSGNVINSFFIGSGTAVSDNTGTVTGTSGLTSAQMMQQSNFVPAGTGANQWDFTNTWVMYNGSTTPLLQVFMTPLTVTANSSSTTYTGLAQSGSGVTYSVSPNMSNLMGTVGYSGTGTTIGTYTITPSGLFSNQQGYIITYASGTQTITPAPLTITASNVTKTYGQTPSLSAFTSSGLVNGETVGSVTETSAGTSATAGVPGSPYSITASAASGGTFSASNYVISYVNGGLTVTPASLTITASNATKTYGQTPSLSAFTSSGLVNGETIGSVSETSQGTSETAGVTGSPYNITASAASGGTFSASNYVISYVNGGLTVTPASLTITASNATKTYGQTPSLSAFTSSGLVNGETIGSVTETSAGTSATAGVPGSPYSITASAATGGTFSASNYTINYVNGGLTVTPAALTITASNATKTYGQTPSLSAFTSSGLINGETIGGVTETSTGAAVTTGVTGSPYSITASAASGGTFSANNYTINYVNGGLTVTPASLTITASNATKTYGQTSSVSAFTSSGLVNGETIGSVTETSAGTSATAGVTGSPYNITASAASGGTFSASNYTINYVNGGLTVTPASLTITASNTSKTYGQTPSLSAFTSSGLVNGETIGGVTETSTGAAVTAGVTGSPYSITASAASGGTFSASNYVISYVNGSLAVTPLAVSVGTVSGASRTFDGTASVASSLLTITNLINGDTATLTGNGTLASSGVGAEALTGLTGLSLNNPNYTLTAGTPSGTVNITAVVSSTDSSGTTNLGSVVANATIQGQTAITLPNPVVTQIGQGSANGQVSNYVNVVNPLPQISAAFNGNTQLAIISAPGENEPTQVVSMSQARAMMQPSGSATNSDGTTSDSGQGGSNTSDVRVPVSRNSLVDIVNGGVRLPNGVEQQLFVVKGQNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZ78</accession>
    <name>A0A2S9GZ78_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Saccharopine dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2125</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93039">
        <property type="protein sequence ID" value="PRC93039"/>
        <property type="gene ID" value="S2091_2125"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032095">
        <property type="entry name" value="Sacchrp_dh-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005097">
        <property type="entry name" value="Sacchrp_dh_NADP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16653">
        <property type="entry name" value="Sacchrp_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03435">
        <property type="entry name" value="Sacchrp_dh_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sacchrp_dh_NADP" evidence="1">
        <location>
            <begin position="6"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="domain" description="Sacchrp_dh_C" evidence="2">
        <location>
            <begin position="125"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="363" mass="39987" checksum="11150559EAC65408" modified="2018-07-18" version="1">MKTKLILLGAGKIGDAILNLLSHTGEYQITVADRDTARLDYVTKAAFPNTTCVQIDLSDKLAVTEIIRGHQITMSACPYFLTPIIATAAKQAKSHYFDLTEDVESTRLVKQLAENAETAFVPQCGLAPGFISIVANDVAKRFDSLRDVSMRVGALPTFPNNALKYNLTWSTDGLINEYCNPCEAIVDGQLRETSPLEELEHFSLDGINYEAFNTSGGLGTLCESLKGKVQNLNYKTVRYPGHRDIVKMLVRDLQLGQLDRRPILKEVLETAIPITKQDVVLVFVSVSGIREGRLEQESYAKKIYSQTVNGQLLSAIQLTTASGICAMVDMLVHGKLPQSGMVRQEEATLADFLANRFGQYYAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZB2</accession>
    <name>A0A2S9GZB2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Pathogenicity locus</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2129</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93043">
        <property type="protein sequence ID" value="PRC93043"/>
        <property type="gene ID" value="S2091_2129"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021725">
        <property type="entry name" value="Cdd1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11731">
        <property type="entry name" value="Cdd1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="93" mass="10783" checksum="733254D9849CFBBB" modified="2018-07-18" version="1">MPNTNRSHIKKLEDLPNVGKATAADLRLLGIERAEQLRGQDPHNMYVRLCELTGKRHDPCVLDMFIAVVQYMEGGPELPWWAHTEERKKNYKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZD0</accession>
    <name>A0A2S9GZD0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2178</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93092">
        <property type="protein sequence ID" value="PRC93092"/>
        <property type="gene ID" value="S2091_2178"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015747931" evidence="1">
        <location>
            <begin position="21"/>
            <end position="409"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="409" mass="43605" checksum="9336B08709E235A5" modified="2018-07-18" version="1">MNRLIAALLIFLIFCDISSAAVTVKSFTADIQKEKNEINLSDELNSFFKNSGCSLPKALIKKLDKQDKAYIPGELKNLMSGNMTSEVDKYSGKGVLAVLNTAWFVNAQSVSIQVTLTGAETYINYDPLGNMDMQADNFAYAMDCSGFLNSSISSAGGISGSDAAMAAKSALEIKKSMLAVKASVFSPIALAISPDIGGNLSRRQRISVLYSLSREINGLYVDAPDTTKVSSGRMIPAIWTSSAGASSLQGEASLSSNLGASVGVFSASANVAGNATFSKSISFSKFDTYIINSQEIPTIGSDLKAINDTTVQLVNSTTIANPVRRIDSSYQALFDLPSQICKKIWTIKSFKSQDVVVPGTVQTTWDGLKGCEVTINPISALGNDEIGLVLETSSDLKPDLKFVLKVPIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZD7</accession>
    <name>A0A2S9GZD7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phage-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2180</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93094">
        <property type="protein sequence ID" value="PRC93094"/>
        <property type="gene ID" value="S2091_2180"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010265">
        <property type="entry name" value="Phage_lambda_TipM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05939">
        <property type="entry name" value="Phage_min_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="110" mass="12121" checksum="B6AB28923739214D" modified="2018-07-18" version="1">MKTFTWKPISETTGSTQFRVLKAPFGDGYAQTAADGINNKSESWPLSFIAKSNVIIEIKAFLDSLKGAQSFQWTPPLSKSILVQAGDYQITPNGGDVWTLTVTFEQSFQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZM3</accession>
    <name>A0A2S9GZM3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Phage integrase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_2271</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93185">
        <property type="protein sequence ID" value="PRC93185"/>
        <property type="gene ID" value="S2091_2271"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044068">
        <property type="entry name" value="CB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002104">
        <property type="entry name" value="Integrase_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010998">
        <property type="entry name" value="Integrase_recombinase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00589">
        <property type="entry name" value="Phage_integrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51900">
        <property type="entry name" value="CB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51898">
        <property type="entry name" value="TYR_RECOMBINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0229">DNA integration</keyword>
    <keyword evidence="3" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="2 4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core-binding (CB)" evidence="6">
        <location>
            <begin position="45"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="domain" description="Tyr recombinase" evidence="5">
        <location>
            <begin position="176"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC93185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="398" mass="45954" checksum="D5930C777332BFD3" modified="2018-07-18" version="1">MSQEKSLLIAAMSPVTLDNVFLSTDLDGTYGSNRAVGNRSQIAANNDIEAIKAWLARFTDTKTTFDNYRKEAERLLLWSTIQQQKSLSSLTHEDLLLYQHFLEDPQPASRWIMRDSRKFARANPEWRPFAGPLSPTSQRQAIVILNTLFSWLVNAGYLAGNPLSLSRQRARKAKPRITRYLDEGLWLDVKQTIELLPKETSREREHYYRLRWLFSVLYLCGLRISEVVENNMGCFFCRRTKEGEENWWLEILGKGEKLRLVPATSELMMELARYRREKGLTPLPLAGEIHPLLLPIGEQRRQMTRGAVHAIVKQVFKDTSDRIRLRGDDCNALADRVMAASAHWLRHTAGSHMANKDVDLRHVRDNLGHESLSTTSHYLHSTDDARHRETEALHKIEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZT3</accession>
    <name>A0A2S9GZT3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">SSADH: succinate-semialdehyde dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_1948</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93210">
        <property type="protein sequence ID" value="PRC93210"/>
        <property type="gene ID" value="S2091_1948"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009013">
        <property type="term" value="F:succinate-semialdehyde dehydrogenase [NAD(P)+] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009450">
        <property type="term" value="P:gamma-aminobutyric acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010102">
        <property type="entry name" value="Succ_semiAld_DH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01780">
        <property type="entry name" value="SSADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
        <property type="entry name" value="ALDEHYDE_DEHYDR_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldedh" evidence="5">
        <location>
            <begin position="20"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="256"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC93210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="484" mass="51838" checksum="096415A45C5B865C" modified="2018-07-18" version="1">MLTLKDPSLFKQQAYLNGLWCDADNGENIAVTNPATGVTLGFVPSMGAAETRRAITAANASFKAWRSLLAKERSAILRKWYELMLVNADDLAVIMTAEQGKSLTESRGEIVYAASFLEWFAEEGKRIYGETIPTPTHGRRIMVTKEPIGVCAAITPWNFPSAMITRKAGPALAAGCPMIVKPAAQTPFSALALAELAHRAGVPAGVFSVITGKASAIGGAMTASPIVRKLTFTGSTQIGQLLMRQSADTVKKLSLELGGNAPFIVFDDADLDAAVEGALASKFRNSGQTCVCANRLYVQDKVYDAFVAKLSAAVQKLKVGDGSVAGTTQGPLIDIHAVEKVEEHIADALDKGAKIVLGGKRHALGQTFFEPTILSGVTQSMKVAREETFGPLAPIFRFHTDEEVISMANDTEFGLASYFFSRDIGRIWNVAEQLEYGMVGINTGIISNEVAPFGGVKQSGLGREGSKYGMDDYLTVKYWCISGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H028</accession>
    <name>A0A2S9H028_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 13">Biotin synthase</fullName>
            <ecNumber evidence="3 13">2.8.1.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">bioB</name>
        <name evidence="17" type="ORF">S2091_2069</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12 13">
            <text>(4R,5S)-dethiobiotin + [sulfur carrier]-SH + 2 reduced [2Fe-2S]-[ferredoxin] + 2 S-adenosyl-L-methionine = 2 5'-deoxyadenosine + [sulfur carrier]-H + biotin + 2 L-methionine + 2 oxidized [2Fe-2S]-[ferredoxin]</text>
            <dbReference type="Rhea" id="RHEA:22060"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="Rhea" id="RHEA-COMP:14737"/>
            <dbReference type="Rhea" id="RHEA-COMP:14739"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:29917"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:57586"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:64428"/>
            <dbReference type="ChEBI" id="CHEBI:149473"/>
            <dbReference type="EC" id="2.8.1.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13 14">
            <name>2Fe-2S cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49601"/>
        </cofactor>
        <text evidence="13 14">Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13 14">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="13 14">Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 13">Cofactor biosynthesis; biotin biosynthesis; biotin from 7,8-diaminononanoate: step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="13">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the radical SAM superfamily. Biotin synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.6" evidence="3 13"/>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93331">
        <property type="protein sequence ID" value="PRC93331"/>
        <property type="gene ID" value="S2091_2069"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00078">
        <property type="reaction ID" value="UER00162"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004076">
        <property type="term" value="F:biotin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009102">
        <property type="term" value="P:biotin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01694">
        <property type="entry name" value="BioB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010722">
        <property type="entry name" value="BATS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002684">
        <property type="entry name" value="Biotin_synth/BioAB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024177">
        <property type="entry name" value="Biotin_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22976">
        <property type="entry name" value="PTHR22976"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06968">
        <property type="entry name" value="BATS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001619">
        <property type="entry name" value="Biotin_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00272">
        <property type="entry name" value="biotin_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00876">
        <property type="entry name" value="BATS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00433">
        <property type="entry name" value="bioB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 13 14" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="4 13 14" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="9 13" id="KW-0093">Biotin biosynthesis</keyword>
    <keyword evidence="10 13 14" id="KW-0408">Iron</keyword>
    <keyword evidence="11 13 14" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="8 13 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 13 14" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Radical SAM core" evidence="16">
        <location>
            <begin position="61"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13 14">
        <location>
            <position position="76"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13 14">
        <location>
            <position position="80"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13 14">
        <location>
            <position position="83"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13 14">
        <location>
            <position position="120"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13 14">
        <location>
            <position position="151"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13 14">
        <location>
            <position position="211"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13 14">
        <location>
            <position position="283"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR001619-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="PRC93331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="345" mass="38017" checksum="3F3B3AFA67B9556C" modified="2018-07-18" version="1">MEQNTETSKQQGVTFHPAPKPVTPIVAETWPVDEVLGLFDLPFNELLFRAQEVHRREFPDGDVELATLLSIKTGGCEEDCGYCPQAARYDTGVEAKKILGITEVLDAARSAKESGATRFCMGAAWRSPKDRDMEKVEEMVRGVKALGLETCATLGMLKEEQAARLKDAGLDYYNHNLDTAPEFYDNVISTRDYQDRLDTLGYVRNAGLKVCCGGIVGMGESRRQRAGLIAQLANLNPYPESVPVNHLVQVEGTPLFGTEELDPLEFVRTIAVARITMPRARVRLSAGRRQMGEPVQAMCFLAGANSIFYGDKLLTTENPEASDDRVLLEKLGLRTRAKVESGGCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H050</accession>
    <name>A0A2S9H050_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ABC-type multidrug transport system ATPase component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_1984</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93246">
        <property type="protein sequence ID" value="PRC93246"/>
        <property type="gene ID" value="S2091_1984"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-1278">Translocase</keyword>
    <feature type="domain" description="ABC transporter" evidence="7">
        <location>
            <begin position="2"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="34"/>
            <end position="41"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC93246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="297" mass="32621" checksum="8726E3627C4FF769" modified="2018-07-18" version="1">MLSIKNLNKTYANGVHAINNVSLEIPNGLYGLLGPNGAGKSSLMRTIATLQEADSGSIHFNGLDVLRQGEQLRRQLGYLPQDFGVYPKVSAIDLLNHFAVLKGLTNSAERKQVVESLLQQTNLWDARKRHLGTYSGGMRQRFGIAQALLGSPKLVIVDEPTAGLDPDERNRFLNLLAEIGENVVVILSTHIVEDVTDLCPRMAMIVKGQVLVQGEPNTVIETLKSKVWRKSVSKAALAEYQKQFTVLATRLVAGQPQINVFSDHQPDDSFVAVEPDLEDVYFLHLRRSAAESVSLAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H053</accession>
    <name>A0A2S9H053_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Diguanylate cyclase DosC</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Direct oxygen-sensing cyclase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">S2091_2102</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93364">
        <property type="protein sequence ID" value="PRC93364"/>
        <property type="gene ID" value="S2091_2102"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019825">
        <property type="term" value="F:oxygen binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01948">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.490.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001633">
        <property type="entry name" value="EAL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035919">
        <property type="entry name" value="EAL_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009050">
        <property type="entry name" value="Globin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044398">
        <property type="entry name" value="Globin-sensor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012292">
        <property type="entry name" value="Globin/Proto"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00563">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11563">
        <property type="entry name" value="Protoglobin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00052">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141868">
        <property type="entry name" value="SSF141868"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46458">
        <property type="entry name" value="SSF46458"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50883">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2" id="KW-0349">Heme</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GGDEF" evidence="12">
        <location>
            <begin position="236"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="domain" description="EAL" evidence="11">
        <location>
            <begin position="378"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="10">
        <location>
            <begin position="647"/>
            <end position="762"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="764"/>
            <end position="798"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="8">
        <location>
            <position position="696"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00015125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00029839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PRC93364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="908" mass="103092" checksum="BDF896B276A0B72E" modified="2018-07-18" version="1">MPNEAISSVDEEIDTFLKAVNTTEEIQLDRFTYLEFTRSDVNAMLDLSTKLAAYKNEINNAFSSYIYCVFKDAHATDSANEKNILDEQISNFHQLINGNYDKKYVRGRIAMGLAHRKLGLPFSAYIAVYSKYNALLRPLIWSICNSNVYDLIQYMDALTKVMYFDIGIALDSYCYGDTFALSQIQHEHGHHIEQLLASTEQLLFQKNHDGLTGLPNRHSFKKQLTHLLQFAENKASTISVIKLGLDHFKIINDGEGYETGDQVLKDIGARLYGYLHKDDLVAYWGSDTFTIVLSNVEQSSDVDRICNEINEIIRAPLPINGKKIHLTCSMGIALYPQDCQNIENLITYSNSAMNQAKELGGDRYQFFNTELDARLMERITIANELYNAIENNQFCLYYQPIADLQSGQIVSMEALIRWAHPVRGLILPSQFLAIAEELSIINKLGEWIFRQVCQDIRQWQAQGIDVQPIAINISPKQLLEPLFTQNLLRTLIEQGVDPRFIILEITEGLFLHNSDAMKIILKEFKKQGFLISMDDFGTGYSALGYLKHYPFDFVKIDQSFINNITENSGNAAITNAVISMAHSMGIKVIAEGVEHEAQCQFLSKNMCDQIQGYFLSRPMPREQTADYLSKKTVLPNHLLRITKVSRTLLLVDDEPNILAALKRLFRQDGYQILTANGGLEGLEILKEKKVDVIVSDQRMPVMTGVEFLRQAKASYPETVRIVLSGYTELQSITDAINEGAIYKFLTKPWDDQQLRDQIAEAFTQKEMSDENRRLGLEIQTANQELAAANRHLAEILQLKEKQIDRDETSLDIAREALQYIPIPMLGIDEDGMIAFANIATEQILFKNTSVLGSHIDEILPRFNSIVTKMEAGKKFSLGISDFNYLANWRAMGESSKSRGKLITFFQEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0E1</accession>
    <name>A0A2S9H0E1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1810</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93423">
        <property type="protein sequence ID" value="PRC93423"/>
        <property type="gene ID" value="S2091_1810"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="659" mass="71927" checksum="8F48261EC4F1097A" modified="2018-07-18" version="1">MSYLDTPRLNFSGFFQADVSTVNNDVRYFDVDAFQESYQKIAPIPYSDTPPNGAWNPDGTGTFRLVDCKITGGRLGNRQFISPTDDPAIGMALGNADQRVSGKLVDLDPQQQMVSTIWGMQVRLSDAAQRALFEGEYEPAAFTNLWQRQQVATAPHDQQLAAIYQSVLSNVVWHGNSDSRLLESLRKATEQGYLSINMNVYGFGRDQNINRYTYGHVVGSIGPYHQQEPKRFVVGRQMIAAAPPTDPMVPSNGVSCFTCVVNAEQKTVSADFGNCLPIEGASGTFEDIGKVFLAIAKQPNDAKTGAPEIFTTLDGNSIALLGEVPYQGGQSWYEQHAGIVDMDYSKLDSWVADNINSHPLILVSPTAAQTVPPIYKVLVQESLAGLYLRADQFVYRLNPGETADVAMYSSCYGQPLATTIVTSVNTGFMGGTGGGDAPLDPPVETPVINTGSLNYPAQLNTDEHGRTILTLTAPAEGPGNPRVYIDGQLYGIGYAIKNQPDNTISNIWNLISVLAFDKIVMPEHPAWYPDIEPIFKQYANLYPIMSRHLIYLGEYESVVQNVRILDMAFALPMNNPNHMPVTRDLSEGKRNMILHWLRHPGPDGKPLKGVQAVKVATTPSSGKPIAQPVPLHLEALQTAGKTAVVLAHIANQSNKGSQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0K1</accession>
    <name>A0A2S9H0K1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_1901</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ice-binding protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93514">
        <property type="protein sequence ID" value="PRC93514"/>
        <property type="gene ID" value="S2091_1901"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1220">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014755">
        <property type="entry name" value="Cu-Rt/internalin_Ig-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021884">
        <property type="entry name" value="Ice-bd_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032812">
        <property type="entry name" value="SbsA_Ig"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13205">
        <property type="entry name" value="Big_5"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11999">
        <property type="entry name" value="Ice_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Big_5" evidence="3">
        <location>
            <begin position="53"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="domain" description="Big_5" evidence="3">
        <location>
            <begin position="166"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="domain" description="Big_5" evidence="3">
        <location>
            <begin position="295"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC93514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="664" mass="64827" checksum="F6FBCCD99379F337" modified="2018-07-18" version="1">MKRNNKNSRASSWLIALTLSVLGVVIAGCSGGSQSPILGMNGANGAGQTSAASPPTVTAVAPVNNASGVPVNNTVITSAFSEPMAPITGAASFVVSCTSPCVNPVGAVTLDATNEIASFTLANGTALAPGTTYTATVTGATSIATGLALANPYIWTFTTGAAPAVTLPGVTVTFPATSNSGPTPGVPINTAITAAFTEDMAPATINASSFTLTCTSPCAAPTGVVSYSVGSRTAVFVPNAALTVGTTYTATITTAATDLAGNALGGNQAPIPASSNYVWTFTTATTPPVPGSNVSVLSTNPAANDTSVCTNAAINATFNVPANLHMNPTTVNSATFTVTGPAPALAPVHATSVVLDAATGSIATFTPTALTAGVTYTATIHGGASGVKDLAIPADTMAANFTWNFTAVSCSAPATIPLGSASTFGNFGGSAGMTNQGIYTVVNGNIGTTAVSTSVTGFHDAGPNCIYTQTPLNVGTVNGLIYTAAPPPTVGCPSEGTATTFAVASAARADALTAYNDLVAMPAGPNPGAGNLANLTLAPGDYTAASGSFMIQGGNLTLDAQGNANATWVFQMATTLTVGGPGAAAPASIILANGAQAKNVFWQVGSAATINAGGGGTMVGTIISQDGVSISTAGNVAIVTLNGRALSLGASVTLVNTVINVPAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0K2</accession>
    <name>A0A2S9H0K2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alpha/beta hydrolase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1875</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93488">
        <property type="protein sequence ID" value="PRC93488"/>
        <property type="gene ID" value="S2091_1875"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015697258" evidence="1">
        <location>
            <begin position="35"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="domain" description="AB hydrolase-1" evidence="2">
        <location>
            <begin position="93"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="312" mass="34655" checksum="601977A92C2D6423" modified="2018-07-18" version="1">MKTKNLPIRSDNLFRTRTTIVATCALFIGAFATAAWSNPSASNSATQPLDATAPVPAITTKSISTLFEGIVVEPVHGENIEQLKINTPQSHSVVVFENGARETLETWDKVIADISKDATVFAYNRPGYGRSETTSAPRDGRTIVEELRQILQQQGLKPPYLLVGHSMGGLYMQLFARMYPQEVQGVVLVDSLYPGIIKKPEDFPLYTRIAKYLFLNNTLAHEIDEIHHTGEIIQSLPWRDDIPMVRLFNVPKSAGAIGLDFGVVNDDPQTIAMVKALYPKARQVIVDSDHRIQAENPEFVISAIREVMAIKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0L2</accession>
    <name>A0A2S9H0L2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_1894</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93507">
        <property type="protein sequence ID" value="PRC93507"/>
        <property type="gene ID" value="S2091_1894"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010559">
        <property type="entry name" value="Sig_transdc_His_kin_internal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06580">
        <property type="entry name" value="His_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="7"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="44"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="77"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="119"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="domain" description="His_kinase" evidence="3">
        <location>
            <begin position="168"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="150"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF06580"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC93507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="359" mass="41065" checksum="EE3D15132AE80A82" modified="2018-07-18" version="1">MNSRLRFWLFYWGIWALFSVYMATMDFMRHAKEHFFDVLIPMNLLQNLIWGCAGLVVLAMARRWPLARLNWTNCRNWVIHLTGSVVISMVSLWFVWLLVIVFSPPEMQQKVLADPLSNYYGFFSMYFHINLLLMWAVLGAYHGARILGLSRKQELEAAQLQSRLAIAQNRALQMQLQPHFLFNTLNSIAALIHSDQEAADKMLTRLADLLRMTLDSGSANEISLRQEMAFTDTYLSIEAIRFQDRLTIQRDVPFDCMDALVPAFLLQPLVENAVKHGVANLARSATITIRAHHDDEWLILDVIDNGCGINGNSKRGIGTRNTATRLQLMYQNRHAFDMTNLPGGGAQVTVRIPWRTQPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0P7</accession>
    <name>A0A2S9H0P7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">O-antigen ligase like membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_1907</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93520">
        <property type="protein sequence ID" value="PRC93520"/>
        <property type="gene ID" value="S2091_1907"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007016">
        <property type="entry name" value="O-antigen_ligase-related"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04932">
        <property type="entry name" value="Wzy_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="2 3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="48"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="90"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="130"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="155"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="196"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="228"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="252"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="281"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="525"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="551"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="576"/>
            <end position="592"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC93520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="598" mass="67720" checksum="121405DB3F691F55" modified="2018-07-18" version="1">MLSSLSIHPIALWLLLIYGGYVLFLWRWPQTWLPILLAALPVLDFAPWTGQFFFDEFDLLLLLTVITVLARRGLGELKNTYFGMTTTATALFWAVGLAGLVATIMGAWPFPALDSNSFNNYYSPYNALRVGKGLGFALLLLPLLAGDLQRDADKTFYRIAFGMSLGVLGAGLAVAWERISMTGLWNFHSGYRVVGLFSGMHTGGAYIEAYFATAMPFVLWWGIHSRHWALKLSASLIFLIACYAMLVTYARGGYLALILASIVLLAGMLPHRSVMQRMRHIFITMLVLLLIGVGLWFSLINTPMHWRAGNMQRDMNLRVAHWHQILDIMDQGLPVKLFGMGQGRLPGLYVQRVPAANISEYRFMREDEHNYLHLTGGDPLYFEQVVDVQPDKLYILKIVVRSKDPNAELYLPLCQKWMLYPEQCLWKVVKPGDATDWQTFTLSIDTKQLRDQSWHSRAPRKLSLVNFNDGSVIDIASVSLRAPNGDELIANGDFAQGMQNWFFSTENHLPWHFKNLALQLYFEQGWFGLILMSALLIYSAVILVRRADEKAFPAALLASALIGFLTVGMVDSLFDFPRMSIVFYLLVLLIHLREKIES</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0Q1</accession>
    <name>A0A2S9H0Q1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1548</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93547">
        <property type="protein sequence ID" value="PRC93547"/>
        <property type="gene ID" value="S2091_1548"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03360">
        <property type="entry name" value="LbH_AT_putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020019">
        <property type="entry name" value="Sia_OAcTrfase_NeuD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14602">
        <property type="entry name" value="Hexapep_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03570">
        <property type="entry name" value="NeuD_NnaD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="212"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="231" mass="24679" checksum="1119ADE2F46FFDAA" modified="2018-07-18" version="1">MKKIVFGLIGAGGSGREVMPFVKSSICKTLSVPPGIIHVYFVETWEPENSKVNGYPLISLDDFFALDGDKYFNIAIGDGRAREAMFTMVAGKAEVIEIHSPRADFLENNSIGIGSVFCPNSMITSDVKIGKFFQANIFSSVSHDCVIGDFVTLSPGARCNGRVIVGDYAFIGANAVIKEGKIDKPLRIGKGAVVGMGAVVTKDVPDGVTVVGNPARPIKKNKPLESENNSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0Q6</accession>
    <name>A0A2S9H0Q6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1565</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93564">
        <property type="protein sequence ID" value="PRC93564"/>
        <property type="gene ID" value="S2091_1565"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.115.10.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023296">
        <property type="entry name" value="Glyco_hydro_beta-prop_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75005">
        <property type="entry name" value="SSF75005"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="311" mass="35378" checksum="71EF5DA5DFE7C83B" modified="2018-07-18" version="1">MSTKWQKLGLLYCPSEIGQHPKLLSHASNPLPVLIDGDVYRVFFSGRDADNRSSVGAVDVDVVKHKIVQVHRQPFFEHGQEGSFFADGVSIGNCYEIDGKRYMLFMGWQNPFNRHWRGDIGRLIVNSDLTLELDSDTPFMSLDEVDPISLSYPWVLRNENGGYNMWYGSTTTWDAGNKEMLHVINYASSSDGNHWEREGLAVPYELGTAQAFSRPTVAYYAQGYEMWFSYRSGSDMKYRIGYANSKNSKEWKLRLEEAGINVSAAGWDSEMIEYPFVFKHKGIRYMLYNGNSYGKTGFGLAIEEDEHGASK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H110</accession>
    <name>A0A2S9H110_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1676</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93675">
        <property type="protein sequence ID" value="PRC93675"/>
        <property type="gene ID" value="S2091_1676"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022742">
        <property type="entry name" value="Hydrolase_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022744">
        <property type="entry name" value="MeTrfase_dom_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12146">
        <property type="entry name" value="Hydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12147">
        <property type="entry name" value="Methyltransf_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Hydrolase_4" evidence="1">
        <location>
            <begin position="43"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="domain" description="Methyltransf_20" evidence="2">
        <location>
            <begin position="286"/>
            <end position="591"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="597" mass="66696" checksum="6C49307E4196B310" modified="2018-07-18" version="1">MTTLATSSSAAWLNSESGFDSADQTRLFYRCWQPIAKRAEGAQRALIFLHRGHEHSGRIQPLVEQFGFQQDWAFAWDARGHGYSPGERGDAPSFELLVQDFNAFIAYIQQTYHIEPENMLIVANSVGAVIAATWLHDYAPKVRGVIMAAAAFEIKLYIPFAKAGLRLATCFKPDLFVTSYIRSSMLTHSKQQAAQYDQDPLIAKSISARVLLGLADTAKRIVHDASAIDVPVLMLAAENDYVVALTPQRQFFDRLASPLKRFELIKNCFHAIFYEQEVEQAMQASRQFINDCFELPAAPVQQHHKADSHSASAQQFQALQQGELGSPLLNMFYGMQKMMLGVLGPLSDGMKIGLTHGFDSGSSLDYVYRNQAGGRLGIGKSIDRGYLDAIGWRGIRQRKIHLQQALSKLIAQHPQDQPLRILDIAAGGGRYVLETIKRFQDREIQLTLRDFVPENLEQAKQLATHLHLTTPIQYQCRDAFSSDSYPESELPYDIVIVSGLYELFSENAPIMRSLQGIRQQLKKGGHVIYTGQPWHPQLLLIAKTLNNHLGESWQMRPRPQVEMDALVAAIGCRKVHTQIGISGIFTVSVAQFGGAVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1B4</accession>
    <name>A0A2S9H1B4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1741</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93740">
        <property type="protein sequence ID" value="PRC93740"/>
        <property type="gene ID" value="S2091_1741"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="59" mass="6982" checksum="E4DC83D59023E4FD" modified="2018-07-18" version="1">MHMRLLLSLLLIMLAHLKIDVILFAKMVFQFHKLHDKSISICHFVSLFSCIIPTLKFER</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1C0</accession>
    <name>A0A2S9H1C0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fimbrial protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1388</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93779">
        <property type="protein sequence ID" value="PRC93779"/>
        <property type="gene ID" value="S2091_1388"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009289">
        <property type="term" value="C:pilus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007155">
        <property type="term" value="P:cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1090">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000259">
        <property type="entry name" value="Adhesion_dom_fimbrial"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036937">
        <property type="entry name" value="Adhesion_dom_fimbrial_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008966">
        <property type="entry name" value="Adhesion_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00419">
        <property type="entry name" value="Fimbrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49401">
        <property type="entry name" value="SSF49401"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015622817" evidence="1">
        <location>
            <begin position="25"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="domain" description="Fimbrial" evidence="2">
        <location>
            <begin position="193"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="337" mass="35911" checksum="3ED3A3393D6BAC72" modified="2018-07-18" version="1">MIKFSAVLNFTLCTLLFYVSNAQADRGCTVTQNTFNMPISLSVAQDHPINTPIGAAGTYDLYSCSDTSQFNQAITISSYDSTGKRINGRLIFNSGIKGIGYSVGMKSIGNCDGKIDYAGRESNNWPYTVLCRAKGLFPVQPIKGQFLLTFYKIAPTTDSGTVASKTSITAPLYNNDGWWTSPESKLTITGLTVTTVSCSMPNVTVPMGKTNTLQMFDGVGSRLSPVPFEIRLNNCIAGPNTSVKYQFDPLKPALDSKNGILALDSGGAKPAATGVGIQIRSADGNEAVQEFGVPHAFGNITTGGSYTIPFNARYIQTAAKVAAGIANSAMTFTLIYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1F3</accession>
    <name>A0A2S9H1F3_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">4-diphosphocytidyl-2-C-methyl-D-erythritol kinase</fullName>
            <shortName evidence="9">CMK</shortName>
            <ecNumber evidence="2 9">2.7.1.148</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8 9">4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">ispE</name>
        <name evidence="12" type="ORF">S2091_1382</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>4-CDP-2-C-methyl-D-erythritol + ATP = 4-CDP-2-C-methyl-D-erythritol 2-phosphate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18437"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57823"/>
            <dbReference type="ChEBI" id="CHEBI:57919"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.148"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="9">Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via DXP pathway; isopentenyl diphosphate from 1-deoxy-D-xylulose 5-phosphate: step 3/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the GHMP kinase family. IspE subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.148" evidence="2 9"/>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93773">
        <property type="protein sequence ID" value="PRC93773"/>
        <property type="gene ID" value="S2091_1382"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00056">
        <property type="reaction ID" value="UER00094"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050515">
        <property type="term" value="F:4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019288">
        <property type="term" value="P:isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016114">
        <property type="term" value="P:terpenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.890">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00061">
        <property type="entry name" value="IspE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013750">
        <property type="entry name" value="GHMP_kinase_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036554">
        <property type="entry name" value="GHMP_kinase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006204">
        <property type="entry name" value="GHMP_kinase_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004424">
        <property type="entry name" value="IspE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43527:SF2">
        <property type="entry name" value="PTHR43527:SF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08544">
        <property type="entry name" value="GHMP_kinases_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00288">
        <property type="entry name" value="GHMP_kinases_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF010376">
        <property type="entry name" value="IspE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55060">
        <property type="entry name" value="SSF55060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00154">
        <property type="entry name" value="ispE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 9" id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword evidence="5 9 12" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GHMP_kinases_N" evidence="10">
        <location>
            <begin position="90"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="domain" description="GHMP_kinases_C" evidence="11">
        <location>
            <begin position="207"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="14"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="139"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="97"/>
            <end position="107"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00032554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF08544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PRC93773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="287" mass="31320" checksum="9252EA60FDB4FF5D" modified="2018-07-18" version="1">MTVSSLKNCPAPAKLNLFLHVTGQRSDGYHLLESAFQLIDHVDLLHFSLRDDAKIIRTNELAGVPAETDLVVRAARLLQVHTSSKLGAEITLDKKLPMGGGLGGGSSDAATTLIALNRLWETDLSRQQLMQLGLQLGADVPFFLFGQNAFAQGIGEKLTPLITPDCWYVVIEPGVSVPTQAIFSSKALTRNSSSIKVSDFQQYPKGNWRNDLQSVAIQLFPEILVAIDWLNKYGNARMTGSGSCVFCACSSEDAANEILKDIPGELQDWTAWKAKALNEHPLTNWLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1I4</accession>
    <name>A0A2S9H1I4_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_1448</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93839">
        <property type="protein sequence ID" value="PRC93839"/>
        <property type="gene ID" value="S2091_1448"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013655">
        <property type="entry name" value="PAS_fold_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08447">
        <property type="entry name" value="PAS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="40"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="72"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="6">
        <location>
            <begin position="127"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="7">
        <location>
            <begin position="203"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="5">
        <location>
            <begin position="259"/>
            <end position="478"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC93839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="486" mass="54319" checksum="D17502ABA9D80833" modified="2018-07-18" version="1">MKNNPAQSEHLADGMSADVDAKLNANPPWQVRHLVTHKNFPVLVSFAAFFAVTLLGWLLLSRIVTLSNSAESTGLVLTLVVFVVGASISLLLFLLMSTNLQQRDRALGMAHAMTEEIRLQSEKLSFSQERFELAIRGANDGLWDRDLVQGTAYYSPRWKSMLGYSENELPSSQEEWMKRVHPEDLAFILRKEKLCLDGKIERFQNEYRLRHKNGSYIWILDRGLILFNANGTATRFIGVISDISEQKRLEKLKSEFISTVSHELRTPLTSIAASLGLLEAGVFGELPSKALGLVNIASKNSKRLTTLVNDILDMEKLLSGKTVFRTDEIDLVELIKQSMELNAEFASSFGVNFTLSSSTGFRSVIGDKDRLLQVMANLMSNATKFSHFGGSVEIRLVQQDRCVRVEIEDRGAGIPVDFRHRMFGEFAQADSSDTRQQGGTGLGLNITKKLVERMGGEIGYISEFGQGSTFWFTMPSTSSWHFSVKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1J3</accession>
    <name>A0A2S9H1J3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Pro-kumamolisin, activation domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">S2091_1737</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93736">
        <property type="protein sequence ID" value="PRC93736"/>
        <property type="gene ID" value="S2091_1737"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04056">
        <property type="entry name" value="Peptidases_S53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11377">
        <property type="entry name" value="Pro-peptidase_S53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015366">
        <property type="entry name" value="S53_propep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030400">
        <property type="entry name" value="Sedolisin_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09286">
        <property type="entry name" value="Pro-kuma_activ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00944">
        <property type="entry name" value="Pro-kuma_activ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="SSF52743"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51695">
        <property type="entry name" value="SEDOLISIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0106">Calcium</keyword>
    <keyword evidence="4 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 7" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0720">Serine protease</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015711402" evidence="9">
        <location>
            <begin position="42"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S53" evidence="10">
        <location>
            <begin position="238"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="399"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="402"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="7">
        <location>
            <position position="309"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="7">
        <location>
            <position position="313"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="7">
        <location>
            <position position="534"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC93736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="633" mass="64900" checksum="31C7652E792E9A57" modified="2018-07-18" version="1">MKFSSNFNLQSNASAGEFVLPRISSLALAISLACGVMGAQAAVDTSSWVPTKTEAFLAKVHTHDSTGAEVTADQIAVEMAQGEQKSVTVSLQLRNQAQLESFLTALHTPGNASYHKFLTPAQFAAQYSPTQAQVDAVVAHLTSAGFKNISVSSNRTLVSADGTAATVKQAFNTSLKRFTHEGRSVYANDKPAQIPAALADIVGSVLGLQNAAIHHATHSGVHTAAKSGTQAATGTEVAHIPTQYPGIYNAVTTPAASTAIVGTIAEGNMTYTLQDFATFLSNNPSLPKLTPTVVYVGGENTTDESGEVEWALDSQVIYGAAGGVKQLIFYTANSMEDAALTAAYNAAVTANVASVVNVSLGECEASAKSSGSQAADDAVFKQAVAQGITFSVAAGDAGPYNCDTDSQGNPGVAKTTTQKKTYDVSEPASSPYVVAVGGTALFTTSTGAYAGQAVWNEGSASTGDGSAVRIWSTGGGFSKNELAPAWQTASIVGSGHTYRGLPDIVFDAAQASGTNIYINQAANGTAYAAVGGTSMAAPMFAGFWARLESAHGNNLGFPNSAFYKAIPANPGLVFPVTSATVDGDSIEYNGWSTTYPGMSAAASGWSAATGFGSLNIDAVNAYITANPTVFPPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1S5</accession>
    <name>A0A2S9H1S5_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 12">Anthranilate synthase component 1</fullName>
            <ecNumber evidence="6 12">4.1.3.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">trpE</name>
        <name evidence="15" type="ORF">S2091_1114</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>chorismate + L-glutamine = anthranilate + H(+) + L-glutamate + pyruvate</text>
            <dbReference type="Rhea" id="RHEA:21732"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16567"/>
            <dbReference type="ChEBI" id="CHEBI:29748"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="EC" id="4.1.3.27"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 12">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 12">Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 1/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5 12">Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 12">Belongs to the anthranilate synthase component I family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.3.27" evidence="6 12"/>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC93941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93941">
        <property type="protein sequence ID" value="PRC93941"/>
        <property type="gene ID" value="S2091_1114"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00035">
        <property type="reaction ID" value="UER00040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004049">
        <property type="term" value="F:anthranilate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000162">
        <property type="term" value="P:tryptophan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005801">
        <property type="entry name" value="ADC_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019999">
        <property type="entry name" value="Anth_synth_I-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006805">
        <property type="entry name" value="Anth_synth_I_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005256">
        <property type="entry name" value="Anth_synth_I_PabB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015890">
        <property type="entry name" value="Chorismate_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11236">
        <property type="entry name" value="PTHR11236"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04715">
        <property type="entry name" value="Anth_synt_I_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00425">
        <property type="entry name" value="Chorismate_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00095">
        <property type="entry name" value="ANTSNTHASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56322">
        <property type="entry name" value="SSF56322"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00564">
        <property type="entry name" value="trpE_most"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 12" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="10 12" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="11 12" id="KW-0456">Lyase</keyword>
    <keyword evidence="12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 12" id="KW-0822">Tryptophan biosynthesis</keyword>
    <feature type="domain" description="Anth_synt_I_N" evidence="14">
        <location>
            <begin position="26"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="domain" description="Chorismate_bind" evidence="13">
        <location>
            <begin position="221"/>
            <end position="479"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00020653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU364045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF04715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="PRC93941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="498" mass="55037" checksum="211CC40D2BF20E01" modified="2018-07-18" version="1">MTEIEFHSLANQGYNRIPLIIEAFADLETPLSVYLKLAQSQHGGKNTFLLESVVRGERLGRYSFIGLPANTSLRCYHERCEVLQDGKVIESHTGNPLEFIAAFQARYKVALRPGLPRFCGGLAGYFGYDTVRHIETRLAHSCPKDDLGLPDIQLLVTEELAVIDNLSGKLYLIVYADPSKPEAFSKARVRLKELRAMLRRSVDAPVTSASVRTETIREFAKEDYLKAVTRAQEYIMAGDLMQVQIGQRIKKPYVDSPLSLYRALRSLNPSPYMYFYNFGDMHIIGSSPEILVRNEGQEDGSHTVTIRPLAGTKPRGTTPAQDEQLAKELLADPKEIAEHVMLIDLARNDLGRIAKTGTVRVSDQMAIEKYSHVQHIVSNVEATLQDNLSNLDVLKATFPAGTLSGAPKVRAMEIIDELELTKRGIYGGACGYLSFSGAMDLAIAIRTGVLKDGMLYVQAAAGIVADSVPDSEWQETENKARAVLRAAEHVQDGLDGEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1S8</accession>
    <name>A0A2S9H1S8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Surface presentation of antigens (SPOA)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1527</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93918">
        <property type="protein sequence ID" value="PRC93918"/>
        <property type="gene ID" value="S2091_1527"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.330.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001543">
        <property type="entry name" value="FliN-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036429">
        <property type="entry name" value="SpoA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01052">
        <property type="entry name" value="FliMN_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101801">
        <property type="entry name" value="SSF101801"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FliMN_C" evidence="1">
        <location>
            <begin position="190"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="262" mass="28758" checksum="1CEA20911BE61FA2" modified="2018-07-18" version="1">MATHTFALLKQRDINSCIERACDAVSEWESAWCPSSGIEIDCSETCDPSVIQPGGLWTAHRLTQGSLVWCYCPTEFGKQAERLIFDLNDALRSTDRHRESALAENVANEAVDELVALLLNRLAGPTTAQLEFGTKPADWQFRRHSGTALIKITIGGKTLSLLIPSERLPSHEIARKSPPREAVTPLPVALNKIEVRLIAELGDVEMSLGHFASLQLGDVINLSIGIDQSLTVFTENRCPVGVAHLGKQDGNRALEMFKIPHN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1W2</accession>
    <name>A0A2S9H1W2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1148</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC93975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93975">
        <property type="protein sequence ID" value="PRC93975"/>
        <property type="gene ID" value="S2091_1148"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041492">
        <property type="entry name" value="HAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13419">
        <property type="entry name" value="HAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01549">
        <property type="entry name" value="HAD-SF-IA-v1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="248" mass="28319" checksum="F860C7F0DB5A58E9" modified="2018-07-18" version="1">MKINNKERFTRLPDAFLFDTDNTLYPYDPAHAAAQKAVRDKVVSTFSISPEDFDKAFKEARNQIKTRLKHTASSHSRLLYLQRMLEIMGLGSQVLLALDFEQTYWRTFLSNAILFDEVKGLLDDIRLLGIPTAIVTDLTAQIQFRKVVYFGLDNYFDYIVTSEEAGFDKPHEAPFQIALEKMRPKGDCIWMIGDNPVNDIRGARENINAVTLQKTHPGVQLGTDANRPDASFNEFSQLRKLITKLAEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1X1</accession>
    <name>A0A2S9H1X1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1154</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC93981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93981">
        <property type="protein sequence ID" value="PRC93981"/>
        <property type="gene ID" value="S2091_1154"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="56" mass="5965" checksum="164E9844B3E3DD1C" modified="2018-07-18" version="1">MHDQSIQNEVILGVDTHLDTHVAAVISHTGKLLGTLATPTDANGYLKLLAWARSLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1Y5</accession>
    <name>A0A2S9H1Y5_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Phosphoribosyl-AMP cyclohydrolase</fullName>
            <shortName evidence="7">PRA-CH</shortName>
            <ecNumber evidence="7">3.5.4.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">hisI</name>
        <name evidence="9" type="ORF">S2091_1174</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>1-(5-phospho-beta-D-ribosyl)-5'-AMP + H2O = 1-(5-phospho-beta-D-ribosyl)-5-[(5-phospho-beta-D-ribosylamino)methylideneamino]imidazole-4-carboxamide</text>
            <dbReference type="Rhea" id="RHEA:20049"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:58435"/>
            <dbReference type="ChEBI" id="CHEBI:59457"/>
            <dbReference type="EC" id="3.5.4.19"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="7">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="7">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 3/9.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the PRA-CH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.19" evidence="7"/>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94001">
        <property type="protein sequence ID" value="PRC94001"/>
        <property type="gene ID" value="S2091_1174"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00008"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004635">
        <property type="term" value="F:phosphoribosyl-AMP cyclohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.810">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01021">
        <property type="entry name" value="HisI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026660">
        <property type="entry name" value="PRA-CH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002496">
        <property type="entry name" value="PRib_AMP_CycHydrolase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038019">
        <property type="entry name" value="PRib_AMP_CycHydrolase_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01502">
        <property type="entry name" value="PRA-CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141734">
        <property type="entry name" value="SSF141734"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="3 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 7" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="5 7 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="PRA-CH" evidence="8">
        <location>
            <begin position="39"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="86"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="87"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="88"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="90"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="104"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="111"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC94001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="138" mass="15711" checksum="8D24386739E57EC6" modified="2018-07-18" version="1">MITKHSAKSSSKWLNKVQWDEHGLVPVIAQQTGTNDVLMFAWMNRDALEKTVELGEAVYWSRSRKKLWHKGEQSGHIQKVLDIRLDCDSDVVLLKVEQVDDIACHTGRHSCFFQQLNVAEAEWQAVEPVLTDPEAVGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1Z3</accession>
    <name>A0A2S9H1Z3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1150</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC93977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93977">
        <property type="protein sequence ID" value="PRC93977"/>
        <property type="gene ID" value="S2091_1150"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="115"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="165"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="196"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="225"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="287"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="315"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="356"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="386"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="583" mass="64496" checksum="D8680B8436F6CCB2" modified="2018-07-18" version="1">MIKKIIAYPKNIRNRLFEMSIPASNEPMQSNLCPTILFSLTIFFYILYQLAMQPGWVLGGEMWAEMATNYFPNANSPSYLQKLFSTDSGYIPAPQRLIAFVGNQLNLPAASVPYFYTWSAIIFTAMMVGTFCLAQFRILVKSDLLRFLTAISILMVADFETRTFINFTYFSAFFVAIVTALALVDDSEDIPWWAWFVPILMVSKPAVLAALPAMILVAMVSKSRFRWITIIVVALCIGQILQMVTSAQTGMMPFRINEITFASKVIASFRYFLGFLGGYVIGQTPQLTTYFLMLAGLFVVSVSGFAIFNRKSKAGALIIIGLSLLFFNVLLNAFALSDLWNLDMTRLDGIPVYRHIVVGFSGCIMVASGLFSALTHQKTSKPSGHFRKNLGALLFFVWFTGSGWLSFAGKISREPRSPTINNSQWQNMAVAIDSGISPVCVPIDPWWKGTSWMYQRNCSVLKPAPAWEDGLVLISNPLFFDLTPPSAISDKTLIAAAILVKPFSTQKAFIEVQMLIKLVDGNVMYYAGARNLNSSGGLLLLTGKESIAIKNISSVRLIFNVPVEIALAANDPTGVPGIAWMGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H238</accession>
    <name>A0A2S9H238_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="16">Conserved region in glutamate synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">S2091_1193</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>[3Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:21137"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="14">Amino-acid biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glutamate synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94020">
        <property type="protein sequence ID" value="PRC94020"/>
        <property type="gene ID" value="S2091_1193"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00705"/>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051538">
        <property type="term" value="F:3 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015930">
        <property type="term" value="F:glutamate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006537">
        <property type="term" value="P:glutamate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00982">
        <property type="entry name" value="gltB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02808">
        <property type="entry name" value="GltS_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002489">
        <property type="entry name" value="Glu_synth_asu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036485">
        <property type="entry name" value="Glu_synth_asu_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006982">
        <property type="entry name" value="Glu_synth_centr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002932">
        <property type="entry name" value="Glu_synthdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00310">
        <property type="entry name" value="GATase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04898">
        <property type="entry name" value="Glu_syn_central"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01645">
        <property type="entry name" value="Glu_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01493">
        <property type="entry name" value="GXGXG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69336">
        <property type="entry name" value="SSF69336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0003">3Fe-4S</keyword>
    <keyword evidence="4" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-0288">FMN</keyword>
    <keyword evidence="12" id="KW-0314">Glutamate biosynthesis</keyword>
    <keyword evidence="8" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="11" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="15">
        <location>
            <begin position="16"/>
            <end position="416"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00029440"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="PRC94020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="1552" mass="169416" checksum="6AEDBAA308090B46" modified="2018-07-18" version="1">MQAQGLYDPKNEHDACGVGFVAHIKGNKSHMIVEQGLLILQNLDHRGAVGADELMGDGAGILLQLPDQFFREEMALQNVILPPPGEYGVGMVFLPKEHASRLACEQEIERSVRIEGQIVLGWRDVPVDKSMPMSPTVRDKEPVIRQIFIGRGPDIMVTDALERKLYVIRKSAVHAIEALHLIHGKEYFVPSMSARTIVYKGLLLATQVGVYYQDLQDPRFISALALVHQRFSTNTFPEWPLAHPYRMIAHNGEINTVKGNFNWMRAREGVMSSAVLGNDLQKLYPLIFEGQSDTACFDNALELLVMAGYPIAQAMMMMIPEAWENHTMMDDNRRAFYEYHAAMMEPWDGPAAMAFTDGRQIGGTLDRNGLRPARYIITDDDLVVMASESGVLPIPESKIIKKWRLQPGKMFLIDLDAGRIIDDQEIKNTYANAKPYKQWINSVRIKLNKLPEAAALASSDVALLDRQQAFGYTQEDIKFLMTPMAESGEEAIGSMGNDSPLAITSNKNKTLYNYFKQLFAQVTNPPIDPIREAMVMSLVSFIGPKPNLLDTNNINPPMRLEVAQPVLNFADMARLRNISEYTGGKFKSYDLNICYPVVWGKEGIEARLASICAEVVDAVKSGHNIIIISDRKMDADTVAIPALLATSTVHQHLVSRGLRTITGLVVDTGSARETHHFALLAGYGAEAVHPYLAMESLQVMAAELKLSADEAIYNYTKAIGKGLMKVMSKMGISTYMSYCGAEIFEAVGLSKALVSKYFRGTASNVEGIGLFDVAEEALLLHKQAFGADPVLANALDAGGEYAFRIRGEDHMWTPDAIAKLQHSTRSNNFNSYKEYAQIINDQSKRHMTLRGLFEFKIDPTKAIPLDQVESAKEIVKRFATGAMSLGSISTEAHTTLAVAMNRIGGKSNTGEGGEDPARYQQELKGIPIKQGETMASILGAEQIKVDIPLLDGDSLRSRIKQVASGRFGVTAEYLNSADQIQIKMAQGAKPGEGGQLPGHKVSEYIAKLRFSVPGVGLISPPPHHDIYSIEDLAQLIHDLKNANPKASISVKLVSEVGVGTVATGVTKAKADHIVIAGHDGGTGASPLSSVKHAGTPWELGLSETQQTLVLNGLRGRVRVQADGQMKTGRDVAIAAMLGADEIGFATAPLVVEGCIMMRKCHLNTCPVGVATQDPLLRAKFAGKPEYVVNYFFFVAEEVRQIMAQLGLRSFDEMIGRVDLLDKSKAITHWKAQGLDFSKIFHQIEKDSPIRHVDVQDHGLEKALDHKLIAQAQIALTTGEKVSFISSVKNVNRTVGTMLSGLVARQFGHDGLPDDTIHIQLQGTAGQSFAAFLAHGITLDLVGEGNDYVGKGLSGGRVILRPNTEFRGRAVDNIICGNTVLYGAIAGEAFINGVAGERFAVRNSGATTVVEGTGDHGCEYMTGGTVVVLGDTGRNFAAGMSGGLAYVYDEHGDFAAKCNLSMVTLEPVLSGIEQQAHSGVLYHSVLRGGIGETDEAILRNLIERHFKHTGSTRARNLLDDWARSRAKFVKVFPTEYQRALAEMQAAKLTQKAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2A8</accession>
    <name>A0A2S9H2A8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">PPIC-type PPIASE domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_1271</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94098">
        <property type="protein sequence ID" value="PRC94098"/>
        <property type="gene ID" value="S2091_1271"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000297">
        <property type="entry name" value="PPIase_PpiC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027304">
        <property type="entry name" value="Trigger_fact/SurA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00639">
        <property type="entry name" value="Rotamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109998">
        <property type="entry name" value="SSF109998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50198">
        <property type="entry name" value="PPIC_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0697">Rotamase</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015456103" evidence="3">
        <location>
            <begin position="20"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="domain" description="PpiC" evidence="4">
        <location>
            <begin position="146"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="294"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC94098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="320" mass="33821" checksum="4F7626CC01A09AF2" modified="2018-07-18" version="1">MLIKSRVVLGSAVALMALAACTPKEADKTAAAATSATPAKEVVAATVNGTPISQKQVDMILHQQRGMPDTPETRKMIIDNIAMQLIVAQEAVKKGLDKTADTMDEIEMAKQSVLAQAFVQDYIKHNEVTDAQLATEYDKLKAQASGNQFKARHILVKTEDEAKAIIAKLNKDPKSFEAIAKAQSLDPGSKVKGGDLGWFDAHSMVPEFGAAVAKLEKGKFTEEPVKSQFGYHVIMLDDTRPSTATIPPLEQVKAGLSQQLQQQNLKKMLDDMKAKAKIDIVAAAPAPAAVVPAPAAPAADAVPAAAAPAASTPAAEPAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2D9</accession>
    <name>A0A2S9H2D9_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peptidase S53 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_1286</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94113">
        <property type="protein sequence ID" value="PRC94113"/>
        <property type="gene ID" value="S2091_1286"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04056">
        <property type="entry name" value="Peptidases_S53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030400">
        <property type="entry name" value="Sedolisin_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="SSF52743"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51695">
        <property type="entry name" value="SEDOLISIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 4" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="Peptidase S53" evidence="5">
        <location>
            <begin position="387"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="4">
        <location>
            <position position="464"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="4">
        <location>
            <position position="468"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="4">
        <location>
            <position position="662"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC94113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="755" mass="79106" checksum="185C0BBFF3A06AED" modified="2018-07-18" version="1">MKEQFRMLKINFETMTPTKWLIVLASVVTLSACGGHSSSGGINVANAVLSKNQQIFESLEFSGGTYSVDWSFPYGGGNLVNGANYIASNSTGGLSKSPAIEGAQTQLPVVTSLDVNLQAPTFGPAVYLNGGQVITRSATAQRKVSYVGSNIQVDYIADDGVTVAQSTQFSNFSSVPLTGFMGSTANEFQASVPINNWISANNFSANAKWQPGSVYTKRQGTSVGDTYYVQNCQNFSNVVVTTATTSTVVCQAGGTIAQIFPIVQFDEGSGHPTEEEAYSDGTMTTVQGLPMWIANNPIPTTLLYRTYFQLDGNIYMGYMHKSGVAYHYDMNDGTTTDYLISMNQAAVNSIQQGIITGASVTGSQSGNTNSVSSIDLFGLGAHGINGALAPVDLLSHYNVPANLNGAGQTIVIIDAPGSANVLDDLNTYSQFFNLPQCNSANPCFQQIDLSNGAAVDPNNDWGIEVELDTQMVHAIAPQAKIILITANSSSSTDLSAAITYAASLPNVTAVTMSFGGSDNPPIVSATQIEPAEYLAEDTAFATAQANLGMIFFASSGDSGNYFYTTPGGFAYPASSPYVTAVGGTQINSLNWGLGSQSEIGWQFSGGGTSTGFALPNWQASYPAIASNNAYRAVPDVSAVADGQHSALSIYYKQQWVMVGGTSASSPIWAGFSALFGQYLGNKGQSLSTLIKNTSGGFNGLLYQSRITQGSNPGLTNITAGSNGFDLGCSVCSAGVGYNDVTGLGVPNMTNFLANF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2F8</accession>
    <name>A0A2S9H2F8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major Facilitator Superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_1337</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94164">
        <property type="protein sequence ID" value="PRC94164"/>
        <property type="gene ID" value="S2091_1337"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001958">
        <property type="entry name" value="Tet-R_TetA/multi-R_MdtG"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01035">
        <property type="entry name" value="TCRTETA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="15"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="49"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="82"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="104"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="139"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="168"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="220"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="257"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="287"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="310"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="344"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="378"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="12"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC94164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="409" mass="44024" checksum="24FC0EE97FC3A040" modified="2018-07-18" version="1">MSSEVKPPSLINSRFVLITVFLDILGIGLIIPVLPRMVAMFAPQPDQQAYWYGAIVAAYAIMQFFCAPLLGALSDRFGRRPILLICVLGLGLNFFLMTQAPSLIWLLVIRAMGGMTAGNIAVANAYIADVSKPENRGKALGKIGAMFGMGFICGPMLGGLLGEQHYQYPFYLAAIVSLCNFSYGLVALPESLPLNNRRAFSFTRANPLHNLKGLTQLKNVGALVWSMGFSLFAQFTMQTTWVLSTELRFGWTPLQNGISLFMVGVCSVVMQGFLLGGVIRRLGEAKTAMWGLSSSCLVLIMYGVTQQGWIMYLLIPCNILGYAAAPAIQAIFSKAVDAKSQGAVMGSLSSLGSVMSVCATLLGTSLLAQVGHFPKGNILLGAPFFMAAFAQGMALLIAMKHFSNVKKLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2M5</accession>
    <name>A0A2S9H2M5_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glucose-6-phosphate isomerase</fullName>
            <shortName evidence="7">GPI</shortName>
            <ecNumber evidence="7">5.3.1.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Phosphoglucose isomerase</fullName>
            <shortName evidence="7">PGI</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Phosphohexose isomerase</fullName>
            <shortName evidence="7">PHI</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">pgi</name>
        <name evidence="9" type="ORF">S2091_0814</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7 8">
            <text>alpha-D-glucose 6-phosphate = beta-D-fructose 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:11816"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="ChEBI" id="CHEBI:58225"/>
            <dbReference type="EC" id="5.3.1.9"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Carbohydrate biosynthesis; gluconeogenesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 7 8">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7 8">Belongs to the GPI family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.9" evidence="7"/>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94193">
        <property type="protein sequence ID" value="PRC94193"/>
        <property type="gene ID" value="S2091_0814"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00181"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00138"/>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097367">
        <property type="term" value="F:carbohydrate derivative binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004347">
        <property type="term" value="F:glucose-6-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd05015">
        <property type="entry name" value="SIS_PGI_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05016">
        <property type="entry name" value="SIS_PGI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00473">
        <property type="entry name" value="G6P_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001672">
        <property type="entry name" value="G6P_Isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023096">
        <property type="entry name" value="G6P_Isomerase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018189">
        <property type="entry name" value="Phosphoglucose_isomerase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046348">
        <property type="entry name" value="SIS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035476">
        <property type="entry name" value="SIS_PGI_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035482">
        <property type="entry name" value="SIS_PGI_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11469">
        <property type="entry name" value="PTHR11469"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00342">
        <property type="entry name" value="PGI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00662">
        <property type="entry name" value="G6PISOMERASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53697">
        <property type="entry name" value="SSF53697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00765">
        <property type="entry name" value="P_GLUCOSE_ISOMERASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51463">
        <property type="entry name" value="P_GLUCOSE_ISOMERASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 7 8" id="KW-0312">Gluconeogenesis</keyword>
    <keyword evidence="4 7 8" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="5 7 8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton donor" evidence="7">
        <location>
            <position position="356"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="387"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="515"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC94193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="550" mass="60580" checksum="EBB2D5356DA843FD" modified="2018-07-18" version="1">MSFTPLSDTPAYKQLQLHQQQMHQQGLEISHLFDQQSDRFTQFSLSAAGVFLDYSKNRITETTKELLCDFARQQQVELQRDAMFSGEKINFTEQRAVLHTALRAPSNTPQRIDGIDINAEVHMVLAQMQAFVEKVHSGVWRGASGLVITDVVNIGIGGSDLGPKMVCQALRSFAHQGIQSHFVSNLDGHALDAVLSQVNPASTLFIISSKTFTTADTMLNAHSARAWFLQHFSAADLSRHFVAVSSNQPAVQAFGIAPENRFGFWDWVGGRYSLWSAIGLPIALSLGFAHFRALLDGAHAMDVHFQQAPIEQNMPILLAMLGIWNRDLLGCGSLSIAAYHHDLRAFPNYLQQLDMESNGKRINHHGQTVDVATGPIIWGDVGTNGQHAYFQHLHQSSDITPVDFIAALRPQHHLAEHQLMLLANCFAQSQALMRGKTAQQVTTEMQTQGMSDEQISLLLPHRIFAGNRPSNTILLDELSPMRLGALIALYEHKVAVQGFFWGINSFDQWGVELGKVLAKAIEGDLHSGTTATSHDSSTAGLIAKVRAAGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2M9</accession>
    <name>A0A2S9H2M9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0866</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94245">
        <property type="protein sequence ID" value="PRC94245"/>
        <property type="gene ID" value="S2091_0866"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015580103" evidence="2">
        <location>
            <begin position="26"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="164"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="201" mass="21339" checksum="8D6434134BB8D3F4" modified="2018-07-18" version="1">MTKVFFPVILLLTVASCATDSPQVAGPVSTQDRLGKAFVSPLNDLNIVQTTIPPVITEALKNPYQIPANISCKTIAEQVRLLDIALGADLDAIVVTESTTQLEQGGAFAQDEAVGSIERTIQGVIPFRSWIRKFSGAEKRSKELTAAIAAGVVRRAFLKGMGQERRCEPPAAPLKRPAVVPASATTTPATPPVKPPTLTVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2R7</accession>
    <name>A0A2S9H2R7_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 8">DNA-directed RNA polymerase subunit beta</fullName>
            <shortName evidence="6">RNAP subunit beta</shortName>
            <ecNumber evidence="6 8">2.7.7.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">RNA polymerase subunit beta</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Transcriptase subunit beta</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rpoB</name>
        <name evidence="15" type="ORF">S2091_1329</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 8">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 6 8">
            <text>a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="6 8">The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6 7">Belongs to the RNA polymerase beta chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="6 8"/>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94156">
        <property type="protein sequence ID" value="PRC94156"/>
        <property type="gene ID" value="S2091_1329"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed 5'-3' RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032549">
        <property type="term" value="F:ribonucleoside binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00653">
        <property type="entry name" value="RNA_pol_B_RPB2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.270.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01321">
        <property type="entry name" value="RNApol_bact_RpoB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042107">
        <property type="entry name" value="DNA-dir_RNA_pol_bsu_ext_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019462">
        <property type="entry name" value="DNA-dir_RNA_pol_bsu_external_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015712">
        <property type="entry name" value="DNA-dir_RNA_pol_su2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007120">
        <property type="entry name" value="DNA-dir_RNAP_su2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037033">
        <property type="entry name" value="DNA-dir_RNAP_su2_hyb_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010243">
        <property type="entry name" value="RNA_pol_bsu_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007121">
        <property type="entry name" value="RNA_pol_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007644">
        <property type="entry name" value="RNA_pol_bsu_protrusion"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007642">
        <property type="entry name" value="RNA_pol_Rpb2_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037034">
        <property type="entry name" value="RNA_pol_Rpb2_2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007645">
        <property type="entry name" value="RNA_pol_Rpb2_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007641">
        <property type="entry name" value="RNA_pol_Rpb2_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014724">
        <property type="entry name" value="RNA_pol_RPB2_OB-fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20856">
        <property type="entry name" value="PTHR20856"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04563">
        <property type="entry name" value="RNA_pol_Rpb2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04561">
        <property type="entry name" value="RNA_pol_Rpb2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04565">
        <property type="entry name" value="RNA_pol_Rpb2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10385">
        <property type="entry name" value="RNA_pol_Rpb2_45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00562">
        <property type="entry name" value="RNA_pol_Rpb2_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04560">
        <property type="entry name" value="RNA_pol_Rpb2_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02013">
        <property type="entry name" value="rpoB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01166">
        <property type="entry name" value="RNA_POL_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6 8" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="3 6 8" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6 8" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 6 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RNA_pol_Rpb2_1" evidence="12">
        <location>
            <begin position="27"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="domain" description="RNA_pol_Rpb2_2" evidence="11">
        <location>
            <begin position="156"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="domain" description="RNA_pol_Rpb2_2" evidence="11">
        <location>
            <begin position="355"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="domain" description="RNA_pol_Rpb2_3" evidence="13">
        <location>
            <begin position="519"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="domain" description="RNA_pol_Rpb2_45" evidence="14">
        <location>
            <begin position="597"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="domain" description="RNA_pol_Rpb2_6" evidence="9">
        <location>
            <begin position="725"/>
            <end position="1290"/>
        </location>
    </feature>
    <feature type="domain" description="RNA_pol_Rpb2_7" evidence="10">
        <location>
            <begin position="1292"/>
            <end position="1366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00024550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF04560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF04561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF04563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF04565"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF10385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="PRC94156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="1368" mass="152181" checksum="67A988EB80E3208C" modified="2018-07-18" version="1">MHYSFTEKKRIRKSFAKRANVHNVPFLLATQLESYLGFLQADNVPSQRKNEGLQSAFTSIFPIVSHNGFARLEFLSYVLGDPAFDVKECQQRGLTYASPLRAKVRLVILDKESPTKPVVKEMKEQEVYMGELPLMTTTGSFVINGTERVIVSQLHRSPGVFFEHDRGKTHSSGKLLFSARIIPYRGSWLDFEFDPKDILFFRVDRRRKMPVTILLKAIGMSNEQILANFFVFDNFILHREGAEMEFVAEHLRGEVARFDIADKSGTVIVAKDKRINSRHVRDIEAAKIKNISVPEDYLYGRVLAKNVIDAETGEIIANANDELTEELLASLRTANVSNVQTLYINDLDQGGYISNTLRSDDTADQMSAKVAIYRMMRPGEPPTEDSVEALFNGLFYNADRYDLSAVGRMKFNRRIGREELTGSMTLSNEDVLAVIKILVELRNGRGEVDDIDHLGNRRVRCVGELAENQFRAGLVRVERAVKERLGQAEADNLMPHDLINSKPISAAIREFFGSSQLSQFMDQTNPLSEITHKRRISALGPGGLTRERAGFEVRDVHPTHYGRVCPIETPEGPNIGLINSLALYARLNEYGFLETPYRKVVDSKITTQIDYLSAIEEGRYIIAQANATIDANGKLSDELVSSREAGETILVTPERVQYMDVATGQVVSVAASLIPFLEHDDANRALMGANMQRQAVPCLRPEKALVGTGIERTVAVDSGTTVQALRGGKVDYIDAGRIVIRVNDAEATAGDVGVDIYNLIKYTRSNQNTNINQRPIVKVGDVVARGDVLADGASTDLGELALGQNMLVAFMPWNGYNFEDSILISEKVVADDRYTSIHIEELSVVARDTKLGAEEITRDISNLAENQLARLDEAGIVYIGAEVTAGDTLVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDTSLRVPSGMVGTVIDVQVFTREGIARDKRAQQIIDDELKRYRLDLNDQMRIVEGDAFERLERMLIGKVANGGPQKLAKGTVIDKEYLVAVDRHHWFDIRPADDDAAAALEAIKDSIAEKRHQFDLAFEEKRTKLTQGDELPPGVQKMVKVYLAVKRRLQPGDKMAGRHGNKGVVSRIVPIEDMPYMADGTPADVVLNPLGVPSRMNVGQVLEVHLGWAAKGLGLRIGEMLKAHTAMQELRKFLASIYNESGKKEDLDSFSDDEILELANNLKHGVPFATPVFDGAHEGEIRRMLDLAYPDHIAKQLGMTPSKNQVTLYDGRTGESFERNVTVGYMHVLKLHHLVDDKMHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYVLQEMLTVKSDDVNGRTKVYENLVKGDHVIDAGMPESFNVLVKEIRSLGIDIDLERK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2R9</accession>
    <name>A0A2S9H2R9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major Facilitator Superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_0900</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94279">
        <property type="protein sequence ID" value="PRC94279"/>
        <property type="gene ID" value="S2091_0900"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="50"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="76"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="100"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="136"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="167"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="218"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="248"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="275"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="302"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="341"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="367"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="8"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC94279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="397" mass="42690" checksum="12486A7C2CA720E8" modified="2018-07-18" version="1">MKDTTGLSRYQHWLFCLATGFSVAAVVYHQAMTQMIAASFQVPTTSLWDLSVATQFGYGIGLILGLPLGDMVMPRKLIPTVVTSLGLVLLLVGVSSNLAAMTALCFLAGVLSIGGQLLIAYSAKTAAATTAGRPKIVDNLLSALFAGLLLARVLGGWGAEKIGWRQVYLLAGGVTVLLGLSLFYSVRRQTQIDPNLRYGQMLRRQAQLWQSLPELRRLALVAACFFAALNGIWANLASLTHSSLNWSASQTGLLAFTAVVALWAPALVRRLQQRLHWSGVIVLLGLCMGAVSLAGYWFGSSVFMIIIFLIVSDVSVRSVHVISQGKVLSIDPAAASRLNSLFMTVFFIGAALGSWLGGIAVRHFSWAGMYLFPLVCALLGVLLLRIRDGQLSFSRAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2V0</accession>
    <name>A0A2S9H2V0_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Aldehyde dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_0884</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3 7">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94263">
        <property type="protein sequence ID" value="PRC94263"/>
        <property type="gene ID" value="S2091_0884"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016620">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006081">
        <property type="term" value="P:cellular aldehyde metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012394">
        <property type="entry name" value="Aldehyde_DH_NAD(P)"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43570">
        <property type="entry name" value="PTHR43570"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036492">
        <property type="entry name" value="ALDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
        <property type="entry name" value="ALDEHYDE_DEHYDR_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldedh" evidence="8">
        <location>
            <begin position="28"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="active site" evidence="4 5">
        <location>
            <position position="215"/>
        </location>
    </feature>
    <feature type="active site" evidence="4 6">
        <location>
            <position position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR036492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR036492-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC94263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="490" mass="54059" checksum="F61ADE84C5525D68" modified="2018-07-18" version="1">MNDTIHKLTTIFALQKDACLATPYPQEAQRKNNLKALRIALLRYQDQLTTAMSEDFGRRSEFECKMVDVLAPALQVDHALTNLRRWMKPQRRKTDWLFITNSAKVVYQPKGVVGVIAAWNFPVIEAVGPLITALAAGNRVMIKMSEFSPRCTEVLRHMLAEIFHEDQVAVFGGGVEIGQAFSNLALDHIVFTGSPAIGKEIMRAAANNLTPVTLELGGKSPAVVADSASITAAAQSIAHGKAFNSGQACVAPDYALVPRGQIDEFVSAVVTAFKHMYPDPVTDLQYTSMASERHADRVRELLDDAVAKGATVIPCGVGNGGRIVPLQVVTGVTDDMRIMQEELFNPILPVIAYDLMEEAIHYVTSRPRPLALYYYGRDRVEATRWTRDVHSGGMTINDWAWHVFQCDLPFGGSGNSGIGSWRGPEGFRALSHAKAVFTEQRWFPASFFRPPYGNLIQQMSLKIFLGDADSSLAEHNPDIMDQTTYATKTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H323</accession>
    <name>A0A2S9H323_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Pentapeptide repeats (9 copies)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1003</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94382">
        <property type="protein sequence ID" value="PRC94382"/>
        <property type="gene ID" value="S2091_1003"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001646">
        <property type="entry name" value="5peptide_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13599">
        <property type="entry name" value="Pentapeptide_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="103" mass="11337" checksum="BE1934F4FEC136CB" modified="2018-07-18" version="1">MSAIVLKRCHYQLEVQDANLANSSFEDVGFVGSSFNLVSMEKAEFTKVSMADANFKGIRFDNARFENANFVNTDIRASNYEGLRIEGILVTDMLAAYGARAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H391</accession>
    <name>A0A2S9H391_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1070</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AB hydrolase superfamily. Lipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94449">
        <property type="protein sequence ID" value="PRC94449"/>
        <property type="gene ID" value="S2091_1070"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004806">
        <property type="term" value="F:triglyceride lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005152">
        <property type="entry name" value="Lipase_secreted"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029171">
        <property type="entry name" value="Esterase_LipA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="428" mass="47519" checksum="97576BDF1679A144" modified="2018-07-18" version="1">MVFPIITLIALGVLLWQLNLLHFRRLPITLYATGIFLFATSAATQGQENEIRVPSGVTYQLIATYSVDRLNQILTSELKEFSDFPMSYPPARYPVKLYRITYPSVIPEHNSRPTSASGLLAVPESGADTMPVVSYQHGTVFSKTEVPSHPDNSMETRLMIAQFAGQGYMVIGADYFGKGISPETDSFLVKASTQQACLDMMLAAQAVSVNLKLHWGPLFLSGWSQGGWSTMVFLNKLESLGIPVKAAAVASAPNDMFAIMNRWLHAPENHDAVYLPGLAILQINAYEEYYGLPNLTLSAFKPQYQSIARDLYLNKITYAEAGPKLPKRMNDLLQDDFIAGSSLGSSRYWALLQDSQAFRWRSITPLHTYYGDEDEVVPAYIATLPVSYQKFVGGASAVGIEVKKANHRGTFVYAVANQKKWFDQLLTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3A9</accession>
    <name>A0A2S9H3A9_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Pyridoxal phosphate homeostasis protein</fullName>
            <shortName evidence="1">PLP homeostasis protein</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_1044</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94423">
        <property type="protein sequence ID" value="PRC94423"/>
        <property type="gene ID" value="S2091_1044"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02087">
        <property type="entry name" value="PLP_homeostasis"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001608">
        <property type="entry name" value="Ala_racemase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029066">
        <property type="entry name" value="PLP-binding_barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011078">
        <property type="entry name" value="PyrdxlP_homeostasis"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10146">
        <property type="entry name" value="PTHR10146"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01168">
        <property type="entry name" value="Ala_racemase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004848">
        <property type="entry name" value="YBL036c_PLPDEIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51419">
        <property type="entry name" value="SSF51419"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00044">
        <property type="entry name" value="TIGR00044"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01211">
        <property type="entry name" value="UPF0001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ala_racemase_N" evidence="4">
        <location>
            <begin position="6"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="1 2">
        <location>
            <position position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR004848-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC94423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="233" mass="25678" checksum="1937D3B4F00E23D1" modified="2018-07-18" version="1">MSTILINLQAVQQQIIHAAQIAGRSPHEIQLLAVSKTFNAEAVLEAGKAGQTAFGENYLQEALDKMAEVRRLSPELALEWHFIGPIQSNKTRLIAQNFSWAHAVDRLKIAERLSEQRPDNLPPLNICLQINISEQETKSGVPINQAAQLAQQIAALPNVRLRGLMAIPEPAQTLEQQRTPYQQIKTLQEQLNQQGLALDTLSMGMSADLEAAILEGSTMVRIGSAIFGKRNYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3J7</accession>
    <name>A0A2S9H3J7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">VanZ like family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0558</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94555">
        <property type="protein sequence ID" value="PRC94555"/>
        <property type="gene ID" value="S2091_0558"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006976">
        <property type="entry name" value="VanZ-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04892">
        <property type="entry name" value="VanZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="119"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="153"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="218"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="250"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="276"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="307"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="344"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="domain" description="VanZ" evidence="2">
        <location>
            <begin position="20"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="375" mass="41992" checksum="433DB82E4C1AECA5" modified="2018-07-18" version="1">MQATPVNPHSSPLVRVALLAYTFLIVYASWYPFSDWHTIGLSPLAYFSEALPRYWTFFDVSINVLGYIPFGILLMLACYPWLPRRWAALLCMLAGSLVSGTMEAVQTYLPSRVPSILDFITNCSGLFIGILMGCVLTPWLLQKDLLRQIRVRWFVPSMSNGLIIVALWPLAQIYPQGYMFGLGQLVPVLSNWLNIYLGIPIDLGSFIRQGAQLSIEQYWLSETIITCCGLIGAVLLFLCLLQPKAPKARLVTLLIFICLGVKSLALALLFKPEHAYSWFSPGAQAGLLVGCLMLYGLAFTPARVQRHLAIFMLTISLLVINFVPGNPYFTDTLSTWVQGKFLNFNGAAQFLAILWPWLAIWFLLHYQPAKSTNPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3P0</accession>
    <name>A0A2S9H3P0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0605</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94602">
        <property type="protein sequence ID" value="PRC94602"/>
        <property type="gene ID" value="S2091_0605"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015708634" evidence="1">
        <location>
            <begin position="23"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="189" mass="21371" checksum="33D081DF53021401" modified="2018-07-18" version="1">MKKFAFTFLFVFASNFSAIAIAAEPIIDNERVTVWDTTMPLPPAQHDFISVPLSHKGTAVFGHRGDISGEADARTIVIELKEHAVPPLANTSGYLDAYDRPHIVKLLENDKVIVWSYRWNLGEPTPMHFHSKDVVIVYEEDTALKSTMPDGNNVLNEYKFADTRFNRRNRTHAELLVRDTGSAMITELK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H464</accession>
    <name>A0A2S9H464_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Malonate transporter, MadL subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0726</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94723">
        <property type="protein sequence ID" value="PRC94723"/>
        <property type="gene ID" value="S2091_0726"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004690">
        <property type="entry name" value="Maln_transptMadL"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03817">
        <property type="entry name" value="MadL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00807">
        <property type="entry name" value="malonate_madL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="62"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="92"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="142" mass="14855" checksum="C56746EE01BD93BA" modified="2018-07-18" version="1">MIIYGTALLAVCHLLGIFIGDLLGKIIGVQTNVGGVGIAMMLLIFARMFMEPRGLMPKPTEAGVTFWAALYIPVVVAMAAQQNVVAALRGGHVAILAAFGAVVSCACIIALINRMEPKSDVDPFADDTEMPEAAAVDIKPTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H494</accession>
    <name>A0A2S9H494_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Polyamine aminopropyltransferase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Putrescine aminopropyltransferase</fullName>
            <shortName evidence="4">PAPT</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Spermidine synthase</fullName>
            <shortName evidence="4">SPDS</shortName>
            <shortName evidence="4">SPDSY</shortName>
            <ecNumber evidence="4">2.5.1.16</ecNumber>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">speE</name>
        <name evidence="7" type="ORF">S2091_0699</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>putrescine + S-adenosyl 3-(methylsulfanyl)propylamine = H(+) + S-methyl-5'-thioadenosine + spermidine</text>
            <dbReference type="Rhea" id="RHEA:12721"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17509"/>
            <dbReference type="ChEBI" id="CHEBI:57443"/>
            <dbReference type="ChEBI" id="CHEBI:57834"/>
            <dbReference type="ChEBI" id="CHEBI:326268"/>
            <dbReference type="EC" id="2.5.1.16"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Amine and polyamine biosynthesis; spermidine biosynthesis; spermidine from putrescine: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer or homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the spermidine/spermine synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.16" evidence="4"/>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94696">
        <property type="protein sequence ID" value="PRC94696"/>
        <property type="gene ID" value="S2091_0699"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00248">
        <property type="reaction ID" value="UER00314"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004766">
        <property type="term" value="F:spermidine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008295">
        <property type="term" value="P:spermidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00198">
        <property type="entry name" value="Spermidine_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030374">
        <property type="entry name" value="PABS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030373">
        <property type="entry name" value="PABS_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001045">
        <property type="entry name" value="Spermi_synthase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01330">
        <property type="entry name" value="PABS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51006">
        <property type="entry name" value="PABS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 4 5" id="KW-0620">Polyamine biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0745">Spermidine biosynthesis</keyword>
    <keyword evidence="1 4 5" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="35"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="69"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="100"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="141"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="167"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="192"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="domain" description="PABS" evidence="6">
        <location>
            <begin position="214"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-methyl-5'-thioadenosine binding" evidence="4">
        <location>
            <begin position="346"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4 5">
        <location>
            <position position="364"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="238"/>
        </location>
        <ligand>
            <name>S-methyl-5'-thioadenosine</name>
            <dbReference type="ChEBI" id="CHEBI:17509"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="268"/>
        </location>
        <ligand>
            <name>spermidine</name>
            <dbReference type="ChEBI" id="CHEBI:57834"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="292"/>
        </location>
        <ligand>
            <name>spermidine</name>
            <dbReference type="ChEBI" id="CHEBI:57834"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="312"/>
        </location>
        <ligand>
            <name>S-methyl-5'-thioadenosine</name>
            <dbReference type="ChEBI" id="CHEBI:17509"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC94696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="503" mass="56753" checksum="706A927B519BA098" modified="2018-07-18" version="1">MPKKILILSVFVVASCGLAYELIAGALSSYLLGDSILQFSTIIGCYLFAMGVGAHFSKYIHDDDLLARFVDIELAVGLIGGISAALLFLTFSWMSAPFRTLLYVLVFMIGALVGMEVPLVMRVLNSRQTEFNELVSRVLTFDYLGALAVSLLFPLVLAPYLGLVRTGFLFGMLNIGVALWTIHTFRHELKNVGARLLRAATILCLLMAGFSLSDRMVYWGEHGLYGDEIVFSTTTPYQRLVITRWKDDLRLYINGNLQFSSRDEYRYHEALVHPAMQALPWARSVLVLGGGDGLALREILRYSNIQHVTLVDLDPAMTNAFTHRSELTQLNHSSFSDPRVHVVNADAAIWLQNNQDMFDAVIVDFPDPSSFALGKLYSVPFYGIVKKHVAANGLIVVQSTSPFFAPHAFWTVEATLKEVGLLTYPYHLYVPSFGEWGFILASPQQHFEPPTQYSLPMRYLSKETTHEMFTFPPDMQRIQMEPNHLDTQSLVREFEQDWRQVIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4B2</accession>
    <name>A0A2S9H4B2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Amidases related to nicotinamidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0017</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94822">
        <property type="protein sequence ID" value="PRC94822"/>
        <property type="gene ID" value="S2091_0017"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.850">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000868">
        <property type="entry name" value="Isochorismatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036380">
        <property type="entry name" value="Isochorismatase-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00857">
        <property type="entry name" value="Isochorismatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52499">
        <property type="entry name" value="SSF52499"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Isochorismatase" evidence="1">
        <location>
            <begin position="7"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="184" mass="20323" checksum="4EE398F6E9AD19EC" modified="2018-07-18" version="1">MKNFEPVLIIVDMQKGMQSYKPDHRNNPQAESNIAKLLAAWRQTGGLVIHVRHMSRTVGSVFWPGQIGAEFQDELQPLNGEHVVEKNVPDAFINSGLERWLRVRNINDVVIVGVSTNNSVEATARSAGNLGFKAIVVADGTYAYDQVDYAGTLRDADVVHAMALSNLDGEYAMIMTTNELLKAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4E3</accession>
    <name>A0A2S9H4E3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0047</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94852">
        <property type="protein sequence ID" value="PRC94852"/>
        <property type="gene ID" value="S2091_0047"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015485081" evidence="1">
        <location>
            <begin position="20"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="141" mass="15734" checksum="4BF9829ADA0DC9A0" modified="2018-07-18" version="1">MNKLFVFSFLSALSLSSLAQTSNVETITMTADKEGMLRAQKYTMLPDEFYNFVGTYELSNGMTLSLYSRSSEMFAQLNNQARLRIIATASNSFISLDRQLKMRIDLDQNGEASGEVYIPVPSPVIASSDNGNQQFKVLTLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4F6</accession>
    <name>A0A2S9H4F6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_0043</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DoxX family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94848">
        <property type="protein sequence ID" value="PRC94848"/>
        <property type="gene ID" value="S2091_0043"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032808">
        <property type="entry name" value="DoxX"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07681">
        <property type="entry name" value="DoxX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="50"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="75"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="106"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC94848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="131" mass="14030" checksum="415798861D0C1264" modified="2018-07-18" version="1">MNTLFHKLNPYFNLAARILMSLIFVVSGFGKINEYAGTQGFMQSLGIPGALLPLVIVVEFGGGLALLLGLQTRLAAFLLAGFALLAGSIVHFHPNDQESMIVFMDNLAIIGGLLLFAQYGGGAFSLDKLRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4H0</accession>
    <name>A0A2S9H4H0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0074</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94879">
        <property type="protein sequence ID" value="PRC94879"/>
        <property type="gene ID" value="S2091_0074"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="37" mass="4326" checksum="40B272E92613B910" modified="2018-07-18" version="1">MYYGPHVRYLFHPDWGGTTVGILFAAIIALAIRYKWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4K2</accession>
    <name>A0A2S9H4K2_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 6">Superoxide dismutase</fullName>
            <ecNumber evidence="2 6">1.15.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_0107</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Destroys radicals which are normally produced within the cells and which are toxic to biological systems.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>2 H(+) + 2 superoxide = H2O2 + O2</text>
            <dbReference type="Rhea" id="RHEA:20696"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:18421"/>
            <dbReference type="EC" id="1.15.1.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the iron/manganese superoxide dismutase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.15.1.1" evidence="2 6"/>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94912">
        <property type="protein sequence ID" value="PRC94912"/>
        <property type="gene ID" value="S2091_0107"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004784">
        <property type="term" value="F:superoxide dismutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.990">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.55.40.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001189">
        <property type="entry name" value="Mn/Fe_SOD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019833">
        <property type="entry name" value="Mn/Fe_SOD_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019832">
        <property type="entry name" value="Mn/Fe_SOD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019831">
        <property type="entry name" value="Mn/Fe_SOD_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036324">
        <property type="entry name" value="Mn/Fe_SOD_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036314">
        <property type="entry name" value="SOD_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02777">
        <property type="entry name" value="Sod_Fe_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00081">
        <property type="entry name" value="Sod_Fe_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000349">
        <property type="entry name" value="SODismutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01703">
        <property type="entry name" value="MNSODISMTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46609">
        <property type="entry name" value="SSF46609"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54719">
        <property type="entry name" value="SSF54719"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00088">
        <property type="entry name" value="SOD_MN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sod_Fe_N" evidence="7">
        <location>
            <begin position="2"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="Sod_Fe_C" evidence="8">
        <location>
            <begin position="89"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="27"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="74"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="157"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="161"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000349-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000414"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC94912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="192" mass="21384" checksum="E80459C5FDD548FF" modified="2018-07-18" version="1">MEHTLPALPYAMDALAPHISKETLEYHYGKHHQTYVTNLNNLIKGTEFENSTLEEIVKKSSAGIFNNSAQIWNHTFYWNGLKPNGGGVPTGALAAAIDAKWGSFDAFKDAFTKSCIGNFGSSWTWLVKKADGTLDIVNTSNAATPLTTTDKPLVTCDLWEHAYYIDYRNARPKYLEAFWSLVNWDFAAANLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4L2</accession>
    <name>A0A2S9H4L2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Phosphomannomutase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">S2091_0117</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the phosphohexose mutase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94922">
        <property type="protein sequence ID" value="PRC94922"/>
        <property type="gene ID" value="S2091_0117"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016868">
        <property type="term" value="F:intramolecular transferase activity, phosphotransferases"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005844">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016055">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I/II/III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005845">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005846">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005843">
        <property type="entry name" value="A-D-PHexomutase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036900">
        <property type="entry name" value="A-D-PHexomutase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016066">
        <property type="entry name" value="A-D-PHexomutase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005841">
        <property type="entry name" value="Alpha-D-phosphohexomutase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02878">
        <property type="entry name" value="PGM_PMM_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02879">
        <property type="entry name" value="PGM_PMM_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02880">
        <property type="entry name" value="PGM_PMM_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00408">
        <property type="entry name" value="PGM_PMM_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00509">
        <property type="entry name" value="PGMPMM"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53738">
        <property type="entry name" value="SSF53738"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55957">
        <property type="entry name" value="SSF55957"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00710">
        <property type="entry name" value="PGM_PMM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5 7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PGM_PMM_I" evidence="9">
        <location>
            <begin position="10"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_II" evidence="10">
        <location>
            <begin position="156"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_III" evidence="11">
        <location>
            <begin position="258"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_IV" evidence="8">
        <location>
            <begin position="386"/>
            <end position="453"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PRC94922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="465" mass="50091" checksum="3416E1BF0D2C31DB" modified="2018-07-18" version="1">MTTSTPISKSIFKAYDIRGIVGKTLDTNVAYQLGQAFGSAVLAKNERTVVIGRDGRLSGPELSAALAQGLQAAGVDVIDLGVVATPMVYFGTHILDAQSGIMVTGSHNPPDYNGFKMVLAGEAIYGDTIQALYHTIVAQDFANGAGQYQQHNIRAAYLERIISDIKLARPMKIAVDCGNGVAGAFAGDLYRGLNCQVDELFCEVDGNFPNHHPDPAHPENLQDLIAHVKNSDAELGLAFDGDGDRLGVVTKDGSIIYPDRQLMLFAEDVLTRNPGAQILYDVKCTRHIAAWLKARGGSPLMWKTGHSLVKAKMRETGAPLGGEMSGHIFFKDRWYGFDDGLYAGARLLELLSRVEDPSAVLNSLPQSSSTPELQLTLNEGENFTLIAQMQAAEQVQAHFADAEQIISIDGLRVEYADGFGLARSSNTTPVIVMRFEAETAAALALIQAAFKRAILAVKPDAKLPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4P7</accession>
    <name>A0A2S9H4P7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0041</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94846">
        <property type="protein sequence ID" value="PRC94846"/>
        <property type="gene ID" value="S2091_0041"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="79"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="105"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="141"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="163"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="191"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="226" mass="25237" checksum="1CDCC1D6B3A35593" modified="2018-07-18" version="1">MMITRRVFDQFFYFRMALLLAAIVIYGFSHTVDGSLIHPINPPPAIFYVHASVFASWVVLLIVQTGLARSNNVALHRRLGWFGIFLGGVIPVLGVSTAITSQQEATSHLFFAISLNDMILFTIAFWLAIYWRKKPEYHKRLMLIATCCLMGAAIARFPEVPGIPWAYGGVDLLILLGALRDVVVSRKVHVVFRYALPCVIAGQVFALYLATDPSPVWAALLQIVFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4Q3</accession>
    <name>A0A2S9H4Q3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Imidazolonepropionase and related amidohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0116</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94921">
        <property type="protein sequence ID" value="PRC94921"/>
        <property type="gene ID" value="S2091_0116"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="SSF51338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015400135" evidence="1">
        <location>
            <begin position="24"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="domain" description="Amidohydro-rel" evidence="2">
        <location>
            <begin position="84"/>
            <end position="431"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="438" mass="46008" checksum="7B87DA048770FF6A" modified="2018-07-18" version="1">MKLSISYLLTGAMSIVLSHTTLAAEQAPAPHIIVLKAAHLFDSVSGKLVDNGVIVISGNKIQTVGTSSTKLPDGAQVIDLGDATLLPGFIDAHVHFSGEMSDNWYGDWFNGMMRFPAEQALYGAHYAKITLEAGVTTVRDVGSTDYISLGLRNAIKAGIIPGPRMLVANYAIGSTGGHADQDPVPTQRIAAAGPIQGVCNGADECRAAVRYQIKFGADVIKFMPSGGVLSLSDPVDIPELTQEEMNAIVSEAHAWKRKVAAHCHGDKAAKMAIAAGVDSIEHGTFLEDDTLLEMKKKHVYLVPTLSAGNSIGNKLDKFPPAIAEKARVASAQMQTMFQHAVKLGVPIAMGTDAAVGPHGQNALEFVLMTKNSFTPAQSLMAGTANGADLLGIADQTGTLQAGKYADIVAVAGNPLSDISTTQHPLFVMKEGVIYLGGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H559</accession>
    <name>A0A2S9H559_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Beta_helix domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_0320</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95125">
        <property type="protein sequence ID" value="PRC95125"/>
        <property type="gene ID" value="S2091_0320"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039448">
        <property type="entry name" value="Beta_helix"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006626">
        <property type="entry name" value="PbH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13229">
        <property type="entry name" value="Beta_helix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00710">
        <property type="entry name" value="PbH1"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="SSF51126"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015692827" description="Beta_helix domain-containing protein" evidence="2">
        <location>
            <begin position="17"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="domain" description="Beta_helix" evidence="3">
        <location>
            <begin position="184"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC95125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="540" mass="54933" checksum="0F1E806E16725AB0" modified="2018-07-18" version="1">MKNGIFAICLLTLALAGCGGGGSSSSGGSTTPTSPITPPIVPPVTPPITPPTIPPITPPVTPVGTPYYVAPTGSDSNPGTLALPWKTLQKAVSTVGPGSVINARAGTYTEQVIFTTANSGSASGGYITLQNYPGEKAIIDGTSIVLSANSANMALVNLTDVSYVRVIGFEICNLTTNSAAIVPAGIFVSGSGSNIELRNNYVHNIVTTVNSASGNAFGIGIYGTEAPASINGLILDGNEVAFLKTGSSESVSVNGNVENFQVTNNVVHDNDNIGIDFIGFEGTSPNPAYDQARNGEVSGNVVYNISSYVNSAYPSGSYGADGLYVDGGTNIVMERNIVYQTDIGIEVASEHAGHLGSFVTLRSNLIYKNNLTGISLGGTSATANGGTDSCGIFNNTLYQNDTTGSGTGEIALQNHLTNIQFANNVVISSTQGIFISGVSSALPAMNGDLYFSGGATGTWQWKGATYNSLAAFTTASGNEKNGLAADPVLISPTAGNFKLGAGSPAINAGIALTATQVGSLDLAGNPRVQSTGIDIGAYEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5C1</accession>
    <name>A0A2S9H5C1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phasin: phasin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0261</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95066">
        <property type="protein sequence ID" value="PRC95066"/>
        <property type="gene ID" value="S2091_0261"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018968">
        <property type="entry name" value="Phasin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010127">
        <property type="entry name" value="Phasin_subfam-1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09361">
        <property type="entry name" value="Phasin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01841">
        <property type="entry name" value="phasin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phasin_2" evidence="2">
        <location>
            <begin position="6"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="153"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC95066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="189" mass="19923" checksum="EDAC16B05EE25522" modified="2018-07-18" version="1">MFTLPEQFSAATKANFDAQLAMLSAFTSKAIESVEKVVELNMTVAKTSFEESNIAAKQLISAKDAQEFFSLTAAHAQPNADKAVAYARHLASITSGAQAEFTKAAEAHVAETNRKVVAFVEEVSKNAPAGSENAIALLKSAIGNANASYDQFNKSTKQAVETLEANLNTAVNQISQATAKAAPRAAKKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5D9</accession>
    <name>A0A2S9H5D9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Chemotaxis signal transduction protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0373</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95178">
        <property type="protein sequence ID" value="PRC95178"/>
        <property type="gene ID" value="S2091_0373"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036061">
        <property type="entry name" value="CheW-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002545">
        <property type="entry name" value="CheW-lke_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01584">
        <property type="entry name" value="CheW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00260">
        <property type="entry name" value="CheW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50341">
        <property type="entry name" value="SSF50341"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50851">
        <property type="entry name" value="CHEW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CheW-like" evidence="1">
        <location>
            <begin position="8"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC95178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="156" mass="16329" checksum="291A9B6BF2F8CD78" modified="2018-07-18" version="1">MTSSIALFSPFLICRSGVQSCGFPLEHVAETMRALPVEVFPDMLPFMFGVSIIRGVAVPVVNLAGLLGGATDTGVTRYVTVRLGNRLVAFAVGSVVGVSQLAADVIDGLPPLLGEADRSIVAAIGTLDSNLFLVLEASRVIPESVWQVLDARGMST</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5R3</accession>
    <name>A0A2S9H5R3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0476</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95281">
        <property type="protein sequence ID" value="PRC95281"/>
        <property type="gene ID" value="S2091_0476"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC95281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="34" mass="3885" checksum="2342564E80548382" modified="2018-07-18" version="1">MAGYKLLNENGNHYDLNGTNKFQLNVQLMRAVMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GS91</accession>
    <name>A0A2S9GS91_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4710</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000049">
        <property type="protein sequence ID" value="PRC90583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90583">
        <property type="protein sequence ID" value="PRC90583"/>
        <property type="gene ID" value="S2091_4710"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC90583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="105" mass="11221" checksum="3838F46BA41D3D86" modified="2018-07-18" version="1">MTRAILKVIAAGEHARIVCDKLPGSKIENGTVIMSSALGSDESLNAHLVWLWGMVKNERRVLKSAVEAGARIVCECSASKGEIRLLPNGAEMLHLLGAELVISSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSD2</accession>
    <name>A0A2S9GSD2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Filamentous hemagglutinin family N-terminal domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_4672</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000043">
        <property type="protein sequence ID" value="PRC90621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90621">
        <property type="protein sequence ID" value="PRC90621"/>
        <property type="gene ID" value="S2091_4672"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043170">
        <property type="term" value="P:macromolecule metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006807">
        <property type="term" value="P:nitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044238">
        <property type="term" value="P:primary metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010069">
        <property type="entry name" value="CdiA_FHA1_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024973">
        <property type="entry name" value="ESPR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008638">
        <property type="entry name" value="Filamn_hemagglutn_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025157">
        <property type="entry name" value="Hemagglutinin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13018">
        <property type="entry name" value="ESPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13332">
        <property type="entry name" value="Fil_haemagg_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00912">
        <property type="entry name" value="Haemagg_act"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="SSF51126"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01901">
        <property type="entry name" value="adhes_NPXG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01731">
        <property type="entry name" value="fil_hemag_20aa"/>
        <property type="match status" value="27"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="50"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="domain" description="Haemagg_act" evidence="4">
        <location>
            <begin position="88"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1812"/>
            <end position="1893"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2285"/>
            <end position="2311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2378"/>
            <end position="2399"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2605"/>
            <end position="2652"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2716"/>
            <end position="2739"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1816"/>
            <end position="1893"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="2627"/>
            <end position="2652"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC90621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="3413" mass="348335" checksum="356A82AAC0921295" modified="2018-07-18" version="1">MNKQAYRVIFSKVSSTYIAVAEITSSQGKSKGTSVSNSTSTSFNSRCMRFATLSVVVAALFGPVIMAHAQMVAYKNGAGPRPTIDQTANGRPLVQIVTPNSSGLSHNKYEQFNVNSNGAILNNSATITQTQLGGYVEGNPHILPGNSAKIILNEVMSTNRSQLNGYIEVAGQRAEVIIANPNGISVGGGAGFINASRGVLTTGMPTFGGDGSLAAFRVSKGDIQINAGGLNATGVEQLDLIARSVQVNDNLWANQLNVITGSNQVNYNNLGVQVIAGADGKPTIGLDSSALGGMYAQKIMLVGTEAGVGVKALGNIAASAGDLTVDSHGKVLLTGKTNAAGQIHLSSNDDISNTGRLYGQQTVVINSAGQVNNTGTLAAFNDLAIQSATLNSSGIVAAGINDAGQASQPGNLTLSTTDLITATGQNTAGGQLAITGSAINLANAATSANGATTLLATAGDINHTGATLHSTGRVTATASGAVVNDAGVIQAAQITTNSAALSNVAGTLIQSGADNTSLQTSGNFNNTGGTLVSNAQHLQLQTGSLTNNDGNLSHAGNGTLTITTGALENVAGKMVSNGRVMVTATTLNNHRGQVVANRAAALSLNGDLMNSQGNIQSAEALALHANNIDNRAGRITSLNTDSLTMSANGLITNTIGSTAQGEEGGVIGGNGDTIISAAALINHASITAGHDLSAQIQQQLNNNGGRLAAAQALRLQAATLTNAQGELNADKIAANVTELNNDHGKINASQLTLHATNLSNQQGQLVQFGADASVIDVSKSLDNSNQGFIQTNSADLTLAPQQLNNNGSTISHAGTGTLNVNLRGGTLNNIAGNIGTNGQLLVTAADIANQQGTLHANRNAVITAAGNLTNTQGRVQAAGAVAIQAATIDNSAGRLVSLSTDELSLATSGQIINTAGTTASGEQGGIIGGNGDVIVSADSVLNNSIISAGNNLNATIQRQLDNTGGRVAAANTLQLQAGSLTNAQGVLDATTIHATVAELNNNAGTISTDQLRLYAINLSNQQGQLKQYGTDTSIIDVSNALDNSTNGLIQTNSTNLTLTPQQLNNNGGTISHAGSGTLAINVNNGAGTLQNQAGTIGSNGRVIATASDINNQSGTLFGQSSAHLTATSGDLNNSQQGYISGSLLNVTVAGNIDNTGGKLEGLTNGIDIRANSLNNAAGTIQNLSLSLLNMQLHQNLSNTADSNDDGSVSGFIGSAGDINIEATDIDNTNGSFYSANNLQLNANGTLTNLAGVIQSDGTVDIMATNAINNQSGRIEANGTPGHAATALSLTGNSINNANGRIANSSTGSTVINSNTGINNSAGTIGGNGNVALTAKELINTLQGQLIAAGNMDLAIASSINNVQGNLFSAKNLALQQANATVDNSQGNISSAGDLTLTVASLNNNAGHISNTANQAGNIAISASGNITNTAGNIGSNKNLSITANTIIGEGVAIAGQDADIQLQGDYINTAGNLISANNVLQLSTTGTLSNHGTLSAQNGLLLQANNISNALDALINSDQTVVIAQNNLTNQGRIYGDNLALGATTLLNDKNAVIAARNDLHIGAQTITNQDHALITSLGDTFIGGELNSNYQATGKAKTVTNSQATMDSGGNFIINTTTLNNLNPTFAFAPVVIETKQVVEYAYNRNSAPVEWYNGKLGRCNAVKDDIACLMNDGNHWNLHTPDGRSHSDFWQRIYTQTTSQDQVTATDPGQIVANGNILLRADTINNQASAIVAGLGLGGTGEKLYNTTPIGQTTIQKTGIPNGNGTTDRPGHVFHNTDRKADNWGNFAEINLPEAGPSVEFSIWPGDVAPKRLSNPATGQQAGSNQVATGTSGSLSSNANSTTLTGSGLQVDAAHGSASNNTLTGQGGNIEAATGSAGSNASTPGNTQTVAKPDAAIPNLTLPTNQLFPTTTNPNAGYLVETDPAFTNYKNFLSSDYLLGRLSINPQQAQKRLGDGFYEQKLINDQITQLTGKRFLGNYASNEQQYQALMTEGIHFAEQFQLVVGIALSSEQMSALTSDIVWLVSQNITLADGSRTQVLVPVVYLAQLNAADVRPTGAIISASDMDLSYSGSLQNSGTLQANKNLIVNTGSITNSGNLLTNKQGGQIVLAAQQDISSSGTIQGNRVGIIAGNNINLASVTQTSTGTSGRHTGITQIASVNAEQLVMQAAQNININAANITSTGNASIVAGNNLNIGTVNIGSSFNADMGSTGHYKTSQSSDVGSTLQSGGNLTLAAGQDINATASYVNTDGQLNATAGRDITITSGTQQSSYDIEVHTKSSGFLSSSSRDVTDKGSSTQAIGSSFSGDSVALQSGRDTTIQGSHLTVKQDIAIQAGRDLSIASAQETNQASYSVQEKSSGLSASFMNGISYSKTAQDQAQHGTSTQQVGSSLSGANVRTVSGRDTSITASAIVADHDVDIYAGRDINVLAATEQHTSQTGSHSSGTSIGIMNGLNAGRFTNYSKTDAMQNANGTATQQSTSLISANGGTLNLQAGLDSQYKGTGTGNVLTQGTELLAKNPVNITGNAVDLQAVHNASSSQTHAETKSVTLGSSLTGAIGGAITRIGDQVTEAQNTDNDRLKGALALKAGYDTYKLINGGKISETTTESLSPNPEKSGGGFGVSVNLGVSKSQQDSNNSTTQARGTTVQGGEINITAREGDITMEGAKLQATTIELDAAKNINLLAAKNSAELQSSNSGSSAGIGATLGSNGQQTGLSFQISGSTSKGHANGSETTYDNTQITATDKLTIKSGNNTNLIGAQVAANKVKADISGNLNIVTLQDQSNYDSKQENGGFSLSLCIPPICVGTTATGSINYGKQTVDHNYQSAVGQSGIAAGSGGFELNVKGNTDLQGAAITSTAAADKNSLQTASLTSTDLSNTQHTSSQSISVGISTGSITSNIASNVIGNLNGGAGMPKNGDESSHTNSVISPANVIITGTGNATTDAQSHAIADELTNRDAATANETLTNTLTLQQAQNLQAEQKKARENQRAADLAGAALNGMVGDFSQKMNLAEGSTEKIALHGMVGLIQAGIGGTSAVGGIAAGMSVEVMTPALRDYLLANGYTDDPKNPDGLKAYNDMMNLGATLVGAASGAIAGGSQQSAGTGAVIGLSADANNRQLHQAETDMIKKNAARFAKELYSTDNPTQEQVAAATSVLANTAQNLLDYNFGYTVPYSAQAEAFLHTLQSEYAVTSPNLSIGNGQYLFYATNDQKNSPYINSGTIDKEIAGVIIKAPIKLSETPGSAKEKRDPATNLVLDDEGRYSQRISVDGKTFEPKYFPCPRVSAGCGGQNLDMSDPQTAAYVKALDKKALTDIGTGATLVAVAVPVGTAGAVAGVIGISASVSAGIINETSGTAVSKEIVQMAAQKYLETVFGLPAAAAVRIAALIDLAGGWDAFVTRTKEEALEKKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSE0</accession>
    <name>A0A2S9GSE0_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">ATP synthase subunit b</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">ATP synthase F(0) sector subunit b</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">ATPase subunit I</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">F-type ATPase subunit b</fullName>
            <shortName evidence="13">F-ATPase subunit b</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">atpF</name>
        <name evidence="16" type="ORF">S2091_4650</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.</text>
    </comment>
    <comment type="function">
        <text evidence="11 13">F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="13">F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="13">Cell membrane</location>
            <topology evidence="13">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13 14">Belongs to the ATPase B chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000041">
        <property type="protein sequence ID" value="PRC90642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90642">
        <property type="protein sequence ID" value="PRC90642"/>
        <property type="gene ID" value="S2091_4650"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045263">
        <property type="term" value="C:proton-transporting ATP synthase complex, coupling factor F(o)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01398">
        <property type="entry name" value="ATP_synth_b_bprime"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028987">
        <property type="entry name" value="ATP_synth_B-like_membr_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002146">
        <property type="entry name" value="ATP_synth_b/b'su_bac/chlpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005864">
        <property type="entry name" value="ATP_synth_F0_bsu_bac"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00430">
        <property type="entry name" value="ATP-synt_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81573">
        <property type="entry name" value="SSF81573"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01144">
        <property type="entry name" value="ATP_synt_b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 13" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="13" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 13 14" id="KW-0138">CF(0)</keyword>
    <keyword evidence="15" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6 13 14" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="8 13 14" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 13 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 13 14" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="15">
        <location>
            <begin position="44"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="15">
        <location>
            <begin position="99"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00025198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00025614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01398"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU003848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="PRC90642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="156" mass="17147" checksum="D2F36CE550347B01" modified="2018-07-18" version="1">MNLNSTFIVQFVVFFILAGFTMKFIWPPMMKALDERAQKIAEGLAAAERSKADLKAAEKRVQAELAGARDEGQKHIADAEKRAQLIVDEAKHTASEEAARIVANAKADAEQQVTKARDELRDQVASLAVKGAEQILKREINASVHADLLSHLKAEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSL5</accession>
    <name>A0A2S9GSL5_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SnoaL-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4579</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000038">
        <property type="protein sequence ID" value="PRC90686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90686">
        <property type="protein sequence ID" value="PRC90686"/>
        <property type="gene ID" value="S2091_4579"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037401">
        <property type="entry name" value="SnoaL-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008317">
        <property type="entry name" value="UCP030561"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12680">
        <property type="entry name" value="SnoaL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF030561">
        <property type="entry name" value="UCP030561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SnoaL-like" evidence="1">
        <location>
            <begin position="11"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="122" mass="13646" checksum="09318CE08813FC6C" modified="2018-07-18" version="1">MSIATATSLIQEQLDAYNAKDLERWLATYAPDAEQYTLHGECFARGHAEMRTRIAARFLEPDLHAKLINRTVMGNIVVDLEVITRNFPEGLGTVEMLCIYEVVNGLIQKASFSMGSAKLDVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSZ3</accession>
    <name>A0A2S9GSZ3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">von Willebrand factor type A domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4496</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000035">
        <property type="protein sequence ID" value="PRC90833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90833">
        <property type="protein sequence ID" value="PRC90833"/>
        <property type="gene ID" value="S2091_4496"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041176">
        <property type="entry name" value="VWA_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13519">
        <property type="entry name" value="VWA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18571">
        <property type="entry name" value="VWA_3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="SSF53300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VWFA" evidence="1">
        <location>
            <begin position="40"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="428" mass="46229" checksum="5FEC25519010FD72" modified="2018-07-18" version="1">MFTIEGFYNPYLAASQTRLDAVLTITSDATVSQTTSGRKVVGFVLDTSGSMNGEKLAQAKLAARRGIDMLTEDIWFFVIKFAGSADIVVEACPATSTNKALAHYAVQQLTATGSTAMSSGLKKALGEVKRSGATIASVYFQTDGDNSADDNERYLAGVIAECEGVFQCDCRGIGTDWKPNELRRISSALLGTADAITDPTGLEEDFRSFLNRSLAKGIAAATLRIWSPKVVKVSLVKQMSPEILDLMPSAKRIDDKTLEIPLGAWATEARDYQLAFELPVGNIGDEVLACRAAVVFQDSNGEVKIPCEPIAVRWSEDDALTTRISREVAHYTGQKELADSIQEGLDAKAKGDDDRATRLLGHAAKLAAESGNEEVTRRLKKVVDVVDASAGTVRLKKADKGADMELEMGLTRTVRRNPKQQQAVETQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GT00</accession>
    <name>A0A2S9GT00_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Smr domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4433</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000034">
        <property type="protein sequence ID" value="PRC90852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90852">
        <property type="protein sequence ID" value="PRC90852"/>
        <property type="gene ID" value="S2091_4433"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002625">
        <property type="entry name" value="Smr_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036063">
        <property type="entry name" value="Smr_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01713">
        <property type="entry name" value="Smr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00463">
        <property type="entry name" value="SMR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160443">
        <property type="entry name" value="SSF160443"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50828">
        <property type="entry name" value="SMR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Smr" evidence="1">
        <location>
            <begin position="137"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="224" mass="25088" checksum="0F7BC9E7EADCEBE1" modified="2018-07-18" version="1">MKRAPIKDLNELSSLRNQLKVRAEQEKVAEQKRQAEQLAAQKEANIFRSNMGAVTPIKAPDVYVHQRASIATKTVTTQPKEITSMAQAMQVMEQWSDEFDASQWQEQDEGLSYACPGSGPDLLRKLRKNQWPAQAFLDLHGLQRDQARTALADFLRRSKQARLRSVCVIHGKGINSRQPAILPDKVRSWLCQSELVQAFCPANASDGGDGALHVLLKMERDLGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GT31</accession>
    <name>A0A2S9GT31_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4442</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000034">
        <property type="protein sequence ID" value="PRC90861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90861">
        <property type="protein sequence ID" value="PRC90861"/>
        <property type="gene ID" value="S2091_4442"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC90861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="72" mass="8021" checksum="FA84E43E798D7A26" modified="2018-07-18" version="1">MSDIADRSDKIIHAEIAAGLARVHAAPVLAFTGCCRYCEEAVAEPSRFCNVECRDDFEREMVGLRRAGNCRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTV5</accession>
    <name>A0A2S9GTV5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative acyl-CoA transferases/carnitine dehydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4140</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000028">
        <property type="protein sequence ID" value="PRC91139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91139">
        <property type="protein sequence ID" value="PRC91139"/>
        <property type="gene ID" value="S2091_4140"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10540">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003673">
        <property type="entry name" value="CoA-Trfase_fam_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044855">
        <property type="entry name" value="CoA-Trfase_III_dom3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023606">
        <property type="entry name" value="CoA-Trfase_III_dom_1_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02515">
        <property type="entry name" value="CoA_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89796">
        <property type="entry name" value="SSF89796"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="377" mass="39676" checksum="43C6ECB5F011886E" modified="2018-07-18" version="1">MGVLDGIRIIEIAGIGPGPFCGMLLADMGAEVILIERPSSNKNDPLALGKNAIVNRGKKSLALDLKDPASIAAVLQLISDADALIEGMRPGVMERLGLGPEICLNANPRLVYGRMTGWGQSGPLAQAAGHDINYIALSGALWFSGTPGSAPMAPPTLVGDLGGGALYLAMGILAGILNAKRSGTGQIVDAAIVDGSANLMNLLLSAHAAGQQPFERGRGLLDGPHWYGSYVCADGHCISIGALEPQFNALLFNKLGLGEDADFKSPYDPRLWGRLRERLTALFMQQPRQHWVELLEGSDACFAPVLNPREAMAHPHSQARGIYAEHNGVLQAAPAPRFSATPASAIGAVPKCGEHSVEILRSIGLSEGEIKRLIPEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GU39</accession>
    <name>A0A2S9GU39_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">CheW-like domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_4071</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000027">
        <property type="protein sequence ID" value="PRC91176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91176">
        <property type="protein sequence ID" value="PRC91176"/>
        <property type="gene ID" value="S2091_4071"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024181">
        <property type="entry name" value="Chemotax_regulator_CheV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036061">
        <property type="entry name" value="CheW-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002545">
        <property type="entry name" value="CheW-lke_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01584">
        <property type="entry name" value="CheW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002867">
        <property type="entry name" value="CheV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00260">
        <property type="entry name" value="CheW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50341">
        <property type="entry name" value="SSF50341"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50851">
        <property type="entry name" value="CHEW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CheW-like" evidence="3">
        <location>
            <begin position="19"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="187"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC91176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="323" mass="35034" checksum="B859705FBA0EABC4" modified="2018-07-18" version="1">MSSIQQEIDERTNLTASNKFELLLFRLGVAKHTSHAELFGINVFKVREIVAMPSITEVAGAVENMLGVVNLRGQIIPVIDLPTVVGCVPSSGLNILLVTEYARSTQGFAVESVEEIVRLDWGQVLSAESSSVAGMVTSIARLDGDIANTRLAQVLDVEQILRSIQPEEPEIDAKTVGPTLLLPPGTLILAADDSHMARTLIERGLTAMGAPFIMTKTGKECWEKLQALSNELEAQGKTIHDKVALVLTDLEMPEMDGFTLTRKIKHDTRFQSLPVVIHSSLTGSTNEEHVKNVGADAYVAKFVAEELAATIRKVLSDARIKAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUH6</accession>
    <name>A0A2S9GUH6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Response regulator receiver domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_3903</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000024">
        <property type="protein sequence ID" value="PRC91358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91358">
        <property type="protein sequence ID" value="PRC91358"/>
        <property type="gene ID" value="S2091_3903"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="3">
        <location>
            <begin position="3"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC91358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="236" mass="26867" checksum="8778065A8C4B8501" modified="2018-07-18" version="1">MLKVAVIEDDLPTSNQLKSWIEAAKPGIKIDQWHTRDEAEAAISREKYDLIVLDIELGRERHAGVAIINAINKHHATPVLVVSAMPATIYRSIMKALDAWDYLQKATFEEADFIDTFLEMLRSVKERKQQIDKPAAAADELSMDPLRQRSPIWRGQRINLPLTAQRILAALFASRGQVVSYDELFQVVKSGRNRDNIRKHVSTIREAFREIDANFECIENVPMRGFRWVDSANGGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUJ3</accession>
    <name>A0A2S9GUJ3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3916</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000024">
        <property type="protein sequence ID" value="PRC91371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91371">
        <property type="protein sequence ID" value="PRC91371"/>
        <property type="gene ID" value="S2091_3916"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="79"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="111" mass="13168" checksum="6280F7B986F18A5B" modified="2018-07-18" version="1">MCYPCLDTPVTYVPRLNTSPKKVTQKRRPHYFGNPDFSQEKWEKFETRLRLRQRTFLIHFPCEKPAELEVGASQKQLQNQIQKQLQHQHQHTQTTTSAVQELRPPPTIQQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUQ3</accession>
    <name>A0A2S9GUQ3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">S2091_3843</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ElaB/YgaM/YqjD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000023">
        <property type="protein sequence ID" value="PRC91428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91428">
        <property type="protein sequence ID" value="PRC91428"/>
        <property type="gene ID" value="S2091_3843"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043605">
        <property type="entry name" value="DUF883_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043604">
        <property type="entry name" value="DUF883_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010279">
        <property type="entry name" value="YqjD/ElaB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35893">
        <property type="entry name" value="PTHR35893"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05957">
        <property type="entry name" value="DUF883"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19029">
        <property type="entry name" value="DUF883_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="DUF883" evidence="9">
        <location>
            <begin position="11"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="domain" description="DUF883_C" evidence="10">
        <location>
            <begin position="71"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004377"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF05957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF19029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC91428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="100" mass="10932" checksum="A3F9B57F8D74E441" modified="2018-07-18" version="1">MLEENIHMVNQDIRTLIIDAQALLQAATTLSGEKAEEMRKHGMQLLDTAMAKARDTQINAINTSKRMAASADGYVRENPWRTIATGAGIGLLLGVILGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUS4</accession>
    <name>A0A2S9GUS4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">TPR repeat</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3763</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000022">
        <property type="protein sequence ID" value="PRC91485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91485">
        <property type="protein sequence ID" value="PRC91485"/>
        <property type="gene ID" value="S2091_3763"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004027">
        <property type="entry name" value="SEC_C_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02810">
        <property type="entry name" value="SEC-C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="45"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="79"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="116"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="150"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="184"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="609" mass="68882" checksum="53E778236D1D6416" modified="2018-07-18" version="1">MNKPGRNDPCFCGSKKKFKHCCMQPSLEKREISPSLNRLSDIAALPALLEVANKERLEGKLQEALAHYDAILRLNPNEPEALHFSGMISFQAEEYAKAEQLVRRSIASNPTNISNSYYLVNLSLILKAQSKFQEAVECQLKAIELQPDNAFAYLNLGVTLVAMGRDDEAIENYRKAIALNPDFKEAFYNLGIALRLQGDHIGAIQCNQRVLELDPTYVDAYINLSSSNIVLKNFDAVSAYSLKAIALNPAHFNSYYNLGIACHEQGNLTGSLVFFDHGASLNPNYMNLHCARSLVMLALGNFDQGWKGYEFRWYQENQPEPMRHYPYPWWLGESLQDKTIFVWGEQGIGDQMMFSSMLEELIPLVKHCIFACTKKVIPLFSRSFPKAQVIDLEDASQLASLHHTIDVQSALGSMARWLRPTLERFPHKPYFLKPDQDRVLYWKARLAELGPELKVGICWRSGNISGDRIFYCTQIEQWGPIFSVPGVTFVNLQYDECSLELAQAKEQFGIEVHAFSEVDLYDDIDETAALNKALDLVISAPTSASILSGALGVPTWQMVSGFNWQLMGTSENCWYSSLKTIHRNWDQPWELIMENIAVLLKQQVAQHNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GV09</accession>
    <name>A0A2S9GV09_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">FMN dependent NADH:quinone oxidoreductase</fullName>
            <ecNumber evidence="6">1.6.5.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Azo-dye reductase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">FMN-dependent NADH-azo compound oxidoreductase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">FMN-dependent NADH-azoreductase</fullName>
            <ecNumber evidence="6">1.7.1.17</ecNumber>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">azoR</name>
        <name evidence="8" type="ORF">S2091_3816</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.</text>
    </comment>
    <comment type="function">
        <text evidence="6">Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>2 a quinone + H(+) + NADH = 2 a 1,4-benzosemiquinone + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:65952"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="ChEBI" id="CHEBI:134225"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>anthranilate + N,N-dimethyl-1,4-phenylenediamine + 2 NAD(+) = 2-(4-dimethylaminophenyl)diazenylbenzoate + 2 H(+) + 2 NADH</text>
            <dbReference type="Rhea" id="RHEA:55872"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15783"/>
            <dbReference type="ChEBI" id="CHEBI:16567"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:71579"/>
            <dbReference type="EC" id="1.7.1.17"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="5">
            <dbReference type="Rhea" id="RHEA:55874"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
        <text evidence="6">Binds 1 FMN per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the azoreductase type 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.6.5.-" evidence="6"/>
    <dbReference type="EC" id="1.7.1.17" evidence="6"/>
    <dbReference type="EMBL" id="PUGF01000022">
        <property type="protein sequence ID" value="PRC91538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91538">
        <property type="protein sequence ID" value="PRC91538"/>
        <property type="gene ID" value="S2091_3816"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016652">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016655">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01216">
        <property type="entry name" value="Azoreductase_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003680">
        <property type="entry name" value="Flavodoxin_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023048">
        <property type="entry name" value="NADH:quinone_OxRdtase_FMN_depd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02525">
        <property type="entry name" value="Flavodoxin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="SSF52218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2 6" id="KW-0288">FMN</keyword>
    <keyword evidence="4 6" id="KW-0520">NAD</keyword>
    <keyword evidence="3 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavodoxin_2" evidence="7">
        <location>
            <begin position="3"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="10"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="140"/>
            <end position="143"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01216"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC91538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="204" mass="21886" checksum="C44479AA4875A492" modified="2018-07-18" version="1">MKTLLQLNTSLFSNQGQSSLLANRFVAAWQADHADGKVVVRDMATDPVPHLDGERFSAFLSKPESRTAEQQAIVAYSDSLINELKNADVLVLGLPLYNFGVPSVLKAYIDHIARAGSTFSYTAQGPVGLVTGKKALIFATRGGQYAGTAMDTQTDYVRGFLAFIGITDVEFVYAEGLAMGDEGKQVAITKAHEKIAELNLALAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GV17</accession>
    <name>A0A2S9GV17_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">1-deoxy-D-xylulose-5-phosphate synthase</fullName>
            <ecNumber evidence="10">2.2.1.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">1-deoxyxylulose-5-phosphate synthase</fullName>
            <shortName evidence="10">DXP synthase</shortName>
            <shortName evidence="10">DXPS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">dxs</name>
        <name evidence="12" type="ORF">S2091_3670</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>D-glyceraldehyde 3-phosphate + H(+) + pyruvate = 1-deoxy-D-xylulose 5-phosphate + CO2</text>
            <dbReference type="Rhea" id="RHEA:12605"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57792"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="2.2.1.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="10">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
        <text evidence="10">Binds 1 thiamine pyrophosphate per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 10">Metabolic intermediate biosynthesis; 1-deoxy-D-xylulose 5-phosphate biosynthesis; 1-deoxy-D-xylulose 5-phosphate from D-glyceraldehyde 3-phosphate and pyruvate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 10">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the transketolase family. DXPS subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.2.1.7" evidence="10"/>
    <dbReference type="EMBL" id="PUGF01000021">
        <property type="protein sequence ID" value="PRC91554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91554">
        <property type="protein sequence ID" value="PRC91554"/>
        <property type="gene ID" value="S2091_3670"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00064">
        <property type="reaction ID" value="UER00091"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008661">
        <property type="term" value="F:1-deoxy-D-xylulose-5-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052865">
        <property type="term" value="P:1-deoxy-D-xylulose 5-phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016114">
        <property type="term" value="P:terpenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009228">
        <property type="term" value="P:thiamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02007">
        <property type="entry name" value="TPP_DXS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00315">
        <property type="entry name" value="DXP_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005477">
        <property type="entry name" value="Dxylulose-5-P_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005475">
        <property type="entry name" value="Transketolase-like_Pyr-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020826">
        <property type="entry name" value="Transketolase_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033248">
        <property type="entry name" value="Transketolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005474">
        <property type="entry name" value="Transketolase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43322">
        <property type="entry name" value="PTHR43322"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13292">
        <property type="entry name" value="DXP_synthase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02779">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02780">
        <property type="entry name" value="Transketolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00861">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="SSF52922"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00204">
        <property type="entry name" value="dxs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00801">
        <property type="entry name" value="TRANSKETOLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00802">
        <property type="entry name" value="TRANSKETOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword evidence="6 10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0784">Thiamine biosynthesis</keyword>
    <keyword evidence="8 10" id="KW-0786">Thiamine pyrophosphate</keyword>
    <keyword evidence="4 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TRANSKETOLASE_1" evidence="11">
        <location>
            <begin position="29"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Thiamine pyrophosphate binding" evidence="10">
        <location>
            <begin position="114"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Thiamine pyrophosphate binding" evidence="10">
        <location>
            <begin position="146"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="73"/>
        </location>
        <ligand>
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="145"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="175"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="280"/>
        </location>
        <ligand>
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="361"/>
        </location>
        <ligand>
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS00801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PRC91554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="628" mass="67677" checksum="06E77BB8EFB841DB" modified="2018-07-18" version="1">MTLLKDINSPADLRHLSRAQLKPLADELRAFVLDSVSKTGGHLSSNLGTVELTIALHYVFNTPDDRLVWDVGHQTYPHKILTGRRDQMHSLRQFNGISGFPKRDESEFDTFGTAHSSTSISAALGMAVAAKIKGENRHSVAIIGDGSMTAGMAFEALNNAGVMEDVNLLVILNDNDMSISPPVGALNRYLARLMSGKFYAAARNVGKSVLPPPMLEIAKRLEEHAKGMIMPATLFEEFGFNYIGPIDGHDLEALIPTLQNLKELKGPQFLHVVTKKGQGYKLAEADPVLYHGPGKFNPAEGIKPATAPKLTYTKVFGDWLCDMAEQDKRLVGITPAMREGSGMVEFEQQYPSRYYDVGIAEQHSVTFAAGLACEGLKPVVAIYSTFLQRAYDQLIHDVALQNLDVTFALDRAGLVGADGATHAGNYDLAYLRCIPNMVIMAASDENECRQMLTTGFQYNGPAAIRYPRGAGIGAEVKKELTTIPLGTGEVKRQGKRIAIFAFGSMVAPALQAAEKLNATVANMRFIKPLDVALVKQLAESHDILVSVEEGAKMGGAGSAIAEALAELGINKSVLILGLPDQFIDHGEAGQLLALCGLDGVGISNSIQGHYHLAEATTVVEPRLVSNSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GV68</accession>
    <name>A0A2S9GV68_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Sss: transporter, solute:sodium symporter (SSS) family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">S2091_3733</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000021">
        <property type="protein sequence ID" value="PRC91617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91617">
        <property type="protein sequence ID" value="PRC91617"/>
        <property type="gene ID" value="S2091_3733"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015293">
        <property type="term" value="F:symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006814">
        <property type="term" value="P:sodium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1730.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038377">
        <property type="entry name" value="Na/Glc_symporter_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001734">
        <property type="entry name" value="Na/solute_symporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018212">
        <property type="entry name" value="Na/solute_symporter_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00474">
        <property type="entry name" value="SSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00813">
        <property type="entry name" value="sss"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00456">
        <property type="entry name" value="NA_SOLUT_SYMP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50283">
        <property type="entry name" value="NA_SOLUT_SYMP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <keyword evidence="7" id="KW-0915">Sodium</keyword>
    <keyword evidence="7" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="4" id="KW-0769">Symport</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015642162" evidence="10">
        <location>
            <begin position="23"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="38"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="79"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="108"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="152"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="185"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="216"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="292"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="328"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="385"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="435"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="460"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="491"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="530"/>
            <end position="548"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC91617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="580" mass="61395" checksum="57081B53DC6127A9" modified="2018-07-18" version="1">MKLIKMLVTAFTLTAMHGAVWAAGPDLGQAAKQPTNWVAIAMFAVFVILTLFITKWAANRTKSAADFYTAGGGITGFQNGLAIAGDYMSAASFLGISAAVYLNGYDGLIYSVGFLVGWPVITFLMAERLRNLGRYTFADVAAYRFQQKPIRIFAASGTLAVVVFYLIAQMVGAGQLIKLLFGLEYWIAVAIVGTLMLIYVLFGGMTATTWVQIIKACLLLAGASFMAFMVLAQFNFSPEALFAKAIEVKTSLAMHDPKLIVDAAAKGVSPEALAATKGVSIMGPGNFVKDPISAISFGMALMFGTAGLPHILMRFFTVPSAKEARKSVFWATTWIGYFYILTFIIGFGAIVLVSTNPDFKTAAGQLLGGDNMAAVHLAKAVGGNVFLGFISAVAFATILAVVSGLTLSGASAVSHDLYSTVFKAGKASSADELRVSRMTTIVLGFVAVVLGIVFEKQNVAFMVSLAFAIAASANFPVLFMSVLWKNCTTRGATIGGFIGLVSALGLTVISKSVWVDVLHNKAAIFPYTSPALFSMIAGFVGIWLFSVLDKSPRAAIDRAGYEAQRVRSETGIGAEGSSGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVC1</accession>
    <name>A0A2S9GVC1_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Aminomethyltransferase</fullName>
            <ecNumber evidence="3">2.1.2.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Glycine cleavage system T protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_3586</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(6S)-5,6,7,8-tetrahydrofolate + (R)-N(6)-(S(8)-aminomethyldihydrolipoyl)-L-lysyl-[protein] = (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + (R)-N(6)-dihydrolipoyl-L-lysyl-[protein] + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:16945"/>
            <dbReference type="Rhea" id="RHEA-COMP:10475"/>
            <dbReference type="Rhea" id="RHEA-COMP:10492"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="ChEBI" id="CHEBI:83100"/>
            <dbReference type="ChEBI" id="CHEBI:83143"/>
            <dbReference type="EC" id="2.1.2.10"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GcvT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.10" evidence="3"/>
    <dbReference type="EMBL" id="PUGF01000020">
        <property type="protein sequence ID" value="PRC91648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91648">
        <property type="protein sequence ID" value="PRC91648"/>
        <property type="gene ID" value="S2091_3586"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004047">
        <property type="term" value="F:aminomethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006546">
        <property type="term" value="P:glycine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006223">
        <property type="entry name" value="GCS_T"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028896">
        <property type="entry name" value="GCST/YgfZ/DmdA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013977">
        <property type="entry name" value="GCV_T_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006222">
        <property type="entry name" value="GCV_T_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029043">
        <property type="entry name" value="GcvT/YgfZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027266">
        <property type="entry name" value="TrmE/GcvT_dom1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43757">
        <property type="entry name" value="PTHR43757"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01571">
        <property type="entry name" value="GCV_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08669">
        <property type="entry name" value="GCV_T_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101790">
        <property type="entry name" value="SSF101790"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00528">
        <property type="entry name" value="gcvT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GCV_T" evidence="7">
        <location>
            <begin position="15"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="domain" description="GCV_T_C" evidence="8">
        <location>
            <begin position="297"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00031395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF08669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC91648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="382" mass="40728" checksum="B2FABDF738F0C51B" modified="2018-07-18" version="1">MTNATEATDLLRTPLYDLHLELGARMVPFAGYQMPVQYPLGVMKEHLHTRTAAGLFDVSHMGQVRLSPLAGADVNAVATALETLVPIDVLDLPLNKQRYAVFTNEQGGILDDLMISNMGDSLFVVVNAACKQQDVAHMRKHLEGYCKVEELADRALLALQGPAAAAVMARLLPETEAMVFMDSKEVTLVGVSCFISRSGYTGEDGFEISVPNQKAEELARLLLAQPEVAAIGLGARDSLRLEAGLCLYGHDMDATITPVEASLLWALSKVRRADGARAGGYPGAAAIQAHIADGVSKKRVGLQINEKIPVREGAEIVDAEGTVIGKVTSGGFGPSVNAPVAMGYVSLPFAAIGTKLQAIVRGKPVAVEVVKTPFFAQRYHRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVI0</accession>
    <name>A0A2S9GVI0_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Ketol-acid reductoisomerase (NADP(+))</fullName>
            <shortName evidence="9">KARI</shortName>
            <ecNumber evidence="9">1.1.1.86</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Acetohydroxy-acid isomeroreductase</fullName>
            <shortName evidence="9">AHIR</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Alpha-keto-beta-hydroxylacyl reductoisomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">ilvC</name>
        <name evidence="13" type="ORF">S2091_3646</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 9">Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>(2R)-2,3-dihydroxy-3-methylbutanoate + NADP(+) = (2S)-2-acetolactate + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:22068"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:49072"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:58476"/>
            <dbReference type="EC" id="1.1.1.86"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>(2R,3R)-2,3-dihydroxy-3-methylpentanoate + NADP(+) = (S)-2-ethyl-2-hydroxy-3-oxobutanoate + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:13493"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:49256"/>
            <dbReference type="ChEBI" id="CHEBI:49258"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.86"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="9">Binds 2 magnesium ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 9">Amino-acid biosynthesis; L-isoleucine biosynthesis; L-isoleucine from 2-oxobutanoate: step 2/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 9">Amino-acid biosynthesis; L-valine biosynthesis; L-valine from pyruvate: step 2/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 9 10">Belongs to the ketol-acid reductoisomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.86" evidence="9"/>
    <dbReference type="EMBL" id="PUGF01000020">
        <property type="protein sequence ID" value="PRC91708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91708">
        <property type="protein sequence ID" value="PRC91708"/>
        <property type="gene ID" value="S2091_3646"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00047">
        <property type="reaction ID" value="UER00056"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00049">
        <property type="reaction ID" value="UER00060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004455">
        <property type="term" value="F:ketol-acid reductoisomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009099">
        <property type="term" value="P:valine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00435">
        <property type="entry name" value="IlvC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013023">
        <property type="entry name" value="KARI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000506">
        <property type="entry name" value="KARI_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013116">
        <property type="entry name" value="KARI_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014359">
        <property type="entry name" value="KARI_prok"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21371">
        <property type="entry name" value="PTHR21371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01450">
        <property type="entry name" value="IlvC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07991">
        <property type="entry name" value="IlvN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000116">
        <property type="entry name" value="IlvC_gammaproteo"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00465">
        <property type="entry name" value="ilvC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51851">
        <property type="entry name" value="KARI_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51850">
        <property type="entry name" value="KARI_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9 10" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="8 9 10" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="13" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7 9 10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 9 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0521">NADP</keyword>
    <keyword evidence="9 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="KARI N-terminal Rossmann" evidence="11">
        <location>
            <begin position="1"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="domain" description="KARI C-terminal knotted" evidence="12">
        <location>
            <begin position="182"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="107"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="24"/>
            <end position="27"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="47"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="52"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="133"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9 10">
        <location>
            <position position="190"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9 10">
        <location>
            <position position="194"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9 10">
        <location>
            <position position="226"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9 10">
        <location>
            <position position="230"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9 10">
        <location>
            <position position="251"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010318"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PRC91708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="338" mass="36625" checksum="D7008E3246E9BDB3" modified="2018-07-18" version="1">MNVFYDKDCDLSLIKGKNVTIIGYGSQGHAHAQNLNDSGCKVTVALRKDGASWNKAKNAGLNVAEVNEAVKAADVIMILLPDENIAQVYNENVAPHAKQGAVLAFAHGFNVHYGQVVPRADLDVIMIAPKAPGHTVRATYTQGGGVPHLVAVYQDKSGSARDIALSYAMANGGGRAGIIETNFREETETDLFGEQAVLCGGAVELIKAGFETLTEAGYAPEMAYFECLHELKLIVDLIYEGGIANMNYSISNNAEYGEYVTGPKIVTEDTKNAMRKCLKDIQTGEYAKSFILENKAGAPTLISRRRLNSEHQIEQVGAKLRGMMPWIAKNKMVDQSKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVK0</accession>
    <name>A0A2S9GVK0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3483</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000019">
        <property type="protein sequence ID" value="PRC91728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91728">
        <property type="protein sequence ID" value="PRC91728"/>
        <property type="gene ID" value="S2091_3483"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="112" mass="12598" checksum="02F8B8C3F8B4311F" modified="2018-07-18" version="1">MDGYYRSIRSADCFVDSTKSEICQVEQGLNIKHRSKDSYFIWIHTEGNYGHICSYKEIGKLLGSSLVVDKDNCRVVIQVDNDVAKIRVTGESCEANYCGANVDLNVDGLKRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVM2</accession>
    <name>A0A2S9GVM2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Dehydrogenases with different specificities (Related to short-chain alcohol dehydrogenases)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3528</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000019">
        <property type="protein sequence ID" value="PRC91773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91773">
        <property type="protein sequence ID" value="PRC91773"/>
        <property type="gene ID" value="S2091_3528"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="252" mass="26507" checksum="4F63CD9FDD3CF3DF" modified="2018-07-18" version="1">MSNKIAIITGGSRGLGKSAALKLAQQGVDVILTYHSKKAEALAVVAEIESYGGQAAALQLDVGNSASFNEFATQVQQLLAEKWQRKDFNFLVNNAGIGIHAGIAETTEAQFDQLVNIQFKGVFFLTQKLLPLIADHGRIINISTGLTRFALPGYAAYGAMKGAIEVLSKYLAKELGARGIAVNVVAPGAIETDFGDGAVRDNSQINSFIASQTALGRVGLPDDIGGVIASLLNDANGWINAQRIEASGGMFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVT4</accession>
    <name>A0A2S9GVT4_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Negative regulator of flagellin synthesis</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Anti-sigma-28 factor</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">S2091_3388</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Responsible for the coupling of flagellin expression to flagellar assembly by preventing expression of the flagellin genes when a component of the middle class of proteins is defective. It negatively regulates flagellar genes by inhibiting the activity of FliA by directly binding to FliA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the FlgM family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000018">
        <property type="protein sequence ID" value="PRC91832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91832">
        <property type="protein sequence ID" value="PRC91832"/>
        <property type="gene ID" value="S2091_3388"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044781">
        <property type="term" value="P:bacterial-type flagellum organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035890">
        <property type="entry name" value="Anti-sigma-28_factor_FlgM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007412">
        <property type="entry name" value="FlgM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031316">
        <property type="entry name" value="FlgM_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04316">
        <property type="entry name" value="FlgM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101498">
        <property type="entry name" value="SSF101498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03824">
        <property type="entry name" value="FlgM_jcvi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1005">Bacterial flagellum biogenesis</keyword>
    <keyword evidence="11" id="KW-0966">Cell projection</keyword>
    <keyword evidence="11" id="KW-0969">Cilium</keyword>
    <keyword evidence="11" id="KW-0282">Flagellum</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0678">Repressor</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="FlgM" evidence="10">
        <location>
            <begin position="62"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="20"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00017823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00030117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF04316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC91832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="124" mass="12261" checksum="0780B1EF5698C2D7" modified="2018-07-18" version="1">MTTITNATTSPPLPPTSSPTVKPNSGASTNDVATSTNNAANTGAAAGTTGAAAGSSSSSVTTISTISTQLQAAQAASSSDAVFSSSKVNEIKQAISEGRFQVNSEKVADGLLDSVNDLLGSRRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVT6</accession>
    <name>A0A2S9GVT6_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF4157 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3391</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000018">
        <property type="protein sequence ID" value="PRC91835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91835">
        <property type="protein sequence ID" value="PRC91835"/>
        <property type="gene ID" value="S2091_3391"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025295">
        <property type="entry name" value="DUF4157"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13699">
        <property type="entry name" value="DUF4157"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4157" evidence="2">
        <location>
            <begin position="125"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="95"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="374"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="533" mass="59429" checksum="8A834F685DA81463" modified="2018-07-18" version="1">MSTAVPVQQAKTDSPQRNTQLAKQNSNKLAEGMQSKFADNRPQATAQRNLQNVANNSHQSRQLQAVSRMAQSSAQAIQLKATNTLTNASALQRVEEEEPLQAKSVESGTAQRAEQAAQKLNNTGLPDNLKSGIEALSGMSMDHVKVHYNSPQPAQLNAHAYAQGSEIHVAPQQEKHLPHEAWHVVQQAQGRVKPTMQMKLDVAVNDDVGLEAEADVMGAKALASAQLVQKNETRMFASAQVSAQAKTSTAPQQKANNSAFTPQIKSGMPFQLKWLEYGGKHYAWDQLINETQWFYNKETGQMFYERGGVRSEKKNRTAWLDDNDGNDLLKDEDASIELDVEKRKSIEVIEVAGWDDSLVSEVLEIQREWEVKKKEDGEREKSELGDDRCSMDDWTQTDEGIDVAGDLADEENRKVAGTSDGYLRTFIAHYKKEAEPIAVMMIEMRSSSEMFDTKEHLYLRWLVGSPRRKGGGKQLSDQAKIMAREARRLLVVESAKSATGWYGTQGFVARGDAKHNDEFNDCGCLFMDWQPGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVV0</accession>
    <name>A0A2S9GVV0_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">Basal-body rod modification protein FlgD</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_3384</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4 5">Required for flagellar hook formation. May act as a scaffolding protein.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the FlgD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000018">
        <property type="protein sequence ID" value="PRC91828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91828">
        <property type="protein sequence ID" value="PRC91828"/>
        <property type="gene ID" value="S2091_3384"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044781">
        <property type="term" value="P:bacterial-type flagellum organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005648">
        <property type="entry name" value="FlgD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025965">
        <property type="entry name" value="FlgD_Ig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025963">
        <property type="entry name" value="FLgD_Tudor"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03963">
        <property type="entry name" value="FlgD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13860">
        <property type="entry name" value="FlgD_ig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13861">
        <property type="entry name" value="FLgD_tudor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-1005">Bacterial flagellum biogenesis</keyword>
    <keyword evidence="9" id="KW-0966">Cell projection</keyword>
    <keyword evidence="9" id="KW-0969">Cilium</keyword>
    <keyword evidence="9" id="KW-0282">Flagellum</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FLgD_tudor" evidence="8">
        <location>
            <begin position="100"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="domain" description="FlgD_ig" evidence="7">
        <location>
            <begin position="117"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00024746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF13860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF13861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC91828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="236" mass="23492" checksum="CB054C42662F1ED8" modified="2018-07-18" version="1">MATTINSVSPALLSTMNPTSSSSTSSSTNSTAASSSGTESAATLQNNFMTMLITQMKNQDPLNPMDNAQVTSQMAQLSTVTGVSQLNTTLTSLMANFQSSQTMQAANLIGKSVVVPGNAVTLSSGAGQFGVNLSSAATNVKATITNAAGAVVDTMNLGSMPSGVSAIPWNGTTTTGTTAPDGQYTFTLTANNGATPVTATGLSVGMVSSVSAGASGAQLNIPTIGTTSFSSVLQIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GW02</accession>
    <name>A0A2S9GW02_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein HflC</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_3463</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">HflC and HflK could regulate a protease.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the band 7/mec-2 family. HflC subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000018">
        <property type="protein sequence ID" value="PRC91907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91907">
        <property type="protein sequence ID" value="PRC91907"/>
        <property type="gene ID" value="S2091_3463"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052547">
        <property type="term" value="P:regulation of peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03405">
        <property type="entry name" value="SPFH_HflC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001107">
        <property type="entry name" value="Band_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036013">
        <property type="entry name" value="Band_7/SPFH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010200">
        <property type="entry name" value="HflC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42911">
        <property type="entry name" value="PTHR42911"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01145">
        <property type="entry name" value="Band_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005651">
        <property type="entry name" value="HflC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00244">
        <property type="entry name" value="PHB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117892">
        <property type="entry name" value="SSF117892"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01932">
        <property type="entry name" value="hflC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PHB" evidence="3">
        <location>
            <begin position="20"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR005651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC91907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="291" mass="33024" checksum="458F43BCCD8C9C25" modified="2018-07-18" version="1">MNKLISTGIAVIIALLVFSSTVFVVDQRQFAIVFALGEMKTIISEPGLHFKLPPPFQNVVFLDKRILTIDSPEADRFITAEKKNILVDSFVKWHITDPKLYYVSFGGDEQRAKDRMNQIVKAALNDEITKLTVRDVISGDRSKVMDVLRAKVSLEAKQIGVDIIDVRLKRIDYIDTVNESVYGRMKAERTRVANELRSTGYAESERIRADADKQGTVILAEAYRDAENLRGEGDARASRIYAQAFGQNPEFYKFYRSLEAYRASFKTKNDVLVVDPNSEFFKYFKAPGQGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GW55</accession>
    <name>A0A2S9GW55_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">GGDEF: diguanylate cyclase (GGDEF) domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_3295</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000017">
        <property type="protein sequence ID" value="PRC91953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91953">
        <property type="protein sequence ID" value="PRC91953"/>
        <property type="gene ID" value="S2091_3295"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01948">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001633">
        <property type="entry name" value="EAL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035919">
        <property type="entry name" value="EAL_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013767">
        <property type="entry name" value="PAS_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00563">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00989">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00052">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141868">
        <property type="entry name" value="SSF141868"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50883">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="4"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="3">
        <location>
            <begin position="155"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="4">
        <location>
            <begin position="233"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="6">
        <location>
            <begin position="317"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="domain" description="EAL" evidence="5">
        <location>
            <begin position="464"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC91953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="721" mass="80287" checksum="3D8B005EE85A3DE5" modified="2018-07-18" version="1">MPSKILIVEDESIVALDLQRRLIVLGYEVPRVAASHDQAMKAVNEIMPDIVLMDINISGDIDGIDTAAKINVPVIYLTAYSEEKTLERAKATKPYGYLIKPFSERELHATIQMALERHNVELRLKNNEEQLAIAYANLEVGKRELEVRATELFQEKQRLEVTLNSIGDGVITTDEYGNVTYLNPVAEEKTGWTILEACGQAASKVLVIVNEETQEPNPSPIEAVLRTGKISGMSNHSALIGKHGIMYAIEDSAAPMLDRDNKVIGVVLVFHDVSDARRLSEEMTYQATHDALTDLVNRSEFDRRLQKAIESSSLHGHQHALAYLDLDQFKIVNDTCGHNSGDELLRQITGLLRLTLRANDTLARLGGDEFGVLLESCPPYFALQIAENLRNIIGDFHFVWDEKTFPISVSIGLVNFGGNGPENLSCAEILRIADSACYTAKDLGRNRIHVYMEDDYEMSKRHGEIDWYTKIYSAITQNRFVLYAQKIVSLNTTQPYHEHVEILLRLINTESQIIPPMAFIPAAERYGLMPEIDRWVVRTAFAHIAKLEFGATSLFSINLSGASLNDEKALPFIFEQLETSGVNSGSICFEITETAAITNLLNARAFIIALQSKGCKFALDDFGSGMSSFSYLKHLPVNFLKIDGCFVKDIANDPVDAAMVAAINNIGHVMVLETIAEFVEDKEILKKLREIGVDYAQGYEVGHPVPLSQLDLTAPKKIEQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GW93</accession>
    <name>A0A2S9GW93_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SoxB: sarcosine oxidase, beta subunit family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3310</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000017">
        <property type="protein sequence ID" value="PRC91968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91968">
        <property type="protein sequence ID" value="PRC91968"/>
        <property type="gene ID" value="S2091_3310"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008115">
        <property type="term" value="F:sarcosine oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046653">
        <property type="term" value="P:tetrahydrofolate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006278">
        <property type="entry name" value="SoxB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01373">
        <property type="entry name" value="soxB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rhodanese" evidence="1">
        <location>
            <begin position="37"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="418" mass="45465" checksum="5881EC9C180F3383" modified="2018-07-18" version="1">MAQKNYSLWSLIQQGFKRQEGWDQAWRSPEPKSSYDVIIIGAGGHGLATAYYLAKEHGIRNIAVLEKGYLGGGNTARNTTIVRSNYLWDEAAMLYEHSLKLWEGLSQEINFNVMFSQRGVFNLGHSLQDMRDIERRVNANLINEIDAQVLSAAEVKDRIPMINTSSNTRYPIMGASFQPRAGVARHDAVAWGFARAASNLGVDIIEQCEVTGLNVDGGHIKGVETSRGTIRADRVGCVAAGHSTTLAKMVGLRMPLESHPLQAFVSESLKPVLDTVVMSNAVHGYLSQSDKGELVIGAGIDSYLSYAQRGSPHVIEHTAAAIIELFPMFSRVRMNRQWGGIVDVSPDACPIIGKTPIKGLYFNCGWGTGGFKATPGSGHVFAHTIAHDEPHPLNAAFGLDRFHSGHLIDEHGAAGVAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWC2</accession>
    <name>A0A2S9GWC2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">NADH(P)-binding</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3356</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000017">
        <property type="protein sequence ID" value="PRC92014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92014">
        <property type="protein sequence ID" value="PRC92014"/>
        <property type="gene ID" value="S2091_3356"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="297" mass="32555" checksum="C1DE51CCBF6B0B5F" modified="2018-07-18" version="1">MKKNQKCKKIGLPRVLIVGCGDIGMRILPLLGAHFRVFAVTSQASRCEELRAAGAIPLIANLDEPATLARLAGLASLIIYLAPPPSEGVSDTRSRHLAALLSRRCCLVYVSTSGVYGDCGGALIAETRTVKPHNLRAVRRVDAEQVWRLWARRTGSALSILRVPGIYAADRLPLERLKKGLPALLPEQDVFTNHIHADDLARLVMQALFYGSPNRVYHAVDDSCLLMGEYFDLVADRVGLPRVPRLARDELVLQVSPAMLSFMGESRRMSNLRIKGELGFRLRYPSVVDGVVGIGVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWI3</accession>
    <name>A0A2S9GWI3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3193</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000016">
        <property type="protein sequence ID" value="PRC92058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92058">
        <property type="protein sequence ID" value="PRC92058"/>
        <property type="gene ID" value="S2091_3193"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="1">
        <location>
            <begin position="49"/>
            <end position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="399" mass="43926" checksum="30527C4044DFC4E3" modified="2018-07-18" version="1">MKLDNLTPIEWKFSERAEQLQSSMIREILKITQRPEVISFAGGLPSPETFPVERMRAAFDKVLSTSGKSALQYGPTDGYAPLREFIANSLSTNGAKISPDQVLMVSGSQQGLDLLGKVLLDEGSKALVETPSYLGALQAFSVYRPEFVSVEMDEHGLLPSAVAAKGEGARLLYSLPNFQNPTGLTLSTERRIELVETCARMRIPLLEDDPYGALCYRGEPLPKMLNMNPDGVIYMGSFSKVLTPGIRLGYVVAPHKLIRKLEQAKQAADLHTAQLTQMVVYEVIKDGFLDEHIPTIRTFYSGQCDIMLDALSKHFPAGVTWTKPDGGMFIWVKLPQHIDSMALSTEAIAQNVAFVPGVPFYAGVPETNTLRLSFVTVSPERIYEGIEKLGKLIASKLSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWQ1</accession>
    <name>A0A2S9GWQ1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Beta-lactamase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3056</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92140">
        <property type="protein sequence ID" value="PRC92140"/>
        <property type="gene ID" value="S2091_3056"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta-lactamase" evidence="1">
        <location>
            <begin position="47"/>
            <end position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="398" mass="41374" checksum="7404E4D64DEA55CB" modified="2018-07-18" version="1">MQFFVKDIFKQIYTCTIVVFLGACGGGGGSSTATTPTQPVSLSATVDGIMSSTMASTGVTAATVTIMHNGVVLHDKGYGFLDAAGTIPLPASALMVTASIVKPVTASAIQTLASNGTLALSDHVFCTGSNTPCWLSADLLSSSTDPRVANITIQQLIAHEGGWDISQHGNVDFDKLESVVQSSLALSTPPAQTDDIRYWMAKPLDFTPGARAAYTNFGYLLLGRIIAQASNTSYLQYLQNTILRPLGVASADFSGAASLLADRNPREPNYITSIMAPSIFAPGTTVICTNGAINTLNWVSATTSITTSKAMATFAGSYLIQTNADGTDEAQDGIPLAGKTNDGFHFGNYPGTSAIIRQLPSGVSYAVLMNKSNETGSVGYQGSLMTSIDAAIAAAGLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWQ7</accession>
    <name>A0A2S9GWQ7_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 7">ATP-dependent Clp protease proteolytic subunit</fullName>
            <ecNumber evidence="5">3.4.21.92</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Endopeptidase Clp</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">clpP</name>
        <name evidence="8" type="ORF">S2091_3047</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 7">Belongs to the peptidase S14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.92" evidence="5"/>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92131">
        <property type="protein sequence ID" value="PRC92131"/>
        <property type="gene ID" value="S2091_3047"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07017">
        <property type="entry name" value="S14_ClpP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00444">
        <property type="entry name" value="ClpP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001907">
        <property type="entry name" value="ClpP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023562">
        <property type="entry name" value="ClpP/TepA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033135">
        <property type="entry name" value="ClpP_His_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10381">
        <property type="entry name" value="PTHR10381"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00574">
        <property type="entry name" value="CLP_protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00127">
        <property type="entry name" value="CLPPROTEASEP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00493">
        <property type="entry name" value="clpP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00382">
        <property type="entry name" value="CLP_PROTEASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0720">Serine protease</keyword>
    <feature type="active site" description="Nucleophile" evidence="5">
        <location>
            <position position="112"/>
        </location>
    </feature>
    <feature type="active site" evidence="5 6">
        <location>
            <position position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC92131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="208" mass="22734" checksum="A8F7EA9D85FCD927" modified="2018-07-18" version="1">MTSLIRNSALNTEMLGMVPMVIEQSGRGERSYDIYSRLLKERVIFLVGPVNDQTANLVVAQLLFLESENPDKDISFYINSPGGSVSAGLAIYDTMQFIKPDVSTLCTGMAASMGAFLLAAGAKGKRFSLPNSRIMIHQPLGGAQGQASDIEIQAREILYLRERLNEMLATHTGKTAEQIGKDTDRDNFMSAADAVEYGLIDKVMAHRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWS7</accession>
    <name>A0A2S9GWS7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Crp-like helix-turn-helix domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3088</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92172">
        <property type="protein sequence ID" value="PRC92172"/>
        <property type="gene ID" value="S2091_3088"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012318">
        <property type="entry name" value="HTH_CRP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13545">
        <property type="entry name" value="HTH_Crp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00419">
        <property type="entry name" value="HTH_CRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="SSF51206"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51063">
        <property type="entry name" value="HTH_CRP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH crp-type" evidence="2">
        <location>
            <begin position="146"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="254" mass="28219" checksum="9128CA72BE525AF2" modified="2018-07-18" version="1">MPSLHDPNQNQLLAALLDAEFDRISPHLELVQMKLGDLLYESGGKLQHVYFPTTSIISLHYVLENGSSSEIAGVGNEGVLGVSLFMGGNTTPSRAIVQTGGYGYRLKSQLLLEEFNRAGAVMRLLLRYTQALITQMSQTAVCNRHHSVEQQLCRWLLLTLDRMPTNELTMTQELIASMLGVRREGVTEAAGKLQSYGFISYRRGHITVTDRAGLERNVCECYGVVKKEFARLLSDVRQRQTSSSNNSGGQQQAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWU3</accession>
    <name>A0A2S9GWU3_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 10">Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex</fullName>
            <ecNumber evidence="5 10">2.3.1.61</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">2-oxoglutarate dehydrogenase complex component E2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">S2091_3105</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 10">E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>(R)-N(6)-dihydrolipoyl-L-lysyl-[2-oxoglutarate dehydrogenase complex component E2] + succinyl-CoA = (R)-N(6)-(S(8)-succinyldihydrolipoyl)-L-lysyl-[2-oxoglutarate dehydrogenase complex component E2] + CoA</text>
            <dbReference type="Rhea" id="RHEA:15213"/>
            <dbReference type="Rhea" id="RHEA-COMP:10581"/>
            <dbReference type="Rhea" id="RHEA-COMP:10582"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57292"/>
            <dbReference type="ChEBI" id="CHEBI:83100"/>
            <dbReference type="ChEBI" id="CHEBI:83120"/>
            <dbReference type="EC" id="2.3.1.61"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>(R)-lipoate</name>
            <dbReference type="ChEBI" id="CHEBI:83088"/>
        </cofactor>
        <text evidence="10">Binds 1 lipoyl cofactor covalently.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 10">Amino-acid degradation; L-lysine degradation via saccharopine pathway; glutaryl-CoA from L-lysine: step 6/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the 2-oxoacid dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.61" evidence="5 10"/>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92189">
        <property type="protein sequence ID" value="PRC92189"/>
        <property type="gene ID" value="S2091_3105"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00868">
        <property type="reaction ID" value="UER00840"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045252">
        <property type="term" value="C:oxoglutarate dehydrogenase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004149">
        <property type="term" value="F:dihydrolipoyllysine-residue succinyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033512">
        <property type="term" value="P:L-lysine catabolic process to acetyl-CoA via saccharopine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.320.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003016">
        <property type="entry name" value="2-oxoA_DH_lipoyl-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001078">
        <property type="entry name" value="2-oxoacid_DH_actylTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036625">
        <property type="entry name" value="E3-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004167">
        <property type="entry name" value="PSBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006255">
        <property type="entry name" value="SucB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00198">
        <property type="entry name" value="2-oxoacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02817">
        <property type="entry name" value="E3_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47005">
        <property type="entry name" value="SSF47005"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="SSF51230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01347">
        <property type="entry name" value="sucB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00189">
        <property type="entry name" value="LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51826">
        <property type="entry name" value="PSBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="9 10" id="KW-0450">Lipoyl</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 10 13" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 10" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="11">
        <location>
            <begin position="3"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="domain" description="Peripheral subunit-binding (PSBD)" evidence="12">
        <location>
            <begin position="111"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00019511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PRC92189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="413" mass="43201" checksum="2A91950C9961CD87" modified="2018-07-18" version="1">MAIVEVKVPQLSESVAEATLLQWHKEVGSSVARDENLIDIETDKVVLELPAPQAGVITQIVRPNGSTVVAGEVIAIIDTDATASAGAAPAPAATSAAAPVAATANVSKADVAMPAAAKILAENNMTATQVAGSGKDGRVTKGDALAAVSAPKAPVVAPLAAPAAKSALAQVAAPAAPNLGDRPEERVPMSRLRARIAERLIQSQSTNAILTTFNEVNMQPVLDLRNKYKDKFEKEHGVKLGFMSFFVKAAVAALKKYPIINASVDGNDIVYHGYFDIGIAVGSPRGLVVPILRNADQMSIADIEKKIGEFGNKAKEGKLTLDDLTGGTFSISNGGTFGSMLSTPIINPPQSAILGVHATKDRAVVENGQIVIRPMNYLAMSYDHRIVDGREAVLGLVAMKEALEDPARLLLDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GX12</accession>
    <name>A0A2S9GX12_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_2911</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92252">
        <property type="protein sequence ID" value="PRC92252"/>
        <property type="gene ID" value="S2091_2911"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015584428" evidence="3">
        <location>
            <begin position="25"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="222"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="126"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC92252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="257" mass="26502" checksum="7B46DD90EA53DDA3" modified="2018-07-18" version="1">MYKTTKLLALILSLSLLVAGNAYSSPTTSSKHSSTSHSTSFGSFGSSKKAQTTPAASTESTTSTSSTPSTPSADKSVGFGSFGSGSAATGTGKSTSVLSKNLDQNQAQQNALTTLDARNAQHAGVAGTTTGTTAPLANGTTLPPAQGYPTQPVQTVVYRDSPVSSSWYWFGMGSMFGHHSDTNVYVNGANQQNGQAGYPTNTNDPNGVAYQGQPPKKSGTSWLVVAIWLIIGAALIGLAWSYFTRAKAPAKPSNYSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GX73</accession>
    <name>A0A2S9GX73_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Peptidase family M28</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2978</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92319">
        <property type="protein sequence ID" value="PRC92319"/>
        <property type="gene ID" value="S2091_2978"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008235">
        <property type="term" value="F:metalloexopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045175">
        <property type="entry name" value="M28_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007484">
        <property type="entry name" value="Peptidase_M28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147">
        <property type="entry name" value="PTHR12147"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04389">
        <property type="entry name" value="Peptidase_M28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="335"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="365"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="407"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="437"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="462"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="491"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="520"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="546"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M28" evidence="2">
        <location>
            <begin position="113"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="766" mass="83367" checksum="373A53E2E834BEF6" modified="2018-07-18" version="1">MSTQLPVVQKINYVAGLIALIILIAVAAFGIQSERPPKPITAEAATKDFSSARAMSYLRHIAQEPHATGTDANAKVRQYLLTELKALGLTPQIQSGMGTYKSSRGGSIAMVHNILVRIPGQIPGKALLLAAHYDSVPGGAGAADDGASVAAILETIRALQSGAPLQNDLICLFTDGEEAGLLGSELFTAENPWVKDIGLALNFEYRGNGGPVLMFETSIGNGELITGFANSVTHPVSNSLLYEVYKLMPNDTDFTNFKAAGIPGMNFAAIENPSSYHTQLDRPELLNEGTLQHQGDMMLPLVRYFGNRPLIDLKSSDHVYFNVPGHGLIHYPVSWVFPLFALVIVLFMLVLIANMKKAEVRLGRMFIGALAFVLITMLLAGVCHLLWGAATWLHPSYQLLQNPYNSHWYLLAFVALVIGFFGAIQSGLARWLRPLELGLGAMLCWIVLLVASGFLMPGASFVLTWPLLAVLVAHLTLCSERIRNTSINTKMWILLVGTLPAVMLFAPLIRMLFIGLSPQMSAVIGLVVTLLLGIIAQLLALLTRRFLLPALPVVAGVAFLAAGSLTANFDIEHPRPSNVFYALDGVTNQALWLSDDVELSSWSKNFFPQKTSMRAVPEIFGEGSRSHQYWTSAAPDFGVPVPGIDVLQDVVTDNLRNVVVQIKSARHAPRLYVTIEGQEVLNSHVQGQDFSIISGSKWRLRTLGMPDDGINIALQFEPGKSFKIRVLDETYGLPQAGFPVRPPEIITKMSGSESDTILTVQVKQFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GX74</accession>
    <name>A0A2S9GX74_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Methionyl-tRNA formyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2925</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92266">
        <property type="protein sequence ID" value="PRC92266"/>
        <property type="gene ID" value="S2091_2925"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016742">
        <property type="term" value="F:hydroxymethyl-, formyl- and related transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005793">
        <property type="entry name" value="Formyl_trans_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002376">
        <property type="entry name" value="Formyl_transf_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036477">
        <property type="entry name" value="Formyl_transf_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011034">
        <property type="entry name" value="Formyl_transferase-like_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02911">
        <property type="entry name" value="Formyl_trans_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00551">
        <property type="entry name" value="Formyl_trans_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50486">
        <property type="entry name" value="SSF50486"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53328">
        <property type="entry name" value="SSF53328"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Formyl_trans_N" evidence="1">
        <location>
            <begin position="31"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="domain" description="Formyl_trans_C" evidence="2">
        <location>
            <begin position="207"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="303" mass="32909" checksum="CA7D7DDC74AA4593" modified="2018-07-18" version="1">MTDAIPTNSAVVFAYHSVGVHSIKVLLARGVNIALVVTHNDNPNETIWFDSVAALCAEHNIPTLFEPEPEPLFEAVAKLAPDFIFSFYYRNMLPVPLLALAKRGAYNLHGSLLPKYRGRVPVNWAVLHGATETGATLHEMAAKPDAGAIIAQTAVPILPDDTAHDVFGKLTVASEQTLWDAIPKLLAGTAPRIINDLSKGSYFAGRKPEDGRINWQQTAQQVYNLHRAVAPPYPGAFTDQNGHRFIIKQARLANSPKANLPQGLSVVDNVVFGLCGDGRALRINELLFNGSLITASQLQQLLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXQ2</accession>
    <name>A0A2S9GXQ2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2879</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92504">
        <property type="protein sequence ID" value="PRC92504"/>
        <property type="gene ID" value="S2091_2879"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="5"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="289" mass="32248" checksum="AB1FD3086AC6E50F" modified="2018-07-18" version="1">MRSNLPLNALRAFESSARHLNFTHAALELNVTQAAVSQQVRMLEERLGTILFKRLPRGLSMTDEGCALLPVLSDAFGRIEAVLKKFEGGHFREVLSVGVVGTFALGWLMPRLKLFQESHPIVELRLFTHNNKVDPAAEGLDFAIRFGEGTWPTTQNVALLEAPLAVLCAPEIARRIKVPGDLVNETLLRSYRNDEWNIWFAAAGLEPWMLSGPIIDSSRLMVEVAIQGDGVALAPPAMFTREIQSGLLVRTFDIEIKTGGYWLTWLKSRQMSVAMKLFHDWVIEQAEAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXQ9</accession>
    <name>A0A2S9GXQ9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fusaric acid resistance protein-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2874</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92499">
        <property type="protein sequence ID" value="PRC92499"/>
        <property type="gene ID" value="S2091_2874"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="57"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="82"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="132"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="193"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="241"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="267"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="292"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="323"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="470" mass="50875" checksum="7624610F7C1986A7" modified="2018-07-18" version="1">MKLMTSFKEASVTMLASILTLMCSLTLNPSTGSGVLAVVLCLSLSRSQLDRDQRGRIEAAFALPVVSMIAVGVGFLLLHTPWLGAFVFVAGMFLSIWLRRFGDMAQRAGSLIALPFVALLTTPHISHHQNSAVPAVLIPVVIALLALLWVSLLHTAAFHLRFLKPVPKVQTKSTASTKAKTESALKPIASTRMAIQMAVALGISFGIGYVYFPERWSWVVLTAFIVSAGNRGRLDVAYKSVLRVIGAAAGTLSAIAISTQIESHALNHQIVVALILGALFLGIWLRPMGYGWWALFVTLTLALLQELAGTSALRILWPRLEEICIGAVIAVATAWFVLPVRSTAVLRKRLSQALASLSDALDPAIPERKPDEFIAAVDAVEEIVPAFRASRLVMRYTHDQHPADWVDALLACKNPAVTLIECNATPGSARRAVGAARKSLREPKDILLSLQELRSSLIDSEKTIHVNEHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXY2</accession>
    <name>A0A2S9GXY2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">2-keto-3-deoxy-galactonokinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2623</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92568">
        <property type="protein sequence ID" value="PRC92568"/>
        <property type="gene ID" value="S2091_2623"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008671">
        <property type="term" value="F:2-dehydro-3-deoxygalactonokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034194">
        <property type="term" value="P:D-galactonate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.310">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007729">
        <property type="entry name" value="DGOK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042257">
        <property type="entry name" value="DGOK_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042258">
        <property type="entry name" value="DGOK_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05035">
        <property type="entry name" value="DGOK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="333" mass="35853" checksum="89D90A0DDCC0F236" modified="2018-07-18" version="1">MTYILTIDTGTTNTRVSLWHEATVIAHSATEVGVRDTAMSGNKTKLEEGVRKTILNTLAKANVTEEEVDLVIGSGMISSNVGLFELPHLPAPAGLQQLARGMVAVTIPSVFSKPIYLVPGVRNVVENIGLHNCEAMDMMRGEEVEVMGIIDQLGITGPAMLIMPGSHSKFVCIDEKNNIIGCVTTLAGELLYVITHNTILAKSLDSNFAEFINPEMLLAGAHSAQTIGLGRTCFNVRTLDQFTIYQRNDRANFLLGAILGADLLTLKNSTAIKMMPGTPIIICGKPIMKEALALLIQNDDYFSGKVTIVSNEMQEHLAGYGAIKVATARGLVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GY42</accession>
    <name>A0A2S9GY42_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">YqaJ-like viral recombinase domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2686</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92631">
        <property type="protein sequence ID" value="PRC92631"/>
        <property type="gene ID" value="S2091_2686"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.320.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011604">
        <property type="entry name" value="PDDEXK-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019080">
        <property type="entry name" value="YqaJ_viral_recombinase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09588">
        <property type="entry name" value="YqaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YqaJ" evidence="1">
        <location>
            <begin position="12"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="265" mass="29773" checksum="90F3E60569D4FF50" modified="2018-07-18" version="1">MKFLECIQGSEEWLQARSGLITASLFSEICIEVGGLDEKQKVYVDALLSGVGQKEAMIKAGYAAPPKSKTVARALEGEITTDYSDGAKRYASDLAIERISGHMYGIPPKAWVLNRGHEMEVHARRLYEGRTGAFVTEAGICVDENRFGYSTDGLVDNDGLIEIKSPIDSIKIEQMLITGDVSEYIHQMQGGMWLTNRKWCDFIMYVPDLESVEIELYVKRILRDDAFIDEMVVKLGRFSNLVAQKEAFFRSVKNTEAFNYLKEAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GY82</accession>
    <name>A0A2S9GY82_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2726</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92671">
        <property type="protein sequence ID" value="PRC92671"/>
        <property type="gene ID" value="S2091_2726"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="170" mass="18500" checksum="9CA0EAC90EE4AE08" modified="2018-07-18" version="1">MTIIVEDGTGVTGAESYVTVAFCTAYHAARNNTAWAAIANDTLREGYLRLATDYMVQAYRGKWKGLRAGITQALDWPRRSVVLDDLALYYAVPYTIVPTEVMNACCILALKASAGDLAPDLDRATASEIVGPITTTYFAGSPQHTRYRSVDLLLKPYIDGTDTNGQLVRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYG9</accession>
    <name>A0A2S9GYG9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">2OG-Fe(II) oxygenase superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2436</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92706">
        <property type="protein sequence ID" value="PRC92706"/>
        <property type="gene ID" value="S2091_2436"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044862">
        <property type="entry name" value="Pro_4_hyd_alph_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13640">
        <property type="entry name" value="2OG-FeII_Oxy_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2OG-FeII_Oxy_3" evidence="1">
        <location>
            <begin position="120"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="272" mass="31561" checksum="5B29DC25D66D7542" modified="2018-07-18" version="1">MFRDELVDLIVTRLQEDKTTAREFFMQSKKDVGVRYCYIENLLPEDIAKKIYSVFPSLGQMRLMSSFRERKYTSKHFDQFNSILKDITFAMQDVAVVKVIEEITGITQQIPDPTLYAGGLSMMGEGHFLNPHIDNSHEVSRRYYRTLNLLYYVTPDWEIQNGGNLELWEKSVRENVVIHSKFNRLVLMETTPTSWHSVSPIIVPKLRCCVSNYYFSPVSPIKQDYFNVTSFSARPEQTFRRTAAWIDNGLRQAVRAIFPDGVGAKDLYKGDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYK2</accession>
    <name>A0A2S9GYK2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2535</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92805">
        <property type="protein sequence ID" value="PRC92805"/>
        <property type="gene ID" value="S2091_2535"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="3"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="306" mass="33514" checksum="2AE47F54DE457711" modified="2018-07-18" version="1">MSDRLNGISAFVEAAEAGSFALAAERMRLTRSSVGKSIARLEQRLGVRLFQRTTRSQSLTEEGQAYYERCVRALAELSAGALALDSGKGEPIGRLRVSVPVLFGRHCAAPVLRALAHQFPRLDIEISFNDQTVDLVDEGYDLAIRIGSLPDSSTLVARRLSSQRMVICAAPSYLAKYGKPGSADELSQHVGIAYGRSGRVKPWLMRDSAGQIQKPQIDIRLMFDDLQAITDAAIAGAGLAWLPCWLMAKHSRAGELELVMNDNMLEVEIYAVWPKSHYLPTKTRVAIDALVAEIPGMIGHLEHVCE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYK3</accession>
    <name>A0A2S9GYK3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NHLM bacteriocin system secretion protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_2529</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92799">
        <property type="protein sequence ID" value="PRC92799"/>
        <property type="gene ID" value="S2091_2529"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039562">
        <property type="entry name" value="MFP_biotin_lipoyl_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022275">
        <property type="entry name" value="NHPM_bacteriocin_SS_HylD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13533">
        <property type="entry name" value="Biotin_lipoyl_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="SSF51230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03794">
        <property type="entry name" value="NHLM_micro_HlyD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="33"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="domain" description="Biotin_lipoyl_2" evidence="3">
        <location>
            <begin position="76"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="193"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC92799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="422" mass="46426" checksum="22CCA9EA344D4040" modified="2018-07-18" version="1">MIKKELFREVAVNRLSSPEQLDSLLQVTTVKGWAALAGIILFLVTIGGWSVFGKLPTKLVGDQCILVNSGGVNILTTSVSGRLSDLAVEAGDVVTRGQIIGRLEQYDMLQKINANEAHLSEAALQYKQTLMLAQQGAKLREVTMAAQSNNLNDQLAANSQKMKLLNERIETQKSLYDQGLITKKTLIDSQLELTSTELEAETIRTQIKQLEVTRLDNKKQSDNEILQVKNQLEELQRNVAAMVRENKGSTSIVSPYAGKVVEVKAVEGQLVERGTPLLSVESDGADTNELEAYIYLPASDGKKINRGMKVEISPSTARREEFGFLPANISSVANFPSSDLGLMRVFGNEKIVQQLSGTHAPIQIRVSLKPSGSNFSHYEWSTRRGPQFLIQSGTMCSANITLSEQRPIEILIPILKKTIGFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYQ7</accession>
    <name>A0A2S9GYQ7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2579</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92849">
        <property type="protein sequence ID" value="PRC92849"/>
        <property type="gene ID" value="S2091_2579"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="43" mass="4920" checksum="00899952A4DB2803" modified="2018-07-18" version="1">MLFVFEKMAYYIGHFLVEIFGGTLKADEIFALAGMTDLRFLIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYT3</accession>
    <name>A0A2S9GYT3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Segregation and condensation protein B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_2290</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92873">
        <property type="protein sequence ID" value="PRC92873"/>
        <property type="gene ID" value="S2091_2290"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051304">
        <property type="term" value="P:chromosome separation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005234">
        <property type="entry name" value="ScpB_csome_segregation"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34298">
        <property type="entry name" value="PTHR34298"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04079">
        <property type="entry name" value="SMC_ScpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00281">
        <property type="entry name" value="TIGR00281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1" id="KW-0132">Cell division</keyword>
    <keyword evidence="2" id="KW-0159">Chromosome partition</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="240"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="242"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC92873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="279" mass="31021" checksum="D0835581881B77C4" modified="2018-07-18" version="1">MNTAEAKVVLETALLCAHEPLTLHSMKKLFVDESSIDDVIGNDALKLMLGMLRNEWQERGIELVSLATGWRFQSRPVMRKYLDRMNPEKPPKYSRAALETLAIIIYKQPVTRGDIEEIRGVTVNAQTIRMLEDRGWIETIGHRDVPGRPALFASTKQFLDDLGLASLEQLPPLQAVSQEMMKVTDLEQMEVIETHLQANLPESLLQSNMDFSAADEVGNDNQAAVALVEQAPDVKDVMSIETEANSAETSESSSEITLILNDPVPELMVEDAPGLPNQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYZ5</accession>
    <name>A0A2S9GYZ5_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Nucleoid-associated protein S2091_2376</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_2376</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Nucleoid</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the YbaB/EbfC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92959">
        <property type="protein sequence ID" value="PRC92959"/>
        <property type="gene ID" value="S2091_2376"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043590">
        <property type="term" value="C:bacterial nucleoid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1310.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00274">
        <property type="entry name" value="DNA_YbaB_EbfC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036894">
        <property type="entry name" value="YbaB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004401">
        <property type="entry name" value="YbaB/EbfC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33449">
        <property type="entry name" value="PTHR33449"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02575">
        <property type="entry name" value="YbaB_DNA_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004555">
        <property type="entry name" value="UCP004555"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82607">
        <property type="entry name" value="SSF82607"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00103">
        <property type="entry name" value="DNA_YbaB_EbfC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="85"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="6"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC92959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="108" mass="11546" checksum="C5545ECDB34E5BF0" modified="2018-07-18" version="1">MMKGQLAGLMKQAQAMQDNMKKAQDQLALVEVEGQSGAGLVKVVMTCKNDVKRITIDPSLLSDDKDMLEDLVAAAVNDAIRKAEATSQEKMSGLTAGLPLPPGFKLPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZ79</accession>
    <name>A0A2S9GZ79_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Plasmid stabilization system protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2120</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93034">
        <property type="protein sequence ID" value="PRC93034"/>
        <property type="gene ID" value="S2091_2120"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2310.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007712">
        <property type="entry name" value="RelE/ParE_toxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035093">
        <property type="entry name" value="RelE/ParE_toxin_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05016">
        <property type="entry name" value="ParE_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-1277">Toxin-antitoxin system</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="96" mass="10860" checksum="E982D303C11F8416" modified="2018-07-18" version="1">MQSSVVWLSEAIAEKDDILNYIAERNVLAALGIDTHIKQQVSQLIEFTLLGRKGRISGSFELVISSTPYLVAYQVQGDQVQILHVFHERRNCPPEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZE2</accession>
    <name>A0A2S9GZE2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2159</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93073">
        <property type="protein sequence ID" value="PRC93073"/>
        <property type="gene ID" value="S2091_2159"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="89" mass="10525" checksum="300C672809E50E69" modified="2018-07-18" version="1">MADLHLHLKGEYFDQIKAGTKTHEFRSCHKWEKRLGGKSFDRIFIKRGYPKTGDVSRIIQRPWMGYERINITHPHFGLEAIEVFAIRVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZE3</accession>
    <name>A0A2S9GZE3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Peroxiredoxin, Ohr subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2403</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the OsmC/Ohr family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92986">
        <property type="protein sequence ID" value="PRC92986"/>
        <property type="gene ID" value="S2091_2403"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019953">
        <property type="entry name" value="OHR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003718">
        <property type="entry name" value="OsmC/Ohr_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036102">
        <property type="entry name" value="OsmC/Ohrsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33797">
        <property type="entry name" value="PTHR33797"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02566">
        <property type="entry name" value="OsmC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82784">
        <property type="entry name" value="SSF82784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03561">
        <property type="entry name" value="organ_hyd_perox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="142" mass="14480" checksum="0B6341E9069346A0" modified="2018-07-18" version="1">MATKLEKVLYTAHAHTTGGRDGRSVTDDGLLDVKLSPPKAMGGAGNATNPEQLFAAGYSACFMGAIKHVAGVKKVAVPADASIDASIDIGPIPAGFGIAAKLVISLPGLDRTVAQDLVDSAHQVCPYSNATRGNIVVELVLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZM8</accession>
    <name>A0A2S9GZM8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2270</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93184">
        <property type="protein sequence ID" value="PRC93184"/>
        <property type="gene ID" value="S2091_2270"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016980">
        <property type="entry name" value="S-AdoMet-dep_MeTrfase_Alr7345"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF031679">
        <property type="entry name" value="Mtase_Alr7345_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5016276938" evidence="1">
        <location>
            <begin position="32"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="271" mass="29293" checksum="DB719F21F8842539" modified="2018-07-18" version="1">MKLLFNLSKHNLLFVLCFVITLLMSINQARATDVVKDGAINTEVSRPAEDKARDTDRKPAEMLEFAQVKPGQLVIDYIPGKGYFTRIFSAAVGTQGAVYAVMPQFLIDKFKGRSLPPSVSVEPGHTNVHDAISNGVQMNVPVKVDLVWTSQNYHDVHIAGGADATAQLNKAVFDALKPGGLYVVLDHAGAAGLDDASIAKLHRIDRALVVKEVTAAGFILDGESMALRNPADSHSVAVFDPSIRGKTDQFILRFRKPLDMASHTTAPMTGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZV0</accession>
    <name>A0A2S9GZV0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93262">
        <property type="protein sequence ID" value="PRC93262"/>
        <property type="gene ID" value="S2091_2000"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="56"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="87"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="114"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="141" mass="15610" checksum="5F4CA258061D2EC8" modified="2018-07-18" version="1">MLAQLLVLISAGIILLLGLAHLAITYLGNKLHPRDAELTERLKTTSPVISRRTSIWNAWIGFNASHSLGAILFGVMFGYLAAQQPMLLFHSYFLGLTGLVTLCAYLTMAKLYWFKLPFQGISLALLFYVAGFIAENSRVFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZY0</accession>
    <name>A0A2S9GZY0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative hydrolase of the alpha/beta superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2030</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93292">
        <property type="protein sequence ID" value="PRC93292"/>
        <property type="gene ID" value="S2091_2030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="206" mass="22545" checksum="E6E8F0BC45C3DF87" modified="2018-07-18" version="1">MNAQTRSFFLTGGAGQMQCALDLPLDQAPIGIALVAHPHPLYGGTMDNKVAQTLARTFVALGYATARMNFRGVEQSEGVHDHGIGETEDMQILLAHMQTLYPDLPLALSGFSFGTFVQSRLQRLLAAQNSPPQRLVLIGCAAGKWEMGEVPASTILIHGEQDTTIPLTDVFDWARPQDIPVTVIPGADHFFHRKLHHIKNLVTALW</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H018</accession>
    <name>A0A2S9H018_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2059</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93321">
        <property type="protein sequence ID" value="PRC93321"/>
        <property type="gene ID" value="S2091_2059"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021728">
        <property type="entry name" value="DUF3300"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40269">
        <property type="entry name" value="PTHR40269"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11737">
        <property type="entry name" value="DUF3300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015628002" evidence="2">
        <location>
            <begin position="29"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="251"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="274" mass="30671" checksum="362713DD3460E8D4" modified="2018-07-18" version="1">MMSIFSSRRFAVFSLLVIGFLSSTFALAQAIPSNNTAAYSPQQLETLVGRIALYPDDLIAITLPASTYPLDVVKAQRFLDKFRMDNSLMPDPSMADPVVKLLNYPDIIRLMNDDLDWTQALGDAVDADETGALAAIQSFRRQAESVGNLKSDAKQVVAVDNKIITIVPINPEVIYVPMYQPARVIVYSPTPYVWSYYPTPYPSYYYPYPIGGRFSFGFTWGAAVGSGWYTNWRDGHINNHVATNIHDYANRPSGGQNWRNNRPPTQTKIGIQTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H047</accession>
    <name>A0A2S9H047_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8 9">Uroporphyrinogen decarboxylase</fullName>
            <shortName evidence="8">UPD</shortName>
            <shortName evidence="8">URO-D</shortName>
            <ecNumber evidence="4 8 9">4.1.1.37</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">hemE</name>
        <name evidence="12" type="ORF">S2091_2093</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 9">
            <text>4 H(+) + uroporphyrinogen III = 4 CO2 + coproporphyrinogen III</text>
            <dbReference type="Rhea" id="RHEA:19865"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57308"/>
            <dbReference type="ChEBI" id="CHEBI:57309"/>
            <dbReference type="EC" id="4.1.1.37"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 8 9">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; coproporphyrinogen-III from 5-aminolevulinate: step 4/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 8">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8 10">Belongs to the uroporphyrinogen decarboxylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.37" evidence="4 8 9"/>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93355">
        <property type="protein sequence ID" value="PRC93355"/>
        <property type="gene ID" value="S2091_2093"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00251">
        <property type="reaction ID" value="UER00321"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004853">
        <property type="term" value="F:uroporphyrinogen decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006782">
        <property type="term" value="P:protoporphyrinogen IX biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00717">
        <property type="entry name" value="URO-D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.210">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00218">
        <property type="entry name" value="URO_D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038071">
        <property type="entry name" value="UROD/MetE-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006361">
        <property type="entry name" value="Uroporphyrinogen_deCO2ase_HemE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000257">
        <property type="entry name" value="Uroporphyrinogen_deCOase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01208">
        <property type="entry name" value="URO-D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51726">
        <property type="entry name" value="SSF51726"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01464">
        <property type="entry name" value="hemE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00906">
        <property type="entry name" value="UROD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 8 9" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="6 8 9" id="KW-0456">Lyase</keyword>
    <keyword evidence="7 8 9" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uroporphyrinogen_deCOase" evidence="11">
        <location>
            <begin position="26"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="8">
        <location>
            <begin position="31"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="81"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="157"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="212"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="333"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="8">
        <location>
            <position position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS00906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PRC93355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="362" mass="40035" checksum="E6AE9A5E2BA9D8B6" modified="2018-07-18" version="1">MSFIDTPLQNDTFLRALQRQPTEHTPVWLMRQAGRYLPEYRAVRQKAGSFMSLAKNPDFATEVTIQPLDRFKLDAAILFSDILTVPDAMGLGLYFEDGEGPKFERPLRDETDILALQVPDMSNLQYVFDAVTQIRNTLQGRVPLIGFSGSPWTLACYMVKGGGSKDFRTVKSMLYNRPDLMHHILRVNAAAVATYLNAQIDAGAQAVMIFDSWGGALADGAYQTFSLDYMREVLRLVKTEKNGVKIPSIVFTKGGGLWIDQIADIGADAVGLDWTVNLGKARAQIGHKVALQGNLDPMALFAKPEQIRQQVQELIQSYGKPTDGNGHVFNLGHGISQFTAPESVEVLVDAVHEFSKAIRSNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0C8</accession>
    <name>A0A2S9H0C8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2054</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93316">
        <property type="protein sequence ID" value="PRC93316"/>
        <property type="gene ID" value="S2091_2054"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025500">
        <property type="entry name" value="DUF4390"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14334">
        <property type="entry name" value="DUF4390"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015416944" evidence="1">
        <location>
            <begin position="26"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="189" mass="22044" checksum="072FF3BDE62EC493" modified="2018-07-18" version="1">MQRLIHLLLFSMLSCLLFGQPSAHASSIEISYARIESSDDSYRLAASFNFELTHELENVITSGIPLYFVTEVEITRPRWYWFDEKTITNEQTVRISYNVVTRQYRASVNGNFAQNYKDLDEALSLVRHPSRWMVAEKTSLSRGATYNIAVRSRLDTNQLPKPFQFNALNNSDWRLSSDWKRMTFKADEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0E8</accession>
    <name>A0A2S9H0E8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1820</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93433">
        <property type="protein sequence ID" value="PRC93433"/>
        <property type="gene ID" value="S2091_1820"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="99" mass="11169" checksum="3220F7C850574AFE" modified="2018-07-18" version="1">MTSTDQIHAQQSPPLITHLAVDTIDAYTQARDIVSDLSAIFEVLDHLALTDFCNDRITPILFRAGFCHATERLKFIDERITDAYKTLDDLKTDSSLNTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0G3</accession>
    <name>A0A2S9H0G3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="8">MacB-like periplasmic core domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_1856</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93469">
        <property type="protein sequence ID" value="PRC93469"/>
        <property type="gene ID" value="S2091_1856"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025857">
        <property type="entry name" value="MacB_PCD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12704">
        <property type="entry name" value="MacB_PCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="258"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="301"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="343"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="domain" description="MacB_PCD" evidence="7">
        <location>
            <begin position="25"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF12704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC93469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="380" mass="41511" checksum="039A219689895583" modified="2018-07-18" version="1">MKYSGILRIGFKLLVNDKAKFSALLIGITFAVFLMVQMTSMFAGILNRAYSTVTNIGANIWIIDPAVNIPTSSIPLPDYLLDAVRSMDGVSYAVPLFIGGAQLKLNDGTNQSVSVIGLDDNSLFGRPELEQGNILDIYADNSFIVVDDTEFPKLENPKIGTTFELNDYRGVISGIAKVNANGLNGVPTLYTTYHRAIQYIPTTRFTISYVLVQAKNDAAIASIKKNVAKLGYVALTKDEFNQRIADFYIFQTGIGTNILLMTVISFIVGLSISGQTFYTFILENIDKFGALKAIGAKGRELVYMILFMATFTSLTGYGLGIGLVTMVISIARANVPNYAAMITFWNLGLAFGMVVLIAGISSYFGVRKVLKIEPFDIFRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0P0</accession>
    <name>A0A2S9H0P0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Exosortase A system-associated amidotransferase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_1924</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the asparagine synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93537">
        <property type="protein sequence ID" value="PRC93537"/>
        <property type="gene ID" value="S2091_1924"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004066">
        <property type="term" value="F:asparagine synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006529">
        <property type="term" value="P:asparagine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01991">
        <property type="entry name" value="Asn_Synthase_B_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00712">
        <property type="entry name" value="AsnB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006426">
        <property type="entry name" value="Asn_synth_AEB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001962">
        <property type="entry name" value="Asn_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033738">
        <property type="entry name" value="AsnB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017539">
        <property type="entry name" value="Exosortase-1_amidotfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00733">
        <property type="entry name" value="Asn_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13537">
        <property type="entry name" value="GATase_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001589">
        <property type="entry name" value="Asn_synthetase_glu-h"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01536">
        <property type="entry name" value="asn_synth_AEB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03108">
        <property type="entry name" value="eps_aminotran_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0061">Asparagine biosynthesis</keyword>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 5" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="8">
        <location>
            <begin position="2"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="active site" description="For GATase activity" evidence="5">
        <location>
            <position position="2"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="100"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="291"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="363"/>
            <end position="364"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="site" description="Important for beta-aspartyl-AMP intermediate formation" evidence="7">
        <location>
            <position position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR001589-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR001589-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR001589-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC93537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="631" mass="71822" checksum="BDDE9D33281D48BB" modified="2018-07-18" version="1">MCGIVGIFDTQGTREINRQTLNKMNESQHHRGPDEGELHLETALGMGHRRLSVIDLESGQQPLFNEDRSVVIVYNGEIYNYRELMSELIQLGHKFHTRSDTEVVVHAWEEWGESCVHHFRGMFAFGIWDRNQQTLFLARDHVGVKPMFYSLLPDGFFVFGSELKSIMTFPALSRKLNPQAVEDYFAYGYIPEPKTIFNNAYKLSPGHHITIKVGDNSVQQVKYWDLPFKTEPPRSEQEIAHELIDRLRDSVQSQMVAEVPLGAFLSGGVDSSAVVAMMAQKNKEAVNTCSIAFNDPAYDESQFANQVAQRYETTHHTNTVSMDDYGLIDTLAHLYDEPYSDSSAIPTYRVCQLARKRVTVALSGDGGDENFAGYRRYRYAMAEQSVRSILPSGLRKPLFGTLGKLYPKADWAPRMFRAKTTFEALANDLVEGYFHGVSIMPDRVRDQLFNDQFRTELQGYRAIQVMQEHAALAPTEDPLSLIQYLDFKTYLPGDILTKVDRASMAHSLEVRVPLLDHTFVEWVSGLPPTMKLRGAEGKYIFKKSLQPYLSDEILYRAKKGFSIPLADWIRGPLRSKVRAAVLNPMMLDTGIFNEPYLHHMLEQHESGLKDYSAPLWSLLMFATFLRVSVNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0P3</accession>
    <name>A0A2S9H0P3_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">dTDP-glucose 4,6-dehydratase</fullName>
            <ecNumber evidence="4 5">4.2.1.46</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_1556</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>dTDP-alpha-D-glucose = dTDP-4-dehydro-6-deoxy-alpha-D-glucose + H2O</text>
            <dbReference type="Rhea" id="RHEA:17221"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:57477"/>
            <dbReference type="ChEBI" id="CHEBI:57649"/>
            <dbReference type="EC" id="4.2.1.46"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 5">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 5">Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.46" evidence="4 5"/>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93555">
        <property type="protein sequence ID" value="PRC93555"/>
        <property type="gene ID" value="S2091_1556"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008460">
        <property type="term" value="F:dTDP-glucose 4,6-dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009225">
        <property type="term" value="P:nucleotide-sugar metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05246">
        <property type="entry name" value="dTDP_GD_SDR_e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005888">
        <property type="entry name" value="dTDP_Gluc_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16363">
        <property type="entry name" value="GDP_Man_Dehyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01181">
        <property type="entry name" value="dTDP_gluc_dehyt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-bd_dom" evidence="6">
        <location>
            <begin position="3"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001539"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF16363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC93555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="355" mass="39991" checksum="6482E35B0DC54C80" modified="2018-07-18" version="1">MILVTGGAGFIGSNFVLDWLSQSDETVINLDALTYAGNRENLSSLIGDNRHIFVQGDIGDSVLVAALLAKHQPRAIINFAAESHVDRSILGPEDFIQTNIVGTFHLLEAVRGYWANLQGDAKQQFRFLHVSTDEVYGSLTKDEPAFTETHRYEPNSPYSASKAASDHLVRSYHHTFGLPVLTTNCSNNYGPYHFPEKLIPLMIVNALAGKPLPIYGDGQQIRDWLYVKDHCSAICRVLEAGVVGEVYNVGGWNEKPNIEIVHTLCDLLDELRPRDEGKSYREQIITVVDRPGHDRRYAIDASKIERELGWKPSETFETGIRKTVDWYLVNQPWVANVQSGEYRAWVEKNYNERCA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0U3</accession>
    <name>A0A2S9H0U3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93599">
        <property type="protein sequence ID" value="PRC93599"/>
        <property type="gene ID" value="S2091_1600"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002656">
        <property type="entry name" value="Acyl_transf_3_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01757">
        <property type="entry name" value="Acyl_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="63"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="107"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="148"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="187"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="231"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="263"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="285"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="325"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="356"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl_transf_3" evidence="2">
        <location>
            <begin position="27"/>
            <end position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="390" mass="43738" checksum="55BA57ED4303059F" modified="2018-07-18" version="1">MFPKIPKYNDVGDQLLPTKSAPISRNARVDFLRGVAISCVLILHFALAFGFKNSPLGTLLSPALLHAIAFNGNFGVTMFFVISGFLITSNSLSRWNNLKEINARTFYLFRFARIMPSLLLVLAIIVTLGCLDIPFFDNSDNNHHLPSSYFLISIGSVLSFWHNVLMQTSGYINYCIDVYWSLSVEEVFYLALPLVCLLLRRTWLIVAVCITAIVIGPIYRSQHTNNEIFFMYGYFACFDAIAFGCITALLARRGIIPIKFNRVLRLAAAIALGVVYLRGIDGHEIFGFSLIALASAAFLLGAANDNSPGWSTGRLSSGVRWVGRYSYEIYLFHIVVLGLMRNVLTKEQLSYSARLPWFLLFLVLTALVAWLVARYVSEPANTAIRRRYGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H171</accession>
    <name>A0A2S9H171_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1736</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93735">
        <property type="protein sequence ID" value="PRC93735"/>
        <property type="gene ID" value="S2091_1736"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="24"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="50"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="118" mass="12685" checksum="0CC1310C1C65D6E3" modified="2018-07-18" version="1">MVSPLFFSKKISALTMSRRDKLPLFSYSIMGMLIMAMLLSFTMVSRHATAQTPASPPASAPAGAGAGAKFADHKTKELARIAHHLEVLQTLQSCVQAANDHAAMKTCNETAKASEHQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H179</accession>
    <name>A0A2S9H179_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_1743</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93742">
        <property type="protein sequence ID" value="PRC93742"/>
        <property type="gene ID" value="S2091_1743"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002549">
        <property type="entry name" value="AI-2E-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01594">
        <property type="entry name" value="AI-2E_transport"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="29"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="61"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="147"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="203"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="246"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="294"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC93742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="340" mass="36864" checksum="0F1413529342CEE1" modified="2018-07-18" version="1">MNNKLTLPLVSSYLLAVLAGIVVLKAGLLLALFSGLLVYSLVHLLTPLVGKKIKFVKARIFVLAILSVIVISGLTALIFSAVTFAKSDAGSLHMLLQNLAGIIEVSRSQVPTWLSDYLPTGSDALREVMSDWLREHGQEAKLWGQEAGHSIIHLLMGMIIGGMIAINDARSKLPEFAGALLQRSVNLHTAFQRIVFAQVRISAINAAFSAIYLLVILPACGVHLPFSKTMVLITFVTGLLPVVGNIISNTVVVIVSLSHSLEIAMFSLLYMVLIHKFEYFLNAKIIGTQINAKAWELLIAILVMESLFGIPGLIAAPVFYAWLKIELGMGCTPAAPVQHY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H199</accession>
    <name>A0A2S9H199_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1374</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93765">
        <property type="protein sequence ID" value="PRC93765"/>
        <property type="gene ID" value="S2091_1374"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="SSF52151"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="366" mass="40596" checksum="8306F749732EE464" modified="2018-07-18" version="1">MKPGLKSSIILRAGPLALDHIRQHGLQASDIAVIPAAAGGPKGLILQALDQWVFGEWLANAPRERSLIGASIGAWRMAAASMKNPAQGFARLGELYCNQLYPAKPSSTYVTEVIQELLSQFISGHEHDIVQQTTHRLHVLTTKGRGWLRAPAHSFSTKAGFVAASLANIGSRSQLANHMERVVFSDQRDQLPWLKTKFDAFATEFTALNTENLKAALLASGTLPLIMDPVRNIPKAPHGTYWDGGLIDYHLALPYSRLSTGNLVLYPHFTDHIVPGWLDKAFAWRRANKGKNQHWLDNVVLVAPSAEFISALPRQKLPDRKDFAYHGTNHQQRIQEWQQAIAASAQLRDAFAAFIEKPDMNLIQPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1F2</accession>
    <name>A0A2S9H1F2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1423</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93814">
        <property type="protein sequence ID" value="PRC93814"/>
        <property type="gene ID" value="S2091_1423"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025337">
        <property type="entry name" value="Questin_oxidase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35870">
        <property type="entry name" value="PTHR35870"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14027">
        <property type="entry name" value="Questin_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="345" mass="38170" checksum="32C7494EE0921118" modified="2018-07-18" version="1">MHIKLSTLGEMLESQSSFLLDPEGFSNHGPMVLIALAKMGASEQQLRTYLTNSNQENRFHSELAQAKKLSITQQTWPQQLNQTDNFSQLQIFFKNWITQTSADQVLIEVLNQIPAAPASVAFHAIIRLAYGLEVNHSGEIAAGLAALVVGNLPISIEFRNKEPAANVLDGLAALSTEMKGFDTQEINITDRIRAVVADPRFARTVPAMPLHDDLLDEMAKTAIVIYSQTHNFTALHMVTGLHAARLVFSRLPISLIKQFMPSLWLAYCAAYASIGAPQIAPKILTAEPTAAPSKHLNNQPWEALFAQTLNSQRDHMIKMIYTCHQEYLRDPSPLYLDSANAILAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1K4</accession>
    <name>A0A2S9H1K4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Invasion protein B family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1468</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93859">
        <property type="protein sequence ID" value="PRC93859"/>
        <property type="gene ID" value="S2091_1468"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003065">
        <property type="entry name" value="Invas_SpaK"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03519">
        <property type="entry name" value="Invas_SpaK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01305">
        <property type="entry name" value="SSPAKPROTEIN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="135" mass="15329" checksum="C4CA81D5F722F878" modified="2018-07-18" version="1">MHQHDLGELVKRALVRSGCEPSLIRQLDHHATIQIDLIDAPALYVGRMGEQVVIWSDLCEFYDGILRRNSDALLHELMSGFPYSRNQQLVLRESDGQLQVYADVASECLDDVAAMSEALNAFFESQTRLLEIIRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1R6</accession>
    <name>A0A2S9H1R6_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 2">Protein ApaG</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">apaG</name>
        <name evidence="4" type="ORF">S2091_1108</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC93935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93935">
        <property type="protein sequence ID" value="PRC93935"/>
        <property type="gene ID" value="S2091_1108"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1470">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00791">
        <property type="entry name" value="ApaG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007474">
        <property type="entry name" value="ApaG_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036767">
        <property type="entry name" value="ApaG_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023065">
        <property type="entry name" value="Uncharacterised_ApaG"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04379">
        <property type="entry name" value="DUF525"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110069">
        <property type="entry name" value="SSF110069"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51087">
        <property type="entry name" value="APAG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ApaG" evidence="3">
        <location>
            <begin position="1"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00017693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC93935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="124" mass="13727" checksum="F327805F74CE7122" modified="2018-07-18" version="1">MALYEFSVSVATKYLGQQSDPEASRYVFSYTITIKNTGTAKAQLIARHWIIKDANDHEEQVRGLGVVGYQPLLEPGQQFEYTSGTALATPIGSMHGTYLCVAEDGEQFNATIPEFVLSLPWTLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1W7</accession>
    <name>A0A2S9H1W7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glycosyl transferase family 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_1131</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC93958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93958">
        <property type="protein sequence ID" value="PRC93958"/>
        <property type="gene ID" value="S2091_1131"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="254"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="285"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_trans_2-like" evidence="3">
        <location>
            <begin position="10"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC93958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="328" mass="36401" checksum="B6BC75C981A6FFFC" modified="2018-07-18" version="1">MNNPILPLISVVIPCYRVTQHILAVIDGIGSEVSQIYVIDDKCPDHSGNFVRANCRDQRVVVIDHLENQGVGGAVMSGYVAALAGGADIIIKLDGDGQMDARLIPNFIAPILSGEADYTKGNRFFDLEQIRAMPTVRLFGNAVLSFITKVSSGYWDIFDPTNGYTAIHAEALRHLPFKKISHRYFFESDMLFRLNTLHAVVVDIPMDANYGDEVSNLKISKIVTEFLGKHIRNFFKRLFYNYYLRNMSLASIELPLGVGLVLMGGSYGVWHWLNSARIDTATPAGTVMLAALPILMGIQLILAFLAYDIASVPHRPIHKKILLKKPNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H203</accession>
    <name>A0A2S9H203_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1153</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC93980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93980">
        <property type="protein sequence ID" value="PRC93980"/>
        <property type="gene ID" value="S2091_1153"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="126" mass="14655" checksum="595E0407B2E1A3C1" modified="2018-07-18" version="1">MMLVKVDGKDAKSVVVALIKNVRKLPIELYKQLTWNRSSEMTGHKRFTLLTDIQVYFCDSQSPWHHGSNENTNELLSLYFPKGLDLSTFSQVKLNAVARRLNERPRKTLNYKTLAEIFYQYVASTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H209</accession>
    <name>A0A2S9H209_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Sec-independent protein translocase protein TatB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">tatB</name>
        <name evidence="10" type="ORF">S2091_1170</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell membrane</location>
            <topology evidence="9">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the TatB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC93997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93997">
        <property type="protein sequence ID" value="PRC93997"/>
        <property type="gene ID" value="S2091_1170"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033281">
        <property type="term" value="C:TAT protein transport complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008320">
        <property type="term" value="F:protein transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043953">
        <property type="term" value="P:protein transport by the Tat complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00237">
        <property type="entry name" value="TatB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003369">
        <property type="entry name" value="TatA/B/E"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018448">
        <property type="entry name" value="TatB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02416">
        <property type="entry name" value="TatA_B_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01410">
        <property type="entry name" value="tatB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="2 9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0811">Translocation</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1 9" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC93997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="166" mass="18330" checksum="E297713B44C9576E" modified="2018-07-18" version="1">MIDLGLAKLALIGAVALVVIGPEKLPKVARMAGSLLGRAQRYLNDVKAEVSREIELDELRKMQADVETAASEFKSSVAKEMTDVEHGVNSIWDGDQVSAKQSLQAIPEEANIARKAREFRRKKLLRNSALPAWYKQQQGSKTRILSASARVAKYRPGSKSTQSFYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H214</accession>
    <name>A0A2S9H214_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Flagellar P-ring protein</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Basal body P-ring protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">flgI</name>
        <name evidence="5" type="ORF">S2091_1515</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 4">Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 4">Bacterial flagellum basal body</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the FlgI family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93906">
        <property type="protein sequence ID" value="PRC93906"/>
        <property type="gene ID" value="S2091_1515"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009428">
        <property type="term" value="C:bacterial-type flagellum basal body, distal rod, P ring"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030288">
        <property type="term" value="C:outer membrane-bounded periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071973">
        <property type="term" value="P:bacterial-type flagellum-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00416">
        <property type="entry name" value="FlgI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001782">
        <property type="entry name" value="Flag_FlgI"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30381">
        <property type="entry name" value="PTHR30381"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02119">
        <property type="entry name" value="FlgI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01010">
        <property type="entry name" value="FLGPRINGFLGI"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0975">Bacterial flagellum</keyword>
    <keyword evidence="5" id="KW-0966">Cell projection</keyword>
    <keyword evidence="5" id="KW-0969">Cilium</keyword>
    <keyword evidence="5" id="KW-0282">Flagellum</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015794586" description="Flagellar P-ring protein" evidence="4">
        <location>
            <begin position="27"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC93906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="376" mass="39778" checksum="C7E9AE3C3878AFFC" modified="2018-07-18" version="1" precursor="true">MRRLLNFKQLIIALLCCSVFITNAMAESESVRLKDLGKFAGWRENALVGYGLVTGLAGTGDSSSNKATRQSIANMLAQFDVAVSPDDIVSRNTAAVMVTAVLPPYTTTGDTLDVTVTSMGDARSLSGGSLLITPLKAPNNKVYALAQGPVSLGGYKFAQNGTLAQKNHPTVGSIPNGASVEVAVKANVLSPEGKLTFTLADADYTTAARVAFAVNNAFGASIADPRDAESIEIRVPDNLHLVAFMARIESLNVEPDVRARVVVNERTGTIVAGGDVRISKVVISHGDLKISIVTDNTVSQPIYVRQTGRGVRTQSISNSRIDVDEREESGYVSASNNTVADLIQALTQIKTNTRDIISILRAIKAAGALHADLVVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H233</accession>
    <name>A0A2S9H233_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="8 10">1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase</fullName>
            <ecNumber evidence="8 10">5.3.1.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">hisA</name>
        <name evidence="11" type="ORF">S2091_1176</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8 10">
            <text>1-(5-phospho-beta-D-ribosyl)-5-[(5-phospho-beta-D-ribosylamino)methylideneamino]imidazole-4-carboxamide = 5-[(5-phospho-1-deoxy-D-ribulos-1-ylimino)methylamino]-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide</text>
            <dbReference type="Rhea" id="RHEA:15469"/>
            <dbReference type="ChEBI" id="CHEBI:58435"/>
            <dbReference type="ChEBI" id="CHEBI:58525"/>
            <dbReference type="EC" id="5.3.1.16"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 8 10">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 4/9.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 8 10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 8 9">Belongs to the HisA/HisF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.16" evidence="8 10"/>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94003">
        <property type="protein sequence ID" value="PRC94003"/>
        <property type="gene ID" value="S2091_1176"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00009"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003949">
        <property type="term" value="F:1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04732">
        <property type="entry name" value="HisA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01014">
        <property type="entry name" value="HisA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006062">
        <property type="entry name" value="His_biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006063">
        <property type="entry name" value="HisA_bact_arch"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044524">
        <property type="entry name" value="Isoase_HisA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023016">
        <property type="entry name" value="Isoase_HisA-like_bact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43090">
        <property type="entry name" value="PTHR43090"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00977">
        <property type="entry name" value="His_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="SSF51366"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00007">
        <property type="entry name" value="TIGR00007"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8 9" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="8 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8 9" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="7 8 10" id="KW-0413">Isomerase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="8"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="8">
        <location>
            <position position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC94003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="256" mass="27445" checksum="DE4E5AF0B082E482" modified="2018-07-18" version="1">MLLIPAIDLKDGHCVRLKQGDMNQATVFSEDPGEMALHWLQQGARRLHLVDLNGAFAGKPKNEAAVKSIIKMVQWYAEENDLDEIPIQLGGGIRDLDTIDRYLNNGLSYIIIGTAAVKSPGFLHDACSAFPGQIIVGLDAKDGKVATDGWSKLSGHEVIDLAKKFEGYGVESIVYTDIGRDGMMGGVNIEATVKLAQAVSIPIIASGGVHVLADVEALCAVQDEGIEAVICGRSIYEGTLDLLTAQERADQLSETE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H250</accession>
    <name>A0A2S9H250_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glyoxalase-like domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1235</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94062">
        <property type="protein sequence ID" value="PRC94062"/>
        <property type="gene ID" value="S2091_1235"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004360">
        <property type="entry name" value="Glyas_Fos-R_dOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00903">
        <property type="entry name" value="Glyoxalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="1"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="125" mass="13565" checksum="1ABFD14DA73B7858" modified="2018-07-18" version="1">MFDHVKFGVSDYAASKTFFLKALESLGVAVAAEGVPTYGVELINPKSKTSLCLCQTEEKPAHLHLAFTAENRQQVDAFYRAALEAGGKDNGAPGLRQHYHANYYAAFVIGPDGHNVEVVCHEPEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2C2</accession>
    <name>A0A2S9H2C2_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7 9">50S ribosomal protein L16</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rplP</name>
        <name evidence="12" type="ORF">S2091_1308</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7 9">Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7 9">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7 8">Belongs to the universal ribosomal protein uL16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_040723969.1">
        <property type="nucleotide sequence ID" value="NZ_PUGF01000004.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94135">
        <property type="protein sequence ID" value="PRC94135"/>
        <property type="gene ID" value="S2091_1308"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01433">
        <property type="entry name" value="Ribosomal_L16_L10e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1170.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01342">
        <property type="entry name" value="Ribosomal_L16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016180">
        <property type="entry name" value="Ribosomal_L10e/L16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036920">
        <property type="entry name" value="Ribosomal_L10e/L16_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000114">
        <property type="entry name" value="Ribosomal_L16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020798">
        <property type="entry name" value="Ribosomal_L16_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12220">
        <property type="entry name" value="PTHR12220"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00252">
        <property type="entry name" value="Ribosomal_L16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00060">
        <property type="entry name" value="RIBOSOMALL16"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54686">
        <property type="entry name" value="SSF54686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01164">
        <property type="entry name" value="rplP_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00586">
        <property type="entry name" value="RIBOSOMAL_L16_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7 8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 7 8" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="7 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 7 9" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="2 7 9" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_L16" evidence="11">
        <location>
            <begin position="4"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004414"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00252"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PRC94135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="139" mass="15707" checksum="CA89EBF8BD6850D2" modified="2018-07-18" version="1">MLQPARRKYRKEQKGRNKGISHSRGTAVSFGEFGLKAIGRGRITARQIEAARRAMTRHIKRGGRIWIRIFPDKPISQKPAEVRMGNGKGNPEYYVAEIQPGKMLYEMDGVDETLAREAFRLAAAKLPLLTTFVVRQVGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2G4</accession>
    <name>A0A2S9H2G4_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">DNA polymerase IV</fullName>
            <shortName evidence="12">Pol IV</shortName>
            <ecNumber evidence="12">2.7.7.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">dinB</name>
        <name evidence="14" type="ORF">S2091_1345</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11 12">
            <text>a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="12">Binds 2 magnesium ions per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 12">Belongs to the DNA polymerase type-Y family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="12"/>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94172">
        <property type="protein sequence ID" value="PRC94172"/>
        <property type="gene ID" value="S2091_1345"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006261">
        <property type="term" value="P:DNA-templated DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009432">
        <property type="term" value="P:SOS response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd03586">
        <property type="entry name" value="PolY_Pol_IV_kappa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01113">
        <property type="entry name" value="DNApol_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036775">
        <property type="entry name" value="DNA_pol_Y-fam_lit_finger_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017961">
        <property type="entry name" value="DNA_pol_Y-fam_little_finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022880">
        <property type="entry name" value="DNApol_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024728">
        <property type="entry name" value="PolY_HhH_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001126">
        <property type="entry name" value="UmuC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00817">
        <property type="entry name" value="IMS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11799">
        <property type="entry name" value="IMS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11798">
        <property type="entry name" value="IMS_HHH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100879">
        <property type="entry name" value="SSF100879"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="SSF56672"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50173">
        <property type="entry name" value="UMUC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 12" id="KW-0227">DNA damage</keyword>
    <keyword evidence="10 12" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5 12" id="KW-0235">DNA replication</keyword>
    <keyword evidence="12" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9 12" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="8 12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 12" id="KW-0515">Mutator protein</keyword>
    <keyword evidence="4 12" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 12 14" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="UmuC" evidence="13">
        <location>
            <begin position="10"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="active site" evidence="12">
        <location>
            <position position="130"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="14"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="129"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="site" description="Substrate discrimination" evidence="12">
        <location>
            <position position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022457"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00024632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="PRC94172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="387" mass="42611" checksum="9767D741E58F386D" modified="2018-07-18" version="1">METSLINRRIAHLDMDAFYASVELISYPELRGKPVAIGGRNEHRPILLADGTRQFSRLADYVGRGVLTTSTYEARALGVFSGMGTMKAAKLAPEAILLPVNFDAYRHYSRLFKAAVASVVSQIEDRGIDEIYLDLSNEVGETVELAQRIKNAVFEATGLSCSIGIAPNKLLAKICSDLEKPNGLTVLSMSDIPTRIWPLHVRKINGIGPKAAQKLEALGVNTIAQLAEMDTSILQEEFGRTYAIWLNEVAHGIDRREVITESETKSISRETTFERDLHARHDRAVLSEIFTSLCSKLAEDLQRKGYLSRTIGIKLRYDDFKSVTRDLTLPEPTADSLLIRQAAGACLKRVPLEKRLRLLGVKASGLVGVDEVPAGGLAVGRQLELDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2M1</accession>
    <name>A0A2S9H2M1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0831</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94210">
        <property type="protein sequence ID" value="PRC94210"/>
        <property type="gene ID" value="S2091_0831"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="70"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="100"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="126" mass="13250" checksum="E0285780C14EA8A4" modified="2018-07-18" version="1">MLPAFLSYAADDIEEVRTQATKQYLQEQGLISGYLTGSSVGGNAPMMTMQSTIGSGIGKPLFFAALQNSSAGHAVFASMPIILLILAISGGARQGEESDLVRYGLLMVGLVAIVIVLTAMVLVFYC</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2X1</accession>
    <name>A0A2S9H2X1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0945</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94324">
        <property type="protein sequence ID" value="PRC94324"/>
        <property type="gene ID" value="S2091_0945"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="50" mass="5101" checksum="46988B1206CCA3DF" modified="2018-07-18" version="1">MNATAKVIGLDIAELLSDFPSEPTLSTVPQRGAPIAQLIDVTSGCITASS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H322</accession>
    <name>A0A2S9H322_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0887</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94266">
        <property type="protein sequence ID" value="PRC94266"/>
        <property type="gene ID" value="S2091_0887"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="125" mass="14723" checksum="A566CECAF2AACE71" modified="2018-07-18" version="1">MNLVHAPATKKSIADFDDAPIYQTQFKFMSVSEHLNRIVQRIKNFNNKTSNQNNEQPERCSMLYFSVDAKRITEARRLIISMCRDKLIFMRVKPMQHATTMQVELFLKTSVMQHVQEMMESSFQC</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H328</accession>
    <name>A0A2S9H328_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0991</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94370">
        <property type="protein sequence ID" value="PRC94370"/>
        <property type="gene ID" value="S2091_0991"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="116" mass="12495" checksum="C0C1F48252050760" modified="2018-07-18" version="1">MIINLESVADVGFAVRATRRSSGIRIDDMAGICKVSKQFVSDVEHGKETVQMGLTLKMLSDLGIRVFLDIPPSAEQMFTELKKSGGLKPAGFATTAKIKRSGGVDPLTPASRTRSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3B1</accession>
    <name>A0A2S9H3B1_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RNA polymerase-binding transcription factor DksA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">dksA</name>
        <name evidence="8" type="ORF">S2091_1068</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Interacts directly with the RNA polymerase.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the DksA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94447">
        <property type="protein sequence ID" value="PRC94447"/>
        <property type="gene ID" value="S2091_1068"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00926">
        <property type="entry name" value="DksA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012784">
        <property type="entry name" value="DksA_RNA_pol-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037187">
        <property type="entry name" value="DnaK_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000962">
        <property type="entry name" value="Znf_DskA_TraR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020458">
        <property type="entry name" value="Znf_DskA_TraR_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01258">
        <property type="entry name" value="zf-dskA_traR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109635">
        <property type="entry name" value="SSF109635"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02420">
        <property type="entry name" value="dksA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01102">
        <property type="entry name" value="ZF_DKSA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51128">
        <property type="entry name" value="ZF_DKSA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="DksA C4-type" evidence="7">
        <location>
            <begin position="71"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="dksA C4-type" evidence="6">
        <location>
            <begin position="114"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00510"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC94447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="151" mass="17153" checksum="FBD72FB285964DF6" modified="2018-07-18" version="1">MATKTTKTSAASNKPASIITEEELLKMGEKDYMNEAQLAFFKARLQQLEKDLLKNADETTEHLRETVLVPDPADRATIEEEHALELRTRDRERKLLKKVQQSIGLIDSGEYGWCEETGEPIGVARLLARPTANLSLEAQQRRELKQKLYGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3E4</accession>
    <name>A0A2S9H3E4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative phosphosugar isomerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0507</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94504">
        <property type="protein sequence ID" value="PRC94504"/>
        <property type="gene ID" value="S2091_0507"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097367">
        <property type="term" value="F:carbohydrate derivative binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901135">
        <property type="term" value="P:carbohydrate derivative metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05008">
        <property type="entry name" value="SIS_GlmS_GlmD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05009">
        <property type="entry name" value="SIS_GlmS_GlmD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035466">
        <property type="entry name" value="GlmS/AgaS_SIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035490">
        <property type="entry name" value="GlmS/FrlB_SIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001347">
        <property type="entry name" value="SIS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046348">
        <property type="entry name" value="SIS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01380">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53697">
        <property type="entry name" value="SSF53697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51464">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="SIS" evidence="2">
        <location>
            <begin position="26"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="domain" description="SIS" evidence="2">
        <location>
            <begin position="190"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="336" mass="35196" checksum="EF2179C048B81DCE" modified="2018-07-18" version="1">MHEEACSSAGFVATQLTQEGARFADLGAALRATPPTSVLTIARGSSDHAAAYAAYLIMSRLGRIVASLPMSLVTLMNAPLHAKDALAIAISQSGQSPDVIEPIRYFREGGATTVALVNDASSPLACAAEWCLPLHAGAEISVAATKSFITSLVAAAQLAGHWHNDPEFLAALAVLPAALHAATEIDWAEAIDVLTPANNIMVVGRGISFPVALEAALKFKETSAIQAEAFSGAEIKHGPMALIDEGYPLMIFATRGPTQAGLIKLAEEMRGRGARVLLAAPADIRERNLTIPVAATPDLDPIVAIQAFYVMAAKLSLARGLNPDKPRHLSKVTKTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3G7</accession>
    <name>A0A2S9H3G7_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">S2091_0514</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94511">
        <property type="protein sequence ID" value="PRC94511"/>
        <property type="gene ID" value="S2091_0514"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029151">
        <property type="entry name" value="Sensor-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103190">
        <property type="entry name" value="SSF103190"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="10" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="302"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="9">
        <location>
            <begin position="389"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="332"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC94511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="622" mass="69258" checksum="CB61A511A2EB0070" modified="2018-07-18" version="1">MHAINNPFVHFNSFRWQSAVLNYLNAIVISLIVIIAVLSLTYDYQLAENQVNSETHNLASSLVISIDGLLDTIDIALLDTADELVALQASDTHDHAIIDRNLKEERERLPGHVDLHATDEKGDMIYGKDPEQSVVNVADRPYFTSIRNHPDSGLYISTPIQGRYSHKWIWLFSRRIHKSDGSFGGVIAASIPIDEIKSMLGRHIALPKGGSIALRNKTLESIARVVFGIPNSIPIGDKRISDAYLAAAKKNPLEGTYISDSASADPISKTYSYVQSQKYGFIILVAIPREAAFAGWKKQMWVEIGIVSVFIFCAVVFVHFIRRAWQNQERDMLTIKESRDALQALNNELEERVHTRTQELSETLSHLRVTQNDLMQSEKLASLGFMVAGVSHEINTPIGNAVMLTSTLENHVTQLDQQIHTGNLSRPSLLSWIESTNDMVKLLERSVNRVAELVKNFKNLALDQTSECRRTFDLSHEIHSVIEVLRPNFKGHVIERNIPDHIKCDSYPEVFNQVVTNLIQNASLHAFEGRSEGRIVVTAIVDKGKVELTVADDGIGMNEATLVRIFDPFFTTKLGKGGSGLGLAFCYRIVTNILAGELRAISTKDVGSQFILTMPLNAPGAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3U6</accession>
    <name>A0A2S9H3U6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Lipocalin-like domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0634</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94631">
        <property type="protein sequence ID" value="PRC94631"/>
        <property type="gene ID" value="S2091_0634"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024311">
        <property type="entry name" value="Lipocalin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13924">
        <property type="entry name" value="Lipocalin_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015392794" evidence="1">
        <location>
            <begin position="28"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="domain" description="Lipocalin-like" evidence="2">
        <location>
            <begin position="36"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="171" mass="18585" checksum="A73171FA74C4C32D" modified="2018-07-18" version="1">MSITSKCATSISMAAPLLMMGSAVAVAPEQLLSLEGTWVMISAYELLADGTRTTNYGEHPNGLLMVDKDGRYSIQIFRPNRAKFSSGDKTRGTPEEYRDAVLGSSTHTGQVAIDPTKGKLIFKISSASYANWEGTQQVRDYTFKDGILTYQVPASASGNGTIAYSIWQRVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3W4</accession>
    <name>A0A2S9H3W4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0672</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94669">
        <property type="protein sequence ID" value="PRC94669"/>
        <property type="gene ID" value="S2091_0672"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="93" mass="10884" checksum="4CB5F56A2B8796FA" modified="2018-07-18" version="1">MTLIIDPPIRVKLREKHQVSEVEVRECIRNTSGKYLMDDREEHKTNPPTYWFLSETDNGRMLKIVFMLKGSDMILKSAFEPRPSDIKTFNKAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3Z3</accession>
    <name>A0A2S9H3Z3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Virulence protein RhuM family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0705</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94702">
        <property type="protein sequence ID" value="PRC94702"/>
        <property type="gene ID" value="S2091_0705"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011204">
        <property type="entry name" value="Virulence_RhuM-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13310">
        <property type="entry name" value="Virulence_RhuM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="113" mass="13052" checksum="A73001B61706D99A" modified="2018-07-18" version="1">MFSSNDGKVRIECRFENDTLWLSQAMICDLYGKAKGTINGHVKNIFEEGELDENSVVRFYRTTAADGKNYRVQYFSLPLVLAVGYRVRSVRGTQFRQWATPLLEEYIIKGFGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H481</accession>
    <name>A0A2S9H481_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0679</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94676">
        <property type="protein sequence ID" value="PRC94676"/>
        <property type="gene ID" value="S2091_0679"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043749">
        <property type="entry name" value="DUF5694"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18950">
        <property type="entry name" value="DUF5694"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="354" mass="39057" checksum="1266F659C916683E" modified="2018-07-18" version="1">MGKWTNWIWGLIATFIATFPFTTQAQVNLTALDRDMVGPRAQVLVLGTVHLSELPESFNPASLQSVLDRLAAFKPDIITIEALSGEECDLAARHPAKYGPDYCAPTDAAQAATKLDVPAAIAEVDKTFKAWPAQPTPAQRRRLAALFLAANDRASAYVQWLQLPEAERRAGDSLDTALVEMLGRIGTRNNENYQLGARLAARLGLQRVYAVDNHTGDNIDFTDRQTVGQVLAAAWAAGKGELNEHEKREKVLLQAPDLLPLYRSVNDPDYLRVLAEVNVSAALRAKSPEGYPQIWVAGWEVRNLRMVANVHETFRERPGARVLSIVGASHKPWFDHWLGQLPGVDIVDVEGMLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4B3</accession>
    <name>A0A2S9H4B3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alginate lyase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0014</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="SMR" id="A0A2S9H4B3"/>
    <dbReference type="EnsemblBacteria" id="PRC94819">
        <property type="protein sequence ID" value="PRC94819"/>
        <property type="gene ID" value="S2091_0014"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014895">
        <property type="entry name" value="Alginate_lyase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08787">
        <property type="entry name" value="Alginate_lyase2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="SSF49899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alginate_lyase2" evidence="1">
        <location>
            <begin position="77"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="279" mass="30349" checksum="978270FE98DAEADE" modified="2018-07-18" version="1">MRRLGFVQVHRMRDSRCGYTNKSLVAQPNSNKLMKINTLATSALTVLLAITSINALAAENKSSNTGVDVAKAPGENFDLSGYKLQLPVANGHSVVEVAPAMLRDYESNYFYTDKSSGAMVFSCPSNGATTRGSHYPRTELRSLSEWNFTDSHSLTATLAVTQQPDNRDLIVGQIHGDGKGSEALKLRWHNGDIVAGVKTSLNTTEIRSTIAKGIALGEQFTYSIVQQDHAVTVTVNGASQSFTYDASWDNETVYFKAGNYLQDNSTSGANGVVFFYKLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4C2</accession>
    <name>A0A2S9H4C2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Helix-turn-helix domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0024</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94829">
        <property type="protein sequence ID" value="PRC94829"/>
        <property type="gene ID" value="S2091_0024"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="36"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="95" mass="10559" checksum="7C82A259D2833F69" modified="2018-07-18" version="1">MNNKYIGSNFDDFLAEDGILDETTAVAVKRVLAWQISQEMKRQKLTKTSMAEKMHTSRAALNRLLDEKDTSLTLTTLSSAASALGKKLRLELVSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4H4</accession>
    <name>A0A2S9H4H4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Methyl-accepting chemotaxis protein (MCP) signaling domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_0079</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94884">
        <property type="protein sequence ID" value="PRC94884"/>
        <property type="gene ID" value="S2091_0079"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004089">
        <property type="entry name" value="MCPsignal_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00015">
        <property type="entry name" value="MCPsignal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00283">
        <property type="entry name" value="MA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50111">
        <property type="entry name" value="CHEMOTAXIS_TRANSDUC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0807">Transducer</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="177"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="domain" description="Methyl-accepting transducer" evidence="4">
        <location>
            <begin position="261"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="275"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC94884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="528" mass="56106" checksum="A76C36E22887CBF7" modified="2018-07-18" version="1">MSMSIKRRIWALPATATVIFGIGLAVSIYFSTIAISSINTTETIDYPLLDQTKSLITDVNGLVKALQEAVSEGDKKRLDAIELSAKNIRDNIKNLGQIVGQQNTATRLTKEFEAYYSPALGVARMMMSLDEGDPMPLIGKMQSSLNVVQADLVKTLETAKKQFKTGVERSGDSVTNVMTTTILVAVLVILTLGGVSFVVVRGIWQQLGGEPEYTRDIAVAIAAGDLSMTIETDANDTGSLLVALKEMKSKLELMVSDIKISAETIKLASSEIASGNNDLSSRTESQANSLQETSSSMTSLSDTVKQNADSAKQANHLVDIASDVAVKGGQVVSQVIGTMSEINGSSKKIVDIITVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVASEVRNLAQRSAAAAKEIKTLISDSVEKVTQGSQLVDQAGKTMGEIVDSVKRVSDIMKEISSASQDQSTGIQEIGRAIEHMDEMTQQNSAMVEEAASAAASMNSEAEKLTQALDVFKLTEAGVSSSRLGNSPNRMLKITNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4M2</accession>
    <name>A0A2S9H4M2_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Probable lipid II flippase MurJ</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">murJ</name>
        <name evidence="10" type="ORF">S2091_0088</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8 9">Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.</text>
    </comment>
    <comment type="pathway">
        <text evidence="8">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell inner membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8 9">Belongs to the MurJ/MviN family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94893">
        <property type="protein sequence ID" value="PRC94893"/>
        <property type="gene ID" value="S2091_0088"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015648">
        <property type="term" value="F:lipid-linked peptidoglycan transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd13123">
        <property type="entry name" value="MATE_MurJ_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02078">
        <property type="entry name" value="MurJ_MviN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004268">
        <property type="entry name" value="MurJ"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03023">
        <property type="entry name" value="MurJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002869">
        <property type="entry name" value="MviN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01806">
        <property type="entry name" value="VIRFACTRMVIN"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01695">
        <property type="entry name" value="murJ_mviN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="2 8 9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 8 9" id="KW-0133">Cell shape</keyword>
    <keyword evidence="8 9" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="7 8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 8 9" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="8 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="90"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="134"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="161"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="186"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="317"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="355"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="387"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="412"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="445"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="485"/>
            <end position="506"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR002869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC94893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="516" mass="55780" checksum="4AC7C252ACB62768" modified="2018-07-18" version="1">MNLLKTLATMSSMTMLSRITGLIRDMLFAKLIGASAYSDAYYIAFRIPNLLRRVFAEGAFSQAFVPILAEYKNQQGHDATKSLVNSVATILTWCLLITSFIGVVAAPLFVYALASGFVSNPEKFNVTVVMTRIMFPYIGMISLVALAGGILNTWHEFKIPAFSPVLLNVSSIGCAFLLAPQLAQPVYAFAIAVVIGGVLQLAIQIPALIKIGMLPKISLKPIAAFQDPAVKRILKNMGPAIFAVSASQISILINSNIASQLATGSVSWLYCADRLMEFPTALLGVTLGTVLLPSLSKANSVGDHEEYSSLLDWGLRLTFLLALPAAVGLATLSVPLTTVLFHYGKFDGLAVIQTSHALVAYGIGLIGLILVKILAPGFYAKQNIKTPVKIAIGVLVATQIMNSIFVPSLAHVGLALSVGLGACLNAGFLFALLKRHGIYKPQPGWLFFFIKQTGALLLMAAVALYLNSQFDWVALQKHYYLRALYLTGVLSACMFVYFVSLFAMGFRFADFRRISK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4U9</accession>
    <name>A0A2S9H4U9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ABC transporter, phosphonate, periplasmic substrate-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0158</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94963">
        <property type="protein sequence ID" value="PRC94963"/>
        <property type="gene ID" value="S2091_0158"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015660673" evidence="1">
        <location>
            <begin position="22"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="270" mass="30002" checksum="AD3A852BFDEEA809" modified="2018-07-18" version="1">MFYKRICCVVFLIFLSHTVSAQELLFAVNEGVTYQDDGLPSERFKLLIKMLSKELKRPIKLHTISHYSDFEHELAIEHIDLAFIHPGNVGLIAAKSGNYFGLATAKDFTDYRARVMVKADSPLKSMADLRGKKIGVPSLESITTVMFTASLRELGIADPAKQFTPTRYQDAVPFMLDYGFVDAGVTGSGAVAKNWIAKGGRVIAETKPVPIKQFLMSRRFSAEEREKVQNLLLKLNETDDGKAALTGLHITGFVPWNTTVMDEASKRLGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4V2</accession>
    <name>A0A2S9H4V2_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">3-deoxy-manno-octulosonate cytidylyltransferase</fullName>
            <ecNumber evidence="3">2.7.7.38</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">CMP-2-keto-3-deoxyoctulosonic acid synthase</fullName>
            <shortName evidence="3">CKS</shortName>
            <shortName evidence="3">CMP-KDO synthase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">kdsB</name>
        <name evidence="4" type="ORF">S2091_0101</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>3-deoxy-alpha-D-manno-oct-2-ulosonate + CTP = CMP-3-deoxy-beta-D-manno-octulosonate + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:23448"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <dbReference type="ChEBI" id="CHEBI:85986"/>
            <dbReference type="ChEBI" id="CHEBI:85987"/>
            <dbReference type="EC" id="2.7.7.38"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Nucleotide-sugar biosynthesis; CMP-3-deoxy-D-manno-octulosonate biosynthesis; CMP-3-deoxy-D-manno-octulosonate from 3-deoxy-D-manno-octulosonate and CTP: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the KdsB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.38" evidence="3"/>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94906">
        <property type="protein sequence ID" value="PRC94906"/>
        <property type="gene ID" value="S2091_0101"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00358">
        <property type="reaction ID" value="UER00476"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008690">
        <property type="term" value="F:3-deoxy-manno-octulosonate cytidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033468">
        <property type="term" value="P:CMP-keto-3-deoxy-D-manno-octulosonic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009103">
        <property type="term" value="P:lipopolysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02517">
        <property type="entry name" value="CMP-KDO-Synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00057">
        <property type="entry name" value="KdsB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003329">
        <property type="entry name" value="Cytidylyl_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004528">
        <property type="entry name" value="KdsB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02348">
        <property type="entry name" value="CTP_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00466">
        <property type="entry name" value="kdsB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 3" id="KW-0448">Lipopolysaccharide biosynthesis</keyword>
    <keyword evidence="3 4" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3 4" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC94906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="266" mass="29282" checksum="877F0D791BC2D5B8" modified="2018-07-18" version="1">MTVLNTTTFNGRNNFYVIIPARLASTRLPNKPLADLAGKPMIVRVAERAKLSGAELVVVACDDVSIVEACQQYGITAYLTRTDHQSGTDRIAEVAKMLGLPDDAVIVNVQGDEPLIEPALITATAAQINNGVQMSTAAHPITSAEEAFNPNVVKVVLDKLGRALYFSRATIPWNRDAFAASKEVMPLDYRVFRHIGLYAYTQAFLQKYSTLEVAPLEQCEVLEQLRVLWNGYPIAVYVTPTMPLGGVDTPEDLLRVQQHYLQHGIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H530</accession>
    <name>A0A2S9H530_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">SSADH: succinate-semialdehyde dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_0290</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95095">
        <property type="protein sequence ID" value="PRC95095"/>
        <property type="gene ID" value="S2091_0290"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009013">
        <property type="term" value="F:succinate-semialdehyde dehydrogenase [NAD(P)+] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009450">
        <property type="term" value="P:gamma-aminobutyric acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010102">
        <property type="entry name" value="Succ_semiAld_DH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01780">
        <property type="entry name" value="SSADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
        <property type="entry name" value="ALDEHYDE_DEHYDR_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldedh" evidence="3">
        <location>
            <begin position="27"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC95095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="490" mass="52570" checksum="7F706BDF57054A18" modified="2018-07-18" version="1">MLPVTGLSLNDPTLFKTQIFINDEWHTSDNVFEVRNPANGKLLANVANANVQQAQSAIDAAAVAFPAWAAKTGKQRAEVLRKWFDLILQHTDDLAHILTAEQGKPIAEARGEVVYAASFVEWFAEEAKRVTGDVMSSTWTDKRMVVIKQPIGVCAAITPWNFPLGMITRKVAPAIAAGCSIVIKPAEQTPLSALALVELARRAGLPAGVLSVVTADSQNSIEIGKLLCASKTVRHISFTGSTPVGRILMQQSAPTVKKMALELGGHAPFIVFDDADLDAAVEGAVQSKYRNAGQTCVCTNRFYVHSSLYDAFVSKLAAKVQAIQVGDGMTEGVLQGPMIDGQAVEKVAQHVQDAISKGAKLVIGGKSHALGGYFYEPTLLSNVSNDMQIMSEETFGPVAAVMKFETEAEVIAAANNTDFGLASYFFSRDIGRIWRVAEKLEYGMVGINTGLISNEVAPFGGVKQSGLGREGSSYGMDEYLEMKYLCMGGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H569</accession>
    <name>A0A2S9H569_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Sel1 repeat</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0325</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95130">
        <property type="protein sequence ID" value="PRC95130"/>
        <property type="gene ID" value="S2091_0325"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC95130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="265" mass="28911" checksum="C7050D5303C58FD2" modified="2018-07-18" version="1">MCIRTSDDPSNQALNIVQSTKAWSPRFSNVTSASQPVEAKTTSSDEGEIFGLNLDGKTVAQYVREYYGAADKGDPKAAFKIYQAELICDGLKSNERAQSTKGEGWLNGADMRKAQKLCDGFNGNRNELLKYIAQAAKGGVADAQALFINTPPDWVLDGPLIPDTTNPHVKEWYEQAIGYLNQAATQGNQMAMLDLARIYKNGDGVQKNLQMAATFEIAYFQIHKLPLSNPLVANITNQLTPDQVREATSAAQVYVAASDNANNNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5C3</accession>
    <name>A0A2S9H5C3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0328</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95133">
        <property type="protein sequence ID" value="PRC95133"/>
        <property type="gene ID" value="S2091_0328"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC95133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="29" mass="3133" checksum="B55C218D78F09A53" modified="2018-07-18" version="1">MKIRTNSAGVTFKPIPMKCEAHKGLDSGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5G8</accession>
    <name>A0A2S9H5G8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Bacterial extracellular solute-binding protein, family 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0311</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95116">
        <property type="protein sequence ID" value="PRC95116"/>
        <property type="gene ID" value="S2091_0311"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015580843" evidence="1">
        <location>
            <begin position="26"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC95116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="308" mass="35413" checksum="C4E07E816D5F8605" modified="2018-07-18" version="1">MFNPMLKIGRLLPLLAFFICEMACSQTEVIYPSSVSNIDSRHRDLIELLTMSLEKTIPEYGEYTLTPSKLKMNEARALTELQNNELVNVVWSPTSEAMETQFIPIRVPLRKGLLGLRIALINSKNKAAIDTIKTVADLRKFSIGQGIGWGDVSVYQANVIPVETANYDALFSMTAHDRFYLFPRGITEIFSEFELRKASFPELEIEKNLMIYYPWPYYFFVNKNNKKLADRISLGLERMITDGSFNRIFMKYNGAAIRSANLNKRRIIQLENPQLPKKTPLDARYWFFPSLIKSAVLNQSQHGNIHNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5J2</accession>
    <name>A0A2S9H5J2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Methyl-accepting chemotaxis protein (MCP) signaling domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_0450</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95255">
        <property type="protein sequence ID" value="PRC95255"/>
        <property type="gene ID" value="S2091_0450"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024478">
        <property type="entry name" value="HlyB_4HB_MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004089">
        <property type="entry name" value="MCPsignal_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12729">
        <property type="entry name" value="4HB_MCP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00015">
        <property type="entry name" value="MCPsignal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00283">
        <property type="entry name" value="MA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50111">
        <property type="entry name" value="CHEMOTAXIS_TRANSDUC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0807">Transducer</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="domain" description="Methyl-accepting transducer" evidence="4">
        <location>
            <begin position="277"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="562"/>
            <end position="588"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC95255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="588" mass="62248" checksum="0F9413206A103F84" modified="2018-07-18" version="1">MNLSKIKVGKRLGLGFALVLAFLIVVTMLGITRMSQIQDRLDKIVTVSNVETRLIIDMRAIVYDRMVSLRNLTLLNDIDDMGPDLAKIKEQSDKYAAAEAKLAKMFEDESSTTAEEKSMLGKLKDQATAAAPLPAKAQELGLANNPEVATITLIKKLRPIQKKWLDTLDDMTTLEDKLNAGVAHEANSAFSTARTLMLLLGGLALITGVAAAVIITRSLLKQLGGEPDYASQIASQIAAGDLAAMIETKPGDETSLIAEMKTMRDSLVNIVGQVRVRTDTIATASSEIAMGNLDLSSRTEQQASSLEKTSSAMKELTKTVKLNADNAREANQLALSASEVARHGGTVVAQVVDTMSAINESAKKIEDIISVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVASEVRNLAQRSAVAAKEIKGLITTSVEKVGVGTKLVGQAGVTINQIVASVKQVNDIIAEISHASQDQSADIEGINHSVIDMDGMTQQNAALVEQAAAAAQSLQDQAAELAKVVSIFKLTTNAPLNFAKKTAPSAARPEVKLTQVKAKSPVAEIKSAAKSSIKSLPAAKSTAKKNAAVDGNDWEEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5J3</accession>
    <name>A0A2S9H5J3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">3-oxoacyl-(Acyl-carrier-protein) synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_0341</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95146">
        <property type="protein sequence ID" value="PRC95146"/>
        <property type="gene ID" value="S2091_0341"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd00834">
        <property type="entry name" value="KAS_I_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000794">
        <property type="entry name" value="Beta-ketoacyl_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11712">
        <property type="entry name" value="PTHR11712"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PKS_KS" evidence="3">
        <location>
            <begin position="27"/>
            <end position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC95146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="400" mass="41436" checksum="44420DDA5FA04BC1" modified="2018-07-18" version="1">MLYLNECGIVCALGNTHSAIKQQLLDLAQSGVKPTEAWSAGRCLALGRVDAQVDAELPSMDAWPTAQLSRNNQMALAALAQIRPAVDAVIARFGSDRIGVVIGTSTSGIAGTESALRQFVVDGTFPADFHYGQQEMGSPASMLATELGVTGPAYAHSSACSSSAKALASAARLINMGLCDAVLCGGVDTLCAFTVAGFSALESVSVEQCNPLSANRNGINIGEGAALFLMTREPNLGATSVALCGWAETSDGYHISAPDPAGGGARLSMNQALQRAKLQPSQIDYINMHGTATRQNDAMEAKVIHELFGPDVAVSSTKSFTGHTLGAAAAIEAALCWLAMQDDNADGKLPPHLWDGVQDPTLPVLNVAAPGARLGRPIKWALSNSFAFGGSNATLILGRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5J6</accession>
    <name>A0A2S9H5J6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative permease YjgP/YjgQ family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_0447</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95252">
        <property type="protein sequence ID" value="PRC95252"/>
        <property type="gene ID" value="S2091_0447"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030923">
        <property type="entry name" value="LptG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005495">
        <property type="entry name" value="LptG/LptF_permease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33529">
        <property type="entry name" value="PTHR33529"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03739">
        <property type="entry name" value="LptF_LptG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04408">
        <property type="entry name" value="LptG_lptG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="65"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="103"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="296"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="323"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="355"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC95252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="379" mass="42475" checksum="D5ED418023323825" modified="2018-07-18" version="1">MMNTLEKYFAREISRSVLFVLLAFVALLAFFDIVNEVKSVGIGGYTLANALYYVFLGIPGNVYEYMPLAALIGTIFVMAQFASRSEFTIMRVSGFSTFQAIKMLLKIGLAFVVVTFVFGELFAPYTFKMAERYKISVMPSSHKQDFQSGLWTKDLIRTGGLTGEVIGSRFLNVNIVDPSGKLIGIDFYDLDTQFRLIKKVTAATAEYQGGSVWRLSHAEETYFPLSLNDTEMTPVEVKELDHVDLISEITPAILLASSADNDTDRMSAYDLKLYSKHLVDNKQSAEKFEIAFWKKVIYPFAVLVMMALALPFAYLHFRSGGVSLKIFTGIMIGVGFYLLNNVFAHIGLLHTWPPFVTAVLPSLLFLAAAMMALWWVENN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSQ2</accession>
    <name>A0A2S9GSQ2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4552</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000037">
        <property type="protein sequence ID" value="PRC90726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90726">
        <property type="protein sequence ID" value="PRC90726"/>
        <property type="gene ID" value="S2091_4552"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015485163" evidence="1">
        <location>
            <begin position="27"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="223" mass="25907" checksum="45B9F55286DCC443" modified="2018-07-18" version="1">MKINDGKLRAVALAITCLAVSLPGQAAPMGFKDSWMVMGDFDTNWRDLYTNYAFTPQDAFGVDALYMRSDDKLQTLDLVDATYTRLIQRWNLPDAQANFWFMGGLGEARTYDQRSGIFDTKLMVSPGLQLDYETTRVYFAANTQLYRAEQINHDMASLRTGFSFYETEFDETQPWFIIEARRMHDLSDKTEITPMLRLINKDYFIEAGVNNSRQFRFNFMYTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSU7</accession>
    <name>A0A2S9GSU7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Fe2+ transport system protein A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_4516</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FeoA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000036">
        <property type="protein sequence ID" value="PRC90768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90768">
        <property type="protein sequence ID" value="PRC90768"/>
        <property type="gene ID" value="S2091_4516"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046914">
        <property type="term" value="F:transition metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007167">
        <property type="entry name" value="Fe-transptr_FeoA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038157">
        <property type="entry name" value="FeoA_core_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008988">
        <property type="entry name" value="Transcriptional_repressor_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04023">
        <property type="entry name" value="FeoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00899">
        <property type="entry name" value="FeoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50037">
        <property type="entry name" value="SSF50037"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FeoA" evidence="3">
        <location>
            <begin position="13"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC90768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="98" mass="10644" checksum="1985719F9234E51D" modified="2018-07-18" version="1">MTTSTLNLATSSLSLDQLKVGESGFVGKINQLTSAIAHHDPHLARRLMEIGFIPGEPLQVLHKGFFGGEPIAVRIGHSTFALRRFEAALISVITHIEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSZ2</accession>
    <name>A0A2S9GSZ2_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF695 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4488</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000035">
        <property type="protein sequence ID" value="PRC90825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90825">
        <property type="protein sequence ID" value="PRC90825"/>
        <property type="gene ID" value="S2091_4488"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016097">
        <property type="entry name" value="DUF695"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05117">
        <property type="entry name" value="DUF695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF695" evidence="1">
        <location>
            <begin position="10"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="158" mass="17825" checksum="5C63D4AB300ACAE8" modified="2018-07-18" version="1">MNQENQSLENQWSRFECVANGESSVIGCMFPGEINVDKAAYPNHVFIGYGYGEEDSGRLPNAEEWAKIDSIERTISGDLKKHDLGLLLFTIANDGYYQWNIYSKFGDKTALTLIETFKNSSTVPKIDVFDYSSSFDSNWNAYEPIREIIRKALGKATG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GT12</accession>
    <name>A0A2S9GT12_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Phage integrase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_4426</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000034">
        <property type="protein sequence ID" value="PRC90845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90845">
        <property type="protein sequence ID" value="PRC90845"/>
        <property type="gene ID" value="S2091_4426"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044068">
        <property type="entry name" value="CB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002104">
        <property type="entry name" value="Integrase_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010998">
        <property type="entry name" value="Integrase_recombinase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00589">
        <property type="entry name" value="Phage_integrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51900">
        <property type="entry name" value="CB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51898">
        <property type="entry name" value="TYR_RECOMBINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0229">DNA integration</keyword>
    <keyword evidence="3" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="2 4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core-binding (CB)" evidence="6">
        <location>
            <begin position="60"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="domain" description="Tyr recombinase" evidence="5">
        <location>
            <begin position="167"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC90845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="364" mass="41680" checksum="A81EC432D67D4A81" modified="2018-07-18" version="1">MRTRTKGIQSTANNGKIVNKEYRGKRVYARLGAVSQEEAEAWLRKEQTRIDNELEQGTQRNFAIAARKYLEDCERRKVRTLELIAYHITLALPYIGTKPLEAVHTGSLQTFCDSRINDDGVTPTTVNRTLEVVRSILNKAARVWRQENGLPWLVSAPLIEMLDETPRLPYPLAWEEQSRLFGELPAHLELMALFAVNTGLRDDNVCGLKWDWERYIPELKRSVFIIPAAEFKGNRQHVAILNDVAWKVVESCRGIHSDYVFTYRNEKKSLPANRVDTMNNTGWQKARSRVNLSQVRVHDLRHTFGQRLREAGVANEDRAVLMGHATSNMSEHYATPTISRLIEMSNLVTKTRDAMTLLRVVNGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GT36</accession>
    <name>A0A2S9GT36_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein-tyrosine-phosphatase</fullName>
            <ecNumber evidence="2">3.1.3.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_4377</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:10684"/>
            <dbReference type="Rhea" id="RHEA-COMP:10136"/>
            <dbReference type="Rhea" id="RHEA-COMP:10137"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:46858"/>
            <dbReference type="ChEBI" id="CHEBI:82620"/>
            <dbReference type="EC" id="3.1.3.48"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.48" evidence="2"/>
    <dbReference type="EMBL" id="PUGF01000033">
        <property type="protein sequence ID" value="PRC90884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90884">
        <property type="protein sequence ID" value="PRC90884"/>
        <property type="gene ID" value="S2091_4377"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004725">
        <property type="term" value="F:protein tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036196">
        <property type="entry name" value="Ptyr_pPase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016919">
        <property type="entry name" value="UCP029416_PTP"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029416">
        <property type="entry name" value="UCP029416_PTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52788">
        <property type="entry name" value="SSF52788"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC90884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="107" mass="12250" checksum="6B7DAC874852E672" modified="2018-07-18" version="1">MKRALFICTQNRLRSPTAEQIFSSWPNVETDSAGLGNDANVSLSPEQLAWADIIFVMEKTHRNKLSAKFKSHLNGKRVICLEIPDEYEFMQPELIRLLEAKAGKFLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GT47</accession>
    <name>A0A2S9GT47_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">HD domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4376</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000033">
        <property type="protein sequence ID" value="PRC90883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90883">
        <property type="protein sequence ID" value="PRC90883"/>
        <property type="gene ID" value="S2091_4376"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC90883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="167" mass="18535" checksum="B788454FE931F1BC" modified="2018-07-18" version="1">MGDVAFKALLFAREAHKDHVRKYSGNPYVDHLAEVAGITATVLTEDFAIASAWLHDCVEDCGIKLSAIYEEFGEKIGYGVEMLSDLETGNRAERKEASRKRLAGAEAWVQTIKCADLISNTSSIVKHDPNFAVIYLKEKRLLLDVLVKADPRLIELARSMSLSPRSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GT71</accession>
    <name>A0A2S9GT71_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4381</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000033">
        <property type="protein sequence ID" value="PRC90888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90888">
        <property type="protein sequence ID" value="PRC90888"/>
        <property type="gene ID" value="S2091_4381"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC90888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="171" mass="18645" checksum="FB7BD18C8983D99E" modified="2018-07-18" version="1">MNGVPPTRYNVTPVTADIVPVTAKLSFDSSLNVVDKSFDINAANILAENPVGSASYARLQNQGTSVAFVNDPEMNAMGLFNANTNDVTVNMALHSSPEEAASTIVHEATHQNGFFNGIPQITQYTEYQAFRNESLFQNGVRPSLDERLNIWNDFQSLCPDLPQGKYPFGGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTD4</accession>
    <name>A0A2S9GTD4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phage baseplate assembly protein V</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4269</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000031">
        <property type="protein sequence ID" value="PRC90973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90973">
        <property type="protein sequence ID" value="PRC90973"/>
        <property type="gene ID" value="S2091_4269"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006531">
        <property type="entry name" value="Gp5/Vgr_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013046">
        <property type="entry name" value="GpV/Gp45"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037026">
        <property type="entry name" value="Vgr_OB-fold_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04717">
        <property type="entry name" value="Phage_base_V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01644">
        <property type="entry name" value="phage_P2_V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phage_base_V" evidence="1">
        <location>
            <begin position="19"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="213" mass="22607" checksum="E241A619C167524C" modified="2018-07-18" version="1">MTSDLSDLLRLILNLIRFGSIAEVDYDAQKVRVLVGKNLTDWRPWATQRAGDTQTWWPPTKGEQVILFSPEGDFNQSILFPAVYSEHAKPPSTNPAHHTTKYPDGAIIQYDHEAHALTAILPSGSSALVKADKVTSDAKETLCTGNLTVAKNLIVNGMSSLNAGMAVLPGTDGAAASIQGKLNVSDDVIAKGISLTGHKHPVIALGADSGVAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTG2</accession>
    <name>A0A2S9GTG2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4274</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000031">
        <property type="protein sequence ID" value="PRC90978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90978">
        <property type="protein sequence ID" value="PRC90978"/>
        <property type="gene ID" value="S2091_4274"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC90978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="109" mass="12477" checksum="D55CFF4942655C30" modified="2018-07-18" version="1">MATRTKAISKKIDVNIVETTAVEKIIPILITGYQYGDYGNFIGEYQFEKNRDKEEIHCPPRTTLIPPPTDLPADKETVFDGEKWIIRNLEMPWLPDREIPADDEVSDGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTH5</accession>
    <name>A0A2S9GTH5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Prepilin-type N-terminal cleavage/methylation domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_4297</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the N-Me-Phe pilin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000031">
        <property type="protein sequence ID" value="PRC91001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91001">
        <property type="protein sequence ID" value="PRC91001"/>
        <property type="gene ID" value="S2091_4297"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009289">
        <property type="term" value="C:pilus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007155">
        <property type="term" value="P:cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001082">
        <property type="entry name" value="Pilin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00114">
        <property type="entry name" value="Pilin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0281">Fimbrium</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0488">Methylation</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC91001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="150" mass="15021" checksum="58845032658644F2" modified="2018-07-18" version="1">MNTQTTQKGFTLIELMIVIAIIGILAAIAVPQYQTYTVKSKFTEVVGATAPWKLAVELCALDTGALAACANANTTGEVGAAPAATGNLASVVTVANGTITATAVGAAGTPVNGLSGQTYILNPTLNAAGSATMITWVKNTASTCVTQSIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTK1</accession>
    <name>A0A2S9GTK1_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HTH cro/C1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4228</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000030">
        <property type="protein sequence ID" value="PRC91040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91040">
        <property type="protein sequence ID" value="PRC91040"/>
        <property type="gene ID" value="S2091_4228"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="12"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="99" mass="11002" checksum="7E226C648063A41F" modified="2018-07-18" version="1">MSYAEMIKTALKGRSVYAVSKLWGVNNMTLNRYIRGERMPDFVTAKKMAEEAGIDLADAFKLLAEEEQKRRGKLAKISEGFKKLLCAANVSWAMAPATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTK2</accession>
    <name>A0A2S9GTK2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Replication regulatory protein RepB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4219</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000030">
        <property type="protein sequence ID" value="PRC91031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91031">
        <property type="protein sequence ID" value="PRC91031"/>
        <property type="gene ID" value="S2091_4219"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="86" mass="9823" checksum="B892A71EB423CC99" modified="2018-07-18" version="1">MKQACDKFTLDFLTASRGRPPKVNALTAAQRQAQRRERLRNSGKSSLTVILPVELIDGLDKFVQFKGLSKDVVIERLIRSQLLRKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTS1</accession>
    <name>A0A2S9GTS1_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">S2091_4195</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="PUGF01000029">
        <property type="protein sequence ID" value="PRC91099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91099">
        <property type="protein sequence ID" value="PRC91099"/>
        <property type="gene ID" value="S2091_4195"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902531">
        <property type="term" value="P:regulation of intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01590">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6 14" id="KW-0418">Kinase</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3 8" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="63"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="198"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="13">
        <location>
            <begin position="265"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="11">
        <location>
            <begin position="597"/>
            <end position="817"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="12">
        <location>
            <begin position="861"/>
            <end position="974"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="12">
        <location>
            <begin position="1134"/>
            <end position="1250"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="500"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="8">
        <location>
            <position position="910"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="8">
        <location>
            <position position="1183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="PRC91099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="1255" mass="138975" checksum="A6AB02A3605E06E6" modified="2018-07-18" version="1">MAIGMKLTILKRLVPVVAVALMGVTLIASISQYMNNKVYDSTNYANVNVVPSLLLLGEMRKNYFLAWISAQQLFFSINGTEKETLISQISVYRRNVEDTFNKYEFNGCFGTPCFTDEEDKSLYFQEKALWAKFSDSLTQALAEISKNQQGQVKAQNIILETMALNGKLLDVLDQHLQYNAVISKRSADKAAIEKERAFYFLQFIGFVTFISIGAIGFFSIRSILRQLGGEPADAADIAAKLALGDLSPQIQLKPGDTTSLMAKIKQLINAMEKVANRADAVGRGNLADAVEVLSERDRLGQAINHMVVSLRTARIIDDRNNWLNTGNNQLAQALTGDFTPQQIANTALSTIGHYLGAGRGVLYRMRTDVGMLDVLGSYMYSEGENQQKTVKFGEGAIGQVAVEKNPIVLTNISRAAGDGTAPILTGTTNSPPHATYTYPILKENILLGVVEFSFLEQLSEIKLDYLNSALKIIASYLYVAEQRGQIHTLLTLSEQAGRDVRKQNDYLQEVNIRMEEQQQQLQQQAEELLQSNAQMEQQQQNLQQQSEELQQSNAQMEEQHQLLEHSNEVLRQSQTEIDEKAKQLELSNHYKSEFLANMSHELRTPLNAIILLSKMMMDNPDGHLRDSEIKRSEVIHRSGQDLLTLINDVLDLSKVDAGRIELNFVEISSNAIITELRDLFDSVAQNNGVEFIIQDQLNTKLNSDPGKISQIVRNLLSNAFKFTKQGSVTLRIQKIPNDQLPIRISVIDTGIGIPQNKHISIFDAFRQVDGSTSREYGGTGLGLTISLRFAELLGGTISLNSIEGKGSEFTLCLPITPPLSPLSAALPVLTTNISATPKTNVNTPQGKVNDDRHNLKQNDKVILLIDDDLDFGTAVIEINHRLGYKTLVANTGAEGLALTKQHHPAGILLDLGLPDKDGTDILHEIKTTHELASIPVYIISARDHDSTLNQQDIVGYLQKPVVSSQIVEAEAALIDAIKLAPAGGILLVTTMQNETNETNEILRILESRLVSEHYAVHITTPGEELQDALNNHEWGVVMIDLANLTMEKALAVAQTIRSDSHNTAMLFFGIDQLSDDEEALLRSYSDSIIVNAPQAGQRLQENIARFLRTVPSVEQTQLTSVAARSNEKKLAHKKILVIDDDPRNLFVLTSALEQQGAKVFNALNGRRAMEMLENIQVNLIITDIMMPVMDGYQTITALRANPKFAAIPIVALTAKAMQHDRENILEIGADDYLSKPVDYDVLCNMAALWCTKSVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTV0</accession>
    <name>A0A2S9GTV0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4166</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000028">
        <property type="protein sequence ID" value="PRC91165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91165">
        <property type="protein sequence ID" value="PRC91165"/>
        <property type="gene ID" value="S2091_4166"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010998">
        <property type="entry name" value="Integrase_recombinase_N"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="90" mass="10406" checksum="6E13C2EDADCF6462" modified="2018-07-18" version="1">MKNVIPNVQASDAVLKPKLLDQLKRCIRDKYYSLRTEEAYVYWARWFIRLFSQLLVTPKGGFVPSALKSRDTALSPVLRIATIHSRQTIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GU13</accession>
    <name>A0A2S9GU13_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4093</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000027">
        <property type="protein sequence ID" value="PRC91198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91198">
        <property type="protein sequence ID" value="PRC91198"/>
        <property type="gene ID" value="S2091_4093"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10600">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021866">
        <property type="entry name" value="SpoIIAA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038396">
        <property type="entry name" value="SpoIIAA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11964">
        <property type="entry name" value="SpoIIAA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SSF52091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="121" mass="13656" checksum="797542B8F3F4A36D" modified="2018-07-18" version="1">MLNYSIMTHAGILVLKPQTPLSKEDFDGLSVVVDAYLSEHLKLKGVLIHTKGFPGWENFGGFVAHMHFVSEHHKKVERVAIVTDTHFADIAESLGKHFISAEIKHFPFADDVQALKWLETF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GU29</accession>
    <name>A0A2S9GU29_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4167</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000028">
        <property type="protein sequence ID" value="PRC91166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91166">
        <property type="protein sequence ID" value="PRC91166"/>
        <property type="gene ID" value="S2091_4167"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="65" mass="7424" checksum="890AAD16C117970F" modified="2018-07-18" version="1">MDQKWQRVIDAYTAKKNAENAFQDAIESISNGVPSENFDREWLIANMAKCKSEFEAAIENNQINS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GU34</accession>
    <name>A0A2S9GU34_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Bacterial capsule synthesis protein PGA cap</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_4115</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CapA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000027">
        <property type="protein sequence ID" value="PRC91220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91220">
        <property type="protein sequence ID" value="PRC91220"/>
        <property type="gene ID" value="S2091_4115"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07381">
        <property type="entry name" value="MPP_CapA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019079">
        <property type="entry name" value="Capsule_synth_CapA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09587">
        <property type="entry name" value="PGA_cap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00854">
        <property type="entry name" value="PGA_cap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015758740" evidence="3">
        <location>
            <begin position="20"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="domain" description="PGA_cap" evidence="4">
        <location>
            <begin position="27"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="305"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="308"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC91220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="325" mass="35477" checksum="93EB1A503ABE864C" modified="2018-07-18" version="1">MIKLAVALALSIATCTAGAESNSPTVSLLFAGDIVLDGQPGKVIEQGHDPFAAFSDIINSADIRVGNLECVIATVGDPEDKNYNFRAHPRTLPILKQHFDAVSIANNHSGDFGRPAFEEMLGLLDQSGIKRFGGGHNLSEAHTPLIIERNGLRIALLGYNEFMPRSFEADEHGAGTAWSEDEQVSADIHKARDVYKADLVIPVMHWGWENEPHSSARQQQLAHLMINAGADLIIGGHPHVTEEIEYYRGKLIVYSVGNFMIDALDNAAQMRGWVMHFTLDRNGVKSWSTSVAHIDDNGIPTPALQEKSPCGTRESTQIDMCTNGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GU65</accession>
    <name>A0A2S9GU65_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_4057</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="PUGF01000026">
        <property type="protein sequence ID" value="PRC91272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91272">
        <property type="protein sequence ID" value="PRC91272"/>
        <property type="gene ID" value="S2091_4057"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="320"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="5">
        <location>
            <begin position="21"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC91272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="342" mass="38615" checksum="C3BC7706E1A673B9" modified="2018-07-18" version="1">MNPSSSFITPGMAPIKKVGRFLLYRELGRGAIGTVYFGHDPVIDRDVAIKIFHNLPSAHEKKQRDQIFMNEARAAGRLSHPNIITIFDAATDANVSFIAMEYLQGQDLRQFLADNKPLPYLIAAQMLQRIAEGLEYAHSEGVIHRDIKPANIFIQENMQAKLVDFGIARAVKRETSEGNKDQPATLFNNNILGTPNYMSPEQAQAKPVDKLTDIYSFGAVMYEMLVRQKPFQSRDMDSLIHMIVHKQIKAPHETNPEIPLVLSRIVMKAMSKQPEKRYQSAAEIALELRRYVLTEKREQKIDASKGNQSDKKTGEPYGRLFWLSCIAITIAAFVVVSSWLGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GU94</accession>
    <name>A0A2S9GU94_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RNA polymerase sigma factor RpoS</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Sigma S</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Sigma-38</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpoS</name>
        <name evidence="8" type="ORF">S2091_4064</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Interacts with the RNA polymerase core enzyme.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the sigma-70 factor family. RpoS subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000026">
        <property type="protein sequence ID" value="PRC91279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91279">
        <property type="protein sequence ID" value="PRC91279"/>
        <property type="gene ID" value="S2091_4064"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00959">
        <property type="entry name" value="Sigma70_RpoS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000943">
        <property type="entry name" value="RNA_pol_sigma70"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009042">
        <property type="entry name" value="RNA_pol_sigma70_r1_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007624">
        <property type="entry name" value="RNA_pol_sigma70_r3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007630">
        <property type="entry name" value="RNA_pol_sigma70_r4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012761">
        <property type="entry name" value="RNA_pol_sigma_RpoS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00140">
        <property type="entry name" value="Sigma70_r1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04539">
        <property type="entry name" value="Sigma70_r3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04545">
        <property type="entry name" value="Sigma70_r4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00046">
        <property type="entry name" value="SIGMA70FCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02394">
        <property type="entry name" value="rpoS_proteo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00715">
        <property type="entry name" value="SIGMA70_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="4 5" id="KW-0804">Transcription</keyword>
    <keyword evidence="1 5" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="RNA_pol_sigma70" evidence="7">
        <location>
            <begin position="123"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="5">
        <location>
            <begin position="295"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Sigma-70 factor domain-1" evidence="5">
        <location>
            <begin position="61"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Sigma-70 factor domain-2" evidence="5">
        <location>
            <begin position="99"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="232"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Sigma-70 factor domain-4" evidence="5">
        <location>
            <begin position="269"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00959"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS00715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC91279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="335" mass="37840" checksum="E85F800CE4815E9C" modified="2018-07-18" version="1">MTAKHSLLTEDELSEEASEDLREVELSDGSNDECDAAEAKEAVVEPVDELKTVLAAELSTDTTQYYLNQIGTRPLLTAPEELICATLAKKGDFVARQKMIEHNLRLVVSIAKHYINRGVALLDMIEEGNLGLMHAIDKFEPERGFRFSTYATWWIRQSIERAIMNQARTIRLPVHVVRELNQILRAKYHLEAQHHDGRDAALEDIANLVGRPMGEVQDILALSEHATSLDMPLDNDPQSSLMDMLPGESDDGPDSRAERHELSVLVRDWLSKLPDKQRVVIMRRFGLDNDDPATLETLAEEMGVTRERIRQIQQEALIKLKRSFSSRGVARDALL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUE7</accession>
    <name>A0A2S9GUE7_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 6">UTP--glucose-1-phosphate uridylyltransferase</fullName>
            <ecNumber evidence="3 6">2.7.7.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">UDP-glucose pyrophosphorylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_4005</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>alpha-D-glucose 1-phosphate + H(+) + UTP = diphosphate + UDP-alpha-D-glucose</text>
            <dbReference type="Rhea" id="RHEA:19889"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
            <dbReference type="ChEBI" id="CHEBI:58601"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="EC" id="2.7.7.9"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the UDPGP type 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.9" evidence="3 6"/>
    <dbReference type="EMBL" id="PUGF01000025">
        <property type="protein sequence ID" value="PRC91334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91334">
        <property type="protein sequence ID" value="PRC91334"/>
        <property type="gene ID" value="S2091_4005"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003983">
        <property type="term" value="F:UTP:glucose-1-phosphate uridylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006011">
        <property type="term" value="P:UDP-glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02541">
        <property type="entry name" value="UGPase_prokaryotic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005771">
        <property type="entry name" value="GalU_uridylyltTrfase_bac/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005835">
        <property type="entry name" value="NTP_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43197">
        <property type="entry name" value="PTHR43197"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00483">
        <property type="entry name" value="NTP_transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01099">
        <property type="entry name" value="galU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NTP_transferase" evidence="7">
        <location>
            <begin position="11"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00019048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC91334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="292" mass="31762" checksum="3F23F26343FD7BE7" modified="2018-07-18" version="1">MTKITKAVFPVAGLGSRFLPATKAQPKEMLTLVDKPLIQYAVEEAVAAGITELIFITGRNKRAIEDHFDTAYELEAELEASNKTALLELVQNVIPKSVSCIYIRQPAALGLGHAVLCAKPVVGDSPFMVLLADDFMLAEAGQANTTEQMVALYAQEQASIVAVQDVPREQTKQYGIVSGTPYKDRLERMSGIVEKPTPDQAPSTLAVVGRYVLDGRIFSYLEKIGKGSGGEIQLTDAIAAMLKDHPYLAYRFAATRYDCGSKLGYLKASMVLGMLHHEVGPEFTAYLQSMKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUM1</accession>
    <name>A0A2S9GUM1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_3847</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000023">
        <property type="protein sequence ID" value="PRC91432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91432">
        <property type="protein sequence ID" value="PRC91432"/>
        <property type="gene ID" value="S2091_3847"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015562">
        <property type="term" value="F:efflux transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003423">
        <property type="entry name" value="OMP_efflux"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010131">
        <property type="entry name" value="RND_efflux_OM_lipoprot_NodT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02321">
        <property type="entry name" value="OEP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01845">
        <property type="entry name" value="outer_NodT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2 5" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0564">Palmitate</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1134">Transmembrane beta strand</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015367702" evidence="2">
        <location>
            <begin position="26"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="115"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="388"/>
            <end position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU362097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC91432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="490" mass="53453" checksum="7234EEA6CCC627D6" modified="2018-07-18" version="1">MEFSLKSFRCLAQAAPLALLLSACAVGSDYVKSNVETPPAFKEQVGWKIAQPADLQIPEKWWEMYNDPVLNKLEEQVTISNQTVIQAEAQYRQARALVQAASAAYYPTVAANVSSTRTSGTSTTKDTSSAVTGPSTTDLLTANVSWEPDIWGRVRRTIEANTSSAQASAAELQAMRLSTQAQLAQDYFQLRDQDADRQLYDKTVIDYKKSLELTQHQFDFGMVLRANVVLAETLLKQTEAQAIDFDVARAQMEHAIALLVGKPASTFSIAQVDKFDTQIPVLPLGLPSALLERRPDIANAERLVAAANAQIGVSKSAYFPDLTLAATGGYQSSGLANWISLPNRIWSLGPSLAETLFDGGARKAVTDQAIAAYDASVANYRQTVLAGFREVEDNIAALRILEQEAKKQEEAVKLSRRSVELMIKQYEAGLITYLDVITVETTALSNERVYVDLLNKRLSANVLLIKALGGGWSASQLPTANAVEKPNNKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUN7</accession>
    <name>A0A2S9GUN7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">MJ0042 family finger-like domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_3911</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000024">
        <property type="protein sequence ID" value="PRC91366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91366">
        <property type="protein sequence ID" value="PRC91366"/>
        <property type="gene ID" value="S2091_3911"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021834">
        <property type="entry name" value="DUF3426"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011723">
        <property type="entry name" value="Znf/thioredoxin_put"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11906">
        <property type="entry name" value="DUF3426"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13719">
        <property type="entry name" value="zinc_ribbon_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02098">
        <property type="entry name" value="MJ0042_CXXC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="308"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="domain" description="Znf/thioredoxin_put" evidence="3">
        <location>
            <begin position="3"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="86"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC91366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="463" mass="50496" checksum="40A68A4226B93EB0" modified="2018-07-18" version="1">MLLATKCPHCRTTFKVANDQLKLQAGLVRCGVCQQVFNGIEHLAAASNTAVVAEPLKTPEPVTNPVVDKVVVIDDDDDDDEIVNAAADPVTAPTPESDPELDSDPIFEPTSESDLISISTADLDFDLPDTPPTVAVKPFLISSESGSRIEPDLDINFAPPQPQVPVPVPVPVQVPAQTHENAAEGYFKSRSKAEIEAEVQALLDADLLAELEATNSVLLNIQNLPPASSDAKKIAKVEPSFDLPESEPLSETVIPAEFLQHTDLRSHLSDTTSDDFLSQADSTADISPNSGDIAQLSFVRQANAKKRVAWLFSIGTLVLVLLLTGQATYQFRDLIAAVYPPSKATLVTLCQYARCQIQLPAQLDALSYEADELHSLPHENTYEFSLLMRNHSSLPQAWPHIELTLKDAKKQAVLRRVFTPDEYLPNPHDVSTGFPANQEQAIKLYFAVDQVKASDYVVATFYP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUP9</accession>
    <name>A0A2S9GUP9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative oxidoreductases (Related to aryl-alcohol dehydrogenases)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3854</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000023">
        <property type="protein sequence ID" value="PRC91439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91439">
        <property type="protein sequence ID" value="PRC91439"/>
        <property type="gene ID" value="S2091_3854"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NADP_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="SSF51430"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldo_ket_red" evidence="1">
        <location>
            <begin position="16"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="324" mass="34581" checksum="D3CDB6D083B0FCB6" modified="2018-07-18" version="1">MKQRQLGKTGPSSSILGLGCMGMSGMYGPAERSESIATIHAALEAGITLLDTGDFYGSGHNEILIGEALRAAPASRRDAAQISVKFGVMRDPKGGRLHYDARPAAVKNFLAYSLQRLGVDYIDIYRSARLDANVPIEETVGAIADMVKAGYVRHIGLSEVGVDTIRRAAKVHPICDLQIEYSLISRGIEESILPTCRELGIGITAYGVLSRGLIGGHWSKDMAGTGDFRSNSPRFQGENLDHNLALVDALRKVADEKHVSVAQIAIAWVAAQGEDILPLIGARRRDRLTEALGALDVVLSKTDIAMIEQAVPKGAAAGSYYAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUW3</accession>
    <name>A0A2S9GUW3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">FlaG protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3766</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000022">
        <property type="protein sequence ID" value="PRC91488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91488">
        <property type="protein sequence ID" value="PRC91488"/>
        <property type="gene ID" value="S2091_3766"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005186">
        <property type="entry name" value="FlaG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035924">
        <property type="entry name" value="FlaG-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03646">
        <property type="entry name" value="FlaG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160214">
        <property type="entry name" value="SSF160214"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="137" mass="13755" checksum="64E25E33F6AD4E45" modified="2018-07-18" version="1">MDVSILGGPAASTVQSSPGASKTPQLAPTPAPVSTPAPIPVSAAGSPHVSAPAPAPAAPTPTLAQVKQAVDNINASLNANGNSQAVQFAVDPSSKRVVVQVIDPVNGKVIRQIPSEEIIQMSMVLGQKLGKVINQEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GV00</accession>
    <name>A0A2S9GV00_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cobalamin adenosyltransferase</fullName>
            <ecNumber evidence="4">2.5.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_3678</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>AH2 + 2 ATP + 2 cob(II)alamin = A + 2 adenosylcob(III)alamin + 2 H(+) + 2 triphosphate</text>
            <dbReference type="Rhea" id="RHEA:53304"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16304"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:18036"/>
            <dbReference type="ChEBI" id="CHEBI:18408"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the Cob(I)alamin adenosyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.-" evidence="4"/>
    <dbReference type="EMBL" id="PUGF01000021">
        <property type="protein sequence ID" value="PRC91562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91562">
        <property type="protein sequence ID" value="PRC91562"/>
        <property type="gene ID" value="S2091_3678"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008817">
        <property type="term" value="F:cob(I)yrinic acid a,c-diamide adenosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009236">
        <property type="term" value="P:cobalamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016030">
        <property type="entry name" value="CblAdoTrfase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036451">
        <property type="entry name" value="CblAdoTrfase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029499">
        <property type="entry name" value="PduO-typ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12213">
        <property type="entry name" value="PTHR12213"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01923">
        <property type="entry name" value="Cob_adeno_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89028">
        <property type="entry name" value="SSF89028"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00636">
        <property type="entry name" value="PduO_Nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0169">Cobalamin biosynthesis</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Cob_adeno_trans" evidence="6">
        <location>
            <begin position="8"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU366026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC91562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="183" mass="20127" checksum="801818A5D7B5A866" modified="2018-07-18" version="1">MGNRLSKIATRTGDQGTTGLGDGSRTDKDSLRVHAMGDVDELNSQLGLLLCEDLPPGLANELLLIQHDLFDLGGEICIPGYQLITDEQVANLDALLEKYNADLPALQEFILPGGSRSASLAHVCRTVCRRAERMLVSLGKAEQINPQPRQYLNRLSDLMFVLSRVLNRYSGGGDVLWRHERTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GV06</accession>
    <name>A0A2S9GV06_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Small-conductance mechanosensitive channel</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_3821</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homoheptamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell inner membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the MscS (TC 1.A.23) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000022">
        <property type="protein sequence ID" value="PRC91543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91543">
        <property type="protein sequence ID" value="PRC91543"/>
        <property type="gene ID" value="S2091_3821"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008381">
        <property type="term" value="F:mechanosensitive ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045275">
        <property type="entry name" value="MscS_archaea/bacteria_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006685">
        <property type="entry name" value="MscS_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011066">
        <property type="entry name" value="MscS_channel_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023408">
        <property type="entry name" value="MscS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30221">
        <property type="entry name" value="PTHR30221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00924">
        <property type="entry name" value="MS_channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="SSF50182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82689">
        <property type="entry name" value="SSF82689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0407">Ion channel</keyword>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015553878" description="Small-conductance mechanosensitive channel" evidence="8">
        <location>
            <begin position="24"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="145"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="204"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="246"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="310"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="339"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU369025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC91543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="545" mass="60202" checksum="429960C10534D13E" modified="2018-07-18" version="1">MNLPKLLFCVCLVWSAAYAPVQASDMPALVTTPAPEKTNDATLTVENRAIMTFRSSVLGIEPLERVKRAESRIEKQLSNGGQHKASMLAMPPGILIQIDNAGSFYISPGDIDQFQQETLEANAKNAVDNLNLAISETHESRSLDYMLRAAAYSALATIIYFFALWLVSKVRHVVEHRLLKFANAKIDLLDDTSSQIINRERIQWVFSGLVQVFSWLLILLLSYEWLSVLMEQFPVTRPWGEHLNGYFVGLIVMLGTAILKSIPDLFTAIVIFLLARAVTQGLSRFFGRVQDKSIQLSWLDAAVAVPTRRIANMAVWLFALAMAYPYLPGANTEAFKGVSVLVGLMISMGASGLVGQVVSGLLLTYTGIYRKGEFIHVLDYEGSIVEMGMFTTRIRNGMGVELTLPNSLVLSNVTLNYSKAVQGDGFIVDTKVTIGYDTPWRQVQEMLILAAQRTPGVISHPAPKVFQTALSDFYPEYLLICQAIPCDAQLRAEVMNQLHGNIQDVFNEYGVQIMSPHYLGDPAQEKVVAKGDWFRAPAAGAVGAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GV66</accession>
    <name>A0A2S9GV66_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Phosphomethylpyrimidine synthase</fullName>
            <ecNumber evidence="10">4.1.99.17</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Hydroxymethylpyrimidine phosphate synthase</fullName>
            <shortName evidence="10">HMP-P synthase</shortName>
            <shortName evidence="10">HMP-phosphate synthase</shortName>
            <shortName evidence="10">HMPP synthase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Thiamine biosynthesis protein ThiC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">thiC</name>
        <name evidence="12" type="ORF">S2091_3720</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 10">Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>5-amino-1-(5-phospho-beta-D-ribosyl)imidazole + S-adenosyl-L-methionine = 4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine + 5'-deoxyadenosine + CO + formate + 3 H(+) + L-methionine</text>
            <dbReference type="Rhea" id="RHEA:24840"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:17245"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:58354"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:137981"/>
            <dbReference type="EC" id="4.1.99.17"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="10">Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="pathway">
        <text evidence="10">Cofactor biosynthesis; thiamine diphosphate biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the ThiC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.99.17" evidence="10"/>
    <dbReference type="EMBL" id="PUGF01000021">
        <property type="protein sequence ID" value="PRC91604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91604">
        <property type="protein sequence ID" value="PRC91604"/>
        <property type="gene ID" value="S2091_3720"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00060"/>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016830">
        <property type="term" value="F:carbon-carbon lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009228">
        <property type="term" value="P:thiamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009229">
        <property type="term" value="P:thiamine diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.540">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00089">
        <property type="entry name" value="ThiC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037509">
        <property type="entry name" value="ThiC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025747">
        <property type="entry name" value="ThiC-associated_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038521">
        <property type="entry name" value="ThiC/Bza_core_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002817">
        <property type="entry name" value="ThiC/BzaA/B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30557">
        <property type="entry name" value="PTHR30557"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13667">
        <property type="entry name" value="ThiC-associated"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01964">
        <property type="entry name" value="ThiC_Rad_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00407">
        <property type="entry name" value="phosphomethylpyrimidine_syntha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00190">
        <property type="entry name" value="thiC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 10" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="7 10" id="KW-0408">Iron</keyword>
    <keyword evidence="8 10" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="9 10" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6 10" id="KW-0784">Thiamine biosynthesis</keyword>
    <keyword evidence="5 10" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="ThiC-associated" evidence="11">
        <location>
            <begin position="21"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="10">
        <location>
            <begin position="356"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="10">
        <location>
            <begin position="397"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="242"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="271"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="300"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="336"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="436"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="440"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="463"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="504"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="584"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="587"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="592"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF13667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PRC91604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="637" mass="70939" checksum="C01743316725FE2C" modified="2018-07-18" version="1">MNANPKFLSATATVDAAAIAPLPNSRKIYVQGSRPDIQVPMREISQSDTPASFGFEQNPPIYVYDTSGPYTDPNATIDIRSGLAAVRANWIAERNDTDELSGPSSAYGVERLHDPKCAELRFNLTRLPRRAKAGKNVSQMHYARQGIITPEMEYVAIRENMQRKEYLEKLRQSGVMGNKLADLMGRQHPGQNFGTAMPAEITPEFVREEIARGRAIIPANINHPEVEPMIIGRNFLVKINANIGNSAVTSSIGEEVEKMTWAIRWGGDNVMDLSTGKHIHETREWIIRNSPVPIGTVPIYQALEKVNGKAEDLTWEIFRDTLIEQAEQGVDYFTIHAGVRLQYVPMTAKRLTGIVSRGGSIMAKWCLAHHEESFLYTHFEEICQIMKAYDVSFSLGDGLRPGSIFDANDEAQLAELKTLGELTQIAWQHDVQVMIEGPGHVPLHLIKENMDLQLEQCFEAPFYTLGPLTTDIAPGYDHITSGIGAATIGWYGTAMLCYVTPKEHLGLPNKADVKDGIITYKIAAHVADLAKGHPGAQIRDNALSKARFEFRWDDQFNLGLDPDKAREFHDETLPKDSAKVAHFCSMCGPHFCSMKITQEVREYAAKQGISEIAALKKGMEVKSVEFIKSGAEIYRKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVD9</accession>
    <name>A0A2S9GVD9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Proton-translocating NADH-quinone oxidoreductase, chain L</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">S2091_3625</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Membrane</location>
            <topology evidence="1 5">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000020">
        <property type="protein sequence ID" value="PRC91687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91687">
        <property type="protein sequence ID" value="PRC91687"/>
        <property type="gene ID" value="S2091_3625"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008137">
        <property type="term" value="F:NADH dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042773">
        <property type="term" value="P:ATP synthesis coupled electron transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018393">
        <property type="entry name" value="NADHpl_OxRdtase_5_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001750">
        <property type="entry name" value="ND/Mrp_mem"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003945">
        <property type="entry name" value="NU5C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001516">
        <property type="entry name" value="Proton_antipo_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42829">
        <property type="entry name" value="PTHR42829"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00361">
        <property type="entry name" value="Proton_antipo_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00662">
        <property type="entry name" value="Proton_antipo_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01974">
        <property type="entry name" value="NDH_I_L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="45"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="94"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="126"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="149"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="181"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="221"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="264"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="294"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="322"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="346"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="389"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="423"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="501"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="568"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="666"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="domain" description="Proton_antipo_N" evidence="9">
        <location>
            <begin position="77"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="domain" description="Proton_antipo_M" evidence="8">
        <location>
            <begin position="143"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="465"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="465"/>
            <end position="493"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC91687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="691" mass="75490" checksum="082634A33837ECEB" modified="2018-07-18" version="1">MTVGQINPQLLLAVPLAPLAGAAIAGLLGTKFLGNIVGRKTSHSVTILGVLIAMIISIYTLMAVLDGASFNGTIYQWMDVAGLKLEVGFQIDSLSAMMMCVVTFVSLMVHIYTIGYMAEDEGYNRFFSYISLFTFSMLMLVMSNNFLQLFFGWEAVGLVSYLLIGFWYTKPTAIFANMKAFLVNRVGDFGFILGIGLIVAYTNSMNYSEVFANKDILLHGVLPGTDWMLVTVACICLFIGAMGKSAQFPLHVWLPDSMEGPTPISALIHAATMVTAGIFMVARMSPLFELSDTALSFILVIGAITALFMGFMGIIQNDIKRVVAYSTLSQLGYMTVALGASAYSVAVFHLMTHAFFKALLFLGAGSVIMGMHHDQDIRNMGGLRKYMKITWITSLVGSLALIGTPFFSGFYSKDSIIEAVQSSHLAGAGFAQFSVLAGVFVTAFYSFRMYFLVFHGKENFGKAHAEHGHDDHHAADAHADDHDAHEHHGLAPGQKPHESPWVITLPLILLAIPSALIGYFTIEPMLHGSFFKDAIFVAGQHEAMQTLTEEFHEVGGALGMAIHSLTSLPFWLAVAGVATSYLFYMVKPEIPAALKKNLSFIYTLLDNKYYMDKFNDVVFAGGARLLGGGLWNIGDKGLIDGLIVNGSAKLVAWSSRAIRTIQTGYIYHYAFVMILGVLGFLIYFMPNPFTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVR4</accession>
    <name>A0A2S9GVR4_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cyanate hydratase</fullName>
            <shortName evidence="3">Cyanase</shortName>
            <ecNumber evidence="3">4.2.1.104</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Cyanate hydrolase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Cyanate lyase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">cynS</name>
        <name evidence="5" type="ORF">S2091_3543</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 3">Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>cyanate + 3 H(+) + hydrogencarbonate = 2 CO2 + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:11120"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29195"/>
            <dbReference type="EC" id="4.2.1.104"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the cyanase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.104" evidence="3"/>
    <dbReference type="EMBL" id="PUGF01000019">
        <property type="protein sequence ID" value="PRC91788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91788">
        <property type="protein sequence ID" value="PRC91788"/>
        <property type="gene ID" value="S2091_3543"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008824">
        <property type="term" value="F:cyanate hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009439">
        <property type="term" value="P:cyanate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00559">
        <property type="entry name" value="Cyanase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00535">
        <property type="entry name" value="Cyanate_hydrat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008076">
        <property type="entry name" value="Cyanase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003712">
        <property type="entry name" value="Cyanate_lyase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036581">
        <property type="entry name" value="Cyanate_lyase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34186">
        <property type="entry name" value="PTHR34186"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02560">
        <property type="entry name" value="Cyanate_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001263">
        <property type="entry name" value="Cyanate_hydratas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01693">
        <property type="entry name" value="CYANASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01116">
        <property type="entry name" value="Cyanate_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55234">
        <property type="entry name" value="SSF55234"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00673">
        <property type="entry name" value="cynS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyanate_lyase" evidence="4">
        <location>
            <begin position="83"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="96"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="99"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM01116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC91788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="156" mass="16946" checksum="4CAA993F65C3367B" modified="2018-07-18" version="1">MQQSHAYQDSRLALTANVIAAKALKDLSWEQLSADTGLSIAYVTAALLGQHSLPKAAAELVCERLGLGAESARELQMIPLRGSIANGIPTDPTIYRFYEMIQIYGTTLKALVHEKFGDGIISAINFKLDIKKIDDPEGGSRAVITLDGKFLPNKPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVU2</accession>
    <name>A0A2S9GVU2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_3390</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000018">
        <property type="protein sequence ID" value="PRC91834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91834">
        <property type="protein sequence ID" value="PRC91834"/>
        <property type="gene ID" value="S2091_3390"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="326"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="188"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="600"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="285"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC91834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="629" mass="70356" checksum="6548DE8C7A23D042" modified="2018-07-18" version="1">MFLSLKDTGIVINNARQLLLFILNLLSRRTAGALIIPIKRHLLWKFIILTCLSLCVQSVFAINFGDAALRSNLGQGLHVQVPISGAPDDVLVASCFKIKLETLEGDFIAIPHIEFAEPNRADTATLINLSTKELMIEPAVKLSIALTCGASLQREYSLLFDYAELSVAAPVVATAAAVGVASEEPIASNTTAPETKPATAKRVPRTPVTTPRKIVIKNTAAKINTSSSGKDALRVSNEELLPDFASTSPAKLAAQPSGNMEQQRNQENNLATIRLATMLRDESALLETQKEMQDEQKKIQKLEAEIQQLKLQIQKKPQQEQVAPTLLIKLIALVVLLLLSLIGMGLFIAYKARQNRNKIWWDPSAENKKNVEEIVDSLQSSAEEGDLDPSQIIKAPETKPHSATPSEEEINYAQYRTDLSPQYKRKGLPTLEETDSTSFNIFTNRRGQSIQIEEISDITQEAEFWMSVNDPNRAIEILEPQSLDENPSMPITWLYLLDLYQLVGNEKKYSELRIRFKHKFNTNIPHFGEVIDPNNSRNLEDFPHLTSKCCAFWNTNYILPFLESLLVDDRDGERVGFDLPVYRDILLLISICIELERTKKPPSSSTLSKEPKNLQPVLEIKETPIPDKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVV6</accession>
    <name>A0A2S9GVV6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nucleoside-diphosphate-sugar epimerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3396</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000018">
        <property type="protein sequence ID" value="PRC91840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91840">
        <property type="protein sequence ID" value="PRC91840"/>
        <property type="gene ID" value="S2091_3396"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="1">
        <location>
            <begin position="4"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="347" mass="37434" checksum="EAC0B6E50C0798C7" modified="2018-07-18" version="1">MATVLVTGAGGYLASWIVNCLLQDGHVVHGTVRKIQDTQKVAHLLQLADGYPDRLKLFDADLLIAGSFDVAMEGCSIVIHAASPYFIGTPKDPMAELVNPAVKGTRNVLDAVNRTGCVQRVVLTSSIAAMYGNVVDLKDADATMLQEGDINHSSSIASNPYAYSKTLAEKAAWEIHGQQSRWSLVTINPGAIFGPSLSKRKDATSVTMIIQFLNGSFRSGVPNLRLGVVDVRDAAIAHVKAATLASASGRYIAVAESLTLLEIARKIAGSNPAFISKLPAKEVPKALIWLIAPLIGMTREYVAKNVSYPINFNNRRSREELSVIYRPSLTTLNDHVKQLVDDGLLED</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVV9</accession>
    <name>A0A2S9GVV9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3415</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000018">
        <property type="protein sequence ID" value="PRC91859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91859">
        <property type="protein sequence ID" value="PRC91859"/>
        <property type="gene ID" value="S2091_3415"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021455">
        <property type="entry name" value="DUF3106"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11304">
        <property type="entry name" value="DUF3106"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="98"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="150"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="237" mass="26119" checksum="B68604E66D228B5E" modified="2018-07-18" version="1">MGKTSLQKLIPLWPLRYCLIPSLLGAFLLIAPLKGHAVDPVKAVPQAPVQAIGNGSWGTLTPVQKQILAPLVNEWNKFTPDRKQKWLVFSEKFQKMKPEEQKRAQEKMQQWEKLTPEQRVAARENYIRSNKLQPDQRTQKWQEYQQLTDAQKAQLATHPEKKKLITNLPTPEESKVKKLQPLKTPHKPVSTAPAASAPSKAAAAVAPNATPAVAPAAAVPPVTALPTASQPAASTSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVY8</accession>
    <name>A0A2S9GVY8_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">tRNA(Ile)-lysidine synthase</fullName>
            <ecNumber evidence="7">6.3.4.19</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">tRNA(Ile)-2-lysyl-cytidine synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">tRNA(Ile)-lysidine synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">tilS</name>
        <name evidence="9" type="ORF">S2091_3439</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>ATP + cytidine(34) in tRNA(Ile2) + L-lysine = AMP + diphosphate + H(+) + lysidine(34) in tRNA(Ile2)</text>
            <dbReference type="Rhea" id="RHEA:43744"/>
            <dbReference type="Rhea" id="RHEA-COMP:10625"/>
            <dbReference type="Rhea" id="RHEA-COMP:10670"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32551"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:82748"/>
            <dbReference type="ChEBI" id="CHEBI:83665"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.4.19"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="7">The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the tRNA(Ile)-lysidine synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.19" evidence="7"/>
    <dbReference type="EMBL" id="PUGF01000018">
        <property type="protein sequence ID" value="PRC91883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91883">
        <property type="protein sequence ID" value="PRC91883"/>
        <property type="gene ID" value="S2091_3439"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016879">
        <property type="term" value="F:ligase activity, forming carbon-nitrogen bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01992">
        <property type="entry name" value="PP-ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01161">
        <property type="entry name" value="tRNA_Ile_lys_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012796">
        <property type="entry name" value="Lysidine-tRNA-synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011063">
        <property type="entry name" value="TilS/TtcA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012094">
        <property type="entry name" value="tRNA_Ile_lys_synt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012795">
        <property type="entry name" value="tRNA_Ile_lys_synt_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015262">
        <property type="entry name" value="tRNA_Ile_lys_synt_subst-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43033">
        <property type="entry name" value="PTHR43033"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01171">
        <property type="entry name" value="ATP_bind_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09179">
        <property type="entry name" value="TilS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11734">
        <property type="entry name" value="TilS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00977">
        <property type="entry name" value="TilS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02433">
        <property type="entry name" value="lysidine_TilS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02432">
        <property type="entry name" value="lysidine_TilS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 7" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="TilS_C" evidence="8">
        <location>
            <begin position="380"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="29"/>
            <end position="34"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC91883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="455" mass="51126" checksum="CFC73596100F357F" modified="2018-07-18" version="1">MQARFELALRSILADVPSQSDLRVAVAYSGGLDSAVLLQLCAAYTKQNPIQLMAFHVHHGLSPNADAWVTHCQQQCIALDVPFEVAHVQLGRTNDEGVEAAARKKRYAALGELCERHHVDIILTAHHQDDQAETMLLQLLRGAGVAGLCGMQQCHRAPGLLANTSVLLARPLLDCTRAELEDYAVQQHVQHVEDESNSDARYTRNALRHQIMPLLAQHFPAYQARFARTAQHAQSALYLLEQLAEQDYAHCLSSFGAANLDVLQLQQLPEARIDNVLRHWIALHHEQMPSTARLAEIRKQLLHARDDAQVSVKHGDIEVHRYRQQLSIATCAKPTPYVQNFKWQGETSIAFPAFSGVMHFDSVLPDQPGIDRTWLLAQQLEMRPRQGGERLKLAVNRPTRSMKSHYQTSGIPYWQRERLPFIFVGTELLFAAGIGVHGDFQVTEAECVTLRWQAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWA2</accession>
    <name>A0A2S9GWA2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3323</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000017">
        <property type="protein sequence ID" value="PRC91981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91981">
        <property type="protein sequence ID" value="PRC91981"/>
        <property type="gene ID" value="S2091_3323"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="63" mass="7408" checksum="20F457126868C220" modified="2018-07-18" version="1">MHLQTGDEIGFELGKLVNHAEMRPQQEFDENNRNGISADALALQPSCRRKFLHFRARRFYLFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWA4</accession>
    <name>A0A2S9GWA4_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Aldehyde dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">S2091_3349</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3 7">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000017">
        <property type="protein sequence ID" value="PRC92007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92007">
        <property type="protein sequence ID" value="PRC92007"/>
        <property type="gene ID" value="S2091_3349"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016620">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006081">
        <property type="term" value="P:cellular aldehyde metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012394">
        <property type="entry name" value="Aldehyde_DH_NAD(P)"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43570">
        <property type="entry name" value="PTHR43570"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036492">
        <property type="entry name" value="ALDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
        <property type="entry name" value="ALDEHYDE_DEHYDR_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 3 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="105"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="domain" description="Aldedh" evidence="9">
        <location>
            <begin position="37"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="active site" evidence="4 5">
        <location>
            <position position="225"/>
        </location>
    </feature>
    <feature type="active site" evidence="4 6">
        <location>
            <position position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR036492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR036492-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC92007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="482" mass="53763" checksum="30A7BEA47FD9A94A" modified="2018-07-18" version="1">MNAPIDTHLSPAIPVEFTECFQRQRAAYFADPVPSYASRRADLENLALMLKENKDALIAAINADYGNRSTFETLFAEFFVVLQEIKDNLKHLKKWMRPQKRKIDLILYPTSSVAVIPQPLGVIGVIVPWNFPLNLSFAPLAAIFGAGNRAMLKMSENSANLARLLIEITPKYFPPEKLQFFEDGGGRGPAFSSLPFDHLFFTGSGQTGRAVMASAARNLTPVTLELGGKSPAVVGPDFPIATAADRIMWVKAFNAGQICTNVDYVYLPAGCEEVFAAEAKRVVTERYPDINHNDYTSIIDQRSYDRLQATLDDAIAKGARVVNLFEDCKPDANQRKFPLTLVFNVTDEMEIMQREIFGPLLPIKTYQYAQEVVDYVNAHDRPLAFYPFTHDKALQDFYITRVMSGGVSVNTALLHVAQHDIPFGGVGASGMGHYHGLEGFTTFSKMRPVFYQGRFSAIKLMMLPPYEKSANKVINMLIKFFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWI9</accession>
    <name>A0A2S9GWI9_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Transcription termination factor Rho</fullName>
            <ecNumber evidence="8">3.6.4.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">ATP-dependent helicase Rho</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">rho</name>
        <name evidence="11" type="ORF">S2091_3232</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homohexamer. The homohexamer assembles into an open ring structure.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8 9">Belongs to the Rho family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.-" evidence="8"/>
    <dbReference type="EMBL" id="PUGF01000016">
        <property type="protein sequence ID" value="PRC92097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92097">
        <property type="protein sequence ID" value="PRC92097"/>
        <property type="gene ID" value="S2091_3232"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008186">
        <property type="term" value="F:ATP-dependent activity, acting on RNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006353">
        <property type="term" value="P:DNA-templated transcription, termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04459">
        <property type="entry name" value="Rho_CSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01128">
        <property type="entry name" value="rho_factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01884">
        <property type="entry name" value="Rho"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000194">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_nucl-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011129">
        <property type="entry name" value="CSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041703">
        <property type="entry name" value="Rho_factor_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011112">
        <property type="entry name" value="Rho_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036269">
        <property type="entry name" value="Rho_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011113">
        <property type="entry name" value="Rho_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004665">
        <property type="entry name" value="Term_rho"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46425">
        <property type="entry name" value="PTHR46425"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00006">
        <property type="entry name" value="ATP-synt_ab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07498">
        <property type="entry name" value="Rho_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07497">
        <property type="entry name" value="Rho_RNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00357">
        <property type="entry name" value="CSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00959">
        <property type="entry name" value="Rho_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF68912">
        <property type="entry name" value="SSF68912"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00767">
        <property type="entry name" value="rho"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51856">
        <property type="entry name" value="RHO_RNA_BD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 8" id="KW-0347">Helicase</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="7 8" id="KW-0804">Transcription</keyword>
    <keyword evidence="6 8" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="1 8" id="KW-0806">Transcription termination</keyword>
    <feature type="domain" description="Rho RNA-BD" evidence="10">
        <location>
            <begin position="48"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="169"/>
            <end position="174"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="181"/>
            <end position="186"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="212"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC92097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="418" mass="46935" checksum="AAEE80F95C25952E" modified="2018-07-18" version="1">MHLSELKALHVSALLEMAIGLDIDNAARMRKQELMFAILKKRAKQGEQIFGDGALEVLPDGFGFLRSPDASYMASTDDIYISPSQIRRFNLHTGDSIEGEVRTPKDGERYFALVKVDKVNGESPEASKHRILFENLTPLHPNKPLLLERDMRGEENTTGRIIDLIAPIGKGQRGLLVASPKSGKSVMLQHIAHAITANHPDITLIVLLIDERPEEVTEMQRSVRGEVVASTFDEPATRHVQVAEMVLEKAKRLVEMKKDVVILLDSITRLARAYNTVIPASGKVLTGGVDANALQRPKRFFGAARNVEEGGSLTIIATALIETGSRMDDVIFEEFKGTGNMEVHLERRLAEKRTYPAINLNKSGTRREELLIKPDQLQKIWVLRKLLYSMDEIEAMEFILDKMKGTKNNAEFFEMMRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWL3</accession>
    <name>A0A2S9GWL3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycine/D-amino acid oxidases (Deaminating)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3248</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000016">
        <property type="protein sequence ID" value="PRC92113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92113">
        <property type="protein sequence ID" value="PRC92113"/>
        <property type="gene ID" value="S2091_3248"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DAO" evidence="1">
        <location>
            <begin position="2"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="424" mass="46213" checksum="1D7EBF3AC617D79F" modified="2018-07-18" version="1">MKVIVLGAGIIGTASAWFLHKAGHEVCVIDRQPGAAQETSFANGCQISVSHSEPWANPSALLKILKSLGQEDAPLLYRFRADWLQWKWALSFLRECAPGRAAQNIRPIVALCEYSRRTLQDVRVDTGINYDCLNKGILHFYTDQKEFDASLPAAQLMRELGCPRESINAAEVLRMEPALASSSKKIVGGDFTANDESGDVFKFTTGLAQKAAEAGVNFQFNTQITRLITEGTGQARKVIGVEIIHPDGHHAVLYADAFVVAMGSFSVPILEPLGINLMLYPGKGYSATYAIKNPDAAPTISLIDDGFKLVTSRLGDRLRVAGTCELNGYTRDLNDTRCAALTRRTRELFPDACDYENPIYWAGLRPLTPSNVPYIGKTKISNLFLNTGHGTLGWTMGCGSGQAIADIVSGRLPDVDFTFTGFTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GX06</accession>
    <name>A0A2S9GX06_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2914</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92255">
        <property type="protein sequence ID" value="PRC92255"/>
        <property type="gene ID" value="S2091_2914"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="88"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="112"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="138"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="168"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="195" mass="21352" checksum="899CF8F794712308" modified="2018-07-18" version="1">MNKIETNPVVASAHVGRAFGAMIFSIFGAVWLAAWSLQALPNNYFPLGLIAICALLIFTLAYRRYQQYLPESKALAESPARKRIMRQFNIINAAQWVAILIIVNVLNNMGLSSWAIPTAIFIIGLHFLPLTHIFRNPAHYVTGMAMLLLAVFYPLLMVNGGNNPAGCLGAGLILWVSAVWAVTANSTIAQVRSVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GX39</accession>
    <name>A0A2S9GX39_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Outer membrane autotransporter barrel domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3142</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92226">
        <property type="protein sequence ID" value="PRC92226"/>
        <property type="gene ID" value="S2091_3142"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006315">
        <property type="entry name" value="OM_autotransptr_brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011250">
        <property type="entry name" value="OMP/PagP_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005618">
        <property type="entry name" value="OMPW"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36920">
        <property type="entry name" value="PTHR36920"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03922">
        <property type="entry name" value="OmpW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56925">
        <property type="entry name" value="SSF56925"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01414">
        <property type="entry name" value="autotrans_barl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015703466" evidence="2">
        <location>
            <begin position="23"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="203" mass="22301" checksum="451258110DAB9D9A" modified="2018-07-18" version="1">MKKISLVIALAVIGFNSASVMAQESPWLVRARIVDVDTANKSDPIAGVGASNQITVSNKVIPEFDISYFFTPNWATELVLTYPQKHDVYLSGAQIGTVKELPPTLTVQYHFTPESQFSPYLGAGINYTNFSSVELANGAISLDNHSFGLALQAGIDYKLDKNWSLNMDVKYVQMRSDVYLGGSQISNIKIDPWLIGVGVGYRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXA0</accession>
    <name>A0A2S9GXA0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Virulence-associated protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3006</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92347">
        <property type="protein sequence ID" value="PRC92347"/>
        <property type="gene ID" value="S2091_3006"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007159">
        <property type="entry name" value="SpoVT-AbrB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037914">
        <property type="entry name" value="SpoVT-AbrB_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00966">
        <property type="entry name" value="SpoVT_AbrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89447">
        <property type="entry name" value="SSF89447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SpoVT-AbrB" evidence="1">
        <location>
            <begin position="7"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="78" mass="9206" checksum="E4DD80C18F432985" modified="2018-07-18" version="1">MHLTKIFRNGNSQAVRVPAELAYERTDIELEIERIGDELRIRPARRSLTGVLQKFARFESDFMINGREEQEQSEREDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXB5</accession>
    <name>A0A2S9GXB5_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">2-dehydro-3-deoxyphosphooctonate aldolase</fullName>
            <ecNumber evidence="6">2.5.1.55</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">3-deoxy-D-manno-octulosonic acid 8-phosphate synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">KDO-8-phosphate synthase</fullName>
            <shortName evidence="6">KDO 8-P synthase</shortName>
            <shortName evidence="6">KDOPS</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Phospho-2-dehydro-3-deoxyoctonate aldolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">kdsA</name>
        <name evidence="8" type="ORF">S2091_3010</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>D-arabinose 5-phosphate + H2O + phosphoenolpyruvate = 3-deoxy-alpha-D-manno-2-octulosonate-8-phosphate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:14053"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57693"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:85985"/>
            <dbReference type="EC" id="2.5.1.55"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Bacterial outer membrane biogenesis; lipopolysaccharide biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4 6">Carbohydrate biosynthesis; 3-deoxy-D-manno-octulosonate biosynthesis; 3-deoxy-D-manno-octulosonate from D-ribulose 5-phosphate: step 2/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the KdsA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.55" evidence="6"/>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92351">
        <property type="protein sequence ID" value="PRC92351"/>
        <property type="gene ID" value="S2091_3010"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00030"/>
    <dbReference type="UniPathway" id="UPA00357">
        <property type="reaction ID" value="UER00474"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008676">
        <property type="term" value="F:3-deoxy-8-phosphooctulonate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019294">
        <property type="term" value="P:keto-3-deoxy-D-manno-octulosonic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00056">
        <property type="entry name" value="KDO8P_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006218">
        <property type="entry name" value="DAHP1/KDSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006269">
        <property type="entry name" value="KDO8P_synthase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21057">
        <property type="entry name" value="PTHR21057"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00793">
        <property type="entry name" value="DAHP_synth_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01362">
        <property type="entry name" value="KDO8P_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0448">Lipopolysaccharide biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DAHP_synth_1" evidence="7">
        <location>
            <begin position="7"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC92351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="283" mass="30330" checksum="AF40B909005E0AD4" modified="2018-07-18" version="1">MKLCGFEIGLNHPLFLIAGPCVIESRQMAMDTAGYLKEITTELNIPFIYKSSFDKANRSSGSSFRGLGIDKGLEILADVKRELNVSVLTDVHSIDEIAAVAAVVDVLQTPAFLCRQTDFIEACAVSGKPVNFKKGQFLAPHDMQHVINKARAAALAQGLPDQFMACERGASFGYNNLVSDMRSLAIMRETGCPIVFDATHSVQLPGGQGTTSGGQREFVPVLARAAVAVGISGLFMETHPNPAEAKSDGPNAVPLSRMKELLTTLTALDQIVKAQGFLESNFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXN1</accession>
    <name>A0A2S9GXN1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2848</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92473">
        <property type="protein sequence ID" value="PRC92473"/>
        <property type="gene ID" value="S2091_2848"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="61" mass="7041" checksum="7BA7F285DC2582A0" modified="2018-07-18" version="1">MLIKNSIALDSFIFDCADFIEEVTIHLQDESNNAMVVSILFLYPSFLKGWRNDQSCKRGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXN4</accession>
    <name>A0A2S9GXN4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2862</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92487">
        <property type="protein sequence ID" value="PRC92487"/>
        <property type="gene ID" value="S2091_2862"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="186" mass="20699" checksum="8E1AD0F2C821CE99" modified="2018-07-18" version="1">MFDATEQILSLEGYAAWNEEYLCKLCECSRGALRYQFPDGRYDLLPSFIEAVIEQDSKMVESLGDLTPVERMYLFLMSMRFKPPSQATRAILEISMAARGDAKLLSRIEPIMESANARVLGMAAGETDPEILALRCLLHGASMYSLHKDFTPLGLNQSLGWILDLLPIPPALAARVAEMVKARQVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXP8</accession>
    <name>A0A2S9GXP8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cytochrome c peroxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_2864</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="SMR" id="A0A2S9GXP8"/>
    <dbReference type="EnsemblBacteria" id="PRC92489">
        <property type="protein sequence ID" value="PRC92489"/>
        <property type="gene ID" value="S2091_2864"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004852">
        <property type="entry name" value="Di-haem_cyt_c_peroxidsae"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03150">
        <property type="entry name" value="CCP_MauG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0349">Heme</keyword>
    <keyword evidence="3 4" id="KW-0408">Iron</keyword>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cytochrome c" evidence="5">
        <location>
            <begin position="63"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="5">
        <location>
            <begin position="250"/>
            <end position="427"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC92489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="429" mass="46933" checksum="9791FC87AE3A273F" modified="2018-07-18" version="1">MINFLKAETSPISPWSRSAIVFACVTLALAACQPSTDQEKSKLINHRSVTAQDAQASSSGLSELALLGKKLFFDPALSGSGKMSCATCHDPANAYGPPNNLAVQLGGADLKTQGLRAVPSLRYVLNRTPFWSKQFVSNPVERLIETDSPPVGGLTWDGRFNTLHEQASAPLLAANEMANESPNSVISKVAKSAYATDFAHAFGQNVWQDPARAFNGLLLAIERFELEDASFHPYTSKFDQTLKGQATLSASELKGLQLFSAPDKGNCASCHLAVSGADHSAPLFTDFSFSALGAPRNPQIIANRNRQFYDLGLCGPSRIDQQKKHEYCGMFKTPGLRNVANRRVFMHNGVFNDLESVVRFYVERDTKPEKWYPKNSDGSVNKFNDLPVNLRSNVDTLDVPLNRKKSDSPALSDEEIKDVVAFLKTLSDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GY37</accession>
    <name>A0A2S9GY37_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">RecT family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2687</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92632">
        <property type="protein sequence ID" value="PRC92632"/>
        <property type="gene ID" value="S2091_2687"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006259">
        <property type="term" value="P:DNA metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018330">
        <property type="entry name" value="RecT_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03837">
        <property type="entry name" value="RecT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="323" mass="35517" checksum="92013110A8F7633C" modified="2018-07-18" version="1">MNEITEVVNQESDLNIVPSSSGALILDAASMDSMYRMAEIMAKGKSTIPDHLKGNVGDCMAIVMQSIQWKMNPFAVAQKTHTVNGILGYEGQLVNAVIQSSGVTESRFAYEWFGDWAKIIGKTKVIDMPAKDGKKAYQFRVPNSTLEDELGLGIRVSAILKGEIEPRVLELLLVQASVRNSPLWASDPKQQLAYLAVKRWARLFSPDVILGVYTPDEFDTSPQKPQSRNMGTADVVEPNVDMPTLLASAQATKTDDEALNFWKANNQLLIKHPTHHAEFKKVIAEHRTDLAAKEAKRTIDNTATQGSASFVDAMNNAESKEAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYE7</accession>
    <name>A0A2S9GYE7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HD domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2450</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92720">
        <property type="protein sequence ID" value="PRC92720"/>
        <property type="gene ID" value="S2091_2450"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008081">
        <property type="term" value="F:phosphoric diester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037522">
        <property type="entry name" value="HD_GYP_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01590">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01966">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51832">
        <property type="entry name" value="HD_GYP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HD-GYP" evidence="1">
        <location>
            <begin position="331"/>
            <end position="544"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="561" mass="63641" checksum="2615C37913F117D2" modified="2018-07-18" version="1">MRFTVVRSLLISSIYMTHESNDYQTPSIEQRLEQLTELCVELSSNHDTPLLTEHILRVAQRMSNADGGTLYRVSKDGKNLHFNISINDSLGMYQGGVRGQAIEMADLPLLDINGQANLNTVAAYAANMRCSVNIPDIYQADGFSFTGMLQFDQQQKYRTVSLLTVPMLDHENELIGVLQLINAINPQTKIISTFSDTDQRFIEALASQAAIALTNQLLISQLENLFESLIKLINIGIDEKSPHTGKHCMHVPELTMMLADAVHLTDSGPLADFKMSVRDRKELWMAGLLHDCGKITTPTHVVEKSTKLEMIYDRIHAIDCRFEVLKRDAEICILKQKLANADLTVQQQLDQALQQELIQLEQDRDFLRHANIGGERMSMEDQERVKQIANYQWCGADNVMGNFLDQEEVDNLTIRAGTLNPQERSIINNHIVLTIKMLEALPWPRHLQNVPEYAGGHHERMDGKGYPRGLRGEQMSVQARLMAIADIFEALTAKDRPYKTGKMLTESLDILGRFCLNGHIDPAIFDVFVRRKVYLDYAKRFMDPEQLDEVDENKIPGYMVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYH1</accession>
    <name>A0A2S9GYH1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">PhnS2: putative 2-aminoethylphosphonate ABC transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_2502</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92772">
        <property type="protein sequence ID" value="PRC92772"/>
        <property type="gene ID" value="S2091_2502"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017663">
        <property type="entry name" value="ABC_PhnS2_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026045">
        <property type="entry name" value="Ferric-bd"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002825">
        <property type="entry name" value="CfbpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03261">
        <property type="entry name" value="phnS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015611082" evidence="3">
        <location>
            <begin position="24"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="226"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR002825-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC92772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="342" mass="37779" checksum="4C94F4F6DC58C950" modified="2018-07-18" version="1">MQIRHSFMTIALLLATFSRVASAESNLTVYTALEADQLKAYQSQFETEYPDIKIRWVRDSTGVITAKLLAEKAAPQADVVMGVAATSLLVLQKEGMLQAYAPKGVEKLSKQYVDNRNPPSWVGMDVWGAAICFNTVEANKLGLKKPESWKDLLKPEYKGKIVMPNPASSGTGYFDVSAWLLQFGDKGGWDYMDKLHENIAQYTHSGSKPCKQAASGEFPIGIAFEYRGAKLKESGAPIELVFPKEGLGWDVEATAIMAGTKNLDAARKLADWSASKSGNEQFAKNFAIVAYPGVAKANPLIPANYEDMLIKQDLNWSALNRDRILAEWTKRYDGKSEPKPKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYN3</accession>
    <name>A0A2S9GYN3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Lipid A export permease/ATP-binding protein MsbA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">S2091_2540</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92810">
        <property type="protein sequence ID" value="PRC92810"/>
        <property type="gene ID" value="S2091_2540"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034040">
        <property type="term" value="F:ATPase-coupled lipid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011917">
        <property type="entry name" value="ABC_transpr_lipidA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="PTHR24221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="SSF90123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02203">
        <property type="entry name" value="MsbA_lipidA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 9 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-1278">Translocase</keyword>
    <keyword evidence="2 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="62"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="140"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="162"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="12">
        <location>
            <begin position="23"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="340"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="374"/>
            <end position="381"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PRC92810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="584" mass="64631" checksum="12DFA365C49659A7" modified="2018-07-18" version="1">MNINPYYTRLANAVKPYKKRIGLALLGMIGAACTEPIFPYILKVLTDNGFSEERSMPIWQVPIALVGIFLFRGMFTFCTQYYMAWVANKLLSDLRDAMFKRTLNVSIAYYLNESSGRLINTIMSEVQQVVEMVKVSINTLIRDSITVIVLMVFLIYQNWQLTLVALLIIPSMAYVVRITSKRLRHLNQHQQNLNSELTQVVEEATRASQVIRIFGGQKYEHRRFRFKSEKLRGYAQRVTVVSGSTTPLTQMVAALAVSIVIVVAMRPSLLPFHSHQFTSGDFVQYITAMLLLLAPLKRLSDLNGPLQRGLIASESVFNLIDTPIEPEGGIDLDGRAKGNLEFVNTEFSYAGQEQRALKGINLRVNAGETVALVGMSGGGKTSLVNLVPRFYTPTAGSIKLDGHDLADISLTSLRSQIAMVGQNVVLFDDTIAANIAYGDENPDQARIEAAVKAAHLTDVIENLPLGLQTEIGDNGTRLSGGQRQRLAIARAIYKNAPILILDEATSALDSESERAVQAALDSLIQGRTTLVIAHRLSTIERADRIVVLTGGEITEIGTHTELLQKNGTYAHLHQLQFTKELEVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYV1</accession>
    <name>A0A2S9GYV1_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">DNA topoisomerase 4 subunit B</fullName>
            <ecNumber evidence="6">5.6.2.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Topoisomerase IV subunit B</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">parE</name>
        <name evidence="8" type="ORF">S2091_2321</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>ATP-dependent breakage, passage and rejoining of double-stranded DNA.</text>
            <dbReference type="EC" id="5.6.2.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="6">Heterotetramer composed of ParC and ParE.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the type II topoisomerase GyrB family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the type II topoisomerase family. ParE type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.2" evidence="6"/>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92904">
        <property type="protein sequence ID" value="PRC92904"/>
        <property type="gene ID" value="S2091_2321"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003918">
        <property type="term" value="F:DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006265">
        <property type="term" value="P:DNA topological change"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.670">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00938">
        <property type="entry name" value="ParE_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002288">
        <property type="entry name" value="DNA_gyrase_B_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001241">
        <property type="entry name" value="Topo_IIA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013760">
        <property type="entry name" value="Topo_IIA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013759">
        <property type="entry name" value="Topo_IIA_B_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013506">
        <property type="entry name" value="Topo_IIA_bsu_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018522">
        <property type="entry name" value="TopoIIA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005737">
        <property type="entry name" value="TopoIV_B_Gneg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006171">
        <property type="entry name" value="TOPRIM_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00204">
        <property type="entry name" value="DNA_gyraseB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00986">
        <property type="entry name" value="DNA_gyraseB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01751">
        <property type="entry name" value="Toprim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00433">
        <property type="entry name" value="TOP2c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56719">
        <property type="entry name" value="SSF56719"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00177">
        <property type="entry name" value="TOPOISOMERASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50880">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 6 8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0799">Topoisomerase</keyword>
    <feature type="domain" description="Toprim" evidence="7">
        <location>
            <begin position="427"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="13"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="50"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="77"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="121"/>
            <end position="127"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="349"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="6">
        <location>
            <position position="461"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="6">
        <location>
            <position position="516"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="6">
        <location>
            <position position="643"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00938"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC92904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="658" mass="72076" checksum="A2812FA6F2F454CE" modified="2018-07-18" version="1">MSTKKPAANPAAYSESSIRVLKGLEPVKQRPGMYTRTENPLHIIQEVIDNASDEALGGYCKHIVVTQNPDGSVTVEDDGRGIPVGLHPEEQVPTVEIVFTRLHAGGKFDKGSGGAYSFSGGLHGVGVSVTNALSSRLEITVWRDAGVHKLTFADGDVIEPLTSQAQTRGDKKAGTRVTIWPNPKYFDTPNISQSDLQRLLRSKAVLLPGVKVTLHAPKETLEWQYEQGLRGYLTESLTSETLIPLFEGAQYATADTDGFAEGEGAAWVVAWCEEGNVVRESYVNLIPTPAGGTHESGLRDGLFGAIKNFVELHALLPKGVKLLPEDVFARASFVLSAKVLDPQFQGQIKERLNSRDAVRLVSTFSKSPLELWLNHHVDYGKKLAELVIKQAQSRLRSAQKVEKKKSSGVAVLPGKLTDCESTDLSRNELFLVEGDSAGGSAKMGRDKEFQAILPLRGKVLNTWETDRDRLFANNEIHDIAVAIGVDPHSMNDTPDLSGLRYGKICILSDADVDGSHIQVLLLTLFFKHFPKLIETGHICIARPPLFRVDAPPRGKKLAQKIYALDSGELMAIEDKLRKEGAKDGSWSIARFKGLGEMNAAQLWETTMNPDTRRLLPVALGEVDQLDSELRFTMLMGKGEAAARRAWIEEHGNDVEADI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYW0</accession>
    <name>A0A2S9GYW0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Polyketide cyclase / dehydrase and lipid transport</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2331</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92914">
        <property type="protein sequence ID" value="PRC92914"/>
        <property type="gene ID" value="S2091_2331"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019587">
        <property type="entry name" value="Polyketide_cyclase/dehydratase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10604">
        <property type="entry name" value="Polyketide_cyc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="176" mass="19558" checksum="1741CD00B5A216B5" modified="2018-07-18" version="1">MNIIKWLFGILVLVVLAVVVLVWSLPNEYNVSRSVVINAPAAKIYPMIAITKEWKNWSVWNQRDPAMLMTYSGPASGVGAEWRWESKSQGNGSMKFLDVVQDQKIVYELSFEGMGKPSSGKLLLTPEGNGTKVTWTMHGNADGNLKMRLFGAVMDKMVGPDFEAGLANLKRNAEHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYX2</accession>
    <name>A0A2S9GYX2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cytochrome c553</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_2349</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92932">
        <property type="protein sequence ID" value="PRC92932"/>
        <property type="gene ID" value="S2091_2349"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00034">
        <property type="entry name" value="Cytochrom_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0349">Heme</keyword>
    <keyword evidence="3 4" id="KW-0408">Iron</keyword>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cytochrome c" evidence="5">
        <location>
            <begin position="13"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC92932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="106" mass="11187" checksum="DDE0C0D80DD0652C" modified="2018-07-18" version="1">MSMTVAANSWAGGDIDAGKAAVEKFGCAACHGVDFKTPIDPTYPKLAGQHQDYLTHALVAYQRGSEVANGRVNAIMNGQAKALSAKDIENITAYIHSLPGSLVLRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZ23</accession>
    <name>A0A2S9GZ23_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Recombination protein RecR</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">recR</name>
        <name evidence="9" type="ORF">S2091_2377</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the RecR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92960">
        <property type="protein sequence ID" value="PRC92960"/>
        <property type="gene ID" value="S2091_2377"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01025">
        <property type="entry name" value="TOPRIM_recR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00017">
        <property type="entry name" value="RecR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000093">
        <property type="entry name" value="DNA_Rcmb_RecR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023627">
        <property type="entry name" value="Rcmb_RecR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023628">
        <property type="entry name" value="Rcmb_RecR_C4-type_Zn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006171">
        <property type="entry name" value="TOPRIM_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034137">
        <property type="entry name" value="TOPRIM_RecR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30446">
        <property type="entry name" value="PTHR30446"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02132">
        <property type="entry name" value="RecR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13662">
        <property type="entry name" value="Toprim_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00493">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111304">
        <property type="entry name" value="SSF111304"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00615">
        <property type="entry name" value="recR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50880">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5 7" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="6 7" id="KW-0234">DNA repair</keyword>
    <keyword evidence="1 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Toprim" evidence="8">
        <location>
            <begin position="80"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C4-type" evidence="7">
        <location>
            <begin position="57"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC92960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="198" mass="21604" checksum="B1B3EAA891DB2E12" modified="2018-07-18" version="1">MKKHASLDGLVEALRRLPGVGPKSAQRMAFHLLQHDRDGLSMLGHACTEALTKIQHCELCNTFTELSVCETCLDAERDTSLLCIVETPADLLMIEQTMTFKGLYFVLMGRLSPLDGVGPKDIHLTKLVQRASNGVVREVVLATNFTNEGEATAHYLGETLKARGLTVTRLARGVPVGGELEYVDAGTLARAMLDRRAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZ41</accession>
    <name>A0A2S9GZ41_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2313</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92896">
        <property type="protein sequence ID" value="PRC92896"/>
        <property type="gene ID" value="S2091_2313"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="52" mass="5752" checksum="D17F600F0C7F8915" modified="2018-07-18" version="1">MFWFNHPQPIDRRKAVPELAVKQTGVAPLSTNMIIVKRPPTVSVAPVLPTSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZ55</accession>
    <name>A0A2S9GZ55_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Methyl-accepting chemotaxis protein (MCP) signaling domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_2404</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyl-accepting chemotaxis (MCP) protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92987">
        <property type="protein sequence ID" value="PRC92987"/>
        <property type="gene ID" value="S2091_2404"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004888">
        <property type="term" value="F:transmembrane signaling receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004090">
        <property type="entry name" value="Chemotax_Me-accpt_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024478">
        <property type="entry name" value="HlyB_4HB_MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004089">
        <property type="entry name" value="MCPsignal_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12729">
        <property type="entry name" value="4HB_MCP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00015">
        <property type="entry name" value="MCPsignal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00260">
        <property type="entry name" value="CHEMTRNSDUCR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00283">
        <property type="entry name" value="MA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50111">
        <property type="entry name" value="CHEMOTAXIS_TRANSDUC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0807">Transducer</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="192"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="6">
        <location>
            <begin position="212"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="domain" description="Methyl-accepting transducer" evidence="5">
        <location>
            <begin position="269"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="519"/>
            <end position="545"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00029447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC92987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="570" mass="60868" checksum="F8E39254DAB4E995" modified="2018-07-18" version="1">MNIANLKIGTRLGIAFAFILTLLIVVAFVGILNMSKMDTGTHELVHVAFVKTKLSYDALDNVRGSMSRVFEMVGMTDDQEIGRVRERLQSNTTKFDDALNKLEPLMSTPEGKELFLKIKETHIGYINSVAKVLGLVSASKHDEASKLAYGETYAALHAFADTLRAMADLQQKHFEQGGEQSEQTYASARNQVTVLSVLAVLLGVFGAVWIARSITVPLVKAVSLAETIASGDLTSQFGVQCEDETGQLMRALQEMNDNLMKIVGEVRVGTETILTASREISQGNLDLSSRTEAQAGALEETASSMEELTSTVKQNADNALQANKLAQNASSVATKGGSVVSNVVDTMGAINTSAKKIVDIISVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVASEVRNLAQRSAAAAKEIKELIGDSVEKVEAGSALVNEAGATMTEVVTSIKLVTDIMAEITAASQEQSQGIDQINQAIVEMDNVTQQNAALVEEAAAAAGSMQEQASNLMEVVNVFKLNNNQVSSSRAAPKKVANTHSHGMQVRGKPNQAFKRPASALIKHTEHKTPVGDDFEEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZL8</accession>
    <name>A0A2S9GZL8_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 4">N-(5'-phosphoribosyl)anthranilate isomerase</fullName>
            <shortName evidence="4">PRAI</shortName>
            <ecNumber evidence="2 4">5.3.1.24</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">trpF</name>
        <name evidence="6" type="ORF">S2091_2243</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:21540"/>
            <dbReference type="ChEBI" id="CHEBI:18277"/>
            <dbReference type="ChEBI" id="CHEBI:58613"/>
            <dbReference type="EC" id="5.3.1.24"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 4">Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 3/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the TrpF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.24" evidence="2 4"/>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93157">
        <property type="protein sequence ID" value="PRC93157"/>
        <property type="gene ID" value="S2091_2243"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00035">
        <property type="reaction ID" value="UER00042"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004640">
        <property type="term" value="F:phosphoribosylanthranilate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000162">
        <property type="term" value="P:tryptophan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00405">
        <property type="entry name" value="PRAI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00135">
        <property type="entry name" value="PRAI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001240">
        <property type="entry name" value="PRAI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044643">
        <property type="entry name" value="TrpF_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42894">
        <property type="entry name" value="PTHR42894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00697">
        <property type="entry name" value="PRAI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="SSF51366"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="4 6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0822">Tryptophan biosynthesis</keyword>
    <feature type="domain" description="PRAI" evidence="5">
        <location>
            <begin position="6"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC93157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="235" mass="25549" checksum="9EECBEDDC78DD033" modified="2018-07-18" version="1">MVTRIKICGLTRKKDVQVALQLGAHALGFVFYPKSPRLVSAEQARELIALLPPFVTSVGLFVNATVEQVLAVLAVAPVNVLQFHGDETPEQCHAIAQAAQRPFIRALRVKDDMCADDLLQCETLYRVSSPWFSGLLLDSFVDSFGGSGKVFDWSVIPKELAPRVVLSGGLTAHNVSGAVVQLRPWAVDISSGVELAKGIKDPAKMRAFVKAVQMADTNLPENEYALQYESQSKSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZT8</accession>
    <name>A0A2S9GZT8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1951</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93213">
        <property type="protein sequence ID" value="PRC93213"/>
        <property type="gene ID" value="S2091_1951"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="79" mass="9203" checksum="3928F52FD3120977" modified="2018-07-18" version="1">MLFGLKKLFFADYLQIYFNFHGIKSGLIAVFTFVNRQLDIQNQSFMSKILPNRMVSSKMIHMVWAKISSLFCVGAQWCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZZ8</accession>
    <name>A0A2S9GZZ8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Response regulator containing CheY-like receiver AAA-type ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_2039</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93301">
        <property type="protein sequence ID" value="PRC93301"/>
        <property type="gene ID" value="S2091_2039"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002078">
        <property type="entry name" value="Sigma_54_int"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025662">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025943">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025944">
        <property type="entry name" value="Sigma_54_int_dom_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00158">
        <property type="entry name" value="Sigma54_activat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00675">
        <property type="entry name" value="SIGMA54_INTERACT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00676">
        <property type="entry name" value="SIGMA54_INTERACT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00688">
        <property type="entry name" value="SIGMA54_INTERACT_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50045">
        <property type="entry name" value="SIGMA54_INTERACT_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Response regulatory" evidence="8">
        <location>
            <begin position="14"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma-54 factor interaction" evidence="7">
        <location>
            <begin position="154"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="6">
        <location>
            <position position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC93301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="470" mass="51071" checksum="0E5DE3E66DF5477B" modified="2018-07-18" version="1">MSKSNEAAPNETAHILLVDDDPDLLTLISMRLRAAGHRVTAVASAEAALARLAIELPALVISDVRLPGRDGLALFDEIRRLHAALPVILLTAHGTIPDAVDATSRGAYAYLTKPFDGTILLEKVTHALSLTAPTSGSGNSDGSDGNGENWRAELISRSQRMAELLTEAKLVAATDASILIQGESGTGKELLARAIHRASPRAKAPFIAVNCGAIPEQLLESELFGHVKGAFTGALAHRNGLFQSANGGTLFLDEIGDMPLPLQVKLLRVLQERMVRQVGADQASAIDVRVLSATHRDLDVAMQEGLFREDLYYRLNVVTLVLPTLAERREDIALLANHFRQQLAEKYGKEINGFAPDALAALMAAAWPGNVRQLHNVVEQVCALATTPLIPLSLVQRALRLPALEVLSYTEAKQRFERDYLIQLLKLTDGNVSDAARLAERNRTEFYRLLQKHDLTASLFRDDPDPVAAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H017</accession>
    <name>A0A2S9H017_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Permeases of the drug/metabolite transporter (DMT) superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2063</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93325">
        <property type="protein sequence ID" value="PRC93325"/>
        <property type="gene ID" value="S2091_2063"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="36"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="91"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="124"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="147"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="178"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="211"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="244"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="267"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="9"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="148"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="294" mass="31356" checksum="0D43C282EE0CE409" modified="2018-07-18" version="1">MFALPRLVALALLTVYLVWGSTYFAIHVALTSFPPFMLMGTRFLAAGSLLFIFLKWRGKTNPTTKQWRDAGLVGSLILGGGMGLTSYAQQYISSGLTAVFIACSPFVLTLCVGMYGEWPNRREWMGILIGFAGALLLASGGDFSAKPIGIVALLGAIICWDLGSVLSQRKFSLAPGAMGFASEMLLGGVFLVVLGYLNGEHFVGTITPSAWFAWSYLVVAGSLGAFTAYMYLIATVPPALASSYSYVNPVIAVTLGVMFAGEKIGTRDIVAMTVILSSVLLITTARNRATKITK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H056</accession>
    <name>A0A2S9H056_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_2103</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93365">
        <property type="protein sequence ID" value="PRC93365"/>
        <property type="gene ID" value="S2091_2103"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000485">
        <property type="entry name" value="AsnC-type_HTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019888">
        <property type="entry name" value="Tscrpt_reg_AsnC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019887">
        <property type="entry name" value="Tscrpt_reg_AsnC/Lrp_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019885">
        <property type="entry name" value="Tscrpt_reg_HTH_AsnC-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01037">
        <property type="entry name" value="AsnC_trans_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00033">
        <property type="entry name" value="HTHASNC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00344">
        <property type="entry name" value="HTH_ASNC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00519">
        <property type="entry name" value="HTH_ASNC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50956">
        <property type="entry name" value="HTH_ASNC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH asnC-type" evidence="4">
        <location>
            <begin position="2"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC93365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="152" mass="17072" checksum="93F890826D9D1409" modified="2018-07-18" version="1">MLDKISKRILAELQNDGRISNVELANRVNLSPAACLERVRKLQESGYILGYTAQLNPQLLDVALLVFIEVVLDRTTPDVFDAFKRGVQAIPEVLECHMVAGGFDYLVKARVKDMNAYRDFLGKSLLQLGGVRETHTYAVMEEVKNTTHLPIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H078</accession>
    <name>A0A2S9H078_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="8">CydB: cytochrome d ubiquinol oxidase, subunit II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_1768</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome ubiquinol oxidase subunit 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93381">
        <property type="protein sequence ID" value="PRC93381"/>
        <property type="gene ID" value="S2091_1768"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003317">
        <property type="entry name" value="Cyt-d_oxidase_su2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43141">
        <property type="entry name" value="PTHR43141"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02322">
        <property type="entry name" value="Cyt_bd_oxida_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000267">
        <property type="entry name" value="Cyt_oxidse_sub2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00203">
        <property type="entry name" value="cydB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="78"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="122"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="164"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="204"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="264"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="293"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="339"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC93381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="379" mass="41425" checksum="6C07FB9396EEFF1A" modified="2018-07-18" version="1">MIFDYETLKVIWWGIIGVVIIGFAVTGGFDLGVGMLLPWVGKTDDERRVLLNSVGPTWEGNQTWFITAGGATFAAWPLVYSAAFSGLYTALLLLLFTFILRPVGFDYRSKLADPRWRSCWDWGLFIGGLVPALIFGVAFGNLLIGLPFDYDMFMRVTYHGGLLGLLNPFGLLAGLISVAMLLMHGASFLHTKTEGAIANRSKHVASVAAIVSAALFIAGGFWVSHLDGMRILTMPDANSAFVPAAKTVALATGAWLDNYARWPLLWALPTTTILLMLLCALGNKLNYARSAFIASGLAVTGIILTAGASLFPFIMPSTMAPNNSLTVWDAVSSHRTLSIMFWVTLVMVPIIVTYTSWVYRIMRGKVTVEHIQENQHSSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H099</accession>
    <name>A0A2S9H099_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1784</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93397">
        <property type="protein sequence ID" value="PRC93397"/>
        <property type="gene ID" value="S2091_1784"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="SSF48208"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="678" mass="75339" checksum="640F9A89E8ECDF2D" modified="2018-07-18" version="1">MIASRLKKIMAYGFLIAFNLLGPAVVNAEIIPTLHPRWTIQQNGIQTSATDQHTDQLEMSGRQVSTIIDYGRDVNGSLNLRRTLVWPMLRTIPDDTHASLIRKFELADSPSIEIDGHVAPKETLRKIRYDGQLTLDSELMRGLSLTRLLSPATDEPALIERLTLTNHTDTVIAYRFDALNKTETTPAQAGTHGSYLIRAFSRASSGSLKSGQSMHVDVLYQAQLVNEMVYVDVNEQLAARRQKLQSWRSRLVLDTPEPVLNQMFEFAKIRAAESIFATRGGLLHAPGGGRYYAAIWANDQAEYANPFFPYLGDASGVEAALNSFRLFAGYMNPTYQPIPSSIIAEGRGFWNGAGDRGDCAMIAYGAGQFALAQGDAALAEQVHPLINWCLEYTRRQRDAAGIVHSDSDELEGRFESGKANLSTNVLAYASLIGAARLSQDPQERSALNEEAQLQRSAINRYFAANVGGFDTYRYYDGNTKLRAWIALPLVFGMEERKAGTVAALLSPQLWSLNGVLSEAESNTYWDRATLYGFRGLMKVGELEQVMPYFRYYSGMRLTGEHVPYAIEAWPEGNQRQLSAESALYARVIVEGLFGIEPVGLRSFNIAPRLPKAWPHMALTNIRAFGAGFVDGQVSESGLDISTTRIKQQRQHVQVRLHGKLIVDRDWDGHAMINVILPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0C0</accession>
    <name>A0A2S9H0C0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">UbiA prenyltransferase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_1816</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93429">
        <property type="protein sequence ID" value="PRC93429"/>
        <property type="gene ID" value="S2091_1816"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016765">
        <property type="term" value="F:transferase activity, transferring alkyl or aryl (other than methyl) groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000537">
        <property type="entry name" value="UbiA_prenyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044878">
        <property type="entry name" value="UbiA_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01040">
        <property type="entry name" value="UbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="50"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="92"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="116"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="169"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="198"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="228"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="270"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC93429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="306" mass="32859" checksum="EC2B9CEED443BB6E" modified="2018-07-18" version="1">MTPSHIKIIQPSVFLRLGRVSNLPTIWSNALAGTMLSGATLNEATANLKLFWVMLALTAFYVAGMYLNDAFDAGFDAKNRIRRPIPSGEISRFYVFTIGYFLLGIGVFLLARYGNTSLVCGVSLAFVIVLYNIWHKGNPASPLLMGVCRMLVYFAAASCANGGQFGLPLLLGAVALFSHIVGLTYAAKQEAHNQLGQLWPLMVLALPVLYYAFTVLSPQNDFAGHNMFIGLGLVAALITSNALALRHLLRPAQLRAVPAAVTQLIATTSILDALAVYSMGASISAILFCLAAYVLTRLLQTVIAGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0H9</accession>
    <name>A0A2S9H0H9_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_1850</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93463">
        <property type="protein sequence ID" value="PRC93463"/>
        <property type="gene ID" value="S2091_1850"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013767">
        <property type="entry name" value="PAS_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00989">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PAS" evidence="5">
        <location>
            <begin position="10"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="6">
        <location>
            <begin position="87"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="5">
        <location>
            <begin position="139"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="6">
        <location>
            <begin position="216"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="4">
        <location>
            <begin position="284"/>
            <end position="495"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC93463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="499" mass="56037" checksum="D50AEA568A8E2C70" modified="2018-07-18" version="1">MTKHFLEIPEGRQLNWLLESASDAMLITNIEGRIILANPPLLRMFGYLSEELLDNPIETLLPERVRHGHVGMRTDYFVRPSARAMGSGRELSGRHKNGTEFFVEVSLSPLQTEQGDTLVMATIQDITARKQAEKSLLESEARMRAIVDTAVDAIITIDETGIIERFNPAAQVLFGYIETDIKGRNISTLMPSPFREMHDGYLAKYLTTGEKKIIGIGREVVGLRKDGTVFPMDLSIAEMQIGKRRMFTGIVRDISERKLAEEKNTRLMQEISSANEELTSFAYVVSHDLKAPLRAIGSLADWLSTDYADKFDDEGREHMRLLISRVHRMGGLIDGILQYSRIGRIKETVVEVDLNRVVAEVIDLLAPPSSITVTVDALPKIKIEPTRIEQIFQNLISNAIKYMDKPDGKIHVGFSGADKDNWQFSVTDNGPGIEPRHFERIFQLFQTLAPRDRIESTGVGLALMKKSVEMYGGKVTLESTPGTGSIFSFTLRKHPKNQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0P2</accession>
    <name>A0A2S9H0P2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nucleoside-diphosphate-sugar epimerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1910</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93523">
        <property type="protein sequence ID" value="PRC93523"/>
        <property type="gene ID" value="S2091_1910"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="1">
        <location>
            <begin position="18"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="345" mass="38402" checksum="F9FA3B7E383982CF" modified="2018-07-18" version="1">MTTYHEVQQKLKQQQSCWLITGVAGFIGSNLLETLLKLNQKVVGLDNFSTGYQHNLDQVRELVGSSAWSNFTFIKGDICNLNDCQQACAGVDYVLHHAALGSVPRSIEDPLLTNASNVTGYINMLVAARDHQVKRFVYAASSSTYGDHPDLPKVESVIGKPLSPYAVTKYVNELYADVFQRCYGISSIGLRYFNVFGPRQDPNGAYAAVIPQWIAALIQNRALYINGDGETTRDFCYVENVVQANILAALTTDSAAINQVYNVALNDSTSLNQLYQMMRAALIDSFAHIREHQPSFQTFRAGDIRHSQADISKARELLGYAPAYRVDQGLSKAMDWYKHDLANRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0V6</accession>
    <name>A0A2S9H0V6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">BlaR1 peptidase M56</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_1598</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93597">
        <property type="protein sequence ID" value="PRC93597"/>
        <property type="gene ID" value="S2091_1598"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011055">
        <property type="entry name" value="Dup_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016047">
        <property type="entry name" value="Peptidase_M23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008756">
        <property type="entry name" value="Peptidase_M56"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01551">
        <property type="entry name" value="Peptidase_M23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05569">
        <property type="entry name" value="Peptidase_M56"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51261">
        <property type="entry name" value="SSF51261"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="46"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="119"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="230"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="298"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="330"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M56" evidence="3">
        <location>
            <begin position="12"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M23" evidence="2">
        <location>
            <begin position="407"/>
            <end position="507"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC93597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="532" mass="58340" checksum="D0D342373A5F1CDA" modified="2018-07-18" version="1">MNEIITNFSLLFLQASISCTVVALIVWGVLALAVRIWPGLSIQRSVWLLAQVAIGVAFLLVWVPQTAHLSILPTFTIAATSKHDMPTHIDMARPIVEQTKLTDPASDEEVGTFNVTHLAWIWLAVYSAGLALNLTRWLLAKRKLQALLTTSEVLTGEALRTHPALNELPEYALNRVQIMETSAAVSPMLVGVGLNKTTRLLLPQHLRSFNTEQQRLIVAHELTHWRRHDLLFLHLSTLLQTLFWFNPILRSLGKRLNWAQELGCDQQVLTGRSQQQRQHYAAALVGQLKAQQALFDTALPALAFGAMQGATLATRINLIRRNTLPNSNWLSKYTVAAGLAGVLICSMLLQPAFALHDESVDLSTSVVTNQNAHATESTATLPQWSNPVSDVHINAFYGVQGKLTPNGHHGIDFSAKLGTPVLAMADGTVIASTEQWENDPHYGRGRVVVIQHPDNLRSLYAHLGSSTVKVGDVIKAGQVIAYSGASGKVTGPHLHVEAWQGEQLIDPQRLLAGLDEHASQSALRARNAIKMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0W0</accession>
    <name>A0A2S9H0W0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Biopolymer transport protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_1623</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Membrane</location>
            <topology evidence="1 6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the exbB/tolQ family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93622">
        <property type="protein sequence ID" value="PRC93622"/>
        <property type="gene ID" value="S2091_1623"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002898">
        <property type="entry name" value="MotA_ExbB_proton_chnl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01618">
        <property type="entry name" value="MotA_ExbB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="17"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="128"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="174"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="domain" description="MotA_ExbB" evidence="8">
        <location>
            <begin position="75"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC93622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="246" mass="25914" checksum="047A665451A64250" modified="2018-07-18" version="1">MSANPYSIETLLTDGDFVTRGVTFLLIAMSIASWLVIVTKSLQLWRYRHSSKAAGQTFWDTTSVSEGLSTLGKENPFSDIAQAGVTAMRHHTAHKGHLHDQLTVSDWVTLSLRQAIDETTAKLQAGMAILASVGSTAPFVGLFGTVWGILHALVSIGTSGQAGIEQVAGPVGEALIMTALGLAVAIPATFGYNVLVRGNKNIIAKLNKFGFDLHALFVTGARSTDETKNAPAKLVAVPVVANMGAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0Z6</accession>
    <name>A0A2S9H0Z6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1639</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93638">
        <property type="protein sequence ID" value="PRC93638"/>
        <property type="gene ID" value="S2091_1639"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="28"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="60"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="100" mass="11220" checksum="DDBF3E9D2211A956" modified="2018-07-18" version="1">MESANSIDVTTEKINAIRRAKALAVIEWPMSILTQLIALFFMIAIPISCVWVSIVSKAELPLYSSIFLLLPTIIFVAGMLMNTQRRLEALTEPVKQDLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H127</accession>
    <name>A0A2S9H127_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">TDP-4-keto-6-deoxy-D-glucose transaminase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_1567</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the DegT/DnrJ/EryC1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93566">
        <property type="protein sequence ID" value="PRC93566"/>
        <property type="gene ID" value="S2091_1567"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00616">
        <property type="entry name" value="AHBA_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000653">
        <property type="entry name" value="DegT/StrS_aminotransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012749">
        <property type="entry name" value="WecE-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30244">
        <property type="entry name" value="PTHR30244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01041">
        <property type="entry name" value="DegT_DnrJ_EryC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000390">
        <property type="entry name" value="PLP_StrS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02379">
        <property type="entry name" value="ECA_wecE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="185"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="2">
        <location>
            <position position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR000390-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000390-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC93566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="383" mass="43147" checksum="7322A7960D415AE0" modified="2018-07-18" version="1">MTNKRIPFNWPHMTGKELYYIAEAHFNGRLAGDGPFTKLCHNWLQERTGSSKALLTHSCTASLEMAALLLDIQPGDEIIMPSYTFVSTANAFVLRGGIPVFIDIREDTLNINERFIEPAITPRTRAIVPVHYAGIACEMDTIMSIAKNHNLKVVEDAAQGVMATYKGRALGSIGDLGAYSFHETKNVISGEGGALLINDHKLSLRAEIIREKGTNRSQFYRGEVDKYTWQEIGSSFLPGELIAAFLWAQFEEADKITQKRMVAWQRYHELLAPLESSGVIRRPVIPKECHHNAHMYYVILGPEIDRQKILDVLNRNDINAVFHYVPLHSSPAGLRYARAHGSLEITNKLSERLLRLPLWVDITESKQNKVIDVLKEAIYSATH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H174</accession>
    <name>A0A2S9H174_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein required for cytochrome oxidase assembly</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_1694</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93693">
        <property type="protein sequence ID" value="PRC93693"/>
        <property type="gene ID" value="S2091_1694"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016653">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006784">
        <property type="term" value="P:heme A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003780">
        <property type="entry name" value="COX15/CtaA_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02628">
        <property type="entry name" value="COX15-CtaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0350">Heme biosynthesis</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="32"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="103"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="133"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="158"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="197"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="270"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="300"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="326"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC93693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="357" mass="39329" checksum="4A5B27436A1D4217" modified="2018-07-18" version="1">MWIQIVLTALLVAALPLTIVWVSSDANKYRKLVLVTLFLTFDLIMFGGFTRLTDSGLGCPDWPGCYGAANPFISHAAISAAQTAMPEGPVTHFKAWVEMIHRYLAASVGVLIVAQMIIAWIKRKQFEGAPVYATVLFLFVCLQGAFGMWTVTLKLQPIIVTTHLLLGMGLLVMLAWLAARIETVPIRVAHEALKLKWLARAAWLILLIQIALGGWVSTNYAVLACTDYPMCQGALIPPMDFEHGFSLWRELGKTANGDYLSFAALTAIHWVHRNFALLVVISSGYVAFRARNMMGVSKVAKAIMLVLLVQFCTGLANILFNWPLGIAVLHNGGAALLLGLLTVLNYRVQIPVDLRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1E6</accession>
    <name>A0A2S9H1E6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acetyltransferase (GNAT) family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1687</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93686">
        <property type="protein sequence ID" value="PRC93686"/>
        <property type="gene ID" value="S2091_1687"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13508">
        <property type="entry name" value="Acetyltransf_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="6"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="143" mass="16300" checksum="0F2113B6AE99F47A" modified="2018-07-18" version="1">MTSPEIQISSDKAKLNIDFIHAELACKYWSIGIPRSIVETAIAHSLCFGVYLNESQIGFARVTSDVATFAYLSDVFILDQYQGQGYAKRLISEIQAHPQLQGLRRWMLMTQDAHSLYTQFGFKALAHPERAMEKNQPNIYQKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1F7</accession>
    <name>A0A2S9H1F7_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">FAD-binding PCMH-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_1407</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93798">
        <property type="protein sequence ID" value="PRC93798"/>
        <property type="gene ID" value="S2091_1407"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1060.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004017">
        <property type="entry name" value="Cys_rich_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021817">
        <property type="entry name" value="DUF3400"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022153">
        <property type="entry name" value="DUF3683"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016164">
        <property type="entry name" value="FAD-linked_Oxase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004113">
        <property type="entry name" value="FAD-linked_oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009051">
        <property type="entry name" value="Helical_ferredxn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02754">
        <property type="entry name" value="CCG"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11880">
        <property type="entry name" value="DUF3400"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12447">
        <property type="entry name" value="DUF3683"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02913">
        <property type="entry name" value="FAD-oxidase_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13183">
        <property type="entry name" value="Fer4_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55103">
        <property type="entry name" value="SSF55103"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="SSF56176"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="4">
        <location>
            <begin position="187"/>
            <end position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC93798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="1325" mass="147299" checksum="7E7298769FA6A283" modified="2018-07-18" version="1">MNAPVQIQALNLPHPDAAPTRLREIPYNYTSFSDREIVIRLLGEPAWHLLDTLRVARQTGRSARMLYEVLGDIWVVQRNPYLQDDLLDNPKRRQNLIDALNHRLAEVDKRRLDDAEQGDDAKQRSQSVQTLLQAARLAVQKFAEEFRNTYDLRKRAIRLLAKHTEKDNIKFDGLSRVSHVTDATDWRVEYPFVVLTPDTEDEMAGLVKCCIELGLTIIPRGGGTGYTGGAIPLTPRSAVINTEKLETLGAVEMTVLPGLSAPYATIYSGAGVVTKRVTDAAEKAGFVFAVDPTSAEASCIGGNVAMNAGGKKAVLWGTALDNLASWRMVDPNGDWLEVTRLEHNLGKIHDVAVAKFKLEWTHPGQKTPFKTEQLDIKGRTFRKEGLGKDVTDKFLAGLPGVQKEGCDGLITSARWILHKMPKFTRTVCLEFFGQARDAIPSIVEIKDYLDGQTKQGGAILAGLEHLDERYLRAVGYTTKSKRGVLPKMALFGDIVGDDENAVALAASEVIRIANTRVGEGFVAVSPEARKKFWLDRAKTAAISKHTNAFKINEDVVIPLDRMGEYTDGIERINIELSLQNKLALVQSLRQYFANGNLPLGKNEDAEGDDIPAAEIFEDRVAQAQTLLDAVHTRWQTVLDQLDQPLASCMTQFVAIGLEKLIPVFEVRLTTQPDATLFDVVQDRTIRISWKNELRAQLRQIFTGSAFKLILDECIATHKKILRSRVFVALHMHAGDGNVHTNIPVNSDDYDMLQVAHTAVARIMVLARHLNGVISGEHGIGITKLEYLNEAEIQDFRDYKLRVDPEGRFNKGKLLNLPGFDADLRNAYTPSFGLMGHESLIMQQSDIGAIANSVKDCLRCGKCKPVCATHVPRANLLYSPRNKILATSLLVEAFLYEEQTRRGISIKHWEEFEDVADHCTVCHKCVTPCPVDIDFGDVSMNMRNLLRKMNKKSFNPGTATSMFFLNAKDPATIKAARKVIFGWGVAAQHLANTLLKSLAKKQTKAPPSTVGKAPIKEQVIHFINKKMPGNLPKKTARALLDIEDDKVVPIIRNPQTTNADTEAVFYFPGCGSERLFSQVGLATQAMLWHVGVQTVLPPGYLCCGYPQRSSGDFEKGEKIITDNRVLFHRMANTLNYLDIKTVVVSCGTCYDQLAGYQFDKIFPGCRMLDIHEYLLEKNVKLEGVTGTRYMYHDPCHTPMKLQDPLKTVNALITTVDDQKIEKNDRCCGEAGTLAVSRPDVSTQIRFRKEEEMIKGADKLRADGFTGDVKILTSCPACLQGLSRFNDDSGSTADYIVVEIAKHLLGENWMPDYVANANNGGIERVLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1H9</accession>
    <name>A0A2S9H1H9_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 13">Error-prone DNA polymerase</fullName>
            <ecNumber evidence="3 13">2.7.7.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">dnaE2</name>
        <name evidence="15" type="ORF">S2091_1454</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12 13">
            <text>a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 13">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the DNA polymerase type-C family. DnaE2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="3 13"/>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93845">
        <property type="protein sequence ID" value="PRC93845"/>
        <property type="gene ID" value="S2091_1454"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01902">
        <property type="entry name" value="DNApol_error_prone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011708">
        <property type="entry name" value="DNA_pol3_alpha_NTPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040982">
        <property type="entry name" value="DNA_pol3_finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023073">
        <property type="entry name" value="DNA_pol_error_prone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029460">
        <property type="entry name" value="DNAPol_HHH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004365">
        <property type="entry name" value="NA-bd_OB_tRNA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004013">
        <property type="entry name" value="PHP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003141">
        <property type="entry name" value="Pol/His_phosphatase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016195">
        <property type="entry name" value="Pol/histidinol_Pase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004805">
        <property type="entry name" value="PolC_alpha"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32294">
        <property type="entry name" value="PTHR32294"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32294:SF4">
        <property type="entry name" value="PTHR32294:SF4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07733">
        <property type="entry name" value="DNA_pol3_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17657">
        <property type="entry name" value="DNA_pol3_finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14579">
        <property type="entry name" value="HHH_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02811">
        <property type="entry name" value="PHP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01336">
        <property type="entry name" value="tRNA_anti-codon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00481">
        <property type="entry name" value="POLIIIAc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89550">
        <property type="entry name" value="SSF89550"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00594">
        <property type="entry name" value="polc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 13" id="KW-0227">DNA damage</keyword>
    <keyword evidence="11 13" id="KW-0234">DNA repair</keyword>
    <keyword evidence="7 13" id="KW-0235">DNA replication</keyword>
    <keyword evidence="10 13" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="6 13" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="POLIIIAc" evidence="14">
        <location>
            <begin position="12"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00017273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00024632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="PRC93845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="1044" mass="116642" checksum="DDCB95864FABCFA7" modified="2018-07-18" version="1">MSTSSSTLSTYAELQCFSHYTFLRGASSPEQLVQRAVKLGYHSLAITDECTLAGVVKAHVEAKRLGLHLIVGSQIRITPEDGSNAFNLIILAMNKNGYGNLSELITVARTRIEKGSYLARPRDIADPGDELKHLKGLPDCQIILAPDYGIAYEKLERQAAWLLQCAPGRARIALTLHHRVQDEMHKAVVNAIATEYGLPVTATGDVCMHVRSYKPIQDTMTAIRIGVPIAQCGYQLAPNAEQHLRSRLRLNNLYTRAALNETVQVASLCTFSLDELKYDYPDELVPDGATPTSYLRQESYIGAQWRYPSGIPKNVQAQLEYELQLIAEMQYESYFLTVFDIVRFARAQRILCQGRGSAANSAVCYCLGITEVDPARSTLLFERFISKERNEPPDIDVDFEHQRREEVIQYIYNKYGRRRAALTAVVTTYRPRSVLRDVGKALGVDLSVVDKVAKASHGWYGSADLRQRLTECGFDPDSALAEKWSELAEKLMRFPRHLSQHPGGFIISHTKLSRLVPIENASMADRSVVQWDKDDIDAVGLMKIDILALGMLSCLRRTLELVAQRNGEPFELQDIPAEDSATYDMLCKADTIGVFQIESRAQMSMLPRLQPRKFYDLVIEIAIIRPGPIQGGMIQPYLRRRQGLEPISYPGPAMEAVLSRTLGIPIFQEQVMQIAMVAAGFSAGEADQLRRAMAAWKRKGNLEQFEEKLTSGMAEREYSPEFATSIISQIRGFAEYGFPESHASSFALLAYASSWLKCHEPAAFLTALLNSQPMGFYSPSALIQDARRHGVVVLPVDVTTSDWDSRLEPDAAVCLGMNNVSGFEREAGWRIEEARAIRPFSDMRDLASRAQLNARHIRALAAANALFTLAGNRRQALWQAVASVPDKGLLRPTTIEEAEVHLEAPTEGQNIVADYRHLGLTLGRHPLALLRKKLSAMRFSTSEILHTYPDGKLARGCGIVTVRQRPETAKGVTFVTIEDETGNVNVIVWPDLAEKQRIELSNARLLGVYGKWQSQHNVRHLVAMRLVDLSHFLGELETRSRDYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1T7</accession>
    <name>A0A2S9H1T7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Acetyltransferase (GNAT) domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1128</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC93955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93955">
        <property type="protein sequence ID" value="PRC93955"/>
        <property type="gene ID" value="S2091_1128"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="285" mass="32200" checksum="E2E88C9DF40F5C93" modified="2018-07-18" version="1">MLTFAPIKFDNKTLALYVSLFSTCFPKSTKFTPEYLQWLYCKNPAGLAIGFDAWDGEILAAHYVCVPTFVSINGVKVQALLSLNTATHPLYQGKGLFTKLAEQTYSAGAENNFDCVYGVANANSTPGFIGKLGFQLVDQLDARFGVGHLNIDFEVAKRNTQFERIWSADCLNWRCSNPENTVYQYKHSDFRQFYASSVWKSFPVYAETLNDQAMDLNRSERKKFLPVRLFLGLIPDGASQDMKYLTIPLRLRPSPLNLIFRSLTGNVQKIEKGHASLSFLDFDAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1U5</accession>
    <name>A0A2S9H1U5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Methyltransferase domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1134</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC93961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93961">
        <property type="protein sequence ID" value="PRC93961"/>
        <property type="gene ID" value="S2091_1134"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="287" mass="31771" checksum="4A779155D749138C" modified="2018-07-18" version="1">MQKFFSRLSNLFKAEVVIEPKLAPLISEQGVVDSRICGLMDAVQSGWFNQASGELVAGFPIASNDVVLDVGCGDGAATLFAARCGAEVIFSDSNAEKIAKLSLIVKSVPARKWQALVCETDPLPLPDGRASRIIAMEMLEHVDDPAQVLAELVRVGQPGALYLLTVPDPVGEHVQQQIAPAVHFQKPNHIHIFERDHFAAMISNAGLKIENRQSSGFYWTMWMCLYWASAPQQQDATLDQIKQPYPPLLNEWANTWHQLMLTPDGNKVKEKLDSFMPKSQIIIARKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1W6</accession>
    <name>A0A2S9H1W6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyl transferase family 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1145</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC93972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93972">
        <property type="protein sequence ID" value="PRC93972"/>
        <property type="gene ID" value="S2091_1145"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="2">
        <location>
            <begin position="4"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="232" mass="26516" checksum="DBD4FB34A45F7830" modified="2018-07-18" version="1">MKFSLIIPCYNEAENLPLLLERCKALATMSEVEVILVDNGSTDSTPQVLLNMLPMYPGCRTVRVEKNQGYGFGILSGLRAAKGEILGWTHADMQTDPQDALSGLDLFEKHGTDIFVKGHRYGRPFADVIFTIGMSFFETLLLARPMWDINAQPTMFPRKFFESWSSPPDDFSLDLYAYYQAQTQGLKVHRFPVKFGERAHGVSHWNVNWAAKWKFIRRTIDFSLQLKKKISI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1Y9</accession>
    <name>A0A2S9H1Y9_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Large-conductance mechanosensitive channel</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">mscL</name>
        <name evidence="11" type="ORF">S2091_1165</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Homopentamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cell inner membrane</location>
            <topology evidence="10">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the MscL family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC93992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93992">
        <property type="protein sequence ID" value="PRC93992"/>
        <property type="gene ID" value="S2091_1165"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008381">
        <property type="term" value="F:mechanosensitive ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00115">
        <property type="entry name" value="MscL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019823">
        <property type="entry name" value="Mechanosensitive_channel_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001185">
        <property type="entry name" value="MS_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037673">
        <property type="entry name" value="MSC/AndL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036019">
        <property type="entry name" value="MscL_channel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30266">
        <property type="entry name" value="PTHR30266"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01741">
        <property type="entry name" value="MscL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01264">
        <property type="entry name" value="MECHCHANNEL"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81330">
        <property type="entry name" value="SSF81330"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00220">
        <property type="entry name" value="mscL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01327">
        <property type="entry name" value="MSCL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="4 10" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9 10" id="KW-0407">Ion channel</keyword>
    <keyword evidence="7 10" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="79"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC93992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="139" mass="15224" checksum="28D6333D2401F73F" modified="2018-07-18" version="1">MAMMQEFKSFITRGNVVDLAVGVIVGAAFSKIVDSLVQDVIMPVVGKVVGGLDFANYYLPLNHQDTNLTLVEAKKLGAVFAYGNFLTIVLNFLILAFIIFQMVRLVNSARKKAEEAPAAPAATPEEVLLLREIRDLLNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H225</accession>
    <name>A0A2S9H225_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1214</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94041">
        <property type="protein sequence ID" value="PRC94041"/>
        <property type="gene ID" value="S2091_1214"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="54"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="86" mass="9064" checksum="2E972321D1454898" modified="2018-07-18" version="1">MKPATQSHSKHARISSNIILGLGLLADPVLALDKVVDDDGNKAQRVVISRSLRAAGSGCSTSSHPAIFHPPSVDGYRSNRTDRSAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H248</accession>
    <name>A0A2S9H248_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1222</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94049">
        <property type="protein sequence ID" value="PRC94049"/>
        <property type="gene ID" value="S2091_1222"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002577">
        <property type="entry name" value="HTH_HxlR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01638">
        <property type="entry name" value="HxlR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51118">
        <property type="entry name" value="HTH_HXLR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH hxlR-type" evidence="1">
        <location>
            <begin position="21"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="117" mass="13077" checksum="B7A194D5B28CE515" modified="2018-07-18" version="1">MNTQKKADKHLSQSTDCDATCPVQRTAKILDGKWTTLIVRDLIGGKKRYSELQRSLVGISPRLLAARLRLLEQHGMVIRTAYPTIPPTTEYELTPYGHGLTEIIEAMARFGAGIKRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H277</accession>
    <name>A0A2S9H277_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="9">ABC transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_1139</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ABC transporter superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC93966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93966">
        <property type="protein sequence ID" value="PRC93966"/>
        <property type="gene ID" value="S2091_1139"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03220">
        <property type="entry name" value="ABC_KpsT_Wzt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10147">
        <property type="entry name" value="Wzt_C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015860">
        <property type="entry name" value="ABC_transpr_TagH-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029439">
        <property type="entry name" value="Wzt_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14524">
        <property type="entry name" value="Wzt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-1278">Translocase</keyword>
    <feature type="domain" description="ABC transporter" evidence="8">
        <location>
            <begin position="24"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="58"/>
            <end position="65"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC93966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="415" mass="46330" checksum="17FC0B1464B59EBF" modified="2018-07-18" version="1">MGKVTVKGLGKAYKSYGNRWGRLVEWLSPTSTPRHQLHWVLQDISFELAAGEAVGIVGMNGAGKSTLLKVITGTTQATTGTVEIQGRVAALLELGMGFHPDFTGRQNAIMACQLRGLHVDEIEALMPAIEAFAEIGDYIDEPLRTYSSGMQMRLAFSVATAHRPDVLIVDEALSVGDAYFQHKSFSRIREFRKAGTTLLIVTHDRYAIQTICDRAILLNRGKLEMQGDPIEVMDFYNAMLAEREQQTVRQERLADGRLRTISGTGEASIVAVNLFDDKNKKLDVVEVGTIVTLEIEVKINNPVERLVMGYMIKDKLGQSIFGINTHRLDQPQTDLLPGENLVYRCRFPMNLGKGSYSIAISLSRLDSHLDTNYEWRDYSIIFHVINTRHPDFVGCAFLDAQIDVERSHSLRATIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H291</accession>
    <name>A0A2S9H291_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Aldolase_II domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1149</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC93976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93976">
        <property type="protein sequence ID" value="PRC93976"/>
        <property type="gene ID" value="S2091_1149"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.225.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001303">
        <property type="entry name" value="Aldolase_II/adducin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036409">
        <property type="entry name" value="Aldolase_II/adducin_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00596">
        <property type="entry name" value="Aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01007">
        <property type="entry name" value="Aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53639">
        <property type="entry name" value="SSF53639"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldolase_II" evidence="1">
        <location>
            <begin position="12"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="343" mass="38389" checksum="9759B51A4A9663BF" modified="2018-07-18" version="1">MMSTQINSTAEQVKAYCTRIGKDPLLVQGAGGNVSWKDGSILWVKASGTWLADAEQKDIFVPIDLPHLLKALDDGDFSVEPRLCRESLLRPSIETLLHALMPSRVVVHLHAIEVLAHLVRDNFQADFESLLDESTPWAVVDYYKPGSALAAEISATLTQKPTTKVIFLRNHGVVIGGADVAEADQIICKLTLALSTRPADICPPSHLMFLPPANLIDQYAPVADLDIHQLALTPDLFNRVNSDWALYPDHVVFLGPRAYVYQTWEAFNDQKIFLIELPELVFVKGKGVYAKSSFNKAKQVQLRCYFDVIVRQKPHSSMRVLTDIQIAELLNWDAEQYRMNLAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2A3</accession>
    <name>A0A2S9H2A3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Bacterial regulatory protein, tetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1263</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94090">
        <property type="protein sequence ID" value="PRC94090"/>
        <property type="gene ID" value="S2091_1263"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="9"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="32"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="202" mass="22557" checksum="76544F9C06DE4352" modified="2018-07-18" version="1">MDTQTEKSELTLAAIINTALDMVATQGLESLSLGEVAKRLGISKSGVFSRVGSREALREAVLAEFDRRFADAVFKPAMALPRGLPRLNGLVMGWIGRACNVTGCIYVAGAFEYDDVDSPIRECLQTNILQWRGILRRTVIQALDAGHLRSDTDPEQLVFEIYSLMVGLMHDARFLRDPKAQDRVCSAYKRLISTYRSFNYHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2U0</accession>
    <name>A0A2S9H2U0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cupin domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0901</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94280">
        <property type="protein sequence ID" value="PRC94280"/>
        <property type="gene ID" value="S2091_0901"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.910.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013096">
        <property type="entry name" value="Cupin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016084">
        <property type="entry name" value="Haem_Oase-like_multi-hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039068">
        <property type="entry name" value="PqqC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40279">
        <property type="entry name" value="PTHR40279"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07883">
        <property type="entry name" value="Cupin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48613">
        <property type="entry name" value="SSF48613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cupin_2" evidence="1">
        <location>
            <begin position="322"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="409" mass="45243" checksum="58188787C3DFD85E" modified="2018-07-18" version="1">MTLLMETEAVTILQSTAPAGMSLMWNNWLQEDALQDLVQHPLLLALGRNEASLGVLKTLLVQHSHYSRNFTRYLCSLLGQLTEASDIMALLENLREEMGVDGMGDMTHAEMFQRTLRIVGVTPDEHAALPATTAMVQTMMGYCQSNDPLAGLAAMCLGAEAIVPLVYRPILQALQHFGYGKDATEFFRLHIEEDEDHAITMLNILRRLTLDKPERRELAIQIGRELIGKRVAMFDSIWNNVQNSSATPAASTLAPVNGTRFSSADFGNVPARLKVTMPERLKHPMVMQTNNAADQAFSSDRKHKVHIVDLPTNTISMTIGRLDVAESTRLHRHNYETVMYILAGSGYSVVGERRVPWQAGDAVYIPVWAAHQHVNTGDVECAYLACENAPLLQNLGGIALREELGALTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H335</accession>
    <name>A0A2S9H335_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1016</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94395">
        <property type="protein sequence ID" value="PRC94395"/>
        <property type="gene ID" value="S2091_1016"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="533" mass="59006" checksum="3ADD21E3FE5D12D0" modified="2018-07-18" version="1">MTFEALAYFHDFNVSDFPQEWLPLTYLYDPDLPLFPILYFHELDPTLDATQRPGERDRIFGFVHSIAYDRSLGVLRVTLASSKDLSLHVNSRFVDIAKMAARSRLGLDNPVVLNDITGALTNSLVAANALLRELWIQIVASSFGGKLPFGKCWDAIFGLARYIASWNSEGGRKGELIQLHAYVAAFGERIQTGGGIHADFYLLPTWSEFRDNSNPLALFSKYSSLVGPSGATVFFSNAFTNIVNLGSSSYSRFELNNVRISTGNNFRNLNTDALVALIEQAPRGRVRTALYDNYSAFNRGPGRAILSLLMHHDLRTGKWNPEKLTQQDCISQYTGLSSSYQSPKVMQLYAQQCFGSLPALPIDNWVKTFLSAPIGLSVAPRNFHATIFASSTVWGKVERLIWMAAQARKVHSSVAENILWCVRYGGPAKEMRSANPLSCKVCDTHIRAACPSYASIQNMNITFNLVSAPPNGFNVRTSSGDNLNQNQTFTASEGLNAYDEYTTKDRPSQFAAYPSPNHAGGAAMTVSNFINTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H356</accession>
    <name>A0A2S9H356_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">AMP-binding enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1008</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94387">
        <property type="protein sequence ID" value="PRC94387"/>
        <property type="gene ID" value="S2091_1008"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="420" mass="45355" checksum="0DA791866C0B6AA3" modified="2018-07-18" version="1">MNQTLTPTNAASSAVRTTAHTRFDPVPVRALLQRQYALSGKPADSVPEINSYEDFTRLVPVMDGTTYAALAEATFAQNGAVGFYIGGSSGTTNKPKLVLSGTPRLGIAPTDEQRELIGNLRQNGVFQPGDVVANGFMVGLFSILHHGVNRVLEACGASIVPLGTLDESCVESQLNFLAQIGTNVLVGTPGTLVQVAHAVRRTGISVPIKRIAFTGERLGSTKLALLRSVFPGVRVISLYGISEVGFVAIGDEGSGSHKVRENAYLLETDTDGRLLLTCLDPSNPIPVVRYMPGDRITLETTEEGAWIRHIERSNLDFNFMGNLVELRSLRAAVAQTTGVADPLIDVVLYTGEDGRDELTLRVYGVSDDELVQTRQLVASLPELREAAEKNAGRVEVRSAKLEEAVLSGRQKQRQILDYRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H358</accession>
    <name>A0A2S9H358_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">HipA N-terminal domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_1021</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HipA Ser/Thr kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94400">
        <property type="protein sequence ID" value="PRC94400"/>
        <property type="gene ID" value="S2091_1021"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012893">
        <property type="entry name" value="HipA-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017508">
        <property type="entry name" value="HipA_N1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13657">
        <property type="entry name" value="Couple_hipA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07804">
        <property type="entry name" value="HipA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03071">
        <property type="entry name" value="couple_hipA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Couple_hipA" evidence="4">
        <location>
            <begin position="10"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="domain" description="HipA_C" evidence="3">
        <location>
            <begin position="157"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC94400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="449" mass="50379" checksum="A25628A3A6679C4D" modified="2018-07-18" version="1">MGRHSHTQRLIVWLNGLPVGEWDAAPGRNAFGYFDEWIQDDQGRPLSLSLPFTPSNERYRGELVANYFDNLLPDRDLIRKRLAQRFKTGGVEPYQLLSEIGRDCVGAIQLLPPDEEPQNLYQIVGRPLDEPAIAKILRNATSTEPLRFDDDDHDLRLSIAGAQEKSALLFHQNQWLYPGGSTPTTHILKLPLGIVGNMQADMRTSVENEWLCSKIVAAFGLPVAHCDISTFEDQKVLVVERFDRKYSADGKWIVRLPQEDFCQVTGTAPLHKYQADGGPGIINIMDVLLGSDQKIIDRRNFFKTQLIFWLLAAIDGHAKNFSIAHLPGSQYRATPLYDVLSAHPVIGTGQNQYAPQKVKLAMAIRGSKNYYEIAQIQRRHWTKMAQQVGLGNHVAEEIIVEVLAAVNGVVDAMYNLLPVDFPIDVAQSILDGILHQSDKLSAMPPFDQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H380</accession>
    <name>A0A2S9H380_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="12">ABC-type multidrug transport system ATPase and permease component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">S2091_1052</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94431">
        <property type="protein sequence ID" value="PRC94431"/>
        <property type="gene ID" value="S2091_1052"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="PTHR24221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="SSF90123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-1278">Translocase</keyword>
    <keyword evidence="2 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="31"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="67"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="144"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="173"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="256"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="11">
        <location>
            <begin position="32"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="347"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="380"/>
            <end position="387"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PRC94431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="586" mass="64607" checksum="F70AAB18156E79CE" modified="2018-07-18" version="1">MNSEILNMKKNEKWQAVQLLKSAAKIDQSHVWVGIFLLAIAAGLEAMGPLLGKAFIDNYLLPKHADWVWIGGLLLANFLTGCMATWLRYLQLLRLAGVAMRSVRRLREQVYAHVLRLPMSFFDKAITGQLVSRVTNDTEAVKNLYVQVLFVMLDSSIVVLGALAAMAWLDWRLMLIVATLIPAMVVIVWFYQKWSAPAVARARQLRSDLNAQLAESIAGMSVLQASLADGRFAARFGATNQSHYQARIAELRANAWLLRPALDLMNSMLLVVVIYSFSQRTFSGIEVGILYAFVSYIARVVDPLIQITMQFGQIQQAVVSAARVNTLLNESTELYPTSTQKLRSGSVAFHDVSFGYDPAHPVLHNINLQIKAGNFYGVVGHTGSGKSTLLSLLLRFYIAQSGRIELDGLPLAGVSEEEFRLKVGLVPQEPFLLAASVRDNIAMGRELTQAQIEAAARSAHAHGFIQHLSHGYDTELGEGGAKLSTGQKQLLAIARALAGDPVLLLLDEATSHIDSETEQVVQTALAELRGKVTIIAIAHRLSTIRDADQIIVLNHGKLMEQGRHAELMELPQGIYQKLYLLQALEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H389</accession>
    <name>A0A2S9H389_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Lauroyl/myristoyl acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_1062</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94441">
        <property type="protein sequence ID" value="PRC94441"/>
        <property type="gene ID" value="S2091_1062"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009247">
        <property type="term" value="P:glycolipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd07984">
        <property type="entry name" value="LPLAT_LABLAT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004960">
        <property type="entry name" value="LipA_acyltrans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30606">
        <property type="entry name" value="PTHR30606"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03279">
        <property type="entry name" value="Lip_A_acyltrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF026649">
        <property type="entry name" value="MsbB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC94441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="288" mass="32701" checksum="AE99BCF9B1FBDC51" modified="2018-07-18" version="1">MRLLLGLMWCLHFLPLPILGRFGEAIGSIFYWILPSRRHITKTNLRLCFPELSEAERTTIAKQHFQAYARSVFERSILWWSSEQRVRKLIRVEPAVPTELIAAGPVILLCPHFVSLDVAGIGLVLETPICSIYAPQKNAVFDEALKNGRNRFGLVRLLSRAEGVKPIIRAMREGYGFLMLPDMDFGIKDAEFVPFFGIPAATLTAPARIAAATNAKVVPVIATMLPNYQGWRVTVHPAWENFPGDDIVAATQYMNTFLEEQIRLTPAEYFWSHRRFKTRPEGAEDLYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3A8</accession>
    <name>A0A2S9H3A8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Dehydrogenases with different specificities (Related to short-chain alcohol dehydrogenases)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0967</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94346">
        <property type="protein sequence ID" value="PRC94346"/>
        <property type="gene ID" value="S2091_0967"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="266" mass="28704" checksum="D8089DAB591C4EA7" modified="2018-07-18" version="1">MARILITGSAGGIGQMTARVLLEEGHSVVLHARNGERAKEAHEALPDAEAVLVADLRSISETRSMAESANKLGSFDAIIHNAGAMPLTQSISSDGISELFSVNVLAPYILTAMMERVERFIYIGSGAHRASSAHFNDLQWTTRQWNRNDAYAESKLYGVLLTFAVPRFLPNVLANAVSPGWVATRMGGKNATDDLKESPRTQAWLAVSNSSAAKVSGGYFFHFEQGSANEIAYQTDIQDRLLAECRRVSGISFPASPGAISFSKEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3E1</accession>
    <name>A0A2S9H3E1_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">2-dehydro-3-deoxy-phosphogluconate aldolase</fullName>
            <ecNumber evidence="3">4.1.2.14</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_0494</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>2-dehydro-3-deoxy-6-phospho-D-gluconate = D-glyceraldehyde 3-phosphate + pyruvate</text>
            <dbReference type="Rhea" id="RHEA:17089"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:57569"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="4.1.2.14"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the KHG/KDPG aldolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.14" evidence="3"/>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94491">
        <property type="protein sequence ID" value="PRC94491"/>
        <property type="gene ID" value="S2091_0494"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008675">
        <property type="term" value="F:2-dehydro-3-deoxy-phosphogluconate aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00452">
        <property type="entry name" value="KDPG_aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000887">
        <property type="entry name" value="Aldlse_KDPG_KHG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031337">
        <property type="entry name" value="KDPG/KHG_AS_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031338">
        <property type="entry name" value="KDPG/KHG_AS_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30246">
        <property type="entry name" value="PTHR30246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01081">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01182">
        <property type="entry name" value="eda"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00159">
        <property type="entry name" value="ALDOLASE_KDPG_KHG_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00160">
        <property type="entry name" value="ALDOLASE_KDPG_KHG_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000654"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC94491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="214" mass="22054" checksum="B8A780D2109D9DB9" modified="2018-07-18" version="1">MEMQMKMSAILKQLSQVRVLPILVADDVQQAIRCVATLAENGLSAVEITLRTPNAMNVLAEVVKACPEVCVGAGTILTAQQLIEVQDTGAAFGISPGITPTLAHAAADLGLPYFPGVGGASDLMLALEHGFNVVKLFPSDLVGSTKMAKALGGPFPDVRFCLTGGVTLEATPQLLQQSNVLCVGGSWMCPASLIEANNWAAIAKLAAAAAIAGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3P7</accession>
    <name>A0A2S9H3P7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Dimethylhistidine N-methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_0593</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94590">
        <property type="protein sequence ID" value="PRC94590"/>
        <property type="gene ID" value="S2091_0593"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035094">
        <property type="entry name" value="EgtD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019257">
        <property type="entry name" value="MeTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017804">
        <property type="entry name" value="MeTrfase_EgtD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10017">
        <property type="entry name" value="Methyltransf_33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018005">
        <property type="entry name" value="UCP018005"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03438">
        <property type="entry name" value="egtD_ergothio"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_33" evidence="3">
        <location>
            <begin position="26"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF10017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC94590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="329" mass="36958" checksum="74E3A712F0867B83" modified="2018-07-18" version="1">MTKQMLMPELAVRLKDEFIPVDKILEEISAGLRQPQAHTSPKYLYDALGSKLFEAICELPEYYPTRTEAGIFEAYQDDIACSVGYGSTLIDLGAGNCAKAARLFPALRPEQYVAIDISADFLQIAVAQLQQRYPEVAMMGLCLDFSESLALSQQVRRERRLFFYPGSSIGNYTPSQALQFLRRIHNECQTSSQADSGLLIGVDLIKNENVMNAAYNDALGVTASFNLNLLLHLNRLIGADFDLRQWQHCGFFNSTQNRIEMHLVARQALTATWHGGAREFAQGESIHTENSYKYTQQAFLSLLAEAGFQKSKVWVDPNQWFMLCHAHAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3S7</accession>
    <name>A0A2S9H3S7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_0586</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DoxX family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94583">
        <property type="protein sequence ID" value="PRC94583"/>
        <property type="gene ID" value="S2091_0586"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032808">
        <property type="entry name" value="DoxX"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07681">
        <property type="entry name" value="DoxX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="48"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="75"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="104"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC94583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="130" mass="14093" checksum="C7A53ACB12519E7A" modified="2018-07-18" version="1">MKTLNLQAITMASARIFLSAIFILSGFSKLGAIEPTQVYMQAMGMPSILLWPTIVLEIGAGFLVILGFQTRISAFLLAGFSLITAVVFHNDFTSQVNMIMFLKNISMTGGFLLLAAVGPGLFSIDKRKTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3V2</accession>
    <name>A0A2S9H3V2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Glycosyl hydrolase family 9</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_0662</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94659">
        <property type="protein sequence ID" value="PRC94659"/>
        <property type="gene ID" value="S2091_0662"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008810">
        <property type="term" value="F:cellulase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02850">
        <property type="entry name" value="E_set_Cellulase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004197">
        <property type="entry name" value="Cellulase_Ig-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001701">
        <property type="entry name" value="Glyco_hydro_9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02927">
        <property type="entry name" value="CelD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00759">
        <property type="entry name" value="Glyco_hydro_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="SSF48208"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="SSF81296"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="3" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="1 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CelD_N" evidence="5">
        <location>
            <begin position="3"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC94659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="561" mass="63581" checksum="75169ED73A67009F" modified="2018-07-18" version="1">MKILHNHLGYQRDTRKVALIQSSVSLVGKAFTIVDAEKREPVFVGQLTSRGKVAQWRDWQFWEADFSKLQKDGSYFLVVDDVVSPLASQVFKISPYLYGGQIVSDLLHYFKSQRCAGMFDAADRSCLKYGSNERVDVHGGWYDASGDASKYLSHMSYTNFMNPQQTPQVVWNLIDGRAHMPVQSTWLDDRIVDEATHGADFLMRMLDPAGYFYMTVFDRWSKDVEQREICSYTTQQGHKFATYQAGYRQGGGSAIAALARASGLPRDGEYSRASYLVAAERAFAHLEKHNLSYLDDGKENIIDDYCALLAATELYAATAKPLYASAADFRVAKLMKRQSEAGWFWADDAQTRSYFHAAEAGLPYIALLRFMEIFPDAYLFSDSRDCLRRGLQNDILITLHGDGNPFTYPRQYVQMPDKKGQNQFFIPHQNESGYWWQGENARLASLASAAQGAIRYFAGEDIFCASLSTYAQGALDWIFGFNPFDTCMMQGHGRNNPRYEKGMWNAPGGVCNGITSGLENEEDIDFRSPAESVPTHSWRWSEQWIPHGAWLFHALTQQPME</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H404</accession>
    <name>A0A2S9H404_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CAAX protease self-immunity</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0718</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94715">
        <property type="protein sequence ID" value="PRC94715"/>
        <property type="gene ID" value="S2091_0718"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071586">
        <property type="term" value="P:CAAX-box protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003675">
        <property type="entry name" value="Rce1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02517">
        <property type="entry name" value="Rce1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="26"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="69"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="109"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="141"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="173"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="203"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="277"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="305" mass="32879" checksum="D7674982FD8BF311" modified="2018-07-18" version="1">MSVLSDARKAKVRNIFIGPDGLRAGWSVLLFIVIYASIGAATALILNLIVQMMHLPKTSQNIATLKDTYIGQSILVALVVIATAVMARIEKKSFGSYGLGGQRGVPNFFIGVVAGFICLSILVGLLYVSGHLVFDGIALQGISIFSYASLWFGDFMLVAINEEMMIRGYLQNALFRGIGPWPSILVLSLLFTAMHMGNSGENIIGLIGVFVAGIFFCLLRWLSGSLWLGIGFHGAWNWSQSYLYGAPDSGVTAQGHLMITHAVGDIKMSGGTAGPEGSLFANPVVFIGMMVLLWIIRRTKSPTIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4B6</accession>
    <name>A0A2S9H4B6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phage-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0025</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94830">
        <property type="protein sequence ID" value="PRC94830"/>
        <property type="gene ID" value="S2091_0025"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009241">
        <property type="entry name" value="HigB-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05973">
        <property type="entry name" value="Gp49"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="114" mass="12989" checksum="ABAC991BA3DC8B87" modified="2018-07-18" version="1">MEPQTLIVHFYKSDAGTEPVREWLRTLPHAERKIIGEDIKTVQIGWPLGMPLVRKMGAALWEVRITLPGKIARLLFTVVDKRMVLLHGFIKKSKTTPKDDLQTAMNRLKNSKGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H557</accession>
    <name>A0A2S9H557_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">2-hydroxychromene-2-carboxylate isomerase</fullName>
            <ecNumber evidence="1">5.99.1.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_0292</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>2-hydroxychromene-2-carboxylate = (3E)-4-(2-hydroxyphenyl)-2-oxobut-3-enoate</text>
            <dbReference type="Rhea" id="RHEA:27401"/>
            <dbReference type="ChEBI" id="CHEBI:59350"/>
            <dbReference type="ChEBI" id="CHEBI:59353"/>
            <dbReference type="EC" id="5.99.1.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the GST superfamily. NadH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.99.1.4" evidence="1"/>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95097">
        <property type="protein sequence ID" value="PRC95097"/>
        <property type="gene ID" value="S2091_0292"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018845">
        <property type="term" value="F:2-hydroxychromene-2-carboxylate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901170">
        <property type="term" value="P:naphthalene catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03022">
        <property type="entry name" value="DsbA_HCCA_Iso"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001853">
        <property type="entry name" value="DSBA-like_thioredoxin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014440">
        <property type="entry name" value="HCCAis_GSTk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044087">
        <property type="entry name" value="NahD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01323">
        <property type="entry name" value="DSBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006386">
        <property type="entry name" value="HCCAis_GSTk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DSBA" evidence="3">
        <location>
            <begin position="10"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="2">
        <location>
            <position position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR006386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR006386-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC95097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="204" mass="22831" checksum="38E570BF7E43E79B" modified="2018-07-18" version="1">MRAKESRVCEYYFSPVSPWAYFGHQRLLVLAQQHGVKIDMKPIEIGSVFAVSGGVPLAKRAPQRQAYRLQELQRWSDFLAMPIHLQPAFFPVSGDLAAKLLIATQLTHGTEAALNLCTQIMRALWSEQKNIADEATLIELAEQVELDGCALLKSAETASVAAEYQRHTQQAIAANVHGVPWYVFEGQAYWGQDRLEFLERAFAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H596</accession>
    <name>A0A2S9H596_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Threonine aldolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_0306</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the threonine aldolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95111">
        <property type="protein sequence ID" value="PRC95111"/>
        <property type="gene ID" value="S2091_0306"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:cellular amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001597">
        <property type="entry name" value="ArAA_b-elim_lyase/Thr_aldolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023603">
        <property type="entry name" value="Low_specificity_L-TA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48097:SF9">
        <property type="entry name" value="PTHR48097:SF9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01212">
        <property type="entry name" value="Beta_elim_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta_elim_lyase" evidence="4">
        <location>
            <begin position="30"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC95111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="362" mass="40719" checksum="F3732F59CEB5E423" modified="2018-07-18" version="1">MTEAELNQLRKQCHTLLGGHRQHDPAAEFAAMSAYCATHQIEHDTYGEGEFVQTFEQKIATLLGFEAGVFCITGTMTQTLALRLACAERGSSLVALHPTAHILKHENSNYQLLDHFKVQQCGDPYRTWNCADLQAVKDKIGCVLYELPMREIGGQLPSWDELDAIKNYCREQNIHLHMDGARLWEAQAGYGRPFTEITHGFDTIYVSFYKGIGGLGGAMLLGTKEFVAKAKVWMHRQGGSVFRRTPYVVAAAMQFEQRLADLPACFSRTRELVELIKNFPKLKINPATPQCNMFHLYLPVSRERAIEIRNQIAQQHGIWLFNRAATTALADQSYVEWTVGDQMLALTDTQVLAALTLLHAAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5A2</accession>
    <name>A0A2S9H5A2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">FAD binding domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0343</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95148">
        <property type="protein sequence ID" value="PRC95148"/>
        <property type="gene ID" value="S2091_0343"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD_binding_3" evidence="1">
        <location>
            <begin position="18"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC95148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="421" mass="46969" checksum="F6AF69A263D9D2D1" modified="2018-07-18" version="1">MAIENEIDNESKEQMESVEILIIGAGPAGSVAAALLRQQGREVLVLEREQFPRFSIGESLLPQSMEYLEQAGMLRAVVEAGFQFKNGAAFVRNGQYTDFDFRDKHTIGWGTTYQVQRGTFDHILAKEAERFGAQIRYRHEVTMIDLVQEKPVVTVKDPDGKITQIEAGFILDASGFGRILPRLLKLESPSNFPVRGAIFTHIEDRISGEFDRNKIRVTVHPKHCDVWFWTIPFAAGRCSLGVVAETSFLDRYQGTEVERLQAIISEDESLKTLLENAVWDTPARHIVGYSANVASLSGKGYALLGNAGEFLDPVFSSGVTIAFKSASLAAALLQRQFAGEEVDWQAEYGIPLKKGVDTFRAFVESWYAGGFQQIIFHEEHQPEIRRMIASILAGYAWDLTNPMVKETARRLAALEALCTSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5H4</accession>
    <name>A0A2S9H5H4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GGDEF: diguanylate cyclase (GGDEF) domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0435</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95240">
        <property type="protein sequence ID" value="PRC95240"/>
        <property type="gene ID" value="S2091_0435"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01590">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GGDEF" evidence="1">
        <location>
            <begin position="194"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC95240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="319" mass="36340" checksum="72BACF239CECCA08" modified="2018-07-18" version="1">MLIPEKPDNEVSRIDTLRSFNILDTAPEERFDRLTRLAKRIFDVPIALVSLVDVNRQWFKSCMGLSVSETPREISFCGHAILSDEIFTVPDTLADERFFDNPLVTSDPHIRFYAGCPLTVPNGSKLGTLCLIDMTPRDLNEDDRKLLRDLASMAEQEIAAVQMATLDELTLLSNRRGFEVLGQHALNVCKRINKPASILFFDLNKFKKINDTYGHAEGDYALKKFSEILRLIFRDSDVISRLGGDEFVILLTNANYESSSEVIRRLRQKLDEYNKKAERGYDISFSVGQIEYDSEKHASLADLIQEADAAMYVKKHTKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5L4</accession>
    <name>A0A2S9H5L4_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Peptidoglycan-associated protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">pal</name>
        <name evidence="11" type="ORF">S2091_0467</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the Pal lipoprotein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95272">
        <property type="protein sequence ID" value="PRC95272"/>
        <property type="gene ID" value="S2091_0467"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07185">
        <property type="entry name" value="OmpA_C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02204">
        <property type="entry name" value="Pal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006664">
        <property type="entry name" value="OMP_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006665">
        <property type="entry name" value="OmpA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036737">
        <property type="entry name" value="OmpA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039001">
        <property type="entry name" value="Pal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014169">
        <property type="entry name" value="Pal_lipo_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00691">
        <property type="entry name" value="OmpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01021">
        <property type="entry name" value="OMPADOMAIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103088">
        <property type="entry name" value="SSF103088"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02802">
        <property type="entry name" value="Pal_lipo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51123">
        <property type="entry name" value="OMPA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1 7" id="KW-0132">Cell division</keyword>
    <keyword evidence="5 11" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="3 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0564">Palmitate</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015599739" description="Peptidoglycan-associated protein" evidence="9">
        <location>
            <begin position="28"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="domain" description="OmpA-like" evidence="10">
        <location>
            <begin position="60"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC95272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="173" mass="18351" checksum="7C3BB671DFEB0080" modified="2018-07-18" version="1">MNSITSKLVLAMAAAALMSACSTPVKVEEKAPVAEAPAPVVKAPEVRAVQPVVAEIDPLNDPKGVLANRSVYFDFDKYTVKDEATAMLSAHAKYLASHTARKVLVQGNTDERGGREYNLALGQKRAVAVTKSLTTLGASASQIEAVSLGKEKPKATGNNEAAWAENRRADIVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GS59</accession>
    <name>A0A2S9GS59_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_4739</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000061">
        <property type="protein sequence ID" value="PRC90553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90553">
        <property type="protein sequence ID" value="PRC90553"/>
        <property type="gene ID" value="S2091_4739"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025399">
        <property type="entry name" value="DUF4372"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002559">
        <property type="entry name" value="Transposase_11"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01609">
        <property type="entry name" value="DDE_Tnp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14294">
        <property type="entry name" value="DUF4372"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4372" evidence="2">
        <location>
            <begin position="3"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="domain" description="DDE_Tnp_1" evidence="1">
        <location>
            <begin position="124"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC90553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="388" mass="44861" checksum="CE62E2FAD1D1B175" modified="2018-07-18" version="1">MHHGKLVFSQIMTYLPLTTFRRCVAAHRGEHKVKNFSCLDQFFAMAFAQLTYRESLRDIEVNLRAQAHRLYHMGFRCETISRNTLSNANSTRPWQIYADFAQHLIAMARPLYADEPMGIDLDATVYAFDATTIDLCLSVHPWAPFRSTKAAIKLHTLLDLRGSIPSFIHITDGKTHEVNILDDLAIEPGAFYLMDRGYLDFKRLHRLHELNAFFVTRAKSNTKFKRRYSHPVDRASTNLICDQTGELPLYYASKDYPSTLRRVVVKDENGKRVIFLTNNFALKPELIAALYKQRWQVELFFKWIKQHLRIKSFLGTSENAVKTQIWIAVATYVLIAIVKKRLHLPHSLYEILQILSLTMFETTPLNQLLTPLSNLSDGENQPEQMSLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSB0</accession>
    <name>A0A2S9GSB0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">RHS repeat-associated core domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4677</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000044">
        <property type="protein sequence ID" value="PRC90609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90609">
        <property type="protein sequence ID" value="PRC90609"/>
        <property type="gene ID" value="S2091_4677"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022385">
        <property type="entry name" value="Rhs_assc_core"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03696">
        <property type="entry name" value="Rhs_assc_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC90609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="230" mass="22793" checksum="4B3498619989690C" modified="2018-07-18" version="1">MYGKSASGSSLDAETNLHQNYYRDYDPLSGRYIQSDLIGLGSGTSTFGYVGQNPISLSDRSGLCPWCPGAVGAVIGGITAGMSYNASNPNGSTGSLLGAMAAGAAIGAAAYTPAGWGLLGNMLAGAAAGASGDAIGQYLGKKDEAKACGKTFNFYQEWDGLETLTMAGVGAGAAGLGYVAVPYANAMYSSVAPYAGLTSAQQAVVAATVSGVAQEAATVALPTSVGGARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSB9</accession>
    <name>A0A2S9GSB9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Hemolysin activation/secretion protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_4670</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000043">
        <property type="protein sequence ID" value="PRC90619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90619">
        <property type="protein sequence ID" value="PRC90619"/>
        <property type="gene ID" value="S2091_4670"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005565">
        <property type="entry name" value="Hemolysn_activator_HlyB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013686">
        <property type="entry name" value="Polypept-transport_assoc_ShlB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035251">
        <property type="entry name" value="ShlB_POTRA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027282">
        <property type="entry name" value="TPS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08479">
        <property type="entry name" value="POTRA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17287">
        <property type="entry name" value="POTRA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03865">
        <property type="entry name" value="ShlB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029745">
        <property type="entry name" value="FhaC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="POTRA_2" evidence="2">
        <location>
            <begin position="123"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="domain" description="POTRA_3" evidence="3">
        <location>
            <begin position="182"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="domain" description="ShlB" evidence="1">
        <location>
            <begin position="239"/>
            <end position="554"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC90619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="590" mass="65769" checksum="ACFBB8A2FD4A17E6" modified="2018-07-18" version="1">MSFYSNTANQWPTRFANLFGLLTLLACTAPEARSQIIQTPASEEQRRRAQADAEERQRLLREPSVELRTPILPSSETTEILVLPGESPCFTIHQLSLTVSPQLSREAKIAGASELALDPFFFAQEYLQQYKNVCVGKDGLNLIIKRLTNLILQKGYSTTRVGISEQDLSTGVLTLTLVPGLIHSIHFTDSSSYGTWRNAFPTGPGKLLNLRDLEQGLEQMKRVPFQDVDMQIVPTDEAGESDVILNTNRTKAWKLTATLDNSGAKGTGQLQAGGNFSLDNLFGLSDLFNIGINTDADRKGDQRGTNGHNLYYSLPFGYWNYSISASDYDYHQEIAGNNQTFVSSGKSKNAEFKINQLIQRDQTQKNSWQLKIGKRWSRSFIDEAEIDVQKRNITFVELGWIHKHYFGNAQLDLTLANRWGTSWLGGKADLEGRNTDEPTFTYALQTIDATLTAPFQIANQPLRYIGTLRGQTSHSALYLADQFSIGGRYTVRGFDGELTLTAERGFYLRNELDIPIANSGQSAYIGMDFGKVYGSSAQYLIGDKLAGTTLGIRGAYHGFMYDLFSSWPVNKPAQFKTATPSVGFNLTFQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSH6</accession>
    <name>A0A2S9GSH6_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Putative phosphoenolpyruvate synthase regulatory protein</fullName>
            <shortName evidence="5">PEP synthase regulatory protein</shortName>
            <shortName evidence="5">PSRP</shortName>
            <ecNumber evidence="5">2.7.11.33</ecNumber>
            <ecNumber evidence="5">2.7.4.28</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Pyruvate, water dikinase regulatory protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_4617</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>[pyruvate, water dikinase] + ADP = [pyruvate, water dikinase]-phosphate + AMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46020"/>
            <dbReference type="Rhea" id="RHEA-COMP:11425"/>
            <dbReference type="Rhea" id="RHEA-COMP:11426"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43176"/>
            <dbReference type="ChEBI" id="CHEBI:68546"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.33"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>[pyruvate, water dikinase]-phosphate + H(+) + phosphate = [pyruvate, water dikinase] + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:48580"/>
            <dbReference type="Rhea" id="RHEA-COMP:11425"/>
            <dbReference type="Rhea" id="RHEA-COMP:11426"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:43176"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:68546"/>
            <dbReference type="EC" id="2.7.4.28"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.33" evidence="5"/>
    <dbReference type="EC" id="2.7.4.28" evidence="5"/>
    <dbReference type="EMBL" id="PUGF01000039">
        <property type="protein sequence ID" value="PRC90667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90667">
        <property type="protein sequence ID" value="PRC90667"/>
        <property type="gene ID" value="S2091_4617"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016776">
        <property type="term" value="F:phosphotransferase activity, phosphate group as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006470">
        <property type="term" value="P:protein dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01062">
        <property type="entry name" value="PSRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005177">
        <property type="entry name" value="Kinase-pyrophosphorylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026530">
        <property type="entry name" value="PSRP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31756">
        <property type="entry name" value="PTHR31756"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03618">
        <property type="entry name" value="Kinase-PPPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="162"/>
            <end position="169"/>
        </location>
        <ligand>
            <name>ADP</name>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC90667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="283" mass="31642" checksum="229BD3CE00785FEF" modified="2018-07-18" version="1">MTDLPHVPLPLDGHTVFFVSDGTGITAETFGHSVLTQFDLRFKQIRLPFIDNAEKAHDACQKINEAYAERGLRPIVFSTLVKADLAGIIRQAHGLHMDLIQTFVEPLEQELGIKSTHTVGRSHNTADTQAYKNRIEAINYSLAHDDGQSHKNLAIADVILVGVSRSGKTPTSLYLAMQFGIKAANYPLIPEDFERGKLPSALYAFKGKIFGLTIAPERLSEIRNERRPGSKYAALENCRYEVNEAEAMMKRESIRWLSSTAKSIEEISTTILQEMKTDLVTNW</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSK5</accession>
    <name>A0A2S9GSK5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4590</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000038">
        <property type="protein sequence ID" value="PRC90697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90697">
        <property type="protein sequence ID" value="PRC90697"/>
        <property type="gene ID" value="S2091_4590"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC90697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="41" mass="4759" checksum="3ECA80ABBAECE33D" modified="2018-07-18" version="1">MQMYKLIIADLNRENCFVNLSLDGNCCSLDCSLFNFDQRIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSL0</accession>
    <name>A0A2S9GSL0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Post-segregation antitoxin (Ccd killing mechanism protein) encoded by the F plasmid</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4605</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000038">
        <property type="protein sequence ID" value="PRC90712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90712">
        <property type="protein sequence ID" value="PRC90712"/>
        <property type="gene ID" value="S2091_4605"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009956">
        <property type="entry name" value="Post-segregation_anti-tox_CcdA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07362">
        <property type="entry name" value="CcdA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-1277">Toxin-antitoxin system</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="65" mass="7739" checksum="DDAC1BFC93A33483" modified="2018-07-18" version="1">MSPSLLKKHAKELGLNISPLCEQKLREEIRNQKERKWNEQHANFITAYNKNIETEGVALQEWRTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSN7</accession>
    <name>A0A2S9GSN7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative amidotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4549</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000037">
        <property type="protein sequence ID" value="PRC90723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90723">
        <property type="protein sequence ID" value="PRC90723"/>
        <property type="gene ID" value="S2091_4549"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002818">
        <property type="entry name" value="DJ-1/PfpI"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01965">
        <property type="entry name" value="DJ-1_PfpI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DJ-1_PfpI" evidence="1">
        <location>
            <begin position="7"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="226" mass="24395" checksum="B182531E3BF42A2D" modified="2018-07-18" version="1">MQNSIQIGFLLFPRVTQLDLTGPAQILSRVPNAKIHLVWKALEPVITDVGFSINPTTTFTDCPVLDVLCVPGGIGIGDQVGDTDTLEFLRQQAATAKYITSVCNGSLVLGAAGLLNGYKSACHWMWRKYLPLFGAIPISERVVRDRNRISGGGVTAGIDFAFTLVDELAGADVAKILQLGFEYDPQPPFECGSPESAGPDLVERVIALQAERMKSIEPQILHAALF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSR9</accession>
    <name>A0A2S9GSR9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cytochrome B561</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_4564</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000037">
        <property type="protein sequence ID" value="PRC90738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90738">
        <property type="protein sequence ID" value="PRC90738"/>
        <property type="gene ID" value="S2091_4564"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022904">
        <property type="term" value="P:respiratory electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011577">
        <property type="entry name" value="Cyt_b561_bac/Ni-Hgenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016174">
        <property type="entry name" value="Di-haem_cyt_TM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01292">
        <property type="entry name" value="Ni_hydr_CYTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81342">
        <property type="entry name" value="SSF81342"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="18"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="49"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="89"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="141"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="domain" description="Ni_hydr_CYTB" evidence="3">
        <location>
            <begin position="12"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC90738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="186" mass="20882" checksum="3DFEB1C558F25D3D" modified="2018-07-18" version="1">MQTVINQTSAKYTSTAKFLHWLMAIAIICLFAFGFYMSNLPFSPQKLKLMSYHKWAGVTVFILALVRLSWRIMHRPPSLPAHMGRIEQLIAHAGHVMLYLLMLSIPVSGWLMSSAKGFQTVLFGVLPIPDLLSKDRELGHLLLTVHLGLNLVMAAVVIGHVLAALKHHFKDKDDVLIRMLPDSSNM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSS3</accession>
    <name>A0A2S9GSS3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">GGDEF: diguanylate cyclase (GGDEF) domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_4520</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000036">
        <property type="protein sequence ID" value="PRC90772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90772">
        <property type="protein sequence ID" value="PRC90772"/>
        <property type="gene ID" value="S2091_4520"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GGDEF" evidence="3">
        <location>
            <begin position="491"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="433"/>
            <end position="467"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC90772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="622" mass="69093" checksum="88F09D0BE3C05663" modified="2018-07-18" version="1">MVTSNPSKQSPADVARETFRQLSTTRTQPTPEAYKKLYNEIAGITEPIDNSAQLQKNNEELEKILLNLAVSLTLESHEYADIGQRLTVAAEQHKWADYLRGLNEFTEKVFSQIKNIQPQASAATASSKQVVLAAEDSIQTSILKDLLTRTLALALPSLLTTAPELSQESDALAQLLKKAVAEKDFADIGARLKNLCFKIEHLPAPAPSGAAETPISMSLTDDMLIGMLSKLLSQTLGMAVGALLQNEPKLLAATDTLVEEVKAAKSLSEFQRIETRLKDLCYKITLKGDDSSEQLQLLLSLFKLLLENVSSLLDDDNWLHGQVVVIQELIVGEIDHRALLEATKSLKEVIYKQGVLKDSIDQNKISVKQLMNLFVDRLSVFANTTGEYHEKITAYSSKITHNTSPEVINEVLDSLLVDTLHVQSEARQSHQLMVNAQQEVLDAQTRISELEKKLADMSEQVQKDQLTGSLNRRGLDEILEREAARADRRNIQLCFGMLDIDNFKKINDTFGHITGDGALVHLVNIIKKTLRSMDVVARYGGEEFAIIMPETTLKDAAETLVRLQRELTKHFFMAGNEQILITFSAGVAERHPLEGLETLIKRADKAMYEAKNTGKNRVITAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSX2</accession>
    <name>A0A2S9GSX2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4482</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000035">
        <property type="protein sequence ID" value="PRC90819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90819">
        <property type="protein sequence ID" value="PRC90819"/>
        <property type="gene ID" value="S2091_4482"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC90819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="94" mass="11048" checksum="9911FD16B8508824" modified="2018-07-18" version="1">MSHRDEYIAKMKLQLDNLNLSIAQFETKAHAMQLDAQDAYKEGLVKLHIQSKLAIEKFDELKESSDNSWDQLVAETEKVRDAFVDSYHYFKLHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GT96</accession>
    <name>A0A2S9GT96_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Glycosyl transferases related to UDP-glucuronosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4336</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000032">
        <property type="protein sequence ID" value="PRC90935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90935">
        <property type="protein sequence ID" value="PRC90935"/>
        <property type="gene ID" value="S2091_4336"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016758">
        <property type="term" value="F:hexosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008194">
        <property type="term" value="F:UDP-glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03784">
        <property type="entry name" value="GT1_Gtf-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002213">
        <property type="entry name" value="UDP_glucos_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00201">
        <property type="entry name" value="UDPGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC90935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="432" mass="48241" checksum="0810E4657BC2B33A" modified="2018-07-18" version="1">MQPSKIAFFPEAAYGPALNSIGIAQAVAQLGHKVVFLSDPGFVALYQEYGFEAHPVNLSAPMAAEEMAKFWESFINGHIPNFSKSPFDQIDNYVKDCWAAIVDSAKFAQEDLPRVLDKIRPDLICVDNVILFPAIKQYGTPWVRIISCSENEIEDPAIPPHLSGCAMQDSAAHARFRARFNEVIRPLHDDFNAFLASAGEAPYPLGQFFETSPYLNLLLYPEPVKFKRAHPLLSPQFEYLEGCVRQEKPYVVPHFSAHNEAPLIYVSFGSLGAGDVALLKRLIAALATMPYRVLVNVGAYKDQYTELPPNVIVDSWFPQPSVIPLVDLVIHHGGNNSFTECLFFGKPAIIMPFVWDGHDNATRVEETGHGFKLNRHDWTETALISQMEMCLYSPVIQTKLAATSRHMQAQNGPAKAARLLDELLSKEYICYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTB7</accession>
    <name>A0A2S9GTB7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative O-glycosylation ligase, exosortase A-associated</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_4365</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000032">
        <property type="protein sequence ID" value="PRC90964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90964">
        <property type="protein sequence ID" value="PRC90964"/>
        <property type="gene ID" value="S2091_4365"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017528">
        <property type="entry name" value="CHP03097O-antigen_lig-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045979">
        <property type="entry name" value="DUF5935"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007016">
        <property type="entry name" value="O-antigen_ligase-related"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19358">
        <property type="entry name" value="DUF5935"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04932">
        <property type="entry name" value="Wzy_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03097">
        <property type="entry name" value="PEP_O_lig_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0436">Ligase</keyword>
    <keyword evidence="2 3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="43"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="75"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="106"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="129"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="170"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="193"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="239"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="320"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="365"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="domain" description="DUF5935" evidence="4">
        <location>
            <begin position="1"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF19358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC90964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="441" mass="48959" checksum="8027261AA50F2559" modified="2018-07-18" version="1">MRDIALFILIFSILPFVFKKPFIGVLLFTWVSLMNPHRLTYGAAYDFPFAAVIVVVTLISLLVSNQKKNFPVTGLTITLLVFVTWMTLTTFYALEPTRAWAEWSRVMKTMILVAVILLTINTKQEIQALAWTIGLSLGFFGFKGGVFTILSGGSSHVFGPEGSYITDNNALALALVTALPLIWYVQLSVTQKILRYGFIGLTMLTVIAAVGSYSRGALLGGAAMFFFLWLKNRQKIRTGIILLLIVVVIYAVMPAQWFDRMHTIDNYQQDSSALGRINAWGFAINVASANLMGGGFDCFTNRLFVVYAPEPYNQHAAHSIYFQVVGEHGFVGISLFLLFMFLAWRTGTRVLKFCKDREDLKWASDLAAMCQVSIIGYAIGGAFLTLAYYDLYYDIVAVLILLEKLLLSKDSLTSNATAEPEATAITASNVDLTIRVPQQTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTF1</accession>
    <name>A0A2S9GTF1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Prepilin-type N-terminal cleavage/methylation domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4298</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000031">
        <property type="protein sequence ID" value="PRC91002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91002">
        <property type="protein sequence ID" value="PRC91002"/>
        <property type="gene ID" value="S2091_4298"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="147" mass="14895" checksum="EA37CBC74BAA1309" modified="2018-07-18" version="1">MKAAQQGFTLIELMIVIAIIGILAAVAIPQYQQYTKRSYFTEVIQATTPFKLGVEVCVIQQGLALGGAITGCSGGSNGVPANAVASGQVLSINVSDAGVIAATSNSGASVGVQTDYTLSPQLNAVNSSTLIVWTKLTTSGCVGLGLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTF3</accession>
    <name>A0A2S9GTF3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4286</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000031">
        <property type="protein sequence ID" value="PRC90990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90990">
        <property type="protein sequence ID" value="PRC90990"/>
        <property type="gene ID" value="S2091_4286"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC90990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="65" mass="7457" checksum="F6348CEA6681C353" modified="2018-07-18" version="1">MYPDTKRLRHNRIMVSLDDYEHDLINALANYRGESLAVIARQMIMREAVALLTADHADSLSRRSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTM4</accession>
    <name>A0A2S9GTM4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4253</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000030">
        <property type="protein sequence ID" value="PRC91065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91065">
        <property type="protein sequence ID" value="PRC91065"/>
        <property type="gene ID" value="S2091_4253"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030077">
        <property type="term" value="C:plasma membrane light-harvesting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045156">
        <property type="term" value="F:electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019684">
        <property type="term" value="P:photosynthesis, light reaction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.50.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014747">
        <property type="entry name" value="Bac_photo_RC_H_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011033">
        <property type="entry name" value="PRC_barrel-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50346">
        <property type="entry name" value="SSF50346"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="278" mass="31770" checksum="8EC28F759821EEE0" modified="2018-07-18" version="1">MLRSLIDLNEYAIHATDGNIGHVKDFYFDDEGWAIRYFIVDTGSWLLSRKVLISPIAIGKPNWAEKTLPVLITKEQVKNSPDIDTEKPVSRQHENHYLGYYGYPIYWGGAGLWGAGIYPDMMMPGYLGDNTSTNTLPQEAVINGSRPEEVERHQNSGSHLRSCKAVIGYHIHASDGDIGHVSGMLVDDETWAIRYFIVDTSNWWLGHQVLIAPLWVEEVRWLDRTVTVNLTRQEVKDAAPYDIAVELGREQEVDIHQHYGRAGYWEHEESNKDVELYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTN0</accession>
    <name>A0A2S9GTN0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4175</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000029">
        <property type="protein sequence ID" value="PRC91079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91079">
        <property type="protein sequence ID" value="PRC91079"/>
        <property type="gene ID" value="S2091_4175"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="41" mass="4758" checksum="E19A575E18AB9D95" modified="2018-07-18" version="1">MKFLIYATKLTEFQHYSYTIQTQASTENGCRSQNKALQSAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTV1</accession>
    <name>A0A2S9GTV1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">FCD domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_4158</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000028">
        <property type="protein sequence ID" value="PRC91157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91157">
        <property type="protein sequence ID" value="PRC91157"/>
        <property type="gene ID" value="S2091_4158"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011711">
        <property type="entry name" value="GntR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008920">
        <property type="entry name" value="TF_FadR/GntR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07729">
        <property type="entry name" value="FCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00392">
        <property type="entry name" value="GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00895">
        <property type="entry name" value="FCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48008">
        <property type="entry name" value="SSF48008"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50949">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="5">
        <location>
            <begin position="26"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC91157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="327" mass="36889" checksum="CCD9920BE649441B" modified="2018-07-18" version="1">MKEKPALLPKSDTPTEARPNTAKPLRQRHVELAQRVYEVAINAGLNAGDRMPEQLLAIQCNVSRTPIRRALQLLAEQGIATIDPDGGYRMSNISDTSTGQISDLPQTEEDELFKAILDDLAARRIPTSQTLAALQRRYEASRLTVQNTLQRLLEEQFVERAAGQRWLFKPMVVGSEATAQSYEFRILMEPAALLSPGFKADPVTLAGMRQSLEALEQIAEENFDIQLAERLDYEFHIMIARACSNPFFQDALLNHHLRRRNVTAGGGTNIFRMRQSVRELLHIIEQIERNQMELAADLMRAHLRLLSFGRPRVVGRSIPPMPQTMSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTV4</accession>
    <name>A0A2S9GTV4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Arabinose-binding domain of AraC transcription regulator, N-term</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_4144</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000028">
        <property type="protein sequence ID" value="PRC91143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91143">
        <property type="protein sequence ID" value="PRC91143"/>
        <property type="gene ID" value="S2091_4144"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032687">
        <property type="entry name" value="AraC-type_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020449">
        <property type="entry name" value="Tscrpt_reg_HTH_AraC-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12625">
        <property type="entry name" value="Arabinose_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00032">
        <property type="entry name" value="HTHARAC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="4">
        <location>
            <begin position="243"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC91143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="347" mass="38511" checksum="47F5797F8DB4095E" modified="2018-07-18" version="1">MAIAKPEAQLPASETTTIGSYCLVIAKALESCGVDSARVFRAVGIPIELSTDPLSRLPTETLTKLYRACVEVTNNPYFGLIVAKLIQANNLHALGYALASSSTLMDFCQRLERYFRLVSQAARVSISTVDDKVFLRCELLTEVCGETEDAFFGFLVLTMRSLYKPTFNPIRVELCHAMPLEGAGPYEALCCSPVTFSNKVGLLVFNKADLEQQLDGSCPELAQMNDHIATQYLARIDKGDVVTRVIQKIIEFLPSGECSREKVADALCMSPATMQRKLSLRDAKFQQLLDDTRKELACSYVQQPSRSMTEITFLLGFTDSSNFTRAFKRWTGTSPTHFKSSMSVEEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GU12</accession>
    <name>A0A2S9GU12_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">FAD/FMN-containing dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_4086</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000027">
        <property type="protein sequence ID" value="PRC91191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91191">
        <property type="protein sequence ID" value="PRC91191"/>
        <property type="gene ID" value="S2091_4086"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.45.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016167">
        <property type="entry name" value="FAD-bd_PCMH_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016164">
        <property type="entry name" value="FAD-linked_Oxase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004113">
        <property type="entry name" value="FAD-linked_oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016171">
        <property type="entry name" value="Vanillyl_alc_oxidase_C-sub2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02913">
        <property type="entry name" value="FAD-oxidase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55103">
        <property type="entry name" value="SSF55103"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="SSF56176"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0274">FAD</keyword>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="2">
        <location>
            <begin position="35"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="473" mass="51073" checksum="8F74FD5A484550A4" modified="2018-07-18" version="1">MKHFIDQCRQLIGSTHVLTDSSDMTSYLTDYRQRYIGTAAAILKPANTEQVAEIVKLCAQHRIAITPQGGNTGLVLGSVPDQTGRSIVLSLLRLNQIRHIDDINNTITVEAGCILQQVQNAANSVDRLFPLSLASEGSCTIGGNLSSNAGGTAVLHYGNCRALCLGLEVVTPQGDIWNGLRALRKDNSGYDLRDVYIGAEGTLGVITAAVLQLFPKPASQLTAFVAINSVEAALALLNLARSNSKDTVLSAFEIMSSYSLALVKQHFPELKQPALKEHPYYVLIEFSSQDSEAANCAALENLMTIALDTGTAQDAVLATSLAQSNTLWQLRESISSAQAAEGKNIKHDISLPISQIGTFIQQTDALLQQKFNGCRMVTFGHLGDGNLHYNVSAPKNSSIDDFLAQQNAINRVVYDSVAQFSGSISAEHGLGAQKRDEILRYKSPVEMQLMRSIKQALDPLNIMNPGKVVQPLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GU49</accession>
    <name>A0A2S9GU49_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Bacterial nucleoid DNA-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_4081</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the bacterial histone-like protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000027">
        <property type="protein sequence ID" value="PRC91186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91186">
        <property type="protein sequence ID" value="PRC91186"/>
        <property type="gene ID" value="S2091_4081"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000119">
        <property type="entry name" value="Hist_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020816">
        <property type="entry name" value="Histone-like_DNA-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010992">
        <property type="entry name" value="IHF-like_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33175">
        <property type="entry name" value="PTHR33175"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00216">
        <property type="entry name" value="Bac_DNA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01727">
        <property type="entry name" value="DNABINDINGHU"/>
    </dbReference>
    <dbReference type="SMART" id="SM00411">
        <property type="entry name" value="BHL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47729">
        <property type="entry name" value="SSF47729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00045">
        <property type="entry name" value="HISTONE_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC91186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="90" mass="9460" checksum="FFD8B70321215443" modified="2018-07-18" version="1">MNKTELIEHIAKTADISKAAATRSLDAMIGAVKVTLKKNGTVTLVGFGTFSVGKRAARVGRNPRTGEAIKIKAAKVPKFKPGKGLKDAVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUA4</accession>
    <name>A0A2S9GUA4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3955</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000025">
        <property type="protein sequence ID" value="PRC91284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91284">
        <property type="protein sequence ID" value="PRC91284"/>
        <property type="gene ID" value="S2091_3955"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01047">
        <property type="entry name" value="MarR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00598">
        <property type="entry name" value="HTHMARR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00347">
        <property type="entry name" value="HTH_MARR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50995">
        <property type="entry name" value="HTH_MARR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="1">
        <location>
            <begin position="29"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="166" mass="18899" checksum="134C00A2544208E0" modified="2018-07-18" version="1">MSNTNTSNSNSPEHTGLIEFYKPPDYKPEETVGFMVRCLHMSLLKMIDIEMQQHDLTAMQWRPLLYISTGKVVTAAALAKETNMDTGATTRMLDRLQLKGLLLRKRCDQDRRVVHLALTEEGERICQKIPTGLCKVMNHHLKGFNQAELDTLKGFLERMLLNGLTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUD2</accession>
    <name>A0A2S9GUD2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Sortase and related acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3984</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000025">
        <property type="protein sequence ID" value="PRC91313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91313">
        <property type="protein sequence ID" value="PRC91313"/>
        <property type="gene ID" value="S2091_3984"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="2"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="168" mass="18752" checksum="2233A91FCD5BCEAF" modified="2018-07-18" version="1">MPLHRIAVQQDLADIVAIYNSTVASRQVTADVEEVSVASRQAWFDEHSPEKRPLWVLELDHGQGKQILGWLSFSNFYGRAAYAGTAELSIYLHPDARGKGWGTYCLKLAEAHAPLVGVHTLLGFIFGHNTPSLRLFEKFGFQKWAELPKVANLDGIERDLIILGKRVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUD3</accession>
    <name>A0A2S9GUD3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">HolB: DNA polymerase III, delta' subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_3982</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000025">
        <property type="protein sequence ID" value="PRC91311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91311">
        <property type="protein sequence ID" value="PRC91311"/>
        <property type="gene ID" value="S2091_3982"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004622">
        <property type="entry name" value="DNA_pol_HolB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00678">
        <property type="entry name" value="holB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0235">DNA replication</keyword>
    <keyword evidence="3" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="1" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC91311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="343" mass="38802" checksum="4706E3B4BC399E1D" modified="2018-07-18" version="1">MSRSLYPWQHQAWAQLQQMQGRWPHAILLHGPEGIGKTQFAEWLAQSLLCESPEPDGQACGTCISCGWFGQYSHPDFRRLRPEILEDAVESDGEDTAKTSKATKAPSKEIVINQVRSLSDFMTLSTHRQGRRVIVIYPADAMNVAAANALLKSLEEPGPNTVFILVTCNVDSLLPTMVSRCRQFALTLPSSEQAMSWLLQQEIKHPDQFLAEQGGAPLAAYAASQSESHEQQHEFLLQLQRPDLDGALKIADKLQKTSIPLLLSWMQRWLYDVFSYKLTGKIRYYPRYYKEIDVLALSITIPALLTLLYSNMQRRAVAEHPLSAKLLIEEMLLDYIALCKKRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUJ4</accession>
    <name>A0A2S9GUJ4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NUDIX domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_3947</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the Nudix hydrolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000024">
        <property type="protein sequence ID" value="PRC91402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91402">
        <property type="protein sequence ID" value="PRC91402"/>
        <property type="gene ID" value="S2091_3947"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020476">
        <property type="entry name" value="Nudix_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00502">
        <property type="entry name" value="NUDIXFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="3">
        <location>
            <begin position="15"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC91402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="143" mass="15927" checksum="CBDCD8013EFC0548" modified="2018-07-18" version="1">MESKLINKSAIKPAPIDVAVGILIKPTGEVLMAQRPVGKPYAGYWEFPGGKVETNEAILSALVREFQEELGIEINPDQAQPWCGCDYVYPHAHVRLHFYLCRDWHGEPRGLEGQQLAWQGGAIDVQPILPATIPLLEWLLQAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUM5</accession>
    <name>A0A2S9GUM5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3828</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000023">
        <property type="protein sequence ID" value="PRC91413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91413">
        <property type="protein sequence ID" value="PRC91413"/>
        <property type="gene ID" value="S2091_3828"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="63" mass="6787" checksum="2D7DFB5690505B44" modified="2018-07-18" version="1">MPLAKGSNKAVVSNNIKMLVDEWKESGSIGNSHPKTKRKAVKQAVAIALTKAGKSNKERALKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUP6</accession>
    <name>A0A2S9GUP6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Efflux transporter, RND family, MFP subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_3848</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000023">
        <property type="protein sequence ID" value="PRC91433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91433">
        <property type="protein sequence ID" value="PRC91433"/>
        <property type="gene ID" value="S2091_3848"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006143">
        <property type="entry name" value="RND_pump_MFP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01730">
        <property type="entry name" value="RND_mfp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="30"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="domain" description="HlyD_D23" evidence="4">
        <location>
            <begin position="91"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC91433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="415" mass="44809" checksum="29C9B6F5EF63A03E" modified="2018-07-18" version="1">MSEETNEHAASDQQQPNNTLKSRKHKRTKMIIWIASVILLAVVLLLLIRHFNNAKKVKPPPPGIAITTTTATKGDIGIYLTAIGTVTPIYTASITSQVNGLVIAVHFKEGQLINKGDTLIDIDPRLYTATLLQAQGTLERDENLLAQARMDLDRYRKAWIGEAVSKQVLDDQEKLVLQDQGIVKIDQGMVQYDQLQVDFCHITAPIKGRIGLRLVDPGNVVQSAATLTLAVVTQINPITVIFTIPEDDLAQVQARLRVHAKLKVDAFERTAQKIIASGELLTLDNQIDTTTGTIKARAVFDNKGDTLFPNQFINTRLLVNTIQGATLIPASAIQQNGQASFVYVIQNKIAFMRSVTPGVTNAGSTQVTGLNPGEVVANSSFDKLQDKIAVTLPVPAAAPVVPKPAAAATPGSSAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUQ0</accession>
    <name>A0A2S9GUQ0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">AcrB/AcrD/AcrF family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3849</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000023">
        <property type="protein sequence ID" value="PRC91434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91434">
        <property type="protein sequence ID" value="PRC91434"/>
        <property type="gene ID" value="S2091_3849"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2090.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027463">
        <property type="entry name" value="AcrB_DN_DC_subdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001036">
        <property type="entry name" value="Acrflvin-R"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32063">
        <property type="entry name" value="PTHR32063"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00873">
        <property type="entry name" value="ACR_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00702">
        <property type="entry name" value="ACRIFLAVINRP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82714">
        <property type="entry name" value="SSF82714"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="319"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="343"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="414"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="446"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="505"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="909"/>
            <end position="926"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="959"/>
            <end position="984"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1004"/>
            <end position="1025"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1037"/>
            <end position="1063"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1073"/>
            <end position="1102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="1102" mass="117887" checksum="9B66D33EEF18B365" modified="2018-07-18" version="1">MVAILLVGLVGYTQLPVSALPEVDYPTIQVLTFYPGASPDVIATTVTAPLERQFGELQGLSQMTSTSSGGTSVIVMKFNLALSIDVAEEEVQSGINAAQSFLPSNLPSPPVYSKTNPADAPVLTFAVTSSSMPLSQVEDLVDTRLAPKISQINGVGLVTISGGQKPAVRIQANPVALSSYGINLEDLRTALTQASVNAAKGNFDGPRQDYQINANDQLVTSKDYKKVVVAYRNGAPVMLTDVAQIVDGIENNNQAAWMNLTPAVIVNVQRQPGANTINVIKGIKTLMGQLQDNLPTGIKVTTLTDLTTPIEASVSDVEFELMLTVALVVLVIFLFLRNVYATIIPSVAVPLSLVGTFAAMYLLGYSLDNLSLMALTISTGFVVDDAIVMIENISRYIEAGDSPMDAALKGAEQIGFTIMSLTVSLIAVLIPLLFMGDVVGRLFREFAVTLAVTIVVSAVVSLTLTPMMSARILRRIPKEQQGRFYQASEQVFERMIAFYGRTLKFVLGYQTITLLIALATLLLTCFLYVIIPKGFFPVQDTGVIQGISQASPTIGSASMAIKQQELAKVILADPAVASLSSFIGADGTNITTNSGRMSINLKPLDQRSMSASDVIRRLKKSLEKVAGIQLYMQPVQNITLDDRVSRTQYQFTLEDPDPVELNLWANRFIGQLSKLPELEDVASDQQMGGLAVYLDIDRVTASRLGIAPATIDNTLYDAFGQRQINTMYTQINQYHVVLEAQPQFQLDPDMLNHLYIQANSSSGTSGSGASSSFSSTTSATAGSNALTTTALYTPAANTLTAPANALSPVSSQSSTGTGSVGRANSVMSSSIPFSAFSHFVKTSESLSITHQGQFPSITVSFNLAPNAALGEALTVIDKVQHDMKMPSSLQAGFQGTAASFRDSLANEPLLILAALVTVYLVLGILYESFIHPITILSTLPSAGVGAFLALILFHQDLSVVAIIGIVLLIGIVKKNGIMMVDFALEGERKEGKNATDAIYDACLLRFRPIMMTTMAALLAGLPLALGSGFGSELRRPLGIAMVGGLLLSQGFTLYTTPVIYIFFDKLAKRFTKKGDEKGADDTKPVTQPEQKPEAKPEPESNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUV4</accession>
    <name>A0A2S9GUV4_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ATP-dependent Clp protease proteolytic subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3772</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the peptidase S14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000022">
        <property type="protein sequence ID" value="PRC91494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91494">
        <property type="protein sequence ID" value="PRC91494"/>
        <property type="gene ID" value="S2091_3772"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07017">
        <property type="entry name" value="S14_ClpP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001907">
        <property type="entry name" value="ClpP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023562">
        <property type="entry name" value="ClpP/TepA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10381">
        <property type="entry name" value="PTHR10381"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00574">
        <property type="entry name" value="CLP_protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00127">
        <property type="entry name" value="CLPPROTEASEP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="192" mass="21132" checksum="EA4DD2A30777679C" modified="2018-07-18" version="1">MEEPVETTAPQRDAFLEEKAFKSRTVLLFGQINDVVARDVVRQLIAMSGESREPINFLVCSPGGHVESGDVIHDVIRFIDAPVNMIGSGWVGSAAVNVFLSVPKKRRFCLQNTRFLIHQPSGGVGGQASDIAIQAREIIRVRERIGALIAKETGQKPEKVMLDIERDFWMSAPEAIEYGLVSKSIVSAKEIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUZ4</accession>
    <name>A0A2S9GUZ4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Pirin-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_3817</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the pirin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000022">
        <property type="protein sequence ID" value="PRC91539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91539">
        <property type="protein sequence ID" value="PRC91539"/>
        <property type="gene ID" value="S2091_3817"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012093">
        <property type="entry name" value="Pirin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008778">
        <property type="entry name" value="Pirin_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003829">
        <property type="entry name" value="Pirin_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13903">
        <property type="entry name" value="PTHR13903"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02678">
        <property type="entry name" value="Pirin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05726">
        <property type="entry name" value="Pirin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006232">
        <property type="entry name" value="Pirin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pirin" evidence="3">
        <location>
            <begin position="33"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="domain" description="Pirin_C" evidence="4">
        <location>
            <begin position="189"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003457"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF05726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC91539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="296" mass="32377" checksum="58755DCA4C193E5E" modified="2018-07-18" version="1">MDTQNTQLTTQVRSLQREITGLSTSDGAGVKLLRSLGSGPHARLDPFLMLDEFSSNNPDDYVAGFPSHPHRGFDTVTYLLDGHMRHEDHMGNVGHIKSGGVQWMSAGRGVIHSEMPQQEQGRMRGFQLWINLPAREKMKPAGYQDIQPEQIPVIHTVAGGFVKVIAGSITVEGTTALGPIQGVTTEPVYLDVMLSPNSQLSFDVAELHHAFVYVYEGQLQIGERSVKNHSAGILSEGGKIEVRSLEQETRFLVLAGKPIGEPVVQYGPFVMNTRAEVEQAVSDYQNGILTHQPAVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GV51</accession>
    <name>A0A2S9GV51_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3814</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000022">
        <property type="protein sequence ID" value="PRC91536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91536">
        <property type="protein sequence ID" value="PRC91536"/>
        <property type="gene ID" value="S2091_3814"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015392792" evidence="1">
        <location>
            <begin position="26"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="169" mass="18688" checksum="1BF450233B093D08" modified="2018-07-18" version="1">MINNVVKKMLGFILLGLCLNPVAQADTILGMDVIESQPLNEAWLDSGFLSYHFDRDKGLNGDNYGLGAEYRFSTVNAVTVGRFYNSDREYSNYAGLYYQPLAIGPFRLGVVAGGFNGYPKMKDGGWFLAAIPMASAEWGRVGLNIAIVPSYKDRLYGAISLQLKIKVWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GV99</accession>
    <name>A0A2S9GV99_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3702</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000021">
        <property type="protein sequence ID" value="PRC91586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91586">
        <property type="protein sequence ID" value="PRC91586"/>
        <property type="gene ID" value="S2091_3702"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016831">
        <property type="term" value="F:carboxy-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:cellular amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016105">
        <property type="entry name" value="Pyr-dep_his/arg-deCO2ase_sand"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="89" mass="9855" checksum="1C84A89FA4B443AC" modified="2018-07-18" version="1">METIKVGIREFRADLAEYIAASIPVAVTRHGQTVGYFIPTHGQVDADIAALKKASKTLDQMLAEKSINVDAVVNEFKAIRKKTRVKQNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVS2</accession>
    <name>A0A2S9GVS2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3553</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000019">
        <property type="protein sequence ID" value="PRC91798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91798">
        <property type="protein sequence ID" value="PRC91798"/>
        <property type="gene ID" value="S2091_3553"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="43" mass="5055" checksum="FB9D42CA7548AD61" modified="2018-07-18" version="1">MMVFYLANYLRWLSLRVLAPTSNINLTPSYKQRLIESPTLNLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GW16</accession>
    <name>A0A2S9GW16_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">L,D-transpeptidase catalytic domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_3444</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the YkuD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000018">
        <property type="protein sequence ID" value="PRC91888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91888">
        <property type="protein sequence ID" value="PRC91888"/>
        <property type="gene ID" value="S2091_3444"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071972">
        <property type="term" value="F:peptidoglycan L,D-transpeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd16913">
        <property type="entry name" value="YkuD_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005490">
        <property type="entry name" value="LD_TPept_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038063">
        <property type="entry name" value="Transpep_catalytic_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03734">
        <property type="entry name" value="YkuD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141523">
        <property type="entry name" value="SSF141523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015531433" evidence="4">
        <location>
            <begin position="37"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="domain" description="YkuD" evidence="5">
        <location>
            <begin position="163"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC91888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="425" mass="47266" checksum="AAD9B04618634CFF" modified="2018-07-18" version="1">MRSFVFKSSDQVMSNKLNSAKFALLAVSCCAFVCVAAAVPAKPAPTRPTAVAMPASALTPDPDAMLIEVYKLLAQNQLNSAQALADKLVEAYPTFRLGHLVRGDLLMMHSFPVSTFGAATNAPPDKLKELRDEARARIKSLSERPNPELIPRAILQLRDDQKHVLVVDAKRSRLYVYENQAGHLKFISDYYITQGKLGVEKSKAGDQKTPLGVYYITSHVPGAKLSDFYGSGALPINYPNEWDKVNGRSGSGIWLHGTPSNSFSRPPLDSDGCLVLTNPDLKKLSETVEIGKTPVVISEQVEFITLSKWNAERDLATKLINDWRLDVESKSSKRWLSNYSSSFKNAQGESLPVWFDKQQILFAGAADISIKLSDVTVFNYPGKGNMLVSTFTQESRYGKNRNVTRKRQYWAKEANRWKIIFEGVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GW22</accession>
    <name>A0A2S9GW22_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA-binding protein Hfq</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">hfq</name>
        <name evidence="2" type="ORF">S2091_3466</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homohexamer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the Hfq family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000018">
        <property type="protein sequence ID" value="PRC91910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91910">
        <property type="protein sequence ID" value="PRC91910"/>
        <property type="gene ID" value="S2091_3466"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01716">
        <property type="entry name" value="Hfq"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00436">
        <property type="entry name" value="Hfq"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005001">
        <property type="entry name" value="Hfq"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34772">
        <property type="entry name" value="PTHR34772"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17209">
        <property type="entry name" value="Hfq"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="SSF50182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02383">
        <property type="entry name" value="Hfq"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="1" id="KW-0346">Stress response</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="78" mass="8801" checksum="7027897BA5E5FAC5" modified="2018-07-18" version="1">MSNKGQLLQDPFLNALRKEHIPVSIYLVNGIKLQGHIESFDQYVVLLRNTVTQMVYKHAISTVVPARAVNLPTESEPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GW69</accession>
    <name>A0A2S9GW69_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Sarcosine oxidase delta subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3311</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000017">
        <property type="protein sequence ID" value="PRC91969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91969">
        <property type="protein sequence ID" value="PRC91969"/>
        <property type="gene ID" value="S2091_3311"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008115">
        <property type="term" value="F:sarcosine oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046653">
        <property type="term" value="P:tetrahydrofolate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2270.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006279">
        <property type="entry name" value="SoxD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038561">
        <property type="entry name" value="SoxD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04267">
        <property type="entry name" value="SoxD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="97" mass="11346" checksum="C7204E34A06C44D9" modified="2018-07-18" version="1">MFMFHCPHCNDVREEEEFSYAGEAFIPRPAAPDTATDAEWGDYVFMRKNTKGWHWEQWLHSAGCRKVIAVKRHTFTHEIAGGWTLSEGKRIYLEEQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWB5</accession>
    <name>A0A2S9GWB5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Formaldehyde dehydrogenase, glutathione-independent</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_3333</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000017">
        <property type="protein sequence ID" value="PRC91991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91991">
        <property type="protein sequence ID" value="PRC91991"/>
        <property type="gene ID" value="S2091_3333"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014184">
        <property type="entry name" value="HCHO_DH_non_GSH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02819">
        <property type="entry name" value="fdhA_non_GSH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="ADH_N" evidence="4">
        <location>
            <begin position="35"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="domain" description="ADH_zinc_N" evidence="3">
        <location>
            <begin position="197"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC91991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="400" mass="42217" checksum="5AAF338CB27FA786" modified="2018-07-18" version="1">MSENRGVVYIESGRVEVQSIPFPKLVSPKGRKLGHGVILKVVSTNICGSDQHMVRGRTTASAGLVLGHEITGEVIELGSDVETLKLGDLVSVPFNVACGRCRTCKEQNTGVCLTVNPARAGGAYGYVDMGDWIGGQAEYVMVPYADFNLLAFPDKAHAMEKIRDLTCLSDILPTGFHGAVTAGVGPGATVYIAGAGPVGLAAAASARLLGAAVVIVGDVNPLRLDHARKVGFETVDLSKDASLVDQIEKILGVREVDCAVDCVGFEARGHGHEGSQVEAPATVLNSLMEVTRAAGRIGIPGLYVTDDPGGVDDAARRGSLSVRLGLGWAKSHSFHTGQTPVMKYNRQLMQAILWDRINIAEIVGVQVIALDEAPNGYASFDAGAPKKYVIDPHKMIRRAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWI6</accession>
    <name>A0A2S9GWI6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ABC-type branched-chain amino acid transport systems ATPase component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_3218</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000016">
        <property type="protein sequence ID" value="PRC92083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92083">
        <property type="protein sequence ID" value="PRC92083"/>
        <property type="gene ID" value="S2091_3218"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015658">
        <property type="term" value="F:branched-chain amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030660">
        <property type="entry name" value="ABC_branched_ATPase_LivF/BraG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039137">
        <property type="entry name" value="ABC_branched_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-1278">Translocase</keyword>
    <feature type="domain" description="ABC transporter" evidence="7">
        <location>
            <begin position="6"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="38"/>
            <end position="45"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC92083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="240" mass="25716" checksum="EF3DD851E452113F" modified="2018-07-18" version="1">MTDSVLKISGLKVAYGGIKAVKGIDLEVNQGELVTLIGANGAGKTTTLKAITGTLPSGKVEGDIAYLGKSLTGITPFKLIHQRLAMVPEGRGVFTRMSIHENLMMGAFIREDKAGIEADIEKWFSVFPRLKERSAQLAGTLSGGEQQMLAMARALMSHPKLLLLDEPSMGLSPIMVEKIFEVIRNVSKEGVTILLVEQNAKLALQAAHRGYVMDSGLITISGEAKALLNDPKVQAAYLGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWI7</accession>
    <name>A0A2S9GWI7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Branched-chain amino acid ABC-type transport system permease component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_3215</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000016">
        <property type="protein sequence ID" value="PRC92080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92080">
        <property type="protein sequence ID" value="PRC92080"/>
        <property type="gene ID" value="S2091_3215"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001851">
        <property type="entry name" value="ABC_transp_permease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02653">
        <property type="entry name" value="BPD_transp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="42"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="67"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="100"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="144"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="197"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="223"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="248"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="280"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC92080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="309" mass="32258" checksum="6E4ADB68492B86F5" modified="2018-07-18" version="1">MDTFIQQIINGLVLGSMYALIALGYTMVYGVLNLINFAHGDVLMIGAMVGLSIIRLLDIIAPGLPGMVQLLIAIAGAIPICMLVNVIIERVAYRRLRNAPRLAPLITAIGVSILLQTFSMLIWGRSPISFPQVLSSNPIEIGGAVISPTQATLLVMAAIAMGCLVILVEKTKLGRAMRATAENPRVAGLMGVDTNKVIIATFAIGAALAAIAGVMWGANYSSAQFAMGFVPGLKAFCAAVLGGIGNIYGAMVGGIILGLIESFGAGYIGDLTGGMFGSNYQDIFAFIVLILVLTVRPSGIMGERVADRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWK8</accession>
    <name>A0A2S9GWK8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3244</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000016">
        <property type="protein sequence ID" value="PRC92109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92109">
        <property type="protein sequence ID" value="PRC92109"/>
        <property type="gene ID" value="S2091_3244"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031044">
        <property type="entry name" value="Small_Trp_rich"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04438">
        <property type="entry name" value="small_Trp_rich"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="26"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="73" mass="8894" checksum="75ECC5F56F818E39" modified="2018-07-18" version="1">MILILLTVTLAGLKYFEVSFMANISWWWITGLFFFTFIWFEFIERVLGLDKKKAHKKFDEIHKTRAKKMFDKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWL7</accession>
    <name>A0A2S9GWL7_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 10">Pyruvate dehydrogenase E1 component</fullName>
            <ecNumber evidence="4 10">1.2.4.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">S2091_3254</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 10">Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 10">
            <text>(R)-N(6)-lipoyl-L-lysyl-[dihydrolipoyllysine-residue acetyltransferase] + H(+) + pyruvate = (R)-N(6)-(S(8)-acetyldihydrolipoyl)-L-lysyl-[dihydrolipoyllysine-residue acetyltransferase] + CO2</text>
            <dbReference type="Rhea" id="RHEA:19189"/>
            <dbReference type="Rhea" id="RHEA-COMP:10480"/>
            <dbReference type="Rhea" id="RHEA-COMP:10481"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:83111"/>
            <dbReference type="EC" id="1.2.4.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 10">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer. Part of the PDH complex, consisting of multiple copies of pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.4.1" evidence="4 10"/>
    <dbReference type="EMBL" id="PUGF01000016">
        <property type="protein sequence ID" value="PRC92119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92119">
        <property type="protein sequence ID" value="PRC92119"/>
        <property type="gene ID" value="S2091_3254"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004739">
        <property type="term" value="F:pyruvate dehydrogenase (acetyl-transferring) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02017">
        <property type="entry name" value="TPP_E1_EcPDC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035807">
        <property type="entry name" value="PDC_E1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004660">
        <property type="entry name" value="PDH_E1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041621">
        <property type="entry name" value="PDH_E1_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005474">
        <property type="entry name" value="Transketolase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43825:SF3">
        <property type="entry name" value="PTHR43825:SF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17831">
        <property type="entry name" value="PDH_E1_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00456">
        <property type="entry name" value="Transketolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000156">
        <property type="entry name" value="Pyruvate_dh_E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="SSF52922"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00759">
        <property type="entry name" value="aceE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10 14" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0786">Thiamine pyrophosphate</keyword>
    <feature type="domain" description="TRANSKETOLASE_1" evidence="12">
        <location>
            <begin position="116"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="domain" description="PDH_E1_M" evidence="13">
        <location>
            <begin position="500"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="242"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="272"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="274"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00033635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR000156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000156-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF17831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="PRC92119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="903" mass="100909" checksum="6C575A220A50ECF0" modified="2018-07-18" version="1">MSAQLDHAQLDHVLAQAVNDPDKMETQEWLDALESVIENEGPERAHYLMERMVDLARRRGAHIPFSSNTAYVNTIPADMGEHCPGDLIIEEKLRSMMRWNAMAMVVKANRVDGDLGGHLSSFASLANMLGIGFNHFWHAPTEDHGGDLLYIQGHSSPGIYARAYLEGRLTEEQLLHYRREVDGNGLSSYPHPKLMPDFWQFPTVSMGLGPLMAIYQARFLKYLHARSIADTANRKVWAFCGDGEMDEPESMGAIGMAGREKLDNLVMLVNCNLQRLDGPVRGNGKIIQELESDFRGAGWNVVKVIWGEGWDELLAKDKEGILQRVMMETVDGEYQNYKAKDGAFVRANFFGKHPKLLEMVSKMSDDDIWRLTRGGHDPHKIYAAFKVAQEHKGQPTVLLVKSIKGYGFGKSGEARNTAHNTKKLDDEAIKAMRDRFQLPIADSELAAIPFYKPADDTPEMQYLQARRKALGGYLPQRRQKADEVLIVPELSAFKAVLEPTAEGREISTTAAYVRILTALLRDASLGQRIVPIMVDESRTFGMEGLFRQIGIFSQVGQLYEPVDKDQVMYYREDKAGQILQEGINEAGGMSSWIAAATSYSTNNRVMIPFYTYYSMFGLQRIGDLAWAAGDMRSRGFLIGGTAGRTTLNGEGLQHEDGHSHVLASTIPNCVPYDPTFAHEVAVIIHDGLRRMITNQEDVFYYITLMNENYSHPGIKEGQEQGIIKGLYLLNKNPTQSKHRVQLMGSGTILREVIFGAELLQADWGISADVWSAPSFTLLARDGQDVERWNMLHPSDTPKVAYVTECLQNTEGPIVVATDYMRTFAEQIRGFIPAGRRYKVLGTDGFGRSDSRAKLREFFEVNRYFVVIAALKSLADEGVISASVVSQAISKYGINAEKPNPVTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWS3</accession>
    <name>A0A2S9GWS3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="10">GGDEF: diguanylate cyclase (GGDEF) domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">S2091_3089</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92173">
        <property type="protein sequence ID" value="PRC92173"/>
        <property type="gene ID" value="S2091_3089"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901564">
        <property type="term" value="P:organonitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006796">
        <property type="term" value="P:phosphate-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044238">
        <property type="term" value="P:primary metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd01948">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006189">
        <property type="entry name" value="CHASE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042240">
        <property type="entry name" value="CHASE_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001633">
        <property type="entry name" value="EAL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035919">
        <property type="entry name" value="EAL_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03924">
        <property type="entry name" value="CHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00563">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01079">
        <property type="entry name" value="CHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00052">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141868">
        <property type="entry name" value="SSF141868"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50839">
        <property type="entry name" value="CHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50883">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="domain" description="CHASE" evidence="7">
        <location>
            <begin position="77"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="5">
        <location>
            <begin position="388"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="6">
        <location>
            <begin position="462"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="9">
        <location>
            <begin position="548"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="domain" description="EAL" evidence="8">
        <location>
            <begin position="690"/>
            <end position="944"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC92173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="958" mass="107192" checksum="B6E29E37AFEB2283" modified="2018-07-18" version="1">MDKLLRRVRFSFTVSALLTLFVGLCLTMLVFTAIRKVESDQQKIQFRQNANLRISVIEIGLQDAVEQLVILNQLFRTFGIITREQFHTFTAPILKRYPEIQALSYQRLLRQTDRHNFEMEMRRRNPDFMLTEIVNDQQRRASIRDYYNVIDYLEPSIGNEAALGLDTAYNNDQTLARQRSRDTGNAVSTGLISLAQHKGLHSGFLVLAPVYLQGVPLDGATARERAAIGETSAVFRSDQLINTILRSGGVAEATGMGISIYASAQADPQNLAFQQSGPKPVMESIKLPVGWLFYDNAEPLGHTFTLAGNEWHLEVIQASTPFTVYHHGALYVLLGGLLSSVLAAAYVYKLVLRIATVEHETSERAATLQFANLRLSEDIALSLRTEKSLRLRERVIEVSANAIIICSANAPDYPIEYVNPAFERITGYSADEVLGRSLESLQGNSQDQQNIEEIRAALRDKREGHALLRNYRKDGTGYWNDLFIAPVQDEHGLISHFVVAQYDISAVMKYEAEMEFQASHDTLTGLANRNLLRERLTEAIADAERSGTPLWVVFVDLDRFKFINDTLGHEAGDALLKVLAMRLQSATGEADTVARLGGDEFVLVFPNQTEDAPGLVVLQRIMDSVAQPLMLQDHEFYLTCSMGIAQYPGDGNTAESLIKHADIAMYRAKEMGRNTFQFYTPTMIERTLDRLSIETDLRYALDRDEFVIQYQPQVSLATGRIVGMEVLLRWEHPVLGLIAPTRFIGLAEEMGLIVPIGAWVIRTACIQTKAWHLAGYTDLRVAVNLSPRQFTQKALAQSIADVLAATGLEPHFLELELTESMIMNDVDNAITILRALKQLGVHISIDDFGTGYSSLSYLRRFPIDVLKIDQSFVNELNIDADAAAIVIAIISLAHSLRLKVIAEGVETPEQLAFLRAHGCDQMQGYYFSRPVNAEQFELLLQQESGAIIDDNVLYFGPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWT2</accession>
    <name>A0A2S9GWT2_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Succinate dehydrogenase hydrophobic membrane anchor subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">S2091_3099</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Membrane-anchoring subunit of succinate dehydrogenase (SDH).</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="14">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
        <text evidence="14">The heme is bound between the two transmembrane subunits.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Carbohydrate metabolism; tricarboxylic acid cycle.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92183">
        <property type="protein sequence ID" value="PRC92183"/>
        <property type="gene ID" value="S2091_3099"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00223"/>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000104">
        <property type="term" value="F:succinate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1300.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034804">
        <property type="entry name" value="SQR/QFR_C/D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014312">
        <property type="entry name" value="Succ_DH_anchor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000701">
        <property type="entry name" value="SuccDH_FuR_B_TM-su"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38689">
        <property type="entry name" value="PTHR38689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01127">
        <property type="entry name" value="Sdh_cyt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000169">
        <property type="entry name" value="SDH_D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81343">
        <property type="entry name" value="SSF81343"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02968">
        <property type="entry name" value="succ_dehyd_anc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7 14" id="KW-0349">Heme</keyword>
    <keyword evidence="11 14" id="KW-0408">Iron</keyword>
    <keyword evidence="12 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="9 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 15" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="27"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="65"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="94"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="14">
        <location>
            <position position="77"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <note>ligand shared with second transmembrane subunit</note>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="89"/>
        </location>
        <ligand>
            <name>a ubiquinone</name>
            <dbReference type="ChEBI" id="CHEBI:16389"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00019425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR000169-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR000169-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="PRC92183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="121" mass="13822" checksum="F8A734E6D0C75738" modified="2018-07-18" version="1">MANNNIGPKRLVVGAHYGLKDWLVQRLTAIIMALYTVILLAKFLMANDFSYVGWAGMFAQQWFKLATFAVLMSLFYHAWIGIRDISMDYVKPLVLRLTLQVAAVLWLIGCAGWTVQILWRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWX6</accession>
    <name>A0A2S9GWX6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Negative regulator of sigma E activity</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_3136</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RseB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92220">
        <property type="protein sequence ID" value="PRC92220"/>
        <property type="gene ID" value="S2091_3136"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd16327">
        <property type="entry name" value="RseB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033436">
        <property type="entry name" value="MucB/RseB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038484">
        <property type="entry name" value="MucB/RseB_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033434">
        <property type="entry name" value="MucB/RseB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005588">
        <property type="entry name" value="MucB_RseB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38782">
        <property type="entry name" value="PTHR38782"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03888">
        <property type="entry name" value="MucB_RseB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17188">
        <property type="entry name" value="MucB_RseB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005427">
        <property type="entry name" value="RseB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0574">Periplasm</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015647437" evidence="5">
        <location>
            <begin position="20"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="domain" description="MucB_RseB" evidence="6">
        <location>
            <begin position="24"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="domain" description="MucB_RseB_C" evidence="7">
        <location>
            <begin position="217"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF17188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC92220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="326" mass="36216" checksum="19AE88347F3BF1E3" modified="2018-07-18" version="1">MRTLFLSCILLVTGVPAFADDSVEAQAILQKIQTAAQKTNFAGTFVFQQDNELLSSRITHRFEAGDEQEKIEKLDGRPREYIRHNEDILSYLPDTKTLRPETRQAQDMFPAVLAFNGANLGEHYLFKLAEVARVAGIDCRMVVVEPKDLLRYGYRFCAAIPSNLMLQAQTIGLNNKVLEQIAFSNLTIGSIDENSLKTSYTATSDWKTVRGSVAVSTASGWAVKSLPAGFKKIREVRRLINHHFDGSSIKKSTDLHEVLQLVFSDGLATISVFIEPMNGDHRVGVTQEGATLISGHQQGNFWLTIVGEVPLATIKLISDSIEYKLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWZ3</accession>
    <name>A0A2S9GWZ3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NlpC/P60 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_3155</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C40 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92239">
        <property type="protein sequence ID" value="PRC92239"/>
        <property type="gene ID" value="S2091_3155"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000064">
        <property type="entry name" value="NLP_P60_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00877">
        <property type="entry name" value="NLPC_P60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="SSF54001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51935">
        <property type="entry name" value="NLPC_P60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015777251" evidence="2">
        <location>
            <begin position="25"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="domain" description="NlpC/P60" evidence="3">
        <location>
            <begin position="43"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC92239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="173" mass="19237" checksum="21F4684A5EAF3F89" modified="2018-07-18" version="1">MAIKNTLHNLVIAAAICICIPAWSAEPAPQEQTTVLTKIQEITDRAASLVTKAVDFLGTRYKRGGNNAEQGLDCSGLVRLVFKDAANIDLPRTSLEISRTGEKIEPNELQPGDLVFYNTLKRGFSHVGIYLGDNKFIHSPRPGGQVRIESMELAYWKKRFNGARRINDDEPQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXA6</accession>
    <name>A0A2S9GXA6_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ribonuclease PH</fullName>
            <shortName evidence="4">RNase PH</shortName>
            <ecNumber evidence="4">2.7.7.56</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">tRNA nucleotidyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rph</name>
        <name evidence="7" type="ORF">S2091_3014</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>phosphate + tRNA(n+1) = a ribonucleoside 5'-diphosphate + tRNA(n)</text>
            <dbReference type="Rhea" id="RHEA:10628"/>
            <dbReference type="Rhea" id="RHEA-COMP:17343"/>
            <dbReference type="Rhea" id="RHEA-COMP:17344"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57930"/>
            <dbReference type="ChEBI" id="CHEBI:173114"/>
            <dbReference type="EC" id="2.7.7.56"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homohexameric ring arranged as a trimer of dimers.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the RNase PH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.56" evidence="4"/>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92355">
        <property type="protein sequence ID" value="PRC92355"/>
        <property type="gene ID" value="S2091_3014"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000175">
        <property type="term" value="F:3'-5'-exoribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009022">
        <property type="term" value="F:tRNA nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016075">
        <property type="term" value="P:rRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd11362">
        <property type="entry name" value="RNase_PH_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00564">
        <property type="entry name" value="RNase_PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001247">
        <property type="entry name" value="ExoRNase_PH_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015847">
        <property type="entry name" value="ExoRNase_PH_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036345">
        <property type="entry name" value="ExoRNase_PH_dom2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027408">
        <property type="entry name" value="PNPase/RNase_PH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002381">
        <property type="entry name" value="RNase_PH_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018336">
        <property type="entry name" value="RNase_PH_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01138">
        <property type="entry name" value="RNase_PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03725">
        <property type="entry name" value="RNase_PH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55666">
        <property type="entry name" value="SSF55666"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01966">
        <property type="entry name" value="RNasePH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01277">
        <property type="entry name" value="RIBONUCLEASE_PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="1 4" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 4" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="2 4" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="RNase_PH" evidence="5">
        <location>
            <begin position="15"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="domain" description="RNase_PH_C" evidence="6">
        <location>
            <begin position="162"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Phosphate (substrate) binding" evidence="4">
        <location>
            <begin position="128"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="90"/>
        </location>
        <ligand>
            <name>phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <note>substrate</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00564"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC92355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="242" mass="26676" checksum="37B896807A06B490" modified="2018-07-18" version="1">MIHFQRPSKRNVNALRPVVISRHFTKHAEGSVLVEFGDTKVICTASIEDKVPGFLKGRGQGWLTAEYGMLPRSTNTRMDREAAKGKQSGRTQEIQRLIGRSLRAAFDLEAFGERTLHLDCDVIQADGGTRTAAITGSMVAAYDAFSMLVRQDKILNIPLKKFVAAISVGVYQGVPVLDLDYMEDSECDTDMNVVMTESGQFVEVQGTAEGATFDRPTMNRLLDLAHDGIVDLIALQKQVLDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXA8</accession>
    <name>A0A2S9GXA8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">MaiA: maleylacetoacetate isomerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_2955</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GST superfamily. Zeta family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92296">
        <property type="protein sequence ID" value="PRC92296"/>
        <property type="gene ID" value="S2091_2955"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009072">
        <property type="term" value="P:aromatic amino acid family metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03191">
        <property type="entry name" value="GST_C_Zeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03042">
        <property type="entry name" value="GST_N_Zeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005955">
        <property type="entry name" value="GST_Zeta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034330">
        <property type="entry name" value="GST_Zeta_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034333">
        <property type="entry name" value="GST_Zeta_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13417">
        <property type="entry name" value="GST_N_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="SSF47616"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01262">
        <property type="entry name" value="maiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GST N-terminal" evidence="2">
        <location>
            <begin position="1"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="3">
        <location>
            <begin position="87"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC92296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="212" mass="23744" checksum="82ABDCCF1B29CDA1" modified="2018-07-18" version="1">MKLYSYFRSSASFRVRIVLNLKQLPYDYDAVHLVKQGGAQHTPAYLALNPMGAVPSLDDDGKVLTQSMAMCEYLEELHPQPALLPVDAFERAWVRSVCNLVACDIHPVNNLRILKYLTGPLALTEEQKTAWYHHWIAQGFTALEKLVAQKAGTYCCGDEPSLADAFVVPQIWNAARFACPMEDYPTLRRIYENAMLLPAFEQAAPAAQPDAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXE0</accession>
    <name>A0A2S9GXE0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2762</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92387">
        <property type="protein sequence ID" value="PRC92387"/>
        <property type="gene ID" value="S2091_2762"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="145" mass="16591" checksum="06FE39ECD8EA5F5D" modified="2018-07-18" version="1">MPIGALRHLADIPNEFEIINNMNKQKVLMLPYPTSPVLDGTELRSIGADIYLKIPFDVEGSERIVTVRFINVCAYRQRAESHCTSWHVKDVFDNVSLVVESDWVIELRSVTQLEHKNSFDLNHFITYVNEFGSLEVIAKDVVIES</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXF0</accession>
    <name>A0A2S9GXF0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Putative Zn-dependent protease contains TPR repeat</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_2770</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92395">
        <property type="protein sequence ID" value="PRC92395"/>
        <property type="gene ID" value="S2091_2770"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001915">
        <property type="entry name" value="Peptidase_M48"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01435">
        <property type="entry name" value="Peptidase_M48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2 9" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015393700" evidence="7">
        <location>
            <begin position="33"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M48" evidence="8">
        <location>
            <begin position="104"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC92395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="512" mass="57194" checksum="F5ADD8F9AA65816D" modified="2018-07-18" version="1">MKKTSFKTQLPRLTLVAVLLAGSYLTAPALHAQNLPTLGDTGREDLSPVMERKLGEEIMLGIRADPDYIDDEVAAEYLNDFGSRLLEVHQEARGDANFDFYFFTVRDPMINAFALPGGFIAVHSALVVLAQNESELASVLAHEIGHIAQRHIARMIGNQKQDFLIPIASLILAALTMRSNPDAAMAVAIGGEGLAVQRQLDFSQNAEREADRVGLQILRDGGYDPSGMVAFFERMQSSSRGYSDNFPAFLRTHPMTSERIADIQSRIQSETFKKHIDSPDFQLFRSRIRVLQDESAQALLETKSYFEDQITHAISLKKPYPAAEYGLAFIAFKQNNFKEAQVYLDKARKESGRETGNDVSSLFFTSLQLDILLRSKQNPAALKAAELALQEFPVSRGIGRQYTDALIANQHGEQAITYLRDQTLLYRKDFGLQEQLAKAYAAEGKEALQHLALAESYALSGAISPALDQLDIARRSPDATYYDHAIIDARERDLRERYKDELEALKKQGDKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXP9</accession>
    <name>A0A2S9GXP9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2855</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92480">
        <property type="protein sequence ID" value="PRC92480"/>
        <property type="gene ID" value="S2091_2855"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015419574" evidence="1">
        <location>
            <begin position="29"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="343" mass="38530" checksum="F561F78946F33D99" modified="2018-07-18" version="1">MNFHPNSTLFFRIIILLNAILWSHTVHSADNEAPPRLWQATSVDGKTTFYLLGATHYGLPTEFGSYFDKVVVPAFKTANTLSYEGAGGREPEARPVCDPNVLDENGKKILAEIREKIADLAVREREFVYQQMLLKGVSVPLSEPQRAMLSRAYVRDLDEFELITKYQSDVIILATNSTDSGTAESSSKPLSPQARGNIAFHLRQIRPEISVSDVDSFYGARRAYCSSGPKRIHFFESQINNQELLTSDSFTAKIPRLEFEFSELITNGKYPPNSINQVFDLDHTFTCQRNKEWMQEMAGINDGGIHFYVLGAAHLFNVDHDSAQCDGMLALITKSGMHVQLLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXT2</accession>
    <name>A0A2S9GXT2_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Lipopolysaccharide assembly protein B</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">lapB</name>
        <name evidence="5" type="ORF">S2091_2589</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
            <orientation evidence="2">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the LapB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92534">
        <property type="protein sequence ID" value="PRC92534"/>
        <property type="gene ID" value="S2091_2589"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031235">
        <property type="term" value="C:intrinsic component of the cytoplasmic side of the plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008653">
        <property type="term" value="P:lipopolysaccharide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046890">
        <property type="term" value="P:regulation of lipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00994">
        <property type="entry name" value="LPS_assembly_LapB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030865">
        <property type="entry name" value="LapB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041166">
        <property type="entry name" value="Rubredoxin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18073">
        <property type="entry name" value="Rubredoxin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="2 3" id="KW-0472">Membrane</keyword>
    <keyword evidence="1 2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="2 3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="topological domain" description="Cytoplasmic" evidence="2">
        <location>
            <begin position="23"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="domain" description="Rubredoxin_2" evidence="4">
        <location>
            <begin position="354"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="356"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="359"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="370"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="373"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF18073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC92534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="391" mass="45176" checksum="096CBF7498E24C9A" modified="2018-07-18" version="1">MEFEIWWLLFIPVFFILGWVAARVDIKQLLSESRSLPRGYFKGLNFLLNEQHDKAIDAFIEVLKLDPETVDLHFALGNLFRRRGETERAIRVHQNLLVRPDLPLEQQGQANYELGQDYLKAGLLDRAEETFGLLINSTYSVQARRALLEIYQREKEWMRAIDAAIALQESGAGTRQKEIAQFYCELAQDEILNAHTNVAVEWLEKAHATDRSNVRATILRGDIYLAENQPENALQTWRRVEQQSAPHVSLVAQRIMDVYSSLSRAQEGINVLKNYLEQAPSIDLLEVLYQASLEVEGREAATQIVLEEVRRTPTLLGLDKLLDARMLYVAPDRLQELAMVKNLVHGYAKKLARYQCSHCGFKARQFYWQCPGCNRWETYPPRRTEELNVMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXU1</accession>
    <name>A0A2S9GXU1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative integral membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_2588</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92533">
        <property type="protein sequence ID" value="PRC92533"/>
        <property type="gene ID" value="S2091_2588"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010445">
        <property type="entry name" value="LapA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06305">
        <property type="entry name" value="LapA_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="42"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="domain" description="LapA_dom" evidence="7">
        <location>
            <begin position="22"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="64"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF06305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC92533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="101" mass="11575" checksum="F557C6A793278349" modified="2018-07-18" version="1">MKIISKIITVLLFVIFFGFALNNTESVTLRFFMGYEFPGPLVLMLLIFFIAGIVLGVFAMLPTLFRHRRDLSKHKKNLTAMEQEVTKLQTENSRPPQPDSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXV7</accession>
    <name>A0A2S9GXV7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">MltB: lytic murein transglycosylase B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_2595</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92540">
        <property type="protein sequence ID" value="PRC92540"/>
        <property type="gene ID" value="S2091_2595"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023346">
        <property type="entry name" value="Lysozyme-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011757">
        <property type="entry name" value="Lytic_transglycosylase_MltB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043426">
        <property type="entry name" value="MltB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031304">
        <property type="entry name" value="SLT_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30163">
        <property type="entry name" value="PTHR30163"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30163:SF0">
        <property type="entry name" value="PTHR30163:SF0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13406">
        <property type="entry name" value="SLT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53955">
        <property type="entry name" value="SSF53955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02282">
        <property type="entry name" value="MltB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015416943" evidence="2">
        <location>
            <begin position="29"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="domain" description="SLT_2" evidence="3">
        <location>
            <begin position="49"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR611757-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC92540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="362" mass="40233" checksum="CC22312492796E89" modified="2018-07-18" version="1">MPSTQALPRLAALLITLASLLCSMPVFADDPKTISVNVVDAASIDFNNSKEVNEFIDYMVTRHAFTRAELELVFSKVQFNAQSIQLIKPAPITKPKNWQAYRARFVEPIRIKAGVEFWNKYAEALNRAEKQYGIPAQIIVGIIGVETVFGKNVGKFRVVDVLSTLGFAYPDIANKEARMAYFRGELEQSLLYARESGIDPFSLLGSYAGAIGWPQFMPSSIRQYGVDFDGAGKIDLRNSPEDAIGSVANFLVQHGWETGLPMAFPATITNDRPELMIAKELNATYTLQQLADVAVPTQKNTPTQPLYGLIDLQNGENSTEYWLATHNFFAITKYNRSYFYAMSVIELGKAVCTARNANNPCQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GY03</accession>
    <name>A0A2S9GY03_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">S2091_2643</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92588">
        <property type="protein sequence ID" value="PRC92588"/>
        <property type="gene ID" value="S2091_2643"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011712">
        <property type="entry name" value="Sig_transdc_His_kin_sub3_dim/P"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07730">
        <property type="entry name" value="HisKA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="27"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="9">
        <location>
            <begin position="207"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="8">
        <location>
            <begin position="418"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="272"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC92588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="510" mass="57106" checksum="2484F3030FFF8858" modified="2018-07-18" version="1">MRPESIGKRRVKYKLSLWRNWSIRQRLLLITLLPVTYLFCMLVWHSYWLHSHEVDSEIEERGKIITKVLARSSEYELATGRLSELSLSLDSLVQSEHSIASIDILNVDKKIILHSQSADKEQFELRAFDMPIIKRLIWINVIPAQVDPSLPHETMRSGNSAQIAGYVHVVMSPSDLQRKQKHRFSLELMVAALGLLISGGLAIHLSRTLSASFKTFIEACRAIRKGNYPVQLEVSSGGEIGELQASIKEMALSLQQSTHELENKVVQRTIELENSRNEALKANDEKRKLIQKVQNIVEEERKSIALEVHDELNAALIAARLQAQRIADLAAKIPETPESEEITQHALSIKQITRNLYDNGRALVRRLRPEVLDMLGLQGAVAEMVASYSSTHPSCHFSCEVDGDFSGLDNVSAMSAYRIIQEALSNIIKHADAHQAQVLLQLDADKNTVHVRITDDGKGFVQNDITEGIGLVGIRERVFALGGQIQIESNNSADQPSGTVISIWFDAVRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GY10</accession>
    <name>A0A2S9GY10_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_2601</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92546">
        <property type="protein sequence ID" value="PRC92546"/>
        <property type="gene ID" value="S2091_2601"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="7"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="138"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC92546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="205" mass="22091" checksum="0FBC54852AE8FD15" modified="2018-07-18" version="1">MSSPTIRVLIAEDQALVLGALSALLKLEPDLDIVGMARNGKEALAMAQTLLPDIIMTDIEMPLMTGLELASKLQELALPSKVLIVTTFARTGFLRRALSAGVRGYLLKDAPSETLAAAIRTVHAGGRAIAPELAIESWSGAQDPLNERERQVLRLAGEGKRSAEIAKLIHLSEGTVRNYLSEAISKLNANTRVEAFRLARDAGWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GY64</accession>
    <name>A0A2S9GY64_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2717</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92662">
        <property type="protein sequence ID" value="PRC92662"/>
        <property type="gene ID" value="S2091_2717"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="186" mass="21250" checksum="3FBD87A2D21ACC23" modified="2018-07-18" version="1">MTVVCSKCLEEKPESGFHKNKAAPSGLRLECKACRKSIGMNYRKIPDVAQKSAVRISEWVKKNPESTKAAQRRHAEKNREMRRQYSRLYQKEHRAQDAERSARQRAEIKRATPNWANLDYIAGIYELCALFRRTGLDWHVDHIIPINGKNVVGFHVENNLQILSAIKNISKGNRLNDLDGGCLLPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYN2</accession>
    <name>A0A2S9GYN2_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Probable membrane transporter protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_2565</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92835">
        <property type="protein sequence ID" value="PRC92835"/>
        <property type="gene ID" value="S2091_2565"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002781">
        <property type="entry name" value="TM_pro_TauE-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01925">
        <property type="entry name" value="TauE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="30"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="71"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="103"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="147"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="188"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="212"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC92835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="257" mass="26629" checksum="101C9117C0E183D7" modified="2018-07-18" version="1">MTLSYVISGFVVGILVGLTGVGGGSLMTPLLTLLFGVSPTVAVGTDLAFASITKTAGTFTHKLRGTVNWRIVRLLCFGALPSAVLAAICLKHFGALDKEIGQIIRYTIAGSVLLTVVALLFKGRMLAWLNSHPEKQLQGRSLDAATIIAGAVLGALVTVSSIGAGAIGATLLVMLYPRLTAAEVAGTDIAYAVPLTAIAAIGHWWLGSINWALLFTLLIGSIPGIILGSMAARAVPERVLRVVLASTLTLVAAKLIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYX9</accession>
    <name>A0A2S9GYX9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SPW repeat</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2361</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92944">
        <property type="protein sequence ID" value="PRC92944"/>
        <property type="gene ID" value="S2091_2361"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005530">
        <property type="entry name" value="SPW"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03779">
        <property type="entry name" value="SPW"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="61"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="85"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="117" mass="12918" checksum="AD1239E525CD434A" modified="2018-07-18" version="1">MSLRWQDWVSALLGCWLLVSPWEMGYLLNLDAKGNACGVGAALIIFNLISACRKVDDGQEIVNIVLGIWLILSPYALSFSTEKNLTLNVIAVGSAVIILAAWQMFDAIRMFKSNKLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZ25</accession>
    <name>A0A2S9GZ25_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Pirin-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_2401</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the pirin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92984">
        <property type="protein sequence ID" value="PRC92984"/>
        <property type="gene ID" value="S2091_2401"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012093">
        <property type="entry name" value="Pirin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008778">
        <property type="entry name" value="Pirin_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003829">
        <property type="entry name" value="Pirin_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13903">
        <property type="entry name" value="PTHR13903"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02678">
        <property type="entry name" value="Pirin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05726">
        <property type="entry name" value="Pirin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006232">
        <property type="entry name" value="Pirin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pirin" evidence="4">
        <location>
            <begin position="29"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="domain" description="Pirin_C" evidence="5">
        <location>
            <begin position="185"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="283"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003457"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF05726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC92984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="302" mass="32994" checksum="28A9C5D3E94B3A88" modified="2018-07-18" version="1">MTTTGLSQLSQLSQLLPAHEHDLGGGFIVRRLLPAAVRQSVGPFVFFDHFGPITIEPGKGNNVRPHPHIGLATVTYLFDGAIVHRDSLGTTQQIEPGDINWMTAGSGIVHSEREPEALQGTTYCLHGLQLWVALPIDQEEVAPNFIHTSASQIPALQVDDAEVRVLIGAAFGKISPVATFSNTLYLDIQLPENGTFTLPPLAAEMAVYALESDLTIGENKLFKYSLGVIAPGSSTRIHSTSKTRLIVLGGEPLESKRWIWWNFVSSRKERIDQAAKDWQEQRMGSVAGDPEFIPLPPTKKTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZP1</accession>
    <name>A0A2S9GZP1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2259</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93173">
        <property type="protein sequence ID" value="PRC93173"/>
        <property type="gene ID" value="S2091_2259"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024501">
        <property type="entry name" value="DUF3141"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11339">
        <property type="entry name" value="DUF3141"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="573"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="578"/>
            <end position="592"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="741" mass="82934" checksum="82653174B4B43382" modified="2018-07-18" version="1">MPMLSSDVPIPTLNSLNTSAFDYWTDTAQRTLLFWDALRERGNDYIEHEQSGKPPVLVFDYQIILDARKFTRAANYALAAILPPAGCIPTDLNKRPFVVIDPRAGHGPGIGGFKMDSEIGIALKAGHPCYFVMFFPHPVEGQTIECVTNAERLFLDKVNERHPHAPGKPFVIGNCQGGWALMILAALAPNSVGPILLAGSPISYWAGVEGKNPMRYMGGLLGGTWAASFAGDLGNGKFDGANLVNNFEKLDPGNTHWSKLYGLYANIDTEKERYLEFERWWGGHFLLNKEEMEWISQNLFVGNRLSAGEITIDGETVNLRNIRSPIVVFASWGDNITPPQQALNWIPDLYDSADEIRDNEQTIVYFLHEQIGHLGIFVSSGVANREHSEFASALDLIDVLPPGLYEAIIRDTTPDMPGLSFGDDKHVIRFEPRDVADILALGDGREGEKAFELVRHVAELNQSMYDKFMSPFVKMFSSELTATCLRNLNSARLERSLISDSNPMLKALKPLADMVRAQRKPIAADNPWLKAEQKTAEAIRNSWDSYRDKRDAGYEKLFKAIYESPLVASMSGYNQEEGTRHRSNDEQDEKMRQRRAEHECWFEQGSVETGFLRLLIFVASGNGVIDERPFNGIRRLMLEIGLDKTVSLQQLKATIKQQTFLVRMDEQRALSGLTVLLPKPAERHRALKLARELLELSGPISAEKEGRLQRVAHVLDLDSDVAVSKKKAVRAKSVVPKKVSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZQ7</accession>
    <name>A0A2S9GZQ7_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">Octanoyltransferase</fullName>
            <ecNumber evidence="6 7">2.3.1.181</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Lipoate-protein ligase B</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Lipoyl/octanoyl transferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">lipB</name>
        <name evidence="12" type="ORF">S2091_1952</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 6 7">Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6 7">
            <text>L-lysyl-[protein] + octanoyl-[ACP] = H(+) + holo-[ACP] + N(6)-octanoyl-L-lysyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17665"/>
            <dbReference type="Rhea" id="RHEA-COMP:9636"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="Rhea" id="RHEA-COMP:9752"/>
            <dbReference type="Rhea" id="RHEA-COMP:9928"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78463"/>
            <dbReference type="ChEBI" id="CHEBI:78809"/>
            <dbReference type="EC" id="2.3.1.181"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 6 7">Protein modification; protein lipoylation via endogenous pathway; protein N(6)-(lipoyl)lysine from octanoyl-[acyl-carrier-protein]: step 1/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="6">In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6 7">Belongs to the LipB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.181" evidence="6 7"/>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93214">
        <property type="protein sequence ID" value="PRC93214"/>
        <property type="gene ID" value="S2091_1952"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00538">
        <property type="reaction ID" value="UER00592"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033819">
        <property type="term" value="F:lipoyl(octanoyl) transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009249">
        <property type="term" value="P:protein lipoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16444">
        <property type="entry name" value="LipB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00013">
        <property type="entry name" value="LipB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004143">
        <property type="entry name" value="BPL_LPL_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000544">
        <property type="entry name" value="Octanoyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020605">
        <property type="entry name" value="Octanoyltransferase_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03099">
        <property type="entry name" value="BPL_LplA_LipB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016262">
        <property type="entry name" value="LPLase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00214">
        <property type="entry name" value="lipB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51733">
        <property type="entry name" value="BPL_LPL_CATALYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01313">
        <property type="entry name" value="LIPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6 7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="BPL/LPL catalytic" evidence="11">
        <location>
            <begin position="34"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="6 9">
        <location>
            <begin position="73"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="6 9">
        <location>
            <begin position="147"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="6 9">
        <location>
            <begin position="161"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-thioester intermediate" evidence="6 8">
        <location>
            <position position="179"/>
        </location>
    </feature>
    <feature type="site" description="Lowers pKa of active site Cys" evidence="6 10">
        <location>
            <position position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00024732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR016262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR016262-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR016262-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR016262-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PRC93214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="214" mass="23216" checksum="A9611498FE3EFEC1" modified="2018-07-18" version="1">MPVNNFPISILDRGHEPFATTFAAMRAYTDNRTADSADQLWIVEHDPVYTLGLAADTSHVLNANNIPVVQTDRGGEVTYHGPGQVVIYLLLDLKRQRRQGLVREFVQKIEQAVINTLSTYNLAGARKTGAPGIYMSDGAWAGAKIAALGLKVRASGCTYHGVSLNVAMDLTPFTTINPCGYADLTCVDMRSLGITATLPEVQMTLANQLQHLLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H029</accession>
    <name>A0A2S9H029_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1964</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93226">
        <property type="protein sequence ID" value="PRC93226"/>
        <property type="gene ID" value="S2091_1964"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021484">
        <property type="entry name" value="DUF3137"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11335">
        <property type="entry name" value="DUF3137"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="299" mass="33939" checksum="4111AED8D1E7CA1E" modified="2018-07-18" version="1">MLRKLEEERQVSAFWAKIWMIPVMLIALAAAKFMHSRGETAAMVGMIFVGLIFSAFVYRHFISKVAKDFKEQVLPILLEDVDPSLSYIVDNGIELDEFNEAGLFQHPDRFTGKDLITGNIGQVEVQFSLVHAQEKRVETTTDSDGSTTTQTTYETLFSGLFFIADFNKHFAGRTLVKQKKFDLFNKLFGSPVLLEDPEFNNMFTVYATDQVEARYIMTPSLMEKFKILHSKVGSFQACFSHGRLLMAIEMPQDFFEPLMSKSLTDSVQLQKIVFNLRLITGIVEDLGLNVRIWGAKTGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0F9</accession>
    <name>A0A2S9H0F9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1830</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93443">
        <property type="protein sequence ID" value="PRC93443"/>
        <property type="gene ID" value="S2091_1830"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011747">
        <property type="entry name" value="CHP02241"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010667">
        <property type="entry name" value="Phage_T4_Gp19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38009">
        <property type="entry name" value="PTHR38009"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06841">
        <property type="entry name" value="Phage_T4_gp19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02241">
        <property type="entry name" value="TIGR02241"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="152" mass="17320" checksum="4F1F64DF1C6CB874" modified="2018-07-18" version="1">MADDGTKQSPNVWPLPKFYFRVKWDSNEMSFQEVSGLDIQSEEIKYRSGNSPVFSVIKMPGMKKYGNITMKKGVFKGDNKFWDWLNQIKLNTIKRVPVTISLLDEEGNDTMVWTLTNAWPTKISSTDLKSEGNEVAIESIEIVHEGLTIANK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0H6</accession>
    <name>A0A2S9H0H6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1837</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93450">
        <property type="protein sequence ID" value="PRC93450"/>
        <property type="gene ID" value="S2091_1837"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="1270" mass="144472" checksum="85CFED0F904E2254" modified="2018-07-18" version="1">MKPQLIISDGRSQTQRQLPALNGDYFQLDEMRFEQILAIANEYARLVHFYQIDLSIDGNWQQFFGTDESILMASILAIDTNKLSNQFELRIQGQPQYREWFRDDIVKKIDASYRDVINSPLLFVRLLNQWLTALRVQQSDVAIEVRKLLEGILRGLKWEIQTLCNATPRLLLPYTDGLCSKSFKDLVEWPAPRLRAPASDGNSSSQEQEIGEEKTFTKSEILHNFHAFNQALRMLQNGIKKLLPLSMLSGKHDPAVSLLIGFVSLYQQLQVRLNRFGDKHIDFYYHKVLGMQLQQQRIDSAYLVIKPSPAARSITIAKGTEFTAGVDQDQNDIVYTADEATQLNNARVSSLHSIYFEKHHGETKLLVTKSSYQRSIAVLRPDCEVGEHEKLPPLPLLGAPKPGEHLADGQPTRFGFAIASHTLLMQEGERSIRLLFKFRQNEKYTIDETLKSIAEQLQTQGKREHLNTSSLEESDVFVKLLRSMFRISISTLNGWYVVPEYRPEYYELNSEVPKNCLAIHITLPSSTPAITPYQEKLHAESLQTKTPVIRFEMTQNEYAYPYDILTHWLLEEIDLEINVKACRQLVLHNQIGQVSALAPFMPFGPIPDLSSYLVIGCEEVLGKQLRDVSLDIEWAGLPNALGGFSDYYRGYQTPLKADDVNVKLAVLVDGKWSKAPASVPLFQYETNENGSASNQVNIENRISLKSVVSLYKPTRLTQLPKAGTRLTYTSATMNGMFKISLDAPEGAFGHQEYPQLLTRVLTQNAQTKKIGSMQGLPNPPYTPQISRIVFNYKAFAKINFDQSQSDNPELPQEQFLHLHPLGWEVMRANESKQISLIPKYPAAGNLMIGLQAEQLRGPLSLYFYLREDSLPMTKIHHTGLSWWYLASNKWKRLQQAQILDDSTHGFMTSGIVQLQLPDEINRDNTIMSSDQFWIGVTADYGIERFCSLYAVFAQAIKVSWSPTHGMKPAPILPALSLNKSRSLIVGVDSILQVRASFNGKAEETKQQFRTRASERLLHKNRALTAADYELLILEQFPQVFKVKCFSHLCSDQNPRTRVRPGHLLIVPIPYLNQSVHANQKPTLSGHLIHEIQTYIEKFASADVMISVENPVYEEVQVRCTVKLKTLVNNSRMSGQMSGRYIEQINQAICDYLSPWNDRGLNQHFGWTIQQNNIISFLHDLDYIDEVTGVSLLQISTYGDINDLRFKLTSNAKAERHQKNLTPSYPWSITVPMNEHWIVIVDQFEQKAAKAIGINELKVGSTFIIPSRKEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0H7</accession>
    <name>A0A2S9H0H7_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Phosphatidylglycerophosphatase A</fullName>
            <ecNumber evidence="1">3.1.3.27</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Phosphatidylglycerolphosphate phosphatase A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_1753</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycero-3'-phosphate) + H2O = 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:33751"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:60110"/>
            <dbReference type="ChEBI" id="CHEBI:64716"/>
            <dbReference type="EC" id="3.1.3.27"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="1">Phospholipid metabolism; phosphatidylglycerol biosynthesis; phosphatidylglycerol from CDP-diacylglycerol: step 2/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.27" evidence="1"/>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93366">
        <property type="protein sequence ID" value="PRC93366"/>
        <property type="gene ID" value="S2091_1753"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00084">
        <property type="reaction ID" value="UER00504"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008962">
        <property type="term" value="F:phosphatidylglycerophosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006655">
        <property type="term" value="P:phosphatidylglycerol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009395">
        <property type="term" value="P:phospholipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06971">
        <property type="entry name" value="PgpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026037">
        <property type="entry name" value="PgpA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036681">
        <property type="entry name" value="PgpA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007686">
        <property type="entry name" value="YutG/PgpA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36305">
        <property type="entry name" value="PTHR36305"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04608">
        <property type="entry name" value="PgpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006162">
        <property type="entry name" value="PgpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101307">
        <property type="entry name" value="SSF101307"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="1" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="1" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1 2" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0595">Phospholipid degradation</keyword>
    <keyword evidence="1" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="66"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="104"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="148"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="domain" description="PgpA" evidence="3">
        <location>
            <begin position="25"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR006162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04608"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC93366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="173" mass="19524" checksum="D4FD8CB3CE0F365A" modified="2018-07-18" version="1">MSQDSVNPPQKIKPTAVFMLSDPSHFIAQGFGSGLSPIMPGTAGTLFGWIAFNVLSHRWPTVFTEAHWAWIIVLGFLLGIVVCDRTGRAMGVSDHGSMVWDEIIAMWLVLLFIMPASFSTQCWAFFWFRVFDMTKPPPIAYFDQHIKGGFGVMWDDIVAAFYTLLLFAVWRLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0P5</accession>
    <name>A0A2S9H0P5_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 6">dTDP-4-dehydrorhamnose reductase</fullName>
            <ecNumber evidence="4 6">1.1.1.133</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_1555</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>dTDP-beta-L-rhamnose + NADP(+) = dTDP-4-dehydro-beta-L-rhamnose + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:21796"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57510"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:62830"/>
            <dbReference type="EC" id="1.1.1.133"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="6">Binds 1 Mg(2+) ion per monomer.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 6">Carbohydrate biosynthesis; dTDP-L-rhamnose biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 6">Belongs to the dTDP-4-dehydrorhamnose reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.133" evidence="4 6"/>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93554">
        <property type="protein sequence ID" value="PRC93554"/>
        <property type="gene ID" value="S2091_1555"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00124"/>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008831">
        <property type="term" value="F:dTDP-4-dehydrorhamnose reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019305">
        <property type="term" value="P:dTDP-rhamnose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005913">
        <property type="entry name" value="dTDP_dehydrorham_reduct"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029903">
        <property type="entry name" value="RmlD-like-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10491">
        <property type="entry name" value="PTHR10491"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04321">
        <property type="entry name" value="RmlD_sub_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01214">
        <property type="entry name" value="rmlD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0521">NADP</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RmlD_sub_bind" evidence="7">
        <location>
            <begin position="1"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU364082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC93554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="298" mass="32869" checksum="3D8C180C0D16D0B6" modified="2018-07-18" version="1">MKILLLGKNGQVGWELQRSLAPLGELIALSSQSTEYCGDLLNLDGIAQTIRQINPDIIVNAAAYTAVDKAETDQEHTRKVNALAPALLAEEATRCDALLVHYSTDYVFDGSGDHHWQETDAPHPLSVYGKTKREGEEFILNSGCKHLIFRTSWVYAARGGNFAKTMLRLAQERDQLNVINDQIGAPTGADLLADVTAHCVQQALKTPEAQSLYHLVAGGETTWYDYARFVIESARESGLAIKVAAEAIKPIPTSAYPLPAPRPLNSRLDTHKLKKTFNLELPHWQKGVTRMLTEIGEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0T6</accession>
    <name>A0A2S9H0T6_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">3-hydroxyacyl-CoA dehydrogenase</fullName>
            <ecNumber evidence="2">1.1.1.35</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">S2091_1578</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>a (3S)-3-hydroxyacyl-CoA + NAD(+) = a 3-oxoacyl-CoA + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:22432"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57318"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:90726"/>
            <dbReference type="EC" id="1.1.1.35"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Lipid metabolism; fatty acid beta-oxidation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.35" evidence="2"/>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93577">
        <property type="protein sequence ID" value="PRC93577"/>
        <property type="gene ID" value="S2091_1578"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00659"/>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003857">
        <property type="term" value="F:3-hydroxyacyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070403">
        <property type="term" value="F:NAD+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006635">
        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006176">
        <property type="entry name" value="3-OHacyl-CoA_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006108">
        <property type="entry name" value="3HC_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00725">
        <property type="entry name" value="3HCDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02737">
        <property type="entry name" value="3HCDH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="4" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="5" id="KW-0520">NAD</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="3HCDH_N" evidence="9">
        <location>
            <begin position="8"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="domain" description="3HCDH" evidence="8">
        <location>
            <begin position="194"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC93577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="796" mass="85811" checksum="7E40210D43C2D485" modified="2018-07-18" version="1">MTNFIVKKVAVLGAGVMGAQIAAHCVNAKVPVVLFDLPAKEGPKNGIVLRAIENLKKLNPAPLGNKDDAAYIEVANYEDNLELLAGCDLIIEAIAERMDWKHDLYKKVAPHIAPNAIFASNTSGLSITALSEGFDAELKARFCGVHFFNPPRYMHLVELIPTVTTAPAIIDQLEGFLTTTLGKGVVRAKDTPNFIANRVGIFGMLATMYEAEKFGLSVDVVDDLTGKKLGRASSGTFRTADVVGLDTMGHVIKTMQDTLQDDPFFSVYKTPEVLTKLIAAGALGQKSGAGFYKKVGKDIQRLDFATAQYVTGGAKADDLVGRILKEKDPVKKMKSLRESTNPQAQFLWAIFRDAFHYIAVHLDTVADNARDIDFAMRWGFGWQVGPFETWQASGWQQVAGWVKEDIDAGKAICSAPLPAWVFEGERTGVHTAEGSWSATSKTYVPRSTLPVYQRQAFRATVLGEGAATGTTAGTTFFEDDSVRIWHQNDDVLIFSMKTKMHVIGPGVIAGMEMALAEAEKNFKGLVIWSADAAEGGAFSAGADLQSMLPLFMSGGVKAIEPMVAKLQQAHMALKYANVPVVAAVAGLALGGGCELMMHTAKRVASIESYIGLVEVGVGLIPAGGGLKEAAVRAAADAKGTDLLQFLKNYFTNAATAAVSKSALEAKKMGYLSADDVIVFNPYELLHVAKVEARAMFDAGYRAPLKAQIPVGGRYSMATITAQLVNMRDGGFISAHDYKLGAMIAEIVSGGEIENGSIVNEQWLLDLERKAFMELLNHPKTQERIMGMMQTGKPVRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0X1</accession>
    <name>A0A2S9H0X1_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 11">Adenylosuccinate lyase</fullName>
            <shortName evidence="11">ASL</shortName>
            <ecNumber evidence="4 11">4.3.2.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10 11">Adenylosuccinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">S2091_1633</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>(2S)-2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate = 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + fumarate</text>
            <dbReference type="Rhea" id="RHEA:23920"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="ChEBI" id="CHEBI:58443"/>
            <dbReference type="ChEBI" id="CHEBI:58475"/>
            <dbReference type="EC" id="4.3.2.2"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="7">
            <dbReference type="Rhea" id="RHEA:23921"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>N(6)-(1,2-dicarboxyethyl)-AMP = AMP + fumarate</text>
            <dbReference type="Rhea" id="RHEA:16853"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="ChEBI" id="CHEBI:57567"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="4.3.2.2"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="8">
            <dbReference type="Rhea" id="RHEA:16854"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 11">Purine metabolism; AMP biosynthesis via de novo pathway; AMP from IMP: step 2/2.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 11">Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.3.2.2" evidence="4 11"/>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93632">
        <property type="protein sequence ID" value="PRC93632"/>
        <property type="gene ID" value="S2091_1633"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00132"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00075">
        <property type="reaction ID" value="UER00336"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070626">
        <property type="term" value="F:(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido) succinate lyase (fumarate-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004018">
        <property type="term" value="F:N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044208">
        <property type="term" value="P:'de novo' AMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.275.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024083">
        <property type="entry name" value="Fumarase/histidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020557">
        <property type="entry name" value="Fumarate_lyase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000362">
        <property type="entry name" value="Fumarate_lyase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022761">
        <property type="entry name" value="Fumarate_lyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008948">
        <property type="entry name" value="L-Aspartase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004769">
        <property type="entry name" value="Pur_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013539">
        <property type="entry name" value="PurB_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08328">
        <property type="entry name" value="ASL_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00206">
        <property type="entry name" value="Lyase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00149">
        <property type="entry name" value="FUMRATELYASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48557">
        <property type="entry name" value="SSF48557"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00928">
        <property type="entry name" value="purB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00163">
        <property type="entry name" value="FUMARATE_LYASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 14" id="KW-0456">Lyase</keyword>
    <keyword evidence="6 11" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lyase_1" evidence="12">
        <location>
            <begin position="14"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="domain" description="ASL_C" evidence="13">
        <location>
            <begin position="331"/>
            <end position="445"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00024487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU361172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF08328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="PRC93632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="455" mass="50338" checksum="04E2ED1F07F8E46E" modified="2018-07-18" version="1">MSLTTLSALSPLDGRYASKVDPLRAILSETGFMHHRVKVEISWLQALSNAGFAEIKPFSASANSFLDKIASEFGEAQAARIKEIEAVTNHDVKAVEYWIKEQVKDVPELLAASEFIHFACTSEDINNTSHGMMLLAARNQVMLPALRNLIAKLTEIAHDNAALPMLSRTHGQPASPTTLGKEIANVVARLQGAVTRIAAVEVLAKMNGAVGNYNAHLSAYPDVDWEAFSKQVIEQRLGLKHNPYTIQIEPHDYMAEMFDAFARANTILLDLNRDIWGYISIGYFKQRTKAGEIGSSTMPHKVNPIDFENSEGNLGLANAVLKHLSEKLPVSRWQRDLTDSTVLRNIGVAFGYTLLAYDSCLRGLNKLEVNPSRIAEDLDATWEVLAEPVQTVMRRYGIENPYEQLKELTRGKGISKDALREFILGLAIPESAKKLLLEMTPANYIGIAAELARKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H146</accession>
    <name>A0A2S9H146_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Putative iron-sulfur cluster insertion protein ErpA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">erpA</name>
        <name evidence="7" type="ORF">S2091_1671</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Required for insertion of 4Fe-4S clusters.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>iron-sulfur cluster</name>
            <dbReference type="ChEBI" id="CHEBI:30408"/>
        </cofactor>
        <text evidence="5">Binds 1 iron-sulfur cluster per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the HesB/IscA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93670">
        <property type="protein sequence ID" value="PRC93670"/>
        <property type="gene ID" value="S2091_1671"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.300.12">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01380">
        <property type="entry name" value="Fe_S_insert_ErpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000361">
        <property type="entry name" value="FeS_biogenesis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016092">
        <property type="entry name" value="FeS_cluster_insertion"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017870">
        <property type="entry name" value="FeS_cluster_insertion_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023063">
        <property type="entry name" value="FeS_cluster_insertion_RrpA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035903">
        <property type="entry name" value="HesB-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01521">
        <property type="entry name" value="Fe-S_biosyn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89360">
        <property type="entry name" value="SSF89360"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00049">
        <property type="entry name" value="TIGR00049"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01152">
        <property type="entry name" value="HESB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0408">Iron</keyword>
    <keyword evidence="4 5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe-S_biosyn" evidence="6">
        <location>
            <begin position="11"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="44"/>
        </location>
        <ligand>
            <name>iron-sulfur cluster</name>
            <dbReference type="ChEBI" id="CHEBI:30408"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="108"/>
        </location>
        <ligand>
            <name>iron-sulfur cluster</name>
            <dbReference type="ChEBI" id="CHEBI:30408"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="110"/>
        </location>
        <ligand>
            <name>iron-sulfur cluster</name>
            <dbReference type="ChEBI" id="CHEBI:30408"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01380"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01521"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC93670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="116" mass="12530" checksum="A34200CC731B1D1B" modified="2018-07-18" version="1">MNAVTEMPAPIIFSDSAAQKVAQLIEEEGNPDLKLRVFVQGGGCSGFQYGFTFDEIVNEDDTTMTKNGVHLLIDSMSYQYLVGAEIDYKDDLEGAQFVIKNPNATTTCGCGSSFSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H147</accession>
    <name>A0A2S9H147_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">tRNA threonylcarbamoyladenosine biosynthesis protein TsaE</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaE</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_1587</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TsaE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93586">
        <property type="protein sequence ID" value="PRC93586"/>
        <property type="gene ID" value="S2091_1587"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002949">
        <property type="term" value="P:tRNA threonylcarbamoyladenosine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003442">
        <property type="entry name" value="T6A_TsaE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02367">
        <property type="entry name" value="TsaE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00150">
        <property type="entry name" value="T6A_YjeE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007599"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00032441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC93586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="161" mass="17593" checksum="E0F216FC6E0585F1" modified="2018-07-18" version="1">MPHYKTQLKNEAATDALGRCLARQLVPGLVIYLHGDLGAGKTALTRALLHAAGYEGHVKSPTYTLAEPYEVQLSGQTVTIMHFDLYRMTSPEEFLEAGFRDVFNHSTICVVEWPENGDGVLPAPDLEVFLTVAGTGRHVELRALSEKGSACLNQLNFAPNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H161</accession>
    <name>A0A2S9H161_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF2807 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1725</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93724">
        <property type="protein sequence ID" value="PRC93724"/>
        <property type="gene ID" value="S2091_1725"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021255">
        <property type="entry name" value="DUF2807"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10988">
        <property type="entry name" value="DUF2807"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF2807" evidence="1">
        <location>
            <begin position="56"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF10988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="270" mass="28352" checksum="DE9D1FE2B4B5F619" modified="2018-07-18" version="1">MMKFIAKSMLALLLVAIALGGITYNVMSTNLKQNGTITLATQNLSKENVAITNEVEKVEMDGPFDVNLVQADKSSLVLEGDARLLSKVVVQQDGNTLRIGTKGILVTMNQTLKMTLSIPKLTALTQFGSGDSTVQGFTGPQININLNGSGDLAFAGQYEHLMAQTKGSGNMELDVGKSDKVELNTSGSGDVVALGKAMDLVILTTGSGNIDAQRLIAQHSSGESHGSGDLKLYATQDVRVILTGSGDAEVFGNPAKRSVTNTGSGDMSWN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H170</accession>
    <name>A0A2S9H170_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Eukaryotic-type carbonic anhydrase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_1735</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93734">
        <property type="protein sequence ID" value="PRC93734"/>
        <property type="gene ID" value="S2091_1735"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004089">
        <property type="term" value="F:carbonate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03124">
        <property type="entry name" value="alpha_CA_prokaryotic_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041891">
        <property type="entry name" value="Alpha_CA_prokaryot-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001148">
        <property type="entry name" value="CA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036398">
        <property type="entry name" value="CA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023561">
        <property type="entry name" value="Carbonic_anhydrase_a-class"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18952">
        <property type="entry name" value="PTHR18952"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00194">
        <property type="entry name" value="Carb_anhydrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01057">
        <property type="entry name" value="Carb_anhydrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51069">
        <property type="entry name" value="SSF51069"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51144">
        <property type="entry name" value="ALPHA_CA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015647439" evidence="2">
        <location>
            <begin position="32"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha-carbonic anhydrase" evidence="3">
        <location>
            <begin position="142"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC93734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="364" mass="40231" checksum="6B1DD1615EC60350" modified="2018-07-18" version="1">MRSSTASVLPLLCSLLCSLLIAAFFSGTTYAAEDSSPPSKPIVKDTLPIKIKPTENADGESKPKSKSSAKSAAAQHDKEEMEADELADKIAKKMAELHKENERIKAQTPMVRHPRAATSASAVSPGMPHGANLAADNIMHFVPWSYDGEGGPLRWGKIDPANAKCDTGERQSPIDIRDGIRVDLEPVIFDYKPTRFNVVDTGHTIQVNLGAGSTITILGRRYELTQFHFHKPSEERVNGRNYEMVAHLVHKDIDGKLVMLAVLIEQGKANSLIQTIWNNMPLEKNDTVQPSGTIDMYQILPANRQYYTYMGSLTTPPCTEGVLWVVFKEPIEASQDQISIFSRMYPMNARPIQNSAGRLIKESN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H172</accession>
    <name>A0A2S9H172_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1730</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93729">
        <property type="protein sequence ID" value="PRC93729"/>
        <property type="gene ID" value="S2091_1730"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010710">
        <property type="entry name" value="DUF1289"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35175">
        <property type="entry name" value="PTHR35175"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06945">
        <property type="entry name" value="DUF1289"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="74" mass="8286" checksum="82177A6F646890CE" modified="2018-07-18" version="1">MNTINSSVAVTPSPCTNICKIDAQTGWCEGCWRTIDEIAGWGSAGEPVKELIMQNIEQRKIQQHQHDLSQFDPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1G6</accession>
    <name>A0A2S9H1G6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1431</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93822">
        <property type="protein sequence ID" value="PRC93822"/>
        <property type="gene ID" value="S2091_1431"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015522268" evidence="1">
        <location>
            <begin position="24"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="224" mass="23707" checksum="110572AE3DBDB656" modified="2018-07-18" version="1">MKLHYTAAVLLPFILLSANTARADDNFVYGTIGQGIGAGFGRVINDNFSVRADVDRVGSPVYQHNFGNNNYDIKSEASTRLNVLVDWFPITGSGFRVSGGLGFSNDQSYNSIATPNSSGNYIINGNTYSANTVGQLKATSTFNKVIPQIGIGWDSAPANKPGWRLMTGLNLSLISSGKTTLAATNSAQNSALLADVGAEQSRVNSDFGRHAAQLNVSVGVGYSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1V4</accession>
    <name>A0A2S9H1V4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1455</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93846">
        <property type="protein sequence ID" value="PRC93846"/>
        <property type="gene ID" value="S2091_1455"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="SSF56672"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="439" mass="49064" checksum="04C080CD230B38C3" modified="2018-07-18" version="1">MRAGGVATVSPATIVLDRNLDKEGIALNAIAIALLQFTPEVTCADDFCILLDVSASLTLFNGPLAICRRINASVKALGFTMTLGAAPTATGAWLLSRSHRKKFRPLRHRAVTMKTLTALLNHLSCTSLSATLPYAEWLSGIGACTLGDLRKLPRPGLLRRTDQHLLEELDRAYGLAPELFDWIKTPATFSARMETFDRIEHADALMFGATRLILQLIGWLVSLQQAVSIFVLHLEHERGRYAIAPTEIEIGLAESAWHEEHLIRLLQERLGRIELVAPVIAIRLEVRKVTAMLPPTMSLFPEPGGSPADLNRLLELLIARLGKSNVLTPACVDDYRPEICNTWVPATDKLSNKNESSNIVERPFWILAKPIALLMRDDRPFYGSPLKLVRGPERVEAGWWDSQTIARDYFVAQNTESSCYWIYLERTSEPHWFLHGLYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H205</accession>
    <name>A0A2S9H205_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ABC-type multidrug transport system ATPase component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_1185</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94012">
        <property type="protein sequence ID" value="PRC94012"/>
        <property type="gene ID" value="S2091_1185"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-1278">Translocase</keyword>
    <feature type="domain" description="ABC transporter" evidence="7">
        <location>
            <begin position="4"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="36"/>
            <end position="43"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC94012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="302" mass="32861" checksum="D753DC4661204D6A" modified="2018-07-18" version="1">MAALQITDIKKNYAALQALDGVSLTVEQGEFFGLLGPNGAGKTTLISIIAGLNRATSGHVSVMGHDVVSDYRAARRQLGVVPQELVFDPFFTVRETLRMQLGYYGLKRNDAWIDEIMENLDLTNKADTNMRALSGGMKRRVLVAQALVHKPPVIVLDEPTAGVDVELRQTLWQFIGRLNREGHTIVLTTHYLEEAQALCSRIAMLKAGKVVALDTTAALLQRVAGSQLKLRLSGAALPASLRALQIPNDSSHTGTILRVNDSTEIEPILASLRQAGCVIDDLQLQQADLEDVFLQIMGGAQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2B6</accession>
    <name>A0A2S9H2B6_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">50S ribosomal protein L30</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpmD</name>
        <name evidence="7" type="ORF">S2091_1297</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2 5">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the universal ribosomal protein uL30 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94124">
        <property type="protein sequence ID" value="PRC94124"/>
        <property type="gene ID" value="S2091_1297"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01658">
        <property type="entry name" value="Ribosomal_L30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1390.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01371_B">
        <property type="entry name" value="Ribosomal_L30_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036919">
        <property type="entry name" value="L30_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005996">
        <property type="entry name" value="Ribosomal_L30_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016082">
        <property type="entry name" value="Ribosomal_L30_ferredoxin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15892">
        <property type="entry name" value="PTHR15892"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00327">
        <property type="entry name" value="Ribosomal_L30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002211">
        <property type="entry name" value="Ribosomal_L30_bac-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55129">
        <property type="entry name" value="SSF55129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01308">
        <property type="entry name" value="rpmD_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Ribosomal_L30" evidence="6">
        <location>
            <begin position="5"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00327"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC94124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="59" mass="6481" checksum="82683F394BC039EC" modified="2018-07-18" version="1">MTKTVKVTLVKGLIGTRESHRATVRGLGLRRINSVSELQDTPSVRGMINKVSYLVKVVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2V9</accession>
    <name>A0A2S9H2V9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0935</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94314">
        <property type="protein sequence ID" value="PRC94314"/>
        <property type="gene ID" value="S2091_0935"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="396" mass="42416" checksum="23B7905A2A772203" modified="2018-07-18" version="1">MRVKTGAQTDLSKQPQSLTSSHPTQLMATPQIVVEDLRPQLAQQKVIQAQMVNSFPQQTLMAMQAKMDNSQQRQSMPRMDTRNITPSIQRLAKNEKQHSDFSGPRPAENSTIQRMLVPFKTPAAANADQTNIITDANVIEGITNAAYVNTWNRLNAATLPGAAVPLAQAQFPGVTNGHFAHFVNTMAGNNGALKAAAVGYVIEDQVTHNGALPATAAPQTPSGNAILDFVITRNAERGIVDITSTGQAGHVLNKSFTKGPFSYIGESMYQSIDFTQLNGGAAPQIGVAAAALALAAKRQRANNFIGSQLNQLKQSIELYKMGIKHNDGGFEMESNTVVEGINALPNGAYPPADIIQLDLDIATMNLGLGAAFQLNTLTQIITAAQNNYLLAGNPMW</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H387</accession>
    <name>A0A2S9H387_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Adenosylhomocysteinase</fullName>
            <ecNumber evidence="4">3.3.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">S-adenosyl-L-homocysteine hydrolase</fullName>
            <shortName evidence="4">AdoHcyase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ahcY</name>
        <name evidence="9" type="ORF">S2091_1051</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4 6">
            <text>H2O + S-adenosyl-L-homocysteine = adenosine + L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:21708"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16335"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:58199"/>
            <dbReference type="EC" id="3.3.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4 6">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
        <text evidence="4 6">Binds 1 NAD(+) per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4 6">Amino-acid biosynthesis; L-homocysteine biosynthesis; L-homocysteine from S-adenosyl-L-homocysteine: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4 7">Belongs to the adenosylhomocysteinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.3.1.1" evidence="4"/>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94430">
        <property type="protein sequence ID" value="PRC94430"/>
        <property type="gene ID" value="S2091_1051"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00314">
        <property type="reaction ID" value="UER00076"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004013">
        <property type="term" value="F:adenosylhomocysteinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006730">
        <property type="term" value="P:one-carbon metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00401">
        <property type="entry name" value="SAHH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1480">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00563">
        <property type="entry name" value="AdoHcyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042172">
        <property type="entry name" value="Adenosylhomocyst_ase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000043">
        <property type="entry name" value="Adenosylhomocysteinase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015878">
        <property type="entry name" value="Ado_hCys_hydrolase_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020082">
        <property type="entry name" value="S-Ado-L-homoCys_hydrolase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23420">
        <property type="entry name" value="PTHR23420"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05221">
        <property type="entry name" value="AdoHcyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00670">
        <property type="entry name" value="AdoHcyase_NAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001109">
        <property type="entry name" value="Ad_hcy_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00996">
        <property type="entry name" value="AdoHcyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00997">
        <property type="entry name" value="AdoHcyase_NAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00936">
        <property type="entry name" value="ahcY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00738">
        <property type="entry name" value="ADOHCYASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00739">
        <property type="entry name" value="ADOHCYASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 4 6" id="KW-0520">NAD</keyword>
    <keyword evidence="2 4 6" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AdoHcyase_NAD" evidence="8">
        <location>
            <begin position="229"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4 5">
        <location>
            <position position="60"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4 5">
        <location>
            <position position="134"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4 5">
        <location>
            <position position="194"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="195"/>
            <end position="197"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4 5">
        <location>
            <position position="224"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4 5">
        <location>
            <position position="228"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="229"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="258"/>
            <end position="263"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="281"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="316"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="337"/>
            <end position="339"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="382"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR001109-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC94430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="468" mass="51469" checksum="28C34879BC7D5FB9" modified="2018-07-18" version="1">MNAINKNKDYLVADISLAAWGRKEINIAETEMPGLMAIREEFAASQPLRGARIAGSLHMTIQTAVLIETLTALGAEVRWASCNIYSTQDQAAAAIAEAGHPVFAFKGENLDEYWEFTHRIFDWADQPANMILDDGGDATLLLHLGSRAEKDSSVLNNPGSEEEICLFNSIKKHLTVDGSWYSTRLAAIKGVTEETTTGVHRLYQMHKEGKLAFPAINVNDSVTKSKFDNLYGCRESLVDGIKRATDVMIAGKVAVIIGYGDVGKGCAQAMRALSAQVWVTEIDPICALQAAMEGYRVVTMEYAAAQGDIFVTTTGNYHVITHEHMLAMKDQAIVSNIGHFDNEIDVASLEKYEWDNIKPQVDHVIFPSGKRIILLAKGRLVNLGCGTGHPSYVMSSSFANQTIAQIELFANPGKYPVGVYTLPKHLDEKVARLQLKKLNAQLSVLTDQQAAYIGVPKEGPYKTDHYRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3A4</accession>
    <name>A0A2S9H3A4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Prc: C-terminal processing peptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_1080</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the peptidase S41A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94459">
        <property type="protein sequence ID" value="PRC94459"/>
        <property type="gene ID" value="S2091_1080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07560">
        <property type="entry name" value="Peptidase_S41_CPP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041489">
        <property type="entry name" value="PDZ_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004447">
        <property type="entry name" value="Peptidase_S41A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005151">
        <property type="entry name" value="Tail-specific_protease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17820">
        <property type="entry name" value="PDZ_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03572">
        <property type="entry name" value="Peptidase_S41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00245">
        <property type="entry name" value="TSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="SSF50156"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00225">
        <property type="entry name" value="prc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0720">Serine protease</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015761289" evidence="5">
        <location>
            <begin position="30"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="domain" description="PDZ" evidence="6">
        <location>
            <begin position="88"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="400"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="460"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="463"/>
            <end position="491"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC94459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="510" mass="54904" checksum="2E974A6CDC7CB338" modified="2018-07-18" version="1">MGNKLKNFGLITLGLVAGVAASLQFSAMAQKTATPLPIEELRQLADVFGLIKSDYVEPVDDSKLISEAISGMVASLDPHSVYLDKKAFKELQETTQGKFVGLGIEVGMEDGFVKIISPIEDSPADKAGVKAGDLITRLDSLSVKGMTLDEAVKHMRGEPDTKVTLTIARKNVDKPIILTITRALIKTQSVKGKMIEPGYAWLRVSQFQEPSLDDLVKKINALYAQDPHIKGLVLDLRNNPGGLVPSAIGISAIFLPKDVTVVTTNGQIPESKANYTASREFYSTRNGPDALAKLPEAIKNVPMVVLVNTGSASASEIVSGALQDYKRAVIMGTQTFGKGSVQTIRQISADTGVKLTTARYYTPNGRSIQAKGITPDLNVEETAENDGINSLRLREADLQKHLDNDKDSTAGTEKRDEAADEKHALEIEKTLKPLEYGSATDFQLMQALNHLKGLPVQLAKVADKADAESKDDAKSDKKSDKKSDEKTDNKTKAPAATPAIPDASIPATKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3D0</accession>
    <name>A0A2S9H3D0_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8">Diaminopimelate epimerase</fullName>
            <shortName evidence="8">DAP epimerase</shortName>
            <ecNumber evidence="4 8">5.1.1.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">PLP-independent amino acid racemase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">dapF</name>
        <name evidence="10" type="ORF">S2091_1064</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>(2S,6S)-2,6-diaminoheptanedioate = meso-2,6-diaminoheptanedioate</text>
            <dbReference type="Rhea" id="RHEA:15393"/>
            <dbReference type="ChEBI" id="CHEBI:57609"/>
            <dbReference type="ChEBI" id="CHEBI:57791"/>
            <dbReference type="EC" id="5.1.1.7"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; DL-2,6-diaminopimelate from LL-2,6-diaminopimelate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the diaminopimelate epimerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.1.1.7" evidence="4 8"/>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94443">
        <property type="protein sequence ID" value="PRC94443"/>
        <property type="gene ID" value="S2091_1064"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00034">
        <property type="reaction ID" value="UER00025"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008837">
        <property type="term" value="F:diaminopimelate epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00197">
        <property type="entry name" value="DAP_epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018510">
        <property type="entry name" value="DAP_epimerase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001653">
        <property type="entry name" value="DAP_epimerase_DapF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31689">
        <property type="entry name" value="PTHR31689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01678">
        <property type="entry name" value="DAP_epimerase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00652">
        <property type="entry name" value="DapF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01326">
        <property type="entry name" value="DAP_EPIMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6 8" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="8">
        <location>
            <begin position="76"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="8">
        <location>
            <begin position="221"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="8">
        <location>
            <begin position="231"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="75"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="8">
        <location>
            <position position="75"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="230"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="13"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="46"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="66"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="170"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="203"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Could be important to modulate the pK values of the two catalytic cysteine residues" evidence="8">
        <location>
            <position position="172"/>
        </location>
    </feature>
    <feature type="site" description="Could be important to modulate the pK values of the two catalytic cysteine residues" evidence="8">
        <location>
            <position position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000599"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00197"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC94443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="287" mass="31125" checksum="7F953EE9F2A25762" modified="2018-07-18" version="1">MKIKFTKMHGAGNDFLVFNGIHQQIAFTPEQWKKLADRRFGVGADQMLVVERSTLPEVDFRYRIFNADGGEVEHCGNGARAFVKFVHEKKLIKKTRIKVEIMKGIIELNLETDGSVTVDMNAPILDATQVPFDTTDLVSKTEAQATLWPLNVGKKTGKSAVLISVVSMGNPHAVQIVTDVDAAPVLTDGPLIECHPRFPHHVNAGFMQIIDQHNIKLRVFERGAGETLACGTGACAAVVAGILRGHLTSPVQVTARGGELTISWAGVGQSVFLTGPAVTVFEGEFNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3I6</accession>
    <name>A0A2S9H3I6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_0533</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94530">
        <property type="protein sequence ID" value="PRC94530"/>
        <property type="gene ID" value="S2091_0533"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000485">
        <property type="entry name" value="AsnC-type_HTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019888">
        <property type="entry name" value="Tscrpt_reg_AsnC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019887">
        <property type="entry name" value="Tscrpt_reg_AsnC/Lrp_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019885">
        <property type="entry name" value="Tscrpt_reg_HTH_AsnC-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01037">
        <property type="entry name" value="AsnC_trans_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00033">
        <property type="entry name" value="HTHASNC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00344">
        <property type="entry name" value="HTH_ASNC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00519">
        <property type="entry name" value="HTH_ASNC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50956">
        <property type="entry name" value="HTH_ASNC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH asnC-type" evidence="4">
        <location>
            <begin position="11"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC94530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="162" mass="18513" checksum="C28F9556CA57C2C4" modified="2018-07-18" version="1">MRIQKNTVRALDKLDRRILSLLQKDGRLSMKDLGEQVGLSITPCIERVKRMERDGIISGYYARLNPAALGASLLMFVQITLSNKSGEMFDQFRREVLRIPQVLECHLVSGDFDYIIKARIHEMSEYRKLLGDILLQLPGAAQSKSYVVMEEIKETLALDVEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3K1</accession>
    <name>A0A2S9H3K1_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CENP-V/GFA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_0544</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Gfa family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94541">
        <property type="protein sequence ID" value="PRC94541"/>
        <property type="gene ID" value="S2091_0544"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016846">
        <property type="term" value="F:carbon-sulfur lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006913">
        <property type="entry name" value="CENP-V/GFA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011057">
        <property type="entry name" value="Mss4-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04828">
        <property type="entry name" value="GFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51316">
        <property type="entry name" value="SSF51316"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51891">
        <property type="entry name" value="CENP_V_GFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CENP-V/GFA" evidence="3">
        <location>
            <begin position="2"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC94541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="132" mass="14464" checksum="0C4EE9BC6950D2D2" modified="2018-07-18" version="1">MLTGGCYCGLVRYQAEGSASHLVNCHCSICRRTSGAPFVSWFTVPRTAFQFTQGTPTQFKSTEQGLRCFCPDCGTQLSFQHVDTPDEIDLTICSLDNPESLPPEKHIHMESKLSWISLADGLAGTSEANSEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3L7</accession>
    <name>A0A2S9H3L7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Lysine efflux permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_0578</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94575">
        <property type="protein sequence ID" value="PRC94575"/>
        <property type="gene ID" value="S2091_0578"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001123">
        <property type="entry name" value="LeuE-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30086">
        <property type="entry name" value="PTHR30086"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01810">
        <property type="entry name" value="LysE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="39"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="68"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="106"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="146"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="177"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC94575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="200" mass="21059" checksum="C83D1606E5628077" modified="2018-07-18" version="1">MIFAFLKGLGIGASLIIAIGAQNAFVLRQGLLRHHVFTSALICTLCDMALIYAGVAGMGTLISAAPNLLIFAKWGGAAFLFAYGARSAWAAFHSGGLTSKEEAPRSHMAIVVSAFSFSLLNPHVYLDTVVLLGTVGGQQVGIARNLFAAGAMTASTIWFFGLAYGARLLAPLFAQPIAWRILDGLIAIVMWLIAVSLLCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3N2</accession>
    <name>A0A2S9H3N2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NADPH:quinone reductase and related Zn-dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0592</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94589">
        <property type="protein sequence ID" value="PRC94589"/>
        <property type="gene ID" value="S2091_0592"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PKS_ER" evidence="1">
        <location>
            <begin position="12"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="330" mass="34809" checksum="A7D46032A3AD5741" modified="2018-07-18" version="1">MQAAWYESRGPAREVLVVGTMLEPQPAPGEVRIRLAFSGISPGDVKKRGGWQGAPMPYPRVIPHSDGAGVIDAVGVGVPSSRIGQTVWCYGAQSYRPFGTAAESVIVPSAMAVSLPEGAAVQANVLEQAACLGITGITGYQAVFAAGPVNGLNVLVWGAGSGVGAVALQMARRAGARVMAVVRRPEQQTALREQGVNNTWLADDPALITYIKQAAPEGVHRVAEVDFAAHIDTNAEIMAIGGVIAAYYSSDNRPSIPYWKLGFSDVSLRLLGSDDFAPQVKERAAEELTKALMDGSLSIPVTRRLPLTEIALAHEHIEQGFSGRVVLGFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3P5</accession>
    <name>A0A2S9H3P5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0556</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94553">
        <property type="protein sequence ID" value="PRC94553"/>
        <property type="gene ID" value="S2091_0556"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="113" mass="12815" checksum="8EE06108F1BB46FB" modified="2018-07-18" version="1">MDITISHQDFKTQLLEIRISGFFCSSRVLLNGVEVKRVQGVYTVLNDVGYEVAIELNSSLLNPIPIVRVDAEKINLANATEWSQFTGWGKTSPLQRFKSKVRMLLMSFPLKKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3U8</accession>
    <name>A0A2S9H3U8_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_0650</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94647">
        <property type="protein sequence ID" value="PRC94647"/>
        <property type="gene ID" value="S2091_0650"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024478">
        <property type="entry name" value="HlyB_4HB_MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12729">
        <property type="entry name" value="4HB_MCP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="191"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="5">
        <location>
            <begin position="305"/>
            <end position="540"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC94647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="545" mass="59946" checksum="14DEE296CE280782" modified="2018-07-18" version="1">MRFPKSTIGQRLTWSYGTVVALLIVVAFFGIYKLGSLSRITDATLREKYPATIVVNQLSNDLNIIAREMRNTLIFNDQAHLQDQLNEINKAKINMAAELEQVQLKMTDPDSKELLNEIKIVHSAYLVNQEDFIHLVAEHKMGEARNLLLVDLNGYQDIYFELLEKLRADQINLMTLASKEVEDTYFSARKLMFILSALAIVLSIGITVIITRSLLKQLGGEPDYAVSIAKKIALGDLSSFIALDSNDHSSLLYSMSAMRESLIERTNALQDTNRELALTIETLNQAQADLIFNEKLAALGSLVAGIAHELNTPIGNGIMAASTLIEFSKAFEAKSVNGVSRASLKMYLAQMQEGADILQRNLDRAGSLIASFKQVAVDRTTSGARRFALAEVISEIILTLQPAIKKRPHLIKQDIPPEIMMDSYPGPLGQVLTNLINNALIHGFDQRESGNDPGIISISARTLSDSHIEIKVHDNGCGISPDNLSRIYDPFFTTKFGKGGSGLGLHISHNIVCGVLGGKIHVDSELKVGTTFILTLPVKATNLQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H463</accession>
    <name>A0A2S9H463_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Protein-methionine-sulfoxide reductase heme-binding subunit MsrQ</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Flavocytochrome MsrQ</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">msrQ</name>
        <name evidence="9" type="ORF">S2091_0775</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
        <text evidence="7">Binds 1 FMN per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
        <text evidence="7">Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the MsrQ family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94772">
        <property type="protein sequence ID" value="PRC94772"/>
        <property type="gene ID" value="S2091_0775"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030091">
        <property type="term" value="P:protein repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01207">
        <property type="entry name" value="MsrQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013130">
        <property type="entry name" value="Fe3_Rdtase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022837">
        <property type="entry name" value="MsrQ-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36964">
        <property type="entry name" value="PTHR36964"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01794">
        <property type="entry name" value="Ferric_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0249">Electron transport</keyword>
    <keyword evidence="7" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-0288">FMN</keyword>
    <keyword evidence="7" id="KW-0349">Heme</keyword>
    <keyword evidence="5 7" id="KW-0408">Iron</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="51"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="80"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="114"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="153"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="180"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="domain" description="Ferric oxidoreductase" evidence="8">
        <location>
            <begin position="53"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC94772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="209" mass="24290" checksum="00BCCAFB83A3B4F2" modified="2018-07-18" version="1">MTPTLKQQSIIKASLFVAALLPFLRLVLAVFTDHLGANPLEFITRNTGDWTLYFLCITLAVTPLRRLTGWSWMVKLRRMLGLYGFFYASLHFLTFLWFDHFFDVAEMLKDVVKRPFILVGFTAFILLMPLALTSTNKMIKRVGAKRWQQLHKLIYLIASLGVLHYFWMKAGKHDFSQPVLFGSIVAILLLLRLFWAIQKRQHEQRLSVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4F0</accession>
    <name>A0A2S9H4F0_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">tRNA-cytidine(32) 2-sulfurtransferase</fullName>
            <ecNumber evidence="6">2.8.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Two-thiocytidine biosynthesis protein A</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">tRNA 2-thiocytidine biosynthesis protein TtcA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ttcA</name>
        <name evidence="8" type="ORF">S2091_0759</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>AH2 + ATP + cytidine(32) in tRNA + S-sulfanyl-L-cysteinyl-[cysteine desulfurase] = 2-thiocytidine(32) in tRNA + A + AMP + diphosphate + H(+) + L-cysteinyl-[cysteine desulfurase]</text>
            <dbReference type="Rhea" id="RHEA:57048"/>
            <dbReference type="Rhea" id="RHEA-COMP:10288"/>
            <dbReference type="Rhea" id="RHEA-COMP:12157"/>
            <dbReference type="Rhea" id="RHEA-COMP:12158"/>
            <dbReference type="Rhea" id="RHEA-COMP:14821"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61963"/>
            <dbReference type="ChEBI" id="CHEBI:82748"/>
            <dbReference type="ChEBI" id="CHEBI:141453"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="6">Binds 1 [4Fe-4S] cluster per subunit. The cluster is chelated by three Cys residues, the fourth Fe has a free coordination site that may bind a sulfur atom transferred from the persulfide of IscS.</text>
    </comment>
    <comment type="pathway">
        <text evidence="6">tRNA modification.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="6">The thiolation reaction likely consists of two steps: a first activation step by ATP to form an adenylated intermediate of the target base of tRNA, and a second nucleophilic substitution step of the sulfur (S) atom supplied by the hydrosulfide attached to the Fe-S cluster.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the TtcA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.-" evidence="6"/>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94756">
        <property type="protein sequence ID" value="PRC94756"/>
        <property type="gene ID" value="S2091_0759"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00705"/>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016783">
        <property type="term" value="F:sulfurtransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034227">
        <property type="term" value="P:tRNA thio-modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01850">
        <property type="entry name" value="TtcA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011063">
        <property type="entry name" value="TilS/TtcA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012089">
        <property type="entry name" value="tRNA_Cyd_32_2_STrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035107">
        <property type="entry name" value="tRNA_thiolation_TtcA_Ctu1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01171">
        <property type="entry name" value="ATP_bind_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004976">
        <property type="entry name" value="ATPase_YdaO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6" id="KW-0408">Iron</keyword>
    <keyword evidence="5 6" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 6" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 6" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="6" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="ATP_bind_3" evidence="7">
        <location>
            <begin position="49"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="PP-loop motif" evidence="6">
        <location>
            <begin position="55"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="130"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="133"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="221"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC94756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="306" mass="34501" checksum="9815A9D96CD72101" modified="2018-07-18" version="1">MNATLSAAEPLSIKSIEKITYENNKLHKRLCRQVGQAIGDFNMIEDGDKVMVCLSGGKDSYALLDILLTLRERAPINFDIVAVNLDQKQPNFPADILPAYLTKLGVPFHIENQDTYSIVKRVIEEGKTTCSLCSRLRRGILYRVADELGANKIALGHHRDDILETFFLNMFFGAKIKGMPAKLQSDDGKHMVIRPMAYVKEEDTFRYAEVKKFPIIPCDLCGSQENLQRKQIKGLMREWEKKHPGRVESIFSAISTVVPSHLMDRDLFNFKDLNIDGKAKPEGDIAFDDEPCAPPQAFNTISITPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4H6</accession>
    <name>A0A2S9H4H6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cytochrome c</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_0038</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="PTM">
        <text evidence="4">Binds 2 heme c groups covalently per subunit.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94843">
        <property type="protein sequence ID" value="PRC94843"/>
        <property type="gene ID" value="S2091_0038"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024167">
        <property type="entry name" value="Cytochrome_c4-like"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000005">
        <property type="entry name" value="Cytochrome_c4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4 6" id="KW-0349">Heme</keyword>
    <keyword evidence="3 5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="2 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cytochrome c" evidence="7">
        <location>
            <begin position="15"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="7">
        <location>
            <begin position="116"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="binding site" description="covalent" evidence="4">
        <location>
            <position position="35"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="4">
        <location>
            <position position="38"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="39"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="79"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="covalent" evidence="4">
        <location>
            <position position="137"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="4">
        <location>
            <position position="140"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="141"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>2</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="183"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>2</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000005-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000005-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC94843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="243" mass="26069" checksum="11A2720F0D355978" modified="2018-07-18" version="1">MALFSLFNVVTAPASAYETGQAVAPDTMAERVKACVICHTPQDKVGSDAYYPRIAGKPAGYLYHQLQNFRDGRRNYTAMTNLLDPLSDDYIKKIAQYFSEQHPAYAPLASTAVTPALFERGQVLIHQGDPAKNIPACVACHGTALLGVAPFIPGLLGLPRDYINAQFGAMRNGTRRNAAPDCMAEIAQHLSSEDINSVATWLSAQKISSGDQPATSLPNLMPLKCGSVSSVKSVDIVNSEVAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4J8</accession>
    <name>A0A2S9H4J8_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 11">Ribosomal RNA small subunit methyltransferase E</fullName>
            <ecNumber evidence="4 11">2.1.1.193</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">S2091_0056</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10 11">Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>S-adenosyl-L-methionine + uridine(1498) in 16S rRNA = H(+) + N(3)-methyluridine(1498) in 16S rRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42920"/>
            <dbReference type="Rhea" id="RHEA-COMP:10283"/>
            <dbReference type="Rhea" id="RHEA-COMP:10284"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74502"/>
            <dbReference type="EC" id="2.1.1.193"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the RNA methyltransferase RsmE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.193" evidence="4 11"/>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="SMR" id="A0A2S9H4J8"/>
    <dbReference type="EnsemblBacteria" id="PRC94861">
        <property type="protein sequence ID" value="PRC94861"/>
        <property type="gene ID" value="S2091_0056"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006700">
        <property type="entry name" value="rRNA_ssu_MeTrfase-E"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30027">
        <property type="entry name" value="PTHR30027"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04452">
        <property type="entry name" value="Methyltrans_RNA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015601">
        <property type="entry name" value="MTase_slr0722"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="SSF75217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="SSF88697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00046">
        <property type="entry name" value="TIGR00046"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 11 12" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 11" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="11" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="9 11 12" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00025699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR015601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PRC94861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="241" mass="26432" checksum="F85DB4C00A9F4490" modified="2018-07-18" version="1">MPRFFYPSELAIGALINLPDTVAHHCQVLRLNAGDPIVLFNGKGGSYVASLTSIEKKRATAEVKTFNQNEVELAYSITLAQALPEASKMDWIIEKAVELGAVGIQPLTTQRCVTRLSGERVEKRRAHWQAIIESASEQCGRNRLAQLGQLADFKSWISQQDLHRRIILSPHSDQSLADWARHHPAQAITLMIGPEGGFTEQEHLLAINQGALSLSMGARVLRTETAGLTAIATVNAFWGGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4L5</accession>
    <name>A0A2S9H4L5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_0114</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94919">
        <property type="protein sequence ID" value="PRC94919"/>
        <property type="gene ID" value="S2091_0114"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011935">
        <property type="entry name" value="CHP02231"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037291">
        <property type="entry name" value="DUF4139"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025554">
        <property type="entry name" value="DUF4140"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31005">
        <property type="entry name" value="PTHR31005"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13598">
        <property type="entry name" value="DUF4139"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13600">
        <property type="entry name" value="DUF4140"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02231">
        <property type="entry name" value="TIGR02231"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015696495" evidence="2">
        <location>
            <begin position="22"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4140" evidence="4">
        <location>
            <begin position="30"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4139" evidence="3">
        <location>
            <begin position="212"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="166"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC94919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="533" mass="58032" checksum="294A0F54516E1A9E" modified="2018-07-18" version="1">MRIKLLLSCSLLASTSHYALADMTAPITDVILFPGSATIVRTVAVTAGNTQVVIPGLPARFDAQTLHAEAAAGIRIGEITTKDIARTEARSKTEADMEAQIQALEDQTAMLDADAKSADIVKTYLERLGGDSTGADKQSRSPIDAKTLAGLIDTIGRGANDALSKMQRIIVQKREIEKKIAALKRDLARQHTNDNDARTVSINVNADRAGLVKLSYQINNAGWKPAYRASLDSVASKVELERLATISQKTGEDWSNIKLTLSTNQPRLSPVGPDPKPWLLSYYAPAPPPVSSPAPANYSAQKIMVTGSRISRADMEENYEPPTFETQSTFSTQFEVPTRVNLQSDGREVSVTLAKQTLAVKQMLRITPRLDRAAIVMAVAEQPQGVWPQGTMQLIRDGNYVGASAWNPQANENLSLSYGRDDLVKVEVNPVKTNSASTGIFDKKSERKLADVFSITNTHKTAIEIEVLESSPVSTSDEIKVQALFDPKPSNDAWEQRRGVVAWKKTVQPNATAKFSVDYTIEYPKEGSVGGLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4L8</accession>
    <name>A0A2S9H4L8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">GGDEF: diguanylate cyclase (GGDEF) domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_0125</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94930">
        <property type="protein sequence ID" value="PRC94930"/>
        <property type="gene ID" value="S2091_0125"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="12"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="3">
        <location>
            <begin position="170"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC94930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="314" mass="34814" checksum="978B3530AB02A1E4" modified="2018-07-18" version="1">MTTDSPIEEPCSILIIDDSPTAVRMLADMLKDLGHITFATNGEAGLKFAQEIQPQLILLDVEMPSMNGYEVCQRLKANPTTSESAVIFVTSDSTMESEIKALEMGAVDFITKPLNQPVVRARVRTQLKLSQQAAALSRLVNRDELTGLYNRRYFNEVIESEFQRLRRQELSLGLAFIDIDHFKKFNDRYGHQEGDRCLQKVASSLNNATLRSGELVARYGGEEFVAVLPHISIDQVAIYGEKLCKAISDCGIIHQDSEFGIVTISVGVTAAIPTSTISVHQLIKETDKALYASKSTGRNRCTTWAHSELNNNST</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4R8</accession>
    <name>A0A2S9H4R8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0128</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94933">
        <property type="protein sequence ID" value="PRC94933"/>
        <property type="gene ID" value="S2091_0128"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023187">
        <property type="entry name" value="Tscrpt_reg_MarR-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01047">
        <property type="entry name" value="MarR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00347">
        <property type="entry name" value="HTH_MARR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01117">
        <property type="entry name" value="HTH_MARR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50995">
        <property type="entry name" value="HTH_MARR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="1">
        <location>
            <begin position="3"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="142" mass="15596" checksum="4B8E6CD263FBDAD3" modified="2018-07-18" version="1">MSQKNIETAAIDFTQAVGLLVRRLRAVAATQGLSMTESVVMARLEKEGPATIADLARAEGMKPQSMGTTVAALEEMDLIVRKAHPTDGRQMLIELSDNGLALRKSTGDAKRTWLTQAIAQLDETERETLYQASDIIRRLVEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4U4</accession>
    <name>A0A2S9H4U4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Electron transfer flavoprotein alpha subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_0194</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ETF alpha-subunit/FixB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94999">
        <property type="protein sequence ID" value="PRC94999"/>
        <property type="gene ID" value="S2091_0194"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01715">
        <property type="entry name" value="ETF_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014730">
        <property type="entry name" value="ETF_a/b_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001308">
        <property type="entry name" value="ETF_a/FixB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033947">
        <property type="entry name" value="ETF_alpha_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014731">
        <property type="entry name" value="ETF_asu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018206">
        <property type="entry name" value="ETF_asu_C_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43153">
        <property type="entry name" value="PTHR43153"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01012">
        <property type="entry name" value="ETF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00766">
        <property type="entry name" value="ETF_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000089">
        <property type="entry name" value="Electra_flavoP_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00893">
        <property type="entry name" value="ETF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="SSF52467"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00696">
        <property type="entry name" value="ETF_ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0249">Electron transport</keyword>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ETF" evidence="6">
        <location>
            <begin position="3"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC94999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="309" mass="31359" checksum="379845C2DE6CD295" modified="2018-07-18" version="1">MTTLVIAEHDNVSLKGSTAHTVTAAVQCGGDVHVLVAGHQCGAAAQAAAQLVGVSKVLVADAAHFADGLAENCAAQVLAIASNYSHILAPATAYGKNILPRVAAILDVAQVSEITKVISADTFERPIYAGNAISTVQSTDAVKVITVRTTGFDSAAAGGSAVVENITAVADSGQSSFVSREVAKSDRPELTAAKIIVSGGRGMGSGENFKLLEPLADKLGAAMGASRAAVDAGYVPNDWQVGQTGKIVAPSLYIAVGISGAIQHLAGMKDSKTIVAINKDPEAPIFSVADYGIVGDLFEIVPQLIAELG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4V5</accession>
    <name>A0A2S9H4V5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0209</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95014">
        <property type="protein sequence ID" value="PRC95014"/>
        <property type="gene ID" value="S2091_0209"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015609418" evidence="1">
        <location>
            <begin position="21"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC95014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="255" mass="28685" checksum="14EC491AB17825DF" modified="2018-07-18" version="1">MNSIFFGGILLYLNLSSAFAQQVQEDMGSVLNEQVQQVSVTGFRDPDWKSYRKMLEGLDAFESNHQLAPSAALQFLLLAKVKSTPIDGLKLKIVGLPNEIDVPISTSHTFVLPRDQSAADNNADLQLNRKKGLFRWRPDIHSPEVPSNARRLGDLRLECEVRWAIDQFDLSFIKIAYIVPLGGACHSSRSKVFYVATKPIIGATLVFGEHREKLDMDRLDSVDHTLYSPPLHDKSWPDNTLIEFEFAESNLTSNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H528</accession>
    <name>A0A2S9H528_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cell wall-active antibiotics response protein (DUF2154)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_0228</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95033">
        <property type="protein sequence ID" value="PRC95033"/>
        <property type="gene ID" value="S2091_0228"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024425">
        <property type="entry name" value="DUF2154"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043726">
        <property type="entry name" value="DUF5668"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09922">
        <property type="entry name" value="DUF2154"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18917">
        <property type="entry name" value="DUF5668"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="18"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="68"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="97"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="domain" description="DUF5668" evidence="3">
        <location>
            <begin position="18"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="domain" description="DUF5668" evidence="3">
        <location>
            <begin position="69"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="domain" description="DUF2154" evidence="2">
        <location>
            <begin position="151"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF18917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC95033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="244" mass="26719" checksum="3C4B8097479DA46F" modified="2018-07-18" version="1">MSKYSGYKRQHRSPQSRLILGVFIVIIGVLSLIDNLGWFDTHQILSFWPVVFIILGVLRISQPRNGSSYFFGVSLLGLGVLLTLQNLGIIAFHWREWWPVLIIAMGISFIFRGVNRNANQSENNGTFLTDSTQINNSDSVEIVAVLSGSKSSNATPNFQGGDINTFMGSVELDLRSASLQNEATIHVFSVFGSVEIRVPNDWVVVLNGTPILGGIEDQSVPPMNSAKRLVISGVVVMGGVEIKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H554</accession>
    <name>A0A2S9H554_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0315</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95120">
        <property type="protein sequence ID" value="PRC95120"/>
        <property type="gene ID" value="S2091_0315"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12802">
        <property type="entry name" value="MarR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00598">
        <property type="entry name" value="HTHMARR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00347">
        <property type="entry name" value="HTH_MARR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50995">
        <property type="entry name" value="HTH_MARR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="1">
        <location>
            <begin position="10"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC95120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="151" mass="16277" checksum="5B7113178C58619E" modified="2018-07-18" version="1">MSNTESPSAALDFCLRLTRATTTINRRLDNALGNLHGLSFSDFTLLLNLSRAPGERMRRVDLAERLGLTVSGITRALIPLEKIGLVTRQSDERDARVGYAVLSKTGKKLLAHALISAEAISQEAVQTASPEQLDAFSLVLGQLAGMNLTNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H568</accession>
    <name>A0A2S9H568_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0324</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95129">
        <property type="protein sequence ID" value="PRC95129"/>
        <property type="gene ID" value="S2091_0324"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC95129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="313" mass="36274" checksum="F665F84395DA4C31" modified="2018-07-18" version="1">MGFNKCIINQRGRSRFTIMMVTLLALAAFTVRAETLIIHPAAESISDPRYRYDWAVLRAAMDETLETFGPYTIQEASERGMVQKRVDYEMQIPTGSINIFVRATSIELEKQFIPIRIPVDRGILSYRVFLVRSADLPRFASVRNLDDLRKFRFGQGKDWVDVRILTSAGFTVIEGTNYDGLFSMLTHARFDVFSRSIDEAFSEYSMQHENHPTMSIEPTLVLHYPLPRYFFVRRNPQGEQFAKRIETGMEMMLRDGSLVKLFFQFKSDQITQAAFAKRTVLNIPNPLLPPETPLSRRELWYDPFDSMPTINKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5L5</accession>
    <name>A0A2S9H5L5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_0426</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DoxX family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95231">
        <property type="protein sequence ID" value="PRC95231"/>
        <property type="gene ID" value="S2091_0426"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032808">
        <property type="entry name" value="DoxX"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07681">
        <property type="entry name" value="DoxX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="69"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="94"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="125"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC95231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="156" mass="17347" checksum="4C0581D58C99D4D5" modified="2018-07-18" version="1">MKNLLKIHQLSTRFDDVITQWGGTLLSLILRCYVAWQFLHAGLIKIQNWPGTLELFHTEYHVPLLPPDLAAYMGAGGELVLPCFLIAGLFSRPAAIGLFFVNAMAVISYPQLWEFECPAGINDHFYWGIILVVIAVFGAGRFSIDALLKNITAKAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GS73</accession>
    <name>A0A2S9GS73_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Helix-turn-helix domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_4736</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000058">
        <property type="protein sequence ID" value="PRC90557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90557">
        <property type="protein sequence ID" value="PRC90557"/>
        <property type="gene ID" value="S2091_4736"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002514">
        <property type="entry name" value="Transposase_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010921">
        <property type="entry name" value="Trp_repressor/repl_initiator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01527">
        <property type="entry name" value="HTH_Tnp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48295">
        <property type="entry name" value="SSF48295"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0814">Transposable element</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="111"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC90557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="175" mass="20528" checksum="02E637AF89467F2E" modified="2018-07-18" version="1">MSKYSKQFKLAVVKRYQEGSTGYKAVAHQYEINHSFVRNWVKQYALHGEAGLDKKFSHYSAEFKLSVLQYMWDKQLSYRETAILFDIRNLNILSNWERSYHSGGIQALIPRTRGRPKAMSPPKKVQPQPAKTDESRSREELLEEVNYLRMENAYLKKLKALVQEQALEASLKKRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSD3</accession>
    <name>A0A2S9GSD3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4659</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000042">
        <property type="protein sequence ID" value="PRC90623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90623">
        <property type="protein sequence ID" value="PRC90623"/>
        <property type="gene ID" value="S2091_4659"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="194" mass="22267" checksum="1F4E09665FE35E27" modified="2018-07-18" version="1">MNKPTNHPHISIPATSTINKEQNTSPRPPRIHLVIGPVGAGKSTFALQLGQDNNAIRLNLDDWMAELFRPDRPDINVMEWYIARTKRCIEQIWKITLNLIGTGADVVLEIGLIQQRDREALYARIDEHGIDLAIYVLDAPRDIRRKRVCQRNAEKGETFSMEVPMQIFELASDMWEPPTEAERSSRSMYFLVTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GST5</accession>
    <name>A0A2S9GST5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Flagellar hook-length control protein FliK</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_4521</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000036">
        <property type="protein sequence ID" value="PRC90773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90773">
        <property type="protein sequence ID" value="PRC90773"/>
        <property type="gene ID" value="S2091_4521"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021136">
        <property type="entry name" value="Flagellar_hook_control-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02120">
        <property type="entry name" value="Flg_hook"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0966">Cell projection</keyword>
    <keyword evidence="3" id="KW-0969">Cilium</keyword>
    <keyword evidence="3" id="KW-0282">Flagellum</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flg_hook" evidence="2">
        <location>
            <begin position="363"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="256"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC90773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="440" mass="46016" checksum="2EB71ECD9259E3B8" modified="2018-07-18" version="1">MVSGVDSPIAQNPLIEASGSVALVNQAKQGAILNSSQLVVGKQFQAEVVTALEDGTYIVKVADIAARMQLPNSPQVGAKLSLTLISTSPRATFLLGSPEDEEAAASSSAASTTSTATLGTVKQLIDDFVQASGNKNTTTTAGLYLQSGANVTAVTNANPDPRLISLATVSPDGTPTTFSSAGKLVDQLLQNTSQQETATVSKVPLLTTPDVNIGVMAKALQSGVTSSGVFYESHLLQWAEGTLNVAELMKEPQANFKSLPENSPTTGTSNTNANAQANTAANSPINANSLIISSANLLSSTATTTQSNSTTNPIASAVITLPPTAAPLIQQQLQTMEQQRFVWHGELWPGQPMEWEISRDQPKQQGETAERTWQSAVRFELPQLGAISAQLQLTGTHLRLSVQAKDAPTALMLQNHAGELVAALDGTGAQLDSLLIKIKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GT45</accession>
    <name>A0A2S9GT45_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Peptidase M15</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4452</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000034">
        <property type="protein sequence ID" value="PRC90871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90871">
        <property type="protein sequence ID" value="PRC90871"/>
        <property type="gene ID" value="S2091_4452"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1380.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009045">
        <property type="entry name" value="Hedgehog_sig/DD-Pept_Zn-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013230">
        <property type="entry name" value="Peptidase_M15A_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08291">
        <property type="entry name" value="Peptidase_M15_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55166">
        <property type="entry name" value="SSF55166"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_M15_3" evidence="1">
        <location>
            <begin position="7"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="151" mass="16432" checksum="54C0C7B2A1B5DD05" modified="2018-07-18" version="1">MTQLSRHFMLSEFTRSATAQARKIDNTAPPAVVKNLFLLAQFIEQVRTELNDAAIFISSGYRCPALNKAVGGAATSSHLTGLACDFTVPHFGTPFAICQQLAKSDLMFDQLIYERTSTAIWAHCGIAASGVTPRRQVLTIDGNGTRVGLWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GT92</accession>
    <name>A0A2S9GT92_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4343</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000032">
        <property type="protein sequence ID" value="PRC90942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90942">
        <property type="protein sequence ID" value="PRC90942"/>
        <property type="gene ID" value="S2091_4343"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC90942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="193" mass="21410" checksum="90F977176E97FD88" modified="2018-07-18" version="1">MTIEQTPQDEDKPQPQKSEITDFAGESRRRFTKAGLAASGVLMTLASRSLLACHEISPSGFSSVNQSTHGTPPASRCRRPYYWAGDCSWPIDKTTKFSSVFRSCTKGSPYYNYTCADVLAGKCTTDTNSYDCVGQYLVAAYLNACMGWSSNFLTTSQCLEMGNEWLQTKVYHPTAIVSWNCNKIVTYLQNVQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTB2</accession>
    <name>A0A2S9GTB2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acetyltransferase (GNAT) domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4360</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000032">
        <property type="protein sequence ID" value="PRC90959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90959">
        <property type="protein sequence ID" value="PRC90959"/>
        <property type="gene ID" value="S2091_4360"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038740">
        <property type="entry name" value="BioF2-like_GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13480">
        <property type="entry name" value="Acetyltransf_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Acetyltransf_6" evidence="1">
        <location>
            <begin position="162"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="347" mass="40123" checksum="98E41498853E57D9" modified="2018-07-18" version="1">MPLTSFQRFRLVDLPPDMFEAWQKIAQDNKAFHSPFFSPYFARAVAEVAKDRCYVTVALQDTTPIGFFPFQFTNSVLGRAERIGLYLSDYNGYISSEKLQPEQLIELLEVSKIHQYSFDHLHEFQAKLGLNTEFIREGTATHLCDGFEAYWAERERISPKFTKDTMRCLHKISKEKGELRFEFHSPDLSDLQSLIQTKRHQYYVTGATDGMASQWANQCLTNLHAVQNKYFRGVLSKLYSGDQLISSHFGLLANGVFHYWFPVYEVSYSAYSPGRLLFYLLTKNAAQFGIACIDNGMGAQRHKSDFANHTYKLGVGTFRRNTARCLVIRAQDYIRYRVLDIRDPIEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTI0</accession>
    <name>A0A2S9GTI0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Zonular occludens toxin (Zot)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_4220</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000030">
        <property type="protein sequence ID" value="PRC91032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91032">
        <property type="protein sequence ID" value="PRC91032"/>
        <property type="gene ID" value="S2091_4220"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008900">
        <property type="entry name" value="Zot_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05707">
        <property type="entry name" value="Zot"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="183"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="domain" description="Zot" evidence="2">
        <location>
            <begin position="1"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="334" mass="37778" checksum="2290FFF2F3BA058E" modified="2018-07-18" version="1">MISLFTGLPGNGKTLYAISHVKEWSEKDSRPVFYSGIELNEELLPWTKIEAEDWHKCPTGSIVVIDECQRVFRPRTISKEIPEYVSKLETHRHLGIDLVLITQHPLLADSSIRRLTGDHRHIIRIWGTANATIHQWGSVKDSCDKTSGRLDSNKTKWRFDKKVYDYYKSAELHTGKTSVPFRIYLVIAAPIAIAFGVWYMYGYTQKQSNPTTELASLNGIAPGASQATVLSYKNGMEEAKQYIYLSTPRFQDLPHTAPKYDELTKPTIAPTPVGCVETKNTCRCFSQQGTPINVSANMCLNIVQNGFFQDFDVNGQQQKDSNQQNNQVSKNDLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTJ4</accession>
    <name>A0A2S9GTJ4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4225</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000030">
        <property type="protein sequence ID" value="PRC91037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91037">
        <property type="protein sequence ID" value="PRC91037"/>
        <property type="gene ID" value="S2091_4225"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="108" mass="11849" checksum="1231B50F7E1D498D" modified="2018-07-18" version="1">MAEPATATQSSNSKIGFMQVAVKGRIESSSSYEGKRATKIMTPAADEYSRPQILEVRSKNRLGENGDLVTLRCTLGGYQRKAYQAKDKESGEIKTVVPVDHTLDVIED</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTP3</accession>
    <name>A0A2S9GTP3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4183</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000029">
        <property type="protein sequence ID" value="PRC91087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91087">
        <property type="protein sequence ID" value="PRC91087"/>
        <property type="gene ID" value="S2091_4183"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021804">
        <property type="entry name" value="DUF3375"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11855">
        <property type="entry name" value="DUF3375"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="489" mass="56185" checksum="DA4ADCE8FD891874" modified="2018-07-18" version="1">MTTLDYTTLTLLRQNHPAWKLLRSDHVPLVASFFQRVFITPNVRIMTQADLVETLEDELFSLREQLGADAFPKAALDYLNDWASNAWLRKFYVQDSDEPHFDLTPATEKSIAWLGALAERSFVGTESRLLTLFDLLKQMNTGSETDPQTRIAELHKQRDQIDAEIIRVSAGDFTLLDDTALKDRFQQFTSIARELLADFREVEHNFRGLDRRVRERVALWNGSKGALLEEIMGERDAISDTDQGKSFRAFWDFLMSSRRQEELSNLLERVLNLTPIAELKPDARIRRIHYDWLEAGEHTQRTVAQLSQQLRRFLDDQAWLENRRIMDILHGIEVKALALRHALPPGEVMSIADTAASIELPMERPLFSPATKTAIANLKLESGEDELNLDSDSAMQALYSQIVIDKHQLAKHIRQTLQDRSQVTLRELCELQPLQHGLAELVAYLQLACDSFNATVDEDIIETVFWSRDTVDGQHIEKQARLPRVIFVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTP7</accession>
    <name>A0A2S9GTP7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltransferase domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4181</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000029">
        <property type="protein sequence ID" value="PRC91085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91085">
        <property type="protein sequence ID" value="PRC91085"/>
        <property type="gene ID" value="S2091_4181"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_11" evidence="1">
        <location>
            <begin position="81"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="263" mass="30136" checksum="83067081F507C418" modified="2018-07-18" version="1">MEEKNNQNCNIDLDAWLKQPSGIYVRAWEQTVLDKLTADIFGFNAVQIGLPQIDCLAASRMPNKWLANDTLLPNSPNKIALLHDFEDLPFDTQSLDLIVLPHVLEFAAEPHQILREVERVLIPEGRLIICGFNGASLWGARQTVGRFSGRYFLPKSAEFISLLRLKDWLKLLNMEVDRGHFGCYAPPLDNQKWLQRFHFMEPAGERWWPYLGAAYIVQAIKRVKGMHLIGPAWKNKRLLVPNAVPVTNRHHSDQLDIPSKLIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTT8</accession>
    <name>A0A2S9GTT8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Luciferase family oxidoreductase, group 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_4122</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">To bacterial alkanal monooxygenase alpha and beta chains.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000028">
        <property type="protein sequence ID" value="PRC91121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91121">
        <property type="protein sequence ID" value="PRC91121"/>
        <property type="gene ID" value="S2091_4122"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011251">
        <property type="entry name" value="Luciferase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036661">
        <property type="entry name" value="Luciferase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019949">
        <property type="entry name" value="Luciferase_OxRdatse_group-1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00296">
        <property type="entry name" value="Bac_luciferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51679">
        <property type="entry name" value="SSF51679"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03558">
        <property type="entry name" value="oxido_grp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bac_luciferase" evidence="2">
        <location>
            <begin position="14"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007789"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="259" mass="27943" checksum="9C453A2F7E123D88" modified="2018-07-18" version="1">MIPLSILDLSPITQGSTAAQSFRNSLDLAQHGERWGYHRYWLAEHHGMPGIASAATAVLIGHVAGGTTRIRVGAGGIMLPNHSPLVIAEQFGTLESLFPGRIDLGLGRAPGSDQVTARALRRNLASDADEFPQDVVELLDYFSAEPKRSVRAVPGTGLNIPIWILGSSLYGAQLAAELGRPYAFASHFAPAQMMQAIELYRATFKPSAQLAKPYVMLGMNVVAADSDEEANYRATSMQQAFVNLRSGRPSTLMKWTPPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTW8</accession>
    <name>A0A2S9GTW8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_4155</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000028">
        <property type="protein sequence ID" value="PRC91154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91154">
        <property type="protein sequence ID" value="PRC91154"/>
        <property type="gene ID" value="S2091_4155"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010559">
        <property type="entry name" value="Sig_transdc_His_kin_internal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06580">
        <property type="entry name" value="His_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="61"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="102"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="domain" description="His_kinase" evidence="2">
        <location>
            <begin position="152"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06580"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="356" mass="39479" checksum="21F9D21B2F7B97D7" modified="2018-07-18" version="1">MGWRRVRVVLIVSVVVGLIWLPIFQSSWVLLLFRLLFVGLVQLLIYGLFERWPQRLPLWLARWVLQVAAVAIVVPFATVFIYSLTTFSTPAVWSLDDKKMLGFGLLTAVGLLVSPWIAMSALYRHINGHAQRQALSFELERSEFARDALDSRLRLLQTQVEPHFLFNTLANVRELVDSGSPQASAVLNSLIAYLRAAVPNLNNASSTLGRELELVRAYLELMHMRMPDRMQFSIDVDEAALKIQCPSMSLLTLVENSVRHGIDPSEDGGQIDVTVRLKDGRCLAQVSDTGIGLAQDAHGNQGSKGLGTGLTNLRERMQLVFSGDAQLSLTARVPHGFNAELNFPAQFESLVSGSKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GU61</accession>
    <name>A0A2S9GU61_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">IscR: iron-sulfur cluster assembly transcription factor IscR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4029</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000026">
        <property type="protein sequence ID" value="PRC91244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91244">
        <property type="protein sequence ID" value="PRC91244"/>
        <property type="gene ID" value="S2091_4029"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003690">
        <property type="term" value="F:double-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010242">
        <property type="entry name" value="TF_HTH_IscR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000944">
        <property type="entry name" value="Tscrpt_reg_Rrf2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33221">
        <property type="entry name" value="PTHR33221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02082">
        <property type="entry name" value="Rrf2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02010">
        <property type="entry name" value="IscR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00738">
        <property type="entry name" value="rrf2_super"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51197">
        <property type="entry name" value="HTH_RRF2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="155" mass="16903" checksum="6003A845DF6CBED4" modified="2018-07-18" version="1">MRLTTKGRFAVTAMIDLALHQNEGPVTLAGISSRQEISLSYLEQLFGKLRRHEIVESVRGPGGGYNLGRAAHKVTVADIIIAVDEPIDATQCGGKENCHSSDHPGGARCMTHELWATLSAKMVDYLDSVSLQDLVNQQTASEQKIIVMHTQQHLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GU75</accession>
    <name>A0A2S9GU75_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Mannose-6-phosphate isomerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4036</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000026">
        <property type="protein sequence ID" value="PRC91251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91251">
        <property type="protein sequence ID" value="PRC91251"/>
        <property type="gene ID" value="S2091_4036"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013096">
        <property type="entry name" value="Cupin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07883">
        <property type="entry name" value="Cupin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cupin_2" evidence="1">
        <location>
            <begin position="39"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="118" mass="13162" checksum="C943432F484D3567" modified="2018-07-18" version="1">MTIKAKISDTNNAEYYIWGEVCDGWHLLKTPDLSVIQERVPPGAGEVRHFHTKARQYFYVLSGQATLEFNDGEISFGANQGVHVEPGVHHRFKNVGDTDVVFMVISSPSTKGDRENLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUS2</accession>
    <name>A0A2S9GUS2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Aminotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_3760</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the DegT/DnrJ/EryC1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000022">
        <property type="protein sequence ID" value="PRC91482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91482">
        <property type="protein sequence ID" value="PRC91482"/>
        <property type="gene ID" value="S2091_3760"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00616">
        <property type="entry name" value="AHBA_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026385">
        <property type="entry name" value="AminoTrfase_NHT_00031"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000653">
        <property type="entry name" value="DegT/StrS_aminotransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30244">
        <property type="entry name" value="PTHR30244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01041">
        <property type="entry name" value="DegT_DnrJ_EryC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000390">
        <property type="entry name" value="PLP_StrS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04181">
        <property type="entry name" value="NHT_00031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="2 3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="194"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="2">
        <location>
            <position position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR000390-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000390-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC91482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="360" mass="39356" checksum="87B90F3089FE917E" modified="2018-07-18" version="1">MHAPTFVGNEKNYVLDCIDSTFVSSVGSYVTRFEQMIADFTGAKYAIATVNGTAALHVALKLVGVNLGDEVITQPLTFIATCNAIAYCGAKPIFVDVNRTTLGICPLSLLNFLTENTTQTELGCINKATGKRIAAVLPMHTFGLPSQIDEIVKICSQFNIPCVEDAAESLGSFYQGQHTGTFGAIATLSFNGNKTITTGGGGMIITNNEALAIRAKHITTTAKLPHKYEFVHDEIGYNYRLPNLNAALGCAQMEVLPRLLASKRVIALAYADFFKDSPYQFITEPAQAHANYWLNAIILNDQRERDAFLNDLNEAGVMSRPIWQLISQLTMFEECQSVELTNARWLAERVVNIPSSAKLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUT9</accession>
    <name>A0A2S9GUT9_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 6">Superoxide dismutase</fullName>
            <ecNumber evidence="2 6">1.15.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_3831</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Destroys radicals which are normally produced within the cells and which are toxic to biological systems.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>2 H(+) + 2 superoxide = H2O2 + O2</text>
            <dbReference type="Rhea" id="RHEA:20696"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:18421"/>
            <dbReference type="EC" id="1.15.1.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the iron/manganese superoxide dismutase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.15.1.1" evidence="2 6"/>
    <dbReference type="EMBL" id="PUGF01000023">
        <property type="protein sequence ID" value="PRC91416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91416">
        <property type="protein sequence ID" value="PRC91416"/>
        <property type="gene ID" value="S2091_3831"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004784">
        <property type="term" value="F:superoxide dismutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.990">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.55.40.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001189">
        <property type="entry name" value="Mn/Fe_SOD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019833">
        <property type="entry name" value="Mn/Fe_SOD_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019832">
        <property type="entry name" value="Mn/Fe_SOD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019831">
        <property type="entry name" value="Mn/Fe_SOD_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036324">
        <property type="entry name" value="Mn/Fe_SOD_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036314">
        <property type="entry name" value="SOD_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02777">
        <property type="entry name" value="Sod_Fe_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00081">
        <property type="entry name" value="Sod_Fe_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000349">
        <property type="entry name" value="SODismutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01703">
        <property type="entry name" value="MNSODISMTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46609">
        <property type="entry name" value="SSF46609"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54719">
        <property type="entry name" value="SSF54719"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00088">
        <property type="entry name" value="SOD_MN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sod_Fe_N" evidence="7">
        <location>
            <begin position="2"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="domain" description="Sod_Fe_C" evidence="8">
        <location>
            <begin position="89"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="27"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="74"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="157"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="161"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000349-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000414"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC91416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="192" mass="22055" checksum="BE9076793DB96815" modified="2018-07-18" version="1">MKHTLPPLPYAMDALEPHISKETLEYHYSKHHQAYITNLNKLLEGSEFESASLEEIIKNASDGLFNNAAQVWNHTFYWNSLSPDSHLKPSGILADAINEKWNSFDKFKEVFTKSCVSNFGSGWTWLIKKADGSLDIVNTSNAATPLTGSDIPLLTCDVWEHAYYIDYRNLRPKYIEAFWELANWDFAEENFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUY9</accession>
    <name>A0A2S9GUY9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major Facilitator Superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_3796</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000022">
        <property type="protein sequence ID" value="PRC91518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91518">
        <property type="protein sequence ID" value="PRC91518"/>
        <property type="gene ID" value="S2091_3796"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="52"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="78"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="103"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="137"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="166"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="217"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="258"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="284"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="307"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="346"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="373"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="14"/>
            <end position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC91518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="407" mass="43445" checksum="E91FD26CDB9C6E5B" modified="2018-07-18" version="1">MQNQDTSLRQDAKVIGLVGLAHSISHFSHLILAPLFPWIKQAFQLSYAELGWLMSVFFIVSGIGQALAGFVVDKIGALKVLCFGLLCLGCSALVLGYASSYPILLLGAMLAGLGNSVFHPADYAILNQRISPKRLAYAFSVHGITGNLGWVCAPLFLVGIASTTNWHSALLAAAILPFSILALLLFNRHFLETKIAKKTAHQVQNQEHVLNFLRLPAVWQCFAFFLIIALALGGIQSFAVASLQSMYAMSLVLATSAYTSYMIASALGMVIGGFLASKTSRHDYIIAWAFLISGSVMWLIATGWLPSWFIVGLMGLVGFGAGIAGPSRDLMIRAAAPKNATGRVYGVVYSGLDSGLALAPLLFGVILDANQPKWVFICIGIFQILALLTAVNVGKRTAHGAGALQAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GUZ9</accession>
    <name>A0A2S9GUZ9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">CobB: cobyrinic acid a,c-diamide synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_3806</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CobB/CobQ family. CobQ subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000022">
        <property type="protein sequence ID" value="PRC91528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91528">
        <property type="protein sequence ID" value="PRC91528"/>
        <property type="gene ID" value="S2091_3806"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042242">
        <property type="term" value="F:cobyrinic acid a,c-diamide synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004484">
        <property type="entry name" value="CbiA_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002586">
        <property type="entry name" value="CobQ/CobB/MinD/ParA_Nub-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011698">
        <property type="entry name" value="GATase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43873">
        <property type="entry name" value="PTHR43873"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01656">
        <property type="entry name" value="CbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07685">
        <property type="entry name" value="GATase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00379">
        <property type="entry name" value="cobB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CbiA" evidence="4">
        <location>
            <begin position="12"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="domain" description="GATase_3" evidence="5">
        <location>
            <begin position="239"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC91528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="438" mass="46276" checksum="A709664CEBB8C153" modified="2018-07-18" version="1">MQEQLQARILLVSAVASGQGKTTVTAALARKLVLQGLRVRVFKTGPDFLDPMLLEIASRAPVYSLDLWMVGLEQCRTQLAEAARVADVILIEGVMGLYDGAPSSADLARAFGVPVLAVVDVSAMAQTCGAVVTGLRDYGPVNLAGVIANRVASPGHAAMVVAALRDIPMLASLSRQEKSLPERHLGLVLPDEVADIESLLDTLAEQLTLDADVWNAISPVQLDQEQAIEQVTSTLAGTTIAIARDAAFAFLYPANLDCLTKLGAKLCFFSPLANQPVPSGANAIYLPGGYPELHAATLSKAMIWQDSIRQAHARDVSIWAECGGMMSLTDSLSDLEGNSWSMAGILPGHVAMQKRLAGLGSQGLTTRHGILRGHTFHYSRLETSVAPISATFKHSSAGTGAVGEAVYKVGSLTASYFHAYFPSCPLAAAMLLTGEMVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GV19</accession>
    <name>A0A2S9GV19_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Hydroxypyruvate isomerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_3667</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the hyi family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000021">
        <property type="protein sequence ID" value="PRC91551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91551">
        <property type="protein sequence ID" value="PRC91551"/>
        <property type="gene ID" value="S2091_3667"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026040">
        <property type="entry name" value="HyI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036237">
        <property type="entry name" value="Xyl_isomerase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013022">
        <property type="entry name" value="Xyl_isomerase-like_TIM-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01261">
        <property type="entry name" value="AP_endonuc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006241">
        <property type="entry name" value="HyI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51658">
        <property type="entry name" value="SSF51658"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AP_endonuc_2" evidence="3">
        <location>
            <begin position="21"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="2">
        <location>
            <position position="143"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="2">
        <location>
            <position position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR006241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR006241-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC91551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="262" mass="29359" checksum="137FED80B20D6575" modified="2018-07-18" version="1">MPRFAANLSMMYPEFTFVERFAAAAHDGFKAVEFQFPYEFPAAQINTLLADNNLTLALFNAPPGNWANGERGLASLPNRINDFKHSIDQALNYAHILGNKKLHVMAGLIQPDSDSGAQRNVYLNNLAYAAELAQQAGINLVIEPINTRDMPSYFLNQQEQAQAICTELALPNVQVLFDIYHCQIMEGDLATKLRRDMQRNNAGIGHIQIAGAPDRHEPDLGEINYPYLFELIDALGYTGWIGCEYRPRNNTSAGLTWLKSWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GV73</accession>
    <name>A0A2S9GV73_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Inward rectifier potassium channel</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">S2091_3735</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000021">
        <property type="protein sequence ID" value="PRC91619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91619">
        <property type="protein sequence ID" value="PRC91619"/>
        <property type="gene ID" value="S2091_3735"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005242">
        <property type="term" value="F:inward rectifier potassium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034765">
        <property type="term" value="P:regulation of ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1400">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041647">
        <property type="entry name" value="IRK_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013099">
        <property type="entry name" value="K_chnl_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016449">
        <property type="entry name" value="K_chnl_inward-rec_Kir"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013518">
        <property type="entry name" value="K_chnl_inward-rec_Kir_cyto"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11767">
        <property type="entry name" value="PTHR11767"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07885">
        <property type="entry name" value="Ion_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17655">
        <property type="entry name" value="IRK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01320">
        <property type="entry name" value="KIRCHANNEL"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="SSF81296"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10 14" id="KW-0407">Ion channel</keyword>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0630">Potassium</keyword>
    <keyword evidence="3" id="KW-0633">Potassium transport</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <keyword evidence="5" id="KW-0851">Voltage-gated channel</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="44"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="78"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="107"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="domain" description="Ion_trans_2" evidence="12">
        <location>
            <begin position="58"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="domain" description="IRK_C" evidence="13">
        <location>
            <begin position="138"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF07885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF17655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="PRC91619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="299" mass="34531" checksum="7D43DAE12F7C7AAB" modified="2018-07-18" version="1">MHKSAKSRTTHPFKIEDRLFVAHGLSSQFWQDIYHYAMTSSWPVFFGAFSLMFGSMNVFFACLYMLGDHPIGNLFPNGFWGAFFFSVETLATVGYGDMHPQTVYGHLVSTIEIFIGMSGLAMVTGVIFARFSLPKSKILFTKHPVSHMHDNRYMLSIRIANTRLNIISEASAKLRMMRLETTAENTKFLRLIDLPLQRSQHPLFTLGWNLFHEINEDSPFFNLSSEEMERDQVRLILSLEGIDDTTSQAIRAHHIYSHDKIRLHHRYVDIHYQDADLVSHVDYARFHEIVPMPQAAEKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVJ2</accession>
    <name>A0A2S9GVJ2_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Thiol:disulfide interchange protein DsbA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_3500</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the thioredoxin family. DsbA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000019">
        <property type="protein sequence ID" value="PRC91745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91745">
        <property type="protein sequence ID" value="PRC91745"/>
        <property type="gene ID" value="S2091_3500"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03019">
        <property type="entry name" value="DsbA_DsbA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001853">
        <property type="entry name" value="DSBA-like_thioredoxin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023205">
        <property type="entry name" value="DsbA/DsbL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01323">
        <property type="entry name" value="DSBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0574">Periplasm</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015747116" description="Thiol:disulfide interchange protein DsbA" evidence="5">
        <location>
            <begin position="32"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="6">
        <location>
            <begin position="19"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC91745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="220" mass="24586" checksum="2F6D3FA23C273DBA" modified="2018-07-18" version="1">MHNTNPARRAAITKLAIGLTGAWLAPQLVLAQEQFVAGKDYQAIATPFATEVAAGKIEVREFFGYWCPHCNAFDPHLNEWAGKQKSDVALTHTPWAWQESQIPFQRLFYALEVAGKEKELRSKVFESMFKDHLRLESVDAQVDWASKHGIDAQQFRALLDSFSVVTNLRKGTQLAKTAGIKGVPSLVINGKYLVTNDDNPLGTMDYLINLERKLASNKAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVN0</accession>
    <name>A0A2S9GVN0_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_3529</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="PUGF01000019">
        <property type="protein sequence ID" value="PRC91774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91774">
        <property type="protein sequence ID" value="PRC91774"/>
        <property type="gene ID" value="S2091_3529"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="15"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="48"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="6">
        <location>
            <begin position="229"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="193"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC91774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="469" mass="52299" checksum="669D8418EA268BD9" modified="2018-07-18" version="1">MMKITPNKVSLGKQLFLVFGATALLMICFETVKTLLFGSRLTLWQSHLMTIFVTALIGAAVFVVLKMYTAKYEDINKELAELLKFNESILFNSPLPMAVYAPNGRCVEVNEAYAHIFTLTRASMLQYHNNSVFEACGLLEKFTAVLIEGVGQRCEIHDTNLFGREVWFDCEILPMQINGKNHVLVQFYDFTQRKRAEEKLVAINNELQAAMRRLVQAEKMAALGTLVAGVAHELNTPIGNALMAASTLNVHVQELSASVNTGTLKRSALVTYVENTIDEASLIERNIIRAADLVRNFKQVAVDQASERRRHFDLQRVITDIISTMRPTLSKSSHVLKVYIEENIQLDSYPGSIEQIVTSFINNALVHAFAHKESGNMLLHARRDNEYVLLEFSDDGEGMCDEVAMHAFDPFFTTRMGVGGSGLGLYIVNNIVTDILGGNIMLTTSPGHGAHFQLRLPLVAPERSTARLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVP2</accession>
    <name>A0A2S9GVP2_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF1801 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3550</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000019">
        <property type="protein sequence ID" value="PRC91795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91795">
        <property type="protein sequence ID" value="PRC91795"/>
        <property type="gene ID" value="S2091_3550"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014922">
        <property type="entry name" value="DUF1801"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08818">
        <property type="entry name" value="DUF1801"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF1801" evidence="1">
        <location>
            <begin position="23"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="205" mass="23365" checksum="F5EB24DD46DD2609" modified="2018-07-18" version="1">MPTPKYNPKVDAYTETVEDFAKPILVHLRALIHATCPEVIEEVKWGNPHFDYKGDMMCIFAAYKKHCSFTFYKDSLMGDARLKANAGISAAKRFMGKLTNVADLPPDRELKSWIKESMALNEQGVKLPARESKTPKDVEIPAAFAEKLQANPKIIKIFESKSASFQKEYNVWIGEAKTEATRDKRIEEAMAWIVEGKGRFWKYAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVQ7</accession>
    <name>A0A2S9GVQ7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Heavy metal translocating P-type ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_3545</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000019">
        <property type="protein sequence ID" value="PRC91790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91790">
        <property type="protein sequence ID" value="PRC91790"/>
        <property type="gene ID" value="S2091_3545"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019829">
        <property type="term" value="F:ATPase-coupled cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.620.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045800">
        <property type="entry name" value="HMBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027256">
        <property type="entry name" value="P-typ_ATPase_IB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012348">
        <property type="entry name" value="RNR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011017">
        <property type="entry name" value="TRASH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007029">
        <property type="entry name" value="YHS_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19335">
        <property type="entry name" value="HMBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04945">
        <property type="entry name" value="YHS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00746">
        <property type="entry name" value="TRASH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="SSF47240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="SSF81653"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="SSF81665"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01525">
        <property type="entry name" value="ATPase-IB_hvy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-1278">Translocase</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="194"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="225"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="255"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="294"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="447"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="475"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="787"/>
            <end position="809"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="815"/>
            <end position="834"/>
        </location>
    </feature>
    <feature type="domain" description="TRASH" evidence="7">
        <location>
            <begin position="26"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="domain" description="TRASH" evidence="7">
        <location>
            <begin position="88"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC91790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="841" mass="90362" checksum="52CC88B93ACFB4D7" modified="2018-07-18" version="1">MTESSSSCCASNNATTTQAVTAGLIDPVCGMDVAKDSPHQQRYQGIKYYFCSNSCLNKFDANPTAYVKKRAITIKAPTTASNQAGLKDPVCGMSVASTSQHSVLYQDQTYYFCCAGCATKFKAKPDFYLNPPPPTEPTADQKNSLYSCPMHPEVEQIGPGTCPLCGMALDPMEVSSEIDSSELDDFTHRFKWSLVFTLPLLILTMGDMVFGMTFSHLLGHSVFNYLQLLLASPVVLWIAKPFFERAINSFHNRHLNMFSLIGLGVATAYLYSLGVLLFPALLPAEFKTGGMLPLYFEAAAVIITLVLLGQILELRGRARTQNALQALLALTPNVATRVNPDGSDEQINLDLVMPDDLLRVKPGAQIPVDGVLTEGASWVDEAMLTGEAMPQEKTQGSKVSAGTINQTGSFVMQAQKIGRDTLLANIILLVNQASRSRANIQQLADKVAGWFVPFVIVSAIASATVWLLFGAGIPFALMCAISVLLIACPCALGLATPISITVAIGRAASAGVLIKEANSMEQMAKVTTLVIDKTGTLTEGKPRLQQIQTFAEYSRDDVLRYAAALENASEHPLARAIVKAAQEDKLTLPAVIDFQSVTGLGVRGICEGRSLLIGSPQFLQQEKFDLSQLQIQLQTQQNFSVVCIAIDGHLAAAFYLADTLKENTQQILQELRQAGLEIILLTGDNLGSAATIAEQCGINTVHAGLLPADKHRHVEALQKQGKLVAMAGDGINDAPALSQANVGIAMGNGSDIAMQSADIILLKGDLRGILRARQLSLSTIKNIRQNLFFAFIYNFAGVPVAAGLLYPWFGLLLSPMIAAAAMSLSSVTVISNALRLGWIKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVQ8</accession>
    <name>A0A2S9GVQ8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3546</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000019">
        <property type="protein sequence ID" value="PRC91791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91791">
        <property type="protein sequence ID" value="PRC91791"/>
        <property type="gene ID" value="S2091_3546"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="64" mass="7193" checksum="E30BB2FCD0C05FE7" modified="2018-07-18" version="1">MTVMEFTTGSLRFILSWLSCPTIDGRIPLQLAAGFLIVMFGYNYSRLFFVGLAVCIDGSILLRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVY0</accession>
    <name>A0A2S9GVY0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3372</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000018">
        <property type="protein sequence ID" value="PRC91816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91816">
        <property type="protein sequence ID" value="PRC91816"/>
        <property type="gene ID" value="S2091_3372"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="295" mass="32912" checksum="FB6BFA7B31E7D08C" modified="2018-07-18" version="1">MDKLRSMEVFVGVVDAGSFSAVARAFDMSTVMVGKYIADLEQRLGARLLNRTTRRQSLTEIGELYCEQCRQILAQVSIAESGAEAMRATARGTLKVSAPVAFGSECLAPAMATYLEQYPDVSMDLELSNRLSDVVEEGLDAAVRIGQLDDSAMIARPLRPYKMVICASAAYLERFGTPKTPDDLAQHQCLDFLHWRRHVRWRLNQPDAAATLPASRFRSNNGQALKQAALAGVGIMMQAEIVLADDIQRGRLIPILEEFIPIPRPMHLIYPRDRQPTPKLTTFIEFVVERFGVER</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GW14</accession>
    <name>A0A2S9GW14_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Multidrug resistance efflux pump</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_3456</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000018">
        <property type="protein sequence ID" value="PRC91900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91900">
        <property type="protein sequence ID" value="PRC91900"/>
        <property type="gene ID" value="S2091_3456"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="domain" description="HlyD_D23" evidence="3">
        <location>
            <begin position="39"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="143"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC91900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="323" mass="35128" checksum="61E8A50A5AFE246F" modified="2018-07-18" version="1">MKKIHFIGAVIGLVVVTLLGIGLFQSTKPVAPVFQGQIEAREIDVAPKLPARVAYLDVHEGDQVEIGQVLLRLDSPEVAAKLQQANAVKDAAEALRDKANNGARPEERKMAELNWQRADAAAQLAKVSFERVNNLYKEGLLSQQKRDEAQTQWQTSQDAANAARAQADMANQGARIEDRAAASAQARQTAGVLAEVEAAQAETQLKAPVAGEVAKVLIRAGELAPTGVPLITIVDLSDTWMVLNVRETYLQRFAKGQEFDATIPALGNKIARFKVRTNAVLPDFATWRATRSNAGYDVRTFEIKAYPVNKVDGLRPGMSVLIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GW18</accession>
    <name>A0A2S9GW18_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Outer membrane efflux protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3457</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000018">
        <property type="protein sequence ID" value="PRC91901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91901">
        <property type="protein sequence ID" value="PRC91901"/>
        <property type="gene ID" value="S2091_3457"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015562">
        <property type="term" value="F:efflux transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003423">
        <property type="entry name" value="OMP_efflux"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02321">
        <property type="entry name" value="OEP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="222"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="475" mass="52699" checksum="6CE00A31AF0485A5" modified="2018-07-18" version="1">MRIAYHLNRFSLHLYQGTSAALLTAIFINTNSIAATPFNFEQAQQQLFARGGDIVAAKAEIRSKELLTESLQSLDYPRISLAVTALEYKQHLGINLSSITDLLNDPLAGLPMPPLTTLLPDSFDYTLRGSLVSKNVSMFWPLYTGGKITATQNLAKATISQAESELHHTKEQLVSVLVQRYFGLQLARQAAQTRADVVAGVMENDHAAMRMEQQGVISRLERLQVQAALSDAQRNAAKARRDAEIAEVALRHMLASDIEVEPQTALFVISAALEPLHDFIQTALAQHPGLGIIAAKRDQASQLLAIEKASYLPTVTLLGRYEVAPVDRADWIVGLSVRVPLFNNIDRRTSVGAAEQLVIKADALKEQALLNIETLIERNYRLMEQAREQYLMMAENEALAKEALRLRKVGLKQGTGTVLEIIEEQLNLAKVQTERSQASYDFVVELANLLEASGQSERFSEYARRADIRITRENS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GW30</accession>
    <name>A0A2S9GW30_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cytochrome c</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_3422</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000018">
        <property type="protein sequence ID" value="PRC91866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91866">
        <property type="protein sequence ID" value="PRC91866"/>
        <property type="gene ID" value="S2091_3422"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00034">
        <property type="entry name" value="Cytochrom_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0349">Heme</keyword>
    <keyword evidence="3 4" id="KW-0408">Iron</keyword>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cytochrome c" evidence="5">
        <location>
            <begin position="57"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="5">
        <location>
            <begin position="155"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC91866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="247" mass="25565" checksum="518CE19BBACF40A4" modified="2018-07-18" version="1">MSMSTIFGLGSRTRKGVFATKQNLSMASWSLPPLSSLKTYAALTCFVSLFTAHSGSASAADGKALFSTTCIACHGSKGEGNTVIGAPNIAGMDAPYLTRQLSNFSAGIRGTAASDNYGAQMRAAVAVLKSDADRVAVASYVASLPKIKATSTFKANLTNGSTQFNAVCSSCHGSRAQGNTQMGAPALPGTDPVYLERQITAFRSGTRGAHKDDKTGGLMRVGANMLPDALSVHDVVGYINTLNTVKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GW50</accession>
    <name>A0A2S9GW50_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">ATP synthase subunit beta</fullName>
            <ecNumber evidence="12">7.1.2.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">ATP synthase F1 sector subunit beta</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">F-ATPase subunit beta</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">atpD</name>
        <name evidence="14" type="ORF">S2091_3273</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>ATP + 4 H(+)(in) + H2O = ADP + 5 H(+)(out) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:57720"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="7.1.2.2"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Cell membrane</location>
            <topology evidence="12">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 12">Belongs to the ATPase alpha/beta chains family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.1.2.2" evidence="12"/>
    <dbReference type="EMBL" id="PUGF01000017">
        <property type="protein sequence ID" value="PRC91931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91931">
        <property type="protein sequence ID" value="PRC91931"/>
        <property type="gene ID" value="S2091_3273"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045261">
        <property type="term" value="C:proton-transporting ATP synthase complex, catalytic core F(1)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1140.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01347">
        <property type="entry name" value="ATP_synth_beta_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017691">
        <property type="entry name" value="Alt_ATPase_F1_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005722">
        <property type="entry name" value="ATP_synth_F1_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020003">
        <property type="entry name" value="ATPase_a/bsu_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004100">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036121">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000194">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_nucl-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024034">
        <property type="entry name" value="ATPase_F1/V1_b/a_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00006">
        <property type="entry name" value="ATP-synt_ab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02874">
        <property type="entry name" value="ATP-synt_ab_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50615">
        <property type="entry name" value="SSF50615"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03305">
        <property type="entry name" value="alt_F1F0_F1_bet"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01039">
        <property type="entry name" value="atpD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00152">
        <property type="entry name" value="ATPASE_ALPHA_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 12" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="6 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 12" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10 12" id="KW-0139">CF(1)</keyword>
    <keyword evidence="5 12" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="8 12" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 12" id="KW-1278">Translocase</keyword>
    <keyword evidence="2 12" id="KW-0813">Transport</keyword>
    <feature type="domain" description="AAA" evidence="13">
        <location>
            <begin position="147"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="155"/>
            <end position="162"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="PRC91931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="485" mass="52727" checksum="230EE99285D72E31" modified="2018-07-18" version="1">MTTSTSAPNIGTILSVRGSVVDIRFENRLPPINTLLHVNAQVQIAVEVWAQLDAYSVRGIALTPTQGLARGMPVTDTGGPLTTPVGKGTLSRMFDVFGNAIDRGPVLSDVSWRSVHRSPPPLAQRSTQSEIFETGIKVIDVLVPLERGGKAGLFGGAGVGKTVLLTEMIHNVVGHHDGVSIFCGIGERCREGEELYHDMKDAGVLPNMVMVFGQMNEPPGSRFRAGHVALTMAEYFRDDEHRDVLLLIDNVFRFIQAGSEVSGLMGQMPSRLGYQPTMATELAGLEERIANTATGAITSIQAVYVPADDFTDPAAVHIFSHLSASIVLSRDRASEGLFPAIDPLQSNSKMATPGIIGDRHYRLAQEIRHTLAQYSELKDIISMLGLEQLSQDDRNVVARARRLERFLTQPFFTTEQFSGVSGKTVSLKDALDGCERILNDEFKDVPESALYMIGAIDEVKMAAKPTVEVKPIAKLTPEPEMVHAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GW59</accession>
    <name>A0A2S9GW59_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3301</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000017">
        <property type="protein sequence ID" value="PRC91959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91959">
        <property type="protein sequence ID" value="PRC91959"/>
        <property type="gene ID" value="S2091_3301"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010239">
        <property type="entry name" value="CHP02001"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09694">
        <property type="entry name" value="Gcw_chp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02001">
        <property type="entry name" value="gcw_chp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015534789" evidence="1">
        <location>
            <begin position="24"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="254" mass="27314" checksum="B0BB9FDC8674C237" modified="2018-07-18" version="1">MKNKLGSFTAVFFFAVLSHNAIADEVVEAPKPDNEFSFNLGATSDYRYRGISQSNLHPAIQGGADYTNNPTGLYAGTWLSSIKWITDAGGSGDVEMDLYAGKRGDIVSDLSYDVGVLSYVYPGNNLGQIAGLANANTTEIYGQLTYKLANIKYSRSVTNLFSIPGSKNSGYVDLWTSIPVTDALALGLHVGHQTVENNSNFSYTDWKVGLSQDFFGVSFTLGVVGTDANKLMYVTPDGKFTGKTSLVLSAAKTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GW61</accession>
    <name>A0A2S9GW61_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Sulf_transp domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_3307</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPF0394 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000017">
        <property type="protein sequence ID" value="PRC91965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91965">
        <property type="protein sequence ID" value="PRC91965"/>
        <property type="gene ID" value="S2091_3307"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007272">
        <property type="entry name" value="Sulf_transp"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04143">
        <property type="entry name" value="Sulf_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="81"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="112"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="144"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="184"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="221"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="254"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="292"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="domain" description="Sulf_transp" evidence="8">
        <location>
            <begin position="25"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC91965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="317" mass="33743" checksum="E8F0A214E64C38A6" modified="2018-07-18" version="1">MSMITPLFFILALLAAGVMGFAIQRGATCSVTAVDEIVSRRGTKRLVALLEAAVWVAVGLGLAQHFHLLNSLPGGYAVTSWTFFGAMILGLGAYINGACVVGVIARLGIGQWVFALTPIGYFLGCLSMQVIFGMPMHTATPSTSAMALAASAALWPLAALLIWRIYKIFTRTRQANSDTAWSPHMATIVIGFAFLATVILSEKWTYTEVLSELAHGMLQNINGRIGMAAALFAGAVVGGKTAGKFCWTTPSITAALRCLLGGAMMAWGSLLIPGSNDGLILIGMPLLWPYAWLAFFTMCLSIASAQLATRYFFNSQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GW92</accession>
    <name>A0A2S9GW92_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">PEP-CTERM protein-sorting domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3322</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000017">
        <property type="protein sequence ID" value="PRC91980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91980">
        <property type="protein sequence ID" value="PRC91980"/>
        <property type="gene ID" value="S2091_3322"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013424">
        <property type="entry name" value="PEP_exosort_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07589">
        <property type="entry name" value="PEP-CTERM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02595">
        <property type="entry name" value="PEP_exosort"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015436222" evidence="1">
        <location>
            <begin position="28"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="domain" description="PEP-CTERM" evidence="2">
        <location>
            <begin position="203"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="230" mass="23351" checksum="94ACCB49CC8618EF" modified="2018-07-18" version="1">MKSFLRPCLLASMVIGGLATISSTAMATPSICDGVSGNLVSNCGFEGGTYSSTIGGNTNNSVPNNWLPSAGYDLEPSFNHTITAPPLVNSGTTALSIGNDDGQPVPTLSQTLTDVSGSTYNGSVYVLYGAAGTSDTNVFFDLSINGSDLVALNNTASGANTQYTFSFVGTGSDLLTLGGNTSPSEWYVDDVVVTGQAASTPPSVPEPGTLFLAGLGLLALAAGHRKAKKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GW95</accession>
    <name>A0A2S9GW95_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">/NonD: hydrolase CocE/NonD family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3339</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000017">
        <property type="protein sequence ID" value="PRC91997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91997">
        <property type="protein sequence ID" value="PRC91997"/>
        <property type="gene ID" value="S2091_3339"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008239">
        <property type="term" value="F:dipeptidyl-peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005674">
        <property type="entry name" value="CocE/Ser_esterase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000383">
        <property type="entry name" value="Xaa-Pro-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013736">
        <property type="entry name" value="Xaa-Pro_dipept_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02129">
        <property type="entry name" value="Peptidase_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08530">
        <property type="entry name" value="PepX_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00939">
        <property type="entry name" value="PepX_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="SSF49785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00976">
        <property type="entry name" value="NonD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015587306" evidence="1">
        <location>
            <begin position="25"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="domain" description="PepX_C" evidence="2">
        <location>
            <begin position="382"/>
            <end position="650"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="656" mass="73098" checksum="75030312B8A6F192" modified="2018-07-18" version="1">MHTLNRPLALLALSISLIAGFANASDNNLADSGLAEISDSPTVNLREHYTKYEFQIPMRDGVHLFTAVYVPKDASKSYPFLLKRTPYSAGVNAQGELNYGVDYFPSAIGPSPEFEASGYIFVNQDVRGRYMSEGKWQEMTPHVNPKREKGEGNESEDMYDTVEWLLKHVPNNNGKVGILGTSYPGFYTSASIINSHPAIKAASPQAPVTDLYMNDDSYHGGAFMLAANFDFYSTFTEQKNPTPLPKSRTAFNYGTSDGYEFFLSHFTMQDALATLTQNQRALLQPTIEHATYDDFWKIRNIAPHLKNIHAAVLTVGGWFDAEDLQGPLSTYKAIKRNNIGIYNGLVMGPWSHGAWGRLDGASLGNVKFDAKTSLYFRKNILFPFFEQYLKGITNKNTSEVYAFETGTNIWRNYAAWPPQQAQARTLYFGANGTLSWQAPSADSGSAFDEYVSDPKKPVPYIAYVATGVPKEYMVSDQRFAASRPDVLVYRSEPLEQDVTLVGPVSPKLFVSTTGTDADWVVKLIDVYPSEYPNTDSAKGSGKDVAPPSVSMAGYQQLVRGDPLRGKFRNSFEKPEPFTPGKVEVVSYSMSDINHTFRRGHRIMVQVQSSWFPLVDLNPQTFVDIPHAKPEDFQKATQRVFHTTAMPSGIVLQMLPM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWF6</accession>
    <name>A0A2S9GWF6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Pro-kumamolisin, activation domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_3188</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
        <text evidence="6">Binds 1 Ca(2+) ion per subunit.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000016">
        <property type="protein sequence ID" value="PRC92053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92053">
        <property type="protein sequence ID" value="PRC92053"/>
        <property type="gene ID" value="S2091_3188"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04056">
        <property type="entry name" value="Peptidases_S53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11377">
        <property type="entry name" value="Pro-peptidase_S53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015366">
        <property type="entry name" value="S53_propep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030400">
        <property type="entry name" value="Sedolisin_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09286">
        <property type="entry name" value="Pro-kuma_activ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00944">
        <property type="entry name" value="Pro-kuma_activ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="SSF52743"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51695">
        <property type="entry name" value="SEDOLISIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0106">Calcium</keyword>
    <keyword evidence="3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1 6" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0720">Serine protease</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5016306840" evidence="7">
        <location>
            <begin position="29"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S53" evidence="8">
        <location>
            <begin position="207"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="6">
        <location>
            <position position="279"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="6">
        <location>
            <position position="283"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="6">
        <location>
            <position position="468"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="509"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="510"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="523"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="525"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC92053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="705" mass="73074" checksum="94988A681D2F57AE" modified="2018-07-18" version="1">MSRNQGVLIKMRPLAFVIAATFAVSAQAGTTSTWVPTATKSYLNTHPARASAMAQQVMELSAGAPVQIAVSLKLRNKGVLNALSASIGAGGKQYLTPTQFAAQFGPTQAQANVVVSYLQAAGFRNVTVAPNRMLVTADGNAATVKTAFNTTLISYAKNGRQVYVNAGDAMVPQVLADVVLAVHGLQTADLLLPLTQRVSSKLQMQAVVAGHNGTDFSTMYDADSLPAATNISIAIIAQGDISQSLIDLNAFASQSGYPVVSTQEVDTGTKTSDTTGTDEWDLDSQSALAAAGGSVKKMIFYVAPTLADSDLAIAFNRAVTDNLAKTIIVALGECESIAQANGSMATEDQIFQQAMVQGQVFSVGAGDVGSQECPAPSTGQSYPATSPYVIAVGGTTLNSTGTVYASETVWSGSGGGASIIEPAQSWQVNAGVLTGSNRGVPDISFDADPNSGFMVMSSGVPTLIGGTSLSAPLFAGFWARIQSAHGNAVAFPASLFYSNNAAVLAVYHDVTSGSNGAATAKAGWDYASGWGSMDVAKVNALISTAPPPPPPPPTSIIVNGGFESGSTGWNDATGDIGIWSNEPAFAGSYDAWMGGIINSNENLYQKITIPAAAKSANLAFYLHIDTQESGAKAYDMLYVQVRNTSGTLLQTLATFSNANAASGYQLHSYDLSAYKGQAIEIYFNSTNDHEYPTSFVIDNVSVTAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWJ5</accession>
    <name>A0A2S9GWJ5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3228</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000016">
        <property type="protein sequence ID" value="PRC92093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92093">
        <property type="protein sequence ID" value="PRC92093"/>
        <property type="gene ID" value="S2091_3228"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="45"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="104" mass="11309" checksum="BEF453BDF91EECC1" modified="2018-07-18" version="1">MPSKKPMSDKELVAWESSRDIAAELEQSINEMLTGQGKAIVITPVAEVRLQTGLSQSLFAKLLGVSVRTLQEWEQGRRKPSGAAQTLITIAQLHPEILAELAAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWW0</accession>
    <name>A0A2S9GWW0_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">30S ribosomal protein S2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpsB</name>
        <name evidence="6" type="ORF">S2091_3062</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the universal ribosomal protein uS2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92146">
        <property type="protein sequence ID" value="PRC92146"/>
        <property type="gene ID" value="S2091_3062"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01425">
        <property type="entry name" value="RPS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00291_B">
        <property type="entry name" value="Ribosomal_S2_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001865">
        <property type="entry name" value="Ribosomal_S2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005706">
        <property type="entry name" value="Ribosomal_S2_bac/mit/plastid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018130">
        <property type="entry name" value="Ribosomal_S2_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023591">
        <property type="entry name" value="Ribosomal_S2_flav_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12534">
        <property type="entry name" value="PTHR12534"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00318">
        <property type="entry name" value="Ribosomal_S2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00395">
        <property type="entry name" value="RIBOSOMALS2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52313">
        <property type="entry name" value="SSF52313"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01011">
        <property type="entry name" value="rpsB_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00962">
        <property type="entry name" value="RIBOSOMAL_S2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC92146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="250" mass="27526" checksum="432EC753DAA6CB5A" modified="2018-07-18" version="1">MSVTMREMLEAGVHFGHQTRFWNPKMAPFIFGHRNKIHIINLEKTLGLYQEAMKFIRQTSANRGTILMVGTKRQARELIASEAQRAGMPFVDQRWLGGMLTNFKTVKTSIKRLKDMEAQVQEGTVEKLSKKEALMFDREMTKLQKAIGGIKDMGGVPDAIFVVDVGYHKGAITEAAKLGIPVIGVVDTNHSPDGVQFIIPGNDDSSKAIALYARGVADAILEGRANALNEVVELVKAGGDDFVEVNNEQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GWY3</accession>
    <name>A0A2S9GWY3_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 4">Phosphate acyltransferase</fullName>
            <ecNumber evidence="3 4">2.3.1.274</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Acyl-ACP phosphotransacylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Acyl-[acyl-carrier-protein]--phosphate acyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Phosphate-acyl-ACP acyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">plsX</name>
        <name evidence="5" type="ORF">S2091_3127</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 4">
            <text>a fatty acyl-[ACP] + phosphate = an acyl phosphate + holo-[ACP]</text>
            <dbReference type="Rhea" id="RHEA:42292"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="Rhea" id="RHEA-COMP:14125"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:59918"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:138651"/>
            <dbReference type="EC" id="2.3.1.274"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Lipid metabolism; phospholipid metabolism.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer. Probably interacts with PlsY.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="4">Associated with the membrane possibly through PlsY.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the PlsX family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.274" evidence="3 4"/>
    <dbReference type="EMBL" id="PUGF01000015">
        <property type="protein sequence ID" value="PRC92211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92211">
        <property type="protein sequence ID" value="PRC92211"/>
        <property type="gene ID" value="S2091_3127"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00085"/>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043811">
        <property type="term" value="F:phosphate:acyl-[acyl carrier protein] acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00019">
        <property type="entry name" value="PlsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003664">
        <property type="entry name" value="FA_synthesis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012281">
        <property type="entry name" value="Phospholipid_synth_PlsX-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30100">
        <property type="entry name" value="PTHR30100"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02504">
        <property type="entry name" value="FA_synthesis"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002465">
        <property type="entry name" value="Phsphlp_syn_PlsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00182">
        <property type="entry name" value="plsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="4" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="4" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC92211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="368" mass="39427" checksum="FB916D5B76BB8FDC" modified="2018-07-18" version="1">MTIRISIDCMGGDHGPAVTVAAAVSFVKRTEDVQMILVGQENIIRSELKKLKFDHHSRFPFISIVHASEVVTMEDPLEVALRRKKDSSMRVAINQIKDEQADVCVSAGNTGALMAISRYVLKTLPNVDRPAICSILPNQKNKPTYMLDLGANVDCEPRHLQQFAIMAAALFSAVEGTAMPTVGLLNVGEEDIKGNDVVKKTAQLLRDEHAKGVINFYGNVEGNDIFAGTTDIVVCDGFVGNVTLKAAEGLGRFVKTVLNAEFKRNFITMLGALIARSALKAVGSRLNPSNYNGGSLLGLRGLVIKSHGGADAYSFEWAIQRAYDAAKNGVLEHIASAMNELVAQPVSESVAGAIDVSSETPLGETGTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXD4</accession>
    <name>A0A2S9GXD4_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Molybdopterin synthase catalytic subunit</fullName>
            <ecNumber evidence="4">2.8.1.12</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">MPT synthase subunit 2</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Molybdenum cofactor biosynthesis protein E</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Molybdopterin-converting factor large subunit</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Molybdopterin-converting factor subunit 2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">S2091_3030</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>2 [molybdopterin-synthase sulfur-carrier protein]-C-terminal Gly-NH-CH2-C(O)SH + cyclic pyranopterin phosphate + H2O = 2 [molybdopterin-synthase sulfur-carrier protein]-C-terminal Gly-Gly + 4 H(+) + molybdopterin</text>
            <dbReference type="Rhea" id="RHEA:26333"/>
            <dbReference type="Rhea" id="RHEA-COMP:12160"/>
            <dbReference type="Rhea" id="RHEA-COMP:12202"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58698"/>
            <dbReference type="ChEBI" id="CHEBI:59648"/>
            <dbReference type="ChEBI" id="CHEBI:90619"/>
            <dbReference type="ChEBI" id="CHEBI:90778"/>
            <dbReference type="EC" id="2.8.1.12"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; molybdopterin biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the MoaE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.12" evidence="4"/>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92371">
        <property type="protein sequence ID" value="PRC92371"/>
        <property type="gene ID" value="S2091_3030"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00344"/>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030366">
        <property type="term" value="F:molybdopterin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006777">
        <property type="term" value="P:Mo-molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00756">
        <property type="entry name" value="MoaE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1170.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036563">
        <property type="entry name" value="MoaE_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003448">
        <property type="entry name" value="Mopterin_biosynth_MoaE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02391">
        <property type="entry name" value="MoaE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54690">
        <property type="entry name" value="SSF54690"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005426"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00026066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00029745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00030407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00030781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00032474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC92371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="149" mass="16548" checksum="A280C315A416E97E" modified="2018-07-18" version="1">MKIAIQTADFDVSAELAALRAAHRDIGAIVSFVGTVREANAGSAILHMELEHYPGMTEKSLVYIVQKAEKRWEINDVVVIHRIGVLPVCAQIVLVAVASKHRGTAFEACEFIMDYLKTEAPFWKKEVGEHGAQWVDARSTDLSALDKWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXE7</accession>
    <name>A0A2S9GXE7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transposase IS66 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3037</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92378">
        <property type="protein sequence ID" value="PRC92378"/>
        <property type="gene ID" value="S2091_3037"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039552">
        <property type="entry name" value="IS66_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004291">
        <property type="entry name" value="Transposase_IS66_central"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03050">
        <property type="entry name" value="DDE_Tnp_IS66"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13817">
        <property type="entry name" value="DDE_Tnp_IS66_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_Tnp_IS66" evidence="1">
        <location>
            <begin position="1"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="domain" description="DDE_Tnp_IS66_C" evidence="2">
        <location>
            <begin position="159"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="198" mass="22414" checksum="4AFA43371F6D47AC" modified="2018-07-18" version="1">MVDNYGGYKHLFKQGITELACLAHARRKFFDLHMANKHPVAEEALQRIAELYRIESEATGYSAEERQRWRAEHAKPRLNAMHLWLLQTRKTSAEGGALSRAIDYSLKRWPAILRYADSGHLPIDNNLIENAIRPIAIGKKNWLFAGSERAGKRAAAIQTLLATAKANGIEPFVWLKDTLEKLPTCPNSCIDELLPLRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXF8</accession>
    <name>A0A2S9GXF8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">TPR repeat</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3005</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92346">
        <property type="protein sequence ID" value="PRC92346"/>
        <property type="gene ID" value="S2091_3005"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="41"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="75"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="459" mass="51580" checksum="8B75D60347DBD174" modified="2018-07-18" version="1">MTNHSPAEELFFEGNQCMQSGDLHGAEQCFRQAIAMQPGFGEALANLGHLRSKAGDTQAAESFYRQALAARPALEEAYLMLGVLLMNQKRFSESEQLYRYYLQHNPQSPAAWSNLGVLLACLKRETEAEQCYRTALSMDNNFKKASFNLSYILLRQERWEEGWRCLEDRWPYPVLAGHFTCPRWCGEVLQDKSIIIGFEMGHGDMIFYCRYISELKKRGASRISLICHPGLTQLFKTLSGVDEVFSFNDVVPASGWDYWTPPMSLPHYCQTSAGNFPTPIPYLHAEAAKIAYWKNVLPNDGLRVGLVWKGLALFENDADRSIQSLKVLEPLGAVAGVHFISLQKGQGEDEALNPPAGLALQALGAQLNDFADTAAVIRCLDLVISVDTAVAHLAGAMGVPCWLLLPDYRPDWRWLTERTDTPWYPQQMRLFRQSTEGGWASVIDMVSAALEEWQVSKQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXH3</accession>
    <name>A0A2S9GXH3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">GGDEF: diguanylate cyclase (GGDEF) domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_2785</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92410">
        <property type="protein sequence ID" value="PRC92410"/>
        <property type="gene ID" value="S2091_2785"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001440">
        <property type="entry name" value="TPR_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00515">
        <property type="entry name" value="TPR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="415"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="178"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="218"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="5">
        <location>
            <begin position="501"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="434"/>
            <end position="468"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC92410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="680" mass="75938" checksum="368214806A6E6B54" modified="2018-07-18" version="1">MLNFGTTQADETATSAISAEIIRIQDLAETQVAESIQQLNTLQRSLPPDAKLEDQREVLITLIGLYLNDDQTEQARKLNAELSRLGVHYHDNWSNAIALNFQAAILKVEGKLDEAKDVNAQALQLAKSVNQKKLTCRVYSTASVINSELGNFQLALEYRLIAMEALDEGTRHDDLRRINALNNIGNLYTKLKDPQMALAYFDKGVKLAEQWDAQSMLSMLNLNRGNVYSDQGKLADAVKAYAESLKISRNIADRRGEATALNNLSDATYGLGNYSLCLHYAKQTLQLANKLENSVLQADSLVNVGLCHMGLGEVILGSKEANQGIDILRQSKAKPAIEEILGQLATAFEKANMYKEAYKVIVEKLALSTELFNADRDRVVSEMKARYDASQHEKQIEVLEQKNQIQSIEIKNKSLQWIITTVFSIIAAAVALTILILYRKLRETNRNLKEANSNLEQANTKLAHQSNRDPLTGLLNRRAFHDAMQSRTQITDRRVLSSDTPPHSLVVLDIDHFKRINDNYGHAAGDEVLVELSKRLSHVMRDNDMLMRWGGEEFLIFLNHMPTSNLQQVIERILINVGGSPVVFEKNTIPVTISVGYISLHQGEASDVELNWGKSLNLADSMLFMAKTRGRNQAIGIKKVNVPKEEFDALLRSDLENAIQQGKIIIEQIAGPLQKAEAVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXL5</accession>
    <name>A0A2S9GXL5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PRC-barrel domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2823</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92448">
        <property type="protein sequence ID" value="PRC92448"/>
        <property type="gene ID" value="S2091_2823"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027275">
        <property type="entry name" value="PRC-brl_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011033">
        <property type="entry name" value="PRC_barrel-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05239">
        <property type="entry name" value="PRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50346">
        <property type="entry name" value="SSF50346"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PRC" evidence="1">
        <location>
            <begin position="25"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="128" mass="14529" checksum="0531A64A85E61785" modified="2018-07-18" version="1">MTYGEIDALESVKSIGKHGSRHVLMGANKLIGNKVNNVQGEPLADIMDIMLNMENGNISYAILVKKSVILIDEKLFAVPWNWLKLDTVNHQFILNVDKAQFDNTPGFDPKHWPDTAVQSWIDDIQRHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GY21</accession>
    <name>A0A2S9GY21_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">UvrABC system protein C</fullName>
            <shortName evidence="7">Protein UvrC</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Excinuclease ABC subunit C</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">uvrC</name>
        <name evidence="11" type="ORF">S2091_2668</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Interacts with UvrB in an incision complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the UvrC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92613">
        <property type="protein sequence ID" value="PRC92613"/>
        <property type="gene ID" value="S2091_2668"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009380">
        <property type="term" value="C:excinuclease repair complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009381">
        <property type="term" value="F:excinuclease ABC activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009432">
        <property type="term" value="P:SOS response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.340">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00203">
        <property type="entry name" value="UvrC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000305">
        <property type="entry name" value="GIY-YIG_endonuc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035901">
        <property type="entry name" value="GIY-YIG_endonuc_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003583">
        <property type="entry name" value="Hlx-hairpin-Hlx_DNA-bd_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010994">
        <property type="entry name" value="RuvA_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001943">
        <property type="entry name" value="UVR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036876">
        <property type="entry name" value="UVR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004791">
        <property type="entry name" value="UvrC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001162">
        <property type="entry name" value="UvrC_RNase_H_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038476">
        <property type="entry name" value="UvrC_RNase_H_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01541">
        <property type="entry name" value="GIY-YIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08459">
        <property type="entry name" value="UvrC_HhH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00465">
        <property type="entry name" value="GIYc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00278">
        <property type="entry name" value="HhH1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46600">
        <property type="entry name" value="SSF46600"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47781">
        <property type="entry name" value="SSF47781"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82771">
        <property type="entry name" value="SSF82771"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00194">
        <property type="entry name" value="uvrC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50164">
        <property type="entry name" value="GIY_YIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50151">
        <property type="entry name" value="UVR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50165">
        <property type="entry name" value="UVRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="3 7" id="KW-0228">DNA excision</keyword>
    <keyword evidence="5 7" id="KW-0234">DNA repair</keyword>
    <keyword evidence="4 7" id="KW-0267">Excision nuclease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7" id="KW-0742">SOS response</keyword>
    <feature type="domain" description="GIY-YIG" evidence="9">
        <location>
            <begin position="20"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="domain" description="UVR" evidence="8">
        <location>
            <begin position="207"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="domain" description="UVRC" evidence="10">
        <location>
            <begin position="258"/>
            <end position="488"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC92613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="614" mass="68797" checksum="B606049AFC8E0457" modified="2018-07-18" version="1">MSEATPERLLLIETVAKLPHLPGVYRYFDNNDKVLYVGKARDLKKRVSSYFQKNLASPRIALMVDRIARLETTVTRSEAEALILENNLIKALHPRFNILFRDDKSYPYLKISGQAVPRMMYYRGAIDKNNHYFGPFPSAWAVKESIQILQKVFQLRSCEDSVYANRTRPCLLHQIHRCSAPCVGIISEEDYAQDVSNAAQFLRGRQSEVMQVLEKRMLGYAEQLAFEKAAVVRNQMSALSKVLHQQGMESANDVDLDIIAVFIKGGRACVNLAMVRGGRHLGDRAYFPSHVDEAVTEGILEAEVLQAFLAQHYLDQYIPSLLVVSCVLDAPELLIALMEQCGHKIHMVTQPQEQRRQWLEMAQKGAELALARLLTEQGSQQARTRALAEALNLDAADLDALRVECFDISHTQGEATQASCVVFLHHAMQNAEYRRYNINDITPGDDYAAMRQVLQRRYEKVASNNGVMPDIVLIDGGKGQVEIARQVFVELGLDISLIVGVSKGEGRKVGLETLVFVDGRAAQELGRESAALMLIAQIRDEAHRFAITGMRAKRAKARQTSRLEEIEGIGAKRRQKLLVRFGGLKGVADASIEDLASVDGISRQLAEQIYKQLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GY70</accession>
    <name>A0A2S9GY70_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative small protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2716</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92661">
        <property type="protein sequence ID" value="PRC92661"/>
        <property type="gene ID" value="S2091_2716"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019226">
        <property type="entry name" value="DUF2158"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09926">
        <property type="entry name" value="DUF2158"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="59" mass="6361" checksum="BF8DDC0FA9017E90" modified="2018-07-18" version="1">MADALKPGDTVKLKSGSSLMTVSELYPNGKVNCSWFLDGDVKTAVFIKETLKLQTATPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GY80</accession>
    <name>A0A2S9GY80_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2728</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92673">
        <property type="protein sequence ID" value="PRC92673"/>
        <property type="gene ID" value="S2091_2728"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025395">
        <property type="entry name" value="DUF4128"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13554">
        <property type="entry name" value="DUF4128"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="135" mass="14653" checksum="7AEF70160DDFF83F" modified="2018-07-18" version="1">MSDVKIRAALETALVAVMPTFQFAWENVMFVPTAGIPFAKVTLKMAQPQNPTLGAGFHRERGIMFVGLAYPLGQGSLASMTQAELIKTAFARGSSFASNGVTVIVDSTPEIVPAITDADRYNIPVKIRFWADIYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYJ7</accession>
    <name>A0A2S9GYJ7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2524</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92794">
        <property type="protein sequence ID" value="PRC92794"/>
        <property type="gene ID" value="S2091_2524"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="59" mass="6195" checksum="9C2781AD0C142ED2" modified="2018-07-18" version="1">MSDVKKNDVENKDEKDAGLDVTKVTFDKNGEVTGLSDEVLDSVSGGLKSVNNSCTNSGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYP8</accession>
    <name>A0A2S9GYP8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2558</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92828">
        <property type="protein sequence ID" value="PRC92828"/>
        <property type="gene ID" value="S2091_2558"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010281">
        <property type="entry name" value="DUF885"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33361">
        <property type="entry name" value="PTHR33361"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05960">
        <property type="entry name" value="DUF885"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015492442" evidence="1">
        <location>
            <begin position="30"/>
            <end position="605"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="605" mass="68258" checksum="8242B056F2EE0BA0" modified="2018-07-18" version="1">MRYSSVSAHAMRSIVLASMALCSPMLSLAASSANSASVPNTSAGAVQSAKLNHAFDQLSQQFLTSLWRISPEMAIGFGKFDNASQLTIPDQHSRDQWNAFAKQWLAKFSAVDASKLPVQQSSDLALIQNFLNGSVWQLTTFREFEWNPSEYNIAGEIDSILNTDYASKAERIHTLIKRLKNVPAYYAAARASIVRPTMEHTQLAIQQAPGALVMLDQVEQEAKAVKLNKLEQSELKERIAEARTAINGYKEWLVELAKNQNPSNTRSFRIGADLYEAKFGFDIQSSFTAKEMFQRAVAAKQAMHQNMDKLADELWPKYMGEQVKPENSLEKIGMVIDKLSANHTTPDKLMSDVRAHIPALESWITSHDLLDLDPSKPLVIRETPEYQRGVTMASLDSAQPFTPTRDTYYNVTPITDKTPEQTESLLREYNHWVLQILSIHEAVPGHYVQLLHANRSPSIIKSLFGNGAMIEGWAVYGERMMLESGYGDNAPEMWLMYSKWNLRSICNTILDYSVHVLGMSQEDAMHLLTKEAFQSEAEAAGKWRRVQLTSVQLDSYFSGFSEIMALREERKQALGDKFDLKQFHEQFLSYGSAPVRMIRGFMEKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYR7</accession>
    <name>A0A2S9GYR7_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Type II secretion system protein H</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">General secretion pathway protein H</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">S2091_2276</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the GSP H family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92859">
        <property type="protein sequence ID" value="PRC92859"/>
        <property type="gene ID" value="S2091_2276"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015627">
        <property type="term" value="C:type II protein secretion system complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015628">
        <property type="term" value="P:protein secretion by the type II secretion system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022346">
        <property type="entry name" value="T2SS_GspH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002416">
        <property type="entry name" value="T2SS_protein-GspH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12019">
        <property type="entry name" value="GspH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01708">
        <property type="entry name" value="typeII_sec_gspH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0488">Methylation</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="domain" description="GspH" evidence="13">
        <location>
            <begin position="59"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004377"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00025772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00030775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF12019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="PRC92859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="170" mass="18699" checksum="16B07A55108D12DA" modified="2018-07-18" version="1">MLTSAAKPSAAKTSPQAHRKAAGFTLLELLVVLVVVGIMLGMVSMNALPNKKQALLGDAKRVALLLQLAREEAIVRNRPVAFELDSEQFRFYVRGDSGWQLLNDNDLFRERSFKNSPLAITMQPSPNQTALPLKIIFGREPVDKPFTLTFGYEDATATIQADGIGHFSVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZ46</accession>
    <name>A0A2S9GZ46_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Sulfotransferase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2397</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92980">
        <property type="protein sequence ID" value="PRC92980"/>
        <property type="gene ID" value="S2091_2397"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="274" mass="31572" checksum="719C53AE7A737DAA" modified="2018-07-18" version="1">MIPKFVGVTGLPRAGSTLLCQLLAEHPEIQCEGHSSPLCNTLLGIRRMISDDSFFLSQLDNSFDSSYAHLASAMRGFLRGWNQDSQQKVVVDKNRAWLHAIELLLHIEPEAKLIVCLRDLGQILGSIEAQHQRTILVDFIDHLADYDRFGRADMLFAKDKIIGAPLISLHAVTDLPKKVQERLYFLRFEDMVERPVACMSHLYAWLGVSPFDINPDKLNVGIRESDSHYHMKYMHKQVERIIKPVAHELSPRIQAQIENTYAWFYQQYYPQKNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZ62</accession>
    <name>A0A2S9GZ62_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Oligoendopeptidase F</fullName>
            <ecNumber evidence="6">3.4.24.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">S2091_2414</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Has oligopeptidase activity and degrades a variety of small bioactive peptides.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="6">Binds 1 zinc ion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the peptidase M3B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="6"/>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92997">
        <property type="protein sequence ID" value="PRC92997"/>
        <property type="gene ID" value="S2091_2414"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1370.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013647">
        <property type="entry name" value="OligopepF_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042088">
        <property type="entry name" value="OligoPept_F_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045090">
        <property type="entry name" value="Pept_M3A_M3B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001567">
        <property type="entry name" value="Pept_M3A_M3B_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004438">
        <property type="entry name" value="Peptidase_M3B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11804">
        <property type="entry name" value="PTHR11804"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01432">
        <property type="entry name" value="Peptidase_M3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08439">
        <property type="entry name" value="Peptidase_M3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00181">
        <property type="entry name" value="pepF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 6" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1 6" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="4 6" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015635833" description="Oligoendopeptidase F" evidence="7">
        <location>
            <begin position="29"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M3_N" evidence="9">
        <location>
            <begin position="134"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M3" evidence="8">
        <location>
            <begin position="226"/>
            <end position="608"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU368091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC92997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="625" mass="70603" checksum="46324B23BAD691C7" modified="2018-07-18" version="1">MTKNISLATTLAATFTLVSALLPSLSSAAETENDRWNLADLYATQDAWEFDSQQLEKQLKEFSACQGKLGESVKRFKSCLDLNADMVKRFVRLSSYASQSRDQDTGATLGQDLSQRADILAVKLDEATSFIRPEILKLGANKVTHFINQDKTLQQYRHFMDGILRTAPHTLDASGESLVANFGSATNAGQSVYTTLSNADMPWPTVKLSDGTEVKLDQAAYTKYRAADNRADRKIVFDAFWGKWKEFERTYGVTFYEQLKKESVYTKVRHYPDSLTRALDGNNLPPAVYNMLIEQTHANLPTLHRYFKLRAKMLGVTDLHYYDIYPPIVSSNLKYPVEQGKELMLAAVQPLGSDYVAAMQNGLQHRWMDVYPRPHKLSGAYMNGAVYDVHPYLLLNYNDDYESISTLAHEWGHAMHSYLANKAQPYINADYPTFTAEIASTTNEVFMLDHMLKIAKNDDEKLLYLGSALENLRGTFFRQAMFADFERTVHAKVDKGESLTGEDITKIYTDILKRYHGDAEGVMKIDDLYGIEWAYIPHFYNQFYVFQYATSIAAGSMFAGQILSHPNDKAVRENYLNVLRSGGSADPYDVVKAAGVDLASPAPYQAIFARMNSIMDQIEAIQKKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZC6</accession>
    <name>A0A2S9GZC6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phage major capsid protein, HK97 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2167</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93081">
        <property type="protein sequence ID" value="PRC93081"/>
        <property type="gene ID" value="S2091_2167"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024455">
        <property type="entry name" value="Phage_capsid"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05065">
        <property type="entry name" value="Phage_capsid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01554">
        <property type="entry name" value="major_cap_HK97"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="57"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="406" mass="43306" checksum="89ED049B145BFCFA" modified="2018-07-18" version="1">MKQTAIARGIQSVRAETDVSALIGSLNKAFADFKAENDRQLNDIKKGSADALQALKVENINADIANLQRAVDDANSRMAAAELNGGASAGLKDKEYSAAFSAHFKKGDVQAALNKGTASDGGYLAPVEWDRSITDRLIEVSPLRQLCFVQTIGNAGFSKLFAHRGATSGWVGEAEERPETGTPTLSSLAYETGELYANPAATQQMLDDSEINLEVWLAGEVETEFAYQEGIAFLTGSGDKKPRGLLTYITGGVNANKHPYGDIKTIKSNAAATITADSLIDLTESLPTALTAGASMIANKSTITAARKLKDGQGNYLWQPSFTAGKPATINGYGITEVAGMPAIAANSIPIMFGDFKRGYMIIDRMGVRVLRDPFTKKPFVSFYTTKRVGGGLLNPDYLKALKISA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZC9</accession>
    <name>A0A2S9GZC9_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF4124 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_2144</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93058">
        <property type="protein sequence ID" value="PRC93058"/>
        <property type="gene ID" value="S2091_2144"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025392">
        <property type="entry name" value="DUF4124"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13511">
        <property type="entry name" value="DUF4124"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5016376958" description="DUF4124 domain-containing protein" evidence="2">
        <location>
            <begin position="25"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4124" evidence="3">
        <location>
            <begin position="13"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="83"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="127"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="150"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC93058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="166" mass="18317" checksum="8BDB12A496E3AD65" modified="2018-07-18" version="1">MKLSIRHTLIVLATLATISTSALAQYVWLDEKGNKQFSDQPPPASVPKNKILKFSGKIIDNQDSSTDADNSKAGTTKPADSLADKELAFKKRRDELAAKEKKDADEAKASAAKSDNCKRMREYKQSLDSGQRISQMDATGQKSYMTDEKRAQEQTQLSQNLSDCGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZK3</accession>
    <name>A0A2S9GZK3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">O-acetylhomoserine sulfhydrylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_2251</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 3">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the trans-sulfuration enzymes family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93165">
        <property type="protein sequence ID" value="PRC93165"/>
        <property type="gene ID" value="S2091_2251"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019346">
        <property type="term" value="P:transsulfuration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00614">
        <property type="entry name" value="CGS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000277">
        <property type="entry name" value="Cys/Met-Metab_PyrdxlP-dep_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11808">
        <property type="entry name" value="PTHR11808"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01053">
        <property type="entry name" value="Cys_Met_Meta_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001434">
        <property type="entry name" value="CGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="2">
        <location>
            <position position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR001434-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU362118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC93165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="409" mass="43981" checksum="6CA27329FC5E6F07" modified="2018-07-18" version="1">MAGFTTTILHNDRQSLIEHGSVHKPIHTAVTYGYSDARELAEVFQGKKSGYRYGRQGNPTVTALEDKLTKMEDGVASLCFASGMAAIGALPLALLKSGDHVVSSAFLFGNTSNLWQTAANLGVEVSFVDATNVANVEAAITKATRMVFVETIANPRTQVVDLAQIGALCQARGILFVVDNTMTSPYLFRPKAVGAGLVINSLTKAISGHGDVLGGCITDTGAYDWRNYPNIAVNFQKQAVQQWGIAQLRAKSLRDFGACLSPDAAHQIAIGAETMALRIDRQCSNTSQLTEMLAAHPKVAAVYYPGLKNHPQHGLASELFKAQGSIFSFELNADIDCFDFLNHLKIAISATHLGDNRTLIIPVAHTIFFEMGAERRAAMGIAESLIRVSVGIEDPADLLSDFKQALELS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZL2</accession>
    <name>A0A2S9GZL2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2258</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93172">
        <property type="protein sequence ID" value="PRC93172"/>
        <property type="gene ID" value="S2091_2258"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="93" mass="10311" checksum="BB2E8B1BFBDE115F" modified="2018-07-18" version="1">MIYLQISLNIAPINRPAAAAIYSKFKSAFLEQVPGAKSKELLIRDEDVQVQHGFDTRENANAYLHSALFTNDVVVSLKPLLASDPDVRIYAAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZP2</accession>
    <name>A0A2S9GZP2_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Porin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2256</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell outer membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the OprB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93170">
        <property type="protein sequence ID" value="PRC93170"/>
        <property type="gene ID" value="S2091_2256"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046930">
        <property type="term" value="C:pore complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015288">
        <property type="term" value="F:porin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008643">
        <property type="term" value="P:carbohydrate transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006811">
        <property type="term" value="P:ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007049">
        <property type="entry name" value="Carb-sel_porin_OprB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038673">
        <property type="entry name" value="OprB_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04966">
        <property type="entry name" value="OprB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="2" id="KW-0406">Ion transport</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0626">Porin</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015368923" description="Porin" evidence="2">
        <location>
            <begin position="22"/>
            <end position="453"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU363072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC93170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="453" mass="49250" checksum="9493D8FEA0424746" modified="2018-07-18" version="1">MAAMLAVCFSLTVLSSDLAHAVDTTSSNATTVPPATELLIPDSEAWAIHWQATNITQKHSDFIAPYSGTNSLNPHGGMEETTDTTLFLGLRLWSGAEVWLNPEVDQGFGFDNTLGVAGFPSGGAYKIGANTPYLRFPKLFVRQIIALDGTNEAIAAAPNQLAGSQTSNNVTLTVGKFSVVDIFDTNSYAHDPRADFLNWSIFEAGSYDYAADPWGFTFGAAAEWNQDWWTLRAGFFQLSSEPNGKITRINFGENSTNLEVEARHQWLGHPGKIKLLTWINQGRMASYQDAVALGQATNSTPDVALVRRYSSRAGVALNMEQEISSDIGAFARLSANRGDKETYEFSDINQSISAGLSIKGGTWARENDTIGIAVVMNRISGDAQKYFTAGGLGLLIGDGNLNYAPEKIVEMFYSMQFSSTATASVDYQYIANPAYNQDRGPVSVYSLRLHANF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZQ1</accession>
    <name>A0A2S9GZQ1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2264</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93178">
        <property type="protein sequence ID" value="PRC93178"/>
        <property type="gene ID" value="S2091_2264"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="27"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="99" mass="11272" checksum="C84E4300EBB82054" modified="2018-07-18" version="1">MELAHSIDVTEKINAIRRAKALAEIEWPMSILTQVIGLFFMIAIPIICVWASIASKVALPWYSSIFLMLPAIIFIAGMLMITQRRQEALTELVKQERKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZR0</accession>
    <name>A0A2S9GZR0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2192</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93106">
        <property type="protein sequence ID" value="PRC93106"/>
        <property type="gene ID" value="S2091_2192"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="94"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="94"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="154" mass="16991" checksum="442AA19E730B3805" modified="2018-07-18" version="1">MPWWVSALVLIAASLFFEFHGRSFVQRQWNSDKVVQTQLAKIKQEQRDAENSQLKTQQTTISSTIQKVHDDEISRLTTALNDSRRLRIGSQFCGATSGQTDTQSATSGAAADTGGRVLSEEMDRAVKQLIFESEQVAATGRAAQAFIRENGLGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H012</accession>
    <name>A0A2S9H012_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Glutamate--cysteine ligase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2028</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93290">
        <property type="protein sequence ID" value="PRC93290"/>
        <property type="gene ID" value="S2091_2028"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11280">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011718">
        <property type="entry name" value="GshA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042520">
        <property type="entry name" value="GshA_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08886">
        <property type="entry name" value="GshA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02049">
        <property type="entry name" value="gshA_ferroox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0436">Ligase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="432" mass="48357" checksum="3F427B6B9BE40334" modified="2018-07-18" version="1">MVPHLVTALNGPLLELEKKILEATPAIERWFRLEWQEHTPPFYCSVDLRNSGFKLAPVDTNLYPGGFNNLAPEMLPLAVQAAMAAVEKYCPDAKNLLLIPERHTRNTFYLQNVARLMQIFRQTGLNVRLGSLSEDIKEPTNLELPDGSILTMEPLERSANGRRLGLAGFDPCTILLNNDLSAGIPSILENLNEQTLLPPLHAGWAVRRKTNHFAAYDEVVKKFAKIVDVDPWMLNPYFAKASQINFHERIGEDLLAAQVDAVLTKIRKKYKEYGIKEKPFVIVKADAGTYGMGIMTVRDASDVKDLNRKQRNKMAVVKEGLEVSDVIIQEGVHTFEQINEAVAEPVVYMMDRYVVGGFYRVHSDRGVDENLNAPGAHFVPLAFAQQHALPDVHAKPGTASPNRFYMYGVVARLALLAASLELEKTDPNPEVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H035</accession>
    <name>A0A2S9H035_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Threonine dehydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_2082</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93344">
        <property type="protein sequence ID" value="PRC93344"/>
        <property type="gene ID" value="S2091_2082"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:cellular amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="PLP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000634">
        <property type="entry name" value="Ser/Thr_deHydtase_PyrdxlP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="Trypto_synt_PLP_dependent"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="SSF53686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00165">
        <property type="entry name" value="DEHYDRATASE_SER_THR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PALP" evidence="3">
        <location>
            <begin position="8"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC93344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="309" mass="32407" checksum="8B43C8B1A9923882" modified="2018-07-18" version="1">MQTGMQPLHISTPLLAHRPLSSELGKSVWLKMDNNQPSGSFKLRGIGLLCQRAVANGARHLICPSGGNAGFAAAIAGAALAVKTTILVPEATQESVRAAIRAIGVELIVSGAQWDETNQAALQMSQLDGAVYIPPFDHPDIWDGNATLIDEAVQQAEFDVVICSVGGGGLLSGVVQGLQRNGLSTVPVIAVETEGAASFHAAVQAGELVTLPAITSIATTLAARRVAKHAFELTRSHVIHSVTVSDKQAVDACWRFADDMHTLVEPACGAALAVAYQNLPVLHEFHRPLIIVCGGIGVDMAKLAAWRSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H052</accession>
    <name>A0A2S9H052_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Acetyl/propionyl-CoA carboxylase alpha subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">S2091_2068</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>biotin</name>
            <dbReference type="ChEBI" id="CHEBI:57586"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93330">
        <property type="protein sequence ID" value="PRC93330"/>
        <property type="gene ID" value="S2091_2068"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006164">
        <property type="term" value="P:purine nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005481">
        <property type="entry name" value="BC-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001882">
        <property type="entry name" value="Biotin_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011764">
        <property type="entry name" value="Biotin_carboxylation_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005482">
        <property type="entry name" value="Biotin_COase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005479">
        <property type="entry name" value="CbamoylP_synth_lsu-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011054">
        <property type="entry name" value="Rudment_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02785">
        <property type="entry name" value="Biotin_carb_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00289">
        <property type="entry name" value="Biotin_carb_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02786">
        <property type="entry name" value="CPSase_L_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00878">
        <property type="entry name" value="Biotin_carb_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="SSF51230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51246">
        <property type="entry name" value="SSF51246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="SSF52440"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50979">
        <property type="entry name" value="BC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00188">
        <property type="entry name" value="BIOTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00866">
        <property type="entry name" value="CPSASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00867">
        <property type="entry name" value="CPSASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0092">Biotin</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Biotin carboxylation" evidence="10">
        <location>
            <begin position="1"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-grasp" evidence="9">
        <location>
            <begin position="120"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="domain" description="Lipoyl-binding" evidence="8">
        <location>
            <begin position="587"/>
            <end position="663"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PRC93330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="663" mass="71322" checksum="C085DED9A114CCDA" modified="2018-07-18" version="1">MFTKILIANRGEIACRVAATARRLGVKTVAVYSEADALAKHVAACDEAVLIGPAAAKESYLLGDKIIAVALATGAQAIHPGYGFLSENSEFADACAKAGLVFIGPPASAIRAMGSKSAAKTLMEQAKVPLVPGYHGENQDADFLHKEADRIGYPVLLKASAGGGGKGMRVIENSADFKAALASCKREAISSFGDDKVLAEKYLQRPRHIEIQVFADTFGNCVYLFERDCSVQRRHQKVLEEAPAPGMTEQRRAAMGEAAVAAAKAVGYVGAGTVEFIANQDGSFYFMEMNTRLQVEHPVTEMITGTDLVEWQLRVASGEPLPLLQPQLRIHGHSIEARVYAENPEKGFLPSIGTLVHARTPEAVNFELGGSSDPASFRIDSGVREGDTISPFYDPMIAKMIVWGKDRNEALARMAQALAQYQIVGLSSNIGFLQRLIHSKAFSSADLDTGLIERNQAELFPAPAVMTLPVLALAATKLLLSECHANSSDPWASSHGWRMNSSLLRTLRFESEGDVHEVVVRYLADGWSMSGAGSEARVRLAQTEHTLSIQVGELTVSGTVVRHGEHFHVFNQGQHVELTYTDPLLHAGEAEAETGRLTAPMPGKIVALLVAAGQAVKKGEPLLIMEAMKMEHTIAAPVDGVVKELMYLVGDQVADGAQLLMFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H093</accession>
    <name>A0A2S9H093_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">2-keto-3-deoxy-6-phosphogluconate aldolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1791</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the KHG/KDPG aldolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93404">
        <property type="protein sequence ID" value="PRC93404"/>
        <property type="gene ID" value="S2091_1791"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00452">
        <property type="entry name" value="KDPG_aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000887">
        <property type="entry name" value="Aldlse_KDPG_KHG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30246">
        <property type="entry name" value="PTHR30246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01081">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="217" mass="22572" checksum="AE3676B31552C84D" modified="2018-07-18" version="1">MSNYTSRFTAAFSALPLVAILRGIHPSEVEAVAAALYAEGFRLIEVPLNSPQALDSIKLLRRCLPDDALVGAGTVLTTNAVVQVQDAGGTLIVMPHADLVVIAASKQAGMACVPGVTTLTEAFSAYFSGADALKLFPAELIPPVALKAMRAVLPPALPVMPVGGITTSNMAEYRQAGAQGFGLGSALFSSGMVATDVAKRGRLFADKWQQISNTEIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0N2</accession>
    <name>A0A2S9H0N2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1914</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93527">
        <property type="protein sequence ID" value="PRC93527"/>
        <property type="gene ID" value="S2091_1914"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="55" mass="6583" checksum="DFE6D96E93726111" modified="2018-07-18" version="1">MFYSDINNISLMQKNKKNVALAWFYHMYKTKLIRKIMMAAVKQCKLICCKLSTNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0Q0</accession>
    <name>A0A2S9H0Q0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1925</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93538">
        <property type="protein sequence ID" value="PRC93538"/>
        <property type="gene ID" value="S2091_1925"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032874">
        <property type="entry name" value="DDE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13610">
        <property type="entry name" value="DDE_Tnp_IS240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_Tnp_IS240" evidence="1">
        <location>
            <begin position="76"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="170" mass="20332" checksum="621B46B59FFB364B" modified="2018-07-18" version="1">MNSSKPLYFRRRFPSEIISHCVWLYFRFSLSYRDIEEMMGKRGVIVFYETIRDWSQKFGGIYAKRLRARSNRPNDYWHLDEVYLSINGKSHYLWRAVDQDGEILDILVQPRRNKYAVKKFFRKLLKKLHYIPRVIITDKLRSYAAAKAEIMPGVKHVQDKGATNRAENSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0U2</accession>
    <name>A0A2S9H0U2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Metal-dependent hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1574</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93573">
        <property type="protein sequence ID" value="PRC93573"/>
        <property type="gene ID" value="S2091_1574"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="SSF56219"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Endo/exonuclease/phosphatase" evidence="1">
        <location>
            <begin position="6"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="253" mass="28980" checksum="3F1832EAB58D3354" modified="2018-07-18" version="1">MKLHIATYNIHKGVSWFAQKPRIHDMRAALQSLDADLLFLQEVQGQHDRRAQRHEHWPSEGQHDYIAGDRRQAAYGMNATYQHGHHGNALLSRYPILHYKNQDVSDHRFEERGILHCVVQMLEKEVHCYVVHFGLFAAGRRRQTDLLIQSIHSGTPPDAPLIIAGDFNDWRNHLSEPLRQQLGVEEVFEHLSIQRIGRPKQAKAAMTFPVGAPFLPLDRIYVRGIQIKSAKVLQGSPWARLSDHAPLTADLEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0Y2</accession>
    <name>A0A2S9H0Y2_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">S-adenosylmethionine:tRNA ribosyltransferase-isomerase</fullName>
            <ecNumber evidence="5">2.4.99.17</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Queuosine biosynthesis protein QueA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">queA</name>
        <name evidence="6" type="ORF">S2091_1645</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>7-aminomethyl-7-carbaguanosine(34) in tRNA + S-adenosyl-L-methionine = adenine + epoxyqueuosine(34) in tRNA + H(+) + L-methionine</text>
            <dbReference type="Rhea" id="RHEA:32155"/>
            <dbReference type="Rhea" id="RHEA-COMP:10342"/>
            <dbReference type="Rhea" id="RHEA-COMP:10346"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16708"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:82833"/>
            <dbReference type="ChEBI" id="CHEBI:82834"/>
            <dbReference type="EC" id="2.4.99.17"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5">tRNA modification; tRNA-queuosine biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the QueA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.99.17" evidence="5"/>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93644">
        <property type="protein sequence ID" value="PRC93644"/>
        <property type="gene ID" value="S2091_1645"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00392"/>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051075">
        <property type="term" value="F:S-adenosylmethionine:tRNA ribosyltransferase-isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008616">
        <property type="term" value="P:queuosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1780.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00113">
        <property type="entry name" value="QueA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003699">
        <property type="entry name" value="QueA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042118">
        <property type="entry name" value="QueA_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042119">
        <property type="entry name" value="QueA_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036100">
        <property type="entry name" value="QueA_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30307">
        <property type="entry name" value="PTHR30307"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02547">
        <property type="entry name" value="Queuosine_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111337">
        <property type="entry name" value="SSF111337"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00113">
        <property type="entry name" value="queA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4 5" id="KW-0671">Queuosine biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 5 6" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC93644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="351" mass="38902" checksum="F6EA55F481BCECA9" modified="2018-07-18" version="1">MHQPTYSLSDFNFDLPQELIAQTPLSKRSASRLLQVAGSTLIDSNFEDLVQQLSKDDVLVFNDTRVLKARFFGIKNTGGKVEVLVERVLFNNPEQHSVLAQIRASKSPAIGSTIRLADAFEVEVGERAGEFYTLHFPSDVFDLLEAYGKLPLPPYIEHAADDYDETRYQTVYSKVPGAVAAPTAGLHFDEALLEQCRVKGVQFAYVTLHVGAGTFQPVRHEDLSQHDMHSEWYSVPEETLAAVKKAQAAGRDVIAVGTTSLRALESASQSGQLEAGNANTRLFITPGYCFKTVTRLVTNFHLPKSTLLMLVSAFAGYDEIRAAYQHAIAQKYRFFSYGDAMLLTNNVKKES</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0Y3</accession>
    <name>A0A2S9H0Y3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1640</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93639">
        <property type="protein sequence ID" value="PRC93639"/>
        <property type="gene ID" value="S2091_1640"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="280" mass="31491" checksum="42F235CA492ACCBF" modified="2018-07-18" version="1">MNETFQVKINGIKDGVEIDHVIYRLVILFKRSKNEVQRMFETEGFIVKKGVDLPKAIKYKTVLENSGCVCTIELVNKPDPFTIHDISVRTDKFRTKQESQTSSANISGLNITETNDAATHASATITNEIGTTIGGERFLAQTPQKFCCHCGGNSEVSTIETDFFMDLVFSTQFKKEKSISLALPYCPTCALGIDAPKSSSNTPVKIKDFSRNPNPTRYERSALLFVSMITALMRMIFKLLGQQDTDYIKKIAIKFSNPEYAKAFKKNNKHFIDEGFIKIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H181</accession>
    <name>A0A2S9H181_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">Malonyl-[acyl-carrier protein] O-methyltransferase</fullName>
            <shortName evidence="5">Malonyl-ACP O-methyltransferase</shortName>
            <ecNumber evidence="3 5">2.1.1.197</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Biotin synthesis protein BioC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">bioC</name>
        <name evidence="7" type="ORF">S2091_1704</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>malonyl-[ACP] + S-adenosyl-L-methionine = malonyl-[ACP] methyl ester + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:17105"/>
            <dbReference type="Rhea" id="RHEA-COMP:9623"/>
            <dbReference type="Rhea" id="RHEA-COMP:9954"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:78449"/>
            <dbReference type="ChEBI" id="CHEBI:78845"/>
            <dbReference type="EC" id="2.1.1.197"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 5">Cofactor biosynthesis; biotin biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the methyltransferase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.197" evidence="3 5"/>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93703">
        <property type="protein sequence ID" value="PRC93703"/>
        <property type="gene ID" value="S2091_1704"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00078"/>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010340">
        <property type="term" value="F:carboxyl-O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102130">
        <property type="term" value="F:malonyl-CoA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009102">
        <property type="term" value="P:biotin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00835">
        <property type="entry name" value="BioC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011814">
        <property type="entry name" value="BioC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0093">Biotin biosynthesis</keyword>
    <keyword evidence="5 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_11" evidence="6">
        <location>
            <begin position="50"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012327"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC93703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="299" mass="33308" checksum="68CE6AEA8908E2B0" modified="2018-07-18" version="1">MQSAPIDLNRVRQLFSQPAALQAADFINREIAARMLERLQLVRLDPAQVVDAGCGRGAEVGVLQNNYPNAQIIGIDASQELLQLALQEPKATALSMQGLLSKWLFSGKKNSNLINGDFCRTSLADQATDLVWSNLALHWHPEPDQVFKEWRRILRVNGLLMFSCFGPDSLKEIRHAFNDIDQTPHTLPFVDMHDFGDMLVGAGFATPVMDMEVITLTYSTAAQLLAEVRSMGGNPLQTRGKGLIGKMAWQHMCNKLEQLRNEDGLIPLTLEIIYGHAFKPAPKRGNPGESIIKFEHLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1K3</accession>
    <name>A0A2S9H1K3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Pyruvate ferredoxin/flavodoxin oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">S2091_1747</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93746">
        <property type="protein sequence ID" value="PRC93746"/>
        <property type="gene ID" value="S2091_1747"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016903">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07034">
        <property type="entry name" value="TPP_PYR_PFOR_IOR-alpha_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.920.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019752">
        <property type="entry name" value="Pyrv/ketoisovalerate_OxRed_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002880">
        <property type="entry name" value="Pyrv_Fd/Flavodoxin_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002869">
        <property type="entry name" value="Pyrv_flavodox_OxRed_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011766">
        <property type="entry name" value="TPP_enzyme-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01558">
        <property type="entry name" value="POR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02775">
        <property type="entry name" value="TPP_enzyme_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="SSF52922"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53323">
        <property type="entry name" value="SSF53323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="4" id="KW-0249">Electron transport</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="9">
        <location>
            <begin position="663"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC93746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="1189" mass="129137" checksum="435E9F18DD70BC46" modified="2018-07-18" version="1">MNDISKPSPSELALSASPGAPASDAISLEDKYALKRGRAFMTGTQAFIRLAMLQHQSDVKAGLNTAGYITGYRGSPLGGVDTTAEKAKKYLEAEHVKFHPGMNEDLAATTVWGTQQVNLFPGAKYDGVFSIWYGKGPGVDRCGDVFKHANNAGTSKYGGVVVLAGDDHAAKSSTTAHQSEHILNACGIPVLYPSSVQEYLDYGMHGFAMSRYTGLWVAMKCVTDIVESGAVVEIDPDRVQPVIPTDLTLPADGLNIRQNDAVLAQEARMNNFKWYAALAYARANKLNQIIWDSDHAKIGIITAGKSYLDTRQALADLGIDEQVARDIGLRLYKIGMIWPLESEGVRQFATGLEEILVVEEKRQILEYQLKEELYCWVDKVRPRVVGKFDDTGEWSNLQGAGHGDWLLPATYELSPAQIARAIASRISKYFAGHPVAEKVAERIAFLEAKETLLSVAAKPDPTKDRVPHFCSGCPHNTSTKLPDGSRALAGIGCHYMVLWMDRETTNFSHMGAEGVSWVGQAPFTTEQHVFTNLGDGTYFHSGLLAIRAAVAGKVNITYKILYNDAVAMTGGQVFDGPLDPGMISRQIAAEGVSPIIVVTDEPDKYPADYKWAEGVTVRHRSELDAVQRELREVKGVSAMIYDQTCASEKRRRRKRKEFPDPAIRAVINEAVCEGCGDCSVQSNCLSVEPLETELGRKRQINQSSCNKDYSCVNGFCPSFVTVEGGALKKPKKVEVVGTPMQLPTPQLPSTAEPFGIIVTGVGGTGVVTVGQILAVAAHIEGKACSVLDMSGLAQKGGPVLSHVRIADHDADIHSTRVGTGAADLVIGCDVIVTAGRDALSRMGEGRTYAAINTTTSPTAAFVKNPDWQFPGDSAEAAIRHACGTDRVSLIAAGDIATALMGDNIATNMFMLGYAWQKGWVPLTEASLMRAVELNGVSIGFNKSAFEWGRKAAFDLPAVQKIATPATVIEFKRAPTLEATIAKRVKFLTDYQNAAYAQQYADFVAQVKLAEGRVTETGTRLTEAVAKYLFKLMAYKDEYEVARLHTSGDFAKKIADMFEGDYKINYHLAPPLLAKRDSKGHLVKQKFGPWMTSAFGVLAKFKSLRGTALDIFGYTAERKMERALPVEYRATITALLAQLSKDNLSKAIAIASIPEEIRGYGHVKERHLALAQAKQATLLAGFNEVKKQVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1L2</accession>
    <name>A0A2S9H1L2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1456</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93847">
        <property type="protein sequence ID" value="PRC93847"/>
        <property type="gene ID" value="S2091_1456"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017166">
        <property type="entry name" value="UCP037290"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037290">
        <property type="entry name" value="UCP037290"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="246" mass="27003" checksum="D91713D410085301" modified="2018-07-18" version="1">MSTLQQPNSAFSTAQGLDFPGVWRANELAVSRTATYSTGFDEFDNELPSRGWPRSALIELLLQQPGIGEMQLLKPVLTQLSKTQKIVLIQPPHLPQAMACKSWGIHINNLLWIKTSSATDGLWAAEQILKNGCCGAVILWQGNVRTESLRRLHLAAQSTDTWLWLMRPLAVSMDASPASLRITLRPAAGGVSLNIVKRRGPSAKQNLFIPLADMPVARHYSDKENAPVVMHTRPAVAARSDTPILV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1M1</accession>
    <name>A0A2S9H1M1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1481</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93872">
        <property type="protein sequence ID" value="PRC93872"/>
        <property type="gene ID" value="S2091_1481"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.4150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023225">
        <property type="entry name" value="SipA_chaperone-bd"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="299"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="350"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="391"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="438"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="571"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="350"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="605" mass="65412" checksum="B5A6B71CED4F6C98" modified="2018-07-18" version="1">MGTINPLPGTGQANYLSPSPGGASSSYGFGSEVQGVSSSNNVFSPSVELCPREGLYDENQQVIDDLARGVHKDVFEDLLKNWSPDSSSADSNLGGLRTIDIAESKALEAVFKHDSNVESIYKNGSYAAKIGVANIAIALSELSHHDGNADYCVSKQKELCALIVNDKYRLGDESGFSAWKQGNCYEKVEALSKDVFTKLGDPSQGNIFERVMGGEVMPAIRTFIESCFGPQLLKKWAGINEARGLISRPAAASIERALKTIRATVDGASSSSARLHTRANEFRLAHHWSELMRATSLAPDQVKQTSPQSPLGHQPASQPMANNQPPSIIVSPVINNAPIFNNGPIPANNNGGEQVIVESGGSDNGQRLQTSKNPSVISPDAIDGVEGNADTWTHQPQINKGDDTGPYATGDKEEGGRVSVPTSPINTSFTTSIVVPSLSRLDSSDTPQPQRFKKLERPAPSSPVLQRVEQMNSDEGQQVIVESDLSNNGQRFHIHSNSNINDEADHFQQQPPSELSFKQKIELYDKQNIGVQQPSSVHVSSVLTGNNRLSTTSWPILKAVPDPSHKYMDEKGKNWRSDYDGGSSFNGSSWDLRVDGAYQRSVNKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1X4</accession>
    <name>A0A2S9H1X4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Type III secretion apparatus protein SpaR/YscT/HrcT</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">S2091_1475</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 8">Cell membrane</location>
            <topology evidence="2 8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the FliR/MopE/SpaR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93866">
        <property type="protein sequence ID" value="PRC93866"/>
        <property type="gene ID" value="S2091_1475"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006605">
        <property type="term" value="P:protein targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002010">
        <property type="entry name" value="T3SS_IM_R"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006304">
        <property type="entry name" value="T3SS_SpaR/YscT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30065">
        <property type="entry name" value="PTHR30065"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01311">
        <property type="entry name" value="Bac_export_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00953">
        <property type="entry name" value="TYPE3IMRPROT"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01401">
        <property type="entry name" value="fliR_like_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="52"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="76"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="188"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="221"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PRC93866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="263" mass="28560" checksum="FF43309D39B5B2C0" modified="2018-07-18" version="1">MSVTYVPMNTSLFFDVNTWLLGAALGFTRLAPVFFMLPFFNSSVLSGATRNAVIAIVAMGFWPVPLATMATIDTNIYVAAIGQELLIGVILGCLLAWPFWVFHAVGNFIDNQRGATLSSTIDPANGVDTSELSNFFNMFAAAVYLQGGGLMLFVEAVSDSYRLCDPLQGCTFSSAPLLSLLTNMSTRMIVIASPVIAAMLLSEFVLGLLSRFAPQLNAFSISLTVKSLVAMLVLLIYFGPLFPDEIMRQSGMANYLPLWFEGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1Y3</accession>
    <name>A0A2S9H1Y3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Trypsin-like serine proteases typically periplasmic</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1167</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC93994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93994">
        <property type="protein sequence ID" value="PRC93994"/>
        <property type="gene ID" value="S2091_1167"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001940">
        <property type="entry name" value="Peptidase_S1C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13180">
        <property type="entry name" value="PDZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00834">
        <property type="entry name" value="PROTEASES2C"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="SSF50156"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="SSF50494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PDZ" evidence="1">
        <location>
            <begin position="304"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="398" mass="42255" checksum="F1083729A39DC8A1" modified="2018-07-18" version="1">MRRLWLLFAQVATICLALLLIVSTLKPEWVNKFSSFGKSAHLTSSTIPMLEAPINTVAPGSYRDAAKRAMPSVVNIFTTKEVKRAKNPLYNDPLFRRFFGQNPNPPPEKQSSLGSGVIVSANGYVITNNHVVNSADEIDVVLTDGRKAIAKVVGTDPETDLALIKIDLPDLPAITLGHIEKASVGDVVLAIGNPFGVGQTITMGIISALARNHLDINTFENFIQTDAAINPGNSGGALIDTNGNLIGINSAIFSQNGGSLGIGFAIPVSTVKSVMDGIMANGHVIRGWIGVEPQDVTPELAENFGVKENAGTLIAGVIRSGPADRAGVKPGDILVKVNDTQVTDRVAMMNLIAQLPPDQKAKLTFLRKGKTLTLDVLIGTRQPQPVSTTNDDDEDGAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1Z2</accession>
    <name>A0A2S9H1Z2_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Imidazole glycerol phosphate synthase subunit HisH</fullName>
            <ecNumber evidence="9">4.3.2.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">IGP synthase glutaminase subunit</fullName>
            <ecNumber evidence="9">3.5.1.2</ecNumber>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">IGP synthase subunit HisH</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">ImGP synthase subunit HisH</fullName>
            <shortName evidence="9">IGPS subunit HisH</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">hisH</name>
        <name evidence="12" type="ORF">S2091_1177</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>5-[(5-phospho-1-deoxy-D-ribulos-1-ylimino)methylamino]-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + L-glutamine = 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate + H(+) + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:24793"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58278"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:58475"/>
            <dbReference type="ChEBI" id="CHEBI:58525"/>
            <dbReference type="EC" id="4.3.2.10"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 9">
            <text>H2O + L-glutamine = L-glutamate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:15889"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="EC" id="3.5.1.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 9">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 5/9.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 9">Heterodimer of HisH and HisF.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.3.2.10" evidence="9"/>
    <dbReference type="EC" id="3.5.1.2" evidence="9"/>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94004">
        <property type="protein sequence ID" value="PRC94004"/>
        <property type="gene ID" value="S2091_1177"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004359">
        <property type="term" value="F:glutaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000107">
        <property type="term" value="F:imidazoleglycerol-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01748">
        <property type="entry name" value="GATase1_IGP_Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00278">
        <property type="entry name" value="HisH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010139">
        <property type="entry name" value="Imidazole-glycPsynth_HisH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42701">
        <property type="entry name" value="PTHR42701"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000495">
        <property type="entry name" value="Amidotransf_hisH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01855">
        <property type="entry name" value="IMP_synth_hisH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 12" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="7 9" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="6 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 9" id="KW-0456">Lyase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GATase" evidence="11">
        <location>
            <begin position="6"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="9 10">
        <location>
            <position position="82"/>
        </location>
    </feature>
    <feature type="active site" evidence="9 10">
        <location>
            <position position="194"/>
        </location>
    </feature>
    <feature type="active site" evidence="9 10">
        <location>
            <position position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000495-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PRC94004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="214" mass="23345" checksum="DA45D44E45980876" modified="2018-07-18" version="1">MNRIVVVDYGMGNLRSVAQALRAAAPEADVVISGEIAAIKQADRLVLPGQGAMPDCMSCLRDSGLHEVLMDAARNKPLFGVCVGEQMLFDWSAEGATIGLGLLPGKVERFDLAGQLQEDGSRFKVPQMGWNQVRQAGTVPHPLWAGVADQSYFYFVHSYYANPANLEHTVGWTDYGQPFASAVARDNIFATQFHPEKSAAAGLQLYQNFANWKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H200</accession>
    <name>A0A2S9H200_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Surface lipoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_1188</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MlaA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94015">
        <property type="protein sequence ID" value="PRC94015"/>
        <property type="gene ID" value="S2091_1188"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007428">
        <property type="entry name" value="MlaA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30035">
        <property type="entry name" value="PTHR30035"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04333">
        <property type="entry name" value="MlaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01805">
        <property type="entry name" value="VACJLIPOPROT"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015618539" evidence="4">
        <location>
            <begin position="20"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="228"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="228"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC94015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="269" mass="29653" checksum="3B5B2ABDD24D91F8" modified="2018-07-18" version="1">MKLKALVLAVSLFALSGCATVPNEDGTQSSRVDPFESMNRSTSAFNDKFDQNLFQPVARAYVNVVPGFVQTGIGNFFGNINDVWTAANSFLQGNVEDGFSDIMRFSLNSTFGFLGILDIASEARIPKHRKDFGQTLGVWGVPNGPYLVIPFLGPSVMRDAAALPADYYADLWTYTRPVYIRNIGSGVRLVDKRAGYLDASSLLEDAALDKYIFIRDAYLQRIASQIESRKDAKQNREDNAEMQRQSDDDVMKEPAMSGTPSAVKPLPTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H252</accession>
    <name>A0A2S9H252_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 10">Beta sliding clamp</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">S2091_1210</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Forms a ring-shaped head-to-tail homodimer around DNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the beta sliding clamp family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94037">
        <property type="protein sequence ID" value="PRC94037"/>
        <property type="gene ID" value="S2091_1210"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009360">
        <property type="term" value="C:DNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00140">
        <property type="entry name" value="beta_clamp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001001">
        <property type="entry name" value="DNA_polIII_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022635">
        <property type="entry name" value="DNA_polIII_beta_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022637">
        <property type="entry name" value="DNA_polIII_beta_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022634">
        <property type="entry name" value="DNA_polIII_beta_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30478">
        <property type="entry name" value="PTHR30478"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00712">
        <property type="entry name" value="DNA_pol3_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02767">
        <property type="entry name" value="DNA_pol3_beta_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02768">
        <property type="entry name" value="DNA_pol3_beta_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000804">
        <property type="entry name" value="DNA_pol_III_b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00480">
        <property type="entry name" value="POL3Bc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00663">
        <property type="entry name" value="dnan"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 10" id="KW-0235">DNA replication</keyword>
    <keyword evidence="9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8 10" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="6 10" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DNA_pol3_beta" evidence="11">
        <location>
            <begin position="7"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="DNA_pol3_beta_2" evidence="12">
        <location>
            <begin position="131"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="domain" description="DNA_pol3_beta_3" evidence="13">
        <location>
            <begin position="247"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR000804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00712"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="PRC94037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="367" mass="40895" checksum="6AF5FD8457784BFF" modified="2018-07-18" version="1">MQLVKTHRDTLLRPLQIVSGIVERRHTLPILANILIRKNGEKVSFLSTDIEVQITTNAAIGSGDEVTATTVAARKLLDILRALPEGEVSLTLVNKRLTVQSGKSRFNLQTLAAEEFPTVAVAEQFNTTVSLPQKTLKHLFNMVHFSMAQQDIRYYLNGLLLVVDGKSVIAVATDGHRLAYCQVETDQEFTRQEVIIPRKTIIELQRLLEDTDEPVQINIANNQVKLNFADIELVSKLVEGKFPDFNRVVPKGYVHNFSIGREPLLRSLQRAAIMTSDKFKGIRCVITPGSMKISSTNADQEEAVEEIEIDYSGDSVDIGFNVTYLLDVLNNLKCDQINIALGDSTSSALITVPGQDDFKYVVMPMRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H288</accession>
    <name>A0A2S9H288_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Sulfotransferase domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1236</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94063">
        <property type="protein sequence ID" value="PRC94063"/>
        <property type="gene ID" value="S2091_1236"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013105">
        <property type="entry name" value="TPR_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07719">
        <property type="entry name" value="TPR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="51"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="85"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="119"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="153"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="187"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="255"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="289"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="323"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="357"/>
            <end position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="755" mass="86485" checksum="E3C8EECFDB001EEB" modified="2018-07-18" version="1">MHSRQNSPNQHQTEEPSQAEIANLLALFTQQHYAEAKACADKLTHQFPQHGFTWKALGAIHKKLGNPEEAITALTKATLFLPTDADVHYNLGNSFLEQSKLSQAESSYRQALVIQPGYMAAHYNLGKVYQASENFDAAQASYRIALSLQPDFVEALSSLGVVLHSLGKIEEGEIYLRRAAEINPNDPQNHTNLANLLQELGNTEQAESLYRQALKINPYSWQPIYNLANLLINQKHLSEAETMYVQVVQLRPEFAEAWFNLGNCLFAQNRHPEAEISYREALRINPDYAEAHNHLGIALREQERLTEAEQSYRNALRLKPDYVDVHYNLGNALSELDRIPEAEVCYHRALEFNPDYAEAHNNLGIALKTAGRLEEAKLSLEKAMSINPEFLEPYVGIASLKTYRENDPQIALLEKQLATVHELKPEAQIRFWFAIGKMYEDLGRFDASFSAYEKGNRLKFSSVTWDEEKEIAFIDRIKKLFTKVFFDRSDALADMTNRQPTSNIASERTPIFILGMPRSGTSLLEQILSTHPSVFGAGELVIMKEVIVNAALSEDYLHYPDAIANFSLEQWHQLGQSYLDKVWELAPHSSHITDKMPANFLHIGMIHLMFPNAKIIHAMRDPMDSCFSCYSRIFSKNNLAFSYDLNSLGHYYNRYITLMEHWHTVLPAGTILDCRYEDLVENTEAQAKRILHYIGLPWDERCLDFHKNKRRVKTASQAQVQKPIYKSSVARWKHYKKYLGPLEELINRRNRELNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2H6</accession>
    <name>A0A2S9H2H6_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">50S ribosomal protein L11</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rplK</name>
        <name evidence="12" type="ORF">S2091_1333</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7 9">Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.</text>
    </comment>
    <comment type="PTM">
        <text evidence="7 9">One or more lysine residues are methylated.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7 8">Belongs to the universal ribosomal protein uL11 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94160">
        <property type="protein sequence ID" value="PRC94160"/>
        <property type="gene ID" value="S2091_1333"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070180">
        <property type="term" value="F:large ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00349">
        <property type="entry name" value="Ribosomal_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.250">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00736">
        <property type="entry name" value="Ribosomal_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000911">
        <property type="entry name" value="Ribosomal_L11/L12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036796">
        <property type="entry name" value="Ribosomal_L11/L12_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006519">
        <property type="entry name" value="Ribosomal_L11_bac-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020783">
        <property type="entry name" value="Ribosomal_L11_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036769">
        <property type="entry name" value="Ribosomal_L11_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020785">
        <property type="entry name" value="Ribosomal_L11_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020784">
        <property type="entry name" value="Ribosomal_L11_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11661">
        <property type="entry name" value="PTHR11661"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00298">
        <property type="entry name" value="Ribosomal_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03946">
        <property type="entry name" value="Ribosomal_L11_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00649">
        <property type="entry name" value="RL11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46906">
        <property type="entry name" value="SSF46906"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54747">
        <property type="entry name" value="SSF54747"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01632">
        <property type="entry name" value="L11_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00359">
        <property type="entry name" value="RIBOSOMAL_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7 9" id="KW-0488">Methylation</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7 8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 7 8" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4 7 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 7 9" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_L11_N" evidence="11">
        <location>
            <begin position="9"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="domain" description="Ribosomal_L11" evidence="10">
        <location>
            <begin position="72"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010537"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00736"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF03946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PRC94160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="143" mass="14962" checksum="426D0A19C4BCCE57" modified="2018-07-18" version="1">MAKKIIGFIKLQVPAGKANPSPPIGPALGQRGLNIMEFCKAFNAQTQGVEPGMPIPVVITAFADKSFTFVMKTPPATYLIKKAAGITKGSPKPHTDKVGKLTRAQAEEIATLKRADLTAADMDAAVRTIAGSARSMGITVEGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2Q0</accession>
    <name>A0A2S9H2Q0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glyoxalase-like domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0886</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94265">
        <property type="protein sequence ID" value="PRC94265"/>
        <property type="gene ID" value="S2091_0886"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041581">
        <property type="entry name" value="Glyoxalase_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18029">
        <property type="entry name" value="Glyoxalase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="4"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="134"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="255" mass="27275" checksum="75A645F39F7663D3" modified="2018-07-18" version="1">MTSNFIWYELLTTDIDAAAKFYSHVVGWKVVDSGQSEMDYRIWMAKEDGIGGLMSIPAEAASSGMKSCWFGYINVPDTDKAVAEIIAAGGQVQWPATDIPNVGRIARMSDPQGAGFYVMTPLGTGKSVAYAEGVPGHCSWNELRTSDGAAGLKFYSKQFGWTNISNMDMGPMGTYHVFSANTEGDIGGVMTMSPECHSPSWLYYFCVDNIDAAMARVVSAGGVVTNGPHQVPGGGWIIQGVDPQACKFALVGPKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2T8</accession>
    <name>A0A2S9H2T8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative esterase of the alpha/beta hydrolase fold</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0874</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94253">
        <property type="protein sequence ID" value="PRC94253"/>
        <property type="gene ID" value="S2091_0874"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010662">
        <property type="entry name" value="Hydrolase_RBBP9/YdeN"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06821">
        <property type="entry name" value="Ser_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="180" mass="19799" checksum="2A1EEC1897144068" modified="2018-07-18" version="1">MGENVFSPLRTLIVPGLNNSGPGHWQTHWQLRYPHFERVEQVCWDTPELLVWSEQLRQSLLSDNRPTLIAAHSFGCLATVHCANSGAPNLIGALLVAPADPEKFGLEKVLLGARLHCPSIVVGSTDDPWMASDRAIYWASQWGSEFVNAGALGHINAESDLGHWEFGLLQIQRLISAARG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H304</accession>
    <name>A0A2S9H304_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0986</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94365">
        <property type="protein sequence ID" value="PRC94365"/>
        <property type="gene ID" value="S2091_0986"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031552">
        <property type="entry name" value="ParE-like_toxin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15781">
        <property type="entry name" value="ParE-like_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="96" mass="10895" checksum="E5D5736CCACA53B8" modified="2018-07-18" version="1">MLTILAVPSFTRISKKLHKTEKLDLEVAMKAVAADPTVGEEKKGDLSGMFVYKYYSNKQQVLLSYHLQPSKFNPESVTFLSIGSHENFYVNLKLIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H351</accession>
    <name>A0A2S9H351_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1030</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94409">
        <property type="protein sequence ID" value="PRC94409"/>
        <property type="gene ID" value="S2091_1030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018655">
        <property type="entry name" value="DUF2086"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09859">
        <property type="entry name" value="Oxygenase-NA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="247" mass="27938" checksum="D64BADE6155DCDE5" modified="2018-07-18" version="1">MTDWRITEKLAIAELDWPRITSDLDKEGYALLPQLLNSVQVKALTTLVRDVDSRERWQSLANLDLGRGNIARLSTPLPDLLDAWREALYRQLAPIAHRWAEILGADCHYPDTLISYLRANHEAGQTDSLTTASCLREGDFQALHQHAEDKYIFPLQLVILLSDPDTDFTGGEFVMTEQRPRMQSRPMVLPLQQGDAALITVAHRPHLGSKGYYRVNLKHAISRVRGGERIGIELLFHNDAQGNPFIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H367</accession>
    <name>A0A2S9H367_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1039</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94418">
        <property type="protein sequence ID" value="PRC94418"/>
        <property type="gene ID" value="S2091_1039"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="120" mass="13450" checksum="C706F5EC2EDE426A" modified="2018-07-18" version="1">MKIANSVLLKKIRHAIDNGNVRKIVLASDDICSHYRERECHDNVADWIASHPNHHAVLGWLITAQCVFALHSVVDTGTELLDITPRPEGGGRELKSFIVEDFPHDHLPPQLIDSGYVEQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H390</accession>
    <name>A0A2S9H390_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Short chain dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1024</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94403">
        <property type="protein sequence ID" value="PRC94403"/>
        <property type="gene ID" value="S2091_1024"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="147" mass="15337" checksum="E54FAF39CCF734D2" modified="2018-07-18" version="1">MSALSNKVAIITGASSGIGYATAKLFAREGASVVVAARRQLELDALVKEITQAGGHAVALTGDVKDEAFAKALVELAIDRFGGLDVAFNNAGTMGDMGATPDVLLSSWEDTIKTNLTSAFLCAKYQLPAMLKRAGVTPMGFNTWQAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3B9</accession>
    <name>A0A2S9H3B9_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Serine proteases of the peptidase family S9A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_1054</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94433">
        <property type="protein sequence ID" value="PRC94433"/>
        <property type="gene ID" value="S2091_1054"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023302">
        <property type="entry name" value="Pept_S9A_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002470">
        <property type="entry name" value="Peptidase_S9A"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02897">
        <property type="entry name" value="Peptidase_S9_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00862">
        <property type="entry name" value="PROLIGOPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015473940" evidence="1">
        <location>
            <begin position="27"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S9_N" evidence="3">
        <location>
            <begin position="27"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S9" evidence="2">
        <location>
            <begin position="499"/>
            <end position="702"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC94433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="711" mass="79114" checksum="984AD8C37FF8FAB3" modified="2018-07-18" version="1">MKLNPPSIATLSVIVALLSAANLAHSTDQQNTADPYQWLEQVTDSKALDWVKGRNAITRAELEQEPDFLTLRSQIQAALDSKEKIPVIGKMGEYFYNFWQDGDHQRGVWRRTSLEEYRKEHPKWETVLDLDELAKTEKENWVFKGSACREPDYDRCLLQLSRGGADAVVVREFDLTSKQFVKGGFVLPEAKSNIEWRDKNSVFVATDFGAGSKTDSGYARIVKLWQRGTPLSQAQTLLEGKKTDISVSGSSSNHLGVHHEIIQRGVGFFDTEYYLYDDAKLDKLDVPGKAGISFFGSQFMVTLREPWVIKDVTYPAGALLAIDFDAYKKGARNFTTLFAPTERTSLTGATATKNYLLVEALDNVKSSMTEWKFVDGKWASRTVHLPTIGSIGVTALDDEHSDGYFLSYSDYLTPSTYMLAQAGNDEREVLKTAPAFFDASPYQTEQKQATSKDGTKVPYFIIHRKDMKLDGQNPTLLYGYGGFQISLTPSYSAGIGLGWLQKGGAYVVANIRGGGEFGPAWHEAAMKENRQKAYDDFAAVAQDLIATNVTNPKRLGTQGGSNGGLLAGVMLTQHPELFNAVISQVPLLDMQRFNKLLAGASWMGEYGNPDVPAEWAYISKYSPYQNVKTDVAYPNVLFITSTRDDRVHPGHARKMAAKMIEQGHKNVRYYENIEGGHGGAANNAQRADMNALQYTFMWKMLQATDSLHAVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3H4</accession>
    <name>A0A2S9H3H4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Addiction module toxin, RelE/StbE family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0535</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94532">
        <property type="protein sequence ID" value="PRC94532"/>
        <property type="gene ID" value="S2091_0535"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2310.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007712">
        <property type="entry name" value="RelE/ParE_toxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035093">
        <property type="entry name" value="RelE/ParE_toxin_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004386">
        <property type="entry name" value="Toxin_YafQ-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40588">
        <property type="entry name" value="PTHR40588"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15738">
        <property type="entry name" value="YafQ_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006156">
        <property type="entry name" value="YafQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143011">
        <property type="entry name" value="SSF143011"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02385">
        <property type="entry name" value="RelE_StbE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-1277">Toxin-antitoxin system</keyword>
    <feature type="active site" description="Proton donor" evidence="2">
        <location>
            <position position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR006156-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="93" mass="10447" checksum="E08F2701FCBA967B" modified="2018-07-18" version="1">MRTIKDSASFKRAYKRVSATPQHKDVNALLHAVLKLLIVDLPLPTKNRDHALSGKLSSYRECHIKPDLLLVYEKPDATILRLVSIGSHSELFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3W1</accession>
    <name>A0A2S9H3W1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">PrpF: probable AcnD-accessory protein PrpF</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0677</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PrpF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94674">
        <property type="protein sequence ID" value="PRC94674"/>
        <property type="gene ID" value="S2091_0677"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019629">
        <property type="term" value="P:propionate catabolic process, 2-methylcitrate cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012709">
        <property type="entry name" value="PrpF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007400">
        <property type="entry name" value="PrpF_protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43709">
        <property type="entry name" value="PTHR43709"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04303">
        <property type="entry name" value="PrpF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02334">
        <property type="entry name" value="prpF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="403" mass="41839" checksum="BA8F088CC596E9B3" modified="2018-07-18" version="1">MSHLPQIKIPATYIRGGTSKGVFFRLQDLPASAQIPGAARDALLLRVIGSPDPYGKQIDGMGGATSSTSKTVILSKSSQADHDVDYLFGQVAIDKAFVDWSGNCGNLSAAVGSFAISGGLVDANRIPQNGIATVRIWQANIAKTIIAHVPMTNGEVQETGDFELDGVTFPAAEVQLEFMDPAAEEEGGGGAMFPTGNLVDDLEVPGIGTLKATMINAGIPTIFVNAADIGYTGTELQDAINSDAKALAKFETIRAYGAVRMGLIKHIDEAANRQHTPKVAFVAPPAAYVSSSGKPVNVADIDLLVRAMSMGKLHHAMMGTAAVAIGTAAAIPGTLVSLAAGGGEQNNAARTAVRFGHPSGTLRVGAQASQDPISGTWSVTKAIMSRSARVLMEGWVRVPGDTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3Z5</accession>
    <name>A0A2S9H3Z5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Flagellin N-methylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0708</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94705">
        <property type="protein sequence ID" value="PRC94705"/>
        <property type="gene ID" value="S2091_0708"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005358">
        <property type="entry name" value="Puta_zinc/iron-chelating_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03692">
        <property type="entry name" value="CxxCxxCC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0966">Cell projection</keyword>
    <keyword evidence="1" id="KW-0969">Cilium</keyword>
    <keyword evidence="1" id="KW-0282">Flagellum</keyword>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="142" mass="16252" checksum="649AD390C351C2EA" modified="2018-07-18" version="1">MQICAFKLTTRMRLLINFSRGYFKSMLAISQKIKFYRKRIPSFECIPGCHDCCGPVTTSSFEMSFLPVKTDEEHDAALNNLSCPHLASEGCSVYEDRPLICRMFGTTPKLLCPHGKRPEEMIDPLIEAEIHEFFLSTRQVLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H420</accession>
    <name>A0A2S9H420_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glutathione hydrolase proenzyme</fullName>
            <ecNumber evidence="4">2.3.2.2</ecNumber>
            <ecNumber evidence="4">3.4.19.13</ecNumber>
        </recommendedName>
        <component>
            <recommendedName>
                <fullName evidence="4">Glutathione hydrolase large chain</fullName>
            </recommendedName>
        </component>
        <component>
            <recommendedName>
                <fullName evidence="4">Glutathione hydrolase small chain</fullName>
            </recommendedName>
        </component>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_0619</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2 4">
            <text>an S-substituted glutathione + H2O = an S-substituted L-cysteinylglycine + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:59468"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:90779"/>
            <dbReference type="ChEBI" id="CHEBI:143103"/>
            <dbReference type="EC" id="3.4.19.13"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 4">
            <text>an alpha-amino acid + an N-terminal (5-L-glutamyl)-[peptide] = 5-L-glutamyl amino acid + N-terminal L-alpha-aminoacyl-[peptide]</text>
            <dbReference type="Rhea" id="RHEA:23904"/>
            <dbReference type="Rhea" id="RHEA-COMP:9780"/>
            <dbReference type="Rhea" id="RHEA-COMP:9795"/>
            <dbReference type="ChEBI" id="CHEBI:77644"/>
            <dbReference type="ChEBI" id="CHEBI:78597"/>
            <dbReference type="ChEBI" id="CHEBI:78599"/>
            <dbReference type="ChEBI" id="CHEBI:78608"/>
            <dbReference type="EC" id="2.3.2.2"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3 4">
            <text>glutathione + H2O = L-cysteinylglycine + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:28807"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:61694"/>
            <dbReference type="EC" id="3.4.19.13"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Sulfur metabolism; glutathione metabolism.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.</text>
    </comment>
    <comment type="PTM">
        <text evidence="4">Cleaved by autocatalysis into a large and a small subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the gamma-glutamyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.2" evidence="4"/>
    <dbReference type="EC" id="3.4.19.13" evidence="4"/>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94616">
        <property type="protein sequence ID" value="PRC94616"/>
        <property type="gene ID" value="S2091_0619"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00204"/>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036374">
        <property type="term" value="F:glutathione hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102953">
        <property type="term" value="F:hypoglycin A gamma-glutamyl transpeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0103068">
        <property type="term" value="F:leukotriene C4 gamma-glutamyl transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006750">
        <property type="term" value="P:glutathione biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006751">
        <property type="term" value="P:glutathione catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.246.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043138">
        <property type="entry name" value="GGT_lsub_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000101">
        <property type="entry name" value="GGT_peptidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043137">
        <property type="entry name" value="GGT_ssub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00066">
        <property type="entry name" value="g_glut_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4" id="KW-0317">Glutathione biosynthesis</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="4 6" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0865">Zymogen</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015722214" description="Glutathione hydrolase proenzyme" evidence="5">
        <location>
            <begin position="25"/>
            <end position="574"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU368036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC94616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="574" mass="60681" checksum="CDB3FC725BC61212" modified="2018-07-18" version="1">MHPPIVRKLSIFLTLLASSLAVQAASVAPVAAEHGMVVTAQHLATEVGVDVLKKGGNAIDAAVAVGYALAVVYPAAGNLGGGGFMTITMADGRKTFLDFREKAPLAATADMYLDANGNVIPGLSTHGHLAVAVPGTVAGMEMALAKYGSMKRAAVIAPAVRLAKEGFVLQQGDVEMLESATERFKQDAPTAAIFLNKGEPYKAGQKLIQKDLATTLTAISQHGADGFYKGAVGHALVESSASGKGIITQADLDQYTARELAPLECNYRGLQIISAPPPSSGGVVICEMLNILEGYPLKEWGFRSAKAVHVQIEAMRHAYVDRNNYLGDPDFVKNPVAHLLDKAYATQIRDSISMTKAGVSSEIQPGTAPHEGSNTTHYSIVDKDGNAASVTYTLNNWFGATVTADKTGVLLNDEMDDFTSKVGVANMFGLMQGAANAIAPGKRPLSSMSPTIVMRDGKLLMVVGTPGGSRIITTVLHTLINVIDYGMTLQEAVDAPRFHEQWMPDVTYVENFGLSPDTRAILVGMGHHFVESQPANHIAAILVGAPKLNGKPVADNKYYGSNDPRRNTGLAAGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H456</accession>
    <name>A0A2S9H456_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Dihydroneopterin aldolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0760</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94757">
        <property type="protein sequence ID" value="PRC94757"/>
        <property type="gene ID" value="S2091_0760"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004150">
        <property type="term" value="F:dihydroneopterin aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006760">
        <property type="term" value="P:folic acid-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006157">
        <property type="entry name" value="FolB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043133">
        <property type="entry name" value="GTP-CH-I_C/QueF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02152">
        <property type="entry name" value="FolB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00905">
        <property type="entry name" value="FolB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FolB" evidence="1">
        <location>
            <begin position="16"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="131" mass="15086" checksum="EC7C03C89CD126AB" modified="2018-07-18" version="1">MNSDLALPQLQDCRRLFLRDYEIFINIGVHDFEKKGEQRVFINIDLYIPLAASTPQHDLLEEVVDYDFMRSTVANRIAQGHIHLQETLCDELAKSMLTHPKVRAVRISTMKPDVYPDCAGVGVEIFKIKEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4D1</accession>
    <name>A0A2S9H4D1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Hemerythrin HHE cation binding domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0045</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94850">
        <property type="protein sequence ID" value="PRC94850"/>
        <property type="gene ID" value="S2091_0045"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012312">
        <property type="entry name" value="Hemerythrin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01814">
        <property type="entry name" value="Hemerythrin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hemerythrin" evidence="1">
        <location>
            <begin position="14"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="176" mass="19990" checksum="F1DA59C01753F3C2" modified="2018-07-18" version="1">MTPLFDSAPGFDQPLAVLKHCHTRIRKQLSTLSKLPAHLQKNGADIEAQQAAFAVIRYFTQGAPNHHLDEEHDLIPMLTGCAQGDDANLLQQLLPEILKEHQQMDAIWQELLPQLNVIQQGVIAQLNEELIKQWSTLYLAHMDKEEQHIAPMAMRLFSSEQMQQLGNAMQARRLTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4D6</accession>
    <name>A0A2S9H4D6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0022</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94827">
        <property type="protein sequence ID" value="PRC94827"/>
        <property type="gene ID" value="S2091_0022"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12802">
        <property type="entry name" value="MarR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00598">
        <property type="entry name" value="HTHMARR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00347">
        <property type="entry name" value="HTH_MARR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50995">
        <property type="entry name" value="HTH_MARR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="1">
        <location>
            <begin position="10"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="151" mass="16245" checksum="C6C250C97B24C72D" modified="2018-07-18" version="1">MNANTEPSASLDFCLQLTRATATIICRIDNAPGNLHGLSFSDFMLLLTLSRAVGEHMRRDDLAESLGLSASGITRTLIPMEKIGLVTRHVIAQDSRAGYAVLSKTGKELLAHALVSTEAISQEVIQTTNQEQLDALSAALDQLARLNLSNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4D8</accession>
    <name>A0A2S9H4D8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">MatE: MATE efflux family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0023</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94828">
        <property type="protein sequence ID" value="PRC94828"/>
        <property type="gene ID" value="S2091_0023"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042910">
        <property type="term" value="F:xenobiotic transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002528">
        <property type="entry name" value="MATE_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01554">
        <property type="entry name" value="MatE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006603">
        <property type="entry name" value="DinF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00797">
        <property type="entry name" value="matE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="46"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="95"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="136"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="163"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="191"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="239"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="281"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="320"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="358"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="386"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="417"/>
            <end position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="469" mass="50682" checksum="CA9DCB9B32020C7A" modified="2018-07-18" version="1">MIKDLTQGSIRRHLITMSIPIGIGMFVQTLYFMVDLYFVGRLGDAALAGVSAAGTIMYIVMALTQMLGVGTVALMARAIGAHDKVDSNLIFNQSLLMSGLCAVVILFTGLALTPYYFHALGADPQTTEMGVNYLRWYAPGLALQFILNALGSALRAGGIVKPVMLVQIISVLINIVLAPILIAGWGTGYPLGVLGAGLASSIAIAVGVIMGAVYFAKQEHFVRFQRNQMHPQWGVWRRILNIGFPAGAEFACFFVFMAVIYSIISHFGPAAMAGFGVGSRLMQAIFLPGMAIAFAVPAIAGQNMGAKAMDRVRETMRQAMYLEVGVMVLLTLVCKFQPSWLVGTFARDPQSALVAAEFLHIISWNFVATGLIFVCSGFFQALGNTWPSLLSTGTRLFLFAIPAYWLSQQPDFTLHQLWYLSVATVACQAMMNLGMLRWQWKKSVAGMASGSATGVAENRNAGELNLSTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4M6</accession>
    <name>A0A2S9H4M6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0127</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94932">
        <property type="protein sequence ID" value="PRC94932"/>
        <property type="gene ID" value="S2091_0127"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="30" mass="3373" checksum="F890428C55110FF7" modified="2018-07-18" version="1">MESLLKAYIHKAIEVERAGLKGSFKNRLAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H576</accession>
    <name>A0A2S9H576_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Acetyl-CoA hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0312</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the acetyl-CoA hydrolase/transferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95117">
        <property type="protein sequence ID" value="PRC95117"/>
        <property type="gene ID" value="S2091_0312"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008775">
        <property type="term" value="F:acetate CoA-transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003986">
        <property type="term" value="F:acetyl-CoA hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006083">
        <property type="term" value="P:acetate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019679">
        <property type="term" value="P:propionate metabolic process, methylcitrate cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1080.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026888">
        <property type="entry name" value="AcetylCoA_hyd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038460">
        <property type="entry name" value="AcetylCoA_hyd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003702">
        <property type="entry name" value="ActCoA_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13336">
        <property type="entry name" value="AcetylCoA_hyd_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02550">
        <property type="entry name" value="AcetylCoA_hydro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AcetylCoA_hyd_C" evidence="2">
        <location>
            <begin position="275"/>
            <end position="426"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC95117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="431" mass="46408" checksum="1EB434C1EA115355" modified="2018-07-18" version="1">MQTPSVSTIYQSKLVNASDALTHVRDGDSIIVPTGVGEPPTLLTALSEQRLRFHDVKVVQILAVRKYGYLDPETTKHVRHVALFYGPASRAGGQAGWIDFIPNYFGEIPGLITSGQTPADVVFSMASPMDEHGFFALSLGTDYTMAAVAKARAVVLEVNPNVPFTHGQCHVHISQVSALVESHEPIVEVGLPVIGSVQAAIGKYVADMINDGATLQIGYGAIPDAVVIQLAEKKDLGIHTEMIGDGILSLIESGAVTNRKKNFHNGKMLATFALGSQKLYRFMHQNPMLEMHPVSYTNDPNIAGLNDNLMTINASLQIDLLGQCGSESLGNVPYSGTGGQSDFVRAANRSRGGKSFIVLPSTAKNDTISRIVPTLANGTHISTSKNDVNYVVTEFGVAQLRGKSAKQRAQELIAIAHPNFREELRAAVNRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H582</accession>
    <name>A0A2S9H582_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0278</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95083">
        <property type="protein sequence ID" value="PRC95083"/>
        <property type="gene ID" value="S2091_0278"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC95083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="117" mass="13589" checksum="D863CFCE13F07DDA" modified="2018-07-18" version="1">MSRVEWMTFSPARISAAEINNGTSQLYKLTVHCNDNESHRIERQIRSESQQNKLVLVRANTRQLEHSNLVCVTVFIKCAAELRAALVKLVQHLGFEPVVRSIRWEKIERLQQMMLTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5B1</accession>
    <name>A0A2S9H5B1_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Riboflavin biosynthesis protein RibD</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="10">Diaminohydroxyphosphoribosylaminopyrimidine deaminase</fullName>
                <shortName evidence="10">DRAP deaminase</shortName>
                <ecNumber evidence="10">3.5.4.26</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="10">Riboflavin-specific deaminase</fullName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="10">5-amino-6-(5-phosphoribosylamino)uracil reductase</fullName>
                <ecNumber evidence="10">1.1.1.193</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="10">HTP reductase</fullName>
            </alternativeName>
        </domain>
    </protein>
    <gene>
        <name evidence="15" type="ORF">S2091_0251</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 10">Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)-pyrimidine + H(+) + H2O = 5-amino-6-(5-phospho-D-ribosylamino)uracil + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:21868"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:58453"/>
            <dbReference type="ChEBI" id="CHEBI:58614"/>
            <dbReference type="EC" id="3.5.4.26"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>5-amino-6-(5-phospho-D-ribitylamino)uracil + NADP(+) = 5-amino-6-(5-phospho-D-ribosylamino)uracil + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:17845"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:58421"/>
            <dbReference type="ChEBI" id="CHEBI:58453"/>
            <dbReference type="EC" id="1.1.1.193"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10 13">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="10 13">Binds 1 zinc ion.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 10">Cofactor biosynthesis; riboflavin biosynthesis; 5-amino-6-(D-ribitylamino)uracil from GTP: step 2/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 10">Cofactor biosynthesis; riboflavin biosynthesis; 5-amino-6-(D-ribitylamino)uracil from GTP: step 3/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 10">In the C-terminal section; belongs to the HTP reductase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.26" evidence="10"/>
    <dbReference type="EC" id="1.1.1.193" evidence="10"/>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95056">
        <property type="protein sequence ID" value="PRC95056"/>
        <property type="gene ID" value="S2091_0251"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00275">
        <property type="reaction ID" value="UER00401"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008703">
        <property type="term" value="F:5-amino-6-(5-phosphoribosylamino)uracil reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008835">
        <property type="term" value="F:diaminohydroxyphosphoribosylaminopyrimidine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.430.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016192">
        <property type="entry name" value="APOBEC/CMP_deaminase_Zn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002125">
        <property type="entry name" value="CMP_dCMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024072">
        <property type="entry name" value="DHFR-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004794">
        <property type="entry name" value="Eubact_RibD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011549">
        <property type="entry name" value="RibD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002734">
        <property type="entry name" value="RibDG_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00383">
        <property type="entry name" value="dCMP_cyt_deam_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01872">
        <property type="entry name" value="RibD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006769">
        <property type="entry name" value="RibD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53597">
        <property type="entry name" value="SSF53597"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="SSF53927"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00326">
        <property type="entry name" value="eubact_ribD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00227">
        <property type="entry name" value="ribD_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00903">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51747">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 10 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="10 12" id="KW-0521">NADP</keyword>
    <keyword evidence="10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-0686">Riboflavin biosynthesis</keyword>
    <keyword evidence="8 10 13" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CMP/dCMP-type deaminase" evidence="14">
        <location>
            <begin position="1"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="11">
        <location>
            <position position="46"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="44"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="72"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="81"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="151"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="165"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="167"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="181"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="193"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="197"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="201"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="204"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="219"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="290"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="292"/>
            <end position="298"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00007417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR006769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR006769-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR006769-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR006769-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="PRC95056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="359" mass="38949" checksum="5AF4B1E5ECFF38E6" modified="2018-07-18" version="1">MQIALEWAEKGLNTTTPNPRVGCVIVKNQQIIGAGFTQPAGQAHAEVQALRNATANGYDVRSATAYVTLEPCSHFGRTPPCADALVNAGLKRVVAAILDPNPQVAGRGLERIRAAGIDVECPVLEDAAHEMNIGFFKRMQTGKPWVRMKAAASLDGKTALHNNQSQWITGAEARADGHHWRARACAILTGIGTLLEDNPQLTVRAFPVTRQPLRIIVDSKLQTPTSAKALNYADSSGALIVYAVPNPEQQARLIAAGAELLYLPNAHGKVDLPALMLELGRREINELHIEAGSKLNGSLIREGCVDELLLYLAPSLLGDARGLFDLPALDDLTQQTRLRFRQIQQIGEDLRVLARFYPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5F6</accession>
    <name>A0A2S9H5F6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Bcct: transporter, betaine/carnitine/choline transporter (BCCT) family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_0415</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95220">
        <property type="protein sequence ID" value="PRC95220"/>
        <property type="gene ID" value="S2091_0415"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071705">
        <property type="term" value="P:nitrogen compound transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018093">
        <property type="entry name" value="BCCT_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000060">
        <property type="entry name" value="BCCT_transptr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30047">
        <property type="entry name" value="PTHR30047"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02028">
        <property type="entry name" value="BCCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00842">
        <property type="entry name" value="bcct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01303">
        <property type="entry name" value="BCCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="53"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="94"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="145"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="192"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="233"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="265"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="323"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="353"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="398"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="451"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="476"/>
            <end position="499"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC95220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="669" mass="73371" checksum="478F0339B6C436C1" modified="2018-07-18" version="1">MPVNSPSKRTTFSWPVVIPSLVFVSLLVVISIINPSAAEHWFASAQSWVTFNFSWFYTLLVAFFLMLLIGIAMSKYGAIRLGPDDAEPEFPFTSWMAMLFAAGMGVGLMYFGVGEPLQHYLTPPLAAGGTPAGAREAMSMTFFHWGFHAWAIYGVVGLVLAYFGFRYNLPLTIRSGLYPILKERINGPWGHAVDVFALCSTIFGIATTVGYGVKQLSAGLGNMTGWHTGDLSFQLGLIVVVVVLAGISAASGLGKGLRILSEINLLIAIVLMGFVLAVGPTLYLLGSFSENLGDYLSSIVEMTFRNYTYEPTKSAGWFGNWTILYWAWWISWSPFVGMFIARISRGRTIREFIVGVLLVPSLFNFMWMTVFGNSAIWIDTHVAAGALGATASNVDALLFQFFSYLPFSALSSIVAVLLIAVFFVTSADSGAFVIDNIASRGNTNSPIWQRLFWAALIGLVACCLLSAGGLKALQAMTLIAALPFGFVMLLLCVGLLRGLQADALHSQQKLSYASNFWTGKHWKRRLAQILHQAGQVETQTFMNEMVQPAMRTMQQEFAKGAVQAEVMVNGDGSVQLKIAQTSLRDFVYGVRCVAKEIPAFALNNDALPASSNAQTYEPTTYFADGRKGYDIQYFSEEELLADILKQYERHLSLSMNAQAQLLQQAPSHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5G3</accession>
    <name>A0A2S9H5G3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0424</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95229">
        <property type="protein sequence ID" value="PRC95229"/>
        <property type="gene ID" value="S2091_0424"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007801">
        <property type="entry name" value="UPF0276"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036237">
        <property type="entry name" value="Xyl_isomerase-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42194">
        <property type="entry name" value="PTHR42194"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05114">
        <property type="entry name" value="DUF692"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51658">
        <property type="entry name" value="SSF51658"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC95229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="294" mass="33014" checksum="89C0ACC48B3EB3B7" modified="2018-07-18" version="1">MSLSDAKIAEFPSFPELGYGVGLRTQHYRDFLRQRPNIDWLEVHSENYFGVGVDLDVLETLRRDYPISLHGVGLGIGSAQGYSSEHVRKIKSLAQRIQPALISEHLCWASVAGRHLNDLLPLPLIHSALDLICERVEHLQDTLQQRILLENVSTYVRFACDEMSETEFLSRLVQRTGCGILLDINNLYVNQVNHGESAQQALTLLQQLPANSIGEIHLAGHLVTDSGLVDHHGCQVDPAVWALYENARQLFGAQIPTLIEWDTDIPELDVLLGEAEQAKQRTERVEEERCALLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5Q6</accession>
    <name>A0A2S9H5Q6_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 6">Phosphate-binding protein PstS</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">S2091_0458</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 6">Part of the ABC transporter complex PstSACB involved in phosphate import.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 6">The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the PstS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95263">
        <property type="protein sequence ID" value="PRC95263"/>
        <property type="gene ID" value="S2091_0458"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042301">
        <property type="term" value="F:phosphate ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035435">
        <property type="term" value="P:phosphate ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005673">
        <property type="entry name" value="ABC_phos-bd_PstS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024370">
        <property type="entry name" value="PBP_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12849">
        <property type="entry name" value="PBP_like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002756">
        <property type="entry name" value="PstS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00975">
        <property type="entry name" value="3a0107s03"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0592">Phosphate transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015537471" description="Phosphate-binding protein PstS" evidence="8">
        <location>
            <begin position="23"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="domain" description="PBP_domain" evidence="9">
        <location>
            <begin position="23"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="region of interest" description="Phosphate binding" evidence="7">
        <location>
            <begin position="30"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Phosphate binding" evidence="7">
        <location>
            <begin position="160"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="59"/>
        </location>
        <ligand>
            <name>phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="77"/>
        </location>
        <ligand>
            <name>phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR002756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR002756-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF12849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC95263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="348" mass="38005" checksum="FFC11F05B701AF85" modified="2018-07-18" version="1">MFSFKKIILGILAISIFQATFADPINGAGSSAAQPLYTKWATAYAQKTGFDVEYDAIGSTAGIKKIKGKLIDFGASDVALSADDLQQNQMIQFPSAISGVVPVVNLPGIKPGELKLNGSILSGIFSHQITKWNDAAITALNPNLSLPKVEIIALARLDGSGTTYNFSDYLSHVSPDWKAHFGCNFIIKWPAEIQQIKGSNGIVATIKQTPNSISYVEYSYVVQEKLSFVQLQNADGNFVSPKPANFEAALNHSGWKTQANFNETLTDKAGPTSWPITMGTFIIMPKVTKNNNQTIAALKFFSWGFIQGDRYVNNLDFVHLPDSIQAKIFKQMMSITDTSGNHLNWSPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSG8</accession>
    <name>A0A2S9GSG8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">AhpC/TSA family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_4614</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000039">
        <property type="protein sequence ID" value="PRC90664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90664">
        <property type="protein sequence ID" value="PRC90664"/>
        <property type="gene ID" value="S2091_4614"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016209">
        <property type="term" value="F:antioxidant activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015036">
        <property type="term" value="F:disulfide oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000866">
        <property type="entry name" value="AhpC/TSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
        <property type="entry name" value="AhpC-TSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Thioredoxin" evidence="4">
        <location>
            <begin position="39"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC90664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="186" mass="20206" checksum="FB793EBECEEC3A9C" modified="2018-07-18" version="1">MTHNSEPSAQRRALLLGALGLGITAAGSLLPSLAQANNLVLGQAAPPLILHTLDGHSIATNDLIGHLLIVTFWASYCEPCREELPLLSAYAEQHAKQGLRVLGFSLDDPGNLNEVKEIAKTLSFPVGLLGSPYAGGYGRIWRMPVSFVIDRAGRLVDNGWDDEQPVWTKERLRRVVDPLLAVTHKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSS5</accession>
    <name>A0A2S9GSS5_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">2-amino-3-ketobutyrate coenzyme A ligase</fullName>
            <shortName evidence="1">AKB ligase</shortName>
            <ecNumber evidence="1">2.3.1.29</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Glycine acetyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">kbl</name>
        <name evidence="3" type="ORF">S2091_4511</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>acetyl-CoA + glycine = (2S)-2-amino-3-oxobutanoate + CoA</text>
            <dbReference type="Rhea" id="RHEA:20736"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:78948"/>
            <dbReference type="EC" id="2.3.1.29"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
        <text evidence="1">Binds 1 pyridoxal phosphate per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid degradation; L-threonine degradation via oxydo-reductase pathway; glycine from L-threonine: step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.29" evidence="1"/>
    <dbReference type="EMBL" id="PUGF01000036">
        <property type="protein sequence ID" value="PRC90763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90763">
        <property type="protein sequence ID" value="PRC90763"/>
        <property type="gene ID" value="S2091_4511"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00046">
        <property type="reaction ID" value="UER00506"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008890">
        <property type="term" value="F:glycine C-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019518">
        <property type="term" value="P:L-threonine catabolic process to glycine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00985">
        <property type="entry name" value="2am3keto_CoA_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011282">
        <property type="entry name" value="2am3keto_CoA_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01822">
        <property type="entry name" value="2am3keto_CoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="1" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="2">
        <location>
            <begin position="50"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="region of interest" description="Pyridoxal phosphate binding" evidence="1">
        <location>
            <begin position="248"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Pyridoxal phosphate binding; shared with dimeric partner" evidence="1">
        <location>
            <begin position="281"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="143"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="192"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="375"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="1">
        <location>
            <position position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC90763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="405" mass="44073" checksum="E19C62C08BCB29A2" modified="2018-07-18" version="1">MSAQTTKHQAAFYTSLENTIDDLREAGLYKVERVLASRQGAEVVSEDGRHLINMCANNYLGLSGNESMVQASIKATEEFGYGLSSVRFICGTQTVHKQLEAALSKFLGTEDTILYAAAFDANGGVFEPLFDIEDAIISDSLNHASIIDGIRLCKAARYRYAHNDMADLEVQLKAAGAAGKRHKIIVTDGVFSMDGTIAQLDKICDLADRYDALVMIDECHASGFMGATGRGTHEHHHVMDRIDIITGTLGKALGGAMGGFVSARFEVVEMLRQKSRPYLFSNTLAPSIAGASLEVLKMLSTNTELRDRLHANTAHFRSEIEQLGFTIKPGTHPVVPVMLFEATVAQKFAARLYELGVLVSGFFFPVVPMGQARVRVQLSAAHTTEQINTVLAAFAQAGRELNIIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GSX5</accession>
    <name>A0A2S9GSX5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4487</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000035">
        <property type="protein sequence ID" value="PRC90824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90824">
        <property type="protein sequence ID" value="PRC90824"/>
        <property type="gene ID" value="S2091_4487"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC90824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="74" mass="8655" checksum="02727A9CCACA373C" modified="2018-07-18" version="1">MKNNAIFSSHRMKRRGYQKGRFPKFCNYIKVSTGIYEARLDPALFFHPVALPKALRMISRIGSYAFQLESKELE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GT19</accession>
    <name>A0A2S9GT19_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4453</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000034">
        <property type="protein sequence ID" value="PRC90872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90872">
        <property type="protein sequence ID" value="PRC90872"/>
        <property type="gene ID" value="S2091_4453"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="111"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="140" mass="15530" checksum="676EFAFDA94D24AE" modified="2018-07-18" version="1">MGIVVKVLLSLLVVVLLGTTIILQRTSLIAEKQKNTTLTNEKAERDQTIKQLQAAEVSNKKRLAQLQTERNRISATLSERETFIENLHHDNPLIQSWADTPLPAAIVQLRQRPAATGASEYHSELSQPPPLHPASSQPNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTE2</accession>
    <name>A0A2S9GTE2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phage-related baseplate assembly protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4271</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000031">
        <property type="protein sequence ID" value="PRC90975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90975">
        <property type="protein sequence ID" value="PRC90975"/>
        <property type="gene ID" value="S2091_4271"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014507">
        <property type="entry name" value="Baseplate_assembly_J_pred"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006949">
        <property type="entry name" value="Baseplate_J-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04865">
        <property type="entry name" value="Baseplate_J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF020481">
        <property type="entry name" value="BAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Baseplate_J" evidence="1">
        <location>
            <begin position="116"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC90975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="300" mass="32842" checksum="CC0FDC83FFF3F781" modified="2018-07-18" version="1">MTNSTIDLSKLPAPAFVEALSFEAILDDMLTDLLERHASYSNLLESDPAYKILEVAAYRELLLRHRINEEGRALLVAFSTGTDLDHIGITYYAGEKRLVICEADPTTSPPTEQLMEEDESYRRRLLLKDDSYSTAGAGNAYKFHALSADGQIKDASVTSPRPGTTVVTILSRTGDGTASEELLDKVRATLNSDEIRPLSEELIVAGAEIVRWELDADIYTYNGPDQNLVLKAAQVSFATYLLEQQLLEADITDSALSRALHVPGVFKVVRRSPLVDIVCTATQAAWCVSTAIHIAGVKPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTF5</accession>
    <name>A0A2S9GTF5_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4289</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000031">
        <property type="protein sequence ID" value="PRC90993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90993">
        <property type="protein sequence ID" value="PRC90993"/>
        <property type="gene ID" value="S2091_4289"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC90993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="98" mass="11028" checksum="D0BBBC4D5BB83372" modified="2018-07-18" version="1">METTLHPGHKAPDFDTKITDFINTYDHYPWPSPPRYIGIAMIVDGSYVAYRTVEAMGMPEALDMLGFLHSIGMRDMIDSIPKKGKFDGIFGFPMDLAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTF8</accession>
    <name>A0A2S9GTF8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_4291</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000031">
        <property type="protein sequence ID" value="PRC90995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC90995">
        <property type="protein sequence ID" value="PRC90995"/>
        <property type="gene ID" value="S2091_4291"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC90995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="117" mass="12982" checksum="F4E2EAC470EAC4B2" modified="2018-07-18" version="1">MSVSLINDHLSFRPATDIFKVWDQGRPTPPNSPLALRALAEAKAAIQHRQVENKSPLTAQLWGVTPAGVRRNILRAAGLEDHRWDCPVHSFSDAERIAMKAAAEHGVRLYERASHAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GTT0</accession>
    <name>A0A2S9GTT0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Dihydroorotase, multifunctional complex type</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_4205</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000029">
        <property type="protein sequence ID" value="PRC91109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91109">
        <property type="protein sequence ID" value="PRC91109"/>
        <property type="gene ID" value="S2091_4205"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004151">
        <property type="term" value="F:dihydroorotase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006221">
        <property type="term" value="P:pyrimidine nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01317">
        <property type="entry name" value="DHOase_IIa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004722">
        <property type="entry name" value="DHOase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="SSF51338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydro-rel" evidence="1">
        <location>
            <begin position="53"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="425" mass="45397" checksum="FB9144C6C7AB2B0C" modified="2018-07-18" version="1">MKLHIKNGHLIDPMNDIDAQLDLFIVFGKIAGIGTAPDNFVADEVIDATGLIVAPGLVDLCARLREPGYEYKATLESELRAAVHGGVTSLVCPPDTDPVLDESGLVGMLKQRARAQRLAHVYPLGALTLGLQGKELTEMAALTEAGCVGFSQAEQIILDTNVLLRAMQYAKTFGYTVWLRPQDAHIGVGGVAHSGAFASRMGLSGVPVMAETIALHTIFELQRATGARVHLCRLSSAAGVELVRQAKREGLDVSCDVGAHHLHLSDADIGFFDANARLSPPLRSTRDRDALRMAVFDGTVDAICSDHTPVDDDEKLMPFAEASPGATGLELLLSLAMKWANESHVNLSVAIAKITSEPARVAGLNAGKLSLGSNADICIFNPAGEWLVEEKALASQGKHTPFLSYTLPAVVHHTIVMGHVVYRLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVG2</accession>
    <name>A0A2S9GVG2_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Acetolactate synthase small subunit</fullName>
            <shortName evidence="8">AHAS</shortName>
            <shortName evidence="8">ALS</shortName>
            <ecNumber evidence="8">2.2.1.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Acetohydroxy-acid synthase small subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">S2091_3647</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>H(+) + 2 pyruvate = (2S)-2-acetolactate + CO2</text>
            <dbReference type="Rhea" id="RHEA:25249"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:58476"/>
            <dbReference type="EC" id="2.2.1.6"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Amino-acid biosynthesis; L-isoleucine biosynthesis; L-isoleucine from 2-oxobutanoate: step 1/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 8">Amino-acid biosynthesis; L-valine biosynthesis; L-valine from pyruvate: step 1/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5 8">Dimer of large and small chains.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 8">Belongs to the acetolactate synthase small subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.2.1.6" evidence="8"/>
    <dbReference type="EMBL" id="PUGF01000020">
        <property type="protein sequence ID" value="PRC91709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91709">
        <property type="protein sequence ID" value="PRC91709"/>
        <property type="gene ID" value="S2091_3647"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00047">
        <property type="reaction ID" value="UER00055"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00049">
        <property type="reaction ID" value="UER00059"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003984">
        <property type="term" value="F:acetolactate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990610">
        <property type="term" value="F:acetolactate synthase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009099">
        <property type="term" value="P:valine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04878">
        <property type="entry name" value="ACT_AHAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004789">
        <property type="entry name" value="Acetalactate_synth_ssu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027271">
        <property type="entry name" value="Acetolactate_synth/TF_NikR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019455">
        <property type="entry name" value="Acetolactate_synth_ssu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039557">
        <property type="entry name" value="AHAS_ACT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30239">
        <property type="entry name" value="PTHR30239"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10369">
        <property type="entry name" value="ALS_ss_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00119">
        <property type="entry name" value="acolac_sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7 8" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ACT" evidence="9">
        <location>
            <begin position="4"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006341"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU368092"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC91709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="163" mass="18087" checksum="E534E43A244B6582" modified="2018-07-18" version="1">MRHIISVLLENEAGALSRVVGLFSARGYNIETLTVAPTEDATLSRLTIVTTGSDDVIEQITKHLNRLIEVIKVVDLTEGAHIERELMLIKVRAVGKEREEMKRTADIFRGRIIDVTEKTYTIELTGNKGKLDAFIDSIERTSILETVRTGGSGIGRGERILKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVK6</accession>
    <name>A0A2S9GVK6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative translation initiation inhibitor yjgF family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_3508</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000019">
        <property type="protein sequence ID" value="PRC91753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91753">
        <property type="protein sequence ID" value="PRC91753"/>
        <property type="gene ID" value="S2091_3508"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035959">
        <property type="entry name" value="RutC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006175">
        <property type="entry name" value="YjgF/YER057c/UK114"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11803">
        <property type="entry name" value="PTHR11803"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01042">
        <property type="entry name" value="Ribonuc_L-PSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55298">
        <property type="entry name" value="SSF55298"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC91753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="131" mass="14605" checksum="4FDC850AD97FA917" modified="2018-07-18" version="1">MMKFLQPDNWVSPKGYANGVSATGRQIFVSGMIGWDEQCQFHTDDFAGQVRQALQNVVAVLHEGGAKPEHIVRMTWYVVNKVEYVAAYPEIGKAYRAIIGRHFPSMTAVQVVALIEDRAKVEIEVTAVVPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVU0</accession>
    <name>A0A2S9GVU0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_3531</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000019">
        <property type="protein sequence ID" value="PRC91776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91776">
        <property type="protein sequence ID" value="PRC91776"/>
        <property type="gene ID" value="S2091_3531"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007390">
        <property type="entry name" value="Spore_V_R"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30029">
        <property type="entry name" value="PTHR30029"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04293">
        <property type="entry name" value="SpoVR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC91776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="516" mass="60875" checksum="EA5D2C54249138DF" modified="2018-07-18" version="1">MTDKKIAKKSAAEKPEPNVNRLPEQSEWTFELLEKVDIEVRRVAKNFGLDTYPNQLEVISAEQMMDAYASVGMPISYYHWSFGKHFLKTEKSYKRGQMGLAYEIVINSNPCIAYLMEENSLTMQTLVIAHAAYGHNSFFKGNYLFRTWTDADAIIDYMLFAKNFIADCEQRYGIDAVEMLLDSCHALQNYGVDRYKRPARISLAKEHLRQREREEYLQSQVNDLWRTVPRRDQAVAGEEIRRVPPEPQENLLYFIEKYSPRLEPWQREIVRVTRKISQYFYPQRQTQVMNEGWATFWHYTILNQLFDEGIVGEGFMMEFLQSHTNVVYQPPITSPHFNGINPYALGFAMMCDIRRICEYPTDEDRHWFPDIAGQDWQKTLDFAMRNFKDESFILQYLSPKLIRDFHFFTVLDDDSQETLEISAIHDDNGYKYLRERLAGQYNLGNREPNIQVWSVDMQGNRSLTLRHAQYQRRPLNQQTNEVLKHVTRLWGFDVYLDTLDESGKVLHRNECKAVRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVU5</accession>
    <name>A0A2S9GVU5_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6">Flagellar basal body rod protein FlgB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_3386</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 6">Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Bacterial flagellum basal body</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the flagella basal body rod proteins family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000018">
        <property type="protein sequence ID" value="PRC91830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91830">
        <property type="protein sequence ID" value="PRC91830"/>
        <property type="gene ID" value="S2091_3386"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030694">
        <property type="term" value="C:bacterial-type flagellum basal body, rod"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071973">
        <property type="term" value="P:bacterial-type flagellum-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001444">
        <property type="entry name" value="Flag_bb_rod_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006300">
        <property type="entry name" value="FlgB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30435:SF12">
        <property type="entry name" value="PTHR30435:SF12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00460">
        <property type="entry name" value="Flg_bb_rod"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002889">
        <property type="entry name" value="Rod_FlgB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01396">
        <property type="entry name" value="FlgB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0975">Bacterial flagellum</keyword>
    <keyword evidence="8" id="KW-0966">Cell projection</keyword>
    <keyword evidence="8" id="KW-0969">Cilium</keyword>
    <keyword evidence="8" id="KW-0282">Flagellum</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flg_bb_rod" evidence="7">
        <location>
            <begin position="13"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00014376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00024934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR002889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC91830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="139" mass="15103" checksum="5D99EB9F8F227159" modified="2018-07-18" version="1">MANGLDELLNLPESALRVREARQELLASNIANADTPNYKARDINFSTALQQVSHAAQAKLGIQAPLALTTTSEGHQTGKIASPMSDAIQYRNDIQGRIDGNDVDTDKERMQFADNGLRYEAAVTLVTAQIHNMLAVIQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GVZ2</accession>
    <name>A0A2S9GVZ2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_3453</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000018">
        <property type="protein sequence ID" value="PRC91897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC91897">
        <property type="protein sequence ID" value="PRC91897"/>
        <property type="gene ID" value="S2091_3453"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015528585" evidence="2">
        <location>
            <begin position="22"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="139"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="140"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC91897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="173" mass="19817" checksum="6BB2AF10C81835E4" modified="2018-07-18" version="1">MNKLRFLLISLLCFAACSVHAMSLFDLRADALMARLPELKKSLNLNANQQILWQQSEAKTRSLMRAKELRRIKLDDLVREMVQTPNVELRDIDAKLDGERQAAQLEDQQSHETWLTMFDALDDKQRVLVQEFLYEQLMRSGNEEKSSADSPGTTSHKGRGARNPADLSKPTQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GX96</accession>
    <name>A0A2S9GX96_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2998</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000014">
        <property type="protein sequence ID" value="PRC92339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92339">
        <property type="protein sequence ID" value="PRC92339"/>
        <property type="gene ID" value="S2091_2998"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015634381" evidence="1">
        <location>
            <begin position="20"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="76" mass="6841" checksum="A3C9D3BC8855C45A" modified="2018-07-18" version="1">MKKSLILVSLLAIALAACGKKEEAAPAPAPAVEVTAPAAASAPAAAPVAADAAASAPVAADAAASAPAAAAPAASK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GXK2</accession>
    <name>A0A2S9GXK2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Catalase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2818</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000013">
        <property type="protein sequence ID" value="PRC92443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92443">
        <property type="protein sequence ID" value="PRC92443"/>
        <property type="gene ID" value="S2091_2818"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004096">
        <property type="term" value="F:catalase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018028">
        <property type="entry name" value="Catalase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011614">
        <property type="entry name" value="Catalase_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020835">
        <property type="entry name" value="Catalase_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00199">
        <property type="entry name" value="Catalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56634">
        <property type="entry name" value="SSF56634"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51402">
        <property type="entry name" value="CATALASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Catalase" evidence="2">
        <location>
            <begin position="51"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="371" mass="40267" checksum="53842CE79554E901" modified="2018-07-18" version="1">MHSPNRAPKSPIKYEASFEVPEDGETETQNELLKTLKHISEVTLKDSGHATRSVHAKSHGLLRGELHVLDGLPAVLAQGIFAKAGDWPVLIRLSTVPGDMLDDSVSTPRGFALKVIGVEGTRLQGSENDVTQDFILVNCGAEFSTPNAKKFLGGLKLLASTTDKVPKLKKALSAVMRGTEKVIESLGGKSATVIGLGGHPETHILGETFFSKAPILFGPYMAKISIVPTSANLKKLTDTPLNVNGKPNGLRDAVVELFAHDTAEWDLRVQLCTDLASMPIEDASVSWPEESSPYLTVARIIAGPQVAWSAERSKAVDDKILFSPWHGIIAHRPIGSIMRIRKAAYEMSAKFRAEHNDLDIIEPKNLDHFPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GY78</accession>
    <name>A0A2S9GY78_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2729</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000012">
        <property type="protein sequence ID" value="PRC92674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92674">
        <property type="protein sequence ID" value="PRC92674"/>
        <property type="gene ID" value="S2091_2729"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC92674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="164" mass="17575" checksum="3F6BB1DD6ADD0117" modified="2018-07-18" version="1">MAGEFKLDVSAMVAKCEGRINEVVQKIVIGISAELMEKSPVGDPVLWKSPPPKGYIGGHFRANWQYAFNVPPGGIIDEIDPSGDATKDEVATRVSSTLGDGTHYLVNNLPYAQRLENGWSTQAPIGMVALTVVDFSLIVNEAANGVQNGTSSEDFAAGFETYKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYC2</accession>
    <name>A0A2S9GYC2_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">CHASE2 domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_2449</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000011">
        <property type="protein sequence ID" value="PRC92719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92719">
        <property type="protein sequence ID" value="PRC92719"/>
        <property type="gene ID" value="S2091_2449"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004016">
        <property type="term" value="F:adenylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009190">
        <property type="term" value="P:cyclic nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07302">
        <property type="entry name" value="CHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001054">
        <property type="entry name" value="A/G_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007890">
        <property type="entry name" value="CHASE2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05226">
        <property type="entry name" value="CHASE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00211">
        <property type="entry name" value="Guanylate_cyc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01080">
        <property type="entry name" value="CHASE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00044">
        <property type="entry name" value="CYCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50125">
        <property type="entry name" value="GUANYLATE_CYCLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="326"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="352"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="381"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="domain" description="Guanylate cyclase" evidence="2">
        <location>
            <begin position="444"/>
            <end position="578"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC92719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="628" mass="69751" checksum="6AAA0E4DA835369D" modified="2018-07-18" version="1">MSNSTAKFGLGMLLQWQVLACLLFASAFALELFWLHRLQTTEARLTDAFMRRHAAEYIPDPDIVVVDIDNASMTEMEAIAGLWAWPREIHADLLEGLSEFAPRAIVFDIAFSERDMKRPKSDARLSEQVAASPTHSIYLPATLLNERGDAPPVALQSVAQAFAMHGSHVSTTAATLQLPQAVQPAAWRLGLINNLDDADGVLRRYRLYNDVAGWRIPSLPARVASDLGFAVPVGSDFTLRWPDLGHKRYRYSELYKLLTEHRPDLKPAEVLRLAHEFRDKIIFIGASASSSFDHHLSPLGSGYVGVDVLAVALDNLKNGRVMRQSAPHWIFLCGLGLLLAQVLAFQQRVHPLIIGAALVVTTLGGVWLADMALHRDLIMPIITPFIFVWIWYLGAALVGYLRERRTRDQAVALFRRFLNPGVVRKIVEQGETVESLSGQMRNVTVLFSDIRDFTTLSESSPPQQVVALLNRYFERQVEIIFKHRGTLDKFIGDCIMAFWGAPFDDPQQAQNAVAAALDMQDALLEFNQELKAENPNAANFDIGIGLHFGPAVIGFIGAQRKLDYTAIGDTVNLASRVEGLTKGVSRILVTREVKDACAAVHEFTLCGTYAVKGRYAQVELYAPSRKIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GYX3</accession>
    <name>A0A2S9GYX3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_2351</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000010">
        <property type="protein sequence ID" value="PRC92934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC92934">
        <property type="protein sequence ID" value="PRC92934"/>
        <property type="gene ID" value="S2091_2351"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015517240" evidence="1">
        <location>
            <begin position="25"/>
            <end position="548"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC92934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="548" mass="59314" checksum="906CA950C34CAE25" modified="2018-07-18" version="1">MSKSHRYVALLGSFCVIIGTAVQAAEVKVEINLAAPDGVEVSYTLPDQCKELPFENKSRSDEPIRATWQALDDCGSVTGDVLSRTKNTCSVMRFRVPATSNTPPGYYPSAFPLIGGVYVHTSNYAVSESCGKLSYRFVAPGIAAAGHAYKGSVIADTQATGDASALLMQEPVESTGGTIAYFDPRLSPVAVEQIKEVADGTVSYLKTVLPDAVFKAPILAAVAASEPGGPNIRGNAGDVLLASFYNWPQQPGPKEREKLTLLVAHEFSHRFQLRDAVDVYTDSRLIHEGGAEFLRWLTSIQKGWLSREEAAAQVDDALTQCILYTNRQDWHGLTPKAIAGNRLEYVCGLPVYVYGLAARQGQGSAFARFNDFYKELRAGKTPDFAHTLECGANAQCQARWFPSLLGAGVPMETQWGKLAQETGFAKAHAPNQSQRDRMVLQSIVKLMRDDCGGRRSTTETPNGVLIDGLSMCKTLRADIDVRQIEDQPVFGGESTLAAMVAACTDRHEVKLGAKNGGSLTVPCGEPYSVRSEFYGIDIDKVLKSLLQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9GZC3</accession>
    <name>A0A2S9GZC3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phage protein, HK97 gp10 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2171</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000009">
        <property type="protein sequence ID" value="PRC93085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93085">
        <property type="protein sequence ID" value="PRC93085"/>
        <property type="gene ID" value="S2091_2171"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010064">
        <property type="entry name" value="HK97-gp10_tail"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04883">
        <property type="entry name" value="HK97-gp10_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01725">
        <property type="entry name" value="phge_HK97_gp10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="131" mass="14783" checksum="AACBB9FAE64E8D97" modified="2018-07-18" version="1">MANFDIEMSGDLFGVLTKFESKVREKVLFSGAAAMAKVIYDEAKINALKHTKSGTLYDAIYRVHSKDKSTEQKVTYEISWNKTRAPHGHLIEFGTVRAPAYPFIRPAFDRISDAIKAGQDRMREALNKRAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H001</accession>
    <name>A0A2S9H001_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_2050</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000008">
        <property type="protein sequence ID" value="PRC93312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93312">
        <property type="protein sequence ID" value="PRC93312"/>
        <property type="gene ID" value="S2091_2050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="170" mass="18308" checksum="3561D0DD5DB6C125" modified="2018-07-18" version="1">MLKLTIAFLLALSITACSPKFDWRDVRGGESPYTVLMPAKPALLSREIQLGQQTVTMHMTGAQIDGVSFAVGAVKLPDAAQAQTALTNIKIALLKNISGTITHEKTSANTSESKLTINTDFDAISTTTTTRMVGRLVARDVWVFQVVVVGPEKAINKDAVDTFLSSFKPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0B3</accession>
    <name>A0A2S9H0B3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ferritin-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_1811</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93424">
        <property type="protein sequence ID" value="PRC93424"/>
        <property type="gene ID" value="S2091_1811"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012347">
        <property type="entry name" value="Ferritin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026820">
        <property type="entry name" value="VioB/RebD_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12902">
        <property type="entry name" value="Ferritin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ferritin-like" evidence="1">
        <location>
            <begin position="25"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC93424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="345" mass="37930" checksum="12946B4BBE25BC71" modified="2018-07-18" version="1">MIKLDKRFVEAIESATTPDDLFQSLQNAIELEHSTIPPYLTAVLSLKQGKNDEIATLIRGIMGQEMLHMCIACNILIAIGGTPRINTRGFAPDYPGPLPMHIGGVGFTVGIEAFSKSLVKNTFMVIEEPENPIPVKDPKLMTAAQQDYATIGAFYAALQKKIREMGDGIFVPNLKDQVLRGKWFPADQLFPITDVRSANKAIEIIIVQGEGTSSLPYQGASDPAHYYKFGEIAAGHRMIQTPEGYAYRGAPIPFDDNEVYNLKPNCKIADFPPGSQASTRLTQFNTTYNTLLNTLHLCFNGQPDLLDTAIGVMYSLRIESVALMQTPIAPGSSHMVGPSYEYRKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H0B6</accession>
    <name>A0A2S9H0B6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Amino acid transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">S2091_1777</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000007">
        <property type="protein sequence ID" value="PRC93390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93390">
        <property type="protein sequence ID" value="PRC93390"/>
        <property type="gene ID" value="S2091_1777"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="42"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="74"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="115"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="163"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="198"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="226"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="267"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="313"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="370"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="392"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="424"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="449"/>
            <end position="467"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PRC93390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="477" mass="50955" checksum="892DCC203DAACB38" modified="2018-07-18" version="1">MSISTKLSTPSLFERMLRTKPIDAMPTHGEEATGGLHRTIGLFQLTMFGVGATIGSGIFVILGDAVPKAGPGVILSFIIAGITAALTALCYAELASSIPSTGSSYSYTYATMGEMVAYLVGWCLLLEYGISTSAIAVGWGQYLNELSFDLLGMRMPAAIANPPGVNGGIFNLPAVVLVFMCCVLLLRGTKESARVNAIMVVVKIAVLIMFILIGLTAFHSSNLHPFMPMGMSGVGAAASSIFFSYIGLDTIATASDEVKNPKRTLPLAILFSLAIVTAVYVLVAIVGVGSQPYTEFNGNEAGLVQILRRITGATWPGVILAMGAVISIFSITLVTLYGQTRILYAMARDGMLPKIFAKVDAHTKTPRKNTVIVGTLVAIAAALLPLDVLADLTSMGTLVAFAIVSTGVIILRRTRPDLPRGFKVPFYPLFPILSVLFCIYLIADLPTHTFTLFAVWLSFALIFYFSYSMRNSKLENV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H106</accession>
    <name>A0A2S9H106_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cytochrome B561</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_1634</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000006">
        <property type="protein sequence ID" value="PRC93633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93633">
        <property type="protein sequence ID" value="PRC93633"/>
        <property type="gene ID" value="S2091_1634"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022904">
        <property type="term" value="P:respiratory electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011577">
        <property type="entry name" value="Cyt_b561_bac/Ni-Hgenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016174">
        <property type="entry name" value="Di-haem_cyt_TM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01292">
        <property type="entry name" value="Ni_hydr_CYTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81342">
        <property type="entry name" value="SSF81342"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="45"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="89"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="138"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="domain" description="Ni_hydr_CYTB" evidence="3">
        <location>
            <begin position="4"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC93633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="174" mass="19922" checksum="8FF0D5382BEC29DF" modified="2018-07-18" version="1">MKKYTKTAMFFHWLTALLIIAAFWLGLTMVDIPGITPTKLRYFSWHKWLGITILGLSCLRLLWRLGNRPPEYPANMTSWQKKAASGLHILLYVLIFSIPISGYLYSLASGIPVIYLGIFPLPVIMDPNPELKPLLKQLHYVLNMTLLASFCLHVLAALKHQFFDRDGVLKRILP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H1M7</accession>
    <name>A0A2S9H1M7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_1500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000005">
        <property type="protein sequence ID" value="PRC93891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC93891">
        <property type="protein sequence ID" value="PRC93891"/>
        <property type="gene ID" value="S2091_1500"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC93891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="166" mass="19311" checksum="98017E025D487BDD" modified="2018-07-18" version="1">MDLRKIKNDYKLLFSSELNFFRDPRYGLILGVPMGLEDNSSQDFFQICEPHENTYFTASMYHVNGMTLSGWAKIRYSTVEQKMPYLEMVCEPYQVNGANWIGFAAEYEGTFPGNDYVSRYLVLCFCQGVNLISFTITARRDKFEENVELYNWIIKNALILEVLGTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2F4</accession>
    <name>A0A2S9H2F4_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Protein translocase subunit SecE</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">secE</name>
        <name evidence="8" type="ORF">S2091_1335</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the SecE/SEC61-gamma family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000004">
        <property type="protein sequence ID" value="PRC94162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94162">
        <property type="protein sequence ID" value="PRC94162"/>
        <property type="gene ID" value="S2091_1335"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008320">
        <property type="term" value="F:protein transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0065002">
        <property type="term" value="P:intracellular protein transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006605">
        <property type="term" value="P:protein targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043952">
        <property type="term" value="P:protein transport by the Sec complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1030">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00422">
        <property type="entry name" value="SecE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005807">
        <property type="entry name" value="SecE_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038379">
        <property type="entry name" value="SecE_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001901">
        <property type="entry name" value="Translocase_SecE/Sec61-g"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33910">
        <property type="entry name" value="PTHR33910"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00584">
        <property type="entry name" value="SecE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01650">
        <property type="entry name" value="SECETRNLCASE"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00964">
        <property type="entry name" value="secE_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0811">Translocation</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="18"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="43"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="88"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC94162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="126" mass="13680" checksum="90B79E392FBDD39B" modified="2018-07-18" version="1">MSNNSVQTVSTSSDKLKITLAVIAAVAGVVGFFVLSDQSALRIAALVVGLLVAIAFVWTSEPGQSFLTFGKEAVRETKKVVWPTRKEAGQITAVVFGFVLVMALFLWGTDKILEFVLYDLILGWKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2J7</accession>
    <name>A0A2S9H2J7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0809</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94188">
        <property type="protein sequence ID" value="PRC94188"/>
        <property type="gene ID" value="S2091_0809"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="86" mass="9940" checksum="DD97534B32ACB44A" modified="2018-07-18" version="1">MGVGQKQRQKQRQEQRQEQRQEQRQEQRQEQRQEQQQHIQTSTITVRKKKKPIRYRSSPAYGLSTPSVAKISASNPSISTASSSSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2K4</accession>
    <name>A0A2S9H2K4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">MatE: MATE efflux family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0830</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94209">
        <property type="protein sequence ID" value="PRC94209"/>
        <property type="gene ID" value="S2091_0830"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042910">
        <property type="term" value="F:xenobiotic transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002528">
        <property type="entry name" value="MATE_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01554">
        <property type="entry name" value="MatE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00797">
        <property type="entry name" value="matE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="65"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="105"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="130"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="162"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="240"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="284"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="328"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="361"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="387"/>
            <end position="409"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="420" mass="44262" checksum="684A8501D7DFD5A8" modified="2018-07-18" version="1">MSLTDAAFVGHISSKELAAVGLSMGSLFPLLFGAIALVSTGGIFVAEAQVNKNHLEVKSSLDLSLWTCILFSPLLMFGGAMLPALFEITGQDSSIVNLSSQYLNVVIWSIPPILGFSVFRTFVAALNKNSIVFSVSLVGVVLNAVLNYILVFGKFGAPALGIVGSAISTTVSSAIMLALMALYCARRLDYRFSLSTYSVVKSFAALELLRLGGPAFGIGLIESSQFGIVTILAGQYGVNFLAATTIAIFVSDLFIVIALGLGDQLTVDIAAFAASGDRVSCRKLAIAGIGLMTLTCVPMAAACIFYPNVLVSMFLDSSNVDAASVLNISQELLAVLAVFLFADGAQVVLSRSLKGLRDTLVPMWIAATGYWIVGIGGGWWLANRAEWGGIGLWYGLAAGLTLSSVAMGFRMHFKVKSTEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H2U3</accession>
    <name>A0A2S9H2U3_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0923</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94302">
        <property type="protein sequence ID" value="PRC94302"/>
        <property type="gene ID" value="S2091_0923"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="96"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="161" mass="18188" checksum="0C1597EDA9D2B18D" modified="2018-07-18" version="1">MDASPHLSSVLKLYFGTLRCRCGREASITLTYLAEPSKVLQKNNEQVYLRMVEQTKQIAVAHMPMLKRDLTEFAKSIKHQINTESSSKPVDRVKQFNIVGIAVIATLFGIFIGSTWFGQGTNQSREEEKKLEMGNSIAKVIPLLDKTTKDKIIQLMEENSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3E0</accession>
    <name>A0A2S9H3E0_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Bacterial SH3 domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_1074</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000003">
        <property type="protein sequence ID" value="PRC94453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94453">
        <property type="protein sequence ID" value="PRC94453"/>
        <property type="gene ID" value="S2091_1074"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010466">
        <property type="entry name" value="DUF1058"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003646">
        <property type="entry name" value="SH3-like_bac-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06347">
        <property type="entry name" value="SH3_4"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51781">
        <property type="entry name" value="SH3B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015666010" evidence="1">
        <location>
            <begin position="24"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="domain" description="SH3b" evidence="2">
        <location>
            <begin position="84"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="149" mass="16317" checksum="F699E03B2339B6E9" modified="2018-07-18" version="1">MKSQTRLVILALAACGYASGAFALDFKNVGASPVIMYDAPSIRGQKLFIAPRGMPVEVVINYGAWSKVRDFAGDLSWIETKQLSERKNILVRNLNAKIRITADDYSEVVFSADKGVVLELVDTVIPGWAKVKHSDGATGYVRLNDVWGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3G1</accession>
    <name>A0A2S9H3G1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative NADP-dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0522</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94519">
        <property type="protein sequence ID" value="PRC94519"/>
        <property type="gene ID" value="S2091_0522"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016628">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041694">
        <property type="entry name" value="ADH_N_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045010">
        <property type="entry name" value="MDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43205">
        <property type="entry name" value="PTHR43205"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16884">
        <property type="entry name" value="ADH_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PKS_ER" evidence="1">
        <location>
            <begin position="26"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC94519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="350" mass="37878" checksum="C5915006DBAB0FBD" modified="2018-07-18" version="1">MSATSLTTLPATITNSQWIYLRHPDGIVGPEHYELRTQTLATELSAGEVLVESHYLSVDPYMRINQSLKPTYNELPHALNTVQSAGVVARVLSSSVPHLAAGDWVEGMIGWQTHARIHHSMLRKLDPAVAPVSTALGVLGMPGRTAWFGLTESGRPHAGEVVVVSGAAGAVGSLVAQFAKRHGCKVLGIAGGAAKCDWLRDNLGLDWAVDYKAHHSAEALSAQIKQLTGGVDVYFDNVGGMVTDAIIPLINRRARIVICGSISQYSGGLDQPELGPRFLHHMLYQRATIQGMLARDYVHRMDEMQRIVGPMVTAGQIVFEETIVQGFELLPATLNSLFTGDHRGKLLVQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3K8</accession>
    <name>A0A2S9H3K8_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ABC-type transport system involved in resistance to organic solvents ATPase component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">S2091_0561</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94558">
        <property type="protein sequence ID" value="PRC94558"/>
        <property type="gene ID" value="S2091_0561"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030296">
        <property type="entry name" value="MlaF/Mkl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43023:SF6">
        <property type="entry name" value="PTHR43023:SF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-1278">Translocase</keyword>
    <feature type="domain" description="ABC transporter" evidence="7">
        <location>
            <begin position="22"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="54"/>
            <end position="61"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PRC94558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="274" mass="29992" checksum="D5634BFD0BAFE07E" modified="2018-07-18" version="1">MSTTLNTLVNTPQPAPHAEAIIQVKHLRTQFGRTVIHNHLELDIYRGEILSIVGGSGTGKTVLLRQMLRLEAPKQGTITIFGVDIHHATSEQVAYFRSRSGMLFQHGALYSALSVFDNVAQPMRELRILPEALIKDAVYLKLDMAGIAPEHAQKMPSSLSGGMVKRVALARALALEPELLFLDEPTAGLDPDSSETFVSLIQSLHKELGLTVVMVTHDLDTLFALSSRIAVLADKHVVALGTTDEVILHPHPFIQEFFLGARGKRALTALQNTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3Q1</accession>
    <name>A0A2S9H3Q1_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">S2091_0618</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94615">
        <property type="protein sequence ID" value="PRC94615"/>
        <property type="gene ID" value="S2091_0618"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PRC94615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="88" mass="10248" checksum="38B183C189A41BAC" modified="2018-07-18" version="1">MQDPKLCDCHGKPVAIGDIVRIVTLNQEFIENFPSEERILIESMIGQFFKIYGIDEFGQPWVSKEWHDEDGVMQTHIIALDPEEMERI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H3R4</accession>
    <name>A0A2S9H3R4_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="10">FtsX-like permease family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">S2091_0625</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94622">
        <property type="protein sequence ID" value="PRC94622"/>
        <property type="gene ID" value="S2091_0625"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025857">
        <property type="entry name" value="MacB_PCD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12704">
        <property type="entry name" value="MacB_PCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="285"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="332"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="375"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="domain" description="MacB_PCD" evidence="9">
        <location>
            <begin position="49"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="8">
        <location>
            <begin position="316"/>
            <end position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF12704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PRC94622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="410" mass="44760" checksum="79D7353B7D1B4226" modified="2018-07-18" version="1">MEIRPIVSALLRNKMAPLLVAIQIALSLAILSNALYIVNLRIDAAHRPSGLADEASTFYMRISSNQTMSLVEQNDNQKRLLQAITSVAGVVSAADVSQMPMSQSGWDSSIALDRKQTQSSVEASMYQSSGSLVNGFGLKLLAGRDFNSADVIEQDPDSDLKIPENVIVTQTLAQDLYPNEKNYIGKSFFWGTGPDAKESHIVGVVERLQTSSAQISAEGEYSMLLPIRTPTSYPMFVIRAEPGQRDRVISEVEAAVRKADVFPLRINTKTTEKDRQIRYGNEMALVWMLVVVSTLLLLITASGIVGMTSLWVSQRRKQIGVRRALGARKIDILRYFITENLIISCMGVVSGSLLAIGLNQLLVSQLELTKLPFSYVFSGAVLFLLLGVGAAYAPSWRAASISPAVATRST</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H482</accession>
    <name>A0A2S9H482_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Tfp pilus assembly protein PilN</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">S2091_0783</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000002">
        <property type="protein sequence ID" value="PRC94780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94780">
        <property type="protein sequence ID" value="PRC94780"/>
        <property type="gene ID" value="S2091_0783"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007813">
        <property type="entry name" value="PilN"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05137">
        <property type="entry name" value="PilN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="187"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="57"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PRC94780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="210" mass="23395" checksum="587A3A3C97DA56B2" modified="2018-07-18" version="1">MIKINLLPHREERRKQRRNDFYTLLVFASIVAVLILLLVGFYNASQISLQNQQNHLIKSANDKLDEEIKEIATLREEIDGLKARQQAVEDLQGDRNQPVYLLSELVAQTPEGIYLRSVKQDGQHIVLTGYAQSNERVSEYLKNLGSHSDWLNKPDLIVINATGIGQGKDAKKVFDFTVNVAIKRPRDQEAAGAATATPAIAPANGQAVKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4K7</accession>
    <name>A0A2S9H4K7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Regulator of competence-specific protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0093</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94898">
        <property type="protein sequence ID" value="PRC94898"/>
        <property type="gene ID" value="S2091_0093"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007076">
        <property type="entry name" value="TfoX_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04993">
        <property type="entry name" value="TfoX_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TfoX_N" evidence="2">
        <location>
            <begin position="11"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="107"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC94898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="131" mass="14711" checksum="C5A88B8924CF88D9" modified="2018-07-18" version="1">MSSDFVAYVHELLAPLGNVRSKRMFGGVGIYINDLFCALIADDYLYFKGDDENEAEFIAVDCPPFTYEKEGQLFSMRYYRAPDEALDNPHEMSRWARLGLAAALRKAANPKAKAKKAQPKVSKKLSPTQLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4X0</accession>
    <name>A0A2S9H4X0_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF5668 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">S2091_0227</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">S20-91</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95032">
        <property type="protein sequence ID" value="PRC95032"/>
        <property type="gene ID" value="S2091_0227"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043726">
        <property type="entry name" value="DUF5668"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18917">
        <property type="entry name" value="DUF5668"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="24"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="79"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="102"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="DUF5668" evidence="2">
        <location>
            <begin position="24"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PRC95032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="132" mass="15179" checksum="1BB376A0A6C7FA30" modified="2018-07-18" version="1">MNNDQLTQLKCYQEGASYHASKKIFFGLALIIVGSLFLLERFNIIENNSMMNYWPLILAMFGLNKLLFSQNTHRKISGFFQILLSFWLFACLAHLWGWTFAVTWPIILIALGLCYITTTLFIKNSVNNESAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4Y6</accession>
    <name>A0A2S9H4Y6_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ribosome maturation factor RimM</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">rimM</name>
        <name evidence="5" type="ORF">S2091_0188</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Binds ribosomal protein S19.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="2">The PRC barrel domain binds ribosomal protein S19.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RimM family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC94993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC94993">
        <property type="protein sequence ID" value="PRC94993"/>
        <property type="gene ID" value="S2091_0188"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042274">
        <property type="term" value="P:ribosomal small subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00014">
        <property type="entry name" value="Ribosome_mat_RimM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011961">
        <property type="entry name" value="16S_RimM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027275">
        <property type="entry name" value="PRC-brl_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011033">
        <property type="entry name" value="PRC_barrel-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002676">
        <property type="entry name" value="RimM_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036976">
        <property type="entry name" value="RimM_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05239">
        <property type="entry name" value="PRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01782">
        <property type="entry name" value="RimM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50346">
        <property type="entry name" value="SSF50346"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02273">
        <property type="entry name" value="16S_RimM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0143">Chaperone</keyword>
    <keyword evidence="1 2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="RimM" evidence="3">
        <location>
            <begin position="24"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="domain" description="PRC" evidence="4">
        <location>
            <begin position="119"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF05239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC94993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="209" mass="22777" checksum="11BD446392B81920" modified="2018-07-18" version="1">MSESKTLTSSLATPTPLPADLISVGHITGAYGVQGWVRIHPYSAEADALLHAKTWWLGKPEVRSEAPANVHDVEKLEAKRHGDDVVARLMGVVGRDAAEGLKGTVVQISRSHFPVLSNNEFYWLDLIGLAVENLQGESLGVVADLIDNGAHPILRVVQSNPVKVEINSAQEAEVVPAAAREYLIPFVERFVPNVDQQSKKITVDWGLDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H4Z7</accession>
    <name>A0A2S9H4Z7_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Aspartate/tyrosine/aromatic aminotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">S2091_0232</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">S20-91</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95037">
        <property type="protein sequence ID" value="PRC95037"/>
        <property type="gene ID" value="S2091_0232"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:cellular amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000796">
        <property type="entry name" value="Asp_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11879">
        <property type="entry name" value="PTHR11879"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00799">
        <property type="entry name" value="TRANSAMINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="4">
        <location>
            <begin position="26"/>
            <end position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PRC95037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="397" mass="43379" checksum="E7344FE66E53F384" modified="2018-07-18" version="1">MFLHVEPYAGDPILSLNEAFGKDPRTNKINLSIGIYFDDAGKIPMLPSVRAAELKVVAEAGARPYLPMEGAANFRTAVQHLLFGAEHAALQAGRVVTIQTVGSSGGLKVGADFIKRYFPNTTILVSDPTWDNHRAVFEGSNLTVETYPYYDADTGGLRFDAMLAALSKAEKHSVVLLHACCHNPTGVDLNNEQWQQLLPVLQERELIPFLDLAYQGYGAGIQEDAYAVRLFADSGISFFVANSFSKSMSLYGERCGALSVVCPDAAQAVNVLGQLKANIRRNYSNPPMHGGQLVARVLTDPELRAQWEAEVSAMRLRIQAMRRQLHAVLSAKLPGRDFSYFLTQHGMFSYTGLNPAQCDRLKEEFGVYILRSGRMCVAGLNTSNVEATANAMAAVLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H504</accession>
    <name>A0A2S9H504_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Short-chain alcohol dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">S2091_0216</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">S20-91</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95021">
        <property type="protein sequence ID" value="PRC95021"/>
        <property type="gene ID" value="S2091_0216"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PRC95021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="280" mass="29771" checksum="F8FABC7315FDBE1B" modified="2018-07-18" version="1">MQNLSQKVAVITGAAEGIGKAIALACAAEGMKLVLADIDADKLAATVAEISARDTEVIGQVTDVSKSSAVDALADAAFARFGQVNLLVNNAGVAFAKNAWETTEEDWNWLMGINLYGVTHALRAFIPRMLAGGADGHIVNTASIAGLISEPSLAAYNVSKFGVVTLSEGLQHDLVLRKANINVSVLCPGWVNTRIIESERHRASEDRTDVAKLDKVSIKTGLAVTKAVQAGMSAEQVASATLDAVKHNQFYILTHPYTIQGIEVRMQDILQQRAPTLLPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2021-09-29" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5C6</accession>
    <name>A0A2S9H5C6_9BURK</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major Facilitator Superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">S2091_0384</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">S20-91</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95189">
        <property type="protein sequence ID" value="PRC95189"/>
        <property type="gene ID" value="S2091_0384"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="63"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="96"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="118"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="156"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="197"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="262"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="305"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="335"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="360"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="393"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="425"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="258"/>
            <end position="451"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PRC95189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="451" mass="50244" checksum="AE9B035420384305" modified="2018-07-18" version="1">MQTKLKMPLNDDIANYAKKPMLSFWQIWNMSFGFLGIQFGFALQNSNVSRIFETLGAKIDDLPILWIAAPCTGLLIQPLIGFLSDRTWNRFGRRRPYFLIGAILASLALIAMPNSKALWVATVILWILDSSINISMEPFRAFVGDMLPQKQLTNGFAFQSFFIGIGAVVASALPYMLSNWFHVENSALPGHLPDSVVYSFYLGAIAFLSAVVWTVIKTKEYSPQELRQQDPEAWKNIDSEKQPSWLSIFSDFRHMPKTMVQLAFVQFFTWFALFAMWIYTTSAVTKHIYHSVDPSTALYNDGANWVGVCFAVYNGFSAIFAFALPWLAKRTSRKMTHAISLIVGGCSLISIYFVTTPEMLIVSMMGIGMAWASILSMPYAILAGALPANKMGLYMGTFNFFIVIPQILAASILGFFTKNLFHGEAVLTLALGGFSMLVAAALVMNVQDKNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S9H5H5</accession>
    <name>A0A2S9H5H5_9BURK</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Glucokinase</fullName>
            <ecNumber evidence="9">2.7.1.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Glucose kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">glk</name>
        <name evidence="12" type="ORF">S2091_0378</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Solimicrobium silvestre</name>
        <dbReference type="NCBI Taxonomy" id="2099400"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Betaproteobacteria</taxon>
            <taxon>Burkholderiales</taxon>
            <taxon>Oxalobacteraceae</taxon>
            <taxon>Solimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Solimicrobium silvestre gen. nov., sp. nov., isolated from alpine forest soil.</title>
            <authorList>
                <person name="Margesin R."/>
                <person name="Albuquerque L."/>
                <person name="Zhang D.-C."/>
                <person name="Froufe H.J.C."/>
                <person name="Severino R."/>
                <person name="Roxo I."/>
                <person name="Egas C."/>
                <person name="Da Costa M.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">S20-91</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>ATP + D-glucose = ADP + D-glucose 6-phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17825"/>
            <dbReference type="ChEBI" id="CHEBI:4167"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61548"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.2"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the bacterial glucokinase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">In the N-terminal section; belongs to the bacterial glucokinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.2" evidence="9"/>
    <dbReference type="EMBL" id="PUGF01000001">
        <property type="protein sequence ID" value="PRC95183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PRC95183">
        <property type="protein sequence ID" value="PRC95183"/>
        <property type="gene ID" value="S2091_0378"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000237839">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004340">
        <property type="term" value="F:glucokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005536">
        <property type="term" value="F:glucose binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd05013">
        <property type="entry name" value="SIS_RpiR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00524">
        <property type="entry name" value="Glucokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003836">
        <property type="entry name" value="Glucokinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000281">
        <property type="entry name" value="HTH_RpiR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035472">
        <property type="entry name" value="RpiR-like_SIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001347">
        <property type="entry name" value="SIS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046348">
        <property type="entry name" value="SIS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02685">
        <property type="entry name" value="Glucokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01418">
        <property type="entry name" value="HTH_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01380">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53697">
        <property type="entry name" value="SSF53697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00749">
        <property type="entry name" value="glk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51071">
        <property type="entry name" value="HTH_RPIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51464">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6 9" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="3 9 12" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HTH rpiR-type" evidence="10">
        <location>
            <begin position="332"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="domain" description="SIS" evidence="11">
        <location>
            <begin position="452"/>
            <end position="591"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PRC95183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000237839"/>
        </source>
    </evidence>
    <sequence length="642" mass="69398" checksum="A482EBB076B60633" modified="2018-07-18" version="1">MIPFDNPRLIADIGATYARFALETSRGEFAQITSLPCADYPDFYSAITNYMSTLKPIQILHAAIAVANPVVGDSVIMTNYHWQFSIESMRIQLGLETLVIVNDFTALAMAVPRLGAQDIRKIGGGVAIDHTKQSVIGILGPGSGLGVSGLIPAGDGWVSLGSEGGHSSFSPRNEREIAVLRYAWKSFDHVSFERLLSGPGMELMYRALADYANVPGKNLTAAEITDCALNNTDSVCVETLELFCSLLGTAAANLAVTLGALGGIYIGGGIIPRLGSYFEQSPFRARFEQKGRFSSYLQAIPTFVITAEHATFIGISEILEAQLRNLQAKPGSAILGQIRRARPDLSPAELRVAEYVLAHPRTVLNAPIIDIAKTAQVSQPTVIRFCRSLGCEGLSDFKLRLASGLTSTIPLTHTQVTREDSMLELAAKVLGNTASAILQVRNQINRDMVDRAIEMLNHANRVEFFSVGHYGVIAQDAQFKFLRLGVSSGAYTDQKLQLLAAGVLKQDDVVVIISSSGRIQELVDVAEKARERGASIIAITSSHSPLARKADVALIIDHVEDISTHLPMVSRILHLLMIDILAVGVAMRRKSENMQLLNTESDELIDVSKKTIINPASEKLSTDDIPGVSLSSPLSNLTSHSR</sequence>
</entry>
<copyright>
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms Distributed under the Creative Commons Attribution (CC BY 4.0) License
</copyright>
</uniprot>